# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- GLEYA PF10528.9 KKA00950.1 - 3.2e-21 75.6 0.4 3.2e-21 75.6 0.4 2.7 3 1 0 3 3 3 1 GLEYA domain PA14 PF07691.12 KKA00950.1 - 4.5e-06 26.5 0.0 2.5e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 PA14 domain Flocculin PF00624.18 KKA00950.1 - 0.0015 18.7 23.9 0.0015 18.7 23.9 4.5 5 0 0 5 5 5 2 Flocculin repeat Thioredoxin PF00085.20 KKA00951.1 - 2.1e-24 85.4 0.1 3.4e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKA00951.1 - 1e-05 25.9 0.3 3.1e-05 24.4 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KKA00951.1 - 8e-05 22.1 0.6 0.00016 21.1 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KKA00951.1 - 0.00043 20.0 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 KKA00951.1 - 0.0008 19.3 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 KKA00951.1 - 0.00088 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KKA00951.1 - 0.0024 18.1 0.1 0.0085 16.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KKA00951.1 - 0.041 13.9 0.4 0.07 13.2 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.6 KKA00951.1 - 0.05 13.3 0.5 0.42 10.3 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin Flocculin PF00624.18 KKA00952.1 - 2.3e-91 299.8 277.8 1.6e-09 37.9 9.8 13.1 13 0 0 13 13 13 13 Flocculin repeat Pab87_oct PF13969.6 KKA00952.1 - 0.034 14.2 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 Pab87 octamerisation domain 2OG-FeII_Oxy_5 PF13759.6 KKA00952.1 - 0.059 13.8 12.0 40 4.7 0.1 5.8 6 0 0 6 6 6 0 Putative 2OG-Fe(II) oxygenase CEL_III_C PF18054.1 KKA00952.1 - 1.1 9.3 10.6 11 6.0 1.7 3.6 2 0 0 2 2 2 0 CEL-III C-terminal Flocculin PF00624.18 KKA00953.1 - 2.5e-11 43.6 111.8 5.9e-06 26.4 22.6 9.5 8 2 1 9 9 9 5 Flocculin repeat RT_RNaseH_2 PF17919.1 KKA00955.1 - 4.9e-28 97.1 0.0 1.3e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKA00955.1 - 5.6e-26 90.9 0.0 1.8e-25 89.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KKA00955.1 - 4.4e-11 42.7 0.0 9.1e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KKA00955.1 - 8.8e-11 41.8 0.2 3e-10 40.0 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KKA00955.1 - 8.2e-10 38.9 0.1 1.7e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KKA00955.1 - 0.0076 16.4 0.2 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 KKA00955.1 - 4.5 7.1 7.8 0.15 11.9 0.5 2.3 3 0 0 3 3 3 0 Integrase core domain GLEYA PF10528.9 KKA00957.1 - 2e-15 57.0 2.9 2e-15 57.0 2.9 2.7 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.12 KKA00957.1 - 1e-08 35.1 0.1 3e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 PA14 domain Glyco_hydro_3_C PF01915.22 KKA00958.1 - 2.3e-54 184.5 0.0 4.8e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKA00958.1 - 3.6e-28 98.9 0.0 7.3e-28 97.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKA00958.1 - 8.7e-20 70.6 0.5 3e-19 68.9 0.5 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KKA00958.1 - 1.7e-12 47.3 0.1 3.5e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KKA00959.1 - 4.9e-15 55.7 0.1 7.2e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KKA00959.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 PA14 domain CBP_BcsN PF17038.5 KKA00960.1 - 0.02 14.3 0.2 0.028 13.8 0.2 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN Rota_NSP4 PF01452.16 KKA00961.1 - 0.039 13.6 0.2 0.056 13.1 0.2 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein Flocculin PF00624.18 KKA00962.1 - 1.5e-150 489.2 464.9 2.9e-09 37.0 9.8 22.1 22 0 0 22 22 22 21 Flocculin repeat Pab87_oct PF13969.6 KKA00962.1 - 0.001 19.1 0.1 32 4.7 0.0 3.7 3 0 0 3 3 3 3 Pab87 octamerisation domain DUF5091 PF17012.5 KKA00962.1 - 0.062 13.6 1.0 95 3.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5091) 2OG-FeII_Oxy_5 PF13759.6 KKA00962.1 - 0.31 11.5 28.8 73 3.9 0.1 9.7 11 0 0 11 11 11 0 Putative 2OG-Fe(II) oxygenase Flocculin PF00624.18 KKA00963.1 - 9.9e-32 108.9 230.7 2.5e-06 27.6 23.8 9.5 9 1 0 9 9 9 7 Flocculin repeat GLEYA PF10528.9 KKA00963.1 - 6.2e-20 71.4 0.7 6.2e-20 71.4 0.7 3.0 3 1 1 4 4 4 1 GLEYA domain PA14 PF07691.12 KKA00963.1 - 3.4e-07 30.2 0.0 3.4e-07 30.2 0.0 3.2 3 1 0 3 3 3 1 PA14 domain Flocculin PF00624.18 KKA00964.1 - 1.4e-65 217.3 181.8 1.1e-09 38.4 9.8 9.3 9 0 0 9 9 9 9 Flocculin repeat 2OG-FeII_Oxy_5 PF13759.6 KKA00964.1 - 0.016 15.6 6.6 27 5.2 0.1 5.0 5 0 0 5 5 5 0 Putative 2OG-Fe(II) oxygenase Flocculin PF00624.18 KKA00965.1 - 3.3e-64 212.9 178.1 9.1e-10 38.6 9.8 9.1 9 0 0 9 9 9 8 Flocculin repeat 2OG-FeII_Oxy_5 PF13759.6 KKA00965.1 - 0.032 14.6 7.0 23 5.5 0.1 4.9 5 0 0 5 5 5 0 Putative 2OG-Fe(II) oxygenase RVT_1 PF00078.27 KKA00966.1 - 2.3e-31 109.0 0.2 5.1e-31 107.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KKA00966.1 - 5.7e-28 96.9 0.0 2.2e-27 95.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKA00966.1 - 4.8e-26 91.1 0.0 2.9e-25 88.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_A2B PF12384.8 KKA00966.1 - 1.7e-11 44.0 0.1 3.7e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Integrase_H2C2 PF17921.1 KKA00966.1 - 1.6e-10 40.9 0.2 4.7e-10 39.4 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KKA00966.1 - 1.4e-09 38.2 0.1 2.8e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KKA00966.1 - 1.7e-05 25.3 0.2 5.3e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKA00966.1 - 3.9e-05 24.2 0.2 0.00014 22.4 0.1 2.0 2 0 0 2 2 1 1 Aspartyl protease DUF1758 PF05585.12 KKA00966.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 KKA00966.1 - 0.014 15.6 0.2 0.059 13.6 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RVP PF00077.20 KKA00966.1 - 0.039 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 KKA00966.1 - 0.049 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 KKA00966.1 - 0.9 9.4 4.5 0.24 11.2 0.5 2.1 2 0 0 2 2 2 0 Integrase core domain Oxidored_FMN PF00724.20 KKA00967.1 - 4.1e-87 292.6 0.0 1.2e-78 264.8 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sld5 PF05916.11 KKA00967.1 - 0.13 12.7 0.0 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 GINS complex protein RVT_1 PF00078.27 KKA00968.1 - 2.3e-31 109.0 0.2 5.2e-31 107.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KKA00968.1 - 5.6e-28 96.9 0.0 2.2e-27 95.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKA00968.1 - 4.9e-26 91.1 0.0 3e-25 88.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_A2B PF12384.8 KKA00968.1 - 2.2e-11 43.6 0.1 4.9e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Integrase_H2C2 PF17921.1 KKA00968.1 - 1.6e-10 40.9 0.2 4.8e-10 39.4 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KKA00968.1 - 1.4e-09 38.1 0.1 2.8e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KKA00968.1 - 1.8e-05 25.2 0.2 5.6e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKA00968.1 - 3e-05 24.6 0.2 0.00011 22.8 0.1 2.0 2 0 0 2 2 1 1 Aspartyl protease DUF1758 PF05585.12 KKA00968.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 KKA00968.1 - 0.015 15.5 0.2 0.061 13.6 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RVP_2 PF08284.11 KKA00968.1 - 0.026 14.3 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 KKA00968.1 - 0.037 14.3 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 KKA00968.1 - 0.99 9.2 4.5 0.24 11.2 0.5 2.1 2 0 0 2 2 2 0 Integrase core domain Helicase_C PF00271.31 KKA00969.1 - 9.2e-30 103.3 0.2 1.5e-29 102.6 0.2 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_L14 PF00238.19 KKA00970.1 - 7.1e-29 100.4 1.7 7.8e-29 100.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 KKA00971.1 - 1e-36 126.7 2.3 1.8e-31 109.5 0.1 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA00971.1 - 2.4e-15 56.6 0.0 5.5e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA00971.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKA00971.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHC PF00098.23 KKA00972.1 - 3.4e-05 23.7 1.7 3.4e-05 23.7 1.7 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 KKA00972.1 - 0.00011 21.9 2.2 0.00017 21.3 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KKA00972.1 - 0.0041 16.8 2.8 0.0053 16.4 1.3 1.9 1 1 0 1 1 1 1 C2H2 zinc-finger DUF601 PF04642.12 KKA00973.1 - 0.0082 15.7 3.1 0.0093 15.5 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF601 APS_kinase PF01583.20 KKA00974.1 - 6.3e-05 22.9 0.0 8.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KKA00974.1 - 6.7e-05 23.4 0.1 0.00019 22.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KKA00974.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KKA00974.1 - 0.03 14.5 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKA00974.1 - 0.034 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KKA00974.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KKA00974.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ploopntkinase2 PF18747.1 KKA00974.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 AAA_30 PF13604.6 KKA00974.1 - 0.12 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKA00974.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKA00974.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain tRNA-synt_1 PF00133.22 KKA00975.1 - 1.3e-138 462.9 7.0 2e-138 462.3 7.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKA00975.1 - 8.9e-19 67.5 8.0 5.9e-08 31.9 2.7 4.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKA00975.1 - 3.5e-12 46.5 0.1 9.7e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA CENP-H PF05837.12 KKA00975.1 - 0.66 10.4 5.1 1.5 9.3 0.5 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Oxidored_FMN PF00724.20 KKA00976.1 - 4.1e-87 292.6 0.0 1.2e-78 264.8 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sld5 PF05916.11 KKA00976.1 - 0.13 12.7 0.0 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 GINS complex protein Sugar_tr PF00083.24 KKA00977.1 - 1.5e-63 215.2 19.5 1.7e-63 215.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KKA00978.1 - 4.8e-10 38.9 5.1 6.9e-10 38.4 5.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA00978.1 - 6.6e-08 31.9 2.8 8.7e-08 31.5 2.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KKA00978.1 - 0.0048 15.5 1.8 0.006 15.2 1.8 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Rhomboid PF01694.22 KKA00978.1 - 0.062 13.3 0.8 1.4 8.9 0.1 2.0 1 1 1 2 2 2 0 Rhomboid family Flocculin PF00624.18 KKA00979.1 - 4.1e-119 388.6 673.6 2.7e-10 40.3 30.7 22.8 21 3 2 23 23 23 15 Flocculin repeat zf-C2H2 PF00096.26 KKA00980.1 - 4.2e-12 45.8 9.2 1.6e-05 25.0 2.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKA00980.1 - 1.6e-09 37.8 6.0 0.00058 20.5 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KKA00980.1 - 7.4e-06 26.2 1.7 0.044 14.2 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKA00980.1 - 2.1e-05 24.6 1.1 0.06 13.6 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKA00980.1 - 0.00015 21.4 3.3 0.0062 16.3 0.3 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KKA00980.1 - 0.0074 16.3 3.7 1 9.5 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKA00980.1 - 0.008 16.6 13.6 0.025 15.0 2.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-BED PF02892.15 KKA00980.1 - 0.041 13.9 1.3 0.041 13.9 1.3 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_aberr PF17017.5 KKA00980.1 - 0.059 13.5 1.6 0.23 11.6 0.4 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KKA00980.1 - 0.88 9.4 8.0 1.3 8.9 4.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf_ZIC PF18366.1 KKA00980.1 - 1.4 9.1 4.0 18 5.5 0.3 2.4 2 0 0 2 2 2 0 Zic proteins zinc finger domain ARS2 PF04959.13 KKA00980.1 - 2.6 8.4 5.5 8.5 6.7 0.2 3.3 2 1 1 3 3 3 0 Arsenite-resistance protein 2 AAA_18 PF13238.6 KKA00981.1 - 5.4e-26 91.7 1.3 7.6e-26 91.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKA00981.1 - 3.2e-05 24.2 0.0 0.00025 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 KKA00981.1 - 0.00018 21.5 1.2 0.11 12.3 0.0 2.9 2 1 1 3 3 3 1 Deoxynucleoside kinase AAA_17 PF13207.6 KKA00981.1 - 0.00045 20.7 1.7 0.00078 19.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain Rad17 PF03215.15 KKA00981.1 - 0.00064 19.7 0.6 0.0011 18.9 0.1 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KKA00981.1 - 0.00067 20.0 0.1 0.0056 17.1 0.0 2.3 1 1 1 2 2 2 1 RNA helicase AAA_33 PF13671.6 KKA00981.1 - 0.0017 18.5 0.3 0.13 12.4 0.0 3.0 1 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KKA00981.1 - 0.0019 18.2 0.0 0.0049 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKA00981.1 - 0.0022 18.4 0.0 0.0034 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKA00981.1 - 0.0035 17.6 0.1 0.0072 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KKA00981.1 - 0.0043 16.4 0.8 0.044 13.1 0.1 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.6 KKA00981.1 - 0.0049 16.9 0.7 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KKA00981.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MCM PF00493.23 KKA00981.1 - 0.006 15.7 0.1 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activ_2 PF14532.6 KKA00981.1 - 0.0091 16.1 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain KTI12 PF08433.10 KKA00981.1 - 0.0092 15.5 1.2 0.022 14.2 0.0 2.2 3 0 0 3 3 2 1 Chromatin associated protein KTI12 AAA PF00004.29 KKA00981.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KKA00981.1 - 0.013 14.7 1.2 0.018 14.3 1.2 1.6 1 1 0 1 1 1 0 G-protein alpha subunit NTPase_1 PF03266.15 KKA00981.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 KKA00981.1 - 0.02 14.3 0.1 0.054 12.9 0.0 1.6 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KKA00981.1 - 0.021 14.6 1.6 0.043 13.5 1.6 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKA00981.1 - 0.022 15.3 1.4 0.04 14.4 1.1 1.9 1 1 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KKA00981.1 - 0.025 14.3 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KKA00981.1 - 0.026 13.8 0.1 0.07 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 KKA00981.1 - 0.031 13.4 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GvpD PF07088.11 KKA00981.1 - 0.033 12.8 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein THP2 PF09432.10 KKA00981.1 - 0.039 14.0 3.4 0.1 12.6 3.4 1.7 1 0 0 1 1 1 0 Tho complex subunit THP2 T2SSE PF00437.20 KKA00981.1 - 0.041 13.0 0.2 0.073 12.1 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KKA00981.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KKA00981.1 - 0.072 13.2 1.1 0.32 11.1 1.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKA00981.1 - 0.079 12.9 0.7 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 KKA00981.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ADK PF00406.22 KKA00981.1 - 0.9 9.6 3.1 18 5.4 0.0 2.9 3 0 0 3 3 3 0 Adenylate kinase NusA_N PF08529.11 KKA00981.1 - 3.1 8.2 8.2 2.8 8.3 2.0 2.7 2 1 0 3 3 3 0 NusA N-terminal domain zf-RanBP PF00641.18 KKA00982.1 - 5.3e-08 32.0 3.9 1.2e-07 30.9 3.9 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KKA00982.1 - 0.017 14.9 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.12 KKA00983.1 - 3.6e-23 81.5 0.3 7.1e-23 80.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKA00983.1 - 1.3e-17 64.0 0.3 2.9e-17 62.8 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKA00983.1 - 0.00035 20.1 0.5 0.0035 16.9 0.5 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KKA00983.1 - 0.00037 19.9 0.1 0.00064 19.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKA00983.1 - 0.022 15.0 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KKA00983.1 - 0.033 13.5 0.5 0.058 12.7 0.5 1.3 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.17 KKA00983.1 - 0.047 14.3 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Prefoldin_2 PF01920.20 KKA00984.1 - 4.6e-16 58.7 13.5 4.6e-16 58.7 13.5 1.6 1 1 0 1 1 1 1 Prefoldin subunit ATP-synt_B PF00430.18 KKA00984.1 - 0.00071 19.7 0.9 0.00071 19.7 0.9 2.0 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) Syntaxin-6_N PF09177.11 KKA00984.1 - 0.0048 17.4 4.6 0.0064 17.0 4.6 1.1 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Prefoldin PF02996.17 KKA00984.1 - 0.062 13.2 15.3 9.8 6.1 15.2 2.5 1 1 0 1 1 1 0 Prefoldin subunit Prefoldin_3 PF13758.6 KKA00984.1 - 0.073 13.1 6.8 0.12 12.5 0.1 2.6 3 0 0 3 3 3 0 Prefoldin subunit Ntox28 PF15605.6 KKA00984.1 - 0.38 11.0 7.6 0.82 9.9 0.5 2.1 2 0 0 2 2 2 0 Bacterial toxin 28 SKA1 PF07160.12 KKA00984.1 - 0.48 10.2 16.1 0.1 12.4 6.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ORF6C PF10552.9 KKA00984.1 - 1.8 8.7 13.1 0.14 12.3 4.4 2.3 1 1 1 2 2 2 0 ORF6C domain ERM PF00769.19 KKA00984.1 - 2.7 7.8 19.5 0.55 10.0 8.2 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PTS_IIA PF02255.16 KKA00984.1 - 2.7 8.1 10.1 0.39 10.8 4.6 2.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Snapin_Pallidin PF14712.6 KKA00984.1 - 2.7 8.5 18.1 6.3 7.3 7.6 2.9 1 1 1 2 2 2 0 Snapin/Pallidin cwf21 PF08312.12 KKA00984.1 - 3.1 8.0 10.2 5.1 7.3 3.9 2.4 2 0 0 2 2 2 0 cwf21 domain Tweety PF04906.13 KKA00984.1 - 4 6.0 6.1 0.85 8.2 2.3 1.7 1 1 0 1 1 1 0 Tweety LMBR1 PF04791.16 KKA00984.1 - 4.9 5.9 6.5 5.4 5.8 6.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KKA00984.1 - 5 7.7 18.8 6.3 7.3 7.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Rpn3_C PF08375.11 KKA00984.1 - 5.9 7.4 8.5 0.48 10.9 3.1 1.9 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal YMF19 PF02326.15 KKA00984.1 - 6.7 7.6 6.5 3.6 8.4 2.5 2.0 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF1788 PF08747.11 KKA00984.1 - 7.1 6.7 8.2 9.1 6.3 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) POC1 PF10450.9 KKA00985.1 - 4.9e-11 42.1 1.6 6.8e-11 41.7 1.6 1.5 1 1 0 1 1 1 1 POC1 chaperone MFS_1 PF07690.16 KKA00986.1 - 1.7e-10 40.4 14.4 2.8e-10 39.7 14.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.20 KKA00987.1 - 3.7e-39 134.0 0.1 6.1e-39 133.3 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKA00987.1 - 3.5e-12 46.3 1.1 3.5e-12 46.3 1.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKA00987.1 - 9.1e-05 22.6 0.1 0.00018 21.7 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SIP1 PF04938.12 KKA00987.1 - 0.068 12.9 0.6 0.096 12.4 0.6 1.4 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Oxidored_FMN PF00724.20 KKA00988.1 - 1.1e-44 153.1 0.5 7.5e-39 133.9 0.1 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DIE2_ALG10 PF04922.12 KKA00989.1 - 3.5e-30 105.6 38.6 3.5e-30 105.6 38.6 2.3 2 1 0 2 2 2 1 DIE2/ALG10 family Flocculin PF00624.18 KKA00990.1 - 2.5e-13 50.0 167.1 9.6e-06 25.8 21.6 16.5 13 3 1 14 14 14 9 Flocculin repeat GLEYA PF10528.9 KKA00991.1 - 9e-23 80.5 0.3 2.3e-22 79.2 0.3 1.7 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KKA00991.1 - 9.2e-08 32.0 0.0 4.1e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 PA14 domain IL17R_fnIII_D1 PF16556.5 KKA00991.1 - 0.051 13.2 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 DUF805 PF05656.14 KKA00992.1 - 1.1 9.8 5.7 0.89 10.0 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) TRP PF06011.12 KKA00993.1 - 1.3e-141 472.2 38.2 1.9e-141 471.7 38.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKA00993.1 - 1.2e-38 132.6 0.1 2e-38 131.9 0.1 1.4 1 0 0 1 1 1 1 ML-like domain BPL_N PF09825.9 KKA00995.1 - 1e-76 258.5 0.0 1.3e-76 258.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KKA00995.1 - 2.7e-08 33.8 0.0 6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 KKA00995.1 - 8.7e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CDP-OH_P_transf PF01066.21 KKA00996.1 - 1.8e-15 57.5 0.6 1.8e-15 57.5 0.6 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UNC45-central PF11701.8 KKA00996.1 - 0.039 13.9 0.3 0.074 13.0 0.3 1.7 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Cpn60_TCP1 PF00118.24 KKA00997.1 - 3.8e-134 448.0 17.6 2.5e-133 445.3 17.6 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Asp PF00026.23 KKA00998.1 - 1.8e-45 155.7 18.0 4.4e-45 154.4 18.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKA00998.1 - 1.6e-08 35.0 4.8 2.8e-07 31.0 0.8 3.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKA00998.1 - 0.0041 17.7 0.1 4.1 8.1 0.0 3.8 4 1 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 KKA00998.1 - 0.0046 17.5 0.5 0.63 10.6 0.0 3.6 3 2 1 4 4 4 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKA00998.1 - 0.033 14.0 0.7 0.76 9.5 0.2 2.7 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal PAP1 PF08601.10 KKA00999.1 - 4.3e-18 66.2 5.7 4.3e-18 66.2 5.7 3.0 1 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KKA00999.1 - 4.2e-10 39.6 15.8 1.2e-09 38.1 15.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKA00999.1 - 1.8e-05 24.7 15.1 1.8e-05 24.7 15.1 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKA00999.1 - 0.016 15.7 8.0 0.041 14.4 8.0 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Syntaxin-6_N PF09177.11 KKA00999.1 - 0.04 14.5 6.1 0.049 14.2 4.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal UPF0449 PF15136.6 KKA00999.1 - 1.6 9.3 11.1 0.3 11.6 6.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF737 PF05300.11 KKA00999.1 - 1.8 8.9 10.5 3.7 7.8 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3337 PF11816.8 KKA01001.1 - 0.092 12.6 0.9 0.13 12.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) PAP1 PF08601.10 KKA01003.1 - 4.3e-18 66.2 5.7 4.3e-18 66.2 5.7 3.0 1 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KKA01003.1 - 4.2e-10 39.6 15.8 1.2e-09 38.1 15.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKA01003.1 - 1.8e-05 24.7 15.1 1.8e-05 24.7 15.1 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKA01003.1 - 0.016 15.7 8.0 0.041 14.4 8.0 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Syntaxin-6_N PF09177.11 KKA01003.1 - 0.04 14.5 6.1 0.049 14.2 4.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal UPF0449 PF15136.6 KKA01003.1 - 1.6 9.3 11.1 0.3 11.6 6.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF737 PF05300.11 KKA01003.1 - 1.8 8.9 10.5 3.7 7.8 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3337 PF11816.8 KKA01005.1 - 0.092 12.6 0.9 0.13 12.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) IMS PF00817.20 KKA01007.1 - 1.3e-36 125.9 0.0 2.5e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KKA01007.1 - 6.6e-06 25.6 0.6 1.3e-05 24.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KKA01007.1 - 0.08 13.3 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 IMS family HHH motif Ribosomal_L11_N PF03946.14 KKA01008.1 - 7e-21 73.8 1.5 1.3e-20 72.9 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KKA01008.1 - 5.9e-16 58.7 0.8 1.1e-15 57.8 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SpoVIF PF14069.6 KKA01008.1 - 0.019 14.7 0.8 0.019 14.7 0.8 1.8 2 0 0 2 2 2 0 Stage VI sporulation protein F TAF8_C PF10406.9 KKA01009.1 - 0.0048 17.4 1.0 0.0048 17.4 1.0 2.6 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term DUF2206 PF09971.9 KKA01009.1 - 0.029 13.1 1.7 0.048 12.4 1.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) NIF PF03031.18 KKA01010.1 - 3.1e-22 79.0 0.6 8.8e-22 77.5 0.6 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KKA01010.1 - 0.083 13.3 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.6 KKA01010.1 - 0.13 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like CTU2 PF10288.9 KKA01010.1 - 0.37 11.1 2.6 0.23 11.7 0.3 1.9 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Cwf_Cwc_15 PF04889.12 KKA01010.1 - 0.91 9.2 16.2 0.44 10.2 6.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PGM_PMM_I PF02878.16 KKA01011.1 - 6.4e-39 132.8 0.1 1.2e-38 131.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KKA01011.1 - 4.1e-22 78.8 0.1 1.5e-21 77.0 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKA01011.1 - 3.3e-18 66.0 0.0 6.6e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RVT_1 PF00078.27 KKA01012.1 - 2.2e-31 109.1 0.2 4.3e-31 108.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KKA01012.1 - 1e-27 96.1 0.0 2.7e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKA01012.1 - 8.9e-26 90.2 0.0 2.7e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KKA01012.1 - 1.2e-10 41.3 0.2 3.8e-10 39.7 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KKA01012.1 - 1.1e-09 38.5 0.1 2.2e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KKA01012.1 - 0.011 16.0 0.2 0.049 13.9 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger rve_3 PF13683.6 KKA01012.1 - 0.66 9.8 4.5 0.19 11.5 0.5 2.2 2 0 0 2 2 2 0 Integrase core domain Snf7 PF03357.21 KKA01013.1 - 2.2e-11 43.7 25.5 2.2e-11 43.7 25.5 2.1 1 1 1 2 2 2 1 Snf7 Effector_1 PF04518.12 KKA01013.1 - 1.6 7.7 19.5 0.007 15.5 8.3 1.9 1 1 1 2 2 2 0 Effector from type III secretion system Opi1 PF08618.10 KKA01014.1 - 1.1e-13 51.3 6.8 5.5e-06 25.9 0.4 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 Suf PF05843.14 KKA01015.1 - 0.0031 17.6 0.2 0.0031 17.6 0.2 3.4 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) Glyco_hydro_28 PF00295.17 KKA01015.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 CLAMP PF14769.6 KKA01015.1 - 0.18 12.3 3.8 3.1 8.3 0.2 3.7 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 zf-CCHC PF00098.23 KKA01016.1 - 5.5e-05 23.1 1.7 5.5e-05 23.1 1.7 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 KKA01016.1 - 0.00045 20.0 2.1 0.00067 19.4 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KKA01016.1 - 0.011 15.5 1.0 0.018 14.7 1.0 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger SET PF00856.28 KKA01017.1 - 0.00025 21.5 0.5 0.00074 20.0 0.5 1.8 1 0 0 1 1 1 1 SET domain SMC_N PF02463.19 KKA01017.1 - 0.012 15.1 0.3 0.018 14.5 0.3 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MitMem_reg PF13012.6 KKA01017.1 - 1.3 9.5 4.3 1 9.8 1.5 2.3 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Gly_transf_sug PF04488.15 KKA01018.1 - 2.2e-14 53.9 0.4 2.7e-13 50.4 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3654 PF12376.8 KKA01018.1 - 0.0063 16.7 2.1 0.013 15.7 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3654) Fzo_mitofusin PF04799.13 KKA01018.1 - 0.028 14.0 1.3 0.052 13.1 1.3 1.5 1 0 0 1 1 1 0 fzo-like conserved region Mog1 PF04603.12 KKA01019.1 - 3.5e-28 98.7 0.3 8.4e-28 97.5 0.3 1.6 1 1 0 1 1 1 1 Ran-interacting Mog1 protein RabGAP-TBC PF00566.18 KKA01020.1 - 1.1e-46 159.2 5.5 1.1e-46 159.2 5.5 2.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF5363 PF17320.2 KKA01020.1 - 0.068 13.1 0.5 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5363) HTH_Tnp_1 PF01527.20 KKA01020.1 - 0.63 10.4 2.4 2.3 8.6 1.9 2.3 2 1 0 2 2 2 0 Transposase V-SNARE_C PF12352.8 KKA01021.1 - 1.3e-10 41.4 3.7 1.3e-10 41.4 3.7 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF3675 PF12428.8 KKA01021.1 - 0.016 15.8 0.2 0.039 14.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Sec20 PF03908.13 KKA01021.1 - 0.051 13.5 10.3 0.043 13.7 3.7 2.7 1 1 1 3 3 3 0 Sec20 YqjK PF13997.6 KKA01021.1 - 0.21 11.9 0.8 0.39 11.0 0.0 2.0 3 0 0 3 3 3 0 YqjK-like protein TBCA PF02970.16 KKA01021.1 - 0.5 10.7 6.3 2.1 8.7 0.1 3.0 1 1 2 3 3 3 0 Tubulin binding cofactor A Glyco_hydro_15 PF00723.21 KKA01022.1 - 4.5e-45 154.3 0.0 7.9e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RGS PF00615.19 KKA01022.1 - 0.02 15.2 0.3 0.062 13.6 0.3 1.8 1 0 0 1 1 1 0 Regulator of G protein signaling domain DUF496 PF04363.12 KKA01022.1 - 0.1 12.7 0.5 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Fer2 PF00111.27 KKA01023.1 - 4.9e-13 48.8 1.0 6.4e-13 48.5 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain AAA_2 PF07724.14 KKA01024.1 - 6.7e-35 120.7 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KKA01024.1 - 1.3e-13 51.5 0.0 4.4e-13 49.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKA01024.1 - 3.2e-08 33.5 0.0 1.1e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKA01024.1 - 8.9e-06 25.7 0.0 3.3e-05 23.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKA01024.1 - 6.7e-05 23.2 0.2 0.0012 19.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain MCM PF00493.23 KKA01024.1 - 0.00025 20.2 0.3 0.00045 19.4 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KKA01024.1 - 0.00041 19.8 0.0 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KKA01024.1 - 0.00082 19.4 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KKA01024.1 - 0.0036 17.8 0.1 0.0097 16.4 0.1 1.9 1 0 0 1 1 1 1 ABC transporter TsaE PF02367.17 KKA01024.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KKA01024.1 - 0.0051 16.6 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKA01024.1 - 0.0051 16.6 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KKA01024.1 - 0.0067 16.2 0.8 0.021 14.6 0.2 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKA01024.1 - 0.007 16.9 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KKA01024.1 - 0.0089 15.8 0.1 4.7 7.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KKA01024.1 - 0.0093 16.4 0.0 0.024 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KKA01024.1 - 0.012 15.2 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KKA01024.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKA01024.1 - 0.045 14.1 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 KKA01024.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KKA01024.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 KKA01024.1 - 0.081 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 KKA01024.1 - 0.086 12.5 0.0 0.82 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 KKA01024.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KKA01024.1 - 0.099 12.6 0.1 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KKA01024.1 - 0.11 12.9 0.2 0.54 10.6 0.1 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KKA01024.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain MTHFR PF02219.17 KKA01025.1 - 1.5e-99 332.9 0.0 3.2e-99 331.9 0.0 1.5 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Radical_SAM PF04055.21 KKA01025.1 - 0.14 12.6 0.0 37 4.7 0.0 3.5 2 1 0 2 2 2 0 Radical SAM superfamily Flocculin PF00624.18 KKA01026.1 - 1.2e-148 483.2 466.4 3e-09 37.0 9.8 22.4 21 1 1 22 22 22 21 Flocculin repeat Pab87_oct PF13969.6 KKA01026.1 - 0.0012 18.9 0.1 33 4.6 0.0 3.7 3 0 0 3 3 3 3 Pab87 octamerisation domain DUF5091 PF17012.5 KKA01026.1 - 0.17 12.1 2.4 98 3.2 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5091) 2OG-FeII_Oxy_5 PF13759.6 KKA01026.1 - 4.6 7.7 24.2 76 3.8 0.1 8.3 10 0 0 10 10 10 0 Putative 2OG-Fe(II) oxygenase SET PF00856.28 KKA01028.1 - 0.00025 21.5 0.5 0.00074 20.0 0.5 1.8 1 0 0 1 1 1 1 SET domain SMC_N PF02463.19 KKA01028.1 - 0.012 15.1 0.3 0.018 14.5 0.3 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MitMem_reg PF13012.6 KKA01028.1 - 1.3 9.5 4.3 1 9.8 1.5 2.3 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Gly_transf_sug PF04488.15 KKA01029.1 - 2.2e-14 53.9 0.4 2.7e-13 50.4 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3654 PF12376.8 KKA01029.1 - 0.0063 16.7 2.1 0.013 15.7 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3654) Fzo_mitofusin PF04799.13 KKA01029.1 - 0.028 14.0 1.3 0.052 13.1 1.3 1.5 1 0 0 1 1 1 0 fzo-like conserved region Mog1 PF04603.12 KKA01030.1 - 3.5e-28 98.7 0.3 8.4e-28 97.5 0.3 1.6 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Pinin_SDK_memA PF04696.13 KKA01032.1 - 3.3 7.8 10.4 0.26 11.3 1.0 2.8 2 1 1 3 3 3 0 pinin/SDK/memA/ protein conserved region LCAT PF02450.15 KKA01033.1 - 4e-105 352.2 0.0 5.2e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Cag12 PF13117.6 KKA01033.1 - 0.026 15.0 2.1 0.18 12.4 0.3 2.5 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 DUF4708 PF15813.5 KKA01033.1 - 0.053 12.7 0.1 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) DUF1749 PF08538.10 KKA01033.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKA01033.1 - 0.086 13.4 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKA01033.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Autophagy_N PF03986.13 KKA01034.1 - 5.5e-33 113.8 0.8 9.1e-33 113.1 0.8 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KKA01034.1 - 7.8e-16 58.4 0.1 1.5e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KKA01034.1 - 5e-14 51.5 4.0 1e-13 50.5 4.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal FYVE PF01363.21 KKA01035.1 - 7.7e-18 64.4 5.0 1.5e-17 63.5 5.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KKA01035.1 - 0.00013 21.7 2.4 0.0074 16.1 0.2 3.8 3 0 0 3 3 3 1 Ubiquitin interaction motif VHS PF00790.19 KKA01035.1 - 0.046 13.6 3.4 0.18 11.7 0.1 2.9 2 1 0 2 2 2 0 VHS domain Prominin PF05478.11 KKA01035.1 - 0.28 9.1 7.3 0.5 8.2 7.3 1.3 1 0 0 1 1 1 0 Prominin zf-AN1 PF01428.16 KKA01035.1 - 0.58 10.4 8.3 1.4 9.2 8.3 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger SAGA-Tad1 PF12767.7 KKA01037.1 - 1.7e-28 99.9 6.3 1.3e-26 93.8 6.3 3.0 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF2316 PF10078.9 KKA01037.1 - 0.024 14.8 0.1 1.2 9.5 0.0 3.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Ribosomal_S19 PF00203.21 KKA01037.1 - 0.031 14.2 0.6 1.2 9.1 0.0 2.7 2 1 0 2 2 2 0 Ribosomal protein S19 F-box PF00646.33 KKA01038.1 - 0.065 13.1 0.4 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 F-box domain NIF PF03031.18 KKA01039.1 - 1.3e-35 122.5 4.5 4.9e-34 117.3 4.5 2.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Flocculin PF00624.18 KKA01040.1 - 3e-294 949.1 1516.3 3.8e-09 36.7 14.8 67.0 65 1 2 67 67 67 59 Flocculin repeat MAS20 PF02064.15 KKA01041.1 - 2.2e-24 86.0 0.1 3.1e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor DUF2535 PF10751.9 KKA01041.1 - 0.06 13.9 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) IPK PF03770.16 KKA01042.1 - 2.5e-43 148.3 0.9 3.5e-43 147.8 0.9 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GTP_EFTU PF00009.27 KKA01043.1 - 8e-45 152.8 0.0 1.5e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKA01043.1 - 6.6e-33 113.4 1.4 3e-32 111.2 1.4 2.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKA01043.1 - 7.5e-09 35.9 2.1 2.2e-08 34.3 2.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKA01043.1 - 0.0016 18.5 0.2 0.0085 16.2 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 KKA01043.1 - 0.09 13.1 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain Herpes_UL17 PF04559.12 KKA01043.1 - 9.4 4.9 11.0 14 4.4 11.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein UBX PF00789.20 KKA01044.1 - 1.4e-10 41.2 0.1 0.00015 21.9 0.0 2.6 2 0 0 2 2 2 2 UBX domain UBA_4 PF14555.6 KKA01044.1 - 0.0016 18.2 0.2 0.0075 16.1 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain DUF806 PF05657.11 KKA01044.1 - 0.67 10.4 6.1 9 6.8 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF806) Methyltransf_11 PF08241.12 KKA01045.1 - 4.8e-09 36.8 0.0 2e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA01045.1 - 2.5e-08 34.5 0.0 2.4e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKA01045.1 - 3.3e-07 30.2 0.6 1.3e-05 25.1 0.6 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA01045.1 - 1.9e-06 27.8 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA01045.1 - 1.2e-05 26.0 0.0 3.4e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PIG-S PF10510.9 KKA01046.1 - 3.2e-45 155.0 0.8 1.5e-27 96.6 0.2 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Type2_restr_D3 PF16902.5 KKA01046.1 - 0.14 12.1 0.7 6.8 6.7 0.2 2.7 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain E1-E2_ATPase PF00122.20 KKA01047.1 - 2.5e-47 160.7 5.2 4.2e-47 160.0 3.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KKA01047.1 - 3.4e-21 76.5 0.4 1.1e-20 74.8 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKA01047.1 - 4.3e-08 32.7 0.0 9.4e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus UreE_N PF02814.15 KKA01047.1 - 0.0048 16.5 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 UreE urease accessory protein, N-terminal domain Cation_ATPase PF13246.6 KKA01047.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKA01047.1 - 0.026 14.3 0.1 0.026 14.3 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L2_C PF03947.18 KKA01048.1 - 5.1e-48 162.4 2.9 9.4e-48 161.6 2.9 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKA01048.1 - 9.8e-20 70.3 0.7 9.8e-20 70.3 0.7 2.8 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.17 KKA01049.1 - 5.2e-22 78.5 0.0 1.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKA01049.1 - 0.026 14.2 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ATP-synt_D PF01813.17 KKA01050.1 - 6.6e-61 205.6 4.1 6.6e-61 205.6 4.1 1.7 2 0 0 2 2 2 1 ATP synthase subunit D Ribosomal_L6e PF01159.19 KKA01050.1 - 3.8 8.1 15.4 5e+02 1.3 15.4 2.6 1 1 0 1 1 1 0 Ribosomal protein L6e Sod_Fe_C PF02777.18 KKA01051.1 - 5.6e-08 32.9 0.1 4.8e-05 23.5 0.1 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Cauli_AT PF03233.13 KKA01051.1 - 0.00047 20.1 3.1 0.23 11.4 0.8 2.4 2 0 0 2 2 2 2 Aphid transmission protein DarA_N PF18788.1 KKA01051.1 - 0.023 14.8 0.7 0.16 12.0 0.1 2.4 3 1 0 3 3 3 0 Defence against restriction A N-terminal Sod_Fe_N PF00081.22 KKA01051.1 - 0.076 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2019 PF09450.10 KKA01051.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Ferric_reduct PF01794.19 KKA01052.1 - 5e-21 75.1 16.0 5e-21 75.1 16.0 2.3 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKA01052.1 - 4.3e-17 62.2 0.0 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KKA01052.1 - 5e-07 30.0 1.6 1.2e-06 28.7 1.6 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NDUF_B7 PF05676.13 KKA01052.1 - 0.0076 15.9 2.3 0.02 14.6 2.3 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ferric_reduct PF01794.19 KKA01053.1 - 1.6e-23 83.2 12.1 1.6e-23 83.2 12.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKA01053.1 - 3.4e-17 62.5 0.1 9.9e-17 61.0 0.1 1.8 1 0 0 1 1 1 1 FAD-binding domain MMR_HSR1_C PF08438.10 KKA01054.1 - 4.7e-30 104.4 0.0 7.8e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KKA01054.1 - 5.1e-20 71.7 0.0 1.3e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKA01054.1 - 6.1e-10 38.8 0.4 5.1e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKA01054.1 - 0.00092 19.2 0.3 1.7 8.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KKA01054.1 - 0.008 15.5 0.1 0.018 14.4 0.1 1.7 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KKA01054.1 - 0.038 14.0 0.6 0.15 12.1 0.1 2.2 3 0 0 3 3 3 0 Dynamin family Orf78 PF06024.12 KKA01054.1 - 0.065 13.5 0.1 4.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Vac17 PF17321.2 KKA01055.1 - 4.1e-09 36.4 30.0 1.3e-08 34.7 29.2 2.1 1 1 0 1 1 1 1 Vacuole-related protein 17 KH_8 PF17903.1 KKA01057.1 - 1.8e-30 104.8 0.0 3.8e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKA01057.1 - 0.022 14.6 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 KH domain Myb_DNA-bind_3 PF12776.7 KKA01059.1 - 0.0019 19.1 1.1 0.0019 19.1 1.1 2.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KKA01059.1 - 0.0079 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KKA01059.1 - 0.024 14.7 2.9 0.046 13.8 0.8 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_L11_N PF03946.14 KKA01059.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Chorismate_bind PF00425.18 KKA01059.1 - 0.17 11.4 0.8 0.28 10.7 0.8 1.3 1 1 0 1 1 1 0 chorismate binding enzyme Myb_DNA-bind_4 PF13837.6 KKA01059.1 - 0.34 11.3 8.4 0.045 14.1 2.7 2.2 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MT-A70 PF05063.14 KKA01060.1 - 8.8e-10 38.8 0.0 1.3e-07 31.7 0.0 2.3 1 1 1 2 2 2 2 MT-A70 ATE_N PF04376.13 KKA01060.1 - 0.046 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Tho2 PF11262.8 KKA01061.1 - 1.9 7.7 10.4 1.9 7.6 3.2 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 YgaB PF14182.6 KKA01061.1 - 8.8 6.8 17.2 0.33 11.4 1.4 4.0 4 0 0 4 4 4 0 YgaB-like protein BAR_2 PF10455.9 KKA01062.1 - 4.7e-44 150.7 22.7 8.5e-43 146.5 22.4 2.3 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKA01062.1 - 0.0012 18.5 12.7 0.004 16.8 5.4 3.7 2 2 0 2 2 2 1 BAR domain Utp8 PF10395.9 KKA01063.1 - 2.1e-119 400.0 64.8 2.6e-119 399.7 64.8 1.0 1 0 0 1 1 1 1 Utp8 family Peptidase_M16_C PF05193.21 KKA01064.1 - 2.1e-17 63.7 0.7 8.9e-14 51.9 0.3 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKA01064.1 - 4.6e-10 39.7 2.2 2e-08 34.4 0.0 3.7 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) MitMem_reg PF13012.6 KKA01064.1 - 0.0078 16.6 0.1 0.11 13.0 0.0 2.9 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function Sulfate_transp PF00916.20 KKA01065.1 - 2.5e-67 227.3 18.6 4.1e-67 226.6 18.6 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKA01065.1 - 6.8e-11 41.8 1.8 1.6e-10 40.7 1.8 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KKA01065.1 - 0.032 14.6 13.2 0.021 15.2 3.8 3.4 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily cNMP_binding PF00027.29 KKA01065.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Asn_synthase PF00733.21 KKA01066.1 - 3.7e-95 319.6 0.3 1.1e-53 183.2 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KKA01066.1 - 6.4e-34 116.5 0.0 9.9e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKA01066.1 - 1e-27 97.0 0.0 1.8e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKA01066.1 - 1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KKA01066.1 - 0.0088 15.2 0.0 0.017 14.3 0.0 1.5 1 1 0 1 1 1 1 NAD synthase PIR PF00399.19 KKA01067.1 - 3.4e-56 185.7 100.4 1.7e-08 33.8 4.4 7.9 7 0 0 7 7 7 7 Yeast PIR protein repeat TFIIA PF03153.13 KKA01067.1 - 0.15 12.0 27.1 0.19 11.7 27.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KKA01067.1 - 1.1 7.7 23.1 1.5 7.3 23.1 1.3 1 0 0 1 1 1 0 Macoilin family Rot1 PF10681.9 KKA01068.1 - 9.1e-84 280.2 0.2 1.2e-83 279.8 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Cyclin_N PF00134.23 KKA01069.1 - 4.3e-22 78.2 2.8 4.5e-22 78.1 0.7 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKA01069.1 - 0.23 11.6 1.7 1 9.5 0.0 3.0 3 1 0 3 3 3 0 Cyclin, C-terminal domain p47_phox_C PF08944.11 KKA01069.1 - 0.56 9.7 3.4 0.28 10.6 0.5 2.0 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain FKBP_C PF00254.28 KKA01070.1 - 1.7e-32 111.6 0.0 2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase S4 PF01479.25 KKA01072.1 - 2e-12 46.6 0.3 4.1e-12 45.6 0.3 1.6 1 0 0 1 1 1 1 S4 domain Apo-CIII PF05778.12 KKA01072.1 - 0.06 13.0 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) IML1 PF12257.8 KKA01072.1 - 4.4 6.3 6.4 0.64 9.1 0.8 2.2 2 1 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 CAP_N PF01213.19 KKA01073.1 - 2.5e-87 293.3 6.2 2.5e-87 293.3 6.2 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KKA01073.1 - 6.1e-55 185.1 1.2 8e-55 184.8 0.4 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal HNF_C PF09354.10 KKA01073.1 - 0.0043 18.1 0.0 18 6.5 0.0 3.4 3 0 0 3 3 3 2 HNF3 C-terminal domain TBCC PF07986.12 KKA01073.1 - 0.014 15.1 2.9 0.028 14.2 2.9 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C SF3b10 PF07189.11 KKA01074.1 - 0.017 15.3 0.2 0.027 14.6 0.2 1.4 1 1 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) DUF727 PF05303.12 KKA01074.1 - 0.19 11.8 5.4 0.12 12.5 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF727) STN1_2 PF09170.10 KKA01074.1 - 0.2 11.8 6.5 0.28 11.4 6.5 1.3 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 PRP1_N PF06424.12 KKA01074.1 - 3 8.2 7.1 0.82 10.1 1.6 2.0 1 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Thoc2 PF11732.8 KKA01075.1 - 2.9e-12 46.4 3.5 4.9e-11 42.5 0.2 3.9 4 0 0 4 4 4 1 Transcription- and export-related complex subunit Tho2 PF11262.8 KKA01075.1 - 7.6e-07 28.6 7.1 7.6e-07 28.6 7.1 4.4 4 1 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 C2 PF00168.30 KKA01076.1 - 1.8e-10 41.0 0.0 3.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain RNA_pol_3_Rpc31 PF11705.8 KKA01077.1 - 2.9e-15 57.2 41.1 4.3e-12 46.8 41.1 3.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PGA2 PF07543.12 KKA01078.1 - 2e-09 37.5 6.6 3.6e-09 36.7 6.6 1.3 1 0 0 1 1 1 1 Protein trafficking PGA2 BRX_assoc PF16627.5 KKA01078.1 - 0.056 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Unstructured region between BRX_N and BRX domain EVI2A PF05399.11 KKA01078.1 - 0.067 12.8 1.3 0.077 12.6 0.8 1.4 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3382 PF11862.8 KKA01078.1 - 0.21 11.9 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) UPRTase PF14681.6 KKA01079.1 - 6.7e-69 231.5 0.0 8e-69 231.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKA01079.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain PH PF00169.29 KKA01080.1 - 0.17 12.4 1.8 1.4 9.5 0.1 3.3 2 1 0 3 3 3 0 PH domain Arginase PF00491.21 KKA01081.1 - 1.3e-82 277.5 0.0 1.7e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KKA01081.1 - 0.034 14.4 0.3 0.055 13.7 0.3 1.3 1 0 0 1 1 1 0 UPF0489 domain Arginase PF00491.21 KKA01082.1 - 1.2e-87 294.0 0.0 1.5e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KKA01082.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Sigma_reg_N PF13800.6 KKA01083.1 - 7.6 6.9 8.1 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PIG-X PF08320.12 KKA01084.1 - 4.8e-19 69.1 0.2 9.5e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Bac_chlorC PF02043.17 KKA01085.1 - 2.2 8.3 5.2 2.1 8.4 2.7 2.5 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein UCR_14kD PF02271.16 KKA01086.1 - 1.8e-33 114.4 0.7 2.2e-33 114.2 0.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.9 KKA01087.1 - 1e-10 41.6 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 KKA01087.1 - 4.5e-07 30.5 0.0 9.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 HIT domain DUF4931 PF16285.5 KKA01087.1 - 0.0025 17.1 0.4 0.0067 15.8 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) DcpS_C PF11969.8 KKA01087.1 - 0.011 16.3 0.2 0.022 15.2 0.2 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Imm10 PF15588.6 KKA01087.1 - 0.015 15.4 0.8 3.2 7.9 0.3 2.6 2 0 0 2 2 2 0 Immunity protein 10 DUF4922 PF16269.5 KKA01087.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) Fumble PF03630.14 KKA01088.1 - 2.3e-107 359.0 10.5 3.3e-106 355.2 10.5 2.0 1 1 0 1 1 1 1 Fumble Intimin_C PF07979.11 KKA01088.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Intimin C-type lectin domain PTS_2-RNA PF01885.16 KKA01089.1 - 0.033 14.3 3.5 0.047 13.7 3.5 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family MG1 PF17790.1 KKA01089.1 - 0.075 13.5 5.2 0.22 11.9 5.2 1.8 1 0 0 1 1 1 0 Macroglobulin domain MG1 FIVAR PF07554.13 KKA01089.1 - 8.2 7.3 20.0 7.9 7.3 8.0 4.0 3 1 1 4 4 4 0 FIVAR domain RPAP1_C PF08620.10 KKA01090.1 - 2.9e-24 84.9 0.0 6.2e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KKA01090.1 - 1.6e-12 47.0 7.1 6.1e-12 45.1 7.1 2.0 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pmp3 PF01679.17 KKA01091.1 - 1.2e-05 25.4 11.7 8.8e-05 22.6 11.7 2.0 1 1 0 1 1 1 1 Proteolipid membrane potential modulator Pkinase PF00069.25 KKA01092.1 - 2.1e-51 174.8 0.4 1.4e-49 168.8 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01092.1 - 2.6e-33 115.4 0.0 4.3e-32 111.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKA01092.1 - 5.2e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKA01092.1 - 0.00017 21.0 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Recep_L_domain PF01030.24 KKA01093.1 - 3.9e-07 30.2 16.6 0.0043 17.2 2.7 5.0 1 1 3 4 4 4 2 Receptor L domain GPCR_chapero_1 PF11904.8 KKA01093.1 - 0.0013 18.2 0.3 0.0026 17.2 0.3 1.4 1 0 0 1 1 1 1 GPCR-chaperone LRR_5 PF13306.6 KKA01093.1 - 0.032 14.2 0.7 0.032 14.2 0.7 3.9 1 1 3 4 4 4 0 BspA type Leucine rich repeat region (6 copies) PP-binding_2 PF14573.6 KKA01093.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-carrier LRR_4 PF12799.7 KKA01093.1 - 2.1 8.9 15.9 6.1 7.4 1.0 5.4 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Zn_clus PF00172.18 KKA01094.1 - 8.6e-06 25.8 6.0 1.6e-05 24.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caveolin PF01146.17 KKA01094.1 - 0.44 10.5 2.9 2.8 7.9 0.2 2.6 2 0 0 2 2 2 0 Caveolin FKBP_C PF00254.28 KKA01095.1 - 3e-34 117.2 0.0 4e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EMC1_C PF07774.13 KKA01096.1 - 3.9e-37 128.0 8.1 9.2e-37 126.8 8.1 1.7 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Plasmid_parti PF01672.16 KKA01096.1 - 0.0033 18.0 1.4 0.036 14.7 0.2 3.3 2 0 0 2 2 2 1 Putative plasmid partition protein PQQ PF01011.21 KKA01096.1 - 0.0058 16.5 0.4 0.071 13.1 0.1 3.0 4 0 0 4 4 4 1 PQQ enzyme repeat Mgr1 PF08602.10 KKA01097.1 - 1.4e-80 271.0 0.2 1.7e-80 270.7 0.2 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.20 KKA01098.1 - 6.4e-56 186.7 1.0 1.9e-29 101.6 0.4 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KKA01098.1 - 6.7e-26 91.3 12.1 2.5e-18 66.7 3.6 3.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KKA01098.1 - 3.7e-09 37.0 3.6 3.9e-05 24.1 0.2 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKA01098.1 - 3.2e-07 30.6 1.5 0.11 12.9 0.0 4.6 3 1 1 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 KKA01098.1 - 8.6e-07 28.6 0.3 0.06 12.7 0.0 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KKA01098.1 - 1.1e-06 28.7 0.1 0.039 14.1 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KKA01098.1 - 0.015 15.0 0.5 4 7.1 0.0 3.0 2 1 1 3 3 3 0 Redoxin TraF PF13728.6 KKA01098.1 - 0.032 14.1 0.1 8.9 6.1 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KKA01098.1 - 0.083 13.0 1.9 0.67 10.0 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin domain BACK PF07707.15 KKA01098.1 - 0.19 11.9 1.0 0.51 10.5 0.1 2.2 3 1 0 3 3 3 0 BTB And C-terminal Kelch GRASP55_65 PF04495.14 KKA01099.1 - 1.5e-29 103.0 1.0 2.9e-28 98.9 0.2 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Abhydrolase_1 PF00561.20 KKA01101.1 - 5e-14 52.6 0.0 5.1e-13 49.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA01101.1 - 1.9e-10 40.4 0.0 0.00036 19.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKA01101.1 - 1.3e-09 39.0 0.0 3e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KKA01101.1 - 0.00031 20.4 0.0 0.00086 18.9 0.0 1.8 2 1 0 2 2 2 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KKA01101.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 KKA01101.1 - 0.0036 16.7 2.1 1.2 8.4 0.7 2.5 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KKA01101.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KKA01101.1 - 0.058 13.3 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Pkinase PF00069.25 KKA01102.1 - 6.8e-59 199.4 0.2 6.9e-58 196.1 0.0 2.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01102.1 - 1.3e-35 122.9 0.0 4.6e-35 121.1 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KKA01102.1 - 3.9e-19 68.3 36.1 4.5e-11 42.5 14.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KKA01102.1 - 4.4e-19 68.4 18.2 3.2e-10 40.0 8.3 2.9 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 KKA01102.1 - 1.7e-11 44.6 0.3 7.3e-11 42.6 0.3 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KKA01102.1 - 1.2e-07 32.0 0.1 3.7e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KKA01102.1 - 2.1e-05 24.0 2.9 0.0013 18.2 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Uds1 PF15456.6 KKA01102.1 - 2 8.6 6.8 3.7 7.7 0.1 3.1 2 0 0 2 2 2 0 Up-regulated During Septation AIM24 PF01987.17 KKA01103.1 - 1.2e-12 48.0 0.0 1.8e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Longin PF13774.6 KKA01104.1 - 0.058 13.4 0.1 0.43 10.7 0.1 2.2 2 0 0 2 2 2 0 Regulated-SNARE-like domain IFRD_C PF04836.12 KKA01104.1 - 0.3 11.7 2.1 8.6 7.0 0.3 2.7 2 0 0 2 2 2 0 Interferon-related protein conserved region zinc_ribbon_16 PF17034.5 KKA01105.1 - 1.9e-21 76.6 4.4 1.9e-21 76.6 4.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KKA01105.1 - 0.00038 20.0 10.9 0.00038 20.0 10.9 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type YvbH_ext PF11724.8 KKA01105.1 - 0.0054 17.0 1.7 0.029 14.7 1.7 2.3 1 0 0 1 1 1 1 YvbH-like oligomerisation region DUF2400 PF09674.10 KKA01105.1 - 0.045 13.8 0.7 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Polysacc_syn_2C PF08485.10 KKA01105.1 - 0.072 12.8 0.9 0.26 11.0 0.9 2.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Gln-synt_C PF00120.24 KKA01106.1 - 8.3e-20 71.1 0.0 4.9e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KKA01106.1 - 4.9e-13 48.6 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain tRNA-synt_His PF13393.6 KKA01107.1 - 1e-36 126.8 0.1 1.8e-31 109.6 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KKA01107.1 - 2.9e-09 36.9 0.0 6.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KKA01107.1 - 2.2e-06 27.4 0.1 2.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KKA01107.1 - 0.0033 16.5 0.2 0.011 14.9 0.2 2.0 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) ESCRT-II PF05871.12 KKA01107.1 - 0.015 15.5 0.2 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 ESCRT-II complex subunit Cid2 PF09774.9 KKA01108.1 - 1.9e-25 90.2 0.3 2.5e-25 89.7 0.3 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Lgl_C PF08596.10 KKA01109.1 - 6.6e-88 295.1 2.7 1.5e-87 293.9 2.7 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KKA01109.1 - 6.5e-07 29.6 3.2 0.015 15.6 0.0 6.4 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKA01109.1 - 0.00025 21.8 0.9 2.5 9.1 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat FAM35_C PF15793.5 KKA01109.1 - 0.035 13.5 1.2 0.14 11.5 0.0 2.4 3 0 0 3 3 3 0 Protein family FAM35, C-terminal LVIVD PF08309.11 KKA01109.1 - 0.057 12.7 4.8 1.1 8.6 0.4 3.3 3 0 0 3 3 3 0 LVIVD repeat V-ATPase_H_N PF03224.14 KKA01110.1 - 9.9e-25 87.5 12.8 1.6e-24 86.8 12.8 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KKA01110.1 - 1.8e-24 86.1 6.4 2.6e-24 85.6 0.8 3.1 3 0 0 3 3 3 1 V-ATPase subunit H Citrate_synt PF00285.21 KKA01112.1 - 3.7e-98 328.9 0.0 4.5e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Bmt2 PF11968.8 KKA01113.1 - 2.7e-68 230.1 1.1 3.9e-68 229.6 1.1 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KKA01113.1 - 4.5e-06 26.6 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA01113.1 - 0.049 14.3 0.0 0.14 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KKA01113.1 - 0.059 13.2 0.5 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain Hydrolase PF00702.26 KKA01114.1 - 2.5e-17 63.9 0.3 7.4e-17 62.3 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKA01114.1 - 7.6e-16 59.1 0.0 1.4e-15 58.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKA01114.1 - 1.1e-07 31.9 0.2 1.1e-07 31.9 0.2 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKA01114.1 - 6.3e-06 26.4 3.2 0.048 13.8 0.2 3.0 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKA01114.1 - 0.00032 20.2 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase S6PP PF05116.13 KKA01114.1 - 0.015 14.8 0.1 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_like PF13242.6 KKA01114.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1829 PF08862.10 KKA01114.1 - 0.089 13.3 1.8 0.2 12.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1829 CLASP_N PF12348.8 KKA01115.1 - 5e-05 23.0 4.1 0.0098 15.5 0.0 3.4 3 1 0 3 3 3 1 CLASP N terminal HALZ PF02183.18 KKA01115.1 - 0.0012 19.0 1.2 0.0061 16.8 1.2 2.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper HEAT PF02985.22 KKA01115.1 - 0.0096 16.1 0.0 5.4 7.6 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat DivIC PF04977.15 KKA01115.1 - 0.018 14.8 1.7 0.018 14.8 1.7 2.8 3 0 0 3 3 3 0 Septum formation initiator THUMP PF02926.17 KKA01115.1 - 0.035 14.2 0.6 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 THUMP domain OSTbeta PF15048.6 KKA01115.1 - 0.068 13.3 3.1 0.21 11.7 3.1 1.8 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein MOR2-PAG1_C PF14225.6 KKA01115.1 - 0.2 11.5 3.0 1.9 8.3 0.1 2.6 3 0 0 3 3 3 0 Cell morphogenesis C-terminal TSC22 PF01166.18 KKA01115.1 - 0.21 11.9 4.2 0.43 10.9 1.1 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Bap31_Bap29_C PF18035.1 KKA01115.1 - 0.46 10.5 8.4 3.6 7.7 8.2 2.8 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5344 PF17279.2 KKA01115.1 - 1 10.0 7.5 3.7 8.2 0.2 3.7 3 0 0 3 3 2 0 Family of unknown function (DUF5344) DUF2730 PF10805.8 KKA01115.1 - 2.9 8.0 7.1 5.9 7.0 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) GLEYA PF10528.9 KKA01116.1 - 2.8e-08 34.1 0.0 4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 GLEYA domain Arteri_Gl PF00951.18 KKA01116.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein KASH PF10541.9 KKA01116.1 - 0.024 14.9 1.1 0.12 12.6 0.3 2.2 2 0 0 2 2 2 0 Nuclear envelope localisation domain Mak10 PF04112.13 KKA01119.1 - 2.6e-16 59.6 0.3 7.7e-16 58.1 0.3 1.8 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AFG1_ATPase PF03969.16 KKA01120.1 - 2.1e-79 267.0 0.3 1e-75 254.9 0.0 2.8 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KKA01120.1 - 0.00034 21.1 0.1 0.096 13.1 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKA01120.1 - 0.025 14.8 0.2 0.3 11.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKA01120.1 - 0.085 12.9 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Spem1 PF15670.5 KKA01121.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 KH_6 PF15985.5 KKA01122.1 - 3.7e-10 40.0 0.2 6.2e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 KH domain Ferric_reduct PF01794.19 KKA01123.1 - 1.4e-16 60.8 16.6 1.4e-16 60.8 16.6 3.2 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKA01123.1 - 8.8e-14 51.5 0.1 2e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KKA01123.1 - 7.4e-12 45.7 0.1 1e-10 41.9 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KKA01123.1 - 0.035 14.8 0.0 0.067 13.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain RNase_PH_C PF03725.15 KKA01124.1 - 0.069 13.2 1.0 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Sld5 PF05916.11 KKA01125.1 - 3.6e-10 40.3 0.0 5.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF1944 PF09175.10 KKA01126.1 - 0.05 13.4 0.2 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1944) DUF3021 PF11457.8 KKA01126.1 - 0.069 13.5 6.0 1.5 9.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF4064 PF13273.6 KKA01126.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Glycophorin_A PF01102.18 KKA01126.1 - 0.14 12.4 2.6 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Glycophorin A Sterol_MT_C PF08498.10 KKA01127.1 - 2.1e-26 92.0 0.2 4.2e-26 91.0 0.1 1.6 2 0 0 2 2 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KKA01127.1 - 1.6e-20 73.5 0.0 4.1e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKA01127.1 - 3.3e-19 69.2 0.0 5.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA01127.1 - 3.9e-18 65.9 0.0 1.1e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KKA01127.1 - 1.7e-13 50.5 0.4 2.5e-13 50.0 0.4 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KKA01127.1 - 5.4e-13 49.1 0.0 9.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA01127.1 - 1.1e-10 42.1 0.8 4.5e-10 40.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKA01127.1 - 1.1e-09 38.0 0.0 1.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KKA01127.1 - 6.5e-05 22.6 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KKA01127.1 - 0.00095 18.6 0.1 0.0078 15.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KKA01127.1 - 0.0017 18.4 1.1 0.0047 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KKA01127.1 - 0.0045 16.3 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltr_RsmB-F PF01189.17 KKA01127.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 KKA01127.1 - 0.074 12.5 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KKA01127.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PX PF00787.24 KKA01128.1 - 5.1e-12 45.8 0.6 5.1e-12 45.8 0.6 2.7 3 0 0 3 3 3 1 PX domain Sugar_tr PF00083.24 KKA01129.1 - 1.3e-18 67.1 28.3 1.6e-11 43.7 11.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKA01129.1 - 2.6e-14 52.9 35.4 2.7e-12 46.3 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily M16C_assoc PF08367.11 KKA01130.1 - 6.9e-53 179.3 3.1 1.3e-52 178.4 3.1 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KKA01130.1 - 9.4e-20 71.4 1.2 2.2e-11 44.1 0.3 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKA01130.1 - 6.8e-09 35.9 0.2 1e-07 32.1 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) MutS_IV PF05190.18 KKA01130.1 - 0.027 14.8 0.4 0.18 12.1 0.4 2.5 1 0 0 1 1 1 0 MutS family domain IV DUF3089 PF11288.8 KKA01130.1 - 0.16 11.5 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Spt5-NGN PF03439.13 KKA01131.1 - 5.4e-20 71.1 0.0 1.4e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KKA01131.1 - 5e-16 59.5 12.4 5e-16 59.5 12.4 3.5 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KKA01131.1 - 3.8e-09 36.2 6.2 0.35 10.9 0.0 5.0 4 0 0 4 4 4 4 KOW motif Sugar_tr PF00083.24 KKA01132.1 - 5.2e-20 71.7 26.5 1.2e-18 67.3 6.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKA01132.1 - 1.1e-14 54.2 41.1 3.5e-13 49.2 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Importin_rep_5 PF18816.1 KKA01134.1 - 0.071 13.4 0.3 0.85 10.0 0.1 2.5 2 0 0 2 2 2 0 Importin repeat Rad51 PF08423.11 KKA01135.1 - 1.5e-09 37.5 0.1 9.5e-08 31.6 0.1 3.2 1 1 1 2 2 2 1 Rad51 AAA_25 PF13481.6 KKA01135.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKA01135.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecG_N PF17190.4 KKA01135.1 - 0.88 10.3 9.4 2.3 9.0 0.5 3.0 3 0 0 3 3 3 0 RecG N-terminal helical domain EABR PF12180.8 KKA01135.1 - 7.5 6.3 6.2 5.2 6.8 0.1 3.5 4 0 0 4 4 4 0 TSG101 and ALIX binding domain of CEP55 Aldedh PF00171.22 KKA01136.1 - 1.7e-131 439.0 0.0 1.9e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2846 PF11008.8 KKA01136.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) RCR PF12273.8 KKA01137.1 - 2.2e-24 86.4 0.1 3.8e-24 85.6 0.1 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4834 PF16118.5 KKA01137.1 - 0.04 14.9 2.7 1.4 9.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2140 PF09911.9 KKA01137.1 - 1.3 8.5 3.3 2.1 7.9 3.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Prenyltransf PF01255.19 KKA01138.1 - 3.8e-61 206.5 0.4 5e-61 206.1 0.4 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_C34 PF05413.11 KKA01138.1 - 0.098 12.9 0.2 0.45 10.8 0.2 2.1 2 1 1 3 3 3 0 Putative closterovirus papain-like endopeptidase polyprenyl_synt PF00348.17 KKA01139.1 - 4e-66 222.7 0.2 9.5e-60 201.8 0.2 2.8 2 1 0 2 2 2 2 Polyprenyl synthetase Mannosyl_trans2 PF04188.13 KKA01140.1 - 2e-31 109.8 44.6 1.3e-28 100.6 44.6 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Ran_BP1 PF00638.18 KKA01141.1 - 1e-44 151.7 0.9 2e-44 150.8 0.9 1.5 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.14 KKA01141.1 - 0.0024 17.6 0.1 0.0035 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.23 KKA01141.1 - 0.0097 15.8 0.1 3.7 7.5 0.1 2.3 2 0 0 2 2 2 2 WH1 domain Trehalase PF01204.18 KKA01142.1 - 1.9e-163 545.0 2.2 2.3e-163 544.7 2.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KKA01142.1 - 4.1e-13 48.8 1.6 7.1e-13 48.0 1.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain LptF_LptG PF03739.14 KKA01142.1 - 0.033 13.0 0.0 0.068 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Histone PF00125.24 KKA01143.1 - 1.4e-16 61.0 1.1 1.9e-16 60.6 1.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKA01143.1 - 1.9e-05 24.9 0.1 3.6e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KKA01143.1 - 0.023 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 KKA01143.1 - 0.029 14.4 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein TFIID_20kDa PF03847.13 KKA01143.1 - 0.04 14.4 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KKA01143.1 - 0.066 13.3 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 KKA01144.1 - 1.4e-19 69.5 0.9 2.8e-19 68.6 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KKA01144.1 - 3.4e-19 69.5 0.0 4.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKA01144.1 - 3.2e-06 27.3 0.0 4.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 KKA01144.1 - 0.063 13.0 0.7 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) DUF155 PF02582.14 KKA01145.1 - 1.9e-53 181.1 1.7 1.9e-53 181.1 1.7 2.1 2 1 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KKA01145.1 - 0.071 13.6 1.4 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Mitovir_RNA_pol PF05919.11 KKA01146.1 - 0.28 10.3 10.1 0.53 9.4 9.8 1.5 1 1 1 2 2 2 0 Mitovirus RNA-dependent RNA polymerase DRIM PF07539.12 KKA01147.1 - 1.6e-136 456.2 12.1 1.6e-136 456.2 12.1 4.1 3 1 1 4 4 4 1 Down-regulated in metastasis HEAT PF02985.22 KKA01147.1 - 0.04 14.2 2.6 2.1e+02 2.6 0.0 6.0 5 0 0 5 5 5 0 HEAT repeat CHASE3 PF05227.13 KKA01147.1 - 0.58 10.1 2.8 0.63 10.0 0.7 2.1 2 0 0 2 2 2 0 CHASE3 domain Tau95_N PF17682.1 KKA01147.1 - 1 9.6 5.7 0.7 10.1 0.1 3.4 3 0 0 3 3 3 0 Tau95 Triple barrel domain SMI1_KNR4 PF09346.10 KKA01148.1 - 1.9e-32 112.4 2.5 2.1e-32 112.3 0.0 2.4 3 1 0 3 3 3 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KKA01148.1 - 0.0011 19.4 4.3 0.0053 17.2 0.0 3.5 3 2 1 4 4 4 1 SMI1-KNR4 cell-wall Pex24p PF06398.11 KKA01150.1 - 4.7e-10 39.0 26.7 2.6e-08 33.2 14.8 2.3 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin Importin_rep_6 PF18829.1 KKA01151.1 - 1.7e-27 95.7 1.8 1.2e-26 92.9 1.8 2.6 1 0 0 1 1 1 1 Importin repeat 6 Importin_rep_4 PF18808.1 KKA01151.1 - 3.3e-18 65.7 1.4 1.5e-17 63.6 0.0 3.0 3 0 0 3 3 3 1 Importin repeat Importin_rep_5 PF18816.1 KKA01151.1 - 4.8e-14 52.4 1.0 1.5e-13 50.8 1.0 2.0 1 0 0 1 1 1 1 Importin repeat HEAT_EZ PF13513.6 KKA01151.1 - 3.3e-05 24.3 0.1 0.0074 16.8 0.0 4.5 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KKA01151.1 - 0.00014 21.8 0.0 0.0035 17.5 0.0 3.6 2 0 0 2 2 2 1 HEAT repeat Cnd3 PF12719.7 KKA01151.1 - 0.00022 20.5 2.6 0.23 10.6 0.4 2.9 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KKA01151.1 - 0.0022 18.4 0.0 0.1 13.0 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KKA01151.1 - 0.0022 18.5 2.2 0.26 11.9 0.0 4.6 3 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 KKA01151.1 - 0.028 14.5 0.6 0.36 11.0 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF1539 PF07560.11 KKA01151.1 - 0.059 13.4 0.9 1.3 9.1 0.0 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) MRP-L47 PF06984.13 KKA01152.1 - 1.8e-13 50.4 2.1 4e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) PIF1 PF05970.14 KKA01153.1 - 1.3e-30 106.8 3.0 1.2e-21 77.3 0.2 2.9 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KKA01153.1 - 4.8e-09 36.2 0.0 1.5e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KKA01153.1 - 0.027 14.8 0.0 0.07 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain SH3_13 PF18335.1 KKA01153.1 - 0.031 14.1 0.1 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 KKA01153.1 - 0.044 13.6 0.2 0.13 12.1 0.2 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KKA01153.1 - 0.4 10.4 2.2 1.5 8.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 KKA01154.1 - 3.9e-45 154.6 3.9 6.4e-44 150.6 3.9 3.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KKA01154.1 - 4.4e-19 69.0 0.0 9.6e-18 64.6 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKA01154.1 - 1.4e-13 51.4 0.0 8.1e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KKA01154.1 - 2.2e-07 30.9 0.6 0.00043 20.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_7 PF12775.7 KKA01154.1 - 5.1e-06 26.1 0.7 1.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KKA01154.1 - 7.3e-06 26.0 0.2 0.029 14.3 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA_22 PF13401.6 KKA01154.1 - 2.1e-05 24.8 0.2 8.6e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KKA01154.1 - 3.8e-05 23.4 1.6 6.5e-05 22.6 1.6 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KKA01154.1 - 4.5e-05 22.7 0.0 8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.14 KKA01154.1 - 5.1e-05 23.3 1.4 0.00015 21.8 0.2 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KKA01154.1 - 0.00011 22.2 0.9 0.00036 20.5 0.9 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KKA01154.1 - 0.00015 22.2 0.0 0.00046 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 KKA01154.1 - 0.00018 20.9 0.1 0.00028 20.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KKA01154.1 - 0.00019 21.5 0.3 0.0016 18.5 0.3 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKA01154.1 - 0.00027 20.7 1.5 0.066 12.9 0.5 4.0 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KKA01154.1 - 0.0004 20.2 0.3 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKA01154.1 - 0.00085 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KKA01154.1 - 0.00099 19.7 0.4 0.0034 17.9 0.1 2.1 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 KKA01154.1 - 0.0022 18.0 2.2 0.0028 17.7 0.5 2.0 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 KKA01154.1 - 0.0033 17.9 0.8 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKA01154.1 - 0.0035 16.6 0.0 0.0075 15.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain SH3_13 PF18335.1 KKA01154.1 - 0.0081 16.0 0.1 0.042 13.7 0.1 2.2 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 KKA01154.1 - 0.023 14.5 0.1 0.053 13.4 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 KKA01154.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KKA01154.1 - 0.034 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KKA01154.1 - 0.041 12.8 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 KKA01154.1 - 0.052 12.9 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KKA01154.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 KKA01154.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KKA01154.1 - 0.16 12.5 0.1 0.16 12.5 0.1 2.7 2 2 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 KKA01154.1 - 0.17 12.3 1.7 0.42 11.0 0.1 2.7 3 1 0 3 3 1 0 RNA helicase 2Fe-2S_thioredx PF01257.19 KKA01155.1 - 0.25 11.2 0.6 0.43 10.4 0.1 1.7 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin Ras PF00071.22 KKA01156.1 - 1.2e-24 86.7 0.2 2.1e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA01156.1 - 1.8e-19 70.1 0.0 3.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA01156.1 - 7.9e-08 31.9 0.1 1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKA01156.1 - 2.3e-05 23.9 0.1 3.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA01156.1 - 0.011 15.8 0.3 0.021 14.9 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DLIC PF05783.11 KKA01156.1 - 0.05 12.4 0.1 0.62 8.8 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) FeoB_N PF02421.18 KKA01156.1 - 0.071 12.6 1.5 0.38 10.3 0.4 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_14 PF13173.6 KKA01156.1 - 0.21 11.6 1.8 0.27 11.3 0.1 2.1 2 1 1 3 3 3 0 AAA domain Mei5_like PF17021.5 KKA01156.1 - 2.3 8.3 7.1 8.1 6.5 4.0 2.5 3 0 0 3 3 3 0 Putative double-strand recombination repair-like AAA PF00004.29 KKA01157.1 - 1.8e-12 47.8 0.0 6.6e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKA01157.1 - 6e-08 33.3 0.1 1.3e-06 28.9 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKA01157.1 - 5e-07 30.1 0.0 1.4e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KKA01157.1 - 0.0013 18.0 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_14 PF13173.6 KKA01157.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 3.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KKA01157.1 - 0.041 14.2 1.0 0.21 11.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KKA01157.1 - 0.047 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_lid_10 PF17872.1 KKA01157.1 - 0.049 13.8 0.6 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA lid domain DUF3983 PF13137.6 KKA01157.1 - 0.49 10.2 2.1 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) ResIII PF04851.15 KKA01157.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.6 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit HTH_DeoR PF08220.12 KKA01158.1 - 0.064 13.0 3.0 0.36 10.6 0.0 3.0 4 0 0 4 4 4 0 DeoR-like helix-turn-helix domain Dak1 PF02733.17 KKA01159.1 - 2.3e-96 322.3 0.1 3.3e-96 321.9 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KKA01159.1 - 1.4e-45 155.3 0.0 2.6e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain POB3_N PF17292.2 KKA01160.1 - 8.8e-29 99.8 0.1 5.5e-23 81.2 0.0 3.0 2 1 1 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KKA01160.1 - 2.3e-27 94.7 1.0 1.1e-26 92.5 0.2 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KKA01160.1 - 4.5e-22 78.3 0.0 5.2e-21 74.9 0.0 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Chromo_2 PF18704.1 KKA01160.1 - 0.054 13.8 0.0 6.5 7.1 0.0 3.1 2 0 0 2 2 2 0 Chromatin organization modifier domain 2 VirC2 PF07181.11 KKA01160.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 VirC2 protein DegV PF02645.16 KKA01160.1 - 0.097 12.0 0.0 0.32 10.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 vATP-synt_AC39 PF01992.16 KKA01162.1 - 1.4e-79 268.1 7.1 1.5e-79 267.9 7.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Alliinase_C PF04864.13 KKA01162.1 - 0.023 13.6 0.3 0.037 12.9 0.3 1.3 1 0 0 1 1 1 0 Allinase NiFeSe_Hases PF00374.19 KKA01162.1 - 0.081 11.8 2.8 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Nickel-dependent hydrogenase Gliadin PF13016.6 KKA01162.1 - 0.16 12.4 1.2 0.65 10.4 0.4 2.3 3 0 0 3 3 3 0 Cys-rich Gliadin N-terminal C2 PF00168.30 KKA01163.1 - 1.5e-41 140.8 4.1 1.4e-19 70.3 0.2 4.8 5 0 0 5 5 5 3 C2 domain SMP_LBD PF17047.5 KKA01163.1 - 0.0091 15.5 0.1 0.024 14.1 0.1 1.7 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain adh_short PF00106.25 KKA01163.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NOA36 PF06524.12 KKA01163.1 - 0.84 8.9 4.0 1.7 7.9 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein PA28_alpha PF02251.18 KKA01164.1 - 0.81 9.8 5.4 1.1 9.4 0.1 3.4 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit GerD PF17898.1 KKA01164.1 - 1.2 9.1 6.7 0.92 9.5 2.7 2.5 2 0 0 2 2 2 0 Spore germination GerD central core domain FKBP_C PF00254.28 KKA01165.1 - 7.5e-27 93.5 0.1 2e-26 92.2 0.1 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KKA01165.1 - 1.6e-19 70.4 0.1 1.6e-19 70.4 0.1 2.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain DUF3349 PF11829.8 KKA01165.1 - 1.9 9.3 5.3 0.45 11.3 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) RNA_pol_L_2 PF13656.6 KKA01166.1 - 3.1e-30 103.8 0.1 5.1e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKA01166.1 - 3.1e-07 29.7 0.0 6.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1178 PF06676.11 KKA01166.1 - 0.047 14.1 0.0 0.064 13.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Cyt-b5 PF00173.28 KKA01167.1 - 1.6e-17 63.4 0.1 2.1e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.26 KKA01168.1 - 1e-13 51.4 0.0 2.6e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KKA01168.1 - 2.4e-11 43.2 6.0 5.1e-11 42.1 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KKA01168.1 - 4.9e-07 30.0 10.1 4.9e-07 30.0 10.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KKA01168.1 - 0.00027 20.8 7.5 0.0005 20.0 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 KKA01168.1 - 0.00076 19.8 0.0 0.0029 17.9 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KKA01168.1 - 0.0014 18.4 9.7 0.0035 17.2 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KKA01168.1 - 0.0041 17.1 2.2 0.0041 17.1 2.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KKA01168.1 - 0.02 15.2 6.4 0.02 15.2 6.4 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KKA01168.1 - 0.026 14.4 9.8 0.055 13.3 9.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.14 KKA01168.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-RING_UBOX PF13445.6 KKA01168.1 - 0.17 11.9 9.0 0.45 10.6 9.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKA01168.1 - 0.47 10.1 8.3 0.34 10.6 5.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Malate_synthase PF01274.22 KKA01169.1 - 1.8e-165 551.2 0.0 2.3e-165 550.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KKA01169.1 - 0.015 14.4 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family NUDIX PF00293.28 KKA01170.1 - 6.9e-14 52.0 0.0 1.4e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 KKA01170.1 - 2.7e-10 40.4 1.6 1.9e-09 37.7 0.5 2.6 2 1 0 2 2 2 1 Dcp2, box A domain DBC1 PF14443.6 KKA01170.1 - 0.049 13.6 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 DBC1 CTU2 PF10288.9 KKA01172.1 - 5.4e-19 68.5 0.8 1.2e-18 67.4 0.8 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Herpes_UL92 PF03048.14 KKA01172.1 - 0.97 9.2 10.8 0.28 11.0 2.4 2.6 2 1 0 2 2 2 0 UL92 family FERM_N_2 PF18038.1 KKA01172.1 - 4.5 8.2 9.3 18 6.3 0.1 4.1 3 1 1 4 4 4 0 FERM N-terminal domain Pet191_N PF10203.9 KKA01173.1 - 0.0029 17.9 2.7 0.0053 17.0 2.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KKA01173.1 - 0.0059 16.7 5.2 0.013 15.7 5.2 1.5 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KKA01173.1 - 0.022 15.0 1.2 0.038 14.2 1.2 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type MFA1_2 PF17317.2 KKA01173.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.5 2 1 0 2 2 2 0 Mating hormone A-factor 1&2 TPR_1 PF00515.28 KKA01174.1 - 5.8e-14 51.2 7.2 0.0024 17.6 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKA01174.1 - 2.9e-11 42.6 7.9 0.0041 17.1 0.0 6.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKA01174.1 - 3.2e-07 30.3 2.3 2.8 8.5 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKA01174.1 - 6.7e-07 29.8 0.1 0.37 11.5 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKA01174.1 - 2.1e-06 28.1 0.0 9.1 7.4 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKA01174.1 - 5.1e-06 26.9 9.0 0.013 15.9 0.1 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKA01174.1 - 1.7e-05 24.7 2.3 2 8.9 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKA01174.1 - 4.7e-05 23.1 1.0 0.74 10.0 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKA01174.1 - 0.0002 21.8 3.4 4.8 8.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKA01174.1 - 0.003 17.8 2.5 2.5 8.4 0.1 5.5 7 1 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA01174.1 - 0.0045 17.2 11.9 0.038 14.2 3.3 4.7 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKA01174.1 - 0.019 14.7 9.6 17 5.2 0.3 5.6 5 1 1 6 6 6 0 TPR repeat TPR_21 PF09976.9 KKA01174.1 - 0.042 13.5 5.1 8.9 6.0 0.1 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KKA01174.1 - 0.085 13.0 0.0 0.75 10.0 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat RasGEF_N_2 PF14663.6 KKA01174.1 - 0.35 11.3 3.0 2.1 8.8 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SET PF00856.28 KKA01176.1 - 4.6e-19 69.4 0.1 4.6e-19 69.4 0.1 3.7 2 1 0 2 2 2 1 SET domain N-SET PF11764.8 KKA01176.1 - 3.6e-08 33.7 0.1 3.6e-08 33.7 0.1 3.0 2 1 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N Gar1 PF04410.14 KKA01177.1 - 1.1e-23 83.7 5.7 1.1e-23 83.7 5.7 2.8 4 0 0 4 4 4 1 Gar1/Naf1 RNA binding region PAT1 PF09770.9 KKA01177.1 - 0.31 9.3 36.2 0.47 8.7 36.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_S18 PF01084.20 KKA01178.1 - 2.4e-06 27.6 0.3 5.1e-06 26.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S18 N1221 PF07923.13 KKA01179.1 - 2.2e-21 76.3 8.9 2.2e-21 76.3 8.9 2.0 2 0 0 2 2 2 1 N1221-like protein DUF3402 PF11882.8 KKA01179.1 - 2.6e-18 66.4 11.8 5.7e-15 55.4 0.2 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF3402) KaiA PF07688.12 KKA01179.1 - 0.17 12.0 5.1 0.059 13.5 0.5 2.7 2 1 0 2 2 2 0 KaiA C-terminal domain DSPc PF00782.20 KKA01180.1 - 1.3e-12 47.7 0.1 4.3e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKA01180.1 - 8.7e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKA01180.1 - 0.024 14.8 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate FeS_assembly_P PF01883.19 KKA01181.1 - 3.5e-05 23.9 0.0 7.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Svf1 PF08622.10 KKA01181.1 - 0.025 14.6 0.7 0.05 13.7 0.4 1.8 2 1 0 2 2 2 0 Svf1-like N-terminal lipocalin domain DUF3839 PF12943.7 KKA01181.1 - 0.22 11.0 4.9 0.32 10.4 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) Tom22 PF04281.13 KKA01182.1 - 1.8e-34 118.5 4.0 2.3e-34 118.2 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 SID-1_RNA_chan PF13965.6 KKA01182.1 - 0.019 13.4 0.4 0.022 13.2 0.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Importin_rep_6 PF18829.1 KKA01182.1 - 0.11 12.6 5.2 0.21 11.8 5.2 1.6 1 1 0 1 1 1 0 Importin repeat 6 CorA PF01544.18 KKA01182.1 - 3 7.1 7.1 2.9 7.1 4.1 2.0 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein GNAT_acetyltr_2 PF13718.6 KKA01183.1 - 6.1e-100 333.3 0.0 1.7e-99 331.9 0.0 1.8 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KKA01183.1 - 2.5e-90 302.3 6.4 4.4e-90 301.5 6.4 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KKA01183.1 - 1.4e-65 220.5 0.0 6.5e-65 218.3 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KKA01183.1 - 4e-33 113.2 0.0 1.3e-32 111.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 KKA01183.1 - 0.0079 16.5 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain YARHG PF13308.6 KKA01183.1 - 0.012 15.4 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 0 YARHG domain DEAD PF00270.29 KKA01183.1 - 0.026 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma70_r4_2 PF08281.12 KKA01183.1 - 0.032 13.9 0.1 2.2 8.0 0.0 3.0 2 0 0 2 2 2 0 Sigma-70, region 4 NDT80_PhoG PF05224.12 KKA01184.1 - 3.6e-47 161.0 0.2 8.8e-47 159.7 0.2 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PIR PF00399.19 KKA01185.1 - 2e-43 145.1 94.2 2.3e-08 33.4 6.2 6.7 7 0 0 7 7 7 6 Yeast PIR protein repeat DUF421 PF04239.12 KKA01185.1 - 0.031 14.0 1.5 1.9 8.3 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF421) Ret2_MD PF18528.1 KKA01185.1 - 0.036 14.4 2.2 12 6.3 0.1 3.7 1 1 4 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain p25-alpha PF05517.12 KKA01185.1 - 1.7 8.8 10.2 6.9 6.8 3.0 2.3 1 1 2 3 3 3 0 p25-alpha Plug PF07715.15 KKA01185.1 - 6.9 7.3 27.2 1.3 9.6 2.5 3.9 1 1 2 4 4 4 0 TonB-dependent Receptor Plug Domain Rep_fac-A_C PF08646.10 KKA01186.1 - 1.8e-37 128.3 4.2 4.7e-35 120.5 1.2 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KKA01186.1 - 2.7e-24 84.9 0.3 3.1e-23 81.5 0.0 2.7 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KKA01186.1 - 2.3e-17 62.7 1.4 1.2e-08 34.8 0.0 4.4 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KKA01186.1 - 3.9e-05 23.5 1.2 0.0068 16.1 0.3 3.4 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 KKA01186.1 - 0.0015 18.5 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) Rep-A_N PF04057.12 KKA01186.1 - 0.033 14.2 0.1 0.084 12.9 0.1 1.6 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.14 KKA01186.1 - 0.062 13.6 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF223 TPP1 PF10341.9 KKA01186.1 - 0.098 12.6 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD BRCA-2_OB1 PF09103.10 KKA01186.1 - 0.099 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Rad33 PF08730.10 KKA01187.1 - 2.2e-05 24.5 10.0 0.0023 18.0 7.7 3.1 1 1 1 2 2 2 1 Rad33 CSN7a_helixI PF18392.1 KKA01187.1 - 3.8 7.5 6.6 10 6.1 0.4 2.8 3 0 0 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain EMP24_GP25L PF01105.24 KKA01188.1 - 1.5e-37 129.3 0.0 1.7e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD eIF3g PF12353.8 KKA01189.1 - 1.3e-15 57.9 3.9 1.3e-15 57.9 3.9 2.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KKA01189.1 - 1.5e-11 43.9 0.3 5.7e-11 42.1 0.3 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKA01189.1 - 0.086 12.7 0.2 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif PCI PF01399.27 KKA01190.1 - 1.1e-06 29.0 2.0 1.1e-06 29.0 2.0 3.0 3 1 0 3 3 3 1 PCI domain Dimerisation2 PF16864.5 KKA01190.1 - 0.049 13.6 0.0 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Dimerisation domain BRE1 PF08647.11 KKA01190.1 - 0.063 13.4 6.3 0.066 13.3 2.3 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase 3Beta_HSD PF01073.19 KKA01191.1 - 3.9e-89 298.4 0.0 4.8e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKA01191.1 - 5.7e-31 107.8 0.0 6.9e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKA01191.1 - 6.9e-20 71.7 0.0 1.3e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KKA01191.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KKA01191.1 - 1.6e-12 47.1 0.0 2.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKA01191.1 - 2.1e-12 46.8 0.0 5.2e-11 42.2 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKA01191.1 - 6.1e-09 35.4 0.0 1.5e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KKA01191.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KKA01191.1 - 0.00031 20.7 0.0 0.0036 17.2 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KKA01191.1 - 0.045 13.2 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Vps8 PF12816.7 KKA01192.1 - 1.1e-19 70.8 3.6 2e-19 69.9 0.6 2.4 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Phage_GP20 PF06810.11 KKA01192.1 - 3.8 7.3 8.3 3.6 7.4 0.0 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 WD40 PF00400.32 KKA01193.1 - 2.8e-13 50.1 2.1 0.00011 22.9 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA01193.1 - 1.1e-10 41.6 0.9 0.00094 19.4 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EMP24_GP25L PF01105.24 KKA01194.1 - 2.2e-45 154.8 2.2 3.1e-45 154.4 2.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PA-IIL PF07472.11 KKA01194.1 - 0.093 13.0 0.0 0.23 11.8 0.0 1.8 1 1 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) WD40 PF00400.32 KKA01195.1 - 1.5e-19 70.0 6.2 7.7e-05 23.4 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA01195.1 - 5.3e-13 49.1 5.4 0.00011 22.4 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKA01195.1 - 1.5e-07 31.5 0.8 8.2e-05 22.6 0.4 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKA01195.1 - 0.032 13.2 0.0 0.071 12.1 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Trp_syntA PF00290.20 KKA01196.1 - 8.9e-93 309.9 0.0 1.4e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KKA01196.1 - 8.3e-47 160.0 0.4 1.3e-46 159.4 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rsm22 PF09243.10 KKA01198.1 - 9.7e-16 57.8 1.3 4.6e-10 39.2 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Cgr1 PF03879.14 KKA01200.1 - 1.1e-19 70.8 31.6 1.2e-19 70.6 31.6 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 KKA01200.1 - 0.11 11.6 3.7 0.13 11.4 3.7 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 SLATT_5 PF18160.1 KKA01200.1 - 0.38 10.1 7.5 0.46 9.8 7.5 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Vfa1 PF08432.10 KKA01200.1 - 7.6 6.8 22.0 8.8 6.6 22.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DOR PF14839.6 KKA01200.1 - 10 6.0 13.2 11 5.9 13.2 1.0 1 0 0 1 1 1 0 DOR family DUF1279 PF06916.13 KKA01201.1 - 3e-19 69.4 0.2 7.1e-19 68.1 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Uricase PF01014.18 KKA01202.1 - 1.1e-58 197.1 4.4 2.4e-31 108.7 2.6 2.0 2 0 0 2 2 2 2 Uricase NUC153 PF08159.12 KKA01204.1 - 6.8e-10 38.6 2.4 6.8e-10 38.6 2.4 2.2 3 0 0 3 3 3 1 NUC153 domain WD40 PF00400.32 KKA01204.1 - 0.13 13.2 0.0 28 5.8 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Ras PF00071.22 KKA01206.1 - 2.6e-49 167.0 0.1 4.2e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA01206.1 - 1.5e-18 67.2 0.0 3.7e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA01206.1 - 8.5e-09 35.1 0.1 1.3e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKA01206.1 - 0.015 14.8 0.1 0.034 13.7 0.1 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain YqzE PF14038.6 KKA01206.1 - 0.04 13.9 1.5 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 YqzE-like protein Gly_transf_sug PF04488.15 KKA01207.1 - 5.4e-12 46.2 0.5 1.3e-11 45.0 0.5 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif EptA_B_N PF08019.12 KKA01207.1 - 0.05 13.5 0.2 0.096 12.6 0.2 1.4 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Isochorismatase PF00857.20 KKA01208.1 - 2.7e-23 83.0 0.1 6.4e-23 81.8 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family Glyco_transf_5 PF08323.11 KKA01209.1 - 0.00016 21.5 0.4 0.00026 20.8 0.4 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain FCH PF00611.23 KKA01209.1 - 0.18 12.1 1.5 1.6 9.1 0.1 2.7 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Ribosomal_L24e PF01246.20 KKA01210.1 - 1.8e-29 101.7 0.2 1.8e-29 101.7 0.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e RRM_1 PF00076.22 KKA01211.1 - 3.7e-37 126.0 0.0 5.9e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKA01211.1 - 9.5e-05 22.5 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKA01211.1 - 0.0009 19.2 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KKA01211.1 - 0.028 14.4 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_occluded PF16842.5 KKA01211.1 - 0.12 12.2 0.0 1.8 8.5 0.0 2.3 2 1 0 2 2 2 0 Occluded RNA-recognition motif EF1G PF00647.19 KKA01212.1 - 2.1e-44 149.9 0.2 9.2e-44 147.9 0.1 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKA01212.1 - 1.3e-08 34.9 0.1 1.3e-08 34.9 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKA01212.1 - 0.00025 21.0 0.4 0.00069 19.6 0.4 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKA01212.1 - 0.0025 18.0 0.1 0.0075 16.4 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKA01212.1 - 0.071 13.5 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SURF6 PF04935.12 KKA01213.1 - 6.6e-26 91.4 34.4 6.6e-26 91.4 34.4 3.1 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KKA01213.1 - 4.4e-08 33.6 8.9 4.4e-08 33.6 8.9 7.2 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 CT_C_D PF02682.16 KKA01213.1 - 4.2 7.1 4.6 1.2 8.8 0.7 2.1 2 1 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D UBX PF00789.20 KKA01214.1 - 1.6e-12 47.4 1.4 4.2e-12 46.1 0.2 2.2 2 0 0 2 2 2 1 UBX domain GST_C_5 PF16865.5 KKA01214.1 - 0.091 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 KKA01215.1 - 1.6e-23 83.6 0.0 2.5e-22 79.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKA01215.1 - 8.9e-13 49.3 0.0 2.3e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKA01215.1 - 1.6e-11 43.9 0.0 2.5e-06 26.9 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KKA01215.1 - 0.00012 21.7 0.0 0.00031 20.4 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 KKA01215.1 - 0.00022 20.1 0.0 0.0018 17.0 0.0 2.4 3 0 0 3 3 3 1 Ndr family Esterase PF00756.20 KKA01215.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KKA01215.1 - 0.0022 17.4 0.1 0.0022 17.4 0.1 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KKA01215.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3641 PF12345.8 KKA01215.1 - 0.0064 16.5 0.2 0.042 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) Lipase_3 PF01764.25 KKA01215.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 KKA01215.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 KKA01215.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 KKA01215.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KKA01215.1 - 0.039 13.9 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KKA01215.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KKA01215.1 - 0.071 12.9 0.0 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 KKA01215.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ank_2 PF12796.7 KKA01216.1 - 1.2e-25 89.9 19.1 6.4e-12 45.9 2.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKA01216.1 - 7.5e-17 61.5 5.2 3.6e-08 33.8 0.2 3.5 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA01216.1 - 1.2e-15 56.0 10.1 0.00017 21.7 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KKA01216.1 - 4.8e-14 52.1 10.6 4.3e-05 23.8 0.5 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KKA01216.1 - 1.7e-13 50.5 5.2 2e-05 24.7 0.3 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) zf-CHY PF05495.12 KKA01217.1 - 8.3e-08 32.6 19.5 2.3e-07 31.2 19.5 1.8 1 1 0 1 1 1 1 CHY zinc finger zf-Sec23_Sec24 PF04810.15 KKA01217.1 - 0.0022 18.0 7.3 0.21 11.7 0.5 2.6 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Zn_ribbon_recom PF13408.6 KKA01217.1 - 0.0091 16.5 2.8 0.0091 16.5 2.8 2.2 2 1 0 2 2 2 1 Recombinase zinc beta ribbon domain PSCyt3 PF07627.11 KKA01217.1 - 0.038 14.2 5.2 0.11 12.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) zf-RING_4 PF14570.6 KKA01217.1 - 0.071 12.9 0.6 0.071 12.9 0.6 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF1815 PF08844.10 KKA01217.1 - 0.21 11.6 2.2 0.39 10.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1815) zinc-ribbons_6 PF07191.12 KKA01217.1 - 0.63 10.1 11.7 0.8 9.7 1.5 2.4 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.19 KKA01217.1 - 1.7 8.7 7.4 6.1 6.9 7.4 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ParBc PF02195.18 KKA01218.1 - 0.0012 19.1 0.0 0.0042 17.3 0.0 1.8 1 1 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.18 KKA01219.1 - 6.4e-50 169.4 0.0 3.6e-49 166.9 0.1 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KKA01219.1 - 1.8e-44 151.2 0.1 2.6e-44 150.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKA01219.1 - 8.4e-05 21.7 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KKA01219.1 - 0.028 14.0 0.4 1.3 8.6 0.4 2.5 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase G-alpha PF00503.20 KKA01220.1 - 1.3e-107 360.1 11.0 1.6e-107 359.7 11.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKA01220.1 - 1.4e-15 57.2 0.4 1.6e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKA01220.1 - 0.0073 15.7 1.4 0.53 9.6 0.3 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 KKA01220.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KKA01220.1 - 0.015 15.4 0.0 0.79 9.8 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase Roc PF08477.13 KKA01220.1 - 0.016 15.4 0.6 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KKA01220.1 - 0.15 11.8 0.2 0.44 10.3 0.2 1.8 1 1 0 1 1 1 0 P-loop containing region of AAA domain Cyto_heme_lyase PF01265.17 KKA01221.1 - 1.8e-44 152.5 7.4 8e-43 147.1 7.4 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Flavoprotein PF02441.19 KKA01222.1 - 3.8e-46 156.7 0.0 6.3e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein RRN3 PF05327.11 KKA01222.1 - 0.38 9.2 6.3 0.65 8.5 6.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CM2 PF03021.14 KKA01222.1 - 2.6 7.9 4.5 1.4 8.8 1.2 2.1 2 0 0 2 2 2 0 Influenza C virus M2 protein CDC45 PF02724.14 KKA01222.1 - 3.3 5.9 8.0 6.8 4.8 8.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S24 PF00717.23 KKA01223.1 - 1.4e-07 31.4 0.1 2.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like ARPC4 PF05856.12 KKA01224.1 - 1.1e-66 223.6 8.5 1.2e-66 223.5 8.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) AGS_C PF18134.1 KKA01224.1 - 0.024 14.6 0.4 0.035 14.1 0.4 1.4 1 1 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain Fungal_trans PF04082.18 KKA01225.1 - 1.3e-20 73.6 0.9 1.3e-20 73.6 0.9 3.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA01225.1 - 0.00057 20.0 9.5 0.0012 18.9 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEGA PF08308.11 KKA01225.1 - 0.54 10.2 3.2 0.45 10.4 0.2 2.3 2 0 0 2 2 2 0 PEGA domain DUF3826 PF12875.7 KKA01226.1 - 0.0055 16.9 8.0 0.0095 16.1 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) MAS20 PF02064.15 KKA01226.1 - 0.96 9.5 9.5 1.9 8.6 9.5 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Npa1 PF11707.8 KKA01227.1 - 1.4e-67 228.5 10.4 1.4e-67 228.5 10.4 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KKA01227.1 - 3.2e-31 108.5 3.5 1.2e-30 106.7 0.3 3.4 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Fungal_trans PF04082.18 KKA01228.1 - 1.8e-15 56.7 0.7 4.7e-15 55.3 0.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA01228.1 - 0.00012 22.1 8.0 0.00035 20.6 8.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pet127 PF08634.10 KKA01228.1 - 0.016 14.7 0.3 0.045 13.2 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Mt_ATP-synt_D PF05873.12 KKA01229.1 - 2.8e-08 33.8 2.9 3.7e-08 33.4 2.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LepB_N PF18640.1 KKA01229.1 - 0.021 14.5 0.7 0.03 13.9 0.7 1.2 1 0 0 1 1 1 0 LepB N-terminal domain p25-alpha PF05517.12 KKA01229.1 - 0.085 13.0 1.0 0.14 12.3 1.0 1.5 1 1 0 1 1 1 0 p25-alpha AAA_12 PF13087.6 KKA01230.1 - 4.8e-57 192.8 0.4 4.8e-57 192.8 0.4 2.8 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KKA01230.1 - 4.8e-49 167.5 1.6 8.3e-49 166.7 1.6 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKA01230.1 - 1.7e-08 34.9 0.0 6.9e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKA01230.1 - 4.5e-07 29.9 0.7 0.026 14.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KKA01230.1 - 8e-06 25.7 0.0 0.096 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KKA01230.1 - 0.0026 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KKA01230.1 - 0.038 14.3 0.4 1.4 9.2 0.5 2.9 2 1 0 2 2 2 0 AAA domain DUF1283 PF06932.11 KKA01230.1 - 0.25 11.6 1.7 0.82 9.9 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) DUF1759 PF03564.15 KKA01230.1 - 0.34 10.8 4.7 0.42 10.5 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) AAA_14 PF13173.6 KKA01230.1 - 0.65 10.0 5.0 16 5.6 0.1 3.3 3 0 0 3 3 3 0 AAA domain Chordopox_L2 PF05803.12 KKA01230.1 - 1.2 9.0 3.2 5.8 6.8 0.4 2.8 2 0 0 2 2 2 0 Chordopoxvirus L2 protein WD40 PF00400.32 KKA01231.1 - 4e-14 52.8 1.9 0.0012 19.6 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA01231.1 - 4.9e-05 23.6 0.0 0.023 15.0 0.0 3.5 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Apc15p PF05841.11 KKA01232.1 - 4.6e-08 33.9 0.4 4.6e-08 33.9 0.4 1.9 2 1 0 2 2 2 1 Apc15p protein SPACA7 PF15307.6 KKA01232.1 - 0.067 13.5 3.6 0.89 9.9 1.0 2.4 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 TMEM51 PF15345.6 KKA01232.1 - 0.25 11.2 2.7 0.66 9.8 0.3 2.1 1 1 1 2 2 2 0 Transmembrane protein 51 DSPc PF00782.20 KKA01233.1 - 9.6e-08 31.9 7.2 1.9e-07 30.9 3.8 2.6 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.14 KKA01233.1 - 0.0051 17.0 0.2 0.015 15.5 0.2 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Trm112p PF03966.16 KKA01233.1 - 0.054 14.1 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Trm112p-like protein YjeF_N PF03853.15 KKA01233.1 - 0.14 12.1 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus PPTA PF01239.22 KKA01234.1 - 4.9e-23 80.1 16.6 0.00013 21.5 0.9 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Ank_4 PF13637.6 KKA01235.1 - 1.5e-13 50.9 2.6 6.3e-10 39.4 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA01235.1 - 3.2e-11 42.4 0.7 0.00043 20.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KKA01235.1 - 6e-11 42.4 1.3 3.8e-06 27.1 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKA01235.1 - 1.8e-10 41.2 0.3 6.9e-10 39.4 0.3 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 KKA01235.1 - 6e-09 35.9 0.7 3.5e-08 33.4 0.7 2.4 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 KKA01235.1 - 2.3e-08 34.1 0.3 0.018 15.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat WD40 PF00400.32 KKA01236.1 - 6e-22 77.5 7.6 1.9e-05 25.3 0.4 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA01236.1 - 1.6e-06 28.3 0.5 0.035 14.4 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKA01236.1 - 1.9e-05 23.6 4.9 0.42 9.3 0.0 4.7 1 1 2 4 4 4 3 Nup133 N terminal like WD40_like PF17005.5 KKA01236.1 - 0.34 10.2 8.3 3.6 6.8 0.1 3.8 1 1 1 3 3 3 0 WD40-like domain Med19 PF10278.9 KKA01236.1 - 1.3 9.0 9.6 3 7.7 9.6 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AlaDh_PNT_N PF05222.15 KKA01237.1 - 2.9e-28 98.9 0.0 4.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KKA01237.1 - 0.016 14.5 0.0 0.049 12.9 0.0 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADK PF00406.22 KKA01239.1 - 3.3e-44 150.6 0.1 4.1e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKA01239.1 - 5.2e-35 120.8 0.1 7.3e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKA01239.1 - 6.1e-09 36.5 0.0 9.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KKA01239.1 - 6.3e-06 26.0 1.8 0.0034 17.1 0.7 2.1 1 1 1 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 KKA01239.1 - 0.0028 17.8 0.0 0.0077 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKA01239.1 - 0.022 15.2 0.2 0.045 14.2 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KKA01239.1 - 0.066 12.8 0.1 0.07 12.7 0.1 1.3 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Pan3_PK PF18101.1 KKA01240.1 - 1.8e-21 76.6 3.5 3.4e-21 75.7 0.5 2.7 3 0 0 3 3 3 1 Pan3 Pseudokinase domain Sec34 PF04136.15 KKA01240.1 - 1.6 8.6 9.3 1.5 8.7 0.1 3.5 4 0 0 4 4 4 0 Sec34-like family BPL_N PF09825.9 KKA01243.1 - 1e-76 258.5 0.0 1.3e-76 258.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KKA01243.1 - 2.7e-08 33.8 0.0 6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 KKA01243.1 - 8.7e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CDP-OH_P_transf PF01066.21 KKA01244.1 - 1.8e-15 57.5 0.6 1.8e-15 57.5 0.6 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UNC45-central PF11701.8 KKA01244.1 - 0.039 13.9 0.3 0.074 13.0 0.3 1.7 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Cpn60_TCP1 PF00118.24 KKA01245.1 - 3.8e-134 448.0 17.6 2.5e-133 445.3 17.6 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Asp PF00026.23 KKA01246.1 - 1.8e-45 155.7 18.0 4.4e-45 154.4 18.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKA01246.1 - 1.6e-08 35.0 4.8 2.8e-07 31.0 0.8 3.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKA01246.1 - 0.0041 17.7 0.1 4.1 8.1 0.0 3.8 4 1 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 KKA01246.1 - 0.0046 17.5 0.5 0.63 10.6 0.0 3.6 3 2 1 4 4 4 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKA01246.1 - 0.033 14.0 0.7 0.76 9.5 0.2 2.7 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Asp PF00026.23 KKA01247.1 - 1.2e-20 74.1 0.1 1.2e-20 74.1 0.1 2.2 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KKA01247.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 KKA01248.1 - 5.6e-65 219.8 9.8 1.2e-64 218.7 9.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKA01248.1 - 8.6e-10 39.1 0.6 8.6e-10 39.1 0.6 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKA01248.1 - 2.8e-05 24.7 0.3 0.18 12.5 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KKA01248.1 - 0.00039 20.9 0.0 0.43 11.2 0.0 3.7 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KKA01248.1 - 0.087 13.1 0.0 10 6.5 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease Peptidase_U4 PF03419.13 KKA01248.1 - 0.089 12.1 0.2 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA D123 PF07065.14 KKA01249.1 - 1.6e-76 257.4 9.6 2e-76 257.1 9.6 1.1 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 KKA01249.1 - 0.089 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 KKA01249.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 ApbA_C PF08546.11 KKA01250.1 - 3.1e-27 95.2 0.0 5.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKA01250.1 - 5.7e-19 68.3 0.0 8.5e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Cry1Ac_D5 PF17997.1 KKA01250.1 - 0.11 12.4 0.3 0.36 10.7 0.1 1.8 1 1 1 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 Glyco_hydro_16 PF00722.21 KKA01251.1 - 2.4e-44 150.9 1.6 6.7e-44 149.5 1.6 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CdiI_2 PF18593.1 KKA01251.1 - 0.039 14.6 1.1 0.3 11.7 0.1 2.6 1 1 1 2 2 2 0 CdiI immunity protein Chitin_bind_1 PF00187.19 KKA01251.1 - 8.1 7.0 11.9 14 6.2 11.9 1.4 1 0 0 1 1 1 0 Chitin recognition protein Coatomer_WDAD PF04053.14 KKA01252.1 - 1.1e-120 403.7 9.8 1.7e-120 403.1 9.8 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KKA01252.1 - 3.2e-76 256.7 0.1 4.7e-76 256.1 0.1 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KKA01252.1 - 1.1e-36 124.2 13.6 4e-08 33.8 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA01252.1 - 7.6e-10 39.0 0.1 4.9e-05 23.6 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKA01252.1 - 0.00078 18.2 4.7 2 7.0 0.1 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 TPR_2 PF07719.17 KKA01252.1 - 0.0073 16.3 0.0 8.7 6.7 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKA01252.1 - 0.023 14.5 0.1 4.4 7.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat LisH PF08513.11 KKA01252.1 - 0.065 13.2 0.0 0.74 9.9 0.0 2.5 2 0 0 2 2 2 0 LisH Tubulin PF00091.25 KKA01253.1 - 2.3e-15 57.3 0.8 2.3e-15 57.3 0.8 2.5 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain Skp1_POZ PF03931.15 KKA01254.1 - 0.069 13.3 7.7 0.22 11.7 0.0 3.8 4 0 0 4 4 4 0 Skp1 family, tetramerisation domain PCI PF01399.27 KKA01255.1 - 6.3e-15 55.6 2.6 6.3e-15 55.6 2.6 2.9 3 2 0 3 3 3 1 PCI domain RPN5_C PF18098.1 KKA01255.1 - 0.00012 22.0 2.8 0.0007 19.7 2.8 2.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Nop14 PF04147.12 KKA01256.1 - 9.7e-117 391.4 82.4 8.6e-70 236.0 19.9 3.5 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.16 KKA01257.1 - 4.9e-119 398.5 38.9 4.9e-119 398.5 38.9 1.7 2 0 0 2 2 2 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.14 KKA01258.1 - 6.4e-13 49.4 0.5 6.4e-13 49.4 0.5 4.3 3 1 1 4 4 4 2 RNA polymerase III RPC4 DUF2505 PF10698.9 KKA01258.1 - 0.024 14.7 0.2 0.061 13.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) F-protein PF00469.20 KKA01258.1 - 1.6 8.3 14.4 0.76 9.3 0.7 3.2 3 0 0 3 3 3 0 Negative factor, (F-Protein) or Nef Sas10 PF09368.10 KKA01259.1 - 4.9e-29 100.6 12.3 4.9e-29 100.6 12.3 2.7 2 0 0 2 2 2 1 Sas10 C-terminal domain Cyclin_N PF00134.23 KKA01260.1 - 1.5e-31 108.8 1.6 5.4e-31 107.0 0.9 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKA01260.1 - 1e-19 70.8 0.0 4.4e-19 68.7 0.0 2.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain Fungal_trans_2 PF11951.8 KKA01261.1 - 1.6e-08 33.8 0.1 3.1e-08 32.8 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA01261.1 - 0.025 14.7 6.3 0.048 13.8 6.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SWI-SNF_Ssr4 PF08549.10 KKA01261.1 - 0.077 11.6 5.9 0.12 11.0 5.9 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Trm56 PF01994.16 KKA01261.1 - 0.078 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Y_phosphatase PF00102.27 KKA01262.1 - 1e-42 146.3 9.0 1e-42 146.3 9.0 2.7 2 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 KKA01262.1 - 0.0013 18.5 1.8 0.0013 18.5 1.8 3.9 4 2 1 5 5 5 1 Dual specificity phosphatase, catalytic domain Peptidase_M24 PF00557.24 KKA01263.1 - 8.3e-46 156.3 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKA01263.1 - 3e-35 120.6 0.1 7e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain LepB_N PF18640.1 KKA01263.1 - 0.076 12.6 0.7 0.16 11.6 0.7 1.5 1 0 0 1 1 1 0 LepB N-terminal domain AAA_23 PF13476.6 KKA01263.1 - 0.086 13.3 1.7 0.16 12.4 1.7 1.4 1 0 0 1 1 1 0 AAA domain RuBisCO_large PF00016.20 KKA01263.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DUF5327 PF17261.2 KKA01264.1 - 0.0057 17.4 0.2 0.021 15.6 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5327) Transp_cyt_pur PF02133.15 KKA01265.1 - 1.6e-59 201.8 39.8 2e-59 201.5 39.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SUN PF03856.13 KKA01266.1 - 3.8e-96 321.3 14.1 3.8e-96 321.3 14.1 2.0 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) PET10 PF17316.2 KKA01266.1 - 0.85 9.1 4.8 4.2 6.8 0.6 2.2 1 1 1 2 2 2 0 Petite colonies protein 10 DnaJ_C PF01556.18 KKA01268.1 - 1.5e-39 135.4 1.9 2e-39 135.1 1.9 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKA01268.1 - 4.9e-26 90.6 0.7 7.9e-26 90.0 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKA01268.1 - 1.4e-13 51.0 16.7 2.5e-13 50.2 16.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Helicase_Sgs1 PF11408.8 KKA01268.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase HypA PF01155.19 KKA01268.1 - 0.093 12.8 10.8 1.4 9.0 2.6 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KKA01268.1 - 3 7.9 15.6 0.69 9.9 3.0 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein ArAE_2 PF10334.9 KKA01269.1 - 5.4e-06 26.4 0.3 1.4e-05 25.1 0.3 1.7 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KKA01269.1 - 0.0043 17.2 7.3 0.0043 17.2 7.3 3.1 2 2 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 KKA01269.1 - 0.0067 15.5 14.2 0.026 13.6 0.2 2.9 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal Pox_H7 PF04787.12 KKA01269.1 - 0.21 12.1 0.1 0.21 12.1 0.1 2.9 2 1 1 3 3 3 0 Late protein H7 MFS_1 PF07690.16 KKA01270.1 - 1.4e-26 93.2 11.8 1.4e-26 93.2 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKA01270.1 - 3.9e-08 32.6 0.0 5.2e-05 22.3 0.0 2.7 1 1 2 3 3 3 2 MFS_1 like family Nuc_H_symport PF03825.16 KKA01270.1 - 0.00047 19.3 3.9 0.00047 19.3 3.9 2.1 2 0 0 2 2 2 1 Nucleoside H+ symporter ATG22 PF11700.8 KKA01270.1 - 0.0023 16.6 16.1 0.0055 15.4 6.3 2.8 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like Y_phosphatase PF00102.27 KKA01271.1 - 1.5e-53 181.8 9.6 1.8e-53 181.5 6.1 2.6 2 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 KKA01271.1 - 0.00042 20.1 0.1 0.00042 20.1 0.1 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KKA01271.1 - 0.0012 19.0 0.0 0.0056 16.8 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KKA01271.1 - 0.0015 18.6 0.1 0.0072 16.3 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family HSP70 PF00012.20 KKA01272.1 - 7.8e-228 757.5 12.7 8.7e-228 757.4 12.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKA01272.1 - 2.6e-16 59.3 4.1 1.5e-15 56.8 0.4 2.4 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KKA01272.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KKA01272.1 - 0.033 13.5 0.2 0.033 13.5 0.2 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KKA01272.1 - 0.095 12.2 2.2 0.49 9.8 0.3 2.8 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family ATP-synt_E PF05680.12 KKA01272.1 - 0.57 10.6 4.8 1.3 9.4 2.5 2.5 2 0 0 2 2 2 0 ATP synthase E chain FtsA PF14450.6 KKA01272.1 - 0.66 10.4 9.7 9.8 6.7 0.1 3.7 3 2 0 3 3 3 0 Cell division protein FtsA RIO1 PF01163.22 KKA01273.1 - 5.5e-43 146.8 1.2 9.8e-43 145.9 1.2 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KKA01273.1 - 7e-26 90.3 0.3 2.1e-25 88.8 0.1 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KKA01273.1 - 0.00011 22.2 0.2 0.63 9.9 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KKA01273.1 - 0.00081 18.8 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKA01273.1 - 0.067 12.6 1.5 0.15 11.4 0.7 1.9 2 0 0 2 2 2 0 Protein kinase domain PH_18 PF18469.1 KKA01274.1 - 7.8e-30 103.7 4.1 7.8e-30 103.7 4.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 KKA01274.1 - 2.2e-26 92.1 1.9 3.5e-26 91.4 0.3 2.3 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DEK_C PF08766.11 KKA01274.1 - 0.46 10.5 3.7 1.8 8.6 0.1 3.3 3 0 0 3 3 3 0 DEK C terminal domain Peptidase_S10 PF00450.22 KKA01275.1 - 2.1e-104 350.3 6.8 2.6e-104 350.0 6.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Mito_carr PF00153.27 KKA01277.1 - 1.2e-59 198.3 0.3 1.8e-20 72.6 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.19 KKA01278.1 - 5.1e-126 419.9 0.0 6.6e-126 419.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKA01278.1 - 3.1e-51 173.7 0.0 5e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KKA01278.1 - 0.025 15.2 0.1 0.052 14.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KKA01278.1 - 0.056 12.8 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 KKA01278.1 - 0.057 13.7 0.0 0.23 11.7 0.0 2.1 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase XPG_I PF00867.18 KKA01280.1 - 5.2e-27 94.0 0.7 5.2e-26 90.8 0.0 3.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KKA01280.1 - 7.8e-27 93.7 0.0 2.5e-26 92.1 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KKA01280.1 - 0.00095 19.7 0.0 0.011 16.4 0.0 2.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KKA01280.1 - 0.016 15.8 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.16 KKA01280.1 - 0.016 15.1 0.5 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain V-SNARE PF05008.15 KKA01280.1 - 0.042 14.2 4.3 5.2 7.5 0.2 4.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus HHH_2 PF12826.7 KKA01280.1 - 0.05 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif TetR PF13972.6 KKA01280.1 - 0.061 13.0 0.6 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Bacterial transcriptional repressor Transposase_20 PF02371.16 KKA01280.1 - 0.2 12.0 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family TMEM252 PF15664.5 KKA01280.1 - 5.5 6.7 8.4 1.7 8.4 1.4 2.5 2 0 0 2 2 2 0 Transmembrane protein 252 family Nodulin-like PF06813.13 KKA01281.1 - 0.005 16.4 8.2 0.005 16.4 8.2 1.3 1 1 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KKA01281.1 - 0.024 13.6 15.0 0.004 16.1 10.6 1.7 1 1 1 2 2 2 0 Major Facilitator Superfamily Clat_adaptor_s PF01217.20 KKA01281.1 - 0.052 13.5 0.6 0.1 12.6 0.6 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain E1-E2_ATPase PF00122.20 KKA01281.1 - 0.16 11.5 0.5 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase SecY PF00344.20 KKA01283.1 - 4.2e-58 197.0 17.2 5.4e-58 196.7 17.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KKA01283.1 - 9.9e-15 54.1 0.1 4e-14 52.1 0.1 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p tRNA-synt_1 PF00133.22 KKA01284.1 - 7.7e-46 156.5 7.1 1.9e-17 62.8 0.4 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KKA01284.1 - 2.2e-30 105.6 0.1 4.6e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KKA01284.1 - 4.3e-29 101.5 0.1 1.8e-19 69.7 0.0 4.5 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKA01284.1 - 1.2e-05 25.3 0.3 3.2e-05 23.9 0.3 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zinc_ribbon_15 PF17032.5 KKA01284.1 - 0.059 14.1 0.4 0.17 12.7 0.4 1.7 1 0 0 1 1 1 0 zinc-ribbon family DUF5485 PF17586.2 KKA01284.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5485) zf-ACC PF17848.1 KKA01284.1 - 0.96 9.6 5.1 1.6 8.9 0.9 2.7 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KKA01284.1 - 0.99 8.9 6.1 14 5.2 2.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CRAL_TRIO PF00650.20 KKA01285.1 - 8e-44 149.2 0.1 1.3e-43 148.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKA01285.1 - 1.2e-08 35.0 0.1 4.2e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKA01285.1 - 6.4e-06 26.4 0.1 1.1e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CPDase PF07823.11 KKA01286.1 - 3.5e-21 75.8 0.0 5.5e-21 75.2 0.0 1.3 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein Prophage_tail PF06605.11 KKA01286.1 - 0.0067 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Prophage endopeptidase tail Dus PF01207.17 KKA01287.1 - 2.6e-53 181.2 0.0 3.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-H2C2_2 PF13465.6 KKA01288.1 - 6.2e-07 29.6 15.3 1.8e-05 24.9 3.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKA01288.1 - 1e-06 28.9 10.2 0.00091 19.6 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKA01288.1 - 0.00021 21.8 9.8 0.091 13.7 1.7 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger Cys_Met_Meta_PP PF01053.20 KKA01289.1 - 1.4e-14 53.5 0.0 2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PA PF02225.22 KKA01290.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 PA domain DUF4488 PF14869.6 KKA01290.1 - 0.02 14.8 0.7 0.091 12.7 0.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) ENTH PF01417.20 KKA01291.1 - 8.7e-45 151.8 0.1 1.6e-44 151.0 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KKA01291.1 - 0.013 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 ANTH domain DSS1_SEM1 PF05160.13 KKA01291.1 - 0.015 15.3 0.3 4.3 7.5 0.1 2.8 2 0 0 2 2 2 0 DSS1/SEM1 family DGF-1_C PF11040.8 KKA01291.1 - 0.023 14.7 7.9 0.22 11.5 0.6 3.1 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Aldedh PF00171.22 KKA01293.1 - 1.9e-161 537.7 0.0 2.2e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKA01293.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NIF PF03031.18 KKA01295.1 - 6.2e-33 113.8 0.8 1e-32 113.0 0.8 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MotA_ExbB PF01618.16 KKA01295.1 - 0.031 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family LMBR1 PF04791.16 KKA01295.1 - 0.41 9.5 13.8 0.18 10.6 2.0 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF496 PF04363.12 KKA01295.1 - 3.4 7.8 10.0 0.19 11.8 0.5 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF496) RNA_pol_Rpb2_6 PF00562.28 KKA01296.1 - 3.6e-125 418.1 1.0 4.5e-125 417.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKA01296.1 - 1.1e-59 201.3 1.3 1.7e-59 200.7 1.3 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKA01296.1 - 2.2e-35 122.0 2.2 7.2e-35 120.3 2.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKA01296.1 - 4.9e-33 113.4 0.2 1.6e-32 111.8 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KKA01296.1 - 7.7e-27 93.4 0.7 2.5e-26 91.8 0.4 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KKA01296.1 - 2.3e-18 66.1 0.0 5.9e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KKA01296.1 - 2.8e-11 43.8 0.4 9.1e-11 42.2 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF370 PF04025.12 KKA01296.1 - 0.11 12.7 0.9 0.28 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF370) TruD PF01142.18 KKA01297.1 - 1e-69 235.4 1.7 1.7e-61 208.3 0.0 3.1 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) WD40 PF00400.32 KKA01298.1 - 1.3e-17 63.8 6.0 0.00038 21.2 0.1 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 KKA01298.1 - 0.0086 16.1 0.4 7.8 6.6 0.0 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region MOZ_SAS PF01853.18 KKA01299.1 - 1.9e-79 265.5 0.2 3e-79 264.8 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKA01299.1 - 2e-18 65.7 0.1 5.4e-18 64.4 0.1 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KKA01299.1 - 7.8e-16 57.7 0.5 1.7e-15 56.6 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 KKA01299.1 - 0.0001 22.5 0.0 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKA01299.1 - 0.00017 22.0 0.0 0.00046 20.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 KKA01299.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_10 PF13673.7 KKA01299.1 - 0.067 13.1 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF5101 PF17031.5 KKA01299.1 - 3.5 7.8 5.6 10 6.3 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5101) PTPA PF03095.15 KKA01300.1 - 2.1e-110 368.9 0.3 2.5e-110 368.7 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.13 KKA01301.1 - 5.2e-75 252.1 1.1 2.5e-74 249.9 1.1 1.8 1 1 0 1 1 1 1 Diacylglycerol acyltransferase LicD PF04991.13 KKA01302.1 - 6.6e-16 59.1 11.0 6.6e-16 59.1 11.0 4.4 2 2 3 5 5 5 3 LicD family Asp PF00026.23 KKA01303.1 - 1.7e-102 343.1 0.2 2.1e-102 342.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKA01303.1 - 7.5e-14 52.4 0.9 2e-12 47.7 0.9 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKA01303.1 - 0.027 15.1 0.2 18 6.0 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease Methyltransf_15 PF09445.10 KKA01304.1 - 7.4e-32 110.2 0.2 1.9e-31 108.9 0.2 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KKA01304.1 - 7.8e-05 23.3 0.0 0.00024 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKA01304.1 - 0.0013 18.3 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KKA01304.1 - 0.0089 16.0 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKA01304.1 - 0.067 12.6 0.1 0.26 10.6 0.0 2.0 2 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KKA01304.1 - 0.1 13.3 0.0 0.29 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KKA01305.1 - 3.9e-66 223.1 0.1 4.2e-62 209.9 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01305.1 - 2e-34 119.0 0.1 1.4e-33 116.3 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KKA01305.1 - 4.2e-06 26.5 0.1 0.0016 18.1 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKA01305.1 - 6.3e-05 22.4 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKA01305.1 - 0.00027 19.8 0.4 0.0035 16.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KKA01305.1 - 0.0024 16.9 4.9 0.0068 15.4 1.2 2.7 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KKA01305.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKA01305.1 - 0.25 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family VLPT PF07122.11 KKA01305.1 - 0.29 10.9 4.0 0.81 9.5 4.0 1.7 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) GrpE PF01025.19 KKA01306.1 - 3.2e-45 153.8 11.5 7.3e-45 152.6 11.1 1.7 1 1 1 2 2 2 1 GrpE Peptidase_S49 PF01343.18 KKA01306.1 - 0.0023 17.9 1.1 0.0068 16.4 0.3 2.1 2 1 0 2 2 2 1 Peptidase family S49 G_path_suppress PF15991.5 KKA01306.1 - 0.15 12.2 11.4 0.21 11.7 11.4 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor ABC1 PF03109.16 KKA01306.1 - 1.2 9.3 6.5 3 8.0 2.3 2.2 2 0 0 2 2 2 0 ABC1 family Pkinase PF00069.25 KKA01307.1 - 3.4e-61 206.9 0.0 1.4e-58 198.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01307.1 - 4.2e-35 121.3 0.0 4e-33 114.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA01307.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKA01307.1 - 0.032 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L35Ae PF01247.18 KKA01308.1 - 5.6e-41 138.6 1.3 6.3e-41 138.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KKA01308.1 - 0.0058 16.8 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain CagA PF03507.13 KKA01309.1 - 0.12 12.3 0.3 2.1 8.2 0.3 2.0 1 1 1 2 2 2 0 CagA exotoxin DHFR_1 PF00186.19 KKA01310.1 - 3.4e-30 104.9 0.0 5.4e-30 104.2 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase PRKCSH_1 PF13015.6 KKA01310.1 - 0.018 14.7 0.5 0.034 13.8 0.5 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein K_trans PF02705.16 KKA01311.1 - 1.9e-157 525.1 23.4 2.5e-157 524.6 23.4 1.1 1 0 0 1 1 1 1 K+ potassium transporter AA_permease PF00324.21 KKA01312.1 - 1.4e-136 455.9 33.5 1.8e-136 455.5 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA01312.1 - 2.6e-32 112.2 33.9 3.5e-32 111.8 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease Clp1 PF06807.14 KKA01313.1 - 5e-15 56.0 0.8 2.2e-14 53.9 0.1 2.4 2 1 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_P PF16575.5 KKA01313.1 - 1.1e-13 51.5 0.1 8.8e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KKA01313.1 - 1.2e-10 41.4 0.0 2.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor FtsK_SpoIIIE PF01580.18 KKA01313.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KKA01313.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KKA01313.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AA_permease PF00324.21 KKA01314.1 - 3.9e-137 457.7 35.0 4.8e-137 457.4 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA01314.1 - 8.5e-33 113.8 33.9 1.1e-32 113.4 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 KKA01314.1 - 2.6 8.5 6.3 9.7 6.7 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) MutL_C PF08676.11 KKA01316.1 - 9.4e-13 48.2 0.3 3e-12 46.5 0.2 1.8 1 1 1 2 2 2 1 MutL C terminal dimerisation domain PP1_inhibitor PF05361.12 KKA01316.1 - 0.024 14.6 1.9 0.031 14.3 0.4 2.0 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor COX2 PF00116.20 KKA01316.1 - 0.14 12.0 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, periplasmic domain Oxysterol_BP PF01237.18 KKA01317.1 - 4.4e-61 206.8 7.4 6.3e-59 199.7 7.4 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Methyltransf_24 PF13578.6 KKA01317.1 - 0.15 13.1 0.0 0.27 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.20 KKA01318.1 - 2e-15 57.2 0.0 1.7e-07 31.7 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain DNA_pol_B PF00136.21 KKA01319.1 - 1.1e-87 294.6 8.4 1.1e-87 294.6 8.4 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKA01319.1 - 5.1e-24 85.0 28.5 2.1e-16 60.0 11.6 3.6 2 2 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKA01319.1 - 2.5e-06 27.8 8.6 7.7e-06 26.3 8.6 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Mob_synth_C PF06463.13 KKA01319.1 - 0.092 12.7 0.6 0.37 10.7 0.6 2.1 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Tma16 PF11176.8 KKA01320.1 - 7.8e-43 145.9 7.4 9.1e-43 145.6 7.4 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 PDGF_N PF04692.13 KKA01320.1 - 0.55 11.1 3.8 0.32 11.8 0.8 2.0 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region ACPS PF01648.20 KKA01322.1 - 2.8e-14 53.2 0.0 3.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily STIMATE PF12400.8 KKA01323.1 - 2.5e-28 99.1 5.8 2.5e-28 99.1 5.8 1.7 2 0 0 2 2 2 1 STIMATE family DNA_mis_repair PF01119.19 KKA01323.1 - 0.086 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain SieB PF14163.6 KKA01323.1 - 9.6 5.7 11.2 0.51 9.8 0.8 3.0 3 1 1 4 4 4 0 Super-infection exclusion protein B EF-G-binding_N PF07299.11 KKA01324.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.5 5 1 0 5 5 5 0 Elongation factor G-binding protein, N-terminal adh_short PF00106.25 KKA01325.1 - 2.4e-09 37.0 0.0 2.7e-05 23.7 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKA01325.1 - 0.00039 20.0 0.0 0.0047 16.5 0.0 2.3 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase CHORD PF04968.12 KKA01325.1 - 0.13 13.1 0.2 0.29 11.9 0.2 1.6 1 0 0 1 1 1 0 CHORD tRNA-synt_1 PF00133.22 KKA01326.1 - 4.6e-46 157.3 1.6 4.2e-37 127.7 0.5 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKA01326.1 - 1.1e-16 60.5 6.5 5.6e-10 38.5 0.1 4.9 3 1 0 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKA01326.1 - 1.3e-12 48.0 0.0 4.6e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KKA01326.1 - 3.6e-08 33.1 1.0 7e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain GLEYA PF10528.9 KKA01328.1 - 2e-15 57.0 2.9 2e-15 57.0 2.9 2.7 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.12 KKA01328.1 - 1e-08 35.1 0.1 3e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 PA14 domain RSN1_7TM PF02714.15 KKA01329.1 - 4.4e-84 282.1 22.3 4.4e-84 282.1 22.3 2.5 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKA01329.1 - 1.1e-40 139.0 6.6 1.1e-40 139.0 6.6 2.2 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKA01329.1 - 1.2e-22 81.0 3.5 2.4e-22 80.0 3.5 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKA01329.1 - 2.3e-11 43.7 0.1 2.3e-11 43.7 0.1 2.6 3 1 0 3 3 3 1 Extracellular tail, of 10TM putative phosphate transporter ZZ PF00569.17 KKA01330.1 - 4.3e-07 29.6 13.2 1.1e-06 28.3 13.2 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KKA01330.1 - 0.00016 21.9 10.9 0.00054 20.2 10.9 1.9 1 0 0 1 1 1 1 C1 domain Alpha-amylase_N PF02903.14 KKA01330.1 - 0.12 12.5 0.5 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Alpha amylase, N-terminal ig-like domain eRF1_2 PF03464.15 KKA01331.1 - 7.1e-47 159.1 0.0 1.4e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KKA01331.1 - 6e-38 129.8 0.3 1.3e-37 128.7 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KKA01331.1 - 9.3e-18 64.5 0.0 1.7e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KKA01331.1 - 1.7e-10 41.3 0.0 2.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KKA01331.1 - 1.6e-07 31.7 0.0 2.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 PTSIIB_sorb PF03830.15 KKA01331.1 - 0.059 13.6 0.3 1.5 9.0 0.0 2.6 2 1 0 2 2 2 0 PTS system sorbose subfamily IIB component p450 PF00067.22 KKA01332.1 - 1.1e-39 136.5 1.2 6.1e-34 117.5 0.2 2.1 1 1 1 2 2 2 2 Cytochrome P450 DEAD PF00270.29 KKA01333.1 - 1.1e-36 126.2 0.3 2.8e-36 124.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA01333.1 - 8.4e-29 100.2 1.8 3.3e-26 91.8 0.1 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Vps35 PF03635.17 KKA01334.1 - 4.3e-125 418.9 49.0 5.7e-125 418.6 49.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 ATG11 PF10377.9 KKA01334.1 - 0.19 11.8 3.6 1.1 9.3 0.1 3.6 3 1 0 3 3 3 0 Autophagy-related protein 11 IBV_3A PF03617.13 KKA01334.1 - 0.49 10.4 0.0 0.49 10.4 0.0 4.6 4 0 0 4 4 4 0 IBV 3A protein 6PF2K PF01591.18 KKA01335.1 - 3.1e-50 170.6 7.2 5.4e-50 169.8 7.2 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKA01335.1 - 6.4e-38 130.4 0.0 9.8e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KKA01335.1 - 2e-05 24.2 0.7 6.9e-05 22.4 0.7 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KKA01335.1 - 0.0042 17.3 0.0 0.0073 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DBD_HTH PF18430.1 KKA01335.1 - 0.14 12.0 2.3 0.15 11.9 0.5 2.0 2 0 0 2 2 2 0 Putative DNA-binding domain Peptidase_S64 PF08192.11 KKA01336.1 - 2e-186 621.6 18.3 2.4e-186 621.3 18.3 1.0 1 0 0 1 1 1 1 Peptidase family S64 NAD_binding_1 PF00175.21 KKA01338.1 - 8.1e-15 55.4 0.0 2.7e-14 53.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKA01338.1 - 2.3e-14 53.5 0.0 1.5e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKA01338.1 - 4e-07 30.3 0.2 3.8e-06 27.1 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain LPD3 PF18798.1 KKA01338.1 - 0.054 13.7 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 UIM PF02809.20 KKA01339.1 - 0.012 15.5 3.7 0.012 15.5 3.7 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif Peptidase_C74 PF12387.8 KKA01339.1 - 0.016 14.7 1.1 0.37 10.2 0.1 2.6 2 0 0 2 2 2 0 Pestivirus NS2 peptidase RAP80_UIM PF18282.1 KKA01339.1 - 0.18 11.6 3.1 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif F-box-like PF12937.7 KKA01340.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like ALO PF04030.14 KKA01341.1 - 3.3e-95 318.8 2.5 4.3e-95 318.4 2.5 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KKA01341.1 - 1.6e-26 92.7 0.0 2.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SIS_2 PF13580.6 KKA01341.1 - 0.088 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 SIS domain RRM_1 PF00076.22 KKA01342.1 - 1.5e-16 60.0 10.8 2e-06 27.5 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKA01342.1 - 1.2e-11 44.3 0.2 1.5e-07 31.1 0.0 3.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KKA01342.1 - 0.011 15.3 1.3 0.14 11.8 0.6 2.5 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 KKA01343.1 - 0.0062 16.4 2.2 0.0089 15.9 0.1 2.4 2 1 1 3 3 3 1 G-patch domain V-ATPase_G PF03179.15 KKA01344.1 - 0.0093 16.5 6.7 0.021 15.3 6.7 1.6 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_E_2 PF08112.11 KKA01344.1 - 0.31 11.4 13.7 0.21 11.9 1.7 3.9 2 1 1 3 3 3 0 ATP synthase epsilon subunit LMBR1 PF04791.16 KKA01344.1 - 1.5 7.6 7.2 1.7 7.4 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Sugar_tr PF00083.24 KKA01345.1 - 4.8e-38 131.2 19.1 8e-38 130.5 19.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA01345.1 - 4.8e-22 78.4 21.3 4.8e-22 78.4 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HECT PF00632.25 KKA01346.1 - 2.1e-42 145.7 6.0 4.4e-42 144.6 6.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NADH_B2 PF14813.6 KKA01346.1 - 0.046 13.5 0.3 0.35 10.7 0.2 2.3 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 IQ PF00612.27 KKA01346.1 - 0.054 13.3 1.0 0.14 12.0 1.0 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif RSN1_7TM PF02714.15 KKA01347.1 - 8.5e-91 304.1 26.8 8.5e-91 304.1 26.8 2.5 3 1 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKA01347.1 - 4.6e-36 123.9 4.2 4.6e-36 123.9 4.2 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKA01347.1 - 4.5e-27 95.4 3.5 7.8e-27 94.6 3.5 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKA01347.1 - 8.7e-16 57.9 0.0 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Insulin_TMD PF17870.1 KKA01347.1 - 0.066 13.3 0.3 0.066 13.3 0.3 4.0 4 0 0 4 4 4 0 Insulin receptor trans-membrane segment Pyrophosphatase PF00719.19 KKA01348.1 - 6.5e-49 165.8 0.2 6.5e-49 165.8 0.2 1.6 2 0 0 2 2 2 1 Inorganic pyrophosphatase PdaC PF13739.6 KKA01348.1 - 0.46 11.5 8.2 2.3 9.3 1.9 3.0 3 0 0 3 3 3 0 Deacetylase PdaC Tubulin PF00091.25 KKA01349.1 - 3.5e-65 219.9 0.0 4.9e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKA01349.1 - 1.4e-47 160.9 0.0 2.5e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KKA01349.1 - 0.028 14.1 0.0 0.13 11.9 0.0 2.1 1 1 1 2 2 2 0 Tubulin domain HMG_CoA_synt_C PF08540.10 KKA01350.1 - 5.9e-108 360.7 1.3 8.2e-108 360.3 1.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KKA01350.1 - 3e-89 297.5 0.9 3e-89 297.5 0.9 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RPM2 PF08579.11 KKA01351.1 - 2.3e-29 102.2 3.9 2.3e-29 102.2 3.9 3.6 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 KKA01351.1 - 4.8e-07 29.9 0.2 4e-06 26.9 0.1 2.7 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 KKA01351.1 - 0.011 15.8 3.0 0.021 14.9 0.2 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 KKA01351.1 - 0.089 12.5 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 PPR repeat Phage_TAC_4 PF08748.11 KKA01351.1 - 1.5 9.2 6.2 2.2 8.6 1.5 2.8 2 0 0 2 2 2 0 Phage tail assembly chaperone Ish1 PF10281.9 KKA01353.1 - 8.4e-14 51.6 76.5 3.8e-08 33.5 8.3 11.6 11 2 0 11 11 11 6 Putative stress-responsive nuclear envelope protein SecA_SW PF07516.13 KKA01353.1 - 0.013 15.5 2.9 0.013 15.5 2.9 3.1 1 1 1 2 2 2 0 SecA Wing and Scaffold domain GnsAB_toxin PF08178.11 KKA01353.1 - 0.026 14.5 0.6 1 9.3 0.0 3.1 3 0 0 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Apolipoprotein PF01442.18 KKA01353.1 - 0.044 13.7 2.6 0.11 12.3 0.6 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DinB_2 PF12867.7 KKA01353.1 - 0.098 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily DUF883 PF05957.13 KKA01353.1 - 0.16 12.6 8.0 11 6.7 0.3 4.2 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) FliG_C PF01706.16 KKA01353.1 - 0.17 12.1 1.9 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 FliG C-terminal domain MscS_porin PF12795.7 KKA01353.1 - 2.6 7.5 11.3 1.1 8.8 2.5 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Isochorismatase PF00857.20 KKA01353.1 - 3.1 7.9 6.0 20 5.3 0.1 3.6 3 1 1 4 4 4 0 Isochorismatase family zf_CCCH_4 PF18345.1 KKA01354.1 - 0.00014 21.8 8.8 0.011 15.8 2.2 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KKA01354.1 - 0.00022 21.0 5.5 0.0091 15.9 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KKA01354.1 - 0.0027 17.5 0.4 0.0052 16.6 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 KKA01354.1 - 0.028 14.2 5.9 0.029 14.2 1.6 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 KKA01354.1 - 1.5 9.6 6.7 0.31 11.7 0.5 2.3 3 0 0 3 3 3 0 Torus domain Proteasome PF00227.26 KKA01355.1 - 8.9e-60 201.4 0.0 1.1e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKA01355.1 - 3e-08 33.2 0.1 3e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Utp14 PF04615.13 KKA01356.1 - 2.5e-177 591.8 86.2 2.5e-177 591.8 86.2 2.8 1 1 2 3 3 3 1 Utp14 protein COA2 PF17051.5 KKA01356.1 - 0.1 12.7 1.5 0.37 10.9 1.5 2.0 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 TFIID-18kDa PF02269.16 KKA01357.1 - 6.7e-08 32.4 3.4 7.4e-06 25.9 3.4 2.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF4407 PF14362.6 KKA01357.1 - 1.5 8.1 4.1 2.5 7.4 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KKA01357.1 - 2.2 8.5 10.6 0.24 11.6 4.8 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family hNIFK_binding PF12196.8 KKA01357.1 - 8.3 6.0 7.6 13 5.4 6.3 2.0 1 1 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Rad10 PF03834.14 KKA01358.1 - 6.6e-33 113.1 1.9 1.1e-32 112.4 1.9 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF5521 PF17659.1 KKA01358.1 - 0.0057 14.6 0.2 0.0059 14.5 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5521) Haemagg_act PF05860.13 KKA01358.1 - 0.26 11.2 3.0 0.52 10.2 2.8 1.6 1 1 0 1 1 1 0 haemagglutination activity domain Asn_synthase PF00733.21 KKA01359.1 - 1.9e-20 73.9 0.2 4.5e-09 36.4 0.0 2.6 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KKA01359.1 - 2.6e-10 40.3 0.1 5.9e-09 35.9 0.1 3.0 2 1 1 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKA01359.1 - 3.4e-05 24.1 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKA01359.1 - 0.049 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein ERO1 PF04137.15 KKA01360.1 - 2.2e-112 375.8 0.3 2.2e-112 375.8 0.3 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DREV PF05219.12 KKA01360.1 - 0.0018 17.4 0.2 1.5 7.9 0.1 2.4 2 0 0 2 2 2 2 DREV methyltransferase Zn_clus PF00172.18 KKA01361.1 - 9.1e-07 28.9 8.8 1.6e-06 28.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pim PF16765.5 KKA01361.1 - 0.023 14.8 0.4 0.079 13.1 0.4 1.9 1 0 0 1 1 1 0 Pesticin immunity protein NINJA_B PF16136.5 KKA01361.1 - 0.04 14.3 2.4 0.088 13.2 2.4 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal PRF PF06875.11 KKA01361.1 - 0.28 10.6 3.2 0.37 10.2 0.2 2.6 2 1 1 3 3 3 0 Plethodontid receptivity factor PRF GFO_IDH_MocA PF01408.22 KKA01362.1 - 1.1e-21 77.9 0.0 1.8e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKA01362.1 - 0.00038 20.5 0.0 0.00068 19.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KKA01362.1 - 0.0015 19.2 0.0 0.0027 18.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 KKA01362.1 - 0.16 12.7 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Mannosyl_trans3 PF11051.8 KKA01363.1 - 7e-79 265.0 0.0 1.2e-78 264.3 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative DUF4806 PF16064.5 KKA01363.1 - 0.12 12.6 0.6 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Spt20 PF12090.8 KKA01364.1 - 1.3e-19 70.8 17.8 1.8e-11 44.1 1.1 3.9 3 1 1 4 4 4 2 Spt20 family CAMSAP_CH PF11971.8 KKA01364.1 - 0.75 9.7 3.8 5.3 7.0 0.0 3.1 3 1 0 4 4 4 0 CAMSAP CH domain LRR_6 PF13516.6 KKA01365.1 - 0.034 14.2 14.8 1 9.6 0.1 6.0 7 0 0 7 7 7 0 Leucine Rich repeat Nop PF01798.18 KKA01366.1 - 1e-83 280.4 0.4 2.6e-83 279.0 0.4 1.7 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKA01366.1 - 1.2e-20 73.6 0.9 3.4e-20 72.2 0.1 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain UBD PF16455.5 KKA01366.1 - 0.16 12.3 0.5 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-binding domain WD40 PF00400.32 KKA01367.1 - 6.5e-10 39.4 1.1 0.0001 23.0 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KKA01367.1 - 0.00063 20.2 0.0 0.042 14.4 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain WD40_like PF17005.5 KKA01367.1 - 0.0019 17.6 0.1 0.0072 15.7 0.0 1.9 1 1 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 KKA01367.1 - 0.0027 17.9 0.1 4.7 7.6 0.1 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NMT PF01233.19 KKA01368.1 - 6.1e-67 224.4 0.8 1.3e-66 223.4 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 KKA01368.1 - 1e-44 152.6 5.9 1e-44 152.6 5.9 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 KKA01368.1 - 0.0023 18.1 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family AsmA_1 PF13109.6 KKA01368.1 - 0.0024 17.4 0.4 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 AsmA-like C-terminal region PRELI PF04707.14 KKA01369.1 - 2.1e-19 69.9 4.8 2.6e-18 66.3 4.8 2.0 1 1 0 1 1 1 1 PRELI-like family GATase_2 PF00310.21 KKA01370.1 - 4.8e-163 542.8 0.0 8.6e-163 541.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KKA01370.1 - 2e-144 481.3 0.0 4.1e-144 480.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KKA01370.1 - 3.8e-104 348.1 0.3 2.9e-102 341.9 0.1 2.4 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KKA01370.1 - 2.5e-71 239.2 1.1 4.1e-71 238.5 0.3 1.8 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.6 KKA01370.1 - 9.5e-24 83.4 0.1 2.3e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KKA01370.1 - 2.3e-22 79.6 0.8 1.5e-21 76.9 0.8 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKA01370.1 - 1.7e-08 34.9 0.7 0.00013 22.5 0.0 4.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKA01370.1 - 4.8e-08 33.1 0.0 2e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKA01370.1 - 7.6e-06 25.5 0.0 2.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KKA01370.1 - 8.1e-05 22.0 0.4 0.1 11.8 0.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKA01370.1 - 0.00011 21.9 3.1 0.0019 17.8 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKA01370.1 - 0.00015 21.3 0.0 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKA01370.1 - 0.00061 18.6 2.0 0.00069 18.4 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KKA01370.1 - 0.0021 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KKA01370.1 - 0.0025 18.2 1.5 1.2 9.6 0.0 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KKA01370.1 - 0.0028 17.0 0.4 0.41 10.0 0.0 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KKA01370.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KKA01370.1 - 0.015 14.6 0.3 0.057 12.7 0.1 2.1 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 KKA01370.1 - 0.022 13.2 0.1 0.38 9.1 0.0 2.2 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 KKA01370.1 - 0.022 14.7 0.0 0.069 13.1 0.0 1.9 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.6 KKA01370.1 - 0.066 13.4 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 1 0 Glutamine amidotransferase domain IlvN PF07991.12 KKA01370.1 - 0.14 11.7 1.1 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KKA01370.1 - 0.19 11.8 6.1 4.1 7.5 0.1 3.4 4 0 0 4 4 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KKA01370.1 - 0.31 11.2 4.2 4.7 7.4 0.0 3.4 4 0 0 4 4 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KKA01370.1 - 1.2 8.4 7.6 5.4 6.2 0.1 2.9 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 KKA01370.1 - 5.3 7.7 7.3 3.9 8.1 0.0 3.9 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent eIF3_subunit PF08597.10 KKA01371.1 - 4.6e-44 151.1 15.3 5.8e-44 150.8 15.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SH3_9 PF14604.6 KKA01372.1 - 5.2e-08 32.6 0.0 8.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKA01372.1 - 6.9e-08 32.1 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKA01372.1 - 1.3e-07 31.1 0.1 2.9e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 SH3 domain Peroxin-13_N PF04088.13 KKA01372.1 - 2.9e-07 30.9 1.2 0.0033 17.7 0.4 2.3 1 1 1 2 2 2 2 Peroxin 13, N-terminal region SH3_3 PF08239.11 KKA01372.1 - 0.014 15.7 0.2 0.025 14.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain FlaC_arch PF05377.11 KKA01373.1 - 0.48 10.9 11.3 0.16 12.4 2.9 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4986 PF16375.5 KKA01373.1 - 4.6 8.0 5.3 5.5 7.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function PALP PF00291.25 KKA01374.1 - 3e-79 266.5 0.0 3.8e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KKA01374.1 - 3.9e-41 138.7 0.1 1e-26 92.5 0.0 3.2 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF881 PF05949.12 KKA01374.1 - 0.097 12.5 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) tRNA-synt_2b PF00587.25 KKA01375.1 - 1.2e-31 110.0 0.0 2.2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sec61_beta PF03911.16 KKA01376.1 - 2.6e-06 27.3 0.5 4.6e-06 26.6 0.3 1.5 2 0 0 2 2 2 1 Sec61beta family LPP20 PF02169.16 KKA01376.1 - 0.033 14.5 0.7 0.042 14.2 0.7 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein TPR_2 PF07719.17 KKA01377.1 - 2.6e-13 49.0 0.2 0.018 15.1 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKA01377.1 - 5.6e-12 44.9 1.8 0.0017 18.1 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKA01377.1 - 1.2e-08 35.1 0.3 0.0028 17.9 0.0 4.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKA01377.1 - 2.7e-08 33.4 4.6 3 8.3 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKA01377.1 - 8.6e-07 28.6 0.0 1.4 9.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKA01377.1 - 2e-05 25.0 0.0 0.4 11.6 0.0 4.3 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKA01377.1 - 3.3e-05 24.0 2.4 0.52 10.8 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKA01377.1 - 0.00047 19.9 0.0 2.2 8.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKA01377.1 - 0.0026 18.3 0.0 4.7 8.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKA01377.1 - 0.012 15.3 3.7 1.4 8.6 0.0 3.8 3 1 1 4 4 4 0 TPR repeat TPR_16 PF13432.6 KKA01377.1 - 0.2 12.4 0.0 1 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PH PF00169.29 KKA01380.1 - 5.9e-15 55.7 0.1 1.6e-14 54.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKA01380.1 - 1.5e-08 35.0 0.3 1.5e-08 35.0 0.3 3.2 3 1 0 3 3 3 1 Pleckstrin homology domain SH3_9 PF14604.6 KKA01380.1 - 3.8e-07 29.9 0.0 7.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKA01380.1 - 1.7e-06 27.5 1.7 1.7e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.17 KKA01380.1 - 3.4e-05 23.9 0.1 0.00015 21.8 0.1 2.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKA01380.1 - 0.00065 20.1 0.2 0.0019 18.6 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_3 PF14593.6 KKA01380.1 - 0.03 14.4 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 PH domain NT-C2 PF10358.9 KKA01381.1 - 1.5e-16 60.4 16.0 1.5e-16 60.4 16.0 3.2 2 1 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C3HC4 PF00097.25 KKA01383.1 - 6.2e-09 35.6 8.5 9.6e-09 35.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKA01383.1 - 7e-09 35.4 6.4 1.2e-08 34.7 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKA01383.1 - 1.8e-08 34.1 6.7 2.7e-08 33.6 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKA01383.1 - 4.8e-07 30.0 6.6 7.8e-07 29.3 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKA01383.1 - 9.6e-07 28.7 3.2 6.7e-06 26.0 3.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKA01383.1 - 4.2e-06 26.6 8.9 6.8e-06 26.0 8.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKA01383.1 - 0.00013 21.7 5.4 0.00024 20.9 5.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKA01383.1 - 0.0018 18.4 7.3 0.0042 17.2 7.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KKA01383.1 - 0.017 14.9 7.1 0.18 11.6 4.6 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_14 PF17978.1 KKA01383.1 - 0.065 13.7 4.9 0.12 12.8 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KKA01383.1 - 0.087 13.1 7.3 0.37 11.1 7.1 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain IBR PF01485.21 KKA01383.1 - 0.37 11.1 8.2 0.32 11.2 5.7 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Elf1 PF05129.13 KKA01383.1 - 1.4 9.0 6.7 17 5.6 6.7 2.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-RING_4 PF14570.6 KKA01383.1 - 2.6 7.9 10.5 19 5.1 10.5 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PI3_PI4_kinase PF00454.27 KKA01385.1 - 3.5e-39 135.1 1.5 1.8e-38 132.8 1.5 2.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KKA01385.1 - 4.9e-08 32.7 0.1 1.1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain SH3_2 PF07653.17 KKA01386.1 - 1.8e-10 40.3 0.0 3.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKA01386.1 - 2.1e-09 36.8 0.6 9.6e-09 34.7 0.6 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKA01386.1 - 7.5e-08 32.1 0.8 9.8e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain TctB PF07331.11 KKA01386.1 - 0.037 14.3 1.4 0.054 13.8 1.4 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family G-gamma PF00631.22 KKA01387.1 - 4.9e-17 61.7 0.0 8.6e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 GGL domain CtnDOT_TraJ PF07863.11 KKA01387.1 - 0.029 15.0 0.4 0.064 13.9 0.4 1.6 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon JLPA PF16668.5 KKA01387.1 - 0.047 12.7 7.8 0.58 9.2 4.5 2.1 1 1 1 2 2 2 0 Adhesin from Campylobacter DUF2034 PF10356.9 KKA01387.1 - 0.049 13.0 0.3 0.058 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) FYVE_2 PF02318.16 KKA01387.1 - 0.06 13.6 0.2 0.082 13.1 0.2 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Evr1_Alr PF04777.13 KKA01388.1 - 5.7e-26 90.9 0.5 9.5e-26 90.2 0.5 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Pox_E10 PF04805.12 KKA01388.1 - 0.06 13.2 0.4 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 E10-like protein conserved region DNA_RNApol_7kD PF03604.13 KKA01388.1 - 0.32 10.7 2.9 0.75 9.5 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TIP41 PF04176.13 KKA01389.1 - 5.6e-28 97.6 15.3 1.1e-26 93.4 12.0 3.0 2 1 0 2 2 2 1 TIP41-like family PIN_5 PF08745.11 KKA01389.1 - 0.00083 18.8 1.4 0.0016 17.9 1.4 1.4 1 0 0 1 1 1 1 PINc domain ribonuclease eIF-5_eIF-2B PF01873.17 KKA01391.1 - 2.6e-34 117.6 1.2 3.4e-34 117.2 0.2 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 KKA01391.1 - 1.1e-18 67.1 0.6 1.1e-18 67.1 0.6 3.0 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon APG6_N PF17675.1 KKA01391.1 - 0.12 13.0 11.1 0.1 13.1 8.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PUF PF00806.19 KKA01393.1 - 9.9e-22 75.4 2.7 7.3e-06 25.4 0.1 6.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KKA01393.1 - 0.00022 21.0 0.0 0.0008 19.2 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.21 KKA01394.1 - 1.7e-29 103.0 0.0 2.6e-21 76.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family MFMR_assoc PF16596.5 KKA01396.1 - 0.037 14.5 0.5 0.052 14.0 0.5 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR Peptidase_M20 PF01546.28 KKA01397.1 - 1.6e-24 86.7 0.0 2.5e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKA01397.1 - 4.1e-09 36.3 0.0 9.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKA01397.1 - 3e-07 30.4 0.0 7.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Esterase PF00756.20 KKA01398.1 - 5.4e-35 121.2 0.0 6.3e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KKA01398.1 - 0.0015 18.0 0.0 0.0034 16.9 0.0 1.5 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KKA01398.1 - 0.0096 15.2 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKA01398.1 - 0.14 11.8 0.1 0.79 9.3 0.2 2.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Paf1 PF03985.13 KKA01399.1 - 3.5e-38 131.7 37.6 4e-37 128.2 37.6 2.0 1 1 0 1 1 1 1 Paf1 DUF3507 PF12015.8 KKA01400.1 - 1.5e-24 86.7 1.7 4.8e-24 85.1 1.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2076 PF09849.9 KKA01400.1 - 0.042 13.9 0.4 0.042 13.9 0.4 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3484 PF11983.8 KKA01400.1 - 1.2 10.3 8.4 0.12 13.6 0.9 3.3 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Dcc1 PF09724.9 KKA01401.1 - 4.5e-40 138.0 2.5 5.3e-40 137.7 2.5 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF2856 PF11043.8 KKA01401.1 - 0.037 14.1 0.3 1 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2856) TRAM_LAG1_CLN8 PF03798.16 KKA01402.1 - 1e-27 97.2 25.8 1e-27 97.2 25.8 1.8 2 0 0 2 2 2 1 TLC domain DUF5365 PF17326.2 KKA01402.1 - 0.011 16.1 0.1 0.023 15.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Peptidase_M48 PF01435.18 KKA01403.1 - 3.2e-40 138.0 0.1 6.7e-39 133.7 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KKA01403.1 - 7.4e-39 133.5 8.5 1.4e-38 132.6 8.5 1.5 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices PCI PF01399.27 KKA01404.1 - 2.5e-17 63.3 1.2 1.2e-16 61.1 0.7 2.5 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 KKA01404.1 - 3.2e-12 46.7 0.5 8.4e-12 45.3 0.5 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal CSN8_PSD8_EIF3K PF10075.9 KKA01404.1 - 0.0057 16.6 0.5 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family MKT1_N PF12247.8 KKA01404.1 - 0.072 13.5 0.1 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication JmjC PF02373.22 KKA01405.1 - 8.9e-28 97.0 2.7 3e-27 95.3 2.7 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KKA01405.1 - 0.00037 20.4 0.6 0.00037 20.4 0.6 2.3 2 0 0 2 2 2 1 jmjN domain Zf_RING PF16744.5 KKA01405.1 - 0.015 15.4 3.8 0.053 13.7 3.8 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KKA01405.1 - 0.017 15.0 8.5 0.017 15.0 8.5 3.5 3 0 0 3 3 3 0 PHD-finger Ilm1 PF10311.9 KKA01406.1 - 8.8e-08 32.0 13.9 0.00032 20.4 6.8 2.0 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 P5CR_dimer PF14748.6 KKA01407.1 - 2.5e-33 114.4 0.3 4.2e-33 113.7 0.3 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KKA01407.1 - 4.4e-10 40.0 0.5 2.1e-08 34.6 0.4 3.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KKA01407.1 - 0.025 14.2 1.1 0.077 12.6 1.1 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BPS PF08947.10 KKA01407.1 - 0.031 14.1 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 BPS (Between PH and SH2) ATP-synt_ab PF00006.25 KKA01408.1 - 1.2e-62 211.4 0.0 1.8e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKA01408.1 - 4.7e-24 84.7 1.3 4.7e-24 84.7 1.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KKA01408.1 - 0.0036 16.7 0.2 0.0062 15.9 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 KKA01408.1 - 0.0064 15.7 0.8 0.075 12.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain T3SS_ATPase_C PF18269.1 KKA01408.1 - 0.025 14.4 1.0 0.14 12.0 1.0 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA PF00004.29 KKA01408.1 - 0.034 14.6 0.0 0.67 10.4 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KKA01408.1 - 0.037 13.9 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KKA01408.1 - 0.044 13.7 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KKA01408.1 - 0.07 13.5 1.1 0.47 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKA01408.1 - 0.089 13.2 0.7 0.23 11.8 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KKA01408.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KKA01408.1 - 0.15 12.3 0.2 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_S7 PF00177.21 KKA01410.1 - 2.9e-34 117.9 2.3 3.9e-34 117.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DCP1 PF06058.13 KKA01411.1 - 2e-20 72.9 0.9 1e-19 70.5 0.9 2.1 1 1 0 1 1 1 1 Dcp1-like decapping family RNA_pol_Rpc82 PF05645.13 KKA01412.1 - 1.4e-14 54.5 0.3 2.3e-08 34.1 0.4 2.7 1 1 1 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KKA01412.1 - 9.2e-12 44.9 4.9 1.7e-11 44.0 0.2 3.0 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain EF-hand_7 PF13499.6 KKA01413.1 - 7.5e-06 26.3 3.3 0.00022 21.6 3.3 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KKA01413.1 - 1.7e-05 24.4 2.7 0.00029 20.5 0.8 3.1 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KKA01413.1 - 0.0011 18.4 8.9 0.0035 16.8 1.1 3.8 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 KKA01413.1 - 0.015 14.8 1.8 0.015 14.8 1.8 2.7 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 KKA01413.1 - 0.017 15.3 2.4 0.023 14.9 1.1 1.8 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_8 PF13833.6 KKA01413.1 - 0.44 10.4 5.5 10 6.1 0.4 3.9 3 2 0 3 3 3 0 EF-hand domain pair RNA_pol_Rpb6 PF01192.22 KKA01414.1 - 3.4e-14 52.5 0.1 6.2e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pyr_redox_2 PF07992.14 KKA01414.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TipE PF16972.5 KKA01414.1 - 0.5 9.5 4.1 0.52 9.4 4.1 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE O-antigen_lig PF13425.6 KKA01414.1 - 0.59 8.9 2.7 0.73 8.5 2.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein zf-C2H2 PF00096.26 KKA01415.1 - 7.7e-17 60.7 73.5 0.00017 21.8 5.6 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKA01415.1 - 7.4e-15 54.4 69.6 0.12 13.3 2.8 10.0 9 1 1 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 KKA01415.1 - 4.1e-08 33.4 40.0 0.18 12.3 1.7 8.8 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KKA01415.1 - 0.0036 17.7 0.9 0.0036 17.7 0.9 10.7 12 1 0 12 12 12 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 KKA01415.1 - 0.0036 17.6 33.8 0.19 12.1 4.4 5.3 2 1 2 5 5 5 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 KKA01415.1 - 0.019 15.6 36.8 0.051 14.2 0.3 6.9 4 2 3 7 7 7 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 KKA01415.1 - 0.022 15.1 57.1 0.031 14.6 8.7 6.7 1 1 3 5 5 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KKA01415.1 - 0.022 15.4 32.2 0.11 13.2 4.6 4.3 2 2 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KKA01415.1 - 0.029 14.7 4.0 0.029 14.7 4.0 6.5 4 3 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KKA01415.1 - 0.094 13.0 63.9 0.12 12.7 1.1 9.9 11 0 0 11 11 10 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKA01415.1 - 0.27 11.0 19.6 0.35 10.7 0.1 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_Hakai PF18408.1 KKA01415.1 - 0.96 9.2 0.0 0.96 9.2 0.0 5.3 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain Ogr_Delta PF04606.12 KKA01415.1 - 3.1 7.8 15.1 0.68 10.0 0.5 4.1 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger Sec23_trunk PF04811.15 KKA01416.1 - 1.1e-66 224.9 0.0 1.9e-66 224.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KKA01416.1 - 1.3e-27 96.3 1.5 1.7e-27 96.0 0.4 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KKA01416.1 - 2.3e-26 91.6 0.2 5.2e-26 90.5 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KKA01416.1 - 8.2e-13 48.2 2.7 1.6e-12 47.3 2.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKA01416.1 - 5.9e-12 45.3 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF1496 PF07383.12 KKA01416.1 - 0.097 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) HDA2-3 PF11496.8 KKA01417.1 - 3.3e-10 39.6 22.1 3.3e-10 39.6 22.1 4.4 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 MtrG PF04210.13 KKA01417.1 - 8.8 6.3 7.5 6.8 6.6 0.6 3.4 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Prenyltrans PF00432.21 KKA01418.1 - 3.1e-40 135.6 2.5 2.1e-11 43.3 1.5 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat AAA PF00004.29 KKA01420.1 - 1.3e-43 148.6 0.0 2.4e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KKA01420.1 - 7.2e-28 96.4 0.4 4.1e-27 93.9 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KKA01420.1 - 2.7e-22 78.6 5.5 8e-22 77.1 5.5 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KKA01420.1 - 1.2e-06 28.2 0.0 1.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KKA01420.1 - 1.5e-06 28.0 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKA01420.1 - 1.8e-06 28.5 0.2 0.0013 19.2 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKA01420.1 - 1.5e-05 25.3 0.3 0.0028 17.9 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKA01420.1 - 4.6e-05 23.4 0.0 0.00016 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KKA01420.1 - 5.3e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KKA01420.1 - 5.9e-05 22.4 0.0 9.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KKA01420.1 - 7.9e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KKA01420.1 - 8.2e-05 22.6 0.6 0.00024 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KKA01420.1 - 0.00011 22.3 0.7 0.00073 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KKA01420.1 - 0.0011 19.6 0.2 0.003 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KKA01420.1 - 0.0012 19.1 0.0 0.0061 16.9 0.0 2.3 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 KKA01420.1 - 0.0023 18.1 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKA01420.1 - 0.0023 17.7 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KKA01420.1 - 0.0066 16.0 0.4 0.21 11.2 0.1 2.3 1 1 0 2 2 2 1 AAA domain TniB PF05621.11 KKA01420.1 - 0.011 15.2 0.1 2.6 7.4 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 KKA01420.1 - 0.018 15.5 0.2 0.069 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKA01420.1 - 0.02 14.4 0.0 0.051 13.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 KKA01420.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase PF06745.13 KKA01420.1 - 0.024 14.0 4.5 0.83 8.9 0.1 2.8 2 1 1 3 3 3 0 KaiC NACHT PF05729.12 KKA01420.1 - 0.028 14.3 0.0 0.58 10.1 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KKA01420.1 - 0.047 13.1 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KKA01420.1 - 0.06 12.8 0.9 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 KKA01420.1 - 0.068 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KKA01420.1 - 0.079 12.7 0.0 0.3 10.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KKA01420.1 - 0.12 12.1 0.0 0.87 9.3 0.0 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 KKA01420.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 KKA01420.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KKA01420.1 - 0.16 12.5 0.6 0.62 10.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Tae4 PF14113.6 KKA01420.1 - 0.34 11.1 1.9 0.84 9.9 1.6 1.8 1 1 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 PAPS_reduct PF01507.19 KKA01421.1 - 5.6e-32 111.2 0.0 7.2e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ArgoMid PF16487.5 KKA01421.1 - 0.034 14.4 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute EHD_N PF16880.5 KKA01421.1 - 0.33 10.9 0.2 0.33 10.9 0.2 2.3 2 0 0 2 2 2 0 N-terminal EH-domain containing protein Ribosomal_S14 PF00253.21 KKA01422.1 - 5.2e-12 45.3 0.1 9.8e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e RRM_1 PF00076.22 KKA01423.1 - 6.9e-08 32.2 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5434 PF17502.2 KKA01423.1 - 0.52 10.3 11.9 6 6.8 0.7 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5434) Pkinase PF00069.25 KKA01424.1 - 9.1e-62 208.8 0.0 4.6e-61 206.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01424.1 - 8e-25 87.6 0.1 7.2e-23 81.2 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA01424.1 - 9.3e-05 21.5 1.8 9.3e-05 21.5 1.8 2.4 2 2 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KKA01424.1 - 0.021 13.9 0.1 0.045 12.8 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 RGS PF00615.19 KKA01425.1 - 2.8e-14 53.4 6.9 3e-09 37.2 0.8 3.7 3 0 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.21 KKA01425.1 - 1.8e-09 37.5 0.1 5.4e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YolD PF08863.10 KKA01425.1 - 0.017 15.1 0.3 0.16 12.0 0.0 2.7 2 0 0 2 2 2 0 YolD-like protein MFS_1 PF07690.16 KKA01426.1 - 3.3e-22 78.9 14.4 3.8e-14 52.4 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKA01426.1 - 1.2e-10 40.8 17.1 4.6e-07 29.0 5.4 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KKA01426.1 - 2.9e-06 26.1 19.6 1.6e-05 23.6 6.2 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein AAA PF00004.29 KKA01428.1 - 8.3e-43 146.0 0.0 1.5e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA01428.1 - 9.6e-15 54.1 0.2 2.4e-14 52.9 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KKA01428.1 - 1.2e-07 31.6 0.2 2.7e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KKA01428.1 - 2.9e-07 30.8 0.1 8.4e-07 29.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKA01428.1 - 4e-06 26.9 0.0 3.5e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKA01428.1 - 9e-06 26.0 0.1 0.004 17.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKA01428.1 - 9.9e-06 26.0 0.0 0.00015 22.2 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KKA01428.1 - 0.00017 21.4 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KKA01428.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KKA01428.1 - 0.0021 18.2 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CCDC154 PF15450.6 KKA01428.1 - 0.0039 15.8 1.3 0.0063 15.1 1.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 AAA_18 PF13238.6 KKA01428.1 - 0.0039 17.7 0.0 0.022 15.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain DUF2072 PF09845.9 KKA01428.1 - 0.0049 17.1 1.4 0.01 16.1 1.4 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein AAA_28 PF13521.6 KKA01428.1 - 0.0055 17.0 0.0 0.0095 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KKA01428.1 - 0.012 15.1 0.0 0.061 12.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 KKA01428.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KKA01428.1 - 0.014 14.6 0.0 0.038 13.2 0.0 1.8 1 1 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KKA01428.1 - 0.015 14.7 0.1 0.04 13.3 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKA01428.1 - 0.017 15.5 0.0 0.051 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DivIC PF04977.15 KKA01428.1 - 0.017 14.8 0.8 0.055 13.3 0.8 1.8 1 0 0 1 1 1 0 Septum formation initiator EzrA PF06160.12 KKA01428.1 - 0.022 13.0 2.4 0.084 11.0 0.4 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TsaE PF02367.17 KKA01428.1 - 0.022 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KKA01428.1 - 0.025 14.6 0.0 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 KKA01428.1 - 0.026 15.1 0.5 0.08 13.6 0.5 1.8 1 0 0 1 1 1 0 SlyX AAA_24 PF13479.6 KKA01428.1 - 0.029 14.1 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KKA01428.1 - 0.034 13.8 0.0 0.18 11.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Spc7 PF08317.11 KKA01428.1 - 0.036 13.0 0.7 0.092 11.6 0.7 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_25 PF13481.6 KKA01428.1 - 0.036 13.6 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.12 KKA01428.1 - 0.038 14.0 2.0 1.9 8.5 0.6 2.8 3 0 0 3 3 2 0 Laminin Domain II AAA_7 PF12775.7 KKA01428.1 - 0.048 13.2 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4763 PF15960.5 KKA01428.1 - 0.054 12.8 2.9 0.1 11.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Serine_rich PF08824.10 KKA01428.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain ATPase PF06745.13 KKA01428.1 - 0.068 12.5 0.3 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 KKA01428.1 - 0.068 12.4 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 KKA01428.1 - 0.07 12.9 0.7 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KKA01428.1 - 0.072 12.2 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4988 PF16378.5 KKA01428.1 - 0.073 12.7 0.5 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function ABC_tran PF00005.27 KKA01428.1 - 0.12 12.9 0.0 0.45 11.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KKA01428.1 - 0.12 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KKA01428.1 - 0.13 12.6 0.1 0.92 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain Sipho_Gp157 PF05565.11 KKA01428.1 - 0.18 11.8 3.1 0.19 11.8 0.6 2.2 2 0 0 2 2 2 0 Siphovirus Gp157 BRX_N PF13713.6 KKA01428.1 - 0.31 10.8 1.1 10 6.0 0.0 3.2 4 0 0 4 4 3 0 Transcription factor BRX N-terminal domain FlaC_arch PF05377.11 KKA01428.1 - 3.1 8.3 7.1 4.8 7.7 4.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MIF4G PF02854.19 KKA01429.1 - 1.4e-06 28.1 7.9 1.1e-05 25.2 6.5 2.5 1 1 0 1 1 1 1 MIF4G domain ABC_tran PF00005.27 KKA01430.1 - 1.5e-50 171.3 0.4 7.3e-28 97.8 0.1 3.0 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKA01430.1 - 2.8e-39 135.4 50.7 1.2e-31 110.4 23.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_15 PF13175.6 KKA01430.1 - 6.3e-09 36.0 0.0 2.9e-05 23.9 0.0 3.8 2 2 2 4 4 4 1 AAA ATPase domain SMC_N PF02463.19 KKA01430.1 - 2.2e-08 33.8 12.3 0.0029 17.1 0.2 4.6 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKA01430.1 - 4.5e-07 29.5 1.1 4e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KKA01430.1 - 1.5e-06 28.7 0.0 0.029 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKA01430.1 - 2.7e-05 24.1 1.5 0.0095 15.9 0.2 2.7 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KKA01430.1 - 0.0002 20.6 0.1 0.0082 15.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 KKA01430.1 - 0.00046 20.1 3.5 0.48 10.2 0.2 4.3 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KKA01430.1 - 0.00061 19.6 0.3 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKA01430.1 - 0.00076 18.7 0.4 0.18 10.9 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KKA01430.1 - 0.00081 19.5 0.8 1.4 9.0 0.2 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KKA01430.1 - 0.00094 18.9 0.3 0.28 10.9 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 KKA01430.1 - 0.0016 19.0 4.4 0.054 14.0 0.0 3.7 4 0 0 4 4 2 1 AAA domain AAA_22 PF13401.6 KKA01430.1 - 0.0025 18.1 1.8 1.7 8.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKA01430.1 - 0.0044 17.5 6.9 0.0044 17.5 6.9 4.1 4 1 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 KKA01430.1 - 0.0064 15.8 0.0 0.54 9.5 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 KKA01430.1 - 0.011 15.2 1.2 1.9 8.0 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA PF00004.29 KKA01430.1 - 0.02 15.3 0.5 2.9 8.3 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KKA01430.1 - 0.027 14.8 2.8 5.6 7.4 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ATPase_2 PF01637.18 KKA01430.1 - 0.03 14.3 3.8 0.61 10.0 0.0 4.1 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KKA01430.1 - 0.034 13.5 0.2 4.3 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 KKA01430.1 - 0.04 13.8 0.2 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 KKA01430.1 - 0.057 13.5 1.9 0.091 12.8 0.1 2.3 2 0 0 2 2 1 0 Helicase HerA, central domain NACHT PF05729.12 KKA01430.1 - 0.073 13.0 0.7 1 9.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 KKA01430.1 - 0.076 12.3 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA12 PF10443.9 KKA01430.1 - 0.078 11.7 0.0 0.078 11.7 0.0 2.3 2 1 1 3 3 3 0 RNA12 protein AAA_5 PF07728.14 KKA01430.1 - 0.1 12.6 0.4 7.3 6.6 0.1 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KKA01430.1 - 0.11 12.0 0.5 0.89 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KKA01430.1 - 0.13 11.9 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 KKA01430.1 - 0.14 11.8 4.5 0.36 10.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 KKA01430.1 - 0.27 10.8 1.4 0.45 10.1 0.1 2.1 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KKA01430.1 - 0.55 10.1 3.0 1.3 8.9 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_14 PF13173.6 KKA01430.1 - 0.6 10.2 2.9 2.9 7.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KKA01430.1 - 0.93 9.2 4.1 2.2 8.0 0.0 3.5 5 0 0 5 5 4 0 AAA domain AAA_28 PF13521.6 KKA01430.1 - 1.4 9.1 3.3 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKA01431.1 - 1.2e-50 171.6 0.3 5.9e-28 98.1 0.1 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKA01431.1 - 2.3e-40 139.0 43.6 4.5e-32 111.8 23.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKA01431.1 - 1.1e-08 34.8 12.1 0.0035 16.8 0.1 4.6 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KKA01431.1 - 1.4e-08 34.8 0.0 6.2e-05 22.9 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KKA01431.1 - 3.8e-07 29.8 1.1 4.1e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KKA01431.1 - 7.1e-07 29.8 0.0 0.017 15.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKA01431.1 - 4.2e-05 23.5 1.4 0.018 14.9 0.2 2.7 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KKA01431.1 - 0.00011 21.3 0.1 0.0057 15.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 KKA01431.1 - 0.00027 20.8 3.8 0.41 10.4 0.2 4.4 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KKA01431.1 - 0.00052 20.1 0.8 1.2 9.3 0.2 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF815 PF05673.13 KKA01431.1 - 0.00053 19.2 0.5 0.15 11.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KKA01431.1 - 0.00097 18.9 0.3 0.39 10.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.6 KKA01431.1 - 0.0013 18.5 2.2 0.26 11.0 0.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKA01431.1 - 0.0015 18.8 1.7 1.5 9.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKA01431.1 - 0.0016 19.0 5.2 0.045 14.3 0.0 3.8 4 0 0 4 4 2 1 AAA domain AAA_23 PF13476.6 KKA01431.1 - 0.0023 18.4 6.1 0.0023 18.4 6.1 4.2 4 1 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 KKA01431.1 - 0.0033 16.7 0.0 0.36 10.1 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 KKA01431.1 - 0.0074 15.8 1.1 1.6 8.2 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KKA01431.1 - 0.011 16.2 2.1 4.7 7.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA PF00004.29 KKA01431.1 - 0.014 15.8 0.6 2.4 8.6 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKA01431.1 - 0.023 14.6 0.2 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 KKA01431.1 - 0.039 14.1 1.9 0.077 13.1 0.1 2.5 2 0 0 2 2 1 0 Helicase HerA, central domain NACHT PF05729.12 KKA01431.1 - 0.057 13.3 0.7 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 KKA01431.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA12 PF10443.9 KKA01431.1 - 0.06 12.1 0.0 0.06 12.1 0.0 2.3 2 1 1 3 3 3 0 RNA12 protein AAA_5 PF07728.14 KKA01431.1 - 0.071 13.1 0.4 6.2 6.8 0.1 3.2 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KKA01431.1 - 0.093 12.3 0.4 0.85 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKA01431.1 - 0.097 12.4 4.7 0.3 10.8 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_27 PF13514.6 KKA01431.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKA01431.1 - 0.11 11.8 2.1 4.6 6.5 0.0 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.6 KKA01431.1 - 0.14 12.4 0.0 28 5.0 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KKA01431.1 - 0.15 11.7 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 KKA01431.1 - 0.19 11.3 1.1 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 KKA01431.1 - 0.31 10.8 4.1 1.7 8.4 0.0 3.8 5 0 0 5 5 5 0 AAA domain AAA_14 PF13173.6 KKA01431.1 - 0.47 10.5 3.1 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KKA01431.1 - 0.49 10.3 3.2 1.1 9.1 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.6 KKA01431.1 - 0.99 9.6 3.3 3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KKA01431.1 - 1.6 8.5 8.2 0.52 10.2 0.1 3.4 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Exo_endo_phos PF03372.23 KKA01432.1 - 3.9e-11 42.9 0.0 7.8e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KKA01432.1 - 3.5e-08 33.4 5.9 3.1e-06 27.2 0.6 2.7 2 0 0 2 2 2 2 GRF zinc finger Exo_endo_phos_2 PF14529.6 KKA01432.1 - 0.00032 20.5 0.0 0.52 10.2 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Ly49 PF08391.10 KKA01432.1 - 2.9 8.2 5.7 1.7 9.0 2.0 2.6 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Pkinase PF00069.25 KKA01433.1 - 1.2e-65 221.5 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01433.1 - 2.4e-28 99.2 0.0 3.2e-28 98.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA01433.1 - 0.0029 16.6 0.7 0.014 14.3 0.7 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKA01433.1 - 0.028 14.3 0.4 0.06 13.3 0.4 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KKA01433.1 - 0.042 13.4 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family AcetylCoA_hyd_C PF13336.6 KKA01434.1 - 2.8e-37 128.0 0.0 4.7e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KKA01434.1 - 2.4e-33 115.8 0.0 4.3e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.23 KKA01434.1 - 0.015 14.7 0.0 0.12 11.7 0.0 2.4 3 0 0 3 3 3 0 Coenzyme A transferase Acid_PPase PF12689.7 KKA01435.1 - 2.6e-39 134.8 0.0 3.3e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 KKA01435.1 - 0.0059 16.7 0.1 0.037 14.1 0.0 1.9 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KKA01436.1 - 1.2e-31 110.0 34.8 1.2e-31 110.0 34.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA01436.1 - 4.1e-05 22.6 13.2 4.1e-05 22.6 13.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KKA01436.1 - 0.0031 16.0 4.7 0.0061 15.0 4.7 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector zf-CCHC PF00098.23 KKA01437.1 - 5.7e-06 26.2 1.7 8.6e-06 25.6 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KKA01437.1 - 0.00018 21.2 2.5 0.00027 20.7 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KKA01437.1 - 0.37 10.6 2.0 0.7 9.7 2.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger E1-E2_ATPase PF00122.20 KKA01438.1 - 4.7e-34 117.5 0.4 1.5e-33 115.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KKA01438.1 - 7.6e-33 114.6 0.1 1.2e-32 114.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKA01438.1 - 1.5e-13 51.0 3.2 0.00061 20.2 0.2 4.2 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.7 KKA01438.1 - 0.00043 20.7 0.0 0.00077 19.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2680 PF10925.8 KKA01438.1 - 0.034 14.2 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) CBFD_NFYB_HMF PF00808.23 KKA01439.1 - 4.5e-18 65.3 0.9 1.2e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKA01439.1 - 0.11 12.9 0.0 0.11 12.9 0.0 2.1 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Lon_C PF05362.13 KKA01440.1 - 5.9e-61 205.6 0.0 1.2e-60 204.5 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKA01440.1 - 2.2e-30 106.1 1.3 2.2e-30 106.1 1.3 2.6 4 0 0 4 4 3 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKA01440.1 - 3.1e-24 85.9 1.6 1e-21 77.7 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KKA01440.1 - 8.9e-07 28.8 0.4 2.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 KKA01440.1 - 1.3e-05 24.3 0.0 3.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KKA01440.1 - 4.9e-05 23.1 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKA01440.1 - 5.6e-05 23.6 0.1 0.0003 21.2 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KKA01440.1 - 7.1e-05 22.8 0.0 0.00025 21.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKA01440.1 - 0.0003 21.1 0.8 0.01 16.1 0.1 3.4 3 1 0 3 3 1 1 AAA domain AAA_18 PF13238.6 KKA01440.1 - 0.0011 19.5 0.6 0.013 16.1 0.0 3.1 3 1 1 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 KKA01440.1 - 0.0083 16.0 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 KKA01440.1 - 0.022 15.1 0.4 0.16 12.4 0.0 2.7 3 0 0 3 3 2 0 RNA helicase AAA_3 PF07726.11 KKA01440.1 - 0.025 14.4 0.0 0.088 12.7 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 KKA01440.1 - 0.027 14.6 0.2 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.17 KKA01440.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KKA01440.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKA01440.1 - 0.091 13.3 0.1 0.091 13.3 0.1 3.8 4 1 0 4 4 4 0 ABC transporter AAA_19 PF13245.6 KKA01440.1 - 0.34 11.2 2.6 0.52 10.6 0.1 2.6 4 0 0 4 4 3 0 AAA domain MIEAP PF16026.5 KKA01440.1 - 0.47 10.6 6.8 0.21 11.8 0.7 2.7 2 0 0 2 2 2 0 Mitochondria-eating protein MCM PF00493.23 KKA01441.1 - 7.5e-102 339.2 1.3 1.2e-101 338.5 1.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKA01441.1 - 2.4e-38 130.8 0.2 4.6e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKA01441.1 - 8.7e-24 83.8 0.5 2.4e-23 82.4 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 KKA01441.1 - 3.1e-10 40.6 35.0 3.1e-10 40.6 35.0 4.3 4 1 1 5 5 4 2 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KKA01441.1 - 4.4e-10 40.1 0.3 1.8e-09 38.1 0.3 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKA01441.1 - 1.3e-09 37.7 0.1 2.2e-07 30.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKA01441.1 - 8.7e-07 29.0 0.0 2.8e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKA01441.1 - 0.0011 18.8 0.0 0.0035 17.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKA01441.1 - 0.0022 17.7 0.5 0.018 14.8 0.1 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain SelR PF01641.18 KKA01441.1 - 0.0093 16.0 0.2 0.41 10.7 0.1 2.4 2 0 0 2 2 2 1 SelR domain AAA_30 PF13604.6 KKA01441.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain GIT_SHD PF08518.11 KKA01442.1 - 2.9e-17 62.0 14.5 2.2e-09 36.7 0.3 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KKA01442.1 - 0.0024 17.9 0.9 0.0024 17.9 0.9 2.7 2 1 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF4279 PF14106.6 KKA01442.1 - 0.24 11.6 2.7 0.94 9.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DEAD PF00270.29 KKA01444.1 - 6e-29 101.1 0.5 1.1e-28 100.1 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA01444.1 - 1.5e-25 89.7 2.2 5.6e-25 87.8 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KKA01444.1 - 0.0031 17.9 0.0 0.0077 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM_lid PF17855.1 KKA01445.1 - 3.2e-10 40.3 0.6 6.3e-10 39.3 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 KKA01446.1 - 2.7e-101 337.4 0.0 4e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKA01446.1 - 1.9e-37 127.9 0.5 3.8e-37 126.9 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KKA01446.1 - 7e-13 49.1 2.1 2.4e-12 47.3 2.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KKA01446.1 - 1.2e-08 35.3 0.0 3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KKA01446.1 - 4.4e-06 26.2 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKA01446.1 - 5.1e-06 26.5 0.0 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKA01446.1 - 0.00058 19.7 0.0 0.0052 16.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mss4 PF04421.13 KKA01449.1 - 1.7e-15 56.9 0.1 2.2e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Mss4 protein Ribosomal_S3Ae PF01015.18 KKA01449.1 - 0.026 14.1 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family eIF-6 PF01912.18 KKA01450.1 - 2.8e-80 268.3 1.2 3.6e-80 268.0 1.2 1.1 1 0 0 1 1 1 1 eIF-6 family Flocculin PF00624.18 KKA01451.1 - 7.2e-13 48.6 43.4 3.6e-08 33.5 11.8 19.4 14 6 6 20 20 20 5 Flocculin repeat NIF PF03031.18 KKA01452.1 - 3.1e-22 79.0 0.6 8.8e-22 77.5 0.6 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KKA01452.1 - 0.083 13.3 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.6 KKA01452.1 - 0.13 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like CTU2 PF10288.9 KKA01452.1 - 0.37 11.1 2.6 0.23 11.7 0.3 1.9 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Cwf_Cwc_15 PF04889.12 KKA01452.1 - 0.91 9.2 16.2 0.44 10.2 6.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PGM_PMM_I PF02878.16 KKA01453.1 - 9.1e-39 132.3 0.1 1.7e-38 131.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KKA01453.1 - 1.7e-22 80.0 0.1 1.9e-21 76.6 0.1 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKA01453.1 - 3.5e-18 65.9 0.0 8.9e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KKA01453.1 - 9.4e-05 22.5 0.1 0.00034 20.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Anp1 PF03452.14 KKA01454.1 - 2.8e-114 381.0 0.0 4.6e-114 380.3 0.0 1.3 1 0 0 1 1 1 1 Anp1 TssN PF17555.2 KKA01454.1 - 0.032 13.6 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN PIG-L PF02585.17 KKA01456.1 - 2.1e-14 54.3 0.2 9e-14 52.2 0.2 1.9 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF5394 PF17372.2 KKA01456.1 - 0.27 10.8 3.6 0.41 10.2 3.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5394) Pkinase PF00069.25 KKA01458.1 - 2.1e-29 102.7 3.8 4.5e-29 101.6 0.2 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01458.1 - 8.5e-12 44.9 0.0 4.1e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA01458.1 - 0.0015 17.6 0.5 0.0015 17.6 0.5 3.1 3 1 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 KKA01458.1 - 0.0063 16.5 0.2 0.01 15.7 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKA01458.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KKA01458.1 - 0.024 13.4 0.0 0.024 13.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF4698 PF15769.5 KKA01458.1 - 0.22 10.5 0.1 0.22 10.5 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4698) zf-RING_2 PF13639.6 KKA01459.1 - 1.6e-07 31.5 7.8 3.7e-07 30.4 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KKA01459.1 - 5.3e-06 26.4 2.5 1.4e-05 25.1 2.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KKA01459.1 - 3e-05 24.1 8.3 3.2e-05 24.0 5.8 2.5 3 0 0 3 3 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KKA01459.1 - 0.0002 21.6 8.0 0.00051 20.3 8.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KKA01459.1 - 0.0033 17.5 6.1 0.0074 16.4 6.1 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 KKA01459.1 - 0.032 14.1 10.4 0.077 12.9 10.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKA01459.1 - 0.051 13.4 7.8 0.12 12.3 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKA01459.1 - 0.068 12.8 4.3 0.15 11.7 4.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KKA01459.1 - 0.083 13.2 7.7 0.17 12.2 7.7 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KKA01459.1 - 0.83 9.5 9.0 51 3.8 8.9 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RUN PF02759.19 KKA01459.1 - 1.4 8.9 4.3 3 7.8 0.1 3.5 4 0 0 4 4 4 0 RUN domain zf-C3HC4_3 PF13920.6 KKA01459.1 - 1.5 8.7 7.0 69 3.4 7.0 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KKA01459.1 - 1.9 8.4 5.7 5 7.1 5.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 KKA01459.1 - 3.7 7.5 9.2 0.6 10.0 1.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 HCBP_related PF06594.11 KKA01459.1 - 8.8 6.4 6.6 3 7.8 1.6 2.7 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Abhydrolase_1 PF00561.20 KKA01460.1 - 4.4e-12 46.2 0.1 7.8e-12 45.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA01460.1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKA01460.1 - 1.6e-08 35.4 0.0 2.4e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KKA01460.1 - 9.4e-06 25.4 0.7 2.2e-05 24.2 0.0 2.0 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 KKA01460.1 - 0.00083 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 KKA01460.1 - 0.0022 17.9 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 KKA01460.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PP2C PF00481.21 KKA01461.1 - 9.9e-72 241.7 0.7 1.2e-71 241.4 0.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C RED_N PF07808.13 KKA01461.1 - 0.047 13.3 0.2 0.072 12.7 0.2 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF1853 PF08907.11 KKA01461.1 - 0.079 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) tRNA_Me_trans PF03054.16 KKA01462.1 - 6.8e-75 252.1 7.4 5.2e-58 196.5 1.5 2.1 1 1 1 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 KKA01462.1 - 5.2e-06 25.8 0.0 3.4e-05 23.1 0.0 2.3 3 0 0 3 3 3 1 NAD synthase Recep_L_domain PF01030.24 KKA01463.1 - 3.1e-07 30.5 12.1 0.015 15.4 0.7 4.8 1 1 2 4 4 4 4 Receptor L domain DUF1859 PF08948.10 KKA01463.1 - 0.017 15.1 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) LRR_4 PF12799.7 KKA01463.1 - 0.29 11.6 26.2 1.8 9.1 2.1 5.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF711 PF05167.12 KKA01464.1 - 0.1 11.4 1.3 0.16 10.8 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) NAD_Gly3P_dh_C PF07479.14 KKA01465.1 - 8.1e-38 129.9 0.1 1.2e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KKA01465.1 - 1.4e-36 125.8 0.0 7.1e-36 123.5 0.0 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AMP-binding PF00501.28 KKA01466.1 - 3e-82 276.5 0.0 4.1e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme COX6B PF02297.17 KKA01467.1 - 2.2e-23 82.3 6.9 2.9e-23 81.9 6.9 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RPN6_C_helix PF18503.1 KKA01468.1 - 0.0041 16.8 0.5 1.4 8.7 0.0 2.9 2 0 0 2 2 2 2 26S proteasome subunit RPN6 C-terminal helix domain COG5 PF10392.9 KKA01468.1 - 0.013 15.7 0.8 4.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Perilipin PF03036.16 KKA01468.1 - 0.02 14.0 0.3 0.042 12.9 0.1 1.6 1 1 0 1 1 1 0 Perilipin family adh_short PF00106.25 KKA01470.1 - 2.1e-39 135.0 0.0 2.9e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKA01470.1 - 1.2e-26 93.7 0.0 1.5e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKA01470.1 - 3.2e-05 23.9 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKA01470.1 - 0.043 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KKA01470.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Transket_pyr PF02779.24 KKA01471.1 - 1.8e-62 210.2 0.0 3.1e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KKA01471.1 - 3.7e-57 193.6 0.0 5.5e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KKA01471.1 - 9.3e-51 171.5 0.0 1.6e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KKA01471.1 - 1.2e-18 66.4 1.5 1.2e-18 66.4 1.5 1.7 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Ribosomal_L6 PF00347.23 KKA01472.1 - 2e-26 92.4 10.3 2.6e-14 53.6 2.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.12 KKA01472.1 - 0.076 13.4 7.0 0.49 10.8 0.4 3.0 1 1 1 3 3 3 0 YbbR-like protein SNF2_N PF00176.23 KKA01473.1 - 3.9e-75 252.8 0.4 8.9e-75 251.6 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA01473.1 - 2.9e-22 79.1 0.0 1.6e-19 70.3 0.0 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KKA01473.1 - 4.7e-11 42.6 0.9 3.6e-10 39.8 0.1 3.0 3 0 0 3 3 3 1 Bromodomain ResIII PF04851.15 KKA01473.1 - 5.5e-11 42.8 0.0 5.5e-11 42.8 0.0 3.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit SnAC PF14619.6 KKA01473.1 - 2.5e-06 28.0 2.5 2.5e-06 28.0 2.5 4.6 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 KKA01473.1 - 0.0014 18.9 3.1 0.0014 18.9 3.1 2.9 2 0 0 2 2 2 1 HSA DUF4827 PF16109.5 KKA01473.1 - 0.026 14.5 2.5 0.089 12.8 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) FlpD PF02662.16 KKA01473.1 - 0.99 9.4 2.7 41 4.2 0.3 3.3 3 0 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit RRT14 PF17075.5 KKA01474.1 - 2.8e-29 102.6 34.6 1.7e-28 100.1 34.6 1.8 1 1 0 1 1 1 1 Regular of rDNA transcription protein 14 FBPase PF00316.20 KKA01474.1 - 0.15 11.5 1.1 0.27 10.7 1.1 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain DUF4962 PF16332.5 KKA01474.1 - 3.9 5.9 15.3 7.8 4.9 15.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4962) MMS19_N PF14500.6 KKA01475.1 - 1.7e-69 234.3 12.2 2.2e-67 227.4 2.6 3.8 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KKA01475.1 - 1.5e-40 139.7 25.2 1.5e-40 139.7 25.2 3.6 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 KKA01475.1 - 0.0056 17.2 0.1 0.78 10.3 0.0 4.1 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KKA01475.1 - 0.17 12.3 0.1 7.8 7.0 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats RTP1_C1 PF10363.9 KKA01475.1 - 0.51 10.5 5.9 0.56 10.4 0.3 3.9 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KKA01475.1 - 1.2 9.6 4.4 71 4.1 0.3 4.4 4 0 0 4 4 4 0 HEAT repeat Myf5 PF12232.8 KKA01475.1 - 3.3 8.6 4.5 20 6.0 0.1 3.5 3 0 0 3 3 3 0 Myogenic determination factor 5 MOR2-PAG1_N PF14222.6 KKA01476.1 - 1.7e-139 466.3 16.1 3.6e-139 465.2 16.1 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KKA01476.1 - 9.9e-76 254.9 0.2 7.3e-75 252.1 0.2 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KKA01476.1 - 2.1e-12 45.6 18.7 1.3e-10 39.7 1.4 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region Fungal_trans PF04082.18 KKA01477.1 - 2.5e-27 95.6 0.4 7e-27 94.1 0.4 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA01477.1 - 1.6e-05 24.9 7.4 4.4e-05 23.5 7.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KKA01479.1 - 1e-61 204.8 5.8 2.4e-20 72.3 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX14 PF14880.6 KKA01479.1 - 0.081 12.8 0.2 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly 2-oxoacid_dh PF00198.23 KKA01480.1 - 2.8e-75 252.7 1.9 3.7e-75 252.4 1.9 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKA01480.1 - 1.5e-14 53.6 0.1 3.3e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKA01480.1 - 7.8e-14 51.7 0.1 7.8e-14 51.7 0.1 2.4 3 0 0 3 3 3 1 e3 binding domain RNase_HII PF01351.18 KKA01481.1 - 3e-57 193.7 0.0 3.9e-56 190.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease HII tRNA-synt_2 PF00152.20 KKA01482.1 - 1.2e-61 208.6 0.2 2.1e-61 207.7 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KKA01482.1 - 0.00027 20.5 0.5 0.014 14.9 0.1 2.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 KKA01482.1 - 0.012 15.8 0.0 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 KKA01482.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4143 PF13635.6 KKA01482.1 - 0.026 14.7 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) DUF1959 PF09218.10 KKA01482.1 - 0.047 13.8 1.0 0.32 11.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) Brix PF04427.18 KKA01484.1 - 5e-31 108.3 0.6 6.6e-31 107.9 0.6 1.2 1 0 0 1 1 1 1 Brix domain SirA PF10747.9 KKA01484.1 - 0.13 12.6 0.5 0.21 11.9 0.5 1.4 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA GH43_C PF16369.5 KKA01485.1 - 1.1 9.9 6.1 2.2 9.0 2.0 2.6 2 0 0 2 2 2 0 C-terminal lipocalin-like domain ApoLp-III PF07464.11 KKA01486.1 - 9e-05 22.6 19.6 0.0025 17.9 6.6 2.8 2 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 KKA01486.1 - 0.00024 21.0 6.2 0.16 11.8 0.1 3.3 2 2 0 3 3 3 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KKA01486.1 - 0.00055 20.5 12.4 0.44 11.2 0.1 5.4 2 2 4 6 6 6 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KKA01486.1 - 0.0024 18.4 32.6 0.028 14.9 2.6 5.7 2 2 2 4 4 4 2 YtxH-like protein Prefoldin_3 PF13758.6 KKA01486.1 - 0.0086 16.1 4.5 0.61 10.2 0.1 3.9 4 0 0 4 4 4 1 Prefoldin subunit ATP-synt_B PF00430.18 KKA01486.1 - 0.13 12.4 2.7 0.27 11.3 0.0 2.8 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) betaPIX_CC PF16523.5 KKA01486.1 - 0.14 12.0 3.0 0.18 11.6 0.2 2.6 2 0 0 2 2 2 0 betaPIX coiled coil HIP1_clath_bdg PF16515.5 KKA01486.1 - 0.77 10.4 0.1 0.77 10.4 0.1 4.0 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 KKA01486.1 - 1.1 7.2 9.9 2.2 6.1 2.3 2.4 2 0 0 2 2 2 0 Prominin Syntaxin-6_N PF09177.11 KKA01486.1 - 1.3 9.6 18.8 11 6.6 8.5 4.0 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KKA01486.1 - 1.3 9.0 7.2 9.6 6.2 0.2 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 KKA01486.1 - 3 7.9 19.7 10 6.2 8.0 3.1 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KKA01486.1 - 3.4 7.5 5.9 1.2 9.0 0.4 3.0 2 1 1 3 3 3 0 Septum formation initiator FAM184 PF15665.5 KKA01486.1 - 3.6 7.3 12.6 0.34 10.7 0.5 3.0 2 2 1 3 3 3 0 Family with sequence similarity 184, A and B Spectrin PF00435.21 KKA01486.1 - 3.7 8.1 11.7 20 5.7 0.3 3.7 3 0 0 3 3 3 0 Spectrin repeat TPR_MLP1_2 PF07926.12 KKA01486.1 - 4.5 7.3 15.6 0.58 10.2 1.3 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 KKA01486.1 - 6.9 7.1 7.6 13 6.3 0.1 4.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Phasin PF05597.11 KKA01486.1 - 8.6 6.4 20.8 27 4.8 2.4 4.8 2 2 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Muted PF14942.6 KKA01486.1 - 9.8 6.5 17.2 0.34 11.2 2.3 3.2 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3268 PF11672.8 KKA01487.1 - 0.019 15.3 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 zinc-finger-containing domain EOS1 PF12326.8 KKA01488.1 - 2.6e-38 131.7 14.6 2.6e-38 131.7 14.6 3.2 2 1 0 2 2 2 1 N-glycosylation protein DUF2457 PF10446.9 KKA01488.1 - 0.27 10.3 8.3 0.073 12.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) ETRAMP PF09716.10 KKA01488.1 - 0.72 10.0 0.0 0.72 10.0 0.0 3.1 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ribosomal_S13 PF00416.22 KKA01489.1 - 1.9e-19 70.3 0.4 3.6e-17 63.0 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KKA01489.1 - 6.9e-06 25.1 0.0 6.9e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_5 PF14520.6 KKA01489.1 - 0.0096 16.5 0.1 0.017 15.7 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KKA01489.1 - 0.031 14.1 0.0 0.085 12.7 0.0 1.8 1 1 0 1 1 1 0 Fingers domain of DNA polymerase lambda IMS_HHH PF11798.8 KKA01489.1 - 0.22 11.9 0.6 0.75 10.3 0.0 2.2 3 0 0 3 3 3 0 IMS family HHH motif MutL_C PF08676.11 KKA01490.1 - 1.5e-23 83.2 0.1 6.5e-23 81.1 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KKA01490.1 - 7.5e-19 67.6 0.6 3.7e-18 65.3 0.2 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKA01490.1 - 5.5e-12 45.7 0.8 2.5e-11 43.5 0.8 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKA01490.1 - 1.6e-05 25.4 0.5 6.9e-05 23.3 0.5 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 KKA01492.1 - 8.6e-67 221.1 0.6 2.5e-24 85.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 KKA01492.1 - 0.00079 19.2 4.1 0.06 13.3 1.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KKA01492.1 - 0.021 14.4 4.0 0.17 11.5 0.5 3.3 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 KKA01492.1 - 0.029 14.8 4.2 0.056 13.9 1.7 2.7 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KKA01492.1 - 0.33 10.5 3.4 2.1 8.0 1.5 2.6 2 0 0 2 2 2 0 EF hand zf-CRD PF17979.1 KKA01492.1 - 9.8 6.3 7.4 7.6 6.6 3.6 2.4 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Cpn60_TCP1 PF00118.24 KKA01494.1 - 2.2e-150 501.6 13.0 2.5e-150 501.4 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 KKA01494.1 - 0.048 13.6 0.2 1 9.2 0.1 2.5 2 0 0 2 2 2 0 DAK2 domain CRM1_repeat PF18777.1 KKA01494.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat EF-hand_4 PF12763.7 KKA01495.1 - 1.7e-43 146.8 7.0 1e-40 137.9 1.8 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 KKA01495.1 - 1.5e-33 116.7 10.1 1.5e-33 116.7 10.1 2.2 2 1 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 KKA01495.1 - 0.0003 20.1 0.8 0.0009 18.6 0.8 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KKA01495.1 - 0.014 15.9 0.1 0.048 14.1 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KKA01495.1 - 0.031 14.2 0.8 0.12 12.3 0.8 2.0 1 0 0 1 1 1 0 EF-hand domain BPL_LplA_LipB_2 PF16917.5 KKA01495.1 - 0.054 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Glyco_hydro_35 PF01301.19 KKA01495.1 - 0.21 11.2 4.6 0.077 12.6 1.2 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 Val_tRNA-synt_C PF10458.9 KKA01495.1 - 2.9 8.2 7.3 3.8 7.9 0.8 2.8 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF3502 PF12010.8 KKA01495.1 - 9.9 6.8 10.8 0.57 10.8 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) MKT1_N PF12247.8 KKA01497.1 - 1.6e-10 41.2 0.1 5.1e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication adh_short_C2 PF13561.6 KKA01498.1 - 4.3e-09 36.3 0.0 6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKA01498.1 - 1.7e-08 34.2 0.0 3.8e-07 29.8 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 KKA01498.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 KR domain PDEase_I PF00233.19 KKA01498.1 - 0.053 13.2 0.7 0.38 10.4 0.2 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Med19 PF10278.9 KKA01498.1 - 3.8 7.4 13.7 7.2 6.5 13.7 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Rad4 PF03835.15 KKA01499.1 - 5.5e-13 48.8 2.2 9.4e-13 48.1 0.7 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KKA01499.1 - 2.3e-07 31.2 0.3 9.1e-07 29.3 0.3 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily Zn_Tnp_IS1595 PF12760.7 KKA01499.1 - 0.025 14.5 2.0 0.069 13.1 2.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4264 PF14084.6 KKA01499.1 - 0.028 14.0 0.1 0.066 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DIT1_PvcA PF05141.12 KKA01499.1 - 0.21 11.0 2.8 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein PWWP PF00855.17 KKA01499.1 - 0.5 10.8 2.4 8.6 6.8 0.1 2.7 3 0 0 3 3 3 0 PWWP domain DUF35_N PF12172.8 KKA01499.1 - 3.2 7.7 4.3 1.7 8.6 0.2 2.4 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Desulfoferrod_N PF06397.12 KKA01499.1 - 4.1 7.1 8.1 0.12 12.0 1.9 1.7 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain WLM PF08325.10 KKA01500.1 - 1.3e-46 159.1 0.3 1.6e-46 158.8 0.3 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KKA01500.1 - 0.048 13.7 0.3 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 SprT-like PF10263.9 KKA01500.1 - 0.049 13.5 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 SprT-like family Endosulfine PF04667.17 KKA01502.1 - 6.7e-22 77.4 2.2 6.7e-22 77.4 2.2 1.8 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_M14 PF00246.24 KKA01503.1 - 9.6e-67 225.8 0.2 1.3e-66 225.4 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase UBX PF00789.20 KKA01503.1 - 0.0038 17.4 2.6 1 9.6 0.1 2.6 2 0 0 2 2 2 2 UBX domain Pga1 PF10333.9 KKA01504.1 - 0.048 13.5 0.0 0.048 13.5 0.0 2.2 2 1 0 3 3 3 0 GPI-Mannosyltransferase II co-activator Sigma_reg_N PF13800.6 KKA01505.1 - 7.6 6.9 8.1 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Arginase PF00491.21 KKA01506.1 - 1.2e-87 294.0 0.0 1.5e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KKA01506.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain P16-Arc PF04699.14 KKA01507.1 - 2.3e-20 73.6 0.1 2.8e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ran_BP1 PF00638.18 KKA01508.1 - 2.7e-24 85.8 0.3 6.5e-24 84.5 0.3 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KKA01508.1 - 0.003 17.5 0.2 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 WH1 domain DUF4484 PF14831.6 KKA01508.1 - 0.44 10.6 10.9 0.77 9.8 10.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Methyltransf_31 PF13847.6 KKA01509.1 - 9.6e-16 57.9 0.5 1.5e-15 57.3 0.5 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA01509.1 - 2.9e-05 24.7 1.2 6e-05 23.7 1.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA01509.1 - 0.0013 19.4 0.1 0.0054 17.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA01509.1 - 0.0042 16.9 0.1 0.0082 16.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKA01509.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KKA01509.1 - 0.033 14.9 0.0 0.072 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Fis1_TPR_N PF14852.6 KKA01510.1 - 3.1e-12 45.9 0.0 5.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKA01510.1 - 1.2e-07 31.7 0.1 2.2e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat PUL PF08324.11 KKA01510.1 - 0.032 13.5 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 PUL domain Ribonuc_red_lgC PF02867.15 KKA01511.1 - 1.7e-185 617.5 0.0 2.3e-185 617.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KKA01511.1 - 1.4e-25 89.1 0.0 4.8e-25 87.4 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KKA01511.1 - 6.2e-18 65.1 1.0 4e-17 62.6 0.0 2.9 3 0 0 3 3 3 1 ATP cone domain Sec6 PF06046.13 KKA01512.1 - 1.4e-89 301.0 38.5 2.9e-89 300.0 38.5 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF202 PF02656.15 KKA01513.1 - 9.1e-16 58.1 1.6 1.5e-15 57.4 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CoA_binding_3 PF13727.6 KKA01513.1 - 0.033 14.2 0.8 0.039 14.0 0.8 1.3 1 0 0 1 1 1 0 CoA-binding domain Aldedh PF00171.22 KKA01514.1 - 2.2e-172 573.7 0.0 2.7e-172 573.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKA01514.1 - 0.0092 15.1 0.0 0.022 13.8 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fip1 PF05182.13 KKA01515.1 - 1.4e-13 50.1 1.1 1.4e-13 50.1 1.1 1.9 2 0 0 2 2 2 1 Fip1 motif Myotub-related PF06602.14 KKA01516.1 - 8.1e-89 298.0 5.9 1.2e-88 297.5 5.9 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KKA01516.1 - 0.002 18.0 0.1 0.029 14.2 0.0 3.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KKA01516.1 - 0.0046 16.9 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family TDH PF03347.13 KKA01516.1 - 0.0054 16.3 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Vibrio thermostable direct hemolysin DUF676 PF05057.14 KKA01517.1 - 2.5e-41 141.6 0.2 4.9e-41 140.7 0.2 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KKA01517.1 - 4.4e-05 23.5 0.1 9.1e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KKA01517.1 - 0.027 14.3 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) bZIP_2 PF07716.15 KKA01518.1 - 0.019 15.1 0.9 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Ask1 PF08655.10 KKA01518.1 - 0.13 12.2 7.8 0.22 11.4 0.3 3.4 4 0 0 4 4 4 0 DASH complex subunit Ask1 MSC PF09402.10 KKA01518.1 - 0.15 11.5 0.8 0.2 11.0 0.8 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Nnf1 PF03980.14 KKA01518.1 - 0.18 12.2 2.8 0.24 11.8 1.0 2.2 2 1 0 2 2 2 0 Nnf1 IFT20 PF14931.6 KKA01518.1 - 1.2 9.4 9.1 1.8 8.7 0.4 3.4 3 1 1 4 4 4 0 Intraflagellar transport complex B, subunit 20 VanZ PF04892.12 KKA01519.1 - 5.7e-08 33.5 5.5 7.7e-08 33.0 5.5 1.2 1 0 0 1 1 1 1 VanZ like family Peptidase_M16_C PF05193.21 KKA01521.1 - 1.3e-15 57.9 0.2 2.3e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKA01521.1 - 1.3e-09 38.2 1.9 3.1e-09 37.0 1.9 1.6 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) DUF285 PF03382.14 KKA01521.1 - 1.3 8.8 6.3 12 5.7 0.3 3.3 3 1 0 3 3 3 0 Mycoplasma protein of unknown function, DUF285 PTPLA PF04387.14 KKA01522.1 - 1.3e-43 148.6 6.9 2.1e-43 147.9 6.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L21p PF00829.21 KKA01523.1 - 8.6e-09 35.6 0.3 1.8e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 KKA01524.1 - 1.4e-64 218.0 0.0 2.6e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01524.1 - 6.9e-46 156.6 0.0 1.2e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA01524.1 - 5.5e-07 29.2 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.16 KKA01524.1 - 0.019 14.9 0.3 0.048 13.6 0.3 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain HisG PF01634.18 KKA01525.1 - 2.2e-50 170.7 1.7 3e-50 170.3 1.7 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KKA01525.1 - 2.9e-28 97.8 0.0 5.5e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KKA01525.1 - 0.00015 21.8 0.3 0.00022 21.3 0.3 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Prefoldin PF02996.17 KKA01525.1 - 0.28 11.1 2.7 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit ArfGap PF01412.18 KKA01526.1 - 2.8e-16 59.6 1.8 2.8e-16 59.6 1.8 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf APOBEC1 PF18769.1 KKA01526.1 - 0.06 13.6 0.5 0.18 12.0 0.5 1.8 1 0 0 1 1 1 0 APOBEC1 C1_1 PF00130.22 KKA01526.1 - 0.1 12.5 4.0 0.19 11.7 4.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PIP5K PF01504.18 KKA01527.1 - 2.1e-38 132.2 2.0 1.4e-32 113.0 1.8 3.9 3 1 1 4 4 4 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KKA01527.1 - 3.5e-27 95.2 0.1 6.9e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KKA01527.1 - 6.4e-14 51.8 14.1 1.5e-13 50.7 14.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger RNA_pol_Rpc34 PF05158.12 KKA01528.1 - 2.8e-90 303.1 9.5 3.3e-90 302.9 9.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_46 PF15977.5 KKA01528.1 - 0.098 12.7 0.3 0.098 12.7 0.3 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding DUF4004 PF13171.6 KKA01528.1 - 0.32 11.2 8.4 0.35 11.1 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4004) NusA_N PF08529.11 KKA01528.1 - 2.7 8.4 8.5 1.9 8.9 0.8 2.5 2 1 0 2 2 2 0 NusA N-terminal domain FAD_binding_2 PF00890.24 KKA01530.1 - 1.3e-54 185.9 0.0 2.1e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKA01530.1 - 5.6e-05 22.9 0.0 0.00066 19.4 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKA01530.1 - 8.1e-05 22.0 0.0 0.1 11.8 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKA01530.1 - 0.00017 21.8 0.1 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKA01530.1 - 0.0024 17.2 0.1 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KKA01530.1 - 0.047 12.4 0.1 4.8 5.8 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein DUF676 PF05057.14 KKA01531.1 - 1.2e-30 106.7 2.2 1.2e-30 106.7 2.2 2.9 2 2 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KKA01531.1 - 9.3e-05 22.4 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KKA01531.1 - 0.00011 22.0 0.6 0.00084 19.1 0.1 2.2 2 0 0 2 2 2 1 PGAP1-like protein LRR_8 PF13855.6 KKA01531.1 - 0.35 10.7 2.4 0.91 9.3 0.5 2.6 2 0 0 2 2 2 0 Leucine rich repeat TFB6 PF17110.5 KKA01532.1 - 1.2e-10 41.4 0.0 1.8e-08 34.3 0.0 2.5 1 1 1 2 2 2 2 Subunit 11 of the general transcription factor TFIIH Cupin_8 PF13621.6 KKA01533.1 - 2.6e-37 128.9 0.1 1e-36 127.0 0.1 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KKA01533.1 - 5.1e-05 22.9 0.0 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein ThiF PF00899.21 KKA01535.1 - 1.3e-102 342.3 0.0 1e-71 241.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KKA01535.1 - 1.5e-83 280.6 5.5 1.8e-83 280.3 2.7 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KKA01535.1 - 6.6e-29 100.5 0.5 2e-28 98.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 KKA01535.1 - 2.9e-23 81.9 0.5 1.1e-22 80.0 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KKA01535.1 - 3.5e-19 68.8 1.7 5.2e-19 68.2 0.6 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle GHMP_kinases_N PF00288.26 KKA01536.1 - 1.2e-15 57.5 0.3 2.4e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKA01536.1 - 5.4e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal BCDHK_Adom3 PF10436.9 KKA01536.1 - 0.014 15.3 0.8 0.82 9.5 0.8 2.4 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase NifU_N PF01592.16 KKA01538.1 - 2.6e-57 192.5 0.4 3e-57 192.3 0.4 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KKA01538.1 - 0.09 13.0 0.3 0.16 12.2 0.3 1.4 1 0 0 1 1 1 0 TSCPD domain RNA_pol_Rpb8 PF03870.15 KKA01539.1 - 1.1e-38 132.5 0.0 1.6e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KKA01539.1 - 0.0019 18.2 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF2407_C PF13373.6 KKA01540.1 - 1.2e-08 35.2 12.1 4.8e-06 26.8 7.3 3.0 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KKA01540.1 - 1.2e-08 35.4 0.8 5.3e-08 33.4 0.1 2.6 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain CAS_C PF12026.8 KKA01540.1 - 0.35 10.9 2.4 0.79 9.8 2.4 1.5 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain NOA36 PF06524.12 KKA01540.1 - 1.9 7.7 8.8 3.8 6.7 8.8 1.4 1 0 0 1 1 1 0 NOA36 protein Mito_carr PF00153.27 KKA01541.1 - 2.9e-49 164.9 5.9 9.4e-20 70.3 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 4HPAD_g_N PF18671.1 KKA01541.1 - 0.085 12.6 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal BK_channel_a PF03493.18 KKA01542.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit CtaG_Cox11 PF04442.14 KKA01543.1 - 1.4e-58 197.2 0.6 1.9e-58 196.8 0.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ribosomal_L5e PF17144.4 KKA01544.1 - 4.6e-80 267.3 0.9 5.3e-80 267.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KKA01544.1 - 1.1e-31 109.7 2.7 1.1e-31 109.7 2.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KKA01544.1 - 0.018 15.4 1.2 0.035 14.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 KKA01544.1 - 0.036 14.3 0.1 0.84 9.9 0.0 2.5 1 1 1 2 2 2 0 Threonine synthase N terminus NAC PF01849.18 KKA01544.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NAC domain DPPIV_N PF00930.21 KKA01545.1 - 9.9e-59 198.9 8.6 1.5e-58 198.3 8.6 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KKA01545.1 - 7.6e-44 149.7 0.4 1.3e-43 149.0 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KKA01545.1 - 0.0029 17.3 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KKA01545.1 - 0.005 17.0 0.0 0.0089 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KKA01545.1 - 0.018 15.7 0.0 0.098 13.2 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKA01545.1 - 0.069 12.8 0.0 0.42 10.2 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KKA01545.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ac76 PF05814.11 KKA01545.1 - 0.12 12.4 1.5 0.31 11.1 1.5 1.8 1 0 0 1 1 1 0 Orf76 (Ac76) Hydrolase_4 PF12146.8 KKA01545.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GRAB PF10375.9 KKA01546.1 - 0.00022 21.0 0.2 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 GRIP-related Arf-binding domain CALCOCO1 PF07888.11 KKA01546.1 - 0.00054 19.0 30.5 0.00054 19.0 30.5 2.7 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Herpes_BLRF2 PF05812.12 KKA01546.1 - 0.0015 18.7 1.9 0.0015 18.7 1.9 4.6 2 2 1 4 4 4 1 Herpesvirus BLRF2 protein KASH_CCD PF14662.6 KKA01546.1 - 0.0027 17.6 36.5 0.0027 17.6 36.5 4.2 2 1 2 4 4 4 1 Coiled-coil region of CCDC155 or KASH DUF4164 PF13747.6 KKA01546.1 - 1.2 9.5 33.9 0.46 10.8 4.7 5.4 2 2 3 5 5 5 0 Domain of unknown function (DUF4164) TolA_bind_tri PF16331.5 KKA01546.1 - 4.6 7.4 27.6 3.6 7.7 1.2 5.6 2 2 2 4 4 4 0 TolA binding protein trimerisation Dynamin_N PF00350.23 KKA01547.1 - 5.5e-38 130.7 1.6 5.5e-38 130.7 1.6 3.0 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KKA01547.1 - 0.00017 21.7 1.3 0.0018 18.3 0.3 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKA01547.1 - 0.027 14.8 0.0 0.17 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KKA01547.1 - 0.072 13.3 0.0 0.4 10.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NOA36 PF06524.12 KKA01547.1 - 9.7 5.4 7.1 16 4.7 5.5 1.9 2 0 0 2 2 2 0 NOA36 protein WD40 PF00400.32 KKA01548.1 - 0.25 12.3 2.6 1.4 10.0 0.8 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat NAPRTase PF04095.16 KKA01549.1 - 8.2e-66 222.0 0.1 1.1e-65 221.6 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KKA01549.1 - 1.2e-29 103.2 0.8 2.2e-29 102.4 0.8 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain IBN_N PF03810.19 KKA01550.1 - 6e-08 32.5 4.7 3e-07 30.2 0.3 3.4 3 0 0 3 3 3 2 Importin-beta N-terminal domain Laminin_II PF06009.12 KKA01551.1 - 0.02 14.9 4.8 0.02 14.9 4.8 2.4 2 0 0 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 KKA01551.1 - 2.1 9.0 22.9 2.1 9.0 6.3 3.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KKA01552.1 - 2.1e-07 31.5 1.9 2.1e-07 31.5 1.9 1.9 2 1 0 2 2 2 1 Apg6 coiled-coil region Rpr2 PF04032.16 KKA01552.1 - 0.2 12.0 4.3 0.68 10.2 0.1 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain ABC2_membrane PF01061.24 KKA01553.1 - 2.1e-67 226.6 45.4 1.5e-37 129.1 8.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKA01553.1 - 1.3e-35 122.9 1.5 2.9e-17 63.5 0.1 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KKA01553.1 - 5.3e-26 90.4 12.1 7.2e-22 77.1 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKA01553.1 - 3.4e-06 27.6 0.3 1.5e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKA01553.1 - 9.5e-06 26.1 0.0 0.0064 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKA01553.1 - 0.0017 18.3 0.1 0.042 13.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KKA01553.1 - 0.011 16.0 0.7 0.96 9.7 0.3 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKA01553.1 - 0.017 14.9 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KKA01553.1 - 0.018 15.4 0.0 4.4 7.7 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KKA01553.1 - 0.022 14.4 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKA01553.1 - 0.054 12.8 0.2 0.75 9.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KKA01553.1 - 0.084 12.6 0.3 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKA01553.1 - 0.11 12.6 0.9 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KKA01553.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKA01553.1 - 0.14 11.9 1.5 2.4 8.0 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KKA01553.1 - 0.22 10.6 35.2 0.14 11.2 12.0 3.5 3 1 0 3 3 3 0 ABC-2 family transporter protein DUF2401 PF10287.9 KKA01554.1 - 3.8e-94 314.6 3.6 3.8e-94 314.6 3.6 2.5 2 1 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KKA01554.1 - 9.3e-30 102.9 0.5 2.5e-29 101.5 0.5 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) PTPS PF01242.19 KKA01554.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Amidase PF01425.21 KKA01555.1 - 4.3e-84 283.1 0.0 6.6e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KKA01555.1 - 1.6e-80 270.5 0.0 3.3e-80 269.5 0.0 1.5 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KKA01555.1 - 5.6e-62 209.0 0.0 1.1e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KKA01555.1 - 3.4e-42 144.5 0.0 6.2e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 KKA01555.1 - 1.8e-39 134.7 0.5 4.5e-39 133.4 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKA01555.1 - 1.9e-31 108.4 0.0 6.1e-31 106.7 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKA01555.1 - 3.1e-09 36.5 0.6 1.2e-08 34.7 0.6 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKA01555.1 - 1.7e-08 34.3 0.0 3.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKA01555.1 - 4.3e-05 23.1 0.0 0.00016 21.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKA01555.1 - 0.00093 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain MKRN1_C PF15815.5 KKA01556.1 - 0.088 13.2 0.7 0.35 11.3 0.7 2.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal DUF4889 PF16230.5 KKA01556.1 - 0.12 12.6 7.2 0.43 10.8 1.5 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4889) FtsK_SpoIIIE_N PF12538.8 KKA01556.1 - 0.42 10.8 12.0 0.048 13.9 2.4 2.9 2 1 0 3 3 3 0 DNA transporter Sld5 PF05916.11 KKA01557.1 - 0.00014 22.3 1.3 0.00031 21.2 0.6 2.0 1 1 0 1 1 1 1 GINS complex protein UPF0147 PF03685.13 KKA01557.1 - 0.0097 15.9 2.2 0.29 11.2 2.2 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0147) MCM PF00493.23 KKA01558.1 - 3.4e-100 333.8 0.0 1.1e-99 332.1 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KKA01558.1 - 5.2e-28 97.4 0.9 1e-27 96.5 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKA01558.1 - 7.5e-22 77.6 0.9 1.6e-21 76.5 0.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KKA01558.1 - 1.3e-08 34.4 0.1 3.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKA01558.1 - 9.1e-06 25.7 0.0 3.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 KKA01558.1 - 2.5e-05 24.8 20.6 9.3e-05 23.0 16.3 3.4 2 1 0 2 2 2 1 MCM N-terminal domain AAA_lid_2 PF17863.1 KKA01558.1 - 0.00046 20.0 1.5 0.0012 18.7 0.2 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 KKA01558.1 - 0.0066 16.3 0.0 0.14 12.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKA01558.1 - 0.1 12.9 0.9 3.3 8.1 0.0 3.4 3 1 0 4 4 4 0 AAA ATPase domain Mg_chelatase_C PF13335.6 KKA01558.1 - 1.6 9.4 6.4 0.16 12.6 0.5 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal VPS28 PF03997.12 KKA01559.1 - 1.8e-27 96.3 8.1 3.2e-27 95.4 7.7 1.6 1 1 0 1 1 1 1 VPS28 protein Arginase PF00491.21 KKA01560.1 - 3.8e-66 223.4 0.0 4.4e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF3597 PF12200.8 KKA01560.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) PilM_2 PF11104.8 KKA01560.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; HipN PF18253.1 KKA01561.1 - 0.00078 19.1 0.5 0.01 15.5 0.1 2.8 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain Na_H_Exchanger PF00999.21 KKA01563.1 - 5.5e-53 180.1 12.9 1.4e-30 106.4 2.8 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Actin PF00022.19 KKA01565.1 - 1.6e-53 181.8 0.0 2.4e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKA01565.1 - 0.28 10.0 0.0 0.46 9.2 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein FGGY_C PF02782.16 KKA01566.1 - 3.5e-40 137.8 0.0 6.3e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKA01566.1 - 2.6e-18 66.5 0.2 1e-17 64.5 0.0 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KKA01566.1 - 0.031 13.8 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KKA01566.1 - 0.067 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Transposase Rax2 PF12768.7 KKA01567.1 - 9.9e-10 38.2 3.5 9.9e-10 38.2 3.5 5.9 4 2 2 6 6 6 1 Cortical protein marker for cell polarity SSXT PF05030.12 KKA01568.1 - 0.02 14.5 0.1 0.086 12.5 0.1 2.1 1 0 0 1 1 1 0 SSXT protein (N-terminal region) SSF PF00474.17 KKA01569.1 - 4.4e-13 48.9 28.0 4.4e-13 48.9 28.0 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.9 KKA01569.1 - 0.0029 16.4 1.8 0.0029 16.4 1.8 4.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) GLE1 PF07817.13 KKA01570.1 - 4.8e-50 170.1 0.2 4.8e-50 170.1 0.2 1.7 2 0 0 2 2 2 1 GLE1-like protein Flavokinase PF01687.17 KKA01571.1 - 8.4e-26 90.5 0.0 1.1e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_L5_C PF00673.21 KKA01572.1 - 2.6e-14 53.1 0.0 4.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Cpn60_TCP1 PF00118.24 KKA01573.1 - 4e-156 520.5 3.3 4.5e-156 520.3 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.23 KKA01574.1 - 4e-91 307.0 25.6 4.6e-91 306.8 25.6 1.0 1 0 0 1 1 1 1 Sec1 family CREPT PF16566.5 KKA01574.1 - 0.34 11.1 3.0 1.3 9.2 0.2 3.0 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour SUB1_ProdP9 PF18213.1 KKA01574.1 - 3.3 7.6 8.3 14 5.6 0.4 3.5 4 0 0 4 4 4 0 SUB1 protease Prodomain ProdP9 PRELI PF04707.14 KKA01576.1 - 3.1e-38 131.1 0.5 3.7e-38 130.8 0.5 1.0 1 0 0 1 1 1 1 PRELI-like family DUF4150 PF13665.6 KKA01577.1 - 0.0065 16.6 0.2 3.8 7.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4150) DUF2854 PF11016.8 KKA01577.1 - 0.059 13.3 1.5 0.073 13.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) Sec10 PF07393.11 KKA01578.1 - 3e-13 49.1 52.8 7.1e-12 44.6 52.8 2.6 1 1 0 1 1 1 1 Exocyst complex component Sec10 Mad3_BUB1_I PF08311.12 KKA01578.1 - 0.11 12.4 15.2 0.019 15.0 2.6 4.0 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 Gemini_AL1_M PF08283.11 KKA01578.1 - 4.9 7.3 7.3 1.5 9.0 0.3 3.3 3 0 0 3 3 3 0 Geminivirus rep protein central domain DUF3573 PF12097.8 KKA01579.1 - 0.11 11.3 4.0 0.16 10.8 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SAS4 PF15460.6 KKA01579.1 - 0.39 10.9 15.5 0.16 12.1 10.4 2.9 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Peptidase_M16 PF00675.20 KKA01580.1 - 4.1e-46 156.6 0.1 7.5e-46 155.8 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKA01580.1 - 1.1e-29 103.7 0.1 1.7e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain AbiJ_NTD5 PF18865.1 KKA01580.1 - 0.033 14.0 0.5 4.3 7.2 0.0 3.0 2 1 1 3 3 3 0 AbiJ N-terminal domain 5 MRP-S28 PF10213.9 KKA01581.1 - 2e-06 28.2 0.5 4.7e-06 27.0 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein His_Phos_2 PF00328.22 KKA01582.1 - 3e-38 132.2 0.0 3.8e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KKA01583.1 - 8.3e-40 137.3 0.0 1.2e-39 136.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Katanin_con80 PF13925.6 KKA01584.1 - 0.0021 18.1 3.2 0.026 14.5 0.2 2.6 2 1 0 2 2 2 2 con80 domain of Katanin P22_portal PF16510.5 KKA01584.1 - 0.012 14.2 0.7 0.035 12.7 0.1 1.8 2 0 0 2 2 2 0 Phage P22-like portal protein Antimicrobial_7 PF08102.11 KKA01584.1 - 0.22 11.8 2.9 1.3 9.3 0.8 3.1 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Swi3 PF07962.12 KKA01585.1 - 5.2e-13 48.8 0.3 9.6e-13 47.9 0.3 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 LMBR1 PF04791.16 KKA01585.1 - 3.7 6.3 6.9 4.4 6.1 6.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1657 PF07870.11 KKA01586.1 - 0.22 11.4 0.2 0.22 11.4 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) Matrilin_ccoil PF10393.9 KKA01586.1 - 1.1 9.2 3.8 7.3 6.5 0.5 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Syntaxin-6_N PF09177.11 KKA01586.1 - 2.8 8.5 6.2 0.82 10.3 0.8 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal XPG_N PF00752.17 KKA01587.1 - 1.7e-33 115.1 0.1 4.7e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KKA01587.1 - 6.8e-29 100.1 0.1 6.8e-29 100.1 0.1 2.3 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 KKA01587.1 - 4.6e-05 23.9 0.8 0.00048 20.7 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 KKA01587.1 - 0.00047 19.7 0.2 0.00073 19.0 0.2 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF4407 PF14362.6 KKA01587.1 - 0.012 15.0 1.3 0.017 14.5 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 5_3_exonuc_N PF02739.16 KKA01587.1 - 0.019 14.9 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF1682 PF07946.14 KKA01587.1 - 0.17 11.1 8.4 0.29 10.3 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MRPL52 PF18699.1 KKA01587.1 - 0.5 10.6 8.7 0.81 9.9 8.0 1.8 1 1 0 1 1 1 0 Mitoribosomal protein mL52 OmpH PF03938.14 KKA01587.1 - 8.9 6.7 17.9 20 5.5 17.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AP_endonuc_2 PF01261.24 KKA01588.1 - 1.7e-33 115.9 0.0 2.3e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF3450 PF11932.8 KKA01589.1 - 0.052 12.8 7.4 0.12 11.7 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Porin_OmpG_1_2 PF16946.5 KKA01590.1 - 0.0056 16.0 5.3 0.0066 15.8 5.3 1.1 1 0 0 1 1 1 1 OMPG-porin 1 family Rad17 PF03215.15 KKA01591.1 - 1.7e-05 24.8 5.1 1.7e-05 24.8 5.1 3.5 2 1 0 2 2 2 1 Rad17 P-loop domain dNK PF01712.19 KKA01591.1 - 0.0003 20.7 0.1 0.0003 20.7 0.1 2.4 3 0 0 3 3 3 1 Deoxynucleoside kinase AAA_assoc_2 PF16193.5 KKA01591.1 - 0.0037 17.6 0.1 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA C-terminal domain AAA_18 PF13238.6 KKA01591.1 - 0.007 16.9 2.6 0.014 15.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain ArsC PF03960.15 KKA01591.1 - 0.0079 16.2 0.0 0.04 13.9 0.0 2.3 1 0 0 1 1 1 1 ArsC family AAA PF00004.29 KKA01591.1 - 0.013 15.9 0.1 0.073 13.5 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKA01591.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 KKA01592.1 - 5.8e-05 23.1 16.6 0.00019 21.4 16.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKA01592.1 - 0.037 14.1 17.1 0.085 12.9 17.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Flg_new PF09479.10 KKA01592.1 - 0.04 14.1 0.3 0.04 14.1 0.3 2.2 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) DUF2407_C PF13373.6 KKA01592.1 - 0.073 13.2 4.5 0.12 12.5 4.5 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain GMC_oxred_C PF05199.13 KKA01592.1 - 0.16 12.5 0.6 0.81 10.2 0.6 2.1 1 1 0 1 1 1 0 GMC oxidoreductase Jnk-SapK_ap_N PF09744.9 KKA01592.1 - 0.4 10.9 13.5 0.037 14.2 9.1 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Glutaredoxin2_C PF04399.13 KKA01592.1 - 0.44 10.4 5.4 0.32 10.8 3.2 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain CUE PF02845.16 KKA01593.1 - 7e-09 35.2 5.4 0.0002 21.0 0.4 3.8 3 0 0 3 3 3 3 CUE domain Smr PF01713.21 KKA01593.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain E3_UbLigase_EDD PF11547.8 KKA01593.1 - 0.0084 15.8 0.4 0.023 14.4 0.4 1.8 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD HBS1_N PF08938.10 KKA01593.1 - 0.046 14.0 3.0 0.28 11.5 0.0 2.8 3 0 0 3 3 3 0 HBS1 N-terminus DUF5623 PF18536.1 KKA01593.1 - 0.1 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Tox-ART-HYD1 PF15633.6 KKA01594.1 - 0.44 11.2 3.2 1.1 10.0 0.3 3.2 3 0 0 3 3 3 0 HYD1 signature containing ADP-ribosyltransferase RL10P_insert PF17777.1 KKA01595.1 - 7.9e-20 70.6 0.0 1.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KKA01595.1 - 6.3e-08 32.7 6.9 1e-07 32.0 6.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Phosducin PF02114.16 KKA01595.1 - 0.05 12.5 3.1 0.075 12.0 3.1 1.3 1 0 0 1 1 1 0 Phosducin DUF1965 PF09248.10 KKA01595.1 - 0.15 11.9 0.6 0.39 10.5 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) TRAM_LAG1_CLN8 PF03798.16 KKA01597.1 - 6.5e-37 127.2 27.1 6.5e-37 127.2 27.1 2.3 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 KKA01597.1 - 1.8e-16 59.5 4.4 5.4e-16 58.0 4.4 1.9 1 0 0 1 1 1 1 TRAM1-like protein CENP-C_C PF11699.8 KKA01598.1 - 4e-06 27.0 0.7 1.2e-05 25.4 0.7 1.9 1 1 0 1 1 1 1 Mif2/CENP-C like DUF4749 PF15936.5 KKA01598.1 - 0.017 16.2 0.7 0.072 14.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4749) DUF3395 PF11875.8 KKA01598.1 - 6.1 6.7 12.2 1 9.2 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3395) Snf7 PF03357.21 KKA01599.1 - 5.3e-26 91.3 28.5 6e-26 91.1 25.8 1.9 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 KKA01599.1 - 9.7e-08 32.1 8.5 1.4e-07 31.6 8.5 1.4 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Spore_Cse60 PF10957.8 KKA01599.1 - 0.07 13.2 3.4 0.22 11.6 3.4 1.8 1 0 0 1 1 1 0 Sporulation protein Cse60 WGG PF10273.9 KKA01599.1 - 0.3 11.8 3.8 0.76 10.5 3.8 1.6 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 IFP_35_N PF07334.13 KKA01599.1 - 0.75 9.9 8.3 0.41 10.8 3.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ZapB PF06005.12 KKA01599.1 - 5.3 7.6 13.1 0.98 9.9 5.7 2.6 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KKA01599.1 - 9.9 6.0 12.4 0.77 9.6 5.5 2.5 2 1 0 2 2 2 0 Septum formation initiator APS_kinase PF01583.20 KKA01600.1 - 3.3e-73 244.8 0.0 3.9e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KKA01600.1 - 1.5e-06 28.4 0.0 3.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KKA01600.1 - 9e-05 22.0 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KKA01600.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KKA01600.1 - 0.00024 21.6 0.0 0.00037 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KKA01600.1 - 0.0031 18.0 0.0 0.0035 17.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PRK PF00485.18 KKA01600.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KKA01600.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KKA01600.1 - 0.032 14.7 0.3 0.064 13.8 0.3 1.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KKA01600.1 - 0.061 13.4 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CPT PF07931.12 KKA01600.1 - 0.084 12.7 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Dynamin_M PF01031.20 KKA01601.1 - 3.2e-96 321.9 0.1 3.2e-96 321.9 0.1 1.9 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KKA01601.1 - 5.9e-56 189.1 1.5 1.2e-55 188.1 0.3 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KKA01601.1 - 1.3e-28 99.0 4.6 3.3e-28 97.7 4.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKA01601.1 - 0.0099 16.0 1.8 0.0099 16.0 1.8 2.9 4 1 0 4 4 4 1 50S ribosome-binding GTPase RAC_head PF16717.5 KKA01601.1 - 0.035 15.1 0.3 0.11 13.5 0.3 1.8 1 0 0 1 1 1 0 Ribosome-associated complex head domain AAA_16 PF13191.6 KKA01601.1 - 0.057 13.8 0.0 2.4 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain CHASE6_C PF17150.4 KKA01601.1 - 0.06 14.0 0.0 0.23 12.2 0.0 2.0 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain OAM_alpha PF16552.5 KKA01601.1 - 0.15 12.0 0.1 43 4.0 0.0 3.3 3 0 0 3 3 3 0 D-ornithine 4,5-aminomutase alpha-subunit 3H PF02829.14 KKA01601.1 - 4.4 7.7 6.0 4.8 7.6 0.4 3.0 2 1 0 2 2 2 0 3H domain PAP_central PF04928.17 KKA01602.1 - 5.2e-100 333.5 0.0 7.7e-100 333.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KKA01602.1 - 8.7e-39 132.9 1.5 1.7e-38 131.9 1.5 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KKA01602.1 - 1.6e-11 44.4 0.0 5e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KKA01602.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 KKA01602.1 - 0.0043 17.1 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase KIP1 PF07765.12 KKA01602.1 - 2.6 8.3 4.7 13 6.0 0.6 2.6 2 0 0 2 2 2 0 KIP1-like protein Oxysterol_BP PF01237.18 KKA01603.1 - 1.4e-83 280.8 0.3 6.1e-73 245.8 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein LAMTOR PF15454.6 KKA01605.1 - 0.0099 16.5 9.9 0.0099 16.5 9.9 2.3 2 1 1 3 3 3 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UBA_4 PF14555.6 KKA01605.1 - 0.031 14.1 0.3 7 6.6 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain Bromodomain PF00439.25 KKA01606.1 - 1.6e-27 95.3 6.9 2.7e-19 69.0 0.9 2.7 2 0 0 2 2 2 2 Bromodomain UTP15_C PF09384.10 KKA01609.1 - 2e-19 69.7 0.0 2.5e-18 66.2 0.1 2.4 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 KKA01609.1 - 5.3e-11 42.9 0.4 0.0018 19.1 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA01609.1 - 1.2e-06 28.8 0.0 0.0056 16.9 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KKA01609.1 - 0.11 12.5 0.6 14 5.7 0.0 4.1 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region DivIC PF04977.15 KKA01610.1 - 0.71 9.7 2.9 2.3 8.0 2.9 1.9 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.25 KKA01611.1 - 9.9e-68 228.4 0.0 1.5e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01611.1 - 8.7e-33 113.7 0.0 4.2e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 KKA01611.1 - 1.5e-10 41.6 2.9 2.1e-10 41.2 1.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KKA01611.1 - 2.3e-06 26.8 0.3 5e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKA01611.1 - 0.00082 18.8 0.0 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KKA01611.1 - 0.0012 18.5 0.1 0.44 10.1 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KKA01611.1 - 0.05 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKA01611.1 - 0.093 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF489 PF04356.12 KKA01612.1 - 0.07 13.1 1.3 0.09 12.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Nab2 PF11517.8 KKA01612.1 - 0.078 13.3 0.3 0.078 13.3 0.3 2.2 2 1 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) RecG_N PF17190.4 KKA01612.1 - 0.66 10.7 0.1 0.66 10.7 0.1 3.5 2 1 2 4 4 4 0 RecG N-terminal helical domain Rad10 PF03834.14 KKA01612.1 - 1.1 9.4 7.5 1.4 8.9 1.8 3.2 2 1 2 4 4 4 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Ribosomal_L3 PF00297.22 KKA01613.1 - 5.8e-22 78.2 0.2 3.3e-19 69.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 CRM1_C PF08767.11 KKA01614.1 - 3.2e-120 401.1 6.2 3.2e-120 401.1 6.2 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KKA01614.1 - 9.9e-37 126.3 8.1 9.9e-37 126.3 8.1 5.8 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KKA01614.1 - 5.2e-30 102.9 1.0 1.5e-29 101.4 1.0 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KKA01614.1 - 1.1e-27 95.8 1.5 1.9e-26 91.9 0.9 3.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KKA01614.1 - 8.1e-17 60.4 0.4 2.9e-16 58.7 0.4 2.1 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KKA01614.1 - 2.1e-16 59.6 1.2 9.3e-16 57.5 0.2 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Symplekin_C PF12295.8 KKA01614.1 - 0.0012 18.9 6.5 2 8.5 0.0 4.8 4 1 0 4 4 4 2 Symplekin tight junction protein C terminal Tipalpha PF16753.5 KKA01614.1 - 0.0083 16.0 2.5 0.88 9.4 0.1 3.5 3 0 0 3 3 3 1 TNF-alpha-Inducing protein of Helicobacter ANAPC2 PF08672.11 KKA01614.1 - 0.024 15.2 0.3 0.13 12.8 0.1 2.5 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Peripla_BP_7 PF18610.1 KKA01614.1 - 0.064 13.4 0.8 12 6.1 0.0 3.9 3 0 0 3 3 3 0 Periplasmic binding protein domain Frag1 PF10277.9 KKA01615.1 - 7e-41 140.2 20.1 1e-40 139.6 20.1 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4191 PF13829.6 KKA01615.1 - 0.061 12.6 2.3 0.18 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TMCO5 PF14992.6 KKA01615.1 - 0.19 11.3 0.4 0.31 10.6 0.4 1.3 1 0 0 1 1 1 0 TMCO5 family Histone PF00125.24 KKA01616.1 - 1.8e-32 112.5 3.0 1.8e-32 112.5 3.0 1.7 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KKA01616.1 - 0.0024 18.0 0.3 0.0063 16.6 0.0 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Peptidase_M32 PF02074.15 KKA01616.1 - 0.0067 15.3 1.4 0.0078 15.0 1.4 1.1 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase CENP-S PF15630.6 KKA01616.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 CENP-S protein DUF3552 PF12072.8 KKA01617.1 - 0.0021 17.5 11.8 0.013 15.0 2.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) Eisosome1 PF12757.7 KKA01618.1 - 1.6e-10 41.3 0.2 1.6e-10 41.3 0.2 5.2 5 2 1 6 6 6 2 Eisosome protein 1 SlyX PF04102.12 KKA01618.1 - 0.079 13.6 13.8 0.66 10.6 0.3 4.3 3 0 0 3 3 3 0 SlyX zf-C2H2 PF00096.26 KKA01619.1 - 1e-22 79.2 30.0 2.4e-06 27.7 1.1 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA01619.1 - 2.3e-19 68.9 20.2 1.5e-07 31.6 0.5 4.9 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA01619.1 - 5.2e-11 42.4 35.3 6.1e-05 23.5 0.5 5.4 6 0 0 6 6 4 4 C2H2-type zinc finger zf-met PF12874.7 KKA01619.1 - 2.2e-05 24.7 15.6 0.039 14.4 0.3 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKA01619.1 - 5.1e-05 23.4 11.1 0.71 10.2 2.0 4.5 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KKA01619.1 - 0.0028 17.6 19.8 0.11 12.6 2.1 4.3 3 1 1 4 4 4 3 BED zinc finger zf-C2H2_6 PF13912.6 KKA01619.1 - 0.0061 16.5 24.9 0.12 12.4 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 KKA01619.1 - 0.01 16.1 6.4 0.026 14.8 0.9 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KKA01619.1 - 0.025 14.2 5.3 7.2 6.3 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KKA01619.1 - 0.093 12.6 0.5 9.7 6.1 0.0 2.7 1 1 1 2 2 2 0 GAGA factor PyrI_C PF02748.15 KKA01619.1 - 0.12 12.3 4.0 0.86 9.6 0.3 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.6 KKA01619.1 - 0.13 12.0 6.8 3.1 7.6 0.9 3.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain C1_1 PF00130.22 KKA01619.1 - 0.27 11.1 6.1 0.7 9.8 0.8 2.6 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_SprT PF17283.2 KKA01619.1 - 0.27 11.2 2.3 0.41 10.6 0.2 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 KKA01619.1 - 0.34 11.0 4.0 0.87 9.7 4.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-MYST PF17772.1 KKA01619.1 - 0.44 10.2 3.4 1.9 8.2 0.5 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf-Dof PF02701.15 KKA01619.1 - 0.84 9.8 9.8 0.99 9.6 0.3 3.8 1 1 3 4 4 4 0 Dof domain, zinc finger zinc_ribbon_15 PF17032.5 KKA01619.1 - 1.1 10.1 5.7 0.84 10.4 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KKA01619.1 - 8.8 6.5 7.6 9.4 6.4 3.5 2.6 1 1 2 3 3 3 0 Zinc ribbon domain SH3_1 PF00018.28 KKA01620.1 - 3.5e-21 74.5 0.1 5.1e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KKA01620.1 - 1.8e-19 69.3 0.1 7.1e-10 38.6 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KKA01620.1 - 4e-09 36.0 0.0 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KKA01620.1 - 0.0077 16.5 1.5 0.059 13.7 0.0 3.0 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_10 PF17902.1 KKA01620.1 - 0.032 14.3 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 SH3 domain DUF3811 PF11656.8 KKA01620.1 - 0.31 11.5 5.6 0.16 12.3 1.8 2.6 2 0 0 2 2 2 0 YjbD family (DUF3811) AI-2E_transport PF01594.16 KKA01620.1 - 1.3 8.1 4.7 0.43 9.7 0.5 2.0 2 0 0 2 2 2 0 AI-2E family transporter Baculo_PEP_C PF04513.12 KKA01620.1 - 1.5 8.9 25.9 0.022 14.8 9.1 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCM_N PF14551.6 KKA01620.1 - 4.1 8.0 7.1 1.2 9.7 1.3 3.0 2 1 1 3 3 3 0 MCM N-terminal domain Maf PF02545.14 KKA01621.1 - 2.1e-29 102.5 0.0 2.5e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein DUF1465 PF07323.12 KKA01622.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) TSC22 PF01166.18 KKA01622.1 - 0.39 11.1 4.3 0.31 11.4 1.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family SNAPc19 PF15497.6 KKA01622.1 - 0.79 10.2 10.2 0.13 12.7 5.1 2.5 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DNA_pol_B PF00136.21 KKA01623.1 - 1.4e-115 386.7 10.7 2.2e-115 386.0 10.7 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KKA01623.1 - 1.2e-36 126.3 10.3 2.8e-36 125.0 10.3 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KKA01623.1 - 2.8e-23 82.6 5.5 2.8e-23 82.6 5.5 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Aa_trans PF01490.18 KKA01624.1 - 1.3e-89 300.8 37.3 1.5e-89 300.6 37.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KKA01624.1 - 1e-12 47.6 37.6 1.2e-12 47.4 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KKA01624.1 - 1.7 7.4 39.0 0.25 10.1 32.0 2.1 2 0 0 2 2 2 0 Spore germination protein CDP-OH_P_transf PF01066.21 KKA01624.1 - 3.6 8.4 6.3 5.9 7.7 1.3 3.5 2 2 0 2 2 2 0 CDP-alcohol phosphatidyltransferase PS_Dcarbxylase PF02666.15 KKA01625.1 - 5.1e-67 225.3 0.0 7.4e-67 224.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sugar_tr PF00083.24 KKA01626.1 - 2.2e-132 442.2 28.4 2.6e-132 441.9 28.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA01626.1 - 3e-21 75.8 33.5 1.4e-19 70.3 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DctQ PF04290.12 KKA01626.1 - 0.76 9.7 10.7 6 6.8 1.4 4.0 4 1 0 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sugar_tr PF00083.24 KKA01627.1 - 1.8e-148 495.2 27.8 2e-148 495.0 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA01627.1 - 2.6e-27 95.7 31.4 1e-24 87.2 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 KKA01627.1 - 3.1 7.4 7.2 2.8 7.5 3.6 2.8 3 1 0 3 3 3 0 Prokaryotic cytochrome b561 Adenylsucc_synt PF00709.21 KKA01628.1 - 5.1e-172 572.5 0.0 5.8e-172 572.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Hydrolase_6 PF13344.6 KKA01629.1 - 4e-27 94.3 0.0 6.3e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKA01629.1 - 9.9e-13 48.9 0.0 1.6e-12 48.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKA01629.1 - 3.4e-12 46.3 0.0 5.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KKA01629.1 - 0.0019 18.3 0.4 1.1 9.3 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Tfb5 PF06331.12 KKA01629.1 - 0.11 12.5 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 MgsA_C PF12002.8 KKA01630.1 - 2.4e-49 167.5 0.0 4.3e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.12 KKA01630.1 - 1.1e-11 44.7 0.0 3e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KKA01630.1 - 4.1e-10 40.2 0.0 7.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 KKA01630.1 - 2.2e-09 37.5 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KKA01630.1 - 0.00025 21.5 0.0 0.0013 19.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KKA01630.1 - 0.00093 19.2 3.7 0.0021 18.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KKA01630.1 - 0.0026 17.7 0.1 0.021 14.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sgf11 PF08209.11 KKA01630.1 - 0.0027 17.2 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) ATPase_2 PF01637.18 KKA01630.1 - 0.0047 16.9 0.7 0.27 11.1 0.0 2.5 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KKA01630.1 - 0.0094 15.7 0.1 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 KKA01630.1 - 0.021 14.0 0.1 0.053 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKA01630.1 - 0.027 14.7 0.2 8.1 6.7 0.0 2.6 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KKA01630.1 - 0.048 13.1 0.2 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KKA01630.1 - 0.08 13.3 0.0 0.4 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain zf_UBZ PF18439.1 KKA01630.1 - 0.085 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger AAA_24 PF13479.6 KKA01630.1 - 0.098 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rap1-DNA-bind PF09197.10 KKA01631.1 - 1.2e-17 64.4 0.1 4.7e-14 52.9 0.0 3.6 2 2 0 2 2 2 2 Rap1, DNA-binding Myb_DNA-bind_2 PF08914.11 KKA01631.1 - 1e-07 32.0 1.7 0.00098 19.3 0.1 2.9 3 0 0 3 3 3 2 Rap1 Myb domain Myb_DNA-binding PF00249.31 KKA01631.1 - 1e-07 32.0 0.4 2.6e-06 27.5 0.0 3.2 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA01631.1 - 0.00055 20.1 0.6 0.0019 18.4 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain PAPA-1 PF04795.12 KKA01632.1 - 1.2e-06 29.2 7.1 1.2e-06 29.2 7.1 3.0 1 1 2 3 3 3 1 PAPA-1-like conserved region LIM_bind PF01803.16 KKA01633.1 - 2e-26 93.0 9.6 1.8e-16 60.4 1.1 2.4 2 0 0 2 2 2 2 LIM-domain binding protein MTS PF05175.14 KKA01634.1 - 8.4e-07 28.7 0.1 6.2e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KKA01634.1 - 2.9e-06 26.9 0.0 4.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KKA01634.1 - 0.00025 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA01634.1 - 0.0014 19.3 0.0 0.0041 17.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 KKA01634.1 - 0.018 14.3 0.2 0.047 12.9 0.2 1.7 1 1 0 1 1 1 0 N-6 DNA Methylase Glyco_hydro_81 PF03639.13 KKA01634.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain Aida_C2 PF14186.6 KKA01634.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal adhesion Ubie_methyltran PF01209.18 KKA01634.1 - 0.076 12.3 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmC_N PF17827.1 KKA01634.1 - 0.15 12.6 0.0 0.37 11.4 0.0 1.6 1 1 0 1 1 1 0 PrmC N-terminal domain Methyltr_RsmB-F PF01189.17 KKA01635.1 - 9.7e-80 266.9 0.0 2.2e-79 265.7 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KKA01635.1 - 1.2e-08 35.3 0.0 4.3e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KKA01635.1 - 0.0036 17.1 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2431 PF10354.9 KKA01635.1 - 0.02 15.2 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) PCMT PF01135.19 KKA01635.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L17 PF01196.19 KKA01635.1 - 0.096 13.6 0.1 0.36 11.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L17 AroM PF07302.11 KKA01635.1 - 0.16 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 AroM protein S-methyl_trans PF02574.16 KKA01636.1 - 1.5e-42 146.3 0.0 1.8e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Linker_histone PF00538.19 KKA01636.1 - 0.077 13.4 0.9 1.9 8.9 0.0 2.7 2 1 1 3 3 3 0 linker histone H1 and H5 family Ras PF00071.22 KKA01637.1 - 1.4e-52 177.5 0.3 1.9e-52 177.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA01637.1 - 2.2e-20 73.1 0.0 3.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA01637.1 - 2.6e-07 30.3 0.1 5.4e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKA01637.1 - 0.0004 19.8 0.1 0.00047 19.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKA01637.1 - 0.0058 16.2 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Aminotran_1_2 PF00155.21 KKA01639.1 - 7.6e-59 199.7 0.0 8.9e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NlpE PF04170.12 KKA01640.1 - 0.11 13.5 7.7 0.98 10.4 0.0 4.2 4 0 0 4 4 4 0 NlpE N-terminal domain Vac7 PF12751.7 KKA01641.1 - 1e-12 48.3 0.6 1e-12 48.3 0.6 6.1 3 2 3 6 6 6 1 Vacuolar segregation subunit 7 p450 PF00067.22 KKA01642.1 - 3.4e-25 88.7 1.5 6.5e-16 58.1 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ank_2 PF12796.7 KKA01643.1 - 1.1e-30 106.0 0.4 1.3e-13 51.3 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKA01643.1 - 7.8e-18 64.6 0.8 4.2e-09 36.8 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKA01643.1 - 3e-17 62.5 0.2 1.9e-10 40.8 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA01643.1 - 4.7e-13 48.1 1.3 0.00011 22.3 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KKA01643.1 - 3.9e-09 36.5 0.1 0.00022 21.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat COX4 PF02936.14 KKA01644.1 - 1.1e-27 96.7 0.0 1.4e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Methyltransf_16 PF10294.9 KKA01645.1 - 5.5e-07 29.5 0.6 0.017 14.8 0.3 2.3 1 1 1 2 2 2 2 Lysine methyltransferase DUF2183 PF09949.9 KKA01646.1 - 5.3e-26 90.8 0.2 2.5e-25 88.7 0.2 2.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF3755 PF12579.8 KKA01646.1 - 0.38 10.4 5.7 0.1 12.2 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) PP2C PF00481.21 KKA01647.1 - 4.9e-42 144.3 0.0 8.9e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KKA01647.1 - 0.00086 19.3 0.0 0.73 9.7 0.0 3.1 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Arf PF00025.21 KKA01648.1 - 1.2e-11 44.4 2.7 1.2e-11 44.4 2.7 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Peptidase_M16_C PF05193.21 KKA01648.1 - 0.029 14.4 1.7 0.08 12.9 1.5 2.1 1 1 0 1 1 1 0 Peptidase M16 inactive domain XPG_N PF00752.17 KKA01648.1 - 0.043 14.3 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 XPG N-terminal domain SpoOE-like PF09388.10 KKA01648.1 - 0.048 13.6 0.3 0.83 9.6 0.0 2.7 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein HA2 PF04408.23 KKA01651.1 - 8.2e-21 74.3 0.0 8.2e-21 74.3 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKA01651.1 - 5.2e-20 71.6 0.0 2.7e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKA01651.1 - 3.9e-14 52.9 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA01651.1 - 3e-10 40.1 0.5 6.7e-10 39.0 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.6 KKA01651.1 - 1.3e-06 29.1 1.7 0.0034 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKA01651.1 - 1e-05 25.8 0.0 3.3e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKA01651.1 - 5e-05 23.7 0.4 0.00018 21.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KKA01651.1 - 9.8e-05 22.1 0.2 0.00036 20.2 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KKA01651.1 - 0.00013 22.0 0.4 0.00026 21.0 0.4 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 KKA01651.1 - 0.0015 18.5 0.2 0.11 12.5 0.2 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKA01651.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKA01651.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 KKA01651.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KKA01651.1 - 0.087 12.3 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_L28 PF00830.19 KKA01652.1 - 0.001 19.2 0.0 0.0034 17.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L28 family zf-CCCH_2 PF14608.6 KKA01653.1 - 2.5e-20 72.1 60.9 0.00025 21.4 1.2 7.4 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KKA01653.1 - 4.8e-12 46.1 0.1 9.8e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Nab2p_Zf1 PF18260.1 KKA01653.1 - 0.00032 20.5 0.3 0.00032 20.5 0.3 3.6 3 0 0 3 3 3 2 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Glyco_hydro_31 PF01055.26 KKA01654.1 - 2.5e-112 376.3 5.1 5e-112 375.3 5.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKA01654.1 - 1.8e-18 66.6 4.6 8.6e-18 64.4 0.0 4.0 5 0 0 5 5 5 1 Galactose mutarotase-like DUF5110 PF17137.4 KKA01654.1 - 0.003 17.8 4.2 0.0045 17.2 0.7 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5110) PIR PF00399.19 KKA01655.1 - 2.8e-39 131.8 77.5 1e-08 34.5 5.5 6.2 5 0 0 5 5 5 5 Yeast PIR protein repeat TFIIA PF03153.13 KKA01655.1 - 1.1 9.1 15.4 1.4 8.8 15.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 KKA01655.1 - 2.9 7.7 7.2 3.7 7.4 7.2 1.3 1 0 0 1 1 1 0 SPX domain PigN PF04987.14 KKA01656.1 - 1.8e-120 402.9 53.7 2.6e-120 402.4 53.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KKA01656.1 - 1.3e-10 41.5 0.2 1.7e-06 27.9 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKA01656.1 - 2e-09 37.3 0.2 3.8e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KKA01656.1 - 1.8e-05 24.3 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily SRP1_TIP1 PF00660.17 KKA01657.1 - 0.023 14.8 0.4 0.046 13.8 0.4 1.4 1 0 0 1 1 1 0 Seripauperin and TIP1 family PH_10 PF15411.6 KKA01657.1 - 0.11 12.7 2.8 0.3 11.4 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.25 KKA01658.1 - 3.2e-71 239.8 0.1 4.6e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01658.1 - 2.9e-36 125.1 0.0 4.3e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA01658.1 - 1e-07 31.6 0.0 2.9e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like ORF6N PF10543.9 KKA01659.1 - 0.11 12.7 1.5 0.26 11.5 0.2 2.3 2 0 0 2 2 2 0 ORF6N domain MARVEL PF01284.23 KKA01659.1 - 0.13 12.3 7.9 0.23 11.5 7.9 1.3 1 0 0 1 1 1 0 Membrane-associating domain Nramp PF01566.18 KKA01661.1 - 3.9e-78 262.9 17.9 5.6e-78 262.4 17.9 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein HA2 PF04408.23 KKA01662.1 - 4e-21 75.3 0.0 4e-21 75.3 0.0 4.0 4 2 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKA01662.1 - 1.6e-14 54.2 1.0 1e-12 48.4 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KKA01662.1 - 7.8e-11 42.2 0.0 1.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KKA01662.1 - 5.5e-09 36.0 0.1 5.5e-09 36.0 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKA01662.1 - 4.3e-06 27.0 1.3 7.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKA01662.1 - 0.003 17.9 0.1 0.0074 16.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKA01662.1 - 0.0049 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KKA01662.1 - 0.018 14.5 0.0 0.048 13.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KKA01662.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nore1-SARAH PF16517.5 KKA01662.1 - 0.72 9.8 10.1 0.53 10.2 2.1 3.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain ATPase PF06745.13 KKA01662.1 - 6 6.1 19.4 0.052 12.9 0.6 4.3 3 1 1 4 4 4 0 KaiC MOZ_SAS PF01853.18 KKA01663.1 - 2.2e-37 128.4 4.2 9.3e-37 126.4 4.2 1.9 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKA01663.1 - 2.5e-06 27.0 1.1 9.8e-06 25.1 1.1 2.1 1 0 0 1 1 1 1 MYST family zinc finger domain zf-CpG_bind_C PF12269.8 KKA01663.1 - 0.037 13.8 1.0 0.079 12.7 0.2 1.8 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain PNGaseA PF12222.8 KKA01664.1 - 6.3e-82 275.7 1.8 6.3e-82 275.7 1.8 1.5 2 0 0 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A NOGCT PF08155.11 KKA01664.1 - 0.0019 18.1 0.5 0.0073 16.3 0.1 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain CPL PF08144.11 KKA01666.1 - 3.7e-33 114.9 9.2 5.2e-31 107.9 0.2 4.8 3 1 1 4 4 4 1 CPL (NUC119) domain SatD PF16264.5 KKA01666.1 - 0.0024 17.5 1.1 0.28 10.7 0.1 2.8 2 0 0 2 2 2 2 SatD family (SatD) PUF PF00806.19 KKA01666.1 - 0.004 16.8 5.6 1.1 9.1 0.0 5.4 6 0 0 6 6 6 1 Pumilio-family RNA binding repeat DBP10CT PF08147.12 KKA01666.1 - 0.038 14.2 1.0 1.3 9.4 0.0 3.3 3 0 0 3 3 3 0 DBP10CT (NUC160) domain SAC3 PF12209.8 KKA01666.1 - 0.31 11.2 2.4 59 3.9 0.0 4.4 3 1 1 4 4 4 0 Leucine permease transcriptional regulator helical domain MU2_FHA PF18221.1 KKA01667.1 - 0.029 14.4 0.0 2.3 8.3 0.0 2.4 1 1 1 2 2 2 0 Mutator 2 Fork head associated domain Ctr PF04145.15 KKA01668.1 - 3.7e-13 50.4 11.3 8.9e-13 49.1 10.3 2.2 1 1 0 1 1 1 1 Ctr copper transporter family Pex24p PF06398.11 KKA01668.1 - 0.053 12.5 1.9 0.069 12.1 0.0 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Glyco_hydro_15 PF00723.21 KKA01669.1 - 2.3e-55 188.2 0.3 3.5e-55 187.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF4231 PF14015.6 KKA01669.1 - 0.11 13.0 0.3 18 5.8 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Ribul_P_3_epim PF00834.19 KKA01670.1 - 5.2e-70 234.9 0.1 6.4e-70 234.6 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family JmjN PF02375.17 KKA01670.1 - 0.02 14.9 0.0 0.07 13.1 0.0 1.9 2 0 0 2 2 2 0 jmjN domain ThiG PF05690.14 KKA01670.1 - 0.043 13.1 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KKA01670.1 - 0.057 13.0 0.2 0.093 12.3 0.2 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PG_binding_3 PF09374.10 KKA01670.1 - 0.068 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.19 KKA01670.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Glyoxalase PF00903.25 KKA01670.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF5427 PF10310.9 KKA01671.1 - 6.7e-48 163.8 22.6 5.9e-46 157.4 22.6 2.8 1 1 0 1 1 1 1 Family of unknown function (DUF5427) DUF2281 PF10047.9 KKA01671.1 - 0.012 16.3 4.0 28 5.5 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2281) Snf7 PF03357.21 KKA01672.1 - 1.6e-22 79.9 23.5 2.1e-22 79.5 23.5 1.1 1 0 0 1 1 1 1 Snf7 Glycos_transf_3 PF00591.21 KKA01672.1 - 0.14 11.7 2.4 0.36 10.4 1.4 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, a/b domain GIDA_assoc PF13932.6 KKA01672.1 - 0.4 10.8 8.4 0.48 10.6 8.4 1.2 1 0 0 1 1 1 0 GidA associated domain YL1 PF05764.13 KKA01673.1 - 9.4e-31 107.8 35.4 9.4e-31 107.8 35.4 2.1 2 0 0 2 2 2 2 YL1 nuclear protein Aha1_N PF09229.11 KKA01674.1 - 4.8e-27 94.8 0.4 5.5e-27 94.6 0.4 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF4830 PF16112.5 KKA01675.1 - 0.002 18.6 0.1 0.0042 17.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4830) Sec20 PF03908.13 KKA01676.1 - 2.4e-24 85.1 2.6 2.4e-24 85.1 2.6 4.3 5 0 0 5 5 5 2 Sec20 Phage_antitermQ PF06530.12 KKA01676.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Phage antitermination protein Q MatP_C PF17414.2 KKA01676.1 - 3.3 8.0 9.6 0.77 10.0 0.6 3.6 4 0 0 4 4 4 0 MatP C-terminal ribbon-helix-helix domain tRNA-synt_1b PF00579.25 KKA01677.1 - 8e-21 74.6 0.0 2.4e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) DUF2491 PF10679.9 KKA01677.1 - 0.048 12.8 0.1 0.086 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) SLD5_C PF16922.5 KKA01678.1 - 1.7e-12 47.3 1.2 3.1e-12 46.5 1.2 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KKA01678.1 - 1.3e-07 32.0 4.4 1.8e-07 31.6 3.4 1.8 2 0 0 2 2 2 1 GINS complex protein HlyIII PF03006.20 KKA01680.1 - 2.1e-52 178.0 21.9 2.7e-52 177.7 21.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF981 PF06168.11 KKA01680.1 - 0.011 15.7 3.1 0.19 11.6 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF981) DUF2684 PF10885.8 KKA01680.1 - 0.17 12.0 8.2 1.2 9.3 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2684) VEGFR-2_TMD PF17988.1 KKA01680.1 - 1.5 8.3 5.2 22 4.6 0.1 2.6 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Peptidase_C25_C PF03785.14 KKA01681.1 - 0.019 14.8 4.9 0.019 14.8 4.9 2.7 2 1 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain CUTL PF16557.5 KKA01681.1 - 3.3 8.0 6.8 0.26 11.5 0.4 2.5 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB Helicase_C PF00271.31 KKA01682.1 - 1.4e-15 57.6 2.1 3.3e-15 56.4 0.4 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.23 KKA01682.1 - 3.1e-12 46.7 0.0 8.2e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KKA01682.1 - 3e-06 27.1 0.7 6.2e-06 26.1 0.7 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKA01682.1 - 6.1e-05 23.3 0.1 0.00014 22.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KKA01682.1 - 0.00023 21.1 0.0 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 1 Helicase OB_NTP_bind PF07717.16 KKA01682.1 - 0.002 18.5 0.3 0.0082 16.5 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold IstB_IS21 PF01695.17 KKA01682.1 - 0.0027 17.4 0.0 0.76 9.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 KKA01682.1 - 0.024 14.1 0.1 0.06 12.8 0.1 1.8 1 1 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KKA01682.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KKA01682.1 - 0.031 14.6 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKA01682.1 - 0.033 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KKA01682.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PH_2 PF08458.10 KKA01682.1 - 0.038 14.3 0.1 1.3 9.4 0.0 3.1 2 1 0 2 2 2 0 Plant pleckstrin homology-like region AAA_29 PF13555.6 KKA01682.1 - 0.039 13.7 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KKA01682.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KKA01682.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 KKA01682.1 - 0.24 11.4 9.8 0.04 13.9 3.9 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KKA01682.1 - 1.6 8.7 7.9 3.4 7.7 2.7 3.2 2 1 0 2 2 2 0 AAA domain PFK PF00365.20 KKA01683.1 - 4.8e-183 606.9 6.7 7.1e-103 343.8 2.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KKA01683.1 - 0.007 16.0 0.1 0.12 11.9 0.0 2.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain UVR PF02151.19 KKA01683.1 - 0.073 12.8 0.9 0.15 11.8 0.9 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Glyco_hyd_101C PF17451.2 KKA01684.1 - 0.043 14.1 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Imm27 PF15590.6 KKA01684.1 - 0.073 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 27 Mss4 PF04421.13 KKA01686.1 - 1.7e-15 56.9 0.1 2.2e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Mss4 protein Ribosomal_S3Ae PF01015.18 KKA01686.1 - 0.026 14.1 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family eIF-6 PF01912.18 KKA01687.1 - 2.8e-80 268.3 1.2 3.6e-80 268.0 1.2 1.1 1 0 0 1 1 1 1 eIF-6 family PI3_PI4_kinase PF00454.27 KKA01688.1 - 1e-37 130.3 5.5 5.4e-36 124.7 0.1 4.1 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KKA01688.1 - 4e-17 62.2 0.2 1.7e-16 60.2 0.2 2.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) AAA_18 PF13238.6 KKA01688.1 - 0.0052 17.3 0.3 0.029 14.9 0.3 2.3 1 0 0 1 1 1 1 AAA domain Aconitase PF00330.20 KKA01689.1 - 1.9e-148 495.3 0.0 2.4e-148 495.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKA01689.1 - 3.8e-45 153.4 0.0 7e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Como_SCP PF02248.16 KKA01689.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Small coat protein Cys_Met_Meta_PP PF01053.20 KKA01690.1 - 4.1e-146 486.4 0.0 4.6e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KKA01690.1 - 1.5e-10 40.8 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKA01690.1 - 2.7e-09 36.5 0.1 4.3e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKA01690.1 - 6e-09 35.7 0.0 9.5e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KKA01690.1 - 0.00022 19.9 0.1 0.00035 19.2 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KKA01690.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Asparaginase_C PF17763.1 KKA01690.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain ABC_tran PF00005.27 KKA01691.1 - 1.2e-15 58.2 0.0 4e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KKA01691.1 - 0.001 18.7 0.0 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ploopntkinase1 PF18748.1 KKA01691.1 - 0.0049 16.4 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 SMC_N PF02463.19 KKA01691.1 - 0.0098 15.3 2.3 2.8 7.3 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KKA01691.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3143 PF11341.8 KKA01691.1 - 0.18 12.2 0.4 70 3.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3143) Aminotran_1_2 PF00155.21 KKA01692.1 - 9.5e-63 212.5 0.0 1.3e-62 212.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKA01692.1 - 0.0004 19.5 0.0 0.00061 18.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KKA01692.1 - 0.0035 16.1 0.0 0.0073 15.1 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KKA01692.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKA01692.1 - 0.15 11.3 0.0 0.51 9.6 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cofilin_ADF PF00241.20 KKA01693.1 - 3.2e-13 49.5 0.6 4.3e-13 49.1 0.6 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AHJR-like PF18743.1 KKA01693.1 - 0.075 12.6 0.6 0.1 12.2 0.1 1.5 2 0 0 2 2 2 0 REase_AHJR-like Pectate_lyase22 PF14583.6 KKA01695.1 - 0.014 14.1 0.2 0.019 13.7 0.2 1.1 1 0 0 1 1 1 0 Oligogalacturonate lyase DUF747 PF05346.11 KKA01696.1 - 7.5e-41 140.6 25.5 1.4e-40 139.7 25.5 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4643 PF15485.6 KKA01696.1 - 0.21 11.4 0.1 0.3 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) DUF983 PF06170.12 KKA01696.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF983) COX15-CtaA PF02628.15 KKA01697.1 - 3.9e-113 377.8 1.4 4.7e-113 377.5 1.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein UbiA PF01040.18 KKA01697.1 - 0.05 12.9 0.0 0.05 12.9 0.0 2.6 2 1 0 3 3 3 0 UbiA prenyltransferase family Asp_protease PF09668.10 KKA01698.1 - 2.5e-36 124.2 0.0 4e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KKA01698.1 - 3.7e-11 43.4 0.0 7.7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 KKA01698.1 - 3.9e-07 29.8 0.0 6.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease_2 PF13650.6 KKA01698.1 - 1.1e-06 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KKA01698.1 - 5.2e-05 23.0 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KKA01698.1 - 0.00013 22.3 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease tRNA-synt_1f PF01921.18 KKA01698.1 - 0.0049 15.8 0.6 0.065 12.1 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) Peptidase_A2B PF12384.8 KKA01698.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase DUF3369 PF11849.8 KKA01699.1 - 0.38 10.9 4.3 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) TBP PF00352.21 KKA01700.1 - 6.7e-68 224.7 0.4 6.4e-33 112.6 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KKA01700.1 - 1.8e-06 28.0 0.1 0.069 13.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KKA01700.1 - 0.057 13.2 0.2 0.61 9.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Cyclin_C_2 PF16899.5 KKA01701.1 - 0.071 13.5 0.3 0.31 11.4 0.0 2.3 2 0 0 2 2 2 0 Cyclin C-terminal domain PAP2_3 PF14378.6 KKA01702.1 - 2e-13 50.5 13.9 1.4e-09 38.0 3.3 2.4 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 KKA01702.1 - 0.00025 20.8 3.8 0.00025 20.8 3.8 2.9 2 2 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KKA01702.1 - 0.022 15.3 2.1 0.022 15.3 2.1 3.0 4 1 1 5 5 5 0 PAP2 superfamily C-terminal RcpB PF16971.5 KKA01702.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit Metallophos PF00149.28 KKA01703.1 - 1.2e-31 110.9 0.8 1.7e-31 110.3 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pet100 PF09803.9 KKA01706.1 - 1.2e-06 29.0 0.4 2.5e-06 27.9 0.1 1.7 1 1 1 2 2 2 1 Pet100 Transthyretin PF00576.21 KKA01708.1 - 2.6e-27 95.7 0.1 2.9e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF4049 PF13258.6 KKA01708.1 - 0.012 14.7 0.3 0.012 14.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) PKD_3 PF16820.5 KKA01708.1 - 0.029 14.1 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 PKD-like domain HEPN_AbiV PF18728.1 KKA01708.1 - 0.091 12.9 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 AbiV DDE_1 PF03184.19 KKA01709.1 - 2.6e-48 164.0 5.2 6e-48 162.8 5.2 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KKA01709.1 - 2.3e-11 43.6 0.9 7.7e-11 41.9 0.9 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 KKA01709.1 - 4.2e-06 26.4 0.3 1.2e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 KKA01709.1 - 0.16 12.6 0.1 0.47 11.1 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DDT PF02791.17 KKA01710.1 - 0.14 12.5 1.4 0.4 11.0 0.3 2.3 2 0 0 2 2 2 0 DDT domain CBFD_NFYB_HMF PF00808.23 KKA01711.1 - 0.0023 18.2 0.3 0.0041 17.4 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone THEG4 PF15834.5 KKA01712.1 - 3.8 7.4 7.7 0.78 9.7 2.1 2.5 3 0 0 3 3 3 0 Testis highly expressed protein 4 DUF4809 PF16067.5 KKA01712.1 - 6.5 6.9 7.2 5.3 7.2 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4809) DUF846 PF05832.12 KKA01713.1 - 4e-28 98.2 14.5 5.4e-28 97.8 14.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Serinc PF03348.15 KKA01715.1 - 8.8e-109 364.3 13.3 1e-108 364.1 13.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Rad51 PF08423.11 KKA01716.1 - 7.7e-107 356.3 0.0 1.2e-106 355.7 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KKA01716.1 - 6.1e-12 45.6 0.0 8.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KKA01716.1 - 5.2e-07 29.4 0.0 7.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KKA01716.1 - 2.3e-06 28.1 0.3 6.4e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KKA01716.1 - 1.3e-05 24.7 0.2 4e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.15 KKA01716.1 - 0.021 14.5 0.4 0.049 13.4 0.4 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PX PF00787.24 KKA01716.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 PX domain E1_dh PF00676.20 KKA01717.1 - 1.4e-120 401.8 0.1 1.8e-120 401.5 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component KRTAP7 PF15034.6 KKA01717.1 - 0.00077 20.4 3.4 0.016 16.2 0.1 3.0 2 1 0 2 2 2 1 KRTAP type 7 family DXP_synthase_N PF13292.6 KKA01717.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KKA01717.1 - 0.023 14.5 0.2 0.052 13.3 0.2 1.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Methyltransf_25 PF13649.6 KKA01718.1 - 1.2e-09 38.8 0.0 3.6e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKA01718.1 - 1.8e-08 34.3 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA01718.1 - 1.8e-08 35.0 0.0 1e-07 32.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA01718.1 - 1.1e-07 32.4 0.0 9.1e-07 29.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA01718.1 - 0.00022 21.1 0.0 0.00056 19.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKA01718.1 - 0.00041 19.7 0.0 0.0013 18.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KKA01718.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KKA01718.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KKA01718.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glutaredoxin PF00462.24 KKA01719.1 - 6.9e-19 67.8 0.0 8.5e-18 64.3 0.0 2.7 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 KKA01719.1 - 9.3e-10 38.4 0.1 2.1e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KKA01719.1 - 0.023 14.1 0.9 0.028 13.8 0.9 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KKA01719.1 - 0.064 13.6 0.2 1.3 9.4 0.1 2.7 2 1 1 3 3 3 0 Thioredoxin-like Sec63 PF02889.16 KKA01720.1 - 4.2e-53 180.1 5.3 4.2e-53 180.1 5.3 2.7 5 0 0 5 5 5 1 Sec63 Brl domain DEAD PF00270.29 KKA01720.1 - 3.8e-30 104.9 0.9 1.6e-29 102.9 0.2 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KKA01720.1 - 8.6e-12 45.4 0.1 8.6e-12 45.4 0.1 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKA01720.1 - 6.4e-10 39.4 1.1 2.5e-08 34.2 0.1 3.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 KKA01720.1 - 4.8e-07 30.0 5.9 9.5e-07 29.0 0.2 4.4 3 0 0 3 3 3 1 N-terminal helicase PWI domain AAA_22 PF13401.6 KKA01720.1 - 0.012 15.9 1.0 0.12 12.7 0.2 3.0 2 1 0 2 2 2 0 AAA domain MutS_V PF00488.21 KKA01721.1 - 4.3e-49 167.1 0.1 9.8e-49 165.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKA01721.1 - 2.2e-30 106.3 0.9 2.2e-30 106.3 0.9 2.4 2 2 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KKA01721.1 - 3.2e-27 95.0 0.0 9.1e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KKA01721.1 - 8.3e-11 42.1 1.6 8.3e-11 42.1 1.6 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KKA01721.1 - 9.1e-07 29.2 0.2 9.1e-07 29.2 0.2 3.0 3 0 0 3 3 3 1 MutS domain II AAA_29 PF13555.6 KKA01721.1 - 0.004 16.9 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KKA01721.1 - 0.011 15.6 0.4 0.077 12.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4196 PF13846.6 KKA01721.1 - 0.019 15.2 9.0 0.047 13.9 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) AAA_30 PF13604.6 KKA01721.1 - 0.041 13.6 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKA01721.1 - 0.086 13.3 0.1 0.086 13.3 0.1 4.5 2 1 0 3 3 1 0 AAA domain ABC_tran PF00005.27 KKA01721.1 - 0.094 13.2 3.1 0.15 12.6 0.2 2.8 2 0 0 2 2 2 0 ABC transporter DUF4375 PF14300.6 KKA01721.1 - 2.6 8.3 9.1 2.2 8.6 0.7 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4375) PolyA_pol PF01743.20 KKA01723.1 - 3e-21 76.2 0.3 3.4e-20 72.8 0.3 2.5 1 1 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 KKA01723.1 - 0.059 13.4 1.3 0.2 11.6 0.1 2.3 1 1 1 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative DapB_N PF01113.20 KKA01723.1 - 0.086 13.0 0.1 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Mem_trans PF03547.18 KKA01724.1 - 4.2 5.7 5.9 7.3 4.9 5.9 1.3 1 0 0 1 1 1 0 Membrane transport protein Asp5 PF17000.5 KKA01725.1 - 0.064 13.4 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 Nop16 PF09420.10 KKA01726.1 - 3.8e-59 200.2 18.7 7.6e-59 199.3 18.7 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 LigB PF02900.18 KKA01727.1 - 8.9e-09 34.8 0.1 6.8e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ribosomal_L18_c PF14204.6 KKA01727.1 - 3.6 8.6 7.2 2.4 9.1 1.2 3.0 2 2 1 3 3 3 0 Ribosomal L18 C-terminal region EF-hand_4 PF12763.7 KKA01728.1 - 8.6e-28 96.3 0.0 1.2e-14 54.1 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KKA01728.1 - 1.4e-17 63.8 150.8 0.00044 20.6 32.4 7.2 2 2 2 4 4 4 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 KKA01728.1 - 3.6e-06 26.1 0.3 0.004 16.6 0.0 3.8 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 KKA01728.1 - 4.3e-05 23.9 0.1 0.0071 16.8 0.1 3.3 2 0 0 2 2 2 1 EF-hand domain pair E3_binding PF02817.17 KKA01728.1 - 0.00098 19.4 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain EF-hand_6 PF13405.6 KKA01728.1 - 0.0024 17.7 0.2 2.5 8.2 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KKA01728.1 - 0.031 14.1 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair Bac_rhamnosid_C PF17390.2 KKA01728.1 - 0.039 13.8 2.8 43 4.0 0.1 3.9 1 1 0 3 3 3 0 Bacterial alpha-L-rhamnosidase C-terminal domain Gti1_Pac2 PF09729.9 KKA01729.1 - 2.5e-17 63.6 6.1 3.2e-05 24.1 0.1 4.3 3 2 1 4 4 4 4 Gti1/Pac2 family bZIP_2 PF07716.15 KKA01730.1 - 1.7e-10 40.8 10.2 2.8e-10 40.1 10.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKA01730.1 - 1e-08 35.1 9.0 2.3e-08 34.0 9.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 KKA01730.1 - 0.0048 16.7 5.6 0.014 15.3 5.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.17 KKA01730.1 - 0.036 14.6 6.6 0.078 13.5 6.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Chibby PF14645.6 KKA01730.1 - 0.17 12.3 6.4 0.58 10.6 5.5 2.1 2 1 0 2 2 2 0 Chibby family Oxysterol_BP PF01237.18 KKA01731.1 - 5.7e-129 430.2 2.5 1.1e-128 429.2 2.5 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 KKA01731.1 - 2.2e-07 31.0 0.4 0.00068 19.9 0.5 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KKA01731.1 - 2.3e-07 31.0 1.7 8.1e-05 22.8 0.1 2.8 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 KKA01731.1 - 5.5e-07 30.1 0.1 2.5e-06 28.0 0.1 2.3 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 KKA01731.1 - 3.8e-06 27.4 0.2 0.00059 20.4 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKA01731.1 - 0.0002 21.8 0.4 0.004 17.7 0.6 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA01731.1 - 0.00026 21.2 0.1 0.06 13.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KKA01731.1 - 0.00066 20.0 0.2 0.0039 17.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.6 KKA01731.1 - 0.00074 19.9 0.1 0.00074 19.9 0.1 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain SlyX PF04102.12 KKA01731.1 - 6.9 7.4 6.0 14 6.4 2.9 2.9 2 1 0 2 2 2 0 SlyX His_Phos_1 PF00300.22 KKA01732.1 - 1.4e-28 100.0 0.0 1.3e-14 54.3 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Arginosuc_synth PF00764.19 KKA01733.1 - 1.3e-149 498.7 0.0 1.5e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KKA01733.1 - 6.8e-05 22.5 0.1 0.0001 21.9 0.1 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KKA01733.1 - 0.0023 16.8 0.1 0.004 16.0 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 KKA01733.1 - 0.049 13.3 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase Sdh5 PF03937.16 KKA01734.1 - 2e-21 75.7 0.1 1.5e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase LBP_M PF17385.2 KKA01734.1 - 0.088 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain YicC_N PF03755.13 KKA01734.1 - 0.1 13.0 0.1 0.35 11.3 0.0 1.7 1 1 0 1 1 1 0 YicC-like family, N-terminal region MTCP1 PF08991.10 KKA01735.1 - 0.026 14.7 0.4 6.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 KKA01735.1 - 0.05 13.6 0.2 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Phage_G PF02306.15 KKA01735.1 - 0.066 12.9 0.0 0.22 11.3 0.0 1.7 1 1 1 2 2 2 0 Major spike protein (G protein) Pkinase PF00069.25 KKA01736.1 - 4.2e-63 213.2 0.2 8.7e-63 212.1 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01736.1 - 2.7e-38 131.7 0.0 5.6e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MIR PF02815.19 KKA01736.1 - 0.22 11.4 2.7 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 MIR domain SUN PF03856.13 KKA01737.1 - 2e-90 302.5 13.1 2e-90 302.5 13.1 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) AF-4 PF05110.13 KKA01737.1 - 0.036 12.2 12.9 0.047 11.8 12.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4592 PF15262.6 KKA01737.1 - 0.14 12.8 8.8 0.27 11.9 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Macoilin PF09726.9 KKA01737.1 - 0.17 10.4 8.9 0.22 10.0 8.9 1.0 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KKA01737.1 - 0.76 8.0 13.5 1.2 7.3 13.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-MYND PF01753.18 KKA01737.1 - 0.77 9.9 5.2 2 8.6 5.2 1.6 1 0 0 1 1 1 0 MYND finger Scramblase PF03803.15 KKA01738.1 - 5.5e-42 143.5 0.0 7.9e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Scramblase DisA_N PF02457.16 KKA01739.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Proteasome PF00227.26 KKA01740.1 - 3.6e-31 108.1 0.7 9e-20 71.0 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit HA2 PF04408.23 KKA01741.1 - 6.8e-17 61.7 0.2 3.2e-16 59.6 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKA01741.1 - 3.4e-13 49.9 0.1 3.4e-13 49.9 0.1 3.7 4 1 1 5 5 5 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA01741.1 - 5.8e-13 49.0 1.9 7.6e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KKA01741.1 - 4.2e-09 36.7 0.1 1.2e-08 35.2 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KKA01741.1 - 5.9e-05 23.4 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKA01741.1 - 0.00016 21.5 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KKA01741.1 - 0.00023 21.2 0.4 0.00023 21.2 0.4 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KKA01741.1 - 0.0016 18.8 0.0 0.005 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKA01741.1 - 0.0023 17.0 1.3 0.0035 16.4 0.1 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein LRRC37AB_C PF14914.6 KKA01741.1 - 0.0083 16.0 1.8 0.033 14.1 1.8 2.0 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Flavi_DEAD PF07652.14 KKA01741.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 KKA01741.1 - 0.031 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein DUF1400 PF07176.11 KKA01741.1 - 0.047 14.0 1.7 6.4 7.1 0.1 2.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Helicase_RecD PF05127.14 KKA01741.1 - 0.077 12.8 0.3 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 Helicase AAA_25 PF13481.6 KKA01741.1 - 0.14 11.7 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 KKA01741.1 - 5.1 6.0 15.0 0.25 10.3 0.3 3.0 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region Amino_oxidase PF01593.24 KKA01742.1 - 2.8e-11 43.4 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKA01742.1 - 2.5e-08 34.0 0.0 5.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKA01742.1 - 1.7e-05 24.6 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKA01742.1 - 0.0066 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Peptidase_M41 PF01434.18 KKA01743.1 - 1e-66 224.5 0.0 1.6e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KKA01743.1 - 2.6e-42 144.4 0.0 9e-42 142.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA01743.1 - 2.5e-12 46.4 0.1 7.2e-12 44.9 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKA01743.1 - 0.00015 22.2 0.1 0.0058 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KKA01743.1 - 0.00037 19.8 0.0 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KKA01743.1 - 0.00067 19.4 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKA01743.1 - 0.00074 19.8 0.4 0.052 13.8 0.0 3.0 1 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KKA01743.1 - 0.0016 18.6 0.0 0.025 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKA01743.1 - 0.0018 18.3 0.7 0.01 15.8 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KKA01743.1 - 0.016 15.0 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KKA01743.1 - 0.023 14.9 0.0 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KKA01743.1 - 0.026 15.0 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKA01743.1 - 0.056 14.0 0.0 0.36 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKA01743.1 - 0.18 11.2 0.1 0.39 10.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GCR1_C PF12550.8 KKA01744.1 - 5e-06 26.7 0.9 5e-06 26.7 0.9 4.3 4 1 0 4 4 4 1 Transcriptional activator of glycolytic enzymes DCA16 PF15349.6 KKA01744.1 - 0.081 12.5 1.9 0.22 11.1 1.9 1.7 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 LSM14 PF12701.7 KKA01745.1 - 1.7e-06 28.0 0.5 6.1e-06 26.3 0.5 1.9 1 1 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KKA01745.1 - 3.2e-05 24.0 0.2 0.00011 22.3 0.0 2.0 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF1154 PF06631.11 KKA01745.1 - 0.0013 18.7 6.2 0.0022 18.0 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1154) LSM PF01423.22 KKA01745.1 - 0.028 14.1 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 LSM domain Hid1 PF12722.7 KKA01745.1 - 0.062 11.4 8.6 0.069 11.3 8.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.6 KKA01745.1 - 0.065 13.4 5.5 0.085 13.0 5.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GET2 PF08690.10 KKA01745.1 - 0.079 12.6 3.7 0.092 12.4 3.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 AAA_11 PF13086.6 KKA01745.1 - 0.19 11.5 3.7 0.22 11.2 3.7 1.2 1 0 0 1 1 1 0 AAA domain PI3K_1B_p101 PF10486.9 KKA01745.1 - 0.2 9.4 5.7 0.22 9.3 5.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 KKA01745.1 - 0.27 10.4 18.8 0.32 10.1 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 KKA01745.1 - 0.29 9.9 8.3 0.32 9.7 8.3 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 KKA01745.1 - 0.37 10.0 7.6 0.51 9.5 7.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Folate_carrier PF01770.18 KKA01745.1 - 0.63 8.7 1.0 0.77 8.4 1.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier CDC45 PF02724.14 KKA01745.1 - 0.65 8.2 19.0 0.75 8.0 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KKA01745.1 - 0.94 7.6 23.5 1.2 7.3 23.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 KKA01745.1 - 1 8.3 4.7 1.3 8.0 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mem_trans PF03547.18 KKA01745.1 - 1 7.6 4.2 1.2 7.4 4.2 1.1 1 0 0 1 1 1 0 Membrane transport protein RR_TM4-6 PF06459.12 KKA01745.1 - 1.1 9.0 17.8 1.6 8.5 17.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2315 PF10231.9 KKA01745.1 - 1.7 8.8 12.8 2.6 8.1 12.8 1.3 1 0 0 1 1 1 0 Apoptogenic protein 1 PA26 PF04636.13 KKA01745.1 - 1.9 7.3 6.1 2.2 7.1 6.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2151 PF10221.9 KKA01745.1 - 2.1 6.8 10.7 2.7 6.5 10.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Utp14 PF04615.13 KKA01745.1 - 2.8 6.4 24.7 3.6 6.1 24.7 1.0 1 0 0 1 1 1 0 Utp14 protein Sporozoite_P67 PF05642.11 KKA01745.1 - 2.9 5.9 7.7 3.7 5.5 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GREB1 PF15782.5 KKA01745.1 - 8.6 3.3 6.1 9.7 3.2 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Merozoite_SPAM PF07133.11 KKA01745.1 - 9.2 6.2 34.7 15 5.5 34.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PDDEXK_6 PF04720.12 KKA01745.1 - 9.3 6.1 13.3 13 5.6 13.3 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Mannosyl_trans3 PF11051.8 KKA01746.1 - 1e-72 244.8 0.3 1e-72 244.8 0.3 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 KKA01747.1 - 7.6e-68 228.8 0.8 1.2e-67 228.2 0.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nup54 PF13874.6 KKA01748.1 - 0.02 15.0 0.7 0.037 14.1 0.7 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Med26 PF08711.11 KKA01749.1 - 6.5e-06 26.1 0.8 3.1e-05 23.9 0.2 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF1993 PF09351.10 KKA01750.1 - 0.19 11.8 3.8 0.85 9.7 3.1 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF501 PF04417.12 KKA01750.1 - 0.2 11.4 3.4 0.11 12.3 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF501) APG6_N PF17675.1 KKA01750.1 - 1.5 9.3 30.8 1.8 9.1 14.3 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region LIM PF00412.22 KKA01752.1 - 1.3e-11 44.5 25.2 2.2e-08 34.2 9.0 2.5 2 0 0 2 2 2 2 LIM domain TNFR_c6 PF00020.18 KKA01752.1 - 9.9 6.7 12.1 0.57 10.6 1.2 3.5 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region Patatin PF01734.22 KKA01754.1 - 1.3e-17 64.7 0.0 2.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase dCache_3 PF14827.6 KKA01754.1 - 0.083 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Helicase_C PF00271.31 KKA01755.1 - 5.9e-13 49.1 2.2 2.1e-12 47.4 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.23 KKA01755.1 - 6.5e-11 42.5 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KKA01755.1 - 3.3e-05 23.7 2.3 3.3e-05 23.7 2.3 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2039 PF10217.9 KKA01755.1 - 6.4 7.2 7.9 17 5.8 0.6 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Peptidase_M48 PF01435.18 KKA01756.1 - 1.2e-22 80.7 0.0 2.4e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Kin17_mid PF10357.9 KKA01757.1 - 1.3e-05 25.1 4.5 2.2e-05 24.4 4.5 1.6 1 1 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KKA01757.1 - 0.00024 21.3 1.5 0.00061 20.0 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KKA01757.1 - 0.00052 19.7 0.2 0.0014 18.4 0.2 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 KKA01757.1 - 0.0023 18.3 0.3 0.0049 17.2 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKA01757.1 - 0.0093 16.3 1.4 0.0093 16.3 1.4 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) OSCP PF00213.18 KKA01757.1 - 0.041 14.0 1.3 0.082 13.0 1.3 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit zf-C2H2_4 PF13894.6 KKA01757.1 - 0.12 13.2 0.2 0.35 11.8 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger adh_short_C2 PF13561.6 KKA01758.1 - 6.3e-49 166.6 0.0 7.4e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKA01758.1 - 1e-35 123.0 0.0 1.3e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKA01758.1 - 7.7e-07 29.2 0.1 4.9e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKA01758.1 - 0.0059 15.8 0.1 0.0095 15.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KKA01758.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KKA01758.1 - 0.046 13.1 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Vta1 PF04652.16 KKA01758.1 - 0.16 12.0 1.5 0.21 11.5 0.8 1.7 2 1 0 2 2 2 0 Vta1 like Herpes_capsid PF06112.11 KKA01759.1 - 2.3 8.3 6.9 2.7 8.0 0.4 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Flocculin PF00624.18 KKA01760.1 - 7.7e-05 22.9 11.2 7.7e-05 22.9 11.2 9.5 5 3 2 7 7 7 1 Flocculin repeat Myb_DNA-bind_4 PF13837.6 KKA01761.1 - 0.00093 19.5 0.1 0.0017 18.7 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Lectin_leg-like PF03388.13 KKA01761.1 - 0.0021 17.4 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 Legume-like lectin family Myb_DNA-bind_3 PF12776.7 KKA01761.1 - 0.0026 18.7 1.0 0.0056 17.6 0.1 2.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1854 PF08909.11 KKA01762.1 - 0.052 13.4 1.6 0.2 11.4 1.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) UPF0184 PF03670.13 KKA01762.1 - 0.069 13.6 1.1 0.19 12.1 1.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Asp-B-Hydro_N PF05279.11 KKA01762.1 - 0.31 11.1 5.6 0.48 10.4 5.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_ab PF00006.25 KKA01763.1 - 6.6e-65 218.7 0.0 9.6e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKA01763.1 - 2.6e-14 53.5 1.2 5.2e-14 52.5 1.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_transf_20 PF00982.21 KKA01764.1 - 9.6e-198 657.6 0.0 1.1e-197 657.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KKA01764.1 - 0.00011 21.8 0.6 0.018 14.6 0.1 3.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKA01764.1 - 0.00076 19.9 0.0 0.0024 18.3 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KKA01764.1 - 0.042 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Tau95 PF09734.9 KKA01765.1 - 4.6e-27 95.5 1.2 4.6e-27 95.5 1.2 2.7 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KKA01765.1 - 1e-11 45.1 1.0 7.3e-07 29.4 0.3 2.9 1 1 1 2 2 2 2 Tau95 Triple barrel domain DUF3381 PF11861.8 KKA01765.1 - 0.55 10.0 23.2 2.8 7.7 15.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Ribosomal_60s PF00428.19 KKA01765.1 - 1.1 9.9 10.9 3.2 8.4 10.9 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop53 PF07767.11 KKA01765.1 - 1.2 8.4 21.4 2.3 7.5 21.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YqfQ PF14181.6 KKA01765.1 - 3.4 7.8 8.6 7.2 6.8 8.6 1.5 1 0 0 1 1 1 0 YqfQ-like protein RNA_pol_3_Rpc31 PF11705.8 KKA01765.1 - 3.6 7.8 27.8 0.18 12.0 19.5 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 KKA01765.1 - 3.9 5.7 17.8 0.13 10.5 11.8 1.5 2 0 0 2 2 2 0 CDC45-like protein GTP_EFTU PF00009.27 KKA01767.1 - 7.5e-54 182.2 0.0 1.2e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKA01767.1 - 6.5e-41 139.1 0.0 1.5e-40 138.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKA01767.1 - 3.1e-14 53.1 1.8 3.1e-14 53.1 1.8 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKA01767.1 - 0.00026 21.0 0.1 0.0066 16.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KKA01767.1 - 0.019 14.9 0.9 0.062 13.2 0.9 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Met_asp_mut_E PF06368.11 KKA01767.1 - 0.035 12.6 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Hat1_N PF10394.9 KKA01768.1 - 3.8e-25 89.0 11.5 2.1e-23 83.3 4.7 3.2 2 2 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KKA01768.1 - 5.9e-05 23.3 0.5 0.00012 22.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KKA01768.1 - 0.0014 18.3 2.5 0.0014 18.3 2.5 2.5 1 1 1 2 2 2 1 MOZ/SAS family SDA1 PF05285.12 KKA01768.1 - 0.089 12.2 13.0 0.15 11.5 13.0 1.3 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 KKA01768.1 - 2.5 8.4 14.3 4.8 7.5 14.3 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 KKA01768.1 - 5.7 6.2 16.9 9.4 5.5 16.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.6 KKA01768.1 - 8.3 6.1 11.2 14 5.4 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-TFIIIC PF12660.7 KKA01769.1 - 1.2e-05 25.2 0.5 3.9e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex GDPD PF03009.17 KKA01769.1 - 0.035 13.8 0.6 0.082 12.6 0.6 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family CBF_beta PF02312.17 KKA01771.1 - 0.0049 16.5 0.2 0.0094 15.6 0.2 1.4 1 0 0 1 1 1 1 Core binding factor beta subunit NUC173 PF08161.12 KKA01772.1 - 4.6e-59 199.5 6.3 8.4e-58 195.4 0.3 4.4 4 1 0 4 4 4 2 NUC173 domain HEAT PF02985.22 KKA01772.1 - 0.0097 16.1 3.3 0.03 14.6 0.2 3.6 3 0 0 3 3 3 1 HEAT repeat MIEAP PF16026.5 KKA01772.1 - 0.3 11.3 2.7 0.4 10.9 0.0 2.7 3 0 0 3 3 3 0 Mitochondria-eating protein vATP-synt_E PF01991.18 KKA01774.1 - 3.6e-54 183.2 16.0 4.4e-54 182.9 16.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TubC_N PF18563.1 KKA01774.1 - 0.044 13.8 3.2 6.8 6.8 1.6 3.3 2 1 0 2 2 2 0 TubC N-terminal docking domain DUF2985 PF11204.8 KKA01774.1 - 0.19 11.9 0.2 0.45 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) YfhO PF09586.10 KKA01774.1 - 1.5 6.9 8.1 1.9 6.6 8.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO AAA_11 PF13086.6 KKA01774.1 - 1.7 8.4 9.1 2.3 7.9 9.1 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 KKA01775.1 - 1e-29 104.0 0.7 1e-29 104.0 0.7 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain NFACT-C PF11923.8 KKA01776.1 - 4.4e-19 68.4 0.1 4.4e-19 68.4 0.1 4.3 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 KKA01776.1 - 1e-17 64.1 1.3 1e-17 64.1 1.3 3.3 2 1 1 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KKA01776.1 - 6.3e-09 36.5 0.1 3.5e-08 34.1 0.1 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain SLC12 PF03522.15 KKA01776.1 - 0.00034 19.8 7.5 0.00034 19.8 7.5 3.0 3 1 0 3 3 3 1 Solute carrier family 12 DUF2024 PF09630.10 KKA01776.1 - 0.056 13.3 0.3 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) DNApol_Exo PF18136.1 KKA01777.1 - 2.4e-78 263.1 13.8 7.2e-52 176.3 0.5 3.6 3 0 0 3 3 3 3 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KKA01777.1 - 1.6e-47 162.4 0.3 8.5e-47 160.0 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase family A Peptidase_M3_N PF08439.10 KKA01778.1 - 0.023 15.0 0.5 0.25 11.6 0.0 2.6 2 0 0 2 2 2 0 Oligopeptidase F HEPN_Apea PF18739.1 KKA01778.1 - 0.21 12.0 2.6 0.92 10.0 0.8 2.5 2 0 0 2 2 2 0 Apea-like HEPN Fungal_trans_2 PF11951.8 KKA01779.1 - 3.9e-11 42.4 6.6 2.6e-10 39.7 4.5 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain TPP_enzyme_N PF02776.18 KKA01780.1 - 1.9e-21 76.4 0.0 3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKA01780.1 - 2.7e-14 53.2 0.0 5.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKA01780.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CompInhib_SCIN PF11546.8 KKA01780.1 - 0.0031 17.5 0.2 0.0082 16.2 0.2 1.7 1 0 0 1 1 1 1 Staphylococcal complement inhibitor SCIN Oxidored_nitro PF00148.19 KKA01780.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase WW PF00397.26 KKA01781.1 - 1.4e-08 34.6 1.1 1.4e-08 34.6 1.1 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 KKA01781.1 - 0.0012 19.0 3.1 0.0018 18.4 3.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) WW PF00397.26 KKA01782.1 - 1.2e-06 28.5 2.9 3.1e-06 27.2 2.9 1.8 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KKA01782.1 - 6.9e-05 23.0 12.7 6.9e-05 23.0 12.7 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 KKA01782.1 - 0.085 13.5 9.1 0.14 12.8 9.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioredoxin_4 PF13462.6 KKA01783.1 - 1.1e-08 35.4 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KKA01784.1 - 1.5e-11 44.8 0.0 2.2e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KKA01784.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_2 PF07724.14 KKA01785.1 - 1e-47 162.4 0.2 2.9e-44 151.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKA01785.1 - 3.6e-28 97.5 1.3 3.6e-28 97.5 1.3 2.9 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 KKA01785.1 - 1.1e-25 90.6 0.2 2.3e-13 50.7 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKA01785.1 - 4.5e-20 71.5 0.2 4.5e-20 71.5 0.2 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKA01785.1 - 3.4e-15 56.3 0.1 2.4e-10 40.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KKA01785.1 - 1.1e-14 54.3 2.4 1.7e-08 34.5 0.0 3.2 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 KKA01785.1 - 2e-14 53.7 0.1 7.1e-09 35.6 0.0 2.9 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 KKA01785.1 - 1.1e-11 45.4 8.3 6.3e-05 23.4 0.1 5.3 5 1 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KKA01785.1 - 3.6e-09 37.0 2.4 0.0026 18.0 0.3 4.3 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 KKA01785.1 - 1.3e-08 34.5 0.4 7.5e-05 22.2 0.3 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 KKA01785.1 - 3.4e-08 33.6 0.0 0.0014 18.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KKA01785.1 - 6.8e-07 28.9 0.1 0.11 11.8 0.0 3.6 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KKA01785.1 - 5.6e-06 25.8 4.0 0.092 11.9 0.0 3.5 2 1 1 3 3 3 2 TIP49 P-loop domain Zeta_toxin PF06414.12 KKA01785.1 - 3.3e-05 23.3 0.1 0.011 15.0 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_7 PF12775.7 KKA01785.1 - 4.2e-05 23.1 0.1 0.35 10.3 0.1 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KKA01785.1 - 6.9e-05 22.7 0.2 0.29 10.9 0.2 3.0 2 1 0 2 2 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KKA01785.1 - 0.00018 21.4 0.2 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KKA01785.1 - 0.00019 21.2 0.0 0.056 13.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KKA01785.1 - 0.00041 20.3 0.0 0.91 9.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_3 PF07726.11 KKA01785.1 - 0.00048 20.0 0.0 0.026 14.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KKA01785.1 - 0.00049 20.6 2.6 0.42 11.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 KKA01785.1 - 0.00055 20.5 5.0 0.55 10.8 0.1 3.9 4 1 0 4 4 2 2 AAA domain RuvB_N PF05496.12 KKA01785.1 - 0.00059 19.6 3.5 1.9 8.2 0.1 3.8 3 1 1 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KKA01785.1 - 0.00085 19.4 0.3 3.2 7.7 0.0 3.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KKA01785.1 - 0.00093 18.9 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain TsaE PF02367.17 KKA01785.1 - 0.0011 18.9 0.2 2.5 8.1 0.0 2.9 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KKA01785.1 - 0.0015 18.1 0.6 3.7 7.1 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KKA01785.1 - 0.0015 18.3 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KKA01785.1 - 0.0023 17.9 10.8 0.97 9.3 0.1 4.9 3 3 2 5 5 5 2 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 KKA01785.1 - 0.003 17.3 0.0 0.24 11.2 0.0 3.2 3 1 0 3 3 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KKA01785.1 - 0.0033 16.6 0.2 0.91 8.6 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Torsin PF06309.11 KKA01785.1 - 0.0038 17.3 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Torsin NTPase_1 PF03266.15 KKA01785.1 - 0.0043 17.0 0.5 0.14 12.0 0.1 2.9 3 0 0 3 3 3 1 NTPase AAA_19 PF13245.6 KKA01785.1 - 0.015 15.7 2.5 5.6 7.3 1.1 3.8 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKA01785.1 - 0.018 15.4 0.0 7.4 7.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KKA01785.1 - 0.027 14.3 3.8 7.1 6.3 0.1 4.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PIF1 PF05970.14 KKA01785.1 - 0.027 13.6 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase PEPCK_ATP PF01293.20 KKA01785.1 - 0.028 13.1 0.0 0.055 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase CbiA PF01656.23 KKA01785.1 - 0.043 13.9 1.8 1.5 8.9 0.0 3.2 3 2 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KKA01785.1 - 0.046 12.9 0.0 2.6 7.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 KKA01785.1 - 0.055 13.7 0.1 13 6.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KKA01785.1 - 0.12 12.1 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KKA01785.1 - 0.19 11.9 0.7 7.6 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Nup54 PF13874.6 KKA01785.1 - 0.3 11.2 6.6 1.6 8.8 6.6 2.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 AAA_28 PF13521.6 KKA01785.1 - 0.31 11.3 2.6 25 5.1 0.0 3.5 3 1 1 4 4 2 0 AAA domain Rootletin PF15035.6 KKA01785.1 - 0.32 11.0 11.7 0.73 9.8 7.1 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Creatinase_N_2 PF16189.5 KKA01786.1 - 1.2e-39 136.0 2.2 2e-39 135.3 0.5 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KKA01786.1 - 9.8e-39 133.2 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KKA01786.1 - 2.7e-20 72.2 0.4 7.4e-20 70.8 0.4 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KKA01786.1 - 1.2e-09 38.9 0.0 4.3e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Phosphodiest PF01663.22 KKA01787.1 - 1.4e-11 44.6 3.2 3e-11 43.5 2.5 1.6 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKA01787.1 - 0.027 13.8 0.2 0.044 13.2 0.2 1.3 1 0 0 1 1 1 0 Sulfatase KH_1 PF00013.29 KKA01788.1 - 9.6e-12 44.6 2.2 7e-08 32.2 0.1 3.5 3 0 0 3 3 3 2 KH domain CPSF_A PF03178.15 KKA01789.1 - 2.5e-16 59.9 0.5 1.1e-15 57.8 0.5 2.1 1 0 0 1 1 1 1 CPSF A subunit region MMR_HSR1_Xtn PF16897.5 KKA01790.1 - 1.1e-36 125.0 0.0 2.1e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KKA01790.1 - 3.5e-21 75.4 0.1 1.3e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KKA01790.1 - 1.6e-19 69.7 0.1 3.4e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KKA01790.1 - 6.8e-08 32.2 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKA01790.1 - 8.4e-05 22.7 0.3 0.016 15.2 0.6 2.5 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KKA01790.1 - 0.0001 22.2 2.5 0.044 13.7 0.1 3.2 2 1 1 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KKA01790.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 KKA01790.1 - 0.0047 16.4 0.4 0.015 14.7 0.2 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KKA01790.1 - 0.008 15.2 0.2 0.28 10.1 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KKA01790.1 - 0.022 15.0 0.2 2.3 8.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KKA01790.1 - 0.029 14.6 0.0 0.093 13.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BRCT_2 PF16589.5 KKA01791.1 - 1.1e-09 38.5 3.5 1.1e-09 38.5 0.3 2.7 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKA01791.1 - 2.3e-06 27.9 3.2 4.3e-06 27.0 0.1 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 KKA01791.1 - 0.006 16.6 0.1 0.025 14.6 0.1 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Aminotran_5 PF00266.19 KKA01792.1 - 7.8e-07 28.4 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKA01792.1 - 0.0029 16.8 0.3 0.012 14.8 0.1 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KKA01792.1 - 0.088 12.1 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family TIM21 PF08294.11 KKA01793.1 - 1.4e-40 138.5 0.0 1.8e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 PIRT PF15099.6 KKA01793.1 - 0.04 13.5 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Pox_P35 PF03213.14 KKA01793.1 - 0.048 12.9 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein SUR7 PF06687.12 KKA01794.1 - 3.3e-38 131.5 14.1 4.8e-38 130.9 14.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family Suc_Fer-like PF06999.12 KKA01796.1 - 2.6e-30 105.8 0.2 3.5e-30 105.3 0.2 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DnaJ_C PF01556.18 KKA01798.1 - 8.8e-29 100.5 0.2 1.3e-28 99.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKA01798.1 - 8.6e-25 86.6 3.8 8.6e-25 86.6 3.8 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKA01798.1 - 2.7e-11 43.6 21.2 4.9e-11 42.8 21.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_CBB3 PF13442.6 KKA01798.1 - 0.0012 19.1 8.4 0.032 14.6 0.0 2.9 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KKA01798.1 - 0.2 12.8 4.7 0.69 11.1 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c DZR PF12773.7 KKA01798.1 - 0.21 11.7 7.9 0.54 10.3 1.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 KKA01798.1 - 0.23 11.5 8.9 3.7 7.6 2.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 KKA01798.1 - 0.27 11.7 12.1 0.49 10.9 2.3 2.5 1 1 1 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.16 KKA01798.1 - 2 8.8 10.5 27 5.2 2.2 2.6 1 1 1 2 2 2 0 Class III cytochrome C family DUF2318 PF10080.9 KKA01798.1 - 5.2 7.2 9.8 3.9 7.6 5.0 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Myb_DNA-bind_5 PF13873.6 KKA01799.1 - 1.3e-06 28.4 3.2 1.7e-06 28.0 1.8 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KKA01799.1 - 8.9e-05 22.7 1.0 0.00032 20.9 1.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 KKA01799.1 - 0.00081 19.7 1.9 0.0027 18.1 1.9 2.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KKA01799.1 - 0.0012 19.8 4.1 0.0012 19.8 4.1 2.6 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA01799.1 - 0.0085 16.3 1.9 0.016 15.5 0.7 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKA01799.1 - 0.014 15.5 0.5 0.031 14.5 0.5 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain ETF_alpha PF00766.19 KKA01800.1 - 2.1e-29 101.4 1.9 4.2e-29 100.4 1.9 1.5 1 1 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 KKA01800.1 - 1.9e-09 37.7 0.0 3.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PPIP5K2_N PF18086.1 KKA01800.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain TPP_enzyme_N PF02776.18 KKA01801.1 - 3.1e-34 118.0 0.0 5.4e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKA01801.1 - 2.3e-27 95.4 0.0 6.5e-25 87.5 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKA01801.1 - 3.3e-12 46.5 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 KKA01801.1 - 0.17 12.0 0.1 6 7.1 0.0 2.6 2 0 0 2 2 2 0 OCC1 family Abhydrolase_1 PF00561.20 KKA01801.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FGGY_N PF00370.21 KKA01802.1 - 7.9e-40 137.0 0.5 1.2e-39 136.3 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KKA01802.1 - 1.2e-36 126.3 0.0 7.3e-36 123.8 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_S7 PF00949.21 KKA01802.1 - 0.04 13.8 0.2 0.47 10.3 0.0 2.5 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Ribosomal_L7Ae PF01248.26 KKA01803.1 - 3.1e-23 81.3 0.6 5.3e-23 80.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NDK PF00334.19 KKA01805.1 - 1.6e-53 180.3 0.0 1.8e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_M24 PF00557.24 KKA01805.1 - 0.043 13.5 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 Aldo_ket_red PF00248.21 KKA01806.1 - 6.2e-31 107.7 0.0 7.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PC4 PF02229.16 KKA01807.1 - 4.4e-22 77.4 0.1 8.8e-22 76.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF735 PF05246.11 KKA01807.1 - 0.022 14.7 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF735) Sigma_reg_N PF13800.6 KKA01808.1 - 0.0029 17.9 0.2 0.0058 16.9 0.2 1.6 1 0 0 1 1 1 1 Sigma factor regulator N-terminal DUF4492 PF14899.6 KKA01808.1 - 0.11 12.4 1.9 0.32 10.9 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Use1 PF09753.9 KKA01808.1 - 0.53 10.0 9.8 0.4 10.4 0.3 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 HMA PF00403.26 KKA01809.1 - 0.00067 20.1 0.5 0.0029 18.0 0.1 2.3 3 0 0 3 3 3 1 Heavy-metal-associated domain DUF2181 PF10223.9 KKA01809.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) Fer4_4 PF12800.7 KKA01809.1 - 0.36 11.5 0.3 0.36 11.5 0.3 2.1 3 0 0 3 3 3 0 4Fe-4S binding domain CorA PF01544.18 KKA01810.1 - 5.4e-37 127.7 1.2 1.1e-20 74.1 0.0 3.5 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KKA01812.1 - 1.1e-20 74.1 0.4 8.4e-20 71.2 0.4 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01812.1 - 1.7e-08 34.0 0.0 6.6e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Trehalose_recp PF06151.13 KKA01812.1 - 0.049 12.2 0.2 0.082 11.5 0.2 1.2 1 0 0 1 1 1 0 Trehalose receptor Pkinase_fungal PF17667.1 KKA01812.1 - 0.054 12.3 0.2 0.44 9.3 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Rhodanese PF00581.20 KKA01814.1 - 2.2e-14 53.9 0.0 3.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S24 PF00717.23 KKA01815.1 - 7.3e-11 41.9 0.0 9.9e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KKA01815.1 - 4.2e-05 23.3 0.0 0.00096 19.0 0.0 2.1 1 1 0 2 2 2 1 Signal peptidase, peptidase S26 DDR PF08841.10 KKA01815.1 - 0.11 11.5 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TCTP PF00838.17 KKA01817.1 - 7e-71 237.9 0.7 7.8e-71 237.8 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RcbX PF02341.15 KKA01817.1 - 0.093 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 RbcX protein ZnuA PF01297.17 KKA01817.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic adh_short PF00106.25 KKA01818.1 - 7.7e-13 48.3 0.2 3.3e-08 33.2 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKA01818.1 - 2.1e-05 24.2 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PABP PF00658.18 KKA01818.1 - 0.014 15.6 0.3 0.039 14.1 0.3 1.8 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain CUE PF02845.16 KKA01819.1 - 3.2e-11 42.7 0.0 6.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.12 KKA01820.1 - 1.5e-12 47.6 2.3 2.1e-12 47.1 2.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX6B PF02297.17 KKA01820.1 - 0.0053 17.0 0.7 0.0072 16.5 0.7 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 KKA01820.1 - 0.0089 16.2 0.3 0.012 15.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 KKA01820.1 - 0.016 15.2 3.1 0.21 11.6 0.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KKA01820.1 - 0.033 14.3 3.8 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 CHCH domain UPF0203 PF05254.12 KKA01821.1 - 3.4e-15 56.0 3.7 3.4e-15 56.0 3.7 1.6 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0203) UPF0183 PF03676.14 KKA01821.1 - 0.027 13.8 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) COX6B PF02297.17 KKA01821.1 - 0.091 13.0 5.8 4.6 7.6 0.4 1.9 1 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KKA01821.1 - 0.14 12.2 1.9 0.51 10.4 0.2 2.4 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, tRNA-synt_1g PF09334.11 KKA01822.1 - 3.2e-83 279.7 5.4 4.1e-83 279.3 5.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKA01822.1 - 2.3e-16 59.2 0.3 1e-10 40.5 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KKA01822.1 - 2.9e-07 30.2 1.3 0.0024 17.2 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KKA01822.1 - 0.0053 16.7 0.1 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Yip1 PF04893.17 KKA01823.1 - 1.2e-06 28.4 9.2 3.5e-06 26.9 9.2 1.9 1 1 0 1 1 1 1 Yip1 domain MMR_HSR1_Xtn PF16897.5 KKA01824.1 - 2.6e-35 120.6 0.3 4.9e-35 119.7 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KKA01824.1 - 2.7e-18 65.7 0.0 2.2e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 KKA01824.1 - 5e-18 65.2 0.1 1.2e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKA01824.1 - 2e-09 37.2 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKA01824.1 - 9.4e-06 25.8 0.2 0.014 15.5 0.0 2.6 2 0 0 2 2 2 2 Dynamin family YchF-GTPase_C PF06071.13 KKA01824.1 - 0.099 12.8 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF933) MeaB PF03308.16 KKA01824.1 - 0.099 11.6 0.1 0.73 8.8 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mucin_bdg PF03272.13 KKA01824.1 - 0.1 12.7 0.3 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module ABC_tran PF00005.27 KKA01824.1 - 0.11 13.0 0.5 0.27 11.8 0.5 2.0 1 1 0 1 1 1 0 ABC transporter SH3_2 PF07653.17 KKA01826.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKA01826.1 - 0.019 14.8 0.0 0.06 13.2 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain ADIP PF11559.8 KKA01826.1 - 0.59 10.2 14.6 0.023 14.8 5.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PseudoU_synth_2 PF00849.22 KKA01827.1 - 1.7e-23 83.5 0.4 3e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 RNA pseudouridylate synthase Glyco_hydro_16 PF00722.21 KKA01828.1 - 1.9e-42 144.7 2.7 1.9e-42 144.7 2.7 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PGA_cap PF09587.10 KKA01828.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Apt1 PF10351.9 KKA01828.1 - 4.7 6.0 15.5 6.3 5.5 15.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_Rpb4 PF03874.16 KKA01829.1 - 2.1e-21 76.5 2.2 2.5e-21 76.3 2.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1844 PF08899.11 KKA01829.1 - 0.12 12.6 0.4 0.39 11.1 0.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) PRC2_HTH_1 PF18118.1 KKA01829.1 - 0.32 11.8 2.2 14 6.6 1.6 2.2 1 1 1 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Cpn60_TCP1 PF00118.24 KKA01830.1 - 1.6e-158 528.4 6.2 1.9e-158 528.2 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KKA01831.1 - 4.2e-16 59.1 2.4 1.3e-15 57.5 2.4 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01831.1 - 1.3e-08 34.4 0.4 5.7e-08 32.4 0.4 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KKA01831.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KKA01831.1 - 0.0077 15.6 0.2 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKA01831.1 - 0.052 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like VTC PF09359.10 KKA01832.1 - 1.1e-92 310.4 0.3 1.1e-92 310.4 0.3 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KKA01832.1 - 1.4e-08 35.0 1.6 3e-08 34.0 1.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KKA01832.1 - 3.8e-05 23.8 2.1 3.8e-05 23.8 2.1 2.9 3 1 0 3 3 3 1 SPX domain Baculo_LEF-11 PF06385.12 KKA01832.1 - 0.83 10.2 4.8 0.37 11.3 1.8 2.0 2 0 0 2 2 2 0 Baculovirus LEF-11 protein YlzJ PF14035.6 KKA01833.1 - 0.00027 21.1 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 2 2 YlzJ-like protein Pkinase PF00069.25 KKA01834.1 - 2.2e-68 230.5 0.1 2.2e-68 230.5 0.1 2.9 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01834.1 - 3.9e-37 127.9 1.4 3.9e-37 127.9 1.4 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KKA01834.1 - 9.5e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKA01834.1 - 0.00014 21.3 0.0 0.013 14.9 0.0 2.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKA01834.1 - 0.0049 16.8 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Lung_7-TM_R PF06814.13 KKA01835.1 - 5.3e-73 245.8 24.3 6.7e-73 245.5 24.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor NifU PF01106.17 KKA01836.1 - 2.2e-22 79.0 0.0 4.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 KKA01836.1 - 4.4e-12 45.9 2.1 5.9e-12 45.5 0.2 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal DUF1068 PF06364.12 KKA01836.1 - 0.006 16.5 0.3 0.006 16.5 0.3 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1068) muHD PF10291.9 KKA01836.1 - 0.01 15.3 0.8 0.036 13.5 0.1 2.0 1 1 1 2 2 2 0 Muniscin C-terminal mu homology domain Pro-MCH PF05824.12 KKA01836.1 - 0.19 11.7 2.8 0.62 10.0 0.0 2.8 2 1 1 3 3 3 0 Pro-melanin-concentrating hormone (Pro-MCH) Thioredoxin PF00085.20 KKA01837.1 - 1.1e-24 86.3 0.1 1.6e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKA01837.1 - 8.8e-06 26.1 0.3 2.7e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KKA01837.1 - 7.5e-05 22.2 0.7 0.00015 21.2 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KKA01837.1 - 0.00029 20.7 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 KKA01837.1 - 0.00099 19.0 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKA01837.1 - 0.0015 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KKA01837.1 - 0.0024 18.2 0.1 0.0089 16.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KKA01837.1 - 0.021 14.9 0.3 0.035 14.1 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.6 KKA01837.1 - 0.047 13.4 0.5 0.43 10.2 0.0 2.4 2 1 1 3 3 3 0 Thioredoxin TMEM144 PF07857.12 KKA01837.1 - 0.18 10.7 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Sugar_tr PF00083.24 KKA01838.1 - 1.1e-63 215.7 33.1 1.2e-63 215.5 33.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA01838.1 - 6.2e-10 38.5 29.5 1.1e-09 37.7 25.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3975 PF13126.6 KKA01838.1 - 0.006 17.0 2.9 0.006 17.0 2.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3975) KTI12 PF08433.10 KKA01840.1 - 3.9e-58 197.1 4.0 5.5e-58 196.6 4.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KKA01840.1 - 3.8e-06 27.5 2.6 7.3e-06 26.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 KKA01840.1 - 0.0046 17.2 0.4 0.11 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KKA01840.1 - 0.061 13.7 0.0 0.29 11.5 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KKA01841.1 - 4.3e-10 39.7 0.5 1.7e-09 37.8 0.5 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKA01841.1 - 0.0012 18.8 0.1 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KKA01841.1 - 0.0091 15.5 3.1 0.069 12.7 0.3 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B CNP_C_terminal PF17839.1 KKA01841.1 - 0.18 12.6 0.2 0.18 12.6 0.2 3.1 3 0 0 3 3 3 0 C-terminal domain of cyclic nucleotide phosphodiesterase Mito_carr PF00153.27 KKA01842.1 - 3.5e-59 196.7 7.1 4.1e-19 68.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltransf PF01255.19 KKA01843.1 - 1.9e-60 204.2 0.4 2.6e-60 203.8 0.4 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Lipoprotein_3 PF00938.17 KKA01843.1 - 0.068 13.4 0.5 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Lipoprotein Vma12 PF11712.8 KKA01844.1 - 4.1e-18 65.8 1.5 1e-17 64.5 1.4 1.6 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase IF4E PF01652.18 KKA01845.1 - 3.5e-37 127.6 5.8 5.8e-37 126.9 4.8 1.8 1 1 1 2 2 2 1 Eukaryotic initiation factor 4E DUF1688 PF07958.11 KKA01846.1 - 8e-147 489.3 0.0 9.1e-147 489.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Ribosomal_S10 PF00338.22 KKA01847.1 - 1.5e-16 60.4 0.1 1.9e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e OTU PF02338.19 KKA01849.1 - 7.8e-18 65.2 0.5 7.8e-18 65.2 0.5 3.1 3 2 0 3 3 3 1 OTU-like cysteine protease LMBR1 PF04791.16 KKA01849.1 - 4.9 5.9 12.5 6.9 5.4 12.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Erg28 PF03694.13 KKA01850.1 - 2.5e-41 140.5 1.4 3.2e-41 140.2 1.4 1.1 1 0 0 1 1 1 1 Erg28 like protein TPP_enzyme_N PF02776.18 KKA01851.1 - 1.8e-55 187.2 0.3 1e-53 181.5 0.2 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKA01851.1 - 1.1e-48 164.9 0.1 8.9e-47 158.7 0.1 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKA01851.1 - 5.3e-39 133.1 0.4 1.3e-38 131.8 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KKA01851.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Myosin_head PF00063.21 KKA01852.1 - 5.9e-235 781.6 12.6 8.3e-235 781.1 12.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KKA01852.1 - 1.4e-44 152.0 0.9 4e-44 150.5 0.9 1.9 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 KKA01852.1 - 9.2e-07 28.6 0.1 2.3e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKA01852.1 - 5.7e-05 22.6 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKA01852.1 - 0.0022 17.7 0.0 0.0055 16.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 KKA01852.1 - 0.0046 16.5 0.6 8.6 5.8 0.0 3.6 4 0 0 4 4 4 2 HPr Serine kinase C-terminal domain Abi_C PF14355.6 KKA01852.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.0 1 0 0 1 1 1 0 Abortive infection C-terminus Sigma54_activat PF00158.26 KKA01852.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 KKA01852.1 - 0.061 13.6 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKA01852.1 - 0.1 13.0 0.0 0.54 10.7 0.0 2.3 1 0 0 1 1 1 0 RNA helicase Guanylate_cyc PF00211.20 KKA01852.1 - 0.11 12.1 0.3 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KKA01852.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NID PF07292.13 KKA01852.1 - 0.14 12.8 0.3 0.65 10.7 0.1 2.3 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) NACHT PF05729.12 KKA01852.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain She2p PF11435.8 KKA01853.1 - 4.9e-37 127.6 14.9 1.8e-19 70.3 3.5 2.2 2 0 0 2 2 2 2 RNA binding protein She2p MSA-2c PF12238.8 KKA01853.1 - 0.82 9.6 8.5 2.5 8.1 0.9 2.2 1 1 1 2 2 2 0 Merozoite surface antigen 2c GCR1_C PF12550.8 KKA01854.1 - 1.4e-18 67.0 0.4 2.6e-17 62.9 0.0 3.0 3 1 0 3 3 3 1 Transcriptional activator of glycolytic enzymes BLOC1S3 PF15753.5 KKA01854.1 - 0.089 12.9 2.9 0.37 10.9 0.3 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF5481 PF17578.2 KKA01854.1 - 0.15 12.5 1.9 0.23 11.9 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5481) ABC2_membrane_3 PF12698.7 KKA01854.1 - 0.5 9.4 4.7 0.65 9.0 4.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1722 PF08349.11 KKA01854.1 - 0.66 10.3 5.2 7.2 6.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) SYF2 PF08231.12 KKA01854.1 - 2 8.8 9.1 1.5 9.2 6.1 2.1 1 1 0 2 2 2 0 SYF2 splicing factor Mur_ligase_M PF08245.12 KKA01855.1 - 4.6e-10 39.8 1.7 1.6e-09 38.1 0.4 2.4 2 1 0 2 2 2 1 Mur ligase middle domain CTP_transf_like PF01467.26 KKA01855.1 - 0.071 13.3 1.3 4.5 7.5 1.3 2.4 1 1 0 1 1 1 0 Cytidylyltransferase-like ER PF01133.17 KKA01856.1 - 0.0099 15.9 1.5 0.0099 15.9 1.5 2.3 2 0 0 2 2 2 1 Enhancer of rudimentary Peptidase_M3 PF01432.20 KKA01857.1 - 3.9e-79 267.1 4.7 5.4e-79 266.6 4.7 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KKA01857.1 - 0.075 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like GerD PF17898.1 KKA01857.1 - 0.095 12.7 5.3 0.21 11.6 0.1 2.7 2 0 0 2 2 2 0 Spore germination GerD central core domain Adaptin_N PF01602.20 KKA01858.1 - 1e-58 199.2 30.1 1.3e-58 198.9 30.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKA01858.1 - 5.9e-28 97.9 2.8 5.9e-28 97.9 2.8 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ERAP1_C PF11838.8 KKA01858.1 - 0.053 13.1 0.4 0.88 9.0 0.1 2.9 3 1 0 3 3 3 0 ERAP1-like C-terminal domain Ipi1_N PF12333.8 KKA01858.1 - 0.16 12.6 0.3 0.88 10.2 0.1 2.3 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation L31 PF09784.9 KKA01859.1 - 1.9e-10 41.1 2.8 2.8e-10 40.5 2.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Abhydrolase_1 PF00561.20 KKA01861.1 - 9.4e-19 68.0 0.1 8.6e-10 38.7 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KKA01861.1 - 3.7e-18 64.9 0.1 8.9e-18 63.6 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.16 KKA01861.1 - 6.1e-05 22.9 0.1 0.0078 16.0 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 KKA01861.1 - 6.6e-05 22.7 0.1 0.11 12.1 0.0 2.3 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KKA01861.1 - 0.0011 18.3 0.0 1.1 8.5 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Sdh_cyt PF01127.22 KKA01862.1 - 5.3e-22 78.1 0.3 7e-22 77.7 0.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Snf7 PF03357.21 KKA01864.1 - 1.3e-37 129.1 19.7 1.3e-37 129.1 19.7 1.9 2 0 0 2 2 2 1 Snf7 GAD PF02938.14 KKA01864.1 - 0.35 11.1 4.0 13 6.1 0.1 2.6 1 1 0 2 2 2 0 GAD domain Snapin_Pallidin PF14712.6 KKA01864.1 - 0.67 10.4 15.7 0.32 11.4 9.0 2.7 1 1 1 2 2 2 0 Snapin/Pallidin SNARE PF05739.19 KKA01865.1 - 7.4e-11 41.9 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KKA01865.1 - 0.00029 20.0 0.5 0.00069 18.8 0.5 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KKA01865.1 - 0.0041 16.8 2.6 0.0041 16.8 2.6 2.8 2 1 1 3 3 3 1 Syntaxin DUF2203 PF09969.9 KKA01865.1 - 0.0052 17.5 2.8 3 8.6 0.1 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2203) Syntaxin-18_N PF10496.9 KKA01865.1 - 0.25 11.6 6.2 0.41 10.9 0.9 2.9 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.11 KKA01865.1 - 1.1 9.7 12.2 0.11 12.9 1.1 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 KKA01865.1 - 6.5 6.4 12.3 7.7 6.2 5.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Aminotran_1_2 PF00155.21 KKA01866.1 - 4.3e-75 253.2 0.0 4.9e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FMN_red PF03358.15 KKA01866.1 - 0.084 12.6 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 NADPH-dependent FMN reductase zf-C3HC4_3 PF13920.6 KKA01867.1 - 5.7e-09 35.7 13.7 1e-08 34.9 13.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKA01867.1 - 0.00055 19.7 13.6 0.001 18.9 13.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KKA01867.1 - 7.6 6.4 15.3 18 5.2 15.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gon7 PF08738.10 KKA01868.1 - 3.2e-14 52.9 1.9 5.3e-14 52.2 1.9 1.4 1 1 0 1 1 1 1 Gon7 family MFS_1 PF07690.16 KKA01869.1 - 5.3e-29 101.2 17.7 9.5e-29 100.4 17.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_transf_34 PF05637.12 KKA01870.1 - 8.3e-40 137.0 8.2 3.4e-39 135.0 8.2 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family CdiA_C PF18451.1 KKA01870.1 - 0.016 15.4 2.4 2.1 8.6 0.2 3.7 3 1 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain ATP12 PF07542.11 KKA01871.1 - 2.4e-29 102.0 0.1 5.8e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein SF3A3 PF16837.5 KKA01871.1 - 0.0035 17.8 0.6 0.018 15.6 0.3 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 ATG27 PF09451.10 KKA01872.1 - 1.5e-17 64.3 0.2 2.3e-17 63.7 0.2 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CASP_C PF08172.12 KKA01873.1 - 4e-07 29.6 23.1 0.0005 19.5 21.6 2.5 1 1 0 1 1 1 1 CASP C terminal TMF_DNA_bd PF12329.8 KKA01873.1 - 0.023 14.7 14.5 0.73 9.9 3.4 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PRKG1_interact PF15898.5 KKA01873.1 - 0.14 13.1 13.9 0.15 12.9 5.1 2.8 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KKA01873.1 - 0.29 11.7 8.2 1.7 9.1 2.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 KKA01873.1 - 2.4 8.3 12.1 6 7.0 0.7 3.7 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF3450 PF11932.8 KKA01873.1 - 2.5 7.3 12.7 0.95 8.7 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KKA01873.1 - 8.5 6.4 9.2 8.9 6.4 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SWIRM PF04433.17 KKA01874.1 - 2.1e-22 79.2 0.2 5.6e-22 77.9 0.2 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KKA01874.1 - 0.00049 20.0 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 KKA01874.1 - 0.015 15.6 0.1 0.039 14.2 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KKA01874.1 - 0.064 13.6 2.5 0.16 12.4 0.0 2.9 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain CC190 PF15768.5 KKA01874.1 - 2 8.4 15.3 0.1 12.6 6.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 190 Zip PF02535.22 KKA01876.1 - 3.5e-18 65.9 24.6 1.7e-13 50.5 12.0 3.4 2 2 0 2 2 2 2 ZIP Zinc transporter FAM176 PF14851.6 KKA01876.1 - 0.006 16.2 2.8 0.23 11.1 0.0 2.9 3 0 0 3 3 3 2 FAM176 family CbtA PF09490.10 KKA01876.1 - 0.013 15.3 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF997 PF06196.12 KKA01876.1 - 0.42 10.7 1.9 0.83 9.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF2401 PF10287.9 KKA01878.1 - 9.6e-79 264.2 4.5 9.6e-79 264.2 4.5 1.6 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KKA01878.1 - 1.4e-20 73.4 0.7 4.4e-20 71.9 0.1 2.2 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) STE3 PF02076.15 KKA01879.1 - 9e-67 225.3 24.1 1.1e-66 225.0 24.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_M20 PF01546.28 KKA01880.1 - 1.2e-29 103.6 0.0 3.8e-29 101.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKA01880.1 - 2.8e-11 43.3 0.0 5.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Vac_ImportDeg PF09783.9 KKA01880.1 - 0.0011 18.8 0.1 0.0028 17.5 0.1 1.6 1 0 0 1 1 1 1 Vacuolar import and degradation protein Ebp2 PF05890.12 KKA01881.1 - 7.1e-72 242.2 33.3 7.1e-72 242.2 33.3 2.7 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 Nop14 PF04147.12 KKA01881.1 - 0.14 10.3 52.8 0.0046 15.2 30.4 2.2 2 0 0 2 2 2 0 Nop14-like family polyprenyl_synt PF00348.17 KKA01882.1 - 5.7e-96 320.5 0.1 6.9e-96 320.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 KKA01883.1 - 1.2e-43 149.4 4.3 6.6e-31 107.6 1.8 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01883.1 - 7.8e-30 104.0 2.9 1.4e-23 83.5 0.7 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKA01883.1 - 2.4e-06 27.1 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KKA01883.1 - 0.00029 20.9 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKA01883.1 - 0.0007 19.2 0.1 0.0024 17.5 0.1 1.9 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KKA01883.1 - 0.0024 16.7 0.2 0.0043 15.9 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KKA01883.1 - 0.099 11.6 17.0 0.0062 15.5 3.2 3.8 2 1 1 3 3 3 0 Haspin like kinase domain Ribosomal_L14 PF00238.19 KKA01884.1 - 7.1e-29 100.4 1.7 7.8e-29 100.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 KKA01885.1 - 1e-36 126.7 2.3 1.8e-31 109.5 0.1 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01885.1 - 2.4e-15 56.6 0.0 5.5e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA01885.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKA01885.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bud13 PF09736.9 KKA01886.1 - 1.4e-13 51.4 8.0 7.5e-13 49.1 8.0 2.0 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex MFP2b PF12150.8 KKA01886.1 - 0.058 12.7 0.3 0.077 12.3 0.3 1.1 1 0 0 1 1 1 0 Cytosolic motility protein tRNA-synt_2 PF00152.20 KKA01887.1 - 1.9e-74 250.6 0.1 1.9e-74 250.6 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKA01887.1 - 3.5e-06 26.9 0.0 6.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKA01887.1 - 0.011 15.3 0.3 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) IpaC_SipC PF09599.10 KKA01887.1 - 0.71 9.3 4.3 1.1 8.7 4.3 1.2 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) RasGEF PF00617.19 KKA01888.1 - 2e-46 158.4 1.9 2e-46 158.4 1.9 2.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KKA01888.1 - 2.7e-08 34.0 2.9 2.7e-08 34.0 2.9 4.4 4 2 0 4 4 4 1 RasGEF N-terminal motif SH3_1 PF00018.28 KKA01888.1 - 3.8e-06 26.4 0.4 2e-05 24.1 0.2 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKA01888.1 - 0.00011 21.9 0.1 0.00028 20.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKA01888.1 - 0.0093 15.6 0.1 0.026 14.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 KKA01892.1 - 6.6e-53 179.7 4.5 3.8e-51 174.0 4.5 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01892.1 - 6.2e-28 97.8 0.2 1.6e-26 93.1 0.0 2.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA01892.1 - 1.7e-05 24.3 0.0 0.00036 19.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKA01892.1 - 0.00091 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase E2_bind PF08825.10 KKA01892.1 - 0.0019 18.3 1.6 0.0067 16.6 1.6 2.0 1 0 0 1 1 1 1 E2 binding domain Haspin_kinase PF12330.8 KKA01892.1 - 0.0033 16.4 0.0 0.0033 16.4 0.0 2.3 3 1 0 4 4 4 1 Haspin like kinase domain Methyltransf_PK PF05891.12 KKA01894.1 - 1.9e-59 200.8 0.4 2.2e-59 200.6 0.4 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KKA01894.1 - 3e-05 23.9 0.1 7e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KKA01894.1 - 0.00086 18.7 0.1 0.5 9.6 0.0 2.4 2 1 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KKA01894.1 - 0.012 16.2 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 KKA01894.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SAPS PF04499.15 KKA01896.1 - 1.9e-153 511.8 14.0 1.9e-153 511.8 14.0 4.0 2 1 1 4 4 4 1 SIT4 phosphatase-associated protein TFIID_NTD2 PF04494.15 KKA01896.1 - 0.048 13.9 5.4 0.039 14.2 2.4 2.5 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain SOGA PF11365.8 KKA01896.1 - 6 8.1 11.4 0.093 13.9 2.2 2.8 3 1 0 3 3 3 0 Protein SOGA AA_permease PF00324.21 KKA01897.1 - 4e-144 480.8 35.2 4.6e-144 480.6 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA01897.1 - 3.8e-37 128.1 34.5 4.8e-37 127.8 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKA01898.1 - 3.5e-135 451.3 32.2 4e-135 451.1 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA01898.1 - 1e-29 103.7 32.3 1.4e-29 103.3 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 KKA01898.1 - 0.08 13.5 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Pet100 KH_1 PF00013.29 KKA01899.1 - 3.8e-65 215.6 42.6 1.5e-09 37.6 0.3 12.1 13 0 0 13 13 13 8 KH domain KH_2 PF07650.17 KKA01899.1 - 1.4e-07 31.2 34.9 0.012 15.4 0.0 9.1 8 1 1 9 9 9 4 KH domain Secretin_N PF03958.17 KKA01899.1 - 1.9e-05 25.0 0.6 0.11 12.9 0.0 4.5 5 0 0 5 5 5 1 Bacterial type II/III secretion system short domain KH_4 PF13083.6 KKA01899.1 - 9e-05 22.3 6.9 0.11 12.4 0.0 6.1 6 1 1 7 7 7 1 KH domain TFIIE-A_C PF11521.8 KKA01899.1 - 0.0081 16.4 0.7 0.091 13.1 0.2 3.0 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Skp1 PF01466.19 KKA01899.1 - 0.048 13.8 4.6 3.2 7.9 0.2 3.9 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DUF2000 PF09391.10 KKA01899.1 - 0.23 11.4 1.9 11 5.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2000) DUF4974 PF16344.5 KKA01899.1 - 0.52 10.3 8.9 9.4 6.3 0.1 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF4974) SOAR PF16533.5 KKA01899.1 - 6.1 6.9 8.0 5.7 7.0 0.2 3.9 5 0 0 5 5 5 0 STIM1 Orai1-activating region KH_5 PF13184.6 KKA01899.1 - 7.8 6.7 15.0 1.4 9.1 0.1 5.7 5 0 0 5 5 5 0 NusA-like KH domain Ras PF00071.22 KKA01900.1 - 7.6e-51 171.9 0.1 9.6e-51 171.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA01900.1 - 8.5e-35 119.6 0.0 1.4e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA01900.1 - 2.5e-12 46.6 0.1 6e-12 45.4 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKA01900.1 - 2.3e-05 24.4 0.2 5.5e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKA01900.1 - 3.5e-05 23.3 0.1 4.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 KKA01900.1 - 0.0011 18.3 0.5 0.0018 17.6 0.1 1.5 2 0 0 2 2 2 1 Septin nsp9 PF08710.10 KKA01900.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 nsp9 replicase RsgA_GTPase PF03193.16 KKA01900.1 - 0.0027 17.6 0.3 0.76 9.7 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 KKA01900.1 - 0.0053 16.2 0.1 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KKA01900.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Soyouz_module PF14313.6 KKA01900.1 - 0.096 12.5 0.7 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) FSH1 PF03959.13 KKA01902.1 - 2.9e-46 157.8 0.1 3.7e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKA01902.1 - 0.0014 18.5 0.1 0.0026 17.6 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 KKA01902.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase UCH PF00443.29 KKA01903.1 - 8.1e-43 146.8 11.3 8.1e-43 146.8 11.3 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKA01903.1 - 2.9e-11 43.5 24.8 3.3e-11 43.3 18.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKA01903.1 - 6.4e-08 32.8 11.1 6.4e-08 32.8 11.1 3.4 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 KKA01903.1 - 4.3 7.6 5.9 8.6 6.6 0.3 3.6 3 0 0 3 3 3 0 Zinc ribbon domain His_Phos_1 PF00300.22 KKA01904.1 - 6.5e-37 127.1 0.1 7.4e-36 123.7 0.1 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.20 KKA01905.1 - 2e-15 57.2 0.0 2.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain AMMECR1 PF01871.17 KKA01906.1 - 2.1e-32 112.1 0.0 3.9e-32 111.1 0.0 1.4 1 1 0 1 1 1 1 AMMECR1 adh_short PF00106.25 KKA01907.1 - 2.5e-51 173.9 0.1 3.5e-51 173.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKA01907.1 - 1.9e-31 109.4 0.1 2.5e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKA01907.1 - 2.3e-12 47.2 0.0 3.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKA01907.1 - 1.5e-05 24.6 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KKA01907.1 - 0.0018 17.5 0.0 0.003 16.7 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKA01907.1 - 0.032 14.5 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HCBP_related PF06594.11 KKA01908.1 - 0.00012 21.9 0.1 0.00031 20.6 0.1 1.8 1 0 0 1 1 1 1 Haemolysin-type calcium binding protein related domain AMPK1_CBM PF16561.5 KKA01908.1 - 0.0033 17.6 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Polysacc_deac_1 PF01522.21 KKA01909.1 - 2.4e-28 98.5 0.0 4.9e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KKA01909.1 - 0.00097 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 GRIP PF01465.20 KKA01910.1 - 3.2e-13 49.3 1.1 5.5e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 GRIP domain CTP_transf_like PF01467.26 KKA01910.1 - 1.2 9.4 8.1 1.6 9.0 0.1 3.2 2 1 0 2 2 2 0 Cytidylyltransferase-like Ribosomal_S8e PF01201.22 KKA01911.1 - 4.2e-43 146.8 4.7 7.3e-43 146.0 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e PUF PF00806.19 KKA01913.1 - 1.5e-45 150.4 36.1 1.3e-05 24.6 2.0 8.9 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Tho1_MOS11_C PF18592.1 KKA01914.1 - 8.9e-20 70.3 2.5 2.1e-19 69.0 2.5 1.7 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 KKA01914.1 - 6.1e-11 41.8 0.6 1.5e-10 40.5 0.6 1.7 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 KKA01914.1 - 0.071 12.8 0.5 0.46 10.2 0.2 2.2 1 1 1 2 2 2 0 Telomere stability C-terminal RelB_N PF18506.1 KKA01914.1 - 3.4 7.5 13.3 0.38 10.6 2.3 3.5 3 0 0 3 3 3 0 RelB Antitoxin alpha helical domain RRN3 PF05327.11 KKA01914.1 - 5.1 5.5 8.3 6.2 5.2 8.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-RING_4 PF14570.6 KKA01915.1 - 2.4e-19 68.9 11.0 5.5e-19 67.7 11.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KKA01915.1 - 5.2e-05 23.0 6.3 5.2e-05 23.0 6.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KKA01915.1 - 5.8e-05 22.8 0.1 0.00015 21.5 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 KKA01915.1 - 0.0003 20.7 3.3 0.0003 20.7 3.3 2.1 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KKA01915.1 - 0.0027 17.1 1.5 0.0027 17.1 1.5 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger Nexin_C PF08628.12 KKA01915.1 - 0.008 16.7 1.2 3.8 8.1 0.3 2.5 2 0 0 2 2 2 2 Sorting nexin C terminal zf-C3HC4 PF00097.25 KKA01915.1 - 0.019 14.8 9.8 0.06 13.2 9.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKA01915.1 - 0.02 15.2 10.3 0.02 15.2 10.3 1.8 2 0 0 2 2 1 0 Ring finger domain DcpS PF05652.12 KKA01915.1 - 0.081 13.8 3.0 0.87 10.5 0.1 2.6 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal E2F_CC-MB PF16421.5 KKA01915.1 - 0.11 12.9 0.3 0.11 12.9 0.3 2.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Prok-RING_4 PF14447.6 KKA01915.1 - 0.21 11.5 8.7 7.7 6.5 9.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKA01915.1 - 1.5 8.8 9.5 4.1 7.4 9.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain OPT PF03169.15 KKA01916.1 - 8.2e-110 368.2 49.2 9.4e-110 368.1 49.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HAD_2 PF13419.6 KKA01917.1 - 8.7e-18 65.0 0.0 1.1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKA01917.1 - 7.1e-10 39.5 0.0 8.7e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKA01917.1 - 7.6e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KKA01917.1 - 0.0075 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PHINT_rpt PF14882.6 KKA01917.1 - 0.088 13.1 0.2 6.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Phage-integrase repeat unit Rap1-DNA-bind PF09197.10 KKA01917.1 - 0.1 13.2 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 Rap1, DNA-binding Cyclin PF08613.11 KKA01918.1 - 2.1e-30 106.2 4.9 2.1e-30 106.2 4.9 2.8 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KKA01918.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 Cyclin, N-terminal domain B_lectin PF01453.24 KKA01918.1 - 3.9 8.1 7.9 5.3 7.6 0.1 3.9 3 1 2 5 5 5 0 D-mannose binding lectin 2-Hacid_dh_C PF02826.19 KKA01919.1 - 1.6e-51 174.2 0.0 2.6e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKA01919.1 - 1e-35 122.3 0.1 1.4e-35 121.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKA01919.1 - 0.0037 17.5 1.1 0.02 15.0 0.3 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KKA01919.1 - 0.03 14.8 0.2 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 KKA01919.1 - 0.045 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AceK PF06315.11 KKA01919.1 - 0.069 11.6 0.1 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DHO_dh PF01180.21 KKA01920.1 - 2.4e-96 322.4 0.4 2.9e-96 322.2 0.4 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KKA01920.1 - 0.14 11.2 0.1 2.7 7.0 0.6 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase TPR_19 PF14559.6 KKA01921.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CdiI_2 PF18593.1 KKA01921.1 - 0.22 12.2 2.1 1.2 9.9 0.1 2.9 3 1 0 3 3 3 0 CdiI immunity protein DUF1689 PF07954.11 KKA01922.1 - 5.5e-25 88.5 2.7 1.8e-24 86.8 0.3 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1689) HNHc_6 PF16784.5 KKA01922.1 - 0.056 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease Acyl_transf_3 PF01757.22 KKA01922.1 - 0.1 11.6 0.6 0.14 11.2 0.6 1.1 1 0 0 1 1 1 0 Acyltransferase family zf-CCHC PF00098.23 KKA01923.1 - 1.8e-09 37.2 37.8 1.6e-05 24.7 0.5 5.4 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_3 PF13917.6 KKA01923.1 - 0.00053 19.9 19.9 0.23 11.4 0.0 4.9 3 1 1 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.6 KKA01923.1 - 0.034 14.0 0.5 0.034 14.0 0.5 4.0 4 0 0 4 4 4 0 Zinc knuckle Mu-like_Com PF10122.9 KKA01923.1 - 0.094 12.2 16.8 0.49 9.9 1.1 4.2 3 1 1 4 4 4 0 Mu-like prophage protein Com zf-CCHC_4 PF14392.6 KKA01923.1 - 0.097 12.4 26.4 0.66 9.8 0.4 5.4 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.6 KKA01923.1 - 0.13 12.1 0.1 0.13 12.1 0.1 5.0 5 0 0 5 5 5 0 Zinc knuckle Pmp3 PF01679.17 KKA01924.1 - 2.8e-15 56.2 9.8 3.5e-15 55.9 9.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0029 PF01205.19 KKA01925.1 - 6.9e-14 52.1 0.1 8.3e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Cyclin_N PF00134.23 KKA01926.1 - 5.4e-14 52.0 0.1 5.4e-14 52.0 0.1 2.1 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.11 KKA01926.1 - 4.4e-06 27.2 3.5 1.5e-05 25.4 0.1 2.3 2 0 0 2 2 2 1 Cyclin Pox_mRNA-cap PF03341.13 KKA01926.1 - 0.0061 15.9 1.3 0.0082 15.5 0.2 1.8 2 1 0 2 2 2 1 Poxvirus mRNA capping enzyme, small subunit DUF1768 PF08719.11 KKA01926.1 - 0.18 12.0 1.5 0.35 11.1 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) DUF572 PF04502.13 KKA01928.1 - 1.3e-14 54.6 21.1 3.8e-14 53.1 21.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF2757 PF10955.8 KKA01928.1 - 3.7e-05 23.9 3.3 0.41 10.9 0.1 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF2757) zinc_ribbon_10 PF10058.9 KKA01928.1 - 0.038 13.7 2.1 7 6.5 0.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 KKA01928.1 - 0.16 12.0 1.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 KKA01928.1 - 0.25 10.9 1.2 3.9 7.1 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding LptF_LptG PF03739.14 KKA01928.1 - 1.6 7.5 6.0 0.44 9.3 1.6 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG 5_3_exonuc PF01367.20 KKA01928.1 - 7 7.3 12.5 0.073 13.7 3.6 2.3 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Arf PF00025.21 KKA01929.1 - 3e-68 228.7 0.5 3.4e-68 228.5 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKA01929.1 - 6.8e-15 55.4 0.2 9.3e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKA01929.1 - 2.1e-13 50.2 0.1 2.2e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKA01929.1 - 1.3e-12 47.5 0.1 1.5e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKA01929.1 - 3.8e-11 42.8 0.1 4.5e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKA01929.1 - 1.4e-10 40.9 2.2 6e-08 32.2 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KKA01929.1 - 8.4e-07 29.1 0.4 1.4e-06 28.4 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.14 KKA01929.1 - 0.098 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 KKA01930.1 - 8.2e-78 259.8 0.1 9.3e-78 259.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKA01930.1 - 6.6e-15 55.1 0.0 7.5e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA01930.1 - 8.9e-15 55.0 0.1 1.3e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKA01930.1 - 1.1e-14 54.2 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKA01930.1 - 2e-12 47.0 1.6 5.9e-09 35.5 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KKA01930.1 - 1.2e-10 41.2 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA01930.1 - 2.6e-05 24.2 0.1 4.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KKA01930.1 - 0.0086 15.7 0.4 0.87 9.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KKA01930.1 - 0.021 14.5 0.4 0.041 13.5 0.2 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KKA01930.1 - 0.055 13.6 0.3 0.099 12.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKA01930.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KKA01930.1 - 0.11 12.5 0.9 6.6 6.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KKA01930.1 - 0.13 12.1 0.1 15 5.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase 6PF2K PF01591.18 KKA01930.1 - 0.15 11.4 0.3 0.3 10.4 0.3 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 KKA01930.1 - 0.16 12.5 0.2 0.31 11.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter OHCU_decarbox PF09349.10 KKA01931.1 - 4.1e-39 134.5 0.3 4.6e-39 134.4 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase FapA PF03961.13 KKA01931.1 - 0.047 12.3 1.2 0.057 12.0 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MARVEL PF01284.23 KKA01933.1 - 0.0028 17.7 2.3 0.0046 17.0 2.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2142 PF09913.9 KKA01933.1 - 0.017 14.0 0.2 0.034 13.0 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Ku_PK_bind PF08785.11 KKA01933.1 - 2.6 8.2 5.9 67 3.7 1.9 3.2 2 1 1 3 3 3 0 Ku C terminal domain like Cullin PF00888.22 KKA01934.1 - 8.2e-75 252.6 26.0 1e-74 252.3 26.0 1.1 1 0 0 1 1 1 1 Cullin family HMGL-like PF00682.19 KKA01935.1 - 1.2e-84 284.0 0.2 1.7e-84 283.5 0.2 1.2 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 KKA01935.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Scm3 PF10384.9 KKA01936.1 - 7.8e-16 57.6 1.1 1.6e-15 56.5 0.2 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 Pro_isomerase PF00160.21 KKA01937.1 - 1e-45 155.8 0.2 4.5e-45 153.8 0.2 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KKA01937.1 - 5.9e-12 44.9 5.6 8e-05 22.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKA01937.1 - 1.4e-07 31.1 2.1 0.015 15.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF3856 PF12968.7 KKA01937.1 - 0.0015 18.6 0.1 0.0027 17.8 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 KKA01937.1 - 0.0015 18.8 0.0 5.1 7.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKA01937.1 - 0.0033 17.5 0.2 0.46 10.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKA01937.1 - 0.011 15.4 3.2 0.54 10.0 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 KKA01937.1 - 0.016 15.3 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKA01937.1 - 0.026 14.6 0.6 0.91 9.6 0.1 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KKA01937.1 - 0.06 13.4 0.2 3.4 7.9 0.0 2.8 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKA01937.1 - 0.063 13.7 0.2 5.1 7.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKA01937.1 - 0.14 12.9 0.1 2.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0122 PF04297.14 KKA01937.1 - 2 8.7 7.2 1.5 9.1 0.8 2.7 2 1 1 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like MIT PF04212.18 KKA01937.1 - 3.2 7.9 7.3 0.45 10.6 0.4 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Transket_pyr PF02779.24 KKA01938.1 - 9.4e-46 155.7 0.0 2.6e-45 154.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKA01938.1 - 3.5e-36 123.8 0.0 6.2e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Flavi_capsid PF01003.19 KKA01938.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C Acatn PF13000.7 KKA01939.1 - 3e-174 580.6 24.6 1.6e-164 548.4 19.4 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Scs3p PF10261.9 KKA01940.1 - 1e-22 80.8 14.3 7.4e-21 74.8 1.3 2.6 2 1 1 3 3 3 2 Inositol phospholipid synthesis and fat-storage-inducing TM NADHdeh_related PF10125.9 KKA01940.1 - 0.0081 15.6 0.3 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 NADH dehydrogenase I, subunit N related protein DUF2842 PF11003.8 KKA01940.1 - 9.3 6.6 11.0 6.3 7.1 0.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2842) Med31 PF05669.12 KKA01941.1 - 4.5e-18 65.0 2.0 5.4e-18 64.8 2.0 1.2 1 0 0 1 1 1 1 SOH1 CPSase_L_D2 PF02786.17 KKA01942.1 - 2.3e-83 278.8 0.2 4.3e-83 278.0 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KKA01942.1 - 7.9e-63 211.8 0.0 1.4e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KKA01942.1 - 9e-40 135.7 0.0 2e-39 134.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKA01942.1 - 6.3e-30 103.5 0.0 2.1e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KKA01942.1 - 6.7e-28 98.0 0.1 1.2e-27 97.1 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KKA01942.1 - 2.9e-17 62.3 5.8 2.9e-17 62.3 5.8 2.0 2 0 0 2 2 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KKA01942.1 - 3.9e-09 36.2 2.0 0.00013 21.8 0.2 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KKA01942.1 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKA01942.1 - 1.7e-06 27.7 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KKA01942.1 - 1.8e-06 28.1 0.0 4.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KKA01942.1 - 0.0042 17.8 0.5 1 10.1 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 KKA01942.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KKA01942.1 - 0.012 15.6 0.4 0.051 13.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_D23 PF16576.5 KKA01942.1 - 0.012 14.8 0.2 0.23 10.7 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 KKA01942.1 - 0.22 11.2 2.1 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain RnfC_N PF13375.6 KKA01942.1 - 0.6 10.1 3.3 2.7 8.0 2.7 2.4 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 KKA01942.1 - 3.5 7.5 6.4 3.4 7.6 1.0 3.1 2 1 2 4 4 4 0 Glycine cleavage H-protein ADH_zinc_N PF00107.26 KKA01943.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Kinetochor_Ybp2 PF08568.10 KKA01944.1 - 3e-09 35.9 9.1 3e-09 35.9 9.1 1.9 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin BCDHK_Adom3 PF10436.9 KKA01945.1 - 8e-26 90.8 3.0 1.5e-25 89.9 3.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKA01945.1 - 3.7e-08 33.9 0.3 8.9e-06 26.2 0.3 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKA01945.1 - 0.0029 17.4 1.0 0.0065 16.3 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RrnaAD PF00398.20 KKA01947.1 - 2.4e-55 187.5 1.2 3e-55 187.1 1.2 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KKA01947.1 - 6.6e-06 26.8 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA01947.1 - 0.00026 21.7 0.3 0.0031 18.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA01947.1 - 0.0025 17.7 0.0 0.0032 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKA01947.1 - 0.003 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKA01947.1 - 0.0041 16.9 0.0 0.0081 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA01947.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KKA01947.1 - 0.059 12.7 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 KKA01947.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.6 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 FA_desaturase PF00487.24 KKA01948.1 - 1.8e-17 64.0 17.5 1.8e-17 64.0 17.5 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKA01948.1 - 1.7e-16 60.1 0.0 3.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_7 PF13241.6 KKA01949.1 - 2.1e-19 69.9 0.0 5e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KKA01949.1 - 1e-07 31.3 0.1 1.8e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KKA01949.1 - 2.1e-05 24.0 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Yqai PF09466.10 KKA01949.1 - 0.17 12.2 0.7 0.93 9.9 0.3 2.3 2 0 0 2 2 2 0 Hypothetical protein Yqai RRM_1 PF00076.22 KKA01950.1 - 9.5e-35 118.3 3.9 4.1e-12 45.7 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKA01950.1 - 3.5e-05 23.4 0.0 0.0037 16.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KKA01950.1 - 0.002 18.3 0.3 0.35 11.1 0.1 2.6 2 0 0 2 2 2 2 BRCA1-associated protein 2 OGG_N PF07934.12 KKA01951.1 - 7.4e-06 26.1 6.1 8.1e-06 25.9 3.7 2.3 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KKA01951.1 - 3.9e-05 24.1 0.0 0.00018 21.9 0.0 1.9 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KKA01951.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4292 PF14125.6 KKA01951.1 - 0.038 13.7 0.3 0.071 12.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) HU-CCDC81_bac_2 PF18175.1 KKA01952.1 - 0.054 13.4 0.9 14 5.7 0.0 3.7 3 1 1 4 4 4 0 CCDC81-like prokaryotic HU domain 2 IZUMO PF15005.6 KKA01952.1 - 0.099 13.2 5.7 0.18 12.3 5.3 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Cornichon PF03311.14 KKA01953.1 - 1.1e-41 142.0 11.5 1.3e-41 141.8 11.5 1.0 1 0 0 1 1 1 1 Cornichon protein CBS PF00571.28 KKA01954.1 - 2e-21 76.2 2.4 6.9e-08 32.8 0.0 5.3 5 0 0 5 5 5 5 CBS domain SNF2_N PF00176.23 KKA01955.1 - 2e-52 178.0 0.3 4.3e-52 177.0 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA01955.1 - 2.7e-15 56.6 0.0 1.1e-14 54.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA01955.1 - 5.1e-08 33.1 0.1 5.1e-08 33.1 0.1 3.3 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit Sec20 PF03908.13 KKA01955.1 - 0.023 14.6 5.1 0.18 11.7 0.1 4.2 3 1 0 3 3 3 0 Sec20 AHD PF17793.1 KKA01955.1 - 0.032 14.0 0.4 0.12 12.1 0.4 2.1 1 0 0 1 1 1 0 ANC1 homology domain (AHD) zf-RING_5 PF14634.6 KKA01955.1 - 0.039 13.9 7.3 0.074 13.0 7.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain BA14K PF07886.11 KKA01955.1 - 0.041 13.8 0.7 11 6.0 0.2 2.8 2 0 0 2 2 2 0 BA14K-like protein zf-RING_UBOX PF13445.6 KKA01955.1 - 0.079 13.0 4.2 0.18 11.9 4.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KKA01955.1 - 0.27 11.4 3.1 0.63 10.2 3.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KKA01955.1 - 0.69 9.8 8.9 1.4 8.9 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKA01955.1 - 0.96 9.8 7.6 1.8 8.9 7.6 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KKA01955.1 - 2.5 8.0 5.9 5.5 6.9 5.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HRI1 PF16815.5 KKA01956.1 - 1.8e-26 93.3 0.0 2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 DUF1256 PF06866.11 KKA01956.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) HRI1 PF16815.5 KKA01957.1 - 2.1e-27 96.3 0.0 2.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein HRI1 PI-PLC-X PF00388.19 KKA01958.1 - 3.4e-50 169.4 0.1 8.1e-50 168.2 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKA01958.1 - 1.1e-32 112.7 0.6 3.3e-32 111.2 0.6 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KKA01958.1 - 4.1e-06 27.0 0.1 2.3e-05 24.6 0.1 2.3 2 1 0 2 2 2 1 C2 domain EF-hand_1 PF00036.32 KKA01958.1 - 0.00031 20.1 0.2 0.00094 18.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KKA01958.1 - 0.00038 20.8 4.4 0.00041 20.8 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_like PF09279.11 KKA01958.1 - 0.00099 19.6 1.6 0.0038 17.7 0.9 2.4 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.6 KKA01958.1 - 0.0026 17.5 1.2 0.0058 16.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KKA01958.1 - 0.0061 16.4 0.7 0.032 14.2 0.4 2.5 2 0 0 2 2 1 1 EF-hand domain EF-hand_5 PF13202.6 KKA01958.1 - 0.017 14.6 0.2 0.043 13.3 0.2 1.7 1 0 0 1 1 1 0 EF hand Pro-kuma_activ PF09286.11 KKA01958.1 - 0.041 14.2 0.1 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain MaoC_dehydratas PF01575.19 KKA01958.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 MaoC like domain EF-hand_10 PF14788.6 KKA01958.1 - 1.4 8.9 8.3 0.073 13.0 0.5 2.9 3 0 0 3 3 3 0 EF hand ABC_membrane PF00664.23 KKA01960.1 - 6.6e-38 130.9 13.4 9.9e-38 130.3 13.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKA01960.1 - 2.4e-31 109.1 0.2 2.4e-31 109.1 0.2 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KKA01960.1 - 6.8e-05 22.4 0.0 0.0008 18.9 0.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KKA01960.1 - 0.00018 20.5 0.3 0.00039 19.4 0.0 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KKA01960.1 - 0.0009 19.5 0.1 0.02 15.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKA01960.1 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Guanylate_kin PF00625.21 KKA01960.1 - 0.0057 16.4 0.0 0.051 13.3 0.0 2.3 2 0 0 2 2 2 1 Guanylate kinase AAA PF00004.29 KKA01960.1 - 0.01 16.2 0.2 0.096 13.1 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKA01960.1 - 0.015 15.3 0.0 0.062 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KKA01960.1 - 0.017 14.8 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKA01960.1 - 0.044 13.7 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KKA01960.1 - 0.15 11.8 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KKA01960.1 - 0.22 11.8 0.7 2.4 8.5 0.7 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Yip1 PF04893.17 KKA01960.1 - 1.1 8.9 13.3 0.58 9.9 0.4 3.1 3 0 0 3 3 3 0 Yip1 domain Kelch_4 PF13418.6 KKA01961.1 - 3.8e-27 94.0 5.4 0.00011 22.1 0.0 6.6 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KKA01961.1 - 4.3e-25 87.5 0.0 0.00026 21.2 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 KKA01961.1 - 3e-21 75.3 0.3 3e-21 75.3 0.3 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 KKA01961.1 - 6.5e-21 73.9 0.5 0.0011 18.9 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KKA01961.1 - 4.2e-20 71.3 5.0 0.0035 17.6 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KKA01961.1 - 1.3e-12 47.2 10.5 0.027 14.5 0.1 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KKA01961.1 - 5.2e-11 42.0 8.8 0.17 11.5 0.1 6.8 7 0 0 7 7 7 4 Kelch motif CAF1C_H4-bd PF12265.8 KKA01962.1 - 1e-14 54.5 0.2 2.4e-14 53.3 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KKA01962.1 - 7.7e-12 45.5 4.4 0.018 15.9 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat DNA_pol_phi PF04931.13 KKA01964.1 - 6.3e-124 414.8 47.3 6.3e-124 414.8 47.3 1.4 2 0 0 2 2 2 1 DNA polymerase phi UNC45-central PF11701.8 KKA01964.1 - 0.05 13.6 1.7 0.21 11.5 1.1 2.3 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central PGM_PMM_I PF02878.16 KKA01965.1 - 3.5e-19 68.9 0.1 1.6e-09 37.6 0.0 2.4 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KKA01965.1 - 3.2e-08 33.6 0.0 6.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KKA01965.1 - 0.00032 21.3 0.3 0.0021 18.7 0.2 2.4 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1981 PF09324.10 KKA01965.1 - 0.007 16.2 0.1 0.025 14.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Peptidase_S8 PF00082.22 KKA01967.1 - 1.3e-31 110.0 9.1 2.9e-31 108.8 8.9 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKA01967.1 - 8.1e-11 42.4 0.1 2.5e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Peptidase inhibitor I9 Fcf1 PF04900.12 KKA01968.1 - 6.6e-25 87.4 0.7 6.6e-25 87.4 0.7 1.8 2 0 0 2 2 2 1 Fcf1 NPR2 PF06218.11 KKA01969.1 - 8.8e-86 288.4 21.9 3.6e-76 256.7 10.9 2.6 1 1 1 3 3 3 2 Nitrogen permease regulator 2 Kinesin PF00225.23 KKA01970.1 - 1.1e-94 317.2 8.2 6.4e-62 209.4 4.1 4.1 3 1 1 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 KKA01970.1 - 2.6e-17 63.1 0.1 2.6e-17 63.1 0.1 4.1 3 1 1 4 4 4 1 Microtubule binding Alg6_Alg8 PF03155.15 KKA01971.1 - 8.6e-51 173.4 29.8 7.9e-50 170.2 29.8 2.3 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyoxal_oxid_N PF07250.11 KKA01971.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Cyclin PF08613.11 KKA01972.1 - 2.4e-33 115.8 0.6 6.1e-33 114.5 0.6 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKA01972.1 - 0.00042 20.0 0.6 0.00094 18.9 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ras PF00071.22 KKA01973.1 - 5.5e-47 159.4 1.2 1.9e-46 157.6 1.2 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKA01973.1 - 1.1e-33 116.0 0.1 1.9e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA01973.1 - 6.5e-14 51.8 0.1 7.4e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKA01973.1 - 8.2e-09 35.3 0.5 2e-07 30.7 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKA01973.1 - 3.3e-08 33.2 0.1 4.1e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA01973.1 - 1.8e-07 31.2 0.0 3.3e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKA01973.1 - 0.00024 21.1 1.2 0.0043 17.0 0.0 2.8 3 1 0 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 KKA01973.1 - 0.00059 19.7 0.2 0.019 14.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KKA01973.1 - 0.00079 20.0 0.7 0.0013 19.2 0.7 1.3 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KKA01973.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KKA01973.1 - 0.0018 18.5 0.1 0.0031 17.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKA01973.1 - 0.0047 16.7 0.1 0.0083 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKA01973.1 - 0.0059 17.0 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KKA01973.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KKA01973.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 KKA01973.1 - 0.015 14.6 0.1 0.085 12.1 0.1 2.0 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 KKA01973.1 - 0.015 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KKA01973.1 - 0.02 14.5 0.4 0.1 12.2 0.0 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KKA01973.1 - 0.053 14.0 0.5 0.089 13.3 0.5 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KKA01973.1 - 0.069 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Ribo_biogen_C PF04034.13 KKA01974.1 - 3.5e-52 175.4 0.0 5.2e-52 174.9 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KKA01974.1 - 5.7e-15 54.8 0.1 9.6e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nop14 PF04147.12 KKA01974.1 - 3.6 5.7 11.7 5.1 5.2 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_1 PF00515.28 KKA01975.1 - 5.4e-17 60.8 8.5 2.2e-05 24.1 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KKA01975.1 - 4.4e-16 58.4 2.4 1.1e-15 57.1 2.4 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 KKA01975.1 - 2.7e-15 55.2 4.4 6.4e-05 22.8 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKA01975.1 - 1.2e-12 47.3 11.3 1.8e-07 30.7 0.4 3.5 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KKA01975.1 - 1e-09 37.8 9.2 0.0034 17.5 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKA01975.1 - 1.2e-07 32.3 5.9 0.011 16.4 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKA01975.1 - 1.4e-05 25.5 3.7 0.21 12.5 0.1 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKA01975.1 - 4.6e-05 23.5 3.3 0.12 12.8 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat STI1 PF17830.1 KKA01975.1 - 0.00011 22.0 7.0 0.00011 22.0 7.0 2.4 1 1 1 2 2 2 1 STI1 domain TPR_12 PF13424.6 KKA01975.1 - 0.001 19.3 4.6 0.36 11.2 0.7 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKA01975.1 - 0.0031 17.6 0.2 0.024 14.7 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKA01975.1 - 0.0044 16.9 2.4 0.6 10.3 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKA01975.1 - 0.021 15.4 5.7 0.85 10.2 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat GerD PF17898.1 KKA01975.1 - 0.06 13.3 5.3 0.49 10.4 5.0 2.6 2 1 0 2 2 2 0 Spore germination GerD central core domain TPR_10 PF13374.6 KKA01975.1 - 1.5 8.8 4.0 63 3.6 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKA01975.1 - 1.6 9.5 6.5 3.7 8.4 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DNA_processg_A PF02481.15 KKA01976.1 - 0.012 14.9 0.6 0.019 14.2 0.6 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A Asp5 PF17000.5 KKA01976.1 - 0.057 13.6 0.1 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 CTC1_2 PF15491.6 KKA01976.1 - 0.45 9.8 8.7 0.12 11.7 2.9 2.0 2 0 0 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 DNA_pol_A_exo1 PF01612.20 KKA01977.1 - 2.1e-44 151.4 1.1 4.7e-44 150.2 1.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 KKA01977.1 - 1.6e-12 47.2 0.0 4.7e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 KKA01977.1 - 1.9e-10 41.3 1.4 1.9e-10 41.3 1.4 3.2 2 1 0 2 2 2 1 PMC2NT (NUC016) domain RsmJ PF04378.13 KKA01977.1 - 0.038 13.2 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ HlyIII PF03006.20 KKA01978.1 - 7.4e-56 189.4 16.5 8.7e-56 189.1 16.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related DHHC PF01529.20 KKA01979.1 - 3.1e-27 95.3 18.2 3.1e-27 95.3 18.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sin3a_C PF16879.5 KKA01980.1 - 2e-50 172.1 9.0 2e-50 172.1 9.0 3.2 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KKA01980.1 - 4.2e-45 151.6 7.3 1.5e-16 60.3 0.9 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KKA01980.1 - 2e-42 143.2 1.8 4e-42 142.2 0.2 2.5 2 0 0 2 2 2 1 Sin3 family co-repressor COX5A PF02284.16 KKA01980.1 - 0.067 13.2 1.3 17 5.5 0.0 4.4 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va RNA_pol_L_2 PF13656.6 KKA01981.1 - 1.2e-25 89.0 0.1 1.5e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKA01981.1 - 4.6e-08 32.4 0.0 7.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Thymidylate_kin PF02223.17 KKA01981.1 - 0.0025 17.5 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase Pkinase PF00069.25 KKA01982.1 - 2.6e-68 230.2 0.1 4e-68 229.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA01982.1 - 1.2e-37 129.6 0.0 2.2e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KKA01982.1 - 1.4e-21 76.4 0.1 4.4e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KKA01982.1 - 3.7e-14 52.7 0.0 2e-13 50.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKA01982.1 - 0.02 13.7 0.3 0.059 12.1 0.3 1.8 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KKA01982.1 - 0.2 11.6 0.0 0.54 10.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2076 PF09849.9 KKA01983.1 - 1.1e-07 32.2 11.8 1.4e-07 31.9 11.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KKA01983.1 - 0.00023 21.2 2.6 0.00037 20.5 2.6 1.4 1 0 0 1 1 1 1 CHCH domain RskA PF10099.9 KKA01983.1 - 0.0087 16.4 6.8 0.012 15.9 6.8 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Romo1 PF10247.9 KKA01983.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 TFIIA PF03153.13 KKA01983.1 - 9 6.2 15.8 9.9 6.0 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAF4 PF05236.14 KKA01984.1 - 1.5e-21 77.4 10.3 2e-21 77.0 10.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family XRN_M PF17846.1 KKA01984.1 - 0.29 10.1 4.7 0.45 9.4 4.7 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Exonuc_VII_L PF02601.15 KKA01984.1 - 0.29 10.7 11.2 1.5 8.3 11.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit SAP PF02037.27 KKA01985.1 - 2.5e-09 36.7 0.4 5.4e-09 35.6 0.4 1.5 1 0 0 1 1 1 1 SAP domain HI0933_like PF03486.14 KKA01985.1 - 0.0074 15.0 3.1 0.0074 15.0 3.1 1.7 2 0 0 2 2 2 1 HI0933-like protein TSSC4 PF15264.6 KKA01985.1 - 0.77 10.0 7.6 1.5 9.0 1.1 2.7 1 1 1 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 FapA PF03961.13 KKA01985.1 - 7.8 5.0 18.1 0.21 10.1 10.6 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Polyketide_cyc PF03364.20 KKA01986.1 - 2.3e-10 40.8 0.0 3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_5 PF01795.19 KKA01986.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family MMM1 PF10296.9 KKA01987.1 - 0.00011 21.4 3.8 0.00032 19.9 3.8 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF5446 PF17522.2 KKA01987.1 - 0.12 12.5 0.2 0.12 12.5 0.2 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5446) PX PF00787.24 KKA01988.1 - 4.7e-12 45.9 0.3 4.7e-12 45.9 0.3 2.8 4 0 0 4 4 4 1 PX domain Peroxin-13_N PF04088.13 KKA01988.1 - 0.052 13.8 0.2 0.052 13.8 0.2 2.5 3 0 0 3 3 3 0 Peroxin 13, N-terminal region RTC PF01137.21 KKA01989.1 - 9.9e-29 100.1 0.0 2e-28 99.1 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KKA01989.1 - 6.1e-07 29.9 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF410 PF04190.13 KKA01990.1 - 5.3e-38 131.3 2.1 6.7e-38 130.9 2.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF410) GBP_C PF02841.14 KKA01990.1 - 0.031 13.7 0.4 0.031 13.7 0.4 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain PLA2_B PF01735.18 KKA01991.1 - 2.5e-155 517.7 7.8 3.1e-155 517.3 7.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KKA01991.1 - 0.035 14.3 3.2 0.079 13.2 2.6 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PLA2_B PF01735.18 KKA01992.1 - 4.1e-186 619.2 6.7 4.9e-186 618.9 6.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KKA01992.1 - 0.026 14.7 1.1 0.06 13.6 1.1 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PLA2_B PF01735.18 KKA01993.1 - 4.3e-186 619.1 6.5 5.4e-186 618.8 6.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KKA01993.1 - 0.026 14.7 1.4 0.064 13.5 1.4 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RHD3 PF05879.12 KKA01995.1 - 5.1e-150 501.1 32.6 6.7e-150 500.7 32.6 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KKA01995.1 - 1.2e-12 47.7 0.5 1.2e-12 47.7 0.5 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KKA01995.1 - 3.5e-06 27.1 0.0 1.5e-05 25.1 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KKA01995.1 - 2.4e-05 24.4 0.4 2.4e-05 24.4 0.4 3.8 3 2 1 4 4 4 1 Dynamin family AAA_28 PF13521.6 KKA01995.1 - 0.0006 20.1 0.0 0.035 14.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KKA01995.1 - 0.0029 17.8 0.1 0.014 15.6 0.1 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IPPT PF01715.17 KKA01995.1 - 0.0047 16.8 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 IPP transferase RsgA_GTPase PF03193.16 KKA01995.1 - 0.037 13.9 1.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KKA01995.1 - 0.07 13.6 0.7 0.46 11.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Bcr-Abl_Oligo PF09036.10 KKA01995.1 - 0.092 12.8 1.2 16 5.5 0.0 3.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain AAA_14 PF13173.6 KKA01995.1 - 0.79 9.8 0.0 0.79 9.8 0.0 3.8 2 1 1 3 3 3 0 AAA domain Mit_ribos_Mrp51 PF11709.8 KKA01995.1 - 2.3 7.7 6.5 8.7 5.8 6.5 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF3698 PF12479.8 KKA01995.1 - 3.3 8.3 6.6 11 6.7 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3698) PIN_4 PF13638.6 KKA01996.1 - 7.2e-13 49.0 5.0 7.2e-13 49.0 5.0 2.7 3 1 0 3 3 3 1 PIN domain tRNA-synt_1c PF00749.21 KKA01997.1 - 1.7e-104 349.1 0.0 4.8e-104 347.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKA01997.1 - 4.6e-37 127.5 4.6 4e-35 121.2 0.1 3.1 3 1 1 4 4 4 2 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 KKA01997.1 - 2.2e-17 63.5 2.8 4.9e-17 62.4 2.8 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 KKA01997.1 - 4.4e-14 53.2 4.4 8.9e-14 52.2 4.4 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ras PF00071.22 KKA01998.1 - 3.5e-47 160.0 0.2 4.6e-47 159.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA01998.1 - 3.2e-35 121.0 0.0 6.5e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA01998.1 - 2.9e-11 43.1 0.1 4.3e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKA01998.1 - 1.1e-07 31.6 0.0 5.4e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKA01998.1 - 5.4e-07 29.2 0.1 6.8e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA01998.1 - 6.8e-05 22.9 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKA01998.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KKA01998.1 - 0.019 14.7 0.7 0.05 13.3 0.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKA01998.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KKA01998.1 - 0.032 14.1 0.2 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DAGK_cat PF00781.24 KKA01999.1 - 5.4e-21 74.5 0.0 9.7e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4502 PF14950.6 KKA01999.1 - 1.8 8.0 6.4 3.2 7.1 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) RasGAP_C PF03836.15 KKA02000.1 - 6.4e-15 55.5 7.7 6.4e-15 55.5 7.7 5.0 6 0 0 6 6 6 1 RasGAP C-terminus IQ PF00612.27 KKA02000.1 - 2.3e-08 33.1 13.8 3.9 7.5 0.0 8.8 9 0 0 9 9 9 4 IQ calmodulin-binding motif CH PF00307.31 KKA02000.1 - 4.7e-08 33.2 3.4 9.2e-08 32.2 0.5 3.2 2 0 0 2 2 2 1 Calponin homology (CH) domain HSP90 PF00183.18 KKA02001.1 - 1.3e-212 707.3 33.0 1.8e-212 706.9 33.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KKA02001.1 - 3.3e-13 50.1 0.1 6.8e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKA02001.1 - 1.6e-09 37.7 0.1 5.9e-09 35.9 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3280 PF11684.8 KKA02001.1 - 0.13 12.7 0.2 0.37 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) LOH1CR12 PF10158.9 KKA02001.1 - 1 9.4 5.9 2 8.4 0.2 2.8 2 0 0 2 2 2 0 Tumour suppressor protein CPSF100_C PF13299.6 KKA02001.1 - 9.4 6.4 10.7 8.8 6.5 5.4 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RTP1_C1 PF10363.9 KKA02002.1 - 1.5e-23 83.1 2.0 3.1e-23 82.1 0.2 2.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Ank_2 PF12796.7 KKA02003.1 - 6.6e-22 77.9 2.1 6.5e-14 52.3 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KKA02003.1 - 6.9e-12 45.2 0.3 1e-05 25.7 0.3 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KKA02003.1 - 4.3e-11 42.0 0.1 0.0002 21.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KKA02003.1 - 7.3e-11 42.4 0.0 0.00011 22.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKA02003.1 - 7.5e-10 38.9 0.0 2.9e-05 24.3 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) BTV_NS2 PF04514.12 KKA02003.1 - 0.072 11.9 1.8 0.11 11.4 1.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TIP49 PF06068.13 KKA02005.1 - 2.1e-127 425.2 8.0 1.3e-125 419.3 8.0 2.1 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KKA02005.1 - 7.1e-24 83.7 0.7 5.3e-23 80.9 0.7 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KKA02005.1 - 1.8e-05 25.2 1.3 0.0065 16.9 0.0 3.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKA02005.1 - 3.6e-05 23.6 1.4 0.0039 17.0 0.2 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKA02005.1 - 0.0016 18.7 0.1 0.94 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KKA02005.1 - 0.022 15.0 0.1 0.063 13.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain Exonuc_V_gamma PF04257.14 KKA02005.1 - 0.083 11.1 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Zeta_toxin PF06414.12 KKA02005.1 - 0.1 11.9 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KKA02005.1 - 0.11 12.9 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 KKA02005.1 - 0.13 12.3 1.8 0.13 12.2 0.4 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_C PF00137.21 KKA02006.1 - 1.2e-32 112.1 28.6 6.7e-18 64.8 11.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KKA02006.1 - 6.3 6.6 6.6 7.5 6.3 0.6 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain FAD_SOX PF18371.1 KKA02007.1 - 0.012 15.9 0.1 0.041 14.2 0.1 1.9 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase CTK3_C PF12350.8 KKA02007.1 - 0.016 15.3 2.0 0.056 13.6 2.0 2.0 1 1 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus TEX12 PF15219.6 KKA02007.1 - 0.62 10.4 5.3 0.35 11.2 1.2 2.5 2 1 1 3 3 3 0 Testis-expressed 12 WAC_Acf1_DNA_bd PF10537.9 KKA02008.1 - 5.4e-28 97.5 2.4 5.4e-28 97.5 2.4 3.0 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KKA02008.1 - 1.1e-05 25.8 0.0 7.1e-05 23.2 0.0 2.5 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Ubiq_cyt_C_chap PF03981.12 KKA02009.1 - 5.1e-39 133.6 0.0 9.3e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone RACo_C_ter PF14574.6 KKA02009.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Syntaxin PF00804.25 KKA02010.1 - 1.1e-22 80.7 22.8 1.1e-22 80.7 22.8 1.9 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KKA02010.1 - 2e-12 46.9 1.7 2e-12 46.9 1.7 2.8 2 0 0 2 2 2 1 SNARE domain ATP-synt_E_2 PF08112.11 KKA02010.1 - 0.066 13.5 4.0 0.17 12.2 4.0 1.8 1 0 0 1 1 1 0 ATP synthase epsilon subunit LMBR1 PF04791.16 KKA02010.1 - 0.087 11.7 10.5 0.14 11.1 10.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein YtxH PF12732.7 KKA02010.1 - 0.22 12.1 3.4 1.2 9.8 0.8 2.7 2 1 0 2 2 2 0 YtxH-like protein DUF745 PF05335.13 KKA02010.1 - 1.3 8.7 24.8 0.12 12.0 6.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Allexi_40kDa PF05549.11 KKA02010.1 - 1.6 8.2 16.9 0.15 11.5 7.0 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 KKA02010.1 - 2 8.5 18.4 6 6.9 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 KKA02010.1 - 2.3 8.1 19.1 0.075 12.8 4.1 3.4 2 2 0 2 2 2 0 Synaptobrevin T2SSF PF00482.23 KKA02010.1 - 4.1 7.4 7.0 0.68 9.9 1.6 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F ACCA PF03255.14 KKA02010.1 - 4.7 7.1 14.1 1.5 8.7 0.4 3.0 2 1 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2203 PF09969.9 KKA02010.1 - 6.2 7.6 15.6 11 6.8 1.6 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) HisKA_3 PF07730.13 KKA02010.1 - 7.9 7.1 9.1 2.1 8.9 0.8 3.3 2 2 0 2 2 2 0 Histidine kinase Syntaxin_2 PF14523.6 KKA02010.1 - 9.8 6.6 26.9 1.1 9.7 17.0 2.8 1 1 2 3 3 3 0 Syntaxin-like protein Fas_alpha_ACP PF18325.1 KKA02011.1 - 3.2e-72 242.2 0.0 7.1e-72 241.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KKA02011.1 - 1.4e-70 237.1 1.3 1.4e-70 237.1 1.3 2.2 3 0 0 3 3 3 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KKA02011.1 - 5.7e-22 78.5 0.1 1.4e-21 77.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KKA02011.1 - 1.3e-14 54.3 0.1 5.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KKA02011.1 - 1.4e-13 50.9 0.0 3.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KKA02011.1 - 0.04 13.3 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Armet PF10208.9 KKA02011.1 - 0.085 12.8 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding AdoHcyase_NAD PF00670.21 KKA02011.1 - 0.094 12.8 1.8 0.6 10.2 0.7 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 KKA02011.1 - 0.11 13.1 0.0 0.59 10.8 0.0 2.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1451 PF07295.11 KKA02011.1 - 0.53 10.3 12.3 0.69 9.9 0.7 3.7 3 0 0 3 3 3 0 Zinc-ribbon containing domain DUF3597 PF12200.8 KKA02011.1 - 1.3 9.5 5.3 5.6 7.5 5.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) mRNA_triPase PF02940.15 KKA02012.1 - 7.4e-50 169.7 3.5 7.4e-50 169.7 3.5 2.2 2 1 0 2 2 2 1 mRNA capping enzyme, beta chain RIBIOP_C PF04950.12 KKA02013.1 - 7.7e-87 291.4 1.5 7.7e-87 291.4 1.5 3.1 4 1 1 5 5 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKA02013.1 - 4.3e-20 71.6 0.0 2.6e-19 69.1 0.0 2.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KKA02013.1 - 4.6e-05 23.1 0.2 0.0013 18.3 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKA02013.1 - 6.8e-05 23.2 0.1 0.00032 21.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KKA02013.1 - 0.00067 18.9 0.1 0.087 12.0 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain Pox_A32 PF04665.12 KKA02013.1 - 0.0029 17.1 0.0 0.0072 15.8 0.0 1.7 1 0 0 1 1 1 1 Poxvirus A32 protein PduV-EutP PF10662.9 KKA02013.1 - 0.01 15.6 1.2 0.081 12.7 1.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KKA02013.1 - 0.012 15.8 0.0 0.046 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKA02013.1 - 0.012 15.9 0.0 0.057 13.8 0.0 2.3 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KKA02013.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 KKA02013.1 - 0.022 14.6 0.1 0.057 13.3 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KKA02013.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKA02013.1 - 0.056 13.5 0.0 0.056 13.5 0.0 4.2 3 1 1 4 4 4 0 AAA domain AAA PF00004.29 KKA02013.1 - 0.056 13.9 0.1 0.21 12.0 0.1 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KKA02013.1 - 0.067 12.8 0.1 0.2 11.2 0.1 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KKA02013.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.6 3 1 1 4 4 3 0 ABC transporter Arf PF00025.21 KKA02014.1 - 2.4e-58 196.5 0.0 2.7e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKA02014.1 - 9.7e-09 34.8 0.3 1.2e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKA02014.1 - 1.5e-06 27.9 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKA02014.1 - 1.7e-06 27.6 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKA02014.1 - 2e-05 24.7 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KKA02014.1 - 6e-05 23.3 0.0 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KKA02014.1 - 0.014 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KKA02014.1 - 0.16 11.7 0.1 0.47 10.2 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cyclin PF08613.11 KKA02015.1 - 0.0012 19.3 5.3 0.0015 19.0 1.7 2.3 1 1 0 2 2 2 1 Cyclin Ntox23 PF15528.6 KKA02015.1 - 0.034 14.3 0.3 0.11 12.7 0.3 1.9 1 0 0 1 1 1 0 Bacterial toxin 23 ATP-cone PF03477.16 KKA02015.1 - 0.072 13.7 0.5 0.32 11.6 0.2 2.3 2 0 0 2 2 2 0 ATP cone domain Ribosomal_L1 PF00687.21 KKA02016.1 - 8e-42 143.3 0.9 1e-41 143.0 0.7 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family FtsJ PF01728.19 KKA02017.1 - 2.3e-49 167.9 0.1 2.9e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KKA02017.1 - 0.0001 22.2 0.9 0.0014 18.5 0.5 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA02017.1 - 0.00049 20.0 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA02017.1 - 0.12 13.1 0.1 0.34 11.6 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Coatomer_WDAD PF04053.14 KKA02018.1 - 1.5e-125 419.8 7.8 1.7e-125 419.5 5.6 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KKA02018.1 - 1.3e-29 101.8 8.0 0.00012 22.8 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA02018.1 - 3e-08 33.8 0.1 0.13 12.6 0.0 6.5 3 3 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKA02018.1 - 0.0066 15.1 5.7 0.18 10.4 0.1 3.5 3 1 0 4 4 4 2 Nucleoporin Nup120/160 PQQ PF01011.21 KKA02018.1 - 0.041 13.8 1.0 25 5.0 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat tRNA_Me_trans PF03054.16 KKA02018.1 - 0.056 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase DUF3575 PF12099.8 KKA02018.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) Clathrin PF00637.20 KKA02018.1 - 0.12 12.2 1.7 3.1 7.7 0.1 2.4 1 1 0 2 2 2 0 Region in Clathrin and VPS DUF1357 PF07094.11 KKA02019.1 - 0.0063 16.6 0.8 0.014 15.5 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1357) TRP PF06011.12 KKA02020.1 - 1.3e-141 472.2 38.2 1.9e-141 471.7 38.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKA02020.1 - 1.2e-38 132.6 0.1 2e-38 131.9 0.1 1.4 1 0 0 1 1 1 1 ML-like domain ETF_QO PF05187.13 KKA02023.1 - 1e-44 150.9 1.0 1.8e-44 150.1 1.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 KKA02023.1 - 6e-12 45.3 0.0 7.6e-07 28.5 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKA02023.1 - 1.1e-10 41.7 0.0 1.7e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KKA02023.1 - 8.1e-10 38.3 0.0 2.1e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KKA02023.1 - 3.6e-07 30.3 0.0 8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKA02023.1 - 1.6e-06 27.6 0.0 3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKA02023.1 - 1.9e-06 26.8 0.1 3.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KKA02023.1 - 0.00016 21.1 0.1 0.00039 19.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KKA02023.1 - 0.00016 20.9 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KKA02023.1 - 0.00023 20.7 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KKA02023.1 - 0.00024 20.6 0.0 0.6 9.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_3 PF13738.6 KKA02023.1 - 0.001 18.4 0.1 0.0021 17.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKA02023.1 - 0.0066 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KKA02023.1 - 0.0091 16.0 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_9 PF13187.6 KKA02023.1 - 0.013 15.6 0.6 0.026 14.7 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKA02023.1 - 0.023 14.8 0.7 0.05 13.7 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 KKA02023.1 - 0.048 12.5 0.3 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 KKA02023.1 - 0.062 12.6 0.2 1.3 8.2 0.0 2.8 3 1 0 4 4 4 0 Flavin containing amine oxidoreductase Fer4_2 PF12797.7 KKA02023.1 - 0.22 11.7 0.7 0.56 10.4 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain CDC24 PF06395.11 KKA02024.1 - 2.8e-33 114.0 2.0 5.5e-33 113.1 0.6 2.4 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 KKA02024.1 - 4.1e-26 92.3 8.3 4.1e-26 92.3 8.3 2.7 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 KKA02024.1 - 7.3e-18 65.0 1.9 3.3e-17 62.9 1.9 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 KKA02024.1 - 3.1e-05 23.8 0.4 0.0001 22.1 0.4 1.9 1 0 0 1 1 1 1 PB1 domain COPIIcoated_ERV PF07970.12 KKA02025.1 - 1.2e-39 136.5 0.4 1.6e-39 136.0 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KKA02025.1 - 6.2e-25 87.4 0.6 1.3e-24 86.3 0.6 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.24 KKA02026.1 - 9.5e-19 67.5 2.2 1.3e-18 67.1 0.9 1.8 1 1 0 2 2 2 1 PX domain CBFD_NFYB_HMF PF00808.23 KKA02027.1 - 2.7e-19 69.2 1.2 4.9e-19 68.4 1.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKA02027.1 - 3.3e-12 46.9 1.6 4.7e-12 46.4 1.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KKA02027.1 - 0.00017 21.6 0.3 0.00038 20.5 0.3 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Mg_chelatase_C PF13335.6 KKA02027.1 - 0.031 14.9 0.1 0.071 13.7 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal CENP-X PF09415.10 KKA02027.1 - 0.043 14.1 1.3 0.072 13.4 0.1 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF3453 PF11935.8 KKA02028.1 - 2.1e-07 30.8 0.8 1.5e-06 28.0 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) SAM_2 PF07647.17 KKA02029.1 - 1.9e-08 34.3 0.6 5.4e-08 32.8 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKA02029.1 - 2e-06 28.1 0.2 4.9e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.19 KKA02030.1 - 1.6e-36 126.2 7.9 3.6e-36 125.1 7.9 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase eIF2A PF08662.11 KKA02031.1 - 4.4e-13 49.5 2.6 6e-07 29.5 0.3 3.9 3 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KKA02031.1 - 3.7e-12 45.9 0.4 1.5e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKA02031.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ANAPC4_WD40 PF12894.7 KKA02031.1 - 0.071 13.4 0.1 7.1 7.0 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Lipocalin_3 PF12702.7 KKA02031.1 - 0.092 12.8 0.2 0.35 11.0 0.2 2.0 1 0 0 1 1 1 0 Lipocalin-like Zn_clus PF00172.18 KKA02032.1 - 0.0001 22.4 16.0 0.00022 21.3 16.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KKA02033.1 - 2.6e-05 24.2 11.3 5.2e-05 23.3 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KKA02034.1 - 1.4e-254 845.9 16.6 1.6e-254 845.7 16.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKA02034.1 - 9.5e-14 50.9 6.2 7.1e-12 44.8 2.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KKA02034.1 - 0.00018 21.3 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KKA02034.1 - 0.016 14.7 0.2 6.5 6.2 0.2 2.8 2 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KKA02034.1 - 0.12 12.8 12.8 0.49 10.8 1.1 4.2 3 2 0 3 3 3 0 Cell division protein FtsA Peptidase_M22 PF00814.25 KKA02035.1 - 5.1e-81 272.3 0.0 6.7e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KKA02035.1 - 0.029 14.0 0.1 0.093 12.4 0.0 1.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SMC_N PF02463.19 KKA02036.1 - 2.1e-24 86.2 72.3 2.5e-21 76.1 72.3 4.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKA02036.1 - 4.3e-24 85.1 0.0 1.2e-23 83.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKA02036.1 - 6.9e-16 58.9 5.0 2.6e-10 40.6 1.2 4.0 3 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKA02036.1 - 4.8e-09 36.4 37.6 4.8e-09 36.4 37.6 4.3 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KKA02036.1 - 0.001 18.8 0.1 0.0023 17.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KKA02036.1 - 0.0037 17.8 52.3 0.0037 17.8 52.3 7.0 3 2 2 5 5 5 1 AAA domain DEAD PF00270.29 KKA02036.1 - 0.0073 16.1 5.4 1.9 8.2 0.0 4.0 4 1 0 4 4 4 2 DEAD/DEAH box helicase Cytokin_check_N PF10407.9 KKA02037.1 - 9.6e-12 44.7 0.7 3.3e-11 43.0 0.7 1.9 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Sld5 PF05916.11 KKA02038.1 - 2.6e-20 72.9 1.4 2.6e-20 72.9 1.4 1.9 2 0 0 2 2 2 1 GINS complex protein Snurportin1 PF11538.8 KKA02038.1 - 5.6 7.2 8.9 16 5.8 8.9 1.7 1 0 0 1 1 1 0 Snurportin1 Peptidase_M28 PF04389.17 KKA02039.1 - 3e-37 128.3 0.2 4.4e-37 127.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKA02039.1 - 1.6e-11 44.0 0.1 4.5e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KKA02039.1 - 2.4e-05 24.1 0.0 7.3e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KKA02039.1 - 0.075 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase AA_permease_2 PF13520.6 KKA02040.1 - 5.6e-54 183.6 48.9 8e-54 183.1 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1151 PF06625.11 KKA02041.1 - 0.14 12.1 6.5 0.58 10.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Tox-REase-2 PF15646.6 KKA02041.1 - 0.31 11.2 2.6 0.4 10.8 1.5 1.7 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 GATA PF00320.27 KKA02042.1 - 5.2e-16 58.0 2.5 9.2e-16 57.2 2.5 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF2387 PF09526.10 KKA02042.1 - 0.0027 17.8 0.0 0.0091 16.1 0.0 1.9 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.17 KKA02042.1 - 0.009 15.9 0.5 0.023 14.6 0.5 1.7 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KKA02042.1 - 0.019 14.5 0.3 0.04 13.4 0.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 KKA02042.1 - 0.2 11.9 0.4 0.4 10.9 0.4 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pam16 PF03656.13 KKA02043.1 - 3.3e-29 101.5 0.9 4.5e-29 101.1 0.2 1.5 1 1 1 2 2 2 1 Pam16 zf-C2HC5 PF06221.13 KKA02044.1 - 2.4e-14 53.1 4.9 3.9e-14 52.4 4.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DEAD PF00270.29 KKA02045.1 - 3.7e-39 134.3 0.0 6.9e-39 133.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02045.1 - 7.8e-18 64.8 0.0 7.4e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKA02045.1 - 4e-17 62.2 0.1 1.3e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKA02045.1 - 3.3e-07 30.5 0.0 3.3e-07 30.5 0.0 3.1 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit RHH_7 PF16777.5 KKA02045.1 - 9.5 6.7 10.5 1.9 8.9 1.4 3.7 3 0 0 3 3 3 0 Transcriptional regulator, RHH-like, CopG Sin_N PF04801.13 KKA02046.1 - 4.3e-09 36.1 4.6 6.5e-09 35.5 4.6 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region Hyaluronidase_1 PF07212.11 KKA02046.1 - 0.001 18.4 0.6 0.0017 17.7 0.6 1.3 1 0 0 1 1 1 1 Hyaluronidase protein (HylP) SLS PF14611.6 KKA02046.1 - 0.031 14.1 1.7 0.12 12.2 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator YcaO_C PF18381.1 KKA02046.1 - 0.087 12.7 0.1 1 9.3 0.0 2.5 3 0 0 3 3 3 0 YcaO cyclodehydratase C-terminal domain CEL_III_C PF18054.1 KKA02046.1 - 0.82 9.7 6.7 1 9.4 0.1 3.0 1 1 2 3 3 3 0 CEL-III C-terminal IF-2B PF01008.17 KKA02047.1 - 1.2e-63 215.0 0.0 1.5e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PHD PF00628.29 KKA02048.1 - 6.2e-07 29.2 6.3 6.2e-07 29.2 6.3 3.1 4 0 0 4 4 4 1 PHD-finger SET PF00856.28 KKA02048.1 - 0.00013 22.4 9.1 0.00013 22.4 9.1 4.6 2 2 0 2 2 2 1 SET domain PHD_2 PF13831.6 KKA02048.1 - 0.0003 20.3 6.2 0.00076 19.0 6.2 1.7 1 0 0 1 1 1 1 PHD-finger Ribosomal_60s PF00428.19 KKA02048.1 - 0.44 11.2 13.8 0.11 13.1 1.9 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF5439 PF17507.2 KKA02049.1 - 0.05 13.8 1.0 12 6.2 0.0 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5439) BP28CT PF08146.12 KKA02050.1 - 3.9e-30 104.8 6.9 3.9e-30 104.8 6.9 3.5 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KKA02050.1 - 3.4e-10 40.3 1.8 3.4e-10 40.3 1.8 6.2 7 2 1 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KKA02050.1 - 0.0002 21.7 0.1 0.29 11.5 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KKA02050.1 - 0.0043 17.5 0.0 0.57 10.7 0.0 3.7 2 0 0 2 2 2 1 HEAT-like repeat Sugar_tr PF00083.24 KKA02050.1 - 0.019 13.8 0.6 0.088 11.6 0.0 2.1 2 0 0 2 2 2 0 Sugar (and other) transporter HEAT PF02985.22 KKA02050.1 - 0.025 14.8 1.4 0.39 11.1 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Cyclin_C PF02984.19 KKA02050.1 - 0.16 12.0 4.3 0.38 10.9 0.0 3.6 3 0 0 3 3 3 0 Cyclin, C-terminal domain DSPn PF14671.6 KKA02051.1 - 2.3e-48 164.2 0.2 6.2e-46 156.4 0.2 2.7 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KKA02051.1 - 3.5e-16 59.2 0.0 3.1e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKA02051.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKA02051.1 - 0.0082 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 KKA02051.1 - 0.033 13.9 0.8 0.075 12.7 0.0 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Alb1 PF09135.11 KKA02054.1 - 2.8e-14 53.9 17.9 2.8e-14 53.9 17.9 2.0 2 1 0 2 2 2 1 Alb1 Nup188_C PF18378.1 KKA02054.1 - 0.011 14.5 2.5 0.017 13.9 2.5 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain YpjP PF14005.6 KKA02054.1 - 0.17 12.0 8.7 0.098 12.7 6.2 1.8 1 1 1 2 2 2 0 YpjP-like protein Prismane PF03063.20 KKA02054.1 - 0.26 9.9 3.6 0.33 9.6 3.6 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family LRR_4 PF12799.7 KKA02055.1 - 6.8e-05 23.1 2.4 6.8e-05 23.1 2.4 7.4 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKA02055.1 - 0.0041 16.9 12.3 0.0041 16.9 12.3 6.0 3 1 2 6 6 6 2 Leucine rich repeat DnaB PF00772.21 KKA02055.1 - 0.045 13.8 0.0 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain LRR_6 PF13516.6 KKA02055.1 - 0.28 11.4 14.6 1.7 8.9 1.8 5.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KKA02055.1 - 0.28 11.9 19.2 2.2 9.2 1.5 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat DSPc PF00782.20 KKA02056.1 - 8e-26 90.4 0.4 4.5e-18 65.4 0.2 3.3 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKA02056.1 - 1.6e-05 24.6 0.1 7.3e-05 22.4 0.0 2.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KKA02056.1 - 0.0011 18.7 0.2 0.054 13.2 0.0 2.8 3 0 0 3 3 3 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Ribosomal_L17 PF01196.19 KKA02057.1 - 0.00017 22.4 1.4 0.00029 21.7 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 KKA02057.1 - 0.073 13.4 7.2 0.024 14.9 3.9 2.0 2 1 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain adh_short PF00106.25 KKA02058.1 - 7.3e-15 54.9 0.0 3e-14 52.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKA02058.1 - 2.5e-11 43.8 0.0 3.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain VirE_N PF08800.10 KKA02058.1 - 0.012 15.8 0.0 0.026 14.6 0.0 1.7 1 1 1 2 2 2 0 VirE N-terminal domain Polysacc_synt_2 PF02719.15 KKA02058.1 - 0.082 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SBF PF01758.16 KKA02058.1 - 0.11 12.2 0.6 0.17 11.6 0.6 1.3 1 0 0 1 1 1 0 Sodium Bile acid symporter family zf-C2H2_2 PF12756.7 KKA02059.1 - 2.5e-28 98.4 15.4 6.4e-28 97.0 4.4 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-P11 PF03854.14 KKA02059.1 - 1.1 9.0 4.1 8 6.2 0.5 2.5 2 0 0 2 2 2 0 P-11 zinc finger MMADHC PF10229.9 KKA02059.1 - 1.2 8.8 6.7 1.1 8.9 0.1 2.8 3 1 0 3 3 3 0 Methylmalonic aciduria and homocystinuria type D protein Phosphodiest PF01663.22 KKA02060.1 - 1.9e-13 50.8 2.4 1.5e-08 34.6 0.3 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKA02060.1 - 0.018 14.5 0.0 0.096 12.1 0.0 2.0 2 0 0 2 2 2 0 Sulfatase Ribosomal_L37 PF08561.10 KKA02061.1 - 1.4e-15 57.8 4.3 7.1e-15 55.6 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Nucleoporin_FG PF13634.6 KKA02062.1 - 7.9e-17 61.9 41.6 1.6e-08 35.3 3.5 6.0 1 1 5 6 6 6 5 Nucleoporin FG repeat region Tcp10_C PF07202.13 KKA02062.1 - 0.66 9.9 3.5 0.62 10.0 0.4 2.2 2 0 0 2 2 2 0 T-complex protein 10 C-terminus Spc7 PF08317.11 KKA02063.1 - 0.00036 19.5 8.0 0.00045 19.2 8.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CREPT PF16566.5 KKA02063.1 - 0.017 15.3 4.3 0.037 14.2 0.5 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF948 PF06103.11 KKA02063.1 - 0.085 13.1 1.8 0.19 12.0 0.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AI-2E_transport PF01594.16 KKA02063.1 - 0.19 10.9 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 AI-2E family transporter Helo_like_N PF17111.5 KKA02063.1 - 0.27 10.6 6.7 0.14 11.5 1.2 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF496 PF04363.12 KKA02063.1 - 0.74 9.9 11.7 0.12 12.4 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF496) DUF1674 PF07896.12 KKA02064.1 - 2.3e-20 72.8 0.6 5.6e-20 71.6 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_1_2 PF00155.21 KKA02065.1 - 2.2e-64 217.9 0.0 2.6e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKA02065.1 - 0.0019 17.2 0.6 0.014 14.3 0.6 2.0 1 1 1 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KKA02065.1 - 0.0063 15.1 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKA02065.1 - 0.019 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKA02065.1 - 0.055 12.8 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Endopep_inhib PF16800.5 KKA02065.1 - 0.17 11.9 8.1 0.91 9.5 0.3 3.2 3 0 0 3 3 3 0 IseA DL-endopeptidase inhibitor HSM3_C PF18794.1 KKA02066.1 - 1.5e-12 47.5 4.8 1.5e-12 47.5 4.8 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein HSM3, C terminal domain Spore_YabQ PF09578.10 KKA02067.1 - 0.26 11.5 1.5 2.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Vps26 PF03643.15 KKA02068.1 - 1.9e-88 296.1 0.9 2.2e-88 295.9 0.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Imm19 PF15563.6 KKA02068.1 - 0.0026 17.3 1.7 0.0044 16.5 1.7 1.3 1 0 0 1 1 1 1 Immunity protein 19 Rgp1 PF08737.10 KKA02068.1 - 0.0036 16.6 0.4 1 8.4 0.0 2.6 3 0 0 3 3 3 2 Rgp1 Arrestin_C PF02752.22 KKA02068.1 - 0.034 14.6 4.3 0.073 13.5 0.1 2.9 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Tim54 PF11711.8 KKA02069.1 - 7.8e-78 261.9 0.7 6.9e-77 258.7 0.7 1.9 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PBP_like_2 PF12849.7 KKA02069.1 - 0.062 13.0 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain DUF4748 PF15932.5 KKA02069.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Myb_DNA-binding PF00249.31 KKA02070.1 - 2.2e-19 69.4 1.0 7.5e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA02070.1 - 3.1e-15 56.1 2.9 9e-12 45.1 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain NAT PF04768.13 KKA02071.1 - 2.5e-39 134.7 1.9 4e-39 134.0 0.1 2.2 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF4806 PF16064.5 KKA02071.1 - 1.4 9.3 4.8 12 6.2 0.1 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF4806) DUF3336 PF11815.8 KKA02072.1 - 5.7e-19 68.2 0.8 5.7e-19 68.2 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKA02072.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase UBX PF00789.20 KKA02073.1 - 2.4e-13 50.1 1.9 2.9e-13 49.8 0.5 1.9 2 0 0 2 2 2 1 UBX domain Amidase_3 PF01520.18 KKA02073.1 - 8.1e-05 22.8 2.3 0.00041 20.5 2.3 2.2 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Spike_torovirin PF17072.5 KKA02073.1 - 0.16 9.1 0.1 0.21 8.7 0.1 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Pkinase PF00069.25 KKA02074.1 - 5e-53 180.2 0.0 7.9e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02074.1 - 8.7e-25 87.5 0.0 1.3e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA02074.1 - 0.00022 20.3 0.1 0.00063 18.8 0.1 1.8 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKA02074.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKA02074.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NAF PF03822.14 KKA02074.1 - 0.033 14.4 0.1 0.087 13.0 0.1 1.8 1 0 0 1 1 1 0 NAF domain Kdo PF06293.14 KKA02074.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SHMT PF00464.19 KKA02075.1 - 7.5e-184 610.9 0.0 9.1e-184 610.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KKA02076.1 - 4.6e-17 62.2 0.4 1.2e-16 60.9 0.4 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II zf-C2H2_4 PF13894.6 KKA02077.1 - 3.5e-08 33.6 27.9 0.0016 19.1 2.3 5.6 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 KKA02077.1 - 1.9e-06 28.4 50.1 0.0023 18.5 1.8 7.4 4 2 3 7 7 7 4 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KKA02077.1 - 0.0041 17.1 0.7 0.0041 17.1 0.7 5.3 6 0 0 6 6 6 1 C2H2-type zinc finger zf-met PF12874.7 KKA02077.1 - 0.012 16.0 17.5 0.52 10.8 0.0 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KKA02077.1 - 0.019 15.4 2.8 0.019 15.4 2.8 6.2 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KKA02077.1 - 0.046 14.0 28.0 0.25 11.7 0.2 5.4 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KKA02077.1 - 0.054 13.8 11.0 0.33 11.3 4.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon Nmad4 PF18756.1 KKA02077.1 - 0.087 13.2 0.4 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 Nucleotide modification associated domain 4 zf-H2C2_2 PF13465.6 KKA02077.1 - 0.097 13.1 0.4 0.097 13.1 0.4 5.6 5 0 0 5 5 5 0 Zinc-finger double domain Methyltransf_16 PF10294.9 KKA02078.1 - 4.6e-24 85.1 0.0 6.7e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KKA02078.1 - 3.7e-08 33.4 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA02078.1 - 0.00088 20.0 0.0 0.0025 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain LepB_N PF18640.1 KKA02078.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 LepB N-terminal domain HbrB PF08539.11 KKA02079.1 - 0.00097 19.2 4.6 0.0084 16.1 0.8 3.4 2 1 0 2 2 2 1 HbrB-like DAG_kinase_N PF14513.6 KKA02079.1 - 0.013 15.7 4.2 0.013 15.7 4.2 3.4 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus CLN3 PF02487.17 KKA02080.1 - 7.2e-111 371.0 26.7 7.3e-66 222.9 4.8 2.0 1 1 1 2 2 2 2 CLN3 protein AA_permease_2 PF13520.6 KKA02081.1 - 2.3e-48 165.1 43.7 2.9e-48 164.8 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4181 PF13789.6 KKA02081.1 - 3.1 8.1 7.0 1.4 9.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) PLDc PF00614.22 KKA02082.1 - 5.5e-16 58.0 2.6 7.3e-07 29.1 0.0 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KKA02082.1 - 4.2e-13 49.3 1.0 1.1e-08 35.1 0.0 3.8 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 KKA02082.1 - 0.0001 22.3 10.7 0.0009 19.2 0.8 4.8 5 0 0 5 5 5 2 PX domain PH PF00169.29 KKA02082.1 - 0.00052 20.5 0.5 0.0026 18.3 0.5 2.3 1 0 0 1 1 1 1 PH domain SNARE PF05739.19 KKA02083.1 - 2.3e-06 27.5 0.5 2.3e-06 27.5 0.5 2.2 3 0 0 3 3 3 1 SNARE domain TMEM107 PF14995.6 KKA02083.1 - 0.27 11.7 1.4 0.43 11.0 0.2 2.0 2 1 0 2 2 2 0 Transmembrane protein SUR7 PF06687.12 KKA02084.1 - 1.8e-17 63.7 13.3 1.3e-16 60.9 13.5 2.2 1 1 0 1 1 1 1 SUR7/PalI family Extensin_1 PF02095.15 KKA02084.1 - 3.5 8.1 5.8 7.8 7.0 5.8 1.6 1 0 0 1 1 1 0 Extensin-like protein repeat AA_permease PF00324.21 KKA02085.1 - 1.3e-128 429.7 34.6 1.6e-128 429.4 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02085.1 - 5.8e-32 111.1 35.8 7.7e-32 110.6 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF5010_C PF18099.1 KKA02085.1 - 0.097 12.8 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 DUF5010 C-terminal domain DUF4231 PF14015.6 KKA02085.1 - 1.3 9.5 7.5 11 6.5 0.9 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) BRCT PF00533.26 KKA02086.1 - 9.9e-06 25.9 8.8 0.0072 16.7 0.2 4.1 4 1 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKA02086.1 - 3.3e-05 23.8 0.1 0.0027 17.6 0.1 2.8 2 0 0 2 2 2 1 twin BRCT domain DUF2023 PF09633.10 KKA02086.1 - 0.041 14.0 0.6 2 8.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2023) Pico_P2B PF01552.17 KKA02086.1 - 0.096 12.8 0.5 0.87 9.8 0.7 2.5 2 0 0 2 2 2 0 Picornavirus 2B protein ANAPC4_WD40 PF12894.7 KKA02087.1 - 2.7e-08 34.0 1.2 0.086 13.1 0.1 5.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKA02087.1 - 3.9e-07 30.7 0.1 0.32 11.9 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat COPI_C PF06957.11 KKA02087.1 - 4 6.1 10.0 6.5 5.4 10.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus MRP-L27 PF09809.9 KKA02088.1 - 2.6e-09 36.9 0.1 3.3e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DEAD PF00270.29 KKA02089.1 - 2.9e-43 147.7 0.1 4.2e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02089.1 - 2e-29 102.1 0.9 6.1e-29 100.6 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02089.1 - 3.5e-06 27.1 0.0 8.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKA02089.1 - 0.00026 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KKA02089.1 - 0.022 15.0 0.3 0.051 13.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain AA_permease PF00324.21 KKA02090.1 - 8.1e-135 450.1 27.6 9.3e-135 449.9 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02090.1 - 7e-35 120.7 28.4 9.7e-35 120.2 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sel1 PF08238.12 KKA02091.1 - 7.2e-06 26.5 7.1 0.00016 22.2 3.8 4.1 4 0 0 4 4 4 1 Sel1 repeat TPR_7 PF13176.6 KKA02091.1 - 0.011 15.7 1.4 0.036 14.1 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKA02091.1 - 2.7 8.5 5.0 79 3.8 4.7 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 KKA02092.1 - 2.2e-21 75.8 20.0 0.00054 20.7 0.5 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA02092.1 - 1.4e-05 25.3 2.8 0.91 9.9 0.0 4.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KKA02092.1 - 0.056 13.4 2.0 0.055 13.4 0.7 1.7 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KKA02092.1 - 0.14 11.1 5.8 0.85 8.5 0.2 3.3 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_UDP_1 PF01048.20 KKA02093.1 - 5e-39 133.9 0.0 6.1e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ENTH PF01417.20 KKA02094.1 - 1.5e-30 105.8 0.3 1.5e-30 105.8 0.3 2.1 2 0 0 2 2 2 1 ENTH domain DUF1720 PF08226.11 KKA02094.1 - 0.013 15.9 8.7 0.013 15.9 8.7 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1720) LMBR1 PF04791.16 KKA02094.1 - 7.5 5.3 13.2 10 4.9 13.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_ligase_A_M PF01068.21 KKA02095.1 - 6.9e-59 198.9 2.1 1.2e-58 198.1 2.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKA02095.1 - 1.8e-29 103.3 0.6 3e-29 102.6 0.6 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKA02095.1 - 1.4e-21 76.9 0.0 2.9e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKA02095.1 - 1.2e-07 32.2 0.6 2.6e-07 31.1 0.6 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KKA02095.1 - 0.16 12.0 0.4 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain zf-Mss51 PF13824.6 KKA02096.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 KKA02096.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Scm3 PF10384.9 KKA02096.1 - 0.068 12.9 0.3 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 Centromere protein Scm3 OCRE PF17780.1 KKA02096.1 - 0.18 11.9 2.7 2.3 8.3 0.1 2.9 3 0 0 3 3 3 0 OCRE domain NOT2_3_5 PF04153.18 KKA02097.1 - 2.5e-25 89.1 4.2 3.9e-25 88.4 4.2 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ADH_N PF08240.12 KKA02098.1 - 1.2e-19 70.2 4.3 1.9e-19 69.5 4.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKA02098.1 - 1.1e-13 51.3 0.0 1.8e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKA02098.1 - 0.0023 17.3 0.1 0.0038 16.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKA02098.1 - 0.0035 16.7 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KKA02098.1 - 0.0091 17.0 0.0 0.015 16.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.16 KKA02098.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ETF PF01012.21 KKA02098.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Shikimate_DH PF01488.20 KKA02098.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KKA02098.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MARVEL PF01284.23 KKA02099.1 - 9.5e-29 100.3 14.2 1.1e-28 100.0 14.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Scaffolding_pro PF11418.8 KKA02100.1 - 0.067 13.8 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 Phi29 scaffolding protein Proteasome PF00227.26 KKA02103.1 - 2e-54 184.0 0.1 2.9e-54 183.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKA02103.1 - 5.8e-12 45.1 0.9 8.9e-12 44.5 0.2 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SH3_1 PF00018.28 KKA02104.1 - 2.2e-13 49.5 0.0 3.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKA02104.1 - 6.9e-12 45.0 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKA02104.1 - 3.6e-07 29.8 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF3292 PF11696.8 KKA02104.1 - 0.094 11.1 1.1 0.12 10.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Presenilin PF01080.17 KKA02104.1 - 0.13 11.1 2.1 0.2 10.4 2.1 1.3 1 0 0 1 1 1 0 Presenilin GCR1_C PF12550.8 KKA02105.1 - 0.00065 20.0 0.1 0.0031 17.8 0.1 2.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF4595 PF15283.6 KKA02105.1 - 0.21 11.7 5.0 0.075 13.1 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4595) with porin-like fold MFS_1 PF07690.16 KKA02106.1 - 5.4e-25 88.1 24.3 5.4e-25 88.1 24.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA02106.1 - 4.6e-09 35.6 18.6 4.6e-09 35.6 18.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Vps62 PF06101.11 KKA02107.1 - 1.2e-07 30.5 7.7 1.8e-07 29.9 1.4 2.5 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 62 SIS PF01380.22 KKA02108.1 - 0.0027 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 SIS domain Methyltransf_8 PF05148.15 KKA02108.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.5 1 1 1 2 2 2 1 Hypothetical methyltransferase SKN1 PF03935.15 KKA02109.1 - 8.4e-246 816.2 11.8 8.4e-246 816.2 11.8 1.5 2 0 0 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) Consortin_C PF15281.6 KKA02109.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus MCM PF00493.23 KKA02110.1 - 1.7e-101 338.0 0.6 1.7e-101 338.0 0.6 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KKA02110.1 - 1.3e-36 125.2 0.0 2.3e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKA02110.1 - 4.5e-25 87.9 1.6 4.5e-25 87.9 1.6 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 KKA02110.1 - 1.6e-18 66.9 0.9 5.3e-18 65.2 0.9 2.0 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KKA02110.1 - 7.6e-15 55.4 2.0 4.8e-14 52.8 2.0 2.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKA02110.1 - 1.3e-07 31.3 0.0 4.8e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KKA02110.1 - 0.0022 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KKA02110.1 - 0.0099 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKA02110.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tim44 PF04280.15 KKA02111.1 - 1e-30 106.8 0.1 3.2e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain DUF730 PF05325.11 KKA02111.1 - 0.018 15.0 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Ndc1_Nup PF09531.10 KKA02111.1 - 7.2 5.2 7.9 8.7 4.9 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup B-block_TFIIIC PF04182.12 KKA02112.1 - 0.43 10.8 4.3 0.96 9.7 1.1 2.1 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC RNA_pol_A_bac PF01000.26 KKA02113.1 - 1.7e-31 108.9 0.6 5.8e-31 107.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKA02113.1 - 7.4e-17 60.5 0.0 9.9e-17 60.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.21 KKA02114.1 - 2.3e-27 96.0 0.2 2.8e-27 95.7 0.2 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 KKA02114.1 - 0.14 11.6 0.5 4.3 6.7 0.0 2.8 2 1 1 3 3 3 0 PcrB family DUF4602 PF15375.6 KKA02115.1 - 0.016 15.5 10.1 0.016 15.5 10.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4602) HLH PF00010.26 KKA02116.1 - 1.9e-11 43.8 0.8 4.3e-11 42.6 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.9 KKA02116.1 - 0.022 14.9 1.3 0.16 12.2 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) RRM_1 PF00076.22 KKA02117.1 - 2.8e-05 23.9 0.0 0.09 12.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 KKA02118.1 - 1.7e-62 210.7 35.5 1.5e-60 204.4 35.5 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKA02118.1 - 5e-19 68.7 0.5 5e-19 68.7 0.5 2.6 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKA02118.1 - 5.7e-07 29.6 25.0 4.1e-05 23.6 0.3 5.0 3 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKA02118.1 - 4.2e-05 23.2 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KKA02118.1 - 0.00026 20.8 23.6 0.00026 20.8 23.6 5.4 1 1 2 4 4 4 1 AAA ATPase domain Dicty_CAD PF05720.12 KKA02118.1 - 0.29 11.1 1.7 4 7.5 0.1 3.2 3 0 0 3 3 3 0 Cell-cell adhesion domain DUF3800 PF12686.7 KKA02118.1 - 0.49 11.0 16.8 2.7 8.6 1.4 5.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) AAA_27 PF13514.6 KKA02118.1 - 1.1 8.8 0.0 1.1 8.8 0.0 5.4 6 0 0 6 6 6 0 AAA domain BAG PF02179.16 KKA02119.1 - 5.7e-13 49.1 3.1 1.1e-12 48.2 3.1 1.5 1 0 0 1 1 1 1 BAG domain Phage_int_SAM_6 PF18644.1 KKA02119.1 - 0.033 14.2 2.2 0.45 10.5 0.3 2.3 1 1 1 2 2 2 0 Phage integrase SAM-like domain Asp PF00026.23 KKA02120.1 - 5.2e-12 45.8 9.2 2.9e-11 43.4 9.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KKA02120.1 - 8.7e-05 23.1 0.0 0.26 12.0 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKA02120.1 - 0.0036 17.8 0.0 4 8.1 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKA02120.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal WI12 PF07107.11 KKA02120.1 - 0.038 14.1 0.0 0.08 13.1 0.0 1.7 1 1 0 1 1 1 0 Wound-induced protein WI12 Lum_binding PF00677.17 KKA02121.1 - 8e-36 121.9 4.3 3.5e-18 65.4 0.3 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF2314 PF10077.9 KKA02121.1 - 0.098 12.7 0.7 0.39 10.8 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) Cut8 PF08559.10 KKA02122.1 - 5.2e-14 52.4 19.9 1.2e-13 51.2 16.6 2.5 2 1 0 2 2 2 1 Cut8, nuclear proteasome tether protein NPM1-C PF16276.5 KKA02122.1 - 0.058 13.4 0.7 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain EF-hand_12 PF17901.1 KKA02122.1 - 0.066 13.7 0.6 7.4 7.1 0.1 2.7 2 0 0 2 2 2 0 EF-hand fold domain DUF4692 PF15763.5 KKA02123.1 - 3.7 8.0 8.9 13 6.2 8.9 1.9 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sedlin_N PF04628.13 KKA02124.1 - 4.2e-25 88.4 4.7 1.2e-24 86.9 4.7 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KKA02124.1 - 0.00064 19.7 0.2 0.0011 18.9 0.2 1.5 1 0 0 1 1 1 1 Sybindin-like family HMG_CoA_synt_N PF01154.17 KKA02125.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Med22 PF06179.12 KKA02126.1 - 2.5e-07 30.8 9.3 3e-06 27.4 3.8 2.2 2 0 0 2 2 2 2 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.12 KKA02126.1 - 0.00066 20.3 7.8 0.06 14.0 2.6 2.3 2 1 0 2 2 2 2 PMC2NT (NUC016) domain SIN1 PF05422.12 KKA02126.1 - 0.0013 19.3 6.1 0.011 16.3 1.4 2.1 1 1 1 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Peptidase_C101 PF16218.5 KKA02126.1 - 0.029 13.6 2.2 0.048 12.9 2.2 1.4 1 0 0 1 1 1 0 Peptidase family C101 ATPase PF06745.13 KKA02126.1 - 0.04 13.3 1.6 0.058 12.7 1.6 1.3 1 0 0 1 1 1 0 KaiC EMP24_GP25L PF01105.24 KKA02128.1 - 1.4e-36 126.1 0.9 1.7e-36 125.8 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1240 PF06836.12 KKA02128.1 - 0.024 15.2 0.1 0.024 15.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) DUF1761 PF08570.10 KKA02128.1 - 0.025 14.8 0.9 0.044 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) E1-E2_ATPase PF00122.20 KKA02128.1 - 0.034 13.7 0.2 0.066 12.7 0.2 1.4 1 0 0 1 1 1 0 E1-E2 ATPase AhpC-TSA PF00578.21 KKA02129.1 - 7.1e-22 77.6 0.1 1.1e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKA02129.1 - 8.2e-15 54.8 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KKA02129.1 - 0.057 13.5 0.0 0.31 11.2 0.0 2.0 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme Actin PF00022.19 KKA02130.1 - 3.3e-108 361.9 0.0 1.1e-107 360.2 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKA02130.1 - 0.0026 16.6 0.0 0.015 14.2 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Actin_micro PF17003.5 KKA02130.1 - 0.13 11.4 0.9 5.6 6.0 0.1 2.7 3 0 0 3 3 3 0 Putative actin-like family CBF PF03914.17 KKA02132.1 - 2.7e-29 102.4 0.8 6.7e-29 101.1 0.8 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Metallophos PF00149.28 KKA02133.1 - 4.1e-27 96.0 0.8 9.9e-27 94.8 0.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKA02133.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HJURP_C PF12347.8 KKA02133.1 - 0.063 13.3 0.5 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat PPP5 PF08321.12 KKA02133.1 - 0.14 12.4 1.7 0.21 11.9 0.2 2.1 2 1 0 2 2 2 0 PPP5 TPR repeat region P16-Arc PF04699.14 KKA02134.1 - 0.58 10.6 4.0 1.2 9.6 0.6 2.7 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) PhageMin_Tail PF10145.9 KKA02135.1 - 0.24 11.3 2.9 5.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Phage-related minor tail protein ERG2_Sigma1R PF04622.12 KKA02135.1 - 2.7 7.3 6.1 0.67 9.3 2.0 2.2 1 1 0 1 1 1 0 ERG2 and Sigma1 receptor like protein YtxH PF12732.7 KKA02135.1 - 8.9 6.9 23.3 32 5.2 0.3 4.6 1 1 1 2 2 2 0 YtxH-like protein Rrp15p PF07890.12 KKA02136.1 - 9.8e-27 93.9 13.5 9.8e-27 93.9 13.5 2.0 2 0 0 2 2 2 1 Rrp15p RasGAP PF00616.19 KKA02138.1 - 3.6e-19 69.3 2.9 1.6e-16 60.6 1.0 4.4 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase SIN1_PH PF16979.5 KKA02140.1 - 1.9e-08 34.5 3.6 4.1e-05 23.8 0.3 3.3 3 0 0 3 3 3 2 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 KKA02140.1 - 2e-06 28.0 0.1 6.1e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain MMgT PF10270.9 KKA02141.1 - 8.6e-13 48.5 1.6 1.1e-12 48.2 1.6 1.3 1 1 0 1 1 1 1 Membrane magnesium transporter RINGv PF12906.7 KKA02142.1 - 1.7e-11 44.0 3.0 3.9e-11 42.9 3.0 1.6 1 1 0 1 1 1 1 RING-variant domain MFS_1 PF07690.16 KKA02143.1 - 1.1e-16 60.7 15.6 3.8e-09 35.9 2.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA02143.1 - 8e-13 48.0 24.0 9.1e-08 31.4 5.0 3.6 2 1 0 2 2 2 2 Sugar (and other) transporter SafA PF17073.5 KKA02143.1 - 0.022 14.7 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Two-component-system connector protein Peptidase_S10 PF00450.22 KKA02144.1 - 7.9e-92 308.8 4.4 1.3e-91 308.2 4.4 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase BSMAP PF12280.8 KKA02144.1 - 0.00048 20.4 0.1 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 Brain specific membrane anchored protein Orf78 PF06024.12 KKA02144.1 - 0.0022 18.2 0.0 0.0078 16.5 0.0 1.9 1 0 0 1 1 1 1 Orf78 (ac78) SDA1 PF05285.12 KKA02144.1 - 0.005 16.3 11.3 0.0078 15.7 11.3 1.3 1 0 0 1 1 1 1 SDA1 DUF2956 PF11169.8 KKA02144.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF4199 PF13858.6 KKA02144.1 - 0.011 16.1 0.8 0.21 11.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) BUD22 PF09073.10 KKA02144.1 - 0.05 12.9 10.1 0.076 12.3 10.1 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KKA02144.1 - 0.067 11.7 10.4 0.099 11.2 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KKA02144.1 - 0.097 11.0 13.1 0.14 10.4 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KKA02144.1 - 0.12 10.4 26.3 0.067 11.3 23.7 1.7 2 0 0 2 2 2 0 DNA polymerase phi Ndc1_Nup PF09531.10 KKA02144.1 - 0.23 10.1 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RXT2_N PF08595.11 KKA02144.1 - 3.1 7.8 16.4 9.2 6.3 16.4 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3332 PF11810.8 KKA02144.1 - 3.9 7.1 8.4 17 5.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3332) Cwf_Cwc_15 PF04889.12 KKA02144.1 - 5.1 6.8 25.4 9.6 5.9 25.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 KKA02144.1 - 5.3 4.7 7.5 7.4 4.2 7.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 KKA02144.1 - 9.7 5.2 31.6 17 4.4 31.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nrap_D4 PF17405.2 KKA02145.1 - 7.5e-50 169.2 1.2 2.4e-49 167.6 0.1 2.2 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KKA02145.1 - 5.4e-46 156.3 0.1 5.4e-46 156.3 0.1 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KKA02145.1 - 6.1e-42 142.9 6.5 1.1e-40 138.9 0.4 3.0 3 0 0 3 3 3 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KKA02145.1 - 2.2e-33 115.6 0.2 7.2e-33 113.9 0.1 2.0 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 KKA02145.1 - 5.5e-33 114.2 9.1 5.5e-33 114.2 9.1 2.8 3 0 0 3 3 3 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KKA02145.1 - 3.7e-19 69.3 0.6 3.7e-19 69.3 0.6 2.7 3 0 0 3 3 3 1 Nrap protein domain 6 DUF5126 PF17166.4 KKA02146.1 - 0.061 13.2 0.2 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) RAI1 PF08652.11 KKA02147.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Nop PF01798.18 KKA02148.1 - 1.9e-05 24.3 0.1 3.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Pkinase PF00069.25 KKA02149.1 - 2.6e-55 187.6 0.0 1.8e-54 184.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02149.1 - 4e-29 101.7 0.1 1.7e-21 76.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KKA02149.1 - 0.0019 17.6 0.1 0.0045 16.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKA02149.1 - 0.0032 16.5 0.0 0.008 15.2 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKA02149.1 - 0.0043 16.4 0.2 0.018 14.4 0.0 2.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KKA02149.1 - 0.13 12.2 0.0 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4748 PF15932.5 KKA02149.1 - 0.18 11.6 0.1 14 5.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) SUZ PF12752.7 KKA02149.1 - 0.25 12.1 0.1 0.25 12.1 0.1 2.0 2 0 0 2 2 2 0 SUZ domain RNase_H2-Ydr279 PF09468.10 KKA02150.1 - 1e-09 38.8 1.7 1.5e-09 38.2 1.7 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KKA02150.1 - 1e-06 28.9 0.1 2.6e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain Bmt2 PF11968.8 KKA02150.1 - 0.063 13.1 0.9 0.087 12.7 0.1 1.6 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 tRNA-synt_1 PF00133.22 KKA02151.1 - 3.6e-227 755.4 0.2 4.6e-226 751.8 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKA02151.1 - 2.4e-30 105.5 2.8 4e-30 104.8 1.3 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKA02151.1 - 3.4e-14 52.4 0.2 5.7e-08 31.9 0.0 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KKA02151.1 - 2.1e-08 33.9 0.1 2.5e-07 30.4 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KKA02151.1 - 0.0099 15.3 2.1 0.65 9.3 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Nop52 PF05997.12 KKA02151.1 - 0.012 15.4 1.6 0.049 13.4 0.0 2.2 2 0 0 2 2 2 0 Nucleolar protein,Nop52 YebO PF13974.6 KKA02151.1 - 1.1 9.4 3.5 2.9 8.0 3.5 1.7 1 0 0 1 1 1 0 YebO-like protein AAA_23 PF13476.6 KKA02151.1 - 4 7.9 16.7 0.43 11.0 1.5 2.6 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.12 KKA02152.1 - 6.2e-25 87.2 0.5 1.3e-24 86.2 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKA02152.1 - 7.4e-24 84.2 0.5 1.1e-23 83.6 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKA02152.1 - 3.1e-05 25.0 0.0 4.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RcnB PF11776.8 KKA02152.1 - 0.036 14.1 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator Mito_carr PF00153.27 KKA02153.1 - 1.5e-50 169.1 10.2 2.1e-16 59.6 1.7 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKA02153.1 - 0.00089 18.5 3.8 0.53 9.4 0.0 3.3 3 1 0 3 3 3 2 Gammaproteobacterial serine protease CDP-OH_P_transf PF01066.21 KKA02154.1 - 1.4e-12 48.2 0.3 1.4e-12 48.2 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_N PF08240.12 KKA02155.1 - 6e-25 87.2 0.2 1.4e-24 86.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKA02155.1 - 6.2e-25 87.7 1.1 9.5e-25 87.1 1.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKA02155.1 - 1e-07 33.1 0.1 2e-07 32.1 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase RcnB PF11776.8 KKA02155.1 - 0.06 13.4 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator DapB_N PF01113.20 KKA02155.1 - 0.39 10.8 2.1 3.3 7.8 2.1 2.2 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TRAM_LAG1_CLN8 PF03798.16 KKA02156.1 - 4.8e-32 111.3 20.4 4.8e-32 111.3 20.4 1.5 2 0 0 2 2 2 1 TLC domain PH PF00169.29 KKA02157.1 - 0.008 16.7 0.4 0.039 14.5 0.1 2.4 2 0 0 2 2 2 1 PH domain Apolipoprotein PF01442.18 KKA02157.1 - 0.05 13.5 1.8 0.11 12.4 1.8 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF349 PF03993.12 KKA02157.1 - 0.088 13.1 2.1 0.36 11.2 2.1 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Med31 PF05669.12 KKA02158.1 - 0.077 13.0 2.9 0.24 11.4 2.9 1.9 1 0 0 1 1 1 0 SOH1 Pept_S41_N PF18294.1 KKA02158.1 - 0.17 11.9 2.3 8.9 6.4 0.1 3.0 3 0 0 3 3 3 0 Peptidase S41 N-terminal domain Telomere_reg-2 PF10193.9 KKA02159.1 - 2.1e-08 34.5 0.0 4.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein HSP70 PF00012.20 KKA02159.1 - 0.0023 16.2 0.2 0.004 15.4 0.2 1.3 1 0 0 1 1 1 1 Hsp70 protein PI-PLC-X PF00388.19 KKA02159.1 - 0.019 14.6 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Fmp27_WPPW PF10359.9 KKA02160.1 - 2.2e-80 270.9 13.5 5.7e-80 269.5 13.5 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 KKA02160.1 - 2.4e-70 237.7 21.9 3.2e-47 161.5 1.4 3.8 3 1 1 4 4 4 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KKA02160.1 - 4.7e-49 166.5 0.0 1.3e-48 165.0 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KKA02160.1 - 1.2e-32 113.0 2.9 1.2e-32 113.0 2.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KKA02160.1 - 5.9e-18 65.5 0.1 4.8e-17 62.5 0.1 2.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Rhomboid PF01694.22 KKA02161.1 - 9.6e-23 80.8 17.4 9.6e-23 80.8 17.4 1.8 1 1 1 2 2 2 1 Rhomboid family DUF5613 PF18467.1 KKA02161.1 - 0.013 15.9 1.0 0.013 15.9 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) DUF3641 PF12345.8 KKA02162.1 - 0.11 12.5 1.1 0.23 11.5 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) Pescadillo_N PF06732.11 KKA02163.1 - 3.7e-110 367.8 8.3 3.7e-110 367.8 8.3 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KKA02163.1 - 1.3e-10 41.5 0.0 3.7e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain QSOX_Trx1 PF18108.1 KKA02163.1 - 0.02 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 QSOX Trx-like domain Hira PF07569.11 KKA02163.1 - 0.038 13.7 0.9 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 TUP1-like enhancer of split RecO_C PF02565.15 KKA02163.1 - 0.078 12.8 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Recombination protein O C terminal SHP PF03579.13 KKA02163.1 - 0.16 12.0 0.2 0.16 12.0 0.2 1.7 2 0 0 2 2 2 0 Small hydrophobic protein UPF0061 PF02696.14 KKA02165.1 - 3.1e-117 392.2 3.2 4e-117 391.9 3.2 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family VirDNA-topo-I_N PF09266.10 KKA02165.1 - 0.028 14.6 0.1 0.089 13.0 0.1 1.9 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Dehydrin PF00257.19 KKA02167.1 - 0.083 13.4 0.7 0.083 13.4 0.7 2.2 1 1 0 2 2 2 0 Dehydrin Cation_efflux PF01545.21 KKA02168.1 - 6.6e-35 120.7 12.3 1e-34 120.1 12.3 1.3 1 0 0 1 1 1 1 Cation efflux family zf-C4H2 PF10146.9 KKA02168.1 - 0.0051 17.2 0.2 0.0093 16.3 0.2 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein Aldo_ket_red PF00248.21 KKA02169.1 - 3.7e-36 124.8 0.0 4.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_synt_4 PF04669.13 KKA02170.1 - 4.7e-14 52.4 0.4 7.4e-12 45.2 0.4 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis MoCF_biosynth PF00994.24 KKA02171.1 - 7.1e-26 90.6 0.0 1.4e-25 89.6 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain KMP11 PF03037.16 KKA02171.1 - 0.24 12.2 5.3 0.92 10.3 1.0 3.2 3 1 1 4 4 4 0 Kinetoplastid membrane protein 11 UPF0113_N PF17833.1 KKA02174.1 - 2.6e-31 108.0 1.5 6.2e-31 106.8 1.0 1.8 2 0 0 2 2 2 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KKA02174.1 - 1.8e-25 89.0 0.0 3.7e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain YPEB PF14620.6 KKA02174.1 - 0.092 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 YpeB sporulation DAP3 PF10236.9 KKA02175.1 - 3.1e-24 85.7 2.7 5.3e-24 85.0 2.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2439 PF10382.9 KKA02175.1 - 0.14 12.5 1.4 1.4 9.3 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2439) PHD PF00628.29 KKA02176.1 - 2e-05 24.4 16.4 2e-05 24.4 16.4 2.2 2 0 0 2 2 2 1 PHD-finger GATA PF00320.27 KKA02176.1 - 0.0029 17.2 4.3 0.0029 17.2 4.3 2.7 3 0 0 3 3 3 1 GATA zinc finger zf-HC5HC2H PF13771.6 KKA02176.1 - 0.41 10.9 14.3 0.026 14.8 7.8 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KKA02177.1 - 2.7e-08 34.0 7.8 2.7e-08 34.0 7.8 3.3 2 1 1 3 3 3 1 PHD-zinc-finger like domain PHD PF00628.29 KKA02177.1 - 2.6e-07 30.4 35.2 0.00022 21.1 12.2 3.9 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 KKA02177.1 - 1.5e-05 24.4 7.9 1.5e-05 24.4 7.9 5.6 8 0 0 8 8 8 2 PHD-finger PHD_3 PF13922.6 KKA02177.1 - 0.0029 18.0 0.9 0.0029 18.0 0.9 3.2 3 0 0 3 3 3 1 PHD domain of transcriptional enhancer, Asx Prok-RING_1 PF14446.6 KKA02177.1 - 0.024 14.6 4.1 0.024 14.6 4.1 4.6 3 2 0 4 4 4 0 Prokaryotic RING finger family 1 LRR_9 PF14580.6 KKA02178.1 - 7.3e-06 25.6 9.9 9.3e-06 25.3 7.0 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KKA02178.1 - 0.29 11.6 27.8 0.97 10.0 2.5 4.3 1 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF1771 PF08590.10 KKA02179.1 - 8.1e-16 58.2 10.7 8.1e-16 58.2 10.7 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KKA02179.1 - 9.4e-08 32.3 0.0 2.6e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Smr domain Mac PF12464.8 KKA02179.1 - 0.18 12.0 4.8 0.33 11.2 0.9 3.1 2 1 1 3 3 3 0 Maltose acetyltransferase CD225 PF04505.12 KKA02179.1 - 0.19 11.9 0.2 0.4 10.9 0.2 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein AFT PF08731.11 KKA02180.1 - 7.4e-35 119.7 7.3 7.4e-35 119.7 7.3 2.3 2 0 0 2 2 2 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 KKA02180.1 - 0.12 12.4 1.7 4 7.5 0.3 2.5 2 0 0 2 2 2 0 MuDR family transposase RNA_POL_M_15KD PF02150.16 KKA02181.1 - 3.2e-14 52.5 4.5 3.2e-14 52.5 4.5 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KKA02181.1 - 5.2e-13 48.6 5.0 5.2e-13 48.6 5.0 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 KKA02181.1 - 0.017 15.1 10.2 0.05 13.6 1.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF2387 PF09526.10 KKA02181.1 - 0.19 11.9 0.3 0.19 11.9 0.3 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-UBP PF02148.19 KKA02181.1 - 0.28 11.5 7.0 1.7 9.0 1.1 2.4 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein RPA_interact_C PF14768.6 KKA02181.1 - 1.6 9.4 10.3 5.4 7.7 1.4 2.6 2 1 0 2 2 2 0 Replication protein A interacting C-terminal A2L_zn_ribbon PF08792.10 KKA02181.1 - 3.9 7.3 18.8 3.3 7.5 0.4 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain CK_II_beta PF01214.18 KKA02181.1 - 3.9 7.2 8.7 0.83 9.4 1.7 2.1 2 0 0 2 2 2 0 Casein kinase II regulatory subunit Rpr2 PF04032.16 KKA02181.1 - 5.2 7.4 10.4 2.5e+02 2.0 10.4 2.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1595 PF12760.7 KKA02181.1 - 8.3 6.5 13.3 8.4 6.5 1.5 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.12 KKA02181.1 - 8.7 6.7 18.4 5.2 7.4 5.6 3.3 2 2 1 3 3 3 0 TFIIH C1-like domain Glyco_hydro_3_C PF01915.22 KKA02182.1 - 1.3e-58 198.3 0.0 2.3e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKA02182.1 - 4.6e-36 124.8 0.0 7.8e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKA02182.1 - 1.6e-19 69.8 0.1 3.7e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KKA02182.1 - 2e-18 66.6 0.0 3.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GDPD PF03009.17 KKA02183.1 - 5.9e-10 39.3 0.0 1.8e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family NAGLU_C PF12972.7 KKA02183.1 - 0.0024 17.5 0.2 0.18 11.3 0.0 2.1 2 0 0 2 2 2 2 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF5010 PF16402.5 KKA02183.1 - 0.064 12.1 1.7 0.14 10.9 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5010) SCA7 PF08313.12 KKA02184.1 - 1.1e-16 60.5 0.8 4.4e-16 58.5 0.8 2.1 1 0 0 1 1 1 1 SCA7, zinc-binding domain FYVE_2 PF02318.16 KKA02184.1 - 0.022 15.0 0.7 0.022 15.0 0.7 4.1 5 0 0 5 5 5 0 FYVE-type zinc finger JmjC PF02373.22 KKA02185.1 - 0.16 12.4 1.8 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase MFS_1 PF07690.16 KKA02187.1 - 1.1e-33 116.7 27.7 1.9e-21 76.4 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA02187.1 - 4.6e-15 55.4 28.6 1.9e-09 36.9 9.7 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter Ribosomal_L3 PF00297.22 KKA02187.1 - 0.19 10.7 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 Mrr_cat_2 PF13156.6 KKA02188.1 - 1.2e-07 31.7 0.2 1.7e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF2034 PF10356.9 KKA02188.1 - 5.5e-07 29.2 3.0 1.8e-05 24.2 0.1 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KKA02188.1 - 2.4e-05 24.3 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease AMPK1_CBM PF16561.5 KKA02189.1 - 1.4e-08 34.9 2.6 2.9e-08 33.8 2.6 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase TAF PF02969.17 KKA02190.1 - 2e-19 69.5 0.8 3.5e-18 65.5 0.1 2.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KKA02190.1 - 3.4e-14 52.9 0.0 8.7e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KKA02190.1 - 0.0016 18.8 1.9 0.0075 16.6 0.0 2.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 FAD_binding_1 PF00667.20 KKA02190.1 - 0.019 14.5 2.3 0.16 11.5 0.4 2.4 2 0 0 2 2 2 0 FAD binding domain CBFD_NFYB_HMF PF00808.23 KKA02190.1 - 0.02 15.2 0.2 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKA02190.1 - 0.039 14.0 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1408 PF07193.11 KKA02190.1 - 0.078 13.1 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Aldolase_II PF00596.21 KKA02191.1 - 5.6e-41 140.5 0.3 7.3e-41 140.1 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aim21 PF11489.8 KKA02192.1 - 2.1 7.2 10.6 6.6 5.5 10.6 1.7 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 21 Inositol_P PF00459.25 KKA02193.1 - 1.6e-38 132.8 0.0 4.4e-38 131.4 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Sod_Cu PF00080.20 KKA02193.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) ABC2_membrane_3 PF12698.7 KKA02194.1 - 6.1 5.9 4.8 7.1 5.6 4.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein V-SNARE_C PF12352.8 KKA02195.1 - 1.6e-07 31.5 2.7 2.8e-07 30.7 1.0 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KKA02195.1 - 1.3e-05 25.0 1.5 1.3e-05 25.0 1.5 2.8 2 1 0 2 2 2 1 Sec20 Tup_N PF08581.10 KKA02195.1 - 0.0073 16.6 5.6 0.97 9.8 0.3 2.6 2 0 0 2 2 2 2 Tup N-terminal DUF3973 PF13119.6 KKA02195.1 - 0.13 12.4 0.2 0.34 11.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Spc7 PF08317.11 KKA02195.1 - 0.19 10.6 14.1 0.061 12.2 7.4 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF5339 PF17274.2 KKA02195.1 - 0.5 11.2 8.3 0.38 11.6 1.7 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5339) TACC_C PF05010.14 KKA02195.1 - 0.71 9.6 18.2 0.035 13.9 10.3 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF745 PF05335.13 KKA02195.1 - 0.76 9.5 6.5 11 5.7 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) GrpE PF01025.19 KKA02195.1 - 0.78 9.4 13.5 1.4 8.6 6.3 2.6 1 1 1 2 2 2 0 GrpE LMBR1 PF04791.16 KKA02195.1 - 0.84 8.5 12.9 0.35 9.7 7.2 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF1640 PF07798.11 KKA02196.1 - 1.1e-25 90.7 12.5 1.4e-25 90.4 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Uds1 PF15456.6 KKA02196.1 - 0.0019 18.3 1.9 0.0019 18.3 1.9 1.7 1 1 1 2 2 2 1 Up-regulated During Septation COMMD1_N PF17221.3 KKA02196.1 - 0.022 15.1 2.9 1.2 9.5 0.2 2.3 1 1 1 2 2 2 0 COMMD1 N-terminal domain DHR10 PF18595.1 KKA02196.1 - 1.3 9.2 8.0 0.4 10.8 3.1 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain V-ATPase_G PF03179.15 KKA02196.1 - 3.3 8.3 11.6 0.18 12.4 0.8 2.7 1 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit zf-C2H2_jaz PF12171.8 KKA02197.1 - 4e-11 42.9 5.3 8e-11 41.9 5.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKA02197.1 - 0.00019 21.7 3.8 0.0003 21.1 3.8 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKA02197.1 - 0.00025 21.3 0.1 0.00057 20.2 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KKA02197.1 - 0.0023 17.7 2.4 0.0041 16.8 2.4 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF2701 PF10857.8 KKA02197.1 - 0.044 13.8 0.3 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) zf-C2H2_4 PF13894.6 KKA02197.1 - 0.078 13.8 1.7 0.17 12.8 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Levi_coat PF01819.17 KKA02198.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Levivirus coat protein DUF1462 PF07315.11 KKA02198.1 - 0.11 12.8 2.2 0.25 11.6 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1462) Med14 PF08638.11 KKA02199.1 - 2.6e-31 108.5 6.5 3e-31 108.4 4.2 2.4 2 0 0 2 2 2 1 Mediator complex subunit MED14 TPR_18 PF13512.6 KKA02199.1 - 0.15 12.2 0.7 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NADH-UOR_E PF16514.5 KKA02200.1 - 0.011 16.0 2.8 0.044 14.1 2.0 2.4 1 1 1 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E Cu-oxidase_2 PF07731.14 KKA02201.1 - 2.3e-45 153.7 5.4 2.5e-41 140.6 1.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKA02201.1 - 7.1e-27 93.8 10.5 5.3e-26 91.0 0.7 3.9 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KKA02201.1 - 1.1e-18 67.9 3.7 6.8e-16 58.8 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Zn_clus PF00172.18 KKA02202.1 - 0.29 11.3 9.6 0.96 9.6 4.6 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_6 PF13516.6 KKA02204.1 - 4.2e-11 42.0 7.5 0.065 13.3 0.4 7.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KKA02204.1 - 2.1e-07 31.2 14.9 0.33 11.5 3.9 6.8 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKA02204.1 - 0.0028 17.4 10.8 5 7.0 0.3 5.9 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KKA02204.1 - 0.0053 17.1 6.2 16 6.6 0.1 6.6 7 0 0 7 7 7 1 Leucine Rich Repeat Mpp10 PF04006.12 KKA02204.1 - 0.0094 14.4 7.0 0.014 13.8 7.0 1.2 1 0 0 1 1 1 1 Mpp10 protein DEAD PF00270.29 KKA02205.1 - 2.9e-23 82.5 0.3 1.4e-22 80.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02205.1 - 1.2e-21 77.1 1.7 9.6e-16 58.1 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.10 KKA02205.1 - 4.4e-17 61.9 1.0 2.4e-16 59.5 0.1 2.5 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 KKA02205.1 - 4.2e-13 49.8 8.8 6e-13 49.3 6.0 2.9 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KKA02205.1 - 1.2e-07 31.9 0.0 1.2e-07 31.9 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PAS PF00989.25 KKA02206.1 - 5.6e-09 36.0 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KKA02206.1 - 4.1e-06 26.8 11.8 7.2e-06 26.0 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_8 PF13188.7 KKA02206.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 KKA02206.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 KKA02206.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold zf-rbx1 PF12678.7 KKA02207.1 - 1.1e-08 35.2 3.1 2.6e-08 34.0 3.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKA02207.1 - 3.1e-08 33.8 5.2 1.3e-07 31.8 1.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKA02207.1 - 1.2e-05 25.0 7.4 7.6e-05 22.5 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKA02207.1 - 1.7e-05 24.6 3.1 8.6e-05 22.3 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKA02207.1 - 5.3e-05 23.0 4.9 0.0001 22.1 4.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKA02207.1 - 0.00045 20.1 0.3 0.00045 20.1 0.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKA02207.1 - 0.0018 18.1 0.4 0.0018 18.1 0.4 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKA02207.1 - 0.0022 18.0 1.8 0.0073 16.3 1.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKA02207.1 - 0.0064 16.1 0.5 0.014 15.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KKA02207.1 - 0.013 15.6 3.0 0.013 15.5 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KKA02207.1 - 0.016 15.4 0.5 0.039 14.2 0.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family CTU2 PF10288.9 KKA02207.1 - 0.078 13.2 4.9 1.4 9.2 0.5 2.8 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING-like PF08746.11 KKA02207.1 - 0.15 12.4 1.8 0.29 11.5 1.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KKA02207.1 - 0.91 9.3 2.8 8.5 6.2 0.6 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KKA02207.1 - 2.8 8.2 6.3 0.37 11.0 1.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KKA02207.1 - 3.6 7.3 6.2 0.51 10.0 1.4 2.0 2 0 0 2 2 2 0 P-11 zinc finger Ras PF00071.22 KKA02208.1 - 5e-50 169.3 0.0 6.1e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA02208.1 - 1.5e-30 105.9 0.1 4.2e-30 104.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA02208.1 - 5.3e-11 42.3 0.0 7.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKA02208.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKA02208.1 - 0.0014 19.0 0.1 0.0078 16.6 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KKA02208.1 - 0.0026 17.1 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KKA02208.1 - 0.021 14.3 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KKA02208.1 - 0.024 14.5 0.1 8.2 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KKA02208.1 - 0.024 13.8 1.9 1.7 7.7 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit ATPase PF06745.13 KKA02208.1 - 0.03 13.7 0.2 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KKA02208.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 KKA02208.1 - 0.032 13.8 0.3 0.15 11.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KKA02208.1 - 0.05 13.3 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKA02208.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KKA02208.1 - 0.079 13.1 0.5 0.22 11.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKA02208.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KKA02208.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KKA02208.1 - 0.15 11.3 0.3 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Septin Spermine_synth PF01564.17 KKA02209.1 - 0.028 13.8 1.4 0.056 12.9 1.4 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain ProRS-C_1 PF09180.11 KKA02209.1 - 0.057 13.6 0.9 8.8 6.6 0.2 2.6 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal ING PF12998.7 KKA02209.1 - 3.6 8.2 12.9 0.33 11.6 0.7 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Ferrochelatase PF00762.19 KKA02210.1 - 1.7e-94 316.5 0.0 3.2e-94 315.6 0.0 1.4 2 0 0 2 2 2 1 Ferrochelatase EMP24_GP25L PF01105.24 KKA02211.1 - 0.027 14.4 2.5 0.037 14.0 2.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MCM PF00493.23 KKA02212.1 - 1.3e-103 344.9 0.0 2.1e-103 344.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKA02212.1 - 5e-36 123.3 0.2 9.2e-36 122.5 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKA02212.1 - 1.1e-29 102.7 0.7 3.6e-29 101.0 0.7 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKA02212.1 - 7.5e-17 61.8 2.7 1.9e-16 60.5 2.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKA02212.1 - 1.6e-06 27.7 0.0 0.00087 18.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKA02212.1 - 6.5e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKA02212.1 - 0.0005 19.9 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KKA02212.1 - 0.037 14.7 0.4 0.12 13.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 KKA02212.1 - 0.077 12.7 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain TetR_C_24 PF17932.1 KKA02213.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_16 PF10294.9 KKA02214.1 - 1e-18 67.6 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KKA02214.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKA02214.1 - 0.00039 20.0 0.1 0.00078 19.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KKA02214.1 - 0.0013 19.4 0.1 0.0022 18.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA02214.1 - 0.0094 16.6 0.0 0.016 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KKA02214.1 - 0.075 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 KKA02214.1 - 0.088 12.6 0.1 0.23 11.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KKA02214.1 - 0.15 11.4 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF370 PF04025.12 KKA02215.1 - 0.015 15.4 0.6 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF370) CutA1 PF03091.15 KKA02215.1 - 0.26 11.1 2.0 2.9 7.8 0.2 2.3 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein FTR1 PF03239.14 KKA02216.1 - 1.5e-90 303.5 8.9 1.8e-90 303.2 8.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family SPC25 PF06703.11 KKA02216.1 - 0.77 9.5 8.7 36 4.1 8.7 2.7 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MgtE PF01769.16 KKA02216.1 - 1.1 9.6 14.9 1.2 9.5 2.1 3.0 3 1 0 3 3 3 0 Divalent cation transporter Rhomboid_SP PF12595.8 KKA02217.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Rhomboid serine protease FGE-sulfatase PF03781.16 KKA02217.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 SNF2_N PF00176.23 KKA02218.1 - 8.7e-62 208.8 1.2 3e-61 207.1 0.0 2.5 4 0 0 4 4 4 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KKA02218.1 - 3.3e-23 82.8 6.1 1.5e-22 80.7 5.8 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KKA02218.1 - 1.1e-15 58.0 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02218.1 - 3.3e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKA02218.1 - 4.6e-07 29.3 0.0 4.6e-07 29.3 0.0 3.0 4 0 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DAHP_synth_1 PF00793.20 KKA02220.1 - 6.8e-109 363.0 0.0 8.3e-109 362.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.21 KKA02221.1 - 3.3e-45 154.3 0.3 3.1e-44 151.1 0.1 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.28 KKA02221.1 - 1.9e-16 60.4 0.0 3.1e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KKA02221.1 - 8.6e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KKA02221.1 - 0.0047 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S51 SNO PF01174.19 KKA02221.1 - 0.024 14.5 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 SNO glutamine amidotransferase family BPL_N PF09825.9 KKA02221.1 - 0.048 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal NMO PF03060.15 KKA02221.1 - 0.062 12.7 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Zn_ribbon_2 PF12674.7 KKA02221.1 - 0.12 13.0 3.8 7.1 7.4 0.2 2.8 3 0 0 3 3 3 0 Putative zinc ribbon domain Bystin PF05291.11 KKA02222.1 - 2.1e-112 375.2 0.7 3.4e-112 374.5 0.7 1.3 1 0 0 1 1 1 1 Bystin DUF2624 PF11116.8 KKA02222.1 - 0.018 15.9 2.6 6.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) CDC27 PF09507.10 KKA02222.1 - 1.6 8.0 16.9 2.3 7.5 16.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hydrolase_3 PF08282.12 KKA02222.1 - 2.6 7.7 8.4 5 6.8 8.4 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Use1 PF09753.9 KKA02223.1 - 9.8e-07 28.7 3.8 1.2e-06 28.4 3.8 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 WD40 PF00400.32 KKA02224.1 - 0.026 15.4 3.1 12 7.0 0.1 4.3 3 0 0 3 3 3 0 WD domain, G-beta repeat RINGv PF12906.7 KKA02225.1 - 5.1e-08 32.9 9.3 9.9e-08 32.0 9.3 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KKA02225.1 - 0.003 17.7 7.3 0.0078 16.4 7.3 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KKA02225.1 - 0.0078 16.5 10.8 0.092 13.1 11.3 2.2 1 1 1 2 2 2 1 Ring finger domain C1_2 PF03107.16 KKA02225.1 - 1.2 9.5 9.2 0.84 10.0 5.5 2.3 2 0 0 2 2 2 0 C1 domain zf-rbx1 PF12678.7 KKA02225.1 - 1.9 8.8 7.9 4.4 7.7 7.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 KKA02225.1 - 3.8 7.5 9.7 6.9 6.6 9.7 1.5 1 0 0 1 1 1 0 PHD-finger DUF202 PF02656.15 KKA02225.1 - 8.9 6.8 10.9 0.77 10.2 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF202) tRNA_bind PF01588.20 KKA02226.1 - 1e-26 92.8 0.1 3.6e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Putative tRNA binding domain Viral_protease PF08715.10 KKA02226.1 - 0.0051 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Papain like viral protease CCDC53 PF10152.9 KKA02226.1 - 0.007 16.8 3.6 0.012 16.0 3.6 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Ino80_Iec3 PF14612.6 KKA02226.1 - 0.0091 16.7 5.1 0.02 15.6 5.1 1.5 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RNA_pol_Rpc4 PF05132.14 KKA02226.1 - 0.035 14.5 2.6 0.061 13.8 2.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.12 KKA02226.1 - 0.063 13.5 3.2 0.091 13.0 3.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2894 PF11445.8 KKA02226.1 - 0.1 13.1 2.8 0.17 12.3 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Tim54 PF11711.8 KKA02226.1 - 0.78 8.5 8.8 1.2 7.8 8.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HD_3 PF13023.6 KKA02227.1 - 1.1e-33 116.4 0.3 1.6e-33 116.0 0.3 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KKA02227.1 - 3.2e-09 36.8 0.3 5.2e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KKA02227.1 - 2.3e-05 24.6 0.2 3.7e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 HD domain SNF2_N PF00176.23 KKA02228.1 - 5.8e-72 242.3 4.3 3.1e-71 239.9 4.3 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KKA02228.1 - 1.2e-32 112.3 2.8 1.2e-32 112.3 2.8 4.3 5 0 0 5 5 5 2 SLIDE Helicase_C PF00271.31 KKA02228.1 - 3.1e-20 72.6 0.3 5.7e-19 68.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02228.1 - 9.3e-13 48.5 0.0 9.3e-13 48.5 0.0 4.4 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit HAND PF09110.11 KKA02228.1 - 3.6e-12 47.0 6.1 3.6e-12 47.0 6.1 5.0 5 1 0 5 5 5 1 HAND DEAD PF00270.29 KKA02228.1 - 2e-06 27.7 0.4 8.3e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KKA02228.1 - 0.00065 19.8 0.4 0.12 12.6 0.1 3.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain MPC PF03650.13 KKA02229.1 - 2.2e-38 130.8 0.0 2.4e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers KCH PF16944.5 KKA02229.1 - 0.032 14.0 0.1 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Fungal potassium channel Syja_N PF02383.18 KKA02231.1 - 3.9e-31 108.5 2.9 3.9e-31 108.5 2.9 1.9 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KKA02231.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YfkD PF14167.6 KKA02231.1 - 0.16 11.1 2.4 0.53 9.4 0.1 2.7 2 1 0 2 2 2 0 YfkD-like protein DDOST_48kD PF03345.14 KKA02232.1 - 2.6e-87 293.4 13.3 3.2e-87 293.1 13.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NTF2 PF02136.20 KKA02233.1 - 6.4e-36 123.6 0.7 7.1e-36 123.4 0.7 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 KKA02233.1 - 0.0024 17.1 1.3 0.012 14.8 1.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.6 KKA02233.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DnaJ-X PF14308.6 KKA02234.1 - 2.6e-59 200.2 10.8 2.6e-59 200.2 10.8 2.7 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KKA02234.1 - 5.4e-20 71.3 3.5 2.6e-19 69.1 3.5 2.3 1 0 0 1 1 1 1 DnaJ domain DUF1258 PF06869.12 KKA02234.1 - 0.028 13.9 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Pre-PUA PF17832.1 KKA02235.1 - 2.7e-22 79.2 0.9 4.3e-22 78.6 0.9 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KKA02235.1 - 5.1e-17 61.6 0.2 8.4e-17 60.9 0.2 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KKA02235.1 - 0.54 10.6 2.8 1.9 8.8 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) Gemini_coat PF00844.18 KKA02236.1 - 2.2 7.6 12.5 0.098 12.1 1.2 2.1 1 1 1 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family Mannosyl_trans3 PF11051.8 KKA02237.1 - 7.3e-20 71.4 3.8 4e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Mannosyltransferase putative bZIP_1 PF00170.21 KKA02238.1 - 0.01 15.9 10.5 0.12 12.5 0.3 2.7 2 1 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KKA02238.1 - 0.021 14.9 13.6 0.86 9.7 8.5 2.5 1 1 1 2 2 2 0 Basic region leucine zipper NEMO PF11577.8 KKA02238.1 - 0.048 13.7 0.6 0.048 13.7 0.6 2.3 2 1 1 3 3 3 0 NF-kappa-B essential modulator NEMO DNA_primase_S PF01896.19 KKA02239.1 - 4.9e-44 150.5 0.3 1e-43 149.4 0.3 1.6 1 0 0 1 1 1 1 DNA primase small subunit Suc_Fer-like PF06999.12 KKA02240.1 - 7.5e-33 114.0 0.0 9.9e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like RibD_C PF01872.17 KKA02241.1 - 4.9e-24 85.3 0.0 7.2e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain PRAI PF00697.22 KKA02242.1 - 6.7e-29 101.0 0.3 1.2e-28 100.3 0.3 1.3 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Ntox50 PF15542.6 KKA02242.1 - 0.13 13.1 1.6 7.6 7.4 0.0 3.0 2 2 1 3 3 3 0 Bacterial toxin 50 Pyrophosphatase PF00719.19 KKA02243.1 - 4.2e-57 192.4 0.3 5.6e-57 192.0 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase LSM PF01423.22 KKA02244.1 - 4e-11 42.4 1.3 6.8e-11 41.7 1.3 1.4 1 0 0 1 1 1 1 LSM domain RPA_C PF08784.11 KKA02246.1 - 0.0098 16.5 0.0 0.027 15.1 0.0 1.7 1 1 0 1 1 1 1 Replication protein A C terminal Glyco_hydro_72 PF03198.14 KKA02247.1 - 1.5e-128 428.5 1.5 1.5e-128 428.5 1.5 1.6 2 0 0 2 2 2 1 Glucanosyltransferase Cellulase PF00150.18 KKA02247.1 - 0.0058 16.1 0.1 0.053 12.9 0.1 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CorA PF01544.18 KKA02249.1 - 6.7e-36 124.1 4.9 9.5e-36 123.6 4.9 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DHHC PF01529.20 KKA02249.1 - 0.0044 17.1 0.2 0.0096 16.0 0.2 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase UPF0220 PF05255.11 KKA02250.1 - 6.9e-20 71.2 0.5 8.9e-20 70.9 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.25 KKA02251.1 - 6.8e-54 183.0 0.0 3.1e-53 180.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02251.1 - 2e-21 76.5 0.4 1.6e-20 73.5 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02251.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KKA02251.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Bax1-I PF01027.20 KKA02253.1 - 1.4e-25 90.3 27.0 2e-25 89.8 27.0 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FtsL PF04999.13 KKA02253.1 - 0.32 11.0 2.7 3.5 7.7 0.1 2.8 1 1 1 2 2 2 0 Cell division protein FtsL TRM13 PF05206.14 KKA02254.1 - 3e-66 223.6 10.1 9.7e-66 222.0 10.1 1.8 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 KKA02254.1 - 7.8e-09 35.3 2.3 7.8e-09 35.3 2.3 2.1 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 KKA02254.1 - 0.00023 21.2 8.0 0.00024 21.1 3.9 2.6 2 1 0 2 2 2 1 Methyltransferase domain zf-TRM13_CCCH PF11722.8 KKA02254.1 - 0.009 15.8 3.6 0.023 14.5 0.4 2.6 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Ras PF00071.22 KKA02255.1 - 1.3e-30 106.1 0.2 5.8e-25 87.8 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KKA02255.1 - 2.5e-21 76.1 0.2 3.4e-14 53.1 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA02255.1 - 7.3e-08 32.1 1.3 4.7e-05 22.9 0.2 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKA02255.1 - 0.00022 21.3 0.0 0.0017 18.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKA02255.1 - 0.00035 20.0 0.3 0.014 14.8 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KKA02255.1 - 0.0016 17.9 0.1 0.0076 15.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 KKA02255.1 - 0.032 14.5 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KKA02256.1 - 6.6e-32 109.2 0.4 4.4e-17 61.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKA02256.1 - 1e-12 48.0 0.3 5.9e-06 26.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif KRAB PF01352.27 KKA02256.1 - 0.002 17.8 1.8 0.0041 16.7 1.8 1.5 1 0 0 1 1 1 1 KRAB box RRM_3 PF08777.11 KKA02256.1 - 0.051 13.6 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Tra_M PF05261.11 KKA02257.1 - 1.5 8.8 5.1 3 7.8 0.1 3.1 3 0 0 3 3 3 0 TraM protein, DNA-binding Redoxin PF08534.10 KKA02258.1 - 3.8e-22 78.6 0.0 4.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKA02258.1 - 1.6e-09 37.7 0.0 2.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Robl_LC7 PF03259.17 KKA02258.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 2 0 0 2 2 2 0 Roadblock/LC7 domain MFS_1 PF07690.16 KKA02259.1 - 1.6e-25 89.8 30.1 1.6e-25 89.8 30.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA02259.1 - 4.4e-06 25.8 9.0 4.4e-06 25.8 9.0 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter GCR1_C PF12550.8 KKA02260.1 - 6.7e-17 61.6 1.0 1.7e-16 60.3 0.1 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HAP1_N PF04849.13 KKA02260.1 - 0.00019 20.8 2.4 0.00034 19.9 2.4 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF2335 PF10097.9 KKA02260.1 - 0.1 12.5 0.2 0.36 10.8 0.2 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) bZIP_2 PF07716.15 KKA02260.1 - 0.15 12.2 1.6 0.43 10.7 1.6 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Tropomyosin_1 PF12718.7 KKA02260.1 - 3.2 7.9 9.4 3.9 7.6 7.3 2.1 2 1 0 2 2 2 0 Tropomyosin like Tir_receptor_C PF07489.11 KKA02260.1 - 7.6 6.4 9.6 1.8 8.5 3.9 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus PAP_assoc PF03828.19 KKA02261.1 - 4.1e-15 55.7 0.3 7.2e-14 51.7 0.0 2.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KKA02261.1 - 1.9e-14 53.7 0.0 1.9e-14 53.7 0.0 2.9 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKA02261.1 - 0.0061 16.6 2.0 0.0078 16.3 0.0 2.2 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Topo-VIb_trans PF09239.11 KKA02261.1 - 0.2 11.4 3.2 1.2 9.0 0.1 2.7 3 0 0 3 3 3 0 Topoisomerase VI B subunit, transducer Chitin_synth_1 PF01644.17 KKA02262.1 - 3.6e-66 222.2 0.3 6e-66 221.4 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KKA02262.1 - 1.3e-26 93.3 4.5 4.8e-19 68.4 0.0 2.9 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 KKA02262.1 - 2.5e-21 75.4 0.0 7.3e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KKA02262.1 - 5.2e-10 39.6 0.6 5.2e-10 39.6 0.6 2.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKA02262.1 - 0.0015 18.5 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 KKA02263.1 - 1.6e-245 815.7 2.5 2.1e-245 815.3 2.5 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KKA02263.1 - 2.9e-11 43.6 0.1 7.3e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKA02263.1 - 2.8e-08 33.9 0.0 2.2e-06 27.7 0.0 2.4 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKA02263.1 - 1.7e-05 24.4 0.0 0.00037 20.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKA02263.1 - 0.00029 20.7 0.0 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1418 PF07214.12 KKA02263.1 - 3.8 7.4 5.4 12 5.8 5.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) AAA PF00004.29 KKA02264.1 - 6.9e-18 65.4 0.0 1.3e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKA02264.1 - 4.6e-13 49.3 0.2 3.1e-12 46.6 0.2 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KKA02264.1 - 4.9e-12 46.1 0.4 1.7e-11 44.3 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain RuvB_N PF05496.12 KKA02264.1 - 8.8e-10 38.5 0.0 3.1e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KKA02264.1 - 6.4e-07 29.5 0.0 2.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKA02264.1 - 1.7e-06 28.2 0.2 5.9e-06 26.5 0.1 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 KKA02264.1 - 7.4e-06 25.9 0.1 1e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKA02264.1 - 7.8e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKA02264.1 - 1.9e-05 25.1 0.0 3.6e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKA02264.1 - 2.6e-05 24.0 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKA02264.1 - 0.00017 20.9 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DEAD PF00270.29 KKA02264.1 - 0.00038 20.3 0.3 0.0018 18.1 0.3 1.9 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKA02264.1 - 0.0011 19.2 0.1 0.024 14.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KKA02264.1 - 0.0016 17.9 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 KKA02264.1 - 0.0019 17.9 0.4 0.023 14.5 0.4 2.2 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KKA02264.1 - 0.0021 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 KKA02264.1 - 0.0035 16.7 0.1 0.0072 15.6 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKA02264.1 - 0.0038 17.6 0.3 0.09 13.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KKA02264.1 - 0.0039 17.2 0.0 0.37 10.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KKA02264.1 - 0.005 17.4 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKA02264.1 - 0.0061 16.6 0.1 0.022 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KKA02264.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KKA02264.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKA02264.1 - 0.065 12.6 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Clat_adaptor_s PF01217.20 KKA02264.1 - 0.092 12.7 0.2 0.092 12.7 0.2 1.7 2 0 0 2 2 1 0 Clathrin adaptor complex small chain AAA_28 PF13521.6 KKA02264.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKA02264.1 - 0.11 12.1 0.1 0.37 10.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKA02264.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 KKA02265.1 - 1.7e-21 76.9 6.9 3.8e-17 62.7 1.2 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Pkinase PF00069.25 KKA02266.1 - 1.8e-62 211.1 5.6 3.5e-62 210.2 0.0 3.1 2 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02266.1 - 1e-48 165.9 0.9 2.2e-48 164.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KKA02266.1 - 6.6e-23 80.8 1.7 1.6e-22 79.6 0.2 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 KKA02266.1 - 4.5e-10 40.0 0.2 1.4e-09 38.4 0.2 1.9 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KKA02266.1 - 5.5e-05 22.1 0.0 5.5e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KKA02266.1 - 0.022 14.1 0.1 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Tcp10_C PF07202.13 KKA02266.1 - 0.089 12.7 0.8 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 T-complex protein 10 C-terminus PH_11 PF15413.6 KKA02266.1 - 6.9 7.2 7.8 0.96 9.9 0.4 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain Rep_fac_C PF08542.11 KKA02267.1 - 3.6e-16 59.3 0.1 1.7e-15 57.2 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KKA02267.1 - 7.6e-12 45.8 0.1 1.3e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKA02267.1 - 8.2e-11 41.9 0.1 1.8e-09 37.6 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KKA02267.1 - 1.6e-06 28.2 0.1 2.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKA02267.1 - 0.00012 22.3 0.0 0.003 17.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KKA02267.1 - 0.00016 21.5 0.7 0.00031 20.6 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KKA02267.1 - 0.00054 20.4 0.0 0.0021 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KKA02267.1 - 0.0014 19.0 0.0 0.0059 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKA02267.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKA02267.1 - 0.0018 18.0 0.0 0.0072 16.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KKA02267.1 - 0.002 17.3 0.0 0.034 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 KKA02267.1 - 0.0023 18.2 0.0 0.0063 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 KKA02267.1 - 0.0024 17.3 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KKA02267.1 - 0.0026 17.7 0.0 0.0071 16.3 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 KKA02267.1 - 0.0074 16.1 0.1 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKA02267.1 - 0.0078 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DMA PF03474.14 KKA02267.1 - 0.0098 15.5 0.1 0.31 10.7 0.0 2.6 2 0 0 2 2 2 1 DMRTA motif T2SSE PF00437.20 KKA02267.1 - 0.014 14.5 0.1 0.044 12.8 0.1 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 KKA02267.1 - 0.041 13.8 0.2 0.76 9.7 0.0 2.3 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 KKA02267.1 - 0.079 13.4 0.1 0.19 12.1 0.1 1.8 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KKA02267.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KKA02267.1 - 0.097 12.6 0.1 0.69 9.8 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase AAA_3 PF07726.11 KKA02267.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KKA02267.1 - 0.18 10.8 0.0 0.76 8.7 0.0 1.8 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Vps52 PF04129.12 KKA02268.1 - 4e-15 55.6 33.8 2.7e-14 52.8 33.7 2.1 1 1 0 1 1 1 1 Vps52 / Sac2 family DUF4971 PF16341.5 KKA02268.1 - 0.00029 20.7 0.1 0.0011 18.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4971) RNA_GG_bind PF10258.9 KKA02268.1 - 0.21 11.7 2.6 0.19 11.8 0.6 2.0 2 0 0 2 2 2 0 PHAX RNA-binding domain MVP_shoulder PF11978.8 KKA02268.1 - 0.32 11.0 6.3 0.36 10.9 2.3 2.8 2 0 0 2 2 2 0 Shoulder domain SCO1-SenC PF02630.14 KKA02270.1 - 3.4e-50 169.4 0.0 4.7e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KKA02270.1 - 8.1e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKA02270.1 - 0.00029 20.6 0.0 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 Redoxin MitMem_reg PF13012.6 KKA02270.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.7 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Thioredoxin_8 PF13905.6 KKA02270.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like YchF-GTPase_C PF06071.13 KKA02271.1 - 2.9e-36 123.5 0.3 7.1e-36 122.3 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KKA02271.1 - 1.3e-18 67.1 0.0 4.4e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKA02271.1 - 6.3e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KKA02271.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 TGS domain PQ-loop PF04193.14 KKA02272.1 - 4.9e-40 135.1 15.7 4.5e-21 74.4 4.6 3.0 2 0 0 2 2 2 2 PQ loop repeat Steroid_dh PF02544.16 KKA02272.1 - 0.019 15.0 1.4 0.058 13.4 1.4 1.8 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ER_lumen_recept PF00810.18 KKA02272.1 - 0.24 12.2 0.2 0.24 12.2 0.2 3.4 3 1 1 4 4 4 0 ER lumen protein retaining receptor MtN3_slv PF03083.16 KKA02272.1 - 3.5 7.7 12.2 0.051 13.6 2.3 3.0 3 2 1 4 4 4 0 Sugar efflux transporter for intercellular exchange NMN_transporter PF04973.12 KKA02272.1 - 9.7 6.1 19.4 1.1 9.2 4.2 3.3 3 1 1 4 4 4 0 Nicotinamide mononucleotide transporter HR1 PF02185.16 KKA02273.1 - 0.47 10.6 8.5 0.052 13.7 3.7 1.9 2 0 0 2 2 2 0 Hr1 repeat MutS_V PF00488.21 KKA02274.1 - 3.8e-65 219.4 0.2 8.7e-65 218.3 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKA02274.1 - 1.2e-24 87.6 1.5 1.2e-24 87.6 1.5 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KKA02274.1 - 3e-09 37.3 0.1 2.7e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KKA02274.1 - 5.6e-08 33.0 1.0 5.6e-08 33.0 1.0 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 KKA02274.1 - 0.0029 17.8 0.1 0.008 16.4 0.1 1.7 1 0 0 1 1 1 1 MutS domain I SRI PF08236.11 KKA02274.1 - 0.039 14.1 2.1 0.15 12.2 2.1 2.1 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain MetOD2 PF18548.1 KKA02274.1 - 0.62 10.2 3.0 7.5 6.7 0.1 3.4 2 0 0 2 2 2 0 Metanogen output domain 2 PTR2 PF00854.21 KKA02275.1 - 2.3e-45 155.1 6.1 3.2e-45 154.7 6.1 1.1 1 0 0 1 1 1 1 POT family NEMP PF10225.9 KKA02275.1 - 0.078 12.6 2.0 1.1 8.8 0.8 2.5 2 0 0 2 2 2 0 NEMP family Cpta_toxin PF07254.12 KKA02275.1 - 0.44 10.5 1.5 6 6.9 1.4 2.6 1 1 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system PTR2 PF00854.21 KKA02276.1 - 8.7e-45 153.2 8.7 1.2e-44 152.7 8.7 1.1 1 0 0 1 1 1 1 POT family TcpS PF17456.2 KKA02276.1 - 0.027 14.5 0.5 0.059 13.4 0.5 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S PsaM PF07465.13 KKA02276.1 - 0.28 10.9 1.5 0.97 9.2 1.5 1.9 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) DUF4257 PF14074.6 KKA02276.1 - 0.29 11.4 2.8 0.36 11.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) tRNA_m1G_MT PF01746.21 KKA02277.1 - 3e-21 76.0 2.6 5.8e-21 75.1 0.1 2.2 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase NPH-II PF12011.8 KKA02277.1 - 0.0091 15.9 3.5 2 8.3 0.0 2.3 2 0 0 2 2 2 2 RNA helicase NPH-II DUF3328 PF11807.8 KKA02277.1 - 0.13 12.0 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) MFS_1 PF07690.16 KKA02279.1 - 2.4e-18 66.2 54.0 1.7e-15 56.9 30.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.6 KKA02279.1 - 0.0023 17.6 0.1 1.4 8.7 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4538) Wzz PF02706.15 KKA02279.1 - 8.8 6.7 9.0 1.5 9.1 0.1 2.9 3 0 0 3 3 3 0 Chain length determinant protein Prefoldin PF02996.17 KKA02280.1 - 9.5e-20 70.7 3.6 1.6e-19 69.9 3.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KKA02280.1 - 0.00016 21.6 4.9 0.02 14.8 0.1 2.6 2 0 0 2 2 2 2 Prefoldin subunit Fib_alpha PF08702.10 KKA02280.1 - 0.021 15.0 12.6 0.36 11.0 3.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KKA02280.1 - 0.12 12.1 13.9 0.039 13.8 7.8 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 APG17 PF04108.12 KKA02280.1 - 0.15 11.2 9.0 0.21 10.7 9.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 End3 PF12761.7 KKA02280.1 - 0.18 11.9 7.2 0.16 12.1 0.4 2.4 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 KKA02280.1 - 0.25 11.9 4.2 6.1 7.5 0.3 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 KKA02280.1 - 0.37 11.1 6.5 3.3 8.0 3.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KKA02280.1 - 0.77 9.8 7.3 2.9 8.0 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 KKA02280.1 - 1 9.8 10.6 0.16 12.3 1.8 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BRE1 PF08647.11 KKA02280.1 - 1.4 9.1 11.9 2.9 8.0 3.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase PDT PF00800.18 KKA02283.1 - 2.8e-51 173.9 0.0 3.7e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KKA02283.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain TnsE_C PF18623.1 KKA02283.1 - 0.074 13.0 0.3 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 TnsE C-terminal domain HTH_44 PF14641.6 KKA02284.1 - 1.5 9.3 7.3 0.46 10.9 3.5 2.1 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 Med7 PF05983.11 KKA02285.1 - 4.4e-44 150.9 7.8 5.1e-44 150.7 7.8 1.0 1 0 0 1 1 1 1 MED7 protein Hydrolase_4 PF12146.8 KKA02286.1 - 1.2e-14 54.2 0.0 2e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKA02286.1 - 3.1e-07 30.3 0.0 2.4e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKA02286.1 - 0.0032 18.1 0.0 0.0046 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CDC50 PF03381.15 KKA02287.1 - 2e-73 247.3 3.5 3e-73 246.8 3.5 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sigma_reg_N PF13800.6 KKA02287.1 - 3.1 8.2 4.8 0.89 9.9 0.6 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Aminotran_3 PF00202.21 KKA02288.1 - 3.7e-98 328.8 0.0 4.7e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KKA02288.1 - 0.037 13.3 0.0 0.28 10.4 0.0 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase Na_Ca_ex PF01699.24 KKA02289.1 - 1.5e-17 63.9 33.1 9.1e-14 51.7 12.2 4.3 4 1 1 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KKA02289.1 - 0.0013 19.4 10.4 0.0013 19.4 10.4 4.9 4 1 1 5 5 5 1 Inner membrane component domain Sporozoite_P67 PF05642.11 KKA02289.1 - 0.23 9.5 0.0 0.31 9.1 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IF4E PF01652.18 KKA02290.1 - 6.2e-34 117.1 0.5 8.1e-34 116.7 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E 6PF2K PF01591.18 KKA02291.1 - 3e-27 95.4 26.2 1.1e-23 83.7 16.3 3.7 3 1 0 3 3 3 2 6-phosphofructo-2-kinase AAA_33 PF13671.6 KKA02291.1 - 0.00017 21.8 0.1 0.074 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKA02291.1 - 0.04 14.5 0.6 0.37 11.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKA02291.1 - 0.069 12.4 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 KKA02291.1 - 0.28 11.6 2.1 1.2 9.6 0.1 3.2 4 1 0 4 4 4 0 AAA domain DHHC PF01529.20 KKA02292.1 - 1.6e-31 109.1 15.4 1.6e-31 109.1 15.4 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase TssO PF17561.2 KKA02292.1 - 0.048 13.8 0.1 0.048 13.8 0.1 2.2 3 0 0 3 3 3 0 Type VI secretion system, TssO PsbN PF02468.15 KKA02292.1 - 2.5 8.0 6.9 3 7.8 3.4 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) AAA PF00004.29 KKA02293.1 - 9.9e-40 136.0 0.1 9.2e-39 132.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKA02293.1 - 0.00068 19.9 0.3 0.091 13.0 0.0 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KKA02293.1 - 0.00085 19.1 0.0 0.0028 17.4 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KKA02293.1 - 0.0015 18.6 0.0 0.0053 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.10 KKA02293.1 - 0.0025 17.8 0.1 0.045 13.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 KKA02293.1 - 0.0039 17.6 0.1 0.21 12.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KKA02293.1 - 0.004 17.2 0.1 0.057 13.4 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKA02293.1 - 0.0085 16.6 0.1 0.047 14.2 0.0 2.4 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 KKA02293.1 - 0.013 14.8 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KKA02293.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KKA02293.1 - 0.032 14.6 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KKA02293.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKA02293.1 - 0.047 13.1 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKA02293.1 - 0.063 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KKA02293.1 - 0.09 13.2 0.0 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKA02293.1 - 0.094 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3626 PF12294.8 KKA02293.1 - 0.19 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) AAA_25 PF13481.6 KKA02293.1 - 0.4 10.2 0.9 15 5.0 0.2 2.3 1 1 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 KKA02294.1 - 5.4e-84 282.3 0.1 7e-84 281.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.19 KKA02295.1 - 5.9e-54 181.7 0.0 6.6e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TPR_2 PF07719.17 KKA02296.1 - 4.3e-23 79.5 39.6 9.4e-06 25.4 0.0 13.8 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_19 PF14559.6 KKA02296.1 - 6.5e-16 58.6 3.7 0.0065 17.0 0.1 8.3 7 2 1 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKA02296.1 - 4.7e-15 55.7 12.0 0.041 14.2 0.1 8.9 7 3 2 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KKA02296.1 - 1.2e-13 50.2 51.3 1.2e-06 28.1 0.0 11.3 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 KKA02296.1 - 4e-13 48.8 14.9 0.0032 17.1 0.0 6.9 6 0 0 6 6 6 4 TPR repeat TPR_16 PF13432.6 KKA02296.1 - 1.2e-12 48.2 0.0 0.43 11.3 0.0 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKA02296.1 - 3.5e-12 46.0 0.0 0.023 15.5 0.0 8.3 7 1 2 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKA02296.1 - 6.4e-08 32.2 50.4 0.009 16.2 0.0 12.8 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKA02296.1 - 1.8e-06 27.9 11.3 3.3 8.3 0.1 8.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKA02296.1 - 1.5e-05 24.6 8.3 2.8 7.9 0.1 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKA02296.1 - 2.2e-05 24.8 19.4 0.95 10.2 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKA02296.1 - 0.0001 22.1 6.0 0.83 9.8 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA02296.1 - 0.00049 20.3 19.8 0.63 10.3 0.6 7.5 6 3 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KKA02296.1 - 0.0016 18.5 0.1 0.39 10.9 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KKA02296.1 - 0.016 15.8 0.1 1.3 9.8 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 KKA02296.1 - 0.016 14.9 3.8 0.077 12.7 0.4 3.3 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 KKA02296.1 - 0.059 13.4 0.1 0.059 13.4 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat VSG_B PF13206.6 KKA02296.1 - 0.084 12.1 5.2 0.16 11.2 5.2 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain POP1 PF06978.11 KKA02297.1 - 1.1e-46 159.5 12.4 1.1e-46 159.5 12.4 2.4 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 Sugar_tr PF00083.24 KKA02298.1 - 8.8e-150 499.5 37.5 1e-149 499.3 37.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA02298.1 - 5.4e-24 84.8 31.6 4.5e-22 78.4 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 KKA02298.1 - 0.018 14.6 0.6 0.018 14.6 0.6 2.5 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 LMF1 PF06762.14 KKA02298.1 - 1.5 7.9 6.5 3 6.9 6.5 1.5 1 0 0 1 1 1 0 Lipase maturation factor ABC2_membrane PF01061.24 KKA02299.1 - 3e-73 245.7 57.3 1.5e-38 132.4 23.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KKA02299.1 - 7.2e-33 112.4 11.5 3.5e-30 103.7 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KKA02299.1 - 7.8e-33 113.9 0.0 1.1e-15 58.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KKA02299.1 - 5.4e-18 65.4 0.0 2e-17 63.6 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KKA02299.1 - 9.6e-07 28.6 0.3 6.1e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KKA02299.1 - 2.4e-06 27.6 0.0 0.00042 20.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KKA02299.1 - 5.2e-06 27.0 0.0 0.025 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KKA02299.1 - 6.8e-05 22.4 0.2 0.061 12.8 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KKA02299.1 - 8.9e-05 22.9 0.6 0.0013 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KKA02299.1 - 0.00018 21.7 0.0 0.019 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKA02299.1 - 0.00036 20.2 3.5 0.0058 16.3 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KKA02299.1 - 0.00046 20.1 0.0 1.4 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKA02299.1 - 0.0006 20.4 1.0 0.07 13.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKA02299.1 - 0.017 15.4 2.7 0.57 10.4 0.1 3.6 4 0 0 4 4 3 0 AAA domain dNK PF01712.19 KKA02299.1 - 0.085 12.7 0.1 8.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase SLAM PF06214.11 KKA02299.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein MMR_HSR1 PF01926.23 KKA02299.1 - 0.19 11.8 0.7 23 5.1 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KKA02299.1 - 0.21 11.3 1.0 3.7 7.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKA02299.1 - 0.21 11.5 2.7 4.2 7.2 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 KKA02299.1 - 0.22 11.8 2.4 2.8 8.1 0.3 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KKA02299.1 - 0.58 9.7 4.4 0.67 9.5 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Transp_cyt_pur PF02133.15 KKA02301.1 - 6.7e-61 206.4 39.1 8.1e-61 206.1 39.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mito_carr PF00153.27 KKA02302.1 - 1.2e-32 111.7 5.8 1e-10 41.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB PF00651.31 KKA02302.1 - 0.071 13.4 1.0 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 BTB/POZ domain UvrD-helicase PF00580.21 KKA02303.1 - 8.9e-56 189.7 1.1 8.9e-56 189.7 1.1 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KKA02303.1 - 4.4e-46 157.9 6.7 1.2e-45 156.4 6.7 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KKA02303.1 - 1.1e-25 90.7 0.0 2.1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KKA02303.1 - 2.6e-10 40.0 0.0 0.00033 20.4 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KKA02303.1 - 6.6e-05 22.8 0.5 1.9 8.2 0.0 4.2 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KKA02303.1 - 0.00022 21.0 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KKA02303.1 - 0.017 15.0 0.0 0.017 15.0 0.0 2.9 3 1 0 3 3 3 0 AAA domain CBP_BcsQ PF06564.12 KKA02303.1 - 0.038 13.5 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ PBECR3 PF18812.1 KKA02303.1 - 0.14 12.1 6.8 0.12 12.3 3.8 2.5 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 GWT1 PF06423.12 KKA02304.1 - 1.7e-32 112.6 2.8 1.7e-32 112.6 2.8 3.1 3 1 0 3 3 3 1 GWT1 DUF4818 PF16089.5 KKA02304.1 - 0.036 14.5 0.0 0.16 12.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) DUF998 PF06197.13 KKA02304.1 - 0.089 12.4 2.1 0.32 10.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Arrestin_C PF02752.22 KKA02305.1 - 5.1e-10 39.9 2.5 1.1e-09 38.9 0.9 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKA02305.1 - 2.6e-05 24.3 0.0 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.15 KKA02306.1 - 1.9e-21 76.5 19.0 1.9e-21 76.5 19.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit OST_P2 PF18235.1 KKA02306.1 - 0.15 12.0 1.4 0.64 10.0 0.0 2.9 2 1 1 3 3 3 0 Oligosaccharyltransferase Peripheral 2 domain Peptidase_M28 PF04389.17 KKA02307.1 - 8.6e-36 123.5 0.0 2.4e-35 122.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.15 KKA02307.1 - 0.0051 16.3 0.1 0.0073 15.8 0.1 1.4 1 0 0 1 1 1 1 Nicastrin OPT PF03169.15 KKA02308.1 - 9.6e-153 510.1 46.4 1.1e-152 509.9 46.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KKA02309.1 - 6.8e-154 513.9 49.0 7.8e-154 513.7 49.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KKA02310.1 - 1.7e-156 522.4 48.2 2e-156 522.2 48.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KKA02311.1 - 2.7e-152 508.6 48.0 3.1e-152 508.4 48.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 KKA02312.1 - 2.8e-68 230.1 0.4 5.4e-68 229.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02312.1 - 1.2e-39 136.2 0.0 2e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase IL12 PF03039.14 KKA02312.1 - 0.019 14.3 0.1 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Kdo PF06293.14 KKA02312.1 - 0.045 13.1 0.9 0.091 12.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKA02312.1 - 0.34 10.2 7.3 0.18 11.1 0.3 3.2 2 1 1 3 3 3 0 Kinase-like DUF3797 PF12677.7 KKA02313.1 - 0.067 13.1 0.0 0.067 13.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) WD40 PF00400.32 KKA02313.1 - 0.071 14.0 0.6 41 5.3 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat CBFD_NFYB_HMF PF00808.23 KKA02314.1 - 0.0013 18.9 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IDEAL PF08858.10 KKA02314.1 - 0.16 11.7 2.9 1 9.2 1.6 2.3 2 0 0 2 2 2 0 IDEAL domain TAFII28 PF04719.14 KKA02314.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region MPM1 PF17234.2 KKA02315.1 - 4.5e-28 98.6 13.3 4.5e-28 98.6 13.3 2.2 2 1 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 ANTH PF07651.16 KKA02315.1 - 0.13 11.2 3.5 0.099 11.6 2.0 1.6 2 0 0 2 2 2 0 ANTH domain DUF234 PF03008.14 KKA02315.1 - 0.34 11.4 7.4 5.2 7.6 0.0 3.5 3 1 0 3 3 3 0 Archaea bacterial proteins of unknown function Pet191_N PF10203.9 KKA02316.1 - 2.3e-18 66.3 2.7 3.1e-18 65.8 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KKA02316.1 - 0.28 11.4 4.0 0.52 10.5 0.2 2.3 2 0 0 2 2 2 0 CHCH domain SNF2_N PF00176.23 KKA02317.1 - 8.4e-69 231.9 0.4 8.4e-69 231.9 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA02317.1 - 1e-20 74.1 0.0 1e-20 74.1 0.0 3.8 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02317.1 - 8.2e-11 42.2 0.3 8.2e-11 42.2 0.3 3.5 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKA02317.1 - 0.0035 17.1 0.8 0.083 12.7 0.1 2.9 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_11 PF13086.6 KKA02317.1 - 0.022 14.6 0.2 0.022 14.6 0.2 4.0 4 1 0 4 4 4 0 AAA domain Rieske PF00355.26 KKA02318.1 - 4e-11 42.7 0.0 7.1e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KKA02318.1 - 3.3e-10 40.3 0.8 5.3e-10 39.6 0.1 1.7 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region HECT PF00632.25 KKA02319.1 - 9e-41 140.3 9.6 9e-41 140.3 9.6 3.6 2 2 1 3 3 3 1 HECT-domain (ubiquitin-transferase) FYVE_2 PF02318.16 KKA02319.1 - 0.0086 16.3 1.1 0.039 14.2 1.1 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger NST1 PF13945.6 KKA02319.1 - 0.028 14.6 0.7 8.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Salt tolerance down-regulator ADD_DNMT3 PF17980.1 KKA02319.1 - 0.095 12.7 1.4 1 9.4 0.3 2.6 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Ribosomal_L7Ae PF01248.26 KKA02320.1 - 4e-27 93.8 0.1 4.8e-27 93.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KKA02320.1 - 0.00055 19.8 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KKA02320.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Adenosine_kin PF04008.14 KKA02320.1 - 0.021 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase DUF2229 PF09989.9 KKA02320.1 - 0.024 14.3 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) SAM_KSR1 PF13543.6 KKA02321.1 - 0.026 14.7 3.6 0.058 13.5 3.6 1.8 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 UvrD-helicase PF00580.21 KKA02321.1 - 0.034 13.7 9.1 0.036 13.6 9.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Z1 PF10593.9 KKA02321.1 - 0.08 12.4 2.1 0.082 12.4 1.4 1.3 1 1 0 1 1 1 0 Z1 domain FAD_SOX PF18371.1 KKA02321.1 - 0.76 10.2 4.9 0.7 10.3 1.3 2.3 1 1 2 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Ribosomal_S8 PF00410.19 KKA02321.1 - 0.93 9.4 5.1 1.6 8.7 5.1 1.6 1 1 0 1 1 1 0 Ribosomal protein S8 Pyr_redox_2 PF07992.14 KKA02322.1 - 3.9e-37 128.1 0.0 5.8e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKA02322.1 - 3.3e-12 46.8 0.3 1.1e-09 38.7 0.2 3.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 KKA02323.1 - 5.2e-41 138.3 10.2 2.2e-14 53.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKA02323.1 - 0.00029 20.7 0.0 5.3 7.0 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KKA02323.1 - 0.0037 17.3 1.0 6 7.0 0.0 3.6 4 0 0 4 4 4 2 RNA binding motif DUF4523 PF15023.6 KKA02323.1 - 0.042 13.7 0.9 7.9 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) GTP_EFTU PF00009.27 KKA02324.1 - 1.6e-25 89.8 4.9 1.5e-23 83.4 4.9 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKA02324.1 - 2.3e-25 88.7 2.0 4.4e-25 87.8 0.5 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KKA02324.1 - 5.8e-09 36.0 0.2 1.6e-08 34.7 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KKA02324.1 - 1.1e-05 24.9 0.3 4.4e-05 23.0 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKA02324.1 - 0.00037 20.1 0.3 0.028 14.0 0.0 2.4 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 KKA02324.1 - 0.00038 20.0 0.6 0.0013 18.3 0.6 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KKA02324.1 - 0.0028 17.1 0.3 0.0072 15.8 0.3 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KKA02324.1 - 0.0039 17.3 1.0 0.4 10.7 0.1 3.6 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 KKA02324.1 - 0.013 15.7 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IF2_N PF04760.15 KKA02324.1 - 0.074 12.9 0.0 0.26 11.1 0.0 2.1 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region PDCD2_C PF04194.13 KKA02325.1 - 1e-28 100.6 1.4 1.3e-28 100.2 0.1 1.8 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain ABC_tran PF00005.27 KKA02326.1 - 1.2e-45 155.4 14.0 1.1e-23 84.3 0.0 4.5 4 1 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KKA02326.1 - 4.3e-19 68.3 9.5 4.3e-19 68.3 9.5 3.3 4 1 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KKA02326.1 - 2.1e-12 47.5 17.6 0.0037 17.1 0.3 5.1 3 2 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKA02326.1 - 6e-07 30.0 0.0 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKA02326.1 - 1.1e-06 29.0 0.0 0.0036 17.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKA02326.1 - 1.4e-06 28.4 0.6 0.017 15.0 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KKA02326.1 - 1.7e-06 28.1 0.1 0.03 14.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KKA02326.1 - 7.8e-06 26.2 0.0 0.12 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KKA02326.1 - 1.4e-05 25.1 5.3 0.032 14.3 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_29 PF13555.6 KKA02326.1 - 1.5e-05 24.7 2.4 0.1 12.3 0.2 3.2 2 1 1 3 3 3 2 P-loop containing region of AAA domain NACHT PF05729.12 KKA02326.1 - 2e-05 24.6 0.0 0.044 13.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KKA02326.1 - 2.3e-05 24.6 0.2 0.14 12.4 0.0 3.5 3 2 0 3 3 3 2 AAA domain NB-ARC PF00931.22 KKA02326.1 - 3e-05 23.3 0.1 0.0074 15.5 0.0 2.9 3 1 0 3 3 3 1 NB-ARC domain AAA_23 PF13476.6 KKA02326.1 - 4.1e-05 24.2 34.2 0.069 13.7 0.0 5.2 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 KKA02326.1 - 0.00012 22.4 0.2 1.6 9.2 0.0 3.6 3 0 0 3 3 3 2 RNA helicase MeaB PF03308.16 KKA02326.1 - 0.00018 20.6 0.0 0.28 10.1 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KKA02326.1 - 0.00027 21.4 2.0 0.37 11.2 0.0 3.8 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KKA02326.1 - 0.00032 20.2 11.7 0.039 13.4 0.3 5.0 4 2 1 5 5 5 2 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 KKA02326.1 - 0.0013 18.4 0.1 1.8 8.2 0.0 2.6 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KKA02326.1 - 0.0018 17.8 0.1 1.2 8.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 KKA02326.1 - 0.0027 17.3 0.1 1.4 8.4 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KKA02326.1 - 0.0029 18.1 2.2 3.1 8.3 0.0 3.6 3 1 0 3 3 3 1 AAA domain FeoB_N PF02421.18 KKA02326.1 - 0.0032 17.0 0.0 0.43 10.1 0.0 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KKA02326.1 - 0.0034 16.9 0.1 0.077 12.4 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family SRP54 PF00448.22 KKA02326.1 - 0.0041 16.8 0.1 2 8.0 0.1 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKA02326.1 - 0.0061 16.3 0.0 5.3 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KKA02326.1 - 0.0095 16.0 0.0 0.0095 16.0 0.0 4.1 4 1 0 4 4 4 1 Dynamin family MobB PF03205.14 KKA02326.1 - 0.0095 15.8 0.2 0.24 11.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 KKA02326.1 - 0.015 15.6 0.0 9.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKA02326.1 - 0.017 14.7 1.5 6.5 6.3 0.0 3.7 4 0 0 4 4 4 0 Ras family PduV-EutP PF10662.9 KKA02326.1 - 0.022 14.5 0.2 7.7 6.3 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KKA02326.1 - 0.031 14.0 0.0 1.6 8.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KKA02326.1 - 0.031 14.3 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KKA02326.1 - 0.04 14.3 0.0 0.97 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KKA02326.1 - 0.053 13.2 0.0 0.053 13.2 0.0 5.6 4 2 2 6 6 5 0 AAA ATPase domain TsaE PF02367.17 KKA02326.1 - 0.07 13.1 0.5 11 6.1 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KKA02326.1 - 0.071 12.8 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 KKA02326.1 - 0.09 12.9 0.0 0.09 12.9 0.0 4.9 4 2 1 5 5 5 0 Helicase HerA, central domain T2SSE PF00437.20 KKA02326.1 - 0.094 11.8 0.1 3.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_17 PF13207.6 KKA02326.1 - 0.3 11.5 3.9 16 5.9 0.0 4.3 4 1 1 5 5 5 0 AAA domain DUF4667 PF15700.5 KKA02326.1 - 6.2 6.8 10.6 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) RNB PF00773.19 KKA02327.1 - 4.5e-99 331.9 0.0 4.5e-99 331.9 0.0 2.1 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 KKA02327.1 - 4.4e-49 166.0 2.0 1.2e-48 164.5 2.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KKA02327.1 - 1.4e-29 101.8 1.1 1.4e-29 101.8 1.1 2.7 3 0 0 3 3 3 1 S1 domain OB_Dis3 PF17849.1 KKA02327.1 - 9.1e-15 54.5 0.0 2.3e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KKA02327.1 - 4.2e-10 40.0 2.4 1.6e-09 38.2 2.4 2.1 1 0 0 1 1 1 1 PIN domain Dis3l2_C_term PF17877.1 KKA02327.1 - 0.0001 22.6 1.2 0.00029 21.1 0.1 2.3 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KKA02327.1 - 0.01 16.0 1.0 0.26 11.5 0.0 3.4 3 0 0 3 3 3 0 Cold shock domain IBR PF01485.21 KKA02328.1 - 1.6e-14 53.8 39.5 3e-08 33.8 10.5 4.2 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Actin PF00022.19 KKA02329.1 - 2.6e-79 266.7 0.0 3.9e-79 266.2 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKA02329.1 - 0.0082 15.0 0.2 0.023 13.5 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Actin_micro PF17003.5 KKA02329.1 - 0.009 15.2 0.2 0.013 14.7 0.2 1.3 1 0 0 1 1 1 1 Putative actin-like family SET PF00856.28 KKA02330.1 - 2.3e-08 34.6 7.3 2.9e-08 34.3 1.5 3.5 2 1 0 2 2 2 1 SET domain Methyltransf_25 PF13649.6 KKA02331.1 - 1e-07 32.5 0.0 3.9e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKA02331.1 - 1.7e-07 31.0 0.0 3.7e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KKA02331.1 - 1.1e-06 28.6 0.0 2.8e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA02331.1 - 1.9e-05 25.2 0.0 5.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKA02331.1 - 6.5e-05 22.9 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA02331.1 - 8.9e-05 23.2 0.1 0.00039 21.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA02331.1 - 0.00012 22.0 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKA02331.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 KKA02331.1 - 0.0013 18.6 0.4 0.0022 17.9 0.4 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 KKA02331.1 - 0.0034 17.1 0.2 0.0065 16.3 0.2 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KKA02331.1 - 0.0043 16.0 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 KKA02331.1 - 0.0078 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KKA02331.1 - 0.014 15.1 0.5 0.048 13.4 0.1 1.8 1 1 1 2 2 2 0 Lysine methyltransferase Met_10 PF02475.16 KKA02331.1 - 0.019 14.7 0.2 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 Met-10+ like-protein GidB PF02527.15 KKA02331.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.18 KKA02331.1 - 0.04 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Rsm22 PF09243.10 KKA02331.1 - 0.056 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 KKA02331.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CAP PF00188.26 KKA02332.1 - 2.4e-20 73.7 1.3 2.4e-20 73.7 1.3 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PRCC PF10253.9 KKA02332.1 - 3.9 8.2 16.3 7 7.4 16.3 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.16 KKA02333.1 - 2.3e-12 46.5 12.2 2.3e-06 26.8 5.5 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 KKA02334.1 - 6.1e-86 288.5 40.5 1.4e-45 156.1 20.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKA02334.1 - 5.1e-48 163.1 5.9 9.3e-24 84.5 0.1 3.3 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.19 KKA02334.1 - 8.3e-12 45.0 19.7 4.5e-06 26.3 0.5 5.0 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKA02334.1 - 2.3e-07 30.5 0.8 0.004 16.9 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KKA02334.1 - 5.3e-07 30.3 0.4 0.017 15.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KKA02334.1 - 8.3e-07 29.1 9.0 0.004 17.1 0.1 3.3 4 0 0 4 4 3 2 RsgA GTPase AAA_21 PF13304.6 KKA02334.1 - 8.9e-07 29.0 10.4 0.069 12.9 0.1 5.1 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKA02334.1 - 1.8e-06 28.2 0.1 0.037 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKA02334.1 - 1e-05 26.0 0.0 0.094 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KKA02334.1 - 1.1e-05 25.5 0.5 0.0064 16.4 0.1 3.2 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KKA02334.1 - 3.2e-05 23.9 0.1 0.21 11.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KKA02334.1 - 7.2e-05 22.8 0.2 0.32 11.1 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKA02334.1 - 0.00015 22.1 0.0 0.96 9.9 0.0 3.5 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KKA02334.1 - 0.00093 19.6 0.4 0.37 11.2 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKA02334.1 - 0.00094 19.4 0.0 0.92 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KKA02334.1 - 0.00095 19.7 3.6 0.00095 19.7 3.6 4.5 4 1 0 4 4 4 2 AAA domain AAA_24 PF13479.6 KKA02334.1 - 0.0017 18.1 3.0 0.087 12.5 1.8 2.9 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KKA02334.1 - 0.0026 17.7 0.4 2.6 7.9 0.0 3.0 3 0 0 3 3 3 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KKA02334.1 - 0.0037 16.6 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KKA02334.1 - 0.0038 17.0 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKA02334.1 - 0.0041 16.3 0.1 0.32 10.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PRK PF00485.18 KKA02334.1 - 0.025 14.3 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KKA02334.1 - 0.027 14.4 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KKA02334.1 - 0.058 13.0 0.0 0.97 9.0 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KKA02334.1 - 0.067 12.7 5.5 5.9 6.4 0.1 3.7 3 1 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 KKA02334.1 - 0.089 12.4 0.0 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KKA02334.1 - 0.15 11.4 0.4 2.7 7.3 0.1 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF3987 PF13148.6 KKA02334.1 - 0.18 10.8 0.0 0.5 9.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PEMT PF04191.13 KKA02335.1 - 2.9e-28 98.4 0.6 5e-28 97.6 0.3 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase EMC3_TMCO1 PF01956.16 KKA02336.1 - 3e-33 114.9 2.3 2.1e-32 112.2 2.3 2.0 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ATP_bind_1 PF03029.17 KKA02337.1 - 1.4e-76 257.4 1.9 1.7e-76 257.2 0.1 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KKA02337.1 - 6.3e-05 22.6 0.1 0.0011 18.6 0.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KKA02337.1 - 0.00014 21.0 0.1 0.4 9.6 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KKA02337.1 - 0.0002 21.1 0.1 0.00079 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKA02337.1 - 0.00026 21.1 0.0 0.0022 18.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KKA02337.1 - 0.00027 21.1 0.0 0.00063 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KKA02337.1 - 0.00043 20.1 0.1 0.024 14.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KKA02337.1 - 0.00056 20.2 0.0 0.0023 18.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 KKA02337.1 - 0.0007 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 KKA02337.1 - 0.00072 19.1 0.0 0.021 14.3 0.0 2.5 3 0 0 3 3 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 KKA02337.1 - 0.004 17.7 0.8 0.079 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKA02337.1 - 0.0047 16.5 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PRK PF00485.18 KKA02337.1 - 0.0048 16.7 0.0 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KKA02337.1 - 0.0071 16.3 0.1 3.6 7.5 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase SRP54 PF00448.22 KKA02337.1 - 0.0082 15.8 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain KAP_NTPase PF07693.14 KKA02337.1 - 0.0096 15.2 0.5 0.078 12.2 0.6 2.1 1 1 0 1 1 1 1 KAP family P-loop domain Roc PF08477.13 KKA02337.1 - 0.011 15.9 0.0 0.66 10.2 0.0 2.5 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KKA02337.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKA02337.1 - 0.016 15.6 0.3 1.3 9.5 0.0 3.2 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.22 KKA02337.1 - 0.018 14.2 0.2 0.058 12.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 KKA02337.1 - 0.02 14.7 0.0 0.33 10.7 0.0 2.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KKA02337.1 - 0.03 14.7 0.0 0.093 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KKA02337.1 - 0.072 12.7 0.1 2.2 7.8 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KKA02337.1 - 0.093 12.2 0.1 0.74 9.2 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family DUF87 PF01935.17 KKA02337.1 - 0.17 11.9 5.2 3.5 7.7 0.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain Thymidylate_kin PF02223.17 KKA02337.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.4 3 0 0 3 3 2 0 Thymidylate kinase SRPRB PF09439.10 KKA02337.1 - 0.55 9.6 0.0 0.55 9.6 0.0 2.6 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit MPM1 PF17234.2 KKA02337.1 - 1.2 9.3 8.7 1.2 9.4 7.6 1.4 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 G-alpha PF00503.20 KKA02337.1 - 1.5 7.9 0.0 1.5 7.9 0.0 3.4 3 1 1 4 4 4 0 G-protein alpha subunit AAA_17 PF13207.6 KKA02337.1 - 3 8.3 0.0 3 8.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain CM_2 PF01817.21 KKA02337.1 - 3.4 8.1 5.8 3.8 7.9 2.7 2.4 2 0 0 2 2 2 0 Chorismate mutase type II EMC3_TMCO1 PF01956.16 KKA02337.1 - 5.5 6.7 8.1 3.4 7.4 2.9 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PAC2 PF09754.9 KKA02338.1 - 5.5e-07 29.8 0.0 1.5e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 PAC2 family SAC3_GANP PF03399.16 KKA02338.1 - 0.054 12.9 0.6 0.082 12.3 0.6 1.2 1 0 0 1 1 1 0 SAC3/GANP family Ham1p_like PF01725.16 KKA02339.1 - 8.2e-47 159.5 0.2 9.1e-47 159.4 0.2 1.0 1 0 0 1 1 1 1 Ham1 family Maf PF02545.14 KKA02339.1 - 0.0014 18.5 0.1 0.0019 18.1 0.1 1.1 1 0 0 1 1 1 1 Maf-like protein Xpo1 PF08389.12 KKA02340.1 - 1.3e-22 80.5 8.6 1.3e-22 80.5 8.6 3.8 4 0 0 4 4 4 1 Exportin 1-like protein AC_N PF16214.5 KKA02341.1 - 0.077 12.1 0.4 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DNA_pol3_delta2 PF13177.6 KKA02342.1 - 2.7e-13 50.0 6.2 1.4e-12 47.7 0.7 3.1 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KKA02342.1 - 4.9e-13 49.6 0.0 2.3e-12 47.5 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKA02342.1 - 5.8e-11 42.7 1.2 9.6e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain Rep_fac_C PF08542.11 KKA02342.1 - 4.3e-10 39.9 0.2 1.1e-09 38.5 0.1 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KKA02342.1 - 1.5e-06 28.5 0.1 9.1e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KKA02342.1 - 1.2e-05 25.2 0.0 0.00025 20.9 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKA02342.1 - 1.6e-05 25.3 0.1 0.00063 20.2 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KKA02342.1 - 1.9e-05 24.8 2.2 5.3e-05 23.3 0.1 2.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KKA02342.1 - 0.00032 20.5 0.1 0.00091 19.0 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 KKA02342.1 - 0.0012 19.1 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 KKA02342.1 - 0.0046 16.7 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKA02342.1 - 0.0048 16.1 0.0 0.0094 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KKA02342.1 - 0.0085 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 KKA02342.1 - 0.0096 16.4 5.7 0.01 16.4 3.6 2.1 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KKA02342.1 - 0.013 14.9 0.1 0.43 10.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF1609 PF07753.11 KKA02342.1 - 0.025 14.1 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) ATPase_2 PF01637.18 KKA02342.1 - 0.038 13.9 3.1 1.8 8.4 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KKA02342.1 - 0.058 12.8 0.0 0.99 8.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KKA02342.1 - 0.062 13.4 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Torsin RNA_helicase PF00910.22 KKA02342.1 - 0.066 13.6 0.2 0.49 10.8 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KKA02342.1 - 0.074 13.1 0.5 1.2 9.1 0.2 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KKA02342.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PC_rep PF01851.22 KKA02342.1 - 0.12 12.9 0.2 25 5.5 0.0 3.3 3 0 0 3 3 3 0 Proteasome/cyclosome repeat AAA_19 PF13245.6 KKA02342.1 - 0.13 12.6 0.3 1.1 9.5 0.1 2.2 1 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KKA02342.1 - 0.18 10.8 0.0 0.46 9.4 0.0 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 KKA02342.1 - 0.18 11.6 1.8 2.4 7.9 0.0 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase Peripla_BP_2 PF01497.18 KKA02343.1 - 0.057 13.0 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Yae1_N PF09811.9 KKA02343.1 - 0.076 12.7 0.4 0.59 9.9 0.1 2.1 2 0 0 2 2 2 0 Essential protein Yae1, N terminal TFIID-18kDa PF02269.16 KKA02343.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit FAT PF02259.23 KKA02344.1 - 4.4e-126 420.8 5.2 4.4e-126 420.8 5.2 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KKA02344.1 - 1.7e-70 237.7 0.1 1.7e-70 237.7 0.1 2.9 4 0 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KKA02344.1 - 3.9e-57 192.7 21.1 9.4e-57 191.4 2.3 6.0 6 0 0 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KKA02344.1 - 9.5e-42 141.4 5.0 1.4e-41 140.9 1.1 3.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KKA02344.1 - 1.6e-17 63.0 0.3 4.1e-17 61.7 0.3 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KKA02344.1 - 5.8e-09 36.2 0.0 0.0079 16.6 0.0 6.0 6 2 0 6 6 6 2 HEAT repeats HEAT PF02985.22 KKA02344.1 - 7.3e-09 35.1 0.2 0.0056 16.8 0.0 6.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KKA02344.1 - 5.9e-07 29.9 0.0 4.5 7.9 0.0 6.7 6 1 3 9 9 6 3 HEAT-like repeat ATP13 PF12921.7 KKA02344.1 - 0.01 15.7 0.1 0.089 12.7 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase expression Imm30 PF15565.6 KKA02344.1 - 0.14 12.2 2.3 0.71 10.0 0.2 3.5 2 0 0 2 2 2 0 Immunity protein 30 Vac14_Fab1_bd PF12755.7 KKA02344.1 - 0.29 11.8 4.4 11 6.7 0.0 4.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Actin PF00022.19 KKA02345.1 - 1.7e-92 310.1 0.0 4.7e-90 302.1 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKA02345.1 - 1.2e-05 24.4 0.0 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KKA02345.1 - 0.00058 20.2 0.0 0.0045 17.4 0.0 2.3 2 1 0 2 2 2 1 Cell division protein FtsA ANAPC9 PF12856.7 KKA02345.1 - 0.061 13.5 0.4 0.15 12.2 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Cpn60_TCP1 PF00118.24 KKA02346.1 - 5.2e-155 516.8 7.8 5.9e-155 516.6 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_ATPase PF13246.6 KKA02346.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) TFIIS_C PF01096.18 KKA02347.1 - 1.8e-13 50.1 2.1 1.8e-13 50.1 2.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 KKA02347.1 - 0.00024 20.7 0.5 0.00024 20.7 0.5 3.4 3 1 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_9 PF14369.6 KKA02347.1 - 0.011 15.9 9.7 4.4 7.6 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon zinc_ribbon_4 PF13717.6 KKA02347.1 - 0.025 14.5 11.1 4 7.4 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 KKA02347.1 - 0.029 14.6 9.2 11 6.2 0.3 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-BED PF02892.15 KKA02347.1 - 0.055 13.5 2.7 0.055 13.5 2.7 2.0 2 0 0 2 2 2 0 BED zinc finger Peptidase_M9 PF01752.17 KKA02347.1 - 0.1 11.9 0.7 0.12 11.6 0.7 1.1 1 0 0 1 1 1 0 Collagenase zf_C2H2_10 PF18414.1 KKA02347.1 - 0.13 11.8 3.0 5.1 6.7 0.7 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger DZR PF12773.7 KKA02347.1 - 0.21 11.7 14.1 0.64 10.1 2.5 3.1 1 1 1 2 2 2 0 Double zinc ribbon Nop10p PF04135.12 KKA02347.1 - 0.46 10.6 2.5 1.1 9.4 0.2 2.5 1 1 1 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Zn_Tnp_IS1 PF03811.13 KKA02347.1 - 0.48 10.2 4.2 15 5.4 0.0 3.1 3 0 0 3 3 3 0 InsA N-terminal domain zf-C4_Topoisom PF01396.19 KKA02347.1 - 0.62 9.9 9.5 3.3 7.6 0.1 3.8 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Tmemb_9 PF05434.11 KKA02347.1 - 1.8 8.4 9.2 0.3 11.0 1.2 2.4 1 1 2 3 3 3 0 TMEM9 Terminase_GpA PF05876.12 KKA02347.1 - 2.2 6.8 5.3 3.3 6.2 0.2 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-TFIIB PF13453.6 KKA02347.1 - 3.9 6.9 10.9 0.13 11.6 2.6 2.7 3 1 0 3 3 3 0 Transcription factor zinc-finger HypA PF01155.19 KKA02347.1 - 4.9 7.2 9.0 94 3.1 9.0 2.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2387 PF09526.10 KKA02347.1 - 5.1 7.3 8.9 0.52 10.5 0.4 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc_ribbon_15 PF17032.5 KKA02347.1 - 6.7 7.5 15.6 1.8 9.4 3.9 2.9 1 1 1 2 2 2 0 zinc-ribbon family Ofd1_CTDD PF10637.9 KKA02348.1 - 1.6e-64 217.8 6.8 2e-64 217.4 5.2 1.9 2 1 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KKA02348.1 - 1.4e-28 99.4 0.1 1.5e-25 89.6 0.1 2.8 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KKA02348.1 - 4.9e-15 56.2 0.1 8.7e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KKA02348.1 - 0.012 16.1 0.0 0.035 14.6 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RNase_H2-Ydr279 PF09468.10 KKA02348.1 - 0.17 12.0 4.8 0.21 11.8 2.4 2.3 2 1 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Sdh5 PF03937.16 KKA02348.1 - 0.69 9.9 3.9 56 3.8 0.0 3.9 4 0 0 4 4 4 0 Flavinator of succinate dehydrogenase BAR_2 PF10455.9 KKA02349.1 - 2.3e-24 86.0 23.1 3.1e-24 85.6 23.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKA02349.1 - 4.9e-07 29.7 14.5 8.3e-06 25.6 14.0 2.4 1 1 0 1 1 1 1 BAR domain Cep57_CLD_2 PF14197.6 KKA02349.1 - 0.048 13.7 2.4 2 8.6 0.4 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ApoC-I PF04691.12 KKA02349.1 - 1.4 8.9 9.5 1.1 9.2 3.2 3.1 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) Phasin PF05597.11 KKA02349.1 - 4.3 7.4 5.3 1.9 8.5 0.6 2.8 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Exo_endo_phos PF03372.23 KKA02350.1 - 0.0069 15.9 0.0 0.045 13.3 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KKA02350.1 - 0.44 10.4 6.5 0.16 11.8 2.6 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase BCDHK_Adom3 PF10436.9 KKA02351.1 - 1.6e-11 44.3 2.6 2.5e-11 43.7 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKA02351.1 - 1.3e-10 41.8 0.1 2.3e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKA02351.1 - 0.00048 20.0 1.4 0.00066 19.5 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKA02351.1 - 0.0019 18.2 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain NAD_binding_1 PF00175.21 KKA02352.1 - 8.5e-26 90.7 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKA02352.1 - 2e-25 89.0 0.0 3.5e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKA02352.1 - 1.2e-10 41.7 0.1 3.4e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AA_kinase PF00696.28 KKA02353.1 - 5.5e-39 134.2 0.0 1e-38 133.3 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KKA02353.1 - 6.3e-11 41.9 2.8 2.2e-08 33.8 0.5 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KKA02353.1 - 1.1e-10 41.0 1.0 1.6e-05 24.5 0.2 3.0 3 0 0 3 3 3 2 ACT domain DUF4091 PF13320.6 KKA02353.1 - 0.026 14.7 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) DotA PF11388.8 KKA02353.1 - 0.17 12.1 0.4 0.49 10.6 0.4 1.8 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Cyt-b5 PF00173.28 KKA02354.1 - 2.7e-11 43.4 0.0 4.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUDIX PF00293.28 KKA02355.1 - 1.9e-10 40.9 0.0 3.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_2 PF12756.7 KKA02355.1 - 0.26 11.6 2.6 3.8 7.9 0.3 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ArfGap PF01412.18 KKA02356.1 - 2.8e-32 111.2 0.4 2.8e-32 111.2 0.4 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GST_N PF02798.20 KKA02357.1 - 5.3e-06 26.7 0.1 4.3e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKA02357.1 - 0.0096 16.1 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKA02358.1 - 4.7e-07 29.9 0.1 8.9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKA02358.1 - 3.1e-05 24.2 0.0 7.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKA02358.1 - 0.00098 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF692 PF05114.13 KKA02358.1 - 0.02 14.1 0.1 0.039 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF692) GST_C_2 PF13410.6 KKA02358.1 - 0.037 14.1 0.4 0.11 12.6 0.2 1.8 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Sgf11 PF08209.11 KKA02359.1 - 1e-12 47.4 0.2 1.5e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) PRP21_like_P PF12230.8 KKA02359.1 - 0.025 14.5 0.7 0.025 14.5 0.7 2.5 1 1 2 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Elf1 PF05129.13 KKA02359.1 - 0.1 12.7 2.2 2.9 8.0 0.5 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_2 PF13639.6 KKA02360.1 - 0.00096 19.4 0.1 0.0034 17.7 0.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKA02360.1 - 0.0021 18.0 0.1 0.0051 16.8 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 KKA02360.1 - 0.0078 16.0 0.1 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 KKA02360.1 - 0.0088 15.4 0.6 0.03 13.7 0.1 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger Skp1_POZ PF03931.15 KKA02361.1 - 0.0076 16.4 0.4 0.023 14.8 0.4 1.8 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Vps16_N PF04841.13 KKA02362.1 - 2.3e-28 99.1 5.3 1.3e-27 96.6 3.2 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 KKA02362.1 - 1e-10 41.2 7.4 1e-10 41.2 7.4 2.4 3 0 0 3 3 3 1 Vps16, C-terminal region RRM_1 PF00076.22 KKA02363.1 - 6.5e-56 186.1 0.6 2.5e-17 62.5 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKA02363.1 - 7.1e-08 32.5 0.1 0.061 13.5 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif RRM_Rrp7 PF17799.1 KKA02363.1 - 5.7e-05 23.0 2.8 0.89 9.3 0.0 4.6 3 2 2 5 5 5 2 Rrp7 RRM-like N-terminal domain Pkinase PF00069.25 KKA02364.1 - 1.5e-56 191.7 3.5 1.1e-55 188.9 0.2 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02364.1 - 4.3e-26 91.7 0.1 4.3e-26 91.7 0.1 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Imm7 PF15585.6 KKA02364.1 - 0.065 13.5 0.2 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 7 FLILHELTA PF10306.9 KKA02365.1 - 2.4e-14 53.5 0.1 5e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KKA02365.1 - 4.9e-06 27.0 1.2 9.8e-05 22.8 1.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Hairpins PF04877.12 KKA02365.1 - 0.64 9.6 2.4 0.84 9.2 2.4 1.1 1 0 0 1 1 1 0 HrpZ p450 PF00067.22 KKA02366.1 - 2.6e-42 145.1 1.6 3.5e-42 144.7 1.6 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KKA02367.1 - 9.3e-71 239.0 24.4 1.1e-70 238.8 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA02367.1 - 1.8e-17 63.3 26.5 4.7e-17 62.0 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM43 PF07787.12 KKA02367.1 - 0.21 10.9 1.7 0.46 9.8 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 43 Arf PF00025.21 KKA02369.1 - 5.5e-29 100.8 1.4 5.3e-28 97.6 1.4 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKA02369.1 - 1.6e-12 47.3 2.4 1.2e-06 28.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KKA02369.1 - 4.8e-11 42.9 0.5 2.3e-10 40.7 0.5 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKA02369.1 - 1e-08 35.0 0.1 2.8e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KKA02369.1 - 2e-08 33.9 0.3 1.8e-07 30.8 0.3 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKA02369.1 - 1.1e-06 28.2 0.3 1.7e-06 27.6 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA02369.1 - 0.00047 20.2 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKA02369.1 - 0.00083 18.9 0.1 0.005 16.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SPA PF08616.10 KKA02369.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis AAA_18 PF13238.6 KKA02369.1 - 0.011 16.2 0.2 0.02 15.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KKA02369.1 - 0.02 14.8 0.6 0.039 13.9 0.5 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea YppG PF14179.6 KKA02369.1 - 0.035 14.8 0.0 0.061 14.0 0.0 1.4 1 0 0 1 1 1 0 YppG-like protein AAA_14 PF13173.6 KKA02369.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKA02369.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KKA02369.1 - 0.084 12.3 0.4 0.19 11.2 0.0 1.7 2 1 0 2 2 2 0 Poxvirus A32 protein MeaB PF03308.16 KKA02369.1 - 0.15 11.0 0.1 0.41 9.6 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Alk_phosphatase PF00245.20 KKA02370.1 - 3.5e-88 296.3 0.0 4.4e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KKA02370.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DnaGprimase_HBD PF16730.5 KKA02371.1 - 0.041 14.0 5.2 0.063 13.4 5.2 1.3 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain MIP PF00230.20 KKA02372.1 - 9.2e-42 143.3 15.5 1.1e-41 143.0 15.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sec61_beta PF03911.16 KKA02372.1 - 0.9 9.6 0.0 0.9 9.6 0.0 4.1 3 1 1 4 4 4 0 Sec61beta family Tfb2 PF03849.14 KKA02373.1 - 1.7e-100 336.4 12.1 8.1e-100 334.2 12.1 1.9 1 1 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KKA02373.1 - 5.9e-22 77.9 0.7 1.9e-21 76.2 0.3 2.2 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KKA02373.1 - 1.5e-05 25.1 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA02374.1 - 2.5e-48 164.2 0.0 2.6e-47 160.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02374.1 - 1.5e-31 109.0 0.0 8.6e-31 106.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02374.1 - 0.00033 20.7 0.0 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KKA02374.1 - 0.025 13.4 0.0 0.21 10.3 0.0 2.1 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 KKA02374.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KKA02374.1 - 0.24 11.7 0.4 1.6 9.0 0.4 2.2 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KKA02374.1 - 0.33 10.3 1.5 0.39 10.0 0.0 1.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AA_permease PF00324.21 KKA02375.1 - 3.5e-60 204.0 53.5 4.2e-60 203.7 53.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02375.1 - 1.3e-11 44.0 51.8 2e-11 43.4 51.8 1.2 1 0 0 1 1 1 1 Amino acid permease ETRAMP PF09716.10 KKA02375.1 - 5.2 7.2 10.4 7.5 6.7 0.3 4.5 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Mit_ribos_Mrp51 PF11709.8 KKA02376.1 - 1.6e-17 64.2 2.5 9.7e-11 41.9 1.1 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit DUF2119 PF09892.9 KKA02376.1 - 0.033 13.6 1.6 0.087 12.2 1.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) IGPD PF00475.18 KKA02377.1 - 7.1e-57 191.8 0.2 1.1e-55 187.9 0.2 2.0 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase NUDIX PF00293.28 KKA02378.1 - 1.8e-26 92.7 0.0 4.7e-26 91.4 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Flu_NS2 PF00601.19 KKA02379.1 - 0.19 12.0 11.0 0.071 13.4 3.3 3.4 3 1 0 3 3 3 0 Influenza non-structural protein (NS2) Hist_deacetyl PF00850.19 KKA02381.1 - 6.7e-41 140.7 3.4 4.8e-40 137.9 3.3 2.2 1 1 0 1 1 1 1 Histone deacetylase domain Peptidase_C14 PF00656.22 KKA02382.1 - 1.1e-58 199.1 0.5 1.7e-58 198.5 0.5 1.2 1 0 0 1 1 1 1 Caspase domain PROL5-SMR PF15621.6 KKA02382.1 - 5.3 7.6 18.3 14 6.3 18.3 1.7 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Mur_ligase_M PF08245.12 KKA02383.1 - 0.00091 19.3 4.0 0.0011 19.0 0.4 2.8 2 1 0 2 2 2 1 Mur ligase middle domain DUF5101 PF17031.5 KKA02383.1 - 0.057 13.5 2.1 0.17 12.0 2.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Mur_ligase_C PF02875.21 KKA02383.1 - 0.12 12.6 0.0 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain HP0268 PF18618.1 KKA02383.1 - 1.4 9.4 5.6 1.4 9.4 1.7 2.8 2 0 0 2 2 2 0 HP0268 APG5 PF04106.12 KKA02384.1 - 5.5e-10 39.2 1.2 2.8e-09 36.9 1.2 1.9 1 1 0 1 1 1 1 Autophagy protein Apg5 Methyltransf_12 PF08242.12 KKA02385.1 - 8.9e-16 58.4 0.4 3e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA02385.1 - 3.6e-15 56.2 0.0 6.9e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA02385.1 - 1.1e-12 48.5 0.0 2.6e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA02385.1 - 3.1e-10 40.6 0.0 6.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKA02385.1 - 8.1e-07 29.0 0.4 2.6e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KKA02385.1 - 3.4e-05 23.4 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KKA02385.1 - 0.021 14.7 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF4172 PF13776.6 KKA02385.1 - 0.072 13.4 0.5 0.15 12.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Endotoxin_C2 PF18449.1 KKA02385.1 - 0.11 12.9 3.1 0.24 11.8 0.1 2.5 3 0 0 3 3 3 0 Delta endotoxin Ribosomal_S19 PF00203.21 KKA02386.1 - 0.049 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S19 Acetyltransf_1 PF00583.25 KKA02386.1 - 0.057 13.7 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DnaJ PF00226.31 KKA02387.1 - 5.8e-17 61.6 0.3 5.8e-17 61.6 0.3 3.7 4 0 0 4 4 4 1 DnaJ domain NOA36 PF06524.12 KKA02387.1 - 2.2 7.5 12.3 3.8 6.8 12.3 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4820 PF16091.5 KKA02387.1 - 2.5 7.4 7.6 0.25 10.7 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TAP_C PF03943.13 KKA02388.1 - 2.9e-13 49.2 1.7 2.9e-13 49.2 1.7 2.7 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 KKA02388.1 - 0.00012 21.6 0.4 0.00028 20.4 0.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 KKA02388.1 - 0.0022 17.8 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif LRR_4 PF12799.7 KKA02388.1 - 0.74 10.3 14.7 0.094 13.2 3.6 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) tRNA-synt_2e PF02091.15 KKA02389.1 - 0.031 13.5 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Cyt-b5 PF00173.28 KKA02390.1 - 1.7e-13 50.5 0.1 2.4e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_9 PF08021.11 KKA02390.1 - 0.14 12.3 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain TFR_dimer PF04253.15 KKA02391.1 - 1.7e-23 83.0 0.6 4.2e-23 81.7 0.6 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain EF-hand_7 PF13499.6 KKA02392.1 - 2.1e-20 72.9 8.8 3.5e-10 40.2 4.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KKA02392.1 - 4e-19 66.7 17.4 2.7e-07 29.7 0.3 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KKA02392.1 - 9.1e-17 59.5 12.8 4.8e-07 29.2 0.3 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KKA02392.1 - 7.5e-13 48.1 15.9 1.1e-08 34.7 4.9 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KKA02392.1 - 4.1e-07 29.2 18.2 0.0037 16.7 0.1 4.7 4 1 1 5 5 5 3 EF hand Caleosin PF05042.13 KKA02392.1 - 0.00015 21.8 1.1 0.0052 16.7 0.0 2.9 2 1 1 3 3 3 1 Caleosin related protein EF-hand_4 PF12763.7 KKA02392.1 - 0.00017 21.5 5.6 0.024 14.6 0.0 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KKA02392.1 - 0.0017 18.6 0.3 0.72 10.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KKA02392.1 - 0.0093 16.1 0.9 0.31 11.3 0.3 2.4 2 0 0 2 2 2 1 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 KKA02392.1 - 0.02 15.2 2.6 0.048 14.0 0.4 2.2 2 1 1 3 3 3 0 RNA polymerase Rpb4 DUF4834 PF16118.5 KKA02392.1 - 0.055 14.4 0.5 0.1 13.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SPARC_Ca_bdg PF10591.9 KKA02392.1 - 0.072 13.4 3.4 3.6 7.9 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HTH_40 PF14493.6 KKA02392.1 - 0.095 13.2 0.4 2.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PhetRS_B1 PF18262.1 KKA02392.1 - 0.2 11.9 2.5 3.5 7.9 1.9 2.5 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain AAA PF00004.29 KKA02394.1 - 4.9e-42 143.5 0.0 9.9e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA02394.1 - 4e-10 39.3 0.3 9.9e-10 38.1 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKA02394.1 - 1.3e-07 32.2 0.1 6.3e-05 23.4 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KKA02394.1 - 2.9e-07 30.3 1.0 4.7e-07 29.7 0.2 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KKA02394.1 - 5.8e-07 29.6 0.2 1.5e-05 25.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKA02394.1 - 8.4e-06 26.0 0.0 3e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKA02394.1 - 0.00019 21.2 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KKA02394.1 - 0.00029 20.8 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KKA02394.1 - 0.0039 16.5 1.1 1.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 KKA02394.1 - 0.0064 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KKA02394.1 - 0.0064 16.8 0.3 0.11 12.8 0.1 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKA02394.1 - 0.012 15.0 0.2 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KKA02394.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKA02394.1 - 0.019 15.1 0.0 0.068 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKA02394.1 - 0.019 15.5 0.8 0.16 12.5 0.0 2.9 4 1 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 KKA02394.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KKA02394.1 - 0.022 14.1 2.1 0.091 12.1 0.0 2.8 3 0 0 3 3 3 0 KaiC TIP49 PF06068.13 KKA02394.1 - 0.023 13.9 0.1 0.023 13.9 0.1 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 KKA02394.1 - 0.034 14.2 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KKA02394.1 - 0.041 13.5 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_7 PF12775.7 KKA02394.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region adh_short PF00106.25 KKA02394.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AAA_25 PF13481.6 KKA02394.1 - 0.091 12.3 0.1 0.29 10.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKA02394.1 - 0.2 11.9 0.6 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKA02394.1 - 0.36 10.0 2.7 1.9 7.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KKA02394.1 - 0.39 10.5 6.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF16 PF01519.16 KKA02394.1 - 0.51 10.8 4.8 1.6 9.2 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fucokinase PF07959.12 KKA02395.1 - 1.1e-05 24.5 3.4 0.00028 20.0 3.5 2.4 2 1 0 2 2 2 1 L-fucokinase Hexapep PF00132.24 KKA02395.1 - 1.5e-05 24.5 3.6 0.00076 19.1 3.6 2.8 1 1 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) EDS1_EP PF18117.1 KKA02395.1 - 0.14 12.6 2.5 0.48 10.9 2.5 1.9 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain Hexapep_2 PF14602.6 KKA02395.1 - 3.3 7.6 8.7 1.6 8.6 5.0 2.4 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase UbiA PF01040.18 KKA02396.1 - 2.1e-51 174.6 9.4 3.5e-51 173.9 9.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Corona_NS2 PF04753.12 KKA02396.1 - 0.059 14.0 0.7 7 7.3 0.7 2.6 2 0 0 2 2 2 0 Coronavirus non-structural protein NS2 MitMem_reg PF13012.6 KKA02397.1 - 5.9e-30 104.0 1.3 1.4e-29 102.7 1.3 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKA02397.1 - 1e-24 86.8 0.2 1.8e-24 86.0 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KKA02397.1 - 0.047 13.7 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) TRPM_tetra PF16519.5 KKA02397.1 - 0.26 11.4 7.6 2.1 8.5 0.2 3.9 4 1 1 5 5 5 0 Tetramerisation domain of TRPM ATP_bind_1 PF03029.17 KKA02398.1 - 5.2e-73 245.8 0.1 5.2e-73 245.8 0.1 1.3 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KKA02398.1 - 0.0046 16.0 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KKA02398.1 - 0.0063 16.8 0.0 0.027 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KKA02398.1 - 0.0064 17.0 2.8 0.55 10.8 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 KKA02398.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKA02398.1 - 0.016 15.6 3.4 0.037 14.4 0.1 2.9 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KKA02398.1 - 0.019 15.1 0.0 3.6 7.7 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase KTI12 PF08433.10 KKA02398.1 - 0.019 14.4 0.0 0.073 12.5 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KKA02398.1 - 0.027 15.0 2.3 0.045 14.3 0.1 2.5 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KKA02398.1 - 0.051 13.7 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 KKA02398.1 - 0.063 13.4 0.4 0.6 10.2 0.1 2.5 2 1 0 2 2 2 0 Adenylate kinase AAA_28 PF13521.6 KKA02398.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KKA02398.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KKA02398.1 - 0.09 12.8 0.9 0.94 9.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKA02398.1 - 0.11 12.5 0.1 8.2 6.3 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 KKA02398.1 - 0.11 12.9 0.0 0.53 10.7 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KKA02398.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKA02398.1 - 0.21 11.9 0.0 0.47 10.8 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain AAA_23 PF13476.6 KKA02398.1 - 7 7.1 9.5 17 5.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain B-block_TFIIIC PF04182.12 KKA02399.1 - 0.14 12.3 0.4 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC NdhM PF10664.9 KKA02399.1 - 1.1 9.5 6.4 0.16 12.2 0.4 2.6 3 0 0 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M Col_cuticle_N PF01484.17 KKA02400.1 - 5.7e-05 23.1 0.2 0.097 12.7 0.2 2.5 1 1 1 2 2 2 2 Nematode cuticle collagen N-terminal domain TBCA PF02970.16 KKA02400.1 - 0.00026 21.3 10.1 0.00026 21.3 10.1 2.2 1 1 1 2 2 2 1 Tubulin binding cofactor A Laminin_II PF06009.12 KKA02400.1 - 0.00086 19.3 2.4 0.0011 19.1 1.1 1.8 1 1 0 1 1 1 1 Laminin Domain II Mononeg_mRNAcap PF14318.6 KKA02400.1 - 0.01 15.1 0.2 0.019 14.2 0.1 1.3 1 1 0 1 1 1 0 Mononegavirales mRNA-capping region V Fzo_mitofusin PF04799.13 KKA02400.1 - 0.077 12.5 4.5 0.075 12.6 1.7 2.0 1 1 1 2 2 2 0 fzo-like conserved region Rsa3 PF14615.6 KKA02400.1 - 0.15 11.7 2.1 1.8 8.2 0.2 2.4 1 1 1 2 2 2 0 Ribosome-assembly protein 3 OmpH PF03938.14 KKA02400.1 - 0.39 11.0 6.9 0.58 10.5 6.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 KKA02400.1 - 0.64 10.2 13.1 0.53 10.5 3.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 KKA02400.1 - 4.2 7.8 7.6 2.5 8.6 2.1 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Pkinase PF00069.25 KKA02402.1 - 3.8e-46 157.6 0.0 1.5e-43 149.1 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02402.1 - 5.5e-17 61.9 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKA02402.1 - 0.12 12.3 1.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family V_ATPase_I PF01496.19 KKA02403.1 - 6e-250 831.6 21.9 1.8e-183 611.7 5.9 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family GHMP_kinases_N PF00288.26 KKA02404.1 - 3e-19 69.0 0.1 5.9e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKA02404.1 - 3.4e-07 30.5 1.1 6.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KKA02404.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Mtc PF03820.17 KKA02405.1 - 9e-117 389.6 0.8 1e-116 389.4 0.8 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier GD_N PF16030.5 KKA02405.1 - 0.16 12.3 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Serine protease gd N-terminus WD40 PF00400.32 KKA02406.1 - 3.4e-21 75.2 13.4 0.00036 21.3 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KKA02406.1 - 8.8e-21 74.2 0.4 1.9e-20 73.1 0.4 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KKA02406.1 - 2.8e-07 29.6 9.9 0.00024 19.9 1.5 3.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKA02406.1 - 0.042 14.2 3.0 0.5 10.7 0.0 3.7 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKA02406.1 - 0.42 9.9 4.9 5.7 6.2 3.8 2.9 2 1 0 2 2 2 0 WD40-like domain RNA_polI_A14 PF08203.11 KKA02407.1 - 2e-11 44.4 1.9 1.2e-10 42.0 1.9 2.1 1 1 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 CAF20 PF17052.5 KKA02408.1 - 3.3e-23 82.6 6.8 2.2e-22 79.9 5.3 2.0 1 1 1 2 2 2 1 Cap associated factor Ribosomal_L18p PF00861.22 KKA02408.1 - 0.0016 18.8 0.1 0.0022 18.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Myb_DNA-binding PF00249.31 KKA02409.1 - 8.4e-23 80.3 1.2 3.1e-11 43.3 1.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA02409.1 - 1.6e-22 79.5 2.5 6.2e-12 45.6 0.5 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KKA02409.1 - 0.005 16.9 0.7 0.005 16.9 0.7 4.6 3 2 3 6 6 6 2 SLIDE Rap1_C PF11626.8 KKA02409.1 - 0.21 11.7 0.1 0.21 11.7 0.1 3.0 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain IPPT PF01715.17 KKA02412.1 - 3.7e-62 210.1 0.6 6.1e-62 209.4 0.6 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KKA02412.1 - 0.00031 20.2 0.0 0.00081 18.8 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 KKA02412.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Peptidase_S76 PF13611.6 KKA02412.1 - 0.082 13.2 0.3 0.29 11.5 0.3 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 zf-C2H2_jaz PF12171.8 KKA02412.1 - 1.7 9.1 6.1 0.26 11.6 0.8 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Tubulin_3 PF14881.6 KKA02413.1 - 3.4e-13 49.7 0.7 1.2e-12 47.9 0.2 2.1 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 KKA02413.1 - 5e-09 36.5 0.6 2.1e-08 34.5 0.6 2.1 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain MHCassoc_trimer PF08831.10 KKA02413.1 - 0.021 14.8 2.2 0.14 12.2 0.2 3.3 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DnaJ_C PF01556.18 KKA02414.1 - 5.2e-25 88.3 0.0 7.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKA02414.1 - 2.3e-18 66.1 6.1 4e-18 65.3 6.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKA02414.1 - 1.8e-09 37.8 18.6 4.1e-09 36.7 18.6 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKA02414.1 - 0.4 10.7 15.0 0.59 10.1 3.4 3.0 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Pkinase PF00069.25 KKA02415.1 - 3.2e-35 121.8 0.1 1.4e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02415.1 - 1.7e-10 40.7 1.9 6.4e-08 32.2 0.1 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase GMP_synt_C PF00958.22 KKA02416.1 - 7e-45 151.0 0.0 1.5e-44 150.0 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KKA02416.1 - 2.5e-41 141.6 0.0 4.1e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KKA02416.1 - 2.8e-09 36.4 0.1 1.1e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KKA02416.1 - 1.6e-05 24.8 0.0 0.00011 22.0 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KKA02416.1 - 0.0023 17.5 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 KKA02416.1 - 0.0032 16.8 0.2 0.0051 16.1 0.2 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 KKA02416.1 - 0.0038 16.1 0.1 0.0078 15.0 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 KKA02416.1 - 0.0082 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 KKA02416.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KKA02416.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 PP-loop family HEM4 PF02602.15 KKA02417.1 - 4.8e-40 137.3 0.0 5.5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TRAPPC10 PF12584.8 KKA02418.1 - 2.7e-09 36.9 0.0 7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 S1_2 PF13509.6 KKA02418.1 - 0.97 9.5 4.8 10 6.3 0.3 3.8 3 0 0 3 3 3 0 S1 domain RVT_1 PF00078.27 KKA02419.1 - 2.4e-31 109.0 0.2 5.1e-31 107.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KKA02419.1 - 6.9e-28 96.6 0.0 2.2e-27 95.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKA02419.1 - 6.5e-26 90.7 0.0 2.9e-25 88.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_A2B PF12384.8 KKA02419.1 - 1.4e-11 44.3 0.3 3e-11 43.2 0.3 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Integrase_H2C2 PF17921.1 KKA02419.1 - 1.6e-10 40.9 0.2 4.7e-10 39.4 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KKA02419.1 - 1.4e-09 38.2 0.1 2.8e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KKA02419.1 - 1.7e-05 25.3 0.2 5.5e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKA02419.1 - 3e-05 24.6 0.2 0.00011 22.8 0.1 2.0 2 0 0 2 2 1 1 Aspartyl protease DUF1758 PF05585.12 KKA02419.1 - 0.012 15.3 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 KKA02419.1 - 0.014 15.6 0.2 0.059 13.6 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RVP_2 PF08284.11 KKA02419.1 - 0.025 14.3 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 KKA02419.1 - 0.037 14.3 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 KKA02419.1 - 0.9 9.4 4.5 0.24 11.2 0.5 2.1 2 0 0 2 2 2 0 Integrase core domain CENP-Q PF13094.6 KKA02420.1 - 0.068 13.4 14.3 0.019 15.2 11.0 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.9 KKA02420.1 - 1.6 9.0 21.1 0.082 13.1 14.7 2.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KKA02420.1 - 2.5 7.6 10.2 3.4 7.2 10.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KKA02420.1 - 7.8 6.5 26.6 5.4 7.1 24.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Per1 PF04080.13 KKA02421.1 - 1.2e-76 257.8 15.0 1.2e-76 257.8 15.0 1.8 2 0 0 2 2 2 1 Per1-like family HCO3_cotransp PF00955.21 KKA02422.1 - 6.4e-66 223.2 18.5 7.5e-39 133.9 5.3 2.3 1 1 1 2 2 2 2 HCO3- transporter family EMG1 PF03587.14 KKA02424.1 - 5.9e-77 257.7 0.1 7.4e-77 257.4 0.1 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 KKA02424.1 - 0.047 13.4 0.2 0.073 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 Cob_adeno_trans PF01923.18 KKA02425.1 - 0.00049 20.3 0.3 0.00062 19.9 0.3 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase LCD1 PF09798.9 KKA02425.1 - 0.0014 17.3 11.2 0.0014 17.2 11.2 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein DUF641 PF04859.12 KKA02425.1 - 0.011 16.0 7.2 0.012 15.9 5.2 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) KLRAQ PF10205.9 KKA02425.1 - 0.24 11.7 8.8 0.31 11.3 8.1 1.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Ly49 PF08391.10 KKA02425.1 - 1.8 9.0 8.7 0.81 10.1 6.2 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Sec2p PF06428.11 KKA02425.1 - 2.3 8.2 11.8 0.34 10.9 3.8 2.7 2 2 0 3 3 3 0 GDP/GTP exchange factor Sec2p Myb_DNA-bind_7 PF15963.5 KKA02425.1 - 2.4 8.1 8.2 1.4 8.8 2.8 2.5 1 1 0 2 2 2 0 Myb DNA-binding like FHA PF00498.26 KKA02427.1 - 5.8e-08 33.0 0.0 1.5e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain Vta1 PF04652.16 KKA02428.1 - 1.3e-05 25.3 2.9 1.3e-05 25.3 2.9 1.8 1 1 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KKA02428.1 - 0.079 12.7 0.0 0.079 12.7 0.0 2.7 3 0 0 3 3 3 0 Vta1 C-terminal domain TFA2_Winged_2 PF18121.1 KKA02428.1 - 0.11 12.2 1.4 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 RPW8 PF05659.11 KKA02428.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.9 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Kri1 PF05178.12 KKA02428.1 - 0.65 10.6 7.7 0.16 12.5 3.7 2.1 2 0 0 2 2 2 0 KRI1-like family S-AdoMet_synt_C PF02773.16 KKA02429.1 - 1.1e-63 213.3 0.0 2.1e-63 212.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KKA02429.1 - 3.7e-46 156.3 0.0 7.6e-46 155.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KKA02429.1 - 2.6e-45 153.1 0.2 5e-45 152.2 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KKA02429.1 - 0.027 13.3 0.4 0.11 11.2 0.1 1.9 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PBP PF01161.20 KKA02430.1 - 1.8e-16 60.7 0.0 2.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 KKA02431.1 - 4e-12 46.6 0.0 4.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.25 KKA02432.1 - 4.4e-71 239.3 0.0 4.4e-71 239.3 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02432.1 - 2e-34 119.1 0.0 5e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KKA02432.1 - 1.7e-12 47.1 0.5 5.6e-12 45.4 0.5 2.0 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KKA02432.1 - 1.1e-05 25.0 0.2 5.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like HCO3_cotransp PF00955.21 KKA02432.1 - 0.15 10.9 1.6 0.5 9.1 1.6 1.9 1 0 0 1 1 1 0 HCO3- transporter family PSP1 PF04468.12 KKA02433.1 - 5.4e-32 109.9 2.2 2e-31 108.1 2.2 2.1 1 0 0 1 1 1 1 PSP1 C-terminal conserved region AA_permease PF00324.21 KKA02434.1 - 3.9e-89 299.5 46.9 4.8e-89 299.2 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02434.1 - 5.3e-14 51.9 49.1 6.8e-14 51.5 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKA02435.1 - 4.1e-94 315.9 36.7 4.7e-94 315.7 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02435.1 - 9.3e-18 64.2 37.2 1.1e-17 64.0 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKA02436.1 - 3.5e-99 332.6 38.0 4e-99 332.4 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02436.1 - 5e-14 52.0 39.4 5.9e-14 51.7 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKA02437.1 - 2.3e-103 346.3 34.7 2.9e-103 346.0 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02437.1 - 3.7e-21 75.5 36.7 4.3e-21 75.2 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KKA02437.1 - 6.2 5.5 6.6 0.44 9.3 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4781) AA_permease PF00324.21 KKA02438.1 - 2.6e-103 346.2 37.8 3.1e-103 345.9 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02438.1 - 2.8e-19 69.2 38.5 3.4e-19 69.0 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease Nitroreductase PF00881.24 KKA02439.1 - 1.4e-06 28.5 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Mhr1 PF12829.7 KKA02439.1 - 0.13 12.4 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Nitroreductase PF00881.24 KKA02440.1 - 6.4e-06 26.3 0.0 9.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Retinal PF15449.6 KKA02440.1 - 0.065 11.0 3.5 0.074 10.8 3.5 1.1 1 0 0 1 1 1 0 Retinal protein NRBF2 PF08961.10 KKA02440.1 - 0.074 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF3235 PF11574.8 KKA02440.1 - 0.91 10.4 7.1 0.98 10.3 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) CAP PF00188.26 KKA02441.1 - 1.4e-16 61.5 0.1 1.4e-16 61.5 0.1 3.7 3 1 0 3 3 3 1 Cysteine-rich secretory protein family CAP_GLY PF01302.25 KKA02442.1 - 2.5e-09 37.0 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain ATG16 PF08614.11 KKA02442.1 - 0.077 13.2 10.3 0.12 12.6 10.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 KKA02442.1 - 0.11 12.9 8.4 0.52 10.8 0.4 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1281 PF06924.11 KKA02442.1 - 0.26 10.8 1.3 0.55 9.8 1.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1281) TBCA PF02970.16 KKA02442.1 - 0.46 10.8 9.6 1 9.8 9.6 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor A DivIC PF04977.15 KKA02442.1 - 0.65 9.8 11.8 0.21 11.4 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 KKA02442.1 - 2.2 8.9 14.1 0.46 11.2 3.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 KKA02442.1 - 2.6 8.5 13.6 0.75 10.3 4.5 2.9 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins PCRF PF03462.18 KKA02442.1 - 4.6 7.0 8.0 6.6 6.6 8.0 1.2 1 0 0 1 1 1 0 PCRF domain bZIP_1 PF00170.21 KKA02442.1 - 5.9 7.1 13.2 0.43 10.7 0.3 3.3 2 1 1 3 3 3 0 bZIP transcription factor zf-C4H2 PF10146.9 KKA02442.1 - 6.9 6.9 13.0 8.9 6.6 13.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Histidinol_dh PF00815.20 KKA02443.1 - 1.8e-157 524.6 0.9 2.6e-157 524.1 0.9 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KKA02443.1 - 3.2e-24 84.6 1.1 6.9e-24 83.5 1.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KKA02443.1 - 2.1e-09 37.7 0.3 5.1e-09 36.5 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase NTP_transf_3 PF12804.7 KKA02443.1 - 0.19 12.1 0.3 0.37 11.1 0.3 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Complex1_LYR_2 PF13233.6 KKA02444.1 - 3.8e-14 53.2 1.6 1.3e-13 51.5 0.3 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKA02444.1 - 2.4e-06 27.5 0.1 5.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_Rrp7 PF17799.1 KKA02445.1 - 2.6e-50 170.4 8.3 2.6e-50 170.4 8.3 1.6 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KKA02445.1 - 1.2e-22 80.3 7.0 1.2e-22 80.3 7.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SelR PF01641.18 KKA02446.1 - 1.6e-36 125.0 0.3 7.9e-35 119.6 0.3 2.0 1 1 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KKA02446.1 - 0.036 14.3 0.9 0.066 13.4 0.9 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glutaredoxin PF00462.24 KKA02447.1 - 9.1e-14 51.4 0.2 2.8e-13 49.9 0.2 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KKA02447.1 - 0.0083 16.2 0.1 0.018 15.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin domain GST_N_2 PF13409.6 KKA02447.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 KKA02447.1 - 0.067 13.3 0.4 12 6.1 0.0 2.4 1 1 2 3 3 3 0 Thioredoxin Thioredoxin_2 PF13098.6 KKA02447.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain La PF05383.17 KKA02448.1 - 3.2e-09 36.7 0.2 7.7e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 La domain Raco_middle PF17651.1 KKA02448.1 - 0.033 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 RACo middle region ATG22 PF11700.8 KKA02449.1 - 4.5e-139 464.1 29.6 5.7e-139 463.8 29.6 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKA02449.1 - 4.8e-13 48.7 21.1 4.2e-07 29.2 15.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 KKA02450.1 - 3.2e-50 169.9 0.0 6.8e-50 168.9 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKA02450.1 - 1.1e-15 57.5 0.0 7.2e-15 54.8 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKA02450.1 - 6.9e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KKA02450.1 - 0.00072 19.2 0.0 0.0019 17.8 0.0 1.7 1 1 1 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KKA02450.1 - 0.095 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YfmQ PF10787.9 KKA02451.1 - 0.01 15.6 0.2 0.015 15.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Herpes_LMP1 PF05297.11 KKA02451.1 - 0.22 10.7 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Abhydrolase_1 PF00561.20 KKA02452.1 - 4.6e-47 160.8 0.0 7.2e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKA02452.1 - 0.00047 20.8 0.0 0.00068 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKA02452.1 - 0.0089 15.3 0.0 0.078 12.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PRIMA1 PF16101.5 KKA02452.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_76 PF03663.14 KKA02453.1 - 8.9e-114 380.8 18.6 1.2e-113 380.4 18.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 YIF1 PF03878.15 KKA02454.1 - 1.6e-61 207.9 7.3 1.6e-61 207.9 7.3 1.6 2 0 0 2 2 2 1 YIF1 Yip1 PF04893.17 KKA02454.1 - 0.054 13.2 11.2 0.25 11.0 11.4 2.0 1 1 0 1 1 1 0 Yip1 domain Glycoprot_B_PH1 PF17416.2 KKA02454.1 - 0.2 11.3 4.3 0.14 11.8 2.7 1.6 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B RtcB PF01139.17 KKA02454.1 - 0.28 10.3 1.0 0.38 9.9 1.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB CRAL_TRIO PF00650.20 KKA02455.1 - 5.1e-32 110.8 0.3 1.2e-31 109.6 0.4 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKA02455.1 - 7e-07 29.3 0.1 7e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF3211 PF11485.8 KKA02455.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) ArAE_2_N PF10337.9 KKA02456.1 - 1.4e-31 110.1 18.0 6.6e-31 107.9 11.2 3.7 2 2 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KKA02456.1 - 1.3e-11 44.7 20.3 3.7e-11 43.3 6.9 2.5 2 1 0 2 2 2 2 Fusaric acid resistance protein-like LdpA_C PF12617.8 KKA02456.1 - 0.037 13.6 0.0 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal DnaB_2 PF07261.11 KKA02456.1 - 0.13 12.0 2.6 7.4 6.4 0.0 2.9 2 0 0 2 2 2 0 Replication initiation and membrane attachment TPR_2 PF07719.17 KKA02457.1 - 2.7e-11 42.7 11.1 0.057 13.6 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKA02457.1 - 1.9e-09 37.9 3.8 1.3 9.5 0.0 6.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKA02457.1 - 3.9e-08 32.8 26.0 0.00013 21.6 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKA02457.1 - 1.2e-05 25.3 0.0 0.027 14.6 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKA02457.1 - 0.00021 21.2 12.7 8.9 6.8 0.2 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKA02457.1 - 0.00023 21.3 6.0 21 5.8 0.1 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKA02457.1 - 0.00027 20.6 2.9 1.3 8.8 0.1 4.1 4 0 0 4 4 4 2 TPR repeat TPR_20 PF14561.6 KKA02457.1 - 0.00054 20.2 0.1 6.9 7.1 0.0 5.0 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKA02457.1 - 0.00062 20.0 3.3 0.74 10.2 0.0 6.3 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKA02457.1 - 0.024 15.4 0.0 27 5.9 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA02457.1 - 0.087 13.1 12.1 4.6 7.5 0.1 5.0 3 2 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 MetOD2 PF18548.1 KKA02457.1 - 0.12 12.5 3.2 0.13 12.4 0.3 2.4 2 0 0 2 2 2 0 Metanogen output domain 2 TPR_6 PF13174.6 KKA02457.1 - 0.69 10.7 4.2 42 5.1 0.0 5.9 9 0 0 9 9 8 0 Tetratricopeptide repeat DLH PF01738.18 KKA02458.1 - 1.1e-30 106.9 0.1 1.2e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KKA02458.1 - 0.0017 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KKA02458.1 - 0.02 14.6 0.0 0.076 12.6 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold AA_permease PF00324.21 KKA02459.1 - 2.3e-117 392.6 55.4 2.8e-117 392.3 55.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA02459.1 - 8.1e-28 97.4 59.8 1.3e-27 96.7 59.8 1.3 1 1 0 1 1 1 1 Amino acid permease FH2 PF02181.23 KKA02460.1 - 3.8e-83 279.6 19.9 3.8e-83 279.6 19.9 4.1 3 1 1 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KKA02460.1 - 3.5e-35 121.4 0.8 3.5e-35 121.4 0.8 5.4 5 0 0 5 5 5 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 KKA02460.1 - 7.7e-31 107.1 11.3 7.7e-31 107.1 11.3 5.0 4 2 0 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.12 KKA02460.1 - 1.7 8.4 53.0 0.018 14.8 45.5 1.5 2 0 0 2 2 2 0 Formin Homology Region 1 Sad1_UNC PF07738.13 KKA02462.1 - 1.2e-19 70.6 0.5 2.4e-19 69.7 0.5 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Curto_V2 PF07325.11 KKA02462.1 - 0.084 12.7 2.1 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Curtovirus V2 protein DUF4201 PF13870.6 KKA02462.1 - 0.22 11.2 6.1 0.49 10.1 6.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Peptidase_S8 PF00082.22 KKA02463.1 - 6.4e-13 48.6 0.8 2e-12 47.0 0.8 1.8 1 1 0 1 1 1 1 Subtilase family Palm_thioest PF02089.15 KKA02465.1 - 6e-08 32.8 0.3 1.6e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KKA02465.1 - 6.8e-07 29.2 0.0 8.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KKA02465.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 KKA02465.1 - 3.4e-05 23.3 2.7 0.00017 21.0 0.0 2.8 3 1 1 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 KKA02465.1 - 8.4e-05 22.2 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KKA02465.1 - 0.0032 16.7 0.0 0.0067 15.6 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KKA02465.1 - 0.017 15.7 0.0 0.021 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 KKA02465.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RGS PF00615.19 KKA02466.1 - 0.46 10.8 16.5 0.46 10.8 0.5 4.6 4 1 0 4 4 4 0 Regulator of G protein signaling domain Na_H_Exchanger PF00999.21 KKA02467.1 - 1.3e-80 271.1 20.6 1.5e-80 270.8 20.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 KKA02467.1 - 9.4e-11 41.6 33.4 2e-05 24.0 22.2 2.5 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus YwiC PF14256.6 KKA02467.1 - 0.052 13.9 0.2 0.052 13.9 0.2 2.5 2 0 0 2 2 2 0 YwiC-like protein ThiW PF09512.10 KKA02467.1 - 0.21 11.7 3.9 2.2 8.4 0.0 3.2 3 0 0 3 3 3 0 Thiamine-precursor transporter protein (ThiW) DUF4190 PF13828.6 KKA02467.1 - 1 9.2 4.1 7.9 6.3 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) PIEZO PF15917.5 KKA02467.1 - 1.9 7.9 6.6 4.9 6.6 6.6 1.8 1 0 0 1 1 1 0 Piezo zf-CCHC PF00098.23 KKA02468.1 - 1.7e-46 154.3 46.6 6.2e-08 32.4 1.8 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 KKA02468.1 - 4.5e-11 42.3 35.2 0.033 13.9 1.0 6.1 5 1 1 6 6 6 6 Zinc knuckle zf-CCHC_6 PF15288.6 KKA02468.1 - 0.00099 18.9 2.3 0.00099 18.9 2.3 6.1 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.6 KKA02468.1 - 0.0036 17.2 53.3 0.023 14.7 2.0 6.0 2 2 4 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KKA02468.1 - 0.0098 15.6 35.0 0.18 11.5 0.5 6.0 5 1 1 6 6 6 4 GAG-polyprotein viral zinc-finger DZR PF12773.7 KKA02468.1 - 5.7 7.1 40.1 13 5.9 4.9 4.5 1 1 1 2 2 2 0 Double zinc ribbon MRP-L46 PF11788.8 KKA02469.1 - 2.1e-18 67.2 2.1 2.1e-18 67.2 2.1 2.0 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 DnaJ PF00226.31 KKA02470.1 - 3e-13 49.7 0.9 5.3e-13 48.9 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KKA02470.1 - 8.6e-11 41.4 2.7 1.5e-10 40.6 2.7 1.4 1 0 0 1 1 1 1 CSL zinc finger tRNA-synt_1e PF01406.19 KKA02471.1 - 1e-135 451.9 1.0 1e-135 451.9 1.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KKA02471.1 - 4.4e-08 32.3 5.8 5.5e-06 25.4 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKA02471.1 - 0.00015 20.2 3.2 0.001 17.4 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 KKA02471.1 - 0.012 14.5 0.0 0.012 14.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain NAP PF00956.18 KKA02472.1 - 2.6e-11 43.2 12.1 1.2e-10 41.0 11.6 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Nas2_N PF18265.1 KKA02472.1 - 0.056 13.4 0.2 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Nas2 N_terminal domain ANTH PF07651.16 KKA02473.1 - 6.3e-58 195.9 0.0 6.3e-58 195.9 0.0 3.4 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KKA02473.1 - 2.1e-48 164.4 4.8 2.1e-48 164.4 4.8 5.0 3 1 2 5 5 5 1 I/LWEQ domain ENTH PF01417.20 KKA02473.1 - 0.0001 22.3 3.4 0.00019 21.4 0.0 3.3 3 0 0 3 3 3 1 ENTH domain Activator_LAG-3 PF11498.8 KKA02473.1 - 0.0018 17.4 36.7 0.0018 17.4 36.7 2.4 2 1 0 2 2 2 1 Transcriptional activator LAG-3 Spc7 PF08317.11 KKA02473.1 - 0.0044 15.9 21.0 0.0044 15.9 21.0 4.9 3 1 2 5 5 5 1 Spc7 kinetochore protein Rubrerythrin PF02915.17 KKA02473.1 - 0.0058 17.0 4.6 0.0058 17.0 4.6 3.6 3 0 0 3 3 3 1 Rubrerythrin SDH_beta PF03315.15 KKA02473.1 - 0.96 9.8 3.1 46 4.4 0.8 3.3 2 0 0 2 2 2 0 Serine dehydratase beta chain TFCD_C PF12612.8 KKA02476.1 - 2.8 7.7 7.1 13 5.6 0.6 3.4 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal FCH PF00611.23 KKA02476.1 - 3.8 7.8 5.6 4.5 7.6 3.6 2.3 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain RasGEF PF00617.19 KKA02477.1 - 7.3e-33 114.2 3.6 7.3e-33 114.2 3.6 3.2 3 1 1 4 4 4 1 RasGEF domain RasGEF_N PF00618.20 KKA02477.1 - 1e-10 41.8 2.2 1e-10 41.8 2.2 3.8 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 KKA02477.1 - 0.041 13.5 0.2 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 SH3 domain PI_PP_I PF18363.1 KKA02477.1 - 0.098 12.8 3.9 0.19 12.0 0.7 3.2 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Surp PF01805.20 KKA02479.1 - 0.0049 16.8 0.2 0.0049 16.8 0.2 2.5 3 0 0 3 3 3 1 Surp module Sec10 PF07393.11 KKA02480.1 - 1.7e-33 116.1 19.8 3.8e-33 114.9 19.8 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec10 RNase_H2_suC PF08615.11 KKA02481.1 - 0.0018 18.5 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SPX PF03105.19 KKA02482.1 - 1.4e-50 173.4 27.0 1.8e-50 173.0 27.0 1.1 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.19 KKA02482.1 - 1.8e-26 93.2 40.7 4.8e-26 91.8 40.7 2.0 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KKA02482.1 - 1.4e-25 90.2 51.5 1.1e-21 77.4 26.7 2.2 1 1 1 2 2 2 2 Citrate transporter DctM PF06808.12 KKA02482.1 - 0.0033 16.3 39.5 0.0046 15.8 15.0 2.5 2 1 1 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component Med13_C PF06333.12 KKA02482.1 - 0.29 10.4 0.9 0.54 9.5 0.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain APAF1_C PF17908.1 KKA02482.1 - 0.36 10.8 3.4 0.41 10.6 0.0 2.6 3 0 0 3 3 3 0 APAF-1 helical domain DUF3545 PF12065.8 KKA02482.1 - 8.3 6.5 8.2 6.1 7.0 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3545) UCH PF00443.29 KKA02483.1 - 5.7e-74 248.9 2.2 9e-74 248.2 2.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKA02483.1 - 2.4e-16 60.2 0.6 1.7e-08 34.4 0.5 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF1935 PF09149.10 KKA02483.1 - 0.096 13.1 0.2 0.78 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) PriX PF18689.1 KKA02483.1 - 0.33 11.3 2.4 0.48 10.8 0.2 2.4 2 0 0 2 2 2 0 Primase X RNase_PH PF01138.21 KKA02484.1 - 0.0059 17.1 0.0 0.018 15.5 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF465 PF04325.13 KKA02484.1 - 0.31 11.1 3.9 2.8 8.0 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) AAA_22 PF13401.6 KKA02485.1 - 2.8e-06 27.6 0.0 7.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKA02485.1 - 1.7e-05 25.2 0.0 0.00019 21.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KKA02485.1 - 7.1e-05 23.2 0.0 0.00053 20.4 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KKA02485.1 - 0.032 14.0 0.0 0.032 14.0 0.0 3.1 3 2 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 KKA02485.1 - 0.032 14.3 0.2 28 4.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.14 KKA02485.1 - 0.056 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKA02485.1 - 0.057 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPT PF03151.16 KKA02486.1 - 3.4e-29 102.1 21.9 2.2e-15 56.8 3.0 3.3 3 1 0 3 3 3 3 Triose-phosphate Transporter family Ribosomal_S8 PF00410.19 KKA02487.1 - 2.3e-24 85.8 0.1 3.3e-24 85.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Brr6_like_C_C PF10104.9 KKA02488.1 - 4.9e-11 42.5 2.4 1.4e-09 37.8 0.3 2.1 2 0 0 2 2 2 2 Di-sulfide bridge nucleocytoplasmic transport domain Glycophorin_A PF01102.18 KKA02488.1 - 0.021 15.1 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A muHD PF10291.9 KKA02489.1 - 2.8e-29 102.4 0.8 2.8e-29 102.4 0.8 2.1 3 0 0 3 3 3 1 Muniscin C-terminal mu homology domain MA3 PF02847.17 KKA02489.1 - 0.32 11.0 2.5 1.8 8.6 0.3 2.5 1 1 1 2 2 2 0 MA3 domain AICARFT_IMPCHas PF01808.18 KKA02490.1 - 1.1e-91 307.3 0.0 1.6e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KKA02490.1 - 3.9e-25 87.9 0.1 1e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain Dis3l2_C_term PF17877.1 KKA02490.1 - 0.016 15.5 0.0 0.065 13.6 0.0 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal Ribosomal_L15e PF00827.17 KKA02491.1 - 6e-88 293.6 11.9 7.5e-88 293.3 11.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Homeobox_KN PF05920.11 KKA02492.1 - 4.5e-19 68.1 0.2 1.2e-18 66.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KKA02492.1 - 1.7e-06 27.7 2.1 1.9e-06 27.6 0.2 2.1 2 0 0 2 2 2 1 Homeodomain DUF3492 PF11997.8 KKA02492.1 - 0.095 12.4 0.4 0.13 12.0 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) Metallophos PF00149.28 KKA02493.1 - 1.3e-38 133.5 0.0 2.9e-38 132.4 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKA02493.1 - 7.3e-15 55.1 0.8 1.5e-14 54.2 0.3 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PHD PF00628.29 KKA02494.1 - 1.4e-08 34.5 7.6 2.6e-08 33.6 7.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKA02494.1 - 0.023 14.3 5.3 0.041 13.5 5.3 1.4 1 0 0 1 1 1 0 PHD-finger DUF2937 PF11157.8 KKA02494.1 - 0.25 11.1 1.3 16 5.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) MF_alpha_N PF05436.11 KKA02495.1 - 6.1e-22 77.3 0.3 8.4e-22 76.9 0.3 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Apidaecin PF00807.17 KKA02495.1 - 1.2 9.2 13.6 6.9 6.9 0.9 3.3 3 0 0 3 3 3 0 Apidaecin PAGK PF15284.6 KKA02495.1 - 1.5 8.8 4.2 20 5.2 0.3 2.3 1 1 1 2 2 2 0 Phage-encoded virulence factor Ribosomal_S17 PF00366.20 KKA02496.1 - 3e-11 43.2 0.7 6.9e-11 42.1 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 Vac14_Fig4_bd PF11916.8 KKA02496.1 - 0.005 16.5 1.6 0.01 15.5 1.6 1.6 1 1 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding IZUMO PF15005.6 KKA02496.1 - 2.6 8.6 13.2 0.43 11.1 6.3 2.3 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CN_hydrolase PF00795.22 KKA02497.1 - 7.8e-36 123.7 0.0 9.1e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4889 PF16230.5 KKA02497.1 - 0.0089 16.2 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4889) Lectin_leg-like PF03388.13 KKA02499.1 - 3.9e-11 42.7 0.6 5.9e-11 42.2 0.6 1.2 1 0 0 1 1 1 1 Legume-like lectin family LigB PF02900.18 KKA02500.1 - 5.6e-16 58.4 0.0 1.1e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Tantalus PF15386.6 KKA02500.1 - 0.035 14.2 0.4 0.081 13.0 0.4 1.6 1 0 0 1 1 1 0 Drosophila Tantalus-like CybS PF05328.12 KKA02502.1 - 4.4e-42 142.9 0.0 5.5e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit IL6 PF00489.17 KKA02502.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family zf-C3H2C3 PF17122.5 KKA02503.1 - 7.6e-06 25.9 5.4 1.4e-05 25.1 5.4 1.4 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 KKA02503.1 - 0.0011 18.9 2.5 0.002 18.1 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KKA02503.1 - 0.0099 15.5 1.3 0.017 14.7 1.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type AbiJ_NTD3 PF18860.1 KKA02503.1 - 0.011 15.3 3.2 1.5 8.3 0.3 2.9 1 1 1 2 2 2 0 AbiJ N-terminal domain 3 zf-RING_2 PF13639.6 KKA02503.1 - 0.028 14.7 4.5 0.052 13.9 4.5 1.4 1 0 0 1 1 1 0 Ring finger domain MIT PF04212.18 KKA02503.1 - 0.042 13.9 0.1 0.19 11.8 0.1 2.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-ribbon_3 PF13248.6 KKA02503.1 - 0.074 12.5 1.2 0.17 11.4 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KKA02503.1 - 0.13 12.1 6.1 0.25 11.2 6.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.6 KKA02503.1 - 0.14 12.4 2.5 0.27 11.6 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KKA02503.1 - 0.28 11.2 3.1 0.72 9.9 3.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 KKA02503.1 - 0.45 10.7 2.7 0.76 9.9 0.7 2.2 2 0 0 2 2 2 0 Zinc ribbon domain DUF1272 PF06906.11 KKA02503.1 - 1.1 9.5 2.9 2.6 8.2 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) RRS1 PF04939.12 KKA02505.1 - 4e-55 186.1 6.5 4.7e-55 185.9 6.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RNase_H PF00075.24 KKA02507.1 - 3.8e-14 53.1 0.3 1.6e-13 51.1 0.0 2.3 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 KKA02507.1 - 9.1e-14 51.5 0.3 2.9e-13 49.9 0.3 2.0 1 0 0 1 1 1 1 Caulimovirus viroplasmin Lyase_1 PF00206.20 KKA02508.1 - 5.3e-24 85.2 0.0 9.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KKA02508.1 - 7.5e-16 58.5 0.0 5.3e-15 55.7 0.0 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Amidohydro_1 PF01979.20 KKA02508.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family DUF1331 PF07048.11 KKA02508.1 - 0.44 10.2 1.6 0.41 10.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) YgaB PF14182.6 KKA02508.1 - 0.52 10.7 2.5 17 5.9 0.1 3.1 3 0 0 3 3 3 0 YgaB-like protein BCNT PF07572.12 KKA02509.1 - 2.8e-13 49.7 1.3 2.8e-13 49.7 1.3 2.2 2 0 0 2 2 2 1 Bucentaur or craniofacial development USP7_ICP0_bdg PF12436.8 KKA02510.1 - 0.00061 19.2 1.9 0.0012 18.2 1.9 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 EDR1 PF14381.6 KKA02511.1 - 0.083 12.6 4.6 0.16 11.6 4.6 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 RAMPs PF03787.15 KKA02511.1 - 0.69 9.9 9.6 0.3 11.1 6.4 2.1 1 1 1 2 2 2 0 RAMP superfamily Cation_ATPase_C PF00689.21 KKA02512.1 - 4.5e-39 134.0 12.6 4.5e-39 134.0 12.6 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKA02512.1 - 1.5e-34 119.1 0.0 1.5e-34 119.1 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKA02512.1 - 3.2e-14 52.8 0.4 8.9e-14 51.3 0.4 1.9 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKA02512.1 - 1.5e-11 45.0 1.1 2.7e-10 40.9 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKA02512.1 - 1.1e-10 41.0 0.0 3.2e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKA02512.1 - 2.1e-05 24.4 4.3 3.6e-05 23.6 0.3 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 KKA02512.1 - 0.26 10.0 4.5 1.1 7.9 2.5 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.8 KKA02512.1 - 2.4 8.3 5.2 1.8 8.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function Pox_MCEL PF03291.16 KKA02513.1 - 4.9e-90 302.0 0.5 4.9e-90 302.0 0.5 1.9 1 1 2 3 3 3 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KKA02513.1 - 4.3e-08 33.7 0.0 1.7e-07 31.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA02513.1 - 1.8e-07 31.8 1.2 1.7e-06 28.7 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKA02513.1 - 0.00022 21.1 2.5 0.00064 19.6 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA02513.1 - 0.0011 19.5 0.0 0.0067 17.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKA02513.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Thioesterase PF00975.20 KKA02513.1 - 0.11 12.6 0.9 0.16 12.0 0.9 1.2 1 0 0 1 1 1 0 Thioesterase domain LMBR1 PF04791.16 KKA02513.1 - 4 6.2 11.6 5.7 5.7 11.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ARA70 PF12489.8 KKA02513.1 - 9.7 6.4 13.2 16 5.7 3.6 2.3 1 1 1 2 2 2 0 Nuclear coactivator ANAPC4_WD40 PF12894.7 KKA02514.1 - 0.0011 19.2 0.2 0.94 9.8 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 KKA02514.1 - 0.026 13.8 0.1 7.3 5.8 0.1 3.2 2 1 0 2 2 2 0 CPSF A subunit region YpM PF09144.10 KKA02514.1 - 0.071 13.3 2.4 5.3 7.2 0.1 3.2 2 1 1 3 3 3 0 Yersinia pseudo-tuberculosis mitogen WD40 PF00400.32 KKA02514.1 - 0.75 10.8 6.6 2.9 8.9 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat RRM_1 PF00076.22 KKA02515.1 - 9.2e-11 41.4 0.7 4.1e-06 26.5 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KKA02515.1 - 0.056 13.1 0.4 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 KKA02515.1 - 0.064 13.3 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DUF1866 PF08952.11 KKA02515.1 - 0.11 12.3 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) ParA PF10609.9 KKA02517.1 - 2.7e-85 285.8 0.0 3.4e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKA02517.1 - 3.4e-08 33.6 0.0 9.8e-08 32.1 0.0 1.8 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKA02517.1 - 3.8e-08 33.5 0.9 7.6e-08 32.5 0.9 1.5 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KKA02517.1 - 0.00013 21.3 1.2 0.0027 16.9 0.0 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 KKA02517.1 - 0.00031 20.6 0.0 0.0094 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKA02517.1 - 0.0007 19.5 0.3 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase MipZ PF09140.11 KKA02517.1 - 0.0059 15.9 0.0 0.021 14.1 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_15 PF13175.6 KKA02517.1 - 0.013 15.2 4.3 0.017 14.8 4.3 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KKA02517.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KKA02517.1 - 0.025 14.4 0.4 0.12 12.2 0.4 2.0 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 KKA02517.1 - 0.08 12.5 0.0 0.25 10.9 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KKA02517.1 - 0.086 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 KKA02517.1 - 0.26 10.9 0.0 0.57 9.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNase_T PF00929.24 KKA02518.1 - 2.5e-13 50.9 0.0 8.1e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Exonuclease SNase PF00565.17 KKA02519.1 - 2.9e-25 88.8 0.0 9.8e-25 87.1 0.0 1.9 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.25 KKA02520.1 - 3.6e-14 52.8 0.8 3.6e-14 52.8 0.8 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02520.1 - 3.1e-06 26.7 0.1 3.1e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase ExsD PF16806.5 KKA02520.1 - 0.032 14.2 5.2 1.3 8.9 0.6 2.7 1 1 1 2 2 2 0 Antiactivator protein ExsD DCB PF16213.5 KKA02520.1 - 0.23 11.1 6.1 0.13 12.0 3.0 2.0 1 1 1 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 RRM_1 PF00076.22 KKA02521.1 - 3.5e-09 36.3 2.3 3.9e-08 33.0 0.4 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKA02521.1 - 3.5e-05 23.4 0.0 3.5e-05 23.4 0.0 3.1 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 KKA02522.1 - 4.3e-47 160.9 47.4 5.4e-47 160.6 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKA02522.1 - 1.9e-27 96.0 40.0 2.3e-27 95.7 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease TLD PF07534.16 KKA02523.1 - 1.8e-26 93.1 1.3 3e-26 92.3 1.3 1.4 1 0 0 1 1 1 1 TLD Adaptin_N PF01602.20 KKA02524.1 - 6.1e-93 312.1 10.7 1.1e-92 311.3 10.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKA02524.1 - 3.5e-11 43.4 4.6 1.9e-07 31.2 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKA02524.1 - 1.4e-05 24.9 0.1 1.6 9.2 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat Cnd3 PF12719.7 KKA02524.1 - 0.00022 20.5 0.7 0.025 13.8 0.0 3.2 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KKA02524.1 - 0.00072 19.9 0.0 0.15 12.5 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KKA02524.1 - 0.072 13.7 1.9 7.8 7.2 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 KKA02524.1 - 0.12 12.5 0.0 9.8 6.4 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Rad9 PF04139.13 KKA02525.1 - 1.5e-05 24.6 2.9 0.0022 17.5 0.0 3.2 2 1 0 2 2 2 2 Rad9 RNA_pol_A_CTD PF03118.15 KKA02525.1 - 0.0005 19.8 0.5 0.0059 16.4 0.0 3.0 3 0 0 3 3 3 1 Bacterial RNA polymerase, alpha chain C terminal domain DPM3 PF08285.11 KKA02525.1 - 0.044 14.0 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Peptidase_M20 PF01546.28 KKA02526.1 - 4.2e-28 98.5 0.3 3e-27 95.7 0.3 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKA02526.1 - 0.00031 20.6 0.0 0.00077 19.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain ABC_tran PF00005.27 KKA02527.1 - 3.9e-16 59.8 0.1 9e-16 58.6 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKA02527.1 - 6.1e-08 32.8 11.1 0.00012 22.1 3.7 2.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKA02527.1 - 2.1e-05 25.1 0.1 2.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KKA02527.1 - 3e-05 23.6 0.2 0.083 12.3 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KKA02527.1 - 7.9e-05 22.5 2.1 0.0011 18.7 0.7 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KKA02527.1 - 0.0017 18.0 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KKA02527.1 - 0.0019 16.9 0.1 0.0023 16.7 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKA02527.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KKA02527.1 - 0.098 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KKA02527.1 - 0.15 11.8 0.2 0.34 10.6 0.2 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KKA02527.1 - 0.38 10.3 1.2 0.71 9.4 1.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Med4 PF10018.9 KKA02528.1 - 2.7e-08 33.8 9.2 4.9e-08 32.9 9.2 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TFIIA PF03153.13 KKA02528.1 - 0.021 14.8 10.9 0.028 14.4 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IF-2B PF01008.17 KKA02529.1 - 8.2e-46 156.5 1.2 3.2e-45 154.5 1.2 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family RE_SinI PF09570.10 KKA02529.1 - 0.011 15.0 0.2 0.082 12.1 0.0 2.2 2 0 0 2 2 2 0 SinI restriction endonuclease ThiG PF05690.14 KKA02529.1 - 0.069 12.5 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Hph PF13694.6 KKA02529.1 - 3.3 8.0 6.4 0.34 11.2 0.6 2.2 3 0 0 3 3 3 0 Sec63/Sec62 complex-interacting family WH1 PF00568.23 KKA02530.1 - 4.4e-30 103.9 0.1 9.7e-30 102.8 0.0 1.5 2 0 0 2 2 2 1 WH1 domain GCIP PF13324.6 KKA02531.1 - 3.4e-07 30.2 12.0 1.9e-05 24.4 8.7 2.2 2 0 0 2 2 2 2 Grap2 and cyclin-D-interacting Aminotran_5 PF00266.19 KKA02532.1 - 2.7e-28 99.0 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MIT_C PF16565.5 KKA02532.1 - 0.066 13.2 0.1 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT UB2H PF14814.6 KKA02533.1 - 0.11 12.5 0.3 0.54 10.3 0.2 2.1 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain Tyosinase_C PF18132.1 KKA02534.1 - 0.014 16.0 0.1 0.23 12.2 0.0 2.2 2 0 0 2 2 2 0 Tyosinase C-terminal domain YL1 PF05764.13 KKA02535.1 - 0.0038 17.4 9.4 0.0062 16.7 9.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein LAT PF15234.6 KKA02535.1 - 0.0092 15.7 3.3 0.02 14.6 3.3 1.7 1 0 0 1 1 1 1 Linker for activation of T-cells RNA_pol_3_Rpc31 PF11705.8 KKA02535.1 - 0.34 11.1 12.8 0.039 14.2 6.4 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KKA02535.1 - 0.36 10.1 8.2 0.54 9.5 8.2 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KKA02535.1 - 3.3 8.2 14.0 7.7 7.0 14.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KKA02535.1 - 5.2 7.5 9.5 4.4 7.8 7.4 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldedh PF00171.22 KKA02536.1 - 3.4e-16 58.8 0.1 3.6e-11 42.2 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LDB19 PF13002.7 KKA02537.1 - 2.9e-46 157.6 0.2 5.6e-46 156.7 0.2 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KKA02537.1 - 0.019 15.0 0.0 0.063 13.3 0.0 1.9 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKA02537.1 - 0.033 14.6 11.2 0.066 13.7 5.1 3.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF4606 PF15379.6 KKA02537.1 - 0.059 13.6 0.0 0.059 13.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4606) SNF2_N PF00176.23 KKA02538.1 - 1.3e-54 185.3 0.2 2.4e-54 184.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA02538.1 - 4.9e-21 75.2 0.8 1.3e-17 64.2 0.1 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02538.1 - 7.7e-10 39.0 0.0 7.2e-09 35.9 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKA02538.1 - 5.2e-06 25.8 0.2 1.4e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 KKA02538.1 - 0.042 13.6 0.0 3.9 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Gal11_ABD1 PF18535.1 KKA02539.1 - 3.7e-14 52.6 0.2 3.7e-14 52.6 0.2 4.5 6 0 0 6 6 6 1 Gal11 activator-binding domain (ABD1) KIX_2 PF16987.5 KKA02539.1 - 4.2e-10 39.5 1.4 4.2e-10 39.5 1.4 3.7 5 0 0 5 5 5 1 KIX domain GSH_synth_ATP PF03917.17 KKA02540.1 - 4.6e-118 394.2 2.5 5.3e-118 394.1 2.5 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KKA02540.1 - 5.1e-32 110.4 0.8 2.1e-31 108.4 0.5 2.3 2 0 0 2 2 2 1 Eukaryotic glutathione synthase DUF5063 PF16702.5 KKA02540.1 - 0.075 13.4 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) Cor1 PF04803.12 KKA02541.1 - 0.0056 16.9 0.3 0.0056 16.9 0.3 2.2 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region AChE_tetra PF08674.10 KKA02541.1 - 0.066 12.9 0.3 0.19 11.4 0.2 1.9 1 1 0 1 1 1 0 Acetylcholinesterase tetramerisation domain AAA PF00004.29 KKA02541.1 - 0.14 12.5 1.3 0.32 11.4 1.2 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HEAT PF02985.22 KKA02542.1 - 7.9e-32 106.6 7.2 0.0075 16.4 0.2 11.8 12 0 0 12 12 12 8 HEAT repeat HEAT_2 PF13646.6 KKA02542.1 - 8.5e-21 74.2 0.0 0.00023 21.5 0.0 8.6 4 3 3 8 8 8 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KKA02542.1 - 2.3e-12 47.4 12.3 0.0048 17.5 0.0 8.0 6 3 3 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KKA02542.1 - 2.5e-07 31.1 0.0 30 5.3 0.0 7.4 7 0 0 7 7 7 0 HEAT-like repeat Cnd1 PF12717.7 KKA02542.1 - 2e-06 28.0 17.2 0.0039 17.2 0.1 5.6 4 2 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKA02542.1 - 0.00013 21.6 6.7 0.06 12.9 1.4 4.1 4 1 0 4 4 4 2 CLASP N terminal Swi6_N PF18530.1 KKA02542.1 - 0.0029 17.7 0.3 0.42 10.8 0.0 3.9 3 0 0 3 3 3 1 Swi6 N-terminal domain API5 PF05918.11 KKA02542.1 - 0.013 14.3 5.3 2.9 6.6 0.0 4.2 4 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) IFRD PF05004.13 KKA02542.1 - 0.027 13.6 1.8 0.66 9.0 0.1 3.6 4 2 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Phage_int_SAM_5 PF13102.6 KKA02543.1 - 0.072 13.4 4.7 0.19 12.1 4.7 1.8 1 0 0 1 1 1 0 Phage integrase SAM-like domain FAD_SOX PF18371.1 KKA02543.1 - 0.86 10.0 10.0 1.7 9.1 1.2 2.8 2 1 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Ribosomal_60s PF00428.19 KKA02544.1 - 4.8e-22 78.4 14.4 5.7e-22 78.1 14.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TetR_C_31 PF17940.1 KKA02544.1 - 0.0054 16.9 1.2 0.0072 16.5 0.7 1.6 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain ANAPC15 PF15243.6 KKA02544.1 - 0.06 13.8 0.1 0.076 13.4 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Cys_Met_Meta_PP PF01053.20 KKA02545.1 - 5.1e-145 482.8 0.0 5.7e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KKA02545.1 - 2e-05 23.3 0.0 2.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 KKA02545.1 - 0.00031 20.0 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKA02545.1 - 0.0033 16.4 0.1 0.0074 15.3 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V SIL1 PF16782.5 KKA02546.1 - 2.7e-51 174.5 21.0 3.6e-51 174.1 21.0 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF5395 PF17373.2 KKA02546.1 - 0.048 14.3 0.3 0.52 11.0 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5395) Helicase_PWI PF18149.1 KKA02546.1 - 1.3 9.2 12.1 0.068 13.3 1.8 2.9 3 1 1 4 4 4 0 N-terminal helicase PWI domain RasGEF_N_2 PF14663.6 KKA02546.1 - 2.3 8.7 8.5 19 5.7 2.0 3.0 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Spo7 PF03907.13 KKA02547.1 - 1.1e-22 80.7 12.4 1.7e-22 80.0 12.4 1.3 1 0 0 1 1 1 1 Spo7-like protein FUN14 PF04930.15 KKA02549.1 - 0.11 12.9 1.3 0.21 12.0 1.3 1.4 1 0 0 1 1 1 0 FUN14 family zf_CCCH_4 PF18345.1 KKA02550.1 - 2e-05 24.5 27.6 0.00017 21.5 1.7 4.9 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 KKA02550.1 - 3.5e-05 23.6 34.3 0.024 14.5 0.6 5.1 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KKA02550.1 - 0.00017 22.3 1.1 0.00017 22.3 1.1 3.6 3 1 1 4 4 4 2 Torus domain PABP PF00658.18 KKA02550.1 - 0.23 11.7 1.8 17 5.7 0.0 2.9 2 1 0 2 2 2 0 Poly-adenylate binding protein, unique domain Tautomerase PF01361.21 KKA02550.1 - 0.4 10.6 1.4 2.3 8.2 0.2 2.3 2 0 0 2 2 2 0 Tautomerase enzyme Pil1 PF13805.6 KKA02551.1 - 1.4e-120 401.8 0.5 1.6e-120 401.5 0.5 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 Nop10p PF04135.12 KKA02551.1 - 0.078 13.0 2.8 2.3 8.3 0.4 2.3 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DRY_EERY PF09750.9 KKA02551.1 - 0.16 12.2 2.7 0.36 11.1 2.7 1.6 1 0 0 1 1 1 0 Alternative splicing regulator DEK_C PF08766.11 KKA02551.1 - 0.32 11.0 0.1 0.32 11.0 0.1 2.4 2 1 0 2 2 2 0 DEK C terminal domain COG4 PF08318.12 KKA02552.1 - 1.7e-21 76.7 5.7 1.1e-13 51.0 0.2 3.2 4 0 0 4 4 4 2 COG4 transport protein Ribosomal_L5_C PF00673.21 KKA02553.1 - 3.8e-22 78.3 0.0 6.1e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKA02553.1 - 8.7e-20 70.8 0.1 2e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 IF-2B PF01008.17 KKA02554.1 - 2.1e-77 260.1 0.0 2.1e-77 260.1 0.0 2.5 2 1 0 2 2 2 1 Initiation factor 2 subunit family TANGO2 PF05742.12 KKA02554.1 - 0.26 11.3 9.2 0.11 12.5 5.8 2.1 2 0 0 2 2 2 0 Transport and Golgi organisation 2 Bul1_N PF04425.12 KKA02555.1 - 4.3e-73 246.6 8.2 1e-70 238.8 5.0 4.3 2 1 3 5 5 5 2 Bul1 N terminus Bul1_C PF04426.12 KKA02555.1 - 6.5e-24 84.8 11.9 1e-12 48.0 0.1 3.7 3 2 2 5 5 5 2 Bul1 C terminus Bul1_N PF04425.12 KKA02556.1 - 1e-75 255.3 8.5 1e-75 255.3 8.5 2.8 2 1 0 2 2 2 1 Bul1 N terminus DUF2719 PF10891.8 KKA02556.1 - 0.075 12.9 0.3 0.2 11.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Cyt-b5 PF00173.28 KKA02557.1 - 2.2e-15 56.5 0.1 4.9e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KKA02557.1 - 7.1e-14 52.3 13.6 7.1e-14 52.3 13.6 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 KKA02557.1 - 0.00018 21.3 0.2 0.031 14.1 0.0 2.6 2 0 0 2 2 2 2 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.13 KKA02557.1 - 0.048 13.9 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Pribosyltran PF00156.27 KKA02558.1 - 8.1e-16 57.9 0.1 1.2e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-HC2 PF13490.6 KKA02558.1 - 0.021 15.0 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative zinc-finger Las1 PF04031.13 KKA02559.1 - 6.8e-21 75.0 0.0 1.3e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Las1-like RRM_1 PF00076.22 KKA02560.1 - 3e-28 97.4 2.4 1.8e-15 56.5 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKA02560.1 - 0.038 14.0 1.6 0.82 9.7 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 KKA02560.1 - 0.051 13.4 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Auts2 PF15336.6 KKA02560.1 - 0.2 11.8 2.2 0.45 10.6 2.0 1.7 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein RNA_polI_A34 PF08208.11 KKA02561.1 - 1.5e-07 31.7 35.9 5e-07 30.0 34.0 2.3 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Tim17 PF02466.19 KKA02563.1 - 4.2e-30 104.4 7.4 5.3e-30 104.1 7.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LCIB_C_CA PF18599.1 KKA02563.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Fe_hyd_lg_C PF02906.14 KKA02564.1 - 6.1e-43 147.2 0.1 1.3e-42 146.2 0.1 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain G6PD_C PF02781.16 KKA02565.1 - 2.5e-108 361.7 0.0 3.9e-108 361.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KKA02565.1 - 1.3e-57 195.2 0.1 2.4e-57 194.4 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med16 PF11635.8 KKA02567.1 - 9.8e-65 218.9 28.3 1.3e-64 218.4 28.3 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 PDZ_5 PF17817.1 KKA02568.1 - 0.00061 20.0 0.8 0.035 14.4 0.0 3.4 2 0 0 2 2 2 1 PDZ domain EXOSC1 PF10447.9 KKA02569.1 - 7.8e-25 87.6 1.1 1.7e-24 86.6 0.3 1.8 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 DnaJ PF00226.31 KKA02571.1 - 3.6e-23 81.4 2.1 1.5e-22 79.5 2.1 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KKA02571.1 - 2.1e-08 34.2 5.8 2.1e-08 34.2 5.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKA02571.1 - 6.9e-06 26.3 6.2 2.4e-05 24.5 2.7 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKA02571.1 - 0.023 15.5 9.3 0.25 12.3 0.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKA02571.1 - 0.045 14.2 8.1 0.074 13.5 0.9 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA02571.1 - 0.13 12.7 3.3 0.2 12.2 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 KKA02571.1 - 0.26 11.6 12.7 0.33 11.3 1.5 3.5 4 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KKA02571.1 - 5 7.2 6.4 20 5.3 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger ERM PF00769.19 KKA02572.1 - 0.00077 19.4 7.7 0.00077 19.4 7.7 2.4 3 0 0 3 3 3 1 Ezrin/radixin/moesin family CREPT PF16566.5 KKA02572.1 - 0.0028 17.8 2.9 0.0028 17.8 2.9 3.1 2 1 1 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour DUF4164 PF13747.6 KKA02572.1 - 0.0029 17.8 0.8 0.0029 17.8 0.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) ZapB PF06005.12 KKA02572.1 - 0.0071 16.8 6.4 0.0071 16.8 6.4 3.5 1 1 1 2 2 2 1 Cell division protein ZapB DivIC PF04977.15 KKA02572.1 - 0.027 14.3 1.1 0.18 11.6 1.1 2.5 1 0 0 1 1 1 0 Septum formation initiator KH_10 PF17905.1 KKA02572.1 - 0.068 13.6 1.0 0.29 11.6 1.0 2.1 1 0 0 1 1 1 0 GLD-3 KH domain 5 HIP1_clath_bdg PF16515.5 KKA02572.1 - 0.13 12.9 11.1 0.35 11.5 3.0 3.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KKA02572.1 - 0.61 10.1 11.4 4.2 7.4 5.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KKA02572.1 - 3.4 6.9 12.6 0.46 9.7 2.8 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3450) PTPS PF01242.19 KKA02572.1 - 6.2 6.8 6.6 0.79 9.7 0.1 2.7 3 1 1 4 4 4 0 6-pyruvoyl tetrahydropterin synthase DUF948 PF06103.11 KKA02572.1 - 9 6.6 10.7 19 5.6 2.4 4.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Peptidase_C54 PF03416.19 KKA02573.1 - 7e-59 199.5 0.1 8.1e-59 199.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 KKA02574.1 - 1.1e-44 152.2 0.1 1.3e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein zf-C3HC4_5 PF17121.5 KKA02574.1 - 0.061 13.2 1.8 0.64 9.9 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 KKA02575.1 - 1.6e-58 197.5 0.1 1.6e-58 197.5 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKA02575.1 - 3.5e-14 52.6 0.0 1.9e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKA02575.1 - 2.6e-10 40.5 0.0 8.3e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKA02575.1 - 6.5e-07 29.3 0.0 2.4e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KKA02575.1 - 0.0027 17.8 0.0 0.012 15.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 KKA02575.1 - 0.03 14.1 2.8 0.086 12.6 0.0 2.7 3 0 0 3 3 3 0 Elongation factor G, domain IV Pkinase PF00069.25 KKA02576.1 - 1e-59 202.1 3.1 1.1e-41 143.0 0.2 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02576.1 - 2.7e-26 92.4 0.4 2e-20 73.2 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA02576.1 - 0.00068 18.7 8.0 0.0021 17.1 7.7 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKA02576.1 - 0.00087 18.7 1.7 0.0021 17.5 0.1 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKA02576.1 - 0.0017 18.3 0.2 0.36 10.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family UPF0180 PF03698.13 KKA02577.1 - 0.086 13.0 4.1 6.4 7.0 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) OST3_OST6 PF04756.13 KKA02578.1 - 4.2e-79 265.9 8.2 4.9e-79 265.7 8.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Deltameth_res PF16020.5 KKA02578.1 - 0.1 12.5 1.6 0.33 10.8 1.6 1.9 1 0 0 1 1 1 0 Deltamethrin resistance Thioredoxin PF00085.20 KKA02578.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF3341 PF11821.8 KKA02578.1 - 8.3 6.0 8.3 14 5.2 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF16 PF01519.16 KKA02579.1 - 0.0031 18.0 0.4 0.0031 18.0 0.4 4.7 5 1 0 5 5 5 2 Protein of unknown function DUF16 ArfGap PF01412.18 KKA02580.1 - 1.8e-33 115.0 8.1 3e-33 114.4 0.1 3.0 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Uteroglobin PF01099.17 KKA02580.1 - 0.76 10.1 0.0 0.76 10.1 0.0 2.5 3 0 0 3 3 3 0 Uteroglobin family zf-CCHC_5 PF14787.6 KKA02581.1 - 0.019 14.7 0.2 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HEPN_Apea PF18739.1 KKA02581.1 - 0.35 11.3 5.8 0.13 12.7 0.3 3.0 2 2 0 2 2 2 0 Apea-like HEPN zf-CCHC PF00098.23 KKA02581.1 - 0.55 10.4 2.4 1.2 9.4 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1947 PF09183.10 KKA02581.1 - 8.8 6.7 7.7 26 5.2 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Fungal_trans PF04082.18 KKA02582.1 - 1.3e-08 34.2 0.4 3.1e-08 33.0 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Nsp1_C PF05064.13 KKA02582.1 - 0.061 13.1 2.0 0.79 9.5 1.0 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Enolase_C PF00113.22 KKA02583.1 - 8.8e-149 494.6 0.0 1.2e-148 494.1 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KKA02583.1 - 4.1e-57 192.0 0.6 8.3e-57 191.0 0.6 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KKA02583.1 - 5.2e-06 26.2 0.1 1e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KKA02583.1 - 0.096 11.8 0.6 0.21 10.7 0.1 1.7 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DUF3726 PF12525.8 KKA02583.1 - 0.11 12.7 0.5 0.33 11.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) Proteasome PF00227.26 KKA02584.1 - 1.1e-52 178.3 0.2 1.6e-52 177.8 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKA02584.1 - 2.5e-11 43.0 0.1 4.6e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cwf_Cwc_15 PF04889.12 KKA02584.1 - 0.023 14.4 8.9 0.029 14.1 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 KKA02584.1 - 0.32 8.7 7.4 0.39 8.4 7.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_3_Rpc31 PF11705.8 KKA02584.1 - 0.47 10.7 15.8 0.62 10.3 15.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 KKA02584.1 - 0.84 9.6 8.7 1.3 9.0 8.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 KKA02584.1 - 2.1 7.4 15.5 2.4 7.2 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KKA02584.1 - 2.2 7.5 11.6 2.8 7.2 11.6 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKA02584.1 - 3.1 5.8 18.4 3.9 5.5 18.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 KKA02584.1 - 4.1 6.4 12.4 5.1 6.2 12.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KKA02584.1 - 9.5 4.4 10.1 11 4.2 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KKA02585.1 - 1.8e-42 145.5 0.2 1.2e-40 139.5 0.2 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02585.1 - 2.3e-21 76.3 0.0 9.1e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKA02585.1 - 0.035 12.9 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRR_4 PF12799.7 KKA02586.1 - 1e-34 117.9 56.5 5.5e-08 33.0 2.6 7.0 3 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKA02586.1 - 8.2e-28 96.0 45.0 5.1e-08 32.6 2.1 6.2 3 2 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KKA02586.1 - 1.2e-16 60.7 32.7 2.7e-09 36.8 6.6 4.7 1 1 3 4 4 4 4 Leucine-rich repeat Crystall_2 PF09076.10 KKA02586.1 - 0.00076 19.3 1.4 0.002 18.0 1.4 1.7 1 0 0 1 1 1 1 Beta/Gamma crystallin LRR_3 PF07725.12 KKA02586.1 - 0.032 14.1 0.1 0.032 14.1 0.1 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 KKA02586.1 - 0.048 13.7 37.6 0.38 10.9 0.3 9.4 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 KKA02586.1 - 0.073 13.7 45.2 8.5 7.4 0.5 10.9 11 1 0 11 11 11 0 Leucine Rich Repeat DUF2322 PF10084.9 KKA02586.1 - 3.4 7.8 7.4 19 5.4 0.2 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) tRNA-synt_2b PF00587.25 KKA02587.1 - 4.7e-40 137.5 0.0 7.6e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKA02587.1 - 3.4e-08 33.5 0.2 5.6e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain Synaptobrevin PF00957.21 KKA02588.1 - 1e-14 54.1 0.6 1.6e-14 53.4 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KKA02588.1 - 6.2e-10 39.0 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 KKA02588.1 - 0.084 12.7 0.8 0.98 9.2 0.3 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF1788 PF08747.11 KKA02588.1 - 0.11 12.4 0.9 0.4 10.7 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) WGG PF10273.9 KKA02591.1 - 3.7e-25 88.4 0.8 6.8e-25 87.5 0.8 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RNR_inhib PF08591.10 KKA02592.1 - 0.012 16.9 0.4 0.033 15.5 0.4 2.0 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor TFIIB PF00382.19 KKA02593.1 - 6.9e-51 170.2 0.3 1.1e-24 86.3 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KKA02593.1 - 1.7e-20 73.2 5.5 1.7e-20 73.2 5.5 3.0 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KKA02593.1 - 1.7e-09 37.1 2.9 3.3e-09 36.1 2.9 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KKA02593.1 - 0.00014 21.6 1.2 0.4 10.4 0.2 2.9 2 1 0 2 2 2 2 Cyclin, N-terminal domain Nudix_N_2 PF14803.6 KKA02593.1 - 0.21 11.5 2.0 1.9 8.5 1.0 2.9 2 1 0 2 2 2 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 KKA02593.1 - 0.4 10.8 1.1 0.89 9.7 1.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain RAC_head PF16717.5 KKA02594.1 - 2.6e-17 63.6 11.0 2.6e-17 63.6 11.0 3.5 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 KKA02594.1 - 2.1e-15 56.6 0.5 9.3e-15 54.5 0.5 2.2 1 0 0 1 1 1 1 DnaJ domain Nucleoporin2 PF04096.14 KKA02594.1 - 7.7 6.6 10.9 2.4 8.3 0.0 3.2 2 2 0 3 3 3 0 Nucleoporin autopeptidase SURF4 PF02077.15 KKA02595.1 - 6.2e-83 278.5 15.5 7.9e-83 278.1 15.5 1.1 1 0 0 1 1 1 1 SURF4 family Phage_holin_3_6 PF07332.11 KKA02595.1 - 1.7 8.7 13.2 0.84 9.7 0.2 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PIG-F PF06699.11 KKA02595.1 - 1.9 8.7 14.7 13 5.9 14.7 2.0 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F YjcB PF15940.5 KKA02595.1 - 3.1 8.0 6.5 0.37 11.0 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function IPP-2 PF04979.14 KKA02596.1 - 5.3e-12 46.6 17.6 1e-09 39.2 8.6 3.3 2 2 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Leucyl-specific PF14795.6 KKA02596.1 - 0.087 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain DUF2406 PF10295.9 KKA02597.1 - 5.3e-24 84.7 3.7 9.5e-23 80.7 1.9 2.6 2 1 0 2 2 2 1 Uncharacterised protein (DUF2406) Efg1 PF10153.9 KKA02598.1 - 2.7e-20 72.8 24.8 4e-20 72.3 19.1 2.9 2 1 0 2 2 2 1 rRNA-processing protein Efg1 Acetate_kinase PF00871.17 KKA02598.1 - 0.041 12.6 1.1 0.07 11.8 1.1 1.3 1 0 0 1 1 1 0 Acetokinase family GATase_6 PF13522.6 KKA02600.1 - 3e-12 46.9 0.0 7e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKA02600.1 - 2e-08 34.2 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KKA02600.1 - 3.9e-08 33.0 0.1 6.8e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KKA02600.1 - 0.00023 20.2 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II zf-met PF12874.7 KKA02601.1 - 2.1e-07 31.1 5.1 0.005 17.2 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKA02601.1 - 5.6e-07 29.9 7.7 0.0057 17.4 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKA02601.1 - 1e-06 28.8 8.3 0.0027 18.0 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KKA02601.1 - 3.1e-06 27.3 4.9 0.007 16.6 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KKA02601.1 - 0.0018 18.6 1.2 0.0018 18.6 1.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain Vps39_2 PF10367.9 KKA02601.1 - 0.0074 16.7 4.8 0.018 15.5 0.1 2.6 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-C2H2_11 PF16622.5 KKA02601.1 - 0.012 15.4 2.8 0.015 15.1 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KKA02601.1 - 0.016 15.2 4.3 1.5 8.9 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Plasmo_rep PF12135.8 KKA02601.1 - 0.096 12.2 0.7 0.096 12.2 0.7 2.5 2 0 0 2 2 2 0 Plasmodium repeat family C1_4 PF07975.12 KKA02601.1 - 0.48 10.7 4.2 3 8.1 0.2 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain FYVE PF01363.21 KKA02601.1 - 2.4 8.4 6.0 25 5.1 0.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger Proteasome PF00227.26 KKA02602.1 - 2.1e-42 144.8 0.1 2.5e-42 144.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKA02602.1 - 8.2e-13 47.8 0.1 1.9e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PG_binding_4 PF12229.8 KKA02602.1 - 0.022 15.1 0.4 3.6 7.9 0.0 2.9 2 1 0 2 2 2 0 Putative peptidoglycan binding domain Aminotran_1_2 PF00155.21 KKA02603.1 - 6.1e-40 137.5 0.0 8e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKA02603.1 - 0.059 11.9 0.0 0.099 11.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Amidase PF01425.21 KKA02604.1 - 4.4e-82 276.4 0.0 5.5e-63 213.5 0.0 2.1 2 0 0 2 2 2 2 Amidase Pept_tRNA_hydro PF01195.19 KKA02605.1 - 2e-24 86.4 0.1 5.8e-24 85.0 0.1 1.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase RTT107_BRCT_5 PF16770.5 KKA02606.1 - 1.7e-05 24.6 0.1 0.00012 21.9 0.1 2.6 1 1 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Kelch_5 PF13854.6 KKA02607.1 - 1.5e-30 104.6 2.0 8.9e-06 25.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KKA02607.1 - 3.4e-29 100.6 6.4 1.3e-07 31.5 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KKA02607.1 - 3.7e-25 87.3 4.4 1.6e-07 31.4 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KKA02607.1 - 2e-23 82.1 1.0 0.00042 20.5 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KKA02607.1 - 3.6e-19 68.1 4.9 3.9e-09 36.0 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KKA02607.1 - 3.8e-16 58.4 7.7 0.002 18.0 0.0 7.0 6 1 0 6 6 6 4 Kelch motif DUF3450 PF11932.8 KKA02607.1 - 1 8.6 6.2 0.81 8.9 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 KKA02607.1 - 2.7 8.1 9.0 0.16 12.1 1.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor TDA11 PF17084.5 KKA02608.1 - 1.5e-06 27.4 27.1 0.00019 20.5 4.2 2.4 2 0 0 2 2 2 2 Topoisomerase I damage affected protein 11 ATG16 PF08614.11 KKA02608.1 - 0.003 17.8 5.7 0.003 17.8 5.7 2.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KKA02608.1 - 0.038 13.1 11.5 0.21 10.6 6.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AMP-binding_C_2 PF14535.6 KKA02608.1 - 0.77 10.1 3.7 32 4.9 0.1 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF16 PF01519.16 KKA02608.1 - 2.2 8.8 10.6 1.5 9.3 5.1 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KKA02608.1 - 3.1 7.1 5.7 5.5 6.3 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PFK PF00365.20 KKA02610.1 - 3.4e-186 617.2 1.5 1.6e-103 345.9 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KKA02610.1 - 0.026 14.1 0.2 0.085 12.5 0.2 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Peptidase_S10 PF00450.22 KKA02611.1 - 8.1e-103 345.0 0.3 8.1e-103 345.0 0.3 1.4 2 0 0 2 2 2 1 Serine carboxypeptidase Ring_hydroxyl_B PF00866.18 KKA02611.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Methyltrn_RNA_3 PF02598.17 KKA02612.1 - 6.1e-55 186.7 1.7 6.1e-55 186.7 1.7 1.4 2 0 0 2 2 2 1 Putative RNA methyltransferase Glyco_hydro_17 PF00332.18 KKA02613.1 - 2.3e-49 168.7 1.2 2.8e-49 168.4 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Utp21 PF04192.12 KKA02614.1 - 7.7e-32 110.7 6.9 1.3e-31 110.0 6.9 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KKA02614.1 - 1.8e-10 41.0 1.2 6.1e-07 29.7 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKA02614.1 - 7.1e-10 39.3 0.9 2e-06 28.4 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KKA02614.1 - 0.00036 19.2 5.0 0.0023 16.6 0.2 3.5 4 0 0 4 4 4 1 Cytochrome D1 heme domain Utp12 PF04003.12 KKA02614.1 - 0.038 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF4448 PF14610.6 KKA02617.1 - 9.5e-43 146.2 1.7 1.9e-42 145.2 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1533 PF07550.11 KKA02618.1 - 0.027 14.4 1.4 0.027 14.4 1.4 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1533) GD_N PF16030.5 KKA02618.1 - 0.061 13.6 1.5 0.36 11.2 0.4 2.6 2 0 0 2 2 2 0 Serine protease gd N-terminus FAD_SOX PF18371.1 KKA02618.1 - 0.12 12.7 3.4 0.14 12.5 0.9 2.3 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Y_phosphatase3 PF13350.6 KKA02619.1 - 2.7e-22 79.9 0.0 1.9e-21 77.1 0.0 2.2 2 1 0 2 2 2 1 Tyrosine phosphatase family Abhydrolase_1 PF00561.20 KKA02619.1 - 4.4e-05 23.3 0.1 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA02619.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ank_4 PF13637.6 KKA02620.1 - 7e-07 29.7 0.0 0.0018 18.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA02620.1 - 6e-06 26.2 0.6 0.0015 18.9 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KKA02620.1 - 3.4e-05 23.7 7.3 0.00011 22.0 0.2 3.8 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.30 KKA02620.1 - 0.00017 21.9 1.1 0.26 11.8 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KKA02620.1 - 0.00034 21.1 0.5 0.2 12.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) NTP_transferase PF00483.23 KKA02621.1 - 1e-55 189.0 0.0 1.7e-55 188.3 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KKA02621.1 - 3.7e-11 43.6 0.0 5.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KKA02621.1 - 1.3e-08 34.2 10.0 7e-07 28.7 1.0 3.8 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KKA02621.1 - 0.0023 16.2 0.7 0.0035 15.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KKA02621.1 - 0.013 15.2 7.7 0.35 10.7 0.5 3.7 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 KKA02621.1 - 0.091 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 KKA02621.1 - 0.14 11.1 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase NopRA1 PF16201.5 KKA02622.1 - 0.093 12.3 3.5 1.1 8.8 0.1 3.6 4 0 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 RsfS PF02410.15 KKA02623.1 - 0.00069 20.0 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Tna_leader PF08053.11 KKA02623.1 - 0.13 12.3 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Tryptophanase operon leader peptide 7TM_GPCR_Srw PF10324.9 KKA02624.1 - 0.29 10.3 5.5 0.46 9.7 5.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Pkinase PF00069.25 KKA02625.1 - 1.5e-52 178.6 2.6 3.4e-52 177.4 2.6 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02625.1 - 4.5e-27 95.0 0.8 5.1e-26 91.5 0.8 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02625.1 - 7e-05 22.3 0.0 0.0048 16.2 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKA02625.1 - 0.0002 20.3 0.1 0.00051 18.9 0.1 1.6 1 0 0 1 1 1 1 Fungal protein kinase Baculo_19 PF04798.12 KKA02625.1 - 0.02 14.6 0.5 0.071 12.8 0.3 2.1 1 1 0 1 1 1 0 Baculovirus 19 kDa protein conserved region FTA2 PF13095.6 KKA02625.1 - 0.05 13.2 0.6 1.2 8.7 0.2 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Snf7 PF03357.21 KKA02626.1 - 2.2e-11 43.7 25.5 2.2e-11 43.7 25.5 2.1 1 1 1 2 2 2 1 Snf7 Effector_1 PF04518.12 KKA02626.1 - 1.6 7.7 19.5 0.007 15.5 8.3 1.9 1 1 1 2 2 2 0 Effector from type III secretion system Suf PF05843.14 KKA02627.1 - 0.0031 17.6 0.2 0.0031 17.6 0.2 3.4 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) Glyco_hydro_28 PF00295.17 KKA02627.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 CLAMP PF14769.6 KKA02627.1 - 0.18 12.3 3.8 3.1 8.3 0.2 3.7 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 TFIIA_gamma_N PF02268.16 KKA02628.1 - 1.5e-21 76.1 0.2 2.7e-21 75.3 0.1 1.5 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KKA02628.1 - 9.8e-20 70.4 0.1 2.3e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Alkyl_sulf_C PF14864.6 KKA02628.1 - 0.0022 18.3 0.3 0.13 12.6 0.0 2.2 1 1 1 2 2 2 2 Alkyl sulfatase C-terminal TAP42 PF04177.12 KKA02629.1 - 7.2e-22 77.9 24.6 1.1e-21 77.4 24.6 1.2 1 0 0 1 1 1 1 TAP42-like family DEAD PF00270.29 KKA02631.1 - 5.5e-50 169.6 0.1 6.5e-49 166.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02631.1 - 1.9e-25 89.3 0.0 5e-24 84.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKA02631.1 - 5.7e-19 68.1 0.1 1.2e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKA02631.1 - 7.1e-08 32.6 0.0 2.8e-07 30.7 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKA02631.1 - 0.00054 19.2 0.0 0.00099 18.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 KKA02631.1 - 0.046 13.0 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain NACHT PF05729.12 KKA02631.1 - 0.12 12.3 0.3 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KKA02631.1 - 0.18 12.1 0.7 0.82 9.9 0.7 2.3 1 1 0 1 1 1 0 AAA domain tRNA-synt_1g PF09334.11 KKA02632.1 - 3e-156 520.1 1.3 4e-156 519.7 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKA02632.1 - 6.1e-11 41.3 0.3 6.4e-06 24.7 0.0 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) MetRS-N PF09635.10 KKA02632.1 - 5.1e-06 27.0 0.3 1.4e-05 25.6 0.3 1.7 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1e PF01406.19 KKA02632.1 - 0.0015 17.9 0.2 0.011 15.1 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Toprim_N PF08275.11 KKA02632.1 - 0.11 12.5 0.5 9.2 6.3 0.0 2.7 2 0 0 2 2 2 0 DNA primase catalytic core, N-terminal domain Kdo PF06293.14 KKA02633.1 - 4.8e-09 35.9 0.1 9e-09 35.0 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KKA02633.1 - 3e-05 23.5 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 KKA02633.1 - 4.5e-05 22.9 0.4 6.2e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 KKA02633.1 - 6.4e-05 22.4 0.1 7.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKA02633.1 - 8.5e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKA02633.1 - 0.00067 19.3 0.4 0.0018 17.9 0.1 1.9 1 1 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 KKA02633.1 - 0.012 14.5 0.2 0.018 14.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Elong_Iki1 PF10483.9 KKA02634.1 - 1.3e-45 156.2 2.6 1.6e-45 155.9 2.6 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 zf-met PF12874.7 KKA02635.1 - 0.00082 19.7 1.6 0.00082 19.7 1.6 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KKA02635.1 - 0.0061 17.0 0.8 0.0061 17.0 0.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA02635.1 - 0.017 15.5 9.0 0.032 14.7 0.2 3.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA02635.1 - 0.034 15.0 1.0 0.034 15.0 1.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKA02635.1 - 0.082 13.2 0.5 0.082 13.2 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KKA02635.1 - 0.12 12.7 17.4 0.069 13.5 4.5 3.0 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KKA02635.1 - 0.18 11.6 11.1 0.15 11.8 2.2 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain OTT_1508_deam PF14441.6 KKA02635.1 - 3 7.9 7.4 1.2 9.2 0.3 2.5 1 1 1 2 2 2 0 OTT_1508-like deaminase zf-H2C2_2 PF13465.6 KKA02636.1 - 3.2e-05 24.2 5.6 3.2e-05 24.2 5.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKA02636.1 - 6.6e-05 23.1 13.3 0.00061 20.1 0.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKA02636.1 - 0.00031 21.3 11.1 0.00097 19.8 0.5 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KKA02636.1 - 0.003 17.9 0.8 0.003 17.9 0.8 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKA02636.1 - 0.028 14.7 1.0 0.028 14.7 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NUC173 PF08161.12 KKA02637.1 - 0.00016 21.4 0.3 0.97 9.0 0.0 4.0 4 0 0 4 4 4 2 NUC173 domain UME PF08064.13 KKA02637.1 - 0.00039 20.3 0.1 7.2 6.6 0.0 4.8 4 1 0 4 4 4 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KKA02637.1 - 0.0023 18.5 5.4 28 5.4 0.1 5.7 5 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KKA02637.1 - 0.0029 17.7 6.9 4.2 7.9 0.1 6.0 6 0 0 6 6 6 1 HEAT repeat PSY3 PF16836.5 KKA02638.1 - 3.6e-05 23.4 11.0 0.0024 17.4 11.0 2.6 1 1 0 1 1 1 1 Shu complex component Psy3, DNA-binding description zf-C2H2_4 PF13894.6 KKA02639.1 - 2.4e-05 24.8 23.6 0.0011 19.6 1.2 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KKA02639.1 - 0.00039 20.7 2.1 0.00039 20.7 2.1 5.0 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KKA02639.1 - 0.0084 16.4 0.3 0.0084 16.4 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KKA02639.1 - 0.012 16.0 0.5 0.012 16.0 0.5 4.4 3 2 1 4 4 4 0 Zinc-finger double domain zf-C2H2_12 PF18658.1 KKA02639.1 - 8.8 6.0 8.0 23 4.7 0.4 3.6 3 1 1 4 4 4 0 Zinc-finger C2H2-type PAP_central PF04928.17 KKA02641.1 - 0.0015 17.6 3.9 0.0015 17.6 3.9 2.3 2 1 0 2 2 2 1 Poly(A) polymerase central domain TEX13 PF15186.6 KKA02641.1 - 3.1 7.5 14.1 0.32 10.7 2.4 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Yae1_N PF09811.9 KKA02642.1 - 5e-05 22.9 1.8 7.6e-05 22.3 1.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal p450 PF00067.22 KKA02643.1 - 1.3e-50 172.5 0.0 1.7e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UCH PF00443.29 KKA02644.1 - 3.8e-43 147.9 5.6 3.8e-43 147.9 5.6 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KKA02644.1 - 5.2e-29 101.4 6.9 5.2e-29 101.4 6.9 2.9 3 1 1 4 4 4 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 KKA02644.1 - 5.7e-13 49.1 1.3 5.7e-13 49.1 1.3 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KKA02644.1 - 2.3e-12 46.7 3.0 6.4e-12 45.3 3.0 1.7 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.26 KKA02644.1 - 7.5e-06 26.1 1.0 7.8e-05 22.8 0.1 3.3 2 1 0 2 2 2 1 MATH domain CompInhib_SCIN PF11546.8 KKA02644.1 - 0.041 13.9 1.0 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN CTP_transf_like PF01467.26 KKA02645.1 - 2.4e-06 27.8 0.0 6.2e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like MA3 PF02847.17 KKA02646.1 - 4.8e-08 33.0 1.1 1.4e-07 31.4 1.1 1.9 1 0 0 1 1 1 1 MA3 domain NusB PF01029.18 KKA02646.1 - 0.096 12.9 3.4 0.14 12.4 0.6 2.6 2 1 0 2 2 2 0 NusB family Glucan_synthase PF02364.15 KKA02647.1 - 0 1257.0 14.0 0 1256.1 14.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KKA02647.1 - 6.5e-45 152.6 1.7 2.7e-44 150.6 1.7 2.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NDT80_PhoG PF05224.12 KKA02647.1 - 1.9 8.7 6.2 5.6 7.1 6.2 1.8 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Glyco_hydro_72 PF03198.14 KKA02648.1 - 1e-142 475.1 13.2 1.5e-142 474.5 13.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKA02648.1 - 1.7e-22 79.8 2.9 8.6e-22 77.6 2.9 2.3 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KKA02648.1 - 5.1e-07 29.1 3.0 1.1e-06 28.0 3.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain zf-ZPR1 PF03367.13 KKA02649.1 - 3e-78 261.2 12.5 1.1e-46 158.6 1.1 3.6 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KKA02649.1 - 0.00099 19.1 2.2 0.08 13.0 0.1 2.7 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4889 PF16230.5 KKA02649.1 - 5.7 7.2 7.9 4.1 7.7 0.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4889) MRP-S33 PF08293.11 KKA02650.1 - 8.1e-21 74.1 0.2 1.2e-20 73.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 TPP_enzyme_N PF02776.18 KKA02651.1 - 3.2e-34 118.0 0.1 5.5e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKA02651.1 - 5.2e-28 97.5 0.0 1.5e-25 89.5 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKA02651.1 - 2.9e-12 46.6 0.0 5.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 KKA02651.1 - 0.1 12.7 0.1 6 7.1 0.0 2.6 2 0 0 2 2 2 0 OCC1 family Abhydrolase_1 PF00561.20 KKA02651.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SKG6 PF08693.10 KKA02652.1 - 5.4e-05 22.5 5.0 9.6e-05 21.7 5.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain 7TM_GPCR_Str PF10326.9 KKA02652.1 - 0.00071 19.0 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DUF4519 PF15012.6 KKA02652.1 - 0.0025 17.9 0.7 0.0077 16.4 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.6 KKA02652.1 - 0.015 15.1 2.4 0.03 14.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 KKA02652.1 - 0.033 14.5 0.1 0.033 14.5 0.1 3.7 3 1 1 4 4 4 0 Orf78 (ac78) Syndecan PF01034.20 KKA02652.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Syndecan domain DUF1542 PF07564.11 KKA02652.1 - 0.67 10.1 19.6 18 5.5 0.6 4.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) SRP_SPB PF02978.19 KKA02652.1 - 0.88 10.2 4.8 0.72 10.5 0.6 2.9 2 1 0 2 2 2 0 Signal peptide binding domain DUF4834 PF16118.5 KKA02652.1 - 2.7 9.0 0.0 2.7 9.0 0.0 4.3 4 2 0 4 4 4 0 Domain of unknown function (DUF4834) S4 PF01479.25 KKA02653.1 - 5.9e-09 35.5 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KKA02653.1 - 0.0005 20.9 0.5 0.0005 20.9 0.5 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L6 PF00347.23 KKA02654.1 - 1.7e-09 38.2 0.0 0.011 16.4 0.0 3.8 3 1 1 4 4 4 3 Ribosomal protein L6 Utp11 PF03998.13 KKA02655.1 - 3.2e-64 217.2 37.7 3.7e-64 217.0 37.7 1.0 1 0 0 1 1 1 1 Utp11 protein CRC_subunit PF08624.10 KKA02657.1 - 5.7e-32 111.0 1.6 7.9e-32 110.5 0.4 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Bro-N PF02498.17 KKA02657.1 - 0.013 16.2 0.1 0.057 14.1 0.1 2.2 1 0 0 1 1 1 0 BRO family, N-terminal domain Peptidase_M41 PF01434.18 KKA02658.1 - 5.6e-64 215.5 0.0 1.1e-63 214.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KKA02658.1 - 5.2e-41 140.2 0.0 1.3e-40 138.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA02658.1 - 1.1e-14 53.9 0.3 2.8e-14 52.6 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KKA02658.1 - 0.00067 19.9 0.1 0.89 9.8 0.1 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KKA02658.1 - 0.0023 17.7 0.0 0.0078 16.0 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKA02658.1 - 0.011 16.2 0.3 0.22 11.9 0.2 2.6 1 1 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 KKA02658.1 - 0.022 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KKA02658.1 - 0.025 14.3 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KKA02658.1 - 0.048 13.7 0.2 0.29 11.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKA02658.1 - 0.065 13.3 0.1 0.31 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) hGDE_central PF14702.6 KKA02658.1 - 0.19 11.3 2.8 0.56 9.8 2.8 1.7 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme DUF5595 PF18077.1 KKA02658.1 - 5.5 7.1 8.5 8.7 6.5 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF5595) MFS_1 PF07690.16 KKA02659.1 - 7.4e-35 120.5 31.4 3.8e-34 118.2 31.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA02659.1 - 2.8e-21 75.9 7.9 2.8e-21 75.9 7.9 3.3 4 0 0 4 4 4 1 Sugar (and other) transporter SIS PF01380.22 KKA02660.1 - 6e-63 210.5 0.0 2e-34 118.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KKA02660.1 - 7.1e-16 58.6 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKA02660.1 - 3.6e-10 39.8 0.0 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KKA02660.1 - 0.00036 19.5 0.0 0.00062 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KKA02660.1 - 0.0071 15.1 0.1 0.22 10.2 0.1 2.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Aldose_epim PF01263.20 KKA02661.1 - 3.2e-41 141.6 0.1 3.6e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase HSP70 PF00012.20 KKA02662.1 - 7.2e-44 150.0 9.4 7.2e-44 150.0 9.4 2.2 2 0 0 2 2 2 1 Hsp70 protein DUF4373 PF14297.6 KKA02662.1 - 4.4 8.2 8.2 1.5 9.6 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4373) Peptidase_M18 PF02127.15 KKA02663.1 - 1.6e-129 432.5 0.0 1.8e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Proteasom_Rpn13 PF04683.13 KKA02664.1 - 9.7e-08 32.5 0.0 1.4e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ABC_membrane PF00664.23 KKA02665.1 - 1.4e-54 185.7 49.2 1.6e-29 103.4 27.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKA02665.1 - 2.2e-42 144.8 2.5 1.2e-30 106.8 0.1 3.8 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.19 KKA02665.1 - 6.3e-12 45.4 0.0 0.0012 18.3 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKA02665.1 - 3.9e-07 29.7 0.2 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKA02665.1 - 1.5e-06 28.2 0.3 0.023 14.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 KKA02665.1 - 4.1e-05 22.9 0.4 0.36 10.0 0.0 3.0 2 1 0 2 2 2 2 NB-ARC domain AAA_21 PF13304.6 KKA02665.1 - 4.7e-05 23.3 6.5 1.3 8.7 0.1 4.9 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKA02665.1 - 0.00043 20.7 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KKA02665.1 - 0.0019 18.3 0.2 0.65 10.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KKA02665.1 - 0.002 17.7 0.3 1.4 8.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KKA02665.1 - 0.0025 17.2 0.3 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SSE PF00437.20 KKA02665.1 - 0.0025 16.9 0.2 0.013 14.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.6 KKA02665.1 - 0.0035 17.6 0.2 2.3 8.5 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KKA02665.1 - 0.006 16.9 8.5 0.28 11.5 0.2 3.6 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KKA02665.1 - 0.0085 15.8 0.2 3.7 7.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKA02665.1 - 0.0086 15.8 0.5 7.1 6.3 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 KKA02665.1 - 0.012 16.2 0.2 3.4 8.2 0.1 3.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KKA02665.1 - 0.015 15.0 0.0 2.5 7.8 0.0 2.9 4 0 0 4 4 3 0 Sigma-54 interaction domain Vps51 PF08700.11 KKA02665.1 - 0.018 15.1 0.6 0.062 13.4 0.1 2.2 2 0 0 2 2 1 0 Vps51/Vps67 AAA_23 PF13476.6 KKA02665.1 - 0.021 15.3 0.2 0.021 15.3 0.2 4.2 5 0 0 5 5 4 0 AAA domain AAA_14 PF13173.6 KKA02665.1 - 0.023 14.7 2.0 2.4 8.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KKA02665.1 - 0.026 14.4 0.3 1.6 8.7 0.1 2.8 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KKA02665.1 - 0.026 14.3 0.3 3.7 7.3 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KH_2 PF07650.17 KKA02665.1 - 0.04 13.7 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 1 0 KH domain Roc PF08477.13 KKA02665.1 - 0.045 14.0 0.3 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KKA02665.1 - 0.046 14.0 2.0 0.54 10.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KKA02665.1 - 0.048 13.4 0.1 9.5 5.9 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KKA02665.1 - 0.067 13.6 0.2 20 5.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KKA02665.1 - 0.076 13.2 0.1 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKA02665.1 - 0.092 12.4 0.4 13 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 KKA02665.1 - 0.12 11.9 0.1 17 4.9 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KKA02665.1 - 0.16 12.0 0.2 20 5.2 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KKA02665.1 - 0.17 11.8 0.9 5.5 6.9 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 KKA02665.1 - 0.22 11.6 7.3 5.8 6.9 0.0 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain cobW PF02492.19 KKA02665.1 - 0.23 11.0 1.0 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KKA02665.1 - 0.34 10.9 6.3 2.9 7.9 0.1 3.0 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KKA02665.1 - 0.74 9.7 13.1 1.9 8.3 0.1 4.6 4 2 1 5 5 5 0 ATPase domain predominantly from Archaea Glyco_hydro_47 PF01532.20 KKA02666.1 - 3.6e-10 39.3 1.3 5.5e-05 22.2 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 TMV_coat PF00721.21 KKA02667.1 - 0.00013 21.8 0.1 0.00021 21.2 0.1 1.4 1 0 0 1 1 1 1 Virus coat protein (TMV like) zf-C2HE PF16278.5 KKA02667.1 - 0.031 14.7 0.3 0.14 12.7 0.3 2.3 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger MM_CoA_mutase PF01642.22 KKA02667.1 - 0.074 11.6 0.1 0.093 11.3 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase SLATT_fungal PF18142.1 KKA02667.1 - 0.12 12.4 0.4 3.5 7.7 0.0 2.6 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Sas10_Utp3 PF04000.15 KKA02667.1 - 1.2 9.8 6.5 0.45 11.2 1.5 2.7 2 1 0 2 2 2 0 Sas10/Utp3/C1D family NAC PF01849.18 KKA02668.1 - 4.9e-07 29.6 0.3 1.2e-06 28.4 0.1 1.9 2 0 0 2 2 2 1 NAC domain 5-FTHF_cyc-lig PF01812.20 KKA02669.1 - 1.7e-22 80.2 0.0 5.9e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family DUF2680 PF10925.8 KKA02669.1 - 0.032 14.2 2.1 3.2 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF4462 PF14692.6 KKA02669.1 - 0.22 11.0 0.3 0.47 10.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Acetyltransf_19 PF18015.1 KKA02669.1 - 1.2 9.4 5.7 17 5.7 0.3 3.5 3 1 1 4 4 4 0 Acetyltransferase (GNAT) domain CxC2 PF18803.1 KKA02670.1 - 0.042 14.0 1.0 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases zf-MYND PF01753.18 KKA02670.1 - 2.3 8.4 12.8 5.7 7.1 12.8 1.7 1 1 0 1 1 1 0 MYND finger Pkinase PF00069.25 KKA02671.1 - 4.5e-62 209.8 0.1 5.1e-51 173.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02671.1 - 3.6e-28 98.6 0.3 2.4e-26 92.6 0.3 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02671.1 - 1.4e-09 37.7 0.0 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_C PF00433.24 KKA02671.1 - 1.7e-06 28.7 7.1 1.8e-05 25.4 7.1 2.7 1 1 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KKA02671.1 - 0.00094 18.9 0.1 0.022 14.4 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KKA02671.1 - 0.0016 17.4 1.7 0.0037 16.3 1.7 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Coq4 PF05019.13 KKA02671.1 - 0.0065 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 YrbL-PhoP_reg PF10707.9 KKA02671.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PMT PF02366.18 KKA02672.1 - 2e-69 233.9 18.8 2e-69 233.9 18.8 1.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKA02672.1 - 8.1e-59 198.6 12.4 8.1e-59 198.6 12.4 3.1 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKA02672.1 - 8.9e-05 22.4 0.1 0.0002 21.3 0.1 1.5 1 0 0 1 1 1 1 MIR domain HECT_2 PF09814.9 KKA02673.1 - 1.3e-28 99.9 0.3 1.6e-28 99.6 0.3 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 KKA02673.1 - 0.093 13.0 0.5 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly c-SKI_SMAD_bind PF08782.10 KKA02673.1 - 0.96 9.7 4.5 4.4 7.6 0.0 2.7 2 1 0 2 2 2 0 c-SKI Smad4 binding domain ACD PF16671.5 KKA02675.1 - 0.024 13.0 0.4 5.4 5.2 0.1 2.9 3 0 0 3 3 3 0 Actin cross-linking domain Chalcone_2 PF16035.5 KKA02676.1 - 4.8e-30 104.9 0.2 5.5e-28 98.1 0.2 2.1 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KKA02676.1 - 0.079 13.1 0.1 0.23 11.5 0.1 1.9 1 1 0 1 1 1 0 Chalcone isomerase-like Tti2 PF10521.9 KKA02677.1 - 9e-06 25.4 2.7 1.4e-05 24.7 2.7 1.6 1 1 0 1 1 1 1 Tti2 family DUF383 PF04063.14 KKA02678.1 - 4.8e-57 192.7 4.7 5.7e-57 192.5 0.9 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KKA02678.1 - 1.1e-20 73.2 1.0 4.4e-20 71.3 1.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DsrC PF04358.13 KKA02678.1 - 0.04 14.4 0.0 12 6.5 0.0 2.7 2 1 0 2 2 2 0 DsrC like protein tRNA-synt_1b PF00579.25 KKA02679.1 - 5.4e-77 259.0 0.1 9.7e-77 258.2 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Methyltrans_Mon PF14314.6 KKA02679.1 - 0.14 10.2 0.0 0.83 7.6 0.0 1.9 2 0 0 2 2 2 0 Virus-capping methyltransferase zf-UBR PF02207.20 KKA02680.1 - 9.4e-19 67.4 9.9 9.4e-19 67.4 9.9 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KKA02680.1 - 0.00014 21.6 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RRN7 PF11781.8 KKA02681.1 - 4.1e-06 26.4 0.7 6.8e-06 25.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF573 PF04504.14 KKA02681.1 - 1 10.1 9.8 4.6 8.0 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF573 SE PF08491.10 KKA02682.1 - 4e-112 373.8 0.0 5.8e-112 373.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KKA02682.1 - 3.1e-14 53.0 0.0 1.8e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKA02682.1 - 0.00011 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKA02682.1 - 0.0019 18.4 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KKA02682.1 - 0.0024 17.9 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KKA02682.1 - 0.003 17.5 0.1 0.0049 16.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KKA02682.1 - 0.01 15.0 0.2 0.015 14.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KKA02682.1 - 0.018 15.6 0.1 0.051 14.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKA02682.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKA02682.1 - 0.043 13.1 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GDI PF00996.18 KKA02682.1 - 0.062 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.16 KKA02682.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KKA02682.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KKA02682.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 KKA02682.1 - 0.21 10.2 0.3 0.34 9.5 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Clat_adaptor_s PF01217.20 KKA02683.1 - 1.8e-38 131.6 0.1 2.4e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SPC25 PF06703.11 KKA02684.1 - 3.6e-07 30.1 6.2 6.5e-07 29.3 6.2 1.5 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) LPD11 PF18824.1 KKA02684.1 - 0.13 12.4 1.7 0.55 10.3 0.3 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 ParcG PF10274.9 KKA02685.1 - 0.23 11.5 3.3 1.6 8.8 0.4 3.2 2 2 0 2 2 2 0 Parkin co-regulated protein PMP22_Claudin PF00822.20 KKA02685.1 - 2.4 8.0 14.0 0.058 13.3 5.3 2.6 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 KKA02686.1 - 1e-13 51.4 11.8 1.2e-13 51.2 11.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family TMEM247 PF15444.6 KKA02686.1 - 0.054 13.5 0.9 0.082 12.9 0.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 DUF4199 PF13858.6 KKA02686.1 - 1.9 8.8 14.9 3.3 8.1 14.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Colicin_V PF02674.16 KKA02686.1 - 3.1 7.8 15.8 6.9 6.6 8.3 2.4 1 1 1 2 2 2 0 Colicin V production protein GATA PF00320.27 KKA02687.1 - 2.7e-08 33.3 12.2 5.3e-08 32.3 8.0 2.7 2 0 0 2 2 2 1 GATA zinc finger DUF4984 PF16372.5 KKA02687.1 - 0.05 13.5 0.8 0.31 10.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4984) Voldacs PF03517.13 KKA02688.1 - 1.3e-06 28.6 0.2 2e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1729 PF08354.10 KKA02689.1 - 1.2e-152 507.9 0.0 2e-152 507.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKA02689.1 - 1.1e-98 330.8 0.0 1.9e-97 326.6 0.0 2.9 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KKA02689.1 - 5e-43 146.4 0.0 1.5e-42 144.8 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 KKA02689.1 - 5.1e-38 129.4 0.2 9.8e-38 128.5 0.2 1.5 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KKA02689.1 - 1.3e-33 116.7 0.0 2.9e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 KKA02689.1 - 1.2e-24 86.7 1.5 4.8e-24 84.8 1.5 2.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KKA02689.1 - 2.1e-12 47.3 0.0 7.3e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase His_biosynth PF00977.21 KKA02689.1 - 0.16 11.4 0.1 5.6 6.3 0.1 2.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Pribosyltran_N PF13793.6 KKA02690.1 - 1.8e-39 134.3 0.0 4.5e-39 133.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKA02690.1 - 1.1e-37 129.9 0.1 1.3e-29 103.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKA02690.1 - 5.6e-06 26.0 0.1 0.0048 16.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain NOA36 PF06524.12 KKA02690.1 - 1.5 8.1 5.2 2.2 7.5 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Copper-fist PF00649.18 KKA02691.1 - 1.3e-18 66.2 3.8 1.3e-18 66.2 3.8 2.4 3 0 0 3 3 3 1 Copper fist DNA binding domain Amino_oxidase PF01593.24 KKA02692.1 - 5.6e-32 111.6 0.0 8.2e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKA02692.1 - 3.4e-07 30.4 0.0 8.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phage_TAC_8 PF10666.9 KKA02692.1 - 0.33 11.2 5.8 0.26 11.6 3.5 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 Amino_oxidase PF01593.24 KKA02693.1 - 3.4e-35 122.2 0.0 3.7e-34 118.8 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKA02693.1 - 6.7e-09 35.8 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKA02693.1 - 0.0056 16.7 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KKA02693.1 - 0.012 14.8 0.2 0.033 13.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KKA02693.1 - 0.012 14.8 0.7 0.25 10.5 0.7 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKA02693.1 - 0.028 13.7 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KKA02693.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCRA PF06100.11 KKA02693.1 - 0.046 12.5 1.4 0.046 12.5 0.1 1.6 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 KKA02693.1 - 0.048 12.4 0.3 0.34 9.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KKA02693.1 - 0.074 13.6 1.0 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PRiA4_ORF3 PF07929.11 KKA02693.1 - 0.087 12.5 0.3 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein Pyr_redox_3 PF13738.6 KKA02693.1 - 0.19 11.0 0.7 12 5.0 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNB PF00773.19 KKA02694.1 - 1.8e-36 126.1 16.5 1.7e-35 122.9 13.8 2.8 2 1 0 2 2 2 1 RNB domain Cullin_Nedd8 PF10557.9 KKA02694.1 - 0.038 14.0 0.0 0.15 12.1 0.0 2.1 1 0 0 1 1 1 0 Cullin protein neddylation domain DNA_primase_lrg PF04104.14 KKA02695.1 - 1.1e-66 225.0 8.0 1.1e-66 225.0 8.0 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit P21-Arc PF04062.14 KKA02696.1 - 5e-48 163.4 5.8 2e-47 161.5 5.8 1.7 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Clathrin_lg_ch PF01086.17 KKA02698.1 - 7.4e-34 117.8 23.9 8.9e-34 117.5 23.9 1.1 1 0 0 1 1 1 1 Clathrin light chain PdaC PF13739.6 KKA02698.1 - 4.6 8.3 11.9 15 6.6 6.3 2.3 2 0 0 2 2 2 0 Deacetylase PdaC DUF2407_C PF13373.6 KKA02698.1 - 4.9 7.3 9.2 11 6.2 9.2 1.8 1 1 0 1 1 1 0 DUF2407 C-terminal domain LsmAD PF06741.13 KKA02700.1 - 1.1e-16 61.1 2.6 1.1e-16 61.1 2.6 2.0 2 0 0 2 2 2 1 LsmAD domain CDC73_C PF05179.14 KKA02701.1 - 8.2e-44 149.1 4.9 1.7e-43 148.0 4.9 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KKA02701.1 - 0.0088 15.4 2.3 0.032 13.6 0.2 2.3 1 1 0 2 2 2 1 Paf1 complex subunit CDC73 N-terminal Allantoicase PF03561.15 KKA02702.1 - 1.1e-74 249.2 0.0 4.9e-37 127.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Amidohydro_1 PF01979.20 KKA02704.1 - 2e-05 24.1 0.0 4.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KKA02704.1 - 5.9e-05 23.0 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase UQ_con PF00179.26 KKA02705.1 - 1.5e-46 157.5 0.0 1.7e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 KKA02705.1 - 0.023 14.4 0.1 0.041 13.5 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 KKA02705.1 - 0.48 10.7 2.1 0.55 10.5 0.3 1.9 1 1 1 2 2 2 0 RWD domain Glyco_hydro_76 PF03663.14 KKA02706.1 - 1.1e-151 505.5 25.7 1.3e-151 505.3 25.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Pantoate_transf PF02548.15 KKA02707.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase dsrm PF00035.26 KKA02708.1 - 1.6e-09 38.3 0.0 4.3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KKA02708.1 - 0.075 13.2 1.1 0.68 10.1 0.1 2.8 2 1 0 2 2 2 0 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KKA02708.1 - 0.18 12.5 0.5 3.8 8.2 0.1 2.7 1 1 1 2 2 2 0 Ribonuclease III domain F_bP_aldolase PF01116.20 KKA02709.1 - 2.8e-87 292.8 0.3 3.4e-87 292.5 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Hamartin PF04388.12 KKA02710.1 - 2.5 6.7 9.0 2.9 6.4 9.0 1.1 1 0 0 1 1 1 0 Hamartin protein CFEM PF05730.11 KKA02711.1 - 1.6e-07 31.3 11.1 4.1e-07 30.0 11.1 1.7 1 0 0 1 1 1 1 CFEM domain SKA1 PF07160.12 KKA02711.1 - 0.88 9.4 7.5 0.42 10.4 2.0 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 ATP-synt_10 PF05176.14 KKA02712.1 - 3.1e-34 118.4 9.3 1.2e-19 70.6 0.8 2.1 2 0 0 2 2 2 2 ATP10 protein Redoxin PF08534.10 KKA02712.1 - 0.018 14.7 0.0 0.052 13.2 0.0 1.8 1 0 0 1 1 1 0 Redoxin AAA PF00004.29 KKA02713.1 - 1.2e-89 297.6 0.0 4.8e-44 150.0 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA02713.1 - 1.3e-21 76.1 0.1 9.9e-10 38.1 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KKA02713.1 - 4.4e-14 52.5 0.0 1.7e-06 27.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKA02713.1 - 2e-09 38.1 0.3 8.5e-05 23.0 0.0 3.8 2 2 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KKA02713.1 - 7.1e-09 35.8 0.1 0.0033 17.4 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKA02713.1 - 8.3e-09 35.8 0.0 0.0079 16.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKA02713.1 - 9.6e-08 32.4 2.3 0.0011 19.3 0.0 4.7 2 2 3 5 5 5 1 AAA domain TIP49 PF06068.13 KKA02713.1 - 1.2e-07 31.3 0.6 0.012 14.9 0.0 3.1 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 KKA02713.1 - 1.3e-07 31.7 0.0 0.00087 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KKA02713.1 - 8.9e-07 29.0 0.1 0.011 15.7 0.1 3.0 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_33 PF13671.6 KKA02713.1 - 5.4e-06 26.6 0.0 0.22 11.7 0.0 3.0 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 KKA02713.1 - 7.9e-06 26.2 0.0 0.045 14.2 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KKA02713.1 - 1.4e-05 24.6 0.4 0.06 12.7 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 KKA02713.1 - 9.5e-05 22.3 0.0 0.19 11.5 0.0 2.8 2 1 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 KKA02713.1 - 0.00013 22.0 0.0 0.059 13.4 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KKA02713.1 - 0.00023 20.8 0.0 0.41 10.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KKA02713.1 - 0.00038 19.7 0.0 0.018 14.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KKA02713.1 - 0.00048 20.4 0.0 0.8 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KKA02713.1 - 0.00055 19.8 0.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KKA02713.1 - 0.00065 19.6 0.0 0.59 10.0 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KKA02713.1 - 0.00083 19.9 0.0 0.023 15.2 0.0 2.9 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 KKA02713.1 - 0.00098 19.1 0.7 0.016 15.1 0.0 3.2 5 0 0 5 5 3 1 NACHT domain AAA_24 PF13479.6 KKA02713.1 - 0.0037 17.0 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKA02713.1 - 0.0042 16.8 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KKA02713.1 - 0.0053 16.3 0.5 2.2 7.8 0.0 3.8 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.6 KKA02713.1 - 0.0075 16.6 0.1 0.12 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KKA02713.1 - 0.009 15.3 0.0 1.8 7.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 KKA02713.1 - 0.0095 16.0 0.0 2.8 8.1 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_17 PF13207.6 KKA02713.1 - 0.013 16.0 0.5 6.5 7.2 0.1 3.4 4 0 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 KKA02713.1 - 0.013 15.2 0.0 0.37 10.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KKA02713.1 - 0.021 14.6 0.9 0.22 11.2 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 KKA02713.1 - 0.022 15.3 0.0 0.75 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KKA02713.1 - 0.039 13.6 0.0 15 5.2 0.0 3.6 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 KKA02713.1 - 0.044 13.1 0.2 4.1 6.7 0.0 3.1 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 KKA02713.1 - 0.086 12.7 2.0 7.2 6.5 0.0 3.8 3 2 1 4 4 4 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 KKA02713.1 - 0.1 11.5 0.0 0.42 9.4 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.15 KKA02713.1 - 0.15 11.9 0.4 0.9 9.4 0.0 2.5 2 1 1 3 3 2 0 NTPase LemA PF04011.12 KKA02714.1 - 0.032 14.1 0.1 0.092 12.6 0.1 1.7 1 1 0 1 1 1 0 LemA family Bromodomain PF00439.25 KKA02715.1 - 1e-39 134.5 6.9 2.2e-19 69.3 0.4 3.4 4 0 0 4 4 4 2 Bromodomain BET PF17035.5 KKA02715.1 - 0.015 15.5 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation DUF4094 PF13334.6 KKA02715.1 - 3.2 8.2 6.4 2.3 8.7 1.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DSHCT PF08148.12 KKA02716.1 - 2.3e-44 151.0 0.0 6.5e-44 149.5 0.0 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KKA02716.1 - 4.6e-23 81.9 0.2 2e-21 76.6 0.1 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ski2_N PF17911.1 KKA02716.1 - 5.2e-23 81.3 0.1 1.2e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region ResIII PF04851.15 KKA02716.1 - 1.2e-08 35.2 0.1 4.1e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKA02716.1 - 2.5e-06 27.8 0.2 1.7e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C2H2_aberr PF17017.5 KKA02717.1 - 5.2e-05 23.5 13.6 0.02 15.1 0.0 3.5 3 0 0 3 3 3 3 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KKA02717.1 - 0.0011 19.6 16.5 0.08 13.8 1.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKA02717.1 - 0.0016 18.8 21.0 0.025 15.0 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type CDC45 PF02724.14 KKA02717.1 - 0.11 10.8 11.2 0.16 10.3 11.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 KKA02717.1 - 0.82 8.4 8.5 1.4 7.6 8.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 KKA02717.1 - 0.84 8.3 5.3 1.2 7.8 5.3 1.2 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 KKA02717.1 - 1.1 8.6 20.2 2.1 7.7 20.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.22 KKA02717.1 - 1.9 7.6 4.2 2.9 7.0 4.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 KKA02717.1 - 4.3 6.6 16.7 0.18 11.1 11.1 1.5 2 0 0 2 2 2 0 BUD22 zf-H2C2_2 PF13465.6 KKA02717.1 - 5.9 7.5 19.8 0.98 10.0 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double domain RP-C_C PF11800.8 KKA02717.1 - 6 6.9 5.6 13 5.8 5.6 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Roughex PF06020.11 KKA02717.1 - 9.1 5.3 11.1 15 4.6 11.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF1765 PF08578.10 KKA02718.1 - 0.003 18.0 6.6 0.003 18.0 6.6 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF1765) SHNi-TPR PF10516.9 KKA02718.1 - 0.074 12.5 0.1 0.28 10.7 0.1 1.9 1 0 0 1 1 1 0 SHNi-TPR Dus PF01207.17 KKA02719.1 - 7.3e-60 202.7 0.0 9.4e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Mnd1 PF03962.15 KKA02719.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Mnd1 HTH domain Ribosomal_L31e PF01198.19 KKA02720.1 - 1.1e-40 137.8 1.6 1.3e-40 137.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rxt3 PF08642.10 KKA02721.1 - 7.8e-09 36.4 0.0 2.5e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 DUF4050 PF13259.6 KKA02722.1 - 1.4e-05 25.5 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) RRM_1 PF00076.22 KKA02723.1 - 2.5e-14 52.8 4.6 2.9e-06 27.0 0.3 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5-FTHF_cyc-lig PF01812.20 KKA02723.1 - 0.0052 16.6 0.2 0.0098 15.7 0.2 1.4 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ACT_7 PF13840.6 KKA02723.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 ACT domain Glucosamine_iso PF01182.20 KKA02724.1 - 1.7e-55 188.4 0.0 1.9e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aminotran_5 PF00266.19 KKA02725.1 - 8.7e-95 317.8 0.0 1.1e-94 317.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKA02725.1 - 9.1e-07 28.5 0.0 4.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKA02725.1 - 1e-06 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KKA02725.1 - 0.044 12.5 0.2 0.073 11.8 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Iso_dh PF00180.20 KKA02726.1 - 1e-122 409.6 0.0 1.2e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD PF12710.7 KKA02727.1 - 8.7e-20 71.9 0.0 1.1e-19 71.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKA02727.1 - 9.6e-08 31.7 0.8 1.2e-07 31.4 0.8 1.1 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 KKA02727.1 - 0.00083 19.7 0.0 0.14 12.4 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKA02727.1 - 0.0035 17.4 0.2 0.049 13.7 0.1 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KKA02727.1 - 0.048 13.2 0.0 0.092 12.2 0.0 1.7 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) SIS PF01380.22 KKA02727.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 SIS domain HTH_52 PF18576.1 KKA02727.1 - 0.11 12.8 1.1 2.9 8.2 0.0 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain EF-hand_6 PF13405.6 KKA02728.1 - 1.2e-05 24.8 4.7 0.0022 17.8 0.8 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KKA02728.1 - 1.5e-05 25.4 3.5 1.5e-05 25.4 3.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KKA02728.1 - 0.00017 20.9 4.1 0.0045 16.4 1.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KKA02728.1 - 0.034 14.0 1.7 0.1 12.5 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain pair ABC_tran PF00005.27 KKA02729.1 - 2.5e-45 154.4 0.1 1e-22 81.1 0.0 4.2 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KKA02729.1 - 1.8e-29 101.6 0.5 7.1e-29 99.7 0.5 2.2 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 KKA02729.1 - 3.9e-17 63.0 1.1 0.0071 16.2 0.0 4.7 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKA02729.1 - 9.1e-16 58.0 0.1 3.6e-06 26.6 0.1 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKA02729.1 - 1.5e-08 35.4 6.1 0.0011 19.5 0.1 3.3 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.6 KKA02729.1 - 1.6e-08 34.2 0.0 0.0072 16.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KKA02729.1 - 1.7e-08 34.9 0.1 0.0095 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKA02729.1 - 2.4e-08 34.0 0.0 0.00093 19.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KKA02729.1 - 2.6e-08 34.2 0.0 0.0018 18.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 KKA02729.1 - 4.7e-08 33.1 0.0 0.0024 17.9 0.0 3.4 3 0 0 3 3 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KKA02729.1 - 4.7e-08 33.3 0.0 1.3e-05 25.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 KKA02729.1 - 1.8e-06 28.4 0.0 0.085 13.3 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KKA02729.1 - 2.6e-06 27.8 0.0 0.12 12.8 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KKA02729.1 - 2.4e-05 24.9 0.2 0.52 10.8 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.6 KKA02729.1 - 3.5e-05 24.0 0.0 0.45 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KKA02729.1 - 4e-05 23.5 0.0 0.32 10.6 0.1 3.2 3 0 0 3 3 2 2 AAA ATPase domain MeaB PF03308.16 KKA02729.1 - 4.7e-05 22.5 0.3 0.24 10.4 0.0 2.7 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KKA02729.1 - 5.3e-05 23.0 0.0 0.2 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KKA02729.1 - 8.6e-05 23.0 0.1 0.18 12.1 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 KKA02729.1 - 0.00018 21.3 0.1 0.3 10.8 0.0 3.9 3 1 1 4 4 3 1 Ethanolamine utilisation - propanediol utilisation MMS19_C PF12460.8 KKA02729.1 - 0.00022 20.5 3.1 0.031 13.4 0.2 2.7 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal AAA_27 PF13514.6 KKA02729.1 - 0.00027 20.6 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KKA02729.1 - 0.00046 20.2 0.0 0.95 9.3 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 KKA02729.1 - 0.00067 19.8 0.6 0.45 10.6 0.0 3.8 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_14 PF13173.6 KKA02729.1 - 0.0015 18.6 0.0 2.3 8.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KKA02729.1 - 0.0016 18.2 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KKA02729.1 - 0.002 18.1 0.0 1.2 9.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain SbcCD_C PF13558.6 KKA02729.1 - 0.002 18.3 0.0 0.79 10.0 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CLP1_P PF16575.5 KKA02729.1 - 0.0024 17.7 0.2 1.1 9.1 0.0 3.7 4 0 0 4 4 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 KKA02729.1 - 0.0066 16.1 0.0 4.3 6.9 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KKA02729.1 - 0.0079 15.7 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CLASP_N PF12348.8 KKA02729.1 - 0.0099 15.5 0.7 0.12 11.9 0.6 2.5 1 1 1 2 2 2 1 CLASP N terminal AAA_13 PF13166.6 KKA02729.1 - 0.011 14.5 2.7 3.1 6.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 KKA02729.1 - 0.011 15.9 0.0 6.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KKA02729.1 - 0.013 15.4 0.8 6.9 6.5 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KKA02729.1 - 0.014 15.3 0.1 7 6.5 0.0 2.9 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 KKA02729.1 - 0.014 15.1 0.0 4.1 7.1 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ParcG PF10274.9 KKA02729.1 - 0.014 15.5 0.2 2.1 8.4 0.1 3.0 1 1 1 3 3 3 0 Parkin co-regulated protein Cytidylate_kin PF02224.18 KKA02729.1 - 0.019 14.7 0.0 6 6.5 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 KKA02729.1 - 0.023 14.1 0.1 2.6 7.4 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KKA02729.1 - 0.024 13.9 0.2 13 5.0 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin T2SSE PF00437.20 KKA02729.1 - 0.024 13.7 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KKA02729.1 - 0.032 14.0 0.1 7.6 6.2 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KKA02729.1 - 0.033 13.5 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 KKA02729.1 - 0.059 12.5 0.1 4 6.5 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 KKA02729.1 - 0.083 12.1 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KKA02729.1 - 0.088 12.8 0.1 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 KKA02729.1 - 0.093 12.6 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MutS_V PF00488.21 KKA02729.1 - 0.094 12.7 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 MutS domain V DUF3855 PF12967.7 KKA02729.1 - 0.098 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) FeoB_N PF02421.18 KKA02729.1 - 0.11 12.0 0.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MukB PF04310.12 KKA02729.1 - 0.14 12.0 0.5 15 5.3 0.0 2.7 3 0 0 3 3 2 0 MukB N-terminal HEAT_EZ PF13513.6 KKA02729.1 - 1.1 9.8 3.4 2e+02 2.6 0.0 4.6 3 1 2 5 5 4 0 HEAT-like repeat Adaptin_N PF01602.20 KKA02729.1 - 2.2 6.8 6.5 1.6 7.2 3.9 2.0 2 1 0 2 2 1 0 Adaptin N terminal region Pkinase PF00069.25 KKA02730.1 - 3.1e-52 177.6 0.0 4.2e-48 164.0 0.0 3.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02730.1 - 2.4e-20 72.9 0.0 2.3e-16 59.9 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKA02730.1 - 0.0039 16.5 0.0 0.49 9.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KKA02730.1 - 0.0093 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.23 KKA02731.1 - 4.9e-31 107.7 1.8 1.1e-30 106.6 1.8 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KKA02731.1 - 2e-09 37.7 9.6 3.7e-09 36.8 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKA02731.1 - 2.1e-09 37.1 8.8 4.2e-09 36.1 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKA02731.1 - 2.7e-09 36.7 8.4 5.8e-09 35.6 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKA02731.1 - 3.4e-08 33.2 10.0 5.5e-08 32.5 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KKA02731.1 - 5.1e-06 26.8 1.2 2.2e-05 24.7 0.2 2.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KKA02731.1 - 1.2e-05 25.2 5.9 2.8e-05 24.1 5.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KKA02731.1 - 1.3e-05 25.2 11.1 2.8e-05 24.2 11.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KKA02731.1 - 5.5e-05 23.4 5.5 0.00013 22.1 5.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KKA02731.1 - 0.0026 17.6 10.2 0.005 16.7 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKA02731.1 - 0.0038 17.2 8.5 0.007 16.3 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.14 KKA02731.1 - 0.05 13.3 9.2 0.14 11.8 9.2 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KKA02731.1 - 0.054 13.5 3.8 0.14 12.2 3.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KKA02731.1 - 0.19 11.5 5.0 0.6 9.9 5.0 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 KKA02731.1 - 0.46 10.6 6.4 1.4 9.1 6.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KKA02731.1 - 2.6 7.9 9.1 5.6 6.9 9.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Abhydrolase_6 PF12697.7 KKA02732.1 - 1.5e-10 42.0 0.0 2.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKA02732.1 - 2.8e-09 37.0 0.0 6.8e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA02732.1 - 9.8e-05 21.7 0.0 0.00019 20.8 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KKA02732.1 - 0.015 14.9 0.0 1.2 8.8 0.0 2.8 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKA02732.1 - 0.043 13.6 0.5 0.61 9.9 0.1 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF2847 PF11009.8 KKA02733.1 - 0.05 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) WD40 PF00400.32 KKA02734.1 - 0.00013 22.6 0.3 1.6 9.7 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF5352 PF17303.2 KKA02734.1 - 0.0065 16.3 0.5 0.018 14.9 0.5 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5352) ANAPC4_WD40 PF12894.7 KKA02734.1 - 0.0092 16.3 0.1 8.8 6.7 0.0 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KKA02734.1 - 0.03 13.9 0.7 0.73 9.4 0.1 2.4 2 0 0 2 2 2 0 CNH domain TP_methylase PF00590.20 KKA02735.1 - 1.1e-21 77.7 0.0 2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Clat_adaptor_s PF01217.20 KKA02736.1 - 1.8e-42 144.7 3.2 4e-42 143.5 3.2 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Fur_reg_FbpB PF13040.6 KKA02736.1 - 0.0035 16.8 1.5 0.0089 15.6 1.5 1.6 1 0 0 1 1 1 1 Fur-regulated basic protein B MRG PF05712.13 KKA02736.1 - 0.01 15.2 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 0 MRG RhoGAP PF00620.27 KKA02737.1 - 4.4e-30 104.5 0.1 1.5e-29 102.8 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KKA02737.1 - 0.021 15.1 3.2 0.13 12.6 3.2 2.3 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF948 PF06103.11 KKA02737.1 - 0.051 13.8 2.5 2.4 8.5 0.4 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 KKA02737.1 - 0.64 10.3 2.9 2.4 8.4 2.5 2.2 2 0 0 2 2 2 0 Haemolysin XhlA P4Ha_N PF08336.11 KKA02737.1 - 2 8.4 7.7 1.8 8.6 2.4 3.0 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PI3_PI4_kinase PF00454.27 KKA02738.1 - 2.2e-12 47.4 2.2 2.9e-11 43.7 2.2 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GCS PF03074.16 KKA02739.1 - 2.6e-123 412.0 0.8 3.4e-123 411.6 0.8 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KKA02739.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) GTP_EFTU PF00009.27 KKA02740.1 - 4.2e-57 192.8 0.3 9e-57 191.8 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKA02740.1 - 1.3e-11 44.3 0.0 2.9e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 KKA02740.1 - 1e-09 38.3 0.0 3.1e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KKA02740.1 - 0.0049 16.9 2.5 0.015 15.4 0.7 2.7 2 1 0 3 3 3 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKA02740.1 - 0.029 13.8 0.3 0.13 11.6 0.3 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 KKA02740.1 - 0.033 13.5 0.9 0.23 10.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family POLO_box PF00659.18 KKA02740.1 - 0.11 12.7 0.8 1.6 9.0 0.3 2.9 2 0 0 2 2 2 0 POLO box duplicated region Ribosomal_L4 PF00573.22 KKA02741.1 - 4.5e-41 140.7 2.0 8.6e-41 139.7 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KKA02741.1 - 3.2e-30 104.0 4.2 3.9e-29 100.5 1.0 2.7 3 0 0 3 3 3 2 60S ribosomal protein L4 C-terminal domain Snf7 PF03357.21 KKA02742.1 - 0.09 12.4 17.6 0.13 11.9 17.6 1.4 1 0 0 1 1 1 0 Snf7 DUF4320 PF14208.6 KKA02742.1 - 0.099 12.7 3.4 0.23 11.6 3.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4320) HD_2 PF12917.7 KKA02742.1 - 0.2 11.4 4.8 0.043 13.6 1.6 1.5 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme Cpn60_TCP1 PF00118.24 KKA02743.1 - 3.9e-146 487.5 9.4 4.5e-146 487.3 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family OsmC PF02566.19 KKA02743.1 - 0.15 12.6 0.4 1.2 9.6 0.1 2.5 3 0 0 3 3 3 0 OsmC-like protein Mod_r PF07200.13 KKA02743.1 - 0.94 9.6 4.6 2.4 8.3 1.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MAM33 PF02330.16 KKA02744.1 - 1.3e-07 31.8 4.4 2.1e-07 31.1 4.4 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein WD40 PF00400.32 KKA02745.1 - 3.1e-16 59.4 5.4 8.7e-06 26.4 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA02745.1 - 1.4e-06 28.5 0.6 0.31 11.4 0.0 4.9 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKA02745.1 - 2.6e-05 23.1 2.7 0.027 13.2 0.3 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KKA02745.1 - 4.2e-05 23.0 3.6 0.045 13.1 0.2 3.2 2 1 1 3 3 3 3 WD40-like domain DAP_B PF07930.12 KKA02746.1 - 0.14 12.1 1.3 0.53 10.2 1.1 1.8 1 1 1 2 2 2 0 D-aminopeptidase, domain B Ribosomal_L7Ae PF01248.26 KKA02747.1 - 4e-22 77.8 0.4 5.1e-22 77.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rad1 PF02144.16 KKA02748.1 - 2.9e-14 52.8 4.2 5e-14 52.0 4.2 1.4 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 TRP PF06011.12 KKA02749.1 - 3.8e-137 457.5 43.0 5.1e-137 457.1 43.0 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKA02749.1 - 1.7e-37 128.9 4.7 3.5e-37 127.8 4.7 1.6 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KKA02749.1 - 0.0085 16.5 0.3 0.016 15.6 0.3 1.4 1 0 0 1 1 1 1 ML domain Aerolysin PF01117.20 KKA02750.1 - 0.069 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Aerolysin toxin Glyco_transf_9 PF01075.17 KKA02750.1 - 0.071 12.4 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Cupin_8 PF13621.6 KKA02751.1 - 2.5e-10 40.5 0.4 6.3e-10 39.2 0.4 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KKA02751.1 - 7.8e-07 29.5 4.4 1e-06 29.2 0.2 3.2 3 1 0 3 3 3 1 JmjC domain, hydroxylase Elongin_A PF06881.11 KKA02751.1 - 0.011 16.2 0.7 0.011 16.2 0.7 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GPI PF06560.11 KKA02751.1 - 0.13 11.5 0.2 0.25 10.6 0.2 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 KKA02751.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ribosomal_L32p PF01783.23 KKA02752.1 - 2.9e-13 49.9 0.6 6.2e-13 48.8 0.6 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family TerY_C PF15616.6 KKA02752.1 - 0.045 13.9 1.1 3.9 7.6 0.0 2.1 1 1 1 2 2 2 0 TerY-C metal binding domain DUF4428 PF14471.6 KKA02752.1 - 0.6 10.1 4.8 3.4 7.7 4.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Hydrolase_like PF13242.6 KKA02753.1 - 2.3e-23 82.0 0.0 4.5e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KKA02753.1 - 5.9e-20 71.3 0.0 1.3e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKA02753.1 - 0.00016 22.0 0.0 0.0072 16.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKA02753.1 - 0.00023 21.3 0.1 0.0078 16.3 0.1 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PsbR PF04725.12 KKA02753.1 - 0.023 15.0 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR eRF1_2 PF03464.15 KKA02754.1 - 2.7e-25 89.2 0.3 4.7e-25 88.4 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KKA02754.1 - 6.4e-23 81.4 0.6 1.7e-22 80.0 0.0 2.1 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_1 PF03463.15 KKA02754.1 - 5.1e-15 55.6 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 Rer1 PF03248.13 KKA02755.1 - 7.6e-70 234.1 11.4 8.8e-70 233.9 11.4 1.0 1 0 0 1 1 1 1 Rer1 family DUF2207 PF09972.9 KKA02755.1 - 6.6 5.4 9.3 1.1e+02 1.3 9.2 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PQ-loop PF04193.14 KKA02756.1 - 0.00093 18.9 1.5 0.00093 18.9 1.5 3.2 4 0 0 4 4 4 1 PQ loop repeat Tmemb_14 PF03647.13 KKA02756.1 - 2.1 9.1 5.1 6.3 7.6 2.1 2.8 2 1 0 2 2 2 0 Transmembrane proteins 14C PLDc_2 PF13091.6 KKA02757.1 - 1.8e-17 63.5 0.1 2.1e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KKA02757.1 - 2.9e-07 30.4 3.8 0.0027 17.8 0.1 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif Ribosomal_L30 PF00327.20 KKA02758.1 - 4.2e-11 42.6 2.0 1.4e-10 40.8 0.5 2.5 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 KKA02758.1 - 0.052 13.8 17.8 0.17 12.1 17.8 1.9 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain MAS20 PF02064.15 KKA02758.1 - 9.5 6.3 11.1 2.2 8.4 7.8 1.6 2 0 0 2 2 2 0 MAS20 protein import receptor WD40 PF00400.32 KKA02759.1 - 1.7e-45 152.1 20.4 1.7e-10 41.3 0.3 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA02759.1 - 1.4e-14 54.1 5.0 0.002 18.4 0.1 5.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKA02759.1 - 9.1e-08 31.4 1.4 0.35 9.8 0.1 4.0 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KKA02759.1 - 1.4e-07 30.6 4.6 4.3e-05 22.4 0.3 3.7 1 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 KKA02759.1 - 3e-07 29.5 5.5 0.0065 15.2 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KKA02759.1 - 1.8e-05 23.8 5.4 8e-05 21.7 0.1 3.4 4 1 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 KKA02759.1 - 0.00078 19.2 1.6 1 9.1 0.1 4.0 1 1 1 3 3 3 2 TUP1-like enhancer of split Frtz PF11768.8 KKA02759.1 - 0.0042 15.5 0.0 0.012 13.9 0.0 1.7 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KKA02759.1 - 0.051 12.1 0.4 4.5 5.7 0.2 2.8 1 1 0 2 2 2 0 Cytochrome D1 heme domain Utp8 PF10395.9 KKA02759.1 - 0.068 11.7 0.1 5 5.5 0.1 2.6 2 1 1 3 3 3 0 Utp8 family DnaJ_C PF01556.18 KKA02760.1 - 2.3e-31 108.9 1.1 2.9e-31 108.6 1.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKA02760.1 - 5.9e-22 77.6 0.4 5.9e-22 77.6 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain DKCLD PF08068.12 KKA02761.1 - 4.6e-32 109.9 0.2 7.7e-31 106.0 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KKA02761.1 - 2.6e-22 78.7 0.4 5.7e-22 77.6 0.4 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KKA02761.1 - 7.3e-22 78.3 4.1 1.9e-20 73.7 0.0 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KKA02761.1 - 2e-21 75.7 1.2 4e-21 74.8 1.2 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KKA02761.1 - 0.0016 18.6 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain RR_TM4-6 PF06459.12 KKA02761.1 - 0.19 11.5 16.0 0.25 11.1 16.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SmAKAP PF15127.6 KKA02762.1 - 0.085 14.1 1.1 0.43 11.8 0.0 2.4 2 1 0 2 2 2 0 Small membrane A-kinase anchor protein Arrestin_C PF02752.22 KKA02763.1 - 5.1e-16 59.3 0.1 2e-15 57.4 0.1 2.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKA02763.1 - 2.5e-11 43.8 0.0 2.4e-07 30.9 0.0 2.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Mpv17_PMP22 PF04117.12 KKA02764.1 - 3.4e-21 75.2 3.2 7.9e-21 74.0 3.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.18 KKA02765.1 - 4.6e-05 23.5 9.6 8e-05 22.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1776 PF08643.10 KKA02766.1 - 1.8e-11 44.0 6.0 2.4e-08 33.7 0.0 2.9 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Lipase_GDSL_3 PF14606.6 KKA02766.1 - 0.021 14.9 1.1 0.074 13.2 1.1 1.9 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ProRS-C_1 PF09180.11 KKA02767.1 - 2.3e-26 91.8 1.5 5.2e-26 90.7 1.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KKA02767.1 - 9.6e-18 64.1 0.1 2e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKA02767.1 - 1.7e-12 47.6 0.0 3.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 KKA02767.1 - 0.004 17.2 0.1 0.0078 16.3 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain PHP PF02811.19 KKA02768.1 - 3.2e-09 37.3 4.7 3.2e-09 37.3 4.7 1.8 2 1 0 2 2 2 1 PHP domain DAO PF01266.24 KKA02769.1 - 5.8e-17 62.3 0.0 5.6e-16 59.1 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKA02769.1 - 0.017 14.4 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DUF150_C PF17384.2 KKA02770.1 - 0.02 15.0 0.1 0.071 13.3 0.1 2.0 1 0 0 1 1 1 0 RimP C-terminal SH3 domain LSM PF01423.22 KKA02770.1 - 0.081 12.6 0.1 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 LSM domain Arm PF00514.23 KKA02771.1 - 3.7e-61 201.4 16.0 3.2e-09 36.5 0.0 10.9 10 1 1 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKA02771.1 - 9.5e-17 61.1 6.2 0.00089 19.7 0.1 7.0 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KKA02771.1 - 7.3e-13 48.7 4.0 8.6e-05 22.8 0.0 6.8 4 2 3 8 8 8 4 HEAT repeats HEAT PF02985.22 KKA02771.1 - 6.3e-11 41.6 15.4 0.049 13.9 0.3 9.0 10 0 0 10 10 9 3 HEAT repeat Adaptin_N PF01602.20 KKA02771.1 - 5.2e-10 38.5 9.5 9.3e-06 24.5 2.7 2.4 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KKA02771.1 - 2.4e-09 35.9 2.8 7.5e-09 34.3 2.6 1.9 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 KKA02771.1 - 4.9e-06 26.2 7.1 0.00074 19.0 0.8 2.4 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 KKA02771.1 - 0.00042 19.7 1.0 0.0045 16.3 0.4 2.6 1 1 0 1 1 1 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 KKA02771.1 - 0.00065 20.2 1.1 9.4 6.9 0.0 4.5 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KKA02771.1 - 0.011 16.3 4.9 0.72 10.7 0.1 5.4 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat RIF5_SNase_1 PF18187.1 KKA02771.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 V-ATPase_H_C PF11698.8 KKA02771.1 - 0.012 15.7 11.0 1.9 8.6 0.3 4.9 3 1 3 6 6 6 0 V-ATPase subunit H UNC45-central PF11701.8 KKA02771.1 - 0.026 14.5 8.9 11 5.9 0.0 4.6 4 2 1 5 5 5 0 Myosin-binding striated muscle assembly central Zn_clus PF00172.18 KKA02772.1 - 2.3e-07 30.8 8.4 5.2e-07 29.7 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S16 PF00886.19 KKA02774.1 - 2.4e-12 46.7 0.0 4.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 zf-Nse PF11789.8 KKA02775.1 - 1.3e-09 37.7 0.1 2.7e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKA02775.1 - 9.7e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger tRNA-synt_2 PF00152.20 KKA02776.1 - 5.2e-78 262.3 1.6 8.1e-78 261.7 1.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KKA02776.1 - 7.3e-05 22.4 0.7 0.25 10.8 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KKA02776.1 - 0.00032 20.6 0.3 0.0023 17.9 0.1 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain OMPdecase PF00215.24 KKA02777.1 - 1.8e-77 259.9 0.0 2.1e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2508 PF10704.9 KKA02777.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Sec7 PF01369.20 KKA02778.1 - 2.4e-61 206.6 3.9 2.4e-61 206.6 3.9 2.8 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 KKA02778.1 - 9e-08 32.2 8.1 9e-08 32.2 8.1 4.1 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pro_isomerase PF00160.21 KKA02779.1 - 1.2e-36 126.4 0.5 1.8e-36 125.8 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KKA02779.1 - 0.0003 20.7 7.2 2.5 8.4 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKA02779.1 - 0.0046 17.1 0.7 2.1 8.8 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKA02779.1 - 0.2 11.5 12.8 0.31 11.0 0.8 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KKA02779.1 - 0.85 9.7 5.8 14 5.8 0.2 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KKA02779.1 - 3.8 7.7 7.8 5.9 7.1 0.4 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Rav1p_C PF12234.8 KKA02780.1 - 2e-22 79.4 0.6 2e-22 79.4 0.6 2.0 2 0 0 2 2 2 1 RAVE protein 1 C terminal Ribosomal_L27 PF01016.19 KKA02781.1 - 6.5e-23 80.6 0.6 1.1e-22 79.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein ALS_ss_C PF10369.9 KKA02782.1 - 4.7e-17 62.0 0.0 2.7e-16 59.5 0.0 2.3 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KKA02782.1 - 5.1e-12 45.3 1.6 6.8e-12 44.9 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 KKA02782.1 - 1.5e-08 34.4 0.2 5e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 ACT domain Limkain-b1 PF11608.8 KKA02782.1 - 0.024 14.7 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 E1-E2_ATPase PF00122.20 KKA02783.1 - 0.31 10.6 2.1 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 E1-E2 ATPase Cadherin_C_2 PF16492.5 KKA02784.1 - 0.17 12.6 1.8 0.36 11.6 1.8 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal tRNA-synt_2 PF00152.20 KKA02785.1 - 1.7e-88 296.8 0.0 2.3e-88 296.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKA02785.1 - 1e-12 47.9 0.0 2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3283 PF11686.8 KKA02785.1 - 0.05 13.5 1.0 0.17 11.7 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) Lyase_1 PF00206.20 KKA02786.1 - 1.2e-102 343.5 0.0 8.6e-102 340.7 0.0 2.0 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KKA02786.1 - 4.9e-22 78.5 0.0 1.2e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Zn_clus PF00172.18 KKA02787.1 - 4.7e-06 26.6 15.4 9.3e-06 25.7 15.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KKA02787.1 - 0.075 12.9 4.6 0.19 11.7 4.6 1.7 1 0 0 1 1 1 0 AT hook motif DIRP PF06584.13 KKA02787.1 - 0.095 12.9 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 DIRP Ysc84 PF04366.12 KKA02788.1 - 5.8e-38 129.5 0.1 9.3e-38 128.9 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KKA02788.1 - 1.5e-14 53.3 0.3 3.3e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKA02788.1 - 9.2e-13 47.7 0.0 1.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKA02788.1 - 4.7e-12 45.6 0.0 8.4e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PGK PF00162.19 KKA02789.1 - 1.4e-146 488.3 0.4 1.6e-146 488.1 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 KKA02789.1 - 0.13 11.8 0.2 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Propionate catabolism activator Pox_E10 PF04805.12 KKA02790.1 - 0.023 14.5 0.2 0.085 12.7 0.2 2.0 1 0 0 1 1 1 0 E10-like protein conserved region UCH PF00443.29 KKA02791.1 - 2.8e-52 177.8 8.1 2.8e-52 177.8 8.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKA02791.1 - 8.5e-18 65.0 13.5 8.5e-18 65.0 13.5 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Reprolysin_3 PF13582.6 KKA02791.1 - 0.098 13.2 1.9 0.32 11.5 0.1 2.9 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_C28 PF05408.11 KKA02791.1 - 0.17 11.6 1.7 0.55 9.9 0.2 2.3 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase Cytochrom_B562 PF07361.11 KKA02791.1 - 1.5 9.5 5.5 4.3 8.0 0.1 3.4 3 1 0 3 3 3 0 Cytochrome b562 ABC2_membrane PF01061.24 KKA02792.1 - 2.8e-61 206.6 41.4 2.7e-38 131.5 14.3 3.0 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KKA02792.1 - 1.1e-35 121.4 1.0 1.1e-29 102.2 0.2 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KKA02792.1 - 4.1e-17 63.0 1.8 5.3e-17 62.6 0.1 2.1 3 0 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 KKA02792.1 - 7e-06 25.7 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KKA02792.1 - 4.6e-05 23.0 0.0 0.024 14.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKA02792.1 - 0.0001 22.2 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KKA02792.1 - 0.00013 22.4 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KKA02792.1 - 0.00026 20.9 0.0 0.22 11.3 0.1 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KKA02792.1 - 0.00086 18.5 33.0 0.0086 15.2 10.8 3.5 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_29 PF13555.6 KKA02792.1 - 0.0011 18.6 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KKA02792.1 - 0.014 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKA02792.1 - 0.014 16.0 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKA02792.1 - 0.015 15.8 1.5 0.029 14.9 0.5 2.0 2 1 0 2 2 1 0 AAA domain PDR_assoc PF08370.11 KKA02792.1 - 0.025 14.3 0.2 0.025 14.3 0.2 4.4 6 0 0 6 6 4 0 Plant PDR ABC transporter associated Zip PF02535.22 KKA02792.1 - 0.038 13.2 1.7 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter AAA_22 PF13401.6 KKA02792.1 - 0.12 12.6 0.9 0.23 11.8 0.3 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KKA02792.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 KKA02792.1 - 0.17 11.4 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Atg8 PF02991.16 KKA02793.1 - 2.3e-38 130.5 0.5 1.9e-36 124.4 0.5 2.1 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KKA02793.1 - 2.2e-09 37.6 0.0 3.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 KKA02793.1 - 0.073 12.7 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 Nucleoporin_N PF08801.11 KKA02794.1 - 2.8e-64 217.5 14.3 4.4e-64 216.8 14.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KKA02794.1 - 4.9e-39 134.5 33.8 1.4e-38 133.1 28.5 3.2 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal XPG_I PF00867.18 KKA02796.1 - 1.2e-21 76.9 0.1 5.7e-21 74.7 0.1 2.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KKA02796.1 - 1.1e-17 64.3 0.0 7.8e-17 61.6 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 KKA02796.1 - 0.0048 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing GatB_N PF02934.15 KKA02797.1 - 8.1e-83 278.0 0.0 1.1e-82 277.6 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain Acetyltransf_4 PF13420.7 KKA02797.1 - 1.6 8.8 5.8 2.5 8.2 0.0 3.5 3 1 1 4 4 4 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 KKA02799.1 - 1.1e-15 57.7 6.7 0.00052 20.8 0.4 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA02799.1 - 0.0018 18.5 0.0 4.8 7.5 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKA02799.1 - 0.01 14.9 0.0 1.4 7.8 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CAML PF14963.6 KKA02800.1 - 0.01 16.0 1.2 0.01 16.0 1.2 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand LisH PF08513.11 KKA02800.1 - 0.034 14.1 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 LisH ALG3 PF05208.13 KKA02801.1 - 9.4e-104 347.7 23.2 1.2e-103 347.4 23.2 1.1 1 0 0 1 1 1 1 ALG3 protein HEAT_EZ PF13513.6 KKA02802.1 - 1.6e-10 41.2 0.0 0.013 16.0 0.0 6.9 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 KKA02802.1 - 1.2e-09 37.5 0.8 0.8 10.1 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat IBN_N PF03810.19 KKA02802.1 - 4.4e-08 32.9 5.2 1.8e-07 31.0 0.4 4.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KKA02802.1 - 2.8e-06 27.6 0.0 5 7.6 0.1 5.6 3 2 4 7 7 7 2 HEAT repeats Ipi1_N PF12333.8 KKA02802.1 - 0.00037 21.0 0.1 20 5.9 0.0 4.5 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 KKA02802.1 - 0.0021 18.6 5.8 7.3 7.3 0.2 5.8 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KKA02802.1 - 0.02 14.8 6.8 10 6.0 0.0 5.8 4 3 1 6 6 6 0 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 KKA02802.1 - 0.12 12.6 0.4 0.87 9.8 0.1 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ank_4 PF13637.6 KKA02803.1 - 3.3e-10 40.3 0.3 1.9e-05 25.1 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKA02803.1 - 3.5e-10 40.3 0.2 1.4e-05 25.6 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKA02803.1 - 1.7e-08 34.5 0.1 0.00064 20.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA02803.1 - 2.9e-08 33.3 0.1 0.00049 20.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KKA02803.1 - 1e-07 32.1 0.1 0.015 15.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Adaptin_N PF01602.20 KKA02804.1 - 3.5e-47 161.2 23.8 3.7e-46 157.8 23.8 2.5 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KKA02804.1 - 2.1e-11 44.1 1.8 7.7e-11 42.3 1.8 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 KKA02804.1 - 0.0027 16.9 8.3 0.12 11.6 1.0 3.8 4 1 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain Vps39_1 PF10366.9 KKA02804.1 - 1.4 9.2 6.1 1.8 8.9 0.2 4.1 2 2 3 5 5 5 0 Vacuolar sorting protein 39 domain 1 Glyco_hydro_65m PF03632.15 KKA02805.1 - 9.3e-36 123.5 4.9 1e-32 113.5 0.2 3.4 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KKA02805.1 - 1.6e-12 47.6 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain ATP-synt_ab PF00006.25 KKA02806.1 - 2.3e-71 239.9 0.0 5e-71 238.7 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KKA02806.1 - 1.4e-45 154.7 1.6 2.3e-45 154.0 1.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KKA02806.1 - 7e-17 61.7 3.4 9.5e-17 61.3 1.6 2.2 1 1 1 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HTH_IclR PF09339.10 KKA02806.1 - 0.1 12.4 0.6 0.54 10.1 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain Cyclin_C_2 PF16899.5 KKA02807.1 - 2.7e-21 75.9 0.6 3.7e-20 72.2 0.1 2.5 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KKA02807.1 - 3.5e-10 39.7 0.8 7.8e-10 38.6 0.8 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KKA02807.1 - 8.6e-06 25.7 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Peptidase_M41 PF01434.18 KKA02808.1 - 2.6e-59 200.3 0.1 5.1e-59 199.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KKA02808.1 - 1.2e-41 142.2 0.2 4.8e-41 140.3 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA02808.1 - 8.8e-10 38.2 0.0 2.3e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKA02808.1 - 1.8e-05 25.2 0.2 0.00012 22.5 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKA02808.1 - 0.00012 22.4 0.1 0.063 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KKA02808.1 - 0.00019 20.7 0.0 0.0004 19.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KKA02808.1 - 0.00061 19.8 0.1 0.0036 17.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKA02808.1 - 0.0019 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KKA02808.1 - 0.012 15.0 0.5 0.025 14.0 0.5 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKA02808.1 - 0.013 15.2 0.1 0.035 13.8 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein SpoU_sub_bind PF08032.12 KKA02808.1 - 0.019 15.3 0.1 15 6.0 0.3 3.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding AAA_18 PF13238.6 KKA02808.1 - 0.027 15.0 0.2 0.16 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKA02808.1 - 0.028 14.0 2.7 0.35 10.4 0.4 2.7 2 1 0 3 3 3 0 AAA domain DNA_ligase_C PF17879.1 KKA02808.1 - 0.031 14.3 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 DNA ligase C-terminal domain TsaE PF02367.17 KKA02808.1 - 0.031 14.3 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KKA02808.1 - 0.04 14.1 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKA02808.1 - 0.053 13.6 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KKA02808.1 - 0.055 13.6 0.0 0.22 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 KKA02808.1 - 0.094 12.0 0.8 1 8.6 0.0 2.7 3 0 0 3 3 3 0 KaiC Cnd2 PF05786.14 KKA02809.1 - 6.3e-123 412.1 41.8 8.4e-123 411.6 41.8 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF2433 PF10360.9 KKA02809.1 - 0.049 13.7 3.1 0.082 13.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) ArfGap PF01412.18 KKA02811.1 - 2.1e-31 108.4 1.5 2.1e-31 108.4 1.5 2.6 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DUF3973 PF13119.6 KKA02811.1 - 0.063 13.4 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) zf-CRD PF17979.1 KKA02811.1 - 0.11 12.6 1.4 15 5.7 0.0 2.8 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Rox3 PF08633.10 KKA02812.1 - 4.1e-18 66.4 0.1 5.4e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.18 KKA02813.1 - 2.4e-46 156.6 1.6 2.9e-46 156.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Kelch_4 PF13418.6 KKA02814.1 - 9.1e-05 22.4 0.5 0.022 14.7 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 KKA02814.1 - 0.068 13.5 2.9 11 6.5 0.1 4.3 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.6 KKA02814.1 - 0.3 11.1 9.2 2.7 8.1 0.1 4.7 5 0 0 5 5 5 0 Kelch motif zf-C2H2 PF00096.26 KKA02816.1 - 9.5e-10 38.4 17.8 4.1e-05 23.8 4.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKA02816.1 - 2.4e-07 31.0 13.5 0.00058 20.5 2.6 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKA02816.1 - 5.2e-07 29.8 0.9 5.2e-07 29.8 0.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_2 PF12756.7 KKA02816.1 - 0.005 17.1 4.2 0.23 11.8 0.1 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 KKA02816.1 - 0.011 15.7 1.6 0.12 12.4 0.1 2.2 1 1 1 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.6 KKA02816.1 - 0.02 14.9 9.5 0.036 14.1 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKA02816.1 - 0.023 15.0 7.0 0.59 10.5 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KKA02816.1 - 0.029 14.3 7.9 0.14 12.1 2.4 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-FCS PF06467.14 KKA02816.1 - 0.076 13.0 6.0 1.5 8.8 0.3 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_12 PF11331.8 KKA02816.1 - 0.19 11.6 0.9 0.33 10.8 0.9 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-C2HE PF16278.5 KKA02816.1 - 0.19 12.2 7.8 2.1 8.9 1.3 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 KKA02816.1 - 0.46 10.8 3.6 0.72 10.2 0.4 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KKA02816.1 - 0.63 10.3 8.3 0.23 11.7 2.3 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2H2_11 PF16622.5 KKA02816.1 - 0.7 9.7 4.7 3.3 7.6 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KKA02816.1 - 3.9 7.6 9.4 6.5 6.9 1.0 2.4 1 1 1 2 2 2 0 BED zinc finger Phos_pyr_kin PF08543.12 KKA02817.1 - 1.5e-06 27.8 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Aa_trans PF01490.18 KKA02818.1 - 1.2e-83 281.1 29.3 1.2e-83 281.1 29.3 1.7 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Fungal_trans PF04082.18 KKA02819.1 - 2.6e-12 46.3 4.6 2.6e-12 46.3 4.6 2.6 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA02819.1 - 6.9e-09 35.7 7.1 6.9e-09 35.7 7.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.22 KKA02819.1 - 0.026 14.7 1.1 0.12 12.6 1.1 2.1 1 0 0 1 1 1 0 Fasciclin domain Cytadhesin_P30 PF07271.11 KKA02819.1 - 0.093 12.3 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 MAGP PF05507.11 KKA02819.1 - 0.26 11.7 4.9 0.19 12.2 2.2 2.1 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Zn_clus PF00172.18 KKA02820.1 - 0.19 11.9 5.4 0.36 11.0 5.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KKA02821.1 - 8e-07 29.1 9.9 2.4e-06 27.6 9.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BC10 PF06726.12 KKA02821.1 - 0.0031 17.7 0.3 0.012 15.8 0.3 2.0 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 GDA1_CD39 PF01150.17 KKA02822.1 - 7.4e-103 344.5 0.3 9.4e-103 344.1 0.3 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF3443 PF11925.8 KKA02822.1 - 0.053 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Beta_elim_lyase PF01212.21 KKA02823.1 - 1.3e-72 244.6 0.0 1.6e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KKA02823.1 - 0.014 14.1 0.1 0.087 11.5 0.1 1.8 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DUF769 PF05590.11 KKA02824.1 - 0.026 14.0 0.4 0.053 12.9 0.2 1.6 2 0 0 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) Ribosomal_S21 PF01165.20 KKA02824.1 - 0.14 11.9 3.3 0.45 10.3 0.9 2.4 2 0 0 2 2 2 0 Ribosomal protein S21 GDI PF00996.18 KKA02825.1 - 6.5e-19 67.8 10.2 1e-18 67.1 10.2 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Fer4_12 PF13353.6 KKA02826.1 - 1.4 9.2 6.0 2 8.7 0.8 3.3 3 1 0 3 3 3 0 4Fe-4S single cluster domain E1-E2_ATPase PF00122.20 KKA02827.1 - 4.5e-21 75.2 0.1 8.2e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKA02827.1 - 3.9e-17 63.3 0.0 1e-11 45.5 0.2 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKA02827.1 - 2.1e-06 27.7 0.2 6.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKA02827.1 - 5.7e-05 23.0 0.2 0.0027 17.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KKA02827.1 - 0.0042 16.6 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Cation_ATPase_C PF00689.21 KKA02827.1 - 0.024 14.3 0.1 0.024 14.3 0.1 2.0 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus MCM PF00493.23 KKA02829.1 - 8.7e-96 319.3 0.1 1.9e-95 318.3 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKA02829.1 - 4e-26 91.3 0.0 1.1e-25 90.0 0.0 1.7 1 1 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKA02829.1 - 2.3e-22 79.2 4.1 5.1e-22 78.1 2.3 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KKA02829.1 - 1.7e-08 34.1 0.0 3.7e-07 29.7 0.0 3.0 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KKA02829.1 - 4.6e-07 30.4 0.2 1.1e-05 25.9 0.2 3.1 1 1 0 1 1 1 1 MCM N-terminal domain Sigma54_activat PF00158.26 KKA02829.1 - 0.00063 19.5 0.0 0.008 15.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KKA02829.1 - 0.001 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NAD_binding_7 PF13241.6 KKA02829.1 - 0.098 13.1 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AAA_5 PF07728.14 KKA02829.1 - 0.14 12.2 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) eIF-5a PF01287.20 KKA02830.1 - 1.8e-29 101.6 0.8 2.5e-29 101.1 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KKA02830.1 - 0.00043 20.3 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Anp1 PF03452.14 KKA02831.1 - 1.6e-109 365.4 0.0 2.4e-109 364.8 0.0 1.2 1 0 0 1 1 1 1 Anp1 GldH_lipo PF14109.6 KKA02831.1 - 0.014 16.2 1.0 0.052 14.3 0.1 2.1 2 0 0 2 2 2 0 GldH lipoprotein DUF3976 PF13121.6 KKA02831.1 - 0.11 12.6 0.3 0.28 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) UBA PF00627.31 KKA02832.1 - 9.5e-14 51.0 2.7 1.6e-07 31.1 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KKA02832.1 - 1.6e-10 40.6 0.3 4.3e-10 39.2 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KKA02832.1 - 2.2e-08 33.7 7.5 4.7e-05 23.0 0.4 3.2 3 0 0 3 3 3 2 XPC-binding domain Rad60-SLD PF11976.8 KKA02832.1 - 7.4e-05 22.5 0.3 0.00023 20.9 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKA02832.1 - 0.0021 18.6 0.1 0.021 15.4 0.0 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain eIF3_N PF09440.10 KKA02832.1 - 0.023 15.1 0.2 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain GerD PF17898.1 KKA02832.1 - 0.047 13.6 1.0 0.2 11.6 0.8 2.1 1 1 0 1 1 1 0 Spore germination GerD central core domain Rad60-SLD_2 PF13881.6 KKA02832.1 - 0.048 13.8 0.1 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 KKA02832.1 - 0.2 11.6 4.3 0.35 10.8 1.2 2.9 3 0 0 3 3 3 0 STI1 domain WTX PF09422.10 KKA02832.1 - 0.67 9.0 9.4 2 7.4 0.1 2.2 2 0 0 2 2 2 0 WTX protein Cytochrom_C PF00034.21 KKA02833.1 - 7.8e-12 46.2 0.2 1.7e-11 45.1 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KKA02833.1 - 4.8e-07 30.0 0.9 3.6e-06 27.2 0.9 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KKA02833.1 - 0.13 12.0 0.3 0.32 10.7 0.2 1.6 2 0 0 2 2 2 0 Cytochrome c-550 domain NAD_kinase PF01513.21 KKA02834.1 - 1.3e-80 270.8 0.0 1.8e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KKA02834.1 - 0.0031 17.1 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF4611 PF15387.6 KKA02834.1 - 1 9.6 4.8 17 5.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AAA_18 PF13238.6 KKA02834.1 - 2.2 8.9 5.0 1.2 9.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain DMAP1_like PF17024.5 KKA02835.1 - 0.0085 16.2 0.8 0.0085 16.2 0.8 2.2 2 1 0 2 2 2 1 Putative DMAP1-like Orthopox_A49R PF06489.11 KKA02835.1 - 0.023 14.9 2.5 0.039 14.2 2.5 1.4 1 0 0 1 1 1 0 Orthopoxvirus A49R protein ATP-synt_C PF00137.21 KKA02836.1 - 4e-34 116.8 30.5 2.4e-22 79.0 12.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 KKA02836.1 - 2.6 8.0 9.9 0.87 9.5 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Arteri_GP4 PF02497.15 KKA02837.1 - 0.018 15.2 1.7 0.19 11.8 0.2 2.7 3 0 0 3 3 3 0 Arterivirus glycoprotein Urb2 PF10441.9 KKA02839.1 - 2.2e-30 106.2 0.7 2.2e-30 106.2 0.7 2.2 3 0 0 3 3 3 1 Urb2/Npa2 family Voltage_CLC PF00654.20 KKA02840.1 - 1.9e-71 241.2 21.0 3.5e-56 191.0 14.0 3.0 3 0 0 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 KKA02840.1 - 4.2e-11 43.1 1.5 3.6e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF2868 PF11067.8 KKA02840.1 - 0.26 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) BPL_LplA_LipB PF03099.19 KKA02841.1 - 2.9e-05 24.0 0.1 4.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glycogen_syn PF05693.13 KKA02843.1 - 1.3e-296 985.4 0.2 1.5e-296 985.1 0.2 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KKA02843.1 - 6e-07 29.2 0.0 0.00025 20.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKA02843.1 - 1e-05 25.9 0.0 0.0051 17.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKA02843.1 - 2.2e-05 24.5 0.1 4.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KKA02843.1 - 0.0028 18.1 0.0 0.0059 17.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Ferric_reduct PF01794.19 KKA02846.1 - 1.9e-11 44.2 15.6 6.2e-11 42.5 15.6 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKA02846.1 - 2.3e-06 27.8 0.3 4.9e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KKA02846.1 - 0.0052 17.4 0.0 0.025 15.2 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KKA02846.1 - 0.024 14.7 0.1 0.06 13.4 0.1 1.7 1 0 0 1 1 1 0 FAD-binding domain DUF4405 PF14358.6 KKA02846.1 - 0.47 11.0 10.9 3.8 8.1 3.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) PfkB PF00294.24 KKA02847.1 - 1.6e-07 30.9 0.0 2.7e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mo25 PF08569.11 KKA02848.1 - 1.3e-66 225.3 29.7 1.4e-65 221.8 29.7 2.1 1 1 0 1 1 1 1 Mo25-like Alpha-amylase_C PF02806.18 KKA02849.1 - 3.3e-25 88.4 0.0 7.9e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KKA02849.1 - 2.2e-14 53.8 3.4 1.3e-13 51.2 0.2 3.0 2 1 1 3 3 3 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 KKA02849.1 - 1.7e-12 47.5 0.0 4.7e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.6 KKA02849.1 - 0.02 14.0 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 KKA02849.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RRM_1 PF00076.22 KKA02850.1 - 0.00012 21.8 0.1 0.00056 19.7 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 KKA02850.1 - 0.055 13.7 0.5 0.16 12.2 0.5 1.8 1 0 0 1 1 1 0 RNA recognition motif 2 MOZ_SAS PF01853.18 KKA02851.1 - 7.4e-35 120.2 2.2 1.7e-34 119.1 2.2 1.6 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKA02851.1 - 0.023 14.3 2.3 1.2 8.8 1.5 2.9 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2 PF00096.26 KKA02851.1 - 0.45 11.1 2.9 1.2 9.7 2.9 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Myb_DNA-binding PF00249.31 KKA02852.1 - 6.8e-10 39.0 0.3 1.2e-09 38.2 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA02852.1 - 4.4e-09 36.4 0.9 8.7e-09 35.5 0.9 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Meth_synt_2 PF01717.18 KKA02853.1 - 5.6e-151 502.4 0.0 3.3e-145 483.4 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKA02853.1 - 3.1e-118 394.8 0.0 6.7e-110 367.5 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain RVT_connect PF06815.13 KKA02853.1 - 0.09 13.0 0.3 16 5.9 0.0 3.1 3 0 0 3 3 3 0 Reverse transcriptase connection domain DUF3502 PF12010.8 KKA02853.1 - 0.17 12.5 1.0 5.7 7.6 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3502) PP2C PF00481.21 KKA02854.1 - 2.9e-67 227.0 0.0 1.7e-66 224.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C TatD_DNase PF01026.21 KKA02855.1 - 5.7e-31 107.8 0.0 7.1e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Chorismate_bind PF00425.18 KKA02856.1 - 1.3e-92 310.0 0.0 4.9e-92 308.1 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KKA02856.1 - 1.9e-25 89.7 0.7 4.4e-23 82.1 0.0 3.4 3 1 0 4 4 4 1 Anthranilate synthase component I, N terminal region IES5 PF17335.2 KKA02856.1 - 0.024 14.9 0.6 0.081 13.2 0.1 2.1 2 0 0 2 2 2 0 Ino80 complex subunit 5 Erf4 PF10256.9 KKA02856.1 - 0.13 12.4 0.5 5.1 7.2 0.0 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family PTH2 PF01981.16 KKA02857.1 - 9.1e-41 138.8 0.1 1.3e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ANAPC9 PF12856.7 KKA02857.1 - 0.1 12.8 1.3 0.16 12.1 1.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 RICTOR_N PF14664.6 KKA02858.1 - 2.3e-50 171.7 12.2 2.3e-50 171.7 12.2 2.8 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 KKA02858.1 - 6.6e-20 71.1 2.1 3.2e-18 65.7 0.7 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 KKA02858.1 - 7.1e-18 64.3 1.2 7.1e-18 64.3 1.2 4.2 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KKA02858.1 - 6.7e-13 49.0 0.5 6.7e-13 49.0 0.5 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain CDT1_C PF16679.5 KKA02858.1 - 0.026 15.0 0.3 0.38 11.2 0.0 3.1 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Lzipper-MIP1 PF14389.6 KKA02858.1 - 0.22 11.9 6.4 0.25 11.7 3.5 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Rad51 PF08423.11 KKA02859.1 - 1.3e-122 408.0 0.0 2.2e-122 407.2 0.0 1.4 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 KKA02859.1 - 1.4e-13 51.0 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KKA02859.1 - 4e-10 39.6 0.0 6.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KKA02859.1 - 8.4e-05 22.0 0.2 0.00026 20.4 0.2 1.9 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KKA02859.1 - 0.00027 21.5 0.1 0.00083 19.9 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KKA02859.1 - 0.0005 19.5 0.1 0.0062 15.9 0.0 2.6 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KKA02859.1 - 0.017 14.3 0.5 0.31 10.1 0.2 2.3 2 0 0 2 2 2 0 PAXNEB protein Sel1 PF08238.12 KKA02860.1 - 1.1e-37 127.5 0.4 2e-06 28.3 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.6 KKA02860.1 - 0.045 13.4 0.5 5 6.9 0.0 3.2 3 0 0 3 3 3 0 TPR repeat tRNA-synt_1 PF00133.22 KKA02861.1 - 1.3e-237 789.9 0.6 2e-237 789.3 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKA02861.1 - 1.3e-24 86.9 0.9 4.9e-24 85.0 0.0 2.4 2 1 1 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKA02861.1 - 1.5e-17 63.5 0.9 2.3e-05 23.3 0.3 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKA02861.1 - 1.2e-05 24.9 0.6 0.0028 17.0 0.0 3.4 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain CbiK PF06180.11 KKA02861.1 - 0.03 13.7 0.1 0.08 12.2 0.1 1.7 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Queuosine_synth PF02547.15 KKA02862.1 - 0.035 13.2 0.2 0.071 12.2 0.0 1.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein Med28 PF11594.8 KKA02862.1 - 0.046 13.8 0.3 0.14 12.2 0.2 1.8 1 1 0 1 1 1 0 Mediator complex subunit 28 RETICULATA-like PF11891.8 KKA02863.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein RETICULATA-related Ribosomal_S8e PF01201.22 KKA02864.1 - 2e-56 190.0 3.6 2.3e-56 189.7 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e UQ_con PF00179.26 KKA02865.1 - 1.5e-13 50.6 0.9 2.1e-13 50.1 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme ADH_zinc_N_2 PF13602.6 KKA02866.1 - 1.5e-09 39.0 0.0 3.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKA02866.1 - 6.6e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pribosyltran_N PF13793.6 KKA02867.1 - 3e-36 123.9 0.6 2.2e-35 121.1 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKA02867.1 - 9e-34 117.1 0.5 2.5e-30 105.9 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKA02867.1 - 6.9e-16 58.2 0.6 2.6e-15 56.3 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKA02867.1 - 0.00016 21.2 0.2 0.00047 19.7 0.1 1.8 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF2007 PF09413.10 KKA02867.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein Got1 PF04178.12 KKA02868.1 - 5.2e-30 104.2 17.3 8.1e-30 103.6 17.3 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3959 PF13105.6 KKA02868.1 - 2.1 7.8 7.5 3 7.3 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF2070 PF09843.9 KKA02868.1 - 2.5 6.3 11.5 3.1 6.0 11.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Arrestin_C PF02752.22 KKA02869.1 - 8.7e-12 45.6 0.0 5.8e-11 43.0 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pyridoxal_deC PF00282.19 KKA02870.1 - 4.6e-11 42.1 0.0 7.6e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RNA_pol_Rpb4 PF03874.16 KKA02872.1 - 1.4e-16 60.9 31.4 2.2e-12 47.4 2.3 4.1 2 1 1 3 3 3 2 RNA polymerase Rpb4 STAC2_u1 PF16664.5 KKA02872.1 - 0.34 11.4 5.4 0.17 12.4 2.4 2.1 1 1 1 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Glyco_transf_15 PF01793.16 KKA02873.1 - 1e-55 189.3 19.2 1e-55 189.3 19.2 2.0 1 1 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase DEAD PF00270.29 KKA02874.1 - 1.6e-42 145.3 0.8 1.6e-42 145.3 0.8 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02874.1 - 1.4e-31 109.1 0.6 4.1e-31 107.6 0.2 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02874.1 - 3.3e-08 33.7 0.6 6e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKA02874.1 - 0.0018 18.0 0.2 0.0036 17.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 KKA02874.1 - 0.0032 16.8 0.4 0.014 14.8 0.0 2.2 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 KKA02874.1 - 0.0034 17.7 0.7 0.019 15.3 0.5 2.1 2 1 0 2 2 2 1 AAA domain Ribosomal_L10 PF00466.20 KKA02874.1 - 0.01 15.9 0.5 0.56 10.4 0.1 2.8 1 1 1 2 2 2 0 Ribosomal protein L10 Flavi_DEAD PF07652.14 KKA02874.1 - 0.014 15.3 0.2 0.2 11.7 0.2 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain DNA_III_psi PF03603.13 KKA02874.1 - 0.046 13.9 0.9 0.28 11.4 0.1 2.5 2 1 1 3 3 3 0 DNA polymerase III psi subunit DUF3770 PF12603.8 KKA02874.1 - 0.088 12.3 0.3 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) PhoH PF02562.16 KKA02874.1 - 0.12 11.8 0.8 0.43 10.0 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein PAP2 PF01569.21 KKA02875.1 - 9.3e-18 64.3 1.5 2.4e-17 63.0 1.5 1.6 1 0 0 1 1 1 1 PAP2 superfamily DUF3453 PF11935.8 KKA02875.1 - 0.002 17.8 0.4 0.0033 17.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF212 PF02681.14 KKA02875.1 - 0.0054 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Divergent PAP2 family Mito_carr PF00153.27 KKA02876.1 - 7.2e-59 195.7 2.1 1.2e-21 76.4 0.3 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKA02876.1 - 0.0002 20.6 0.1 0.12 11.5 0.0 2.7 3 0 0 3 3 3 2 Gammaproteobacterial serine protease Scm3 PF10384.9 KKA02876.1 - 0.17 11.6 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 Pkinase PF00069.25 KKA02878.1 - 1.9e-58 197.9 0.0 2.5e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02878.1 - 3.6e-35 121.5 0.0 5.8e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02878.1 - 0.00031 20.1 0.0 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KKA02878.1 - 0.0098 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KKA02878.1 - 0.017 13.9 0.4 0.045 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase MG1 PF17790.1 KKA02880.1 - 1.3 9.5 5.7 0.53 10.7 0.1 3.2 3 0 0 3 3 3 0 Macroglobulin domain MG1 Hamartin PF04388.12 KKA02881.1 - 1.5 7.4 13.2 1.6 7.3 13.2 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 KKA02881.1 - 2.6 6.8 15.1 2.9 6.7 15.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ashwin PF15323.6 KKA02881.1 - 2.8 7.9 12.7 3.7 7.5 12.7 1.4 1 0 0 1 1 1 0 Developmental protein Ran_BP1 PF00638.18 KKA02882.1 - 0.028 14.7 0.5 3.2 8.0 0.0 2.3 1 1 0 2 2 2 0 RanBP1 domain DUF4387 PF14330.6 KKA02882.1 - 0.17 12.6 0.6 1.6 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4387) Lipoprotein_6 PF01441.19 KKA02883.1 - 0.083 12.9 3.7 0.92 9.5 0.2 3.1 3 0 0 3 3 3 0 Lipoprotein Pox_VLTF3 PF04947.14 KKA02884.1 - 0.0049 16.6 3.2 0.0049 16.6 3.2 1.7 2 0 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like Pkinase PF00069.25 KKA02885.1 - 3.6e-61 206.9 0.2 5e-61 206.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02885.1 - 5.5e-25 88.1 0.0 7.9e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKA02885.1 - 0.0011 19.0 0.2 0.074 13.0 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKA02885.1 - 0.0028 17.0 0.3 0.0049 16.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4488 PF14869.6 KKA02885.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Pkinase_fungal PF17667.1 KKA02885.1 - 0.096 11.4 0.7 1 8.1 0.0 2.1 1 1 1 2 2 2 0 Fungal protein kinase FAS_meander PF17951.1 KKA02885.1 - 0.12 12.1 1.0 0.25 11.2 1.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain TPP_enzyme_N PF02776.18 KKA02886.1 - 8.7e-28 97.1 0.0 1.3e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKA02886.1 - 4.6e-25 88.0 0.0 9e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKA02886.1 - 2.2e-14 53.5 0.1 4e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aminotran_3 PF00202.21 KKA02887.1 - 2.8e-54 184.3 0.0 3.3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.21 KKA02888.1 - 9.6e-61 205.6 0.0 1.2e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III WW_like PF17890.1 KKA02888.1 - 0.11 12.5 0.9 0.81 9.8 0.1 2.4 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain Aminotran_3 PF00202.21 KKA02889.1 - 3.1e-61 207.3 0.0 4.1e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Tautomerase PF01361.21 KKA02889.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme PRY PF13765.6 KKA02890.1 - 0.0015 18.1 0.0 0.005 16.5 0.0 1.9 1 0 0 1 1 1 1 SPRY-associated domain UIM PF02809.20 KKA02890.1 - 0.0036 17.1 3.4 0.0094 15.8 3.4 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-C3HC4_3 PF13920.6 KKA02890.1 - 0.042 13.7 9.6 0.031 14.1 4.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.19 KKA02891.1 - 1.9e-22 79.6 11.6 2.3e-22 79.4 11.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DEAD PF00270.29 KKA02892.1 - 2.2e-36 125.3 1.0 1.1e-35 123.0 0.3 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA02892.1 - 4e-26 91.5 0.3 3.4e-25 88.6 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02892.1 - 1.8e-08 34.6 0.1 7.1e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KKA02892.1 - 0.03 14.9 0.2 0.14 12.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Glutaredoxin PF00462.24 KKA02892.1 - 0.067 13.4 0.0 2.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Glutaredoxin Histidinol_dh PF00815.20 KKA02893.1 - 0.057 12.4 1.5 0.12 11.4 1.5 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase PhoLip_ATPase_C PF16212.5 KKA02894.1 - 5.2e-64 216.4 24.5 5.2e-64 216.4 24.5 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKA02894.1 - 3.4e-21 74.7 1.8 3.4e-21 74.7 1.8 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKA02894.1 - 8.7e-13 49.0 2.2 4.6e-06 27.1 0.1 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKA02894.1 - 4.7e-12 45.8 0.4 2.4e-10 40.4 0.0 3.3 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KKA02894.1 - 6.9e-12 45.3 0.0 3e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase DnaJ PF00226.31 KKA02895.1 - 4.9e-17 61.8 5.7 7.4e-17 61.2 5.7 1.3 1 0 0 1 1 1 1 DnaJ domain Innate_immun PF12782.7 KKA02895.1 - 0.16 11.5 9.5 0.22 11.0 9.5 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DNA_pol_B PF00136.21 KKA02896.1 - 6.2e-145 483.4 1.2 9.7e-145 482.8 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKA02896.1 - 7.7e-79 265.3 1.5 1.1e-78 264.7 0.8 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKA02896.1 - 3.7e-16 59.4 8.8 7.5e-16 58.4 8.8 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KKA02896.1 - 0.003 16.5 2.3 0.003 16.5 2.3 3.6 2 1 1 3 3 3 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KKA02896.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Fcf2 PF08698.11 KKA02896.1 - 0.099 13.1 0.3 0.44 11.0 0.0 2.3 2 1 0 2 2 2 0 Fcf2 pre-rRNA processing RecR PF02132.15 KKA02896.1 - 1.4 8.6 5.0 0.19 11.3 0.3 2.1 2 0 0 2 2 2 0 RecR protein zf-ACC PF17848.1 KKA02896.1 - 1.8 8.7 11.7 0.65 10.1 4.1 3.1 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain PNK3P PF08645.11 KKA02899.1 - 9.9e-32 109.9 12.8 3.7e-31 108.0 12.8 1.9 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Microtub_bd PF16796.5 KKA02899.1 - 0.019 14.9 3.6 0.022 14.7 1.9 2.1 1 1 1 2 2 2 0 Microtubule binding LUC7 PF03194.15 KKA02900.1 - 3e-08 33.7 4.0 3e-08 33.7 4.0 3.6 3 2 0 3 3 3 1 LUC7 N_terminus Malic_M PF03949.15 KKA02900.1 - 0.047 13.0 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Peptidase_S24 PF00717.23 KKA02901.1 - 7.3e-06 25.9 0.8 6.6e-05 22.8 0.1 2.8 2 2 1 3 3 3 1 Peptidase S24-like Peptidase_S26 PF10502.9 KKA02901.1 - 0.025 14.3 0.0 0.35 10.7 0.0 2.2 2 1 0 2 2 2 0 Signal peptidase, peptidase S26 GCV_H PF01597.19 KKA02902.1 - 6e-29 100.4 2.0 8.1e-29 100.0 2.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF2129 PF09902.9 KKA02902.1 - 0.091 12.8 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) WD40 PF00400.32 KKA02903.1 - 1.6e-22 79.3 0.0 1.9e-07 31.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA02903.1 - 1.8e-08 34.6 0.0 0.29 11.4 0.0 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKA02903.1 - 1.2e-05 24.5 0.0 0.22 10.4 0.0 3.2 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKA02903.1 - 3.3e-05 23.9 0.3 1.9 8.3 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKA02903.1 - 0.00061 18.6 0.0 0.48 9.0 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Pyr_redox_2 PF07992.14 KKA02904.1 - 1.2e-45 156.0 0.1 1.4e-45 155.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKA02904.1 - 2.9e-13 50.2 0.0 1.2e-11 45.0 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKA02904.1 - 0.061 12.6 0.1 0.69 9.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKA02904.1 - 0.072 13.1 0.1 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KKA02904.1 - 0.13 11.8 0.4 22 4.5 0.1 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase Aldedh PF00171.22 KKA02905.1 - 5.3e-158 526.3 0.0 6.4e-158 526.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKA02905.1 - 0.00013 21.2 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pkinase PF00069.25 KKA02907.1 - 1.6e-64 217.9 0.3 1.9e-64 217.6 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02907.1 - 3.4e-32 111.7 0.3 6.9e-32 110.7 0.3 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02907.1 - 3.7e-09 36.3 0.0 5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKA02907.1 - 0.0001 21.4 0.6 0.00017 20.7 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKA02907.1 - 0.0034 17.3 0.0 0.0067 16.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKA02907.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 KKA02908.1 - 0.00015 21.4 14.6 0.016 15.0 0.9 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKA02908.1 - 0.00027 21.2 0.4 0.23 11.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PIEZO PF15917.5 KKA02908.1 - 0.0028 17.2 1.9 0.13 11.7 0.7 2.3 2 0 0 2 2 2 1 Piezo TPR_8 PF13181.6 KKA02908.1 - 0.066 13.5 13.0 1.3 9.5 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA02908.1 - 0.078 13.2 3.3 5.1 7.4 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KKA02908.1 - 0.1 12.5 0.2 0.41 10.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKA02908.1 - 0.12 12.5 11.4 0.27 11.4 0.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KKA02908.1 - 0.23 11.8 0.9 13 6.3 0.0 3.6 3 0 0 3 3 3 0 PPR repeat Cys_Met_Meta_PP PF01053.20 KKA02909.1 - 3.1e-55 187.3 0.0 8e-55 185.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKA02909.1 - 0.00053 19.0 0.0 0.00091 18.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SepF PF04472.12 KKA02909.1 - 0.055 13.8 0.1 16 5.9 0.1 2.6 2 0 0 2 2 2 0 Cell division protein SepF Aminotran_1_2 PF00155.21 KKA02909.1 - 0.084 12.0 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SPRY PF00622.28 KKA02910.1 - 3.6e-12 46.4 0.1 1.2e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 SPRY domain Spt5-NGN PF03439.13 KKA02910.1 - 0.0066 16.3 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section YL1 PF05764.13 KKA02910.1 - 0.35 11.0 8.9 0.55 10.3 8.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Aldedh PF00171.22 KKA02911.1 - 2.9e-154 514.0 0.1 3.3e-154 513.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PX PF00787.24 KKA02912.1 - 9.7e-11 41.7 2.6 2.9e-10 40.1 0.6 2.8 2 1 0 2 2 2 1 PX domain LOH1CR12 PF10158.9 KKA02912.1 - 0.045 13.8 1.8 0.12 12.4 0.1 2.6 3 0 0 3 3 3 0 Tumour suppressor protein DUF2654 PF10849.8 KKA02912.1 - 0.15 12.3 0.1 0.15 12.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2654) Ribosomal_L6 PF00347.23 KKA02913.1 - 1.5e-26 92.9 9.5 7.3e-14 52.2 1.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.12 KKA02913.1 - 0.032 14.6 5.4 4.8 7.6 4.0 2.9 1 1 1 2 2 2 0 YbbR-like protein SNF2_N PF00176.23 KKA02914.1 - 7.6e-63 212.3 2.8 7.6e-63 212.3 2.8 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KKA02914.1 - 3.6e-32 111.5 19.4 3.6e-32 111.5 19.4 3.3 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KKA02914.1 - 3.9e-20 72.3 0.1 3.1e-19 69.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA02914.1 - 3.5e-08 33.6 0.0 3.5e-08 33.6 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ACPS PF01648.20 KKA02915.1 - 7.8e-11 42.1 0.0 2.1e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Prenyltrans PF00432.21 KKA02915.1 - 5.7e-09 35.6 0.1 0.0025 17.5 0.0 2.6 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat DFP PF04127.15 KKA02917.1 - 2.6e-19 69.8 0.0 6.5e-09 35.9 0.2 2.6 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein MCM_N PF14551.6 KKA02917.1 - 0.061 13.9 0.5 0.14 12.7 0.5 1.7 1 0 0 1 1 1 0 MCM N-terminal domain Glyco_transf_15 PF01793.16 KKA02919.1 - 2.4e-79 267.0 21.9 3.3e-51 174.5 11.6 2.4 2 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Histone PF00125.24 KKA02920.1 - 4.6e-48 162.9 6.0 5.2e-48 162.7 6.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKA02920.1 - 1.5e-06 28.5 0.1 2.3e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KKA02920.1 - 1.3e-05 25.8 2.4 1.5e-05 25.6 2.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KKA02920.1 - 0.00011 22.3 0.3 0.00011 22.3 0.3 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KKA02920.1 - 0.004 17.4 0.1 0.004 17.4 0.1 1.9 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKA02920.1 - 0.039 14.0 0.2 0.062 13.4 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Tombus_movement PF05318.12 KKA02920.1 - 3 8.7 5.7 6.8 7.6 5.7 1.6 1 0 0 1 1 1 0 Tombusvirus movement protein Aim19 PF10315.9 KKA02921.1 - 5.2e-09 36.4 0.5 7e-09 36.0 0.5 1.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Y_phosphatase2 PF03162.13 KKA02922.1 - 7.1e-58 194.8 1.5 9.9e-58 194.4 0.2 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KKA02922.1 - 1.2e-07 32.0 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KKA02922.1 - 0.00075 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KKA02922.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain STN PF07660.14 KKA02922.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain PTPlike_phytase PF14566.6 KKA02922.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Aa_trans PF01490.18 KKA02923.1 - 1.7e-67 228.0 40.1 1.9e-67 227.8 40.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KKA02923.1 - 2.6e-05 23.4 16.5 2.6e-05 23.4 16.5 2.8 2 1 1 3 3 3 2 Tryptophan/tyrosine permease family Iso_dh PF00180.20 KKA02924.1 - 7.5e-25 87.8 0.5 9.2e-25 87.5 0.5 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YscJ_FliF PF01514.17 KKA02924.1 - 0.0018 17.9 1.0 0.0032 17.2 1.0 1.3 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family Pkinase PF00069.25 KKA02925.1 - 3.9e-42 144.4 0.0 3.9e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02925.1 - 6e-26 91.3 0.8 7.2e-26 91.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02925.1 - 3.2e-06 26.7 0.0 1.2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKA02925.1 - 4.7e-05 22.5 0.1 4.7e-05 22.5 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain zf-CRD PF17979.1 KKA02925.1 - 0.095 12.8 1.8 0.24 11.5 1.8 1.7 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions PP_kinase_N PF13089.6 KKA02925.1 - 0.097 13.0 1.6 0.24 11.8 1.6 1.6 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain Methyltr_RsmB-F PF01189.17 KKA02926.1 - 1e-16 61.2 0.1 6.2e-12 45.6 0.1 3.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F ICE2 PF08426.10 KKA02927.1 - 1.2e-103 347.4 33.5 9e-66 222.7 15.1 2.1 2 0 0 2 2 2 2 ICE2 DUF1761 PF08570.10 KKA02927.1 - 0.25 11.6 4.6 1.6 9.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) Cyclin_N PF00134.23 KKA02928.1 - 2.1e-14 53.4 1.0 2.1e-14 53.4 1.0 2.1 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KKA02928.1 - 0.027 14.9 0.0 0.081 13.3 0.0 1.9 1 0 0 1 1 1 0 Cyclin C-terminal domain TRAM_LAG1_CLN8 PF03798.16 KKA02929.1 - 2.9e-13 50.0 11.2 2.9e-13 50.0 11.2 2.7 2 1 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 KKA02930.1 - 3.9e-10 39.8 7.2 5e-10 39.4 7.2 1.1 1 0 0 1 1 1 1 TLC domain TRAP_alpha PF03896.16 KKA02930.1 - 0.0033 16.7 0.9 0.0054 16.0 0.9 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit FHIPEP PF00771.20 KKA02930.1 - 0.011 14.3 0.2 0.016 13.7 0.2 1.2 1 0 0 1 1 1 0 FHIPEP family TMEM208_SND2 PF05620.11 KKA02930.1 - 0.019 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 FAM176 PF14851.6 KKA02930.1 - 0.043 13.5 0.4 0.068 12.8 0.4 1.3 1 0 0 1 1 1 0 FAM176 family DUF2530 PF10745.9 KKA02930.1 - 0.26 11.6 2.4 0.9 9.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Diphthamide_syn PF01866.17 KKA02931.1 - 2.4e-113 378.6 0.2 3.2e-113 378.2 0.2 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein BRF1 PF07741.13 KKA02932.1 - 0.099 13.0 2.3 0.13 12.7 0.2 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain SHQ1 PF04925.15 KKA02933.1 - 1.2e-31 109.6 0.7 1.2e-31 109.6 0.7 3.3 2 2 0 2 2 2 1 SHQ1 protein E1_4HB PF16191.5 KKA02933.1 - 0.17 12.1 0.9 2.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle DUF2722 PF10846.8 KKA02934.1 - 2.3e-13 50.0 6.9 2.3e-13 50.0 6.9 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) ALG11_N PF15924.5 KKA02935.1 - 3.2e-65 220.1 6.3 1e-63 215.2 6.3 2.2 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KKA02935.1 - 1.3e-11 44.3 0.2 3.4e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKA02935.1 - 0.00071 19.6 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Peptidase_M1 PF01433.20 KKA02936.1 - 6.8e-28 97.7 0.8 1.2e-27 96.9 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KKA02936.1 - 1.3e-25 90.7 0.4 2.7e-25 89.6 0.4 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Leuk-A4-hydro_C PF09127.11 KKA02936.1 - 2.1e-19 69.7 0.2 2.3e-18 66.3 0.1 2.3 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal ChaB PF06150.12 KKA02937.1 - 0.21 12.2 2.4 0.39 11.3 1.0 2.0 2 0 0 2 2 2 0 ChaB Sec23_trunk PF04811.15 KKA02938.1 - 2.4e-60 204.1 0.0 4e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKA02938.1 - 2.2e-17 62.8 0.5 1.1e-16 60.5 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKA02938.1 - 3.1e-14 53.5 0.0 8.1e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKA02938.1 - 7.7e-12 45.1 6.2 2.1e-11 43.7 6.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKA02938.1 - 8.5e-09 35.2 0.0 2.6e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat DUF5035 PF16438.5 KKA02938.1 - 0.0093 15.8 0.0 0.034 14.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5035) dCMP_cyt_deam_1 PF00383.23 KKA02939.1 - 3.3e-26 91.1 4.7 3.3e-26 91.1 4.7 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKA02939.1 - 4.1e-16 59.0 0.6 1.2e-15 57.4 0.6 1.8 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KKA02939.1 - 0.086 13.0 2.1 0.29 11.2 2.1 1.9 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KKA02939.1 - 1.2 9.3 4.6 1.1 9.4 0.6 2.4 2 0 0 2 2 2 0 APOBEC3 SHR3_chaperone PF08229.11 KKA02940.1 - 3.2e-51 173.0 1.1 3.9e-51 172.7 1.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 LapA_dom PF06305.11 KKA02940.1 - 0.0029 17.4 1.7 0.0082 15.9 0.5 2.3 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain CitMHS_2 PF16980.5 KKA02940.1 - 0.0062 15.2 0.1 0.0077 14.9 0.1 1.2 1 0 0 1 1 1 1 Putative citrate transport Bac_export_2 PF01312.19 KKA02940.1 - 0.024 13.9 0.3 0.037 13.2 0.1 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF1980 PF09323.10 KKA02940.1 - 0.032 14.1 0.2 0.063 13.2 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Tetraspanin PF00335.20 KKA02940.1 - 0.11 12.2 5.6 2.4 7.8 3.6 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF2970 PF11174.8 KKA02940.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) FtsL PF04999.13 KKA02940.1 - 0.56 10.2 3.0 7.4 6.7 0.1 2.8 2 1 1 3 3 3 0 Cell division protein FtsL DUF4709 PF15821.5 KKA02941.1 - 1.3 9.3 8.9 2.6 8.3 1.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4709) ABC_tran_CTD PF16326.5 KKA02941.1 - 1.9 8.8 16.5 11 6.3 0.2 4.6 4 0 0 4 4 4 0 ABC transporter C-terminal domain Aminotran_1_2 PF00155.21 KKA02943.1 - 7.4e-09 35.2 0.0 9.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GbpC PF08363.10 KKA02943.1 - 0.04 13.4 0.3 0.054 12.9 0.3 1.2 1 0 0 1 1 1 0 Glucan-binding protein C Activator-TraM PF11657.8 KKA02943.1 - 0.22 11.3 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Aminotran_1_2 PF00155.21 KKA02944.1 - 2.7e-05 23.5 0.0 3.7e-05 23.1 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 KKA02945.1 - 3.3e-16 59.4 0.0 5.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 KKA02947.1 - 0.0054 16.5 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KKA02948.1 - 1.9e-26 93.0 0.6 4.4e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02948.1 - 1.7e-13 50.5 0.4 3.6e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKA02948.1 - 1.5e-08 33.8 2.5 3.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KKA02948.1 - 0.00026 21.0 1.1 0.21 11.5 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family SUIM_assoc PF16619.5 KKA02948.1 - 0.0026 17.8 2.2 0.0026 17.8 2.2 3.5 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Exonuc_VII_L PF02601.15 KKA02948.1 - 7.3 6.1 12.4 15 5.1 12.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.32 KKA02949.1 - 1.3e-05 25.8 0.7 0.072 14.0 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Bap31_Bap29_C PF18035.1 KKA02949.1 - 0.035 14.1 1.3 0.075 13.0 1.3 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pkinase PF00069.25 KKA02950.1 - 7.2e-45 153.4 0.0 1.4e-44 152.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02950.1 - 2.3e-22 79.5 0.0 4.4e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KKA02950.1 - 0.096 12.3 0.2 0.57 9.8 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKA02950.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KKA02950.1 - 0.25 11.2 0.1 0.49 10.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11 PF00298.19 KKA02951.1 - 5.3e-24 84.5 0.6 1.1e-23 83.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KKA02951.1 - 2.1e-23 81.9 0.5 3.4e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain ELFV_dehydrog PF00208.21 KKA02952.1 - 6.6e-60 202.8 0.0 1.2e-59 202.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KKA02952.1 - 5.3e-21 74.0 0.5 5.7e-15 54.0 0.0 2.7 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase MFS_1 PF07690.16 KKA02953.1 - 1.4e-31 109.7 43.7 1.4e-28 99.9 27.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Synaptobrevin PF00957.21 KKA02953.1 - 2.4 8.0 4.8 3.4 7.5 0.8 2.8 2 0 0 2 2 2 0 Synaptobrevin Tim17 PF02466.19 KKA02954.1 - 9.3e-39 132.2 2.1 1.1e-38 132.0 2.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABC2_membrane_3 PF12698.7 KKA02955.1 - 0.0067 15.6 2.3 0.0079 15.3 2.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein MARVEL PF01284.23 KKA02957.1 - 3.3e-15 56.4 14.5 4.8e-15 55.9 14.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3687 PF12459.8 KKA02957.1 - 0.01 15.3 1.4 0.018 14.5 0.2 2.0 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein TPR_11 PF13414.6 KKA02958.1 - 0.0017 18.0 0.7 0.004 16.8 0.1 2.0 2 0 0 2 2 2 1 TPR repeat PAH PF02671.21 KKA02958.1 - 0.37 11.0 4.2 20 5.4 0.4 3.4 3 1 0 3 3 3 0 Paired amphipathic helix repeat Chitin_synth_1 PF01644.17 KKA02959.1 - 3.5e-66 222.2 0.0 7.3e-66 221.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKA02959.1 - 2.2e-24 85.2 0.1 6.8e-24 83.6 0.1 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKA02959.1 - 1e-16 60.7 12.2 4.6e-12 45.3 4.3 3.2 1 1 3 4 4 4 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKA02959.1 - 1.2e-08 35.1 1.6 1.2e-08 35.1 1.6 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF3989 PF13150.6 KKA02959.1 - 0.52 10.1 2.6 0.67 9.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) SUR7 PF06687.12 KKA02961.1 - 1.9e-33 115.9 13.2 2.9e-33 115.3 13.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family RRM_1 PF00076.22 KKA02962.1 - 2.9e-10 39.8 0.0 1e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRRFIP PF09738.9 KKA02962.1 - 0.057 12.9 2.7 0.13 11.7 2.7 1.5 1 0 0 1 1 1 0 LRRFIP family Septin PF00735.18 KKA02963.1 - 1.5e-57 195.0 8.9 1.5e-57 195.0 8.9 2.4 2 2 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KKA02963.1 - 0.0042 17.2 0.7 0.0042 17.2 0.7 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KKA02963.1 - 0.02 14.3 0.0 0.077 12.4 0.0 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 KKA02963.1 - 0.048 13.0 3.4 0.11 11.8 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family SurA_N_3 PF13624.6 KKA02964.1 - 0.008 16.0 11.3 0.29 10.9 0.2 4.8 4 1 1 5 5 5 2 SurA N-terminal domain Y_phosphatase2 PF03162.13 KKA02965.1 - 3e-51 173.3 0.0 3.5e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KKA02965.1 - 0.0001 22.4 0.0 0.00026 21.0 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KKA02965.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain N2227 PF07942.12 KKA02965.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Y_phosphatase PF00102.27 KKA02965.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DAD PF02109.16 KKA02966.1 - 5.1e-27 94.3 3.5 5.1e-27 94.3 3.5 1.5 2 0 0 2 2 2 1 DAD family PalH PF08733.10 KKA02966.1 - 6.6e-05 22.1 3.2 6.8e-05 22.0 3.2 1.2 1 0 0 1 1 1 1 PalH/RIM21 Peptidase_M28 PF04389.17 KKA02967.1 - 5.2e-22 78.5 0.0 1.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKA02967.1 - 0.026 14.2 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ATP-synt_D PF01813.17 KKA02968.1 - 6.6e-61 205.6 4.1 6.6e-61 205.6 4.1 1.7 2 0 0 2 2 2 1 ATP synthase subunit D Ribosomal_L6e PF01159.19 KKA02968.1 - 3.8 8.1 15.4 5e+02 1.3 15.4 2.6 1 1 0 1 1 1 0 Ribosomal protein L6e Sod_Fe_C PF02777.18 KKA02969.1 - 5.6e-08 32.9 0.1 4.8e-05 23.5 0.1 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Cauli_AT PF03233.13 KKA02969.1 - 0.00047 20.1 3.1 0.23 11.4 0.8 2.4 2 0 0 2 2 2 2 Aphid transmission protein DarA_N PF18788.1 KKA02969.1 - 0.023 14.8 0.7 0.16 12.0 0.1 2.4 3 1 0 3 3 3 0 Defence against restriction A N-terminal Sod_Fe_N PF00081.22 KKA02969.1 - 0.076 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2019 PF09450.10 KKA02969.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) ESCRT-II PF05871.12 KKA02970.1 - 3.9e-19 69.3 3.2 1.7e-18 67.2 3.2 2.0 1 1 0 1 1 1 1 ESCRT-II complex subunit CTP_synth_N PF06418.14 KKA02971.1 - 7.1e-122 405.8 0.6 9.4e-122 405.4 0.6 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KKA02971.1 - 1.5e-55 187.9 0.0 2.7e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKA02971.1 - 0.0098 15.7 0.2 0.17 11.6 0.1 2.7 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 KKA02971.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PNP_phzG_C PF10590.9 KKA02973.1 - 2.1e-19 69.3 1.4 4.9e-19 68.1 1.4 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KKA02973.1 - 9.4e-13 48.2 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KKA02973.1 - 0.0051 16.4 0.3 0.26 10.8 0.0 2.7 2 1 1 3 3 3 1 Pyridoxamine 5'-phosphate oxidase like Pyridox_oxase_2 PF12766.7 KKA02973.1 - 0.042 14.5 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Proteasome PF00227.26 KKA02975.1 - 1.3e-26 93.2 0.5 1.6e-18 66.9 0.1 3.7 1 1 1 2 2 2 2 Proteasome subunit DnaJ PF00226.31 KKA02976.1 - 1.9e-15 56.7 2.1 3.8e-15 55.7 2.1 1.6 1 0 0 1 1 1 1 DnaJ domain SurA_N_3 PF13624.6 KKA02976.1 - 0.035 13.9 2.9 1.6 8.5 1.5 2.4 2 0 0 2 2 2 0 SurA N-terminal domain KLRAQ PF10205.9 KKA02976.1 - 0.061 13.6 5.5 0.092 13.0 4.5 1.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein UQ_con PF00179.26 KKA02977.1 - 6.3e-38 129.6 0.0 8.8e-38 129.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Meiotic_rec114 PF03525.14 KKA02977.1 - 0.026 13.5 0.5 0.038 12.9 0.5 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 Sugar_tr PF00083.24 KKA02978.1 - 1.1e-149 499.1 34.2 1.3e-149 498.9 34.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA02978.1 - 4.8e-29 101.4 38.3 4.2e-26 91.7 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1 PF08622.10 KKA02979.1 - 8.6e-52 175.5 1.0 8.6e-52 175.5 1.0 1.6 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 KKA02979.1 - 1.8e-44 151.5 0.9 3.1e-44 150.7 0.9 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain p450 PF00067.22 KKA02980.1 - 8.3e-102 341.3 0.1 9.9e-102 341.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med6 PF04934.14 KKA02980.1 - 0.1 12.4 0.5 0.22 11.3 0.4 1.7 1 1 0 1 1 1 0 MED6 mediator sub complex component Lentiviral_Tat PF02998.14 KKA02981.1 - 4.4 7.4 5.5 11 6.2 0.0 3.2 2 0 0 2 2 2 0 Lentiviral Tat protein zf-C2H2 PF00096.26 KKA02982.1 - 0.0014 19.0 2.2 0.0014 19.0 2.2 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKA02982.1 - 0.0045 17.7 16.6 0.013 16.3 1.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKA02982.1 - 0.0079 16.6 0.3 0.0079 16.6 0.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain MRP-L28 PF09812.9 KKA02983.1 - 3e-14 53.5 2.4 3.6e-14 53.2 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 UAA PF08449.11 KKA02984.1 - 1.4e-11 44.2 12.5 7e-08 32.0 4.8 2.9 3 0 0 3 3 3 2 UAA transporter family TPT PF03151.16 KKA02984.1 - 1.9e-11 43.9 20.4 2.9e-06 26.9 12.9 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 KKA02984.1 - 3.7e-05 23.1 9.8 0.0061 15.8 4.1 3.1 3 0 0 3 3 3 2 Purine nucleobase transmembrane transport EamA PF00892.20 KKA02984.1 - 4.2e-05 23.7 32.0 0.011 15.9 4.8 4.0 3 1 0 3 3 3 2 EamA-like transporter family DUF2157 PF09925.9 KKA02984.1 - 0.064 13.0 0.0 0.3 10.9 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) zf-C2H2 PF00096.26 KKA02985.1 - 5.2e-10 39.2 9.5 6e-05 23.3 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA02985.1 - 6.3e-09 35.9 14.8 4.3e-06 26.9 0.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA02985.1 - 9.7e-06 26.0 10.7 0.01 16.6 0.5 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KKA02985.1 - 0.00018 21.3 4.8 0.18 11.7 0.3 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KKA02985.1 - 0.00028 20.8 6.9 0.041 13.9 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKA02985.1 - 0.0026 18.0 7.5 0.032 14.5 0.5 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKA02985.1 - 0.005 17.2 11.3 0.054 13.9 0.9 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KKA02985.1 - 0.0068 17.1 0.4 0.0068 17.1 0.4 3.1 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-piccolo PF05715.13 KKA02985.1 - 0.007 16.5 1.2 0.022 14.9 1.2 1.9 1 0 0 1 1 1 1 Piccolo Zn-finger Zn-ribbon_8 PF09723.10 KKA02985.1 - 0.01 15.9 0.2 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1492 PF07374.11 KKA02985.1 - 0.012 15.8 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Zn_Tnp_IS1595 PF12760.7 KKA02985.1 - 0.034 14.1 1.4 0.055 13.5 1.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FYVE PF01363.21 KKA02985.1 - 0.043 13.9 0.8 0.093 12.9 0.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2_9 PF16293.5 KKA02985.1 - 0.048 13.5 0.9 1.6 8.6 0.1 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Rhodanese_C PF12368.8 KKA02985.1 - 0.049 14.0 0.4 0.081 13.3 0.4 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal zf-AN1 PF01428.16 KKA02985.1 - 0.081 13.1 1.6 13 6.1 0.2 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger DUF4428 PF14471.6 KKA02985.1 - 0.14 12.1 1.3 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) C1_4 PF07975.12 KKA02985.1 - 0.15 12.3 1.0 0.4 10.9 1.0 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain zf_UBZ PF18439.1 KKA02985.1 - 0.16 11.6 0.7 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 KKA02985.1 - 0.33 10.9 2.4 0.61 10.1 2.4 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain GAGA PF09237.11 KKA02985.1 - 0.34 10.8 2.7 4.3 7.2 0.1 2.4 1 1 1 2 2 2 0 GAGA factor zf-BED PF02892.15 KKA02985.1 - 0.52 10.4 6.0 4.7 7.3 0.4 2.6 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.6 KKA02985.1 - 0.61 10.0 3.1 7.7 6.5 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain UPF0020 PF01170.18 KKA02986.1 - 2.7e-13 50.1 0.0 5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 KKA02986.1 - 3.5e-06 26.7 0.0 7.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RRNA methyltransferase AviRa N6_Mtase PF02384.16 KKA02986.1 - 0.0032 16.8 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase IpaB_EvcA PF03278.13 KKA02986.1 - 0.0047 16.7 1.4 0.0096 15.6 1.4 1.4 1 0 0 1 1 1 1 IpaB/EvcA family Methyltransf_31 PF13847.6 KKA02986.1 - 0.086 12.6 0.1 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Amidase PF01425.21 KKA02987.1 - 4e-81 273.3 0.0 5e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Amidase ABC_transp_aux PF09822.9 KKA02987.1 - 0.0043 16.6 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Pkinase PF00069.25 KKA02988.1 - 4e-57 193.6 0.2 7.6e-57 192.7 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA02988.1 - 1e-32 113.5 0.0 1.5e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA02988.1 - 3.4e-05 23.3 0.0 0.00011 21.6 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKA02988.1 - 0.0009 18.1 0.3 0.0019 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KKA02988.1 - 0.048 13.6 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKA02988.1 - 0.14 11.1 6.6 0.02 13.9 2.4 1.7 2 0 0 2 2 2 0 Haspin like kinase domain DUF4393 PF14337.6 KKA02988.1 - 0.22 11.3 7.8 0.033 14.0 2.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4393) DAO PF01266.24 KKA02989.1 - 2.2e-63 215.0 0.0 2.7e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKA02989.1 - 3e-06 27.3 0.1 7.5e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKA02989.1 - 1.5e-05 24.4 0.0 0.0019 17.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KKA02989.1 - 0.0015 18.8 0.1 0.0035 17.6 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain MCRA PF06100.11 KKA02989.1 - 0.0044 15.9 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 KKA02989.1 - 0.0047 16.2 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KKA02989.1 - 0.011 15.7 0.2 0.055 13.4 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KKA02989.1 - 0.027 13.3 0.1 0.082 11.7 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KKA02989.1 - 0.1 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sod_Fe_C PF02777.18 KKA02990.1 - 2.3e-33 114.4 0.8 2.3e-33 114.4 0.8 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKA02990.1 - 1.8e-22 79.6 2.1 3.7e-22 78.6 2.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Flocculin_t3 PF13928.6 KKA02992.1 - 3.4e-14 53.1 17.6 3.4e-14 53.1 17.6 12.1 6 2 1 7 7 7 1 Flocculin type 3 repeat Asp_protease_2 PF13650.6 KKA02992.1 - 4.5 8.0 8.5 5 7.8 0.1 5.0 2 2 1 3 3 3 0 Aspartyl protease DUF4451 PF14616.6 KKA02993.1 - 0.0016 18.6 5.7 0.0028 17.8 5.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zinc_ribbon_12 PF11331.8 KKA02993.1 - 0.053 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain Peptidase_M28 PF04389.17 KKA02995.1 - 2.3e-24 86.2 0.0 4.3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKA02995.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KKA02995.1 - 0.011 14.8 0.0 0.043 12.8 0.0 1.9 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase CENP-B_dimeris PF09026.10 KKA02995.1 - 0.21 12.0 4.1 0.28 11.6 0.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain URO-D PF01208.17 KKA02996.1 - 1.1e-125 419.4 0.0 1.2e-125 419.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) bVLRF1 PF18826.1 KKA02997.1 - 3.8e-56 189.1 0.4 6.4e-56 188.4 0.4 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_4 PF13637.6 KKA02997.1 - 0.00063 20.3 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKA02997.1 - 0.0016 19.0 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKA02997.1 - 0.0019 18.4 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KKA02997.1 - 0.0035 17.7 0.0 0.0082 16.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KKA02997.1 - 0.025 15.1 0.0 0.07 13.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat AKAP95 PF04988.12 KKA02997.1 - 0.75 10.0 8.0 0.061 13.6 1.1 2.6 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) SNF2_N PF00176.23 KKA02998.1 - 1.2e-54 185.3 1.4 2.6e-54 184.3 1.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KKA02998.1 - 3.2e-16 59.8 0.5 3.2e-16 59.8 0.5 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKA02998.1 - 4.2e-15 56.0 0.3 2.8e-14 53.4 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA02998.1 - 7.6e-08 32.3 0.3 2.1e-07 30.9 0.3 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAD_M PF08527.10 KKA02998.1 - 0.38 10.4 0.0 0.38 10.4 0.0 3.2 3 0 0 3 3 3 0 Protein-arginine deiminase (PAD) middle domain FRB_dom PF08771.11 KKA02998.1 - 1 9.8 3.2 3.8 8.0 0.7 3.1 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Alg14 PF08660.11 KKA02999.1 - 3e-42 144.5 0.3 4.2e-42 144.0 0.3 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Dak1 PF02733.17 KKA02999.1 - 0.08 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Dak1 domain TIM PF00121.18 KKA03000.1 - 7.7e-86 287.4 0.1 8.6e-86 287.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase tRNA-synt_2 PF00152.20 KKA03001.1 - 4.3e-80 269.1 2.0 7.5e-80 268.3 2.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKA03001.1 - 1.1e-11 44.6 0.1 2.4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKA03001.1 - 1.3e-06 28.1 0.1 0.0042 16.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GCR1_C PF12550.8 KKA03001.1 - 0.29 11.5 3.0 0.48 10.8 0.2 2.6 3 0 0 3 3 3 0 Transcriptional activator of glycolytic enzymes Spa1_C PF18218.1 KKA03001.1 - 1.5 9.3 4.0 47 4.5 1.8 2.6 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain FtsJ PF01728.19 KKA03002.1 - 2.1e-65 220.1 0.0 2.9e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP16 PF06460.12 KKA03002.1 - 0.023 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 Ribosomal_S10 PF00338.22 KKA03003.1 - 5.3e-12 45.8 0.0 1.6e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Flocculin_t3 PF13928.6 KKA03004.1 - 4.9e-16 59.0 21.7 4.9e-16 59.0 21.7 8.0 4 2 1 5 5 5 1 Flocculin type 3 repeat Flocculin_t3 PF13928.6 KKA03005.1 - 2.2e-15 56.8 19.3 2.2e-15 56.8 19.3 7.5 3 2 4 7 7 7 1 Flocculin type 3 repeat SGL PF08450.12 KKA03006.1 - 5.7e-42 144.0 0.2 7.6e-42 143.6 0.2 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region ECH_2 PF16113.5 KKA03007.1 - 4.9e-25 88.7 0.1 3.1e-23 82.8 0.0 2.4 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KKA03007.1 - 1.8e-08 34.0 0.0 4.7e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase SPOUT_MTase PF02590.17 KKA03007.1 - 0.28 11.1 2.2 0.89 9.5 0.2 2.7 1 1 2 3 3 3 0 Predicted SPOUT methyltransferase UCH PF00443.29 KKA03008.1 - 6.5e-40 137.2 1.0 6.5e-40 137.2 1.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKA03008.1 - 3.6e-19 68.9 18.2 2.7e-18 66.1 5.6 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KKA03008.1 - 5.7e-12 45.3 0.0 1.7e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KKA03008.1 - 6.1e-12 45.8 0.4 6.1e-12 45.8 0.4 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KKA03008.1 - 7.3e-11 41.7 7.6 1.1e-10 41.1 2.6 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UBA_4 PF14555.6 KKA03008.1 - 0.00052 19.8 0.0 0.25 11.2 0.1 2.5 2 0 0 2 2 2 2 UBA-like domain DUF5023 PF16426.5 KKA03008.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) Coiled PF05710.12 KKA03008.1 - 9.5 7.1 6.9 4.2 8.2 0.5 3.1 2 1 1 3 3 3 0 Coiled coil Wtap PF17098.5 KKA03009.1 - 1.7e-06 28.0 11.8 1.9e-05 24.7 11.8 2.4 1 1 0 1 1 1 1 WTAP/Mum2p family SlyX PF04102.12 KKA03009.1 - 0.64 10.7 4.3 2.1 9.0 0.4 3.3 3 0 0 3 3 3 0 SlyX DASH_Spc19 PF08287.11 KKA03009.1 - 1.3 8.9 12.7 3.8 7.4 2.9 3.2 2 1 0 2 2 2 0 Spc19 DivIC PF04977.15 KKA03009.1 - 5.9 6.7 10.9 16 5.4 1.3 3.8 3 0 0 3 3 3 0 Septum formation initiator HSBP1 PF06825.12 KKA03009.1 - 6 6.8 7.6 0.78 9.6 0.6 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 MatE PF01554.18 KKA03010.1 - 9.5e-53 178.1 24.9 5.2e-29 101.0 7.5 2.8 3 0 0 3 3 3 2 MatE Fungal_trans_2 PF11951.8 KKA03011.1 - 1.4e-14 53.7 2.6 2.6e-14 52.8 2.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA03011.1 - 0.0003 20.9 9.9 0.00069 19.7 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.12 KKA03012.1 - 0.0051 17.2 0.5 0.043 14.2 0.5 2.3 1 1 0 1 1 1 1 PRP1 splicing factor, N-terminal Pkinase PF00069.25 KKA03014.1 - 9.3e-37 126.8 0.1 2.5e-36 125.4 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03014.1 - 2.4e-23 82.7 0.0 1.8e-22 79.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA03014.1 - 0.0065 15.8 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKA03014.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ald_deCOase PF11266.8 KKA03014.1 - 0.019 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase RIO1 PF01163.22 KKA03014.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.3 3 0 0 3 3 3 0 RIO1 family FoP_duplication PF13865.6 KKA03014.1 - 0.27 11.8 0.1 0.27 11.8 0.1 2.6 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 ORC2 PF04084.14 KKA03015.1 - 1.4e-44 152.4 0.1 1.7e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TFIIS_C PF01096.18 KKA03017.1 - 4e-20 71.4 2.3 4e-20 71.4 2.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKA03017.1 - 6.9e-11 41.8 4.2 4.3e-10 39.3 1.8 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KKA03017.1 - 0.0016 18.3 5.5 0.15 12.1 0.7 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Elf1 PF05129.13 KKA03017.1 - 0.0084 16.1 3.6 0.22 11.6 0.1 2.3 2 1 0 2 2 2 1 Transcription elongation factor Elf1 like C1_4 PF07975.12 KKA03017.1 - 0.024 14.8 5.2 0.073 13.3 0.4 2.5 2 2 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 KKA03017.1 - 0.18 12.0 0.4 0.18 12.0 0.4 2.7 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 KKA03017.1 - 0.23 10.9 0.1 0.23 10.9 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain DUF2387 PF09526.10 KKA03017.1 - 0.3 11.3 3.4 11 6.2 0.2 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 KKA03017.1 - 0.84 9.7 8.0 0.42 10.7 0.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KKA03017.1 - 0.86 9.6 12.3 1.6 8.7 0.7 3.7 3 1 1 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KKA03017.1 - 1 8.9 9.6 2.3 7.8 2.0 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 KKA03017.1 - 4.6 7.3 7.7 1.3 9.0 0.2 2.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Coprogen_oxidas PF01218.18 KKA03018.1 - 1.3e-134 447.6 0.2 1.5e-134 447.4 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-C2H2 PF00096.26 KKA03019.1 - 0.00046 20.5 16.6 0.0085 16.5 2.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA03019.1 - 0.0016 18.8 2.1 0.0016 18.8 2.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 KKA03019.1 - 0.014 15.1 4.6 0.78 9.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KKA03019.1 - 0.024 15.4 1.4 0.024 15.4 1.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1752 PF08550.10 KKA03020.1 - 1.1e-08 34.8 2.5 7.2e-07 28.9 0.1 2.7 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1752) ADH_zinc_N PF00107.26 KKA03022.1 - 4.6e-23 81.6 0.0 1.9e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKA03022.1 - 7e-17 62.7 0.0 1.4e-16 61.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKA03022.1 - 5.6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KKA03022.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase QueH PF02677.14 KKA03022.1 - 0.049 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH TrkA_N PF02254.18 KKA03022.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain tRNA-synt_2b PF00587.25 KKA03024.1 - 1e-36 126.6 0.2 1.8e-36 125.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKA03024.1 - 1.3e-20 73.7 8.6 1.3e-20 73.7 8.6 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.15 KKA03024.1 - 0.047 12.6 0.3 0.096 11.6 0.3 1.5 1 0 0 1 1 1 0 Cytochrome c552 Acetyltransf_18 PF18014.1 KKA03024.1 - 0.091 12.6 0.1 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Occludin_ELL PF07303.13 KKA03024.1 - 0.77 10.5 6.0 0.3 11.8 2.6 2.0 2 0 0 2 2 2 0 Occludin homology domain CHD5 PF04420.14 KKA03024.1 - 1.7 8.5 4.4 0.94 9.3 0.7 2.1 1 1 0 2 2 2 0 CHD5-like protein DEAD PF00270.29 KKA03025.1 - 5.9e-38 130.4 1.9 5.9e-38 130.4 1.9 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA03025.1 - 1.6e-31 109.0 0.5 1.6e-31 109.0 0.5 3.0 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA03025.1 - 3.4e-07 30.4 0.3 3.4e-07 30.4 0.3 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PTP2 PF17022.5 KKA03025.1 - 0.0035 17.0 5.2 0.0065 16.1 5.2 1.4 1 0 0 1 1 1 1 Polar tube protein 2 from Microsporidia AAA_19 PF13245.6 KKA03025.1 - 0.033 14.5 0.0 0.063 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain MCR_alpha_N PF02745.15 KKA03025.1 - 0.042 13.2 0.6 0.093 12.1 0.4 1.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain CobA_CobO_BtuR PF02572.15 KKA03025.1 - 0.094 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP LRR_2 PF07723.13 KKA03026.1 - 0.0031 18.1 0.2 7.9 7.3 0.0 3.6 2 0 0 2 2 2 2 Leucine Rich Repeat Glyco_hydro_59M PF17387.2 KKA03026.1 - 0.014 15.6 0.1 0.069 13.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 central domain CRIC_ras_sig PF10534.9 KKA03026.1 - 0.021 15.0 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras GCV_T PF01571.21 KKA03027.1 - 1.3e-80 270.5 0.0 1.8e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KKA03027.1 - 1.2e-13 50.7 0.0 2.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain S-layer PF07752.11 KKA03027.1 - 0.0037 16.4 0.4 0.0062 15.6 0.4 1.3 1 0 0 1 1 1 1 S-layer protein Alginate_lyase2 PF08787.11 KKA03027.1 - 0.048 13.5 0.1 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Alginate lyase MFS_1 PF07690.16 KKA03028.1 - 6.9e-42 143.6 11.4 6.9e-42 143.6 11.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA03028.1 - 3e-11 42.8 0.9 3e-11 42.8 0.9 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KKA03028.1 - 0.0004 19.8 0.2 0.0004 19.8 0.2 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KKA03028.1 - 0.028 12.7 16.7 0.012 13.9 4.8 4.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family YMF19 PF02326.15 KKA03028.1 - 0.19 12.5 0.1 0.19 12.5 0.1 3.6 5 0 0 5 5 5 0 Plant ATP synthase F0 DUF5592 PF17332.2 KKA03028.1 - 0.24 12.0 7.8 2.7 8.6 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5592) Acyltransferase PF01553.21 KKA03029.1 - 1.3e-28 99.3 0.0 2.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KKA03029.1 - 2.5e-10 40.3 0.1 5e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus YrvL PF14184.6 KKA03029.1 - 0.05 13.7 4.4 0.11 12.6 4.4 1.6 1 0 0 1 1 1 0 Regulatory protein YrvL AMP-binding PF00501.28 KKA03030.1 - 2.7e-55 187.7 0.0 3.3e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKA03030.1 - 0.0031 18.5 0.0 0.0065 17.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fig1 PF12351.8 KKA03031.1 - 1.3e-13 51.3 4.1 1.3e-13 51.3 4.1 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 FtsX PF02687.21 KKA03031.1 - 3 8.4 8.7 0.18 12.3 0.8 2.6 3 0 0 3 3 3 0 FtsX-like permease family Sigma_reg_N PF13800.6 KKA03031.1 - 3.2 8.1 7.1 0.61 10.4 0.4 3.0 3 1 0 3 3 3 0 Sigma factor regulator N-terminal DUF202 PF02656.15 KKA03031.1 - 9 6.8 7.9 20 5.7 4.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ATP-synt PF00231.19 KKA03032.1 - 1.4e-69 234.9 8.9 1.6e-69 234.7 8.9 1.0 1 0 0 1 1 1 1 ATP synthase IPK PF03770.16 KKA03033.1 - 1.2e-42 146.0 0.6 2.7e-42 144.9 0.6 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase PP2C PF00481.21 KKA03035.1 - 6.4e-29 101.4 0.0 5.4e-27 95.1 0.0 3.5 1 1 0 2 2 2 1 Protein phosphatase 2C Peptidase_M13 PF01431.21 KKA03036.1 - 0.017 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M13 DEAD PF00270.29 KKA03037.1 - 2.5e-38 131.6 1.5 4.8e-38 130.7 1.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA03037.1 - 1.4e-18 67.2 8.1 3.3e-18 66.0 1.3 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA03037.1 - 5.6e-10 39.5 2.4 5.6e-10 39.5 2.4 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKA03037.1 - 3.1e-05 23.4 2.7 3.1e-05 23.4 2.7 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KKA03037.1 - 0.0026 17.7 0.2 0.055 13.5 0.0 2.7 1 1 1 2 2 2 1 Flavivirus DEAD domain LAP1C PF05609.12 KKA03037.1 - 2 7.4 15.2 3.2 6.7 15.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LRR_RI_capping PF18779.1 KKA03039.1 - 0.014 15.1 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat tRNA_NucTran2_2 PF13735.6 KKA03039.1 - 0.053 13.5 5.1 0.045 13.7 1.3 2.8 3 0 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative zf-met PF12874.7 KKA03040.1 - 5.7e-06 26.5 2.9 1.1e-05 25.7 2.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKA03040.1 - 0.0056 17.0 0.5 0.0056 17.0 0.5 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KKA03040.1 - 0.014 15.1 0.5 0.028 14.2 0.5 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_jaz PF12171.8 KKA03040.1 - 0.25 11.7 4.2 0.88 9.9 4.2 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.16 KKA03041.1 - 3e-16 59.3 28.6 2.7e-15 56.1 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Saf_2TM PF18303.1 KKA03041.1 - 0.044 13.4 1.1 0.14 11.7 0.0 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Chordopox_G3 PF06129.12 KKA03041.1 - 0.053 14.2 1.3 1.2 9.8 0.5 2.8 2 0 0 2 2 2 0 Chordopoxvirus G3 protein YqzM PF14141.6 KKA03041.1 - 0.22 11.6 3.2 36 4.5 0.3 3.8 3 0 0 3 3 3 0 YqzM-like protein Phage_GP20 PF06810.11 KKA03041.1 - 0.33 10.7 4.2 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 RRM_1 PF00076.22 KKA03042.1 - 1.7e-09 37.4 0.0 4.4e-07 29.6 0.0 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Imm70 PF15601.6 KKA03043.1 - 0.036 13.6 2.4 0.11 12.0 2.4 1.8 1 0 0 1 1 1 0 Immunity protein 70 CAF1 PF04857.20 KKA03044.1 - 1.7e-11 43.9 3.2 3.3e-05 23.2 0.7 2.2 1 1 0 2 2 2 2 CAF1 family ribonuclease Sacchrp_dh_C PF16653.5 KKA03045.1 - 1.2e-93 314.0 0.0 1.6e-93 313.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KKA03045.1 - 1.2e-20 74.1 0.0 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KKA03045.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KKA03045.1 - 1.7e-05 24.8 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KKA03045.1 - 0.15 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mso1_Sec1_bdg PF14475.6 KKA03046.1 - 2e-11 43.3 1.4 6.3e-11 41.7 1.4 1.9 1 1 0 1 1 1 1 Sec1-binding region of Mso1 UQ_con PF00179.26 KKA03047.1 - 1.3e-41 141.5 0.1 2e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KKA03047.1 - 2.3e-06 27.3 0.1 4.6e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Calsarcin PF05556.11 KKA03047.1 - 0.0044 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) E1_dh PF00676.20 KKA03047.1 - 0.063 12.2 0.4 0.74 8.7 0.2 2.0 2 0 0 2 2 2 0 Dehydrogenase E1 component RWD PF05773.22 KKA03047.1 - 0.085 13.1 1.5 0.13 12.6 0.0 2.0 2 1 0 2 2 2 0 RWD domain CDC50 PF03381.15 KKA03048.1 - 2.6e-87 292.9 1.8 3.3e-87 292.6 1.8 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family COX4 PF02936.14 KKA03048.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV NDUF_B5 PF09781.9 KKA03048.1 - 0.078 12.6 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Not1 PF04054.15 KKA03049.1 - 2.4e-76 257.1 8.0 7.6e-76 255.4 8.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KKA03049.1 - 1.5e-41 142.3 9.1 1.5e-41 142.3 9.1 3.2 3 1 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KKA03049.1 - 1.9e-26 92.7 8.1 1.9e-26 92.7 8.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KKA03049.1 - 2e-08 33.6 4.2 3.3e-08 32.9 1.5 2.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Pkinase PF00069.25 KKA03050.1 - 5.1e-75 252.2 0.8 2.4e-74 250.0 0.8 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03050.1 - 6.9e-36 123.9 0.3 2.5e-24 86.0 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKA03050.1 - 0.00045 19.6 1.4 0.096 12.0 0.2 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KKA03050.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MutS_V PF00488.21 KKA03051.1 - 1.2e-38 133.1 0.0 2.2e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKA03051.1 - 4.4e-13 49.9 2.7 2.1e-12 47.7 0.1 2.4 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KKA03051.1 - 2.2e-08 34.3 1.7 5e-08 33.2 0.2 2.5 3 0 0 3 3 3 1 MutS domain I AAA_14 PF13173.6 KKA03051.1 - 0.00016 21.7 0.7 0.00089 19.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKA03051.1 - 0.00026 21.4 0.0 0.00087 19.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KKA03051.1 - 0.073 12.9 5.9 0.13 12.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KKA03051.1 - 0.081 13.4 1.0 0.49 10.9 0.0 2.9 4 0 0 4 4 4 0 ABC transporter Trm112p PF03966.16 KKA03052.1 - 5.9e-16 58.8 0.5 7.3e-16 58.5 0.5 1.1 1 0 0 1 1 1 1 Trm112p-like protein PAT1 PF09770.9 KKA03053.1 - 1.3e-41 142.9 42.8 6.3e-32 110.8 2.5 2.8 1 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 NSP2_assoc PF14758.6 KKA03054.1 - 0.026 14.9 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein PQ-loop PF04193.14 KKA03055.1 - 4.7e-07 29.5 10.7 5.9e-06 26.0 0.5 3.9 3 2 1 4 4 4 2 PQ loop repeat SK_channel PF03530.14 KKA03055.1 - 5.4 7.0 10.7 0.36 10.8 2.9 2.5 2 1 0 2 2 2 0 Calcium-activated SK potassium channel Glucosamine_iso PF01182.20 KKA03056.1 - 1e-48 166.2 0.0 1.5e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Metallophos PF00149.28 KKA03057.1 - 5.2e-31 108.7 0.4 2.4e-30 106.6 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase YL1 PF05764.13 KKA03057.1 - 0.014 15.5 13.9 0.014 15.5 13.9 1.6 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 KKA03057.1 - 0.072 11.4 12.4 0.1 10.9 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 KKA03057.1 - 0.58 8.2 6.1 0.84 7.6 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KKA03057.1 - 1 7.5 16.5 1.9 6.6 16.5 1.3 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 KKA03057.1 - 4 7.1 14.1 8.7 6.0 14.1 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Pkinase PF00069.25 KKA03058.1 - 3.4e-64 216.7 0.5 9.1e-64 215.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03058.1 - 6.8e-33 114.0 0.4 6.6e-25 87.9 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKA03058.1 - 3.3e-06 26.6 0.0 2.7e-05 23.6 0.0 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KKA03058.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1836 PF08876.11 KKA03058.1 - 1.3 9.1 12.4 0.8 9.8 1.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1836) WD40 PF00400.32 KKA03059.1 - 4e-61 201.5 38.5 8.4e-12 45.4 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03059.1 - 6.8e-19 68.0 7.2 0.0001 22.5 0.1 5.5 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KKA03059.1 - 8.6e-11 42.2 0.2 1.9e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 KKA03059.1 - 1.7e-09 37.9 0.2 0.00027 20.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKA03059.1 - 3.7e-05 22.6 3.7 0.68 8.5 0.4 4.8 3 1 1 5 5 5 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKA03059.1 - 0.00023 19.8 0.1 0.2 10.1 0.1 3.0 3 1 1 4 4 4 3 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KKA03059.1 - 0.00023 20.3 0.0 0.27 10.2 0.0 3.5 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KKA03059.1 - 0.0038 16.6 0.0 0.97 8.7 0.0 3.6 3 2 1 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KKA03059.1 - 0.0043 15.8 5.5 0.049 12.4 0.2 3.4 2 1 0 3 3 3 1 Nup133 N terminal like zf-C2H2_aberr PF17017.5 KKA03059.1 - 0.023 14.8 0.1 0.047 13.8 0.1 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger SVA PF05326.11 KKA03059.1 - 0.032 14.2 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) IKI3 PF04762.12 KKA03059.1 - 0.073 11.1 0.0 0.14 10.1 0.0 1.4 1 0 0 1 1 1 0 IKI3 family PKD PF00801.20 KKA03059.1 - 0.13 12.1 0.4 19 5.2 0.1 3.2 3 0 0 3 3 3 0 PKD domain Img2 PF05046.14 KKA03060.1 - 0.00017 21.8 0.1 0.00042 20.5 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Glyco_transf_22 PF03901.17 KKA03061.1 - 2.4e-17 63.3 25.9 3.3e-17 62.8 25.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pro_isomerase PF00160.21 KKA03062.1 - 6.9e-24 84.9 0.5 1.1e-23 84.2 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF362 PF04015.12 KKA03062.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) EamA PF00892.20 KKA03063.1 - 1.1e-22 80.7 28.3 1.4e-12 47.9 5.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family YwiC PF14256.6 KKA03063.1 - 0.12 12.7 0.5 0.6 10.4 0.2 2.1 1 1 1 2 2 2 0 YwiC-like protein TspO_MBR PF03073.15 KKA03063.1 - 0.38 10.8 9.1 0.044 13.8 2.3 2.6 2 1 1 3 3 3 0 TspO/MBR family P34-Arc PF04045.14 KKA03064.1 - 1.3e-73 247.7 3.6 1.7e-73 247.3 3.6 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc tRNA-synt_1d PF00750.19 KKA03065.1 - 1.1e-114 383.1 6.5 1.4e-114 382.7 6.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KKA03065.1 - 6.6e-29 100.5 0.0 2e-28 99.0 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KKA03065.1 - 3.5e-06 27.5 0.0 9.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF1765 PF08578.10 KKA03066.1 - 0.0058 17.1 0.3 3.5 8.1 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1765) DUF866 PF05907.13 KKA03067.1 - 8.1e-21 74.6 8.9 2.7e-20 72.9 8.9 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.6 KKA03067.1 - 0.34 10.9 4.1 0.72 9.9 4.0 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c TF_Zn_Ribbon PF08271.12 KKA03067.1 - 0.77 9.3 3.2 20 4.8 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding Flocculin_t3 PF13928.6 KKA03068.1 - 5.2e-06 26.9 56.9 7.5e-05 23.2 24.0 14.0 9 7 1 10 10 10 3 Flocculin type 3 repeat Ivy PF08816.11 KKA03068.1 - 0.015 15.5 1.8 5.6 7.2 0.1 2.9 3 0 0 3 3 3 0 Inhibitor of vertebrate lysozyme (Ivy) zf_PR_Knuckle PF18445.1 KKA03068.1 - 0.44 10.4 5.1 2.6 8.0 0.2 3.2 3 0 0 3 3 3 0 PR zinc knuckle motif zf-tcix PF14952.6 KKA03068.1 - 3.7 7.2 5.1 7.3 6.3 0.4 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding SH3_9 PF14604.6 KKA03069.1 - 1.9e-15 56.4 0.5 1.9e-15 56.4 0.5 2.1 3 0 0 3 3 3 1 Variant SH3 domain Cofilin_ADF PF00241.20 KKA03069.1 - 3.3e-15 56.0 0.6 3.3e-15 56.0 0.6 2.4 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 KKA03069.1 - 1e-14 53.8 2.7 2.4e-14 52.7 0.6 2.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KKA03069.1 - 8.3e-10 38.2 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-LYAR PF08790.11 KKA03070.1 - 1e-10 41.3 9.0 2.7e-10 40.0 9.0 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KKA03070.1 - 0.29 10.8 6.5 2.3 7.9 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 KKA03070.1 - 0.38 11.7 9.7 0.61 11.1 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Fer4_9 PF13187.6 KKA03070.1 - 0.46 10.7 6.7 1.2 9.3 6.7 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain HHH_9 PF17674.1 KKA03070.1 - 3.9 8.5 8.7 0.94 10.4 2.7 2.2 1 1 1 2 2 2 0 HHH domain Csm1 PF12539.8 KKA03071.1 - 0.017 15.7 0.3 0.29 11.8 0.3 2.4 1 1 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 Cnn_1N PF07989.11 KKA03071.1 - 0.039 14.1 2.9 0.083 13.1 2.9 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF1758 PF05585.12 KKA03071.1 - 0.047 13.5 0.1 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DivIC PF04977.15 KKA03071.1 - 0.074 12.8 1.8 0.14 12.0 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator UbiA PF01040.18 KKA03073.1 - 1e-40 139.6 8.8 1.5e-40 139.1 8.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family NuA4 PF09340.10 KKA03074.1 - 6e-07 29.3 19.2 4.3e-05 23.3 10.1 3.8 1 1 1 2 2 2 2 Histone acetyltransferase subunit NuA4 STPPase_N PF16891.5 KKA03074.1 - 0.066 13.7 0.9 2.4 8.7 0.3 2.5 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF4844 PF16133.5 KKA03074.1 - 0.067 13.7 7.2 0.062 13.9 1.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4844) Glyco_hydro_108 PF05838.12 KKA03074.1 - 0.11 13.0 0.2 0.33 11.5 0.2 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase 108 Anti-adapt_IraP PF10796.9 KKA03074.1 - 2.7 8.6 7.7 18 6.0 0.6 3.1 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein Sugar_tr PF00083.24 KKA03075.1 - 1.9e-23 83.1 16.4 1e-17 64.2 3.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKA03075.1 - 1.1e-13 50.9 44.4 6.9e-11 41.7 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKA03075.1 - 0.00028 19.6 23.8 0.0064 15.1 0.4 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein WD40 PF00400.32 KKA03076.1 - 2.4e-47 157.9 16.5 3.8e-07 30.7 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03076.1 - 3.8e-16 59.2 0.5 0.02 15.2 0.0 6.2 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKA03076.1 - 6.8e-08 31.8 0.3 0.009 15.0 0.0 3.9 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Tup_N PF08581.10 KKA03076.1 - 8e-07 29.3 13.6 8e-07 29.3 13.6 3.6 2 1 1 3 3 3 1 Tup N-terminal Nup160 PF11715.8 KKA03076.1 - 0.00061 18.6 3.3 0.0075 15.0 0.2 3.4 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KKA03076.1 - 0.00096 18.6 0.2 0.061 12.6 0.0 3.0 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KKA03076.1 - 0.005 16.2 5.6 1 8.6 0.1 3.9 4 1 1 5 5 5 2 WD40-like domain Thioredoxin PF00085.20 KKA03077.1 - 9.8e-27 93.0 0.1 1.3e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKA03077.1 - 6.3e-07 29.8 0.1 2.1e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KKA03077.1 - 8.3e-07 28.8 0.1 2.8e-06 27.1 0.1 1.6 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 KKA03077.1 - 9.5e-06 25.5 0.1 1.1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KKA03077.1 - 0.00063 19.5 0.1 0.00076 19.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKA03077.1 - 0.00065 20.0 0.1 0.0067 16.7 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KKA03077.1 - 0.0017 18.5 0.1 0.0027 17.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KKA03077.1 - 0.0022 17.4 0.1 0.0029 17.0 0.0 1.2 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Cyclin_N PF00134.23 KKA03078.1 - 1.1e-38 131.9 0.1 3e-37 127.2 0.1 2.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKA03078.1 - 1.9e-30 105.4 0.4 5.8e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Evr1_Alr PF04777.13 KKA03078.1 - 0.075 13.5 0.3 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 Erv1 / Alr family Cyclin_N PF00134.23 KKA03079.1 - 3.8e-33 113.9 2.2 9.3e-33 112.7 2.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain GARS_A PF01071.19 KKA03080.1 - 5.4e-80 267.8 0.0 9.2e-80 267.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KKA03080.1 - 1.5e-30 106.4 0.0 3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KKA03080.1 - 4.5e-27 94.7 0.0 1.6e-26 92.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KKA03080.1 - 2.8e-24 85.2 0.0 6.5e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KKA03080.1 - 5e-15 55.9 3.0 8.4e-15 55.2 2.1 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KKA03080.1 - 2.1e-05 24.6 0.1 6.8e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KKA03080.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 KKA03080.1 - 0.042 13.4 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Mito_carr PF00153.27 KKA03081.1 - 2.4e-31 107.5 2.1 3.9e-13 49.1 0.0 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KKA03082.1 - 4.7e-08 32.9 1.1 0.016 15.1 0.3 3.9 4 1 0 4 4 4 3 Mitochondrial carrier protein LSM PF01423.22 KKA03083.1 - 3.3e-18 65.1 0.1 3.3e-18 65.1 0.1 2.2 2 1 1 3 3 3 1 LSM domain Glyco_transf_8 PF01501.20 KKA03083.1 - 0.082 12.4 5.3 0.23 11.0 3.0 2.0 1 1 0 2 2 2 0 Glycosyl transferase family 8 Hexokinase_2 PF03727.16 KKA03085.1 - 7e-78 261.4 0.0 9.1e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKA03085.1 - 2e-63 213.9 0.0 2.8e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase A_deamin PF02137.18 KKA03086.1 - 6e-31 108.1 0.4 7.5e-31 107.8 0.4 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Scm3 PF10384.9 KKA03086.1 - 0.078 12.7 2.7 4.6 7.1 0.2 3.4 3 0 0 3 3 3 0 Centromere protein Scm3 EamA PF00892.20 KKA03087.1 - 2.6e-09 37.4 27.0 7.3e-06 26.2 8.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family TRAP-gamma PF07074.12 KKA03087.1 - 0.032 13.8 0.3 0.032 13.8 0.3 2.4 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) OAD_gamma PF04277.13 KKA03087.1 - 0.2 12.3 2.6 0.57 10.8 0.2 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ost5 PF05251.12 KKA03087.1 - 0.31 11.3 0.0 0.31 11.3 0.0 4.0 5 1 0 5 5 5 0 Oligosaccharyltransferase subunit 5 PHO4 PF01384.20 KKA03087.1 - 0.78 8.7 21.2 0.095 11.7 3.9 3.0 1 1 2 3 3 3 0 Phosphate transporter family PMSR PF01625.21 KKA03089.1 - 5.2e-51 172.8 0.9 6.4e-51 172.5 0.9 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase COX4 PF02936.14 KKA03090.1 - 2e-08 34.3 0.1 3.7e-08 33.5 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV Neurochondrin PF05536.11 KKA03091.1 - 0.00027 19.5 0.1 0.00047 18.7 0.1 1.3 1 0 0 1 1 1 1 Neurochondrin Med13_N PF11597.8 KKA03092.1 - 5.5e-60 203.4 9.0 1.1e-59 202.4 9.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 KKA03092.1 - 0.00014 21.2 0.6 0.00014 21.2 0.6 4.0 4 1 1 5 5 5 1 Mediator complex subunit 13 C-terminal domain TAFII28 PF04719.14 KKA03093.1 - 8.8e-07 28.9 0.7 1.5e-05 25.0 0.2 2.7 3 0 0 3 3 3 1 hTAFII28-like protein conserved region Peptidase_M41 PF01434.18 KKA03093.1 - 0.25 11.2 4.7 0.2 11.4 0.4 2.3 1 1 1 2 2 2 0 Peptidase family M41 LCM PF04072.14 KKA03094.1 - 2.7e-19 69.9 0.0 3.8e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase FlaC_arch PF05377.11 KKA03094.1 - 0.14 12.6 2.2 1.5 9.2 0.7 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AdoHcyase PF05221.17 KKA03095.1 - 1.6e-130 434.6 0.0 6.4e-74 248.8 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KKA03095.1 - 3.3e-83 277.6 1.0 5.2e-83 276.9 1.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKA03095.1 - 1e-06 28.2 0.1 1.9e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KKA03095.1 - 0.0034 17.0 0.1 0.0067 16.0 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KKA03095.1 - 0.0039 17.4 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GATA PF00320.27 KKA03096.1 - 7.7e-15 54.2 5.5 1.5e-14 53.3 5.5 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KKA03096.1 - 0.066 12.7 0.4 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_I PF00867.18 KKA03097.1 - 2.1e-11 44.0 0.0 7.6e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KKA03097.1 - 0.012 16.1 0.2 0.032 14.7 0.2 1.7 1 0 0 1 1 1 0 XPG N-terminal domain Skp1 PF01466.19 KKA03097.1 - 0.32 11.1 1.7 12 6.0 0.1 3.2 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Pribosyltran PF00156.27 KKA03098.1 - 2.7e-16 59.5 0.0 3.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKA03098.1 - 0.00023 20.7 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DOT1 PF08123.13 KKA03099.1 - 9.8e-47 159.1 5.6 5.9e-46 156.6 2.0 2.9 1 1 1 2 2 2 1 Histone methylation protein DOT1 YpM PF09144.10 KKA03099.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.4 3 0 0 3 3 3 0 Yersinia pseudo-tuberculosis mitogen MYO10_CC PF16735.5 KKA03099.1 - 2.4 8.3 6.5 0.18 11.9 0.3 2.4 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain UDG PF03167.19 KKA03100.1 - 5.7e-19 68.6 0.1 4e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF2258 PF10015.9 KKA03100.1 - 3.9 7.7 8.7 1.2 9.4 1.4 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) DHHC PF01529.20 KKA03101.1 - 1.7e-20 73.5 14.7 1.7e-20 73.5 14.7 2.8 2 2 0 2 2 2 1 DHHC palmitoyltransferase A_deaminase PF00962.22 KKA03102.1 - 2.4e-125 418.2 0.2 3.6e-125 417.7 0.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1819 PF08849.11 KKA03103.1 - 0.012 15.5 1.0 0.018 14.9 1.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) SPA PF08616.10 KKA03103.1 - 0.065 13.2 0.6 0.63 10.0 0.2 2.5 1 1 1 2 2 2 0 Stabilization of polarity axis HECT PF00632.25 KKA03104.1 - 1e-88 297.8 1.7 1.4e-88 297.4 0.4 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 KKA03105.1 - 1e-34 120.2 1.2 1.8e-34 119.3 1.2 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KKA03105.1 - 2e-20 73.5 5.6 1.9e-07 30.8 0.7 3.9 4 0 0 4 4 4 3 Domain of Unknown Function (DUF908) Ndc1_Nup PF09531.10 KKA03106.1 - 7.3e-37 127.3 27.7 2.3e-31 109.2 1.7 2.3 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Phospholamban PF04272.14 KKA03106.1 - 3.6 7.1 11.6 2.4 7.7 0.9 3.4 3 0 0 3 3 3 0 Phospholamban Na_H_Exchanger PF00999.21 KKA03107.1 - 5.6e-68 229.5 27.8 5.6e-68 229.5 27.8 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 KKA03107.1 - 0.13 12.2 1.9 0.17 11.8 0.6 1.8 2 0 0 2 2 2 0 Myc target protein 1 Bap31 PF05529.12 KKA03108.1 - 2.8e-18 66.1 6.4 4.7e-18 65.4 6.4 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF1980 PF09323.10 KKA03108.1 - 0.0058 16.6 4.0 0.0077 16.2 3.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) EF-1_beta_acid PF10587.9 KKA03108.1 - 0.069 13.6 1.3 0.069 13.6 1.3 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region T2SSG PF08334.11 KKA03108.1 - 0.07 13.2 0.1 2.7 8.1 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G Guanylate_kin PF00625.21 KKA03109.1 - 2.9e-67 225.9 0.0 3.3e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KKA03109.1 - 5.7e-07 30.1 0.0 9.8e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKA03109.1 - 4.8e-05 23.7 0.0 0.0002 21.6 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KKA03109.1 - 0.00011 22.4 0.0 0.00039 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKA03109.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KKA03109.1 - 0.00018 21.6 0.1 0.00063 19.8 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKA03109.1 - 0.00035 20.9 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KKA03109.1 - 0.00096 19.4 0.0 0.0031 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KKA03109.1 - 0.001 18.9 0.1 0.009 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKA03109.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KKA03109.1 - 0.0016 19.0 0.0 0.0024 18.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 KKA03109.1 - 0.0034 17.4 0.0 0.0067 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKA03109.1 - 0.0036 17.7 0.1 0.008 16.6 0.0 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KKA03109.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.6 1 1 1 2 2 2 1 KAP family P-loop domain AAA_7 PF12775.7 KKA03109.1 - 0.0041 16.7 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KKA03109.1 - 0.0045 16.9 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KKA03109.1 - 0.0055 15.8 0.1 0.017 14.2 0.0 1.8 1 1 1 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KKA03109.1 - 0.018 14.8 1.0 0.033 13.9 0.3 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KKA03109.1 - 0.02 14.9 0.0 0.054 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KKA03109.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KKA03109.1 - 0.023 14.6 0.1 0.067 13.1 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KKA03109.1 - 0.024 14.6 0.0 0.037 13.9 0.0 1.5 1 1 0 1 1 1 0 NTPase Rad17 PF03215.15 KKA03109.1 - 0.028 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 KKA03109.1 - 0.064 12.9 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KKA03109.1 - 0.072 13.4 0.1 0.46 10.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KKA03109.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin Viral_helicase1 PF01443.18 KKA03109.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KKA03109.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KKA03109.1 - 0.16 11.5 0.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKA03109.1 - 0.17 11.9 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HIG_1_N PF04588.13 KKA03110.1 - 8.5e-16 57.9 0.1 1.3e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DNA_topoisoIV PF00521.20 KKA03110.1 - 0.026 13.4 5.5 0.027 13.4 5.5 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A AAA_23 PF13476.6 KKA03110.1 - 0.036 14.6 7.4 0.034 14.6 7.4 1.2 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 KKA03110.1 - 0.073 11.7 8.1 0.077 11.6 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2730 PF10805.8 KKA03110.1 - 0.075 13.1 4.5 0.16 12.1 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Atg14 PF10186.9 KKA03110.1 - 0.23 10.5 8.2 0.26 10.3 8.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 O-antigen_lig PF13425.6 KKA03110.1 - 0.79 8.4 2.4 0.87 8.3 2.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LsmAD PF06741.13 KKA03110.1 - 4.2 8.0 8.0 2.5 8.7 4.8 2.1 1 1 1 2 2 2 0 LsmAD domain DUF3258 PF11646.8 KKA03111.1 - 0.028 14.5 0.9 0.028 14.5 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function DUF3258 Syntaxin-6_N PF09177.11 KKA03111.1 - 0.16 12.6 0.0 0.16 12.6 0.0 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DBINO PF13892.6 KKA03111.1 - 6.9 7.0 10.5 0.92 9.9 4.9 2.2 2 0 0 2 2 2 0 DNA-binding domain AhpC-TSA PF00578.21 KKA03112.1 - 1.7e-32 111.9 0.1 3.2e-32 111.1 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KKA03112.1 - 4.5e-16 58.9 0.1 7.2e-16 58.2 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 KKA03112.1 - 8.8e-08 31.9 0.1 1.7e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Metallophos PF00149.28 KKA03113.1 - 5.6e-05 23.7 0.8 0.0001 22.8 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Rota_NSP3 PF01665.16 KKA03113.1 - 0.038 13.1 0.8 0.092 11.9 0.8 1.6 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 CGI-121 PF08617.10 KKA03115.1 - 4.9e-06 26.8 4.0 7.1e-06 26.2 4.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MAT1 PF06391.13 KKA03116.1 - 1.3e-36 126.4 31.1 1.3e-36 126.4 31.1 1.4 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KKA03116.1 - 1.5e-26 92.1 9.0 2.7e-26 91.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKA03116.1 - 0.0017 18.2 4.7 0.0037 17.1 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKA03116.1 - 0.0022 18.3 7.1 0.0036 17.6 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKA03116.1 - 0.0042 16.9 5.1 0.012 15.5 5.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) L27 PF02828.16 KKA03116.1 - 0.11 12.3 3.5 6.2 6.7 0.7 2.7 3 0 0 3 3 3 0 L27 domain zf-RING_UBOX PF13445.6 KKA03116.1 - 0.13 12.3 7.5 0.25 11.4 7.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KKA03116.1 - 0.24 11.4 9.3 2.8 8.0 9.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 KKA03116.1 - 2.5 8.0 9.5 33 4.4 10.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain SLX9 PF15341.6 KKA03116.1 - 3 8.2 17.3 7.5 7.0 17.3 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF501 PF04417.12 KKA03116.1 - 5.1 6.9 8.8 0.71 9.7 3.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF501) Prok-RING_4 PF14447.6 KKA03116.1 - 5.3 7.0 8.7 77 3.3 0.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Exonuc_VII_L PF02601.15 KKA03116.1 - 8 5.9 13.1 12 5.4 13.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DHHC PF01529.20 KKA03117.1 - 5.1e-17 62.2 3.8 1.1e-16 61.2 3.8 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KKA03118.1 - 3.2e-27 94.9 0.9 5.9e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKA03118.1 - 5.6e-24 83.9 1.9 1.6e-08 34.7 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKA03118.1 - 1.4e-21 76.5 2.4 8.2e-07 29.5 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA03118.1 - 5.8e-18 63.1 0.5 0.0016 18.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KKA03118.1 - 6.4e-16 58.0 0.7 2.7e-06 27.6 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat DUF4422 PF14393.6 KKA03118.1 - 0.0023 17.8 0.1 0.0044 16.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4422) DUF3447 PF11929.8 KKA03118.1 - 0.013 15.5 1.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) zf-C3HC4_3 PF13920.6 KKA03119.1 - 4.4e-06 26.4 10.2 4.4e-06 26.4 10.2 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKA03119.1 - 0.0007 19.9 12.5 0.0007 19.9 12.5 3.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KKA03119.1 - 0.00075 19.3 14.4 0.00075 19.3 14.4 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ER PF01133.17 KKA03119.1 - 0.024 14.6 0.5 0.12 12.4 0.2 2.3 2 0 0 2 2 2 0 Enhancer of rudimentary zf-C3HC4_2 PF13923.6 KKA03119.1 - 0.053 13.4 18.7 0.035 13.9 13.3 3.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 KKA03119.1 - 0.088 13.7 18.2 7.9 7.6 0.2 6.4 5 0 0 5 5 5 0 C2H2-type zinc finger Phage_lambda_P PF06992.11 KKA03119.1 - 0.34 10.6 3.9 0.55 9.9 0.4 2.6 2 0 0 2 2 2 0 Replication protein P zf-RING_UBOX PF13445.6 KKA03119.1 - 4.9 7.3 17.8 0.3 11.2 11.7 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C2H2 PF00096.26 KKA03120.1 - 2.9e-10 40.0 10.8 2.6e-05 24.4 0.9 2.8 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA03120.1 - 1.5e-07 31.5 13.4 3.7e-05 24.0 0.4 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA03120.1 - 5.2e-07 30.0 8.4 0.0027 18.4 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKA03120.1 - 3.7e-06 26.8 6.5 0.00021 21.2 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KKA03120.1 - 0.00036 20.4 8.3 0.001 18.9 0.3 2.7 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 KKA03120.1 - 0.002 18.4 6.2 0.014 15.8 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KKA03120.1 - 0.0031 17.8 4.7 0.0079 16.5 4.7 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon C1_4 PF07975.12 KKA03120.1 - 0.0059 16.8 1.9 0.019 15.2 1.8 1.9 1 1 0 1 1 1 1 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 KKA03120.1 - 0.032 14.5 9.0 0.62 10.4 0.4 3.2 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKA03120.1 - 0.055 13.2 4.0 4.2 7.2 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KKA03120.1 - 0.99 10.1 9.1 0.74 10.5 0.4 3.3 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats FYDLN_acid PF09538.10 KKA03120.1 - 2.2 9.0 8.8 6.1 7.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FYVE PF01363.21 KKA03120.1 - 3.7 7.7 7.8 4.9 7.4 1.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HE PF16278.5 KKA03120.1 - 7 7.2 12.8 0.98 9.9 1.5 3.6 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Dfp1_Him1_M PF08630.10 KKA03121.1 - 2.8e-19 69.6 1.2 2.8e-19 69.6 1.2 3.4 3 1 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 KKA03121.1 - 8.2e-16 57.8 0.4 1.9e-15 56.7 0.4 1.7 1 0 0 1 1 1 1 DBF zinc finger IRF PF00605.17 KKA03121.1 - 0.16 12.3 5.8 0.18 12.1 0.8 3.5 3 0 0 3 3 3 0 Interferon regulatory factor transcription factor Sod_Fe_C PF02777.18 KKA03122.1 - 7.4e-12 45.3 0.8 3.4e-05 23.9 0.1 3.0 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain BTB_2 PF02214.22 KKA03122.1 - 0.035 14.5 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 BTB/POZ domain Sec23_trunk PF04811.15 KKA03123.1 - 2.9e-46 158.0 0.1 5.6e-46 157.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKA03123.1 - 5.9e-12 45.3 0.4 1.2e-10 41.1 0.2 2.6 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKA03123.1 - 1.5e-11 44.8 0.1 4.9e-11 43.2 0.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKA03123.1 - 5.7e-06 26.3 7.9 1.3e-05 25.1 7.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF1699 PF08004.11 KKA03123.1 - 0.029 14.1 0.7 0.1 12.3 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Asp PF00026.23 KKA03124.1 - 0.00012 21.6 10.1 0.00012 21.6 10.1 3.9 3 1 0 3 3 3 1 Eukaryotic aspartyl protease Rimk_N PF18030.1 KKA03124.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 RimK PreATP-grasp domain FAT PF02259.23 KKA03125.1 - 7.1e-58 196.5 6.7 7.1e-58 196.5 6.7 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KKA03125.1 - 4.4e-32 111.9 2.6 9.8e-32 110.7 2.6 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_2 PF07719.17 KKA03125.1 - 0.021 14.9 0.3 7.1 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKA03125.1 - 0.25 11.7 2.9 6.6 7.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HLH PF00010.26 KKA03126.1 - 5.3e-14 51.9 0.1 1.7e-13 50.3 0.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ATP-synt_E PF05680.12 KKA03128.1 - 2.2e-14 53.5 0.3 2.4e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.21 KKA03129.1 - 8.9e-05 22.6 0.1 0.00031 20.8 0.1 1.9 1 1 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KKA03129.1 - 0.023 14.4 1.2 0.092 12.5 1.2 2.1 1 0 0 1 1 1 0 Rabenosyn Rab binding domain GPHR_N PF12537.8 KKA03130.1 - 6e-07 29.5 0.6 1.4e-06 28.3 0.6 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF4501 PF14946.6 KKA03130.1 - 0.016 15.3 1.5 0.032 14.3 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) RseC_MucC PF04246.12 KKA03130.1 - 7.1 6.6 10.4 1.6 8.7 2.1 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ABA_GPCR PF12430.8 KKA03131.1 - 1.6e-07 31.3 6.8 2.5e-06 27.4 6.8 2.2 1 1 0 1 1 1 1 Abscisic acid G-protein coupled receptor Pkinase PF00069.25 KKA03132.1 - 2.3e-43 148.5 0.1 4.2e-31 108.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Ribonuc_2-5A PF06479.12 KKA03132.1 - 2.8e-36 124.5 2.5 2.9e-36 124.5 0.7 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KKA03132.1 - 1.5e-24 86.7 0.0 1.2e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KKA03132.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KKA03132.1 - 0.0069 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KKA03132.1 - 0.23 10.2 6.2 0.016 14.0 0.7 1.9 2 1 0 2 2 2 0 Fungal protein kinase ANAPC4_WD40 PF12894.7 KKA03133.1 - 0.00034 20.9 7.0 0.098 13.0 0.1 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CAMSAP_CKK PF08683.11 KKA03133.1 - 0.032 14.4 0.5 2.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated WD40 PF00400.32 KKA03133.1 - 0.77 10.7 4.5 1.8 9.6 0.1 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Plus-3 PF03126.18 KKA03134.1 - 2.4e-21 76.3 0.2 1e-20 74.2 0.2 2.1 1 0 0 1 1 1 1 Plus-3 domain Mannosyl_trans3 PF11051.8 KKA03135.1 - 3.3e-76 256.3 0.4 3.3e-76 256.3 0.4 1.4 2 0 0 2 2 2 1 Mannosyltransferase putative Cnl2_NKP2 PF09447.10 KKA03136.1 - 0.059 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Thyroglobulin_1 PF00086.18 KKA03138.1 - 0.44 10.3 1.7 8.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat CTP_transf_1 PF01148.20 KKA03140.1 - 8.8e-77 258.4 19.6 1.2e-76 258.0 19.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family ATP-synt_DE_N PF02823.16 KKA03141.1 - 2.3e-13 49.9 0.0 3.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Med2 PF11214.8 KKA03142.1 - 0.00078 19.6 2.9 0.0024 18.0 2.9 1.9 1 0 0 1 1 1 1 Mediator complex subunit 2 Med29 PF11568.8 KKA03142.1 - 0.01 16.1 0.5 0.01 16.1 0.5 2.9 3 1 0 3 3 3 0 Mediator complex subunit 29 DUF21 PF01595.20 KKA03143.1 - 3.8e-30 104.9 0.2 5.7e-30 104.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KKA03143.1 - 0.00041 20.7 0.3 1.5 9.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain Steroid_dh PF02544.16 KKA03144.1 - 1.3e-26 93.4 6.5 2.2e-26 92.7 6.5 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KKA03144.1 - 0.0014 19.0 0.4 0.0028 18.0 0.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KKA03144.1 - 0.013 15.9 0.2 0.032 14.6 0.2 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Acp26Ab PF05777.12 KKA03144.1 - 0.068 13.8 0.4 0.24 12.0 0.1 2.0 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Pkinase PF00069.25 KKA03145.1 - 8e-48 163.1 2.2 2.9e-32 112.1 0.2 3.5 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03145.1 - 1.4e-22 80.2 0.5 2.1e-18 66.6 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KKA03145.1 - 3.6e-05 23.8 0.0 0.00014 21.9 0.0 1.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKA03145.1 - 7.7e-05 21.6 0.2 0.00016 20.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKA03145.1 - 7.8e-05 22.1 0.0 0.0059 16.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KKA03145.1 - 0.0042 16.7 0.1 0.027 14.1 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KKA03145.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MetW PF07021.12 KKA03145.1 - 0.088 12.4 0.1 4.1 7.0 0.0 2.9 2 1 1 3 3 3 0 Methionine biosynthesis protein MetW EMP24_GP25L PF01105.24 KKA03146.1 - 8.6e-27 94.2 0.7 1.2e-26 93.8 0.7 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ATP-synt_8 PF00895.20 KKA03146.1 - 0.0017 18.8 0.5 0.004 17.6 0.5 1.6 1 0 0 1 1 1 1 ATP synthase protein 8 SdrD_B PF17210.3 KKA03146.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 SdrD B-like domain Fungal_trans PF04082.18 KKA03147.1 - 6.9e-12 45.0 5.2 1.5e-11 43.8 4.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA03147.1 - 0.00053 20.1 4.1 0.00098 19.2 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArsR PF09824.9 KKA03147.1 - 0.064 12.9 3.0 0.06 13.0 0.6 2.2 2 0 0 2 2 2 0 ArsR transcriptional regulator Mannosyl_trans3 PF11051.8 KKA03148.1 - 1.4e-33 116.5 0.5 2.8e-33 115.5 0.5 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Hom_end_hint PF05203.16 KKA03148.1 - 0.029 14.3 0.6 0.066 13.1 0.2 1.8 2 0 0 2 2 2 0 Hom_end-associated Hint DUF2540 PF10802.8 KKA03148.1 - 0.13 12.3 2.1 0.25 11.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) AAA PF00004.29 KKA03149.1 - 4.9e-42 143.5 0.1 7.6e-41 139.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA03149.1 - 9.5e-12 44.5 0.3 2.6e-11 43.1 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KKA03149.1 - 1.4e-09 37.7 0.1 2.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KKA03149.1 - 3.6e-07 30.4 0.4 7.1e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKA03149.1 - 7.9e-06 25.2 0.0 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KKA03149.1 - 8.5e-06 25.8 0.0 3.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKA03149.1 - 1.5e-05 25.3 1.7 0.018 15.3 0.1 2.8 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 KKA03149.1 - 0.00015 22.2 0.1 0.0014 19.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KKA03149.1 - 0.00037 20.3 0.1 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKA03149.1 - 0.0032 17.7 0.0 0.0073 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KKA03149.1 - 0.0047 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKA03149.1 - 0.0095 16.1 0.1 0.031 14.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KKA03149.1 - 0.012 16.2 0.1 0.036 14.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KKA03149.1 - 0.014 15.0 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_3 PF07726.11 KKA03149.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKA03149.1 - 0.016 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KKA03149.1 - 0.018 14.2 0.1 0.044 13.0 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KKA03149.1 - 0.023 14.1 0.2 0.5 9.7 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 KKA03149.1 - 0.035 13.7 1.5 0.53 9.8 0.4 2.5 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKA03149.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKA03149.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KKA03149.1 - 0.086 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KKA03149.1 - 0.092 12.7 0.1 0.64 9.9 0.1 2.2 1 1 1 2 2 2 0 NACHT domain DUF2075 PF09848.9 KKA03149.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KKA03149.1 - 0.2 11.3 2.1 0.29 10.8 0.3 2.3 2 1 0 2 2 2 0 AAA domain Rad21_Rec8_N PF04825.13 KKA03150.1 - 4.9e-07 29.9 0.8 4.9e-07 29.9 0.8 1.9 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KKA03150.1 - 0.00035 19.8 0.0 0.00075 18.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein RGS PF00615.19 KKA03151.1 - 0.42 10.9 2.9 4.2 7.7 1.0 2.7 2 1 0 2 2 2 0 Regulator of G protein signaling domain GATase PF00117.28 KKA03152.1 - 2.3e-45 154.7 0.1 3.6e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KKA03152.1 - 1.8e-44 150.6 0.0 3.7e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KKA03152.1 - 0.00018 21.3 0.8 0.005 16.6 0.8 2.6 1 1 0 1 1 1 1 Peptidase C26 RCC1_2 PF13540.6 KKA03153.1 - 4.3e-07 29.6 0.6 0.021 14.6 0.0 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KKA03153.1 - 0.036 14.3 9.9 0.028 14.6 1.6 3.7 1 1 2 3 3 3 0 BTB/POZ domain DUF3666 PF12408.8 KKA03153.1 - 0.058 12.6 0.3 0.18 11.0 0.3 1.8 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase ATP-synt_ab PF00006.25 KKA03154.1 - 7.3e-116 385.3 0.0 1.2e-115 384.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KKA03154.1 - 3.1e-46 156.2 0.0 6.8e-46 155.1 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KKA03154.1 - 4.7e-16 59.1 1.5 1e-15 58.0 1.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.6 KKA03154.1 - 0.044 13.8 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNase_3_N PF18497.1 KKA03155.1 - 3.2e-20 72.3 0.3 3.2e-20 72.3 0.3 2.5 2 0 0 2 2 2 1 Ribonuclease III N-terminal domain Ribonuclease_3 PF00636.26 KKA03155.1 - 7.8e-17 61.8 0.0 4e-16 59.5 0.0 2.3 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKA03155.1 - 4.9e-14 52.6 0.1 9.9e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KKA03155.1 - 0.0024 18.6 0.0 0.0079 16.9 0.0 2.0 1 1 0 1 1 1 1 Double-stranded RNA binding motif SNF2_N PF00176.23 KKA03156.1 - 1.6e-70 237.6 3.4 6.5e-70 235.6 3.4 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA03156.1 - 3.9e-20 72.3 0.3 1.5e-19 70.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SLIDE PF09111.10 KKA03156.1 - 1.7e-19 69.9 3.2 1.7e-19 69.9 3.2 3.6 5 0 0 5 5 5 1 SLIDE HAND PF09110.11 KKA03156.1 - 9.2e-13 48.9 8.2 9.2e-13 48.9 8.2 5.5 4 1 1 6 6 6 2 HAND ResIII PF04851.15 KKA03156.1 - 1e-09 38.6 0.0 1e-09 38.6 0.0 3.9 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKA03156.1 - 4.3e-05 23.4 0.0 0.00027 20.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DIL PF01843.19 KKA03157.1 - 3e-07 30.7 6.1 5.6e-06 26.6 3.1 3.0 2 1 0 2 2 2 1 DIL domain CKS PF01111.19 KKA03158.1 - 1.1e-33 115.3 0.6 2.1e-33 114.4 0.6 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PI3_PI4_kinase PF00454.27 KKA03159.1 - 3.9e-51 174.3 2.8 2.7e-50 171.5 2.8 2.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 KKA03159.1 - 2.4e-11 43.5 1.9 7.2e-11 41.9 0.2 2.9 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 KKA03159.1 - 4.8e-07 29.5 0.2 1.3e-06 28.1 0.2 1.9 1 0 0 1 1 1 1 FATC domain FimH_man-bind PF09160.10 KKA03159.1 - 0.19 11.4 2.8 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 FimH, mannose binding PRK PF00485.18 KKA03161.1 - 2.5e-56 190.6 0.0 3.9e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KKA03161.1 - 2.5e-08 33.5 0.0 4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KKA03161.1 - 4.7e-07 30.4 0.4 2.7e-06 28.0 0.0 2.1 1 1 2 3 3 3 1 AAA domain KAP_NTPase PF07693.14 KKA03161.1 - 0.00026 20.4 0.0 0.00065 19.0 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 KKA03161.1 - 0.0011 19.2 0.0 0.01 16.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKA03161.1 - 0.003 18.0 0.0 0.0061 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 KKA03161.1 - 0.0038 17.1 0.0 0.0089 15.9 0.0 1.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 KKA03161.1 - 0.004 17.0 0.3 0.028 14.3 0.3 2.2 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_23 PF13476.6 KKA03161.1 - 0.0098 16.4 1.6 4.2 7.8 0.8 2.2 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KKA03161.1 - 0.022 15.3 0.0 0.062 13.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin PF02224.18 KKA03161.1 - 0.024 14.4 0.1 2 8.1 0.0 2.6 3 0 0 3 3 3 0 Cytidylate kinase NACHT PF05729.12 KKA03161.1 - 0.033 14.1 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 KKA03161.1 - 0.036 14.0 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_5 PF07728.14 KKA03161.1 - 0.051 13.6 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KKA03161.1 - 0.06 13.8 1.8 1.3 9.5 0.3 2.9 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KKA03161.1 - 0.089 13.0 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Transposase_22 PF02994.14 KKA03161.1 - 0.1 12.8 0.9 0.25 11.5 0.4 1.9 2 0 0 2 2 2 0 L1 transposable element RBD-like domain CbiA PF01656.23 KKA03161.1 - 0.12 12.5 1.8 1.1 9.3 1.8 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 KKA03161.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF87 PF01935.17 KKA03161.1 - 2.7 8.0 7.4 1.9 8.5 0.3 2.8 2 1 0 3 3 3 0 Helicase HerA, central domain CitMHS PF03600.16 KKA03162.1 - 4.1e-26 91.9 38.0 9.7e-18 64.4 15.2 2.1 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 KKA03162.1 - 3.5e-25 89.7 17.1 6.4e-14 52.7 0.4 3.6 2 1 2 4 4 4 3 SPX domain Na_sulph_symp PF00939.19 KKA03162.1 - 8.9e-24 84.3 36.7 1.4e-23 83.7 36.7 1.3 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Dus PF01207.17 KKA03163.1 - 5.8e-43 147.1 0.2 1.8e-42 145.5 0.2 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PFK PF00365.20 KKA03163.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase TMP-TENI PF02581.17 KKA03163.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Rrn6 PF10214.9 KKA03163.1 - 0.67 8.4 6.4 0.87 8.0 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tim17 PF02466.19 KKA03164.1 - 4.2e-24 85.1 1.9 5.5e-24 84.7 1.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HIG_1_N PF04588.13 KKA03165.1 - 4.2e-07 30.1 0.2 7.6e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3169 PF11368.8 KKA03165.1 - 0.00078 19.0 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Ribosomal_L19 PF01245.20 KKA03166.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 AAA_23 PF13476.6 KKA03166.1 - 2.3 8.7 8.8 3.2 8.2 8.7 1.7 1 1 0 1 1 1 0 AAA domain WBS_methylT PF12589.8 KKA03167.1 - 2.6e-13 50.5 2.7 2.6e-13 50.5 2.7 2.0 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_12 PF08242.12 KKA03167.1 - 9e-09 36.0 0.0 2.7e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA03167.1 - 2.1e-08 34.7 0.0 6.3e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA03167.1 - 2.1e-08 34.7 0.0 3.3e-07 30.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKA03167.1 - 3.6e-08 33.4 0.1 6.9e-05 22.7 0.0 2.9 2 1 0 3 3 3 2 Methyltransferase domain CMAS PF02353.20 KKA03167.1 - 0.0026 17.1 0.0 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KKA03167.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KKA03167.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BNR_assoc_N PF14873.6 KKA03167.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase MBOAT PF03062.19 KKA03169.1 - 1.1e-43 149.9 34.5 1.1e-43 149.9 34.5 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KKA03169.1 - 1.2e-05 25.5 4.6 3.8e-05 23.9 4.6 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Com_YlbF PF06133.11 KKA03169.1 - 0.13 12.9 1.4 0.27 11.8 1.4 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Ank_5 PF13857.6 KKA03170.1 - 6.3e-13 48.7 0.5 1.1e-09 38.3 0.1 3.5 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKA03170.1 - 3.5e-10 40.3 0.1 7.5e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKA03170.1 - 6.1e-09 36.3 0.9 0.0044 17.6 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKA03170.1 - 1.2e-07 31.5 1.4 0.001 19.4 0.1 4.5 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.30 KKA03170.1 - 2.2e-05 24.7 0.1 0.04 14.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat MPP6 PF10175.9 KKA03171.1 - 5e-10 40.0 26.5 8.6e-10 39.2 26.5 1.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Ytp1 PF10355.9 KKA03172.1 - 1.6e-92 309.7 7.7 2.5e-92 309.0 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KKA03172.1 - 1.7e-18 66.3 7.3 1.7e-18 66.3 7.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF373 PF04123.13 KKA03172.1 - 5 6.5 13.3 0.18 11.2 4.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF373) G10 PF01125.17 KKA03173.1 - 2.2e-37 128.0 7.9 3.2e-37 127.5 7.9 1.2 1 0 0 1 1 1 1 G10 protein zf-C3HC4 PF00097.25 KKA03174.1 - 5.9e-09 35.7 14.6 5.9e-09 35.7 14.6 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKA03174.1 - 9.9e-09 34.9 18.4 1.7e-08 34.2 13.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKA03174.1 - 2.9e-07 30.4 5.9 2.9e-07 30.4 5.9 3.4 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKA03174.1 - 2.7e-06 27.1 20.4 3.1e-06 26.9 11.0 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KKA03174.1 - 7.4e-06 25.7 7.6 8.1e-06 25.6 5.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KKA03174.1 - 1.1e-05 25.2 16.8 0.00051 19.8 10.6 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKA03174.1 - 1.3e-05 25.1 19.0 2.9e-05 23.9 13.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKA03174.1 - 3.2e-05 24.2 18.9 7e-05 23.1 13.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KKA03174.1 - 0.00012 22.2 13.1 0.00012 22.2 13.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KKA03174.1 - 0.0037 17.5 13.9 0.0097 16.2 9.0 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KKA03174.1 - 0.0046 16.8 11.8 0.016 15.0 7.5 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KKA03174.1 - 0.01 15.7 7.5 0.76 9.7 2.2 3.2 2 0 0 2 2 2 2 Rad50 zinc hook motif U-box PF04564.15 KKA03174.1 - 0.01 16.0 0.2 0.045 13.9 0.0 2.2 2 0 0 2 2 2 0 U-box domain UBZ_FAAP20 PF15750.5 KKA03174.1 - 0.026 14.4 1.4 0.4 10.7 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-ANAPC11 PF12861.7 KKA03174.1 - 0.17 12.0 5.3 1.1 9.4 2.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-C2H2_12 PF18112.1 KKA03174.1 - 0.8 10.2 7.6 0.69 10.4 0.4 3.0 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain Phos_pyr_kin PF08543.12 KKA03175.1 - 0.00053 19.4 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Lipase_3 PF01764.25 KKA03176.1 - 2.5e-08 33.9 0.0 6e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 KKA03176.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKA03176.1 - 0.095 13.3 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KKA03176.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RING_2 PF13639.6 KKA03178.1 - 1.2e-06 28.8 16.8 1.2e-06 28.8 16.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KKA03178.1 - 1.2e-05 25.1 19.1 1.2e-05 25.1 19.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKA03178.1 - 0.00015 21.7 14.0 0.00015 21.7 14.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKA03178.1 - 0.00042 20.1 17.5 0.00042 20.1 17.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKA03178.1 - 0.0019 18.0 3.3 0.0019 18.0 3.3 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 DUF1610 PF07754.11 KKA03178.1 - 0.013 15.4 4.5 1.5 8.8 2.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) zinc_ribbon_4 PF13717.6 KKA03178.1 - 0.016 15.2 13.5 1.4 8.9 0.2 4.8 5 0 0 5 5 5 0 zinc-ribbon domain zf-RING_5 PF14634.6 KKA03178.1 - 0.027 14.5 22.2 0.21 11.6 14.1 3.4 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKA03178.1 - 0.037 14.2 17.4 0.037 14.2 17.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KKA03178.1 - 1.2 9.0 14.4 0.87 9.4 11.3 2.2 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_4 PF13894.6 KKA03178.1 - 2.2 9.3 0.1 2.2 9.3 0.1 4.4 4 1 1 5 5 5 0 C2H2-type zinc finger zf-rbx1 PF12678.7 KKA03178.1 - 2.7 8.4 22.8 0.17 12.2 14.4 2.7 2 1 1 3 3 3 0 RING-H2 zinc finger domain HAD_SAK_1 PF10307.9 KKA03179.1 - 7.4e-35 120.6 5.6 7.4e-35 120.6 5.6 2.2 2 0 0 2 2 2 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Bact_lectin PF18483.1 KKA03179.1 - 0.88 9.6 7.8 0.35 10.9 1.0 2.4 2 1 0 2 2 2 0 Bacterial lectin SQS_PSY PF00494.19 KKA03180.1 - 2.7e-33 115.6 0.0 3.4e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Gtr1_RagA PF04670.12 KKA03181.1 - 1.5e-83 279.7 5.1 2.6e-83 278.9 5.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA03181.1 - 1.5e-08 34.7 0.1 1.2e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KKA03181.1 - 9.7e-07 29.0 0.3 3.6e-05 23.9 0.1 2.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKA03181.1 - 2.9e-06 27.0 0.3 4.4e-05 23.1 0.3 2.3 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KKA03181.1 - 2.4e-05 23.9 3.2 0.00029 20.4 1.1 2.8 2 2 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 KKA03181.1 - 0.005 17.4 0.6 0.026 15.1 0.1 2.1 2 1 0 2 2 2 1 ABC transporter CRISPR_Cas9_WED PF18061.1 KKA03181.1 - 0.02 15.0 3.7 0.021 14.9 1.4 2.1 2 0 0 2 2 2 0 CRISPR-Cas9 WED domain DUF815 PF05673.13 KKA03181.1 - 0.021 14.0 0.0 0.053 12.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Acetyltransf_19 PF18015.1 KKA03181.1 - 0.034 14.4 0.8 0.034 14.4 0.8 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_29 PF13555.6 KKA03181.1 - 0.065 13.0 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKA03181.1 - 0.23 11.3 1.8 2 8.3 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase Glyco_hydro_49 PF03718.13 KKA03181.1 - 0.46 10.5 4.7 0.31 11.0 1.6 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 NLPC_P60 PF00877.19 KKA03182.1 - 0.11 12.6 0.8 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 NlpC/P60 family Cue1_U7BR PF18499.1 KKA03183.1 - 0.00013 22.0 3.2 0.00026 21.0 3.2 1.6 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 Rit1_C PF17184.4 KKA03184.1 - 2.7e-54 184.4 0.2 4.9e-54 183.6 0.2 1.3 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KKA03184.1 - 1.6e-07 31.6 0.3 4.2e-07 30.3 0.3 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF5439 PF17507.2 KKA03184.1 - 0.029 14.6 0.2 0.09 13.0 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5439) SAP30_Sin3_bdg PF13867.6 KKA03186.1 - 1.5e-08 34.9 11.1 4.4e-08 33.3 0.5 3.1 3 0 0 3 3 3 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF413 PF04219.12 KKA03186.1 - 0.045 13.8 0.5 0.045 13.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF CRCB PF02537.15 KKA03187.1 - 3e-23 82.0 16.9 4.7e-14 52.5 4.3 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) EamA PF00892.20 KKA03187.1 - 0.72 10.0 18.5 2.2 8.5 6.2 3.1 3 0 0 3 3 3 0 EamA-like transporter family Glyco_transf_20 PF00982.21 KKA03188.1 - 1.2e-142 476.0 0.4 1.8e-142 475.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKA03188.1 - 4.6e-27 94.7 0.0 9.7e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase RRM PF10378.9 KKA03188.1 - 0.14 11.9 2.6 0.32 10.7 0.1 2.8 2 0 0 2 2 2 0 Putative RRM domain Ribosomal_L30 PF00327.20 KKA03189.1 - 0.19 11.6 4.1 5.9 6.9 4.1 2.4 1 1 0 1 1 1 0 Ribosomal protein L30p/L7e Ribosomal_L10 PF00466.20 KKA03191.1 - 7.2e-26 90.3 1.0 7.2e-26 90.3 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KKA03191.1 - 1.5e-21 76.1 0.1 2.7e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KKA03191.1 - 2.3e-17 63.4 6.1 2.3e-17 63.4 6.1 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein DXP_reductoisom PF02670.16 KKA03191.1 - 0.054 14.2 1.0 0.18 12.5 0.0 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF5497 PF17601.2 KKA03192.1 - 0.0019 18.5 0.7 0.0019 18.5 0.7 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5497) Abhydrolase_1 PF00561.20 KKA03193.1 - 1.7e-17 63.9 0.0 2e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKA03193.1 - 5.2e-12 46.8 0.0 1.2e-11 45.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKA03193.1 - 1.8e-06 27.4 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKA03193.1 - 0.0038 17.0 0.1 0.043 13.5 0.1 2.4 2 1 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 KKA03193.1 - 0.0095 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Lipase_2 PF01674.18 KKA03193.1 - 0.036 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) DUF676 PF05057.14 KKA03193.1 - 0.037 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 KKA03193.1 - 0.053 13.0 0.0 7.7 5.9 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KKA03193.1 - 0.067 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 KKA03193.1 - 0.085 12.2 0.0 5.2 6.3 0.0 2.8 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) YL1_C PF08265.11 KKA03193.1 - 0.18 11.6 0.5 0.4 10.5 0.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Glyco_hydro_47 PF01532.20 KKA03194.1 - 4.6e-68 230.2 4.5 6.7e-68 229.7 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DAGK_cat PF00781.24 KKA03195.1 - 1.3e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GatB_Yqey PF02637.18 KKA03195.1 - 0.093 12.6 0.6 0.79 9.6 0.4 2.3 2 0 0 2 2 2 0 GatB domain UQ_con PF00179.26 KKA03196.1 - 1e-50 171.1 0.0 1.1e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKA03196.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.6 KKA03196.1 - 0.0029 17.3 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Bromodomain PF00439.25 KKA03197.1 - 1.2e-16 60.6 2.1 2.3e-16 59.6 0.6 2.4 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KKA03197.1 - 0.028 14.4 0.0 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Bromodomain associated CLASP_N PF12348.8 KKA03198.1 - 3e-08 33.5 17.5 7.8e-07 28.9 9.1 2.9 4 0 0 4 4 4 2 CLASP N terminal Glutaredoxin2_C PF04399.13 KKA03198.1 - 0.1 12.4 2.8 2.6 7.9 0.2 3.2 3 1 0 3 3 3 0 Glutaredoxin 2, C terminal domain DNA_pol_E_B PF04042.16 KKA03199.1 - 1e-19 70.7 1.2 1.9e-19 69.9 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TMP-TENI PF02581.17 KKA03199.1 - 0.0017 17.7 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase Ala_racemase_N PF01168.20 KKA03200.1 - 2.4e-20 73.1 0.0 3e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3067 PF11267.8 KKA03200.1 - 0.018 15.6 0.1 0.037 14.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) NodS PF05401.11 KKA03201.1 - 0.0083 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) rve_2 PF13333.6 KKA03201.1 - 0.15 12.3 2.0 0.94 9.7 2.0 2.5 1 0 0 1 1 1 0 Integrase core domain DNA_pol3_delta2 PF13177.6 KKA03202.1 - 5.2e-11 42.6 3.0 5.2e-11 42.6 3.0 2.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.6 KKA03202.1 - 0.001 19.2 0.0 0.062 13.4 0.1 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 KKA03202.1 - 0.0013 18.7 0.4 0.0083 16.1 0.2 2.3 2 1 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 KKA03202.1 - 0.0035 17.8 0.5 0.013 16.0 0.5 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KKA03202.1 - 0.014 15.8 0.2 0.052 14.0 0.1 2.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain AAA_24 PF13479.6 KKA03202.1 - 0.035 13.8 1.4 0.097 12.4 0.4 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKA03202.1 - 0.073 13.6 0.5 0.15 12.6 0.4 1.6 1 1 0 1 1 1 0 ABC transporter Spuma_A9PTase PF03539.14 KKA03202.1 - 0.075 13.2 0.3 0.43 10.7 0.3 2.1 1 1 0 1 1 1 0 Spumavirus aspartic protease (A9) IstB_IS21 PF01695.17 KKA03202.1 - 0.09 12.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein tRNA-synt_2d PF01409.20 KKA03203.1 - 3.2e-43 148.0 0.3 2.2e-26 92.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KKA03203.1 - 1.4e-17 63.9 0.3 3.9e-17 62.5 0.1 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Phage_connector PF05352.12 KKA03203.1 - 0.002 17.6 0.1 0.0042 16.6 0.1 1.5 1 0 0 1 1 1 1 Phage Connector (GP10) tRNA-synt_2 PF00152.20 KKA03203.1 - 0.017 14.2 0.2 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) FAD_binding_1 PF00667.20 KKA03204.1 - 1.1e-21 77.5 0.4 1.6e-13 50.8 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Flavodoxin_1 PF00258.25 KKA03204.1 - 2.3e-13 50.6 0.0 4.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KKA03204.1 - 1.9e-07 31.7 0.0 4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain UvsY PF11056.8 KKA03204.1 - 0.01 16.2 0.2 0.026 14.8 0.2 1.7 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY Acetyltransf_1 PF00583.25 KKA03205.1 - 6.2e-15 55.5 0.0 8.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKA03205.1 - 3.8e-09 36.8 0.2 6.6e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKA03205.1 - 7.7e-06 25.9 0.1 1.3e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKA03205.1 - 0.0002 21.3 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein RTP1_C1 PF10363.9 KKA03205.1 - 0.077 13.2 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Acetyltransf_8 PF13523.6 KKA03205.1 - 0.094 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Tim10_DDP PF02953.15 KKA03206.1 - 4.9e-15 54.9 1.2 4.9e-15 54.9 1.2 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger TTL PF03133.15 KKA03207.1 - 3.1e-67 226.8 2.8 4.4e-67 226.3 1.4 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KKA03207.1 - 4e-27 95.3 0.2 1.4e-26 93.5 0.1 2.0 2 1 0 2 2 2 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KKA03207.1 - 4.2e-05 22.9 0.0 0.00032 20.0 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp Pkinase PF00069.25 KKA03208.1 - 3.4e-66 223.3 0.2 4e-66 223.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03208.1 - 1e-29 103.6 0.2 1.9e-29 102.8 0.2 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA03208.1 - 2.9e-05 23.2 0.2 5.1e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKA03208.1 - 0.14 11.5 0.3 0.63 9.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKA03209.1 - 3.8e-12 46.1 8.0 3.8e-12 46.1 8.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03209.1 - 5.4e-05 22.6 0.8 0.22 10.7 0.2 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KKA03212.1 - 3.7e-05 23.9 0.2 0.0096 16.2 0.0 3.6 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKA03212.1 - 0.0017 19.1 0.0 6.6 7.8 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat LisH_TPL PF17814.1 KKA03212.1 - 0.026 14.2 0.2 0.096 12.4 0.2 2.0 1 0 0 1 1 1 0 LisH-like dimerisation domain WD40_3 PF15911.5 KKA03212.1 - 0.036 14.1 0.2 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF4988 PF16378.5 KKA03212.1 - 6.1 6.5 16.1 0.72 9.5 0.3 4.6 3 1 1 4 4 4 0 Domain of unknown function Tfb4 PF03850.14 KKA03213.1 - 9.1e-65 218.9 19.6 2.3e-50 171.6 7.5 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 Arc_PepC PF06819.11 KKA03213.1 - 0.025 14.7 2.2 0.027 14.6 0.3 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Mito_carr PF00153.27 KKA03214.1 - 7.2e-49 163.7 0.8 6e-18 64.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1129 PF06570.11 KKA03214.1 - 0.018 14.5 0.2 0.5 9.8 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) CM_2 PF01817.21 KKA03215.1 - 0.0021 18.3 0.4 0.051 13.9 0.1 2.5 2 0 0 2 2 2 1 Chorismate mutase type II HMG_box PF00505.19 KKA03216.1 - 6.4e-18 64.9 0.5 6.4e-18 64.9 0.5 3.0 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKA03216.1 - 1.7e-05 25.3 0.1 1.7e-05 25.3 0.1 3.4 3 0 0 3 3 3 1 HMG-box domain Pho88 PF10032.9 KKA03217.1 - 5.2e-45 152.9 2.1 5.8e-45 152.8 2.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TMEM240 PF15207.6 KKA03217.1 - 0.045 13.4 0.1 0.065 12.9 0.1 1.1 1 0 0 1 1 1 0 TMEM240 family Fe-S_biosyn PF01521.20 KKA03218.1 - 7e-11 42.3 0.1 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Glycos_transf_1 PF00534.20 KKA03219.1 - 1.1e-08 34.9 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKA03219.1 - 6.4e-08 33.1 0.0 2e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKA03219.1 - 8.7e-06 26.0 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKA03219.1 - 0.0043 17.1 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 YpmT PF17431.2 KKA03219.1 - 0.017 15.1 1.6 0.047 13.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like DUF1151 PF06625.11 KKA03219.1 - 0.019 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Lge1 PF11488.8 KKA03219.1 - 0.51 10.6 4.0 0.45 10.7 1.8 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Med1 PF10744.9 KKA03220.1 - 1.8e-16 60.2 2.3 2.5e-16 59.8 2.3 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 KKA03221.1 - 1.1e-21 77.4 0.4 7.2e-12 45.2 0.3 3.4 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03221.1 - 7e-12 45.2 0.0 4.1e-10 39.4 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKA03221.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKA03221.1 - 0.00046 19.6 0.1 0.00079 18.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKA03221.1 - 0.0094 14.8 0.2 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase CagZ PF09053.10 KKA03221.1 - 0.038 13.6 0.3 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 CagZ Choline_kinase PF01633.20 KKA03221.1 - 0.045 13.3 2.8 0.2 11.2 0.2 2.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase WD40 PF00400.32 KKA03222.1 - 0.0018 19.1 0.1 10 7.1 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2140 PF09911.9 KKA03222.1 - 0.11 12.1 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) STE2 PF02116.15 KKA03223.1 - 3.9e-86 288.8 18.4 4.7e-86 288.6 18.4 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PalH PF08733.10 KKA03223.1 - 0.034 13.1 20.3 0.76 8.7 0.5 2.2 1 1 1 2 2 2 0 PalH/RIM21 YiaAB PF05360.14 KKA03223.1 - 0.065 13.5 0.6 0.21 11.8 0.6 1.9 1 0 0 1 1 1 0 yiaA/B two helix domain DUF3835 PF12927.7 KKA03225.1 - 3.7e-08 34.1 9.5 3.7e-08 34.1 9.5 8.1 6 4 1 8 8 8 2 Domain of unknown function (DUF3835) DUF1451 PF07295.11 KKA03227.1 - 1.4 8.9 8.4 2.5 8.1 6.3 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain Fcf2 PF08698.11 KKA03228.1 - 1.9e-12 47.4 1.6 1.9e-12 47.4 1.6 2.3 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Zwint PF15556.6 KKA03228.1 - 0.1 12.1 1.4 0.15 11.6 1.4 1.2 1 0 0 1 1 1 0 ZW10 interactor bZIP_1 PF00170.21 KKA03228.1 - 4.2 7.6 10.1 15 5.8 0.3 3.4 3 0 0 3 3 3 0 bZIP transcription factor GATA PF00320.27 KKA03229.1 - 5.7e-16 57.8 2.4 1e-15 57.0 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Ntox14 PF15522.6 KKA03229.1 - 0.095 12.1 0.0 0.6 9.5 0.0 2.2 3 0 0 3 3 3 0 Novel toxin 14 PPR_2 PF13041.6 KKA03230.1 - 0.00019 21.5 0.2 0.0017 18.5 0.1 2.6 2 0 0 2 2 2 1 PPR repeat family Thymidylate_kin PF02223.17 KKA03231.1 - 2.7e-37 128.3 0.0 3.1e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KKA03231.1 - 0.00061 20.3 1.0 0.0013 19.2 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KKA03231.1 - 0.69 10.0 3.4 0.68 10.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 KKA03232.1 - 8.1e-12 45.3 10.5 9.5e-12 45.1 10.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.29 KKA03233.1 - 5.5e-29 101.3 0.0 1.8e-28 99.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKA03233.1 - 0.0066 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKA03233.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KKA03234.1 - 1.7e-39 135.8 1.4 6.1e-39 134.0 0.2 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03234.1 - 9e-20 71.0 0.4 8.2e-18 64.6 0.2 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KKA03234.1 - 1e-05 25.0 2.1 1.1e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKA03234.1 - 0.0017 18.3 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKA03234.1 - 0.003 16.9 0.1 1.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KKA03234.1 - 0.017 14.7 0.3 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KKA03234.1 - 0.036 12.8 0.3 0.083 11.7 0.3 1.7 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KKA03234.1 - 0.054 13.1 0.2 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GHL10 PF02638.15 KKA03234.1 - 0.25 10.4 3.6 2.2 7.3 0.6 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase-like 10 TAL_FSA PF00923.19 KKA03235.1 - 4e-91 305.3 4.1 4.6e-91 305.1 4.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase HydF_dimer PF18128.1 KKA03235.1 - 0.11 12.5 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain Antimicrobial_7 PF08102.11 KKA03235.1 - 0.22 11.7 2.2 4.3 7.6 0.4 2.8 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Zn_clus PF00172.18 KKA03236.1 - 0.00028 20.9 8.6 0.00028 20.9 8.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0506 PF11703.8 KKA03236.1 - 0.25 11.8 6.5 0.8 10.1 6.5 1.8 1 1 0 1 1 1 0 UPF0506 Pkinase PF00069.25 KKA03238.1 - 7.3e-55 186.2 0.2 1.5e-54 185.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03238.1 - 6.9e-27 94.3 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA03238.1 - 0.00011 21.3 0.9 0.00031 19.8 0.9 1.8 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKA03238.1 - 0.022 14.1 0.1 0.041 13.2 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_sheath_1C PF17482.2 KKA03238.1 - 0.099 12.6 0.2 0.21 11.5 0.2 1.7 1 1 0 1 1 1 0 Phage tail sheath C-terminal domain FTA2 PF13095.6 KKA03238.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CN_hydrolase PF00795.22 KKA03239.1 - 1.5e-51 175.3 0.0 1.7e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase bZIP_1 PF00170.21 KKA03240.1 - 0.0011 19.0 9.9 0.0011 19.0 9.9 2.7 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KKA03240.1 - 0.028 14.5 10.8 0.028 14.5 10.8 2.6 2 1 1 3 3 3 0 Basic region leucine zipper Renin_r PF07850.14 KKA03240.1 - 0.15 12.6 0.6 1.5 9.5 0.2 2.1 2 0 0 2 2 2 0 Renin receptor-like protein Aminotran_5 PF00266.19 KKA03241.1 - 3.6e-08 32.8 0.0 1.4e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DUF3922 PF13059.6 KKA03241.1 - 0.35 11.4 5.9 4.4 7.8 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3992) IMUP PF15761.5 KKA03242.1 - 0.031 14.9 4.9 0.031 14.9 4.9 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein MA3 PF02847.17 KKA03243.1 - 4.4e-08 33.1 2.2 5.1e-07 29.7 0.1 3.4 3 0 0 3 3 3 1 MA3 domain NLE PF08154.12 KKA03243.1 - 1.4 9.5 4.7 0.59 10.7 1.0 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain Ribosomal_S25 PF03297.15 KKA03244.1 - 1.2e-36 125.0 7.5 1.3e-36 124.8 7.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 KKA03244.1 - 0.0096 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain DUF505 PF04458.12 KKA03244.1 - 0.027 12.9 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) MarR_2 PF12802.7 KKA03244.1 - 0.11 12.4 0.3 0.2 11.6 0.3 1.5 1 1 0 1 1 1 0 MarR family Thg1 PF04446.12 KKA03245.1 - 1.2e-49 167.5 3.3 1.7e-49 167.0 3.3 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KKA03245.1 - 2.4e-37 127.8 0.7 3.8e-37 127.1 0.2 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain Peptidase_M13_N PF05649.13 KKA03245.1 - 0.0039 16.9 0.2 0.0048 16.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 TMEM208_SND2 PF05620.11 KKA03247.1 - 0.057 13.2 13.5 2.1 8.1 0.6 3.2 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF5643 PF18705.1 KKA03247.1 - 0.062 13.3 4.0 0.091 12.7 0.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Ras PF00071.22 KKA03248.1 - 3.5e-59 199.0 1.7 4.3e-59 198.7 1.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA03248.1 - 6.4e-36 123.2 1.3 6.8e-36 123.1 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA03248.1 - 7.6e-18 64.6 0.6 1.1e-17 64.0 0.6 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKA03248.1 - 2e-07 30.6 0.6 2.7e-07 30.2 0.6 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKA03248.1 - 1.4e-05 25.1 0.6 9.8e-05 22.4 0.1 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKA03248.1 - 3.1e-05 23.5 1.0 4.7e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKA03248.1 - 7.1e-05 22.8 2.0 0.12 12.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KKA03248.1 - 0.00013 21.5 1.1 0.00021 20.9 0.7 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KKA03248.1 - 0.0047 16.3 1.8 0.61 9.3 0.0 2.1 2 0 0 2 2 2 2 Septin PduV-EutP PF10662.9 KKA03248.1 - 0.008 15.9 0.9 1 9.1 0.9 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KKA03248.1 - 0.011 16.2 0.0 0.029 14.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKA03248.1 - 0.012 15.9 0.0 0.048 13.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain MACPF PF01823.19 KKA03248.1 - 0.014 15.5 2.3 0.015 15.4 2.3 1.2 1 0 0 1 1 1 0 MAC/Perforin domain ABC_tran PF00005.27 KKA03248.1 - 0.014 15.9 4.1 0.24 11.9 4.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KKA03248.1 - 0.027 14.0 0.2 0.058 12.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KKA03248.1 - 0.037 14.4 0.0 0.05 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KKA03248.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KKA03248.1 - 0.12 12.4 0.1 0.4 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) E1-E2_ATPase PF00122.20 KKA03249.1 - 1.8e-50 170.9 0.9 1.8e-50 170.9 0.9 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKA03249.1 - 2e-44 151.5 1.5 2e-44 151.5 1.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKA03249.1 - 1.4e-19 71.2 0.2 3.9e-19 69.8 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKA03249.1 - 1.4e-15 57.1 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKA03249.1 - 4.6e-13 48.6 0.0 1.2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKA03249.1 - 0.0039 16.9 0.9 0.0039 16.9 0.9 3.6 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Mid2 PF04478.12 KKA03250.1 - 1.8e-23 83.1 2.3 1.8e-23 83.1 2.3 3.1 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KKA03250.1 - 0.00032 20.0 2.8 0.00032 20.0 2.8 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain RIFIN PF02009.16 KKA03250.1 - 0.51 10.2 5.1 1.2 9.0 5.1 1.7 1 1 0 1 1 1 0 Rifin Orf78 PF06024.12 KKA03250.1 - 3.7 7.9 6.2 0.91 9.9 0.3 3.0 2 2 0 2 2 2 0 Orf78 (ac78) WH2 PF02205.20 KKA03251.1 - 1.3e-10 40.8 0.2 4.3e-10 39.1 0.3 1.8 2 0 0 2 2 2 1 WH2 motif Tubulin PF00091.25 KKA03252.1 - 3.9e-68 229.5 0.0 6.8e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKA03252.1 - 1.2e-41 141.8 0.0 1.9e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKA03252.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KKA03252.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KKA03252.1 - 0.056 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like RNA_pol PF00940.19 KKA03253.1 - 1.8e-150 501.4 0.1 3.2e-150 500.6 0.1 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KKA03253.1 - 8e-22 78.1 0.0 2.1e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA_synthFbeta PF17759.1 KKA03254.1 - 1.7e-44 151.8 0.0 2.5e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KKA03254.1 - 2.3e-29 102.3 0.1 4.1e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 KKA03254.1 - 3.4e-28 97.7 2.1 1.1e-25 89.7 0.4 2.9 2 1 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KKA03254.1 - 3.5e-15 56.1 0.0 2.1e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain Pkinase PF00069.25 KKA03255.1 - 3.2e-55 187.3 0.3 1.8e-34 119.3 0.5 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03255.1 - 7.1e-25 87.8 0.7 7.3e-21 74.6 0.2 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KKA03255.1 - 0.0001 22.4 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain APH PF01636.23 KKA03255.1 - 0.00018 21.5 0.5 0.0023 17.9 1.4 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKA03255.1 - 0.00022 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKA03255.1 - 0.0036 16.7 1.7 0.068 12.5 0.0 2.5 3 0 0 3 3 3 1 Kinase-like S4_2 PF13275.6 KKA03256.1 - 0.058 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 S4 domain Mis12 PF05859.12 KKA03257.1 - 6.3e-08 32.8 3.8 6.3e-08 32.8 3.8 2.1 1 1 1 2 2 2 1 Mis12 protein DUF1507 PF07408.11 KKA03257.1 - 0.0025 17.7 2.4 0.019 14.8 0.2 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1507) DUF5601 PF18151.1 KKA03257.1 - 0.42 10.9 3.9 3.3 8.1 0.6 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF5601) Thioredoxin_14 PF18402.1 KKA03258.1 - 6.5e-20 72.1 14.8 7.3e-17 62.2 6.7 5.2 3 2 1 4 4 4 1 Thioredoxin-like domain Glyco_transf_24 PF18404.1 KKA03258.1 - 1.7e-16 60.5 7.2 1.7e-16 60.5 7.2 2.5 3 0 0 3 3 3 1 Glucosyltransferase 24 CactinC_cactus PF09732.9 KKA03258.1 - 3.3 7.6 7.4 0.19 11.7 0.3 2.6 3 0 0 3 3 3 0 Cactus-binding C-terminus of cactin protein Fungal_trans PF04082.18 KKA03259.1 - 1.4e-30 106.2 5.1 1.4e-30 106.2 5.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA03259.1 - 3.3e-07 30.3 10.2 5.6e-07 29.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF624 PF04854.14 KKA03259.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Pox_A_type_inc PF04508.12 KKA03259.1 - 1.2 9.1 6.2 0.52 10.2 1.3 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat tRNA-synt_2c PF01411.19 KKA03260.1 - 9.4e-221 734.1 0.0 9.4e-221 734.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KKA03260.1 - 5.7e-19 67.9 0.2 1.4e-18 66.7 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KKA03260.1 - 3.2e-11 43.8 4.4 8.2e-11 42.5 4.4 1.8 1 0 0 1 1 1 1 DHHA1 domain Zn_clus PF00172.18 KKA03261.1 - 0.00018 21.5 8.1 0.00042 20.4 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.27 KKA03262.1 - 2.4e-33 115.3 0.0 8.1e-33 113.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKA03262.1 - 4e-21 75.1 0.0 1.6e-20 73.1 0.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KKA03262.1 - 2.4e-15 56.7 3.4 5.2e-11 42.8 0.2 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKA03262.1 - 8.6e-08 32.3 1.7 1.8e-06 28.0 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KKA03262.1 - 5.1e-06 26.3 0.1 2.4e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 4 FeoB_N PF02421.18 KKA03262.1 - 2.5e-05 23.8 0.1 0.00051 19.6 0.1 3.1 3 1 0 3 3 3 1 Ferrous iron transport protein B Roc PF08477.13 KKA03262.1 - 9.5e-05 22.6 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKA03262.1 - 0.015 14.9 0.0 0.2 11.3 0.0 2.6 1 1 1 2 2 2 0 Ras family CDC27 PF09507.10 KKA03262.1 - 1.9 7.8 13.9 3.2 7.0 13.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rib_recp_KP_reg PF05104.12 KKA03262.1 - 2.5 9.1 17.1 5.7 8.0 17.1 1.6 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region RNA_pol_Rpb1_5 PF04998.17 KKA03263.1 - 2.1e-99 332.3 0.1 4.6e-98 327.9 0.1 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKA03263.1 - 1.1e-69 234.0 0.5 2.6e-69 232.7 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKA03263.1 - 2.6e-37 128.2 5.9 5.2e-37 127.2 0.0 3.8 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KKA03263.1 - 5.6e-25 88.3 2.6 5.6e-25 88.3 2.6 3.3 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KKA03263.1 - 8.3e-23 80.4 0.5 3.8e-22 78.3 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 FtsX_ECD PF18075.1 KKA03263.1 - 0.27 11.9 3.6 9.5 6.9 0.1 2.9 2 0 0 2 2 2 0 FtsX extracellular domain DAO PF01266.24 KKA03264.1 - 6.7e-15 55.5 0.0 2.8e-10 40.3 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase RIH_assoc PF08454.11 KKA03264.1 - 0.095 12.6 0.4 0.27 11.1 0.1 1.9 1 1 0 1 1 1 0 RyR and IP3R Homology associated PPI_Ypi1 PF07491.11 KKA03265.1 - 3.2e-19 68.5 9.5 9.2e-19 67.0 9.5 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor RE_ApaLI PF09499.10 KKA03265.1 - 0.095 12.4 1.6 3.4 7.3 0.2 2.1 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease WBS_methylT PF12589.8 KKA03265.1 - 0.26 12.1 3.4 6.5 7.6 0.7 2.2 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome PseudoU_synth_1 PF01416.20 KKA03266.1 - 8e-30 103.5 0.0 5.9e-27 94.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase WSC PF01822.19 KKA03267.1 - 6.2e-09 35.9 11.3 6.2e-09 35.9 11.3 3.2 2 1 0 2 2 1 1 WSC domain SOG2 PF10428.9 KKA03267.1 - 9e-05 21.9 28.7 0.00011 21.6 28.7 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Vpu PF00558.19 KKA03267.1 - 0.0025 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Vpu protein Mid2 PF04478.12 KKA03267.1 - 0.014 15.3 1.5 0.014 15.3 1.5 4.0 1 1 3 4 4 4 0 Mid2 like cell wall stress sensor DUF4330 PF14221.6 KKA03267.1 - 0.029 14.6 5.1 0.045 14.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Holin_BhlA PF10960.8 KKA03267.1 - 0.035 14.1 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 BhlA holin family EphA2_TM PF14575.6 KKA03267.1 - 0.051 14.5 0.8 0.2 12.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 KKA03267.1 - 0.13 12.6 5.8 0.21 11.9 0.0 3.2 2 1 0 2 2 2 0 Orf78 (ac78) NPR3 PF03666.13 KKA03267.1 - 0.14 10.9 14.4 0.29 9.9 14.4 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hamartin PF04388.12 KKA03267.1 - 0.53 8.9 29.6 0.72 8.4 29.6 1.2 1 0 0 1 1 1 0 Hamartin protein Nop14 PF04147.12 KKA03267.1 - 0.87 7.7 14.2 1.4 7.1 14.2 1.3 1 0 0 1 1 1 0 Nop14-like family AAA PF00004.29 KKA03268.1 - 2.3e-95 316.0 0.0 1.1e-47 161.7 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA03268.1 - 2.8e-22 78.2 0.1 3.1e-10 39.7 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KKA03268.1 - 1.9e-16 60.2 0.0 4.3e-09 36.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKA03268.1 - 2.2e-12 47.7 0.3 0.0006 20.2 0.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain Vps4_C PF09336.10 KKA03268.1 - 1.4e-10 41.0 0.4 2.6e-06 27.3 0.2 2.8 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 KKA03268.1 - 1.5e-10 41.2 0.1 9.2e-05 22.5 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKA03268.1 - 1.6e-10 41.4 0.0 0.00031 20.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KKA03268.1 - 3.2e-10 40.3 0.0 0.00015 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKA03268.1 - 4.5e-10 39.9 0.3 0.0038 17.5 0.0 4.2 3 2 1 4 4 3 2 AAA domain ABC_tran PF00005.27 KKA03268.1 - 1.6e-08 35.2 0.4 0.0088 16.6 0.0 3.4 3 0 0 3 3 3 2 ABC transporter TIP49 PF06068.13 KKA03268.1 - 1.7e-08 34.1 5.6 0.00015 21.1 0.0 3.2 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 KKA03268.1 - 2.1e-08 34.7 0.2 0.0017 18.9 0.0 3.6 4 1 0 4 4 2 2 AAA domain AAA_14 PF13173.6 KKA03268.1 - 2.7e-08 33.9 0.0 0.0044 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKA03268.1 - 1.1e-07 32.1 0.0 0.014 15.8 0.0 3.3 2 1 0 2 2 2 2 RNA helicase Rad17 PF03215.15 KKA03268.1 - 2.3e-07 30.9 0.0 0.0016 18.4 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 KKA03268.1 - 4.4e-07 29.4 0.0 0.033 13.5 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_28 PF13521.6 KKA03268.1 - 1.2e-06 28.8 0.0 0.03 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KKA03268.1 - 1.6e-06 28.0 0.1 0.038 13.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKA03268.1 - 1.9e-06 27.5 0.2 0.044 13.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 KKA03268.1 - 2.4e-06 27.8 0.0 0.00048 20.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 KKA03268.1 - 3.4e-06 27.5 0.0 0.0093 16.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKA03268.1 - 4.7e-06 26.6 0.0 0.064 13.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKA03268.1 - 1.4e-05 25.1 0.1 0.087 12.7 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_3 PF07726.11 KKA03268.1 - 1.9e-05 24.5 0.0 0.088 12.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KKA03268.1 - 3.7e-05 23.6 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KKA03268.1 - 5.3e-05 22.5 2.1 0.16 11.2 0.0 3.6 5 0 0 5 5 3 2 NB-ARC domain SKI PF01202.22 KKA03268.1 - 7.3e-05 22.9 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activat PF00158.26 KKA03268.1 - 0.00012 21.8 0.0 0.23 11.2 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 KKA03268.1 - 0.00014 21.9 0.0 1.3 8.9 0.0 3.3 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KKA03268.1 - 0.00014 21.7 0.0 0.86 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KKA03268.1 - 0.00016 21.1 0.1 1.3 8.3 0.0 3.4 2 1 0 3 3 3 2 KaiC AAA_25 PF13481.6 KKA03268.1 - 0.00021 20.9 0.1 1.6 8.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KKA03268.1 - 0.00043 19.8 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region NTPase_1 PF03266.15 KKA03268.1 - 0.00044 20.2 0.1 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 NTPase Parvo_NS1 PF01057.17 KKA03268.1 - 0.00079 18.6 0.2 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KKA03268.1 - 0.0012 18.0 0.0 0.077 12.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KKA03268.1 - 0.0017 18.7 0.0 0.66 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KKA03268.1 - 0.0023 17.8 5.5 0.54 10.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.6 KKA03268.1 - 0.0028 17.8 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain CPT PF07931.12 KKA03268.1 - 0.003 17.4 0.0 0.073 12.9 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 KKA03268.1 - 0.0087 15.8 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AFG1_ATPase PF03969.16 KKA03268.1 - 0.015 14.2 0.0 3.5 6.4 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin PF02224.18 KKA03268.1 - 0.016 15.0 1.3 0.8 9.4 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase ATP-synt_ab PF00006.25 KKA03268.1 - 0.021 14.5 0.0 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KKA03268.1 - 0.021 14.5 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADK PF00406.22 KKA03268.1 - 0.022 14.9 1.2 1.4 9.0 0.0 2.9 3 0 0 3 3 2 0 Adenylate kinase PhoH PF02562.16 KKA03268.1 - 0.023 14.1 0.3 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 KKA03268.1 - 0.03 13.6 0.0 4.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KKA03268.1 - 0.034 13.9 0.1 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KKA03268.1 - 0.041 13.3 0.0 10 5.5 0.0 2.9 2 1 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 KKA03268.1 - 0.05 13.1 0.5 2.1 7.8 0.0 2.8 3 0 0 3 3 2 0 Ferrous iron transport protein B Hydin_ADK PF17213.3 KKA03268.1 - 0.068 13.4 2.1 1.9 8.7 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 KKA03268.1 - 0.073 12.1 0.0 0.91 8.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKA03268.1 - 0.082 12.8 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KKA03268.1 - 0.11 13.0 0.1 0.11 13.0 0.1 3.4 3 0 0 3 3 3 0 AAA domain YL1 PF05764.13 KKA03268.1 - 0.13 12.4 8.6 0.23 11.5 8.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein MMR_HSR1 PF01926.23 KKA03268.1 - 0.32 11.1 2.3 3.1 7.9 0.1 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase Bac_DnaA PF00308.18 KKA03268.1 - 1.2 8.9 6.5 3.6 7.4 0.0 3.7 4 2 0 4 4 2 0 Bacterial dnaA protein Fe-S_biosyn PF01521.20 KKA03269.1 - 6.5e-16 58.5 0.1 2.6e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis Sod_Cu PF00080.20 KKA03270.1 - 4.3e-17 62.6 0.0 7.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CorA PF01544.18 KKA03271.1 - 1.8e-07 30.8 11.3 3.9e-07 29.7 10.9 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 KKA03271.1 - 1.2 9.6 5.6 12 6.4 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4581 PF15167.6 KKA03272.1 - 0.058 13.5 0.3 2.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4581) Serglycin PF04360.12 KKA03273.1 - 1.2 9.1 5.6 0.26 11.2 0.8 2.0 1 1 1 2 2 2 0 Serglycin HEAT_EZ PF13513.6 KKA03274.1 - 1.7e-07 31.6 1.9 5.7e-05 23.5 0.0 5.6 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 KKA03274.1 - 2.7e-06 27.1 19.8 0.16 12.3 0.0 9.9 10 1 0 10 10 10 2 HEAT repeat IBN_N PF03810.19 KKA03274.1 - 6e-06 26.1 2.0 6e-06 26.1 2.0 3.4 3 1 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KKA03274.1 - 0.021 14.8 1.3 19 5.5 0.0 4.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 KKA03274.1 - 0.027 14.2 2.0 0.11 12.3 0.1 2.8 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) DCB PF16213.5 KKA03274.1 - 0.04 13.6 10.4 0.27 10.9 0.8 3.4 3 1 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 PAP2 PF01569.21 KKA03275.1 - 3e-14 52.9 0.8 5.5e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily V_ATPase_I PF01496.19 KKA03275.1 - 0.027 12.4 1.8 0.038 11.9 0.1 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC_2 PF13515.6 KKA03275.1 - 0.52 10.4 7.7 0.12 12.5 2.0 2.3 2 1 0 2 2 2 0 Fusaric acid resistance protein-like ESCRT-II PF05871.12 KKA03276.1 - 0.055 13.7 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 ESCRT-II complex subunit FBD PF08387.10 KKA03276.1 - 0.072 13.0 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 FBD Ras PF00071.22 KKA03278.1 - 1.2e-05 25.0 0.0 0.036 13.7 0.0 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKA03278.1 - 0.0049 17.1 0.0 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKA03278.1 - 0.0089 16.1 0.0 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF5040 PF16443.5 KKA03278.1 - 0.054 12.9 0.2 0.054 12.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5040) Syja_N PF02383.18 KKA03279.1 - 2.1e-72 244.2 5.8 2.1e-72 244.2 5.8 2.0 2 0 0 2 2 2 1 SacI homology domain DUF4990 PF16380.5 KKA03279.1 - 0.083 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF2408 PF10303.9 KKA03279.1 - 0.73 10.4 5.1 0.65 10.6 2.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Septin PF00735.18 KKA03280.1 - 2.2e-79 266.7 3.0 3.6e-79 266.0 3.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKA03280.1 - 0.00099 19.2 1.1 0.0019 18.3 0.4 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KKA03280.1 - 0.0026 18.3 0.0 0.0026 18.3 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 KKA03280.1 - 0.015 15.9 0.9 0.081 13.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKA03280.1 - 0.037 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KKA03280.1 - 0.039 13.5 1.7 0.15 11.6 0.4 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 KKA03280.1 - 0.14 11.4 0.2 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KKA03280.1 - 0.16 11.9 2.1 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase DUF676 PF05057.14 KKA03281.1 - 8.7e-44 149.6 0.3 8.7e-44 149.6 0.3 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKA03281.1 - 0.0039 16.9 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein FAD-oxidase_C PF02913.19 KKA03282.1 - 2.4e-49 168.2 0.0 3.5e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKA03282.1 - 7.4e-32 110.0 1.2 1.7e-31 108.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain TAFII28 PF04719.14 KKA03282.1 - 0.12 12.5 0.2 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 hTAFII28-like protein conserved region ZZ PF00569.17 KKA03283.1 - 1.6e-14 53.5 13.1 2.6e-14 52.7 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KKA03283.1 - 9.8e-11 41.7 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA03283.1 - 4.5e-06 26.8 0.1 1e-05 25.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KKA03283.1 - 7.6e-05 23.0 0.1 0.0006 20.1 0.0 2.5 2 0 0 2 2 2 1 SWIRM domain Toxin_13 PF07822.11 KKA03283.1 - 0.66 10.2 4.7 0.36 11.0 1.6 2.0 1 1 1 2 2 2 0 Neurotoxin B-IV-like protein U3_assoc_6 PF08640.11 KKA03284.1 - 2.4e-32 110.8 4.1 3.4e-30 103.9 1.1 2.8 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KKA03284.1 - 0.00047 20.8 0.0 1.4 10.0 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KKA03284.1 - 0.0016 17.7 9.4 0.029 13.5 0.1 3.1 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_11 PF13414.6 KKA03284.1 - 0.0057 16.3 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 1 TPR repeat LIM_bind PF01803.16 KKA03284.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 LIM-domain binding protein TPR_17 PF13431.6 KKA03284.1 - 0.026 14.9 1.9 22 5.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 KKA03284.1 - 0.25 11.3 12.5 0.046 13.7 5.2 3.0 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Tugs PF17840.1 KKA03284.1 - 0.28 11.4 1.9 0.41 10.9 0.7 1.9 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Bromodomain PF00439.25 KKA03284.1 - 0.66 10.1 4.9 8.3 6.6 0.4 3.2 3 1 0 3 3 3 0 Bromodomain DUF1642 PF07852.11 KKA03284.1 - 2.5 8.7 6.4 2.9 8.5 0.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) Homeodomain PF00046.29 KKA03285.1 - 1.5e-13 50.3 1.2 3.3e-13 49.3 1.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKA03285.1 - 1.8e-05 24.6 0.2 4.4e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KKA03285.1 - 0.0023 17.3 0.1 0.0057 16.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Arylsulfotran_N PF17425.2 KKA03286.1 - 0.012 15.6 1.5 0.028 14.4 1.5 1.6 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain Peptidase_M41 PF01434.18 KKA03286.1 - 4 7.2 4.8 0.71 9.7 1.0 1.6 2 0 0 2 2 2 0 Peptidase family M41 OST3_OST6 PF04756.13 KKA03288.1 - 1.5e-13 50.8 14.9 6.9e-13 48.6 13.1 2.6 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family TctB PF07331.11 KKA03288.1 - 0.024 14.9 1.2 0.74 10.1 1.9 2.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF898 PF05987.13 KKA03288.1 - 0.054 12.6 3.6 0.93 8.5 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF2269 PF10027.9 KKA03288.1 - 0.069 13.2 0.8 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) AgrB PF04647.15 KKA03288.1 - 0.64 9.3 18.2 0.99 8.7 6.6 2.6 2 0 0 2 2 2 0 Accessory gene regulator B DUF4064 PF13273.6 KKA03288.1 - 5.9 7.2 16.4 2.4 8.5 1.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) DUF4357 PF14267.6 KKA03289.1 - 0.34 10.9 4.1 0.13 12.3 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) PIG-P PF08510.12 KKA03290.1 - 3.7e-14 52.7 7.8 5e-14 52.3 7.8 1.1 1 0 0 1 1 1 1 PIG-P Tmpp129 PF10272.9 KKA03290.1 - 0.0049 16.2 1.7 0.0057 16.0 1.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein precursor TraS PF10624.9 KKA03290.1 - 0.1 12.5 2.4 0.13 12.2 2.4 1.1 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Metallophos PF00149.28 KKA03291.1 - 3.7e-37 128.8 0.1 9.7e-37 127.4 0.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKA03291.1 - 6.7e-14 52.1 0.0 1.5e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain FidL_like PF15941.5 KKA03292.1 - 4.5 7.8 10.0 0.19 12.2 1.5 3.1 3 1 1 4 4 4 0 FidL-like putative membrane protein DUF1351 PF07083.11 KKA03293.1 - 0.15 11.8 10.8 0.36 10.6 10.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) Coleoptericin PF06286.11 KKA03293.1 - 0.29 11.2 2.4 0.26 11.4 0.3 2.0 2 0 0 2 2 2 0 Coleoptericin ABC_tran PF00005.27 KKA03294.1 - 6.9e-49 165.9 0.1 3.9e-24 85.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KKA03294.1 - 5.1e-21 74.5 3.7 5.1e-21 74.5 3.7 3.6 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KKA03294.1 - 1.9e-16 60.8 6.6 0.00032 20.6 0.0 4.3 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKA03294.1 - 9.1e-09 35.4 0.7 2e-05 24.6 0.0 3.5 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KKA03294.1 - 5.3e-08 33.4 0.0 0.0014 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KKA03294.1 - 1.3e-07 31.2 0.0 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KKA03294.1 - 2.5e-07 31.3 0.1 0.0086 16.6 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KKA03294.1 - 3.5e-07 30.3 0.1 0.039 13.6 0.0 3.4 2 2 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 KKA03294.1 - 6.2e-07 29.1 1.0 0.6 9.5 0.0 4.5 3 1 2 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KKA03294.1 - 8e-07 29.4 0.0 0.0097 16.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KKA03294.1 - 1e-06 29.2 0.1 0.043 14.2 0.0 3.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KKA03294.1 - 1.2e-06 28.6 0.7 0.0034 17.5 0.0 3.5 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKA03294.1 - 1.5e-06 28.5 0.0 0.0032 17.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KKA03294.1 - 3.1e-06 27.3 0.8 0.37 10.8 0.0 3.6 2 1 1 3 3 3 2 Dynamin family AAA_33 PF13671.6 KKA03294.1 - 5.3e-06 26.6 0.5 0.037 14.2 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_14 PF13173.6 KKA03294.1 - 5.7e-06 26.4 0.0 0.098 12.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KKA03294.1 - 1.2e-05 25.3 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KKA03294.1 - 3e-05 24.4 0.1 0.19 12.1 0.0 3.2 3 0 0 3 3 3 2 RNA helicase NB-ARC PF00931.22 KKA03294.1 - 8.7e-05 21.8 0.0 0.19 10.9 0.0 3.2 2 1 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.6 KKA03294.1 - 0.00012 22.6 15.2 0.049 14.1 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA_5 PF07728.14 KKA03294.1 - 0.00023 21.2 0.1 1.8 8.5 0.1 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KKA03294.1 - 0.0005 19.8 0.5 0.3 10.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain MCM PF00493.23 KKA03294.1 - 0.00058 19.0 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain Rad17 PF03215.15 KKA03294.1 - 0.00089 19.2 0.0 0.58 10.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 KKA03294.1 - 0.0017 17.5 0.1 1.1 8.3 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_27 PF13514.6 KKA03294.1 - 0.0021 17.7 0.0 0.9 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKA03294.1 - 0.003 17.2 0.2 1.1 8.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 KKA03294.1 - 0.0033 17.6 0.0 0.57 10.4 0.0 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KKA03294.1 - 0.0065 16.0 0.1 0.15 11.5 0.0 2.4 3 0 0 3 3 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KKA03294.1 - 0.0065 16.4 0.0 0.41 10.5 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KKA03294.1 - 0.008 15.9 0.0 1.7 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKA03294.1 - 0.0083 16.1 0.1 1.2 9.2 0.0 2.8 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 KKA03294.1 - 0.0087 15.3 0.1 0.73 8.9 0.0 2.6 2 1 0 2 2 2 1 G-protein alpha subunit ATPase_2 PF01637.18 KKA03294.1 - 0.011 15.7 4.1 0.57 10.1 0.0 3.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea MeaB PF03308.16 KKA03294.1 - 0.012 14.6 0.1 2.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KKA03294.1 - 0.018 14.8 0.2 7 6.4 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KKA03294.1 - 0.019 14.5 0.0 0.58 9.7 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B EcoEI_R_C PF08463.10 KKA03294.1 - 0.026 14.6 1.3 2 8.5 0.1 2.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal PRK PF00485.18 KKA03294.1 - 0.028 14.2 0.0 0.27 10.9 0.0 2.4 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KKA03294.1 - 0.066 13.6 6.8 0.55 10.7 0.0 3.3 4 0 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.17 KKA03294.1 - 0.072 12.9 0.2 25 4.5 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KKA03294.1 - 0.39 10.8 6.9 11 6.0 0.0 3.8 4 1 1 5 5 3 0 Helicase HerA, central domain SRP54 PF00448.22 KKA03294.1 - 3.1 7.4 6.0 5.4 6.6 0.0 3.4 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Xan_ur_permease PF00860.20 KKA03295.1 - 2.5e-55 187.8 31.8 4e-55 187.1 31.8 1.3 1 0 0 1 1 1 1 Permease family Phage_holin_2_4 PF16082.5 KKA03295.1 - 0.016 14.9 0.3 0.21 11.4 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like CHZ PF09649.10 KKA03296.1 - 1.6e-05 24.3 0.4 1.6e-05 24.3 0.4 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ Kinesin PF00225.23 KKA03297.1 - 3.5e-69 233.3 4.8 8.2e-69 232.1 4.8 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKA03297.1 - 9.6e-08 32.1 0.4 9.6e-08 32.1 0.4 3.1 2 1 0 2 2 2 1 Microtubule binding AAA PF00004.29 KKA03297.1 - 0.027 14.9 0.0 0.091 13.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BRCA-2_OB1 PF09103.10 KKA03297.1 - 0.036 14.0 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 AAA_22 PF13401.6 KKA03297.1 - 0.041 14.1 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKA03297.1 - 0.23 11.9 3.1 0.76 10.2 0.0 3.4 3 1 1 4 4 4 0 RNA helicase SAPS PF04499.15 KKA03298.1 - 4.1e-140 467.8 17.4 4.1e-140 467.8 17.4 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DnaJ PF00226.31 KKA03299.1 - 2.4e-09 37.2 6.5 5.1e-09 36.1 6.5 1.6 1 0 0 1 1 1 1 DnaJ domain Swi6_N PF18530.1 KKA03299.1 - 0.093 12.9 1.4 0.13 12.4 0.1 1.9 2 1 0 2 2 2 0 Swi6 N-terminal domain DUF573 PF04504.14 KKA03299.1 - 0.3 11.8 9.0 1.1 10.0 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 NIF3 PF01784.18 KKA03301.1 - 1e-63 215.2 0.4 1.3e-63 214.9 0.4 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF1077 PF06417.12 KKA03303.1 - 4.9e-09 36.2 1.0 6.9e-09 35.7 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF5364 PF17322.2 KKA03304.1 - 0.00073 19.9 32.9 0.0031 17.9 32.9 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5364) Peptidase_M20 PF01546.28 KKA03305.1 - 2.4e-29 102.5 0.0 3.7e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKA03305.1 - 2.7e-10 40.1 0.0 4.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKA03305.1 - 5.6e-05 22.9 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Sec15 PF04091.12 KKA03306.1 - 8.4e-72 242.2 14.1 8.4e-72 242.2 14.1 2.5 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like KinB_sensor PF16767.5 KKA03306.1 - 0.36 11.3 3.7 1.2 9.6 0.5 3.2 2 1 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB PX PF00787.24 KKA03308.1 - 6.5e-12 45.4 2.0 6.5e-12 45.4 2.0 2.5 3 0 0 3 3 3 1 PX domain SNARE PF05739.19 KKA03308.1 - 0.025 14.5 0.7 0.025 14.5 0.7 2.4 3 0 0 3 3 3 0 SNARE domain zn-ribbon_14 PF16503.5 KKA03309.1 - 4.3e-18 64.5 3.6 4.3e-18 64.5 3.6 2.9 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 KKA03309.1 - 2e-17 63.5 0.0 4.9e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 KKA03309.1 - 0.0085 14.9 0.0 0.021 13.6 0.0 1.6 1 1 0 1 1 1 1 tRNA methyl transferase CTU2 PF10288.9 KKA03309.1 - 0.81 9.9 4.4 0.52 10.6 0.2 2.4 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 WD40 PF00400.32 KKA03310.1 - 2.1e-07 31.5 3.8 0.3 12.0 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2757 PF10955.8 KKA03310.1 - 0.082 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) zinc_ribbon_13 PF09855.9 KKA03310.1 - 0.099 12.8 1.5 0.63 10.3 0.0 2.8 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Cyclin PF08613.11 KKA03311.1 - 2.5e-09 37.7 0.4 2.5e-09 37.7 0.4 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KKA03311.1 - 2e-07 30.8 0.0 2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Orn_DAP_Arg_deC PF00278.22 KKA03311.1 - 0.35 11.1 1.9 0.43 10.8 0.0 2.1 2 1 0 2 2 2 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-C2H2 PF00096.26 KKA03312.1 - 1.7e-05 25.0 20.2 0.02 15.3 6.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA03312.1 - 8.6e-05 22.8 5.4 8.6e-05 22.8 5.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA03312.1 - 0.0015 19.2 17.0 0.069 14.0 4.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KKA03312.1 - 6.1 6.6 7.7 0.65 9.7 2.8 2.0 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain RNA_Me_trans PF04252.13 KKA03313.1 - 5.4e-65 218.7 0.0 6.1e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase CagD PF16567.5 KKA03313.1 - 0.04 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Cpn10 PF00166.21 KKA03314.1 - 7.6e-08 32.3 1.6 1.2e-07 31.6 1.6 1.3 1 1 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.10 KKA03315.1 - 7e-19 68.5 17.7 1.2e-18 67.7 17.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KKA03315.1 - 3.9e-06 27.0 0.1 3.9e-06 27.0 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) Ycf54 PF10674.9 KKA03315.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2488) DUF3502 PF12010.8 KKA03316.1 - 0.19 12.4 3.1 0.67 10.6 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Cyc-maltodext_C PF10438.9 KKA03316.1 - 3.6 7.7 6.6 8.2 6.6 1.6 3.2 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Lon_2 PF13337.6 KKA03317.1 - 0.014 13.9 0.7 0.021 13.4 0.7 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Rab5ip PF07019.12 KKA03317.1 - 0.029 15.0 0.6 0.1 13.2 0.5 1.9 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) DUF2470 PF10615.9 KKA03317.1 - 0.073 13.7 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) MatE PF01554.18 KKA03319.1 - 1.8e-45 154.5 38.4 2.2e-27 95.7 10.0 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KKA03319.1 - 7.2e-09 35.8 14.4 7.2e-09 35.8 14.4 3.9 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain FAM176 PF14851.6 KKA03319.1 - 0.1 12.3 0.1 0.1 12.3 0.1 3.1 3 0 0 3 3 3 0 FAM176 family LRIF1 PF15741.5 KKA03319.1 - 0.27 9.7 6.8 0.42 9.1 6.8 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 ATP19 PF11022.8 KKA03320.1 - 0.4 11.1 1.9 1.1 9.6 1.9 2.0 1 1 0 1 1 1 0 ATP synthase subunit K AAA_2 PF07724.14 KKA03321.1 - 1.5e-47 161.9 0.2 2e-46 158.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKA03321.1 - 1.5e-29 101.9 0.9 1.5e-29 101.9 0.9 3.8 4 0 0 4 4 4 1 AAA lid domain ClpB_D2-small PF10431.9 KKA03321.1 - 5.9e-26 90.3 0.9 2.3e-25 88.5 0.9 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KKA03321.1 - 3.7e-20 72.7 0.3 3.3e-11 43.7 0.2 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKA03321.1 - 2.3e-13 50.3 1.9 7.1e-10 39.0 0.0 4.1 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KKA03321.1 - 8.9e-10 38.7 0.1 0.00077 19.5 0.0 3.4 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KKA03321.1 - 1e-08 35.7 0.7 0.015 15.7 0.0 3.5 2 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KKA03321.1 - 2.6e-08 33.7 0.1 9.5e-06 25.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KKA03321.1 - 3.6e-08 33.8 2.4 0.0032 17.7 0.1 3.8 3 2 0 3 3 2 2 AAA domain TniB PF05621.11 KKA03321.1 - 2.3e-07 30.4 1.1 0.00062 19.2 0.3 4.2 3 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 KKA03321.1 - 3e-06 26.9 0.0 0.074 12.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 KKA03321.1 - 6.7e-05 22.9 0.0 0.026 14.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KKA03321.1 - 7.5e-05 22.5 0.0 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KKA03321.1 - 0.0001 22.7 2.4 0.65 10.4 0.1 3.9 3 1 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 KKA03321.1 - 0.00013 21.4 0.1 0.15 11.4 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KKA03321.1 - 0.00013 22.5 4.2 0.076 13.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter T2SSE PF00437.20 KKA03321.1 - 0.00029 20.0 0.0 0.43 9.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.6 KKA03321.1 - 0.00039 20.2 0.0 0.0072 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KKA03321.1 - 0.00044 20.2 0.5 0.23 11.4 0.0 3.2 3 0 0 3 3 2 1 NTPase RsgA_GTPase PF03193.16 KKA03321.1 - 0.00053 19.9 0.1 0.44 10.4 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 KKA03321.1 - 0.0006 19.8 8.8 1.2 9.0 0.1 4.3 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KKA03321.1 - 0.0028 17.0 0.5 0.66 9.2 0.0 4.0 4 1 1 5 5 5 1 Zeta toxin AAA_25 PF13481.6 KKA03321.1 - 0.0035 16.9 0.0 0.063 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKA03321.1 - 0.0036 17.8 4.2 0.69 10.5 0.1 4.3 3 1 1 4 4 4 1 AAA domain AAA_28 PF13521.6 KKA03321.1 - 0.0037 17.5 0.0 0.34 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KKA03321.1 - 0.0059 16.3 1.3 1.9 8.1 0.0 3.3 4 0 0 4 4 3 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KKA03321.1 - 0.0065 16.2 0.0 4 7.1 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 KKA03321.1 - 0.026 14.7 0.4 6.4 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 KKA03321.1 - 0.028 14.1 0.6 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KKA03321.1 - 0.036 14.4 1.3 0.37 11.1 0.4 3.0 3 1 0 4 4 3 0 AAA domain TsaE PF02367.17 KKA03321.1 - 0.038 14.0 0.1 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KKA03321.1 - 0.055 12.9 0.1 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein AAA_11 PF13086.6 KKA03321.1 - 0.18 11.5 3.7 1.8 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF4404 PF14357.6 KKA03321.1 - 0.29 11.8 3.8 1.9 9.2 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) ResIII PF04851.15 KKA03321.1 - 0.4 10.7 4.6 37 4.3 0.1 4.0 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit RhoGEF PF00621.20 KKA03323.1 - 5.9e-06 26.6 16.1 5.9e-06 26.6 16.1 4.1 3 2 0 4 4 4 1 RhoGEF domain Cas_APE2256 PF09651.10 KKA03323.1 - 1.2 9.0 4.2 45 3.9 0.1 3.7 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_APE2256) SBDS PF01172.18 KKA03324.1 - 6.2e-09 35.8 0.6 8.3e-09 35.4 0.6 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF2_N PF00176.23 KKA03325.1 - 6.4e-66 222.4 0.3 2.2e-65 220.7 0.3 2.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA03325.1 - 1.8e-19 70.1 0.5 1.8e-18 66.9 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA03325.1 - 1.3e-06 28.3 0.1 3.9e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.13 KKA03325.1 - 2.7e-06 27.6 12.7 7.2e-06 26.2 4.6 3.1 1 1 1 2 2 2 2 HSA AAA_25 PF13481.6 KKA03325.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KKA03326.1 - 3.1e-73 246.4 0.1 5.6e-73 245.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 KKA03326.1 - 1.9e-44 150.8 0.2 7.8e-44 148.9 0.1 2.1 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 KKA03326.1 - 1.3e-37 129.5 0.0 2.2e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA03326.1 - 5.5e-09 35.8 0.0 8.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 KKA03326.1 - 7.9e-05 22.7 0.4 0.00034 20.7 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kdo PF06293.14 KKA03326.1 - 0.0013 18.2 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKA03326.1 - 0.0026 16.7 1.3 0.0026 16.7 1.3 2.3 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KKA03326.1 - 0.12 12.2 0.1 0.37 10.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KKA03326.1 - 0.4 10.3 2.9 0.86 9.2 0.1 2.5 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SwrA PF17423.2 KKA03326.1 - 0.57 10.2 5.6 9 6.3 0.1 3.5 2 1 0 2 2 2 0 Swarming motility protein TPR_2 PF07719.17 KKA03327.1 - 9.7e-29 97.2 15.5 0.00021 21.1 0.3 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KKA03327.1 - 1.9e-28 97.1 22.7 9.6e-05 22.0 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KKA03327.1 - 2.8e-21 73.9 21.0 1.7e-05 24.6 0.2 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKA03327.1 - 2e-19 69.6 11.7 2.4e-09 37.3 0.2 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKA03327.1 - 5.9e-18 65.1 14.6 2.5e-06 27.9 0.1 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKA03327.1 - 7.8e-18 63.7 2.6 0.0017 19.0 0.2 7.8 5 2 3 8 8 8 3 Tetratricopeptide repeat STI1 PF17830.1 KKA03327.1 - 1.8e-17 63.0 9.2 3.1e-13 49.4 0.7 3.4 2 1 1 3 3 3 2 STI1 domain TPR_16 PF13432.6 KKA03327.1 - 2.5e-14 53.6 4.7 6.3e-05 23.5 1.7 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKA03327.1 - 2.4e-13 49.5 15.5 0.14 11.8 0.6 7.2 7 0 0 7 7 7 5 TPR repeat TPR_7 PF13176.6 KKA03327.1 - 1.9e-12 46.3 7.6 0.0047 16.9 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKA03327.1 - 9.2e-11 41.3 9.1 0.023 14.5 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKA03327.1 - 1.4e-10 40.8 6.3 0.97 10.0 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KKA03327.1 - 2.8e-06 26.9 0.0 4e-05 23.2 0.0 2.4 3 0 0 3 3 2 1 MalT-like TPR region TPR_6 PF13174.6 KKA03327.1 - 8e-06 26.2 19.7 0.29 11.9 0.2 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA03327.1 - 1.2e-05 25.5 16.2 0.017 15.4 1.5 5.0 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 KKA03327.1 - 4.9e-05 22.9 11.7 0.0051 16.3 0.4 4.5 3 2 1 5 5 5 2 Meiosis protein SPO22/ZIP4 like BTAD PF03704.17 KKA03327.1 - 0.0005 20.5 1.2 0.19 12.2 0.2 4.2 3 2 0 3 3 2 1 Bacterial transcriptional activator domain PPR PF01535.20 KKA03327.1 - 0.00095 19.3 1.7 8.9 6.8 0.0 4.9 6 0 0 6 6 4 0 PPR repeat Clathrin PF00637.20 KKA03327.1 - 0.0045 16.9 2.1 0.014 15.2 0.4 2.8 1 1 1 2 2 2 1 Region in Clathrin and VPS Wzy_C_2 PF11846.8 KKA03327.1 - 0.012 15.5 1.1 3.9 7.4 0.2 2.6 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 KKA03327.1 - 0.023 14.9 0.4 15 5.9 0.2 4.4 4 2 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KKA03327.1 - 0.028 14.5 26.2 0.22 11.6 0.4 7.0 6 2 2 8 8 7 0 MIT (microtubule interacting and transport) domain DUF1266 PF06889.11 KKA03327.1 - 0.093 12.8 0.7 0.23 11.5 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) ANAPC5 PF12862.7 KKA03327.1 - 0.1 12.7 2.8 0.56 10.3 0.5 3.4 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 TOM20_plant PF06552.12 KKA03327.1 - 1.1 9.0 7.6 0.98 9.1 0.1 3.8 2 2 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 KKA03327.1 - 1.1 9.4 16.0 2.4 8.3 0.1 5.5 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KKA03327.1 - 1.4 9.0 17.1 4.8 7.3 0.2 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKA03327.1 - 2.8 8.3 7.5 4.4 7.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SNF5 PF04855.12 KKA03328.1 - 8.1e-17 61.8 11.4 1.2e-10 41.6 0.1 2.8 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 Pkinase PF00069.25 KKA03330.1 - 8e-40 136.9 1.6 3.4e-39 134.8 1.6 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03330.1 - 1.6e-22 80.1 0.0 3.9e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA03330.1 - 0.01 15.2 0.0 0.055 12.8 0.0 2.3 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 KKA03330.1 - 0.013 14.9 3.0 0.037 13.4 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C13 PF01650.18 KKA03331.1 - 1.3e-43 149.3 5.8 1.8e-43 148.9 5.8 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF4976 PF16347.5 KKA03331.1 - 0.15 12.3 3.4 0.38 11.0 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) UBA_4 PF14555.6 KKA03332.1 - 4.8e-13 48.7 0.1 9.6e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 KKA03332.1 - 3.5e-09 36.7 0.0 8.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KKA03332.1 - 0.0023 18.1 0.0 0.006 16.8 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 KKA03332.1 - 0.0082 16.6 0.5 0.087 13.3 0.1 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain STE PF02200.16 KKA03333.1 - 9.2e-51 170.9 3.6 9.2e-51 170.9 3.6 1.9 2 0 0 2 2 2 1 STE like transcription factor Tcf25 PF04910.14 KKA03334.1 - 2.7e-29 102.3 9.9 5e-29 101.5 9.9 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Ipi1_N PF12333.8 KKA03335.1 - 1.5e-08 35.2 0.7 1.5e-08 35.2 0.7 2.5 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation PRF PF06875.11 KKA03336.1 - 0.0088 15.5 0.3 0.016 14.7 0.1 1.5 1 1 1 2 2 2 1 Plethodontid receptivity factor PRF Methyltransf_12 PF08242.12 KKA03336.1 - 0.037 14.8 0.1 0.93 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Rpr2 PF04032.16 KKA03337.1 - 0.017 15.4 0.2 0.017 15.4 0.2 2.9 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2387 PF09526.10 KKA03337.1 - 0.088 13.0 2.9 0.086 13.0 1.3 1.8 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Pex24p PF06398.11 KKA03338.1 - 3.1e-26 92.3 26.9 1.8e-24 86.4 20.6 2.2 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin Circo_capsid PF02443.15 KKA03339.1 - 0.035 13.7 2.3 0.25 10.9 1.1 2.3 2 0 0 2 2 2 0 Circovirus capsid protein Nsp3_PL2pro PF12124.8 KKA03340.1 - 0.096 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain O-ag_pol_Wzy PF14296.6 KKA03340.1 - 0.098 11.3 0.1 0.098 11.3 0.1 2.1 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF5345 PF17280.2 KKA03340.1 - 0.25 11.3 2.5 0.33 11.0 0.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Skp1 PF01466.19 KKA03341.1 - 1.8e-20 72.8 0.4 1.8e-20 72.8 0.4 2.3 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KKA03341.1 - 1.6e-07 31.4 11.4 9.4e-06 25.7 0.6 3.5 3 2 2 5 5 5 2 Skp1 family, tetramerisation domain RasGEF_N PF00618.20 KKA03341.1 - 0.038 14.2 0.3 0.071 13.4 0.3 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif DUF4375 PF14300.6 KKA03341.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) VASt PF16016.5 KKA03342.1 - 7.8e-25 88.1 0.2 2.3e-24 86.6 0.2 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KKA03342.1 - 1.3e-14 54.1 1.7 1.8e-14 53.5 0.4 2.0 2 0 0 2 2 2 1 GRAM domain DUF1891 PF09004.10 KKA03342.1 - 0.018 14.6 0.8 0.048 13.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) DUF155 PF02582.14 KKA03343.1 - 2.6e-47 161.2 0.1 2.6e-47 161.2 0.1 2.0 2 1 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF3876 PF12992.7 KKA03343.1 - 0.0049 16.9 0.7 0.81 9.8 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function, B. Theta Gene description (DUF3876) tRNA-synt_1c PF00749.21 KKA03344.1 - 1.8e-116 388.4 0.5 3.3e-116 387.6 0.5 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKA03344.1 - 1.6e-38 132.3 0.5 3.5e-38 131.2 0.5 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain YopX PF09643.10 KKA03344.1 - 0.36 10.9 3.7 0.73 9.9 1.8 2.6 2 1 1 3 3 3 0 YopX protein RAI1 PF08652.11 KKA03345.1 - 0.0022 18.2 3.6 0.0022 18.1 0.0 2.7 3 0 0 3 3 3 1 RAI1 like PD-(D/E)XK nuclease NCBP3 PF10309.9 KKA03345.1 - 0.15 11.9 3.6 0.71 9.8 0.0 3.2 3 0 0 3 3 3 0 Nuclear cap-binding protein subunit 3 Aldo_ket_red PF00248.21 KKA03346.1 - 2.3e-44 151.8 0.2 5.1e-44 150.6 0.2 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family AcetylCoA_hydro PF02550.15 KKA03346.1 - 0.0056 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain HemN_C PF06969.16 KKA03346.1 - 0.078 13.1 0.0 0.71 10.0 0.0 2.5 3 0 0 3 3 3 0 HemN C-terminal domain DUF5126 PF17166.4 KKA03346.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) S36_mt PF10937.8 KKA03347.1 - 7.7e-16 59.7 0.1 9.5e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial PDEase_II PF02112.15 KKA03348.1 - 2.2e-37 129.0 14.9 2.6e-37 128.7 14.9 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KKA03348.1 - 0.0081 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Proteasome PF00227.26 KKA03349.1 - 1.8e-29 102.6 0.0 2.6e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2505 PF10698.9 KKA03349.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Adap_comp_sub PF00928.21 KKA03350.1 - 3.3e-09 36.5 1.8 5.6e-09 35.8 1.8 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKA03350.1 - 0.0021 18.0 2.3 0.008 16.1 2.3 2.1 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Fibrinogen_BP PF08017.11 KKA03350.1 - 0.028 12.9 2.1 0.074 11.5 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen binding protein DUF2420 PF10336.9 KKA03351.1 - 3.6e-20 72.0 5.4 3.6e-20 72.0 5.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Ppx-GppA PF02541.16 KKA03352.1 - 2.4e-49 168.3 0.0 3.1e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family CSN8_PSD8_EIF3K PF10075.9 KKA03353.1 - 5.3e-08 33.0 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GIDA PF01134.22 KKA03354.1 - 9.6e-126 420.0 2.0 2.6e-125 418.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KKA03354.1 - 6.9e-56 189.7 0.6 1.2e-55 188.9 0.6 1.4 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KKA03354.1 - 0.014 14.7 1.9 0.19 10.9 1.8 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BSD PF03909.17 KKA03354.1 - 0.11 12.5 0.3 5.1 7.2 0.0 3.5 3 0 0 3 3 3 0 BSD domain AlaDh_PNT_C PF01262.21 KKA03354.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KKA03354.1 - 0.13 10.9 0.1 10 4.7 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein CDC4_D PF16856.5 KKA03355.1 - 0.0052 16.6 4.2 0.0052 16.6 4.2 2.8 3 0 0 3 3 3 1 Cell division control protein 4 dimerisation domain Biotin_carb_C PF02785.19 KKA03355.1 - 0.0082 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Glu-tRNAGln PF02686.15 KKA03355.1 - 0.13 12.6 1.7 3.5 8.0 0.0 3.1 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF836 PF05768.14 KKA03355.1 - 0.16 12.4 7.0 0.5 10.8 2.7 3.3 1 1 2 3 3 3 0 Glutaredoxin-like domain (DUF836) Carbam_trans_C PF16861.5 KKA03357.1 - 0.2 11.2 0.1 0.36 10.4 0.0 1.5 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus IBN_N PF03810.19 KKA03358.1 - 5.1e-05 23.1 3.0 0.00018 21.4 0.1 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain CBFB_NFYA PF02045.15 KKA03359.1 - 6.1e-21 74.8 5.0 1.2e-20 73.9 5.0 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TMEM70 PF06979.12 KKA03359.1 - 0.052 14.0 0.2 0.083 13.3 0.2 1.3 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex Cse1 PF08506.10 KKA03360.1 - 1.6e-135 451.7 12.9 1.6e-135 451.7 12.9 1.7 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 KKA03360.1 - 4.2e-80 269.4 14.9 4.2e-80 269.4 14.9 2.6 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus IBN_N PF03810.19 KKA03360.1 - 1.5e-09 37.7 0.3 2.1e-08 33.9 0.4 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KKA03360.1 - 8.8e-05 22.6 0.6 8.8e-05 22.6 0.6 3.7 3 1 0 3 3 3 1 Exportin 1-like protein ANAPC10 PF03256.16 KKA03361.1 - 6.2e-25 87.9 0.1 9.3e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KKA03361.1 - 0.0031 17.6 0.2 0.016 15.3 0.0 2.3 1 1 0 1 1 1 1 F5/8 type C domain Clathrin PF00637.20 KKA03362.1 - 3.4e-173 568.4 53.1 4.6e-31 107.6 0.2 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KKA03362.1 - 6.6e-22 77.2 0.1 4.6e-21 74.5 0.0 2.6 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 KKA03362.1 - 8.8e-11 41.6 4.7 0.00058 20.1 0.1 5.6 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 KKA03362.1 - 3.3e-10 39.1 0.3 1.2e-09 37.4 0.3 2.1 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KKA03362.1 - 3.4e-06 26.4 11.3 0.028 13.5 0.1 5.7 6 1 1 7 7 7 2 Coatomer WD associated region TPR_7 PF13176.6 KKA03362.1 - 0.0013 18.6 4.2 5.7 7.2 0.1 6.0 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKA03362.1 - 0.0014 19.3 0.0 31 5.7 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKA03362.1 - 0.071 13.4 11.8 8.2 6.9 0.0 7.7 7 1 1 8 8 8 0 Tetratricopeptide repeat NB PF04159.13 KKA03362.1 - 0.14 12.2 0.1 0.43 10.6 0.1 1.7 1 0 0 1 1 1 0 NB glycoprotein TPR_1 PF00515.28 KKA03362.1 - 0.26 11.2 12.4 2.8 7.9 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKA03362.1 - 0.54 10.5 14.6 4.8 7.6 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKA03362.1 - 1.3 9.4 4.5 3.9 7.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SPT16 PF08644.11 KKA03363.1 - 7.7e-48 162.5 0.5 7.7e-48 162.5 0.5 3.2 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KKA03363.1 - 4.1e-38 130.7 0.1 4.1e-38 130.7 0.1 4.0 3 1 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KKA03363.1 - 1.3e-26 93.6 0.0 2.1e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KKA03363.1 - 3.4e-13 49.8 0.1 1.6e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 KKA03363.1 - 7.1e-05 23.1 0.2 0.00072 19.8 0.0 2.4 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain AMPK1_CBM PF16561.5 KKA03364.1 - 6.1e-29 100.1 1.2 1.3e-28 99.0 0.1 2.2 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KKA03364.1 - 2.2e-26 91.9 5.5 2.2e-26 91.9 5.5 2.4 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain PAS_10 PF13596.6 KKA03364.1 - 0.15 12.6 1.7 0.69 10.5 0.2 2.5 2 0 0 2 2 2 0 PAS domain DDHD PF02862.17 KKA03366.1 - 1.5e-31 110.3 2.0 5.4e-20 72.5 0.3 2.5 1 1 1 2 2 2 2 DDHD domain DUF676 PF05057.14 KKA03366.1 - 0.0022 17.5 0.7 0.15 11.5 0.1 3.2 2 1 1 3 3 3 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKA03366.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 KKA03366.1 - 0.046 12.9 0.0 0.046 12.9 0.0 2.5 3 0 0 3 3 3 0 Lecithin:cholesterol acyltransferase TPR_19 PF14559.6 KKA03367.1 - 0.026 15.0 1.3 0.17 12.5 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKA03367.1 - 0.2 12.0 1.7 0.42 11.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ING PF12998.7 KKA03368.1 - 3.4e-07 30.8 5.4 7.7e-07 29.6 5.4 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKA03368.1 - 1e-05 25.4 8.3 1.8e-05 24.6 8.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKA03368.1 - 0.0048 17.1 0.7 0.0048 17.1 0.7 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain Laminin_II PF06009.12 KKA03368.1 - 0.0092 16.0 1.4 0.016 15.2 1.4 1.4 1 0 0 1 1 1 1 Laminin Domain II Spore_Cse60 PF10957.8 KKA03368.1 - 0.0093 16.0 1.4 2.3 8.3 0.1 2.8 2 0 0 2 2 2 1 Sporulation protein Cse60 NPV_P10 PF05531.12 KKA03368.1 - 0.033 14.7 0.7 0.27 11.7 0.6 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-HC5HC2H_2 PF13832.6 KKA03368.1 - 0.033 14.4 0.7 0.087 13.0 0.7 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain HCMV_UL139 PF12507.8 KKA03368.1 - 0.04 14.3 1.2 0.084 13.2 1.2 1.8 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF1464 PF07318.12 KKA03368.1 - 0.053 12.7 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) ABC_tran_CTD PF16326.5 KKA03368.1 - 0.061 13.6 8.2 0.14 12.4 1.0 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Uds1 PF15456.6 KKA03368.1 - 0.76 9.9 4.5 0.19 11.9 0.9 1.7 2 0 0 2 2 2 0 Up-regulated During Septation Fcf1 PF04900.12 KKA03369.1 - 3.4e-34 117.2 0.8 3.4e-34 117.2 0.8 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KKA03369.1 - 3.4e-13 49.9 0.0 6.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Tli4_N PF18443.1 KKA03369.1 - 0.045 14.1 0.3 0.071 13.5 0.3 1.3 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Apolipoprotein PF01442.18 KKA03370.1 - 0.0085 16.0 5.0 0.69 9.8 0.1 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Mei5 PF10376.9 KKA03370.1 - 0.017 15.0 13.8 0.097 12.5 13.8 1.8 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF3584 PF12128.8 KKA03370.1 - 0.048 11.2 11.2 0.059 10.9 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T3SSipB PF16535.5 KKA03370.1 - 0.064 13.7 2.2 0.083 13.4 0.8 1.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB Syntaxin-6_N PF09177.11 KKA03370.1 - 0.064 13.8 7.8 2 9.0 5.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 KKA03370.1 - 0.2 11.2 12.3 0.68 9.5 6.3 2.3 1 1 1 2 2 2 0 fzo-like conserved region YtxH PF12732.7 KKA03370.1 - 0.38 11.3 6.1 0.72 10.4 1.2 2.6 2 1 0 2 2 2 0 YtxH-like protein CHDCT2 PF08074.11 KKA03370.1 - 0.45 10.7 8.2 0.59 10.3 8.2 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DEAD PF00270.29 KKA03370.1 - 0.57 9.9 3.0 0.86 9.3 3.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Exonuc_VII_L PF02601.15 KKA03370.1 - 1.2 8.7 8.8 1.9 8.0 8.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 KKA03370.1 - 1.3 9.4 16.2 4.3 7.7 16.2 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ALMT PF11744.8 KKA03370.1 - 1.9 7.2 8.9 2.4 6.9 8.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF16 PF01519.16 KKA03370.1 - 3.4 8.2 18.0 5.3e+02 1.1 18.0 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Noelin-1 PF12308.8 KKA03370.1 - 3.8 7.5 6.5 1.3 9.0 2.1 2.2 1 1 2 3 3 3 0 Neurogenesis glycoprotein PNPase PF03726.14 KKA03370.1 - 5.3 7.6 7.7 4.5 7.8 2.2 2.8 1 1 2 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF1664 PF07889.12 KKA03370.1 - 7 6.7 11.4 6.1 6.9 1.4 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Mito_carr PF00153.27 KKA03371.1 - 2.6e-05 24.1 0.5 0.36 10.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2b PF00587.25 KKA03372.1 - 4.9e-24 85.3 0.0 7.9e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FliJ PF02050.16 KKA03372.1 - 0.051 13.8 4.1 0.12 12.6 4.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Ntox28 PF15605.6 KKA03372.1 - 0.13 12.5 1.0 0.36 11.1 1.0 1.8 1 0 0 1 1 1 0 Bacterial toxin 28 Seryl_tRNA_N PF02403.22 KKA03372.1 - 0.32 11.2 10.2 0.042 14.1 5.9 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SKA2 PF16740.5 KKA03372.1 - 1.5 8.6 9.1 0.36 10.6 3.3 2.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Acetyltransf_1 PF00583.25 KKA03373.1 - 2.1e-11 44.1 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKA03373.1 - 4.5e-06 26.6 0.2 6.7e-06 26.1 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKA03373.1 - 4.5e-05 23.3 0.0 7.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKA03373.1 - 0.0014 19.0 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKA03373.1 - 0.004 17.2 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKA03373.1 - 0.012 15.0 2.3 0.016 14.7 1.3 1.8 1 1 1 2 2 2 0 Putative acetyl-transferase TRAPP PF04051.16 KKA03374.1 - 1.2e-22 80.2 0.1 1.7e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2345 PF10106.9 KKA03375.1 - 0.062 13.2 0.2 0.096 12.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) SpuA_C PF18033.1 KKA03376.1 - 0.079 13.0 0.1 2.7 8.1 0.1 2.7 2 0 0 2 2 2 0 SpuA C-terminal BHD_3 PF10405.9 KKA03377.1 - 8e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KKA03377.1 - 0.00014 21.5 0.0 0.00058 19.6 0.0 2.0 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain FYVE PF01363.21 KKA03378.1 - 6.4e-16 58.2 7.2 6.4e-16 58.2 7.2 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KKA03378.1 - 2.5e-06 27.7 2.8 2.5e-06 27.7 2.8 4.0 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KKA03378.1 - 6.9e-05 22.8 0.9 6.9e-05 22.8 0.9 3.6 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_11 PF17123.5 KKA03378.1 - 0.0026 17.4 4.9 0.0026 17.4 4.9 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKA03378.1 - 0.012 15.4 2.9 0.012 15.4 2.9 3.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKA03378.1 - 0.014 15.2 2.7 0.014 15.2 2.7 4.3 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KKA03378.1 - 0.21 11.7 20.8 0.2 11.8 5.7 3.2 3 2 0 3 3 3 0 KIAA1045 RING finger FYVE_2 PF02318.16 KKA03378.1 - 6.6 7.0 24.1 0.19 11.9 8.8 2.8 1 1 2 3 3 3 0 FYVE-type zinc finger Brix PF04427.18 KKA03379.1 - 4e-41 141.2 4.5 4e-41 141.2 4.5 2.1 2 0 0 2 2 2 1 Brix domain DUF572 PF04502.13 KKA03379.1 - 0.94 9.0 34.8 1.5 8.4 34.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Paf1 PF03985.13 KKA03379.1 - 3 6.8 43.8 1.5 7.8 14.5 2.1 2 0 0 2 2 2 0 Paf1 DEAD PF00270.29 KKA03380.1 - 6.7e-48 162.8 0.0 1.7e-47 161.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA03380.1 - 2.8e-32 111.3 0.1 4.7e-31 107.4 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKA03380.1 - 3e-07 30.6 0.0 3e-07 30.6 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKA03380.1 - 0.014 14.6 0.1 0.014 14.6 0.1 2.3 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase TRAP_alpha PF03896.16 KKA03380.1 - 0.26 10.4 5.9 0.022 14.0 1.1 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit MecA PF05389.12 KKA03380.1 - 0.49 10.0 14.2 0.032 13.9 8.4 1.9 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Secretin_N_2 PF07655.13 KKA03380.1 - 9.1 6.9 8.9 0.61 10.7 2.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain WD40 PF00400.32 KKA03381.1 - 4.4e-30 103.3 14.2 0.0001 23.0 0.1 10.8 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03381.1 - 0.00049 20.3 6.0 4 7.8 0.0 6.5 6 2 1 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KKA03381.1 - 0.00088 19.3 5.3 0.38 10.8 0.1 5.3 5 1 1 6 6 6 3 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.6 KKA03381.1 - 0.027 13.8 0.1 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ToxS PF17323.2 KKA03381.1 - 0.11 12.1 4.3 0.35 10.5 0.2 3.1 3 0 0 3 3 3 0 Trans-membrane regulatory protein ToxS Agglutinin_C PF18021.1 KKA03381.1 - 0.13 12.7 0.3 0.4 11.2 0.1 1.9 2 0 0 2 2 2 0 Agglutinin C-terminal PMT PF02366.18 KKA03382.1 - 3.1e-49 167.8 15.4 3.1e-49 167.8 15.4 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKA03382.1 - 7.5e-40 136.7 7.9 7.5e-40 136.7 7.9 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKA03382.1 - 2.4e-13 50.3 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KKA03382.1 - 6.3e-06 26.5 13.9 6.3e-06 26.5 13.9 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ThiJ_like PF17124.5 KKA03382.1 - 0.0059 16.3 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 ThiJ/PfpI family-like FTHFS PF01268.19 KKA03383.1 - 3e-238 791.5 0.6 4.2e-238 791.1 0.6 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KKA03383.1 - 6.9e-46 155.5 0.5 1.7e-44 151.0 0.1 3.0 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KKA03383.1 - 6.6e-33 113.4 4.9 1.7e-32 112.1 4.9 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain VanW PF04294.13 KKA03383.1 - 0.06 13.0 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 VanW like protein Ins_P5_2-kin PF06090.12 KKA03384.1 - 2.2e-10 40.5 3.5 4.5e-09 36.2 0.0 2.3 1 1 0 2 2 2 2 Inositol-pentakisphosphate 2-kinase MaoC_dehydratas PF01575.19 KKA03385.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 MaoC like domain PX PF00787.24 KKA03386.1 - 1.4e-09 37.9 3.4 1.4e-09 37.9 3.4 2.8 2 2 0 2 2 2 1 PX domain DUF4335 PF14233.6 KKA03386.1 - 0.26 11.2 2.6 0.48 10.3 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF3461 PF11944.8 KKA03386.1 - 8 6.6 24.0 0.021 15.0 6.6 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3461) DS PF01916.17 KKA03387.1 - 4.2e-126 420.1 0.0 4.9e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase YjcQ PF09639.10 KKA03387.1 - 0.0096 16.1 0.6 0.022 15.0 0.6 1.6 1 0 0 1 1 1 1 YjcQ protein dCMP_cyt_deam_1 PF00383.23 KKA03388.1 - 2.7e-11 43.2 0.0 4.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKA03388.1 - 9.1e-11 41.7 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KKA03388.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 KKA03388.1 - 0.018 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Methyltransf_23 PF13489.6 KKA03389.1 - 5.4e-20 71.9 0.1 3.4e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA03389.1 - 2.5e-11 44.1 0.1 1.3e-10 41.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKA03389.1 - 6.8e-11 42.7 0.0 1.8e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA03389.1 - 5.7e-10 39.8 0.1 2.7e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKA03389.1 - 1.1e-08 34.7 0.1 2.7e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KKA03389.1 - 9.6e-07 28.7 1.3 1.4e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 KKA03389.1 - 0.017 14.7 0.1 0.046 13.3 0.1 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Comm PF15957.5 KKA03389.1 - 0.04 14.3 0.1 0.093 13.1 0.1 1.6 1 0 0 1 1 1 0 Commissureless KH_6 PF15985.5 KKA03390.1 - 2.7e-06 27.6 0.2 5.9e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KKA03390.1 - 4.3e-06 26.4 0.0 9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ribosomal_L14 PF00238.19 KKA03390.1 - 0.027 14.5 0.6 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e Met_10 PF02475.16 KKA03391.1 - 2.5e-56 190.6 1.2 2.1e-44 151.6 0.6 2.3 2 0 0 2 2 2 2 Met-10+ like-protein TRM PF02005.16 KKA03391.1 - 0.0067 15.6 0.1 0.0067 15.6 0.1 1.6 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase CCDC158 PF15921.5 KKA03391.1 - 0.049 11.5 0.2 0.094 10.5 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 NOC3p PF07540.11 KKA03393.1 - 2.8e-23 82.2 0.8 2.8e-23 82.2 0.8 2.8 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 KKA03393.1 - 3.3e-11 43.5 2.9 3.5e-11 43.4 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Mpp10 PF04006.12 KKA03394.1 - 3.4e-106 356.1 89.4 4.1e-106 355.8 89.4 1.0 1 0 0 1 1 1 1 Mpp10 protein Aa_trans PF01490.18 KKA03395.1 - 9.6e-71 238.6 19.8 1.1e-70 238.4 19.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Alg14 PF08660.11 KKA03395.1 - 0.029 14.3 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like HNF_C PF09354.10 KKA03395.1 - 0.049 14.7 1.5 0.74 10.9 1.5 2.6 1 1 0 1 1 1 0 HNF3 C-terminal domain CRA PF06589.11 KKA03395.1 - 0.097 12.8 1.6 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Fasciclin PF02469.22 KKA03396.1 - 1.1e-15 58.0 2.6 2.1e-08 34.4 0.0 5.0 5 1 0 5 5 5 4 Fasciclin domain UPF0086 PF01868.16 KKA03397.1 - 4.3e-20 71.4 0.1 6.3e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Rad60-SLD_2 PF13881.6 KKA03397.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like COMPASS-Shg1 PF05205.12 KKA03398.1 - 9e-11 42.4 4.7 1.2e-10 42.0 4.7 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4080 PF13311.6 KKA03398.1 - 0.0066 16.7 1.0 0.013 15.7 0.9 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4080) RNase_J_C PF17770.1 KKA03398.1 - 0.073 14.1 6.6 0.14 13.3 1.8 2.6 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain COQ7 PF03232.13 KKA03398.1 - 0.13 12.1 1.5 0.21 11.3 1.5 1.6 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 HAT_KAT11 PF08214.11 KKA03399.1 - 3.7e-83 279.7 3.1 4.5e-83 279.4 3.1 1.0 1 0 0 1 1 1 1 Histone acetylation protein Sfi1 PF08457.10 KKA03400.1 - 5.8e-09 35.0 16.7 5.8e-09 35.0 16.7 3.0 1 1 1 3 3 3 3 Sfi1 spindle body protein Proteasome PF00227.26 KKA03401.1 - 1.5e-49 168.1 0.6 1.7e-49 167.9 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit Dynamin_M PF01031.20 KKA03402.1 - 6.9e-101 337.2 2.3 6.9e-101 337.2 2.3 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KKA03402.1 - 2.9e-53 180.4 0.1 2.9e-53 180.4 0.1 3.1 3 1 1 4 4 4 1 Dynamin family GED PF02212.18 KKA03402.1 - 3.5e-26 91.2 2.5 1.2e-25 89.4 2.5 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKA03402.1 - 1.1e-05 25.4 1.5 0.012 15.7 0.0 3.7 4 0 0 4 4 4 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KKA03402.1 - 0.013 15.3 3.5 0.014 15.2 0.3 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system GerPC PF10737.9 KKA03402.1 - 0.031 14.3 9.9 0.036 14.1 1.8 3.0 3 0 0 3 3 3 0 Spore germination protein GerPC ZnuA PF01297.17 KKA03402.1 - 0.04 13.3 0.1 0.089 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic ABC_tran PF00005.27 KKA03402.1 - 0.062 13.8 1.1 0.7 10.4 0.0 2.9 3 0 0 3 3 3 0 ABC transporter Mga PF05043.13 KKA03403.1 - 0.043 14.4 0.9 0.14 12.8 0.9 1.8 1 0 0 1 1 1 0 Mga helix-turn-helix domain Vasculin PF15337.6 KKA03404.1 - 0.073 13.9 1.8 0.13 13.1 0.1 2.3 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 DUF4325 PF14213.6 KKA03404.1 - 0.65 9.7 5.8 19 5.0 0.2 3.5 3 0 0 3 3 3 0 STAS-like domain of unknown function (DUF4325) Ribophorin_I PF04597.14 KKA03405.1 - 4.2e-51 174.5 11.4 8e-51 173.6 11.3 1.4 1 1 0 1 1 1 1 Ribophorin I ILVD_EDD PF00920.21 KKA03406.1 - 3.2e-205 682.7 0.3 3.6e-205 682.5 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family COX16 PF14138.6 KKA03407.1 - 1.3e-23 83.3 0.1 2.1e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 ADH_zinc_N PF00107.26 KKA03408.1 - 4.2e-05 23.5 0.0 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKA03408.1 - 0.00014 21.7 0.5 0.00053 19.9 0.4 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pro_isomerase PF00160.21 KKA03409.1 - 2.6e-36 125.3 0.1 3e-36 125.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans PF04082.18 KKA03410.1 - 3.5e-18 65.6 1.3 3.5e-18 65.6 1.3 3.3 1 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA03410.1 - 3.5e-06 27.0 11.5 7.4e-06 26.0 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.18 KKA03411.1 - 6.6e-25 88.4 0.6 1.1e-24 87.6 0.6 1.4 1 0 0 1 1 1 1 Brix domain Cwf_Cwc_15 PF04889.12 KKA03411.1 - 2.9 7.6 20.2 0.26 11.0 15.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BPL_N PF09825.9 KKA03411.1 - 7.6 5.5 6.6 11 5.0 6.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Xpo1 PF08389.12 KKA03412.1 - 0.012 15.7 0.4 0.012 15.7 0.4 4.1 4 0 0 4 4 4 0 Exportin 1-like protein PPL4 PF18188.1 KKA03412.1 - 0.046 13.7 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Prim-pol 4 Gar1 PF04410.14 KKA03413.1 - 2.8e-30 105.1 0.0 3.6e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribosomal_S15 PF00312.22 KKA03414.1 - 5.2e-13 49.0 0.1 1.2e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 Abhydrolase_6 PF12697.7 KKA03415.1 - 2.8e-12 47.7 0.0 4.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKA03415.1 - 1.2e-11 44.8 0.1 1.8e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA03415.1 - 4.6e-08 32.6 0.0 8.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KKA03415.1 - 6e-05 22.7 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KKA03415.1 - 0.00096 18.9 0.1 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.25 KKA03415.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KKA03415.1 - 0.026 14.0 0.3 0.066 12.7 0.3 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) CN_hydrolase PF00795.22 KKA03416.1 - 3.3e-33 115.1 0.0 4.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KKA03416.1 - 9.6e-23 80.6 0.0 2.7e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 NAD synthase TFA2_Winged_2 PF18121.1 KKA03417.1 - 7.4e-20 70.4 0.2 7.4e-20 70.4 0.2 2.0 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 Med6 PF04934.14 KKA03418.1 - 4.1e-34 117.2 2.5 6.9e-34 116.5 2.5 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.10 KKA03419.1 - 1e-17 64.0 0.5 5.7e-17 61.6 0.1 2.2 2 0 0 2 2 2 1 IGR protein motif zf-C4H2 PF10146.9 KKA03419.1 - 0.09 13.1 0.8 0.16 12.2 0.8 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein LRR_4 PF12799.7 KKA03420.1 - 0.078 13.4 18.0 1.7 9.2 1.5 5.8 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KKA03420.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 KKA03420.1 - 0.33 10.8 4.2 20 5.1 0.1 4.0 3 1 1 4 4 4 0 Leucine rich repeat RVT_2 PF07727.14 KKA03421.1 - 2.8e-26 92.7 0.0 5.1e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KKA03421.1 - 3.8e-09 36.8 0.0 9.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Med21 PF11221.8 KKA03422.1 - 1.1e-23 84.1 16.7 5.5e-22 78.6 16.7 2.1 1 1 0 1 1 1 1 Subunit 21 of Mediator complex tRNA-synt_2e PF02091.15 KKA03422.1 - 0.099 11.9 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit MIR PF02815.19 KKA03423.1 - 4.7e-11 42.9 0.1 8e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 MIR domain RNase_P_p30 PF01876.16 KKA03424.1 - 4.2e-41 140.8 3.9 8.3e-41 139.8 3.1 1.9 2 1 0 2 2 2 1 RNase P subunit p30 DUF262 PF03235.14 KKA03424.1 - 0.12 12.5 5.1 0.047 13.9 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 Ssl1 PF04056.14 KKA03425.1 - 6.9e-66 221.7 0.1 1e-65 221.2 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KKA03425.1 - 1.3e-17 63.7 8.5 1.3e-17 63.7 8.5 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KKA03425.1 - 1.2e-14 54.9 0.0 3.5e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKA03425.1 - 1.2e-09 38.7 0.0 2.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 KKA03425.1 - 0.019 14.9 6.2 0.019 14.9 6.2 3.2 2 1 0 2 2 2 0 Double zinc ribbon Tfb4 PF03850.14 KKA03425.1 - 1.1 8.7 0.0 1.1 8.7 0.0 3.1 3 0 0 3 3 3 0 Transcription factor Tfb4 zf-B_box PF00643.24 KKA03425.1 - 6.7 6.9 24.3 0.064 13.4 7.0 3.2 2 1 0 2 2 2 0 B-box zinc finger RR_TM4-6 PF06459.12 KKA03425.1 - 8 6.2 13.5 13 5.5 13.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GnHR_trans PF12369.8 KKA03426.1 - 0.039 14.8 0.1 0.12 13.2 0.1 1.8 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region HSP70 PF00012.20 KKA03427.1 - 1.3e-55 188.8 5.8 1.7e-55 188.4 5.8 1.2 1 0 0 1 1 1 1 Hsp70 protein ApbA PF02558.16 KKA03428.1 - 2.6e-26 92.1 0.0 4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KKA03428.1 - 3.6e-24 85.3 0.0 5.6e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.23 KKA03428.1 - 0.011 15.7 0.4 0.071 13.1 0.0 2.1 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KKA03428.1 - 0.019 15.5 0.0 0.043 14.4 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KKA03428.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1296 PF06972.11 KKA03428.1 - 0.32 11.2 2.9 0.35 11.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) PIG-F PF06699.11 KKA03430.1 - 1.8e-17 64.1 15.9 1.5e-16 61.1 15.9 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2070 PF09843.9 KKA03430.1 - 1.2 7.4 10.2 1.4 7.1 10.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM24 PF01987.17 KKA03431.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.18 KKA03432.1 - 0.0066 16.5 12.1 0.011 15.8 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L24e PF01246.20 KKA03433.1 - 3.2e-31 107.4 5.3 3.2e-31 107.4 5.3 2.4 2 0 0 2 2 2 1 Ribosomal protein L24e Ribosomal_L35Ae PF01247.18 KKA03433.1 - 0.16 12.2 1.4 5.9 7.1 0.2 2.6 1 1 1 2 2 2 0 Ribosomal protein L35Ae Pam16 PF03656.13 KKA03434.1 - 0.00021 21.3 0.1 0.0003 20.8 0.1 1.3 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KKA03434.1 - 0.0032 17.6 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain SMC_Nse1 PF07574.13 KKA03435.1 - 0.011 15.6 3.1 0.35 10.7 3.0 2.4 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DUF4430 PF14478.6 KKA03435.1 - 0.21 12.2 0.8 4.4 8.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4430) FYVE PF01363.21 KKA03435.1 - 2.7 8.2 6.8 5.3 7.3 6.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger MatE PF01554.18 KKA03436.1 - 2.4e-29 102.1 35.1 2.8e-17 62.9 12.9 3.3 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KKA03436.1 - 4.4e-07 30.1 3.3 4.4e-07 30.1 3.3 5.1 5 2 1 6 6 6 2 Polysaccharide biosynthesis C-terminal domain TRAUB PF08164.12 KKA03437.1 - 7e-16 58.5 1.3 7e-16 58.5 1.3 4.0 4 2 1 5 5 5 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KKA03437.1 - 5.8e-09 36.8 9.1 5.8e-09 36.8 9.1 4.0 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor PIH1 PF08190.12 KKA03438.1 - 1e-08 34.8 0.4 1.8e-08 34.0 0.4 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain EF_TS PF00889.19 KKA03438.1 - 0.022 14.4 1.8 0.031 13.9 1.8 1.2 1 0 0 1 1 1 0 Elongation factor TS RNase_J_C PF17770.1 KKA03438.1 - 0.14 13.2 1.1 2.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain AA_kinase PF00696.28 KKA03439.1 - 1.2e-36 126.5 0.4 1.9e-36 125.9 0.4 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KKA03439.1 - 5.7e-20 71.1 0.1 1.6e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 KKA03439.1 - 0.14 12.0 0.2 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 PUA-like domain CPSF_A PF03178.15 KKA03441.1 - 7.6e-15 55.0 0.1 5.4e-08 32.5 0.2 3.2 2 1 1 3 3 3 3 CPSF A subunit region MFS_1 PF07690.16 KKA03442.1 - 7.8e-31 107.3 21.8 7.8e-31 107.3 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KKA03443.1 - 6.8e-32 110.8 18.0 6.8e-32 110.8 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_92 PF07971.12 KKA03444.1 - 1e-95 321.4 0.1 2.2e-95 320.3 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKA03444.1 - 5.3e-43 147.6 0.7 8.1e-43 147.0 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GBP_C PF02841.14 KKA03445.1 - 0.24 10.8 8.0 0.023 14.1 2.3 1.9 1 1 0 2 2 2 0 Guanylate-binding protein, C-terminal domain tRNA_int_endo PF01974.17 KKA03447.1 - 2.9e-10 40.1 0.6 6.9e-10 38.9 0.0 1.9 3 0 0 3 3 3 1 tRNA intron endonuclease, catalytic C-terminal domain nsp9 PF08710.10 KKA03447.1 - 0.014 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 nsp9 replicase BRCT_2 PF16589.5 KKA03447.1 - 0.017 15.6 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Pkinase PF00069.25 KKA03448.1 - 9.5e-64 215.3 13.3 3.2e-42 144.7 3.4 4.2 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KKA03448.1 - 3e-44 151.5 16.2 8.2e-24 84.5 0.2 3.1 2 1 1 3 3 3 2 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KKA03448.1 - 1.8e-35 122.5 5.1 2.8e-22 79.3 0.5 4.4 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KKA03448.1 - 1.1e-13 51.2 0.0 2.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 KKA03448.1 - 2.4e-12 47.2 5.4 2.4e-12 47.2 5.4 2.8 2 0 0 2 2 2 1 RWD domain Kdo PF06293.14 KKA03448.1 - 0.0018 17.7 0.2 0.64 9.3 0.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family TMV_coat PF00721.21 KKA03448.1 - 0.017 15.0 0.4 0.073 12.9 0.4 2.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) DUF1194 PF06707.11 KKA03448.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) PAP2 PF01569.21 KKA03449.1 - 1.5e-26 92.8 0.0 3.5e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KKA03449.1 - 0.0042 16.8 4.0 0.93 9.2 0.7 2.6 2 2 0 2 2 2 2 PAP2 superfamily 7TM_GPCR_Sri PF10327.9 KKA03449.1 - 0.064 12.4 3.4 0.12 11.6 3.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri DUF4293 PF14126.6 KKA03449.1 - 0.065 13.5 0.7 0.12 12.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) AA_permease_2 PF13520.6 KKA03449.1 - 0.84 8.4 6.9 1.6 7.5 6.8 1.5 1 1 0 1 1 1 0 Amino acid permease NPCC PF08058.11 KKA03449.1 - 1.2 9.2 3.0 0.73 9.9 0.2 2.0 2 0 0 2 2 2 0 Nuclear pore complex component Asparaginase PF00710.20 KKA03450.1 - 3.9e-54 183.1 0.0 1.1e-53 181.7 0.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KKA03450.1 - 1e-19 70.8 0.0 1.8e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain HTS PF04204.16 KKA03450.1 - 0.12 11.3 0.1 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Homoserine O-succinyltransferase Transp_cyt_pur PF02133.15 KKA03451.1 - 3.2e-27 95.4 39.0 7.4e-27 94.2 39.0 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin T_cell_tran_alt PF15128.6 KKA03451.1 - 0.15 11.9 0.6 12 5.8 0.1 2.9 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DIOX_N PF14226.6 KKA03452.1 - 5.6e-19 69.0 0.5 2.8e-18 66.8 0.1 2.1 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKA03452.1 - 2.1e-17 63.4 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3150 PF11348.8 KKA03452.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Protamine_like PF06382.11 KKA03454.1 - 0.088 13.0 1.7 0.28 11.4 0.7 2.1 2 0 0 2 2 2 0 Protamine and protamine like zf-Sec23_Sec24 PF04810.15 KKA03454.1 - 0.16 12.0 4.3 0.09 12.8 1.6 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-FPG_IleRS PF06827.14 KKA03454.1 - 0.16 11.8 1.4 0.51 10.3 1.4 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS RecR PF02132.15 KKA03454.1 - 0.22 11.1 2.3 0.49 10.0 2.3 1.6 1 0 0 1 1 1 0 RecR protein Mhr1 PF12829.7 KKA03455.1 - 5.4e-10 39.2 0.1 9.7e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FA_hydroxylase PF04116.13 KKA03456.1 - 3.2e-23 82.5 6.6 3.2e-23 82.5 6.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 2TM PF13239.6 KKA03456.1 - 0.13 12.6 0.0 0.13 12.6 0.0 3.2 3 0 0 3 3 3 0 2TM domain OSCP PF00213.18 KKA03457.1 - 5.2e-37 127.6 1.5 6.2e-37 127.4 1.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DEAD PF00270.29 KKA03458.1 - 2.7e-20 72.9 0.4 2.6e-19 69.6 0.0 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KKA03458.1 - 2.3e-16 60.3 0.6 2.3e-16 60.3 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KKA03458.1 - 1.5e-14 54.3 0.3 5.9e-11 42.7 0.1 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKA03458.1 - 1.3e-08 35.1 0.2 1.3e-08 35.1 0.2 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAD_binding_1 PF00667.20 KKA03460.1 - 9.5e-58 195.4 0.0 1.6e-57 194.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KKA03460.1 - 3e-22 79.4 0.8 5.4e-22 78.6 0.1 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KKA03460.1 - 3.5e-20 72.7 0.0 1.6e-19 70.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KKA03460.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Flavodoxin domain MAGE PF01454.19 KKA03461.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 MAGE family Bromo_TP_like PF17027.5 KKA03461.1 - 0.024 14.8 0.9 0.096 12.8 0.3 2.2 2 0 0 2 2 2 0 Histone-fold protein Gp_dh_C PF02800.20 KKA03462.1 - 4.1e-72 240.9 0.1 9e-72 239.8 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KKA03462.1 - 1.5e-36 124.8 0.0 3.2e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KKA03462.1 - 0.013 15.7 0.1 0.042 14.0 0.1 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RSN1_7TM PF02714.15 KKA03463.1 - 5.3e-59 199.8 34.0 5.3e-59 199.8 34.0 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKA03463.1 - 4e-15 55.9 5.2 1.4e-14 54.1 3.8 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KKA03463.1 - 0.00063 19.9 0.0 0.0027 17.9 0.0 2.2 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF969 PF06149.12 KKA03463.1 - 0.11 11.9 3.2 0.065 12.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF969) MMM1 PF10296.9 KKA03464.1 - 6.5e-115 383.7 0.7 9e-115 383.2 0.7 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DEAD PF00270.29 KKA03465.1 - 3e-46 157.4 0.2 8.1e-46 156.0 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA03465.1 - 1.6e-29 102.5 0.1 1.6e-29 102.5 0.1 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKA03465.1 - 0.14 12.4 1.3 0.35 11.2 0.4 2.3 2 1 0 2 2 2 0 AAA domain DUF3964 PF13107.6 KKA03465.1 - 1 9.8 7.5 0.21 12.0 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3964) CTP_transf_like PF01467.26 KKA03466.1 - 4.5e-34 117.7 0.0 1.4e-33 116.1 0.0 1.9 1 0 0 1 1 1 1 Cytidylyltransferase-like Cwf_Cwc_15 PF04889.12 KKA03466.1 - 1.3 8.7 34.1 0.7 9.6 19.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rhodanese PF00581.20 KKA03467.1 - 1e-08 35.6 0.1 1.4e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF1958 PF09211.10 KKA03467.1 - 0.03 14.6 0.1 0.052 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) DUF3892 PF13031.6 KKA03467.1 - 0.061 14.0 0.8 1.1 10.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3892) FSH1 PF03959.13 KKA03468.1 - 6.3e-59 199.2 0.0 7e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKA03468.1 - 0.013 15.3 0.4 0.57 10.0 0.4 2.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Nramp PF01566.18 KKA03469.1 - 8e-77 258.6 15.2 3.4e-42 144.7 6.2 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Calcipressin PF04847.12 KKA03470.1 - 1.4e-09 38.0 0.1 1.8e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Calcipressin COX5A PF02284.16 KKA03471.1 - 1.6e-36 124.4 0.7 2.1e-36 124.0 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF3523 PF12037.8 KKA03471.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) SpoIIP PF07454.11 KKA03471.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Elf1 PF05129.13 KKA03472.1 - 4.9e-24 84.2 3.5 7.2e-24 83.6 3.5 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.19 KKA03472.1 - 0.0064 16.5 0.5 0.013 15.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L37ae protein family Lar_restr_allev PF14354.6 KKA03472.1 - 0.016 15.6 0.4 0.032 14.6 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar SURF2 PF05477.11 KKA03472.1 - 2.4 7.8 8.9 3.3 7.3 8.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) EIF_2_alpha PF07541.12 KKA03473.1 - 1.8e-34 118.3 0.4 4.1e-34 117.2 0.4 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KKA03473.1 - 5.5e-15 55.5 1.3 1.3e-14 54.3 1.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain IRF-2BP1_2 PF11261.8 KKA03473.1 - 0.066 12.8 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Baculo_gp41 PF04700.12 KKA03473.1 - 0.44 10.3 3.5 3.5 7.3 0.5 2.8 2 1 1 3 3 3 0 Structural glycoprotein p40/gp41 conserved region Memo PF01875.17 KKA03474.1 - 2.2e-47 161.5 0.4 3.3e-47 160.9 0.4 1.3 1 1 0 1 1 1 1 Memo-like protein PUF PF00806.19 KKA03475.1 - 2.4e-22 77.3 17.3 5.5e-05 22.6 0.0 8.4 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Arm-DNA-bind_5 PF17293.2 KKA03475.1 - 0.023 15.1 4.2 0.54 10.7 0.0 3.9 3 0 0 3 3 3 0 Arm DNA-binding domain DUF3294 PF07957.11 KKA03476.1 - 1.2e-49 169.0 12.3 1.3e-49 168.8 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) TBK1_ULD PF18396.1 KKA03476.1 - 0.092 12.7 0.6 0.32 10.9 0.6 1.9 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain GBP_C PF02841.14 KKA03476.1 - 1.1 8.6 7.6 7.7 5.8 3.3 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain LTV PF04180.14 KKA03477.1 - 4.5e-82 276.8 32.9 9.3e-82 275.8 32.9 1.5 1 1 0 1 1 1 1 Low temperature viability protein RNA_pol_Rbc25 PF08292.12 KKA03478.1 - 3.9e-38 130.6 3.2 4.7e-34 117.4 0.7 2.2 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KKA03478.1 - 4.1e-14 52.7 0.0 8.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AAA PF00004.29 KKA03479.1 - 3.5e-40 137.5 0.0 7.6e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA03479.1 - 1.6e-06 27.8 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KKA03479.1 - 4.3e-05 23.8 0.0 0.002 18.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKA03479.1 - 7.7e-05 22.7 0.0 0.00032 20.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKA03479.1 - 0.00012 22.5 0.1 0.0055 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KKA03479.1 - 0.00031 20.9 0.0 0.00064 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKA03479.1 - 0.00038 19.7 0.0 0.00083 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KKA03479.1 - 0.0034 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KKA03479.1 - 0.0052 16.5 0.4 0.08 12.7 0.1 2.7 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KKA03479.1 - 0.015 15.2 0.3 5.6 6.8 0.0 3.0 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KKA03479.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKA03479.1 - 0.024 15.2 0.1 0.082 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKA03479.1 - 0.03 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKA03479.1 - 0.03 14.7 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 KKA03479.1 - 0.032 13.7 0.0 0.085 12.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KKA03479.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKA03479.1 - 0.056 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KKA03479.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KKA03479.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KKA03479.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain FAD_binding_2 PF00890.24 KKA03480.1 - 6.5e-121 404.3 4.0 8.3e-121 403.9 4.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KKA03480.1 - 2.1e-38 131.2 0.1 3.2e-38 130.6 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KKA03480.1 - 4.3e-05 22.9 1.9 0.001 18.4 0.9 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKA03480.1 - 0.00011 21.4 0.9 0.0021 17.2 0.4 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KKA03480.1 - 0.00051 19.3 0.6 0.093 12.0 0.1 2.7 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 KKA03480.1 - 0.015 14.6 0.3 0.015 14.6 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Protoglobin PF11563.8 KKA03480.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Protoglobin HI0933_like PF03486.14 KKA03480.1 - 0.11 11.1 3.5 0.091 11.4 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 KKA03480.1 - 0.24 10.9 5.2 1.6 8.2 5.2 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKA03480.1 - 0.36 10.0 1.5 1.1 8.4 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 KKA03481.1 - 2.4e-07 31.5 0.4 4e-07 30.7 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_1 PF00175.21 KKA03482.1 - 9.5e-26 90.6 0.0 1.6e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKA03482.1 - 2.8e-22 78.9 0.0 5.5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKA03482.1 - 2e-09 37.7 0.3 2.2e-07 31.2 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Carb_kinase PF01256.17 KKA03483.1 - 1.5e-25 90.1 0.0 3.7e-24 85.5 0.0 2.5 1 1 0 1 1 1 1 Carbohydrate kinase His_Phos_1 PF00300.22 KKA03484.1 - 8.6e-35 120.2 0.0 4.7e-27 94.9 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Nucleoporin_FG PF13634.6 KKA03486.1 - 0.00098 19.9 38.7 0.0033 18.2 15.1 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Nsp1_C PF05064.13 KKA03487.1 - 0.0011 18.8 3.7 0.0014 18.4 0.1 2.4 2 1 1 3 3 3 1 Nsp1-like C-terminal region DUF445 PF04286.12 KKA03487.1 - 0.017 15.0 5.3 0.019 14.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF5402 PF17393.2 KKA03487.1 - 0.089 12.7 0.2 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5402) Fib_alpha PF08702.10 KKA03487.1 - 3.2 7.9 10.6 0.94 9.7 5.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Muted PF14942.6 KKA03487.1 - 6 7.2 8.0 1.5 9.1 0.3 2.7 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Nup192 PF11894.8 KKA03488.1 - 1.5e-235 784.9 116.4 1.3e-234 781.8 116.4 1.9 1 1 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Pox_Ag35 PF03286.14 KKA03488.1 - 0.044 13.6 0.4 0.17 11.7 0.4 2.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FliD_N PF02465.18 KKA03488.1 - 2.8 8.7 6.3 2.3 9.0 2.1 3.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DPM2 PF07297.12 KKA03489.1 - 0.00047 20.4 5.6 0.0012 19.1 5.6 1.6 1 1 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MWFE PF15879.5 KKA03489.1 - 0.061 13.5 0.0 0.42 10.8 0.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2755 PF10954.8 KKA03489.1 - 0.73 9.8 4.4 2.7 8.0 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) S_tail_recep_bd PF14928.6 KKA03490.1 - 4.2 8.1 7.6 3.6 8.2 0.5 3.6 3 2 1 4 4 4 0 Short tail fibre protein receptor-binding domain Myosin_head PF00063.21 KKA03491.1 - 2.2e-227 756.6 31.5 2.2e-227 756.6 31.5 2.7 2 1 1 3 3 3 1 Myosin head (motor domain) AAA_22 PF13401.6 KKA03491.1 - 0.0091 16.3 7.8 0.027 14.7 0.0 4.7 5 1 0 5 5 5 1 AAA domain AAA_7 PF12775.7 KKA03491.1 - 0.028 13.9 2.1 0.46 10.0 0.1 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KKA03491.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KKA03491.1 - 0.049 14.0 2.0 0.78 10.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKA03491.1 - 0.073 13.4 0.0 0.44 10.9 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain Myosin_N PF02736.19 KKA03491.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain TPK_catalytic PF04263.16 KKA03491.1 - 2.2 8.4 8.0 3.5 7.7 0.5 3.5 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DivIC PF04977.15 KKA03492.1 - 0.0051 16.6 0.4 0.0051 16.6 0.4 8.7 3 3 6 10 10 10 3 Septum formation initiator YabA PF06156.13 KKA03492.1 - 0.012 16.3 4.4 0.012 16.3 4.4 6.7 1 1 5 6 6 6 0 Initiation control protein YabA ZapB PF06005.12 KKA03492.1 - 0.028 14.9 2.5 0.028 14.9 2.5 7.6 2 2 2 6 6 6 0 Cell division protein ZapB rve_3 PF13683.6 KKA03492.1 - 0.11 12.3 2.6 0.31 10.8 1.1 2.6 2 0 0 2 2 2 0 Integrase core domain CENP-F_leu_zip PF10473.9 KKA03492.1 - 1.6 8.7 82.2 0.02 14.9 20.3 5.8 2 2 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_M16_C PF05193.21 KKA03493.1 - 4.1e-32 111.7 0.0 9e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKA03493.1 - 1.3e-18 67.4 0.1 2.3e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Apocytochr_F_N PF16639.5 KKA03493.1 - 0.042 14.1 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Apocytochrome F, N-terminal GHMP_kinases_N PF00288.26 KKA03494.1 - 5.1e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKA03494.1 - 8.6e-05 22.8 0.0 0.00092 19.5 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal ATP-synt_C PF00137.21 KKA03495.1 - 6.3e-25 87.3 29.3 2.8e-15 56.4 11.8 2.3 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KKA03495.1 - 0.24 10.7 1.1 0.32 10.3 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RPN1_RPN2_N PF17781.1 KKA03496.1 - 1e-85 287.9 13.1 2e-85 286.9 13.1 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KKA03496.1 - 1.6e-28 98.5 0.1 3.6e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KKA03496.1 - 2.5e-13 49.7 19.1 5.4e-06 26.6 1.0 8.3 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KKA03496.1 - 4.7e-05 23.7 0.0 0.059 13.8 0.0 3.9 2 1 1 3 3 3 1 HEAT repeats Utp13 PF08625.11 KKA03496.1 - 0.0014 18.5 4.7 0.0017 18.2 1.1 3.0 4 0 0 4 4 4 1 Utp13 specific WD40 associated domain DUF3520 PF12034.8 KKA03496.1 - 0.025 14.7 1.3 0.16 12.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3520) S-antigen PF05756.11 KKA03496.1 - 5.7 7.4 14.7 2.3 8.6 3.7 2.8 2 0 0 2 2 2 0 S-antigen protein MAM33 PF02330.16 KKA03497.1 - 8.7e-36 123.9 7.7 8.7e-36 123.9 7.7 1.4 2 0 0 2 2 2 1 Mitochondrial glycoprotein MAM33 PF02330.16 KKA03498.1 - 2.6e-23 83.1 10.3 3.8e-23 82.6 10.3 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein PIF1 PF05970.14 KKA03499.1 - 3.9e-59 200.6 0.6 1.7e-56 192.0 0.6 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KKA03499.1 - 6e-22 78.3 0.0 2.3e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKA03499.1 - 3.1e-09 37.3 0.0 8e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKA03499.1 - 0.00081 18.9 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KKA03499.1 - 0.0022 17.8 3.1 0.11 12.3 0.3 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KKA03499.1 - 0.0026 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KKA03499.1 - 0.0034 17.6 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KKA03499.1 - 0.0057 17.0 1.4 0.057 13.8 0.0 3.0 2 0 0 2 2 2 1 RNA helicase DUF2075 PF09848.9 KKA03499.1 - 0.012 14.9 0.9 0.025 13.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KKA03499.1 - 0.018 14.9 1.4 0.062 13.1 0.1 2.5 2 1 0 2 2 2 0 Helicase AAA PF00004.29 KKA03499.1 - 0.02 15.3 0.8 0.071 13.5 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KKA03499.1 - 0.034 14.0 5.9 0.17 11.6 0.0 3.4 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KKA03499.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KKA03499.1 - 0.047 13.4 0.1 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 KKA03499.1 - 0.057 13.2 1.6 0.23 11.3 0.2 2.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Sigma54_activat PF00158.26 KKA03499.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KKA03499.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KKA03499.1 - 0.18 12.3 0.2 0.18 12.3 0.2 2.6 3 0 0 3 3 2 0 ABC transporter ATPase_2 PF01637.18 KKA03499.1 - 0.71 9.7 6.7 1.1 9.1 0.3 3.2 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KKA03499.1 - 4.9 7.2 8.0 11 6.1 0.2 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain Pkinase PF00069.25 KKA03500.1 - 9e-64 215.4 0.0 1.2e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03500.1 - 1.7e-31 109.5 0.0 2.4e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA03500.1 - 0.00013 21.1 0.4 0.00023 20.3 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKA03500.1 - 0.0055 16.1 0.1 0.0088 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Syntaxin_2 PF14523.6 KKA03500.1 - 0.0064 16.8 3.5 0.66 10.4 2.0 2.5 2 0 0 2 2 2 2 Syntaxin-like protein APH PF01636.23 KKA03500.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DPPIV_N PF00930.21 KKA03501.1 - 2.5e-96 322.5 8.3 3.6e-96 322.0 8.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KKA03501.1 - 2.3e-44 151.4 1.4 4e-44 150.6 1.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KKA03501.1 - 0.0019 18.1 0.4 3.2 7.5 0.0 2.8 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KKA03501.1 - 0.009 15.6 0.3 0.062 12.9 0.1 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KKA03501.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KKA03501.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KKA03501.1 - 0.026 14.1 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Sugar_tr PF00083.24 KKA03502.1 - 1.2e-107 360.6 34.0 1.5e-107 360.3 34.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA03502.1 - 4.6e-28 98.2 23.3 5.9e-24 84.6 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SHR3_chaperone PF08229.11 KKA03502.1 - 0.004 16.1 2.1 0.0049 15.9 0.0 2.2 2 0 0 2 2 2 1 ER membrane protein SH3 Pex14_N PF04695.13 KKA03502.1 - 0.73 10.5 4.9 0.19 12.4 0.5 2.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PPTA PF01239.22 KKA03503.1 - 1.2e-29 101.1 15.3 5.1e-08 32.4 0.6 4.8 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat Tail_P2_I PF09684.10 KKA03503.1 - 0.011 15.7 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) Vps53_N PF04100.12 KKA03504.1 - 2.4e-23 82.7 21.1 2.4e-23 82.7 21.1 2.8 3 0 0 3 3 3 1 Vps53-like, N-terminal VPS53_C PF16854.5 KKA03504.1 - 2.6e-06 27.5 8.4 2.6e-06 27.5 8.4 3.5 2 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus DUF445 PF04286.12 KKA03504.1 - 0.0078 16.1 2.0 0.0078 16.1 2.0 3.7 2 1 1 4 4 4 1 Protein of unknown function (DUF445) Cpn60_TCP1 PF00118.24 KKA03505.1 - 6.6e-147 490.1 9.2 7.5e-147 489.9 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 KKA03505.1 - 0.017 14.7 0.2 0.061 12.9 0.1 2.0 2 0 0 2 2 2 0 Propionate catabolism activator DrsE PF02635.15 KKA03505.1 - 0.057 13.8 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 DsrE/DsrF-like family DEAD PF00270.29 KKA03506.1 - 7.3e-46 156.1 2.1 5e-45 153.4 0.0 3.0 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKA03506.1 - 1.2e-24 86.7 0.1 6.1e-24 84.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKA03506.1 - 9e-21 73.9 0.0 2.5e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKA03506.1 - 6.4e-08 32.8 0.1 6.4e-08 32.8 0.1 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KKA03506.1 - 0.0017 18.6 0.0 0.0061 16.7 0.0 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain PPARgamma_N PF12577.8 KKA03506.1 - 0.031 14.9 0.7 3 8.6 0.2 2.7 2 0 0 2 2 2 0 PPAR gamma N-terminal region HSP70 PF00012.20 KKA03507.1 - 3.2e-261 867.8 16.1 3.7e-261 867.6 16.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKA03507.1 - 5.4e-20 71.5 6.0 6.6e-20 71.2 0.7 2.4 3 0 0 3 3 3 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KKA03507.1 - 0.00067 19.2 0.1 0.0093 15.5 0.1 2.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KKA03507.1 - 0.0027 17.0 3.2 0.064 12.5 0.1 3.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.6 KKA03507.1 - 0.0094 16.4 5.6 0.54 10.7 0.2 3.5 3 2 0 3 3 3 1 Cell division protein FtsA FGGY_C PF02782.16 KKA03507.1 - 0.018 14.8 0.0 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3153 PF11353.8 KKA03507.1 - 0.024 14.2 0.0 0.81 9.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3153) RGS12_us2 PF16611.5 KKA03507.1 - 0.043 14.2 0.6 0.17 12.3 0.6 2.0 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco DIOX_N PF14226.6 KKA03507.1 - 0.067 13.9 0.2 0.15 12.8 0.2 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Sec34 PF04136.15 KKA03507.1 - 0.16 11.8 5.5 0.072 13.0 2.7 1.8 2 0 0 2 2 2 0 Sec34-like family SHS2_FTSA PF02491.20 KKA03507.1 - 0.25 11.8 1.6 0.51 10.8 0.4 2.1 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA SBDS PF01172.18 KKA03508.1 - 5.2e-23 80.9 3.4 8.6e-23 80.2 3.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KKA03508.1 - 3.9e-14 52.7 5.3 3.9e-14 52.6 0.8 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain DUF5354 PF17305.2 KKA03508.1 - 0.0092 16.2 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5354) Abhydro_lipase PF04083.16 KKA03509.1 - 5.8e-16 57.8 0.1 1.3e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KKA03509.1 - 2.1e-09 37.4 0.0 4.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KKA03509.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 KKA03509.1 - 0.00053 19.6 0.0 0.067 12.7 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 2) LCAT PF02450.15 KKA03509.1 - 0.0034 16.6 0.1 0.0099 15.1 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KKA03509.1 - 0.012 14.9 0.0 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KKA03509.1 - 0.021 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF1749 PF08538.10 KKA03509.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKA03509.1 - 0.19 12.3 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sof1 PF04158.14 KKA03510.1 - 7e-25 87.1 15.8 1.6e-24 86.0 15.8 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KKA03510.1 - 2.8e-22 78.6 5.6 0.00063 20.5 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03510.1 - 0.0021 18.3 0.5 4.1 7.8 0.0 3.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKA03510.1 - 0.0088 15.0 0.0 2.7 6.8 0.0 2.3 1 1 1 2 2 2 2 Partner and localizer of BRCA2 WD40 domain Peptidase_S76 PF13611.6 KKA03510.1 - 0.031 14.6 0.2 0.094 13.0 0.0 1.9 1 1 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 DUF2540 PF10802.8 KKA03510.1 - 0.48 10.5 4.0 1.2 9.3 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) MBR1 PF17058.5 KKA03510.1 - 0.84 9.9 6.1 0.11 12.8 0.5 2.3 2 1 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 NIF PF03031.18 KKA03511.1 - 4.1e-48 163.1 0.5 8.3e-46 155.6 0.1 2.7 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.14 KKA03511.1 - 0.24 11.0 2.4 0.2 11.2 0.2 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HlyIII PF03006.20 KKA03513.1 - 4e-46 157.5 14.0 5.6e-46 157.0 14.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related NFRKB_winged PF14465.6 KKA03513.1 - 0.16 12.2 3.0 0.66 10.2 0.0 3.0 3 0 0 3 3 3 0 NFRKB Winged Helix-like MFS_1 PF07690.16 KKA03513.1 - 8.9 5.1 14.7 2 7.2 9.7 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily Aldedh PF00171.22 KKA03514.1 - 1e-102 344.0 0.0 1.3e-102 343.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dak1_2 PF13684.6 KKA03514.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Metal_hydrol PF10118.9 KKA03514.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase Peptidase_M1 PF01433.20 KKA03515.1 - 1.5e-76 256.8 1.6 2.6e-76 256.0 1.6 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KKA03515.1 - 8.3e-59 199.7 5.0 2.4e-58 198.2 1.4 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KKA03515.1 - 1.3e-40 139.6 3.1 1.3e-40 139.6 3.1 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Rotamase PF00639.21 KKA03516.1 - 3.2e-16 60.0 0.0 4.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KKA03516.1 - 2.6e-10 40.9 0.0 5.9e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KKA03516.1 - 3.9e-08 33.3 1.3 6.1e-08 32.6 1.3 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 KKA03516.1 - 0.055 14.3 0.0 0.085 13.7 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Peptidase_M1 PF01433.20 KKA03517.1 - 3.4e-68 229.5 2.5 8.4e-68 228.2 2.5 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KKA03517.1 - 6.6e-49 167.2 0.4 9.6e-49 166.6 0.4 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KKA03517.1 - 3.3e-36 125.2 2.6 3.3e-36 125.2 2.6 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Brr6_like_C_C PF10104.9 KKA03518.1 - 1.4e-25 89.6 7.2 1.4e-25 89.6 7.2 1.8 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldedh PF00171.22 KKA03519.1 - 3.6e-104 348.9 0.0 4.4e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4211 PF13926.6 KKA03520.1 - 0.021 14.9 0.8 0.042 13.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) RNase_PH PF01138.21 KKA03521.1 - 1.1e-09 38.9 0.0 2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKA03521.1 - 6.8e-05 22.8 0.1 0.0002 21.3 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Baculo_11_kDa PF06143.11 KKA03522.1 - 0.03 13.9 2.1 0.14 11.8 0.8 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family HIM1 PF08732.10 KKA03523.1 - 6.7e-20 71.3 0.5 3.4e-19 69.0 0.5 1.9 1 1 0 1 1 1 1 HIM1 Scs3p PF10261.9 KKA03524.1 - 5.1e-23 81.8 13.9 1.4e-17 64.1 1.9 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KKA03524.1 - 5.9e-05 22.9 2.0 5.9e-05 22.9 2.0 2.1 2 1 0 2 2 2 1 PAP2 superfamily RRF PF01765.19 KKA03525.1 - 5.8e-12 45.9 5.7 1.2e-11 44.9 5.7 1.5 1 0 0 1 1 1 1 Ribosome recycling factor CAS_C PF12026.8 KKA03525.1 - 0.085 12.9 6.6 0.75 9.9 6.6 2.1 1 1 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Cyt-b5 PF00173.28 KKA03526.1 - 3.7e-14 52.6 0.0 8.5e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HIT PF04438.16 KKA03527.1 - 5.2e-08 32.6 10.8 9.4e-08 31.8 10.8 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KKA03527.1 - 0.14 12.3 7.2 0.28 11.3 7.2 1.5 1 0 0 1 1 1 0 MYND finger RNase_PH PF01138.21 KKA03529.1 - 5.5e-20 72.2 0.1 7.6e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKA03529.1 - 0.00029 20.8 0.5 0.0023 17.9 0.0 2.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.13 KKA03530.1 - 9.6e-63 212.4 27.4 1.9e-62 211.5 27.4 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KKA03530.1 - 4.6e-16 58.8 11.6 4.6e-16 58.8 11.6 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KKA03530.1 - 4.7e-05 23.2 0.3 4.7e-05 23.2 0.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 87 PMT_2 PF13231.6 KKA03530.1 - 0.00016 21.9 12.4 0.00016 21.9 12.4 2.6 2 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4500 PF14937.6 KKA03530.1 - 0.027 14.5 2.3 0.52 10.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4500) Biotin_lipoyl PF00364.22 KKA03531.1 - 1e-18 66.9 1.9 2.1e-18 65.9 1.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKA03531.1 - 1.2e-08 35.2 0.1 4.9e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 e3 binding domain ATP-sulfurylase PF01747.17 KKA03532.1 - 6.7e-81 270.8 0.0 9.1e-81 270.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KKA03532.1 - 1.4e-41 141.8 0.0 6e-40 136.5 0.0 2.4 2 0 0 2 2 2 1 PUA-like domain Oxysterol_BP PF01237.18 KKA03533.1 - 2.6e-86 289.8 4.4 3.6e-86 289.3 1.6 2.4 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KKA03533.1 - 1.3e-18 67.0 0.0 4.5e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Foamy_BEL PF03274.14 KKA03533.1 - 0.0061 15.9 0.8 0.085 12.2 0.0 3.0 3 0 0 3 3 3 1 Foamy virus BEL 1/2 protein SQHop_cyclase_C PF13243.6 KKA03534.1 - 1e-38 133.2 0.0 6.4e-38 130.6 0.0 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KKA03534.1 - 9.9e-37 126.6 0.0 6.1e-30 104.3 0.0 3.2 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KKA03534.1 - 2.5e-26 91.1 11.4 3.4e-07 29.9 0.0 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KKA03534.1 - 0.019 14.3 0.2 5.7 6.2 0.0 3.3 2 1 1 3 3 3 0 Pectic acid lyase TED_complement PF07678.14 KKA03534.1 - 0.034 13.2 0.7 0.64 9.0 0.0 2.7 2 1 1 3 3 3 0 A-macroglobulin TED domain TPR_2 PF07719.17 KKA03535.1 - 0.026 14.6 0.1 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Transp_cyt_pur PF02133.15 KKA03536.1 - 8.2e-27 94.0 40.1 2.4e-26 92.5 40.1 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UPF0139 PF03669.13 KKA03536.1 - 0.8 9.6 0.0 0.8 9.6 0.0 4.2 3 2 2 5 5 5 0 Uncharacterised protein family (UPF0139) SUI1 PF01253.22 KKA03537.1 - 7.9e-16 58.3 2.0 1.1e-15 57.9 0.6 2.1 1 1 1 2 2 2 1 Translation initiation factor SUI1 DUF262 PF03235.14 KKA03537.1 - 0.46 10.6 9.4 0.49 10.5 8.9 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF262 Fmp27_WPPW PF10359.9 KKA03537.1 - 1.6 7.5 12.3 1.4 7.7 11.3 1.2 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PP2C PF00481.21 KKA03538.1 - 1.9e-45 155.5 0.2 3.6e-45 154.6 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KKA03538.1 - 1.4e-42 143.3 86.4 7.6e-12 44.8 5.0 10.6 8 3 2 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 KKA03538.1 - 2.2e-40 136.0 86.3 3.5e-06 27.3 4.6 12.9 4 2 11 16 16 16 14 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KKA03538.1 - 1.2e-27 96.7 0.0 3.9e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KKA03538.1 - 1.1e-07 31.6 35.6 0.00017 21.2 0.8 6.1 3 2 3 6 6 6 4 Leucine-rich repeat SYS1 PF09801.9 KKA03539.1 - 1.1e-38 132.6 13.7 1.3e-38 132.4 13.7 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF5412 PF17428.2 KKA03539.1 - 1.8 8.5 0.0 1.8 8.5 0.0 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5412) Aminotran_1_2 PF00155.21 KKA03540.1 - 1.8e-20 73.5 0.1 1.5e-19 70.5 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KKA03540.1 - 0.0029 16.4 0.2 0.015 14.0 0.2 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KKA03540.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2183 PF09949.9 KKA03541.1 - 0.0012 19.1 0.1 0.0034 17.7 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) MDM31_MDM32 PF08118.11 KKA03542.1 - 5.1e-174 579.8 12.3 1.3e-172 575.2 12.3 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins ASPRs PF17641.2 KKA03542.1 - 3.9 7.8 5.9 3.5 8.0 1.7 2.6 2 1 0 2 2 2 0 Ancylostoma-associated secreted protein related Steroid_dh PF02544.16 KKA03543.1 - 6.2e-08 32.7 13.3 6.2e-08 32.7 13.3 2.0 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Cation_ATPase_C PF00689.21 KKA03543.1 - 8 6.1 11.8 0.43 10.3 4.5 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Pribosyltran PF00156.27 KKA03545.1 - 6.7e-08 32.2 0.0 9.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SUKH_6 PF14568.6 KKA03545.1 - 0.0088 16.5 0.3 2.1 8.8 0.3 3.0 2 1 0 2 2 2 1 SMI1-KNR4 cell-wall TcpE PF12648.7 KKA03545.1 - 0.032 14.7 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 TcpE family CCDC-167 PF15188.6 KKA03545.1 - 0.044 14.1 0.6 0.083 13.2 0.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 S1_2 PF13509.6 KKA03545.1 - 0.12 12.5 0.5 0.32 11.1 0.4 1.7 2 0 0 2 2 2 0 S1 domain FleQ PF06490.11 KKA03545.1 - 0.14 12.6 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Polo_box_2 PF18531.1 KKA03545.1 - 0.96 9.6 3.1 3 8.0 0.2 2.6 2 1 1 3 3 3 0 Polo box domain TMF_TATA_bd PF12325.8 KKA03546.1 - 3.5e-09 36.9 12.9 3.5e-09 36.9 12.9 6.8 3 2 4 7 7 7 2 TATA element modulatory factor 1 TATA binding Rab5ip PF07019.12 KKA03547.1 - 1.8e-13 50.8 3.7 2.4e-13 50.5 3.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PUF PF00806.19 KKA03548.1 - 2.4e-48 159.2 20.2 1.2e-07 31.1 0.2 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Toxin_38 PF14866.6 KKA03548.1 - 0.022 15.1 2.3 1.2 9.5 0.1 3.4 3 0 0 3 3 3 0 Potassium channel toxin Flu_M1 PF00598.19 KKA03548.1 - 0.062 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) LSM PF01423.22 KKA03549.1 - 4e-12 45.7 1.8 9e-12 44.5 1.8 1.6 1 0 0 1 1 1 1 LSM domain DUF5584 PF17822.1 KKA03549.1 - 0.044 13.3 0.2 0.044 13.3 0.2 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5584) ETF PF01012.21 KKA03550.1 - 1.8e-29 102.9 0.0 2.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain NUDIX PF00293.28 KKA03551.1 - 5.9e-07 29.6 0.3 0.0091 16.0 0.2 3.0 2 1 1 3 3 3 2 NUDIX domain Flocculin PF00624.18 KKA03552.1 - 7.6e-15 54.9 253.8 3.5e-05 23.9 22.6 18.1 14 2 1 15 15 15 11 Flocculin repeat GLEYA PF10528.9 KKA03552.1 - 6.3e-06 26.5 0.1 6.3e-06 26.5 0.1 3.8 3 1 0 3 3 3 1 GLEYA domain IPK PF03770.16 KKA03553.1 - 2.5e-43 148.3 0.9 3.5e-43 147.8 0.9 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GTP_EFTU PF00009.27 KKA03554.1 - 8e-45 152.8 0.0 1.5e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKA03554.1 - 6.6e-33 113.4 1.4 3e-32 111.2 1.4 2.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKA03554.1 - 7.5e-09 35.9 2.1 2.2e-08 34.3 2.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKA03554.1 - 0.0016 18.5 0.2 0.0085 16.2 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 KKA03554.1 - 0.09 13.1 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain Herpes_UL17 PF04559.12 KKA03554.1 - 9.4 4.9 11.0 14 4.4 11.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein GTP_CH_N PF12471.8 KKA03555.1 - 8.5e-70 234.4 0.0 1.3e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KKA03555.1 - 1e-12 47.9 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II AMP-binding PF00501.28 KKA03556.1 - 2.7e-88 296.4 0.0 3.3e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKA03556.1 - 8.7e-22 77.9 0.0 2.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KKA03556.1 - 1.3e-19 69.8 0.9 3.3e-19 68.5 0.9 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Mem_trans PF03547.18 KKA03557.1 - 1.3e-34 119.2 0.7 9.4e-34 116.4 0.6 2.3 1 1 0 1 1 1 1 Membrane transport protein PI3K_1B_p101 PF10486.9 KKA03557.1 - 0.21 9.4 8.3 0.27 9.0 8.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Brr6_like_C_C PF10104.9 KKA03557.1 - 8.1 6.2 6.8 8.6 6.1 0.3 3.4 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Stb3 PF10330.9 KKA03558.1 - 1.1e-12 47.8 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein Phage_fiber_2 PF03406.13 KKA03558.1 - 0.1 12.2 0.5 0.62 9.7 0.0 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat CDC37_N PF03234.14 KKA03560.1 - 1.7e-39 135.7 9.3 1.7e-39 135.7 9.3 3.5 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KKA03560.1 - 4.9e-25 87.7 2.9 4.9e-25 87.7 2.9 2.7 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KKA03560.1 - 1.2e-17 63.9 5.1 1.2e-17 63.9 5.1 3.3 4 0 0 4 4 4 1 Cdc37 C terminal domain FucT_N PF18025.1 KKA03560.1 - 0.023 15.1 2.6 0.063 13.7 0.2 2.9 3 0 0 3 3 3 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain ABC2_membrane_3 PF12698.7 KKA03560.1 - 0.18 10.9 7.7 0.11 11.6 2.2 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein TFIID_30kDa PF03540.13 KKA03561.1 - 5.8e-20 71.0 0.1 1.2e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_60s PF00428.19 KKA03561.1 - 0.18 12.4 3.3 12 6.5 0.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein NapB PF03892.14 KKA03561.1 - 1.9 8.5 5.8 0.37 10.8 0.2 2.3 2 1 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Pep3_Vps18 PF05131.14 KKA03562.1 - 6.6e-11 42.2 6.3 6.6e-11 42.2 6.3 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 KKA03562.1 - 0.0077 16.7 2.3 0.0077 16.7 2.3 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 ID PF18543.1 KKA03562.1 - 0.061 13.3 2.2 0.7 10.0 0.3 2.9 2 0 0 2 2 2 0 Intracellular delivery domain zf-RING_2 PF13639.6 KKA03562.1 - 1.2 9.6 9.2 4 7.9 6.0 2.4 2 0 0 2 2 2 0 Ring finger domain Pro_isomerase PF00160.21 KKA03563.1 - 2.2e-45 154.8 0.1 2.4e-45 154.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Semialdhyde_dhC PF02774.18 KKA03564.1 - 1.3e-43 149.2 0.0 1.8e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KKA03564.1 - 1.9e-32 112.2 0.0 4e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KKA03564.1 - 0.0029 18.3 0.0 0.0092 16.7 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KKA03564.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 KKA03564.1 - 0.021 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KKA03564.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_16 PF10294.9 KKA03565.1 - 1.4e-09 37.9 1.0 2.1e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Chalcone PF02431.15 KKA03565.1 - 0.019 14.4 0.4 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Chalcone-flavanone isomerase DUF2600 PF10776.9 KKA03565.1 - 0.036 12.9 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) SAC3_GANP PF03399.16 KKA03566.1 - 2.9e-82 276.4 0.3 4.1e-82 275.9 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP family Pro_dh PF01619.18 KKA03568.1 - 2.1e-55 188.4 0.1 2.6e-55 188.1 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Cytokin_check_N PF10407.9 KKA03568.1 - 0.018 15.0 0.7 0.14 12.2 0.2 2.5 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus TrwB_AAD_bind PF10412.9 KKA03569.1 - 0.073 12.0 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SH3_1 PF00018.28 KKA03570.1 - 4.7e-11 42.1 0.1 4.7e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKA03570.1 - 6.6e-11 41.9 0.1 1.4e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKA03570.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF5599 PF18141.1 KKA03570.1 - 0.026 14.7 0.0 0.049 13.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5599) Ribosomal_L18_c PF14204.6 KKA03571.1 - 0.095 13.6 0.1 2.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Ureide_permease PF07168.11 KKA03572.1 - 0.095 11.4 1.4 0.11 11.3 1.4 1.1 1 0 0 1 1 1 0 Ureide permease DUF2529 PF10740.9 KKA03572.1 - 0.097 12.3 0.1 0.097 12.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) End_N_terminal PF12218.8 KKA03572.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase LSM PF01423.22 KKA03572.1 - 0.58 9.9 0.1 0.58 9.9 0.1 3.4 3 2 1 4 4 4 0 LSM domain Sec1 PF00995.23 KKA03575.1 - 6.4e-76 256.8 27.4 7.7e-76 256.5 27.4 1.1 1 0 0 1 1 1 1 Sec1 family Diphthami_syn_2 PF01902.17 KKA03576.1 - 6.7e-31 107.5 0.2 4.7e-30 104.7 0.2 2.1 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KKA03576.1 - 1.5e-12 47.6 0.0 1.8e-08 34.4 0.0 3.3 3 0 0 3 3 3 3 Endoribonuclease L-PSP ENTH PF01417.20 KKA03577.1 - 6.8e-24 84.3 1.6 1.3e-23 83.4 1.6 1.5 1 0 0 1 1 1 1 ENTH domain PGA2 PF07543.12 KKA03577.1 - 3.3 7.7 12.2 0.16 11.9 5.3 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 TMEM51 PF15345.6 KKA03577.1 - 7.7 6.3 11.6 1 9.1 6.0 2.2 2 1 1 3 3 3 0 Transmembrane protein 51 RWD PF05773.22 KKA03578.1 - 2.8e-08 34.1 8.8 1.7e-07 31.5 8.8 2.3 1 1 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KKA03578.1 - 5.7e-05 23.5 3.1 5.7e-05 23.5 3.1 2.7 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Glyco_hydro81C PF17652.1 KKA03579.1 - 9e-118 393.5 16.9 1.4e-117 392.9 16.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KKA03579.1 - 3.8e-26 92.0 9.1 4.9e-25 88.4 5.6 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain MFS_1 PF07690.16 KKA03580.1 - 3.7e-13 49.1 12.8 3.7e-13 49.1 12.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_C74 PF12387.8 KKA03580.1 - 0.11 11.9 1.3 0.33 10.4 1.3 1.8 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Mcp5_PH PF12814.7 KKA03581.1 - 2e-36 124.8 1.3 5.5e-36 123.4 0.1 2.5 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF4478 PF14793.6 KKA03581.1 - 0.017 15.0 0.1 4 7.4 0.0 3.8 3 0 0 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF723 PF05265.13 KKA03581.1 - 0.033 14.1 2.3 11 6.1 0.0 4.8 6 0 0 6 6 6 0 Protein of unknown function (DUF723) YrzK PF17449.2 KKA03581.1 - 0.084 13.2 0.3 0.3 11.4 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized YrzK-like 2-oxoacid_dh PF00198.23 KKA03583.1 - 4.4e-79 265.2 0.0 7e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKA03583.1 - 2.9e-34 116.7 7.5 4.3e-17 61.7 1.6 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KKA03583.1 - 3.3e-08 33.2 0.5 0.22 11.4 0.0 4.3 2 2 2 4 4 4 3 Biotin-lipoyl like HlyD_3 PF13437.6 KKA03583.1 - 3.5e-06 27.7 0.9 1.7 9.4 0.0 4.3 1 1 3 4 4 4 2 HlyD family secretion protein GCV_H PF01597.19 KKA03583.1 - 6.7e-05 22.8 9.1 0.0083 16.0 0.2 3.0 3 0 0 3 3 3 2 Glycine cleavage H-protein RnfC_N PF13375.6 KKA03583.1 - 0.00047 20.1 0.2 0.11 12.5 0.1 2.7 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 KKA03583.1 - 0.015 14.9 0.1 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2922 PF11148.8 KKA03583.1 - 0.048 13.4 0.2 2.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) DUF2254 PF10011.9 KKA03583.1 - 0.059 12.2 0.2 0.2 10.4 0.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) DUF2118 PF09891.9 KKA03583.1 - 0.068 13.1 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M22 PF00814.25 KKA03584.1 - 1.1e-51 176.2 0.0 1.4e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family PTB PF08416.13 KKA03584.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotyrosine-binding domain Choline_kinase PF01633.20 KKA03585.1 - 7.6e-58 195.6 0.3 1.4e-57 194.7 0.3 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KKA03585.1 - 2.8e-08 34.0 0.0 1.1e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.14 KKA03585.1 - 0.0056 16.3 0.3 0.014 15.0 0.3 1.7 1 0 0 1 1 1 1 Choline kinase N terminus zf-H2C2_2 PF13465.6 KKA03586.1 - 1.3e-05 25.4 9.4 0.026 14.9 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA03586.1 - 4.8e-05 23.8 17.1 0.045 14.6 1.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KKA03586.1 - 0.002 18.5 18.8 0.085 13.3 1.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type FlhC PF05280.11 KKA03586.1 - 0.093 12.4 1.0 0.18 11.5 1.0 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) zf-C2H2_8 PF15909.5 KKA03586.1 - 0.36 11.2 9.8 0.21 11.9 2.1 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zinc_ribbon_4 PF13717.6 KKA03586.1 - 2 8.4 4.8 0.69 9.9 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.12 KKA03586.1 - 4.5 7.8 10.7 11 6.6 6.3 2.5 1 1 1 2 2 2 0 CHY zinc finger WD40 PF00400.32 KKA03587.1 - 1.1e-41 140.1 16.1 6.2e-06 26.8 0.2 9.4 9 0 0 9 9 9 7 WD domain, G-beta repeat Utp12 PF04003.12 KKA03587.1 - 9.8e-16 58.0 3.2 2.3e-15 56.8 3.2 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKA03587.1 - 1.2e-11 44.8 5.1 0.01 16.1 0.0 7.5 5 2 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKA03587.1 - 1.3e-07 31.3 11.4 0.0014 18.0 0.1 4.3 3 2 1 4 4 4 3 WD40-like domain DUF2457 PF10446.9 KKA03587.1 - 0.063 12.4 5.5 0.1 11.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Lipoprot_C PF08794.10 KKA03588.1 - 0.046 13.7 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like Aldo_ket_red PF00248.21 KKA03589.1 - 1e-47 162.8 0.2 5e-46 157.2 0.2 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Homeodomain PF00046.29 KKA03589.1 - 0.13 12.2 0.1 32 4.5 0.0 3.0 3 0 0 3 3 3 0 Homeodomain AAA_5 PF07728.14 KKA03590.1 - 9.8e-15 54.8 0.0 1.9e-08 34.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KKA03590.1 - 6.2e-09 36.0 0.0 2.3e-08 34.2 0.0 2.1 1 0 0 1 1 1 1 Midasin AAA lid domain Dynein_heavy PF03028.15 KKA03590.1 - 1.1e-06 28.8 1.0 7.1e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KKA03591.1 - 3.8e-85 282.8 1.8 1.6e-21 76.8 0.0 6.5 6 0 0 6 6 6 6 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KKA03591.1 - 4.4e-31 107.2 1.1 6.5e-15 55.2 0.1 3.3 3 0 0 3 3 2 2 Midasin AAA lid domain AAA_lid_5 PF17865.1 KKA03591.1 - 7.5e-29 99.9 0.0 3.9e-28 97.6 0.0 2.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_7 PF12775.7 KKA03591.1 - 3.7e-25 88.5 13.5 1.2e-07 31.4 0.2 4.9 5 0 0 5 5 4 4 P-loop containing dynein motor region Sigma54_activat PF00158.26 KKA03591.1 - 4.8e-22 78.4 0.1 5.2e-08 32.8 0.0 5.0 5 0 0 5 5 4 4 Sigma-54 interaction domain AAA_3 PF07726.11 KKA03591.1 - 2.9e-20 72.5 0.1 2.3e-05 24.3 0.0 5.9 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKA03591.1 - 7.8e-19 68.7 11.9 0.0003 21.2 0.1 6.4 4 2 1 5 5 5 4 AAA ATPase domain AAA PF00004.29 KKA03591.1 - 7.2e-18 65.3 3.2 0.00017 22.0 0.0 5.3 4 1 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KKA03591.1 - 6e-16 58.3 1.0 0.0042 16.1 0.0 6.7 5 3 0 5 5 5 4 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 KKA03591.1 - 6.8e-16 58.5 0.0 0.023 14.4 0.0 5.7 5 1 0 5 5 5 4 AAA domain TsaE PF02367.17 KKA03591.1 - 1.4e-13 51.0 0.9 0.0099 15.9 0.1 4.7 4 0 0 4 4 4 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKA03591.1 - 3.3e-13 50.3 9.7 0.00018 22.1 0.0 4.9 4 1 0 4 4 4 3 ABC transporter T2SSE PF00437.20 KKA03591.1 - 6.8e-13 48.3 6.4 0.00094 18.3 0.0 4.3 4 0 0 4 4 4 4 Type II/IV secretion system protein Dynein_heavy PF03028.15 KKA03591.1 - 7.3e-13 48.7 0.1 0.0062 16.6 0.0 6.3 5 1 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KKA03591.1 - 1.2e-12 48.2 11.3 0.0078 16.5 0.1 5.8 5 1 0 5 5 5 3 AAA domain AAA_14 PF13173.6 KKA03591.1 - 1.3e-12 47.9 12.6 0.0012 18.9 0.0 6.6 6 1 0 6 6 5 4 AAA domain Sigma54_activ_2 PF14532.6 KKA03591.1 - 3.2e-12 46.7 1.8 0.016 15.3 0.0 5.0 4 1 0 4 4 4 2 Sigma-54 interaction domain AAA_18 PF13238.6 KKA03591.1 - 4.1e-11 43.6 1.3 0.25 11.9 0.0 5.1 4 0 0 4 4 4 3 AAA domain Mg_chelatase PF01078.21 KKA03591.1 - 5.6e-11 42.2 0.9 0.57 9.5 0.0 7.1 6 1 1 7 7 7 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKA03591.1 - 2.5e-10 40.7 1.8 0.28 11.6 0.0 5.3 4 0 0 4 4 4 2 RNA helicase NACHT PF05729.12 KKA03591.1 - 4e-10 39.9 1.1 0.037 13.9 0.0 5.0 4 0 0 4 4 4 3 NACHT domain AAA_2 PF07724.14 KKA03591.1 - 8.1e-10 39.1 0.6 0.64 10.1 0.0 4.9 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) AAA_29 PF13555.6 KKA03591.1 - 2.9e-09 36.5 1.2 0.14 11.9 0.0 4.5 4 0 0 4 4 4 2 P-loop containing region of AAA domain ATPase_2 PF01637.18 KKA03591.1 - 3.9e-09 36.8 0.2 0.68 9.8 0.0 4.8 4 0 0 4 4 4 2 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KKA03591.1 - 5.4e-09 36.2 12.5 0.025 14.5 0.5 4.9 5 0 0 5 5 4 3 RsgA GTPase AAA_19 PF13245.6 KKA03591.1 - 5.7e-09 36.5 7.7 0.068 13.5 0.1 5.1 4 2 1 5 5 4 3 AAA domain AAA_33 PF13671.6 KKA03591.1 - 7.7e-09 35.8 3.2 0.12 12.6 0.3 5.2 4 1 0 4 4 4 2 AAA domain DUF815 PF05673.13 KKA03591.1 - 2.3e-08 33.5 2.0 0.11 11.6 0.0 4.9 4 0 0 4 4 4 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KKA03591.1 - 2.6e-08 33.4 1.6 1.7 7.9 0.0 5.2 5 1 0 5 5 4 2 Zeta toxin Rad17 PF03215.15 KKA03591.1 - 4.8e-08 33.1 9.3 0.037 13.9 0.1 5.6 5 1 0 5 5 4 2 Rad17 P-loop domain ResIII PF04851.15 KKA03591.1 - 5.4e-08 33.0 6.2 0.061 13.3 2.6 4.6 4 1 0 4 4 4 2 Type III restriction enzyme, res subunit TniB PF05621.11 KKA03591.1 - 9.7e-08 31.6 0.4 0.5 9.7 0.0 4.5 4 0 0 4 4 4 2 Bacterial TniB protein PduV-EutP PF10662.9 KKA03591.1 - 1.3e-07 31.5 2.0 0.2 11.4 0.1 4.6 4 0 0 4 4 4 2 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KKA03591.1 - 1.3e-07 31.5 0.1 0.03 14.0 0.0 3.4 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 KKA03591.1 - 2.6e-07 30.5 0.6 0.65 9.7 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein MCM PF00493.23 KKA03591.1 - 3.2e-07 29.7 2.7 0.44 9.6 0.2 4.4 4 0 0 4 4 4 1 MCM P-loop domain Bac_DnaA PF00308.18 KKA03591.1 - 8.8e-07 29.0 0.7 0.18 11.6 0.0 4.3 4 0 0 4 4 3 1 Bacterial dnaA protein NB-ARC PF00931.22 KKA03591.1 - 2.3e-06 27.0 2.8 1.2 8.2 0.1 4.3 4 0 0 4 4 4 3 NB-ARC domain AAA_25 PF13481.6 KKA03591.1 - 2.4e-06 27.3 0.0 0.12 11.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KKA03591.1 - 2.6e-06 27.5 8.7 0.28 11.1 0.1 4.3 4 0 0 4 4 4 2 NTPase RuvB_N PF05496.12 KKA03591.1 - 2.6e-06 27.3 0.5 0.083 12.6 0.0 5.0 5 0 0 5 5 5 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KKA03591.1 - 5.3e-06 26.0 0.2 1.5 8.2 0.0 3.9 4 0 0 4 4 3 1 PhoH-like protein Roc PF08477.13 KKA03591.1 - 6.2e-06 26.4 5.6 3.1 8.0 0.1 4.9 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 KKA03591.1 - 7.1e-06 25.9 1.1 2 8.2 0.0 4.8 4 1 0 4 4 4 1 DEAD/DEAH box helicase AAA_24 PF13479.6 KKA03591.1 - 1.1e-05 25.2 1.3 1.1 9.0 0.2 4.5 4 1 0 4 4 4 1 AAA domain cobW PF02492.19 KKA03591.1 - 1.2e-05 25.0 3.5 0.048 13.2 0.0 4.4 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KKA03591.1 - 2.2e-05 24.2 3.9 0.64 9.6 0.2 4.3 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KKA03591.1 - 6.5e-05 23.2 4.0 3.1 8.0 0.0 4.4 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 KKA03591.1 - 0.00011 21.7 0.1 2.4 7.5 0.0 3.8 3 0 0 3 3 3 1 KaiC AAA_11 PF13086.6 KKA03591.1 - 0.00018 21.4 8.3 2.1 8.1 0.0 4.8 4 1 0 4 4 4 1 AAA domain dNK PF01712.19 KKA03591.1 - 0.00044 20.2 3.6 4.2 7.2 0.0 4.7 4 0 0 4 4 4 0 Deoxynucleoside kinase AAA_23 PF13476.6 KKA03591.1 - 0.00056 20.5 28.1 0.028 14.9 1.6 5.7 5 2 0 5 5 4 2 AAA domain Viral_helicase1 PF01443.18 KKA03591.1 - 0.00065 19.5 6.4 0.45 10.2 0.1 5.0 6 0 0 6 6 4 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 KKA03591.1 - 0.0014 17.9 0.6 2.1 7.5 0.0 3.9 4 0 0 4 4 4 1 TIP49 P-loop domain ATP_bind_1 PF03029.17 KKA03591.1 - 0.0015 18.4 9.8 1.1 8.9 0.2 5.0 5 0 0 5 5 4 1 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 KKA03591.1 - 0.0018 17.3 0.9 3.1 6.6 0.1 3.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.10 KKA03591.1 - 0.0029 17.1 2.9 14 5.0 0.0 4.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit DUF853 PF05872.12 KKA03591.1 - 0.0036 16.0 2.5 2.9 6.4 0.0 3.7 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 KKA03591.1 - 0.012 15.0 2.4 4.4 6.6 0.1 3.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family PRK PF00485.18 KKA03591.1 - 0.017 14.9 5.8 7 6.3 0.0 4.5 5 0 0 5 5 4 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 KKA03591.1 - 0.026 14.2 2.1 9.5 5.8 0.0 3.9 3 0 0 3 3 3 0 Thymidylate kinase CbiA PF01656.23 KKA03591.1 - 0.051 13.6 0.5 9.4 6.3 0.0 3.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KKA03591.1 - 0.074 12.0 0.1 3.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DLIC PF05783.11 KKA03591.1 - 0.076 11.8 3.4 6.8 5.4 0.1 3.5 4 0 0 4 4 4 0 Dynein light intermediate chain (DLIC) DUF87 PF01935.17 KKA03591.1 - 0.11 12.6 17.5 11 6.0 0.0 5.8 4 1 0 4 4 4 0 Helicase HerA, central domain SKI PF01202.22 KKA03591.1 - 0.11 12.6 0.3 4.3 7.4 0.0 3.0 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.14 KKA03591.1 - 0.13 12.1 8.4 5.2 7.0 0.2 4.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B CPT PF07931.12 KKA03591.1 - 0.18 11.6 1.1 42 3.9 0.1 4.3 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein Ras PF00071.22 KKA03591.1 - 0.21 11.2 3.4 27 4.3 0.0 4.1 4 0 0 4 4 4 0 Ras family Guanylate_kin PF00625.21 KKA03591.1 - 0.27 10.9 3.2 13 5.4 0.1 4.1 4 0 0 4 4 4 0 Guanylate kinase AAA_17 PF13207.6 KKA03591.1 - 0.35 11.3 1.0 99 3.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain Mur_ligase_M PF08245.12 KKA03591.1 - 2.6 8.0 6.9 11 5.9 0.0 3.4 3 1 0 3 3 2 0 Mur ligase middle domain CHORD PF04968.12 KKA03592.1 - 0.00021 22.0 10.6 0.00085 20.0 10.6 2.1 1 1 0 1 1 1 1 CHORD GEP5 PF17053.5 KKA03592.1 - 0.037 13.9 1.2 0.073 12.9 1.2 1.5 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 DNA_pol_A_exo1 PF01612.20 KKA03592.1 - 0.044 13.5 0.1 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 3'-5' exonuclease BTB_2 PF02214.22 KKA03593.1 - 8.2e-11 42.1 1.6 3.9e-05 23.9 0.2 3.5 2 2 0 2 2 2 2 BTB/POZ domain DUF3136 PF11334.8 KKA03594.1 - 0.11 12.2 0.1 0.56 10.0 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) KRE9 PF05390.11 KKA03595.1 - 3e-29 101.8 13.6 7.6e-29 100.5 13.6 1.7 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KKA03595.1 - 3.2e-13 50.3 0.1 3.2e-13 50.3 0.1 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Flocculin_t3 PF13928.6 KKA03596.1 - 4.2e-13 49.6 24.7 4.2e-13 49.6 24.7 1.9 3 0 0 3 3 3 1 Flocculin type 3 repeat Peptidase_S8 PF00082.22 KKA03596.1 - 0.059 12.6 1.7 0.069 12.4 1.7 1.2 1 0 0 1 1 1 0 Subtilase family Pkinase PF00069.25 KKA03597.1 - 1e-61 208.6 0.0 7.3e-61 205.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03597.1 - 9.4e-32 110.3 0.0 1.2e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKA03597.1 - 5.1e-06 25.7 0.1 7.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKA03597.1 - 3.5e-05 23.3 0.1 9.7e-05 21.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKA03597.1 - 0.00069 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKA03597.1 - 0.01 15.2 0.1 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KKA03597.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KKA03597.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ABC_membrane PF00664.23 KKA03598.1 - 9.7e-82 274.7 37.8 2.9e-48 164.9 14.6 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKA03598.1 - 1.9e-43 148.3 1.5 2e-27 96.4 0.2 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KKA03598.1 - 6e-06 25.8 5.5 0.045 13.2 3.7 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KKA03598.1 - 0.00011 22.7 0.1 0.00032 21.1 0.1 1.8 2 0 0 2 2 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KKA03598.1 - 0.00034 20.7 2.7 0.0026 17.8 1.2 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 KKA03598.1 - 0.011 15.4 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 KKA03598.1 - 0.075 12.9 0.1 0.86 9.5 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 KKA03598.1 - 0.084 13.3 0.1 5 7.6 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KKA03598.1 - 0.11 12.2 0.3 0.4 10.4 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKA03598.1 - 0.15 12.4 0.2 1.3 9.3 0.2 2.5 1 1 0 1 1 1 0 AAA domain P3A PF08727.11 KKA03598.1 - 0.54 9.7 2.1 11 5.5 0.2 2.8 2 0 0 2 2 2 0 Poliovirus 3A protein like AAA_29 PF13555.6 KKA03598.1 - 0.81 9.5 2.6 3.2 7.6 0.2 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF87 PF01935.17 KKA03598.1 - 5.2 7.1 7.9 0.41 10.7 0.7 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AIG1 PF04548.16 KKA03598.1 - 7 5.9 10.3 19 4.5 0.1 4.0 4 0 0 4 4 4 0 AIG1 family Asp PF00026.23 KKA03599.1 - 6.2e-49 167.1 0.1 6.2e-49 167.1 0.1 2.8 2 2 0 2 2 2 1 Eukaryotic aspartyl protease Flocculin_t3 PF13928.6 KKA03599.1 - 6.6e-15 55.4 17.7 6.6e-15 55.4 17.7 5.4 3 1 1 4 4 4 1 Flocculin type 3 repeat Lactamase_B_6 PF16661.5 KKA03600.1 - 1.2e-33 116.1 1.8 3.6e-33 114.6 1.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KKA03600.1 - 3.2e-12 47.0 0.1 3.2e-12 47.0 0.1 3.8 3 1 1 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Lipase_3 PF01764.25 KKA03600.1 - 0.12 12.3 0.0 0.49 10.3 0.0 2.0 1 0 0 1 1 1 0 Lipase (class 3) UvrB PF12344.8 KKA03600.1 - 0.6 10.0 6.1 0.11 12.4 0.9 2.4 3 0 0 3 3 3 0 Ultra-violet resistance protein B SF1-HH PF16275.5 KKA03601.1 - 1.5e-20 73.6 2.3 1.5e-20 73.6 2.3 2.2 2 1 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KKA03601.1 - 2.6e-07 30.4 0.0 8.4e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 KKA03601.1 - 0.0012 18.8 12.4 0.16 12.1 3.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KKA03601.1 - 0.0033 17.3 0.5 0.0033 17.3 0.5 2.7 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 KKA03601.1 - 0.0064 16.3 11.1 0.019 14.8 2.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KKA03601.1 - 0.09 12.5 7.0 2.2 8.1 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.12 KKA03601.1 - 0.13 12.2 3.2 0.27 11.3 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbons PNP_UDP_1 PF01048.20 KKA03604.1 - 2.1e-34 118.8 0.0 2.5e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Gp-FAR-1 PF05823.12 KKA03604.1 - 0.051 13.9 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3274 PF11678.8 KKA03604.1 - 0.21 10.8 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) CHCH PF06747.13 KKA03605.1 - 1.2e-07 31.6 9.7 0.033 14.3 0.1 3.5 3 1 0 3 3 3 3 CHCH domain CX9C PF16860.5 KKA03605.1 - 0.00022 21.2 16.8 0.0014 18.6 5.2 2.9 1 1 2 3 3 3 3 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KKA03605.1 - 0.0019 18.2 13.5 0.015 15.3 7.5 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 KKA03605.1 - 0.0021 18.5 10.3 0.0074 16.7 6.5 2.4 1 1 1 2 2 2 1 GCK domain DUF3716 PF12511.8 KKA03605.1 - 0.019 15.0 4.2 2.9 8.0 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3716) BORCS8 PF10167.9 KKA03605.1 - 0.022 14.7 3.3 0.028 14.3 2.9 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 8 UPF0203 PF05254.12 KKA03605.1 - 0.022 15.0 12.7 0.75 10.1 2.1 3.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KKA03605.1 - 0.043 14.0 2.8 0.043 14.0 2.8 2.5 1 1 2 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 KKA03605.1 - 0.045 14.1 5.3 3.3 8.1 4.2 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KKA03605.1 - 0.12 12.7 8.7 1.2 9.5 8.7 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 MTS PF05175.14 KKA03606.1 - 1.3e-09 37.8 0.0 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_18 PF12847.7 KKA03606.1 - 0.023 14.6 0.0 0.061 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KKA03606.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-RING_2 PF13639.6 KKA03607.1 - 9.6e-09 35.4 3.7 4.7e-07 30.0 0.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KKA03607.1 - 4.6e-07 30.0 1.4 1.2e-06 28.7 0.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KKA03607.1 - 1.2e-06 28.3 0.5 1.2e-06 28.3 0.5 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKA03607.1 - 1e-05 25.4 0.5 0.00098 19.1 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKA03607.1 - 3.2e-05 23.7 3.6 4.4e-05 23.2 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKA03607.1 - 8.1e-05 22.4 2.0 0.0002 21.1 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKA03607.1 - 9.3e-05 22.3 1.9 0.00052 19.9 0.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKA03607.1 - 0.00025 20.8 2.7 0.00057 19.7 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KKA03607.1 - 0.00094 19.2 0.5 0.0065 16.5 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KKA03607.1 - 0.012 15.4 0.2 0.034 13.9 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YceD PF02620.17 KKA03607.1 - 0.026 14.7 3.1 0.64 10.2 0.6 2.7 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD zf-RING_6 PF14835.6 KKA03607.1 - 0.05 13.5 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein CMAS PF02353.20 KKA03607.1 - 0.086 12.1 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S48 PF03574.15 KKA03607.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase family S48 zf-RING_11 PF17123.5 KKA03607.1 - 0.17 11.6 1.7 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KKA03607.1 - 0.54 10.5 5.8 0.059 13.5 1.4 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKA03607.1 - 1.7 8.8 4.1 77 3.6 1.9 3.3 2 1 0 2 2 2 0 FANCL C-terminal domain KRTDAP PF15200.6 KKA03608.1 - 0.02 14.7 0.6 0.07 12.9 0.1 2.2 3 0 0 3 3 3 0 Keratinocyte differentiation-associated Lge1 PF11488.8 KKA03608.1 - 0.039 14.1 7.2 3.4 7.9 3.8 2.6 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 PHM7_cyt PF14703.6 KKA03608.1 - 0.11 12.7 2.8 0.14 12.3 2.8 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PCRF PF03462.18 KKA03608.1 - 0.19 11.6 2.4 0.26 11.1 1.2 1.7 1 1 1 2 2 2 0 PCRF domain Dopey_N PF04118.14 KKA03609.1 - 1.3e-44 152.6 6.1 1.3e-44 152.6 6.1 5.4 5 3 0 5 5 5 2 Dopey, N-terminal NdhM PF10664.9 KKA03609.1 - 0.2 12.0 2.1 1.1 9.5 0.1 3.3 3 0 0 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M PWI PF01480.17 KKA03610.1 - 0.98 9.8 9.8 2.5 8.5 3.0 3.7 3 1 0 3 3 3 0 PWI domain RIH_assoc PF08454.11 KKA03610.1 - 6 6.8 14.6 9.1 6.2 3.2 3.7 2 2 0 2 2 2 0 RyR and IP3R Homology associated Avl9 PF09794.9 KKA03611.1 - 1.4e-30 106.2 14.7 7.6e-24 84.1 8.1 2.3 2 0 0 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 KKA03611.1 - 1.9e-11 44.1 7.4 7.5e-11 42.1 3.2 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 KKA03611.1 - 0.06 13.8 0.1 0.06 13.8 0.1 4.4 3 1 2 5 5 5 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Asp PF00026.23 KKA03613.1 - 1.8e-65 221.5 21.7 2.3e-58 198.1 8.5 3.2 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKA03613.1 - 1e-06 29.1 12.5 3.4e-06 27.4 2.8 3.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KKA03613.1 - 0.00026 21.5 0.0 0.42 11.2 0.0 3.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKA03613.1 - 0.009 16.6 0.1 10 6.9 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease Peptidase_U4 PF03419.13 KKA03613.1 - 0.15 11.3 0.1 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Carbpep_Y_N PF05388.11 KKA03614.1 - 0.064 13.8 0.4 0.32 11.5 0.1 2.4 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide tRNA_int_endo PF01974.17 KKA03615.1 - 4.9e-19 68.2 0.1 4e-18 65.3 0.0 2.4 3 0 0 3 3 3 1 tRNA intron endonuclease, catalytic C-terminal domain CDC45 PF02724.14 KKA03617.1 - 4.2e-157 524.2 3.2 5.2e-157 523.9 3.2 1.1 1 0 0 1 1 1 1 CDC45-like protein EarP PF10093.9 KKA03617.1 - 0.049 12.7 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP YL1 PF05764.13 KKA03617.1 - 0.13 12.4 1.9 0.21 11.7 1.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2624 PF11116.8 KKA03618.1 - 0.077 13.9 2.8 0.14 13.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2624) Zn_ribbon_17 PF17120.5 KKA03619.1 - 4.8e-11 42.1 17.7 1.2e-10 40.8 17.7 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KKA03619.1 - 7e-11 42.5 15.4 1.8e-06 28.6 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat EPSP_synthase PF00275.20 KKA03620.1 - 2.6e-136 454.7 0.0 3.9e-136 454.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KKA03620.1 - 3e-97 324.9 0.0 4.7e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KKA03620.1 - 2.1e-60 204.8 0.0 4.7e-60 203.7 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KKA03620.1 - 1.2e-28 100.3 0.0 9.4e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KKA03620.1 - 1.4e-21 76.6 0.0 4.3e-21 75.0 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KKA03620.1 - 2.1e-10 40.2 0.0 4.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KKA03620.1 - 7.6e-06 26.0 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 KKA03620.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_24 PF13479.6 KKA03620.1 - 0.00051 19.8 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKA03620.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKA03620.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 KKA03621.1 - 5.8e-26 91.2 10.3 5.8e-26 91.2 10.3 3.1 2 1 1 3 3 3 2 DHHC palmitoyltransferase DUF1201 PF06716.11 KKA03621.1 - 0.047 13.7 0.8 0.047 13.7 0.8 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1201) DUF4131 PF13567.6 KKA03621.1 - 0.99 9.0 3.9 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) F-box-like PF12937.7 KKA03622.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like Med25 PF11232.8 KKA03622.1 - 0.094 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 EB1 PF03271.17 KKA03622.1 - 0.21 11.9 0.3 0.21 11.9 0.3 2.7 3 0 0 3 3 3 0 EB1-like C-terminal motif HLH PF00010.26 KKA03623.1 - 1.7e-06 27.9 6.4 1.2e-05 25.2 1.6 3.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain End3 PF12761.7 KKA03623.1 - 0.012 15.7 8.2 0.027 14.6 8.2 1.6 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Mt_ATP_synt PF15704.5 KKA03623.1 - 0.19 11.6 5.1 0.18 11.6 2.5 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase subunit 3-PAP PF12578.8 KKA03623.1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.8 3 0 0 3 3 3 0 Myotubularin-associated protein Pkinase PF00069.25 KKA03624.1 - 5.1e-66 222.7 1.0 9.8e-64 215.2 1.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03624.1 - 9.5e-36 123.4 0.1 1.7e-34 119.3 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KKA03624.1 - 1.4e-11 44.0 0.0 3.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KKA03624.1 - 3.9e-07 29.7 0.0 6.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.11 KKA03624.1 - 7.6e-06 25.7 0.7 7.6e-06 25.7 0.7 1.8 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KKA03624.1 - 8e-06 25.4 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKA03624.1 - 0.0016 17.4 0.1 0.0016 17.4 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain pXO2-72 PF17443.2 KKA03624.1 - 0.027 14.7 0.1 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 APH PF01636.23 KKA03624.1 - 0.037 13.9 0.0 0.16 11.9 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKA03624.1 - 0.052 12.3 0.0 0.052 12.3 0.0 3.1 4 0 0 4 4 4 0 Fungal protein kinase RIO1 PF01163.22 KKA03624.1 - 0.063 12.9 0.1 0.24 11.0 0.1 2.0 1 0 0 1 1 1 0 RIO1 family PHD PF00628.29 KKA03625.1 - 0.0033 17.3 0.2 0.011 15.6 0.2 1.8 1 0 0 1 1 1 1 PHD-finger Alba PF01918.21 KKA03625.1 - 0.01 15.6 0.1 0.037 13.8 0.0 2.0 2 0 0 2 2 2 0 Alba DUF3364 PF11844.8 KKA03625.1 - 3.6 7.9 11.0 0.59 10.4 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3364) FMO-like PF00743.19 KKA03626.1 - 1.7e-35 122.4 2.9 2.7e-18 65.7 0.5 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKA03626.1 - 2.6e-12 46.7 6.1 4.8e-08 32.6 3.2 4.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKA03626.1 - 1.8e-11 43.8 0.0 5e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKA03626.1 - 5.5e-11 42.2 0.1 2.5e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKA03626.1 - 0.00014 21.2 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KKA03626.1 - 0.0025 18.0 0.0 0.0083 16.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KKA03626.1 - 0.019 15.0 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KKA03626.1 - 0.041 13.9 0.1 0.81 9.7 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding CoA_binding PF02629.19 KKA03626.1 - 0.13 13.0 0.1 2.7 8.7 0.0 2.5 3 0 0 3 3 3 0 CoA binding domain Pyr_redox PF00070.27 KKA03626.1 - 0.13 12.8 0.0 36 5.0 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CBFD_NFYB_HMF PF00808.23 KKA03627.1 - 3.2e-07 30.5 0.1 4.7e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNase_T PF00929.24 KKA03628.1 - 1.8e-27 96.9 0.2 3.1e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 Exonuclease DUF1149 PF06619.11 KKA03628.1 - 0.54 10.5 5.0 1.3 9.3 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) TRM PF02005.16 KKA03629.1 - 2.5e-117 392.2 0.0 3.4e-117 391.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KKA03629.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein adh_short PF00106.25 KKA03630.1 - 2.3e-34 118.5 0.0 3.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKA03630.1 - 1.3e-20 73.9 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KKA03630.1 - 2.7e-05 23.5 0.0 3.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KKA03630.1 - 0.00044 20.2 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KKA03630.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KKA03630.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Pkinase PF00069.25 KKA03631.1 - 1.9e-70 237.2 0.0 1.8e-67 227.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03631.1 - 3.3e-29 102.0 0.0 4.5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKA03631.1 - 2.7e-05 23.7 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKA03631.1 - 0.0024 16.9 0.1 0.049 12.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KKA03631.1 - 0.0028 16.8 0.2 0.0053 15.9 0.2 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KKA03631.1 - 0.012 15.6 0.1 0.057 13.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KKA03631.1 - 0.1 12.0 0.2 0.2 11.0 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_P_pop3 PF08228.11 KKA03632.1 - 4.2e-10 39.9 0.1 5.1e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 TruB_N PF01509.18 KKA03633.1 - 8.9e-28 97.5 0.3 1.7e-26 93.4 0.0 2.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KKA03633.1 - 4.3e-06 26.8 0.0 1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain ChlamPMP_M PF07548.11 KKA03633.1 - 0.0062 16.5 0.3 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 Chlamydia polymorphic membrane protein middle domain FliT PF05400.13 KKA03633.1 - 0.29 12.0 1.9 10 7.0 0.3 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Gly_transf_sug PF04488.15 KKA03634.1 - 2.8e-19 69.6 0.3 8e-19 68.1 0.3 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KKA03634.1 - 1.4 8.2 5.2 0.3 10.3 0.2 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain UCH PF00443.29 KKA03635.1 - 1.5e-15 57.4 0.0 3.1e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKA03635.1 - 0.0058 16.3 4.9 0.048 13.2 4.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ephrin_rec_like PF07699.13 KKA03635.1 - 7 6.5 7.9 0.77 9.6 1.7 2.2 2 0 0 2 2 2 0 Putative ephrin-receptor like PX PF00787.24 KKA03636.1 - 5.2e-13 49.0 0.2 1.5e-12 47.5 0.2 1.8 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KKA03636.1 - 1.3e-11 43.9 0.0 2.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKA03636.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 KKA03636.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain GPI-anchored PF10342.9 KKA03636.1 - 0.19 12.5 8.8 0.26 12.1 4.4 3.0 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DivIC PF04977.15 KKA03636.1 - 1.5 8.6 5.1 6.8 6.5 2.2 2.9 2 0 0 2 2 2 0 Septum formation initiator FAM193_C PF15914.5 KKA03637.1 - 0.37 10.6 0.1 0.37 10.6 0.1 2.4 3 0 0 3 3 3 0 FAM193 family C-terminal polyprenyl_synt PF00348.17 KKA03638.1 - 9.2e-43 146.1 0.1 1.2e-42 145.7 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Acid_PPase PF12689.7 KKA03638.1 - 0.079 12.8 0.2 4.6 7.1 0.0 2.9 2 1 1 3 3 3 0 Acid Phosphatase Peptidase_M24 PF00557.24 KKA03639.1 - 3.6e-50 170.6 0.2 4.4e-50 170.3 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KKA03639.1 - 1.9e-14 53.7 11.0 1.9e-14 53.7 11.0 2.5 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding dCMP_cyt_deam_1 PF00383.23 KKA03640.1 - 2.5e-10 40.1 0.0 3.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KKA03640.1 - 9.3e-05 22.1 0.2 0.0075 15.9 0.0 2.1 1 1 0 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.12 KKA03640.1 - 0.00075 19.7 1.4 0.077 13.2 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region ATP_bind_1 PF03029.17 KKA03641.1 - 1.5e-79 267.2 0.0 1.7e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KKA03641.1 - 3.2e-06 27.1 0.0 8.7e-05 22.4 0.0 2.4 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 KKA03641.1 - 0.00011 21.7 0.0 0.00068 19.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KKA03641.1 - 0.00013 22.5 0.0 0.00025 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KKA03641.1 - 0.00025 21.0 0.2 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 KKA03641.1 - 0.00033 21.0 0.1 0.0065 16.8 0.0 2.9 3 0 0 3 3 3 1 RNA helicase SRP54 PF00448.22 KKA03641.1 - 0.0012 18.6 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KKA03641.1 - 0.0013 19.2 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKA03641.1 - 0.0019 18.6 0.0 0.0078 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 KKA03641.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.5 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKA03641.1 - 0.0031 17.6 0.0 0.018 15.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKA03641.1 - 0.0039 17.5 0.0 0.0082 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KKA03641.1 - 0.0053 16.0 0.0 0.0084 15.3 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_24 PF13479.6 KKA03641.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KKA03641.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKA03641.1 - 0.0088 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 KKA03641.1 - 0.0098 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.27 KKA03641.1 - 0.0099 15.4 0.0 0.42 10.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TCTP PF00838.17 KKA03641.1 - 0.01 16.2 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein AAA_19 PF13245.6 KKA03641.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain MeaB PF03308.16 KKA03641.1 - 0.025 13.6 0.0 0.062 12.3 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KKA03641.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KKA03641.1 - 0.03 13.9 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 KKA03641.1 - 0.035 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KKA03641.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KKA03641.1 - 0.057 13.5 0.0 0.071 13.2 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KKA03641.1 - 0.061 12.5 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KKA03641.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KKA03641.1 - 0.065 12.5 0.0 0.072 12.3 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 KKA03641.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 KKA03641.1 - 0.067 12.9 0.0 0.89 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.17 KKA03641.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Roc PF08477.13 KKA03641.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 KKA03641.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_31 PF13614.6 KKA03641.1 - 0.095 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 KKA03641.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KKA03641.1 - 0.11 12.4 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KKA03641.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 KKA03641.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 ABC_tran PF00005.27 KKA03641.1 - 0.18 12.3 0.0 0.46 11.0 0.0 1.7 2 0 0 2 2 1 0 ABC transporter RecA PF00154.21 KKA03641.1 - 0.2 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein FeoB_N PF02421.18 KKA03641.1 - 0.68 9.5 2.5 14 5.2 0.1 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B zf-CCCH_4 PF18044.1 KKA03642.1 - 1.3e-09 37.6 3.2 2.9e-09 36.5 3.2 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KKA03642.1 - 6.8e-08 32.3 5.9 1.4e-07 31.3 5.9 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KKA03642.1 - 1.1e-06 29.2 0.1 3.1e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 KKA03642.1 - 1.9e-06 27.6 2.3 3.5e-06 26.8 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Birna_VP4 PF01768.16 KKA03642.1 - 0.058 13.2 0.9 12 5.6 0.0 2.6 1 1 1 3 3 3 0 Birnavirus VP4 protein zf-CCCH_2 PF14608.6 KKA03642.1 - 0.26 11.8 3.5 0.53 10.8 3.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 KKA03642.1 - 1.7 9.6 125.7 1.8e+04 -3.8 0.2 5.1 2 1 1 3 3 3 0 Nucleoporin FG repeat region Arv1 PF04161.13 KKA03643.1 - 9e-36 124.0 17.9 9e-36 124.0 17.9 2.0 2 0 0 2 2 2 1 Arv1-like family zf-ribbon_3 PF13248.6 KKA03643.1 - 0.016 14.6 0.6 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.17 KKA03643.1 - 0.048 13.6 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_2 PF13240.6 KKA03643.1 - 0.2 11.4 2.6 5.2 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain LIM PF00412.22 KKA03643.1 - 4.1 7.7 6.3 0.25 11.6 0.6 1.9 2 0 0 2 2 2 0 LIM domain RSN1_7TM PF02714.15 KKA03644.1 - 1.3e-70 237.9 33.5 1.3e-70 237.9 33.5 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKA03644.1 - 7.1e-33 113.6 6.3 7.1e-33 113.6 6.3 2.4 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKA03644.1 - 2.7e-20 73.3 0.2 2.2e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PI3_PI4_kinase PF00454.27 KKA03645.1 - 3.1e-34 118.9 0.0 2.8e-21 76.5 0.0 2.9 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KKA03645.1 - 4.2e-09 36.1 2.1 5.2e-09 35.8 0.5 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Big_5 PF13205.6 KKA03645.1 - 0.11 13.2 0.2 0.56 10.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain DUF4637 PF15470.6 KKA03646.1 - 0.15 11.8 5.5 0.99 9.1 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CoaE PF01121.20 KKA03647.1 - 3.1e-38 131.2 0.1 5.4e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KKA03647.1 - 0.0094 16.5 2.5 0.015 15.8 1.2 2.2 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.20 KKA03647.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.23 KKA03647.1 - 0.17 11.9 0.4 0.31 11.1 0.4 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KKA03647.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF5085 PF16895.5 KKA03648.1 - 0.044 14.1 2.7 2.9 8.2 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5085) DUF1906 PF08924.11 KKA03648.1 - 0.21 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) PilN PF05137.13 KKA03648.1 - 0.23 11.6 2.5 25 5.1 0.0 3.4 4 0 0 4 4 4 0 Fimbrial assembly protein (PilN) BPL_LplA_LipB PF03099.19 KKA03649.1 - 1.5e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Sushi_2 PF09014.10 KKA03649.1 - 0.059 13.3 0.5 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain FHA PF00498.26 KKA03650.1 - 1.4e-13 50.9 3.1 1.6e-13 50.8 0.2 2.7 2 1 2 4 4 4 1 FHA domain Yop-YscD_cpl PF16697.5 KKA03650.1 - 2.2e-06 27.9 0.1 8e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Noelin-1 PF12308.8 KKA03650.1 - 1.5 8.8 5.4 1.9 8.5 2.6 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein XhlA PF10779.9 KKA03650.1 - 2.4 8.4 10.4 0.34 11.1 0.5 3.1 1 1 1 3 3 3 0 Haemolysin XhlA KxDL PF10241.9 KKA03650.1 - 4.2 7.7 13.2 2.5 8.5 3.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein DASH_Dad4 PF08650.10 KKA03650.1 - 9.3 6.3 14.8 1.9 8.5 2.7 3.5 2 2 2 4 4 4 0 DASH complex subunit Dad4 Rogdi_lz PF10259.9 KKA03651.1 - 0.00014 21.4 0.4 0.13 11.6 0.2 2.5 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein eIF3_N PF09440.10 KKA03651.1 - 0.0044 17.4 0.1 0.0091 16.4 0.1 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain MtrG PF04210.13 KKA03651.1 - 0.14 12.0 1.0 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Coq4 PF05019.13 KKA03652.1 - 3e-41 141.2 0.0 4.2e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Cation_efflux PF01545.21 KKA03653.1 - 7.5e-30 104.2 13.8 6.8e-29 101.0 13.8 2.0 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.16 KKA03653.1 - 0.0068 15.8 5.6 0.0068 15.8 5.6 2.0 1 1 1 2 2 2 1 High-affinity nickel-transport protein UPF0242 PF06785.11 KKA03653.1 - 0.024 14.8 0.5 0.024 14.8 0.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4834 PF16118.5 KKA03653.1 - 0.23 12.5 0.1 0.23 12.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) PDE4_UCR PF18100.1 KKA03653.1 - 0.28 11.8 2.3 0.54 10.9 2.3 1.4 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) MMM1 PF10296.9 KKA03653.1 - 0.39 9.7 5.1 0.089 11.8 0.9 2.0 2 1 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Topoisom_bac PF01131.20 KKA03654.1 - 2.6e-87 293.5 0.0 3.3e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KKA03654.1 - 1.1e-16 60.9 0.0 2.8e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Toprim domain PIP5K PF01504.18 KKA03655.1 - 3.6e-79 265.8 1.2 1.3e-77 260.8 1.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PD40 PF07676.12 KKA03655.1 - 0.42 10.6 1.9 11 6.1 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.18 KKA03657.1 - 1.2e-08 35.0 11.5 2.5e-08 33.9 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1 PF10374.9 KKA03658.1 - 6.9e-06 26.7 5.8 6.9e-06 26.7 5.8 3.7 3 3 0 3 3 3 1 Telomerase activating protein Est1 IQCJ-SCHIP1 PF15157.6 KKA03658.1 - 1.8 8.4 9.8 2.4 8.0 4.0 3.1 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif W2 PF02020.18 KKA03659.1 - 2.2e-10 40.5 2.7 2.2e-10 40.5 2.7 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KKA03659.1 - 8.2e-09 34.9 14.9 6e-06 25.8 5.0 4.1 1 1 4 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KKA03659.1 - 1.7e-06 27.2 1.2 3.3e-06 26.3 1.2 1.4 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 KKA03659.1 - 8.4e-06 25.5 0.0 3.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase AAA_21 PF13304.6 KKA03659.1 - 0.00091 19.1 0.4 0.0021 17.9 0.4 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Hexapep_2 PF14602.6 KKA03659.1 - 0.0022 17.7 9.7 0.077 12.8 9.7 2.7 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KKA03659.1 - 0.021 15.2 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Mis12 PF05859.12 KKA03659.1 - 0.16 12.0 1.4 0.61 10.1 0.1 2.3 2 0 0 2 2 2 0 Mis12 protein Ras PF00071.22 KKA03660.1 - 8.4e-51 171.8 0.0 9.7e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKA03660.1 - 1.3e-18 67.3 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKA03660.1 - 6.9e-07 28.9 0.0 8.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cpn60_TCP1 PF00118.24 KKA03661.1 - 3.3e-147 491.1 16.8 3.8e-147 490.9 16.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-synt_Eps PF04627.13 KKA03661.1 - 0.04 13.9 1.8 0.064 13.3 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Zn_clus PF00172.18 KKA03662.1 - 8e-09 35.5 14.4 1.4e-08 34.7 14.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFP_35_N PF07334.13 KKA03662.1 - 2.3 8.3 6.8 5.8 7.1 0.3 3.8 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Aha1_N PF09229.11 KKA03663.1 - 3.6e-33 114.7 1.6 3.6e-33 114.7 1.6 2.2 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KKA03663.1 - 7.7e-07 29.4 0.0 2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Hydrolase_6 PF13344.6 KKA03664.1 - 2.1e-18 66.3 0.0 4.8e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKA03664.1 - 3e-10 40.0 0.0 8.2e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like BRCT PF00533.26 KKA03665.1 - 0.00073 19.9 1.0 0.0023 18.3 0.3 2.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad9_Rad53_bind PF08605.10 KKA03665.1 - 0.003 17.8 0.5 0.0084 16.3 0.5 1.8 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT_2 PF16589.5 KKA03665.1 - 0.0046 17.3 0.1 0.016 15.6 0.1 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Septin PF00735.18 KKA03666.1 - 1.2e-65 221.7 1.3 1.2e-65 221.7 1.3 2.6 2 1 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KKA03666.1 - 0.0016 18.3 0.1 0.27 11.1 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 KKA03666.1 - 0.015 15.8 0.0 0.043 14.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 KKA03666.1 - 0.28 11.2 1.9 0.65 10.0 0.0 2.5 3 1 0 3 3 3 0 Dynamin family RBFA PF02033.18 KKA03667.1 - 0.059 13.8 0.1 0.18 12.3 0.1 1.8 1 0 0 1 1 1 0 Ribosome-binding factor A Utp13 PF08625.11 KKA03668.1 - 2.2e-45 154.1 0.9 5.3e-45 152.8 0.9 1.7 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KKA03668.1 - 1e-40 137.0 15.5 1.9e-07 31.7 0.2 9.9 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03668.1 - 1.8e-09 37.8 5.6 0.054 13.8 0.0 7.0 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKA03668.1 - 1.1e-06 28.3 6.6 0.014 14.8 0.0 3.8 2 2 2 4 4 4 2 WD40-like domain BBS2_Mid PF14783.6 KKA03668.1 - 0.0061 16.6 0.2 0.21 11.6 0.0 3.4 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region UTP15_C PF09384.10 KKA03668.1 - 0.048 13.3 0.1 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 UTP15 C terminal Nbas_N PF15492.6 KKA03668.1 - 0.066 12.5 0.1 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal VIT1 PF01988.19 KKA03669.1 - 1e-61 208.5 0.1 1.3e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 VIT family DUF2207 PF09972.9 KKA03669.1 - 0.018 13.8 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PsbI PF02532.14 KKA03669.1 - 0.088 12.8 1.8 0.17 11.8 1.8 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) ADK PF00406.22 KKA03671.1 - 1.9e-59 200.1 0.0 2.2e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKA03671.1 - 3.7e-24 85.7 0.1 1.3e-23 83.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KKA03671.1 - 3.3e-16 59.0 0.0 8.1e-16 57.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KKA03671.1 - 3.3e-06 27.3 0.0 9.1e-06 25.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKA03671.1 - 5.9e-05 23.6 0.0 0.00024 21.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KKA03671.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Thymidylate_kin PF02223.17 KKA03671.1 - 0.06 13.0 0.1 0.22 11.2 0.0 1.9 3 0 0 3 3 3 0 Thymidylate kinase 14-3-3 PF00244.20 KKA03671.1 - 0.16 11.5 0.2 0.72 9.3 0.2 1.9 1 1 0 1 1 1 0 14-3-3 protein CRF1 PF10380.9 KKA03673.1 - 1.6e-08 34.9 4.3 1.6e-08 34.9 4.3 5.6 4 3 1 5 5 5 1 Transcription factor CRF1 PRKCSH_1 PF13015.6 KKA03674.1 - 2.4e-15 56.6 9.4 1.5e-14 53.9 9.4 2.2 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KKA03674.1 - 0.002 18.1 0.2 0.0029 17.5 0.2 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 PRKCSH PF07915.13 KKA03674.1 - 0.015 16.3 2.0 0.02 15.9 0.3 2.0 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein DUF29 PF01724.16 KKA03674.1 - 0.016 15.4 0.5 0.016 15.4 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 Hypoth_Ymh PF09509.10 KKA03674.1 - 0.076 12.9 0.3 3 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) Scm3 PF10384.9 KKA03674.1 - 0.079 12.7 5.5 0.23 11.2 0.5 3.1 3 0 0 3 3 3 0 Centromere protein Scm3 RecG_N PF17190.4 KKA03674.1 - 0.14 12.9 8.0 3.2 8.5 1.4 2.6 2 1 1 3 3 3 0 RecG N-terminal helical domain RE_ApaLI PF09499.10 KKA03674.1 - 0.15 11.7 5.5 0.12 12.1 1.1 2.1 1 1 1 2 2 2 0 ApaLI-like restriction endonuclease Fib_alpha PF08702.10 KKA03674.1 - 4.8 7.4 7.9 1.5 9.0 2.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rgp1 PF08737.10 KKA03675.1 - 0.044 13.0 5.9 0.048 12.8 5.9 1.0 1 0 0 1 1 1 0 Rgp1 PGI PF00342.19 KKA03676.1 - 6.7e-225 747.2 1.2 7.7e-225 747.0 1.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase GPI2 PF06432.11 KKA03677.1 - 1.3e-16 60.9 29.8 2.7e-16 59.9 29.8 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase WD40 PF00400.32 KKA03678.1 - 5.2e-36 122.0 16.4 4.5e-07 30.5 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KKA03678.1 - 2.3e-13 50.5 10.0 9.6e-11 42.0 10.0 2.5 1 1 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KKA03678.1 - 1.8e-10 41.0 0.1 0.022 15.0 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKA03678.1 - 2.5e-05 23.2 1.6 0.006 15.3 0.1 3.6 2 1 2 4 4 4 1 Nucleoporin Nup120/160 LisH PF08513.11 KKA03678.1 - 0.003 17.5 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 LisH SSXRD PF09514.10 KKA03678.1 - 0.18 11.4 1.5 0.4 10.3 1.5 1.6 1 0 0 1 1 1 0 SSXRD motif GCR1_C PF12550.8 KKA03679.1 - 8.8e-12 45.2 8.6 7.4e-09 35.8 2.2 3.7 4 0 0 4 4 4 2 Transcriptional activator of glycolytic enzymes NHL PF01436.21 KKA03679.1 - 0.24 11.5 0.7 11 6.2 0.2 2.7 2 0 0 2 2 2 0 NHL repeat TEX13 PF15186.6 KKA03679.1 - 2.7 7.7 6.5 1.4 8.6 2.8 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family ALIX_LYPXL_bnd PF13949.6 KKA03682.1 - 2.9e-07 30.1 7.9 3.9e-07 29.7 7.9 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 KKA03683.1 - 4.8e-19 68.4 13.5 1.8e-17 63.2 13.5 2.3 1 1 0 1 1 1 1 BRO1-like domain Bromodomain PF00439.25 KKA03683.1 - 0.12 12.4 3.4 4.5 7.4 0.2 3.4 3 0 0 3 3 3 0 Bromodomain MBA1 PF07961.11 KKA03684.1 - 7.9e-24 84.0 7.1 1.2e-23 83.5 7.1 1.3 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KKA03684.1 - 0.012 15.7 0.3 0.034 14.3 0.3 1.7 1 1 0 1 1 1 0 Tim44-like domain Sec16_C PF12931.7 KKA03685.1 - 1.5e-55 189.0 0.1 3.6e-55 187.8 0.1 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KKA03685.1 - 6.8e-05 23.4 0.0 0.00087 19.9 0.0 3.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Radical_SAM_C PF16199.5 KKA03686.1 - 6.9e-31 106.1 0.0 1.4e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KKA03686.1 - 8.9e-19 68.5 0.7 2.8e-18 66.9 0.1 2.1 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KKA03686.1 - 1.5e-11 44.6 0.1 2.7e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKA03686.1 - 1.8e-06 27.9 0.0 6e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKA03686.1 - 0.027 14.9 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Porphobil_deam PF01379.20 KKA03687.1 - 1.7e-71 239.9 0.0 2.6e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KKA03687.1 - 2.4e-18 66.2 0.3 4.1e-18 65.5 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ceramidase PF05875.12 KKA03688.1 - 2e-75 253.6 7.7 2.7e-75 253.2 7.7 1.2 1 0 0 1 1 1 1 Ceramidase Pyr_redox_2 PF07992.14 KKA03689.1 - 2.4e-63 214.1 1.5 5e-63 213.1 1.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKA03689.1 - 6.1e-33 113.4 0.6 2.5e-32 111.4 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKA03689.1 - 1e-19 70.8 7.2 2.5e-18 66.4 1.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKA03689.1 - 1.3e-14 54.1 5.4 1.9e-13 50.3 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKA03689.1 - 8.6e-09 35.2 0.1 7.8e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KKA03689.1 - 3.6e-07 29.7 0.2 1.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KKA03689.1 - 7.9e-06 24.8 5.1 0.13 10.9 0.6 3.3 2 1 0 3 3 3 3 HI0933-like protein GIDA PF01134.22 KKA03689.1 - 0.0019 17.4 3.2 0.0019 17.4 3.2 2.8 2 2 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KKA03689.1 - 0.0022 17.3 1.4 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KKA03689.1 - 0.01 16.2 0.1 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KKA03689.1 - 0.012 15.0 0.7 1.8 7.9 0.0 3.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KKA03689.1 - 0.047 12.8 4.8 0.094 11.8 1.9 2.6 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 KKA03689.1 - 0.076 12.9 2.1 0.25 11.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2854 PF11016.8 KKA03689.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) NAD_binding_8 PF13450.6 KKA03689.1 - 0.73 10.1 3.9 2 8.7 3.9 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NOG1_N PF17835.1 KKA03690.1 - 9.1e-50 168.7 0.5 9.1e-50 168.7 0.5 2.7 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KKA03690.1 - 7.3e-27 93.1 5.2 7.3e-27 93.1 5.2 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 KKA03690.1 - 3.2e-26 90.9 0.2 8.5e-26 89.5 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KKA03690.1 - 5.8e-17 61.8 0.0 1.5e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKA03690.1 - 3.2e-09 36.5 0.1 8.4e-09 35.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKA03690.1 - 0.0025 17.9 3.5 0.77 9.8 0.0 3.6 2 2 1 3 3 3 2 Dynamin family Roc PF08477.13 KKA03690.1 - 0.0033 17.6 0.0 0.0094 16.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KKA03690.1 - 0.0063 16.4 0.3 3.6 7.5 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase Sec62 PF03839.16 KKA03691.1 - 1.8e-47 161.6 8.4 6e-44 150.1 4.7 2.2 2 0 0 2 2 2 2 Translocation protein Sec62 Dynamin_N PF00350.23 KKA03692.1 - 1.4e-11 44.7 4.1 1.6e-11 44.5 1.6 2.5 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 KKA03692.1 - 2.4e-08 33.7 0.3 3.9e-05 23.3 0.4 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKA03692.1 - 3.6e-08 33.5 0.3 1.9e-07 31.2 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KKA03692.1 - 0.011 15.3 2.7 0.097 12.3 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KKA03692.1 - 0.016 15.2 0.1 0.069 13.2 0.0 2.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KKA03692.1 - 0.026 13.6 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NAD_Gly3P_dh_N PF01210.23 KKA03692.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Roc PF08477.13 KKA03692.1 - 0.059 13.6 0.1 0.54 10.5 0.0 2.5 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Abhydrolase_1 PF00561.20 KKA03693.1 - 1.4e-22 80.6 0.0 2.1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA03693.1 - 6.1e-10 38.8 0.0 1.3e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KKA03693.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.7 1 1 0 1 1 1 0 Palmitoyl protein thioesterase DUF1344 PF07076.11 KKA03693.1 - 0.049 13.5 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Cutinase PF01083.22 KKA03693.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.12 KKA03693.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CAMSAP_CH PF11971.8 KKA03694.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain DUF624 PF04854.14 KKA03694.1 - 0.12 12.5 3.2 1.3 9.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 ANAPC4_WD40 PF12894.7 KKA03695.1 - 0.0033 17.7 0.1 14 6.1 0.0 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain LAMTOR PF15454.6 KKA03695.1 - 0.086 13.5 0.1 0.086 13.5 0.1 2.2 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PAXNEB PF05625.11 KKA03696.1 - 2.1e-37 129.1 0.9 3.2e-37 128.5 0.9 1.2 1 0 0 1 1 1 1 PAXNEB protein Dynamin_M PF01031.20 KKA03696.1 - 0.015 14.5 0.3 0.027 13.7 0.3 1.4 1 0 0 1 1 1 0 Dynamin central region Abhydrolase_6 PF12697.7 KKA03697.1 - 1.8e-10 41.8 0.0 2.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKA03697.1 - 2e-10 40.7 0.0 5.9e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKA03697.1 - 4.3e-08 32.7 0.0 6.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KKA03697.1 - 2.9e-05 23.8 0.0 0.00012 21.8 0.0 2.0 1 1 0 2 2 2 1 Putative esterase DUF676 PF05057.14 KKA03697.1 - 0.0035 16.9 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 KKA03697.1 - 0.018 15.2 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain tRNA-synt_2 PF00152.20 KKA03698.1 - 7.7e-86 288.0 0.6 1.1e-85 287.5 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKA03698.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 KKA03698.1 - 0.064 13.2 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 KKA03698.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) WD40 PF00400.32 KKA03699.1 - 3.3e-20 72.0 5.1 0.0012 19.6 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03699.1 - 8.2e-17 61.3 0.5 0.011 16.0 0.0 5.1 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKA03699.1 - 8.3e-05 21.7 1.3 3.8 6.4 0.0 4.3 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKA03699.1 - 0.00026 19.8 0.3 1.6 7.3 0.0 3.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 UMP1 PF05348.11 KKA03700.1 - 6.3e-21 74.8 0.5 8.8e-21 74.3 0.5 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 EKAL PF17986.1 KKA03700.1 - 0.3 11.1 2.5 4.1 7.5 0.1 2.3 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain GYF PF02213.16 KKA03701.1 - 2e-12 46.6 0.0 5.1e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 GYF domain Forkhead_N PF08430.12 KKA03701.1 - 5 7.8 31.3 3 8.5 21.2 2.7 2 0 0 2 2 2 0 Forkhead N-terminal region Sec66 PF09802.9 KKA03702.1 - 1.5e-35 122.4 1.4 1.7e-35 122.3 1.4 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Pentapeptide_3 PF13576.6 KKA03702.1 - 0.12 12.5 7.7 0.26 11.5 7.7 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Mito_carr PF00153.27 KKA03703.1 - 0.00035 20.4 0.2 0.68 9.9 0.0 3.8 3 1 1 4 4 4 2 Mitochondrial carrier protein DUF1091 PF06477.13 KKA03703.1 - 0.033 14.7 5.1 0.19 12.2 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) NPL4 PF05021.15 KKA03704.1 - 1.4e-108 362.9 0.0 2e-108 362.4 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KKA03704.1 - 9e-57 191.3 1.5 1.8e-56 190.3 1.5 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region E6 PF00518.17 KKA03704.1 - 0.075 13.5 0.2 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Early Protein (E6) HSP70 PF00012.20 KKA03705.1 - 3.5e-139 464.7 15.4 3.5e-139 464.7 15.4 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KKA03705.1 - 8.6e-09 34.6 0.1 1.6e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein EAP30 PF04157.16 KKA03705.1 - 7.5 5.8 8.7 32 3.7 5.0 2.8 3 0 0 3 3 3 0 EAP30/Vps36 family Oxidored-like PF09791.9 KKA03706.1 - 2.2e-08 33.6 0.7 3.6e-08 32.9 0.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Ureidogly_lyase PF04115.12 KKA03707.1 - 6.4e-39 133.7 0.0 7.3e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase CDH PF02611.15 KKA03707.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Rpp20 PF12328.8 KKA03708.1 - 0.0002 21.4 6.2 0.0021 18.0 6.2 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KKA03708.1 - 0.00062 19.5 0.8 0.0014 18.4 0.8 1.6 1 0 0 1 1 1 1 Alba NAD_binding_2 PF03446.15 KKA03709.1 - 1.1e-05 25.6 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KKA03709.1 - 0.00023 20.6 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKA03709.1 - 0.00038 20.1 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KKA03709.1 - 0.00055 19.9 0.0 0.00077 19.5 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KKA03709.1 - 0.00068 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pullulanase_Ins PF18494.1 KKA03709.1 - 0.00076 19.9 0.4 0.0021 18.5 0.1 1.8 2 0 0 2 2 2 1 Pullulanase Ins domain 3HCDH_N PF02737.18 KKA03709.1 - 0.0019 18.1 0.1 0.0029 17.5 0.1 1.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKA03709.1 - 0.0033 17.5 0.1 0.005 16.9 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KKA03709.1 - 0.0097 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Gp_dh_N PF00044.24 KKA03709.1 - 0.026 14.8 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PDH PF02153.17 KKA03710.1 - 1.1e-05 24.5 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Ribosomal_L18_c PF14204.6 KKA03710.1 - 3.7 8.6 6.1 4.8 8.2 2.1 2.4 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region tRNA-synt_1b PF00579.25 KKA03711.1 - 6.9e-60 202.8 0.6 1.1e-59 202.2 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KKA03711.1 - 0.0015 18.3 0.2 0.085 12.7 0.1 3.3 4 0 0 4 4 4 1 Tyrosyl-tRNA synthetase C-terminal domain RL PF17797.1 KKA03711.1 - 0.031 14.2 0.8 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 RL domain Sa_NUDIX PF18167.1 KKA03712.1 - 0.025 14.4 2.0 0.054 13.3 2.0 1.5 1 0 0 1 1 1 0 SMODS-associated NUDIX domain MALT1_Ig PF18703.1 KKA03713.1 - 0.71 9.9 5.4 11 6.1 0.1 3.2 2 1 1 3 3 3 0 MALT1 Ig-like domain Ribosomal_L7Ae PF01248.26 KKA03714.1 - 1.7e-22 79.0 0.1 3.3e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 KKA03714.1 - 0.029 14.3 1.6 0.051 13.5 1.6 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TP_methylase PF00590.20 KKA03714.1 - 0.17 11.8 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Transp_cyt_pur PF02133.15 KKA03715.1 - 1e-17 64.1 32.6 1e-17 64.1 32.6 1.5 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.18 KKA03715.1 - 0.0034 16.4 1.6 0.0034 16.4 1.6 2.7 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein TPR_11 PF13414.6 KKA03717.1 - 1.2e-19 69.7 0.0 1.2e-08 34.5 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 KKA03717.1 - 2.1e-19 68.4 0.1 1.5e-07 30.9 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKA03717.1 - 1.2e-17 62.5 0.0 3.8e-06 26.6 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKA03717.1 - 1.5e-14 53.2 0.0 2.9e-05 24.1 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKA03717.1 - 2e-13 49.4 0.0 0.0038 17.3 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKA03717.1 - 2.3e-10 40.4 0.1 0.015 16.1 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKA03717.1 - 8.1e-10 39.2 0.0 6.5e-05 23.5 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKA03717.1 - 1.2e-08 35.3 0.0 0.038 14.5 0.0 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA03717.1 - 4.3e-06 26.9 0.1 0.035 14.3 0.0 3.3 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KKA03717.1 - 4.4e-06 26.4 0.1 0.39 10.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKA03717.1 - 4.2e-05 23.7 0.1 0.046 14.0 0.1 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKA03717.1 - 0.00052 19.8 0.5 0.048 13.5 0.2 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKA03717.1 - 0.0012 19.0 0.0 6.8 6.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KKA03717.1 - 0.0032 17.7 0.3 23 5.4 0.0 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KKA03717.1 - 0.0033 17.5 0.2 0.42 10.7 0.1 2.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KKA03717.1 - 0.0084 16.1 0.0 0.084 12.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKA03717.1 - 0.028 15.0 0.1 92 4.0 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KKA03717.1 - 0.039 13.4 0.3 11 5.6 0.0 4.1 4 0 0 4 4 4 0 SHNi-TPR ERCC4 PF02732.15 KKA03719.1 - 2.5e-14 53.8 0.0 2.5e-14 53.8 0.0 3.7 3 2 1 4 4 4 1 ERCC4 domain MTHFR PF02219.17 KKA03720.1 - 3.6e-88 295.6 0.7 3.6e-88 295.6 0.7 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase RMI1_N PF08585.12 KKA03721.1 - 2.1e-09 37.4 1.4 4.6e-09 36.4 1.4 1.6 1 1 0 1 1 1 1 RecQ mediated genome instability protein Sybindin PF04099.12 KKA03722.1 - 5.2e-28 97.8 2.8 3.4e-17 62.7 0.8 2.1 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 KKA03722.1 - 7.2e-08 32.6 0.9 7.2e-08 32.6 0.9 1.9 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region NAC PF01849.18 KKA03723.1 - 0.0024 17.8 0.1 0.012 15.6 0.0 2.3 2 1 0 2 2 2 1 NAC domain Toprim_2 PF13155.6 KKA03723.1 - 0.12 12.8 0.2 0.52 10.8 0.1 1.9 2 0 0 2 2 2 0 Toprim-like RHH_3 PF12651.7 KKA03723.1 - 0.19 11.7 1.8 15 5.7 0.1 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix domain CSN5_C PF18323.1 KKA03723.1 - 0.33 11.9 4.5 5.7 7.9 0.1 2.9 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain AdoMet_MTase PF07757.13 KKA03725.1 - 9.5e-36 122.5 0.6 1.9e-35 121.6 0.6 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF5484 PF17583.2 KKA03725.1 - 0.23 11.1 2.6 18 5.1 0.2 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5484) Thiolase_N PF00108.23 KKA03726.1 - 3.5e-92 308.5 0.2 4.2e-92 308.2 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKA03726.1 - 1.7e-42 143.9 0.6 4.4e-42 142.6 0.1 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKA03726.1 - 0.0062 16.1 0.2 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.25 KKA03727.1 - 1.5e-34 119.6 1.8 2.3e-27 96.0 0.7 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03727.1 - 9.1e-15 54.6 0.1 8.9e-11 41.6 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KKA03727.1 - 0.082 12.3 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF601 PF04642.12 KKA03727.1 - 0.11 12.0 3.5 0.16 11.4 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 APS_kinase PF01583.20 KKA03728.1 - 6.3e-05 22.9 0.0 8.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KKA03728.1 - 6.7e-05 23.4 0.1 0.00019 22.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KKA03728.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KKA03728.1 - 0.03 14.5 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKA03728.1 - 0.034 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KKA03728.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KKA03728.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ploopntkinase2 PF18747.1 KKA03728.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 AAA_30 PF13604.6 KKA03728.1 - 0.12 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKA03728.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKA03728.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain tRNA-synt_1 PF00133.22 KKA03729.1 - 1.3e-138 462.9 7.0 2e-138 462.3 7.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKA03729.1 - 8.9e-19 67.5 8.0 5.9e-08 31.9 2.7 4.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKA03729.1 - 3.5e-12 46.5 0.1 9.7e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA CENP-H PF05837.12 KKA03729.1 - 0.66 10.4 5.1 1.5 9.3 0.5 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Phage_XkdX PF09693.10 KKA03730.1 - 3.2 7.8 7.9 0.43 10.6 0.9 3.2 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) LIAS_N PF16881.5 KKA03732.1 - 1e-22 80.6 2.1 1.6e-22 79.9 0.6 2.0 2 1 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KKA03732.1 - 6.3e-15 55.9 0.0 1.3e-14 54.9 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Spore_GerAC PF05504.11 KKA03732.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal RhoGAP PF00620.27 KKA03733.1 - 2e-25 89.4 0.4 6.8e-25 87.7 0.4 2.0 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KKA03733.1 - 0.085 13.4 0.7 0.94 10.0 0.7 3.0 1 1 0 1 1 1 0 PH domain PEX11 PF05648.14 KKA03734.1 - 7.7e-13 48.4 4.6 2.4e-11 43.5 1.8 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) TFIIA PF03153.13 KKA03735.1 - 2e-38 133.5 34.1 9.8e-25 88.4 27.9 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DASH_Spc19 PF08287.11 KKA03735.1 - 0.0027 17.6 6.1 0.0045 16.9 6.1 1.3 1 0 0 1 1 1 1 Spc19 DUF4763 PF15960.5 KKA03735.1 - 0.15 11.3 8.4 0.19 11.0 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) AAA_11 PF13086.6 KKA03735.1 - 0.62 9.8 3.6 0.73 9.6 3.6 1.1 1 0 0 1 1 1 0 AAA domain Fungal_TACC PF12709.7 KKA03736.1 - 1.5e-06 28.5 12.8 1.5e-06 28.5 12.8 4.3 3 1 0 4 4 4 1 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 KKA03736.1 - 7.2 5.4 53.9 1.1 8.0 28.9 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Noc2 PF03715.13 KKA03737.1 - 9.9e-113 376.3 14.7 9.9e-113 376.3 14.7 1.9 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 KKA03737.1 - 1.6e-06 26.7 2.8 1.6e-06 26.7 2.8 3.3 2 1 1 3 3 3 1 Nop14-like family DUF1128 PF06569.11 KKA03737.1 - 5.6 7.0 13.4 19 5.3 0.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1128) ABC2_membrane PF01061.24 KKA03738.1 - 8.7e-65 218.1 55.5 1.3e-35 122.8 16.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKA03738.1 - 5.8e-36 124.0 2.4 2.5e-17 63.6 0.1 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KKA03738.1 - 1.7e-27 95.1 4.7 3.4e-22 78.1 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KKA03738.1 - 2.9e-09 37.4 0.1 1.3e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKA03738.1 - 6.4e-05 23.4 0.2 0.011 16.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKA03738.1 - 0.00089 19.2 0.1 0.026 14.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KKA03738.1 - 0.004 16.6 0.0 5.7 6.3 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKA03738.1 - 0.0055 17.0 0.0 0.64 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKA03738.1 - 0.007 16.2 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KKA03738.1 - 0.0099 15.5 0.0 0.063 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KKA03738.1 - 0.017 14.4 0.2 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 KKA03738.1 - 0.02 15.0 0.2 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KKA03738.1 - 0.026 14.3 1.0 0.53 10.1 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KKA03738.1 - 0.026 14.9 0.0 17 5.9 0.0 3.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKA03738.1 - 0.028 14.2 0.1 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKA03738.1 - 0.085 13.4 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DnaT PF17948.1 KKA03738.1 - 0.11 12.2 0.4 0.94 9.2 0.0 2.7 2 0 0 2 2 2 0 DnaT DNA-binding domain AAA_28 PF13521.6 KKA03738.1 - 0.14 12.4 0.1 2.2 8.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF3535 PF12054.8 KKA03739.1 - 3.2e-77 260.6 0.1 1.3e-73 248.8 0.2 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KKA03739.1 - 1.3e-64 218.2 0.0 3.6e-64 216.7 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA03739.1 - 3.3e-18 66.0 0.0 1.9e-17 63.6 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KKA03739.1 - 7.8e-10 38.2 2.4 2 8.9 0.0 7.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KKA03739.1 - 6.4e-08 32.9 0.8 0.0015 19.0 0.0 5.8 6 0 0 6 6 6 1 HEAT-like repeat TAF6_C PF07571.13 KKA03739.1 - 0.0016 18.7 1.2 3.2 8.1 0.0 5.4 5 1 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 KKA03739.1 - 0.017 15.5 0.0 3.6 8.0 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats ERCC3_RAD25_C PF16203.5 KKA03739.1 - 0.026 13.7 0.0 0.099 11.8 0.0 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase MazG_C PF18722.1 KKA03739.1 - 0.078 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 MazG C-terminal domain Mito_carr PF00153.27 KKA03740.1 - 9.3e-69 227.4 2.1 8e-26 89.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med8 PF10232.9 KKA03741.1 - 0.00011 21.8 1.3 0.00017 21.3 1.3 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Catalase PF00199.19 KKA03742.1 - 1.9e-114 382.7 0.4 2.5e-114 382.3 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KKA03742.1 - 7.2e-10 38.9 0.0 2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Baculo_VP91_N PF08475.10 KKA03743.1 - 0.016 14.9 0.4 0.025 14.3 0.4 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal CAF1C_H4-bd PF12265.8 KKA03744.1 - 1.9e-13 50.5 3.0 6.5e-13 48.7 3.0 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KKA03744.1 - 1.8e-10 41.2 11.9 0.03 15.2 1.6 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03744.1 - 4.6e-07 30.1 2.5 0.0034 17.6 0.1 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKA03744.1 - 0.00059 19.8 5.7 0.053 13.4 0.1 4.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Mito_carr PF00153.27 KKA03745.1 - 9.8e-35 118.4 2.4 3.6e-16 58.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_4 PF02390.17 KKA03746.1 - 2.5e-53 180.1 0.1 4.3e-53 179.3 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KKA03746.1 - 0.00035 20.1 0.0 0.014 14.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KKA03746.1 - 0.0006 19.6 0.3 0.0043 16.8 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKA03746.1 - 0.0023 18.6 0.0 0.0073 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKA03746.1 - 0.06 14.1 0.0 0.21 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KKA03746.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KKA03746.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 KKA03746.1 - 0.11 12.8 0.2 0.46 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) Sugar_tr PF00083.24 KKA03747.1 - 5.9e-84 282.5 24.7 7.2e-84 282.2 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKA03747.1 - 1.1e-21 77.2 23.9 4.2e-14 52.2 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KKA03747.1 - 0.32 11.3 2.5 0.37 11.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF459 PF04311.13 KKA03748.1 - 0.018 14.0 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) HGD-D PF06050.13 KKA03748.1 - 0.095 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DNA_methylase PF00145.17 KKA03748.1 - 0.16 11.3 1.9 0.21 10.9 0.3 1.8 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase CARD PF00619.21 KKA03748.1 - 0.17 12.0 2.2 17 5.6 0.0 3.0 2 1 0 3 3 3 0 Caspase recruitment domain Swm2 PF17083.5 KKA03749.1 - 0.0051 16.8 0.9 0.016 15.2 0.5 1.9 1 1 1 2 2 2 1 Nucleolar protein Swm2 PRESAN PF09687.10 KKA03749.1 - 0.036 14.6 2.5 0.066 13.8 2.5 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal COMMD1_N PF17221.3 KKA03749.1 - 0.1 12.9 1.7 0.19 12.0 1.4 1.6 1 1 0 1 1 1 0 COMMD1 N-terminal domain Glyco_hydro_38N PF01074.22 KKA03750.1 - 3e-67 227.0 0.1 5.8e-67 226.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KKA03750.1 - 1.4e-35 123.3 0.2 1.4e-35 123.3 0.2 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KKA03750.1 - 7.7e-22 77.3 0.1 2.2e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain DUF3767 PF12597.8 KKA03751.1 - 8.9e-23 80.0 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) SHOCT PF09851.9 KKA03751.1 - 8.4e-05 22.2 2.9 0.00048 19.8 2.6 2.4 2 0 0 2 2 2 1 Short C-terminal domain DUF3899 PF13038.6 KKA03751.1 - 0.17 12.4 0.3 0.17 12.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4574 PF15141.6 KKA03751.1 - 6 6.8 5.4 19 5.2 0.1 3.1 3 1 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Sel1 PF08238.12 KKA03752.1 - 4.1e-11 43.2 11.7 2.4e-05 24.8 0.2 5.6 6 0 0 6 6 6 4 Sel1 repeat Aminotran_1_2 PF00155.21 KKA03753.1 - 8.8e-72 242.3 0.1 1.2e-71 241.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKA03753.1 - 6.6e-09 34.8 0.0 1.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKA03753.1 - 1.2e-05 24.5 0.2 3.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKA03753.1 - 0.00024 20.5 0.1 0.00044 19.6 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.10 KKA03753.1 - 0.0017 18.8 0.4 0.0047 17.4 0.4 1.7 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence YobH PF13996.6 KKA03753.1 - 0.19 11.8 0.3 0.77 9.8 0.1 2.0 2 0 0 2 2 2 0 YobH-like protein Reticulon PF02453.17 KKA03754.1 - 4.6e-25 88.4 5.0 4.6e-25 88.4 5.0 1.7 2 0 0 2 2 2 1 Reticulon SKIP_SNW PF02731.15 KKA03754.1 - 0.031 13.9 0.8 0.046 13.4 0.8 1.2 1 0 0 1 1 1 0 SKIP/SNW domain DUF639 PF04842.12 KKA03754.1 - 0.082 12.3 2.5 0.17 11.3 2.5 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3685 PF12452.8 KKA03755.1 - 0.49 10.1 8.5 1.1 8.9 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) Aminotran_1_2 PF00155.21 KKA03756.1 - 5.2e-40 137.7 0.0 7e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L34 PF00468.17 KKA03758.1 - 6.7e-10 38.8 7.8 1.1e-09 38.1 7.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 ERCC4 PF02732.15 KKA03759.1 - 0.032 14.4 0.4 0.061 13.5 0.4 1.5 1 0 0 1 1 1 0 ERCC4 domain SUI1 PF01253.22 KKA03760.1 - 8.3e-11 42.3 0.0 5.4e-10 39.7 0.0 2.5 1 1 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.18 KKA03760.1 - 0.00053 19.8 3.1 0.0009 19.1 1.5 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain Pre-PUA PF17832.1 KKA03760.1 - 0.0015 19.2 9.0 0.07 13.8 7.2 3.3 2 1 0 2 2 2 1 Pre-PUA-like domain ANAPC4 PF12896.7 KKA03761.1 - 4e-08 33.0 0.2 4e-08 33.0 0.2 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Sulfate_transp PF00916.20 KKA03762.1 - 4.1e-108 361.5 12.6 5.5e-108 361.1 12.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKA03762.1 - 1.4e-05 24.7 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KKA03762.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 KKA03762.1 - 0.019 15.3 0.4 0.019 15.3 0.4 2.3 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily AA_permease PF00324.21 KKA03763.1 - 1.8e-61 208.2 36.9 3.6e-60 203.9 36.9 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKA03763.1 - 3.1e-26 92.2 34.4 7.6e-26 90.9 34.4 1.6 1 1 0 1 1 1 1 Amino acid permease Propep_M14 PF02244.16 KKA03765.1 - 0.063 13.7 3.3 5.6 7.4 0.2 3.0 2 1 0 2 2 2 0 Carboxypeptidase activation peptide CCDC32 PF14989.6 KKA03766.1 - 0.073 13.1 4.4 0.099 12.6 3.9 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing 32 BEX PF04538.12 KKA03766.1 - 0.15 12.7 4.2 3.6 8.2 1.8 2.7 1 1 1 2 2 2 0 Brain expressed X-linked like family SPAN-X PF07458.12 KKA03766.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.1 2 2 2 4 4 4 0 Sperm protein associated with nucleus, mapped to X chromosome MFS_1 PF07690.16 KKA03767.1 - 9.1e-44 149.8 35.1 9.1e-44 149.8 35.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA03767.1 - 3.7e-17 62.3 4.7 3.7e-17 62.3 4.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter INCENP_ARK-bind PF03941.15 KKA03768.1 - 1.1e-07 31.7 0.7 4.2e-07 29.8 0.9 1.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DB_JBP1 PF18526.1 KKA03768.1 - 0.11 12.5 0.8 0.27 11.1 0.8 1.7 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain TPR_1 PF00515.28 KKA03769.1 - 1.3e-12 46.9 3.5 0.00052 19.7 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKA03769.1 - 1.5e-08 34.1 0.6 0.011 15.8 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKA03769.1 - 3e-05 24.2 0.0 0.06 13.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKA03769.1 - 0.0006 19.8 1.4 0.86 9.7 0.1 3.4 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KKA03769.1 - 0.0023 17.6 0.3 0.99 9.1 0.3 3.0 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KKA03769.1 - 0.033 14.4 4.1 6.9 7.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKA03769.1 - 0.055 13.7 0.3 1.2 9.4 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_transf_15 PF01793.16 KKA03770.1 - 8.7e-113 376.8 20.7 8.7e-113 376.8 20.7 1.4 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 KKA03770.1 - 0.078 13.2 1.5 0.14 12.4 1.5 1.4 1 0 0 1 1 1 0 EGF domain Ribonuc_L-PSP PF01042.21 KKA03771.1 - 3.3e-42 143.3 0.2 3.8e-42 143.1 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GIT1_C PF12205.8 KKA03771.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term PhoLip_ATPase_C PF16212.5 KKA03772.1 - 9.4e-45 153.3 20.4 9.4e-45 153.3 20.4 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKA03772.1 - 3.1e-16 58.8 6.7 9.1e-16 57.3 6.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKA03772.1 - 1.8e-09 38.2 4.6 5.7e-06 26.8 4.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKA03772.1 - 2e-09 37.2 0.8 5.1e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKA03772.1 - 9.2e-08 32.1 0.0 4.2e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKA03772.1 - 0.26 11.0 8.7 0.023 14.4 0.9 3.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase EXS PF03124.14 KKA03773.1 - 4.8e-69 233.2 29.0 1.8e-67 228.0 27.1 2.2 2 0 0 2 2 2 2 EXS family SPX PF03105.19 KKA03773.1 - 1.9e-12 47.8 25.7 5.7e-10 39.7 3.0 4.1 3 1 1 4 4 4 4 SPX domain zf-C2H2 PF00096.26 KKA03774.1 - 2.3e-05 24.6 13.6 0.0026 18.1 1.1 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKA03774.1 - 0.00045 20.5 3.2 0.00045 20.5 3.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKA03774.1 - 0.4 11.6 17.9 0.2 12.6 3.0 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger 2-Hacid_dh_C PF02826.19 KKA03775.1 - 2.4e-25 88.9 0.0 3.5e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKA03775.1 - 0.0018 18.3 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase COX5B PF01215.19 KKA03776.1 - 1.2e-35 122.0 0.0 1.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF4781 PF16013.5 KKA03776.1 - 0.42 9.4 1.2 0.51 9.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Ribosomal_S26e PF01283.19 KKA03777.1 - 6e-49 165.0 12.8 7.1e-49 164.7 12.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1618 PF07762.14 KKA03777.1 - 0.19 12.4 0.9 0.3 11.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1618) WD40 PF00400.32 KKA03778.1 - 4.2e-16 59.0 0.3 0.0016 19.2 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03778.1 - 0.0012 19.1 0.0 43 4.5 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain COX6A PF02046.15 KKA03779.1 - 2.7e-37 127.6 1.2 3.1e-37 127.5 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Hist_deacetyl PF00850.19 KKA03780.1 - 8.6e-81 271.8 0.0 1.1e-80 271.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Fungal_trans_2 PF11951.8 KKA03781.1 - 6.7e-06 25.1 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKA03781.1 - 1.2e-05 25.3 7.1 2.3e-05 24.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pterin_4a PF01329.19 KKA03782.1 - 3e-11 43.3 0.1 3.7e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HEAT PF02985.22 KKA03783.1 - 2e-25 86.7 5.5 0.21 11.9 0.0 17.7 18 0 0 18 18 18 3 HEAT repeat HEAT_EZ PF13513.6 KKA03783.1 - 1.5e-22 79.7 4.4 0.0098 16.4 0.1 14.3 14 3 3 17 17 17 5 HEAT-like repeat HEAT_2 PF13646.6 KKA03783.1 - 2.5e-20 72.6 1.3 0.041 14.3 0.3 11.4 7 3 3 11 11 11 5 HEAT repeats Gcn1_N PF12074.8 KKA03783.1 - 2.1e-14 53.6 12.2 1.9e-08 34.0 0.0 5.2 6 1 2 8 8 8 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal CLASP_N PF12348.8 KKA03783.1 - 1.5e-09 37.8 2.4 0.038 13.5 0.0 6.3 5 2 1 7 7 7 2 CLASP N terminal Cnd1 PF12717.7 KKA03783.1 - 1.7e-07 31.4 33.8 0.008 16.2 3.1 11.0 7 3 3 10 10 10 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KKA03783.1 - 3.7e-07 30.7 4.5 0.88 10.2 0.0 8.3 9 0 0 9 9 9 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KKA03783.1 - 0.001 19.2 12.2 1.2 9.3 0.1 6.7 6 1 1 7 7 7 2 Parkin co-regulated protein DUF3385 PF11865.8 KKA03783.1 - 0.0033 17.3 13.2 8.9 6.2 0.2 8.6 7 2 2 9 9 9 1 Domain of unknown function (DUF3385) UME PF08064.13 KKA03783.1 - 0.014 15.3 4.7 10 6.1 0.1 6.6 8 0 0 8 8 8 0 UME (NUC010) domain Spore_III_AB PF09548.10 KKA03783.1 - 0.017 15.3 0.1 0.42 10.7 0.0 3.3 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF4042 PF13251.6 KKA03783.1 - 0.16 11.7 6.0 39 3.9 0.3 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) D-ser_dehydrat PF14031.6 KKA03784.1 - 2.4e-17 63.3 0.0 6e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KKA03784.1 - 3.2e-13 49.8 0.0 4.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kelch_6 PF13964.6 KKA03785.1 - 1.9e-05 24.8 0.0 5.4 7.4 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KKA03785.1 - 0.016 15.2 0.0 0.68 10.0 0.0 3.4 2 0 0 2 2 2 0 Kelch motif EMP24_GP25L PF01105.24 KKA03787.1 - 3.9e-43 147.5 1.4 4.5e-43 147.3 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 KKA03787.1 - 0.09 13.0 2.7 0.096 12.9 0.2 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Opy2 PF09463.10 KKA03788.1 - 4.4e-07 30.1 19.8 6.7e-07 29.5 19.8 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 KKA03788.1 - 0.035 13.5 0.6 0.035 13.5 0.6 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mid2 PF04478.12 KKA03788.1 - 0.069 13.0 1.9 0.094 12.6 0.5 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Beta-APP PF03494.13 KKA03788.1 - 0.11 12.3 4.3 0.26 11.2 4.3 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Glycophorin_A PF01102.18 KKA03788.1 - 0.54 10.5 4.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Glycophorin A Transketolase_N PF00456.21 KKA03789.1 - 3.3e-156 519.4 0.0 8.8e-156 518.0 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KKA03789.1 - 3.4e-47 160.4 0.0 8e-47 159.2 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKA03789.1 - 2.1e-12 47.0 0.0 6.6e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KKA03789.1 - 0.0043 16.3 0.0 0.0075 15.5 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KKA03789.1 - 0.023 14.5 1.7 0.36 10.6 0.9 3.0 3 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UDPG_MGDP_dh_N PF03721.14 KKA03789.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Not3 PF04065.15 KKA03790.1 - 1.2e-53 182.0 20.1 1.2e-53 182.0 20.1 2.7 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KKA03790.1 - 3.3e-19 69.3 5.8 3.3e-19 69.3 5.8 2.5 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family NAD_binding_4 PF07993.12 KKA03791.1 - 2.9e-68 229.8 0.0 4.3e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KKA03791.1 - 1.1e-67 228.5 0.0 1.5e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KKA03791.1 - 1.8e-15 57.0 0.0 4.4e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KKA03791.1 - 1.4e-12 47.6 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKA03791.1 - 9.1e-06 24.9 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KKA03791.1 - 4.6e-05 24.3 0.0 0.00027 21.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KKA03791.1 - 0.0016 17.9 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KKA03791.1 - 0.18 11.7 0.0 2.7 7.8 0.0 2.4 1 1 0 1 1 1 0 NAD(P)H-binding B12-binding_2 PF02607.17 KKA03792.1 - 0.18 12.3 0.0 0.81 10.2 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain SNF2_N PF00176.23 KKA03793.1 - 2.4e-54 184.4 0.2 7.1e-54 182.8 0.2 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA03793.1 - 1.2e-18 67.4 0.0 1.7e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KKA03793.1 - 3.2e-07 30.1 9.6 3.2e-07 30.1 9.6 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KKA03793.1 - 1.3e-06 28.3 0.0 4.5e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 KKA03793.1 - 0.00039 20.2 9.3 0.00039 20.2 9.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKA03793.1 - 0.00045 20.0 7.3 0.00045 20.0 7.3 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KKA03793.1 - 0.0041 17.2 3.2 0.0041 17.2 3.2 2.2 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KKA03793.1 - 0.0082 16.3 9.2 0.0082 16.3 9.2 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KKA03793.1 - 0.012 16.0 9.7 0.012 16.0 9.7 2.5 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KKA03793.1 - 0.015 15.1 8.7 0.015 15.1 8.7 2.1 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKA03793.1 - 0.25 11.4 10.1 0.82 9.7 10.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 KKA03793.1 - 0.45 10.6 13.3 0.41 10.7 1.5 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain DnaJ-X PF14308.6 KKA03794.1 - 8.5e-51 172.4 17.2 8.5e-51 172.4 17.2 2.1 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KKA03794.1 - 1.4e-20 73.2 1.5 1.4e-20 73.2 1.5 2.7 3 0 0 3 3 3 1 DnaJ domain Auxin_canalis PF05703.11 KKA03794.1 - 0.13 12.2 6.7 0.78 9.6 0.5 2.2 2 0 0 2 2 2 0 Auxin canalisation Cytochrom_C PF00034.21 KKA03794.1 - 0.13 13.4 1.0 0.58 11.3 1.0 2.2 1 0 0 1 1 1 0 Cytochrome c DUF4478 PF14793.6 KKA03794.1 - 0.37 10.7 2.1 0.43 10.5 0.3 2.0 3 0 0 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF3492 PF11997.8 KKA03794.1 - 1.8 8.3 9.7 0.11 12.2 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Metallophos PF00149.28 KKA03795.1 - 5.1e-07 30.4 8.0 2.9e-06 27.9 8.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.29 KKA03796.1 - 5.9e-35 120.6 0.0 3.1e-34 118.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA03796.1 - 4.9e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KKA03796.1 - 7.3e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKA03796.1 - 1.1e-05 25.5 0.0 3.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 KKA03796.1 - 0.00018 21.4 0.0 0.00049 20.0 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KKA03796.1 - 0.00038 20.7 2.1 0.0033 17.7 0.0 3.1 3 1 2 5 5 4 1 AAA domain AAA_16 PF13191.6 KKA03796.1 - 0.0011 19.4 0.1 0.0082 16.5 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KKA03796.1 - 0.0014 18.1 0.0 0.0039 16.6 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KKA03796.1 - 0.0031 17.5 0.1 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKA03796.1 - 0.0068 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 KKA03796.1 - 0.011 15.4 0.0 0.67 9.6 0.0 2.8 2 0 0 2 2 2 0 Guanylate kinase IstB_IS21 PF01695.17 KKA03796.1 - 0.022 14.5 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KKA03796.1 - 0.028 14.1 0.0 0.085 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKA03796.1 - 0.099 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KKA03796.1 - 0.12 11.8 0.7 8.7 5.7 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein TauD PF02668.16 KKA03797.1 - 1.4e-35 123.4 0.0 1.9e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Csd3_N PF18059.1 KKA03797.1 - 0.085 13.4 0.1 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Csd3 N-terminal Toxin_14 PF07829.11 KKA03797.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.1 3 0 0 3 3 3 0 Alpha-A conotoxin PIVA-like protein DUF1462 PF07315.11 KKA03798.1 - 0.04 14.2 0.3 0.2 11.9 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) EMC3_TMCO1 PF01956.16 KKA03798.1 - 0.31 10.8 15.3 2.5 7.8 0.7 3.4 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like bZIP_1 PF00170.21 KKA03799.1 - 2.9e-09 36.9 10.5 7.9e-09 35.5 10.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKA03799.1 - 1.5e-05 25.0 8.9 1.5e-05 25.0 8.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKA03799.1 - 0.044 14.3 5.1 0.044 14.3 5.1 2.3 3 0 0 3 3 3 0 bZIP Maf transcription factor HALZ PF02183.18 KKA03799.1 - 3.4 8.0 10.9 0.11 12.7 3.8 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.25 KKA03800.1 - 2.4e-52 177.9 4.2 1.2e-51 175.6 4.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03800.1 - 4.6e-15 55.6 0.3 7.7e-15 54.9 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKA03800.1 - 0.0025 17.8 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family She9_MDM33 PF05546.11 KKA03801.1 - 2.5e-53 180.8 9.9 5.1e-53 179.8 9.9 1.5 1 0 0 1 1 1 1 She9 / Mdm33 family ASFV_J13L PF05568.11 KKA03801.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein FOXO_KIX_bdg PF16675.5 KKA03801.1 - 0.39 11.1 5.8 4.5 7.6 0.4 2.9 2 1 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 CK_II_beta PF01214.18 KKA03801.1 - 0.59 9.9 5.5 3 7.6 0.4 2.6 3 0 0 3 3 3 0 Casein kinase II regulatory subunit DUF3482 PF11981.8 KKA03801.1 - 0.88 8.9 5.9 1.5 8.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) DUF4094 PF13334.6 KKA03801.1 - 1 9.8 12.0 6.6 7.2 0.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) AAA PF00004.29 KKA03802.1 - 1.3e-45 155.0 0.0 3.4e-45 153.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKA03802.1 - 5e-11 42.4 0.5 1.3e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KKA03802.1 - 2.4e-09 37.3 0.1 1.2e-08 35.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKA03802.1 - 9.1e-08 32.4 0.2 2.3e-07 31.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKA03802.1 - 2.4e-07 31.3 0.2 2.3e-05 24.8 0.0 3.0 3 1 1 4 4 2 1 AAA ATPase domain NTPase_1 PF03266.15 KKA03802.1 - 4e-05 23.6 0.2 0.00019 21.4 0.0 2.2 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 KKA03802.1 - 5.5e-05 23.5 3.4 0.003 17.9 1.0 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKA03802.1 - 0.00012 21.3 0.0 0.00024 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KKA03802.1 - 0.00025 20.8 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KKA03802.1 - 0.00039 20.4 0.0 0.00083 19.4 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KKA03802.1 - 0.00052 20.6 0.1 0.0063 17.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKA03802.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KKA03802.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KKA03802.1 - 0.0015 18.6 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KKA03802.1 - 0.0023 17.7 0.2 0.13 11.9 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KKA03802.1 - 0.0027 17.2 0.1 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KKA03802.1 - 0.0034 17.8 0.0 0.0095 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KKA03802.1 - 0.0039 16.6 0.0 0.26 10.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 KKA03802.1 - 0.0039 16.4 0.0 0.0086 15.3 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KKA03802.1 - 0.0061 16.8 0.1 0.02 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KKA03802.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKA03802.1 - 0.0073 15.7 0.1 0.02 14.3 0.1 1.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KKA03802.1 - 0.0099 15.8 0.2 0.059 13.3 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_11 PF13086.6 KKA03802.1 - 0.01 15.6 0.2 0.054 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KKA03802.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKA03802.1 - 0.012 15.8 0.0 0.037 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KKA03802.1 - 0.027 14.4 0.8 0.23 11.3 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KKA03802.1 - 0.027 14.2 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 KKA03802.1 - 0.063 13.1 0.8 0.22 11.3 0.0 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KKA03802.1 - 0.067 12.3 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KKA03802.1 - 0.093 12.3 1.8 0.36 10.4 0.1 2.3 2 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KKA03802.1 - 0.11 13.0 5.5 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKA03802.1 - 0.11 12.8 0.2 0.36 11.2 0.1 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KKA03802.1 - 0.27 11.8 2.9 0.39 11.2 0.0 2.6 2 2 0 2 2 2 0 ABC transporter Glyco_transf_22 PF03901.17 KKA03803.1 - 1.2e-45 156.5 41.7 1.6e-45 156.1 41.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BrnT_toxin PF04365.13 KKA03803.1 - 0.19 12.1 0.1 0.5 10.7 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system PAT1 PF09770.9 KKA03804.1 - 0.86 7.8 3.8 0.5 8.6 0.7 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Utp12 PF04003.12 KKA03805.1 - 2.8e-09 37.2 1.6 5.7e-09 36.2 1.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKA03805.1 - 0.0046 17.2 1.5 1.6 9.0 0.1 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Rubredoxin_C PF18267.1 KKA03805.1 - 0.074 13.0 1.5 0.26 11.3 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain Pribosyltran PF00156.27 KKA03806.1 - 2.4e-06 27.2 0.0 5.6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain EC042_2821 PF18740.1 KKA03806.1 - 0.00062 19.7 2.1 0.001 19.0 1.5 1.6 1 1 1 2 2 2 1 EC042_2821-lke REase IU_nuc_hydro PF01156.19 KKA03807.1 - 1.6e-21 77.2 0.0 2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DIT1_PvcA PF05141.12 KKA03808.1 - 3.7e-91 305.4 0.0 5.7e-91 304.8 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein SHS2_Rpb7-N PF03876.17 KKA03809.1 - 5.9e-15 55.4 0.0 9.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KKA03809.1 - 6e-14 52.1 0.0 8.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KKA03809.1 - 0.00024 21.3 0.0 0.00042 20.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.18 KKA03810.1 - 1.4e-31 109.4 0.0 2.2e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.28 KKA03811.1 - 1.5e-125 419.4 0.1 2.6e-125 418.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKA03811.1 - 6.1e-65 218.5 0.2 1.1e-64 217.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKA03811.1 - 3.9e-50 170.1 0.2 3.9e-50 170.1 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKA03811.1 - 3.4e-34 117.1 0.3 7.6e-34 116.0 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KKA03811.1 - 2e-24 85.5 0.1 5.5e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KKA03811.1 - 2.5e-20 72.5 1.0 6.3e-20 71.2 1.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KKA03811.1 - 1.1e-14 54.7 11.9 1.1e-14 54.7 11.9 3.0 3 1 0 3 3 3 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KKA03811.1 - 0.0097 16.6 0.1 0.0097 16.6 0.1 2.9 3 0 0 3 3 3 1 MRN-interacting protein RNA_pol_Rpb2_45 PF10385.9 KKA03811.1 - 0.19 12.0 2.8 1.3 9.3 1.0 2.7 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Ribosomal_L23 PF00276.20 KKA03812.1 - 1.6e-07 31.6 0.1 5.5e-07 29.9 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L23 DZR PF12773.7 KKA03813.1 - 0.044 13.8 7.0 7.4 6.7 7.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF2039 PF10217.9 KKA03813.1 - 1.5 9.2 6.5 0.49 10.8 2.9 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Mss4 PF04421.13 KKA03813.1 - 1.7 8.9 5.7 0.64 10.2 1.6 2.4 2 0 0 2 2 2 0 Mss4 protein zinc_ribbon_10 PF10058.9 KKA03813.1 - 8.8 6.1 10.6 0.98 9.2 3.1 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Choline_transpo PF04515.12 KKA03814.1 - 5e-74 249.4 24.2 5e-74 249.4 24.2 2.9 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF4064 PF13273.6 KKA03814.1 - 6.4e-05 23.2 6.2 6.4e-05 23.2 6.2 4.5 3 2 2 6 6 6 1 Protein of unknown function (DUF4064) PspB PF06667.12 KKA03814.1 - 0.057 13.5 0.1 0.25 11.4 0.1 2.1 1 0 0 1 1 1 0 Phage shock protein B IMP2_N PF18590.1 KKA03815.1 - 0.042 14.4 0.1 8.7 7.0 0.0 3.4 3 0 0 3 3 3 0 Immune Mapped Protein 2 (IMP2) N-terminal domain Cullin_Nedd8 PF10557.9 KKA03815.1 - 0.058 13.4 0.1 0.42 10.7 0.0 2.6 2 0 0 2 2 2 0 Cullin protein neddylation domain PfUIS3 PF11567.8 KKA03816.1 - 0.69 10.3 13.1 0.035 14.5 5.1 2.6 2 1 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein TRAPPC9-Trs120 PF08626.11 KKA03817.1 - 9.7e-25 86.2 36.9 1.2e-12 46.2 1.4 4.2 2 2 2 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Proteasome PF00227.26 KKA03818.1 - 2.8e-47 160.7 0.3 3.4e-47 160.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KKA03818.1 - 7.1e-09 34.9 0.1 7.1e-09 34.9 0.1 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Formyl_trans_N PF00551.19 KKA03819.1 - 4.4e-44 150.4 0.2 5.4e-44 150.1 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase cobW PF02492.19 KKA03820.1 - 3.5e-43 147.2 2.5 5.2e-43 146.7 2.5 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KKA03820.1 - 2.2e-07 30.7 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.23 KKA03820.1 - 1.9e-05 24.7 0.2 6.9e-05 22.9 0.2 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 KKA03820.1 - 0.00013 21.9 0.1 0.00041 20.3 0.1 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KKA03820.1 - 0.00071 19.5 1.7 0.037 13.9 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KKA03820.1 - 0.00086 19.1 0.8 0.0016 18.3 0.7 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KKA03820.1 - 0.0015 18.8 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKA03820.1 - 0.0023 17.6 0.0 0.0074 16.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KKA03820.1 - 0.0037 17.8 0.0 0.02 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KKA03820.1 - 0.0078 16.2 0.1 0.034 14.2 0.1 2.1 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KKA03820.1 - 0.031 13.3 0.3 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KKA03820.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KKA03820.1 - 0.098 13.2 0.3 0.45 11.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter T2SSE PF00437.20 KKA03820.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KKA03820.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKA03820.1 - 2 8.9 8.6 8.1 6.9 8.6 2.2 1 1 0 1 1 1 0 AAA domain zf-MIZ PF02891.20 KKA03821.1 - 7.3e-22 76.9 7.4 7.3e-22 76.9 7.4 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger PINIT PF14324.6 KKA03821.1 - 8.9e-19 68.3 0.9 2.1e-18 67.1 0.9 1.7 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 KKA03821.1 - 1.1e-10 41.2 2.2 2.2e-10 40.2 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKA03821.1 - 0.0049 16.9 2.7 0.0062 16.5 0.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Pox_G9-A16 PF03003.16 KKA03821.1 - 0.013 15.2 3.2 0.028 14.1 3.2 1.5 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 Prok-RING_4 PF14447.6 KKA03821.1 - 0.23 11.3 1.6 0.56 10.1 1.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KKA03821.1 - 0.3 10.9 7.3 0.46 10.4 5.8 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKA03821.1 - 0.84 10.0 7.8 0.2 12.0 4.5 1.8 2 0 0 2 2 2 0 Ring finger domain ICMT PF04140.14 KKA03822.1 - 3.6e-25 88.2 1.8 4.7e-25 87.8 0.7 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKA03822.1 - 1.3e-11 44.9 2.9 3e-11 43.6 2.9 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KKA03822.1 - 4.6e-05 23.0 0.7 5.9e-05 22.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KKA03822.1 - 0.00097 18.7 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 NnrU protein RNase_H_2 PF13482.6 KKA03823.1 - 0.012 15.7 4.0 1.1 9.2 0.5 2.2 1 1 1 2 2 2 0 RNase_H superfamily DER1 PF04511.15 KKA03824.1 - 1.3e-16 61.1 16.9 1.7e-16 60.7 16.9 1.1 1 0 0 1 1 1 1 Der1-like family Nop25 PF09805.9 KKA03825.1 - 8.7e-32 110.5 17.6 8.7e-32 110.5 17.6 2.2 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) GIDA_assoc PF13932.6 KKA03825.1 - 2.8 8.1 15.4 0.27 11.4 9.8 2.0 1 1 1 2 2 2 0 GidA associated domain EXS PF03124.14 KKA03826.1 - 1.6e-16 60.6 19.9 2e-16 60.2 19.9 1.2 1 0 0 1 1 1 1 EXS family MDM10 PF12519.8 KKA03828.1 - 1.2e-30 106.9 14.4 4e-30 105.1 14.4 1.8 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 PUF PF00806.19 KKA03829.1 - 1.1e-29 100.5 11.7 7.9e-06 25.3 0.0 8.0 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat CPL PF08144.11 KKA03829.1 - 0.017 15.4 3.5 1 9.7 1.2 3.7 2 2 1 3 3 3 0 CPL (NUC119) domain DUF4286 PF14114.6 KKA03829.1 - 0.049 14.1 2.4 0.32 11.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) HTH_19 PF12844.7 KKA03829.1 - 0.076 13.1 0.2 0.26 11.4 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain FAD_binding_7 PF03441.14 KKA03829.1 - 0.79 9.2 2.4 0.99 8.8 0.4 2.1 3 0 0 3 3 3 0 FAD binding domain of DNA photolyase DUF3385 PF11865.8 KKA03829.1 - 0.81 9.6 4.4 0.55 10.1 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) 3Beta_HSD PF01073.19 KKA03830.1 - 7.6e-15 54.7 0.0 1.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKA03830.1 - 8.9e-15 54.8 0.0 1.2e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKA03830.1 - 6e-12 45.3 0.1 1.3e-10 40.9 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KKA03830.1 - 3.4e-08 33.6 0.0 1.3e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKA03830.1 - 7.3e-08 31.9 0.2 2.8e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KKA03830.1 - 1.7e-05 24.4 0.2 5.2e-05 22.8 0.2 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KKA03830.1 - 4e-05 23.6 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KKA03830.1 - 0.00022 21.8 0.0 0.00062 20.3 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KKA03830.1 - 0.00042 19.8 0.0 0.0095 15.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KKA03830.1 - 0.00086 18.9 0.0 0.078 12.5 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 KKA03830.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KKA03830.1 - 0.037 14.5 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KKA03831.1 - 3.2e-17 62.8 0.0 4.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKA03831.1 - 4.9e-11 42.3 0.1 6.1e-10 38.7 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KKA03831.1 - 4.5e-09 35.7 0.1 6.6e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKA03831.1 - 6.7e-09 35.9 0.4 1.3e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KKA03831.1 - 2.6e-06 27.0 0.0 5.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KKA03831.1 - 8e-06 25.6 0.4 0.051 13.1 0.1 2.3 2 1 0 2 2 2 2 NmrA-like family adh_short_C2 PF13561.6 KKA03831.1 - 8.4e-05 22.2 0.2 0.00019 21.1 0.2 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KKA03831.1 - 0.00011 21.7 0.2 0.00069 19.1 0.2 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KKA03831.1 - 0.00035 21.1 0.0 0.0014 19.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KKA03831.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KKA03831.1 - 0.12 12.4 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ERG4_ERG24 PF01222.17 KKA03832.1 - 3.2e-164 546.8 24.4 3.7e-164 546.6 24.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Rsc14 PF08586.10 KKA03833.1 - 0.0011 19.7 0.6 0.0098 16.7 0.1 2.6 2 1 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit Proteasome PF00227.26 KKA03834.1 - 2.4e-37 128.3 0.3 2.8e-36 124.8 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 KKA03834.1 - 6.1e-15 54.6 0.0 1.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SHD1 PF03983.12 KKA03835.1 - 1.8e-30 104.5 0.0 4.4e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KKA03835.1 - 8.9e-23 79.7 9.9 3.9e-08 32.8 0.0 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KKA03835.1 - 5.6e-21 74.1 7.8 2.5e-07 30.4 0.0 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KKA03835.1 - 4.1e-18 64.8 1.6 0.00042 20.0 0.0 4.6 4 1 0 4 4 4 3 Variant SH3 domain SAM_1 PF00536.30 KKA03835.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1720 PF08226.11 KKA03835.1 - 0.19 12.1 78.1 0.27 11.7 6.7 7.1 5 1 2 7 7 7 0 Domain of unknown function (DUF1720) HAUS-augmin3 PF14932.6 KKA03835.1 - 1.2 8.7 13.0 1.9 8.0 4.9 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Aconitase PF00330.20 KKA03836.1 - 3.3e-159 530.8 0.0 4.1e-159 530.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKA03836.1 - 8.4e-44 149.1 0.0 1.9e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KKA03836.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) WD40 PF00400.32 KKA03837.1 - 4.1e-24 84.4 9.3 5.2e-08 33.4 1.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03837.1 - 1.5e-16 60.5 0.8 1.1e-05 25.6 0.0 6.5 4 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain MDM31_MDM32 PF08118.11 KKA03838.1 - 8.3e-20 70.9 11.6 8.3e-20 70.9 11.6 3.0 1 1 0 2 2 2 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 KKA03839.1 - 3.4e-06 27.0 0.2 9.3e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KKA03839.1 - 0.045 13.6 0.3 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 KH domain AAA PF00004.29 KKA03840.1 - 0.074 13.5 0.0 0.074 13.5 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IGFL PF14653.6 KKA03840.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Insulin growth factor-like family TFIID-18kDa PF02269.16 KKA03841.1 - 3.6e-18 65.4 2.3 2.1e-09 37.3 0.1 2.6 1 1 1 2 2 2 2 Transcription initiation factor IID, 18kD subunit A_thal_3526 PF09713.10 KKA03841.1 - 0.078 13.2 0.7 0.47 10.7 0.0 2.5 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) TPK_catalytic PF04263.16 KKA03842.1 - 6.9e-26 90.7 1.4 1.7e-25 89.4 1.4 1.6 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KKA03842.1 - 0.00055 19.6 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CoA_binding PF02629.19 KKA03843.1 - 2.5e-23 82.6 0.8 7.3e-23 81.1 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KKA03843.1 - 2.8e-18 66.2 0.2 4.3e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.6 KKA03843.1 - 1.9e-08 34.8 0.0 3.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 KKA03843.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain DapB_N PF01113.20 KKA03843.1 - 3.3e-05 24.0 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Actin PF00022.19 KKA03844.1 - 3.2e-21 75.4 1.7 1.4e-11 43.7 0.4 4.2 3 1 0 3 3 3 3 Actin MreB_Mbl PF06723.13 KKA03844.1 - 7.3e-05 21.7 0.0 0.072 11.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KKA03844.1 - 0.034 14.6 0.1 1 9.8 0.0 2.8 3 0 0 3 3 3 0 Cell division protein FtsA tRNA-synt_2b PF00587.25 KKA03845.1 - 6.4e-36 124.0 0.0 1.1e-35 123.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKA03845.1 - 3.5e-16 59.1 0.1 8e-16 58.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KKA03845.1 - 1.7e-12 47.2 0.0 3.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KKA03845.1 - 5.4e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain ROF PF07073.12 KKA03845.1 - 0.29 11.3 1.3 1.8 8.8 0.0 2.8 3 0 0 3 3 3 0 Modulator of Rho-dependent transcription termination (ROF) Iso_dh PF00180.20 KKA03846.1 - 4e-90 302.4 0.4 5.3e-90 302.1 0.4 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IDH PF03971.14 KKA03846.1 - 0.018 13.5 0.0 0.024 13.1 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase Gifsy-2 PF13856.6 KKA03846.1 - 0.052 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage HSF_DNA-bind PF00447.17 KKA03847.1 - 8.1e-22 77.7 5.8 8.1e-22 77.7 5.8 2.3 3 0 0 3 3 3 1 HSF-type DNA-binding ThiF PF00899.21 KKA03848.1 - 3.9e-65 219.6 0.2 5.5e-65 219.1 0.2 1.1 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 KKA03848.1 - 0.00098 19.5 0.1 0.0042 17.5 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding UBA_e1_thiolCys PF10585.9 KKA03848.1 - 0.0012 18.8 13.7 0.022 14.7 0.9 3.2 2 1 2 4 4 4 3 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 KKA03848.1 - 0.028 15.0 1.8 0.092 13.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KKA03848.1 - 0.058 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 KKA03848.1 - 0.84 10.4 4.8 10 6.9 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin fold domain RhoGAP PF00620.27 KKA03849.1 - 2.8e-31 108.4 4.7 2.8e-30 105.1 4.7 2.4 1 1 0 1 1 1 1 RhoGAP domain BAR PF03114.18 KKA03850.1 - 7.7e-53 179.6 6.8 9.9e-53 179.2 6.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KKA03850.1 - 5e-15 54.8 0.0 8.8e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKA03850.1 - 5.7e-12 45.3 0.1 1e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKA03850.1 - 1.3e-09 37.6 0.0 2.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KKA03850.1 - 0.06 12.9 8.0 0.67 9.5 8.0 2.1 1 1 0 1 1 1 0 Vps5 C terminal like BRE1 PF08647.11 KKA03850.1 - 1.4 9.0 15.4 0.063 13.3 1.6 3.0 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase PHM7_cyt PF14703.6 KKA03850.1 - 3.5 7.8 6.1 0.86 9.8 1.5 2.2 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter GTP_EFTU PF00009.27 KKA03851.1 - 6.4e-38 130.3 0.0 1.7e-37 128.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKA03851.1 - 2.9e-05 24.1 0.7 0.00031 20.8 0.0 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 KKA03851.1 - 0.0043 17.3 3.2 0.027 14.8 0.4 3.3 2 1 1 3 3 3 1 Elongation factor Tu C-terminal domain Roc PF08477.13 KKA03851.1 - 0.036 14.3 3.1 2.9 8.1 0.1 3.8 3 2 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 KKA03851.1 - 0.086 13.2 0.0 0.3 11.5 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Cullin PF00888.22 KKA03852.1 - 1.3e-34 119.9 43.2 1.5e-34 119.7 43.2 1.0 1 0 0 1 1 1 1 Cullin family TcpA PF05946.12 KKA03852.1 - 0.11 12.6 0.3 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA TFIIF_beta_N PF17683.1 KKA03853.1 - 6.1e-34 117.6 12.5 1.1e-32 113.6 12.5 2.6 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KKA03853.1 - 3.3e-27 94.4 1.0 6.8e-27 93.4 1.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain DUF4342 PF14242.6 KKA03853.1 - 1.2 9.1 6.3 0.27 11.3 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Prp18 PF02840.15 KKA03854.1 - 3.2e-17 62.9 0.2 3.2e-17 62.9 0.2 2.6 1 1 0 2 2 2 1 Prp18 domain eIF3_subunit PF08597.10 KKA03854.1 - 0.014 15.4 13.2 0.021 14.7 13.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CSG2 PF16965.5 KKA03854.1 - 0.031 13.2 1.9 0.044 12.7 1.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4112 PF13430.6 KKA03855.1 - 6e-23 81.1 0.1 8e-23 80.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTP_transf_like PF01467.26 KKA03856.1 - 1.1e-12 48.3 0.0 6.7e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 Cytidylyltransferase-like HIGH_NTase1_ass PF16581.5 KKA03856.1 - 0.068 13.2 7.3 0.036 14.1 3.9 2.0 1 1 0 2 2 2 0 Cytidyltransferase-related C-terminal region VAPB_antitox PF02697.14 KKA03856.1 - 0.22 12.3 0.2 0.22 12.3 0.2 2.4 3 1 0 3 3 3 0 Putative antitoxin CTP_transf_like PF01467.26 KKA03857.1 - 6.5e-32 110.7 0.0 1.1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like PALP PF00291.25 KKA03858.1 - 4.6e-61 206.8 0.0 5.4e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TrbL PF04610.14 KKA03859.1 - 0.19 11.4 0.1 0.19 11.4 0.1 3.3 4 1 1 5 5 5 0 TrbL/VirB6 plasmid conjugal transfer protein PITH PF06201.13 KKA03861.1 - 5.3e-24 85.2 0.3 7e-24 84.8 0.3 1.2 1 0 0 1 1 1 1 PITH domain ALAD PF00490.21 KKA03862.1 - 6.4e-117 390.2 0.0 7.8e-117 390.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Snf7 PF03357.21 KKA03863.1 - 1.3e-28 99.7 19.7 1.3e-28 99.7 19.7 1.3 1 1 0 1 1 1 1 Snf7 Aminotran_3 PF00202.21 KKA03864.1 - 2.7e-103 345.8 0.0 3.3e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III zf-rbx1 PF12678.7 KKA03865.1 - 0.00046 20.4 0.4 0.00046 20.4 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKA03865.1 - 0.0012 19.1 2.0 0.0012 19.1 2.0 2.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KKA03865.1 - 0.0056 16.4 5.4 0.09 12.5 5.4 2.6 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KKA03865.1 - 0.026 14.6 1.7 0.035 14.1 0.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KKA03865.1 - 0.14 12.0 0.3 0.14 12.0 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Titin_Ig-rpts PF06582.12 KKA03865.1 - 4 7.5 6.4 5 7.1 1.6 2.5 2 0 0 2 2 2 0 Titin repeat CSTF2_hinge PF14327.6 KKA03866.1 - 1.5e-07 31.7 0.9 1.5e-07 31.7 0.9 2.7 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KKA03866.1 - 0.00011 21.7 10.2 0.00034 20.1 10.2 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Dehydrin PF00257.19 KKA03866.1 - 0.01 16.4 0.1 0.021 15.4 0.1 1.4 1 0 0 1 1 1 0 Dehydrin APG6_N PF17675.1 KKA03866.1 - 0.14 12.7 8.8 0.25 11.9 0.1 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region RRM_1 PF00076.22 KKA03867.1 - 3.5e-13 49.2 0.0 7.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KKA03867.1 - 0.00047 19.7 0.8 0.002 17.7 0.8 2.2 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KKA03867.1 - 0.64 10.5 8.9 0.1 13.1 3.3 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 TFIIS_C PF01096.18 KKA03868.1 - 2.1e-19 69.1 4.1 2.1e-19 69.1 4.1 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 KKA03868.1 - 2.3e-17 63.5 1.1 2.3e-17 63.5 1.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KKA03868.1 - 2.4e-09 37.0 1.5 2.4e-09 37.0 1.5 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain EMP24_GP25L PF01105.24 KKA03868.1 - 0.014 15.4 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PALP PF00291.25 KKA03869.1 - 5e-60 203.4 0.0 6.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KKA03869.1 - 1.5e-19 70.2 0.2 2.7e-11 43.7 0.1 2.6 2 0 0 2 2 2 2 CBS domain PQ-loop PF04193.14 KKA03870.1 - 5.1e-31 106.2 16.1 4.6e-16 58.3 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 KKA03870.1 - 0.0026 17.8 0.2 0.0026 17.8 0.2 3.3 2 2 1 3 3 3 1 Sugar efflux transporter for intercellular exchange Nmad2 PF18753.1 KKA03870.1 - 0.083 12.3 0.3 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Nucleotide modification associated domain 2 ER_lumen_recept PF00810.18 KKA03870.1 - 0.084 13.7 4.3 15 6.4 0.0 2.7 1 1 1 2 2 2 0 ER lumen protein retaining receptor ETRAMP PF09716.10 KKA03870.1 - 0.24 11.5 1.3 8.9 6.5 0.1 3.2 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SBE2 PF17076.5 KKA03871.1 - 5.5e-48 163.9 36.5 5.5e-48 163.9 36.5 3.7 1 1 2 3 3 3 2 SBE2, cell-wall formation BBS1 PF14779.6 KKA03871.1 - 1.4 8.3 7.4 2.9 7.3 1.1 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 1 RIH_assoc PF08454.11 KKA03872.1 - 0.18 11.7 1.4 1.2 9.1 0.3 2.7 2 0 0 2 2 2 0 RyR and IP3R Homology associated SBE2 PF17076.5 KKA03872.1 - 1.6 6.8 36.0 4.7 5.3 32.9 2.6 2 1 0 2 2 2 0 SBE2, cell-wall formation Pkinase PF00069.25 KKA03873.1 - 4.2e-64 216.5 0.0 7.7e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03873.1 - 8.4e-48 162.9 0.0 1.6e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKA03873.1 - 0.0017 17.2 1.4 0.0042 15.9 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KKA03873.1 - 0.004 16.5 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FidL_like PF15941.5 KKA03874.1 - 0.17 12.3 4.5 12 6.4 0.4 3.3 1 1 1 2 2 2 0 FidL-like putative membrane protein SNARE PF05739.19 KKA03875.1 - 6.6e-12 45.2 5.3 2.8e-11 43.2 0.0 3.1 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 KKA03875.1 - 1.4e-08 35.0 13.4 1.5e-08 35.0 6.6 2.3 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 KKA03875.1 - 0.0031 17.2 8.7 0.026 14.2 0.1 2.4 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.9 KKA03875.1 - 0.033 13.9 12.6 0.069 12.9 3.2 2.4 1 1 1 2 2 2 0 Membrane fusion protein Use1 MCPsignal PF00015.21 KKA03875.1 - 0.21 11.4 5.0 3.6 7.4 0.2 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2203 PF09969.9 KKA03875.1 - 1 10.1 4.5 13 6.6 0.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 KKA03875.1 - 1.2 9.6 8.3 2.5 8.6 3.7 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region AI-2E_transport PF01594.16 KKA03875.1 - 1.3 8.1 9.0 0.89 8.6 3.8 2.1 2 0 0 2 2 2 0 AI-2E family transporter DUF1664 PF07889.12 KKA03875.1 - 3 7.9 10.7 3.2 7.8 0.8 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KKA03875.1 - 3.7 8.0 11.1 3 8.3 1.6 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KKA03875.1 - 4.2 8.1 8.8 5.6 7.7 0.9 3.6 3 1 1 4 4 4 0 SlyX ABC2_membrane_3 PF12698.7 KKA03875.1 - 6.2 5.8 16.6 19 4.2 16.6 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Synaptobrevin PF00957.21 KKA03875.1 - 8.5 6.2 14.4 0.19 11.6 4.0 2.6 3 0 0 3 3 3 0 Synaptobrevin WD40 PF00400.32 KKA03876.1 - 1.3e-37 127.1 14.6 4.5e-07 30.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKA03876.1 - 6.5e-13 48.8 4.5 0.012 15.9 0.1 4.8 2 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KKA03876.1 - 0.035 13.2 0.3 0.035 13.2 0.3 2.2 3 0 0 3 3 3 0 Coatomer WD associated region IKI3 PF04762.12 KKA03876.1 - 0.12 10.3 1.4 0.2 9.6 1.4 1.5 1 0 0 1 1 1 0 IKI3 family FAD_binding_6 PF00970.24 KKA03877.1 - 2.7e-07 30.9 0.0 1.1e-05 25.7 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain tRNA-synt_1b PF00579.25 KKA03878.1 - 1e-68 231.8 1.0 1.5e-68 231.3 1.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TLD PF07534.16 KKA03878.1 - 0.067 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 TLD TAF6_C PF07571.13 KKA03878.1 - 0.4 11.0 2.0 1.2 9.5 0.2 2.7 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Hira PF07569.11 KKA03879.1 - 2.1e-65 220.6 0.8 6.6e-65 218.9 0.8 1.9 1 0 0 1 1 1 1 TUP1-like enhancer of split CK_II_beta PF01214.18 KKA03880.1 - 2.3e-52 177.4 2.8 1.4e-42 145.5 0.4 2.2 2 0 0 2 2 2 2 Casein kinase II regulatory subunit STD1 PF17235.2 KKA03881.1 - 6.3e-61 205.6 5.8 1.1e-60 204.8 5.6 1.6 1 1 0 1 1 1 1 STD1/MTH1 DUF4252 PF14060.6 KKA03882.1 - 0.087 12.7 0.6 0.28 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) CUE PF02845.16 KKA03883.1 - 1e-05 25.1 0.0 3.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 CUE domain HAGH_C PF16123.5 KKA03884.1 - 1.2e-16 61.0 0.3 2.3e-16 60.1 0.3 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KKA03884.1 - 6.8e-07 29.5 4.9 1.4e-05 25.2 4.9 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKA03884.1 - 6.6e-05 22.5 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.20 KKA03885.1 - 4.2e-43 147.0 0.1 1.4e-42 145.3 0.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKA03885.1 - 1.2e-26 94.3 0.1 2.1e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKA03885.1 - 2.4e-07 31.1 10.9 0.034 14.6 1.3 5.5 4 1 0 4 4 4 2 Heavy-metal-associated domain Glycohydro_20b2 PF14845.6 KKA03885.1 - 0.13 12.9 0.5 0.33 11.6 0.5 1.7 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like AKAP95 PF04988.12 KKA03885.1 - 4.3 7.5 9.1 0.24 11.6 1.2 3.0 4 0 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Acyltransferase PF01553.21 KKA03886.1 - 7.4e-07 28.9 0.0 0.005 16.5 0.0 2.9 3 0 0 3 3 3 2 Acyltransferase DUF1509 PF07420.11 KKA03886.1 - 0.032 13.2 0.5 0.05 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) NdhL PF10716.9 KKA03886.1 - 0.17 11.8 1.6 0.48 10.4 1.6 1.7 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit TRAPP PF04051.16 KKA03887.1 - 5.6e-22 78.0 0.1 7.7e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RTA1 PF04479.13 KKA03888.1 - 1.7e-42 145.4 5.1 1.7e-42 145.4 5.1 1.9 1 1 1 2 2 2 1 RTA1 like protein PetM PF08041.11 KKA03888.1 - 0.083 12.5 0.6 0.3 10.7 0.6 2.0 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 XRN_N PF03159.18 KKA03889.1 - 3.5e-93 311.5 0.0 8.1e-93 310.3 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KKA03889.1 - 2.2e-78 264.2 12.8 9.5e-78 262.1 12.8 2.0 1 1 0 1 1 1 1 Xrn1 helical domain Nro1 PF12753.7 KKA03890.1 - 5.1e-23 81.7 23.5 3.5e-22 78.9 23.5 2.0 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 RTA1 PF04479.13 KKA03891.1 - 1e-40 139.5 7.4 1e-40 139.5 7.4 1.9 1 1 1 2 2 2 1 RTA1 like protein TP_methylase PF00590.20 KKA03892.1 - 1.2e-36 126.6 0.0 1.7e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DASH_Dad4 PF08650.10 KKA03892.1 - 1.2 9.2 6.9 0.69 9.9 0.6 3.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 zf-AN1 PF01428.16 KKA03893.1 - 1.8e-08 34.4 12.7 2.6e-08 33.9 12.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger C5HCH PF17982.1 KKA03893.1 - 0.021 14.9 4.6 0.021 14.9 4.6 1.7 1 1 1 2 2 2 0 NSD Cys-His rich domain RNase_J_C PF17770.1 KKA03893.1 - 9.6 7.3 6.6 2.6 9.2 1.3 2.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain CIAPIN1 PF05093.13 KKA03894.1 - 2.5e-37 127.4 3.2 2.5e-37 127.4 3.2 1.6 1 1 1 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KKA03894.1 - 3.5e-07 30.5 0.5 6.3e-07 29.7 0.5 1.4 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Flavoprotein PF02441.19 KKA03895.1 - 5.6e-48 162.7 0.8 9.1e-48 162.0 0.1 1.7 2 0 0 2 2 2 1 Flavoprotein Nse4-Nse3_bdg PF15412.6 KKA03895.1 - 1 9.5 16.6 0.38 10.9 3.8 2.8 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE RsbU_N PF08673.10 KKA03895.1 - 5.6 7.1 6.2 7.7 6.7 0.9 2.6 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain PIN_6 PF17146.4 KKA03896.1 - 9.2e-28 96.6 0.3 3.2e-27 94.8 0.0 2.1 2 1 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KKA03896.1 - 6.9e-21 74.2 2.4 6.9e-21 74.2 2.4 1.9 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like DUF4172 PF13776.6 KKA03896.1 - 0.2 12.0 0.7 0.81 10.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Presenilin PF01080.17 KKA03896.1 - 8.2 5.1 8.1 15 4.2 8.1 1.4 1 0 0 1 1 1 0 Presenilin SGS PF05002.15 KKA03897.1 - 1.8e-24 85.6 3.2 1.8e-24 85.6 3.2 2.0 2 0 0 2 2 2 1 SGS domain MAP65_ASE1 PF03999.12 KKA03898.1 - 3.2e-64 217.7 45.2 3.2e-64 217.7 45.2 2.1 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Kri1 PF05178.12 KKA03898.1 - 0.069 13.7 5.8 0.72 10.4 5.8 2.9 1 1 0 1 1 1 0 KRI1-like family PKHD_C PF18331.1 KKA03898.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Glutaredoxin2_C PF04399.13 KKA03898.1 - 3 7.7 7.7 0.93 9.3 0.5 3.4 3 1 1 4 4 4 0 Glutaredoxin 2, C terminal domain DUF676 PF05057.14 KKA03899.1 - 9.4e-43 146.2 1.1 1.7e-42 145.4 1.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KKA03899.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KKA03899.1 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.18 KKA03899.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) SMI1_KNR4 PF09346.10 KKA03900.1 - 0.0043 17.4 0.2 0.0099 16.3 0.2 1.5 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) NRBF2 PF08961.10 KKA03900.1 - 0.017 14.7 2.0 0.028 14.1 2.0 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator MCC-bdg_PDZ PF10506.9 KKA03900.1 - 0.034 14.2 0.4 0.091 12.8 0.4 1.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Tho2 PF11262.8 KKA03900.1 - 0.051 12.8 3.6 0.087 12.0 3.6 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.9 KKA03900.1 - 0.051 12.7 0.5 0.087 11.9 0.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 KKA03900.1 - 0.26 11.4 6.2 0.17 12.0 3.9 1.8 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 KKA03900.1 - 3.1 8.5 9.8 0.94 10.2 6.2 1.9 2 0 0 2 2 2 0 Initiation control protein YabA STAT2_C PF12188.8 KKA03900.1 - 6.3 6.8 7.3 5.1 7.1 3.1 2.5 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal Pkinase PF00069.25 KKA03901.1 - 5.2e-57 193.2 0.0 6.2e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKA03901.1 - 4.8e-18 65.4 0.0 7.1e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKA03901.1 - 6.2e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKA03901.1 - 0.0023 17.3 0.0 0.0061 15.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KKA03901.1 - 0.0029 17.2 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase putAbiC PF16872.5 KKA03901.1 - 0.0068 17.1 1.0 0.6 10.8 0.1 3.2 3 0 0 3 3 3 1 Putative phage abortive infection protein FTA2 PF13095.6 KKA03901.1 - 0.039 13.6 0.1 0.12 12.0 0.0 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RE_LlaMI PF09562.10 KKA03901.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 LlaMI restriction endonuclease Ribosomal_L3 PF00297.22 KKA03902.1 - 1.9e-188 626.0 11.6 2.2e-188 625.8 11.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PHD PF00628.29 KKA03904.1 - 8.1e-07 28.8 9.4 1.4e-06 28.1 9.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKA03904.1 - 0.04 13.5 2.8 0.074 12.6 2.8 1.4 1 0 0 1 1 1 0 PHD-finger RabGAP-TBC PF00566.18 KKA03905.1 - 1.7e-47 161.9 10.6 1.7e-47 161.9 10.6 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4980 PF16352.5 KKA03905.1 - 0.065 13.2 0.8 7.6 6.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) Lactamase_B_4 PF13691.6 KKA03906.1 - 2e-06 27.4 0.1 8.8e-06 25.3 0.1 2.2 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KKA03906.1 - 2.2e-06 27.3 0.0 0.059 12.9 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKA03906.1 - 0.15 12.1 0.4 0.31 11.0 0.4 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Vps5 PF09325.10 KKA03907.1 - 2.7e-33 115.5 14.5 3e-32 112.0 14.5 2.4 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KKA03907.1 - 1.3e-17 63.8 0.2 4.7e-17 62.0 0.2 2.1 1 0 0 1 1 1 1 PX domain zf-C2H2_aberr PF17017.5 KKA03907.1 - 0.0034 17.6 1.2 0.0034 17.6 1.2 2.9 3 0 0 3 3 3 1 Aberrant zinc-finger P-mevalo_kinase PF04275.14 KKA03907.1 - 0.021 14.8 7.6 14 5.7 0.1 4.0 4 0 0 4 4 4 0 Phosphomevalonate kinase YqzH PF14164.6 KKA03907.1 - 0.021 14.9 1.3 0.19 11.8 0.0 3.3 3 0 0 3 3 3 0 YqzH-like protein GP11 PF08677.10 KKA03907.1 - 0.14 11.6 0.7 0.49 9.8 0.3 1.9 2 0 0 2 2 2 0 GP11 baseplate wedge protein Thymidylat_synt PF00303.19 KKA03908.1 - 3.7e-117 390.2 0.0 4.2e-117 390.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase THF_DHG_CYH PF00763.23 KKA03910.1 - 4.3e-26 91.5 0.0 1.3e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KKA03910.1 - 8.4e-16 57.7 0.0 1.4e-13 50.4 0.0 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMN_red PF03358.15 KKA03910.1 - 0.2 11.4 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 NADPH-dependent FMN reductase FTP PF07504.13 KKA03910.1 - 0.42 10.5 1.5 0.58 10.0 0.2 1.9 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif GST_N_2 PF13409.6 KKA03911.1 - 1.1e-17 64.0 0.0 1.6e-16 60.3 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKA03911.1 - 2.6e-11 43.4 0.0 5.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKA03911.1 - 6.1e-05 23.2 0.1 0.00013 22.1 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKA03911.1 - 0.0018 18.4 0.4 0.0039 17.3 0.4 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKA03911.1 - 0.0085 16.5 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Lentivirus_VIF PF05851.11 KKA03911.1 - 0.15 11.0 0.6 0.26 10.1 0.3 1.4 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) SOAR PF16533.5 KKA03912.1 - 0.041 13.8 1.1 0.041 13.8 1.1 2.4 2 1 0 2 2 2 0 STIM1 Orai1-activating region Alg6_Alg8 PF03155.15 KKA03914.1 - 2.2e-66 224.8 35.9 3.2e-66 224.3 35.9 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SANT_DAMP1_like PF16282.5 KKA03915.1 - 3.1e-06 27.3 0.7 3.1e-06 27.3 0.7 2.7 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 DUF4757 PF15949.5 KKA03915.1 - 0.017 15.6 3.1 0.017 15.6 3.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4757) ARTD15_N PF18084.1 KKA03916.1 - 0.0019 18.4 0.1 0.0093 16.2 0.1 2.2 1 1 0 1 1 1 1 ARTD15 N-terminal domain GOLGA2L5 PF15070.6 KKA03917.1 - 0.0061 15.3 0.8 0.0096 14.6 0.8 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Aldo_ket_red PF00248.21 KKA03918.1 - 9.9e-41 139.8 0.0 6.9e-39 133.8 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Fae PF08714.11 KKA03918.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) STT3 PF02516.14 KKA03919.1 - 3.2e-144 481.5 40.7 1.8e-140 469.1 38.6 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit CH PF00307.31 KKA03920.1 - 1.1 9.5 7.3 0.15 12.3 0.6 2.6 2 1 1 3 3 3 0 Calponin homology (CH) domain Haspin_kinase PF12330.8 KKA03921.1 - 1.3e-10 40.8 34.1 1.3e-10 40.8 34.1 4.2 2 2 2 4 4 4 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 KKA03921.1 - 0.0089 15.3 0.1 0.024 14.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKA03921.1 - 0.0094 15.3 0.0 0.029 13.7 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKA03921.1 - 0.012 15.0 1.7 0.012 15.0 1.7 2.0 2 1 1 3 3 3 0 Protein kinase domain APH PF01636.23 KKA03921.1 - 0.11 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CHD5 PF04420.14 KKA03922.1 - 9.6e-26 90.5 4.5 1.1e-25 90.4 4.3 1.3 1 1 0 1 1 1 1 CHD5-like protein Occludin_ELL PF07303.13 KKA03922.1 - 0.03 15.0 1.0 0.08 13.7 0.5 1.8 1 1 0 1 1 1 0 Occludin homology domain CK_II_beta PF01214.18 KKA03923.1 - 1.3e-46 158.7 1.4 3e-46 157.5 1.4 1.6 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.13 KKA03924.1 - 2.5e-07 31.1 3.8 2.5e-07 31.1 3.8 2.0 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain FYVE PF01363.21 KKA03925.1 - 1.1e-16 60.7 3.6 2.3e-16 59.7 3.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-C2HC5 PF06221.13 KKA03925.1 - 0.13 12.2 2.2 0.3 11.1 2.2 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-AN1 PF01428.16 KKA03925.1 - 2.4 8.4 12.5 5.6 7.2 12.5 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger ATE_C PF04377.15 KKA03926.1 - 2.9e-42 144.5 2.7 5.2e-42 143.6 1.4 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KKA03926.1 - 1.5e-21 76.5 4.1 4.2e-21 75.1 4.1 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Aminotran_1_2 PF00155.21 KKA03928.1 - 7e-19 68.2 0.0 1.1e-18 67.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II SNF2_N PF00176.23 KKA03929.1 - 4.5e-58 196.6 1.4 9.1e-58 195.6 1.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKA03929.1 - 3.6e-20 72.3 0.2 1.4e-19 70.5 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA03929.1 - 1.8e-09 37.6 0.0 4.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWIRM PF04433.17 KKA03930.1 - 1.3e-23 83.2 3.3 1.3e-23 83.2 3.3 2.5 2 1 1 3 3 3 1 SWIRM domain ZZ PF00569.17 KKA03930.1 - 7.3e-05 22.5 3.2 0.00014 21.6 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KKA03930.1 - 0.0001 22.4 0.2 0.00031 20.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKA03930.1 - 0.00032 20.9 2.2 0.00061 20.0 0.1 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF4428 PF14471.6 KKA03930.1 - 0.018 14.9 0.5 0.075 13.0 0.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Transcrip_reg PF01709.20 KKA03931.1 - 3.5e-35 121.5 9.8 4.1e-35 121.3 9.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF3905 PF13045.6 KKA03931.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) SRP54_N PF02881.19 KKA03931.1 - 0.2 11.9 7.0 0.087 13.1 1.8 2.8 2 1 1 3 3 3 0 SRP54-type protein, helical bundle domain Mito_carr PF00153.27 KKA03932.1 - 6e-68 224.8 2.3 2.8e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KKA03933.1 - 4.4e-20 71.9 34.1 7.2e-20 71.2 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 KKA03933.1 - 1.5 9.1 14.6 3.9 7.8 3.5 3.8 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) PUCC PF03209.15 KKA03933.1 - 6.4 5.7 13.8 0.015 14.4 0.9 2.5 3 0 0 3 3 3 0 PUCC protein Pep1_7 PF17232.2 KKA03934.1 - 0.87 10.1 4.6 0.87 10.1 0.1 2.5 2 0 0 2 2 2 0 Elicitor peptide 1-7 Tnp_P_element_C PF12596.8 KKA03934.1 - 2 9.0 10.2 5.2 7.7 10.2 1.7 1 0 0 1 1 1 0 87kDa Transposase Zn_clus PF00172.18 KKA03935.1 - 7.1e-05 22.9 13.5 0.0002 21.4 13.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KKA03936.1 - 1.3e-06 28.4 8.4 2.6e-06 27.4 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_F PF01990.17 KKA03937.1 - 1.8e-29 101.9 0.1 2.4e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 KKA03937.1 - 0.00087 19.1 0.1 0.0011 18.8 0.1 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 PIN_8 PF18476.1 KKA03937.1 - 0.027 14.4 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 PIN like domain fn3_2 PF16893.5 KKA03938.1 - 3e-15 56.1 2.2 4.4e-13 49.2 2.2 2.7 1 1 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KKA03938.1 - 1.7e-13 50.3 0.1 3e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KKA03938.1 - 2.2e-07 31.2 0.0 9.2e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKA03938.1 - 0.0048 17.3 0.0 0.024 15.0 0.0 2.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KKA03938.1 - 0.0056 16.7 0.0 0.024 14.7 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKA03938.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain LIG3_BRCT PF16759.5 KKA03938.1 - 1.2 9.5 3.9 1.3 9.4 0.0 2.7 2 1 0 2 2 2 0 DNA ligase 3 BRCT domain PX PF00787.24 KKA03939.1 - 2.2e-13 50.1 0.2 3.5e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 PX domain Pyr_redox_2 PF07992.14 KKA03940.1 - 3e-48 164.6 0.0 3.6e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKA03940.1 - 3.9e-18 65.8 0.2 9.1e-17 61.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKA03940.1 - 2e-15 56.8 1.2 2.7e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKA03940.1 - 0.006 17.0 0.1 0.1 13.1 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KKA03940.1 - 0.011 15.0 0.2 0.036 13.3 0.1 1.8 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 KKA03940.1 - 0.047 12.8 0.0 3.4 6.7 0.0 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) CEP1-DNA_bind PF09287.10 KKA03940.1 - 0.092 12.4 0.1 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 CEP-1, DNA binding FAD_binding_2 PF00890.24 KKA03940.1 - 0.25 10.4 1.2 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Septin PF00735.18 KKA03941.1 - 1.1e-101 339.8 4.3 1.9e-101 339.1 4.3 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KKA03941.1 - 9.7e-10 38.3 0.2 1.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKA03941.1 - 1.4e-07 31.5 0.0 4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.12 KKA03941.1 - 0.00037 20.0 0.1 0.00078 19.0 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein RsgA_GTPase PF03193.16 KKA03941.1 - 0.00067 19.6 2.8 0.0013 18.7 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase Roc PF08477.13 KKA03941.1 - 0.0011 19.2 0.2 0.006 16.8 0.2 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KKA03941.1 - 0.0016 17.6 0.0 0.0042 16.2 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KKA03941.1 - 0.0047 17.4 0.4 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KKA03941.1 - 0.0067 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKA03941.1 - 0.0073 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKA03941.1 - 0.0083 16.4 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KKA03941.1 - 0.01 15.9 5.1 1.9 8.5 0.1 3.4 2 1 1 3 3 3 0 Dynamin family Sigma54_activat PF00158.26 KKA03941.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 KKA03941.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 KKA03941.1 - 0.025 14.3 0.1 0.52 10.0 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KKA03941.1 - 0.029 13.9 0.5 0.062 12.8 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KKA03941.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ras PF00071.22 KKA03941.1 - 0.066 12.8 0.3 0.31 10.6 0.3 2.1 1 1 0 1 1 1 0 Ras family NB-ARC PF00931.22 KKA03941.1 - 0.087 12.0 1.4 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KKA03941.1 - 0.11 12.7 0.1 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKA03941.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KKA03941.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Glycos_transf_3 PF00591.21 KKA03942.1 - 1.5e-63 214.8 0.0 2.8e-63 213.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KKA03942.1 - 0.0027 17.5 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Spc7 PF08317.11 KKA03943.1 - 5.5e-05 22.2 37.3 0.00036 19.5 20.6 6.1 1 1 5 6 6 6 3 Spc7 kinetochore protein SOGA PF11365.8 KKA03943.1 - 0.002 19.2 2.6 0.002 19.2 2.6 10.5 1 1 11 12 12 12 5 Protein SOGA Peptidase_M18 PF02127.15 KKA03944.1 - 4e-147 490.5 0.2 4.5e-147 490.3 0.2 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KKA03944.1 - 1.5e-06 27.4 0.0 0.0038 16.3 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase AT_hook PF02178.19 KKA03945.1 - 0.011 15.5 1.6 0.034 14.0 1.6 1.9 1 0 0 1 1 1 0 AT hook motif ThiF PF00899.21 KKA03946.1 - 6.5e-53 179.6 0.0 1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KKA03946.1 - 3.5e-07 30.7 0.0 8.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain PglD_N PF17836.1 KKA03946.1 - 0.0056 17.3 0.5 0.018 15.7 0.4 2.0 1 1 0 1 1 1 1 PglD N-terminal domain Shikimate_DH PF01488.20 KKA03946.1 - 0.02 14.9 0.0 0.077 13.0 0.0 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KKA03946.1 - 0.36 10.4 1.6 2.5 7.6 1.6 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EMP24_GP25L PF01105.24 KKA03947.1 - 5.5e-28 98.1 3.0 8.2e-27 94.3 3.0 2.0 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BCIP PF13862.6 KKA03948.1 - 2.1e-34 119.1 6.5 3.2e-34 118.5 6.5 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Myb_DNA-bind_6 PF13921.6 KKA03949.1 - 1.1e-08 35.1 1.1 5.9e-08 32.8 0.2 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KKA03949.1 - 5.7e-05 23.4 0.2 5.7e-05 23.4 0.2 3.8 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KKA03949.1 - 0.00012 22.2 0.0 0.00041 20.5 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain VHS PF00790.19 KKA03950.1 - 1.1e-37 129.0 1.7 1.8e-37 128.3 0.1 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KKA03950.1 - 1.4e-11 44.5 4.8 2.1e-11 44.0 1.2 3.2 4 0 0 4 4 4 1 GAT domain Alpha_adaptinC2 PF02883.20 KKA03950.1 - 1.1e-08 35.4 0.6 1.1e-08 35.4 0.6 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KKA03950.1 - 1.4e-07 31.0 0.2 4.2e-07 29.5 0.2 1.9 1 0 0 1 1 1 1 GGA N-GAT domain RNA_pol_Rpb1_5 PF04998.17 KKA03951.1 - 1e-82 277.6 1.8 1.9e-82 276.7 1.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KKA03951.1 - 3.2e-77 259.9 3.0 3.7e-77 259.7 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KKA03951.1 - 4.4e-73 245.0 0.1 1.4e-72 243.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKA03951.1 - 9.7e-40 136.1 0.2 4.3e-39 134.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKA03951.1 - 1.1e-30 105.8 0.0 4.5e-30 103.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 VHS PF00790.19 KKA03951.1 - 0.028 14.3 1.0 0.074 12.9 1.0 1.7 1 0 0 1 1 1 0 VHS domain DUF1411 PF07199.11 KKA03951.1 - 0.067 12.8 1.5 0.13 11.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) PRAI PF00697.22 KKA03951.1 - 0.17 11.7 0.9 0.35 10.6 0.9 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Rad60-SLD PF11976.8 KKA03952.1 - 2.1e-11 43.5 1.6 1.9e-09 37.2 1.1 3.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like AAA PF00004.29 KKA03953.1 - 4.3e-41 140.4 0.0 9.5e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKA03953.1 - 8e-19 67.3 0.1 1.8e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKA03953.1 - 6.2e-09 35.5 0.1 1.5e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KKA03953.1 - 7.1e-06 26.2 0.2 6.6e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKA03953.1 - 7.4e-06 26.4 0.6 0.011 16.2 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KKA03953.1 - 0.0002 21.7 0.2 0.062 13.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KKA03953.1 - 0.00039 20.4 0.1 0.0032 17.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKA03953.1 - 0.00072 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KKA03953.1 - 0.0048 16.1 0.0 0.013 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 KKA03953.1 - 0.0075 15.7 0.1 0.053 13.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 KKA03953.1 - 0.009 16.2 0.1 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKA03953.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKA03953.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3807 PF12720.7 KKA03953.1 - 0.039 14.2 1.3 0.078 13.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_24 PF13479.6 KKA03953.1 - 0.053 13.2 0.1 0.27 10.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKA03953.1 - 0.054 13.3 2.3 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKA03953.1 - 0.099 13.0 0.0 0.41 11.1 0.0 2.1 2 1 1 3 3 2 0 RNA helicase ATPase PF06745.13 KKA03953.1 - 0.18 11.1 1.7 0.47 9.7 0.0 2.4 2 1 0 2 2 2 0 KaiC CLZ PF16526.5 KKA03953.1 - 0.2 12.1 4.0 0.78 10.1 4.0 2.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 KKA03953.1 - 0.66 10.0 8.6 0.41 10.7 6.3 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NUC153 PF08159.12 KKA03954.1 - 4e-13 48.9 2.2 4e-13 48.9 2.2 2.9 3 0 0 3 3 3 1 NUC153 domain RIO1 PF01163.22 KKA03955.1 - 5.6e-64 215.2 2.9 5.6e-64 215.2 2.9 2.1 2 0 0 2 2 2 1 RIO1 family CDC45 PF02724.14 KKA03955.1 - 0.95 7.7 22.7 1.3 7.3 22.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KKA03955.1 - 2.5 7.7 18.8 3.7 7.2 18.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Profilin PF00235.19 KKA03957.1 - 2e-43 147.7 0.1 2.2e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.13 KKA03958.1 - 3e-36 124.7 0.1 3e-36 124.7 0.1 3.0 3 2 1 4 4 4 1 Leo1-like protein Glyco_hydro_18 PF00704.28 KKA03959.1 - 1.7e-65 221.8 8.4 2.2e-65 221.4 8.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Thioredoxin_11 PF18078.1 KKA03959.1 - 2.1 8.5 7.1 5.9 7.0 0.1 3.9 4 0 0 4 4 4 0 Thioredoxin-like SNTX domain GPP34 PF05719.11 KKA03960.1 - 3.2e-48 164.5 0.0 3.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GAT PF03127.14 KKA03960.1 - 0.085 13.2 1.3 0.33 11.3 0.3 2.3 2 0 0 2 2 2 0 GAT domain UCH PF00443.29 KKA03961.1 - 3.9e-42 144.5 8.5 4.3e-42 144.4 6.4 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KKA03961.1 - 1.1e-07 31.6 1.9 0.0089 15.9 0.0 4.1 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KKA03961.1 - 0.0002 21.1 10.6 0.03 13.9 0.5 3.0 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Sigma54_AID PF00309.20 KKA03961.1 - 2.2 8.2 5.6 12 5.8 0.2 3.0 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) EF-hand_7 PF13499.6 KKA03962.1 - 6e-16 58.6 10.2 2.7e-09 37.3 1.6 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KKA03962.1 - 1.3e-14 52.5 14.4 1.3e-05 24.4 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KKA03962.1 - 1.2e-13 49.8 10.7 8.6e-05 22.2 0.0 5.3 4 2 2 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 KKA03962.1 - 6.6e-05 22.7 12.2 0.0023 17.8 1.0 4.0 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KKA03962.1 - 0.00013 21.3 8.4 0.0025 17.2 0.1 3.9 4 0 0 4 4 4 1 EF hand EF-hand_10 PF14788.6 KKA03962.1 - 0.11 12.4 3.4 13 5.8 0.2 3.3 4 0 0 4 4 4 0 EF hand DUF3150 PF11348.8 KKA03962.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) SPARC_Ca_bdg PF10591.9 KKA03962.1 - 0.15 12.4 4.6 4.7 7.6 0.2 3.3 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KKA03962.1 - 0.94 9.5 4.6 12 5.9 0.3 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand COQ7 PF03232.13 KKA03963.1 - 1.5e-71 239.7 0.1 2e-71 239.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KKA03963.1 - 0.012 16.0 0.1 0.077 13.4 0.0 2.1 2 0 0 2 2 2 0 Rubrerythrin YTH PF04146.15 KKA03964.1 - 1.8e-22 80.1 4.4 7.4e-22 78.0 4.4 1.9 1 1 0 1 1 1 1 YT521-B-like domain BCS1_N PF08740.11 KKA03965.1 - 1.5e-48 165.3 0.0 2.1e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KKA03965.1 - 1.1e-21 77.7 0.0 1.9e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKA03965.1 - 0.001 19.5 0.0 0.0033 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KKA03965.1 - 0.0022 18.1 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKA03965.1 - 0.0053 17.3 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKA03965.1 - 0.0066 16.5 0.1 0.029 14.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KKA03965.1 - 0.014 15.2 0.0 0.088 12.5 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KKA03965.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KKA03965.1 - 0.022 14.5 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KKA03965.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 KKA03965.1 - 0.023 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKA03965.1 - 0.024 14.1 0.0 0.07 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KKA03965.1 - 0.034 14.7 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KKA03965.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 KKA03965.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KKA03965.1 - 0.056 13.7 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KKA03965.1 - 0.07 13.1 0.0 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Gram_pos_anchor PF00746.21 KKA03965.1 - 0.08 12.9 1.2 0.17 11.8 1.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif AAA_28 PF13521.6 KKA03965.1 - 0.091 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKA03965.1 - 0.092 13.1 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.6 KKA03965.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KKA03965.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKA03965.1 - 0.17 11.6 0.0 0.78 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Lipase_GDSL_2 PF13472.6 KKA03966.1 - 2.7e-14 53.9 0.0 4.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKA03966.1 - 8.2e-12 45.5 0.3 1.2e-11 44.9 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HMG_box PF00505.19 KKA03966.1 - 0.015 15.7 0.9 0.15 12.5 0.0 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box Pyr_redox_2 PF07992.14 KKA03967.1 - 9.5e-05 21.8 0.0 0.027 13.7 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKA03967.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKA03967.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_60s PF00428.19 KKA03968.1 - 7.3e-24 84.2 11.4 8.3e-24 84.0 11.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KKA03968.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Mito_carr PF00153.27 KKA03969.1 - 1.4e-65 217.2 2.8 2.4e-21 75.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KKA03970.1 - 2.2e-43 146.1 4.2 6.9e-17 61.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KKA03970.1 - 0.0012 19.0 2.4 0.086 13.1 0.3 2.9 3 0 0 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Phage_Coat_B PF05356.11 KKA03970.1 - 0.056 13.3 0.3 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Phage Coat protein B GPHR_N PF12537.8 KKA03970.1 - 0.071 13.2 2.9 1 9.5 0.4 3.0 3 1 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal FERM_M PF00373.18 KKA03970.1 - 0.08 13.3 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 FERM central domain Choline_kin_N PF04428.14 KKA03970.1 - 0.098 12.3 0.3 0.25 11.0 0.3 1.7 1 0 0 1 1 1 0 Choline kinase N terminus AIRC PF00731.20 KKA03971.1 - 3.9e-61 205.0 1.3 7.1e-61 204.1 1.3 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KKA03971.1 - 2.9e-59 199.5 0.0 5.5e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KKA03971.1 - 1.1e-15 57.0 0.0 2.4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KKA03971.1 - 3.9e-06 26.5 0.1 2.1e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KKA03971.1 - 2e-05 24.2 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 KKA03971.1 - 0.00024 20.5 0.0 0.00061 19.2 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.11 KKA03971.1 - 0.019 14.5 1.3 9.1 5.8 0.0 3.2 2 2 1 3 3 3 0 Propionate catabolism activator AlaDh_PNT_C PF01262.21 KKA03971.1 - 0.022 14.1 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 KKA03971.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Zn_clus PF00172.18 KKA03972.1 - 1.7e-07 31.3 3.6 2.7e-07 30.6 3.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.27 KKA03973.1 - 1.3e-21 77.0 0.9 2.3e-20 73.0 0.9 2.8 1 1 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KKA03973.1 - 1.7e-14 53.8 25.3 9e-09 35.4 6.8 2.5 2 0 0 2 2 2 2 LIM domain zf-C3HC4_3 PF13920.6 KKA03973.1 - 0.64 9.9 19.7 0.45 10.4 4.0 3.4 2 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SWIRM-assoc_1 PF16495.5 KKA03973.1 - 0.74 9.8 3.4 3.2 7.8 3.4 2.1 1 0 0 1 1 1 0 SWIRM-associated region 1 PX PF00787.24 KKA03974.1 - 0.0026 17.7 1.8 0.013 15.5 1.8 2.3 1 1 0 1 1 1 1 PX domain Tiam_CC_Ex PF18385.1 KKA03974.1 - 0.057 13.8 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain GTP_EFTU PF00009.27 KKA03975.1 - 4.6e-66 222.1 0.4 6.6e-66 221.6 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKA03975.1 - 1.6e-32 111.8 0.1 9.5e-32 109.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KKA03975.1 - 1.5e-21 76.2 0.0 4.4e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KKA03975.1 - 8.4e-14 51.4 0.0 3.1e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KKA03975.1 - 1.3e-13 51.1 0.2 6.2e-13 48.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKA03975.1 - 0.00025 21.1 0.2 0.00051 20.1 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAST_1 PF06743.15 KKA03975.1 - 0.1 12.6 0.0 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 ERCC4 PF02732.15 KKA03976.1 - 3.5e-25 89.0 0.6 3.5e-25 89.0 0.6 2.4 4 0 0 4 4 4 1 ERCC4 domain MRP-L20 PF12824.7 KKA03978.1 - 0.00015 22.0 0.3 0.00029 21.1 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MFS_1 PF07690.16 KKA03979.1 - 1.1e-36 126.5 16.0 1.8e-36 125.8 13.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKA03979.1 - 1.1e-15 57.4 3.3 1.1e-15 57.4 3.3 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KKA03979.1 - 9.7e-07 27.7 4.1 9.7e-07 27.7 4.1 3.7 3 2 1 4 4 4 2 MFS/sugar transport protein TFIIE_alpha PF02002.17 KKA03980.1 - 2.6e-27 94.7 4.6 6.8e-26 90.2 0.0 3.2 3 1 0 3 3 3 2 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KKA03980.1 - 1.3e-06 27.8 0.3 4.2e-06 26.2 0.3 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_IclR PF09339.10 KKA03980.1 - 0.058 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain ThiF PF00899.21 KKA03981.1 - 2.1e-41 141.9 0.0 3.2e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KKA03981.1 - 0.0019 18.5 0.1 0.0046 17.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain CagA PF03507.13 KKA03981.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 CagA exotoxin Mito_carr PF00153.27 KKA03982.1 - 1.5e-59 197.9 3.7 6.9e-20 70.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2370 PF10176.9 KKA03983.1 - 1.9e-61 207.6 1.5 3.1e-51 174.2 0.0 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) SVM_signal PF12113.8 KKA03983.1 - 0.4 10.6 4.8 1 9.3 1.2 2.6 2 0 0 2 2 2 0 SVM protein signal sequence SNF5 PF04855.12 KKA03984.1 - 2e-23 83.5 3.0 1.7e-14 54.2 0.1 3.5 4 1 1 5 5 5 2 SNF5 / SMARCB1 / INI1 DUF1993 PF09351.10 KKA03984.1 - 0.41 10.8 3.0 0.95 9.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) ArgJ PF01960.18 KKA03985.1 - 1.8e-140 468.0 5.1 2.1e-140 467.8 5.1 1.0 1 0 0 1 1 1 1 ArgJ family HA2 PF04408.23 KKA03986.1 - 2.2e-19 69.7 0.4 2.2e-19 69.7 0.4 2.3 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKA03986.1 - 8.1e-15 55.0 0.0 4.8e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKA03986.1 - 9.6e-12 45.2 0.2 5.4e-11 42.8 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKA03986.1 - 6.6e-09 35.8 0.1 1.6e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKA03986.1 - 1.7e-05 25.1 3.8 0.0014 18.9 0.7 3.0 1 1 1 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KKA03986.1 - 0.0021 17.9 0.2 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 Helicase ABC_tran PF00005.27 KKA03986.1 - 0.0031 18.0 0.7 0.029 14.9 0.0 2.8 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 KKA03986.1 - 0.0033 17.3 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_19 PF13245.6 KKA03986.1 - 0.0045 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KKA03986.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 KKA03986.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKA03986.1 - 0.0089 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase PF06745.13 KKA03986.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC MeaB PF03308.16 KKA03986.1 - 0.031 13.3 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2703 PF10865.8 KKA03986.1 - 0.049 13.8 0.5 9.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) PhoH PF02562.16 KKA03986.1 - 0.07 12.6 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein FKBP_N PF01346.18 KKA03986.1 - 1.3 10.0 9.1 0.17 12.9 0.4 2.8 3 1 0 3 3 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2408 PF10303.9 KKA03986.1 - 4.8 7.8 7.3 1.1 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AAA PF00004.29 KKA03987.1 - 3.4e-38 131.0 0.0 5.8e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKA03987.1 - 1.3e-07 31.3 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKA03987.1 - 4.2e-05 24.0 0.1 0.002 18.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KKA03987.1 - 0.00011 21.5 0.0 0.00036 19.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKA03987.1 - 0.00017 21.9 0.2 0.03 14.6 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKA03987.1 - 0.00022 21.3 0.1 0.0023 17.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKA03987.1 - 0.00025 20.9 0.0 0.00073 19.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KKA03987.1 - 0.0004 19.9 0.0 0.0015 18.0 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 KKA03987.1 - 0.0036 17.4 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KKA03987.1 - 0.0058 16.4 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KKA03987.1 - 0.0062 15.8 0.2 0.031 13.5 0.1 2.1 2 1 0 2 2 2 1 TIP49 P-loop domain Rad17 PF03215.15 KKA03987.1 - 0.01 15.7 0.1 0.91 9.4 0.0 2.5 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KKA03987.1 - 0.014 15.1 0.2 0.042 13.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKA03987.1 - 0.015 15.3 0.0 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKA03987.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKA03987.1 - 0.018 15.6 0.1 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKA03987.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KKA03987.1 - 0.021 14.2 0.0 7.1 6.0 0.0 2.7 2 1 0 3 3 3 0 Bacterial TniB protein ATPase PF06745.13 KKA03987.1 - 0.024 14.0 0.3 0.6 9.4 0.0 2.6 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 KKA03987.1 - 0.048 13.2 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKA03987.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KKA03987.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 KKA03987.1 - 0.14 11.9 0.1 0.43 10.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKA03987.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IPPT PF01715.17 KKA03987.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 IPP transferase NEMO PF11577.8 KKA03987.1 - 6.9 6.8 5.7 34 4.5 0.3 2.7 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO V-ATPase_C PF03223.15 KKA03989.1 - 1.6e-112 376.6 6.3 1.8e-112 376.4 6.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Ku_PK_bind PF08785.11 KKA03989.1 - 0.0017 18.5 0.0 0.028 14.6 0.0 2.6 2 0 0 2 2 2 1 Ku C terminal domain like EF1G PF00647.19 KKA03990.1 - 2e-44 150.0 0.2 1e-43 147.8 0.1 2.1 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKA03990.1 - 1.2e-07 31.9 1.8 1.2e-07 31.8 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKA03990.1 - 2.1e-05 24.8 0.2 5.5e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKA03990.1 - 7.2e-05 22.7 0.2 0.00016 21.6 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKA03990.1 - 0.00012 22.2 0.2 0.00042 20.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 KKA03990.1 - 0.0097 16.3 0.3 0.016 15.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 EF1G PF00647.19 KKA03991.1 - 1.8e-44 150.2 0.2 9.2e-44 147.9 0.1 2.1 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKA03991.1 - 7e-09 35.8 0.2 7e-09 35.8 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKA03991.1 - 2.5e-06 27.4 4.6 4.4e-06 26.6 1.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKA03991.1 - 0.00011 22.5 0.0 0.00028 21.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKA03991.1 - 0.0024 18.2 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKA03991.1 - 0.0029 17.7 0.1 0.009 16.2 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF1G PF00647.19 KKA03992.1 - 2.1e-44 149.9 0.2 9.2e-44 147.9 0.1 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKA03992.1 - 1.3e-08 34.9 0.1 1.3e-08 34.9 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKA03992.1 - 0.00025 21.0 0.4 0.00069 19.6 0.4 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKA03992.1 - 0.0025 18.0 0.1 0.0075 16.4 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKA03992.1 - 0.071 13.5 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Hanseniaspora_uvarum-Huva2.0/GCA_000968475.1_Huva2.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Hanseniaspora_uvarum-Huva2.0/GCA_000968475.1_Huva2.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Hanseniaspora_uvarum-Huva2.0/GCA_000968475.1_Huva2.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Hanseniaspora_uvarum-Huva2.0/GCA_000968475.1_Huva2.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 20:28:02 2019 # [ok]