# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RicinB_lectin_2 PF14200.6 KIK49676.1 - 0.00017 22.2 1.2 0.0057 17.4 1.0 2.1 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Retrotrans_gag PF03732.17 KIK49677.1 - 4.6e-08 33.2 0.0 1.1e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK49677.1 - 0.0025 17.7 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) PIF1 PF05970.14 KIK49678.1 - 0.0012 18.1 2.1 0.54 9.4 0.6 2.8 1 1 1 2 2 2 2 PIF1-like helicase Eaf7 PF07904.13 KIK49678.1 - 0.088 13.2 0.5 0.13 12.6 0.5 1.5 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 HEV_ORF1 PF02444.16 KIK49680.1 - 1.4 9.5 9.9 0.094 13.3 1.7 2.4 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) WD40 PF00400.32 KIK49683.1 - 4.3e-25 87.5 7.5 4.2e-09 36.9 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49683.1 - 1.6e-08 34.7 0.5 0.068 13.5 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK49683.1 - 0.037 13.0 0.6 1.2 8.0 0.1 2.7 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK49683.1 - 0.046 13.0 0.5 1.2 8.4 0.1 2.3 1 1 1 2 2 2 0 WD40-like domain NACHT PF05729.12 KIK49683.1 - 0.09 12.7 0.0 0.25 11.3 0.0 1.7 1 1 1 2 2 2 0 NACHT domain T2SSK PF03934.13 KIK49685.1 - 0.093 12.1 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K TPR_12 PF13424.6 KIK49686.1 - 3e-23 81.9 13.4 2.4e-09 37.3 0.6 3.8 1 1 4 5 5 5 5 Tetratricopeptide repeat SNAP PF14938.6 KIK49686.1 - 2.4e-09 37.1 1.0 0.00067 19.2 0.3 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KIK49686.1 - 1.4e-08 34.3 3.8 0.099 12.5 0.2 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK49686.1 - 3.9e-08 32.8 0.9 1.1 9.5 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK49686.1 - 0.00096 18.9 2.6 10 6.1 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2805 PF10985.8 KIK49686.1 - 0.00098 19.5 0.0 42 4.6 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2805) CobN-Mg_chel PF02514.16 KIK49686.1 - 0.0018 16.2 0.7 0.52 8.0 0.0 2.9 1 1 1 3 3 3 2 CobN/Magnesium Chelatase SHNi-TPR PF10516.9 KIK49686.1 - 0.0035 16.8 0.0 0.037 13.5 0.0 2.7 4 0 0 4 4 4 1 SHNi-TPR TPR_MalT PF17874.1 KIK49686.1 - 0.0053 16.2 6.6 0.0063 15.9 6.6 1.1 1 0 0 1 1 1 1 MalT-like TPR region ANAPC3 PF12895.7 KIK49686.1 - 0.0074 16.5 3.7 6 7.2 0.0 3.8 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Vps54_N PF10475.9 KIK49686.1 - 0.11 11.8 0.2 4.5 6.5 0.1 3.0 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex PAF-AH_p_II PF03403.13 KIK49686.1 - 0.14 10.7 0.6 20 3.5 0.0 3.2 3 1 1 4 4 4 0 Platelet-activating factor acetylhydrolase, isoform II TPR_4 PF07721.14 KIK49686.1 - 0.76 10.6 4.8 57 4.8 0.1 4.4 4 2 2 6 6 4 0 Tetratricopeptide repeat Nexin_C PF08628.12 KIK49686.1 - 0.98 10.0 5.7 33 5.1 0.1 3.8 1 1 4 5 5 5 0 Sorting nexin C terminal Ketoacyl-synt_C PF02801.22 KIK49686.1 - 2.9 7.9 5.4 14 5.8 0.2 3.2 2 2 1 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain RicinB_lectin_2 PF14200.6 KIK49687.1 - 2.1e-05 25.2 0.8 0.00076 20.2 0.7 2.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like KDZ PF18758.1 KIK49691.1 - 1.7e-54 184.8 0.1 2.8e-54 184.1 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK49692.1 - 7.4e-39 132.2 0.2 8.4e-39 132.0 0.2 1.0 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK49692.1 - 1.3e-06 28.5 0.2 1.6e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK49692.1 - 0.0083 16.0 0.2 0.01 15.7 0.2 1.1 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases PKD_channel PF08016.12 KIK49692.1 - 0.032 12.9 0.0 0.036 12.7 0.0 1.0 1 0 0 1 1 1 0 Polycystin cation channel KDZ PF18758.1 KIK49693.1 - 1e-52 179.0 0.0 1.5e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK49693.1 - 5.7e-36 122.9 0.2 5.7e-36 122.9 0.2 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK49693.1 - 1.1e-05 25.5 0.2 3.8e-05 23.8 0.2 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK49693.1 - 0.037 13.9 0.4 0.12 12.3 0.4 1.8 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Goodbye PF17109.5 KIK49695.1 - 1.1e-20 74.3 0.1 1.5e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Nterm_IS4 PF13006.7 KIK49695.1 - 0.092 13.0 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal NPV_P10 PF05531.12 KIK49695.1 - 0.098 13.1 0.2 1.8 9.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DNA_pol_phi PF04931.13 KIK49695.1 - 0.1 10.7 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi FliN_N PF16973.5 KIK49695.1 - 0.17 11.8 0.4 0.17 11.8 0.4 2.0 3 0 0 3 3 3 0 Flagellar motor switch protein FliN N-terminal DUF2457 PF10446.9 KIK49696.1 - 0.0063 15.7 0.3 0.0063 15.7 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) ApbA PF02558.16 KIK49698.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1724 PF08350.10 KIK49698.1 - 0.13 12.4 0.3 4.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) Helicase_C PF00271.31 KIK49701.1 - 1.7e-06 28.3 0.0 4.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3860 PF12976.7 KIK49701.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) adh_short PF00106.25 KIK49702.1 - 2.5e-23 82.6 0.0 2.4e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK49702.1 - 6.2e-13 48.8 0.0 1.5e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK49702.1 - 3.2e-07 30.4 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK49702.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Retrotrans_gag PF03732.17 KIK49703.1 - 5.9e-07 29.7 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK49703.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DZR PF12773.7 KIK49704.1 - 0.15 12.1 2.0 0.31 11.1 2.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KIK49704.1 - 3.7 7.7 5.5 21 5.4 1.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Mltc_N PF11873.8 KIK49705.1 - 0.0073 16.1 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Membrane-bound lytic murein transglycosylase C, N-terminal domain PHD PF00628.29 KIK49708.1 - 2 8.4 7.6 0.36 10.7 3.1 2.2 2 0 0 2 2 2 0 PHD-finger IL11 PF07400.11 KIK49709.1 - 0.15 11.7 0.3 0.28 10.8 0.3 1.4 1 0 0 1 1 1 0 Interleukin 11 DDE_3 PF13358.6 KIK49712.1 - 8.6e-08 32.1 0.1 0.00062 19.5 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease zf-B_box PF00643.24 KIK49714.1 - 0.093 12.9 5.5 0.17 12.1 5.5 1.4 1 0 0 1 1 1 0 B-box zinc finger gag_pre-integrs PF13976.6 KIK49719.1 - 1.2e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain PI3Ka PF00613.20 KIK49720.1 - 0.059 12.8 0.6 0.14 11.5 0.2 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF826 PF05696.11 KIK49722.1 - 0.096 12.8 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF826) DUF4992 PF16383.5 KIK49725.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function KRTAP PF11759.8 KIK49729.1 - 4.6 7.9 26.3 7.5 7.2 26.3 1.4 1 0 0 1 1 1 0 Keratin-associated matrix SR-25 PF10500.9 KIK49731.1 - 0.77 9.3 13.0 1.6 8.3 0.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Polyoma_lg_T_C PF06431.11 KIK49733.1 - 0.05 12.5 1.2 0.057 12.3 1.2 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus BUD22 PF09073.10 KIK49733.1 - 0.11 11.8 4.4 0.1 11.9 4.4 1.1 1 0 0 1 1 1 0 BUD22 AF-4 PF05110.13 KIK49733.1 - 1 7.3 7.1 1 7.4 7.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 KIK49733.1 - 2.5 6.3 6.3 2.7 6.2 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Cerato-platanin PF07249.12 KIK49735.1 - 2.8e-42 143.6 4.0 3.5e-42 143.3 4.0 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 KIK49735.1 - 0.075 12.6 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Cerato-platanin PF07249.12 KIK49736.1 - 1.2e-27 96.4 1.2 1.5e-27 96.1 1.2 1.1 1 0 0 1 1 1 1 Cerato-platanin LuxS PF02664.15 KIK49736.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) PIG-S PF10510.9 KIK49738.1 - 0.037 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF4404 PF14357.6 KIK49740.1 - 0.029 15.0 1.6 0.064 13.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) YtxH PF12732.7 KIK49740.1 - 0.82 10.2 3.8 0.57 10.8 1.0 2.3 2 1 0 2 2 2 0 YtxH-like protein NACHT PF05729.12 KIK49741.1 - 0.00074 19.5 1.0 0.0036 17.2 1.0 1.9 1 1 0 1 1 1 1 NACHT domain Parvo_NS1 PF01057.17 KIK49741.1 - 0.00093 18.4 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 KIK49741.1 - 0.0017 18.8 0.0 0.0022 18.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK49741.1 - 0.0064 16.9 0.1 0.015 15.7 0.1 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KIK49741.1 - 0.0078 16.4 0.2 0.0097 16.1 0.2 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIK49741.1 - 0.018 15.0 0.2 0.027 14.4 0.2 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KIK49741.1 - 0.018 15.4 0.4 0.027 14.9 0.4 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK49741.1 - 0.045 13.7 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK49741.1 - 0.05 12.8 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KIK49741.1 - 0.055 12.7 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KIK49741.1 - 0.063 13.8 0.5 0.064 13.8 0.5 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK49741.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK49741.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK49741.1 - 0.15 12.6 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KIK49741.1 - 0.15 12.4 0.4 0.25 11.7 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK49741.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIK49741.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KIK49741.1 - 0.25 11.1 0.6 0.53 10.0 0.6 1.7 1 1 0 1 1 1 0 AAA domain DUF4939 PF16297.5 KIK49743.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF4218 PF13960.6 KIK49744.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) WD40 PF00400.32 KIK49746.1 - 2.9e-71 233.6 52.4 1.9e-10 41.1 0.1 9.3 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49746.1 - 2.3e-20 72.7 12.6 0.0093 16.2 0.0 7.9 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK49746.1 - 1.7e-10 40.8 5.6 0.0043 16.4 0.0 5.3 3 2 1 5 5 5 5 WD40-like domain PQQ_3 PF13570.6 KIK49746.1 - 0.00012 22.4 6.8 0.63 10.6 0.1 6.2 8 0 0 8 8 8 1 PQQ-like domain Frtz PF11768.8 KIK49746.1 - 0.00013 20.4 0.4 7.3 4.8 0.0 5.1 1 1 3 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK49746.1 - 0.00044 19.0 3.5 0.95 8.0 0.1 3.7 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK49746.1 - 0.00075 18.1 6.5 0.18 10.3 0.1 3.2 2 1 2 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.12 KIK49746.1 - 0.0024 17.8 0.3 1.1e+02 2.9 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.6 KIK49746.1 - 0.0044 17.3 11.2 1.6 9.2 0.2 4.9 5 0 0 5 5 5 2 Kelch motif Ge1_WD40 PF16529.5 KIK49746.1 - 0.017 14.1 9.7 3.6 6.4 0.1 5.9 1 1 5 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PDH PF02153.17 KIK49749.1 - 0.034 13.1 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase YceD PF02620.17 KIK49749.1 - 0.26 11.4 0.0 0.31 11.2 0.0 1.2 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD Sugar_tr PF00083.24 KIK49751.1 - 0.074 11.9 0.2 0.08 11.8 0.2 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Jacalin PF01419.17 KIK49752.1 - 3.7e-06 26.9 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Jacalin-like lectin domain WD40 PF00400.32 KIK49753.1 - 3.9e-114 369.3 33.8 3.4e-10 40.3 0.2 12.4 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49753.1 - 1.4e-51 172.8 4.0 0.0048 17.2 0.0 12.2 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK49753.1 - 9.1e-24 82.8 4.9 0.95 9.5 0.0 11.7 12 0 0 12 12 12 6 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK49753.1 - 2e-14 53.9 0.0 0.0032 17.4 0.0 4.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK49753.1 - 9.7e-14 51.1 7.7 1.5 7.7 0.0 9.9 1 1 10 11 11 11 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK49753.1 - 2.7e-09 35.9 0.0 2.7 6.2 0.0 7.7 4 3 4 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK49753.1 - 3.1e-09 36.6 0.0 3.1 7.0 0.0 7.9 7 2 0 7 7 7 1 WD40-like domain PQQ PF01011.21 KIK49753.1 - 4.5e-06 26.3 0.0 26 5.0 0.0 8.1 10 0 0 10 10 9 0 PQQ enzyme repeat DHFR_2 PF06442.11 KIK49753.1 - 9.8e-05 22.1 6.5 67 3.4 0.2 7.5 4 3 4 8 8 8 0 R67 dihydrofolate reductase PQQ_3 PF13570.6 KIK49753.1 - 0.00012 22.4 7.6 26 5.5 0.0 7.4 5 4 3 8 8 8 0 PQQ-like domain DUF4265 PF14085.6 KIK49753.1 - 0.0012 18.7 0.6 0.6 10.1 0.0 4.8 4 2 2 6 6 6 1 Domain of unknown function (DUF4265) Proteasome_A_N PF10584.9 KIK49753.1 - 0.0017 18.0 19.6 12 5.7 0.1 10.1 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KIK49753.1 - 0.0042 15.8 0.2 22 3.5 0.0 5.4 4 2 3 7 7 7 0 Nucleoporin Nup120/160 PAXIP1_C PF15364.6 KIK49753.1 - 0.044 14.1 0.5 0.073 13.4 0.5 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Cuticle_4 PF15955.5 KIK49753.1 - 7.7 7.3 9.1 42 4.9 0.0 5.4 7 0 0 7 7 7 0 Cuticle protein Menin PF05053.13 KIK49755.1 - 6 5.1 6.7 6.5 5.0 6.7 1.0 1 0 0 1 1 1 0 Menin Arm_3 PF16186.5 KIK49757.1 - 2e-18 65.7 0.1 2.9e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Atypical Arm repeat nec1 PF10379.9 KIK49757.1 - 0.016 14.7 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Virulence protein nec1 EIID-AGA PF03613.14 KIK49764.1 - 0.084 12.0 0.0 0.084 12.0 0.0 1.0 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component NACHT PF05729.12 KIK49765.1 - 7.3e-07 29.2 0.0 8.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK49765.1 - 5.4e-06 26.9 0.0 9.7e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK49765.1 - 5.8e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK49765.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK49765.1 - 0.0043 16.8 0.1 0.021 14.5 0.1 2.0 1 1 1 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.9 KIK49765.1 - 0.0046 16.2 0.0 0.0048 16.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK49765.1 - 0.019 15.3 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK49765.1 - 0.021 14.5 0.0 0.024 14.4 0.0 1.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK49765.1 - 0.025 14.1 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KIK49765.1 - 0.026 14.9 0.1 0.043 14.2 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK49765.1 - 0.033 14.7 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK49765.1 - 0.05 12.8 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KIK49765.1 - 0.061 12.7 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KIK49765.1 - 0.067 13.1 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KIK49765.1 - 0.071 12.8 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_PrkA PF08298.11 KIK49765.1 - 0.15 11.0 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Glyco_hydro_129 PF11308.8 KIK49765.1 - 0.15 11.2 0.0 0.17 11.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 TIP49 PF06068.13 KIK49765.1 - 0.16 11.1 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KIK49765.1 - 0.18 12.0 0.2 0.44 10.7 0.1 1.5 1 1 1 2 2 2 0 AAA domain PIF1 PF05970.14 KIK49765.1 - 0.19 10.9 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 KIK49765.1 - 0.2 11.5 0.1 0.33 10.8 0.1 1.7 1 1 0 1 1 1 0 NTPase DEAD PF00270.29 KIK49766.1 - 4.8e-12 46.0 0.0 6.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK49766.1 - 9.3e-09 35.5 0.0 1.8e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK49766.1 - 0.054 13.8 0.1 0.15 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK49767.1 - 1.3e-133 430.9 92.4 2.4e-10 40.8 1.7 15.5 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49767.1 - 3.9e-47 158.5 3.2 0.024 15.0 0.0 15.0 1 1 12 15 15 15 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK49767.1 - 5.7e-30 104.4 12.1 0.018 14.0 0.0 14.1 3 1 11 14 14 14 12 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK49767.1 - 8.8e-19 67.0 27.2 3.5 7.7 0.0 14.0 14 0 0 14 14 14 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK49767.1 - 5.6e-12 45.6 0.0 4.2 6.6 0.0 9.3 8 3 3 11 11 11 2 WD40-like domain NACHT PF05729.12 KIK49767.1 - 1.7e-09 37.8 0.0 4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PQQ PF01011.21 KIK49767.1 - 0.0026 17.6 3.9 11 6.2 0.0 7.1 9 0 0 9 9 9 0 PQQ enzyme repeat AAA_16 PF13191.6 KIK49767.1 - 0.0061 16.9 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 KIK49767.1 - 0.0084 14.8 21.8 11 4.5 0.1 10.5 10 4 3 13 13 13 0 Nucleoporin Nup120/160 AAA PF00004.29 KIK49767.1 - 0.027 14.9 0.7 0.81 10.1 0.2 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KIK49767.1 - 0.04 13.0 0.1 0.08 12.0 0.1 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DPPIV_N PF00930.21 KIK49767.1 - 0.041 12.7 1.8 17 4.0 0.0 5.4 4 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.6 KIK49767.1 - 0.05 12.9 13.6 26 4.0 0.0 8.8 5 2 4 10 10 10 0 Neuroblastoma-amplified sequence, N terminal RNA_helicase PF00910.22 KIK49767.1 - 0.088 13.2 0.2 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 RNA helicase UPF0122 PF04297.14 KIK49767.1 - 0.1 12.8 0.2 0.33 11.2 0.2 1.8 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like APS_kinase PF01583.20 KIK49767.1 - 0.21 11.5 0.2 0.48 10.3 0.2 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Cuticle_4 PF15955.5 KIK49767.1 - 1.2 9.8 12.0 2.3e+02 2.5 0.0 7.8 11 0 0 11 11 9 0 Cuticle protein PQQ_2 PF13360.6 KIK49767.1 - 3.9 7.0 20.9 3.2e+02 0.7 9.7 5.1 1 1 1 2 2 2 0 PQQ-like domain Rep_fac-A_3 PF08661.11 KIK49768.1 - 0.0001 22.6 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Replication factor A protein 3 RVT_2 PF07727.14 KIK49770.1 - 0.021 14.5 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C53 PF05550.11 KIK49772.1 - 0.053 13.2 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 zf-RING_UBOX PF13445.6 KIK49773.1 - 2.1e-09 37.3 3.6 2.1e-09 37.3 3.6 2.1 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK49773.1 - 5.9e-09 35.9 9.7 1.2e-08 34.9 9.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIK49773.1 - 1.1e-08 34.8 6.4 2.7e-08 33.6 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK49773.1 - 1.2e-08 34.7 4.5 2.1e-08 33.9 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK49773.1 - 5.4e-08 32.7 5.7 1.2e-07 31.6 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK49773.1 - 8.9e-08 32.3 6.6 8.9e-08 32.3 6.6 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK49773.1 - 2e-07 30.8 9.5 6.6e-07 29.1 9.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK49773.1 - 6.6e-05 22.7 7.0 0.0011 18.8 7.4 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIK49773.1 - 0.06 13.2 7.4 0.091 12.6 3.0 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIK49773.1 - 0.13 12.6 6.8 0.64 10.4 6.0 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KIK49773.1 - 0.24 11.3 5.4 0.21 11.4 3.7 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KIK49773.1 - 1.1 9.2 5.7 5.4 7.0 5.8 2.1 1 1 0 1 1 1 0 PHD-finger zf-RING_10 PF16685.5 KIK49773.1 - 1.1 9.4 9.0 1.3 9.2 6.1 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 FYVE PF01363.21 KIK49773.1 - 1.2 9.3 5.8 0.78 9.9 3.2 2.0 2 1 0 2 2 2 0 FYVE zinc finger zf-MIZ PF02891.20 KIK49773.1 - 1.8 8.4 7.6 5.8 6.8 7.6 1.9 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.6 KIK49773.1 - 2.8 7.9 8.7 39 4.2 8.6 2.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Elf1 PF05129.13 KIK49773.1 - 6.2 6.9 6.5 2.6 8.1 0.7 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-CCHC PF00098.23 KIK49775.1 - 3.2e-05 23.8 3.8 4.9e-05 23.2 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Amidoligase_2 PF12224.8 KIK49776.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme Plavaka PF18759.1 KIK49783.1 - 5.5e-32 111.3 0.0 6.1e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK49784.1 - 4.7e-14 52.4 0.0 6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase AcetylCoA_hyd_C PF13336.6 KIK49787.1 - 2.3e-36 125.1 0.0 2.6e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK49788.1 - 1.1e-127 412.1 85.1 1.9e-10 41.1 2.8 13.8 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49788.1 - 2.8e-34 117.3 22.8 0.0032 17.7 0.0 12.9 1 1 12 13 13 13 11 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK49788.1 - 1.5e-17 63.9 10.8 0.0027 17.1 0.2 7.9 3 2 6 10 10 10 4 WD40-like domain Cytochrom_D1 PF02239.16 KIK49788.1 - 4.5e-09 35.3 17.6 0.0018 16.9 0.4 5.4 2 1 3 6 6 6 4 Cytochrome D1 heme domain Frtz PF11768.8 KIK49788.1 - 1.6e-08 33.4 1.5 8.9 4.5 0.0 8.4 2 1 7 10 10 10 1 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK49788.1 - 4.8e-07 29.8 0.0 1.9e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KIK49788.1 - 8.1e-07 29.1 6.1 0.11 12.3 0.0 5.0 1 1 5 6 6 6 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK49788.1 - 6.2e-06 25.4 13.6 0.36 9.7 0.1 8.4 1 1 7 9 9 9 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CHAP PF05257.16 KIK49788.1 - 9.3e-06 26.1 25.1 0.28 11.8 0.1 8.5 1 1 7 8 8 8 1 CHAP domain Me-amine-dh_H PF06433.11 KIK49788.1 - 9.6e-05 21.4 0.3 0.35 9.7 0.0 4.6 5 1 1 6 6 6 1 Methylamine dehydrogenase heavy chain (MADH) PQQ_3 PF13570.6 KIK49788.1 - 0.00012 22.5 21.0 1.9 9.1 0.2 9.3 11 1 0 11 11 10 2 PQQ-like domain AAA_16 PF13191.6 KIK49788.1 - 0.0002 21.8 0.0 0.00049 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK49788.1 - 0.00046 19.4 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK49788.1 - 0.032 14.6 0.1 0.54 10.7 0.0 3.1 3 0 0 3 3 3 0 RNA helicase Kelch_6 PF13964.6 KIK49788.1 - 0.058 13.7 16.7 2.4 8.6 0.1 6.2 7 0 0 7 7 6 0 Kelch motif Robl_LC7 PF03259.17 KIK49788.1 - 0.08 12.7 0.9 4.1 7.3 0.0 3.8 4 0 0 4 4 4 0 Roadblock/LC7 domain POLO_box PF00659.18 KIK49788.1 - 0.096 12.9 2.7 27 5.1 0.0 5.1 5 1 0 5 5 4 0 POLO box duplicated region PD40 PF07676.12 KIK49788.1 - 0.28 11.2 11.6 84 3.3 0.0 8.1 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK49788.1 - 0.45 10.5 7.1 9 6.4 0.0 6.3 9 0 0 9 9 9 0 PQQ enzyme repeat Sulfotransfer_3 PF13469.6 KIK49791.1 - 0.045 14.1 0.0 0.06 13.7 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase family DUF3884 PF13024.6 KIK49792.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Phytoreo_S7 PF07236.11 KIK49794.1 - 0.027 12.8 0.0 0.027 12.8 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein CRAL_TRIO PF00650.20 KIK49796.1 - 2.6e-24 85.7 0.0 3.5e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain WD40 PF00400.32 KIK49798.1 - 2.9e-152 490.0 49.1 1.9e-10 41.2 0.2 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49798.1 - 2.6e-41 139.8 12.0 0.0048 17.2 0.1 14.0 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK49798.1 - 7e-24 84.8 2.8 0.0013 18.6 0.0 6.7 1 1 7 9 9 9 9 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK49798.1 - 1.7e-16 60.5 9.8 0.61 9.4 0.0 12.5 11 2 3 14 14 14 5 WD40-like domain Nup160 PF11715.8 KIK49798.1 - 1.2e-15 57.2 16.4 0.21 10.2 0.0 11.3 6 3 3 13 13 13 6 Nucleoporin Nup120/160 PD40 PF07676.12 KIK49798.1 - 3.1e-10 39.7 0.9 67 3.6 0.0 11.1 14 0 0 14 14 14 0 WD40-like Beta Propeller Repeat COPI_C PF06957.11 KIK49798.1 - 3.9e-07 29.2 0.0 4.7 5.9 0.0 7.1 3 2 1 7 7 7 2 Coatomer (COPI) alpha subunit C-terminus NHL PF01436.21 KIK49798.1 - 4.8e-07 29.5 21.5 16 5.8 0.1 11.5 12 0 0 12 12 12 0 NHL repeat nos_propeller PF18764.1 KIK49798.1 - 8.5e-06 25.6 28.2 22 5.0 0.0 12.5 14 0 0 14 14 14 0 Nitrous oxide reductase propeller repeat AsnC_trans_reg PF01037.21 KIK49798.1 - 0.00019 21.3 6.4 59 3.7 0.0 8.6 12 0 0 12 12 12 0 Lrp/AsnC ligand binding domain SdiA-regulated PF06977.11 KIK49798.1 - 0.0006 19.1 0.0 28 3.8 0.0 5.0 2 2 3 6 6 6 0 SdiA-regulated Nucleoporin_N PF08801.11 KIK49798.1 - 0.00073 18.4 14.8 0.0033 16.2 4.8 6.0 1 1 6 7 7 7 1 Nup133 N terminal like LRR_10 PF18805.1 KIK49798.1 - 0.011 15.4 17.6 64 3.3 0.0 9.8 10 2 2 12 12 12 0 Leucine-rich repeat Me-amine-dh_H PF06433.11 KIK49798.1 - 0.021 13.7 0.1 42 2.9 0.0 4.3 3 2 1 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) DUF2574 PF10836.8 KIK49798.1 - 0.27 11.2 5.3 48 3.9 0.0 6.4 5 3 4 9 9 9 0 Protein of unknown function (DUF2574) DsbC_N PF10411.9 KIK49798.1 - 0.86 9.1 16.1 2.2e+02 1.4 0.0 9.5 14 0 0 14 14 13 0 Disulfide bond isomerase protein N-terminus PASTA PF03793.19 KIK49799.1 - 0.0061 16.4 0.1 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 PASTA domain zf-CCHC PF00098.23 KIK49800.1 - 1.2e-05 25.1 4.0 1.8e-05 24.6 4.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIK49800.1 - 0.0035 17.0 2.5 0.0055 16.4 2.5 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KIK49800.1 - 0.0093 15.8 2.1 0.013 15.3 2.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Docking PF08990.11 KIK49801.1 - 0.12 12.0 0.5 0.28 10.8 0.5 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking VasI PF11319.8 KIK49803.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 DEAD PF00270.29 KIK49805.1 - 1.6e-08 34.5 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OrsD PF12013.8 KIK49805.1 - 1.1e-07 32.2 0.0 2.9e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 KIK49805.1 - 1.1e-06 28.9 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK49805.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3860 PF12976.7 KIK49805.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) AbiJ_NTD4 PF18863.1 KIK49805.1 - 0.15 12.6 0.3 7.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AbiJ N-terminal domain 4 Cnl2_NKP2 PF09447.10 KIK49807.1 - 0.038 14.2 0.3 0.068 13.3 0.3 1.4 1 0 0 1 1 1 0 Cnl2/NKP2 family protein TPR_15 PF13429.6 KIK49808.1 - 0.006 15.8 0.7 0.006 15.8 0.7 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat CENP-Q PF13094.6 KIK49808.1 - 0.067 13.4 0.4 0.067 13.4 0.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PH_9 PF15410.6 KIK49809.1 - 3.3e-25 88.8 0.0 4.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK49809.1 - 0.00043 20.8 0.0 0.00091 19.7 0.0 1.6 1 1 0 1 1 1 1 PH domain TRI5 PF06330.11 KIK49810.1 - 6.5e-14 51.6 0.1 8e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) CRAL_TRIO PF00650.20 KIK49814.1 - 2.1e-36 125.0 0.1 5.2e-36 123.8 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain DUF2457 PF10446.9 KIK49815.1 - 0.00079 18.7 0.0 0.00098 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) HCV_NS5a_1b PF08301.13 KIK49824.1 - 0.15 12.6 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b DPCD PF14913.6 KIK49824.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 DPCD protein family Ribonuclease_T2 PF00445.18 KIK49825.1 - 0.094 12.9 0.1 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease T2 family Csm2_III-A PF03750.13 KIK49825.1 - 0.78 10.6 3.0 1.9 9.4 1.5 2.1 1 1 1 2 2 2 0 Csm2 Type III-A DDE_1 PF03184.19 KIK49826.1 - 1.2e-08 34.8 0.0 1.8e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIK49827.1 - 0.00017 21.3 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PLDc_2 PF13091.6 KIK49827.1 - 0.049 13.5 0.0 0.061 13.2 0.0 1.3 1 1 0 1 1 1 0 PLD-like domain MscS_porin PF12795.7 KIK49828.1 - 0.00056 19.5 0.5 0.00072 19.2 0.5 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain bZIP_1 PF00170.21 KIK49828.1 - 0.00067 19.7 0.5 0.0052 16.9 0.2 2.1 1 1 1 2 2 2 1 bZIP transcription factor Shugoshin_N PF07558.11 KIK49828.1 - 0.25 11.2 3.5 0.38 10.7 0.8 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Plavaka PF18759.1 KIK49829.1 - 4.6e-36 124.7 0.0 1.1e-35 123.5 0.1 1.6 2 0 0 2 2 2 1 Plavaka transposase Peptidase_M16 PF00675.20 KIK49829.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) CxC4 PF18717.1 KIK49834.1 - 8e-37 126.0 0.2 1.6e-36 125.0 0.0 1.6 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK49835.1 - 3e-07 30.3 0.9 3.5e-07 30.1 0.9 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Glyco_transf_25 PF01755.17 KIK49835.1 - 0.041 13.7 0.6 0.063 13.1 0.6 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) MBOAT_2 PF13813.6 KIK49838.1 - 6.2e-13 48.8 3.7 1e-12 48.1 3.7 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2079 PF09852.9 KIK49838.1 - 0.02 13.8 0.3 0.025 13.5 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF4131 PF13567.6 KIK49839.1 - 1.4 8.5 5.8 0.31 10.7 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Asp PF00026.23 KIK49847.1 - 3.3e-26 92.4 10.5 3e-17 63.0 1.3 3.1 2 1 1 3 3 3 3 Eukaryotic aspartyl protease RepB-RCR_reg PF10723.9 KIK49847.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB Phytoreo_S7 PF07236.11 KIK49849.1 - 0.12 10.7 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein DUF648 PF04890.13 KIK49854.1 - 0.073 12.8 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) HR1 PF02185.16 KIK49854.1 - 4 7.6 7.0 1.6 8.9 2.8 2.3 2 1 0 2 2 2 0 Hr1 repeat zf-CCHC PF00098.23 KIK49855.1 - 1e-05 25.4 3.8 1.7e-05 24.7 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KIK49855.1 - 0.00068 19.9 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein SF3A3 PF16837.5 KIK49857.1 - 0.0081 16.7 0.1 0.026 15.1 0.0 1.8 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 She9_MDM33 PF05546.11 KIK49857.1 - 0.057 13.2 0.8 0.16 11.8 0.1 1.8 1 1 1 2 2 2 0 She9 / Mdm33 family UxuA PF03786.13 KIK49857.1 - 0.1 11.4 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) AAA-ATPase_like PF09820.9 KIK49857.1 - 0.14 11.5 0.2 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Peptidase_C48 PF02902.19 KIK49858.1 - 7.9e-18 65.1 0.0 1.1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Msg2_C PF12373.8 KIK49859.1 - 0.016 14.6 0.4 7.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal AAA_16 PF13191.6 KIK49861.1 - 7.1e-09 36.3 0.0 9.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK49861.1 - 3.7e-08 33.5 0.0 1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK49861.1 - 5.5e-07 30.1 0.0 1e-06 29.2 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK49861.1 - 0.00013 22.3 0.0 0.00018 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KIK49861.1 - 0.0021 17.4 0.0 0.02 14.1 0.0 1.9 1 1 0 2 2 2 1 KAP family P-loop domain Parvo_NS1 PF01057.17 KIK49861.1 - 0.0029 16.8 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PIF1 PF05970.14 KIK49861.1 - 0.0066 15.7 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_7 PF12775.7 KIK49861.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIK49861.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK49861.1 - 0.018 14.3 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 KIK49861.1 - 0.023 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 KIK49861.1 - 0.035 14.2 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Torsin IstB_IS21 PF01695.17 KIK49861.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KIK49861.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KIK49861.1 - 0.15 11.9 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 KIK49861.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 KIK49861.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK49861.1 - 0.28 10.7 0.2 4.5 6.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK49862.1 - 6.5e-61 200.9 26.5 2.3e-10 40.9 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49862.1 - 8.4e-28 96.5 0.1 0.0011 19.3 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK49862.1 - 1.7e-16 59.7 4.1 0.094 12.7 0.1 6.7 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK49862.1 - 2.5e-07 30.0 0.1 4.4 6.2 0.0 5.6 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK49862.1 - 4.1e-07 30.1 0.0 0.00058 19.8 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KIK49862.1 - 8.2e-06 25.5 0.0 56 3.9 0.0 5.4 5 0 0 5 5 5 0 PQQ enzyme repeat Proteasome_A_N PF10584.9 KIK49862.1 - 1.4e-05 24.6 8.3 4.2 7.2 0.0 6.0 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature Glyco_hydro_30C PF17189.4 KIK49862.1 - 0.00017 21.8 1.1 1.7 8.9 0.1 5.4 1 1 2 3 3 3 1 Glycosyl hydrolase family 30 beta sandwich domain Cytochrom_D1 PF02239.16 KIK49862.1 - 0.0019 16.8 0.0 0.47 8.9 0.0 2.4 1 1 0 2 2 2 2 Cytochrome D1 heme domain Peptidase_S9_N PF02897.15 KIK49862.1 - 0.0022 16.9 0.0 4.1 6.1 0.0 3.9 1 1 3 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_3 PF13570.6 KIK49862.1 - 0.0031 18.0 0.0 88 3.8 0.0 4.5 4 1 1 5 5 5 0 PQQ-like domain Nucleoporin_N PF08801.11 KIK49862.1 - 0.0078 15.0 0.0 7.9 5.1 0.0 3.5 1 1 3 4 4 4 1 Nup133 N terminal like FCP1_C PF09309.10 KIK49862.1 - 0.013 15.4 0.0 7.3 6.4 0.0 3.9 1 1 4 5 5 5 0 FCP1, C-terminal Pyr_redox_dim PF02852.22 KIK49862.1 - 0.031 14.5 0.0 26 5.1 0.0 3.9 2 2 3 5 5 5 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF5122 PF17164.4 KIK49862.1 - 0.079 13.3 1.1 9.6 6.6 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Frtz PF11768.8 KIK49862.1 - 0.27 9.5 0.0 14 3.9 0.0 2.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK49862.1 - 2.7 7.2 6.6 26 4.0 0.1 3.8 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Ank_2 PF12796.7 KIK49863.1 - 2e-27 95.6 22.0 5.5e-11 42.9 0.3 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK49863.1 - 4.4e-23 81.3 5.8 0.00037 21.0 0.0 7.5 3 3 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK49863.1 - 8.7e-21 71.8 14.9 0.08 13.5 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KIK49863.1 - 2.1e-17 62.7 33.0 0.0052 17.2 0.9 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KIK49863.1 - 1.3e-10 41.3 14.4 0.018 15.4 0.1 6.3 2 2 5 7 7 7 5 Ankyrin repeats (many copies) YmgB PF10798.8 KIK49863.1 - 0.043 13.6 0.3 5.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Spc7 PF08317.11 KIK49864.1 - 0.0087 15.0 12.0 0.013 14.4 12.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 KIK49864.1 - 0.017 13.8 2.4 0.022 13.4 2.4 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.10 KIK49864.1 - 0.021 14.9 0.4 0.045 13.8 0.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Taxilin PF09728.9 KIK49864.1 - 0.026 13.7 10.6 0.036 13.2 10.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein GAS PF13851.6 KIK49864.1 - 0.081 12.3 10.8 0.24 10.7 3.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 KIK49864.1 - 0.098 12.7 16.2 0.15 12.1 8.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 KIK49864.1 - 0.23 11.3 8.5 1.6 8.5 3.8 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1664 PF07889.12 KIK49864.1 - 0.34 10.9 2.3 0.7 9.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 KIK49864.1 - 0.38 10.6 13.5 0.69 9.7 13.2 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH LRS4 PF10422.9 KIK49864.1 - 0.45 10.0 7.6 0.7 9.4 7.6 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fez1 PF06818.15 KIK49864.1 - 0.56 10.6 13.1 0.97 9.8 9.5 1.9 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 KIK49864.1 - 0.58 10.8 10.6 2 9.1 2.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Spc42p PF11544.8 KIK49864.1 - 0.61 10.1 4.1 13 5.8 1.5 3.2 1 1 0 2 2 2 0 Spindle pole body component Spc42p Csm1_N PF18504.1 KIK49864.1 - 0.8 10.1 15.5 0.57 10.6 4.7 3.3 1 1 3 4 4 4 0 Csm1 N-terminal domain DUF641 PF04859.12 KIK49864.1 - 1.2 9.4 7.2 0.71 10.2 3.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BRE1 PF08647.11 KIK49864.1 - 1.5 9.0 13.5 5.5 7.1 1.2 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase PKcGMP_CC PF16808.5 KIK49864.1 - 2.1 8.2 10.9 2.1 8.3 1.5 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMCO5 PF14992.6 KIK49864.1 - 2.2 7.8 11.0 0.66 9.5 7.7 1.8 2 0 0 2 2 2 0 TMCO5 family Lebercilin PF15619.6 KIK49864.1 - 2.5 7.7 17.0 7.1 6.2 16.5 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.19 KIK49864.1 - 2.5 5.9 4.9 3.2 5.6 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 KIK49864.1 - 2.9 8.1 14.4 2 8.6 1.3 3.4 2 1 1 3 3 3 0 bZIP transcription factor Sec2p PF06428.11 KIK49864.1 - 3.1 7.8 12.1 0.72 9.9 1.2 2.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF465 PF04325.13 KIK49864.1 - 3.3 7.8 6.6 5.7 7.1 2.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF465) DUF724 PF05266.14 KIK49864.1 - 3.3 7.5 11.5 2.3 8.0 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 KIK49864.1 - 5.4 7.1 13.9 2.5e+02 1.7 14.8 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DEC-1_N PF04625.13 KIK49864.1 - 6.3 5.7 7.7 0.12 11.4 0.2 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF4407 PF14362.6 KIK49864.1 - 6.8 6.0 8.2 10 5.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 KIK49865.1 - 0.00039 20.6 0.0 0.00078 19.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK49865.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) ADH_zinc_N PF00107.26 KIK49868.1 - 1.2e-09 38.3 0.0 2.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK49868.1 - 2.2e-08 34.0 0.0 4.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIK49868.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CNH PF00780.22 KIK49869.1 - 6.3e-47 160.5 0.0 1e-46 159.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIK49869.1 - 3.6e-25 88.6 0.3 8.5e-25 87.4 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KIK49869.1 - 1.1e-06 28.6 0.4 3.6e-06 26.9 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Sof1 PF04158.14 KIK49873.1 - 0.047 14.0 3.9 0.065 13.5 3.9 1.2 1 0 0 1 1 1 0 Sof1-like domain PRP9_N PF16958.5 KIK49873.1 - 0.079 13.0 2.0 0.06 13.4 1.0 1.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus LST1 PF05083.13 KIK49873.1 - 0.1 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 LST-1 protein DUF2500 PF10694.9 KIK49873.1 - 0.11 13.0 0.5 0.23 12.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) HupE_UreJ_2 PF13795.6 KIK49878.1 - 0.043 13.5 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 HupE / UreJ protein SRP54_N PF02881.19 KIK49879.1 - 0.34 11.2 0.9 13 6.1 0.9 2.3 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain Dimer_Tnp_hAT PF05699.14 KIK49880.1 - 4.9e-10 39.1 0.1 5.2e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1685 PF07939.11 KIK49881.1 - 0.0085 15.8 0.1 0.012 15.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1685) CT_C_D PF02682.16 KIK49881.1 - 0.15 11.7 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D RT_RNaseH PF17917.1 KIK49882.1 - 0.0004 20.6 0.0 0.00062 20.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_trans_4_5 PF16994.5 KIK49882.1 - 0.059 13.0 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase family 4 WD40 PF00400.32 KIK49884.1 - 0.00017 22.3 1.1 0.00023 21.9 0.2 1.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ATG11 PF10377.9 KIK49887.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 Retrotrans_gag PF03732.17 KIK49888.1 - 5.2e-06 26.6 0.0 1.5e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK49888.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) TPR_1 PF00515.28 KIK49889.1 - 0.066 13.1 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK49889.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TSNAXIP1_N PF15739.5 KIK49890.1 - 0.0032 17.8 2.2 0.0053 17.1 2.2 1.3 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus CdvA PF18822.1 KIK49890.1 - 0.0036 17.1 1.6 0.0064 16.3 1.6 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain SYCE1 PF15233.6 KIK49890.1 - 0.0065 16.6 3.3 0.0097 16.0 3.3 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Gp-FAR-1 PF05823.12 KIK49890.1 - 0.023 15.0 1.4 0.037 14.4 1.4 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4164 PF13747.6 KIK49890.1 - 0.031 14.5 1.7 0.048 13.9 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Tex_N PF09371.10 KIK49890.1 - 0.039 13.6 1.7 0.06 13.0 1.7 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain APG6_N PF17675.1 KIK49890.1 - 0.046 14.3 5.3 0.07 13.7 5.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region JIP_LZII PF16471.5 KIK49890.1 - 0.59 10.3 5.5 7 6.9 0.1 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 KIK49890.1 - 1 9.6 9.5 0.27 11.5 1.2 2.8 1 1 1 2 2 2 0 Homeobox associated leucine zipper LMP PF04778.12 KIK49891.1 - 0.0041 17.0 4.9 0.0041 17.0 4.9 3.1 2 1 1 3 3 3 1 LMP repeated region Spc7 PF08317.11 KIK49891.1 - 0.062 12.2 20.9 0.007 15.3 15.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein CDPS PF16715.5 KIK49891.1 - 0.12 12.0 3.7 0.14 11.8 3.7 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF3810 PF12725.7 KIK49891.1 - 0.17 11.2 1.9 0.19 11.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) APG6_N PF17675.1 KIK49891.1 - 0.21 12.1 23.8 0.37 11.3 2.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region HisKA_3 PF07730.13 KIK49891.1 - 0.26 11.8 5.7 0.66 10.5 1.2 2.9 1 1 1 2 2 2 0 Histidine kinase Fez1 PF06818.15 KIK49891.1 - 0.82 10.1 18.4 1.3 9.4 18.4 1.4 1 1 0 1 1 1 0 Fez1 CortBP2 PF09727.9 KIK49891.1 - 1.1 9.2 18.9 0.11 12.4 13.2 1.9 1 1 1 2 2 2 0 Cortactin-binding protein-2 TPR_MLP1_2 PF07926.12 KIK49891.1 - 1.3 9.0 22.6 2.5 8.2 14.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 KIK49891.1 - 3 8.0 23.0 1.4 9.0 16.9 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Tup_N PF08581.10 KIK49891.1 - 3.4 8.0 14.9 0.39 11.1 6.6 2.8 2 1 1 3 3 3 0 Tup N-terminal Exonuc_VII_L PF02601.15 KIK49891.1 - 4.1 6.9 12.5 5 6.6 12.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 KIK49891.1 - 4.2 8.0 21.3 0.16 12.6 6.8 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KIK49891.1 - 4.5 8.0 16.4 1.1 10.0 2.3 2.8 1 1 1 3 3 3 0 Initiation control protein YabA KxDL PF10241.9 KIK49891.1 - 5.5 7.3 14.6 1 9.7 7.1 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 KIK49891.1 - 6.3 6.1 14.9 13 5.0 14.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 KIK49891.1 - 7.5 6.8 15.4 9.8 6.5 15.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_C48 PF02902.19 KIK49892.1 - 1e-16 61.4 0.1 1.7e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3717 PF12512.8 KIK49892.1 - 0.063 13.2 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) Peptidase_C39 PF03412.15 KIK49892.1 - 0.074 12.9 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase C39 family PACT_coil_coil PF10495.9 KIK49893.1 - 2.3e-05 24.9 0.0 0.41 11.3 0.0 2.4 2 0 0 2 2 2 2 Pericentrin-AKAP-450 domain of centrosomal targeting protein Adaptin_N PF01602.20 KIK49893.1 - 0.021 13.4 0.0 0.48 8.9 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Med2 PF11214.8 KIK49893.1 - 0.024 14.8 0.5 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 2 PIG-L PF02585.17 KIK49893.1 - 0.054 14.1 0.5 7.6 7.2 0.0 2.5 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase Inhibitor_I66 PF16850.5 KIK49898.1 - 1.2e-28 99.8 0.0 1.4e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 CxC4 PF18717.1 KIK49902.1 - 5.4e-43 146.0 0.0 1.2e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK49902.1 - 2.9e-05 23.8 0.5 5.1e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Glyco_transf_25 PF01755.17 KIK49902.1 - 0.24 11.2 0.3 0.44 10.4 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Peptidase_C48 PF02902.19 KIK49904.1 - 2.7e-14 53.5 0.2 3.6e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3717 PF12512.8 KIK49904.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) CENP-F_leu_zip PF10473.9 KIK49906.1 - 0.029 14.4 29.9 0.014 15.4 26.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIK49906.1 - 0.065 12.1 28.4 0.099 11.5 17.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KIK49906.1 - 0.078 13.0 33.4 0.017 15.2 21.4 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 KIK49906.1 - 0.12 10.7 25.9 0.14 10.5 25.9 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1599 PF07659.11 KIK49906.1 - 0.17 12.4 0.6 5.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 SMODS PF18144.1 KIK49906.1 - 0.23 11.6 2.4 0.59 10.3 0.2 2.4 1 1 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Tup_N PF08581.10 KIK49906.1 - 0.42 10.9 16.4 0.13 12.6 4.1 3.2 2 1 1 3 3 3 0 Tup N-terminal DUF948 PF06103.11 KIK49906.1 - 0.48 10.7 6.1 0.73 10.1 1.1 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KIK49906.1 - 0.54 10.8 31.8 0.26 11.8 13.5 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region SesA PF17107.5 KIK49906.1 - 1.3 9.2 12.3 0.79 9.9 3.7 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ATG16 PF08614.11 KIK49906.1 - 1.5 9.0 28.2 21 5.3 26.2 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KIK49906.1 - 1.7 9.1 25.9 0.69 10.3 10.0 2.1 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 KIK49906.1 - 1.9 7.7 19.8 0.69 9.2 8.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) FUSC PF04632.12 KIK49906.1 - 2.9 6.3 5.4 1.9 6.9 3.6 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family YtxH PF12732.7 KIK49906.1 - 2.9 8.5 7.9 4.4e+02 1.5 7.9 2.8 1 1 0 1 1 1 0 YtxH-like protein FapA PF03961.13 KIK49906.1 - 5.4 5.5 21.0 1.6 7.3 12.8 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KIK49906.1 - 6 6.9 26.2 0.37 10.9 11.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KIK49906.1 - 6.9 6.0 29.9 12 5.2 20.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.8 KIK49906.1 - 8 6.0 18.2 0.5 10.0 8.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CdvA PF18822.1 KIK49907.1 - 0.0037 17.1 1.7 0.0063 16.3 1.7 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain TSNAXIP1_N PF15739.5 KIK49907.1 - 0.0062 16.9 1.9 0.0098 16.3 1.9 1.3 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus Tex_N PF09371.10 KIK49907.1 - 0.008 15.9 2.0 0.013 15.2 2.0 1.3 1 0 0 1 1 1 1 Tex-like protein N-terminal domain SYCE1 PF15233.6 KIK49907.1 - 0.0091 16.1 2.4 0.014 15.5 2.4 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Gp-FAR-1 PF05823.12 KIK49907.1 - 0.017 15.5 1.6 0.026 14.9 1.6 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) APG6_N PF17675.1 KIK49907.1 - 0.019 15.5 2.8 0.03 14.9 2.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4164 PF13747.6 KIK49907.1 - 0.076 13.3 2.2 0.13 12.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HALZ PF02183.18 KIK49907.1 - 0.58 10.4 8.4 0.32 11.3 1.5 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper CASP_C PF08172.12 KIK49907.1 - 1.5 8.1 6.6 0.33 10.3 3.5 1.4 2 0 0 2 2 2 0 CASP C terminal TPR_1 PF00515.28 KIK49908.1 - 0.055 13.3 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK49908.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK49908.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat AcetylCoA_hydro PF02550.15 KIK49910.1 - 7.3e-22 78.3 0.0 9.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain NACHT PF05729.12 KIK49912.1 - 2e-09 37.6 0.0 3.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.14 KIK49912.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.6 KIK49912.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 KIK49912.1 - 0.021 14.1 0.1 0.038 13.2 0.1 1.3 1 1 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.9 KIK49912.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK49912.1 - 0.025 14.6 0.0 0.097 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK49912.1 - 0.033 13.4 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KIK49912.1 - 0.034 14.5 0.1 0.087 13.2 0.1 1.8 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIK49912.1 - 0.047 14.0 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK49912.1 - 0.063 13.2 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KIK49912.1 - 0.13 12.8 0.6 0.34 11.4 0.3 1.7 2 1 0 2 2 2 0 ABC transporter Ank_2 PF12796.7 KIK49913.1 - 5.2e-25 87.8 9.6 1.1e-10 41.9 0.6 3.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK49913.1 - 6.1e-24 84.1 3.0 4e-06 27.3 0.4 7.4 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK49913.1 - 2e-19 67.6 14.0 0.012 16.1 0.1 7.6 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KIK49913.1 - 1.9e-16 59.7 24.9 0.007 16.8 0.1 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KIK49913.1 - 2.9e-11 43.4 12.4 0.002 18.4 0.4 6.1 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Cauli_VI PF01693.16 KIK49915.1 - 4.3e-07 30.1 0.4 8.2e-07 29.2 0.4 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF4232 PF14016.6 KIK49916.1 - 0.016 15.4 0.2 0.018 15.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) B1 PF02246.15 KIK49916.1 - 0.057 13.5 0.9 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein L b1 domain TSGA13 PF14994.6 KIK49918.1 - 0.22 10.9 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 Testis-specific gene 13 protein DUF746 PF05344.11 KIK49919.1 - 0.0028 17.4 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) HU-CCDC81_euk_2 PF18289.1 KIK49919.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 SWIB PF02201.18 KIK49920.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain Retrotrans_gag PF03732.17 KIK49921.1 - 7.8e-07 29.3 0.2 1.9e-06 28.0 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK49921.1 - 0.011 15.5 0.1 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) Csm1_N PF18504.1 KIK49922.1 - 0.08 13.3 0.9 0.17 12.2 0.9 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain CAMSAP_CC1 PF17095.5 KIK49923.1 - 0.06 13.2 1.0 0.14 12.0 1.0 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin UPF0242 PF06785.11 KIK49923.1 - 0.068 13.3 8.1 0.023 14.8 5.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 KIK49923.1 - 0.074 12.5 7.9 0.11 11.9 7.9 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK49923.1 - 0.082 11.8 10.0 0.12 11.3 10.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KIK49923.1 - 0.33 11.0 8.9 0.87 9.7 8.9 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 KIK49923.1 - 0.36 11.0 9.3 5.5 7.2 2.5 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 KIK49923.1 - 0.47 10.5 2.1 1 9.4 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4337 PF14235.6 KIK49923.1 - 1.1 9.4 3.4 1.8 8.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fib_alpha PF08702.10 KIK49923.1 - 2.2 8.5 5.5 4.3 7.5 5.5 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KIK49923.1 - 2.4 8.6 10.7 1.5 9.2 1.1 2.7 1 1 2 3 3 3 0 Csm1 N-terminal domain CENP-H PF05837.12 KIK49923.1 - 2.7 8.4 6.5 5.4 7.5 6.5 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) BRE1 PF08647.11 KIK49923.1 - 4.6 7.4 10.7 5.3 7.2 1.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 KIK49923.1 - 6.3 6.0 12.8 2.5 7.3 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fungal_TACC PF12709.7 KIK49923.1 - 6.5 7.3 9.7 2.2 8.8 0.8 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Sec2p PF06428.11 KIK49923.1 - 8 6.5 10.7 2.8 8.0 2.9 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HALZ PF02183.18 KIK49923.1 - 8.1 6.8 10.0 1.7 8.9 1.6 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper FAM76 PF16046.5 KIK49923.1 - 8.5 5.6 14.2 0.13 11.6 2.7 2.2 2 0 0 2 2 2 0 FAM76 protein K-box PF01486.17 KIK49923.1 - 9 6.5 15.8 1.8 8.8 12.1 1.8 2 0 0 2 2 1 0 K-box region zf-CCHC PF00098.23 KIK49926.1 - 0.00013 21.8 1.3 0.00013 21.8 1.3 3.6 2 1 0 2 2 2 1 Zinc knuckle PolC_DP2 PF03833.13 KIK49926.1 - 0.064 11.1 3.8 0.082 10.8 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_6 PF15288.6 KIK49926.1 - 3.3 7.6 9.4 2.9 7.8 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK49926.1 - 9.5 6.2 17.5 0.064 13.1 2.7 3.3 3 0 0 3 3 3 0 Zinc knuckle DUF5095 PF17016.5 KIK49934.1 - 0.04 13.6 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) AcetylCoA_hyd_C PF13336.6 KIK49936.1 - 1.3e-40 138.8 0.0 2.9e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK49936.1 - 8.8e-24 84.6 0.0 1.6e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain PMC2NT PF08066.12 KIK49936.1 - 0.2 12.4 0.0 0.56 10.9 0.0 1.8 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Peroxidase_2 PF01328.17 KIK49938.1 - 1.7e-20 74.4 0.0 2.1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Ank_2 PF12796.7 KIK49940.1 - 1.3e-11 44.9 0.0 1.6e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK49940.1 - 2.7e-11 43.8 0.0 8.1e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK49940.1 - 4e-09 36.0 0.0 0.0094 16.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KIK49940.1 - 2.1e-08 34.3 0.0 0.00079 19.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK49940.1 - 0.0001 22.5 0.1 0.068 13.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF1843 PF08898.10 KIK49940.1 - 0.072 13.6 1.5 0.18 12.3 1.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) IBN_N PF03810.19 KIK49941.1 - 9.2e-09 35.1 0.3 3e-06 27.0 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KIK49941.1 - 0.0084 16.3 0.1 0.034 14.3 0.1 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KIK49941.1 - 0.0091 16.4 3.8 0.27 11.6 0.0 4.0 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 KIK49941.1 - 0.03 14.4 1.8 0.57 10.2 0.1 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 KIK49941.1 - 0.23 10.7 3.1 0.39 10.0 3.1 1.3 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 KIK49941.1 - 4.4 6.3 10.8 7.7 5.5 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RVP_2 PF08284.11 KIK49944.1 - 1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK49944.1 - 0.00051 20.6 0.0 0.0018 18.9 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK49944.1 - 0.0006 20.3 0.0 0.00092 19.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Parvo_NS1 PF01057.17 KIK49948.1 - 0.064 12.3 0.1 0.082 12.0 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HTH_29 PF13551.6 KIK49951.1 - 2.4e-08 33.8 0.1 5.1e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KIK49951.1 - 7.2e-08 32.0 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KIK49951.1 - 1.9e-05 25.1 0.8 0.0008 20.0 0.0 2.5 2 1 1 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KIK49951.1 - 5e-05 23.3 0.4 0.00018 21.6 0.0 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 KIK49951.1 - 0.00089 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) PAX PF00292.18 KIK49951.1 - 0.0021 18.0 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_1 PF01527.20 KIK49951.1 - 0.0033 17.7 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.15 KIK49951.1 - 0.0033 17.5 0.1 0.23 11.6 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 KIK49951.1 - 0.015 15.1 0.4 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIK49951.1 - 0.038 14.5 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_Tnp_IS630 PF01710.16 KIK49951.1 - 0.041 13.9 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 Transposase HTH_33 PF13592.6 KIK49951.1 - 0.073 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF2802 PF10975.8 KIK49951.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF4127 PF13552.6 KIK49955.1 - 0.055 12.1 0.0 0.062 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) AATase PF07247.12 KIK49955.1 - 0.085 11.4 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase B1 PF02246.15 KIK49955.1 - 0.14 12.2 0.9 8.9 6.4 0.1 2.1 2 0 0 2 2 2 0 Protein L b1 domain Cnd2 PF05786.14 KIK49958.1 - 0.3 9.7 2.8 0.39 9.3 2.8 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Toxin_13 PF07822.11 KIK49959.1 - 0.02 15.0 3.4 8.2 6.6 0.0 3.6 3 0 0 3 3 3 0 Neurotoxin B-IV-like protein DUF3713 PF12506.8 KIK49959.1 - 0.068 13.5 3.2 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) Nuclease_act PF08133.11 KIK49959.1 - 0.41 10.9 3.0 26 5.2 0.2 2.8 2 0 0 2 2 2 0 Anticodon nuclease activator family ZapB PF06005.12 KIK49959.1 - 0.48 10.9 5.0 26 5.3 0.1 3.5 3 0 0 3 3 3 0 Cell division protein ZapB PsaN PF05479.11 KIK49959.1 - 0.63 10.2 3.5 30 4.8 0.3 2.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) CxC2 PF18803.1 KIK49960.1 - 3.9e-21 75.2 0.1 5.5e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK49960.1 - 0.22 11.7 7.9 0.7 10.1 7.9 2.0 1 1 0 1 1 1 0 B-box zinc finger KDZ PF18758.1 KIK49961.1 - 1.1e-48 165.8 0.1 1.3e-48 165.6 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2353 PF09789.9 KIK49962.1 - 0.03 13.7 0.7 0.048 13.0 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TssN PF17555.2 KIK49963.1 - 0.17 11.3 5.2 0.3 10.4 5.2 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN BAF1_ABF1 PF04684.13 KIK49970.1 - 0.032 13.3 3.0 0.047 12.8 3.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Asp_protease_2 PF13650.6 KIK49975.1 - 0.00015 22.3 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK49975.1 - 0.0011 19.5 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2012 PF09430.10 KIK49978.1 - 0.0082 16.3 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Spc7 PF08317.11 KIK49979.1 - 0.011 14.6 10.7 0.018 13.9 10.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_S49_N PF08496.10 KIK49979.1 - 0.044 13.8 0.8 0.044 13.8 0.8 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK49979.1 - 0.047 14.1 12.4 0.052 14.0 9.6 2.0 1 1 1 2 2 2 0 Fez1 Transcrip_act PF04949.13 KIK49979.1 - 0.096 12.6 7.6 0.22 11.4 7.6 1.6 1 0 0 1 1 1 0 Transcriptional activator Csm1_N PF18504.1 KIK49979.1 - 0.12 12.7 13.8 0.14 12.5 5.5 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF3450 PF11932.8 KIK49979.1 - 0.14 11.5 9.5 0.13 11.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PKcGMP_CC PF16808.5 KIK49979.1 - 0.15 11.9 9.6 1.2 9.0 1.6 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 KIK49979.1 - 0.28 11.2 16.6 0.22 11.5 8.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 KIK49979.1 - 0.51 10.1 10.3 0.59 9.9 2.4 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 BRE1 PF08647.11 KIK49979.1 - 0.63 10.2 12.8 1.1 9.3 0.8 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 KIK49979.1 - 0.64 9.8 13.6 1.1 9.0 12.7 1.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KIK49979.1 - 0.86 10.1 18.1 0.084 13.4 9.9 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 KIK49979.1 - 1.6 9.1 8.2 0.55 10.6 3.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cauli_AT PF03233.13 KIK49979.1 - 2.3 8.1 6.3 0.57 10.1 1.1 2.1 1 1 1 2 2 2 0 Aphid transmission protein Sec2p PF06428.11 KIK49979.1 - 3 7.9 13.3 0.23 11.4 2.8 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Lebercilin PF15619.6 KIK49979.1 - 4.3 7.0 16.8 9.8 5.8 2.9 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 KIK49979.1 - 4.8 7.9 8.5 29 5.4 0.2 3.9 1 1 3 4 4 4 0 SlyX ADIP PF11559.8 KIK49979.1 - 6.1 6.9 13.6 5.3e+02 0.6 14.5 2.2 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KIK49979.1 - 9.2 6.4 18.3 10 6.3 3.5 1.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TSNAXIP1_N PF15739.5 KIK49980.1 - 0.038 14.4 0.6 0.083 13.3 0.6 1.6 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF745 PF05335.13 KIK49980.1 - 0.1 12.3 1.6 2.2 8.0 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Myosin_head PF00063.21 KIK49980.1 - 0.1 10.8 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AcetylCoA_hyd_C PF13336.6 KIK49981.1 - 1.6e-43 148.3 0.0 2.5e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK49981.1 - 5.5e-35 121.1 0.0 1.1e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Retrotran_gag_2 PF14223.6 KIK49982.1 - 3.1e-05 23.7 0.8 0.00018 21.2 0.4 2.3 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type YqbF PF14553.6 KIK49983.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain DUF5637 PF18687.1 KIK49984.1 - 0.093 12.7 5.3 0.14 12.2 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5637) DUF659 PF04937.15 KIK49987.1 - 0.00025 21.0 0.2 0.00055 19.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CYTL1 PF15153.6 KIK49987.1 - 0.081 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF1178 PF06676.11 KIK49987.1 - 4.1 7.8 7.4 9.1 6.7 4.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) OTT_1508_deam PF14441.6 KIK49989.1 - 8.2e-07 28.9 0.3 2e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Ank_2 PF12796.7 KIK49990.1 - 6.4e-14 52.3 20.1 0.00059 20.4 0.1 6.6 3 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK49990.1 - 3.4e-08 33.9 10.6 5.8 7.6 0.2 9.3 5 2 3 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK49990.1 - 0.0025 18.1 15.8 2.2 8.7 0.2 8.2 7 2 3 10 10 10 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK49990.1 - 0.0027 18.1 10.8 44 5.1 0.1 9.2 12 0 0 12 12 12 0 Ankyrin repeat WD40 PF00400.32 KIK49990.1 - 0.27 12.2 6.2 1.4 9.9 0.3 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Ins_P5_2-kin PF06090.12 KIK49992.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Ku_C PF03730.14 KIK49995.1 - 0.64 10.8 0.1 0.64 10.8 0.1 2.2 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm KDZ PF18758.1 KIK49998.1 - 9.8e-21 74.4 0.0 1.6e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK49998.1 - 0.0027 17.9 0.1 0.0049 17.0 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIK49998.1 - 0.021 15.0 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK49999.1 - 1.7e-15 57.2 0.1 2.9e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4253 PF14062.6 KIK50000.1 - 0.028 14.6 0.2 0.058 13.6 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4253) Choline_kinase PF01633.20 KIK50005.1 - 0.018 14.6 0.8 0.022 14.3 0.8 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-MYND PF01753.18 KIK50008.1 - 0.0048 17.0 1.9 0.013 15.6 1.9 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK50008.1 - 0.15 12.4 0.4 0.15 12.4 0.4 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding TED_complement PF07678.14 KIK50009.1 - 0.011 14.8 0.3 0.016 14.2 0.3 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF327 PF03885.13 KIK50009.1 - 0.011 15.7 0.5 0.019 14.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) TSNAXIP1_N PF15739.5 KIK50009.1 - 0.026 14.9 3.3 0.048 14.0 3.3 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus UPF0242 PF06785.11 KIK50009.1 - 0.12 12.5 7.1 0.2 11.7 7.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF648 PF04890.13 KIK50009.1 - 0.16 11.7 1.1 0.23 11.2 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF745 PF05335.13 KIK50009.1 - 0.99 9.1 6.4 16 5.1 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) INPP5B_PH PF16776.5 KIK50011.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain DUF659 PF04937.15 KIK50012.1 - 0.0019 18.0 0.1 0.002 18.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DEAD PF00270.29 KIK50014.1 - 3.7e-15 56.1 0.0 7.6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK50014.1 - 1.3e-14 54.5 0.0 3.6e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK50014.1 - 1.4e-14 54.4 0.0 2.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 KIK50015.1 - 0.018 15.2 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Dicer dimerisation domain F-box PF00646.33 KIK50021.1 - 8.8e-05 22.3 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF2025 PF09634.10 KIK50021.1 - 0.0067 16.4 0.0 1 9.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2025) DUF4171 PF13775.6 KIK50022.1 - 0.002 18.6 3.0 0.0029 18.0 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4171) DUF3459 PF11941.8 KIK50022.1 - 0.081 13.3 0.1 0.58 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Clusterin PF01093.17 KIK50022.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Clusterin KDZ PF18758.1 KIK50024.1 - 1.1e-05 25.2 0.5 1.2e-05 25.0 0.5 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MUG113 PF13455.6 KIK50025.1 - 9.6e-07 29.4 0.0 1.6e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK50025.1 - 0.00026 21.5 0.0 0.00046 20.7 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain Amidase_3 PF01520.18 KIK50026.1 - 0.0033 17.6 0.0 0.012 15.7 0.0 1.9 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Retrotrans_gag PF03732.17 KIK50027.1 - 8.8e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 KIK50030.1 - 2.5e-09 37.0 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK50030.1 - 1.2e-05 25.9 0.0 2.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK50030.1 - 5e-05 23.8 0.0 9.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3443 PF11925.8 KIK50030.1 - 0.0052 15.7 0.0 0.0069 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3443) Peptidase_A2B PF12384.8 KIK50030.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.10 KIK50030.1 - 0.09 12.6 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease CDRN PF05174.12 KIK50033.1 - 0.083 12.6 1.4 0.098 12.4 0.3 1.6 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Nit_Regul_Hom PF10126.9 KIK50034.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII IF3_N PF05198.16 KIK50034.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Glyoxalase PF00903.25 KIK50036.1 - 9.2e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIK50036.1 - 0.0024 18.1 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.22 KIK50037.1 - 4.3e-59 200.5 0.0 1.4e-52 179.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 NPL PF17800.1 KIK50038.1 - 4.3e-05 24.0 0.0 8.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin-like domain SHMT PF00464.19 KIK50038.1 - 0.022 13.4 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase JmjC PF02373.22 KIK50040.1 - 0.082 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 KIK50040.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein WD40 PF00400.32 KIK50042.1 - 3.3e-05 24.6 1.8 0.029 15.3 0.0 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50042.1 - 0.00097 19.4 0.0 3 8.2 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK50042.1 - 0.061 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 KIK50042.1 - 0.15 12.1 0.1 1 9.4 0.0 2.4 3 0 0 3 3 3 0 PQQ enzyme repeat AAA_lid_3 PF17862.1 KIK50044.1 - 0.0071 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA+ lid domain NPL PF17800.1 KIK50045.1 - 0.0032 18.0 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain WD40 PF00400.32 KIK50046.1 - 1.3e-158 510.0 38.4 3.8e-11 43.4 0.0 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50046.1 - 8.9e-44 147.7 17.7 0.0081 16.4 0.0 14.0 1 1 13 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50046.1 - 2.5e-26 92.7 6.3 1e-05 25.5 0.2 6.4 1 1 7 8 8 8 8 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK50046.1 - 4.2e-19 69.0 13.1 0.52 9.6 0.0 12.8 9 4 3 13 13 13 6 WD40-like domain Nup160 PF11715.8 KIK50046.1 - 5.5e-15 55.0 18.8 0.47 9.0 0.0 11.7 4 3 10 14 14 14 9 Nucleoporin Nup120/160 PD40 PF07676.12 KIK50046.1 - 1.5e-13 50.2 0.1 48 4.1 0.0 11.8 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50046.1 - 2.3e-12 46.5 10.0 3.4 6.5 0.0 11.9 1 1 12 13 13 13 1 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK50046.1 - 9.1e-12 44.7 21.0 8 6.5 0.0 12.6 13 0 0 13 13 13 1 Nitrous oxide reductase propeller repeat SdiA-regulated PF06977.11 KIK50046.1 - 5.9e-08 32.2 0.0 3.9 6.6 0.0 6.2 2 2 6 8 8 8 2 SdiA-regulated potato_inhibit PF00280.18 KIK50046.1 - 6.7e-07 29.9 10.9 28 5.5 0.0 10.7 6 3 6 13 13 12 0 Potato inhibitor I family NHL PF01436.21 KIK50046.1 - 6.7e-06 25.9 19.2 6.7 6.9 0.2 10.5 13 0 0 13 13 13 1 NHL repeat Str_synth PF03088.16 KIK50046.1 - 3.9e-05 23.7 0.1 8.9 6.5 0.0 6.4 7 3 2 9 9 9 1 Strictosidine synthase Imm17 PF15562.6 KIK50046.1 - 0.00085 19.1 0.0 1.5e+02 2.3 0.0 7.9 11 0 0 11 11 11 0 Immunity protein 17 PQQ_3 PF13570.6 KIK50046.1 - 0.011 16.2 36.3 20 5.8 0.2 11.4 3 2 10 13 13 13 0 PQQ-like domain LRR_10 PF18805.1 KIK50046.1 - 0.014 15.0 27.3 29 4.4 0.0 10.9 7 3 4 12 12 12 0 Leucine-rich repeat DsbC_N PF10411.9 KIK50046.1 - 0.026 14.0 18.2 1.9e+02 1.6 0.0 10.5 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus Cuticle_4 PF15955.5 KIK50046.1 - 0.41 11.4 5.2 2.6e+02 2.4 0.0 6.9 11 0 0 11 11 9 0 Cuticle protein WD40 PF00400.32 KIK50049.1 - 1.9e-07 31.7 0.7 1.2e-06 29.1 0.3 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat PD40 PF07676.12 KIK50049.1 - 0.0032 17.4 0.1 0.0045 16.9 0.1 1.3 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK50049.1 - 0.018 15.3 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SPX PF03105.19 KIK50052.1 - 2.1e-26 93.8 0.4 6e-26 92.3 0.4 1.7 1 1 0 1 1 1 1 SPX domain Peptidase_S49_N PF08496.10 KIK50053.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK50053.1 - 0.067 12.1 7.7 0.11 11.4 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KIK50053.1 - 0.31 11.4 9.7 2.1 8.7 4.3 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 KIK50053.1 - 0.34 10.2 5.4 0.51 9.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 KIK50053.1 - 0.41 10.7 10.2 0.6 10.1 5.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KIK50053.1 - 3.8 6.5 8.6 6.7 5.7 7.7 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec2p PF06428.11 KIK50053.1 - 4 7.5 10.6 0.6 10.1 2.8 2.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p TSNAXIP1_N PF15739.5 KIK50054.1 - 0.0061 16.9 1.4 0.011 16.0 1.4 1.4 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus DUF745 PF05335.13 KIK50054.1 - 0.011 15.4 2.0 2.5 7.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF648 PF04890.13 KIK50054.1 - 0.02 14.7 0.2 0.029 14.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Golgin_A5 PF09787.9 KIK50054.1 - 0.087 12.3 6.7 0.15 11.5 6.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Sec8_exocyst PF04048.14 KIK50054.1 - 0.11 12.4 2.1 0.2 11.5 1.4 1.8 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain UPF0242 PF06785.11 KIK50054.1 - 0.32 11.1 4.7 0.55 10.3 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 KIK50054.1 - 0.33 10.8 4.3 5.5 6.9 0.3 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KIK50054.1 - 9.5 6.9 8.0 21 5.8 1.0 3.2 1 1 2 3 3 3 0 SlyX SRP54_N PF02881.19 KIK50057.1 - 0.028 14.6 1.8 0.87 9.8 0.2 2.2 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain DUF2508 PF10704.9 KIK50057.1 - 0.038 14.2 1.0 0.078 13.2 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) MMR_HSR1 PF01926.23 KIK50060.1 - 5.8e-07 29.6 0.0 8.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIK50060.1 - 2.9e-06 26.7 0.1 0.014 14.5 0.1 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KIK50060.1 - 0.00027 20.4 0.0 0.001 18.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK50060.1 - 0.0016 18.4 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KIK50060.1 - 0.0038 17.4 0.0 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KIK50060.1 - 0.0059 17.0 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 KIK50060.1 - 0.0084 15.7 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KIK50060.1 - 0.036 13.8 0.0 0.042 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KIK50060.1 - 0.037 13.8 0.0 0.094 12.5 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KIK50060.1 - 0.052 13.6 0.0 5.3 7.1 0.0 2.4 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 KIK50060.1 - 0.065 12.5 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Septin NACHT PF05729.12 KIK50060.1 - 0.077 12.9 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KIK50060.1 - 0.091 12.7 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2326 PF10088.9 KIK50060.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) AAA_22 PF13401.6 KIK50060.1 - 0.099 12.9 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIK50060.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 KIK50060.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KIK50061.1 - 0.0025 17.9 0.0 0.0033 17.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase PTase_Orf2 PF11468.8 KIK50062.1 - 0.16 11.3 0.1 0.31 10.4 0.1 1.4 1 1 0 1 1 1 0 Aromatic prenyltransferase Orf2 DUF1604 PF07713.13 KIK50063.1 - 2.5e-40 136.2 1.4 2.5e-40 136.2 1.4 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KIK50063.1 - 6.4e-07 29.2 0.8 5e-06 26.3 0.4 2.6 2 0 0 2 2 2 1 G-patch domain YqgF PF14639.6 KIK50063.1 - 0.84 9.4 3.3 3.9 7.2 1.3 2.7 2 1 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 GLTP PF08718.11 KIK50067.1 - 2e-38 132.0 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) CRAL_TRIO PF00650.20 KIK50068.1 - 1.7e-05 24.6 0.2 0.017 14.8 0.1 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK50072.1 - 5.7e-30 104.1 0.1 1.9e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK50076.1 - 7.8e-34 116.7 0.1 1.2e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK50076.1 - 9.7e-09 35.3 0.5 2.3e-08 34.1 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIK50076.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK50079.1 - 3.2e-21 75.7 0.0 3.7e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK50080.1 - 0.0044 16.8 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Glyco_hydro_31 PF01055.26 KIK50084.1 - 4.7e-15 55.7 0.0 6.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK50084.1 - 2.1e-10 40.8 0.4 3.2e-10 40.2 0.4 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK50084.1 - 0.00052 20.3 1.2 0.022 15.0 0.0 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.26 KIK50085.1 - 4.4e-05 22.8 0.5 0.00028 20.2 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 NMT_C PF02799.15 KIK50086.1 - 0.099 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain KSHV_K8 PF07188.11 KIK50087.1 - 0.15 11.5 0.0 0.17 11.2 0.0 1.0 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Ribonuc_red_sm PF00268.21 KIK50089.1 - 1.1e-22 80.8 0.0 1.5e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CPSF100_C PF13299.6 KIK50090.1 - 0.042 14.0 0.3 0.095 12.9 0.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RXT2_N PF08595.11 KIK50090.1 - 0.065 13.3 5.2 0.12 12.4 5.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 KIK50090.1 - 0.8 9.5 12.7 1.8 8.4 12.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 KIK50090.1 - 1.3 7.5 4.2 1.3 7.5 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 KIK50090.1 - 2.9 6.8 14.0 5.4 5.9 14.0 1.4 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 KIK50090.1 - 5.7 4.9 18.1 11 3.9 18.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF4578 PF15147.6 KIK50091.1 - 0.96 10.3 5.2 0.74 10.7 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) Sina PF03145.16 KIK50093.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Seven in absentia protein family DEAD PF00270.29 KIK50094.1 - 1.9e-08 34.2 0.0 3.1e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK50094.1 - 0.0012 18.8 0.0 0.0047 17.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KIK50096.1 - 4.4e-26 91.6 26.0 1.4e-25 90.0 26.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Herpes_UL49_2 PF04823.12 KIK50096.1 - 0.18 12.0 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein MgtC PF02308.16 KIK50096.1 - 8.7 6.7 13.2 0.23 11.8 2.8 3.0 3 1 0 3 3 3 0 MgtC family F-box-like PF12937.7 KIK50098.1 - 7.6e-07 28.9 0.5 1.3e-06 28.1 0.5 1.4 1 0 0 1 1 1 1 F-box-like DUF2860 PF11059.8 KIK50102.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) DEC-1_N PF04625.13 KIK50107.1 - 3.8 6.4 7.5 4 6.4 7.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FixQ PF05545.11 KIK50111.1 - 2.1 8.4 3.9 1.9 8.5 0.2 2.5 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ PLAC8 PF04749.17 KIK50112.1 - 5.6e-21 75.4 11.1 7.3e-21 75.0 11.1 1.1 1 0 0 1 1 1 1 PLAC8 family G-alpha PF00503.20 KIK50115.1 - 3.1e-105 352.2 0.3 3.7e-105 352.0 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK50115.1 - 1.6e-10 40.8 0.0 9.9e-08 31.6 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK50115.1 - 0.0016 18.6 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK50115.1 - 0.027 13.8 0.0 7.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK50115.1 - 0.077 12.5 0.1 2.3 7.7 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain BTB PF00651.31 KIK50116.1 - 0.0023 18.1 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.19 KIK50116.1 - 0.091 13.2 0.4 0.19 12.2 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Goodbye PF17109.5 KIK50122.1 - 7.7e-19 68.3 0.1 1.1e-18 67.9 0.1 1.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain FliN_N PF16973.5 KIK50122.1 - 0.098 12.5 0.3 0.098 12.5 0.3 2.3 3 0 0 3 3 3 0 Flagellar motor switch protein FliN N-terminal HypD PF01924.16 KIK50122.1 - 0.2 10.7 0.4 0.37 9.8 0.4 1.4 1 1 0 1 1 1 0 Hydrogenase formation hypA family Ank_2 PF12796.7 KIK50126.1 - 1e-58 195.8 64.9 6.1e-11 42.8 1.6 6.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK50126.1 - 3.9e-45 151.6 15.4 1.2e-06 28.9 0.1 9.9 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK50126.1 - 3.1e-30 100.8 25.0 0.059 14.0 0.0 12.6 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 KIK50126.1 - 2.5e-23 81.4 39.1 0.056 13.9 0.3 11.5 12 0 0 12 12 11 9 Ankyrin repeat Ank_5 PF13857.6 KIK50126.1 - 2.4e-13 50.0 26.8 0.036 14.4 0.3 8.6 4 2 5 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.12 KIK50126.1 - 1.8e-05 24.8 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK50126.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK50126.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KIK50126.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase YajC PF02699.15 KIK50126.1 - 0.016 15.1 18.4 2.1 8.3 0.3 7.7 2 2 6 9 9 9 0 Preprotein translocase subunit DUF2075 PF09848.9 KIK50126.1 - 0.024 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KIK50126.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIK50126.1 - 0.045 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK50126.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KIK50126.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KIK50126.1 - 0.13 11.5 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 KIK50126.1 - 0.13 12.2 0.5 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KIK50130.1 - 0.0074 16.2 0.1 0.0096 15.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain YscO-like PF16789.5 KIK50131.1 - 0.002 18.2 2.0 0.0029 17.7 2.0 1.2 1 0 0 1 1 1 1 YscO-like protein DUF390 PF04094.14 KIK50131.1 - 0.0041 15.5 4.7 0.0048 15.3 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF390) Lectin_N PF03954.14 KIK50131.1 - 0.055 13.2 0.5 0.14 11.9 0.2 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 KIK50131.1 - 0.07 12.2 2.7 0.082 12.0 2.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3552 PF12072.8 KIK50132.1 - 0.007 15.8 1.1 0.011 15.2 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF390 PF04094.14 KIK50132.1 - 0.021 13.2 3.7 0.03 12.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) NACHT PF05729.12 KIK50132.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RVP_2 PF08284.11 KIK50136.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Glyoxalase PF00903.25 KIK50136.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-CCHC_4 PF14392.6 KIK50136.1 - 3.4 7.5 4.9 8.4 6.2 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle RVT_thumb PF06817.14 KIK50139.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase thumb domain DUF3804 PF12707.7 KIK50139.1 - 0.06 13.1 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) zf-CCHC PF00098.23 KIK50140.1 - 0.28 11.3 2.6 0.59 10.3 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle AcetylCoA_hydro PF02550.15 KIK50141.1 - 2.4e-28 99.5 0.0 4.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIK50141.1 - 2.1e-22 79.7 0.0 3.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain NB-ARC PF00931.22 KIK50143.1 - 0.00024 20.4 0.0 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KIK50143.1 - 0.0031 17.9 0.0 0.56 10.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK50143.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TPR_12 PF13424.6 KIK50143.1 - 0.14 12.4 0.1 3.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 KIK50145.1 - 1.7e-13 50.4 0.9 9.8e-13 48.0 0.2 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Hus1 PF04005.12 KIK50146.1 - 9.7e-12 44.6 0.3 1.1e-11 44.4 0.3 1.0 1 0 0 1 1 1 1 Hus1-like protein RVT_2 PF07727.14 KIK50148.1 - 0.003 17.2 0.0 0.0043 16.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_4 PF13495.6 KIK50149.1 - 0.019 15.4 0.1 0.032 14.7 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DRY_EERY PF09750.9 KIK50154.1 - 0.051 13.8 0.2 0.051 13.8 0.2 2.0 2 0 0 2 2 2 0 Alternative splicing regulator CxC4 PF18717.1 KIK50158.1 - 2.1e-43 147.3 0.0 3.8e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK50159.1 - 0.00023 20.9 0.8 0.00027 20.6 0.8 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase T5orf172 PF10544.9 KIK50160.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 T5orf172 domain MUG113 PF13455.6 KIK50160.1 - 0.016 15.9 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 Nucleoporin_C PF03177.14 KIK50161.1 - 0.0086 14.9 10.2 4.7 5.8 0.2 4.7 1 1 5 6 6 6 5 Non-repetitive/WGA-negative nucleoporin C-terminal DUF3024 PF11225.8 KIK50161.1 - 0.15 12.3 9.6 9.7 6.5 0.0 5.3 2 1 4 6 6 6 0 Protein of unknown function (DUF3024) Shal-type PF11601.8 KIK50161.1 - 0.27 10.8 16.7 77 3.0 0.0 8.5 10 0 0 10 10 10 0 Shal-type voltage-gated potassium channels, N-terminal PetM PF08041.11 KIK50161.1 - 3.9 7.1 14.3 39 3.9 0.0 7.2 11 0 0 11 11 11 0 PetM family of cytochrome b6f complex subunit 7 AAA_24 PF13479.6 KIK50163.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK50163.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DDE_3 PF13358.6 KIK50164.1 - 8.4e-05 22.4 0.0 9.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CART PF06373.11 KIK50165.1 - 0.22 11.8 6.7 0.62 10.3 6.7 1.7 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Vinculin PF01044.19 KIK50166.1 - 0.0074 14.6 0.1 0.011 14.1 0.1 1.2 1 0 0 1 1 1 1 Vinculin family XLF PF09302.11 KIK50166.1 - 0.1 12.7 1.3 0.18 12.0 1.3 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component F-box-like PF12937.7 KIK50168.1 - 9e-08 31.9 0.2 9e-08 31.9 0.2 2.7 3 0 0 3 3 3 1 F-box-like Ribosomal_S17e PF00833.18 KIK50171.1 - 0.017 15.0 0.4 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 Ribosomal S17 FlxA PF14282.6 KIK50171.1 - 0.031 14.3 2.6 0.049 13.6 1.9 1.7 1 1 0 1 1 1 0 FlxA-like protein EzrA PF06160.12 KIK50171.1 - 0.058 11.6 3.8 0.065 11.4 3.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Filament PF00038.21 KIK50172.1 - 1.4e-05 24.9 5.4 2e-05 24.4 5.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein K-box PF01486.17 KIK50172.1 - 0.00017 21.7 7.7 0.0032 17.6 1.2 2.8 1 1 2 3 3 3 1 K-box region DUF3450 PF11932.8 KIK50172.1 - 0.00026 20.4 6.5 0.00031 20.1 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KIK50172.1 - 0.0013 18.1 3.6 0.0015 17.9 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) ACCA PF03255.14 KIK50172.1 - 0.0014 18.6 5.7 0.067 13.1 0.8 2.1 2 0 0 2 2 2 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FliD_C PF07195.12 KIK50172.1 - 0.0027 17.2 5.0 0.0037 16.7 5.0 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Gp-FAR-1 PF05823.12 KIK50172.1 - 0.0035 17.7 2.1 0.0035 17.7 2.1 1.9 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) OmpH PF03938.14 KIK50172.1 - 0.0043 17.4 9.4 0.0059 16.9 3.6 2.0 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) DASH_Spc19 PF08287.11 KIK50172.1 - 0.0055 16.6 7.4 0.047 13.6 0.4 2.2 2 0 0 2 2 2 1 Spc19 Fez1 PF06818.15 KIK50172.1 - 0.018 15.5 6.0 0.033 14.7 6.0 1.4 1 1 0 1 1 1 0 Fez1 Tup_N PF08581.10 KIK50172.1 - 0.027 14.7 11.0 1.5 9.2 0.5 2.6 2 1 0 2 2 2 0 Tup N-terminal Cast PF10174.9 KIK50172.1 - 0.031 12.5 10.0 0.035 12.3 10.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Baculo_PEP_C PF04513.12 KIK50172.1 - 0.062 13.4 11.5 0.44 10.6 6.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 KIK50172.1 - 0.075 13.2 11.5 0.29 11.3 11.2 2.0 1 1 0 1 1 1 0 Tropomyosin like LMBR1 PF04791.16 KIK50172.1 - 0.081 11.8 3.1 0.094 11.6 3.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 KIK50172.1 - 0.084 13.3 7.9 6.4 7.2 1.1 3.3 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Yuri_gagarin PF15934.5 KIK50172.1 - 0.086 12.7 5.6 0.23 11.3 5.6 1.7 1 1 0 1 1 1 0 Yuri gagarin Prefoldin_2 PF01920.20 KIK50172.1 - 0.089 12.8 13.4 0.53 10.3 6.8 2.5 2 1 0 2 2 2 0 Prefoldin subunit Pox_A_type_inc PF04508.12 KIK50172.1 - 0.1 12.5 8.6 3.1 7.8 0.1 3.8 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat BLOC1_2 PF10046.9 KIK50172.1 - 0.17 12.2 8.4 0.5 10.7 4.0 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SPX PF03105.19 KIK50172.1 - 0.18 11.7 4.9 0.22 11.4 4.9 1.3 1 1 0 1 1 1 0 SPX domain V_ATPase_I PF01496.19 KIK50172.1 - 0.18 9.7 3.9 0.2 9.5 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOAR PF16533.5 KIK50172.1 - 0.21 11.6 4.5 3.1 7.8 4.6 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF4618 PF15397.6 KIK50172.1 - 0.29 10.5 11.3 3.6 6.9 6.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Sugarporin_N PF11471.8 KIK50172.1 - 0.35 10.8 6.5 0.97 9.4 4.0 2.7 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension Duffy_binding PF05424.11 KIK50172.1 - 0.36 10.8 5.8 4.2 7.4 5.8 1.9 1 1 0 1 1 1 0 Duffy binding domain Spc7 PF08317.11 KIK50172.1 - 0.41 9.5 10.7 0.11 11.4 5.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 KIK50172.1 - 0.46 10.5 7.8 1.7 8.7 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ArsR PF09824.9 KIK50172.1 - 0.49 10.0 3.9 5.1 6.7 0.3 2.4 2 1 0 2 2 2 0 ArsR transcriptional regulator TMF_TATA_bd PF12325.8 KIK50172.1 - 0.5 10.6 8.5 14 5.9 8.5 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 KIK50172.1 - 0.55 10.7 13.6 27 5.3 13.6 2.9 1 1 0 1 1 1 0 Cell division protein ZapB Tweety PF04906.13 KIK50172.1 - 0.6 8.7 8.0 0.53 8.9 1.9 2.0 1 1 0 2 2 2 0 Tweety TPR_MLP1_2 PF07926.12 KIK50172.1 - 0.74 9.9 14.0 0.3 11.1 6.6 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 KIK50172.1 - 0.88 9.1 13.0 1.8 8.1 8.7 2.1 1 1 1 2 2 2 0 PspA/IM30 family DUF4140 PF13600.6 KIK50172.1 - 1.2 9.6 5.7 4 7.9 1.4 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prominin PF05478.11 KIK50172.1 - 1.5 6.7 7.5 1.2 7.0 4.9 1.6 1 1 0 1 1 1 0 Prominin UPF0242 PF06785.11 KIK50172.1 - 1.8 8.6 12.0 27 4.8 12.0 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KfrA_N PF11740.8 KIK50172.1 - 2 9.2 6.4 13 6.5 2.1 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF16 PF01519.16 KIK50172.1 - 2 9.0 9.2 2 8.9 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KIK50172.1 - 2 8.6 10.2 5.3 7.2 3.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KIK50172.1 - 2.7 8.1 12.8 1.1 9.3 6.0 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KIK50172.1 - 2.8 8.6 10.1 4.5 8.0 3.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA HMMR_N PF15905.5 KIK50172.1 - 3.1 7.2 13.5 12 5.3 13.5 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Syntaxin-6_N PF09177.11 KIK50172.1 - 3.2 8.4 7.8 24 5.5 3.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CdvA PF18822.1 KIK50172.1 - 4.9 7.0 13.8 13 5.6 1.4 2.9 1 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF5595 PF18077.1 KIK50172.1 - 4.9 7.3 9.8 5.2 7.2 2.9 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5595) HalX PF08663.10 KIK50172.1 - 6.4 7.2 10.3 1.7 9.0 0.7 2.5 2 1 0 2 2 2 0 HalX domain bZIP_Maf PF03131.17 KIK50172.1 - 6.6 7.3 8.6 2.3 8.8 3.8 2.3 2 1 0 2 2 2 0 bZIP Maf transcription factor Osmo_CC PF08946.10 KIK50172.1 - 7.8 6.8 10.4 4.4 7.6 0.3 3.0 2 2 1 3 3 3 0 Osmosensory transporter coiled coil UPF0242 PF06785.11 KIK50173.1 - 0.00058 20.0 1.3 0.00072 19.7 1.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF5094 PF17015.5 KIK50173.1 - 0.02 15.0 1.0 0.026 14.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Peptidase_S46 PF10459.9 KIK50173.1 - 0.058 12.0 0.6 0.066 11.8 0.6 1.0 1 0 0 1 1 1 0 Peptidase S46 GvpL_GvpF PF06386.11 KIK50173.1 - 0.12 12.3 1.6 0.15 11.9 1.6 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4404 PF14357.6 KIK50173.1 - 0.27 11.9 8.7 0.29 11.8 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) YabA PF06156.13 KIK50173.1 - 0.47 11.1 3.5 0.76 10.4 3.5 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KIK50173.1 - 1.6 9.3 11.5 1.4 9.4 4.3 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 KIK50174.1 - 0.0046 17.0 6.1 0.0046 17.0 6.1 3.2 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.11 KIK50174.1 - 0.0059 16.0 30.2 0.3 10.4 0.5 2.4 2 0 0 2 2 2 2 Rabaptin-like protein Filament PF00038.21 KIK50174.1 - 0.0064 16.1 37.9 0.0087 15.7 1.2 3.2 2 1 0 2 2 2 1 Intermediate filament protein Cytochrom_B562 PF07361.11 KIK50174.1 - 0.018 15.7 8.4 0.018 15.7 8.4 3.7 3 1 1 4 4 3 0 Cytochrome b562 Spc7 PF08317.11 KIK50174.1 - 0.043 12.7 42.4 0.066 12.1 28.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Apolipoprotein PF01442.18 KIK50174.1 - 0.074 12.9 30.2 12 5.7 14.9 3.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Amidinotransf PF02274.17 KIK50174.1 - 0.25 10.4 8.6 0.066 12.3 5.2 1.8 1 1 1 2 2 2 0 Amidinotransferase GAS PF13851.6 KIK50174.1 - 0.36 10.1 45.9 0.91 8.8 31.7 2.8 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KIK50174.1 - 0.58 10.2 25.3 4.3 7.4 8.7 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ZnuA PF01297.17 KIK50174.1 - 1.6 8.1 14.7 4.3 6.7 9.2 2.8 2 1 1 3 3 3 0 Zinc-uptake complex component A periplasmic Atg14 PF10186.9 KIK50174.1 - 2.5 7.1 36.7 1.2 8.1 22.3 3.0 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 KIK50174.1 - 2.5 7.5 43.7 0.53 9.7 18.4 3.2 1 1 1 3 3 3 0 Golgin subfamily A member 5 FUSC PF04632.12 KIK50174.1 - 2.8 6.4 8.6 0.8 8.2 5.6 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family CCDC144C PF14915.6 KIK50174.1 - 2.9 6.9 43.3 0.064 12.4 3.7 3.3 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region FAM184 PF15665.5 KIK50174.1 - 4.6 7.0 41.2 9.2 6.0 35.0 2.9 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Bacillus_HBL PF05791.11 KIK50174.1 - 5.1 6.9 28.1 0.29 10.9 8.4 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) PilJ PF13675.6 KIK50174.1 - 6 6.9 16.1 3.8 7.6 0.2 3.5 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term ZYG-11_interact PF05884.12 KIK50174.1 - 6.3 6.1 13.8 0.54 9.6 5.3 2.4 1 1 2 3 3 3 0 Interactor of ZYG-11 DUF883 PF05957.13 KIK50174.1 - 6.5 7.4 23.3 30 5.3 6.5 4.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) T4bSS_IcmS PF12608.8 KIK50174.1 - 9.6 6.6 8.3 5 7.5 0.6 3.3 2 2 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment F-box-like PF12937.7 KIK50176.1 - 8.7e-05 22.3 1.2 0.0002 21.2 1.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KIK50179.1 - 5.3e-07 30.2 3.5 0.0034 18.2 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK50179.1 - 0.00016 21.4 0.2 0.11 12.1 0.1 2.9 3 0 0 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 KIK50179.1 - 0.00029 21.1 0.3 0.025 14.9 0.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF61 PF01886.16 KIK50183.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF61 HR1 PF02185.16 KIK50184.1 - 0.064 13.4 1.8 0.12 12.6 1.8 1.5 1 0 0 1 1 1 0 Hr1 repeat zf-CCHC PF00098.23 KIK50185.1 - 9.9e-05 22.3 3.8 0.00018 21.4 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KIK50187.1 - 4.9e-05 23.0 0.1 0.091 12.4 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DEC-1_N PF04625.13 KIK50187.1 - 0.0013 17.8 0.6 0.0015 17.6 0.6 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region WD40 PF00400.32 KIK50188.1 - 1.7e-20 73.0 2.1 2.6e-09 37.5 0.3 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50188.1 - 1.4e-08 34.9 0.0 0.0017 18.6 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50188.1 - 0.0028 17.5 0.8 0.083 12.9 0.0 2.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50188.1 - 0.0065 15.5 0.0 1.5 7.7 0.0 2.0 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5018 PF16410.5 KIK50188.1 - 0.0096 14.7 0.0 0.011 14.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5018) Gmad1 PF10647.9 KIK50188.1 - 0.012 15.4 0.1 1.4 8.7 0.0 1.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK50188.1 - 0.028 13.1 0.0 1.6 7.3 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4784 PF16023.5 KIK50188.1 - 0.13 11.2 0.0 2.4 7.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4784) WD40_like PF17005.5 KIK50188.1 - 0.18 11.1 0.0 5.7 6.2 0.0 1.9 1 1 0 2 2 2 0 WD40-like domain Proteasome_A_N PF10584.9 KIK50188.1 - 1.9 8.3 3.2 12 5.7 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Retrotran_gag_2 PF14223.6 KIK50189.1 - 2.9e-09 36.7 0.3 4e-09 36.3 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVP_2 PF08284.11 KIK50191.1 - 4.3e-05 23.3 0.9 6.2e-05 22.8 0.9 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK50191.1 - 0.00011 22.8 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK50191.1 - 0.00012 22.6 0.0 0.00028 21.4 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF3646 PF12362.8 KIK50191.1 - 0.073 13.4 0.0 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal ApbA_C PF08546.11 KIK50191.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal CENP-B_dimeris PF09026.10 KIK50192.1 - 0.011 16.1 1.6 0.02 15.3 1.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Herpes_UL32 PF06070.11 KIK50192.1 - 0.058 11.2 0.6 0.091 10.5 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF2457 PF10446.9 KIK50192.1 - 2.6 7.1 6.4 3.6 6.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1048 PF06304.11 KIK50195.1 - 0.0013 19.2 0.4 0.0031 17.9 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1048) GldM_N PF12081.8 KIK50195.1 - 0.014 15.5 3.6 0.025 14.7 3.6 1.4 1 0 0 1 1 1 0 GldM N-terminal domain TPD52 PF04201.15 KIK50195.1 - 0.031 13.9 1.2 0.061 12.9 1.2 1.5 1 0 0 1 1 1 0 Tumour protein D52 family Goodbye PF17109.5 KIK50195.1 - 0.072 13.5 0.3 0.46 11.0 0.0 2.2 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Spore_III_AB PF09548.10 KIK50195.1 - 0.081 13.0 0.8 0.19 11.8 0.4 1.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CorA PF01544.18 KIK50195.1 - 0.086 12.1 1.5 0.14 11.5 1.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein COG2 PF06148.11 KIK50195.1 - 0.09 12.9 2.0 0.39 10.8 0.6 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mer2 PF09074.10 KIK50195.1 - 0.15 11.9 4.6 0.23 11.2 4.6 1.3 1 0 0 1 1 1 0 Mer2 ParB PF08775.10 KIK50195.1 - 0.27 11.7 3.7 0.42 11.1 2.7 1.7 1 1 1 2 2 2 0 ParB family RecG_N PF17190.4 KIK50195.1 - 0.99 10.2 4.3 2.8 8.7 1.4 2.5 1 1 0 2 2 2 0 RecG N-terminal helical domain IBN_N PF03810.19 KIK50196.1 - 6e-09 35.7 0.2 1.2e-06 28.3 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KIK50196.1 - 5.2e-05 23.5 4.8 0.28 11.6 0.0 4.0 4 0 0 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 KIK50196.1 - 0.0094 16.1 0.1 0.035 14.3 0.1 2.1 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KIK50196.1 - 0.14 12.5 0.2 26 5.4 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 KIK50196.1 - 0.14 12.2 4.0 0.56 10.2 0.2 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 KIK50196.1 - 1.6 8.0 5.1 2.7 7.3 5.1 1.3 1 0 0 1 1 1 0 BUD22 TPR_12 PF13424.6 KIK50199.1 - 1.8e-34 117.9 20.8 8.2e-10 38.8 0.2 6.7 4 2 2 7 7 7 7 Tetratricopeptide repeat SNAP PF14938.6 KIK50199.1 - 3e-10 40.0 12.3 0.0019 17.7 1.6 4.6 2 1 3 5 5 5 5 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KIK50199.1 - 1.4e-06 28.0 19.5 0.12 12.3 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat RPN7 PF10602.9 KIK50199.1 - 9.3e-06 25.5 0.5 0.89 9.2 0.0 4.3 3 3 0 3 3 3 2 26S proteasome subunit RPN7 TPR_2 PF07719.17 KIK50199.1 - 0.00041 20.2 19.2 3.2 8.1 0.0 8.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK50199.1 - 0.00046 20.5 4.9 35 5.4 0.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat EzrA PF06160.12 KIK50199.1 - 0.00075 17.8 0.0 3.2 5.8 0.0 3.5 2 2 2 4 4 4 2 Septation ring formation regulator, EzrA ANAPC3 PF12895.7 KIK50199.1 - 0.0035 17.5 14.1 0.12 12.6 0.4 6.3 2 1 5 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2805 PF10985.8 KIK50199.1 - 0.0044 17.4 0.0 86 3.6 0.0 5.9 7 0 0 7 7 7 0 Protein of unknown function (DUF2805) CK2S PF15011.6 KIK50199.1 - 0.022 14.6 5.3 0.3 10.9 0.2 3.6 3 2 0 4 4 4 0 Casein Kinase 2 substrate Nexin_C PF08628.12 KIK50199.1 - 0.04 14.5 3.3 82 3.8 0.0 5.0 5 1 0 5 5 5 0 Sorting nexin C terminal UPF0147 PF03685.13 KIK50199.1 - 0.061 13.4 0.0 61 3.8 0.0 4.1 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0147) Nore1-SARAH PF16517.5 KIK50199.1 - 0.1 12.5 2.0 25 4.9 0.0 5.1 7 0 0 7 7 7 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain YfdX PF10938.8 KIK50199.1 - 0.21 11.5 7.3 5.2 7.0 0.1 4.8 4 2 0 4 4 4 0 YfdX protein Toxin_R_bind_C PF07951.12 KIK50199.1 - 0.23 11.1 0.0 38 3.8 0.0 2.9 3 0 0 3 3 3 0 Clostridium neurotoxin, C-terminal receptor binding TPR_21 PF09976.9 KIK50199.1 - 0.42 10.3 7.9 1.9 8.1 0.0 4.4 1 1 4 5 5 5 0 Tetratricopeptide repeat-like domain FUSC-like PF12805.7 KIK50199.1 - 0.42 9.6 5.7 11 5.0 0.1 3.8 4 1 0 4 4 4 0 FUSC-like inner membrane protein yccS DUF4398 PF14346.6 KIK50199.1 - 1.2 9.8 18.1 9.3 7.0 0.0 6.0 3 3 3 6 6 6 0 Domain of unknown function (DUF4398) TPR_8 PF13181.6 KIK50199.1 - 1.8 9.0 10.2 32 5.1 0.1 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Spc7 PF08317.11 KIK50200.1 - 0.0011 17.9 9.8 0.0017 17.3 9.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Peptidase_S49_N PF08496.10 KIK50200.1 - 0.0025 17.9 0.6 0.0025 17.9 0.6 1.5 2 0 0 2 2 1 1 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK50200.1 - 0.0034 17.9 8.0 0.006 17.1 8.0 1.4 1 0 0 1 1 1 1 Fez1 KASH_CCD PF14662.6 KIK50200.1 - 0.006 16.4 9.9 0.0099 15.7 9.9 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Sec2p PF06428.11 KIK50200.1 - 0.011 15.7 1.5 0.011 15.7 1.5 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Taxilin PF09728.9 KIK50200.1 - 0.022 13.9 8.6 0.033 13.4 8.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein AAA_13 PF13166.6 KIK50200.1 - 0.023 13.4 2.3 0.029 13.0 2.3 1.1 1 0 0 1 1 1 0 AAA domain HMMR_N PF15905.5 KIK50200.1 - 0.025 14.1 7.6 0.038 13.5 7.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 KIK50200.1 - 0.042 13.7 5.8 1.3 8.9 1.6 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Transcrip_act PF04949.13 KIK50200.1 - 0.12 12.3 8.0 0.28 11.1 8.0 1.6 1 0 0 1 1 1 0 Transcriptional activator Phage_GP20 PF06810.11 KIK50200.1 - 0.2 11.4 8.3 1.3 8.8 1.7 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Csm1_N PF18504.1 KIK50200.1 - 0.29 11.5 12.7 0.21 11.9 4.2 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain MCU PF04678.13 KIK50200.1 - 0.5 10.4 2.1 0.86 9.7 2.1 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1664 PF07889.12 KIK50200.1 - 0.54 10.3 2.1 1.1 9.3 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 KIK50200.1 - 0.59 10.2 15.1 2 8.5 6.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 KIK50200.1 - 1 9.7 7.3 6.7 7.1 7.3 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.6 KIK50200.1 - 1.1 8.9 13.9 1.8 8.2 13.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KIK50200.1 - 1.2 9.2 9.7 0.38 10.8 6.6 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FtsX_ECD PF18075.1 KIK50200.1 - 1.4 9.6 3.9 2.8 8.6 2.8 2.0 1 1 0 1 1 1 0 FtsX extracellular domain DUF4407 PF14362.6 KIK50200.1 - 1.6 8.0 8.2 2.4 7.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KIK50200.1 - 1.7 7.9 10.0 0.097 12.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KIK50200.1 - 2 8.6 18.6 20 5.3 4.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 KIK50200.1 - 6 7.0 12.9 4.8 7.3 1.0 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.19 KIK50200.1 - 6.2 4.6 5.2 8.1 4.2 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF648 PF04890.13 KIK50201.1 - 0.044 13.5 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) HR1 PF02185.16 KIK50201.1 - 6.7 6.9 8.7 0.93 9.7 2.3 2.3 2 1 0 2 2 2 0 Hr1 repeat WD40 PF00400.32 KIK50204.1 - 1.2e-126 408.9 31.0 1.3e-10 41.7 0.0 12.2 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50204.1 - 1.7e-43 146.8 7.1 0.0014 18.9 0.1 12.0 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50204.1 - 9.2e-22 77.9 1.6 0.00011 22.1 0.0 6.0 1 1 5 7 7 7 7 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50204.1 - 3.5e-19 68.8 10.5 0.78 8.3 0.1 10.8 6 2 3 11 11 11 8 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50204.1 - 2.2e-17 63.3 9.1 0.063 12.6 0.0 9.8 8 3 2 10 10 10 6 WD40-like domain Ge1_WD40 PF16529.5 KIK50204.1 - 1.2e-14 54.1 4.1 1.6 7.6 0.0 10.9 1 1 9 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK50204.1 - 1.3e-14 53.7 0.9 4.9 7.2 0.0 11.0 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK50204.1 - 2.2e-12 46.7 11.6 4.2 7.3 0.0 10.1 11 0 0 11 11 10 1 Nitrous oxide reductase propeller repeat potato_inhibit PF00280.18 KIK50204.1 - 2.4e-08 34.5 9.4 47 4.8 0.0 10.0 8 2 4 12 12 11 0 Potato inhibitor I family Imm17 PF15562.6 KIK50204.1 - 2.1e-06 27.5 0.0 45 4.0 0.0 8.6 11 0 0 11 11 11 0 Immunity protein 17 Peptidase_S9_N PF02897.15 KIK50204.1 - 4.7e-06 25.7 4.1 9.6 4.9 0.0 7.5 2 2 5 8 8 8 0 Prolyl oligopeptidase, N-terminal beta-propeller domain NHL PF01436.21 KIK50204.1 - 5.5e-05 23.0 12.3 26 5.1 0.0 9.2 12 0 0 12 12 10 0 NHL repeat Me-amine-dh_H PF06433.11 KIK50204.1 - 7e-05 21.8 0.1 10 4.9 0.0 5.8 3 3 2 7 7 7 0 Methylamine dehydrogenase heavy chain (MADH) LRR_10 PF18805.1 KIK50204.1 - 7e-05 22.4 26.4 15 5.4 0.2 10.3 8 2 3 11 11 11 0 Leucine-rich repeat DUF1513 PF07433.11 KIK50204.1 - 0.00036 19.7 23.7 1.2 8.1 0.8 7.4 1 1 7 8 8 8 2 Protein of unknown function (DUF1513) TTR-52 PF01060.23 KIK50204.1 - 0.00038 21.1 1.9 22 5.8 0.0 6.0 3 2 5 8 8 7 0 Transthyretin-like family DUF4988 PF16378.5 KIK50204.1 - 0.00066 19.4 14.8 0.026 14.2 2.2 5.9 1 1 5 6 6 6 1 Domain of unknown function Str_synth PF03088.16 KIK50204.1 - 0.0021 18.1 0.0 68 3.7 0.0 5.9 5 1 3 8 8 8 0 Strictosidine synthase COPI_C PF06957.11 KIK50204.1 - 0.0079 15.0 0.0 37 2.9 0.0 5.3 4 3 1 6 6 6 0 Coatomer (COPI) alpha subunit C-terminus AHJR-like PF18743.1 KIK50204.1 - 0.016 14.7 0.2 99 2.5 0.0 4.5 3 1 2 5 5 5 0 REase_AHJR-like Coatomer_WDAD PF04053.14 KIK50204.1 - 0.077 12.0 7.6 1.9 7.4 0.9 3.8 1 1 0 3 3 3 0 Coatomer WD associated region DUF3748 PF12566.8 KIK50204.1 - 0.1 12.5 6.5 11 6.0 0.0 6.1 7 1 1 9 9 8 0 Protein of unknown function (DUF3748) HPS3_N PF14761.6 KIK50204.1 - 0.16 11.4 0.1 10 5.6 0.0 3.8 3 2 5 8 8 7 0 Hermansky-Pudlak syndrome 3 DsbC_N PF10411.9 KIK50204.1 - 0.46 10.0 14.0 1.4e+02 2.0 0.0 8.3 12 0 0 12 12 11 0 Disulfide bond isomerase protein N-terminus DUF4995 PF16386.5 KIK50205.1 - 0.022 14.7 0.3 0.029 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function Plavaka PF18759.1 KIK50210.1 - 9.4e-61 205.8 0.0 1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK50211.1 - 2.9e-15 56.3 0.0 3.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase TFA2_Winged_2 PF18121.1 KIK50213.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 EPTP PF03736.17 KIK50214.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 EPTP domain Peptidase_C48 PF02902.19 KIK50215.1 - 4.4e-23 82.2 1.2 7e-23 81.6 1.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Poty_PP PF08440.10 KIK50218.1 - 0.19 10.8 0.0 0.19 10.8 0.0 1.0 1 0 0 1 1 1 0 Potyviridae polyprotein AMP-binding PF00501.28 KIK50219.1 - 1.1e-16 60.4 0.3 1.3e-16 60.2 0.3 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIK50220.1 - 6.6e-85 285.5 0.0 5.9e-30 104.3 0.0 6.6 6 1 0 6 6 6 6 Condensation domain AMP-binding PF00501.28 KIK50220.1 - 2.1e-76 257.2 0.0 4.4e-57 193.6 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KIK50220.1 - 7.1e-35 119.2 3.4 1e-08 35.4 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIK50220.1 - 2.5e-09 38.0 0.4 0.002 19.0 0.0 3.5 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KIK50220.1 - 0.026 13.2 0.0 0.29 9.8 0.0 2.1 2 0 0 2 2 2 0 Transferase family AAA_21 PF13304.6 KIK50221.1 - 0.0011 18.9 0.5 0.0012 18.7 0.5 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system OTT_1508_deam PF14441.6 KIK50222.1 - 0.00052 20.0 0.3 0.0011 18.9 0.3 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase CDC45 PF02724.14 KIK50222.1 - 0.0055 15.1 3.8 0.0075 14.6 3.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 KIK50222.1 - 0.38 8.8 12.1 0.54 8.3 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-RVT PF13966.6 KIK50223.1 - 0.017 15.8 0.7 0.026 15.2 0.7 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RNase_H PF00075.24 KIK50224.1 - 0.032 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 RNase H MGAT2 PF05060.14 KIK50224.1 - 0.064 12.3 0.0 0.072 12.1 0.0 1.0 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) RVT_1 PF00078.27 KIK50225.1 - 1.2e-06 28.3 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF717 PF05338.12 KIK50225.1 - 0.063 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF717) DUF5427 PF10310.9 KIK50229.1 - 0.053 12.5 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4452 PF14618.6 KIK50229.1 - 0.85 9.5 9.1 1.3 8.8 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DDE_Tnp_4 PF13359.6 KIK50231.1 - 0.00039 20.1 0.0 0.012 15.3 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 KIK50232.1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK50232.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 KIK50233.1 - 3.4e-16 59.2 0.3 2.6e-15 56.3 0.2 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIK50233.1 - 0.0014 18.4 0.1 0.01 15.6 0.0 2.4 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type Aldo_ket_red PF00248.21 KIK50236.1 - 3.9e-15 55.8 0.3 1.8e-06 27.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family EB PF01683.18 KIK50237.1 - 0.35 11.2 8.3 0.4 11.0 6.4 2.1 1 1 1 2 2 2 0 EB module YcgR_2 PF12945.7 KIK50240.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein YcgR RicinB_lectin_2 PF14200.6 KIK50241.1 - 0.023 15.4 0.7 0.049 14.4 0.7 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF4201 PF13870.6 KIK50242.1 - 0.00048 19.9 6.1 0.00056 19.7 6.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) GAS PF13851.6 KIK50242.1 - 0.0063 15.9 7.6 0.0092 15.3 7.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding kleA_kleC PF17383.2 KIK50242.1 - 0.035 14.4 0.7 0.049 14.0 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A UPF0242 PF06785.11 KIK50242.1 - 0.044 13.9 5.7 0.051 13.7 5.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KIK50242.1 - 0.045 14.4 5.5 0.06 14.0 5.5 1.3 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 KIK50242.1 - 0.57 10.0 9.8 0.21 11.4 5.9 1.9 1 1 1 2 2 2 0 Septum formation initiator FtsL PF04999.13 KIK50242.1 - 2.5 8.2 5.7 6.7 6.8 5.7 1.8 1 1 0 1 1 1 0 Cell division protein FtsL SWIRM-assoc_1 PF16495.5 KIK50242.1 - 8.6 6.4 11.8 5.8 7.0 1.8 2.1 1 1 1 2 2 2 0 SWIRM-associated region 1 JmjC PF02373.22 KIK50244.1 - 2e-06 28.2 0.0 2.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KIK50245.1 - 0.0059 16.5 0.2 0.018 15.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like adh_short PF00106.25 KIK50246.1 - 1.7e-23 83.1 0.2 5.7e-23 81.4 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK50246.1 - 1.6e-15 57.3 0.1 4.6e-15 55.8 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK50246.1 - 1.3e-08 35.0 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK50246.1 - 0.0013 17.9 0.1 0.0023 17.1 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KIK50246.1 - 0.0044 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIK50246.1 - 0.016 15.8 0.1 0.038 14.6 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIK50246.1 - 0.038 13.5 0.0 0.077 12.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KIK50246.1 - 0.071 13.6 0.0 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KIK50246.1 - 0.12 13.0 0.1 0.8 10.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK50246.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IL4 PF00727.18 KIK50253.1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Interleukin 4 DUF485 PF04341.12 KIK50256.1 - 0.02 14.9 0.4 0.025 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DEAD PF00270.29 KIK50257.1 - 0.00028 20.7 0.0 0.0003 20.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK50257.1 - 0.00034 20.7 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Microtub_bd PF16796.5 KIK50257.1 - 0.056 13.4 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Microtubule binding T2SSE PF00437.20 KIK50257.1 - 0.07 12.2 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KIK50257.1 - 0.074 12.8 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KIK50257.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 KIK50258.1 - 4.2e-05 23.6 0.0 5.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2063 PF09836.9 KIK50258.1 - 0.055 13.7 0.0 0.069 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative DNA-binding domain DEAD PF00270.29 KIK50258.1 - 0.24 11.1 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase UPF0239 PF06783.11 KIK50262.1 - 0.16 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) WD40 PF00400.32 KIK50264.1 - 7.4e-120 387.4 71.7 8e-11 42.3 1.7 12.4 13 0 0 13 13 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50264.1 - 4.1e-34 116.7 16.3 0.0044 17.3 0.2 11.7 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50264.1 - 9.7e-21 74.4 13.1 0.00081 18.8 0.0 8.5 1 1 8 10 10 10 8 WD40-like domain Frtz PF11768.8 KIK50264.1 - 9.1e-09 34.2 1.4 6.1 5.0 0.0 8.3 1 1 7 9 9 9 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK50264.1 - 8.5e-06 26.1 7.0 0.48 11.0 0.1 7.5 8 1 1 9 9 9 1 PQQ-like domain DUF727 PF05303.12 KIK50264.1 - 8.8e-05 22.5 1.3 14 5.8 0.0 5.8 4 2 2 6 6 6 0 Protein of unknown function (DUF727) DUF4242 PF14026.6 KIK50264.1 - 0.0013 18.9 0.0 58 4.0 0.0 5.7 6 1 1 7 7 7 0 Protein of unknown function (DUF4242) Ge1_WD40 PF16529.5 KIK50264.1 - 0.005 15.8 17.0 1.2 8.0 3.0 7.7 1 1 8 9 9 9 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK50264.1 - 0.013 15.4 0.1 2.7e+02 1.8 0.0 6.1 7 0 0 7 7 7 0 PQQ enzyme repeat Kelch_6 PF13964.6 KIK50264.1 - 0.015 15.6 11.1 3.6 8.0 0.0 6.2 7 0 0 7 7 6 0 Kelch motif DUF1258 PF06869.12 KIK50264.1 - 0.018 14.5 0.2 15 4.9 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1258) HATPase_c_2 PF13581.6 KIK50264.1 - 0.068 13.1 0.0 0.94 9.4 0.0 2.9 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain Robl_LC7 PF03259.17 KIK50264.1 - 0.16 11.8 0.5 7.2 6.5 0.0 3.9 5 0 0 5 5 4 0 Roadblock/LC7 domain AHJR-like PF18743.1 KIK50264.1 - 0.19 11.3 0.0 18 4.9 0.0 2.8 1 1 0 2 2 2 0 REase_AHJR-like ObR_Ig PF18589.1 KIK50264.1 - 0.24 11.8 1.0 45 4.5 0.0 3.8 4 1 1 5 5 5 0 Obesity receptor immunoglobulin like domain Coat_X PF07552.11 KIK50264.1 - 0.79 9.6 2.2 11 5.9 0.1 3.3 3 0 0 3 3 3 0 Spore Coat Protein X and V domain PD40 PF07676.12 KIK50264.1 - 1.1 9.3 16.0 44 4.2 0.0 8.6 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat AcetylCoA_hyd_C PF13336.6 KIK50266.1 - 1.2e-36 126.0 0.0 1.3e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK50267.1 - 1.7e-63 209.1 29.8 4.5e-11 43.1 0.6 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50267.1 - 1.5e-21 76.5 8.0 0.00019 21.6 0.1 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50267.1 - 8.3e-12 45.0 5.4 0.0091 15.4 0.0 4.8 1 1 4 5 5 5 4 WD40-like domain Cytochrom_D1 PF02239.16 KIK50267.1 - 4.4e-07 28.8 3.2 1e-05 24.3 0.2 3.0 1 1 0 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.11 KIK50267.1 - 1.7e-06 28.1 0.2 0.00097 19.1 0.1 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK50267.1 - 1.8e-06 26.6 0.7 1.9 6.7 0.0 4.3 1 1 2 4 4 4 4 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK50267.1 - 1.8e-06 27.1 4.1 0.89 8.5 0.1 4.7 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK50267.1 - 0.0014 17.4 7.3 0.08 11.6 0.1 4.1 1 1 4 5 5 5 2 Nucleoporin Nup120/160 AbiJ_NTD5 PF18865.1 KIK50267.1 - 0.052 13.3 0.0 4.7 7.1 0.0 3.3 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 PD40 PF07676.12 KIK50267.1 - 0.12 12.3 3.0 17 5.5 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK50267.1 - 0.22 11.5 1.5 30 4.8 0.0 4.3 6 0 0 6 6 6 0 PQQ enzyme repeat AcetylCoA_hydro PF02550.15 KIK50269.1 - 3.3e-30 105.5 0.0 6.2e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIK50269.1 - 9.2e-09 35.4 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PhyH PF05721.13 KIK50270.1 - 2.8e-24 86.6 0.0 3.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KIK50270.1 - 0.0017 18.7 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase GMC_oxred_N PF00732.19 KIK50271.1 - 3.5e-62 210.4 0.0 6.4e-62 209.6 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK50271.1 - 6.6e-31 107.8 0.0 1.1e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK50271.1 - 0.00024 20.3 0.6 0.32 10.0 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK50271.1 - 0.00025 20.2 0.6 0.0004 19.5 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK50271.1 - 0.0005 19.8 0.0 0.09 12.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KIK50271.1 - 0.0075 15.5 0.2 0.016 14.4 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK50271.1 - 0.032 13.4 0.0 0.21 10.8 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK50271.1 - 0.035 14.3 0.1 0.099 12.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KIK50272.1 - 4.6e-39 132.9 37.1 1.1e-12 48.4 3.6 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK50272.1 - 6.5e-32 109.5 13.5 1.3e-06 28.8 0.1 8.2 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK50272.1 - 1.8e-27 92.3 20.9 0.0091 16.4 0.1 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank PF00023.30 KIK50272.1 - 2.3e-23 81.5 38.7 0.029 14.8 0.3 9.7 9 1 1 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KIK50272.1 - 2.3e-12 46.9 22.3 0.00019 21.7 1.1 6.6 2 1 6 8 8 8 5 Ankyrin repeats (many copies) eIF-5a PF01287.20 KIK50272.1 - 0.0033 17.5 0.7 25 5.1 0.0 4.1 4 1 0 4 4 4 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Thioredoxin_7 PF13899.6 KIK50272.1 - 0.05 13.8 3.6 48 4.2 0.0 5.0 6 0 0 6 6 6 0 Thioredoxin-like DUF240 PF03086.14 KIK50272.1 - 0.053 13.4 0.0 52 3.8 0.0 4.1 3 2 2 5 5 5 0 Domain of unknown function (DUF240) AlaE PF06610.13 KIK50272.1 - 0.12 12.4 0.4 10 6.1 0.0 3.2 2 1 2 5 5 5 0 L-alanine exporter Borealin PF10512.9 KIK50272.1 - 0.12 12.3 0.2 1.2e+02 2.7 0.0 3.8 3 2 1 4 4 4 0 Cell division cycle-associated protein 8 YajC PF02699.15 KIK50272.1 - 0.27 11.1 6.1 25 4.9 0.1 5.4 2 1 4 7 7 7 0 Preprotein translocase subunit MFS_1 PF07690.16 KIK50273.1 - 1.5e-32 112.9 16.7 1.5e-32 112.9 16.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 KIK50273.1 - 0.09 13.1 0.0 0.09 13.1 0.0 3.3 3 2 1 4 4 4 0 Domain of unknown function (DUF1772) DUF4094 PF13334.6 KIK50273.1 - 0.58 10.6 2.2 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DoxX_2 PF13564.6 KIK50275.1 - 0.37 10.9 5.8 2.3 8.4 6.1 2.1 1 1 0 1 1 1 0 DoxX-like family MYT1 PF08474.11 KIK50278.1 - 0.18 11.7 4.7 0.16 11.9 3.0 1.7 2 0 0 2 2 2 0 Myelin transcription factor 1 DDE_3 PF13358.6 KIK50279.1 - 0.00011 22.0 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.16 KIK50280.1 - 3.3e-40 138.1 44.3 1.7e-39 135.7 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK50280.1 - 1.9e-13 50.1 7.4 1.9e-13 50.1 7.4 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK50280.1 - 3.2e-11 42.4 2.0 5.2e-11 41.7 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIK50280.1 - 3.9e-06 26.4 4.7 3.9e-06 26.4 4.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF308 PF03729.13 KIK50282.1 - 4.2 7.8 9.0 0.92 9.9 1.4 2.7 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Uricase PF01014.18 KIK50284.1 - 1.3e-70 235.7 0.0 6.1e-37 126.8 0.1 2.0 2 0 0 2 2 2 2 Uricase Pectinesterase PF01095.19 KIK50285.1 - 3.9e-35 121.0 0.2 1.1e-30 106.4 0.6 2.1 2 0 0 2 2 2 2 Pectinesterase GET2 PF08690.10 KIK50286.1 - 0.00045 20.0 0.6 0.33 10.6 0.1 2.5 2 0 0 2 2 2 2 GET complex subunit GET2 NPV_P10 PF05531.12 KIK50286.1 - 0.038 14.4 3.6 12 6.4 0.0 4.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ZZ PF00569.17 KIK50286.1 - 0.052 13.4 48.3 0.1 12.4 7.2 4.6 4 0 0 4 4 4 0 Zinc finger, ZZ type Gon7 PF08738.10 KIK50286.1 - 0.091 12.8 2.0 0.23 11.6 2.0 1.7 1 0 0 1 1 1 0 Gon7 family NPV_P10 PF05531.12 KIK50287.1 - 0.27 11.7 0.0 0.27 11.7 0.0 4.0 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF4972 PF16342.5 KIK50287.1 - 0.76 9.5 2.9 28 4.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) ZZ PF00569.17 KIK50287.1 - 2.8 7.8 18.9 0.084 12.7 7.2 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type ETX_MTX2 PF03318.13 KIK50289.1 - 4.6e-09 36.4 11.9 6.5e-09 35.9 11.9 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Jacalin PF01419.17 KIK50289.1 - 2.8e-07 30.5 0.2 9.1e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Jacalin-like lectin domain DUF4232 PF14016.6 KIK50289.1 - 0.021 15.0 0.2 0.053 13.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) GMC_oxred_C PF05199.13 KIK50290.1 - 1.3e-31 110.0 0.0 2.3e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK50290.1 - 6.7e-23 81.5 0.1 9.4e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase F-box-like PF12937.7 KIK50293.1 - 0.00036 20.4 0.4 0.001 18.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like CBM32 PF18344.1 KIK50294.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module family 32 PIF1 PF05970.14 KIK50296.1 - 2e-06 27.3 0.1 2.1e-06 27.2 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KIK50296.1 - 0.00017 22.0 0.0 0.00018 21.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK50296.1 - 0.00065 19.5 0.0 0.00065 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK50296.1 - 0.014 15.4 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_capsid PF01003.19 KIK50296.1 - 0.092 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Flavivirus capsid protein C AAA_16 PF13191.6 KIK50296.1 - 0.17 12.3 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Suf PF05843.14 KIK50299.1 - 1.5e-70 238.5 8.4 1.1e-68 232.5 0.0 4.3 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KIK50299.1 - 6.2e-07 29.7 2.3 0.69 10.9 0.0 5.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK50299.1 - 7.3e-07 29.6 1.4 0.35 11.4 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK50299.1 - 0.0015 19.1 0.2 4.2 8.1 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 KIK50299.1 - 0.11 11.7 9.6 0.11 11.7 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Skp1 PF01466.19 KIK50301.1 - 6.5e-26 90.2 0.2 6.5e-26 90.2 0.2 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK50301.1 - 2.9e-20 72.2 0.1 1.2e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 KIK50301.1 - 0.0049 17.1 0.1 0.038 14.2 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain SERTA PF06031.13 KIK50301.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 SERTA motif DUF615 PF04751.14 KIK50301.1 - 0.1 12.6 0.1 0.49 10.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Cyclin_N PF00134.23 KIK50302.1 - 9.5e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK50302.1 - 1.1e-08 35.6 0.0 1.2e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin Abhydrolase_1 PF00561.20 KIK50303.1 - 3.8e-12 46.4 0.0 1.5e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK50303.1 - 4.2e-06 27.5 0.3 5.8e-06 27.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK50303.1 - 0.0001 21.7 0.0 0.00063 19.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIK50303.1 - 0.00099 17.9 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 KIK50303.1 - 0.029 14.2 0.0 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KIK50303.1 - 0.034 14.1 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KIK50303.1 - 0.04 13.4 0.0 0.17 11.3 0.0 2.0 2 1 1 3 3 3 0 Prolyl oligopeptidase family F-box-like PF12937.7 KIK50305.1 - 0.11 12.3 1.7 4.8 7.1 0.0 3.6 4 0 0 4 4 4 0 F-box-like DDE_Tnp_1_6 PF13751.6 KIK50305.1 - 0.68 10.2 5.5 0.44 10.8 1.7 2.4 1 1 1 2 2 2 0 Transposase DDE domain Hormone_2 PF00123.20 KIK50306.1 - 0.11 12.4 2.9 23 5.0 0.1 3.6 3 0 0 3 3 3 0 Peptide hormone zf-MYND PF01753.18 KIK50307.1 - 4.3e-09 36.3 17.2 1.4e-08 34.7 17.2 1.9 1 1 0 1 1 1 1 MYND finger HD_6 PF18019.1 KIK50307.1 - 0.0061 16.7 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 HD domain zf-C6H2 PF15801.5 KIK50307.1 - 0.58 10.5 11.1 2.3 8.6 11.1 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RnlB_antitoxin PF15933.5 KIK50311.1 - 0.068 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Antitoxin to bacterial toxin RNase LS or RnlA WD40 PF00400.32 KIK50315.1 - 1.9e-21 76.0 6.7 2.1e-09 37.8 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50315.1 - 1.9e-07 31.3 0.0 0.027 14.7 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK50315.1 - 0.0011 18.0 0.0 0.24 10.3 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK50315.1 - 0.0033 16.8 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 2 WD40-like domain Frtz PF11768.8 KIK50315.1 - 0.0042 15.5 0.0 0.27 9.5 0.0 2.0 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF4784 PF16023.5 KIK50315.1 - 0.03 13.3 0.0 0.068 12.1 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4784) PD40 PF07676.12 KIK50315.1 - 0.07 13.1 0.9 0.82 9.7 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Retrotrans_gag PF03732.17 KIK50316.1 - 8.8e-07 29.1 0.1 2e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK50316.1 - 5.3e-05 23.1 3.8 0.0001 22.2 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF327 PF03885.13 KIK50317.1 - 0.0084 16.1 0.4 0.015 15.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF327) TSNAXIP1_N PF15739.5 KIK50317.1 - 0.013 15.9 2.0 0.025 15.0 2.0 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF648 PF04890.13 KIK50317.1 - 0.023 14.4 0.6 0.036 13.8 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) TED_complement PF07678.14 KIK50317.1 - 0.053 12.5 0.2 0.074 12.1 0.2 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF745 PF05335.13 KIK50317.1 - 0.23 11.2 4.9 6.4 6.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 KIK50317.1 - 0.29 11.2 5.2 0.46 10.6 5.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KIK50317.1 - 9.1 7.0 10.1 8.8 7.0 0.4 3.2 2 1 1 3 3 3 0 SlyX PKcGMP_CC PF16808.5 KIK50318.1 - 0.004 17.0 7.8 0.78 9.6 0.3 3.6 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK50318.1 - 0.017 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_13 PF13166.6 KIK50318.1 - 0.028 13.1 1.0 0.038 12.7 1.0 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KIK50318.1 - 0.036 12.9 7.4 0.056 12.3 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1635 PF07795.11 KIK50318.1 - 0.075 12.9 1.5 0.24 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Fez1 PF06818.15 KIK50318.1 - 0.28 11.6 6.6 0.36 11.3 5.4 1.7 1 1 1 2 2 2 0 Fez1 TMF_DNA_bd PF12329.8 KIK50318.1 - 0.28 11.2 8.4 0.66 10.0 3.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KIK50318.1 - 0.34 11.3 7.7 0.8 10.1 0.6 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF641 PF04859.12 KIK50318.1 - 0.74 10.2 5.2 0.99 9.7 0.9 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.6 KIK50318.1 - 0.86 9.2 9.9 3.2 7.4 1.4 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 KIK50318.1 - 2.3 8.0 12.0 4.3 7.1 3.1 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Sec2p PF06428.11 KIK50318.1 - 6.6 6.8 7.1 1.9 8.5 1.1 2.5 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p TMEM107 PF14995.6 KIK50321.1 - 0.0057 17.1 2.6 0.019 15.4 1.8 1.9 2 0 0 2 2 2 1 Transmembrane protein Jacalin PF01419.17 KIK50325.1 - 5.6e-25 87.8 0.0 3.1e-07 30.4 0.0 3.6 3 0 0 3 3 3 3 Jacalin-like lectin domain ETX_MTX2 PF03318.13 KIK50325.1 - 1.8e-05 24.7 2.7 2.8e-05 24.0 2.7 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 PUA_3 PF17785.1 KIK50325.1 - 0.0031 17.3 0.2 5.1 7.0 0.0 3.3 3 0 0 3 3 3 2 PUA-like domain Polyketide_cyc2 PF10604.9 KIK50325.1 - 0.045 14.0 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Translin PF01997.16 KIK50327.1 - 0.044 13.8 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 Translin family RVT_thumb PF06817.14 KIK50328.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVT_3 PF13456.6 KIK50329.1 - 0.21 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like AcetylCoA_hyd_C PF13336.6 KIK50332.1 - 2.8e-11 43.6 0.0 3.1e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK50333.1 - 1.7e-117 379.9 76.9 1.3e-10 41.7 0.0 12.0 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50333.1 - 9.9e-34 115.5 18.5 0.0017 18.6 0.0 11.4 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50333.1 - 1.2e-16 60.9 15.3 0.0019 17.6 0.5 6.9 1 1 5 7 7 7 4 WD40-like domain eIF2A PF08662.11 KIK50333.1 - 2.6e-14 53.5 1.5 0.015 15.2 0.0 5.1 1 1 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK50333.1 - 4.3e-11 41.8 3.1 2.7 6.2 0.0 8.0 2 2 6 10 10 10 4 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK50333.1 - 2.8e-09 37.2 16.2 0.44 11.1 0.0 9.6 11 1 1 12 12 11 2 PQQ-like domain PQQ_2 PF13360.6 KIK50333.1 - 4.1e-09 36.4 17.0 8.5e-05 22.3 5.4 5.6 1 1 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK50333.1 - 7.6e-09 34.6 14.9 0.007 14.9 0.2 4.7 2 2 2 5 5 5 5 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 KIK50333.1 - 2.1e-07 30.2 0.9 1.1 8.0 0.0 5.2 3 2 6 9 9 9 3 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 KIK50333.1 - 2.3e-06 26.6 16.8 0.68 8.5 0.1 7.4 2 2 5 8 8 8 3 Nucleoporin Nup120/160 SecA_PP_bind PF01043.20 KIK50333.1 - 7.8e-06 26.5 0.1 34 5.2 0.0 7.5 6 2 4 10 10 9 0 SecA preprotein cross-linking domain Ge1_WD40 PF16529.5 KIK50333.1 - 1.4e-05 24.3 19.8 4.4 6.2 0.0 8.8 2 2 7 9 9 9 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KIK50333.1 - 7e-05 22.0 3.8 0.64 9.0 0.1 4.6 1 1 2 5 5 5 2 VID27 C-terminal WD40-like domain Kelch_6 PF13964.6 KIK50333.1 - 0.00031 20.9 14.1 0.26 11.7 0.2 7.0 8 0 0 8 8 7 1 Kelch motif PQQ PF01011.21 KIK50333.1 - 0.00088 19.1 6.6 3.4 7.8 0.0 7.6 10 0 0 10 10 10 1 PQQ enzyme repeat CHAP PF05257.16 KIK50333.1 - 0.006 17.1 15.9 8.2 7.1 0.1 6.5 1 1 5 6 6 6 0 CHAP domain AbiJ_NTD5 PF18865.1 KIK50333.1 - 0.026 14.3 0.1 4.1 7.3 0.0 3.7 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 HATPase_c_2 PF13581.6 KIK50333.1 - 0.031 14.2 0.0 1.8 8.5 0.0 3.5 3 2 0 3 3 3 0 Histidine kinase-like ATPase domain Robl_LC7 PF03259.17 KIK50333.1 - 0.032 14.0 0.1 3.5 7.5 0.0 3.4 3 0 0 3 3 3 0 Roadblock/LC7 domain LRR_10 PF18805.1 KIK50333.1 - 0.042 13.5 5.7 4.3 7.0 0.0 6.2 6 3 1 7 7 7 0 Leucine-rich repeat GTP_EFTU PF00009.27 KIK50333.1 - 0.05 13.1 1.4 2.4 7.6 0.1 3.9 3 1 0 4 4 4 0 Elongation factor Tu GTP binding domain Coat_X PF07552.11 KIK50333.1 - 0.92 9.4 10.3 2.1 8.2 0.1 4.7 6 0 0 6 6 5 0 Spore Coat Protein X and V domain DUF2935 PF11155.8 KIK50334.1 - 0.25 11.7 2.1 8.2 6.8 2.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ApoLp-III PF07464.11 KIK50334.1 - 0.59 10.2 7.5 1.5 8.9 0.1 3.0 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Cnl2_NKP2 PF09447.10 KIK50336.1 - 0.0082 16.3 0.5 0.016 15.3 0.5 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein WD40 PF00400.32 KIK50337.1 - 6.8e-117 378.0 85.6 1.3e-10 41.7 1.8 12.5 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50337.1 - 3.6e-37 126.5 23.9 0.0021 18.3 0.1 11.9 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50337.1 - 6.5e-19 68.4 16.1 0.03 13.7 0.0 8.1 4 3 4 8 8 8 7 WD40-like domain eIF2A PF08662.11 KIK50337.1 - 1.9e-11 44.2 1.9 0.37 10.6 0.1 5.4 2 2 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK50337.1 - 1.6e-10 39.9 3.7 0.35 9.1 0.0 8.4 1 1 5 10 10 10 5 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK50337.1 - 8.6e-08 32.4 16.4 6.9 7.3 0.0 9.9 11 0 0 11 11 11 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK50337.1 - 2.6e-05 22.9 17.2 0.056 12.0 0.8 5.7 1 1 2 6 6 6 3 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK50337.1 - 0.00016 20.8 18.8 6.8 5.5 0.0 9.5 1 1 10 11 11 11 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK50337.1 - 0.00028 20.7 3.2 5.5 7.1 0.1 7.0 9 0 0 9 9 9 1 PQQ enzyme repeat AHJR-like PF18743.1 KIK50337.1 - 0.025 14.1 0.0 5 6.7 0.0 2.6 2 1 0 2 2 2 0 REase_AHJR-like Kelch_6 PF13964.6 KIK50337.1 - 0.16 12.3 20.2 5.3 7.5 0.2 7.6 8 0 0 8 8 8 0 Kelch motif Coat_X PF07552.11 KIK50337.1 - 6 6.8 8.3 14 5.6 0.0 4.8 6 0 0 6 6 6 0 Spore Coat Protein X and V domain NACHT PF05729.12 KIK50338.1 - 1.1e-08 35.1 0.0 2.2e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK50338.1 - 6e-06 26.7 0.0 1.1e-05 25.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK50338.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK50338.1 - 0.0012 19.2 0.3 0.0067 16.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK50338.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK50338.1 - 0.013 15.9 0.0 0.051 14.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KIK50338.1 - 0.024 14.2 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK50338.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIK50338.1 - 0.058 13.7 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK50338.1 - 0.14 12.7 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AcetylCoA_hyd_C PF13336.6 KIK50339.1 - 4.7e-37 127.3 0.0 7.3e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK50339.1 - 4.5e-23 82.3 0.0 9.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain WD40 PF00400.32 KIK50341.1 - 2.7e-24 85.0 9.4 4.7e-08 33.6 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50341.1 - 2.5e-11 43.7 0.9 0.0014 18.9 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK50341.1 - 9.1e-08 32.2 0.0 7.5e-07 29.2 0.0 2.5 2 1 1 3 3 3 1 NACHT domain AAA_16 PF13191.6 KIK50341.1 - 0.00039 20.9 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK50341.1 - 0.00047 19.4 0.0 0.001 18.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK50341.1 - 0.0041 17.6 0.0 0.15 12.5 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) WD40_like PF17005.5 KIK50341.1 - 0.0043 16.4 2.6 0.047 13.0 0.1 2.9 2 1 1 3 3 3 1 WD40-like domain DUF730 PF05325.11 KIK50341.1 - 0.039 14.0 0.0 3.5 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF730) RNA_helicase PF00910.22 KIK50341.1 - 0.039 14.3 0.0 0.35 11.3 0.0 2.6 3 0 0 3 3 3 0 RNA helicase WD40 PF00400.32 KIK50345.1 - 3.7e-120 388.3 82.2 3.5e-10 40.3 1.4 14.5 15 0 0 15 15 15 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50345.1 - 1.3e-31 108.7 23.0 0.021 15.1 0.1 12.5 1 1 12 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50345.1 - 4.7e-14 52.4 15.3 0.03 13.6 0.3 7.9 2 2 6 8 8 8 6 WD40-like domain Me-amine-dh_H PF06433.11 KIK50345.1 - 6e-09 35.2 0.9 0.4 9.5 0.0 6.1 3 2 2 7 7 7 3 Methylamine dehydrogenase heavy chain (MADH) Frtz PF11768.8 KIK50345.1 - 9.7e-08 30.8 6.4 0.62 8.3 0.1 7.1 4 4 3 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK50345.1 - 6e-06 25.0 9.8 0.11 11.0 0.2 5.1 1 1 2 5 5 5 3 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIK50345.1 - 0.00016 22.1 10.8 1.1 9.9 0.1 8.0 9 0 0 9 9 9 1 PQQ-like domain Ge1_WD40 PF16529.5 KIK50345.1 - 0.00021 20.4 19.8 8.8 5.2 0.0 9.1 1 1 8 11 11 11 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_6 PF13964.6 KIK50345.1 - 0.0045 17.2 14.5 3.7 8.0 0.2 7.0 8 0 0 8 8 8 2 Kelch motif Coat_X PF07552.11 KIK50345.1 - 0.72 9.7 2.1 43 4.0 0.0 3.9 4 0 0 4 4 4 0 Spore Coat Protein X and V domain Methyltr_RsmB-F PF01189.17 KIK50346.1 - 0.11 12.1 1.0 0.25 10.9 0.1 1.9 2 1 0 3 3 3 0 16S rRNA methyltransferase RsmB/F YrbL-PhoP_reg PF10707.9 KIK50347.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Tannase PF07519.11 KIK50348.1 - 2.1e-114 383.0 0.0 2.4e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Mito_carr PF00153.27 KIK50350.1 - 3.4e-53 177.5 9.8 4.9e-20 71.2 2.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Lipase_3 PF01764.25 KIK50351.1 - 1.9e-25 89.4 0.0 2.6e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK50351.1 - 0.0092 16.6 0.1 0.016 15.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KIK50351.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) WD40 PF00400.32 KIK50354.1 - 4.5e-34 115.9 25.3 3.9e-07 30.7 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KIK50354.1 - 2e-12 46.8 2.1 2.6e-12 46.4 0.5 2.1 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KIK50354.1 - 2.7e-11 43.6 0.6 0.0078 16.5 0.0 5.9 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK50354.1 - 1.2e-06 27.5 2.7 0.11 11.2 0.1 4.3 3 1 1 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 KIK50354.1 - 0.0013 18.5 0.1 0.0033 17.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KIK50354.1 - 0.0023 17.3 0.0 6.2 6.1 0.0 4.2 3 1 0 4 4 4 1 WD40-like domain PQQ_3 PF13570.6 KIK50354.1 - 0.059 13.9 8.8 1.8 9.2 0.1 5.2 6 1 1 7 7 7 0 PQQ-like domain DUF5046 PF16465.5 KIK50354.1 - 0.15 11.5 0.1 17 4.7 0.0 3.1 3 1 0 4 4 4 0 Domain of unknown function (DUF5046) DUF1768 PF08719.11 KIK50355.1 - 1.6e-19 70.7 0.0 5.3e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1768) Pkinase_Tyr PF07714.17 KIK50356.1 - 9.1e-43 146.4 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK50356.1 - 3.5e-33 115.1 0.0 5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK50356.1 - 6.6e-05 21.9 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK50356.1 - 0.029 14.3 0.7 0.097 12.6 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK50356.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Peptidase_C14 PF00656.22 KIK50358.1 - 6.8e-18 65.5 0.0 2.7e-17 63.5 0.0 1.7 1 1 1 2 2 2 1 Caspase domain DUF1768 PF08719.11 KIK50360.1 - 3.5e-14 53.4 0.0 5.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF4149 PF13664.6 KIK50361.1 - 5.5 7.4 7.3 0.94 9.8 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) TPR_1 PF00515.28 KIK50363.1 - 4.6e-34 114.9 0.1 4e-08 32.8 0.1 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK50363.1 - 1e-29 100.2 10.5 1.6e-06 27.7 0.1 9.0 10 0 0 10 10 9 6 Tetratricopeptide repeat DnaJ PF00226.31 KIK50363.1 - 2.3e-21 75.7 0.7 4.8e-21 74.6 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 KIK50363.1 - 1.9e-19 70.0 7.3 5.6e-07 30.1 0.1 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIK50363.1 - 4.2e-19 67.9 2.8 8.3e-07 28.6 0.1 7.0 6 2 1 8 8 8 4 TPR repeat TPR_12 PF13424.6 KIK50363.1 - 4.7e-15 55.6 12.3 0.00033 20.9 1.5 6.0 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK50363.1 - 1.1e-13 51.1 3.3 1.9e-05 24.7 0.1 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK50363.1 - 6.1e-13 47.9 7.7 0.0011 19.0 0.1 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK50363.1 - 2.6e-12 47.1 12.0 0.0022 18.5 0.2 5.7 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK50363.1 - 1.3e-10 41.2 8.9 0.58 11.1 0.0 8.1 4 3 5 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK50363.1 - 7.9e-07 29.0 8.4 0.47 10.9 0.0 7.1 8 1 0 8 8 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK50363.1 - 3.2e-06 27.3 6.6 0.041 14.1 0.8 4.6 4 2 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KIK50363.1 - 5.3e-06 26.4 6.7 0.086 12.9 0.2 5.1 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 KIK50363.1 - 1.2e-05 24.9 6.7 0.038 13.4 0.0 4.6 2 1 3 5 5 5 2 MalT-like TPR region DUF3808 PF10300.9 KIK50363.1 - 0.00037 19.4 0.2 0.016 14.0 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_7 PF13176.6 KIK50363.1 - 0.00047 20.0 8.5 0.015 15.3 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK50363.1 - 0.0005 20.5 5.0 1.4 9.8 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK50363.1 - 0.0011 18.8 8.1 3.9 7.5 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 KIK50363.1 - 0.0015 18.2 5.4 5 6.8 0.1 4.6 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 KIK50363.1 - 0.0019 17.6 0.6 7 6.2 0.0 4.1 5 0 0 5 5 5 0 SHNi-TPR Fis1_TPR_C PF14853.6 KIK50363.1 - 0.0045 17.0 6.1 12 6.0 0.0 5.3 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Fmp27 PF10344.9 KIK50363.1 - 0.054 11.6 0.0 0.51 8.4 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial protein from FMP27 TPM_phosphatase PF04536.14 KIK50363.1 - 0.068 13.3 0.3 9.4 6.4 0.1 2.8 2 0 0 2 2 2 0 TPM domain RPN7 PF10602.9 KIK50363.1 - 0.12 12.0 5.4 11 5.7 0.1 4.1 4 1 0 4 4 4 0 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.6 KIK50363.1 - 0.13 12.7 2.3 12 6.3 0.0 3.2 2 2 1 3 3 3 0 Alkyl sulfatase dimerisation Nup88 PF10168.9 KIK50363.1 - 0.18 9.6 3.1 0.28 8.9 3.1 1.2 1 0 0 1 1 1 0 Nuclear pore component Spectrin PF00435.21 KIK50363.1 - 0.18 12.3 1.1 2.1 8.9 0.1 2.9 2 1 1 3 3 3 0 Spectrin repeat DUF3856 PF12968.7 KIK50363.1 - 0.74 9.9 5.9 16 5.5 0.4 3.7 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) ISG65-75 PF11727.8 KIK50363.1 - 1.1 8.4 13.0 0.38 10.0 1.6 2.8 2 1 1 3 3 2 0 Invariant surface glycoprotein BTAD PF03704.17 KIK50363.1 - 1.7 9.0 8.5 19 5.7 3.4 3.8 2 2 0 2 2 2 0 Bacterial transcriptional activator domain DUF4192 PF13830.6 KIK50363.1 - 8.1 6.4 9.9 1.7 8.7 0.2 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) TMCCDC2 PF15844.5 KIK50364.1 - 1 9.2 3.5 12 5.8 0.4 2.2 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Ku_C PF03730.14 KIK50365.1 - 0.097 13.4 0.4 6.3 7.6 0.3 2.6 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF2427 PF10348.9 KIK50367.1 - 0.13 12.1 1.9 0.14 11.9 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) ANAPC4_WD40 PF12894.7 KIK50371.1 - 1.4e-10 41.3 0.0 0.19 12.1 0.0 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK50371.1 - 6.4e-09 36.3 8.6 0.00018 22.2 0.0 5.1 3 2 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK50371.1 - 2.7e-06 26.6 0.5 1.3 7.9 0.0 5.0 1 1 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK50371.1 - 5e-05 22.8 1.1 8.7 5.6 0.0 5.0 1 1 5 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK50371.1 - 0.00012 20.6 0.0 0.006 15.0 0.0 2.0 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK50371.1 - 0.0051 16.7 1.1 11 6.0 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat MinC_C PF03775.16 KIK50371.1 - 0.047 13.7 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain eIF2A PF08662.11 KIK50371.1 - 0.14 12.0 0.0 3.3 7.6 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A OPT PF03169.15 KIK50374.1 - 7.4e-08 31.5 0.7 8.8e-08 31.2 0.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF11 PF01345.18 KIK50375.1 - 0.35 11.2 0.0 0.35 11.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF11 Phage_Mu_Gam PF07352.12 KIK50377.1 - 0.21 11.5 2.6 0.76 9.7 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DOT1 PF08123.13 KIK50378.1 - 6.8e-44 149.8 0.0 7.7e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 KIK50378.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KIK50378.1 - 0.21 11.4 1.4 0.79 9.5 1.4 1.8 1 1 0 1 1 1 0 Methyltransferase domain PfaD_N PF18328.1 KIK50379.1 - 0.16 11.9 0.0 0.64 10.0 0.0 1.9 2 0 0 2 2 2 0 Fatty acid synthase subunit PfaD N-terminal domain RVP_2 PF08284.11 KIK50380.1 - 0.00022 21.0 0.1 0.00031 20.5 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK50380.1 - 0.0008 20.0 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK50380.1 - 0.0037 17.8 0.0 0.0093 16.5 0.0 1.7 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Plavaka PF18759.1 KIK50382.1 - 2.2e-14 53.4 0.2 5.1e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK50383.1 - 1.4e-57 195.3 0.0 1.7e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK50384.1 - 2.8e-16 59.7 0.1 1.4e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 Plavaka transposase OTT_1508_deam PF14441.6 KIK50385.1 - 1.4e-07 31.4 0.1 4e-07 29.9 0.1 1.9 1 0 0 1 1 1 1 OTT_1508-like deaminase TRAPP PF04051.16 KIK50386.1 - 1.7e-15 57.0 0.0 2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CW_7 PF08230.11 KIK50387.1 - 0.18 11.6 0.9 0.33 10.7 0.9 1.3 1 0 0 1 1 1 0 CW_7 repeat Dor1 PF04124.12 KIK50391.1 - 3.5e-42 144.3 0.2 7.8e-42 143.2 0.2 1.5 1 1 0 1 1 1 1 Dor1-like family PIP5K PF01504.18 KIK50391.1 - 1.4e-18 67.1 0.0 2.5e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sec5 PF15469.6 KIK50391.1 - 0.021 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 Y_phosphatase PF00102.27 KIK50392.1 - 8e-16 58.3 0.1 1.3e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FtsK_SpoIIIE PF01580.18 KIK50393.1 - 0.0032 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family RHSP PF07999.11 KIK50393.1 - 0.0041 16.0 0.0 0.0096 14.8 0.0 1.6 1 1 0 1 1 1 1 Retrotransposon hot spot protein AAA_16 PF13191.6 KIK50393.1 - 0.021 15.2 0.0 0.036 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 KIK50393.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 KIK50393.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK50393.1 - 0.16 11.8 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-MYND PF01753.18 KIK50394.1 - 5.4e-06 26.4 17.9 1.7e-05 24.8 17.9 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIK50394.1 - 3.8 7.9 17.0 7.3 7.0 17.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DHC_N1 PF08385.12 KIK50397.1 - 7.1e-71 239.5 6.9 1e-36 126.8 2.3 3.4 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 Unstab_antitox PF09720.10 KIK50397.1 - 0.13 12.3 0.3 1.7 8.8 0.1 2.9 2 0 0 2 2 2 0 Putative addiction module component SDA1 PF05285.12 KIK50398.1 - 0.87 9.0 38.2 1.8 7.9 38.2 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK50398.1 - 1.7 6.8 35.8 2.7 6.1 35.8 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KIK50398.1 - 9.5 5.4 40.5 0.49 9.7 35.3 1.5 2 0 0 2 2 2 0 BUD22 Asp_protease_2 PF13650.6 KIK50401.1 - 4.8e-06 27.1 0.0 1.1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK50401.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK50401.1 - 0.057 13.2 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 KIK50401.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CitX PF03802.14 KIK50402.1 - 0.18 11.5 0.3 1 9.1 0.2 1.9 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Retrotrans_gag PF03732.17 KIK50403.1 - 2.3e-07 31.0 0.0 5.9e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK50403.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) HALZ PF02183.18 KIK50404.1 - 0.00073 19.7 3.8 0.38 11.0 0.7 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper bZIP_1 PF00170.21 KIK50404.1 - 0.012 15.7 3.6 0.33 11.1 0.4 2.1 1 1 1 2 2 2 0 bZIP transcription factor Raptor_N PF14538.6 KIK50404.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain bZIP_2 PF07716.15 KIK50404.1 - 0.3 11.2 4.5 7.9 6.7 1.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper JIP_LZII PF16471.5 KIK50404.1 - 0.36 11.0 4.7 0.5 10.6 4.7 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II MaoC_dehydrat_N PF13452.6 KIK50405.1 - 3.4e-08 33.7 0.0 7.8e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Acyl_transf_1 PF00698.21 KIK50406.1 - 1.6e-14 54.1 0.0 3.1e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Acyl transferase domain SlpA PF03217.14 KIK50406.1 - 0.14 12.7 0.4 0.91 10.2 0.1 2.2 2 0 0 2 2 2 0 Surface later protein A domain Plavaka PF18759.1 KIK50407.1 - 1.9e-05 24.1 0.0 2.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK50408.1 - 1.2e-55 189.0 0.1 1.3e-55 188.9 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase DUF1360 PF07098.11 KIK50412.1 - 0.019 14.9 1.9 0.031 14.2 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) SYF2 PF08231.12 KIK50415.1 - 0.034 14.5 0.1 0.04 14.3 0.1 1.1 1 0 0 1 1 1 0 SYF2 splicing factor zf-CCHC PF00098.23 KIK50416.1 - 1.9e-07 30.9 6.3 2.8e-07 30.3 6.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KIK50416.1 - 0.0019 18.1 2.1 0.0024 17.8 2.1 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIK50416.1 - 0.0066 16.1 3.3 0.0091 15.7 3.3 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KIK50416.1 - 0.0093 15.8 4.3 0.014 15.2 4.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KIK50417.1 - 0.00015 21.9 0.4 0.00022 21.4 0.4 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Dehydratase_hem PF13816.6 KIK50417.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase MFS_1 PF07690.16 KIK50419.1 - 4.4e-05 22.6 2.4 5.8e-05 22.2 2.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK50419.1 - 0.003 16.5 2.2 0.0059 15.5 2.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK50420.1 - 4.4e-07 29.1 4.7 4.5e-07 29.1 4.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 KIK50422.1 - 8.1e-13 48.7 0.0 9.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK50422.1 - 9.8e-11 41.2 0.4 5.5e-10 38.7 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family PGAP1 PF07819.13 KIK50422.1 - 0.0091 15.7 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.7 KIK50422.1 - 0.014 16.0 0.1 0.028 15.0 0.1 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KIK50422.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase zf-CCHC PF00098.23 KIK50427.1 - 0.00059 19.8 3.1 0.0012 18.8 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Hydrolase_3 PF08282.12 KIK50432.1 - 0.021 14.6 4.3 0.027 14.2 4.3 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pinin_SDK_memA PF04696.13 KIK50432.1 - 0.91 9.6 12.8 0.62 10.1 10.7 1.7 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Bromo_TP_like PF17027.5 KIK50433.1 - 0.04 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Histone-fold protein SesA PF17107.5 KIK50433.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases UPF0242 PF06785.11 KIK50434.1 - 0.0021 18.2 2.9 0.0021 18.2 2.9 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KIK50434.1 - 0.028 13.8 8.8 0.033 13.5 8.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 KIK50434.1 - 0.031 15.0 6.4 0.031 15.0 5.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 KIK50434.1 - 0.036 14.1 7.5 1 9.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GCN5L1 PF06320.13 KIK50434.1 - 0.13 12.4 5.2 0.17 12.1 5.2 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DivIC PF04977.15 KIK50434.1 - 0.21 11.4 4.2 0.11 12.3 1.1 1.8 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 KIK50434.1 - 0.25 11.3 12.5 0.13 12.3 5.7 2.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KIK50434.1 - 0.82 10.3 4.4 2.1 9.0 3.9 1.9 1 1 1 2 2 2 0 SlyX YabA PF06156.13 KIK50434.1 - 1.2 9.8 5.4 0.72 10.5 3.3 1.7 1 1 1 2 2 2 0 Initiation control protein YabA LPP PF04728.13 KIK50434.1 - 3.9 7.9 6.7 13 6.2 1.0 2.7 1 1 1 2 2 2 0 Lipoprotein leucine-zipper GMC_oxred_N PF00732.19 KIK50435.1 - 1.6e-41 142.6 0.0 2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK50435.1 - 5.4e-09 36.7 0.0 1.9e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase AMP-binding PF00501.28 KIK50436.1 - 9.7e-19 67.2 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TMEM192 PF14802.6 KIK50437.1 - 0.13 11.4 2.6 0.25 10.4 2.4 1.6 1 1 0 1 1 1 0 TMEM192 family Ferlin_C PF16165.5 KIK50437.1 - 3.4 7.6 6.8 11 5.9 0.4 2.3 2 0 0 2 2 2 0 Ferlin C-terminus MFS_1 PF07690.16 KIK50439.1 - 1.8e-38 132.4 30.0 1.8e-38 132.4 30.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK50439.1 - 0.00061 18.3 3.0 0.001 17.6 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF21 PF01595.20 KIK50439.1 - 1.7 8.3 10.2 6.4 6.5 1.0 4.0 3 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain DUF2200 PF09966.9 KIK50440.1 - 0.025 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) HD_2 PF12917.7 KIK50440.1 - 0.036 13.8 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Helicase_C PF00271.31 KIK50442.1 - 7.4e-09 35.9 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 KIK50442.1 - 0.0021 18.2 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KIK50444.1 - 6.2e-13 48.9 0.0 7.8e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK50444.1 - 1.4e-09 38.2 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIK50444.1 - 0.057 12.9 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 KIK50444.1 - 0.098 12.6 0.2 0.32 11.0 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain NACHT PF05729.12 KIK50445.1 - 1e-05 25.5 0.1 3.9e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK50445.1 - 0.00096 18.4 0.5 0.0028 16.9 0.1 2.0 2 1 1 3 3 3 1 NB-ARC domain APS_kinase PF01583.20 KIK50445.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 KIK50445.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KIK50445.1 - 0.02 15.3 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KIK50445.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 KIK50445.1 - 0.11 11.7 0.3 0.17 11.1 0.3 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 KIK50445.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK50445.1 - 0.15 12.1 0.0 0.76 9.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain BRK PF07533.16 KIK50445.1 - 0.16 11.6 0.3 56 3.5 0.0 3.1 3 0 0 3 3 3 0 BRK domain NACHT PF05729.12 KIK50446.1 - 3.5e-07 30.3 0.0 9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK50446.1 - 8e-05 21.9 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK50446.1 - 0.0069 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KIK50446.1 - 0.011 15.7 0.0 0.33 11.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK50446.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KIK50446.1 - 0.017 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK50446.1 - 0.025 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK50446.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK50446.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Abhydrolase_6 PF12697.7 KIK50448.1 - 2e-10 41.7 0.0 3.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK50448.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK50448.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK50448.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 KIK50448.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 KIK50448.1 - 0.061 11.8 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II adh_short PF00106.25 KIK50450.1 - 1.5e-23 83.3 0.4 5.9e-23 81.3 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK50450.1 - 1.8e-15 57.2 0.1 7.1e-15 55.2 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK50450.1 - 5.4e-09 36.2 0.1 8e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK50450.1 - 0.00068 18.9 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KIK50450.1 - 0.0015 18.8 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIK50450.1 - 0.0025 18.4 0.1 0.0079 16.8 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIK50450.1 - 0.029 13.9 0.1 0.054 13.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIK50450.1 - 0.036 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KIK50450.1 - 0.067 13.8 0.1 0.36 11.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK50450.1 - 0.15 12.5 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Ribonuclease_3 PF00636.26 KIK50451.1 - 4.2e-22 78.7 0.0 7e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KIK50451.1 - 2.1e-19 69.4 0.0 5.2e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KIK50451.1 - 2.4e-15 56.8 0.0 6.4e-08 32.8 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 KIK50451.1 - 1.1e-12 48.3 0.0 2.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK50451.1 - 2.5e-07 30.6 0.0 6.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK50451.1 - 2.2e-06 27.8 0.0 0.00027 21.0 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit p450 PF00067.22 KIK50452.1 - 1.7e-60 205.1 0.0 2.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIK50453.1 - 0.046 13.6 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like WD40 PF00400.32 KIK50454.1 - 8e-23 80.3 15.6 0.0012 19.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat SIR2 PF02146.17 KIK50455.1 - 6.3e-27 94.6 0.0 9.2e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family adh_short_C2 PF13561.6 KIK50455.1 - 0.02 14.4 0.0 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF4451 PF14616.6 KIK50457.1 - 2.6e-05 24.4 3.4 0.25 11.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4451) zf_UBZ PF18439.1 KIK50457.1 - 0.42 10.2 5.2 20 4.9 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger BIR PF00653.21 KIK50457.1 - 4.5 8.0 11.2 17 6.1 0.4 3.3 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Glyco_hydro_16 PF00722.21 KIK50458.1 - 1.3e-05 24.8 0.4 2.4e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PAP2 PF01569.21 KIK50459.1 - 2e-13 50.3 3.3 3e-13 49.7 3.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily Polysacc_synt_C PF14667.6 KIK50459.1 - 0.028 14.5 0.5 0.041 13.9 0.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PGM_PMM_I PF02878.16 KIK50460.1 - 9.9e-36 122.5 0.2 1.5e-35 121.9 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIK50460.1 - 2.8e-26 91.9 0.0 7.2e-26 90.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIK50460.1 - 1.5e-13 51.3 0.0 5.1e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIK50460.1 - 6.2e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2460 PF09343.10 KIK50460.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) Carb_kinase PF01256.17 KIK50461.1 - 1.2e-51 175.5 0.0 1.8e-49 168.4 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KIK50461.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase NfI_DNAbd_pre-N PF10524.9 KIK50462.1 - 0.013 15.4 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus BTB PF00651.31 KIK50463.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF2729 PF10870.8 KIK50464.1 - 0.033 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) MitMem_reg PF13012.6 KIK50465.1 - 1.7e-35 121.8 1.3 3e-35 121.0 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIK50465.1 - 9.1e-30 103.1 0.0 1.6e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Fibrillarin PF01269.17 KIK50466.1 - 9.1e-104 345.5 0.0 1.1e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KIK50466.1 - 0.0018 18.0 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KIK50466.1 - 0.011 15.6 0.1 0.017 14.9 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2423 PF10338.9 KIK50466.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) FtsJ PF01728.19 KIK50466.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase tRNA-synt_1d PF00750.19 KIK50467.1 - 2.9e-98 329.0 4.6 2.9e-98 329.0 4.6 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KIK50467.1 - 8.7e-20 71.1 0.0 1.8e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2250 PF10007.9 KIK50467.1 - 0.0087 16.1 0.3 0.031 14.4 0.3 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) RecX PF02631.16 KIK50467.1 - 0.032 14.7 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 RecX family zf-C2H2 PF00096.26 KIK50468.1 - 8.8e-08 32.2 11.0 0.0035 17.7 1.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIK50468.1 - 1.1e-07 31.5 9.5 0.00041 20.0 0.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK50468.1 - 1.9e-06 28.0 13.0 0.012 16.0 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK50468.1 - 6.6e-06 26.5 9.7 0.064 14.1 1.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KIK50468.1 - 0.034 14.5 0.7 0.17 12.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KIK50468.1 - 0.048 13.3 0.1 0.62 9.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 KIK50468.1 - 0.25 12.0 7.3 5.4 7.7 0.3 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain GAGA PF09237.11 KIK50468.1 - 0.36 10.7 4.1 0.17 11.7 0.5 2.1 2 0 0 2 2 2 0 GAGA factor zf-BED PF02892.15 KIK50468.1 - 0.52 10.4 2.8 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 BED zinc finger DUF2631 PF10939.8 KIK50469.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Acetyltransf_1 PF00583.25 KIK50470.1 - 2e-05 24.8 0.0 3.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK50470.1 - 7.6e-05 22.7 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK50470.1 - 0.00053 20.1 0.1 0.0085 16.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK50470.1 - 0.0006 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK50470.1 - 0.041 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 KIK50470.1 - 0.11 12.7 0.2 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mid2 PF04478.12 KIK50471.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rick_17kDa_Anti PF05433.15 KIK50471.1 - 0.031 14.2 0.3 0.074 12.9 0.3 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain SEF14_adhesin PF06443.11 KIK50471.1 - 0.1 12.4 3.8 0.9 9.4 0.3 2.9 3 0 0 3 3 3 0 SEF14-like adhesin PKD PF00801.20 KIK50471.1 - 0.35 10.8 4.3 11 6.0 0.2 4.1 4 1 0 4 4 4 0 PKD domain p450 PF00067.22 KIK50472.1 - 1.1e-54 186.0 0.0 1.4e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM220 PF15487.6 KIK50473.1 - 0.033 13.8 2.5 0.054 13.1 2.5 1.3 1 0 0 1 1 1 0 FAM220 family Pantoate_ligase PF02569.15 KIK50474.1 - 2.2e-91 305.7 0.0 2.5e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CENP-C_C PF11699.8 KIK50475.1 - 1.5e-26 92.4 0.1 2.8e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIK50475.1 - 5.2e-07 29.3 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 KIK50475.1 - 0.0014 18.5 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase p450 PF00067.22 KIK50476.1 - 6.3e-57 193.3 0.0 7.8e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK50479.1 - 2.7e-226 724.2 50.7 1.6e-10 41.4 0.0 21.9 22 0 0 22 22 22 21 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50479.1 - 2.1e-60 201.0 18.0 0.018 15.3 0.0 19.9 1 1 19 20 20 20 17 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50479.1 - 3.1e-36 125.1 9.7 6.3e-05 22.9 0.2 9.8 1 1 9 12 12 12 10 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50479.1 - 1.5e-26 93.2 27.9 1.8 7.1 0.1 18.6 7 5 9 20 20 20 13 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50479.1 - 1.1e-21 77.4 11.7 6.2 6.1 0.0 16.8 17 2 2 19 19 19 4 WD40-like domain PD40 PF07676.12 KIK50479.1 - 4.8e-21 74.2 0.0 21 5.2 0.0 17.1 19 0 0 19 19 19 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK50479.1 - 1.5e-20 72.9 38.3 3.8 7.5 0.0 19.3 20 0 0 20 20 20 1 Nitrous oxide reductase propeller repeat Ge1_WD40 PF16529.5 KIK50479.1 - 8.1e-13 48.0 16.1 9.6 5.1 0.0 15.9 3 2 16 19 19 19 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NHL PF01436.21 KIK50479.1 - 1.6e-10 40.5 20.1 58 4.0 0.0 16.3 18 0 0 18 18 18 0 NHL repeat Str_synth PF03088.16 KIK50479.1 - 1.4e-07 31.6 0.2 20 5.4 0.0 9.3 5 2 9 14 14 14 0 Strictosidine synthase Imm17 PF15562.6 KIK50479.1 - 2.6e-07 30.4 0.0 26 4.7 0.0 9.2 14 0 0 14 14 13 0 Immunity protein 17 Peptidase_S9_N PF02897.15 KIK50479.1 - 2.9e-07 29.6 12.0 12 4.6 0.0 10.7 4 3 5 11 11 11 0 Prolyl oligopeptidase, N-terminal beta-propeller domain COPI_C PF06957.11 KIK50479.1 - 1.6e-06 27.2 0.0 39 2.8 0.0 9.5 4 4 11 16 16 16 0 Coatomer (COPI) alpha subunit C-terminus DsbC_N PF10411.9 KIK50479.1 - 3.1e-05 23.3 18.5 2.4e+02 1.3 0.0 14.5 18 0 0 18 18 18 0 Disulfide bond isomerase protein N-terminus Cuticle_4 PF15955.5 KIK50479.1 - 9.5e-05 23.0 8.2 3.9e+02 1.8 0.0 12.0 18 0 0 18 18 14 0 Cuticle protein LRR_10 PF18805.1 KIK50479.1 - 0.00041 19.9 52.2 2.5 7.8 0.1 17.1 15 5 5 20 20 20 2 Leucine-rich repeat DUF2635 PF10948.8 KIK50479.1 - 0.098 12.4 0.1 41 4.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2635) AsnC_trans_reg PF01037.21 KIK50479.1 - 5.1 7.1 7.7 3.7e+02 1.2 0.0 7.2 13 0 0 13 13 10 0 Lrp/AsnC ligand binding domain ATP-synt_G PF04718.15 KIK50480.1 - 2e-05 25.3 3.9 0.0043 17.8 0.6 3.0 2 1 1 3 3 3 2 Mitochondrial ATP synthase g subunit HisKA_3 PF07730.13 KIK50480.1 - 0.17 12.4 0.0 3 8.4 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase WD40 PF00400.32 KIK50481.1 - 2e-128 414.5 43.1 1.1e-11 45.1 0.1 12.4 13 0 0 13 13 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50481.1 - 1.3e-36 124.7 8.2 0.017 15.4 0.0 11.9 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50481.1 - 3.3e-24 85.9 0.2 9.8e-05 22.3 0.0 6.1 1 1 6 7 7 7 7 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK50481.1 - 1.7e-15 56.5 0.4 41 4.3 0.0 12.0 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK50481.1 - 1.6e-14 53.5 15.4 0.98 8.0 0.0 10.5 4 2 5 11 11 11 6 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50481.1 - 3.1e-13 49.7 5.1 6.8 5.9 0.0 10.2 10 2 0 10 10 10 3 WD40-like domain Ge1_WD40 PF16529.5 KIK50481.1 - 1.3e-11 44.1 7.1 5 6.0 0.0 10.7 1 1 10 12 12 12 3 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK50481.1 - 5.8e-11 42.1 16.8 8.5 6.4 0.0 10.6 11 0 0 11 11 11 2 Nitrous oxide reductase propeller repeat COPI_C PF06957.11 KIK50481.1 - 6.5e-07 28.4 0.0 1.4 7.6 0.0 7.2 2 2 7 9 9 9 1 Coatomer (COPI) alpha subunit C-terminus NHL PF01436.21 KIK50481.1 - 7.1e-07 29.0 18.1 19 5.5 0.1 10.5 11 0 0 11 11 11 0 NHL repeat DsbC_N PF10411.9 KIK50481.1 - 1.7e-06 27.3 12.9 70 3.0 0.0 10.8 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus SdiA-regulated PF06977.11 KIK50481.1 - 1.7e-05 24.2 0.0 0.37 10.0 0.0 4.6 3 1 2 5 5 5 1 SdiA-regulated LRR_10 PF18805.1 KIK50481.1 - 0.00028 20.5 23.0 39 4.0 0.0 9.9 6 4 3 10 10 10 0 Leucine-rich repeat Peptidase_S9_N PF02897.15 KIK50481.1 - 0.0003 19.7 3.2 5.6 5.7 0.0 6.1 1 1 4 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Imm17 PF15562.6 KIK50481.1 - 0.0065 16.3 0.0 21 5.1 0.0 6.1 9 0 0 9 9 9 0 Immunity protein 17 Cuticle_4 PF15955.5 KIK50481.1 - 0.01 16.5 2.0 1.2e+02 3.5 0.0 6.3 7 1 0 8 8 8 0 Cuticle protein AsnC_trans_reg PF01037.21 KIK50481.1 - 0.011 15.7 7.0 1.3e+02 2.7 0.0 7.6 11 0 0 11 11 10 0 Lrp/AsnC ligand binding domain TFIIIC_delta PF12657.7 KIK50481.1 - 0.52 10.2 7.0 9.5e+02 -0.4 7.0 5.3 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KIK50484.1 - 1.4e-48 161.8 9.2 3e-10 40.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50484.1 - 8.4e-15 54.9 0.3 0.041 14.2 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK50484.1 - 6.7e-08 31.6 1.5 1 8.0 0.0 4.0 2 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK50484.1 - 7.3e-08 32.5 0.0 0.0023 17.9 0.0 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A nos_propeller PF18764.1 KIK50484.1 - 1.4e-06 28.1 2.4 4.8 7.2 0.0 5.0 4 1 1 5 5 5 1 Nitrous oxide reductase propeller repeat Ge1_WD40 PF16529.5 KIK50484.1 - 8.3e-06 25.0 0.3 3.5 6.5 0.0 4.2 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SecA_PP_bind PF01043.20 KIK50484.1 - 1e-05 26.2 0.8 5.3 7.7 0.0 4.8 3 1 1 5 5 5 1 SecA preprotein cross-linking domain WD40_like PF17005.5 KIK50484.1 - 2.9e-05 23.6 0.2 3.8 6.7 0.0 4.2 4 1 1 5 5 5 2 WD40-like domain PD40 PF07676.12 KIK50484.1 - 0.00043 20.1 0.1 30 4.7 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Phi29_Phage_SSB PF17427.2 KIK50484.1 - 0.00058 20.0 0.1 35 4.6 0.0 4.9 4 1 1 5 5 5 0 Phage Single-stranded DNA-binding protein LRR_10 PF18805.1 KIK50484.1 - 0.00079 19.0 4.7 7.1 6.4 0.0 5.0 5 0 0 5 5 5 1 Leucine-rich repeat Proteasome_A_N PF10584.9 KIK50484.1 - 0.0073 16.0 0.5 7.2 6.4 0.0 4.6 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Pectate_lyase_3 PF12708.7 KIK50484.1 - 0.08 12.8 6.3 1.8 8.3 0.1 3.4 1 1 3 4 4 4 0 Pectate lyase superfamily protein DsbC_N PF10411.9 KIK50484.1 - 0.089 12.3 0.5 46 3.6 0.0 3.8 5 0 0 5 5 5 0 Disulfide bond isomerase protein N-terminus NHL PF01436.21 KIK50484.1 - 0.095 12.8 3.4 1.1e+02 3.1 0.0 4.4 5 0 0 5 5 5 0 NHL repeat WD40 PF00400.32 KIK50487.1 - 9e-151 485.2 35.8 2e-10 41.1 0.1 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50487.1 - 2.7e-47 159.0 12.7 0.053 13.8 0.0 14.3 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50487.1 - 1.8e-30 106.3 3.1 2.7e-05 24.2 0.0 6.4 1 1 3 6 6 6 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50487.1 - 1.4e-17 63.6 17.8 0.43 9.2 0.2 12.2 5 3 7 13 13 13 8 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50487.1 - 4e-17 62.5 14.8 8 5.7 0.0 13.4 13 1 0 13 13 13 2 WD40-like domain PD40 PF07676.12 KIK50487.1 - 4.3e-14 52.0 0.0 56 3.8 0.0 12.6 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat potato_inhibit PF00280.18 KIK50487.1 - 1.3e-09 38.5 14.5 9.9 6.9 0.0 12.4 8 4 6 14 14 14 1 Potato inhibitor I family SdiA-regulated PF06977.11 KIK50487.1 - 6.5e-09 35.4 0.0 0.56 9.4 0.0 6.0 1 1 6 8 8 8 3 SdiA-regulated nos_propeller PF18764.1 KIK50487.1 - 1.4e-06 28.1 27.4 18 5.3 0.0 12.6 14 0 0 14 14 14 0 Nitrous oxide reductase propeller repeat NHL PF01436.21 KIK50487.1 - 1.4e-05 24.9 27.3 20 5.4 0.0 12.8 14 0 0 14 14 14 0 NHL repeat Str_synth PF03088.16 KIK50487.1 - 2.5e-05 24.3 0.3 55 4.0 0.0 7.7 6 3 5 11 11 11 0 Strictosidine synthase DsbC_N PF10411.9 KIK50487.1 - 3.8e-05 23.1 22.1 61 3.2 0.0 13.2 15 0 0 15 15 15 0 Disulfide bond isomerase protein N-terminus COPI_C PF06957.11 KIK50487.1 - 0.00023 20.1 0.0 20 3.8 0.0 7.0 1 1 8 10 10 10 0 Coatomer (COPI) alpha subunit C-terminus Imm17 PF15562.6 KIK50487.1 - 0.023 14.6 0.0 2.9e+02 1.4 0.0 6.5 8 0 0 8 8 8 0 Immunity protein 17 LRR_10 PF18805.1 KIK50487.1 - 0.032 13.9 25.8 73 3.1 0.1 11.5 10 3 3 13 13 13 0 Leucine-rich repeat TFIIIC_delta PF12657.7 KIK50487.1 - 0.24 11.3 8.5 2.5e+03 -1.8 8.4 5.5 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Cuticle_4 PF15955.5 KIK50487.1 - 0.47 11.2 2.1 1.8e+02 2.9 0.0 5.4 7 0 0 7 7 5 0 Cuticle protein PQQ_3 PF13570.6 KIK50487.1 - 1.2 9.7 46.1 1.1 9.9 0.1 11.1 2 2 10 12 12 12 0 PQQ-like domain WD40 PF00400.32 KIK50489.1 - 1.2e-137 443.7 41.2 1.6e-10 41.4 0.0 12.9 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50489.1 - 3.6e-45 152.2 10.3 0.0059 16.9 0.0 12.0 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50489.1 - 1.6e-24 86.9 5.0 3.4e-05 23.8 0.0 5.4 1 1 4 6 6 6 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50489.1 - 2.4e-23 82.6 15.5 0.024 13.3 0.1 11.8 8 2 3 12 12 12 8 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50489.1 - 5.5e-18 65.3 6.2 0.19 11.0 0.0 10.8 10 1 1 11 11 11 3 WD40-like domain PD40 PF07676.12 KIK50489.1 - 3.6e-16 58.6 0.0 29 4.8 0.0 12.1 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50489.1 - 1.1e-15 57.4 5.2 3.5 6.5 0.0 11.4 1 1 11 12 12 12 1 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK50489.1 - 1.7e-15 56.6 17.4 6.1 6.8 0.0 11.7 12 0 0 12 12 12 1 Nitrous oxide reductase propeller repeat potato_inhibit PF00280.18 KIK50489.1 - 9.8e-11 42.2 15.3 9 7.1 0.0 10.8 7 2 4 11 11 11 0 Potato inhibitor I family COPI_C PF06957.11 KIK50489.1 - 1.1e-07 31.0 0.0 11 4.7 0.0 8.6 1 1 8 11 11 11 0 Coatomer (COPI) alpha subunit C-terminus DsbC_N PF10411.9 KIK50489.1 - 1.5e-07 30.8 17.0 68 3.0 0.0 11.6 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus Imm17 PF15562.6 KIK50489.1 - 3.3e-06 26.9 0.0 40 4.2 0.0 8.4 11 0 0 11 11 11 0 Immunity protein 17 Pectate_lyase_3 PF12708.7 KIK50489.1 - 3.5e-06 27.0 31.7 2.3 8.0 0.1 9.5 1 1 9 11 11 11 5 Pectate lyase superfamily protein Proteasome_A_N PF10584.9 KIK50489.1 - 5.3e-06 26.0 9.7 1e+02 2.7 0.0 11.2 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature DUF5122 PF17164.4 KIK50489.1 - 1.1e-05 25.6 17.1 91 3.5 0.0 10.5 12 0 0 12 12 10 0 Domain of unknown function (DUF5122) beta-propeller SdiA-regulated PF06977.11 KIK50489.1 - 0.00014 21.2 0.0 2.2 7.4 0.0 4.9 3 2 1 5 5 5 1 SdiA-regulated LRR_10 PF18805.1 KIK50489.1 - 0.00031 20.3 35.0 18 5.1 0.3 11.3 6 3 6 12 12 12 0 Leucine-rich repeat NHL PF01436.21 KIK50489.1 - 0.00036 20.4 22.4 1.1e+02 3.1 0.0 11.2 12 0 0 12 12 12 0 NHL repeat PQQ_2 PF13360.6 KIK50489.1 - 0.015 14.9 33.9 1.3 8.6 5.4 4.7 1 1 0 2 2 2 0 PQQ-like domain Frtz PF11768.8 KIK50489.1 - 0.025 12.9 0.0 69 1.6 0.0 5.3 1 1 3 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyco_hydro_38C PF07748.13 KIK50489.1 - 0.084 12.9 0.1 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain AsnC_trans_reg PF01037.21 KIK50489.1 - 0.13 12.2 2.0 3.7e+02 1.2 0.0 6.4 12 0 0 12 12 9 0 Lrp/AsnC ligand binding domain PQQ_3 PF13570.6 KIK50489.1 - 2.9 8.5 50.8 3.8 8.1 0.4 10.5 2 2 10 12 12 12 0 PQQ-like domain Colicin_E5 PF12106.8 KIK50489.1 - 3.8 7.9 35.2 49 4.3 0.0 10.9 10 2 2 12 12 12 0 Colicin E5 ribonuclease domain DUF2314 PF10077.9 KIK50489.1 - 4.2 7.5 6.1 1.4 9.0 0.3 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2314) MRP-L20 PF12824.7 KIK50491.1 - 0.13 12.4 1.5 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 WD40 PF00400.32 KIK50492.1 - 7.2e-50 165.9 27.6 5.4e-09 36.5 0.3 8.2 7 2 2 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50492.1 - 4.1e-19 68.7 0.3 0.029 14.7 0.0 6.9 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50492.1 - 5.6e-10 38.9 8.4 0.54 10.3 0.0 7.2 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK50492.1 - 9.5e-08 32.1 3.7 0.0045 16.8 0.2 4.1 1 1 4 5 5 5 2 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 KIK50492.1 - 4.2e-07 29.2 0.7 0.6 9.0 0.0 5.4 5 1 1 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4072 PF13284.6 KIK50492.1 - 0.00062 20.2 0.0 7.4 7.1 0.0 3.7 4 0 0 4 4 3 1 Domain of unknown function (DUF4072) Cuticle_4 PF15955.5 KIK50492.1 - 0.014 16.1 0.2 28 5.5 0.0 4.4 5 0 0 5 5 5 0 Cuticle protein WD40_like PF17005.5 KIK50492.1 - 0.014 14.8 0.0 1.1 8.5 0.1 3.7 4 2 1 5 5 5 0 WD40-like domain tRNA_deacylase PF04414.12 KIK50492.1 - 0.035 13.6 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 D-aminoacyl-tRNA deacylase DUF5018 PF16410.5 KIK50492.1 - 0.093 11.4 0.1 3.5 6.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5018) PQQ_3 PF13570.6 KIK50492.1 - 1.9 9.1 8.0 9.5 6.9 0.0 5.1 5 1 1 6 6 6 0 PQQ-like domain Proteasome_A_N PF10584.9 KIK50492.1 - 4.4 7.1 17.9 47 3.8 0.0 6.9 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature RPW8 PF05659.11 KIK50496.1 - 0.049 13.3 1.2 0.1 12.3 1.1 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PKcGMP_CC PF16808.5 KIK50496.1 - 0.23 11.4 6.5 7.5 6.5 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK50496.1 - 0.78 9.8 3.4 0.31 11.1 0.2 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Csm1_N PF18504.1 KIK50496.1 - 0.78 10.1 8.2 6.1 7.3 1.0 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain HMMR_N PF15905.5 KIK50496.1 - 1 8.8 12.7 1.6 8.1 12.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Helitron_like_N PF14214.6 KIK50500.1 - 8.9e-20 71.7 0.0 1.1e-19 71.4 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Peptidase_M10 PF00413.24 KIK50501.1 - 0.023 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Matrixin COX6B PF02297.17 KIK50502.1 - 2 8.7 6.3 22 5.3 0.1 3.2 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIb GTF2I PF02946.14 KIK50507.1 - 0.0011 18.9 0.0 0.0024 17.9 0.0 1.6 2 0 0 2 2 2 1 GTF2I-like repeat SNCAIP_SNCA_bd PF16700.5 KIK50512.1 - 0.005 16.5 0.0 6.9 6.5 0.0 2.9 2 0 0 2 2 2 2 Synphilin-1 alpha-Synuclein-binding domain Presenilin PF01080.17 KIK50516.1 - 0.082 11.7 4.3 0.096 11.4 4.3 1.0 1 0 0 1 1 1 0 Presenilin DUF4637 PF15470.6 KIK50516.1 - 2 8.1 6.6 2.6 7.7 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Homeodomain PF00046.29 KIK50519.1 - 0.0075 16.1 0.7 0.02 14.7 0.2 2.0 2 0 0 2 2 2 1 Homeodomain DUF4510 PF14971.6 KIK50519.1 - 0.034 14.5 0.3 0.049 14.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) TetR_C_8 PF14278.6 KIK50521.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region tRNA-synt_2b PF00587.25 KIK50524.1 - 8.8e-07 29.1 0.0 0.03 14.3 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HC2 PF07382.11 KIK50527.1 - 0.0011 19.1 6.8 0.0011 19.1 6.8 2.3 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 GCOM2 PF15328.6 KIK50527.1 - 3.9 7.8 7.6 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 EBP PF05241.12 KIK50528.1 - 0.11 11.9 14.7 0.3 10.5 14.7 1.8 1 1 0 1 1 1 0 Emopamil binding protein MRAP PF15183.6 KIK50529.1 - 0.091 12.7 0.5 0.21 11.6 0.5 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family EBP PF05241.12 KIK50529.1 - 0.35 10.3 13.4 0.54 9.7 13.4 1.5 1 1 0 1 1 1 0 Emopamil binding protein Bac_rhamnosid6H PF17389.2 KIK50530.1 - 1.6e-17 63.8 0.1 2.4e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KIK50530.1 - 6.6e-06 25.8 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KIK50530.1 - 0.00016 20.7 0.6 0.00021 20.2 0.6 1.1 1 0 0 1 1 1 1 Trehalase ABC_tran PF00005.27 KIK50531.1 - 6.6e-45 153.0 0.0 8e-21 75.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KIK50531.1 - 2.2e-23 82.1 5.4 2.2e-23 82.1 5.4 3.2 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KIK50531.1 - 8.8e-16 58.6 16.9 0.00029 20.8 0.5 4.6 3 2 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK50531.1 - 2.6e-09 36.9 0.5 0.016 14.7 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK50531.1 - 1.5e-07 31.0 0.4 0.0046 16.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK50531.1 - 4.1e-07 30.1 0.7 0.027 14.6 0.6 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KIK50531.1 - 2.9e-06 27.8 0.3 0.23 12.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 KIK50531.1 - 7.2e-06 26.0 0.1 0.19 11.6 0.0 2.9 3 0 0 3 3 3 2 NACHT domain RsgA_GTPase PF03193.16 KIK50531.1 - 1.6e-05 24.9 0.2 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KIK50531.1 - 2e-05 24.9 0.8 0.098 12.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIK50531.1 - 0.00011 22.7 2.4 0.23 11.8 0.1 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK50531.1 - 0.00014 22.2 3.3 0.83 9.9 0.3 3.9 3 2 0 3 3 3 2 AAA domain MeaB PF03308.16 KIK50531.1 - 0.00044 19.3 1.8 0.14 11.1 0.1 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KIK50531.1 - 0.0013 18.5 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIK50531.1 - 0.0014 18.8 0.3 1.5 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK50531.1 - 0.0034 17.1 0.7 0.92 9.2 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KIK50531.1 - 0.0041 17.7 0.1 0.02 15.4 0.1 4.4 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 KIK50531.1 - 0.0044 17.5 0.0 3.9 7.9 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIK50531.1 - 0.0045 16.8 10.9 0.081 12.6 0.6 3.9 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 KIK50531.1 - 0.0053 17.1 0.0 3.3 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KIK50531.1 - 0.0072 15.5 0.1 4.7 6.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 KIK50531.1 - 0.013 15.7 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KIK50531.1 - 0.017 15.0 0.1 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KIK50531.1 - 0.023 14.7 0.0 14 5.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK50531.1 - 0.027 14.5 0.2 4.9 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KIK50531.1 - 0.03 13.9 0.2 9.5 5.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KIK50531.1 - 0.037 13.5 0.1 9.1 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 KIK50531.1 - 0.046 13.6 0.2 4.3 7.2 0.0 3.2 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 KIK50531.1 - 0.048 13.8 0.2 0.048 13.8 0.2 3.7 4 1 0 4 4 3 0 Helicase HerA, central domain DUF1367 PF07105.11 KIK50531.1 - 0.05 13.3 0.1 9.6 5.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1367) DUF815 PF05673.13 KIK50531.1 - 0.053 12.7 0.0 1.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) dNK PF01712.19 KIK50531.1 - 0.075 12.9 1.7 2.6 7.9 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase SbcCD_C PF13558.6 KIK50531.1 - 0.098 12.9 1.4 3.4 8.0 0.2 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KIK50531.1 - 0.12 12.5 3.6 0.96 9.5 0.3 3.1 3 1 0 3 3 2 0 Dynamin family MobB PF03205.14 KIK50531.1 - 0.12 12.3 0.2 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 KIK50531.1 - 0.13 11.8 0.1 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 KIK50531.1 - 0.14 11.7 0.9 22 4.6 0.1 3.2 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 KIK50531.1 - 0.15 11.8 0.0 8.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-CCHC PF00098.23 KIK50535.1 - 0.0087 16.1 2.2 0.035 14.2 2.2 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.6 KIK50535.1 - 0.078 13.5 5.7 0.078 13.5 5.7 2.2 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger BacteriocIIc_cy PF12173.8 KIK50537.1 - 0.0077 16.5 6.5 0.044 14.0 4.2 2.2 2 0 0 2 2 2 2 Bacteriocin class IIc cyclic gassericin A-like ALS_ss_C PF10369.9 KIK50538.1 - 0.11 12.8 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Small subunit of acetolactate synthase TRAF6_Z2 PF18048.1 KIK50538.1 - 0.26 11.4 0.5 0.51 10.5 0.1 1.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DUF4551 PF15087.6 KIK50541.1 - 0.091 11.6 1.5 0.096 11.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FmiP_Thoc5 PF09766.9 KIK50542.1 - 0.086 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 IBN_N PF03810.19 KIK50545.1 - 7.6e-10 38.6 0.5 1.9e-07 30.9 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KIK50545.1 - 3.2e-05 24.2 3.7 0.34 11.3 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 KIK50545.1 - 0.0049 17.0 0.1 0.021 15.0 0.1 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KIK50545.1 - 0.04 14.0 3.4 0.57 10.2 0.1 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 KIK50545.1 - 0.13 12.3 2.5 1 9.4 0.2 3.4 3 1 0 3 3 3 0 Exportin 1-like protein BUD22 PF09073.10 KIK50545.1 - 0.24 10.7 3.1 0.4 10.0 3.1 1.3 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 KIK50545.1 - 4.4 6.3 10.8 7.9 5.5 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.32 KIK50548.1 - 3.6e-53 176.3 16.4 7.2e-11 42.5 0.2 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50548.1 - 1.7e-25 89.2 0.9 0.0013 19.0 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50548.1 - 7.8e-10 38.4 1.6 0.68 9.9 0.0 5.0 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50548.1 - 1.3e-08 34.2 0.2 0.32 9.9 0.0 4.8 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK50548.1 - 1.9e-06 26.5 0.0 1.4 7.1 0.0 4.4 2 2 3 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK50548.1 - 5.8e-05 22.7 3.3 15 5.4 0.1 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Pyr_redox_dim PF02852.22 KIK50548.1 - 0.00017 21.8 0.0 7.1 6.9 0.0 4.9 3 1 3 6 6 6 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF2239 PF09998.9 KIK50548.1 - 0.0003 20.6 0.0 5.3 6.8 0.0 4.7 1 1 4 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2239) DUF1652 PF07865.11 KIK50548.1 - 0.00037 20.3 0.0 26 4.7 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.16 KIK50548.1 - 0.0025 16.4 0.0 1.4 7.3 0.0 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KIK50548.1 - 0.0049 15.7 0.1 0.44 9.2 0.0 2.9 1 1 1 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 KIK50548.1 - 0.0059 16.0 0.0 25 4.0 0.0 4.3 4 1 0 5 5 5 0 WD40-like domain FCP1_C PF09309.10 KIK50548.1 - 0.0088 16.0 0.0 5.3 6.8 0.0 3.2 2 1 1 3 3 3 1 FCP1, C-terminal Me-amine-dh_H PF06433.11 KIK50548.1 - 0.048 12.5 0.0 15 4.3 0.0 2.7 1 1 2 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF5570 PF17731.1 KIK50548.1 - 1.9 8.6 6.0 33 4.6 0.1 4.1 2 2 2 4 4 4 0 Family of unknown function (DUF5570) Calici_PP_N PF08405.11 KIK50549.1 - 0.094 11.5 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal RTP1_C1 PF10363.9 KIK50550.1 - 0.035 14.3 0.3 0.14 12.4 0.1 2.0 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 AAA_9 PF12781.7 KIK50550.1 - 0.074 12.2 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region Syntaxin_2 PF14523.6 KIK50553.1 - 0.063 13.7 2.0 0.086 13.2 2.0 1.2 1 0 0 1 1 1 0 Syntaxin-like protein zf-HC5HC2H_2 PF13832.6 KIK50553.1 - 0.1 12.7 0.2 0.18 11.9 0.1 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain DUF848 PF05852.11 KIK50556.1 - 0.018 15.1 1.7 0.037 14.1 1.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) IFT57 PF10498.9 KIK50556.1 - 0.051 12.5 2.1 0.11 11.4 2.1 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4208 PF13907.6 KIK50556.1 - 0.099 13.1 1.7 0.15 12.5 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) ABC_tran_CTD PF16326.5 KIK50556.1 - 1.7 8.9 4.9 0.9 9.8 2.3 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain CxC4 PF18717.1 KIK50559.1 - 9e-47 158.2 0.0 2.3e-46 156.9 0.0 1.7 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK50559.1 - 7.6e-05 22.4 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MUG113 PF13455.6 KIK50560.1 - 5.6e-08 33.4 0.5 2.3e-07 31.4 0.0 2.3 3 1 0 3 3 3 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK50560.1 - 2.4e-05 24.8 0.0 6.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain Ank_4 PF13637.6 KIK50561.1 - 6.2e-34 115.9 2.6 2.7e-06 27.8 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK50561.1 - 5e-32 110.3 8.7 2e-13 50.7 2.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KIK50561.1 - 5.2e-23 80.4 5.0 0.0026 18.1 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KIK50561.1 - 1.5e-22 77.2 0.5 0.029 14.9 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KIK50561.1 - 6.4e-13 48.7 6.6 0.0017 18.6 0.2 5.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) DUF1966 PF09260.11 KIK50561.1 - 0.034 14.4 0.6 16 5.9 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1966) CENP-B_dimeris PF09026.10 KIK50563.1 - 6.3 7.3 13.0 0.33 11.4 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peroxidase_2 PF01328.17 KIK50565.1 - 1e-31 111.0 0.0 1.2e-31 110.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 WD40 PF00400.32 KIK50566.1 - 9.7e-35 118.0 25.3 2.8e-08 34.3 0.2 5.9 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50566.1 - 2.1e-10 40.8 1.9 0.055 13.8 0.2 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CHAP PF05257.16 KIK50566.1 - 8.8e-07 29.4 9.4 0.4 11.3 0.1 4.1 2 2 2 4 4 4 3 CHAP domain Frtz PF11768.8 KIK50566.1 - 1.9e-05 23.2 0.2 0.017 13.5 0.0 2.9 2 1 2 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK50566.1 - 2.8e-05 23.9 3.0 7 6.7 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK50566.1 - 6.6e-05 22.6 2.8 0.0073 15.9 0.5 2.2 1 1 0 2 2 2 2 PQQ-like domain Me-amine-dh_H PF06433.11 KIK50566.1 - 0.00027 19.9 0.1 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) PALB2_WD40 PF16756.5 KIK50566.1 - 0.0013 17.7 3.7 2.4 7.0 0.1 3.4 1 1 2 3 3 3 3 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 KIK50566.1 - 0.0016 17.8 1.3 10 5.3 0.1 3.4 1 1 1 3 3 3 2 WD40-like domain AlgF PF11182.8 KIK50566.1 - 0.0041 16.9 0.9 0.34 10.7 0.0 3.3 2 2 1 4 4 4 1 Alginate O-acetyl transferase AlgF DUF1258 PF06869.12 KIK50566.1 - 0.015 14.8 0.1 5.5 6.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Ge1_WD40 PF16529.5 KIK50566.1 - 0.032 13.2 3.3 3.8 6.4 0.1 3.6 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L21e PF01157.18 KIK50566.1 - 0.057 13.3 0.9 16 5.4 0.0 3.6 5 0 0 5 5 4 0 Ribosomal protein L21e Fibrinogen_aC PF12160.8 KIK50566.1 - 0.061 13.2 2.3 43 4.1 0.1 4.2 4 0 0 4 4 4 0 Fibrinogen alpha C domain DUF5114 PF17141.4 KIK50566.1 - 0.12 12.9 0.7 11 6.7 0.0 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF5114) WD40 PF00400.32 KIK50568.1 - 2.8e-61 202.0 49.1 1.3e-08 35.3 0.5 9.4 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50568.1 - 3.7e-18 65.6 12.0 0.00089 19.5 0.1 7.6 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50568.1 - 7.2e-11 42.0 7.1 0.0061 15.9 0.0 5.4 4 1 3 7 7 7 4 WD40-like domain PQQ_2 PF13360.6 KIK50568.1 - 4.5e-10 39.5 14.7 3.2e-05 23.7 1.6 4.5 2 2 2 4 4 4 3 PQQ-like domain Frtz PF11768.8 KIK50568.1 - 4.4e-07 28.6 2.9 0.97 7.7 0.0 5.7 3 1 2 6 6 6 3 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK50568.1 - 7.5e-05 21.8 0.9 0.84 8.4 0.0 4.2 1 1 4 6 6 6 2 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 KIK50568.1 - 0.00014 20.9 15.6 0.87 8.5 0.1 6.8 1 1 7 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK50568.1 - 0.0006 19.6 0.1 21 5.3 0.0 5.5 6 0 0 6 6 6 0 PQQ enzyme repeat PD40 PF07676.12 KIK50568.1 - 0.0026 17.6 4.4 75 3.4 0.0 6.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Pectate_lyase22 PF14583.6 KIK50568.1 - 0.0027 16.4 0.2 0.0093 14.7 0.1 1.9 2 0 0 2 2 2 1 Oligogalacturonate lyase PALB2_WD40 PF16756.5 KIK50568.1 - 0.011 14.7 14.4 1.7 7.5 0.1 5.7 2 2 5 7 7 7 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KIK50568.1 - 0.018 13.6 9.2 0.73 8.3 0.2 4.0 1 1 5 6 6 6 0 Cytochrome D1 heme domain B_lectin PF01453.24 KIK50568.1 - 0.043 14.4 4.9 1.2 9.7 0.2 3.5 3 2 0 3 3 3 0 D-mannose binding lectin Big_7 PF17957.1 KIK50568.1 - 0.045 14.5 18.1 5.9 7.7 0.4 6.2 4 4 1 6 6 6 0 Bacterial Ig domain DUF2019 PF09450.10 KIK50568.1 - 0.22 11.5 0.0 0.53 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) DUF5114 PF17141.4 KIK50568.1 - 0.27 11.8 2.7 45 4.7 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF5114) WD40 PF00400.32 KIK50569.1 - 1.7e-117 379.9 77.7 2e-09 37.9 0.4 15.1 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50569.1 - 7.7e-29 99.8 23.2 0.0076 16.5 0.1 13.0 1 1 13 14 14 14 9 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50569.1 - 4.7e-15 55.7 8.6 0.0059 16.0 0.1 8.4 4 3 3 9 9 9 5 WD40-like domain Frtz PF11768.8 KIK50569.1 - 3.7e-14 51.9 1.8 0.58 8.4 0.0 9.0 5 3 4 10 10 10 3 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK50569.1 - 4.9e-10 38.8 1.4 0.05 12.5 0.0 5.4 2 2 2 5 5 5 2 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 KIK50569.1 - 3e-08 33.0 18.5 1.2 8.0 0.1 10.1 1 1 11 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK50569.1 - 4.1e-06 26.8 0.0 1.3e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK50569.1 - 5.2e-05 23.1 18.5 21 5.2 0.0 10.5 12 0 0 12 12 10 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK50569.1 - 0.00087 17.9 11.1 0.23 9.9 0.2 4.7 3 2 1 5 5 5 3 Cytochrome D1 heme domain AAA_16 PF13191.6 KIK50569.1 - 0.0011 19.4 0.0 0.0038 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK50569.1 - 0.0014 17.9 0.0 0.011 15.0 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain PQQ PF01011.21 KIK50569.1 - 0.0016 18.3 1.0 1.6e+02 2.5 0.0 7.1 8 0 0 8 8 8 0 PQQ enzyme repeat AAA_18 PF13238.6 KIK50569.1 - 0.0044 17.6 0.0 0.022 15.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KIK50569.1 - 0.022 15.1 6.6 0.2 12.1 0.0 4.7 5 1 2 7 7 6 0 RNA helicase AAA PF00004.29 KIK50569.1 - 0.043 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Tuberin PF03542.16 KIK50569.1 - 0.05 12.7 0.3 0.09 11.9 0.3 1.3 1 0 0 1 1 1 0 Tuberin AAA_19 PF13245.6 KIK50569.1 - 0.065 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KIK50569.1 - 0.072 13.3 2.4 2.7 8.2 0.0 4.7 5 1 1 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK50569.1 - 0.08 13.4 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Baculo_p33 PF05214.12 KIK50569.1 - 0.1 12.4 2.2 1.7 8.4 0.1 2.3 1 1 1 2 2 2 0 Baculovirus P33 Cas_St_Csn2 PF16813.5 KIK50569.1 - 0.13 11.4 0.4 0.33 10.0 0.2 1.7 2 0 0 2 2 2 0 CRISPR-associated protein Csn2 subfamily St AAA_23 PF13476.6 KIK50569.1 - 0.37 11.3 0.0 0.37 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain P53 PF00870.18 KIK50570.1 - 0.072 12.9 0.6 0.098 12.4 0.6 1.2 1 0 0 1 1 1 0 P53 DNA-binding domain MULE PF10551.9 KIK50571.1 - 3.6e-11 43.3 0.0 8.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain WD40 PF00400.32 KIK50573.1 - 1e-126 409.1 64.5 1.5e-10 41.4 0.6 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50573.1 - 3.6e-32 110.5 18.0 0.0096 16.2 0.0 13.4 1 1 13 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50573.1 - 4.7e-16 59.0 6.2 0.025 13.9 0.0 7.5 4 3 1 8 8 8 3 WD40-like domain Frtz PF11768.8 KIK50573.1 - 3.7e-15 55.3 0.7 2 6.6 0.0 10.4 2 2 6 11 11 11 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK50573.1 - 1.9e-11 43.5 18.1 0.012 14.6 0.0 9.8 1 1 9 11 11 11 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK50573.1 - 3.6e-11 43.3 0.2 2e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Me-amine-dh_H PF06433.11 KIK50573.1 - 1.5e-10 40.5 2.5 0.11 11.3 0.0 5.3 2 2 4 6 6 6 4 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.12 KIK50573.1 - 4.4e-07 29.7 9.7 19 5.3 0.1 10.1 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat NB-ARC PF00931.22 KIK50573.1 - 4.8e-06 25.9 0.0 1.5e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK50573.1 - 1.8e-05 25.2 0.0 5.7e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK50573.1 - 3.3e-05 23.6 0.8 87 3.3 0.0 8.4 11 0 0 11 11 9 0 PQQ enzyme repeat AAA PF00004.29 KIK50573.1 - 0.00056 20.3 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK50573.1 - 0.0018 18.8 0.0 0.007 16.9 0.0 2.0 1 0 0 1 1 1 1 ABC transporter Nup160 PF11715.8 KIK50573.1 - 0.0019 16.9 11.5 0.68 8.5 0.3 6.1 3 2 3 6 6 6 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK50573.1 - 0.0042 15.7 14.2 1.3 7.5 0.1 5.2 2 1 3 6 6 6 2 Cytochrome D1 heme domain SLH PF00395.20 KIK50573.1 - 0.0047 16.9 0.0 4.2 7.5 0.0 4.2 4 0 0 4 4 4 1 S-layer homology domain RNA_helicase PF00910.22 KIK50573.1 - 0.013 15.9 3.3 0.12 12.8 0.0 4.2 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 KIK50573.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1258 PF06869.12 KIK50573.1 - 0.043 13.3 0.1 20 4.6 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1258) Torsin PF06309.11 KIK50573.1 - 0.07 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF4242 PF14026.6 KIK50573.1 - 0.09 13.0 0.0 13 6.0 0.0 4.1 4 0 0 4 4 3 0 Protein of unknown function (DUF4242) DUF87 PF01935.17 KIK50573.1 - 0.097 12.7 0.3 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 KIK50573.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK50573.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK50573.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KIK50573.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK50575.1 - 2.9e-101 328.5 70.3 5.7e-10 39.6 0.4 14.9 15 0 0 15 15 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50575.1 - 7.8e-20 71.0 19.9 0.03 14.6 0.0 11.5 1 1 12 13 13 13 8 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK50575.1 - 2.9e-09 35.8 3.3 0.11 10.7 0.0 7.1 3 2 6 9 9 9 3 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK50575.1 - 2.4e-08 34.0 0.1 1e-07 32.0 0.1 2.0 1 1 0 1 1 1 1 NACHT domain Me-amine-dh_H PF06433.11 KIK50575.1 - 2.8e-07 29.7 2.0 0.65 8.8 0.0 5.0 4 2 1 5 5 5 2 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 KIK50575.1 - 1.4e-06 27.5 19.4 0.31 10.0 0.0 9.5 2 2 8 10 10 10 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK50575.1 - 3.9e-06 26.4 9.8 0.17 11.2 0.1 6.7 2 2 4 8 8 8 1 WD40-like domain PD40 PF07676.12 KIK50575.1 - 6.7e-05 22.7 4.6 30 4.7 0.0 7.6 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK50575.1 - 0.00015 22.2 0.0 0.00044 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK50575.1 - 0.00037 19.8 0.0 0.0016 17.7 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain DUF1258 PF06869.12 KIK50575.1 - 0.00084 18.9 0.2 14 5.1 0.0 4.5 2 1 1 4 4 4 0 Protein of unknown function (DUF1258) AAA PF00004.29 KIK50575.1 - 0.0074 16.7 0.0 0.028 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK50575.1 - 0.017 15.7 0.0 0.068 13.7 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Cytochrom_D1 PF02239.16 KIK50575.1 - 0.019 13.5 13.3 0.37 9.3 0.3 4.9 2 2 2 5 5 5 0 Cytochrome D1 heme domain RNA_helicase PF00910.22 KIK50575.1 - 0.037 14.4 0.1 0.47 10.9 0.1 3.0 3 0 0 3 3 2 0 RNA helicase PQQ PF01011.21 KIK50575.1 - 0.042 13.8 0.1 1.3e+02 2.8 0.0 5.3 7 0 0 7 7 6 0 PQQ enzyme repeat NAGPA PF09992.9 KIK50575.1 - 0.042 14.0 4.0 1.4 9.1 0.1 4.3 2 1 1 4 4 4 0 Phosphodiester glycosidase AAA_23 PF13476.6 KIK50575.1 - 0.068 13.7 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK50575.1 - 0.086 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK50575.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynactin_p22 PF07426.11 KIK50576.1 - 0.03 14.2 1.1 0.044 13.6 0.1 1.7 2 0 0 2 2 2 0 Dynactin subunit p22 Rrp15p PF07890.12 KIK50576.1 - 0.075 13.4 0.3 0.3 11.4 0.0 2.2 1 1 1 2 2 2 0 Rrp15p Misat_Tub_SegII PF10644.9 KIK50577.1 - 1e-36 125.8 0.9 2.3e-36 124.7 0.1 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KIK50577.1 - 2e-27 96.1 0.1 7.5e-27 94.2 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Gti1_Pac2 PF09729.9 KIK50578.1 - 9.5e-30 104.0 0.6 3.2e-26 92.5 0.3 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family AIM3 PF17096.5 KIK50578.1 - 0.41 11.6 0.0 0.41 11.6 0.0 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Pkinase_Tyr PF07714.17 KIK50579.1 - 1.4e-48 165.5 0.0 2.1e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK50579.1 - 3.7e-28 98.6 0.0 7.6e-23 81.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 KIK50579.1 - 0.0014 18.0 0.1 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK50579.1 - 0.0034 17.0 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK50579.1 - 0.16 11.9 2.7 0.23 11.4 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK50580.1 - 7.5e-25 87.5 0.0 2.9e-20 72.4 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase DUF3243 PF11588.8 KIK50580.1 - 0.042 14.2 0.9 0.087 13.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) GPS PF01825.21 KIK50580.1 - 0.079 13.5 0.3 0.23 12.0 0.3 1.8 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif AcetylCoA_hyd_C PF13336.6 KIK50581.1 - 7.1e-12 45.5 0.0 1.2e-10 41.6 0.0 2.3 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain p450 PF00067.22 KIK50583.1 - 2.1e-63 214.7 0.0 3.3e-63 214.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIK50584.1 - 0.0027 17.6 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Methyltransf_24 PF13578.6 KIK50584.1 - 0.11 13.5 0.0 1.3 10.0 0.0 2.7 2 2 0 2 2 2 0 Methyltransferase domain DUF4724 PF15852.5 KIK50585.1 - 0.28 11.7 7.7 0.099 13.1 1.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4724) PET117 PF15786.5 KIK50588.1 - 5.9e-26 90.5 2.2 6.6e-26 90.4 2.2 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4355 PF14265.6 KIK50588.1 - 0.032 14.5 2.9 0.04 14.1 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF2514 PF10721.9 KIK50588.1 - 0.059 13.4 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4006 PF13179.6 KIK50588.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Period_C PF12114.8 KIK50588.1 - 0.16 11.5 3.5 0.2 11.2 3.5 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SCIMP PF15050.6 KIK50588.1 - 0.92 10.0 3.3 0.54 10.7 1.2 1.6 1 1 1 2 2 2 0 SCIMP protein CTD_bind PF04818.13 KIK50589.1 - 5e-07 30.4 0.0 3.5e-06 27.8 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. Paramyxo_NS_C PF02725.14 KIK50589.1 - 0.1 12.7 0.3 0.29 11.2 0.0 1.8 2 1 0 2 2 2 0 Non-structural protein C CAP59_mtransfer PF11735.8 KIK50591.1 - 1.2e-37 129.9 0.0 2.1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SIMPL PF04402.14 KIK50591.1 - 0.091 13.2 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) SNF2_N PF00176.23 KIK50592.1 - 2.8e-15 55.9 0.0 1.5e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KIK50592.1 - 3e-14 53.1 0.0 3e-14 53.1 0.0 2.8 3 1 1 4 4 4 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KIK50592.1 - 2.2e-06 28.0 0.2 1.4e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK50592.1 - 0.00044 20.3 0.1 0.25 11.4 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KIK50592.1 - 0.0014 18.6 5.6 0.0014 18.6 5.6 3.3 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK50592.1 - 0.32 10.9 8.2 1.2 9.0 8.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK50592.1 - 4.9 7.6 18.2 0.049 14.0 6.2 2.8 2 0 0 2 2 2 0 Ring finger domain zf-AN1 PF01428.16 KIK50592.1 - 8.1 6.7 9.4 1.5 9.1 5.1 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger FMN_dh PF01070.18 KIK50593.1 - 1.3e-81 274.3 0.3 3.4e-44 151.3 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KIK50593.1 - 0.00011 21.3 0.7 0.00066 18.8 0.1 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIK50593.1 - 0.0028 16.9 0.0 0.0076 15.4 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KIK50593.1 - 0.0067 15.9 0.0 0.17 11.3 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.21 KIK50593.1 - 0.051 12.8 0.3 2.8 7.1 0.0 2.8 2 1 0 3 3 3 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KIK50593.1 - 0.087 12.1 0.0 1.7 7.9 0.0 2.4 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Cript PF10235.9 KIK50594.1 - 2.1e-28 98.7 6.6 2.1e-28 98.7 6.6 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT Rhodanese_C PF12368.8 KIK50594.1 - 0.11 12.9 9.0 0.19 12.1 4.3 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal Gin PF10764.9 KIK50594.1 - 0.22 11.5 9.8 0.37 10.8 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zinc_ribbon_2 PF13240.6 KIK50594.1 - 0.27 11.0 18.0 1.6 8.6 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-dskA_traR PF01258.17 KIK50594.1 - 1.3 9.0 9.6 5.8 6.9 1.1 3.6 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger PolC_DP2 PF03833.13 KIK50594.1 - 2.8 5.7 5.7 2.6 5.8 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Methyltransf_16 PF10294.9 KIK50596.1 - 4.3e-16 59.1 0.0 7.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KIK50596.1 - 0.00033 20.2 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 KIK50596.1 - 0.00037 19.9 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G F-box-like PF12937.7 KIK50597.1 - 0.0021 17.9 9.6 0.0067 16.3 1.1 3.1 3 0 0 3 3 3 2 F-box-like Methyltransf_31 PF13847.6 KIK50598.1 - 6.9e-10 38.9 0.0 9.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK50598.1 - 4.5e-09 36.8 0.0 7.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK50598.1 - 9.4e-09 35.9 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK50598.1 - 6.3e-08 32.6 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK50598.1 - 4.1e-07 30.6 0.0 8.3e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIK50598.1 - 0.011 16.7 0.0 0.018 16.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KIK50598.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Bin3 PF06859.12 KIK50598.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) ubiquitin PF00240.23 KIK50599.1 - 1.5e-34 117.6 0.5 3.4e-34 116.4 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KIK50599.1 - 2.1e-26 91.8 2.1 2.1e-26 91.8 2.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KIK50599.1 - 3.9e-16 58.6 0.6 7.9e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK50599.1 - 2.6e-05 24.6 0.3 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK50599.1 - 0.0003 20.9 0.6 0.00068 19.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KIK50599.1 - 0.0059 17.2 0.7 0.0083 16.7 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIK50599.1 - 0.0063 16.8 0.9 0.012 15.9 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK50599.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 KIK50599.1 - 0.019 15.2 0.3 0.032 14.4 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 KIK50599.1 - 0.02 14.9 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4925 PF16272.5 KIK50599.1 - 0.099 12.1 0.2 0.14 11.6 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) KAR9 PF08580.10 KIK50602.1 - 9e-22 77.4 24.0 3.2e-20 72.3 24.0 2.7 1 1 0 1 1 1 1 Yeast cortical protein KAR9 PAPA-1 PF04795.12 KIK50602.1 - 0.0081 16.9 0.1 0.027 15.3 0.0 2.0 2 0 0 2 2 2 1 PAPA-1-like conserved region APG6_N PF17675.1 KIK50602.1 - 0.082 13.4 1.0 0.33 11.5 0.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_2 PF07719.17 KIK50603.1 - 1.3e-05 24.9 0.1 1.6 9.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK50603.1 - 1.3e-05 25.6 0.2 0.0033 17.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK50603.1 - 0.00012 22.6 2.1 3.9 8.6 0.0 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK50603.1 - 0.0036 17.9 0.0 0.038 14.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK50603.1 - 0.0038 17.5 0.6 0.068 13.6 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK50603.1 - 0.0069 16.5 0.1 0.17 12.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK50603.1 - 0.015 15.5 0.0 0.22 11.8 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4919 PF16266.5 KIK50603.1 - 0.1 12.5 0.0 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) TPR_6 PF13174.6 KIK50603.1 - 0.13 12.9 0.0 45 5.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK50603.1 - 0.14 12.5 1.0 8.6 6.7 0.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Clr2_transil PF16761.5 KIK50604.1 - 1e-20 74.3 0.1 2.1e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KIK50604.1 - 3.7e-10 40.7 0.0 3.8e-09 37.5 0.0 2.6 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Rep_fac_C PF08542.11 KIK50605.1 - 3.8e-23 81.7 0.0 1.6e-22 79.7 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KIK50605.1 - 1.4e-17 64.4 0.0 2.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIK50605.1 - 8.2e-15 55.0 0.0 9.4e-11 41.8 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KIK50605.1 - 3.6e-09 36.8 0.0 1.3e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIK50605.1 - 9.5e-07 28.7 0.0 4.4e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIK50605.1 - 5.7e-06 26.4 0.2 2.7e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KIK50605.1 - 7.1e-06 25.4 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KIK50605.1 - 1.1e-05 25.3 0.1 6.8e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIK50605.1 - 2e-05 24.8 0.1 6.3e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_16 PF13191.6 KIK50605.1 - 3.4e-05 24.3 0.0 6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIK50605.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KIK50605.1 - 0.00016 21.7 0.0 0.016 15.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK50605.1 - 0.00017 22.0 0.9 0.059 13.7 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 KIK50605.1 - 0.00021 21.6 0.4 0.21 11.9 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KIK50605.1 - 0.00026 20.8 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KIK50605.1 - 0.0004 20.2 0.3 0.0012 18.6 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DNA_pol3_delta PF06144.13 KIK50605.1 - 0.00048 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 KIK50605.1 - 0.00076 19.5 0.3 0.012 15.6 0.1 2.9 2 2 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIK50605.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK50605.1 - 0.0053 16.3 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 KIK50605.1 - 0.0061 16.0 0.1 0.1 12.0 0.1 2.2 1 1 1 2 2 2 1 Bacterial TniB protein Methyltransf_31 PF13847.6 KIK50605.1 - 0.0067 16.2 0.2 0.022 14.6 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Viral_helicase1 PF01443.18 KIK50605.1 - 0.0087 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KIK50605.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KIK50605.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KIK50605.1 - 0.035 13.2 0.0 0.077 12.0 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 KIK50605.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK50605.1 - 0.081 12.3 0.0 0.41 10.0 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 KIK50605.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain SNF2_N PF00176.23 KIK50605.1 - 0.093 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain PIF1 PF05970.14 KIK50605.1 - 0.11 11.7 0.1 2.9 7.0 0.1 2.1 1 1 0 2 2 2 0 PIF1-like helicase TPR_6 PF13174.6 KIK50605.1 - 0.28 11.9 1.1 8.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat gag_pre-integrs PF13976.6 KIK50608.1 - 2.5e-07 30.4 0.7 2.5e-07 30.4 0.7 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain APG12 PF04110.13 KIK50609.1 - 0.0012 19.2 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Dehydratase_hem PF13816.6 KIK50610.1 - 0.046 13.1 0.0 0.047 13.1 0.0 1.0 1 0 0 1 1 1 0 Haem-containing dehydratase RVP_2 PF08284.11 KIK50611.1 - 1.4e-09 37.9 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK50611.1 - 1.2e-07 32.3 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK50611.1 - 3.7e-07 30.6 0.0 6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK50611.1 - 0.018 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease SYF2 PF08231.12 KIK50612.1 - 0.085 13.2 0.1 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 SYF2 splicing factor Big_3_5 PF16640.5 KIK50613.1 - 0.0056 16.8 1.3 0.0056 16.8 1.3 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Aldedh PF00171.22 KIK50614.1 - 7.5e-08 31.3 0.0 7.8e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KIK50616.1 - 5.7e-08 31.7 0.0 0.00021 19.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Hexokinase_2 PF03727.16 KIK50618.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Hexokinase Aldedh PF00171.22 KIK50619.1 - 8.1e-69 232.3 0.0 9.2e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BsuBI_PstI_RE PF06616.11 KIK50619.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain APG12 PF04110.13 KIK50621.1 - 1e-10 41.8 0.0 1.5e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ribosomal_S8 PF00410.19 KIK50621.1 - 0.22 11.5 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S8 zf-CCHC PF00098.23 KIK50622.1 - 5.2e-06 26.3 4.5 5.2e-06 26.3 4.5 2.2 2 0 0 2 2 2 1 Zinc knuckle Aldedh PF00171.22 KIK50623.1 - 2.3e-06 26.4 0.0 3.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EVI2A PF05399.11 KIK50623.1 - 0.072 12.7 1.5 0.098 12.2 1.5 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) AvrE_T3Es PF11725.8 KIK50623.1 - 0.53 7.4 3.9 0.68 7.1 3.9 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) WD40 PF00400.32 KIK50628.1 - 4.8e-52 172.8 29.7 4.3e-08 33.7 0.2 11.3 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50628.1 - 4.6e-27 94.2 4.6 0.0072 16.6 0.1 9.2 2 2 7 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK50628.1 - 7.9e-17 61.2 4.6 0.011 14.7 0.0 6.9 3 2 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK50628.1 - 8.8e-16 57.4 5.1 0.47 10.5 0.1 9.5 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK50628.1 - 6.6e-13 49.0 0.8 5.1e-05 23.2 0.1 4.3 3 1 2 5 5 4 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK50628.1 - 1e-08 34.0 0.0 0.065 11.5 0.0 4.0 2 2 2 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK50628.1 - 2.1e-07 30.0 13.0 0.23 10.0 0.0 7.1 3 1 1 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK50628.1 - 1.9e-06 27.7 8.2 0.013 15.1 0.0 3.4 2 1 0 2 2 2 2 PQQ-like domain Gmad1 PF10647.9 KIK50628.1 - 2.4e-05 24.2 0.3 3.6 7.3 0.1 4.5 3 2 1 4 4 4 2 Lipoprotein LpqB beta-propeller domain BBS2_Mid PF14783.6 KIK50628.1 - 0.00011 22.1 0.4 0.75 9.9 0.0 4.5 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region CNH PF00780.22 KIK50628.1 - 0.00033 20.4 0.2 0.084 12.5 0.0 2.8 2 1 0 2 2 2 1 CNH domain PALB2_WD40 PF16756.5 KIK50628.1 - 0.00042 19.3 8.4 2.4 7.0 0.1 5.3 5 3 1 6 6 6 2 Partner and localizer of BRCA2 WD40 domain DPPIV_N PF00930.21 KIK50628.1 - 0.00046 19.1 0.3 2.7 6.7 0.0 4.4 4 2 1 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.6 KIK50628.1 - 0.0008 18.8 5.7 2.3 7.5 0.0 6.6 2 2 5 9 9 9 1 Neuroblastoma-amplified sequence, N terminal Rav1p_C PF12234.8 KIK50628.1 - 0.01 14.3 3.7 1.2 7.4 0.2 3.0 3 1 0 3 3 3 0 RAVE protein 1 C terminal Me-amine-dh_H PF06433.11 KIK50628.1 - 0.018 13.9 0.0 0.07 12.0 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) FCP1_C PF09309.10 KIK50628.1 - 0.02 14.8 0.0 3.7 7.4 0.0 2.5 2 1 1 3 3 3 0 FCP1, C-terminal Proteasome_A_N PF10584.9 KIK50628.1 - 0.026 14.2 13.8 13 5.6 0.0 7.1 8 0 0 8 8 7 0 Proteasome subunit A N-terminal signature PI-PLC-Y PF00387.19 KIK50628.1 - 0.029 14.7 0.5 15 5.9 0.0 3.6 3 2 2 5 5 5 0 Phosphatidylinositol-specific phospholipase C, Y domain DUF3261 PF11659.8 KIK50628.1 - 0.03 14.2 0.1 6.2 6.7 0.0 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF3261) Phytase-like PF13449.6 KIK50628.1 - 0.036 14.0 0.0 11 5.9 0.0 3.7 4 1 0 4 4 4 0 Esterase-like activity of phytase SdiA-regulated PF06977.11 KIK50628.1 - 0.047 12.9 0.0 3.7 6.7 0.0 2.9 2 1 1 3 3 3 0 SdiA-regulated GspH PF12019.8 KIK50628.1 - 0.94 9.9 6.4 37 4.8 0.4 5.2 2 1 2 4 4 4 0 Type II transport protein GspH WD40 PF00400.32 KIK50632.1 - 4.8e-38 128.5 39.8 3.9e-10 40.2 0.2 13.5 14 0 0 14 14 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50632.1 - 2.2e-25 88.7 0.0 0.023 15.0 0.0 10.9 3 3 8 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50632.1 - 4.5e-16 58.3 20.3 0.13 12.3 0.2 12.0 13 0 0 13 13 13 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50632.1 - 4e-10 39.2 10.1 0.2 10.6 0.1 9.3 6 3 4 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK50632.1 - 3.6e-08 33.3 4.9 3.9e-06 26.6 0.0 4.1 2 1 2 4 4 4 1 PQQ-like domain Frtz PF11768.8 KIK50632.1 - 3.8e-06 25.5 0.0 0.054 11.8 0.0 3.8 4 0 0 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK50632.1 - 5.1e-06 26.0 9.5 7.1 5.9 0.2 8.8 2 2 7 11 11 11 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK50632.1 - 8.5e-05 22.4 3.1 0.34 10.6 0.2 5.9 3 2 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK50632.1 - 0.00057 18.7 2.5 0.08 11.6 0.0 4.5 4 1 1 5 5 5 1 Nucleoporin Nup120/160 PQQ PF01011.21 KIK50632.1 - 0.0042 16.9 0.0 30 4.8 0.0 4.9 4 0 0 4 4 4 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 KIK50632.1 - 0.017 14.0 5.4 2.5 6.9 0.0 4.2 3 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain tify PF06200.14 KIK50632.1 - 0.035 13.4 0.0 0.42 10.0 0.0 2.4 2 0 0 2 2 2 0 tify domain WD40_like PF17005.5 KIK50632.1 - 0.11 11.8 0.2 40 3.4 0.0 3.9 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KIK50632.1 - 0.12 10.9 0.2 1.4 7.3 0.0 2.8 3 1 1 4 4 4 0 Cytochrome D1 heme domain TruB_C PF09142.11 KIK50632.1 - 0.18 11.6 0.0 16 5.3 0.0 3.7 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal Nucleoporin_FG2 PF15967.5 KIK50636.1 - 0.13 10.8 2.3 0.16 10.5 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region WD40 PF00400.32 KIK50637.1 - 7.3e-05 23.5 6.3 1.8 9.6 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ PF01011.21 KIK50637.1 - 0.00029 20.6 2.6 0.036 14.0 0.1 3.4 4 1 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 KIK50637.1 - 0.0037 16.9 0.2 0.028 14.0 0.2 2.4 1 1 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KIK50637.1 - 0.014 15.7 0.1 15 6.0 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AAA-ATPase_like PF09820.9 KIK50642.1 - 3.9e-05 23.2 0.0 4.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Predicted AAA-ATPase AAA-ATPase_like PF09820.9 KIK50643.1 - 2.6e-11 43.5 0.0 6.7e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 Predicted AAA-ATPase NERD PF08378.11 KIK50644.1 - 0.028 14.9 0.1 0.062 13.8 0.1 1.8 1 1 0 1 1 1 0 Nuclease-related domain Hjc PF01870.18 KIK50644.1 - 0.17 11.9 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) DASH_Dam1 PF08653.10 KIK50645.1 - 0.13 12.1 0.5 0.96 9.3 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 zf-C4pol PF14260.6 KIK50645.1 - 1.1 9.8 3.2 1.3 9.5 0.2 2.5 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Ribosomal_S17e PF00833.18 KIK50645.1 - 1.1 9.2 6.7 0.34 10.8 0.2 2.4 2 0 0 2 2 2 0 Ribosomal S17 Prefoldin_2 PF01920.20 KIK50645.1 - 1.9 8.5 19.4 0.058 13.3 2.4 2.8 2 1 0 2 2 2 0 Prefoldin subunit ACCA PF03255.14 KIK50645.1 - 5.5 6.9 9.5 2.5 7.9 2.4 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ax_dynein_light PF10211.9 KIK50645.1 - 9.5 6.1 22.2 8 6.4 1.7 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Paired_CXXCH_1 PF09699.10 KIK50646.1 - 0.068 12.9 2.1 0.15 11.8 2.1 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Gp-FAR-1 PF05823.12 KIK50647.1 - 4.4e-06 27.1 2.9 4.4e-06 27.1 2.9 1.9 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) OmpH PF03938.14 KIK50647.1 - 0.0025 18.1 6.8 0.0025 18.1 6.8 2.3 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) SHE3 PF17078.5 KIK50647.1 - 0.0027 17.4 11.2 0.004 16.9 11.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 TMF_DNA_bd PF12329.8 KIK50647.1 - 0.0028 17.6 11.2 0.0028 17.6 11.2 3.1 3 1 0 3 3 3 1 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KIK50647.1 - 0.0032 17.5 11.3 0.0032 17.5 11.3 2.4 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KIK50647.1 - 0.0046 16.7 14.3 0.024 14.3 10.2 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KIK50647.1 - 0.0049 16.2 7.7 0.0049 16.2 7.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 KIK50647.1 - 0.0065 16.5 15.4 0.25 11.4 7.5 3.1 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF2067 PF09840.9 KIK50647.1 - 0.0066 16.0 0.2 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) DUF4407 PF14362.6 KIK50647.1 - 0.0076 15.6 8.3 0.015 14.7 8.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) MeMO_Hyd_G PF02964.16 KIK50647.1 - 0.012 15.6 1.0 0.025 14.6 0.7 1.7 1 1 1 2 2 2 0 Methane monooxygenase, hydrolase gamma chain PKcGMP_CC PF16808.5 KIK50647.1 - 0.016 15.0 2.6 0.016 15.0 2.6 3.8 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ACCA PF03255.14 KIK50647.1 - 0.017 15.0 10.0 0.13 12.1 3.4 2.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ABC_tran_CTD PF16326.5 KIK50647.1 - 0.027 14.7 13.3 2.4 8.5 0.1 3.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain Prefoldin_2 PF01920.20 KIK50647.1 - 0.037 14.0 14.0 1.9 8.5 9.2 3.3 2 1 0 2 2 2 0 Prefoldin subunit TACC_C PF05010.14 KIK50647.1 - 0.04 13.7 13.4 0.1 12.4 4.0 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 KIK50647.1 - 0.051 13.2 14.9 0.16 11.6 14.9 1.9 1 1 0 1 1 1 0 Intermediate filament protein ING PF12998.7 KIK50647.1 - 0.078 13.6 8.5 0.3 11.7 4.1 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding FliD_C PF07195.12 KIK50647.1 - 0.11 12.0 7.7 0.075 12.4 2.1 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PRKG1_interact PF15898.5 KIK50647.1 - 0.16 12.9 14.7 1.6 9.7 4.3 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Bacillus_HBL PF05791.11 KIK50647.1 - 0.18 11.6 8.0 0.056 13.3 3.6 2.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 KIK50647.1 - 0.24 11.7 11.9 0.1 12.9 5.8 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) HMMR_N PF15905.5 KIK50647.1 - 0.26 10.7 18.9 0.072 12.6 11.6 2.2 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 KIK50647.1 - 0.27 11.6 14.0 1.5 9.2 5.7 3.1 1 1 2 3 3 3 0 Tup N-terminal YabA PF06156.13 KIK50647.1 - 0.35 11.5 14.1 0.71 10.5 4.2 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 KIK50647.1 - 0.37 10.8 10.6 4.8 7.2 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) tRNA-synt_1e PF01406.19 KIK50647.1 - 0.38 10.1 6.1 1.5 8.1 1.8 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Rx_N PF18052.1 KIK50647.1 - 0.45 10.8 7.3 1.7 9.0 1.4 3.0 1 1 2 3 3 3 0 Rx N-terminal domain DUF4618 PF15397.6 KIK50647.1 - 0.49 9.8 16.1 0.4 10.0 7.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF4164 PF13747.6 KIK50647.1 - 0.55 10.6 12.6 0.21 11.9 2.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 KIK50647.1 - 0.55 10.3 11.5 2 8.5 1.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KIK50647.1 - 0.64 10.2 10.1 1.2 9.3 5.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 KIK50647.1 - 0.73 10.5 13.5 0.9 10.2 6.9 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sugarporin_N PF11471.8 KIK50647.1 - 0.73 9.8 4.3 1.3 9.0 2.5 2.3 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Wtap PF17098.5 KIK50647.1 - 0.75 9.7 11.3 0.12 12.3 0.8 3.2 1 1 1 3 3 3 0 WTAP/Mum2p family Sec2p PF06428.11 KIK50647.1 - 0.78 9.8 17.7 0.36 10.8 1.8 3.7 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p LMBR1 PF04791.16 KIK50647.1 - 0.78 8.6 4.8 0.97 8.3 4.8 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Pox_A_type_inc PF04508.12 KIK50647.1 - 0.96 9.4 12.2 5.5 7.0 0.1 5.1 4 1 1 5 5 4 0 Viral A-type inclusion protein repeat Sipho_Gp157 PF05565.11 KIK50647.1 - 0.97 9.4 12.1 0.19 11.7 6.0 2.5 1 1 2 3 3 3 0 Siphovirus Gp157 ZapB PF06005.12 KIK50647.1 - 1.1 9.8 15.5 0.67 10.4 6.2 3.5 2 1 1 3 3 3 0 Cell division protein ZapB Cnn_1N PF07989.11 KIK50647.1 - 1.1 9.5 12.8 0.36 11.0 4.0 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Tropomyosin_1 PF12718.7 KIK50647.1 - 1.4 9.1 18.7 5.8 7.1 9.6 2.7 1 1 1 2 2 2 0 Tropomyosin like UPF0242 PF06785.11 KIK50647.1 - 1.4 9.0 17.1 31 4.6 17.0 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc24 PF08286.11 KIK50647.1 - 1.7 8.9 15.0 0.18 12.0 2.2 3.2 1 1 0 3 3 3 0 Spc24 subunit of Ndc80 CdvA PF18822.1 KIK50647.1 - 1.8 8.4 14.2 12 5.8 6.4 3.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Tweety PF04906.13 KIK50647.1 - 1.9 7.1 7.3 0.84 8.2 2.3 2.0 1 1 1 2 2 2 0 Tweety MPS2 PF17060.5 KIK50647.1 - 2.1 7.6 12.6 2.7 7.2 8.5 2.5 1 1 1 2 2 2 0 Monopolar spindle protein 2 Golgin_A5 PF09787.9 KIK50647.1 - 2.4 7.5 15.7 5.6 6.3 11.7 2.2 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 KIK50647.1 - 3 7.9 13.3 3.4 7.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Spc7 PF08317.11 KIK50647.1 - 3 6.7 16.7 2.4 6.9 10.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.6 KIK50647.1 - 3.6 8.1 12.2 21 5.6 7.8 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 KIK50647.1 - 3.8 7.3 10.9 1.3 8.9 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 KIK50647.1 - 3.8 6.8 11.3 2.1 7.6 7.6 1.9 2 0 0 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 KIK50647.1 - 4 6.9 10.5 6.7 6.2 10.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2730 PF10805.8 KIK50647.1 - 4.2 7.5 8.0 0.76 9.9 3.5 2.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.15 KIK50647.1 - 4.2 7.2 15.3 36 4.2 6.9 3.8 2 1 1 3 3 3 0 Septum formation initiator KfrA_N PF11740.8 KIK50647.1 - 4.8 7.9 10.7 5.5 7.7 2.8 3.0 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term DUF16 PF01519.16 KIK50647.1 - 5.1 7.6 11.9 2.4 8.7 5.6 2.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 Swi5 PF07061.11 KIK50647.1 - 5.1 7.3 12.7 2.3 8.4 1.5 3.4 2 1 2 4 4 4 0 Swi5 Allexi_40kDa PF05549.11 KIK50647.1 - 5.2 6.5 11.2 6.2 6.2 3.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein M PF02370.16 KIK50647.1 - 7.9 7.4 20.7 11 7.0 1.5 4.8 3 1 1 4 4 4 0 M protein repeat CSN5_C PF18323.1 KIK50647.1 - 8.9 7.3 8.3 2.6 9.0 1.1 2.7 3 1 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain FlaC_arch PF05377.11 KIK50647.1 - 9.1 6.8 11.5 5.2 7.5 0.6 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KIK50647.1 - 9.6 6.4 13.8 14 5.9 6.1 3.7 2 1 2 4 4 4 0 bZIP transcription factor APG6_N PF17675.1 KIK50647.1 - 9.7 6.7 22.1 6.6 7.3 14.4 2.9 1 1 1 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 KIK50648.1 - 0.0037 17.4 1.2 0.0044 17.2 1.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF5094 PF17015.5 KIK50648.1 - 0.068 13.3 1.3 0.087 12.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) GvpL_GvpF PF06386.11 KIK50648.1 - 0.08 12.9 0.8 0.1 12.5 0.8 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4404 PF14357.6 KIK50648.1 - 0.35 11.5 7.2 0.39 11.4 5.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ZapB PF06005.12 KIK50648.1 - 1.3 9.5 9.1 0.71 10.4 2.6 2.4 1 1 1 2 2 2 0 Cell division protein ZapB M PF02370.16 KIK50648.1 - 6.4 7.7 7.6 1.1e+02 3.9 0.5 3.7 3 1 0 3 3 3 0 M protein repeat FAM184 PF15665.5 KIK50649.1 - 0.0031 17.3 16.3 0.0038 17.1 16.3 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B TEX13 PF15186.6 KIK50649.1 - 0.004 16.9 16.5 0.012 15.3 10.8 2.0 1 1 1 2 2 2 1 Testis-expressed sequence 13 protein family Bacillus_HBL PF05791.11 KIK50649.1 - 0.0047 16.8 5.6 0.0047 16.8 5.6 2.0 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Cep57_CLD_2 PF14197.6 KIK50649.1 - 0.021 14.9 1.2 0.021 14.9 1.2 2.2 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 SHE3 PF17078.5 KIK50649.1 - 0.023 14.4 15.9 0.28 10.8 6.5 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 TPR_MLP1_2 PF07926.12 KIK50649.1 - 0.027 14.5 22.0 0.12 12.4 22.0 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DegS PF05384.11 KIK50649.1 - 0.033 13.7 12.9 0.037 13.5 4.8 2.0 1 1 1 2 2 2 0 Sensor protein DegS Spc7 PF08317.11 KIK50649.1 - 0.049 12.5 16.3 0.061 12.2 16.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KIK50649.1 - 0.055 12.9 16.6 0.073 12.5 16.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Prominin PF05478.11 KIK50649.1 - 0.056 11.4 9.6 0.07 11.1 9.6 1.1 1 0 0 1 1 1 0 Prominin YabA PF06156.13 KIK50649.1 - 0.077 13.6 15.6 0.32 11.6 4.1 2.5 1 1 2 3 3 3 0 Initiation control protein YabA Imm63 PF15599.6 KIK50649.1 - 0.12 12.8 3.1 0.31 11.4 0.5 2.2 1 1 1 2 2 2 0 Immunity protein 63 Baculo_PEP_C PF04513.12 KIK50649.1 - 0.14 12.2 4.6 0.18 11.8 4.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sas6_CC PF18594.1 KIK50649.1 - 0.17 11.7 0.4 0.17 11.7 0.4 3.7 4 0 0 4 4 3 0 Sas6/XLF/XRCC4 coiled-coil domain Jnk-SapK_ap_N PF09744.9 KIK50649.1 - 0.18 12.0 18.4 0.32 11.2 18.4 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 KIK50649.1 - 0.3 9.9 16.2 0.4 9.5 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PRKG1_interact PF15898.5 KIK50649.1 - 0.33 11.9 17.2 3.9 8.4 17.2 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain MAD PF05557.13 KIK50649.1 - 0.35 9.2 19.3 0.44 8.9 19.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FTO_NTD PF12933.7 KIK50649.1 - 0.38 10.0 6.5 0.45 9.7 6.5 1.0 1 0 0 1 1 1 0 FTO catalytic domain TSC22 PF01166.18 KIK50649.1 - 0.41 11.0 12.9 0.086 13.2 2.2 3.3 1 1 1 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 KIK50649.1 - 0.52 10.6 12.5 1.6 9.0 1.5 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 KIK50649.1 - 0.67 10.5 8.5 0.23 12.0 3.7 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 KIK50649.1 - 0.88 8.8 13.0 1.1 8.4 13.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 KIK50649.1 - 0.92 8.8 10.2 1.3 8.3 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMMR_N PF15905.5 KIK50649.1 - 1.1 8.7 21.4 13 5.2 21.4 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 KIK50649.1 - 1.2 9.8 15.5 12 6.6 1.2 3.1 1 1 2 3 3 3 0 SlyX HMMR_C PF15908.5 KIK50649.1 - 1.2 9.4 16.6 11 6.3 6.9 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF1664 PF07889.12 KIK50649.1 - 1.5 8.8 12.4 0.35 10.9 6.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KIK50649.1 - 1.9 8.8 15.3 2.1 8.6 10.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 KIK50649.1 - 2.6 6.6 11.4 3.1 6.3 11.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT20 PF14931.6 KIK50649.1 - 2.6 8.2 15.8 2.7 8.2 10.4 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 GrpE PF01025.19 KIK50649.1 - 2.7 7.6 16.8 4 7.1 4.2 2.1 1 1 1 2 2 2 0 GrpE UPF0242 PF06785.11 KIK50649.1 - 3.7 7.6 20.5 7.1 6.7 13.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CCDC-167 PF15188.6 KIK50649.1 - 3.7 8.0 14.5 3 8.3 3.7 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Ax_dynein_light PF10211.9 KIK50649.1 - 3.8 7.4 19.7 8.9 6.2 19.2 1.7 1 1 0 1 1 1 0 Axonemal dynein light chain HAUS6_N PF14661.6 KIK50649.1 - 4.8 6.7 14.0 7.5 6.1 14.0 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cluap1 PF10234.9 KIK50649.1 - 5.2 6.4 15.6 7.3 5.9 13.1 1.8 1 1 1 2 2 2 0 Clusterin-associated protein-1 Exonuc_VII_L PF02601.15 KIK50649.1 - 5.7 6.4 10.7 6.5 6.2 10.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 KIK50649.1 - 5.8 7.4 9.7 11 6.5 2.1 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Mto2_bdg PF12808.7 KIK50649.1 - 7.4 7.0 10.1 5.6 7.3 1.0 3.1 2 1 1 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Gti1_Pac2 PF09729.9 KIK50653.1 - 0.042 13.9 0.2 0.056 13.5 0.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KIK50654.1 - 1.1e-18 67.9 0.1 1.3e-18 67.8 0.1 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family F-box PF00646.33 KIK50655.1 - 0.0019 18.0 1.5 0.0049 16.7 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK50655.1 - 0.002 18.0 1.1 0.0037 17.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like Ribosomal_L37e PF01907.19 KIK50657.1 - 0.18 12.0 0.2 8.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e DUF2242 PF10001.9 KIK50661.1 - 0.033 14.4 0.0 0.034 14.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) DUF713 PF05218.14 KIK50662.1 - 0.039 13.7 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) GerE PF00196.19 KIK50663.1 - 0.092 12.3 0.1 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF1980 PF09323.10 KIK50663.1 - 0.9 9.4 4.2 1.6 8.6 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF2427 PF10348.9 KIK50665.1 - 0.0057 16.4 0.2 0.012 15.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) PKcGMP_CC PF16808.5 KIK50666.1 - 0.00081 19.2 4.5 0.65 9.9 0.6 2.8 2 1 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase KASH_CCD PF14662.6 KIK50666.1 - 0.0026 17.6 7.4 0.0028 17.5 6.4 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FAM76 PF16046.5 KIK50666.1 - 0.0041 16.5 2.6 0.006 16.0 2.6 1.2 1 0 0 1 1 1 1 FAM76 protein Phage_GP20 PF06810.11 KIK50666.1 - 0.014 15.2 3.8 1.3 8.8 0.1 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 ZapB PF06005.12 KIK50666.1 - 0.033 14.6 6.5 0.18 12.2 1.2 2.6 2 0 0 2 2 2 0 Cell division protein ZapB FtsL PF04999.13 KIK50666.1 - 0.034 14.1 1.8 0.067 13.2 1.8 1.4 1 0 0 1 1 1 0 Cell division protein FtsL DUF724 PF05266.14 KIK50666.1 - 0.038 13.8 5.1 0.076 12.8 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Peptidase_S49_N PF08496.10 KIK50666.1 - 0.042 13.9 0.4 0.078 13.0 0.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec2p PF06428.11 KIK50666.1 - 0.046 13.7 7.4 0.048 13.6 2.5 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 KIK50666.1 - 0.076 12.3 7.9 0.18 11.1 7.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KIK50666.1 - 0.079 13.3 7.5 3 8.2 0.2 2.7 1 1 0 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 KIK50666.1 - 0.083 13.0 10.2 0.14 12.2 10.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spore_III_AB PF09548.10 KIK50666.1 - 0.13 12.3 3.5 0.29 11.2 3.5 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) bZIP_1 PF00170.21 KIK50666.1 - 0.14 12.3 7.9 1.4 9.1 3.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor HMMR_N PF15905.5 KIK50666.1 - 0.17 11.3 8.7 0.49 9.8 8.7 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Med9 PF07544.13 KIK50666.1 - 0.21 11.7 4.8 0.27 11.3 0.7 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LRS4 PF10422.9 KIK50666.1 - 0.21 11.1 5.7 0.34 10.5 5.7 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ADIP PF11559.8 KIK50666.1 - 0.25 11.4 6.1 0.53 10.4 6.1 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIK50666.1 - 0.42 10.7 8.4 6 6.9 0.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KIK50666.1 - 0.48 10.6 4.1 1.9 8.6 2.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 KIK50666.1 - 0.49 10.7 7.7 15 6.0 6.9 2.7 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KIK50666.1 - 0.54 10.9 7.2 1.9 9.1 2.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 KIK50666.1 - 0.56 10.6 4.2 1.7 8.9 4.2 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Cnn_1N PF07989.11 KIK50666.1 - 1.3 9.3 9.0 0.91 9.7 3.7 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF745 PF05335.13 KIK50667.1 - 0.56 9.9 4.2 7.4 6.3 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) HR1 PF02185.16 KIK50667.1 - 2.7 8.2 6.0 1.4 9.1 2.6 2.2 2 1 0 2 2 2 0 Hr1 repeat Helitron_like_N PF14214.6 KIK50668.1 - 0.0011 19.2 0.6 0.0017 18.6 0.6 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.19 KIK50670.1 - 1.7e-13 50.6 0.0 4.1e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIK50670.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Spc7 PF08317.11 KIK50673.1 - 0.0015 17.5 8.0 0.0024 16.8 8.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein LRS4 PF10422.9 KIK50673.1 - 0.0095 15.5 5.1 0.015 14.9 5.1 1.3 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Fez1 PF06818.15 KIK50673.1 - 0.011 16.2 6.7 0.018 15.5 6.7 1.2 1 0 0 1 1 1 0 Fez1 YabA PF06156.13 KIK50673.1 - 0.013 16.1 3.0 1.7 9.3 0.3 2.4 2 0 0 2 2 2 0 Initiation control protein YabA HemX PF04375.14 KIK50673.1 - 0.026 13.8 2.5 0.048 12.9 2.5 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MPS2 PF17060.5 KIK50673.1 - 0.037 13.3 2.3 0.057 12.7 2.3 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Peptidase_S49_N PF08496.10 KIK50673.1 - 0.039 14.0 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Troponin PF00992.20 KIK50673.1 - 0.054 13.8 6.1 0.27 11.5 0.7 2.3 1 1 1 2 2 2 0 Troponin PEP-utilisers_N PF05524.13 KIK50673.1 - 0.077 13.2 1.3 0.19 11.9 1.3 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Csm1_N PF18504.1 KIK50673.1 - 0.27 11.6 12.7 0.46 10.9 3.8 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain KASH_CCD PF14662.6 KIK50673.1 - 0.29 10.9 8.9 0.56 10.0 8.9 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 KIK50673.1 - 0.32 11.0 14.9 2.2 8.3 7.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KIK50673.1 - 0.4 10.9 14.5 1.1 9.5 3.6 2.5 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 KIK50673.1 - 0.65 10.3 4.9 6 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CCDC74_C PF14917.6 KIK50673.1 - 0.71 10.4 3.5 0.81 10.2 0.9 2.2 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal FAM76 PF16046.5 KIK50673.1 - 0.77 9.1 12.0 0.042 13.2 3.6 2.4 2 1 0 2 2 2 0 FAM76 protein PKcGMP_CC PF16808.5 KIK50673.1 - 0.77 9.7 10.1 8.8 6.3 1.1 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_GP20 PF06810.11 KIK50673.1 - 0.86 9.4 6.5 0.92 9.3 0.5 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Sec2p PF06428.11 KIK50673.1 - 2.5 8.1 12.0 0.21 11.6 2.3 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Fungal_TACC PF12709.7 KIK50673.1 - 3 8.4 7.1 20 5.7 0.5 2.7 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 KIK50673.1 - 3.9 7.7 7.2 0.59 10.3 0.4 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 HMMR_N PF15905.5 KIK50673.1 - 7.1 6.0 13.6 1.9 7.9 9.4 2.0 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KIK50673.1 - 9.8 5.5 12.2 28 4.0 1.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KIK50673.1 - 9.8 6.2 11.8 2.9 8.0 3.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF648 PF04890.13 KIK50674.1 - 0.055 13.2 0.5 0.089 12.5 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) UPF0242 PF06785.11 KIK50674.1 - 0.083 13.0 5.8 0.14 12.3 5.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 KIK50674.1 - 0.12 12.1 5.2 1.9 8.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 KIK50674.1 - 1.3 9.2 4.5 16 5.7 4.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HR1 PF02185.16 KIK50674.1 - 2.9 8.1 8.0 3.3 7.9 4.6 2.6 2 1 0 2 2 2 0 Hr1 repeat WD40 PF00400.32 KIK50677.1 - 8.6e-134 431.5 72.1 1.9e-10 41.1 0.1 15.6 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50677.1 - 1.8e-60 201.2 5.9 0.00035 20.8 0.0 14.3 1 1 13 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50677.1 - 2.8e-24 84.5 17.6 0.65 10.0 0.0 14.2 14 0 0 14 14 14 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50677.1 - 8.2e-21 74.3 1.5 1 8.3 0.0 12.1 1 1 11 13 13 13 7 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK50677.1 - 3.2e-13 49.7 0.0 2.3 7.5 0.0 9.3 6 4 4 11 11 11 3 WD40-like domain eIF2A PF08662.11 KIK50677.1 - 3.6e-13 49.8 0.0 0.019 14.8 0.0 5.4 1 1 5 6 6 6 4 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK50677.1 - 1.2e-10 40.4 0.0 1 7.6 0.0 8.0 5 2 5 10 10 10 3 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK50677.1 - 3.5e-09 35.7 0.2 0.38 9.2 0.0 5.6 1 1 3 7 7 7 4 Cytochrome D1 heme domain PQQ PF01011.21 KIK50677.1 - 1.6e-05 24.6 2.3 15 5.7 0.0 8.0 9 0 0 9 9 9 0 PQQ enzyme repeat DUF4265 PF14085.6 KIK50677.1 - 1.8e-05 24.7 2.4 11 6.0 0.0 7.0 9 0 0 9 9 9 0 Domain of unknown function (DUF4265) PQQ_3 PF13570.6 KIK50677.1 - 5.5e-05 23.5 8.8 9.1 6.9 0.0 8.3 7 3 3 10 10 10 1 PQQ-like domain PQQ_2 PF13360.6 KIK50677.1 - 9.2e-05 22.1 11.6 0.069 12.7 1.0 4.6 1 1 2 4 4 4 3 PQQ-like domain Pyr_redox_dim PF02852.22 KIK50677.1 - 0.00022 21.4 0.0 41 4.5 0.0 6.3 4 1 2 7 7 7 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF2239 PF09998.9 KIK50677.1 - 0.00059 19.7 0.0 7.4 6.3 0.0 5.9 4 3 2 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2239) Me-amine-dh_H PF06433.11 KIK50677.1 - 0.016 14.1 0.0 20 3.9 0.0 4.2 5 0 0 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 KIK50677.1 - 0.079 11.6 1.8 42 2.6 0.0 5.4 8 1 0 9 9 9 0 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 KIK50677.1 - 0.095 11.5 0.0 43 2.7 0.0 4.0 2 1 2 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 KIK50677.1 - 0.12 12.1 38.5 5 6.9 0.3 11.3 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KIK50678.1 - 7.1e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK50678.1 - 1.6e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 KIK50678.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region PIF1 PF05970.14 KIK50678.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.4 2 0 0 2 2 2 1 PIF1-like helicase Parvo_NS1 PF01057.17 KIK50678.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK50678.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIK50678.1 - 0.0021 17.5 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 KIK50678.1 - 0.0042 17.4 0.0 0.0065 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK50678.1 - 0.0085 15.8 0.1 0.012 15.3 0.1 1.4 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KIK50678.1 - 0.0087 16.2 0.1 0.016 15.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK50678.1 - 0.035 13.3 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KIK50678.1 - 0.039 13.7 0.0 0.043 13.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK50678.1 - 0.068 12.9 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK50678.1 - 0.072 12.3 0.0 0.67 9.1 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.9 KIK50678.1 - 0.075 12.3 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KIK50678.1 - 0.091 12.0 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 KIK50678.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Torsin PF06309.11 KIK50678.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 KIK50678.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK50678.1 - 0.15 12.5 0.1 0.36 11.2 0.0 1.8 2 1 0 2 2 1 0 RNA helicase Cytidylate_kin PF02224.18 KIK50678.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase ATPase PF06745.13 KIK50678.1 - 0.2 11.0 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 KIK50678.1 - 0.24 10.6 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KIK50678.1 - 0.25 11.2 0.1 1.2 9.1 0.0 2.0 3 0 0 3 3 3 0 NTPase WD40 PF00400.32 KIK50679.1 - 1.3e-59 196.7 19.3 5.8e-10 39.6 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50679.1 - 1.7e-29 102.0 0.1 0.0013 19.0 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50679.1 - 2.8e-14 52.6 4.8 0.89 9.6 0.1 6.5 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50679.1 - 8.6e-09 34.8 0.0 1.7 7.5 0.0 5.6 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4072 PF13284.6 KIK50679.1 - 1.1e-05 25.8 0.9 17 5.9 0.0 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF4072) Pyr_redox_dim PF02852.22 KIK50679.1 - 1.9e-05 24.8 0.0 4.2 7.7 0.0 5.0 2 2 4 6 6 6 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Proteasome_A_N PF10584.9 KIK50679.1 - 4.3e-05 23.1 9.7 5.9 6.7 0.1 5.9 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KIK50679.1 - 0.00011 20.9 0.1 0.004 15.8 0.0 2.6 1 1 1 3 3 3 1 Cytochrome D1 heme domain DUF4265 PF14085.6 KIK50679.1 - 0.00016 21.6 0.1 7.7 6.5 0.0 5.0 4 1 2 6 6 5 1 Domain of unknown function (DUF4265) Nucleoporin_N PF08801.11 KIK50679.1 - 0.00044 19.1 0.1 0.24 10.1 0.1 3.9 1 1 2 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 KIK50679.1 - 0.00068 19.1 0.0 3.6 6.8 0.0 4.0 3 2 2 5 5 5 1 WD40-like domain PQQ PF01011.21 KIK50679.1 - 0.011 15.6 0.0 1.6e+02 2.5 0.0 5.2 6 0 0 6 6 6 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK50679.1 - 0.012 16.1 0.2 20 5.8 0.0 4.3 3 1 2 5 5 5 0 PQQ-like domain Me-amine-dh_H PF06433.11 KIK50679.1 - 0.032 13.1 0.0 2.2 7.0 0.0 2.6 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF2314 PF10077.9 KIK50679.1 - 0.035 14.2 0.0 3.2 7.8 0.0 3.5 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2314) Peptidase_S9_N PF02897.15 KIK50679.1 - 0.045 12.5 0.0 18 4.0 0.0 4.1 1 1 4 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK50679.1 - 0.079 11.3 0.0 9.7 4.4 0.0 3.4 2 2 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK50679.1 - 0.27 10.5 1.7 16 4.7 0.4 3.7 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DDE_1 PF03184.19 KIK50680.1 - 1.4e-14 54.2 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK50680.1 - 0.0077 16.0 0.0 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease CENP-T_C PF15511.6 KIK50681.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIK50681.1 - 0.011 16.0 0.2 0.02 15.2 0.2 1.6 1 1 0 1 1 1 0 CENP-S protein Histone PF00125.24 KIK50681.1 - 0.027 14.8 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK50681.1 - 0.045 14.0 0.2 0.07 13.4 0.2 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bombinin PF05298.11 KIK50681.1 - 0.071 12.8 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Bombinin TAF PF02969.17 KIK50681.1 - 0.14 12.3 0.1 0.24 11.6 0.1 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) peroxidase PF00141.23 KIK50682.1 - 1.2e-16 61.1 0.0 1.9e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase WD40 PF00400.32 KIK50683.1 - 1.3e-46 155.6 14.8 5.8e-10 39.6 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50683.1 - 3.6e-19 68.9 0.5 0.0024 18.1 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK50683.1 - 9e-08 31.9 1.0 1 9.4 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF4072 PF13284.6 KIK50683.1 - 0.00013 22.3 0.1 11 6.5 0.0 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4072) Ge1_WD40 PF16529.5 KIK50683.1 - 0.00019 20.5 0.2 5.5 5.9 0.0 4.0 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK50683.1 - 0.0008 18.3 0.0 0.37 9.5 0.0 2.3 2 1 0 2 2 2 2 Nup133 N terminal like Gmad1 PF10647.9 KIK50683.1 - 0.023 14.4 0.1 8.9 6.0 0.0 3.1 1 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF1513 PF07433.11 KIK50683.1 - 0.025 13.7 0.4 2.7 7.0 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KIK50683.1 - 0.094 11.2 0.0 0.75 8.3 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Cuticle_4 PF15955.5 KIK50683.1 - 0.14 12.9 0.1 37 5.1 0.0 3.6 4 0 0 4 4 4 0 Cuticle protein NACHT PF05729.12 KIK50684.1 - 3.8e-09 36.7 0.0 4.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK50684.1 - 6.7e-07 29.8 0.0 1.1e-06 29.1 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK50684.1 - 2.5e-06 28.0 0.0 3.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK50684.1 - 0.0026 17.3 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK50684.1 - 0.0088 15.8 0.1 0.038 13.7 0.1 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK50684.1 - 0.032 14.6 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 KIK50684.1 - 0.033 14.1 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIK50684.1 - 0.051 13.9 0.0 0.081 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK50684.1 - 0.052 12.8 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 KIK50684.1 - 0.057 13.2 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase KAP_NTPase PF07693.14 KIK50684.1 - 0.062 12.5 0.0 0.16 11.2 0.0 1.5 1 1 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KIK50684.1 - 0.081 12.6 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK50684.1 - 0.12 11.8 0.2 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KIK50684.1 - 0.12 12.9 0.0 0.16 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK50684.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 KIK50684.1 - 0.18 10.9 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain p450 PF00067.22 KIK50685.1 - 3.7e-21 75.4 0.0 4e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 gag_pre-integrs PF13976.6 KIK50686.1 - 1.1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KIK50686.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RVP_2 PF08284.11 KIK50687.1 - 0.004 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease WD40 PF00400.32 KIK50689.1 - 7.8e-37 124.7 15.8 1.1e-09 38.7 0.1 5.6 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50689.1 - 8e-14 51.7 0.1 0.0073 16.6 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK50689.1 - 4.2e-08 33.3 0.0 8.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK50689.1 - 3.7e-07 30.6 0.0 1.4e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK50689.1 - 7.8e-07 29.6 0.0 2.3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 KIK50689.1 - 8.5e-06 25.6 0.1 3.5 7.7 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IstB_IS21 PF01695.17 KIK50689.1 - 0.0087 15.8 0.1 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KIK50689.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Ge1_WD40 PF16529.5 KIK50689.1 - 0.012 14.5 0.1 5.7 5.8 0.0 3.4 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NB-ARC PF00931.22 KIK50689.1 - 0.038 13.2 0.7 0.14 11.3 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain Torsin PF06309.11 KIK50689.1 - 0.042 13.9 0.1 0.33 11.0 0.0 2.4 2 1 1 3 3 3 0 Torsin AAA_22 PF13401.6 KIK50689.1 - 0.043 14.1 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK50689.1 - 0.052 12.8 0.0 2.2 7.5 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 KIK50689.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 KIK50689.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin PF02224.18 KIK50689.1 - 0.14 11.8 0.0 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 KIK50689.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KIK50689.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.9 KIK50689.1 - 0.51 10.1 1.9 37 4.1 0.0 3.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature p450 PF00067.22 KIK50691.1 - 2e-38 132.4 0.0 1.6e-22 79.9 0.0 2.6 2 1 0 3 3 3 2 Cytochrome P450 AcetylCoA_hyd_C PF13336.6 KIK50694.1 - 4e-10 39.8 0.0 8.8e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2935 PF11155.8 KIK50695.1 - 0.09 13.1 0.0 0.26 11.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) WD40 PF00400.32 KIK50696.1 - 5.5e-130 419.5 93.5 2e-11 44.2 1.7 14.4 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50696.1 - 2.2e-39 133.7 24.8 0.0051 17.1 0.1 13.4 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50696.1 - 1.4e-20 73.9 15.4 6.6e-05 22.4 0.0 8.4 4 4 5 9 9 9 6 WD40-like domain Frtz PF11768.8 KIK50696.1 - 5.5e-11 41.5 3.0 0.15 10.4 0.0 8.5 2 2 6 9 9 9 2 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK50696.1 - 3.4e-09 36.0 2.2 0.96 8.2 0.0 5.8 3 2 2 5 5 5 3 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 KIK50696.1 - 1.9e-08 34.2 21.0 0.11 12.0 8.2 5.8 1 1 3 4 4 4 4 PQQ-like domain DUF727 PF05303.12 KIK50696.1 - 5e-06 26.5 2.0 34 4.6 0.0 7.8 2 2 7 10 10 10 0 Protein of unknown function (DUF727) Ge1_WD40 PF16529.5 KIK50696.1 - 9.3e-06 24.8 19.3 0.44 9.5 0.1 9.2 1 1 9 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK50696.1 - 2.3e-05 24.7 18.1 25 5.5 0.1 10.7 13 0 0 13 13 13 0 PQQ-like domain DUF4072 PF13284.6 KIK50696.1 - 2.9e-05 24.4 0.5 25 5.4 0.0 6.5 7 0 0 7 7 6 0 Domain of unknown function (DUF4072) DUF1258 PF06869.12 KIK50696.1 - 6.6e-05 22.5 0.0 7.2 6.0 0.0 4.7 2 2 4 6 6 6 2 Protein of unknown function (DUF1258) PD40 PF07676.12 KIK50696.1 - 9.4e-05 22.2 10.6 37 4.4 0.1 9.7 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat DUF4242 PF14026.6 KIK50696.1 - 0.00043 20.4 0.0 17 5.6 0.0 5.7 6 1 1 7 7 7 0 Protein of unknown function (DUF4242) Kelch_6 PF13964.6 KIK50696.1 - 0.024 14.9 13.9 12 6.3 0.1 7.3 9 0 0 9 9 7 0 Kelch motif LRR_10 PF18805.1 KIK50696.1 - 0.037 13.7 6.5 3.7 7.3 0.0 6.4 6 3 1 7 7 7 0 Leucine-rich repeat Coat_X PF07552.11 KIK50696.1 - 0.22 11.4 4.7 15 5.5 0.1 4.5 5 0 0 5 5 5 0 Spore Coat Protein X and V domain Asp_decarbox PF02261.16 KIK50696.1 - 0.63 10.0 1.8 14 5.6 0.0 4.2 5 3 2 7 7 6 0 Aspartate decarboxylase DUF4939 PF16297.5 KIK50700.1 - 3.3e-05 23.7 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) GRP PF07172.11 KIK50700.1 - 0.66 10.7 16.2 1.1 10.1 16.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family DUF4489 PF14879.6 KIK50703.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) RVP_2 PF08284.11 KIK50705.1 - 4.2e-11 42.8 0.0 7.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK50705.1 - 7.2e-07 29.8 0.1 1.8e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK50705.1 - 2.8e-06 27.8 0.0 6.5e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 KIK50705.1 - 0.0054 16.3 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase DUF3443 PF11925.8 KIK50705.1 - 0.016 14.1 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Asp_protease PF09668.10 KIK50705.1 - 0.04 13.7 0.0 0.18 11.6 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease DUF908 PF06012.12 KIK50706.1 - 0.13 11.6 1.3 0.15 11.5 1.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Retrotrans_gag PF03732.17 KIK50707.1 - 0.022 15.0 0.0 0.025 14.8 0.0 1.0 1 0 0 1 1 1 0 Retrotransposon gag protein DUF5637 PF18687.1 KIK50709.1 - 0.051 13.6 4.6 0.068 13.2 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5637) AcetylCoA_hyd_C PF13336.6 KIK50711.1 - 1.9e-40 138.3 0.0 3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK50711.1 - 2e-23 83.4 0.0 3.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain WD40 PF00400.32 KIK50712.1 - 1.1e-122 396.4 81.2 1.1e-10 41.9 1.3 14.7 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50712.1 - 6.8e-40 135.3 26.5 0.013 15.8 0.1 13.1 1 1 12 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50712.1 - 1.1e-16 61.0 15.7 0.0019 17.6 0.0 8.6 4 3 3 8 8 8 5 WD40-like domain Cytochrom_D1 PF02239.16 KIK50712.1 - 6.7e-09 34.7 17.5 0.0021 16.7 0.3 5.0 4 1 1 5 5 5 4 Cytochrome D1 heme domain Frtz PF11768.8 KIK50712.1 - 1.6e-07 30.1 3.7 13 3.9 0.0 8.2 3 2 5 10 10 10 0 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK50712.1 - 1.6e-07 31.4 0.0 3.7e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 NACHT domain PQQ_3 PF13570.6 KIK50712.1 - 1.5e-06 28.5 12.4 3.2 8.4 0.1 8.6 9 0 0 9 9 9 1 PQQ-like domain Ge1_WD40 PF16529.5 KIK50712.1 - 1.8e-05 23.9 24.3 0.3 10.0 1.8 9.0 1 1 7 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK50712.1 - 2.7e-05 24.6 0.0 6.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF727 PF05303.12 KIK50712.1 - 0.00014 21.9 1.8 25 5.0 0.0 6.1 4 1 1 6 6 6 0 Protein of unknown function (DUF727) NB-ARC PF00931.22 KIK50712.1 - 0.00048 19.4 0.0 0.00094 18.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF1258 PF06869.12 KIK50712.1 - 0.00054 19.5 0.9 29 4.0 0.0 5.3 4 2 1 5 5 5 0 Protein of unknown function (DUF1258) PD40 PF07676.12 KIK50712.1 - 0.0026 17.7 11.5 71 3.5 0.1 9.0 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Robl_LC7 PF03259.17 KIK50712.1 - 0.0034 17.1 2.9 7.3 6.5 0.0 5.4 7 0 0 7 7 7 1 Roadblock/LC7 domain Kelch_6 PF13964.6 KIK50712.1 - 0.0065 16.7 18.1 10 6.6 0.2 7.0 7 0 0 7 7 6 0 Kelch motif RNA_helicase PF00910.22 KIK50712.1 - 0.059 13.8 0.0 0.41 11.0 0.0 2.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KIK50712.1 - 0.062 13.8 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIK50712.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 KIK50712.1 - 0.15 12.5 0.0 0.42 11.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DCX PF03607.17 KIK50712.1 - 0.18 11.9 3.6 1.4e+02 2.7 0.0 5.8 7 0 0 7 7 7 0 Doublecortin Big_7 PF17957.1 KIK50712.1 - 5.9 7.7 27.0 22 5.9 1.7 8.9 7 3 4 11 11 11 0 Bacterial Ig domain Cytomega_UL20A PF05984.12 KIK50715.1 - 1.4 9.3 6.4 44 4.5 0.1 3.4 2 1 1 3 3 3 0 Cytomegalovirus UL20A protein Peptidase_U57 PF05582.12 KIK50716.1 - 0.085 12.1 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Cupin_4 PF08007.12 KIK50716.1 - 0.095 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 KIK50716.1 - 0.1 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase WD40 PF00400.32 KIK50718.1 - 0.0007 20.4 5.9 0.037 14.9 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50718.1 - 0.015 15.5 0.0 48 4.3 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK50718.1 - 0.18 11.4 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 PQQ-like domain SHMT PF00464.19 KIK50720.1 - 0.018 13.7 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase PPP4R2 PF09184.11 KIK50722.1 - 0.0063 16.1 23.6 0.0063 16.1 23.6 1.8 2 0 0 2 2 2 1 PPP4R2 Mpp10 PF04006.12 KIK50722.1 - 0.021 13.3 31.8 0.025 13.1 31.8 1.1 1 0 0 1 1 1 0 Mpp10 protein VIR_N PF15912.5 KIK50722.1 - 0.5 9.9 14.3 0.79 9.3 14.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Nop14 PF04147.12 KIK50722.1 - 1.1 7.4 38.0 1.5 7.0 38.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 KIK50722.1 - 1.5 8.1 11.8 3.1 7.1 11.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPR3 PF03666.13 KIK50722.1 - 6.4 5.4 13.3 9.5 4.9 13.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SHMT PF00464.19 KIK50723.1 - 1.1e-05 24.3 0.0 2.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydroxymethyltransferase F-box PF00646.33 KIK50724.1 - 1.9e-05 24.4 0.8 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK50724.1 - 0.00014 21.7 0.4 0.0014 18.5 0.0 2.5 3 0 0 3 3 3 1 F-box-like zf-RING_UBOX PF13445.6 KIK50725.1 - 4.4e-09 36.2 3.8 4.4e-09 36.2 3.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK50725.1 - 1.4e-08 34.7 10.2 3.5e-08 33.5 10.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK50725.1 - 2e-08 34.0 8.7 7.4e-08 32.1 8.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK50725.1 - 3.8e-08 33.1 6.3 3.8e-08 33.1 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK50725.1 - 4.2e-08 32.9 4.1 4.2e-08 32.9 4.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK50725.1 - 4.4e-08 32.9 5.6 1.4e-07 31.4 5.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK50725.1 - 6.3e-08 32.8 6.2 6.3e-08 32.8 6.2 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KIK50725.1 - 0.00016 21.5 6.9 0.0026 17.6 7.3 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIK50725.1 - 0.011 15.5 3.7 0.011 15.5 3.7 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KIK50725.1 - 0.023 15.0 4.4 0.023 15.0 4.4 2.7 3 1 0 3 3 3 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KIK50725.1 - 0.044 13.6 6.3 3.2 7.6 7.8 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIK50725.1 - 0.92 9.6 5.5 0.62 10.2 3.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KIK50725.1 - 1.7 8.6 7.5 17 5.4 7.5 2.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein NEMO PF11577.8 KIK50727.1 - 0.012 15.6 5.3 0.03 14.3 5.3 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO ZapB PF06005.12 KIK50727.1 - 0.7 10.4 8.1 0.066 13.7 3.0 1.9 2 0 0 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 KIK50727.1 - 5.7 7.0 8.2 0.42 10.6 2.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding JIP_LZII PF16471.5 KIK50727.1 - 8.9 6.6 7.5 1.5 9.1 2.5 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CCDC106 PF15794.5 KIK50729.1 - 0.25 11.0 8.0 0.41 10.3 8.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SASA PF03629.18 KIK50730.1 - 0.013 15.1 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase NACHT PF05729.12 KIK50732.1 - 1.1e-05 25.4 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK50732.1 - 1.1e-05 25.9 0.0 1.3e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK50732.1 - 0.0003 20.8 0.0 0.00035 20.6 0.0 1.0 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK50732.1 - 0.00071 18.8 0.0 0.00083 18.6 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK50732.1 - 0.002 18.7 0.1 0.0029 18.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK50732.1 - 0.0037 17.0 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KIK50732.1 - 0.0048 16.6 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 KIK50732.1 - 0.0065 16.9 0.4 0.023 15.1 0.4 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK50732.1 - 0.0083 16.4 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK50732.1 - 0.011 16.2 0.1 0.028 14.8 0.0 1.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KIK50732.1 - 0.011 16.2 0.0 0.016 15.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KIK50732.1 - 0.031 14.2 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 KIK50732.1 - 0.037 14.2 0.1 0.047 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KIK50732.1 - 0.068 12.5 0.1 0.086 12.2 0.1 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 KIK50732.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIK50732.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 KaiC PIF1 PF05970.14 KIK50732.1 - 0.095 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_24 PF13479.6 KIK50732.1 - 0.16 11.6 2.2 0.45 10.2 2.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK50732.1 - 7.6 7.0 6.1 1.7 9.1 0.3 2.0 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 KIK50733.1 - 5.5e-33 112.5 13.8 2.8e-09 37.5 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50733.1 - 3.9e-13 49.5 0.0 0.0038 17.5 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIK50733.1 - 1.3e-05 25.1 0.7 0.19 11.4 0.0 3.8 1 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 KIK50733.1 - 0.00015 21.6 1.5 0.46 10.5 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK50733.1 - 0.00043 19.7 0.0 0.64 9.3 0.0 3.1 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KIK50733.1 - 0.002 17.2 0.1 7.7 5.4 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4265 PF14085.6 KIK50733.1 - 0.0065 16.4 0.3 3.1 7.8 0.1 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4265) Nup160 PF11715.8 KIK50733.1 - 0.0066 15.1 0.0 20 3.7 0.0 3.7 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Cuticle_4 PF15955.5 KIK50733.1 - 0.014 16.1 0.7 15 6.4 0.0 3.9 4 0 0 4 4 4 0 Cuticle protein PQQ_3 PF13570.6 KIK50733.1 - 0.04 14.4 0.2 2.9 8.5 0.0 3.4 2 1 2 4 4 4 0 PQQ-like domain Retrotran_gag_2 PF14223.6 KIK50734.1 - 4e-12 46.0 0.0 4.6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FAP PF07174.11 KIK50737.1 - 0.016 14.7 6.1 0.016 14.7 6.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HTH_12 PF08461.10 KIK50739.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Retrotran_gag_2 PF14223.6 KIK50740.1 - 9e-05 22.2 0.1 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK50740.1 - 0.0026 17.4 1.6 0.005 16.5 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) HTH_Tnp_Tc3_2 PF01498.18 KIK50741.1 - 0.001 19.3 0.0 0.008 16.4 0.0 1.9 1 1 1 2 2 2 1 Transposase Arg_repressor PF01316.21 KIK50741.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_33 PF13592.6 KIK50741.1 - 0.012 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix DUF4376 PF14301.6 KIK50742.1 - 0.079 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DivIC PF04977.15 KIK50747.1 - 0.0054 16.5 0.6 0.01 15.6 0.6 1.4 1 0 0 1 1 1 1 Septum formation initiator DUF1388 PF07142.12 KIK50747.1 - 4.8 7.2 7.5 10 6.1 7.5 1.6 1 1 0 1 1 1 0 Repeat of unknown function (DUF1388) YL1 PF05764.13 KIK50748.1 - 0.0045 17.1 8.8 0.0071 16.5 8.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Polyoma_lg_T_C PF06431.11 KIK50748.1 - 0.021 13.7 2.3 0.033 13.1 2.3 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CDC45 PF02724.14 KIK50748.1 - 0.061 11.6 8.7 0.084 11.2 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KIK50748.1 - 0.061 12.7 9.8 0.094 12.0 9.8 1.3 1 0 0 1 1 1 0 BUD22 YqfQ PF14181.6 KIK50748.1 - 0.54 10.4 3.9 0.82 9.8 3.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein FUSC-like PF12805.7 KIK50749.1 - 0.0071 15.5 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS Asp_protease_2 PF13650.6 KIK50749.1 - 0.048 14.3 0.0 0.096 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KIK50749.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.26 KIK50752.1 - 0.082 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HSP70 PF00012.20 KIK50753.1 - 4.6e-261 867.3 7.7 5.2e-261 867.1 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK50753.1 - 6.6e-20 71.2 0.8 1.6e-17 63.4 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 KIK50753.1 - 0.0066 15.5 0.4 0.32 9.9 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KIK50753.1 - 0.0073 15.6 0.2 0.023 14.0 0.2 1.9 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KIK50753.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Spectrin PF00435.21 KIK50753.1 - 0.23 11.9 6.8 4 8.0 0.1 3.5 3 1 0 3 3 3 0 Spectrin repeat FIVAR PF07554.13 KIK50753.1 - 0.29 11.9 1.2 2.3 9.0 0.1 3.0 4 0 0 4 4 4 0 FIVAR domain Glyco_hydro_39 PF01229.17 KIK50754.1 - 0.031 12.9 0.1 0.043 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 MIP PF00230.20 KIK50755.1 - 9.2e-30 104.0 6.5 1.8e-29 103.0 6.4 1.4 1 1 0 1 1 1 1 Major intrinsic protein FAD_binding_3 PF01494.19 KIK50756.1 - 6e-23 81.6 0.0 7.2e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK50756.1 - 7.8e-06 26.0 0.4 2.2e-05 24.6 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK50756.1 - 0.00014 21.6 0.5 0.00073 19.2 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK50756.1 - 0.00022 20.6 0.6 0.013 14.8 0.4 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK50756.1 - 0.00091 18.2 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 KIK50756.1 - 0.0018 17.0 0.3 0.18 10.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KIK50756.1 - 0.0024 17.2 0.0 0.76 9.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK50756.1 - 0.0046 17.0 0.2 0.63 10.0 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KIK50756.1 - 0.057 12.7 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIK50756.1 - 0.06 13.9 1.2 1.8 9.2 0.6 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK50756.1 - 0.085 11.9 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KIK50756.1 - 0.21 10.6 0.1 1.2 8.2 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK50757.1 - 0.00021 21.5 0.2 0.00044 20.4 0.2 1.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK50757.1 - 0.2 10.4 0.1 0.21 10.4 0.1 1.0 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK50758.1 - 1.8e-15 57.1 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DBD_Tnp_Hermes PF10683.9 KIK50758.1 - 0.16 11.7 0.3 3 7.6 0.1 2.7 2 1 0 2 2 2 0 Hermes transposase DNA-binding domain Sugar_tr PF00083.24 KIK50759.1 - 2.7e-107 359.4 19.0 3.5e-107 359.1 19.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK50759.1 - 6.8e-29 100.9 29.7 6.8e-29 100.9 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK50759.1 - 4.7e-05 22.0 1.5 9.9e-05 20.9 1.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIK50759.1 - 0.0034 15.8 0.5 0.0034 15.8 0.5 2.8 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family Aldo_ket_red PF00248.21 KIK50760.1 - 6.3e-37 127.4 0.0 4.6e-35 121.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TetR_C_5 PF08360.11 KIK50760.1 - 0.14 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 QacR-like protein, C-terminal region COesterase PF00135.28 KIK50761.1 - 2e-83 281.0 0.0 2.5e-82 277.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK50761.1 - 0.014 14.8 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIK50761.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KIK50762.1 - 5.7e-19 68.4 0.0 6.8e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family F-box-like PF12937.7 KIK50763.1 - 1.8e-11 43.8 5.4 1.9e-09 37.3 1.6 3.6 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KIK50763.1 - 0.0025 17.6 1.2 0.015 15.2 1.2 2.5 1 1 0 1 1 1 1 F-box domain HAUS-augmin3 PF14932.6 KIK50763.1 - 0.068 12.7 0.3 0.068 12.7 0.3 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 KIK50763.1 - 0.084 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 KIK50763.1 - 0.16 12.2 0.1 0.75 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 KIK50763.1 - 0.23 11.9 0.7 1.1 9.6 0.4 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 KIK50763.1 - 0.28 11.4 2.4 5 7.4 0.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PS_Dcarbxylase PF02666.15 KIK50764.1 - 7.6e-50 169.2 0.0 1.2e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Methyltransf_16 PF10294.9 KIK50771.1 - 2.3e-20 73.0 0.0 2.4e-12 46.9 0.0 3.1 2 1 0 2 2 2 2 Lysine methyltransferase DUF2605 PF10792.9 KIK50773.1 - 0.033 14.1 1.7 5.4 7.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) CHASE3 PF05227.13 KIK50773.1 - 0.057 13.3 1.0 0.11 12.4 0.5 1.6 1 1 1 2 2 2 0 CHASE3 domain Synaptonemal_3 PF15191.6 KIK50773.1 - 0.075 12.8 0.5 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 HET-S PF17108.5 KIK50774.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic F-box-like PF12937.7 KIK50774.1 - 0.1 12.5 9.0 0.03 14.2 4.9 2.4 2 1 0 2 2 2 0 F-box-like F-box PF00646.33 KIK50774.1 - 3.8 7.5 6.0 4.6 7.2 1.5 3.2 3 1 0 3 3 3 0 F-box domain DUF929 PF06053.11 KIK50775.1 - 0.084 12.2 3.5 0.67 9.2 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF929) YccF PF03733.13 KIK50775.1 - 0.19 12.5 0.0 0.19 12.5 0.0 3.1 3 0 0 3 3 3 0 Inner membrane component domain FAD-oxidase_C PF02913.19 KIK50778.1 - 4e-57 193.7 0.0 5.5e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK50778.1 - 1.6e-21 76.5 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 KIK50781.1 - 8.3e-54 183.0 0.0 1.3e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK50781.1 - 1.5e-34 119.6 0.0 2.7e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK50781.1 - 0.047 13.9 0.1 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK50781.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_4 PF07993.12 KIK50782.1 - 1.2e-32 113.1 0.0 1.8e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK50782.1 - 3.1e-28 98.5 0.0 1.6e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK50782.1 - 4.1e-11 42.8 0.0 1.8e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK50782.1 - 1.2e-06 28.8 0.0 3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIK50782.1 - 0.0016 18.4 0.1 0.008 16.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KIK50782.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KIK50782.1 - 0.034 14.6 0.0 0.094 13.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 KIK50783.1 - 2.1e-32 112.4 30.2 2.1e-32 112.4 30.2 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK50783.1 - 6.6e-06 25.7 3.2 6.6e-06 25.7 3.2 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CbiQ PF02361.16 KIK50783.1 - 0.091 12.4 11.1 0.016 14.9 6.2 2.1 2 0 0 2 2 2 0 Cobalt transport protein AAA_16 PF13191.6 KIK50784.1 - 4.7e-05 23.8 0.0 5.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK50784.1 - 0.0018 18.2 0.1 0.0054 16.7 0.1 1.8 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK50784.1 - 0.0019 18.2 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK50784.1 - 0.0034 17.7 0.0 0.0081 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK50784.1 - 0.0046 17.3 0.0 0.0063 16.9 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KIK50784.1 - 0.022 15.3 0.0 0.029 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK50784.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 KIK50784.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KIK50784.1 - 0.17 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KIK50784.1 - 0.21 11.3 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain GMC_oxred_N PF00732.19 KIK50786.1 - 2.1e-40 139.0 0.0 2.9e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK50786.1 - 2.8e-31 109.0 0.0 5.2e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.13 KIK50787.1 - 1.1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK50787.1 - 1.4e-10 40.7 0.5 7.6e-10 38.3 0.5 1.8 1 1 0 1 1 1 1 Carboxylesterase family PGAP1 PF07819.13 KIK50787.1 - 0.013 15.3 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KIK50787.1 - 0.017 15.8 0.1 0.05 14.2 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KIK50787.1 - 0.025 13.4 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase MFS_1 PF07690.16 KIK50788.1 - 4.1e-10 39.1 8.0 4.1e-10 39.1 8.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF389 PF04087.14 KIK50788.1 - 0.016 15.2 8.4 0.023 14.7 3.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF389) FtsX PF02687.21 KIK50788.1 - 6.9 7.2 13.2 7.8e+02 0.6 13.2 2.5 1 1 0 1 1 1 0 FtsX-like permease family Aminotran_5 PF00266.19 KIK50789.1 - 2.3e-12 46.6 0.0 3.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK50789.1 - 0.00025 20.5 0.1 0.0032 16.8 0.1 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIK50789.1 - 0.014 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TMEM192 PF14802.6 KIK50790.1 - 0.049 12.7 0.4 0.088 11.9 0.4 1.4 1 0 0 1 1 1 0 TMEM192 family Ferlin_C PF16165.5 KIK50790.1 - 9.1 6.2 6.7 31 4.5 1.5 2.4 2 0 0 2 2 2 0 Ferlin C-terminus ADH_zinc_N PF00107.26 KIK50791.1 - 1.7e-18 66.8 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK50791.1 - 4.6e-05 24.5 0.0 7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 KIK50791.1 - 0.08 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Phage_holin_5_2 PF16079.5 KIK50796.1 - 0.16 12.3 2.4 0.27 11.6 2.4 1.5 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V GMC_oxred_N PF00732.19 KIK50799.1 - 6.3e-09 35.6 0.0 6.9e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK50799.1 - 3.2e-05 24.1 0.3 3.9e-05 23.8 0.3 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK50799.1 - 0.00014 21.1 0.8 0.00016 20.9 0.8 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK50799.1 - 0.00017 21.3 0.3 0.0002 21.0 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK50799.1 - 0.00037 19.8 0.1 0.00039 19.8 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK50799.1 - 0.00046 19.4 0.1 0.00054 19.1 0.1 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.18 KIK50799.1 - 0.00046 20.4 0.2 0.00055 20.2 0.2 1.1 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.14 KIK50799.1 - 0.00055 18.9 0.4 0.00059 18.8 0.4 1.0 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK50799.1 - 0.002 17.4 0.1 0.0022 17.3 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK50799.1 - 0.0042 16.4 0.1 0.0045 16.2 0.1 1.0 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KIK50799.1 - 0.0074 16.8 0.6 0.0082 16.7 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK50799.1 - 0.011 14.5 0.1 0.012 14.3 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK50799.1 - 0.013 14.7 0.6 0.015 14.5 0.6 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KIK50799.1 - 0.024 15.2 0.1 0.027 15.1 0.1 1.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 KIK50799.1 - 0.061 12.4 0.2 0.063 12.3 0.2 1.0 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KIK50799.1 - 0.064 13.3 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIK50799.1 - 0.11 12.2 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KIK50799.1 - 0.18 11.1 0.8 0.21 10.9 0.8 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KIK50800.1 - 6.3e-43 147.2 0.0 8e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK50800.1 - 7.3e-31 107.6 0.0 1.6e-30 106.6 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase p450 PF00067.22 KIK50801.1 - 7.3e-80 268.9 0.0 8.7e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CitMHS PF03600.16 KIK50801.1 - 0.18 11.0 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter TMEM192 PF14802.6 KIK50803.1 - 0.014 14.5 0.2 0.038 13.1 0.2 1.7 1 0 0 1 1 1 0 TMEM192 family DUF3007 PF11460.8 KIK50803.1 - 2.6 8.4 4.7 13 6.1 0.4 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3007) Aminotran_5 PF00266.19 KIK50804.1 - 1.8e-09 37.0 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF2729 PF10870.8 KIK50805.1 - 0.49 10.3 5.9 0.12 12.2 3.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) ACPS PF01648.20 KIK50806.1 - 9.4e-10 38.6 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ycf15 PF10705.9 KIK50808.1 - 0.028 14.6 0.9 0.046 13.9 0.9 1.4 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative CSS-motif PF12792.7 KIK50810.1 - 0.02 14.4 0.8 0.08 12.4 0.1 2.1 2 0 0 2 2 2 0 CSS motif domain associated with EAL WD40 PF00400.32 KIK50813.1 - 1.4e-05 25.7 2.2 17 6.5 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK50813.1 - 0.00012 21.8 0.8 0.019 14.6 0.1 2.9 1 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KIK50813.1 - 0.00023 20.9 2.5 0.036 14.0 0.1 3.4 3 1 0 3 3 3 2 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 KIK50813.1 - 0.0028 17.9 0.0 1.6 9.1 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain XPG_I PF00867.18 KIK50814.1 - 1.3e-10 41.4 0.1 2.5e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 XPG I-region AAA-ATPase_like PF09820.9 KIK50817.1 - 1.3e-10 41.2 0.0 3.2e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Predicted AAA-ATPase FlxA PF14282.6 KIK50819.1 - 0.021 14.8 14.3 0.1 12.6 1.4 2.5 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_S17e PF00833.18 KIK50819.1 - 0.077 12.9 0.4 0.077 12.9 0.4 2.1 2 0 0 2 2 2 0 Ribosomal S17 Seryl_tRNA_N PF02403.22 KIK50819.1 - 0.079 13.2 16.3 0.21 11.9 6.9 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rab5-bind PF09311.11 KIK50819.1 - 0.12 11.7 14.9 0.59 9.5 0.8 2.2 2 0 0 2 2 2 0 Rabaptin-like protein DASH_Dam1 PF08653.10 KIK50819.1 - 0.24 11.2 0.5 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 F_actin_bind PF08919.10 KIK50819.1 - 0.41 10.8 5.1 1.7 8.8 0.8 2.7 3 0 0 3 3 3 0 F-actin binding DUF2250 PF10007.9 KIK50819.1 - 0.56 10.4 5.0 4.5 7.4 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2408 PF10303.9 KIK50819.1 - 0.69 10.5 11.3 4.9 7.7 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Spc24 PF08286.11 KIK50819.1 - 0.74 10.1 9.8 7 6.9 0.3 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.6 KIK50819.1 - 2.4 8.6 20.3 1.3 9.5 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-C4pol PF14260.6 KIK50819.1 - 2.5 8.6 4.1 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CorA PF01544.18 KIK50819.1 - 2.9 7.1 7.4 5.7 6.2 0.2 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 KIK50819.1 - 7.2 6.6 21.6 0.084 12.8 2.3 3.2 3 1 0 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.9 KIK50819.1 - 9.9 6.1 17.0 13 5.6 1.4 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain zf-RING_UBOX PF13445.6 KIK50821.1 - 7.1e-08 32.3 4.3 7.1e-08 32.3 4.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK50821.1 - 1e-06 28.5 10.1 1.6e-06 27.9 10.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK50821.1 - 7.8e-06 25.7 10.3 1.3e-05 24.9 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK50821.1 - 8e-06 25.6 7.4 2.3e-05 24.2 7.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK50821.1 - 8.6e-06 25.8 11.5 1.3e-05 25.2 11.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK50821.1 - 1e-05 25.8 10.3 1.7e-05 25.1 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK50821.1 - 0.00012 21.8 9.9 0.00026 20.8 9.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK50821.1 - 0.3 11.0 11.1 0.87 9.5 10.5 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Peptidase_C48 PF02902.19 KIK50822.1 - 1.3e-11 44.8 0.2 2.7e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Gp-FAR-1 PF05823.12 KIK50822.1 - 0.00017 21.9 2.5 0.00017 21.9 2.5 1.8 1 1 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MeMO_Hyd_G PF02964.16 KIK50822.1 - 0.0025 17.9 0.4 0.0051 16.8 0.4 1.6 1 0 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain Yuri_gagarin PF15934.5 KIK50822.1 - 0.022 14.6 8.7 1 9.2 0.2 2.3 1 1 0 2 2 2 0 Yuri gagarin ACCA PF03255.14 KIK50822.1 - 0.054 13.4 7.2 0.54 10.1 1.6 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4407 PF14362.6 KIK50822.1 - 0.099 12.0 6.7 0.18 11.1 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KIK50822.1 - 0.27 11.3 16.6 1.9 8.6 7.3 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 KIK50822.1 - 0.3 11.1 13.4 3.7 7.6 5.4 3.3 3 0 0 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.8 KIK50822.1 - 0.38 10.8 18.8 0.076 13.0 10.9 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 KIK50822.1 - 0.4 10.6 4.7 13 5.8 0.0 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FliD_C PF07195.12 KIK50822.1 - 0.67 9.3 5.8 0.31 10.4 2.2 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CENP-F_leu_zip PF10473.9 KIK50822.1 - 0.97 9.5 19.5 0.13 12.3 12.1 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 KIK50822.1 - 1.3 9.3 11.1 0.6 10.4 5.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) OmpH PF03938.14 KIK50822.1 - 1.8 8.9 17.8 0.029 14.7 5.9 2.6 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) Lebercilin PF15619.6 KIK50822.1 - 2.1 8.0 21.4 0.044 13.4 9.6 2.4 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.10 KIK50822.1 - 2.2 8.6 15.7 4.7 7.6 1.6 3.2 1 1 2 3 3 3 0 Tup N-terminal PKcGMP_CC PF16808.5 KIK50822.1 - 3.5 7.6 16.4 0.042 13.7 2.6 3.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IFP_35_N PF07334.13 KIK50822.1 - 3.9 7.6 7.1 1.9 8.6 3.2 2.3 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YabA PF06156.13 KIK50822.1 - 4.7 7.9 15.4 3.4 8.4 4.5 3.4 1 1 2 3 3 3 0 Initiation control protein YabA LMBR1 PF04791.16 KIK50822.1 - 5.4 5.8 5.3 7.6 5.3 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KIK50822.1 - 8 6.6 10.2 9.3 6.4 4.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KIK50823.1 - 0.0076 16.4 1.4 0.012 15.8 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF5094 PF17015.5 KIK50823.1 - 0.032 14.4 0.5 0.047 13.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) GvpL_GvpF PF06386.11 KIK50823.1 - 0.079 12.9 1.7 0.12 12.3 1.7 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TMEM151 PF14857.6 KIK50823.1 - 0.091 11.7 0.3 0.1 11.5 0.3 1.0 1 0 0 1 1 1 0 TMEM151 family YabA PF06156.13 KIK50823.1 - 0.3 11.7 2.1 0.53 10.9 2.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF4404 PF14357.6 KIK50823.1 - 0.39 11.4 7.7 0.52 11.0 6.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) HALZ PF02183.18 KIK50823.1 - 3.8 7.8 9.7 1.1 9.5 1.5 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper ZapB PF06005.12 KIK50823.1 - 4.2 7.9 10.8 1.5 9.3 3.8 2.5 1 1 0 2 2 2 0 Cell division protein ZapB ATG16 PF08614.11 KIK50823.1 - 7.2 6.8 13.2 18 5.5 8.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) JmjC PF02373.22 KIK50826.1 - 6e-08 33.1 0.0 7.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIK50826.1 - 0.034 13.9 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain Cupin_2 PF07883.11 KIK50826.1 - 0.06 13.1 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Cupin domain Cupin_4 PF08007.12 KIK50826.1 - 0.072 12.5 0.0 0.072 12.5 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein Gti1_Pac2 PF09729.9 KIK50828.1 - 1.8e-44 152.0 1.0 1.8e-36 125.9 0.1 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Baculo_PEP_C PF04513.12 KIK50830.1 - 0.04 14.0 0.2 0.046 13.8 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BIV_Env PF05858.12 KIK50831.1 - 0.03 12.5 0.0 0.034 12.3 0.0 1.0 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF4710 PF15828.5 KIK50831.1 - 0.12 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Response_reg PF00072.24 KIK50831.1 - 0.18 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Response regulator receiver domain DUF4218 PF13960.6 KIK50832.1 - 0.0087 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF3080 PF11279.8 KIK50835.1 - 0.032 13.5 0.3 0.71 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) Aldedh PF00171.22 KIK50837.1 - 2.8e-08 32.7 0.0 2.9e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family APG12 PF04110.13 KIK50838.1 - 3.9e-10 40.0 0.0 4.1e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Aldedh PF00171.22 KIK50840.1 - 1.2e-52 178.9 0.0 1.5e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NIF PF03031.18 KIK50841.1 - 1.6e-14 53.9 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Retrotran_gag_3 PF14244.6 KIK50845.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AAA_16 PF13191.6 KIK50846.1 - 8.4e-06 26.3 0.0 1.1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK50846.1 - 1.7e-05 24.2 0.0 2.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_35 PF14516.6 KIK50846.1 - 0.027 13.3 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Roc PF08477.13 KIK50846.1 - 0.042 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 KIK50846.1 - 0.045 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF87 PF01935.17 KIK50846.1 - 0.085 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain DnaB_C PF03796.15 KIK50846.1 - 0.099 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 KIK50846.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 KIK50846.1 - 0.17 11.6 0.1 0.27 11.0 0.1 1.3 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KIK50846.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain RRM PF10378.9 KIK50847.1 - 0.11 12.2 4.5 1 9.1 0.1 2.9 2 1 1 3 3 3 0 Putative RRM domain NIF PF03031.18 KIK50849.1 - 9.1e-40 136.0 0.0 1.3e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sperm_Ag_HE2 PF05324.13 KIK50849.1 - 0.088 13.3 1.0 0.23 12.0 1.0 1.7 1 0 0 1 1 1 0 Sperm antigen HE2 adh_short PF00106.25 KIK50850.1 - 3e-23 82.3 0.0 6.1e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK50850.1 - 2.5e-14 53.4 0.0 1.3e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK50850.1 - 5.1e-08 33.0 0.0 8.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KIK50850.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KIK50850.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Herpes_IE68 PF02479.16 KIK50859.1 - 0.035 13.7 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein CxC4 PF18717.1 KIK50861.1 - 1.4e-47 160.8 0.1 3e-47 159.8 0.1 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK50862.1 - 0.0014 18.3 0.6 0.0015 18.2 0.6 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase NIF PF03031.18 KIK50863.1 - 1.6e-41 141.7 0.0 2.8e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.32 KIK50865.1 - 8e-118 381.0 18.4 7e-11 42.5 0.0 11.1 10 1 1 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50865.1 - 1.1e-36 125.0 4.4 0.0017 18.6 0.0 10.0 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50865.1 - 5.5e-18 65.6 0.2 0.0015 18.5 0.1 5.1 2 2 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50865.1 - 1.4e-17 63.6 2.7 0.48 9.0 0.0 8.3 7 2 0 8 8 8 8 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50865.1 - 3.3e-17 62.8 5.2 2.9 7.1 0.0 9.1 7 2 2 9 9 9 7 WD40-like domain PD40 PF07676.12 KIK50865.1 - 2.5e-13 49.6 0.0 43 4.2 0.0 10.5 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK50865.1 - 5.5e-12 45.4 14.4 5.1 7.1 0.0 10.2 11 0 0 11 11 11 2 Nitrous oxide reductase propeller repeat Ge1_WD40 PF16529.5 KIK50865.1 - 3e-11 42.9 1.6 8.1 5.3 0.0 9.1 1 1 9 10 10 10 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9_N PF02897.15 KIK50865.1 - 1.1e-06 27.8 3.7 3.2 6.5 0.0 7.0 2 2 7 9 9 9 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DsbC_N PF10411.9 KIK50865.1 - 1.9e-05 24.0 11.3 48 3.5 0.1 9.1 9 0 0 9 9 9 0 Disulfide bond isomerase protein N-terminus Imm17 PF15562.6 KIK50865.1 - 0.00016 21.5 0.0 1.1e+02 2.7 0.0 7.2 9 0 0 9 9 9 0 Immunity protein 17 COPI_C PF06957.11 KIK50865.1 - 0.00046 19.1 0.0 24 3.6 0.0 6.0 3 2 4 8 8 8 0 Coatomer (COPI) alpha subunit C-terminus Str_synth PF03088.16 KIK50865.1 - 0.00051 20.1 0.0 63 3.8 0.0 5.9 3 2 4 7 7 7 0 Strictosidine synthase Cuticle_4 PF15955.5 KIK50865.1 - 0.00097 19.8 2.4 1.1e+02 3.6 0.0 7.0 8 1 0 9 9 8 0 Cuticle protein DUF5122 PF17164.4 KIK50865.1 - 0.0011 19.2 6.0 77 3.7 0.0 7.6 9 0 0 9 9 8 0 Domain of unknown function (DUF5122) beta-propeller NHL PF01436.21 KIK50865.1 - 0.0018 18.2 14.9 31 4.9 0.0 8.7 11 0 0 11 11 10 0 NHL repeat Coatomer_WDAD PF04053.14 KIK50865.1 - 0.0064 15.6 3.1 0.15 11.1 0.5 3.4 1 1 1 3 3 3 1 Coatomer WD associated region LRR_10 PF18805.1 KIK50865.1 - 0.012 15.3 20.5 8.9 6.1 0.4 8.3 5 3 3 9 9 9 0 Leucine-rich repeat Frtz PF11768.8 KIK50865.1 - 0.012 13.9 0.0 51 2.0 0.0 5.2 1 1 2 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz Pectate_lyase_3 PF12708.7 KIK50865.1 - 0.044 13.6 20.5 4.5 7.0 0.5 7.5 2 2 6 8 8 8 0 Pectate lyase superfamily protein UNC-93 PF05978.16 KIK50865.1 - 0.18 11.5 7.4 1.1e+02 2.5 0.0 6.7 9 0 0 9 9 8 0 Ion channel regulatory protein UNC-93 Colicin_E5 PF12106.8 KIK50865.1 - 4.2 7.8 25.9 1.2e+02 3.1 0.1 8.9 9 1 1 10 10 10 0 Colicin E5 ribonuclease domain SSP160 PF06933.11 KIK50867.1 - 0.95 7.6 6.1 1.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DNA_pol_phi PF04931.13 KIK50867.1 - 1.2 7.2 5.6 1.5 6.8 5.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KIK50867.1 - 6.3 6.5 8.3 9.1 5.9 8.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SSP160 PF06933.11 KIK50871.1 - 0.36 9.0 4.8 0.38 8.9 4.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.32 KIK50872.1 - 1.6e-111 361.0 32.5 1.3e-10 41.7 0.0 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50872.1 - 3.3e-35 120.2 9.4 0.019 15.2 0.0 11.0 1 1 10 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50872.1 - 9.8e-21 74.5 1.8 7.5e-05 22.7 0.1 4.3 2 2 0 4 4 4 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK50872.1 - 1.2e-15 57.7 3.7 1.1 8.5 0.0 9.7 9 2 2 11 11 11 4 WD40-like domain Ge1_WD40 PF16529.5 KIK50872.1 - 2.3e-13 49.8 2.2 0.61 9.0 0.0 9.2 2 2 5 9 9 9 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK50872.1 - 3.8e-13 49.0 0.3 10 6.2 0.0 10.4 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK50872.1 - 1.4e-12 47.0 18.0 0.12 11.0 0.1 8.7 5 4 3 9 9 9 5 Nucleoporin Nup120/160 nos_propeller PF18764.1 KIK50872.1 - 2.5e-12 46.5 13.2 2 8.4 0.0 9.1 9 0 0 9 9 9 3 Nitrous oxide reductase propeller repeat SdiA-regulated PF06977.11 KIK50872.1 - 5e-07 29.2 0.0 0.37 10.0 0.0 4.5 1 1 5 6 6 6 3 SdiA-regulated DUF5018 PF16410.5 KIK50872.1 - 5.3e-05 22.1 1.2 1.1 7.9 0.0 4.8 1 1 5 6 6 6 1 Domain of unknown function (DUF5018) potato_inhibit PF00280.18 KIK50872.1 - 7.2e-05 23.4 10.8 6.5 7.5 0.0 8.1 5 2 4 9 9 9 1 Potato inhibitor I family DsbC_N PF10411.9 KIK50872.1 - 7.5e-05 22.1 9.2 67 3.1 0.0 8.5 9 0 0 9 9 9 0 Disulfide bond isomerase protein N-terminus Peptidase_S9_N PF02897.15 KIK50872.1 - 9.7e-05 21.3 4.6 8.6 5.0 0.0 6.4 1 1 3 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain LRR_10 PF18805.1 KIK50872.1 - 0.001 18.7 27.1 14 5.4 0.2 9.9 6 3 5 11 11 11 0 Leucine-rich repeat COPI_C PF06957.11 KIK50872.1 - 0.0025 16.7 0.0 65 2.1 0.0 6.0 4 2 4 9 9 9 0 Coatomer (COPI) alpha subunit C-terminus NHL PF01436.21 KIK50872.1 - 0.0031 17.4 15.4 89 3.4 0.0 9.3 10 0 0 10 10 10 0 NHL repeat DUF5122 PF17164.4 KIK50872.1 - 0.0044 17.3 11.6 1e+02 3.3 0.0 8.4 10 0 0 10 10 10 0 Domain of unknown function (DUF5122) beta-propeller AHJR-like PF18743.1 KIK50872.1 - 0.016 14.8 0.1 64 3.1 0.0 4.3 3 2 2 5 5 5 0 REase_AHJR-like Imm17 PF15562.6 KIK50872.1 - 0.031 14.1 0.0 2.1e+02 1.9 0.0 5.7 8 0 0 8 8 7 0 Immunity protein 17 PQQ_3 PF13570.6 KIK50872.1 - 1.2 9.7 33.5 14 6.3 0.5 8.8 5 3 5 10 10 10 0 PQQ-like domain Colicin_E5 PF12106.8 KIK50872.1 - 6.1 7.2 23.4 4.2 7.8 0.2 7.9 5 2 2 9 9 9 0 Colicin E5 ribonuclease domain HTH_23 PF13384.6 KIK50873.1 - 5.4e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KIK50873.1 - 4.3e-06 26.7 0.0 7.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.6 KIK50873.1 - 3.5e-05 23.6 0.0 5.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 KIK50873.1 - 0.00028 21.0 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.18 KIK50873.1 - 0.00077 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_7 PF02796.15 KIK50873.1 - 0.00085 19.4 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 KIK50873.1 - 0.0032 17.7 0.0 0.0052 17.1 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.7 KIK50873.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KIK50873.1 - 0.17 12.5 0.0 0.64 10.7 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain PRP9_N PF16958.5 KIK50873.1 - 0.24 11.4 0.0 0.37 10.8 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus WD40 PF00400.32 KIK50875.1 - 6e-134 432.0 26.9 4e-11 43.3 0.2 13.2 12 1 1 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50875.1 - 1e-38 131.5 10.1 0.018 15.3 0.0 12.0 2 2 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50875.1 - 2.2e-25 89.7 1.2 0.00027 20.9 0.0 6.0 1 1 5 7 7 7 7 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50875.1 - 4.8e-20 71.7 15.9 0.29 9.7 0.0 11.6 5 4 4 12 12 12 9 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50875.1 - 8.6e-19 68.0 8.4 2.7 7.2 0.1 11.7 9 3 3 12 12 12 5 WD40-like domain PD40 PF07676.12 KIK50875.1 - 4.8e-15 55.0 0.0 24 5.0 0.0 11.9 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK50875.1 - 8.4e-15 54.5 5.9 4.6 6.1 0.0 11.4 1 1 11 12 12 12 3 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK50875.1 - 5.3e-13 48.7 18.3 3.3 7.7 0.1 11.1 12 0 0 12 12 12 2 Nitrous oxide reductase propeller repeat DsbC_N PF10411.9 KIK50875.1 - 2.4e-06 26.9 16.4 58 3.2 0.0 11.1 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus COPI_C PF06957.11 KIK50875.1 - 4.1e-06 25.8 0.0 11 4.7 0.0 6.8 4 2 3 7 7 7 0 Coatomer (COPI) alpha subunit C-terminus NHL PF01436.21 KIK50875.1 - 9.9e-06 25.3 17.5 8.5 6.6 0.0 10.3 12 0 0 12 12 11 1 NHL repeat Peptidase_S9_N PF02897.15 KIK50875.1 - 0.00016 20.6 4.8 4.1 6.1 0.1 6.8 3 3 2 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain LRR_10 PF18805.1 KIK50875.1 - 0.0048 16.5 21.4 20 5.0 0.0 9.4 11 1 1 12 12 12 0 Leucine-rich repeat DUF5122 PF17164.4 KIK50875.1 - 0.0072 16.6 16.8 75 3.7 0.0 9.3 11 0 0 11 11 11 0 Domain of unknown function (DUF5122) beta-propeller AsnC_trans_reg PF01037.21 KIK50875.1 - 0.17 11.9 4.8 1.3e+02 2.7 0.0 6.6 9 0 0 9 9 8 0 Lrp/AsnC ligand binding domain PQQ_3 PF13570.6 KIK50875.1 - 0.17 12.4 42.1 2.7 8.6 0.1 10.9 4 4 8 12 12 12 0 PQQ-like domain DUF4279 PF14106.6 KIK50875.1 - 0.2 11.9 0.3 4.5e+02 1.0 0.0 5.4 3 2 3 6 6 6 0 Domain of unknown function (DUF4279) Big_4 PF07532.11 KIK50875.1 - 1.1 9.0 28.2 9 6.1 0.1 10.5 11 0 0 11 11 11 0 Bacterial Ig-like domain (group 4) Phage_sheath_1 PF04984.14 KIK50875.1 - 9.5 6.0 13.7 56 3.5 0.0 7.0 11 0 0 11 11 11 0 Phage tail sheath protein subtilisin-like domain DsrD PF08679.11 KIK50876.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) DUF4018 PF13210.6 KIK50876.1 - 0.082 12.7 0.3 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) KDZ PF18758.1 KIK50878.1 - 5.1e-11 42.6 0.1 6.7e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Ribosomal_L27_C PF18471.1 KIK50878.1 - 0.074 12.5 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain Phytoreo_S7 PF07236.11 KIK50883.1 - 0.12 10.7 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein WD40 PF00400.32 KIK50884.1 - 2.3e-07 31.4 0.3 6.9e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50884.1 - 0.048 14.0 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50884.1 - 0.27 10.5 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 WD40-like domain WD40 PF00400.32 KIK50890.1 - 8.7e-147 472.6 48.0 2e-10 41.1 0.2 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50890.1 - 1e-42 144.3 14.5 0.0051 17.1 0.1 14.2 1 1 13 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50890.1 - 1.6e-23 83.6 2.2 0.00016 21.6 0.0 6.5 1 1 8 9 9 9 8 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK50890.1 - 3.2e-13 49.7 10.0 1.4 8.2 0.0 12.4 13 1 1 14 14 14 3 WD40-like domain Nup160 PF11715.8 KIK50890.1 - 7.9e-13 47.9 14.8 0.32 9.6 0.0 10.5 3 1 9 13 13 13 5 Nucleoporin Nup120/160 PD40 PF07676.12 KIK50890.1 - 6e-11 42.0 0.0 37 4.4 0.0 10.9 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat COPI_C PF06957.11 KIK50890.1 - 1.4e-07 30.6 0.0 1 8.0 0.0 7.2 5 3 4 9 9 9 1 Coatomer (COPI) alpha subunit C-terminus nos_propeller PF18764.1 KIK50890.1 - 8.8e-06 25.5 31.8 12 5.9 0.0 12.2 13 1 1 14 14 14 0 Nitrous oxide reductase propeller repeat NHL PF01436.21 KIK50890.1 - 7.8e-05 22.5 18.2 38 4.6 0.1 10.8 12 0 0 12 12 12 0 NHL repeat AsnC_trans_reg PF01037.21 KIK50890.1 - 0.00044 20.2 0.9 3e+02 1.5 0.0 8.3 11 0 0 11 11 11 0 Lrp/AsnC ligand binding domain Nucleoporin_N PF08801.11 KIK50890.1 - 0.009 14.8 11.8 0.022 13.5 0.7 5.9 2 1 5 7 7 7 1 Nup133 N terminal like LRR_10 PF18805.1 KIK50890.1 - 0.024 14.3 20.6 70 3.2 0.0 10.3 9 3 2 12 12 12 0 Leucine-rich repeat Phytase-like PF13449.6 KIK50890.1 - 0.026 14.4 0.0 14 5.6 0.0 3.1 2 1 0 2 2 2 0 Esterase-like activity of phytase DsbC_N PF10411.9 KIK50890.1 - 0.6 9.6 18.1 2.3e+02 1.3 0.0 10.1 14 0 0 14 14 14 0 Disulfide bond isomerase protein N-terminus DHFR_2 PF06442.11 KIK50890.1 - 9.1 6.2 13.5 1.2 9.1 0.1 5.2 5 1 1 6 6 5 0 R67 dihydrofolate reductase WD40 PF00400.32 KIK50893.1 - 1.8e-123 398.8 35.9 6.3e-11 42.7 0.2 12.6 11 1 1 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50893.1 - 6.5e-35 119.3 11.1 0.014 15.6 0.0 11.6 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50893.1 - 1e-17 64.7 5.4 0.0015 18.4 0.1 6.3 1 1 0 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK50893.1 - 3.4e-17 62.7 1.8 0.54 9.5 0.0 8.8 8 2 2 10 10 10 5 WD40-like domain Ge1_WD40 PF16529.5 KIK50893.1 - 4.3e-16 58.8 6.9 2.4 7.0 0.0 10.7 1 1 10 11 11 11 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK50893.1 - 8.6e-12 44.5 15.0 1.3 7.6 0.1 9.2 3 2 5 9 9 9 6 Nucleoporin Nup120/160 PD40 PF07676.12 KIK50893.1 - 6.2e-11 41.9 0.9 23 5.1 0.0 11.2 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK50893.1 - 6.3e-09 35.6 11.5 6.1 6.8 0.0 9.7 10 1 1 11 11 10 1 Nitrous oxide reductase propeller repeat Pectate_lyase_3 PF12708.7 KIK50893.1 - 0.00044 20.2 10.4 0.19 11.5 0.2 5.7 3 2 3 6 6 6 2 Pectate lyase superfamily protein RAB3GAP2_N PF14655.6 KIK50893.1 - 0.0013 18.1 0.0 0.48 9.6 0.0 4.2 5 1 1 6 6 6 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DsbC_N PF10411.9 KIK50893.1 - 0.014 14.8 7.1 1.7e+02 1.7 0.0 7.8 10 0 0 10 10 10 0 Disulfide bond isomerase protein N-terminus Lipase_2 PF01674.18 KIK50893.1 - 0.041 13.4 0.1 35 3.8 0.0 4.4 2 2 1 3 3 3 0 Lipase (class 2) DUF5122 PF17164.4 KIK50893.1 - 0.075 13.3 14.7 31 5.0 0.0 8.0 10 0 0 10 10 9 0 Domain of unknown function (DUF5122) beta-propeller DUF3748 PF12566.8 KIK50893.1 - 0.35 10.8 3.4 16 5.5 0.0 4.9 5 2 1 7 7 7 0 Protein of unknown function (DUF3748) PQQ_3 PF13570.6 KIK50893.1 - 0.66 10.5 25.6 3 8.4 0.0 8.6 3 3 7 10 10 10 0 PQQ-like domain LRR_10 PF18805.1 KIK50893.1 - 1.4 8.6 24.7 53 3.6 0.1 9.3 6 2 3 10 10 10 0 Leucine-rich repeat NHL PF01436.21 KIK50893.1 - 1.9 8.7 18.3 1.4e+02 2.8 0.0 8.7 12 0 0 12 12 10 0 NHL repeat ATP-synt_G PF04718.15 KIK50894.1 - 3.8e-17 63.0 2.8 9.5e-17 61.7 0.2 2.1 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit SPT6_acidic PF14632.6 KIK50896.1 - 0.58 10.8 10.4 2.3 8.9 0.5 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 RSN1_TM PF13967.6 KIK50897.1 - 0.0089 15.8 1.2 0.012 15.3 0.9 1.2 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport GPI2 PF06432.11 KIK50898.1 - 0.036 13.5 3.9 0.047 13.1 3.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase SPC25 PF06703.11 KIK50898.1 - 0.26 11.1 1.0 2.9 7.6 0.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Mem_trans PF03547.18 KIK50899.1 - 3.8e-12 45.3 11.3 9.6e-10 37.4 0.3 2.3 2 1 0 2 2 2 2 Membrane transport protein TMEM220 PF15071.6 KIK50899.1 - 0.015 16.1 1.0 1 10.1 0.4 2.8 2 0 0 2 2 2 0 Transmembrane family 220, helix Metallophos PF00149.28 KIK50900.1 - 1.6e-12 48.3 3.3 4.5e-12 46.9 2.8 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK50900.1 - 3.1e-05 24.2 0.0 0.0014 18.8 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 KIK50902.1 - 7.8e-18 64.5 0.1 2.6e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50902.1 - 7.3e-06 26.2 0.0 0.026 14.8 0.0 2.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK50902.1 - 0.02 14.2 0.0 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 KIK50902.1 - 0.051 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50902.1 - 0.052 12.2 0.0 2.1 6.9 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Mg_trans_NIPA PF05653.14 KIK50908.1 - 3.6e-21 75.5 12.0 4.4e-20 72.0 12.0 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF2254 PF10011.9 KIK50908.1 - 5.3 5.8 6.6 0.31 9.8 0.2 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) DUF5362 PF17319.2 KIK50911.1 - 0.054 13.3 0.1 0.079 12.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) AAA_16 PF13191.6 KIK50915.1 - 0.00043 20.7 0.0 0.00053 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK50915.1 - 0.0056 16.6 0.3 0.019 14.9 0.3 1.8 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 KIK50915.1 - 0.014 15.6 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK50915.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK50915.1 - 0.02 14.8 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 KIK50915.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KIK50915.1 - 0.03 13.5 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KIK50915.1 - 0.046 13.6 0.0 0.076 12.9 0.0 1.5 1 1 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 KIK50915.1 - 0.066 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK50915.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KIK50915.1 - 0.072 13.5 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIK50915.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HHH_7 PF14635.6 KIK50915.1 - 0.19 12.1 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_18 PF13238.6 KIK50915.1 - 0.43 11.1 1.6 0.62 10.6 1.6 1.6 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK50916.1 - 1e-07 32.5 2.6 1.1e-07 32.4 0.7 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50916.1 - 0.0072 16.6 0.0 0.0096 16.2 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK50916.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mg_trans_NIPA PF05653.14 KIK50918.1 - 1.3e-26 93.4 14.9 8.1e-26 90.8 14.9 1.8 1 1 0 1 1 1 1 Magnesium transporter NIPA Neurensin PF14927.6 KIK50918.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.4 2 2 1 3 3 3 0 Neurensin DUF2254 PF10011.9 KIK50918.1 - 1.7 7.4 8.2 0.054 12.3 1.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF2070 PF09843.9 KIK50918.1 - 2 6.6 13.7 2.4 6.4 13.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1772 PF08592.11 KIK50918.1 - 3.6 7.9 10.6 2.4 8.4 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Aldo_ket_red PF00248.21 KIK50919.1 - 2.5e-07 30.2 0.0 3.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KIK50921.1 - 0.0073 17.1 0.0 3.9 8.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat MmgE_PrpD PF03972.14 KIK50923.1 - 0.12 10.9 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family NPL PF17800.1 KIK50925.1 - 0.093 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin-like domain Na_H_antiport_1 PF06965.12 KIK50929.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter 1 NACHT PF05729.12 KIK50930.1 - 4.3e-11 43.0 0.0 6.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK50930.1 - 0.048 13.9 0.0 0.29 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK50930.1 - 0.059 13.4 0.0 3.9 7.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain Ank_4 PF13637.6 KIK50931.1 - 2.9e-25 88.3 6.2 3.5e-08 33.8 0.7 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK50931.1 - 2e-21 76.3 13.1 3.5e-11 43.5 3.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK50931.1 - 3.8e-18 63.7 11.5 0.029 14.9 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KIK50931.1 - 1.2e-17 63.5 21.3 0.0093 16.4 0.4 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KIK50931.1 - 4.8e-08 33.1 10.7 0.0032 17.7 0.7 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 KIK50931.1 - 0.00042 20.2 0.1 0.26 11.3 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Globin PF00042.22 KIK50931.1 - 0.031 14.9 5.7 17 6.0 0.1 4.2 1 1 4 5 5 5 0 Globin NdhO PF11910.8 KIK50931.1 - 0.13 12.5 0.4 17 5.7 0.1 3.7 3 2 1 4 4 4 0 Cyanobacterial and plant NDH-1 subunit O YajC PF02699.15 KIK50931.1 - 0.14 12.0 2.7 44 4.1 0.0 3.9 2 1 2 4 4 4 0 Preprotein translocase subunit DUF1353 PF07087.11 KIK50931.1 - 0.16 11.7 0.3 16 5.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1353) Toprim_3 PF13362.6 KIK50931.1 - 0.17 12.3 3.3 1 9.8 2.4 2.4 2 1 0 2 2 2 0 Toprim domain Pns11_12 PF17464.2 KIK50931.1 - 0.78 9.4 2.5 14 5.3 0.2 2.6 2 1 1 3 3 3 0 Non-structural protein 11 and 12 PorB PF11565.8 KIK50931.1 - 1.1 9.7 8.1 17 5.9 0.1 3.6 1 1 2 4 4 4 0 Alpha helical Porin B DUF1843 PF08898.10 KIK50931.1 - 1.6 9.3 11.4 5.3 7.6 1.1 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) Retrotrans_gag PF03732.17 KIK50932.1 - 0.00031 20.9 0.4 0.0041 17.4 0.0 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein RabGAP-TBC PF00566.18 KIK50934.1 - 2e-45 155.1 0.0 3e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KIK50934.1 - 1.6e-05 25.3 0.3 0.0013 19.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair GRAM PF02893.20 KIK50934.1 - 1.8e-05 24.6 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KIK50934.1 - 8.8e-05 22.1 2.0 0.0012 18.6 0.4 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KIK50934.1 - 0.00035 19.9 0.5 0.0014 18.1 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KIK50934.1 - 0.064 12.8 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KIK50934.1 - 0.13 12.2 1.1 8 6.4 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair UPF0669 PF17065.5 KIK50934.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Pes-10 PF07149.11 KIK50934.1 - 8.5 5.3 5.3 13 4.7 5.3 1.2 1 0 0 1 1 1 0 Pes-10 WD40 PF00400.32 KIK50935.1 - 4.7e-54 179.1 30.1 3.5e-08 34.0 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK50935.1 - 4.4e-19 68.6 5.1 0.00034 20.9 0.1 5.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK50935.1 - 1e-11 45.1 0.3 3.3e-06 27.1 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK50935.1 - 5.3e-08 32.0 6.5 0.014 14.1 0.1 4.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK50935.1 - 4.8e-06 26.1 0.3 0.025 13.9 0.0 2.8 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KIK50935.1 - 0.00011 21.4 8.2 0.61 9.0 0.0 4.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 KIK50935.1 - 0.011 15.3 1.1 0.032 13.8 1.1 1.8 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain Utp8 PF10395.9 KIK50935.1 - 0.011 14.2 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 Utp8 family IKI3 PF04762.12 KIK50935.1 - 0.33 8.9 2.9 5.2 4.9 0.2 2.6 2 2 1 3 3 3 0 IKI3 family PRIMA1 PF16101.5 KIK50935.1 - 5.5 7.0 8.4 12 6.0 8.4 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 F-box-like PF12937.7 KIK50937.1 - 2.3e-05 24.2 0.6 5.2e-05 23.1 0.6 1.7 1 1 0 1 1 1 1 F-box-like HSM3_N PF18795.1 KIK50937.1 - 0.11 11.9 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, N terminal domain DUF489 PF04356.12 KIK50937.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF489) DUF5448 PF17526.2 KIK50938.1 - 0.096 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5448) DUF4453 PF14627.6 KIK50938.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Cep57_MT_bd PF06657.13 KIK50940.1 - 0.074 13.5 0.4 0.22 12.0 0.4 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Integrase_H2C2 PF17921.1 KIK50943.1 - 1.2e-10 41.3 1.3 1.7e-10 40.9 1.3 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 KIK50945.1 - 0.0043 17.3 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Dehydratase_hem PF13816.6 KIK50945.1 - 0.02 14.3 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase DUF4692 PF15763.5 KIK50946.1 - 0.032 14.7 0.8 0.032 14.7 0.8 3.7 1 1 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Choline_kinase PF01633.20 KIK50948.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIK50948.1 - 0.0025 17.8 0.0 0.068 13.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK50948.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KIK50948.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 KIK50948.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ParA PF10609.9 KIK50949.1 - 2.8e-61 207.1 0.0 1.2e-60 205.0 0.0 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK50949.1 - 3.8e-09 36.7 0.0 1.9e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK50949.1 - 5.9e-06 25.7 0.5 0.031 13.5 0.1 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 KIK50949.1 - 5.8e-05 23.1 0.5 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KIK50949.1 - 0.00053 19.4 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ DUF1326 PF07040.11 KIK50951.1 - 0.046 13.7 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) DDE_1 PF03184.19 KIK50955.1 - 2.8e-14 53.2 0.3 3.9e-14 52.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease p450 PF00067.22 KIK50956.1 - 1.4e-24 86.7 0.0 1.4e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK50957.1 - 7.2e-64 216.2 0.0 8.7e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Macoilin PF09726.9 KIK50964.1 - 1.5 7.3 5.5 1.8 7.0 5.5 1.2 1 0 0 1 1 1 0 Macoilin family Tyrosinase PF00264.20 KIK50965.1 - 5.4e-43 147.8 0.1 1.9e-42 146.1 0.1 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIK50965.1 - 1.8e-06 28.6 0.0 3.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain UPF0060 PF02694.15 KIK50967.1 - 0.046 13.9 0.5 0.082 13.1 0.2 1.5 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Acetyltransf_10 PF13673.7 KIK50968.1 - 0.00023 21.1 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK50968.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Zn_clus PF00172.18 KIK50969.1 - 0.00016 21.7 6.1 0.16 12.2 0.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 KIK50969.1 - 0.79 7.9 4.2 0.8 7.9 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CDV3 PF15359.6 KIK50969.1 - 1 9.8 7.5 0.89 10.0 5.1 2.2 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Ammonium_transp PF00909.21 KIK50972.1 - 3.6e-113 378.3 29.7 4.2e-113 378.1 29.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pirin PF02678.16 KIK50972.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Pirin GN3L_Grn1 PF08701.11 KIK50975.1 - 0.11 12.7 0.5 12 6.1 0.0 3.5 2 1 2 4 4 4 0 GNL3L/Grn1 putative GTPase zf-CCHH PF10283.9 KIK50980.1 - 0.16 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 PBZ domain SNF2_N PF00176.23 KIK50982.1 - 6.9e-58 196.0 0.2 1.4e-57 195.0 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK50982.1 - 9e-21 74.3 0.0 1.2e-18 67.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK50982.1 - 4.3e-05 23.6 0.0 8.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK50982.1 - 0.00031 20.5 0.0 0.00075 19.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 KIK50982.1 - 0.0013 18.6 17.3 0.019 14.9 10.6 2.7 2 1 1 3 3 3 2 PHD-finger Zf_RING PF16744.5 KIK50982.1 - 0.019 15.1 15.6 0.58 10.3 7.7 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 KIK50982.1 - 0.037 14.4 0.7 0.037 14.4 0.7 2.6 2 0 0 2 2 2 0 C1 domain HDA2-3 PF11496.8 KIK50982.1 - 0.039 13.1 2.7 0.046 12.9 0.1 2.3 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-MYND PF01753.18 KIK50983.1 - 1.8e-10 40.8 26.3 1.4e-08 34.7 13.1 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 KIK50983.1 - 0.00011 22.2 8.5 0.017 15.2 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 GCV_T PF01571.21 KIK50984.1 - 9.9e-19 67.7 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain FAS_meander PF17951.1 KIK50984.1 - 1e-10 41.6 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain DUF4218 PF13960.6 KIK50987.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) 2OG-FeII_Oxy_3 PF13640.6 KIK50988.1 - 0.0057 17.5 0.1 0.17 12.8 0.1 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.7 KIK50988.1 - 0.048 13.0 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily PaO PF08417.12 KIK50988.1 - 0.085 13.0 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Pheophorbide a oxygenase zf-Mss51 PF13824.6 KIK50989.1 - 0.022 14.8 1.1 0.022 14.8 1.1 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KIK50990.1 - 0.012 15.7 20.8 0.015 15.4 1.7 3.9 4 0 0 4 4 4 0 MYND finger M-factor PF03855.13 KIK50990.1 - 0.042 14.0 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 M-factor zf-Mss51 PF13824.6 KIK50990.1 - 0.23 11.6 9.7 0.31 11.2 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_4 PF14570.6 KIK50990.1 - 0.63 9.9 6.9 0.9 9.4 1.5 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain OPT PF03169.15 KIK50991.1 - 6.7e-150 500.7 45.1 7.6e-150 500.5 45.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 KIK50993.1 - 9.4e-73 244.8 0.1 9.4e-73 244.8 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK50993.1 - 5.7e-51 173.3 0.1 5.7e-51 173.3 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KIK50993.1 - 7.3e-23 80.7 0.0 1.6e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 KIK50993.1 - 1.9e-09 37.9 0.4 4.8e-09 36.7 0.4 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KIK50993.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK50993.1 - 6.4e-05 22.1 0.4 0.0001 21.4 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK50993.1 - 7.4e-05 21.7 0.0 7.4e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIK50993.1 - 0.01 15.7 0.1 0.01 15.7 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family VIR_N PF15912.5 KIK50993.1 - 0.49 9.9 17.7 0.024 14.3 10.7 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal RicinB_lectin_2 PF14200.6 KIK50997.1 - 0.021 15.5 0.0 0.25 12.1 0.0 2.3 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Kelch_6 PF13964.6 KIK50997.1 - 0.039 14.2 0.2 0.084 13.2 0.2 1.6 1 0 0 1 1 1 0 Kelch motif Glyco_hydro_28 PF00295.17 KIK50998.1 - 1.9e-36 125.8 4.5 3.1e-36 125.1 4.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIK50998.1 - 0.17 11.7 22.3 0.71 9.7 21.6 2.3 1 1 0 1 1 1 0 Right handed beta helix region DUF563 PF04577.14 KIK51000.1 - 1.7e-18 67.6 0.1 5.7e-18 65.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) WD40 PF00400.32 KIK51001.1 - 1.1e-35 121.0 24.6 2.4e-10 40.8 0.8 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51001.1 - 5.8e-10 39.3 0.4 0.03 14.6 0.0 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK51001.1 - 0.00049 19.9 5.9 2.4 8.2 0.0 5.0 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK51001.1 - 0.011 14.7 2.3 52 2.6 0.0 4.5 1 1 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK51001.1 - 0.044 13.1 0.0 9.2 5.5 0.0 3.0 1 1 1 3 3 3 0 WD40-like domain Me-amine-dh_H PF06433.11 KIK51001.1 - 0.088 11.7 0.0 1.2 8.0 0.0 2.1 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) PDE8 PF08629.10 KIK51002.1 - 0.032 14.2 1.6 7.8 6.6 0.0 3.8 1 1 3 4 4 4 0 PDE8 phosphodiesterase DUF3262 PF11660.8 KIK51003.1 - 0.095 13.1 0.7 0.095 13.1 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Asp PF00026.23 KIK51004.1 - 5.5e-51 173.9 1.2 6.9e-51 173.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIK51004.1 - 2.8e-06 27.9 4.0 0.017 15.8 0.8 3.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 KIK51004.1 - 6.2e-06 26.6 0.5 8.5e-05 22.9 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KIK51004.1 - 6.7e-06 26.6 0.7 0.008 16.7 0.0 3.6 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KIK51004.1 - 0.049 13.4 0.1 0.73 9.6 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal p450 PF00067.22 KIK51005.1 - 1.8e-46 158.9 0.0 2.5e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cytokin_check_N PF10407.9 KIK51005.1 - 0.068 13.1 0.0 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus p450 PF00067.22 KIK51006.1 - 1.6e-44 152.4 0.0 2e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reo_sigmaC PF04582.12 KIK51006.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain DUF4232 PF14016.6 KIK51014.1 - 0.016 15.4 0.2 0.018 15.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) B1 PF02246.15 KIK51014.1 - 0.057 13.5 0.9 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein L b1 domain NACHT PF05729.12 KIK51018.1 - 0.00039 20.4 0.1 0.0011 19.0 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK51018.1 - 0.0011 19.3 0.0 0.0014 19.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.17 KIK51018.1 - 0.0086 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK51018.1 - 0.0099 16.3 0.1 0.023 15.1 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 KIK51018.1 - 0.011 15.9 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK51018.1 - 0.018 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIK51018.1 - 0.025 15.0 0.1 0.034 14.6 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIK51018.1 - 0.033 13.4 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ComR_TPR PF18710.1 KIK51018.1 - 0.035 13.7 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 ComR tetratricopeptide AAA_7 PF12775.7 KIK51018.1 - 0.042 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region APS_kinase PF01583.20 KIK51018.1 - 0.054 13.4 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KIK51018.1 - 0.058 14.0 0.2 0.062 13.9 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK51018.1 - 0.076 12.7 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK51018.1 - 0.078 12.1 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KIK51018.1 - 0.12 12.6 0.0 0.17 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK51018.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK51018.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase WD40 PF00400.32 KIK51019.1 - 1.3e-24 86.0 17.2 1.3e-09 38.5 0.8 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51019.1 - 2.6e-09 37.3 0.0 0.016 15.5 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK51019.1 - 6.2e-07 29.2 1.7 0.13 12.3 0.1 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK51019.1 - 2.6e-05 23.4 0.1 0.73 8.7 0.0 3.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK51019.1 - 0.00057 19.7 0.9 0.026 14.3 0.9 2.5 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK51019.1 - 0.0067 15.1 0.7 0.71 8.4 0.0 2.7 2 1 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK51019.1 - 0.01 15.2 0.0 22 4.3 0.0 2.9 2 1 1 3 3 3 0 WD40-like domain WD40_3 PF15911.5 KIK51019.1 - 0.02 14.9 0.8 1.9 8.6 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ PF01011.21 KIK51019.1 - 0.061 13.3 0.1 19 5.4 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK51019.1 - 0.075 11.8 0.1 7.9 5.2 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40 PF00400.32 KIK51021.1 - 9.5e-20 70.6 3.4 1.3e-09 38.5 0.8 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51021.1 - 1.1e-06 28.9 0.1 0.0084 16.4 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51021.1 - 2.4e-05 23.5 0.2 0.074 12.0 0.1 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51021.1 - 0.0029 17.5 0.3 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF4072 PF13284.6 KIK51021.1 - 0.003 18.0 0.0 9.7 6.7 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4072) DUF4784 PF16023.5 KIK51021.1 - 0.021 13.8 0.0 0.42 9.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4784) ETX_MTX2 PF03318.13 KIK51023.1 - 3.8e-08 33.4 6.5 5.5e-08 32.9 6.5 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Jacalin PF01419.17 KIK51023.1 - 2.3e-07 30.8 0.0 1.1e-05 25.4 0.0 2.7 2 1 0 2 2 2 1 Jacalin-like lectin domain PUA_3 PF17785.1 KIK51023.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 PUA-like domain MG3 PF17791.1 KIK51023.1 - 0.12 12.7 0.2 0.31 11.3 0.1 1.8 1 1 0 1 1 1 0 Macroglobulin domain MG3 NACHT PF05729.12 KIK51026.1 - 1.5e-05 24.9 0.9 0.00015 21.8 0.9 2.4 1 1 0 1 1 1 1 NACHT domain NepR PF18557.1 KIK51026.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma factor NepR DUF746 PF05344.11 KIK51026.1 - 0.15 11.9 0.0 0.63 9.9 0.0 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF4404 PF14357.6 KIK51026.1 - 0.3 11.8 6.3 0.42 11.3 3.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3347 PF11827.8 KIK51026.1 - 0.45 10.7 3.2 1.1 9.4 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PIN_8 PF18476.1 KIK51026.1 - 2.5 7.9 10.0 0.2 11.5 4.5 1.9 2 1 0 2 2 2 0 PIN like domain Goodbye PF17109.5 KIK51026.1 - 4.1 7.9 5.4 14 6.2 0.1 3.5 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain WD40 PF00400.32 KIK51027.1 - 7.2e-93 302.0 58.3 2.2e-10 41.0 0.5 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51027.1 - 3.4e-40 136.2 0.1 0.0058 16.9 0.0 9.9 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51027.1 - 2e-25 89.5 6.1 0.076 12.0 0.0 10.0 3 2 6 10 10 10 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51027.1 - 7.2e-23 80.0 11.9 0.048 13.6 0.1 10.9 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK51027.1 - 1.1e-11 44.2 7.3 2.7 6.5 0.0 9.2 9 1 1 10 10 10 3 Nucleoporin Nup120/160 PQQ PF01011.21 KIK51027.1 - 7e-09 35.2 6.5 1.3 9.1 0.1 8.6 9 0 0 9 9 9 2 PQQ enzyme repeat ATP-sulfurylase PF01747.17 KIK51027.1 - 4.7e-08 32.8 0.0 9 5.7 0.0 7.4 9 0 0 9 9 9 2 ATP-sulfurylase DPPIV_N PF00930.21 KIK51027.1 - 1.2e-06 27.5 0.1 4 6.1 0.0 6.6 2 1 5 7 7 7 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_like PF17005.5 KIK51027.1 - 3.2e-06 26.7 0.1 16 4.7 0.0 6.6 5 2 3 8 8 8 0 WD40-like domain Nbas_N PF15492.6 KIK51027.1 - 5e-06 26.0 9.7 7.2 5.9 0.0 8.4 4 3 5 9 9 9 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK51027.1 - 8.3e-06 24.4 0.0 6.4 5.0 0.0 5.3 2 2 4 6 6 6 3 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK51027.1 - 2.2e-05 23.5 2.0 0.049 12.4 0.1 4.5 1 1 3 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Methyltransf_10 PF05971.12 KIK51027.1 - 0.00016 21.1 0.9 0.33 10.3 0.1 3.3 3 0 0 3 3 3 1 RNA methyltransferase WD40_3 PF15911.5 KIK51027.1 - 0.00036 20.5 11.1 11 6.1 0.0 8.1 9 0 0 9 9 9 0 WD domain, G-beta repeat Cuticle_4 PF15955.5 KIK51027.1 - 0.0033 18.1 6.4 54 4.6 0.0 6.8 9 0 0 9 9 7 0 Cuticle protein PQQ_2 PF13360.6 KIK51027.1 - 0.0034 17.0 19.7 2.3 7.7 3.6 5.7 1 1 3 4 4 4 2 PQQ-like domain BAT PF15915.5 KIK51027.1 - 0.24 11.3 8.8 9.1 6.1 0.5 5.0 3 2 3 7 7 7 0 GAF and HTH_10 associated domain WD40 PF00400.32 KIK51028.1 - 8.1e-30 102.4 27.8 2e-06 28.4 0.6 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51028.1 - 2e-12 47.2 0.4 0.01 16.1 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51028.1 - 9.3e-07 28.1 1.2 0.055 12.4 0.1 3.9 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51028.1 - 5.2e-06 26.2 5.0 3.1 7.9 0.0 5.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat ATP-sulfurylase PF01747.17 KIK51028.1 - 2.2e-05 24.0 0.3 2.2 7.7 0.0 3.5 2 1 1 4 4 4 3 ATP-sulfurylase DUF3313 PF11769.8 KIK51028.1 - 0.06 13.2 0.1 1.7 8.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3313) Proteasome_A_N PF10584.9 KIK51028.1 - 0.11 12.2 3.6 21 4.9 0.1 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Asp_protease_2 PF13650.6 KIK51030.1 - 4.6e-06 27.2 0.0 9.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK51030.1 - 9.1e-06 26.2 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease WD40 PF00400.32 KIK51037.1 - 3.6e-115 372.6 79.3 3e-10 40.5 0.5 12.9 13 0 0 13 13 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51037.1 - 7.9e-47 157.5 1.8 0.018 15.3 0.0 12.3 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51037.1 - 1.1e-23 83.7 6.0 0.42 9.5 0.0 11.1 2 2 9 12 12 12 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51037.1 - 2.3e-17 62.4 22.7 1.2 9.2 0.0 12.4 12 0 0 12 12 12 4 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK51037.1 - 1.1e-10 41.7 0.1 2.1e-10 40.7 0.1 1.4 1 1 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KIK51037.1 - 3e-08 33.4 0.0 20 4.4 0.0 8.6 8 2 0 10 10 10 0 WD40-like domain Nup160 PF11715.8 KIK51037.1 - 1.6e-06 27.1 7.2 9.2 4.8 0.0 8.4 8 1 2 10 10 10 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK51037.1 - 2.4e-06 27.5 0.0 0.14 12.0 0.0 3.8 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK51037.1 - 8e-06 24.5 0.0 2.2 6.5 0.0 5.9 1 1 5 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK51037.1 - 3.1e-05 24.4 0.0 6.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Cuticle_4 PF15955.5 KIK51037.1 - 0.0001 22.9 6.3 4.2 8.1 0.0 7.0 9 0 0 9 9 7 1 Cuticle protein Peptidase_S9_N PF02897.15 KIK51037.1 - 0.00015 20.7 3.1 2.7 6.7 0.0 5.4 1 1 3 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40_3 PF15911.5 KIK51037.1 - 0.00085 19.3 7.5 1.1e+02 2.9 0.0 8.5 10 0 0 10 10 10 0 WD domain, G-beta repeat Me-amine-dh_H PF06433.11 KIK51037.1 - 0.0052 15.7 0.0 10 4.9 0.0 4.1 4 0 0 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) Thymidylate_kin PF02223.17 KIK51037.1 - 0.0082 15.8 0.5 4.2 7.0 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase ATPase_2 PF01637.18 KIK51037.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KIK51037.1 - 0.014 16.0 1.3 0.074 13.6 1.3 2.1 1 1 0 1 1 1 0 AAA domain PQQ_2 PF13360.6 KIK51037.1 - 0.019 14.6 13.9 3.7 7.1 2.3 4.1 1 1 2 3 3 3 0 PQQ-like domain Phytochelatin_C PF09328.10 KIK51037.1 - 0.019 14.3 0.7 0.031 13.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) AAA PF00004.29 KIK51037.1 - 0.033 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK51037.1 - 0.033 14.6 0.0 0.097 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KIK51037.1 - 0.041 13.0 0.1 0.071 12.2 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KIK51037.1 - 0.049 13.8 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK51037.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIK51037.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK51037.1 - 0.063 12.5 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KIK51037.1 - 0.091 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 KIK51037.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KIK51037.1 - 0.11 13.1 0.0 0.28 11.7 0.0 1.7 2 0 0 2 2 1 0 ABC transporter DUF87 PF01935.17 KIK51037.1 - 0.81 9.7 2.6 0.56 10.3 0.5 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain DUF390 PF04094.14 KIK51039.1 - 0.063 11.6 5.4 0.087 11.1 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF3552 PF12072.8 KIK51040.1 - 0.00071 19.1 3.4 0.0015 18.0 3.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF390 PF04094.14 KIK51040.1 - 0.0038 15.6 11.8 0.0053 15.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF390) NACHT PF05729.12 KIK51041.1 - 0.00029 20.8 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK51041.1 - 0.039 13.1 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KIK51041.1 - 0.046 14.1 0.0 0.067 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Torsin PF06309.11 KIK51041.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Torsin APS_kinase PF01583.20 KIK51041.1 - 0.17 11.8 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Rtt106_N PF18215.1 KIK51044.1 - 0.14 11.9 0.0 1.3 8.8 0.0 2.0 1 1 1 2 2 2 0 Histone chaperone Rtt106 N-terminal domain DUF3552 PF12072.8 KIK51045.1 - 3.8e-05 23.2 160.8 0.0054 16.2 4.2 13.1 3 2 10 14 14 14 10 Domain of unknown function (DUF3552) LRAT PF04970.13 KIK51045.1 - 4.1 7.7 5.6 1.8 8.9 0.8 3.0 2 0 0 2 2 2 0 Lecithin retinol acyltransferase zf-RVT PF13966.6 KIK51046.1 - 0.033 14.9 0.0 0.21 12.4 0.0 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF3552 PF12072.8 KIK51047.1 - 0.043 13.2 55.9 0.14 11.5 25.6 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) KR PF08659.10 KIK51047.1 - 0.37 10.7 3.6 3.2 7.6 1.4 2.9 1 1 2 3 3 3 0 KR domain Ank_2 PF12796.7 KIK51048.1 - 4.1e-43 145.9 35.6 1.4e-12 48.0 1.4 5.8 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK51048.1 - 2.9e-31 107.4 7.5 4e-08 33.6 0.0 8.2 4 3 5 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK51048.1 - 4.9e-28 94.1 12.2 0.0048 17.3 0.1 10.0 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KIK51048.1 - 5.2e-18 64.6 25.9 0.00019 21.8 0.1 8.8 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KIK51048.1 - 5.1e-17 61.7 12.5 0.00011 22.4 0.0 7.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.12 KIK51048.1 - 2.8e-10 40.4 0.0 7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK51048.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK51048.1 - 0.065 13.3 0.5 5.1 7.1 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK51048.1 - 0.072 13.5 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 KIK51049.1 - 8.6e-27 92.9 6.8 8.9e-08 32.7 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51049.1 - 6.2e-11 42.4 0.0 0.0073 16.6 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51049.1 - 0.01 14.8 0.0 4.7 6.1 0.0 2.9 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KIK51049.1 - 0.047 12.8 0.1 0.46 9.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) SIR2 PF02146.17 KIK51052.1 - 2.4e-22 79.7 0.1 1.3e-18 67.5 0.0 2.3 1 1 1 2 2 2 2 Sir2 family CDC45 PF02724.14 KIK51052.1 - 0.0068 14.8 0.0 0.0088 14.4 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein CENP-Q PF13094.6 KIK51052.1 - 0.049 13.8 3.1 0.079 13.2 3.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HTH_Tnp_1 PF01527.20 KIK51052.1 - 3.7 7.9 5.4 11 6.4 3.8 2.5 2 1 0 2 2 2 0 Transposase MRP-S27 PF10037.9 KIK51053.1 - 0.1 11.5 10.5 0.12 11.2 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF3552 PF12072.8 KIK51053.1 - 0.18 11.2 24.6 0.054 12.9 18.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) UPF0242 PF06785.11 KIK51053.1 - 1.9 8.5 13.0 0.78 9.8 10.9 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Hid1 PF12722.7 KIK51053.1 - 2.9 5.9 7.0 3.2 5.8 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF390 PF04094.14 KIK51053.1 - 5.8 5.1 21.4 6.2 5.0 21.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) CIDR1_gamma PF18562.1 KIK51055.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma DUF3552 PF12072.8 KIK51058.1 - 0.00066 19.1 7.5 0.0011 18.5 7.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF390 PF04094.14 KIK51058.1 - 0.0036 15.7 12.6 0.0071 14.7 12.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF390) NACHT PF05729.12 KIK51059.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK51059.1 - 2.2e-05 24.8 0.0 2.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KIK51059.1 - 0.00027 21.4 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KIK51059.1 - 0.0011 18.3 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KIK51059.1 - 0.0032 18.0 0.0 0.0041 17.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 KIK51059.1 - 0.0038 17.1 0.1 0.0073 16.2 0.1 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK51059.1 - 0.0067 15.6 0.0 0.0092 15.2 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain DnaB_C PF03796.15 KIK51059.1 - 0.023 14.0 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 KIK51059.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ParA PF10609.9 KIK51059.1 - 0.054 12.9 0.5 0.078 12.4 0.1 1.4 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 KIK51059.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein CbiA PF01656.23 KIK51059.1 - 0.071 13.2 0.4 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KIK51059.1 - 0.076 13.3 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK51059.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Torsin PF06309.11 KIK51059.1 - 0.15 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.6 KIK51059.1 - 0.18 11.4 0.1 0.59 9.7 0.0 1.7 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK51059.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 1 0 1 1 1 0 NTPase Cytidylate_kin PF02224.18 KIK51059.1 - 0.19 11.4 0.5 0.48 10.1 0.5 1.6 1 1 0 1 1 1 0 Cytidylate kinase DUF3552 PF12072.8 KIK51060.1 - 9.4e-06 25.2 11.4 0.0024 17.3 1.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Borrelia_P83 PF05262.11 KIK51060.1 - 0.13 10.7 6.4 0.18 10.2 6.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF16 PF01519.16 KIK51060.1 - 0.15 12.5 0.3 28 5.3 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function DUF16 DUF390 PF04094.14 KIK51060.1 - 9.2 4.4 26.4 3.7 5.7 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF390) SIR2 PF02146.17 KIK51061.1 - 1.8e-12 47.6 0.0 3.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Sir2 family SEEEED PF14797.6 KIK51061.1 - 0.013 15.6 16.2 0.019 15.1 16.2 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex TPP_enzyme_M PF00205.22 KIK51061.1 - 0.13 12.0 0.1 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CDC45 PF02724.14 KIK51061.1 - 0.4 8.9 4.1 0.5 8.6 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 KIK51061.1 - 1.6 8.2 5.3 1.9 7.9 5.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2235 PF09994.9 KIK51064.1 - 7.5e-78 261.8 0.0 9.2e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SIR2 PF02146.17 KIK51065.1 - 9.5e-18 64.7 0.1 1.3e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 Sir2 family Trp_syntA PF00290.20 KIK51065.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Presenilin PF01080.17 KIK51066.1 - 0.012 14.4 0.8 0.013 14.3 0.8 1.0 1 0 0 1 1 1 0 Presenilin DUF3552 PF12072.8 KIK51069.1 - 5.4e-17 61.9 176.8 6.4e-05 22.5 4.7 13.1 2 1 12 14 14 14 11 Domain of unknown function (DUF3552) SIR2 PF02146.17 KIK51070.1 - 2.6e-53 180.6 0.0 4e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family SEEEED PF14797.6 KIK51070.1 - 0.0061 16.7 18.2 0.0091 16.2 18.2 1.1 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex TPP_enzyme_M PF00205.22 KIK51070.1 - 0.022 14.5 0.1 0.12 12.1 0.0 2.2 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Lin-8 PF03353.15 KIK51070.1 - 0.33 10.5 5.0 0.45 10.0 5.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 KIK51070.1 - 2.3 6.4 5.3 3.1 6.0 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 KIK51071.1 - 1.7e-09 37.4 0.3 3.5e-09 36.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK51071.1 - 8.1e-09 35.2 0.1 2.1e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Utp8 PF10395.9 KIK51071.1 - 0.074 11.6 0.0 0.091 11.2 0.0 1.1 1 0 0 1 1 1 0 Utp8 family Serglycin PF04360.12 KIK51071.1 - 0.44 10.5 2.0 1 9.3 2.0 1.6 1 0 0 1 1 1 0 Serglycin DEAD PF00270.29 KIK51072.1 - 1.4e-45 155.2 0.0 2.5e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK51072.1 - 6e-30 103.9 0.0 1.3e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK51072.1 - 0.042 13.1 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KIK51072.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KIK51072.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_C14 PF00656.22 KIK51073.1 - 4.3e-17 62.9 0.1 1.4e-15 58.0 0.0 1.9 1 1 1 2 2 2 1 Caspase domain RHH_1 PF01402.21 KIK51073.1 - 0.14 12.2 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF218 PF02698.17 KIK51073.1 - 0.14 12.2 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain HARE-HTH PF05066.13 KIK51073.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain ACP_PD PF04336.12 KIK51073.1 - 0.17 12.3 0.0 0.5 10.8 0.0 1.8 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Retrotrans_gag PF03732.17 KIK51076.1 - 0.00064 19.9 0.5 0.001 19.3 0.5 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Dehydratase_hem PF13816.6 KIK51076.1 - 0.036 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase PARP PF00644.20 KIK51077.1 - 0.00026 20.6 0.1 0.025 14.2 0.0 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Peptidase_C14 PF00656.22 KIK51078.1 - 1.6e-16 61.0 0.0 4.6e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Caspase domain DBP10CT PF08147.12 KIK51079.1 - 0.067 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 DBP10CT (NUC160) domain WD40 PF00400.32 KIK51084.1 - 9.1e-144 463.1 35.4 1.2e-11 45.0 0.0 14.8 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51084.1 - 2e-38 130.6 7.9 0.02 15.2 0.0 12.7 2 2 12 14 14 14 8 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51084.1 - 8e-27 94.4 3.3 7.4e-05 22.7 0.1 6.4 1 1 8 9 9 9 9 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK51084.1 - 4.1e-13 49.3 3.6 1.7 7.9 0.0 10.1 8 4 3 11 11 11 1 WD40-like domain PD40 PF07676.12 KIK51084.1 - 1.6e-12 47.0 0.0 25 4.9 0.0 11.7 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK51084.1 - 4.1e-10 39.1 14.6 11 4.9 0.0 10.9 2 2 10 12 12 12 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK51084.1 - 7.1e-09 34.8 13.2 1.5 7.4 0.1 9.9 6 3 1 11 11 11 1 Nucleoporin Nup120/160 nos_propeller PF18764.1 KIK51084.1 - 6.9e-07 29.1 26.5 16 5.5 0.0 12.5 13 1 1 14 14 14 0 Nitrous oxide reductase propeller repeat potato_inhibit PF00280.18 KIK51084.1 - 9.8e-07 29.4 0.8 42 4.9 0.0 8.3 8 2 2 11 11 11 0 Potato inhibitor I family NHL PF01436.21 KIK51084.1 - 4.2e-05 23.4 21.5 50 4.2 0.0 12.4 14 0 0 14 14 14 0 NHL repeat Str_synth PF03088.16 KIK51084.1 - 6.9e-05 22.9 0.2 37 4.5 0.0 7.1 7 3 4 11 11 11 0 Strictosidine synthase SdiA-regulated PF06977.11 KIK51084.1 - 0.0002 20.7 0.0 3.6 6.7 0.0 4.9 2 2 4 6 6 6 1 SdiA-regulated HPS3_N PF14761.6 KIK51084.1 - 0.0011 18.5 0.1 35 3.8 0.0 5.5 4 1 2 7 7 7 0 Hermansky-Pudlak syndrome 3 Imm17 PF15562.6 KIK51084.1 - 0.0052 16.6 0.0 47 3.9 0.0 6.0 8 0 0 8 8 7 0 Immunity protein 17 Frtz PF11768.8 KIK51084.1 - 0.0092 14.3 0.0 12 4.0 0.0 5.0 5 2 3 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz GCV_T_C PF08669.11 KIK51084.1 - 0.056 13.4 8.3 3.7 7.5 0.2 5.8 5 1 1 6 6 6 0 Glycine cleavage T-protein C-terminal barrel domain Ret2_MD PF18528.1 KIK51084.1 - 0.065 13.6 0.0 62 4.1 0.0 4.5 3 2 2 6 6 6 0 RNA editing 3' terminal uridylyl transferase 2 middle domain AMPKBI PF04739.15 KIK51084.1 - 0.1 12.9 0.0 6.9 7.0 0.0 2.9 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain DsbC_N PF10411.9 KIK51084.1 - 0.44 10.0 19.0 1.7e+02 1.8 0.0 10.3 14 0 0 14 14 14 0 Disulfide bond isomerase protein N-terminus Phage_sheath_1 PF04984.14 KIK51084.1 - 2 8.2 8.8 2.4e+02 1.5 0.0 6.8 9 1 0 9 9 9 0 Phage tail sheath protein subtilisin-like domain DUF615 PF04751.14 KIK51086.1 - 0.058 13.4 0.7 0.085 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Sod_Fe_C PF02777.18 KIK51086.1 - 0.081 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Exo_endo_phos_2 PF14529.6 KIK51087.1 - 0.024 14.5 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase zf-BED PF02892.15 KIK51088.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger zf-RVT PF13966.6 KIK51089.1 - 2.5e-05 24.9 3.8 5.3e-05 23.8 3.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF4510 PF14971.6 KIK51090.1 - 0.19 12.1 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) X PF00739.19 KIK51090.1 - 1.5 8.9 6.6 0.77 9.9 4.3 1.7 1 1 1 2 2 2 0 Trans-activation protein X DDE_Tnp_4 PF13359.6 KIK51091.1 - 5.2e-19 68.4 0.0 6.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3787 PF12655.7 KIK51091.1 - 0.13 12.3 0.7 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) EPOP PF15223.6 KIK51092.1 - 0.35 10.2 10.6 0.43 9.9 10.6 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein WD40 PF00400.32 KIK51094.1 - 3.4e-95 309.4 36.3 1.3e-09 38.5 0.1 13.5 11 2 3 14 14 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51094.1 - 9.7e-20 70.7 4.1 0.21 11.9 0.0 10.0 3 3 8 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51094.1 - 8.3e-14 51.9 3.0 6.1e-05 23.0 0.1 6.5 3 2 4 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK51094.1 - 1.3e-08 34.0 13.0 0.91 8.1 0.0 7.4 2 2 6 8 8 8 5 Nucleoporin Nup120/160 PD40 PF07676.12 KIK51094.1 - 1.1e-06 28.4 1.3 63 3.7 0.0 8.4 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK51094.1 - 2.6e-05 23.7 0.5 1.8 7.8 0.1 5.6 6 1 0 6 6 6 1 WD40-like domain Ge1_WD40 PF16529.5 KIK51094.1 - 7.9e-05 21.8 1.5 8 5.3 0.0 6.2 4 2 4 8 8 8 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NHL PF01436.21 KIK51094.1 - 0.0012 18.8 7.7 81 3.5 0.0 7.9 9 0 0 9 9 9 0 NHL repeat DsbC_N PF10411.9 KIK51094.1 - 0.0035 16.8 3.6 1.5e+02 1.9 0.0 7.1 8 0 0 8 8 8 0 Disulfide bond isomerase protein N-terminus nos_propeller PF18764.1 KIK51094.1 - 0.0054 16.6 13.3 7.7 6.5 0.0 8.0 10 0 0 10 10 10 1 Nitrous oxide reductase propeller repeat DUF4596 PF15363.6 KIK51094.1 - 0.043 14.0 11.3 0.43 10.9 0.3 6.0 7 1 1 8 8 7 0 Domain of unknown function (DUF4596) DUF5018 PF16410.5 KIK51094.1 - 0.083 11.6 0.7 2.3 6.8 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF5018) SymE_toxin PF08845.10 KIK51094.1 - 0.29 11.2 13.1 13 5.9 0.3 5.1 5 0 0 5 5 5 0 Toxin SymE, type I toxin-antitoxin system GCV_T_C PF08669.11 KIK51094.1 - 0.37 10.7 4.6 3.7 7.5 0.1 4.5 4 0 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain Macoilin PF09726.9 KIK51096.1 - 2.2 6.7 4.9 2.4 6.6 4.9 1.0 1 0 0 1 1 1 0 Macoilin family GCM PF03615.15 KIK51097.1 - 0.0078 16.1 6.9 0.024 14.5 6.9 1.8 1 1 0 1 1 1 1 GCM motif protein DDE_1 PF03184.19 KIK51100.1 - 1.4e-07 31.4 0.0 1.6e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK51100.1 - 0.091 12.5 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Jnk-SapK_ap_N PF09744.9 KIK51101.1 - 0.012 15.9 2.6 0.013 15.7 2.6 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 BRD4_CDT PF17105.5 KIK51101.1 - 0.68 9.6 3.7 1.1 8.9 3.7 1.3 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DUF4218 PF13960.6 KIK51102.1 - 0.0076 15.8 0.1 0.015 14.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) PPR_1 PF12854.7 KIK51102.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 PPR repeat PPR PF01535.20 KIK51102.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 PPR repeat DDE_1 PF03184.19 KIK51107.1 - 4.2e-08 33.0 0.1 2.4e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease NUP PF06516.11 KIK51110.1 - 1.2e-127 425.4 0.0 1.4e-127 425.2 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) MARVEL PF01284.23 KIK51111.1 - 0.004 17.2 8.8 0.0058 16.7 8.8 1.3 1 1 0 1 1 1 1 Membrane-associating domain Glyco_transf_15 PF01793.16 KIK51113.1 - 6.3e-35 121.0 0.1 7.1e-35 120.8 0.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SHS2_Rpb7-N PF03876.17 KIK51113.1 - 0.034 14.5 0.0 11 6.5 0.0 2.2 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mid2 PF04478.12 KIK51115.1 - 0.00099 19.0 0.8 0.00099 19.0 0.8 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Gly-zipper_Omp PF13488.6 KIK51115.1 - 0.001 19.0 0.7 0.003 17.5 0.7 1.7 1 0 0 1 1 1 1 Glycine zipper TMEM154 PF15102.6 KIK51115.1 - 0.0057 16.6 0.0 0.0057 16.6 0.0 2.4 1 1 1 2 2 1 1 TMEM154 protein family PMP1_2 PF08114.11 KIK51115.1 - 0.015 15.1 0.5 0.03 14.0 0.5 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Adeno_E3_CR2 PF02439.15 KIK51115.1 - 0.017 14.9 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 KIK51115.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Romo1 PF10247.9 KIK51115.1 - 0.022 15.1 1.4 0.06 13.7 0.3 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Syndecan PF01034.20 KIK51115.1 - 0.033 14.1 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain TNFR_16_TM PF18422.1 KIK51115.1 - 0.05 13.6 0.6 0.086 12.8 0.6 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain FeoB_associated PF12669.7 KIK51115.1 - 0.059 13.8 0.6 0.1 13.0 0.6 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3185 PF11381.8 KIK51115.1 - 0.28 11.2 5.0 9.6 6.3 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) NAD_binding_10 PF13460.6 KIK51119.1 - 5.3e-11 42.8 0.0 5.8e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK51119.1 - 2.3e-09 37.1 0.0 2.6e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK51119.1 - 7.8e-08 31.7 0.0 8.8e-08 31.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KIK51119.1 - 6.2e-07 29.2 0.1 6.8e-07 29.1 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIK51119.1 - 7.7e-07 28.5 0.3 5.2e-05 22.5 0.1 2.0 1 1 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK51119.1 - 1.1e-06 28.2 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KIK51119.1 - 0.0014 18.5 0.4 0.029 14.3 0.4 2.0 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KIK51119.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KIK51119.1 - 0.015 14.4 0.0 0.016 14.3 0.0 1.0 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KIK51119.1 - 0.03 14.6 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KIK51119.1 - 0.036 14.2 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_15 PF01793.16 KIK51121.1 - 4.6e-126 420.5 7.3 5.6e-126 420.2 7.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase OHCU_decarbox PF09349.10 KIK51121.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 OHCU decarboxylase NUP PF06516.11 KIK51123.1 - 2.9e-131 437.4 0.1 3.3e-131 437.2 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Lustrin_cystein PF14625.6 KIK51126.1 - 0.15 12.5 7.2 0.21 12.0 7.2 1.4 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Sugar_tr PF00083.24 KIK51127.1 - 8.6e-111 371.0 20.0 1e-110 370.8 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK51127.1 - 3.6e-23 82.1 40.6 1.3e-16 60.5 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.20 KIK51128.1 - 2.7e-90 303.1 0.0 4e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AAA PF00004.29 KIK51129.1 - 7.9e-17 61.9 0.0 1.5e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK51129.1 - 0.00018 21.8 1.1 0.0057 16.9 0.1 2.9 1 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KIK51129.1 - 0.00049 20.5 0.1 0.0021 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIK51129.1 - 0.00052 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Nop14 PF04147.12 KIK51129.1 - 1.7 6.7 8.6 14 3.7 5.6 2.1 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 KIK51129.1 - 1.9 7.8 8.5 2.9 7.1 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KIK51129.1 - 3.5 5.6 5.0 5 5.1 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Astro_capsid_p PF12226.8 KIK51129.1 - 3.7 6.6 5.4 6.1 5.9 5.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 KIK51129.1 - 9.1 6.7 16.6 23 5.4 16.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Amidase PF01425.21 KIK51130.1 - 6.5e-11 41.9 0.0 7.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KIK51132.1 - 8.1e-78 262.4 0.0 2.8e-76 257.3 0.0 2.0 1 1 0 1 1 1 1 Amidase ATG13 PF10033.9 KIK51133.1 - 2.7e-38 132.0 0.0 4.4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 zf-C2H2 PF00096.26 KIK51134.1 - 5.7e-08 32.8 6.8 0.001 19.4 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK51134.1 - 4.6e-07 30.1 4.1 0.011 16.5 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIK51134.1 - 2.9e-06 27.5 1.8 0.0086 16.4 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KIK51134.1 - 2.2e-05 24.7 0.5 2.2e-05 24.7 0.5 3.0 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK51134.1 - 0.0033 17.7 13.1 0.087 13.1 0.2 3.2 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding ETX_MTX2 PF03318.13 KIK51137.1 - 0.044 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 LEA_2 PF03168.13 KIK51137.1 - 0.053 14.1 0.3 0.22 12.1 0.1 1.9 1 1 0 2 2 2 0 Late embryogenesis abundant protein PA-IIL PF07472.11 KIK51137.1 - 0.061 13.6 2.7 0.61 10.4 2.7 2.2 1 1 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) CotE PF10628.9 KIK51137.1 - 0.063 12.9 6.7 0.081 12.6 6.7 1.1 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) Hus1 PF04005.12 KIK51137.1 - 0.24 10.5 2.1 0.3 10.2 2.1 1.1 1 0 0 1 1 1 0 Hus1-like protein Cadherin-like PF12733.7 KIK51137.1 - 3.3 8.3 7.2 4.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain Polysacc_deac_1 PF01522.21 KIK51142.1 - 3.4e-26 91.6 0.0 5.1e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Transferase PF02458.15 KIK51143.1 - 0.054 12.2 0.0 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 Transferase family Lipase_GDSL PF00657.22 KIK51144.1 - 4e-07 30.2 0.0 5.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK51144.1 - 0.00058 20.3 0.9 0.002 18.5 0.9 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family p450 PF00067.22 KIK51147.1 - 1.5e-72 244.8 0.0 1.8e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KIK51148.1 - 5.9e-28 97.3 2.8 8.5e-28 96.8 2.8 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK51148.1 - 0.022 14.9 0.2 0.052 13.7 0.2 1.6 1 0 0 1 1 1 0 Berberine and berberine like Aldo_ket_red PF00248.21 KIK51149.1 - 8.6e-45 153.2 0.0 1.4e-40 139.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family ADH_zinc_N PF00107.26 KIK51150.1 - 5.3e-12 45.8 0.0 1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK51150.1 - 2.8e-07 30.4 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK51150.1 - 0.049 14.7 0.0 0.073 14.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UbiA PF01040.18 KIK51151.1 - 1.5e-21 76.9 14.7 1.9e-21 76.5 14.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KIK51152.1 - 4.7e-75 253.1 0.0 5.4e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KIK51153.1 - 2e-23 82.7 0.6 2.8e-23 82.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK51153.1 - 0.023 14.8 0.1 0.093 12.8 0.1 2.1 2 0 0 2 2 2 0 Berberine and berberine like p450 PF00067.22 KIK51155.1 - 1e-39 136.6 0.0 1.3e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fe_dep_repr_C PF02742.15 KIK51155.1 - 0.019 15.0 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain UCR_hinge PF02320.16 KIK51156.1 - 7.5e-22 77.3 8.0 7.5e-22 77.3 8.0 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Brr6_like_C_C PF10104.9 KIK51156.1 - 0.021 14.6 0.2 0.021 14.6 0.2 1.6 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain ORC_WH_C PF18137.1 KIK51156.1 - 0.032 14.3 3.0 0.042 13.9 3.0 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal PAF PF15715.5 KIK51156.1 - 0.073 13.7 4.0 0.085 13.5 4.0 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain RNA_pol_Rpc4 PF05132.14 KIK51156.1 - 0.51 10.8 4.9 0.59 10.5 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Folate_carrier PF01770.18 KIK51156.1 - 0.51 9.0 0.9 0.58 8.8 0.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF3484 PF11983.8 KIK51156.1 - 0.83 10.8 10.1 1.5 10.0 10.1 1.4 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch DUF3391 PF11871.8 KIK51156.1 - 0.89 10.1 5.9 1 9.9 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) FtsJ PF01728.19 KIK51157.1 - 2.1e-13 50.8 0.0 3.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KIK51157.1 - 0.16 12.7 0.0 1.2 9.9 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Vps62 PF06101.11 KIK51158.1 - 3.3e-07 29.0 0.9 4.9e-07 28.4 0.2 1.6 1 1 1 2 2 2 1 Vacuolar protein sorting-associated protein 62 FtsJ PF01728.19 KIK51159.1 - 7.2e-09 36.0 0.0 9.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KIK51159.1 - 0.19 12.5 0.0 1.1 10.0 0.0 2.1 1 1 0 2 2 2 0 Methyltransferase domain FtsX PF02687.21 KIK51160.1 - 0.012 16.0 2.1 0.047 14.2 0.9 2.0 2 0 0 2 2 2 0 FtsX-like permease family DUF1129 PF06570.11 KIK51160.1 - 0.021 14.3 1.6 0.028 13.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Vps62 PF06101.11 KIK51161.1 - 2.8e-11 42.4 2.8 1.6e-10 39.9 0.1 2.3 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 62 Toxin_7 PF05980.12 KIK51162.1 - 0.48 10.7 5.0 0.97 9.7 5.0 1.6 1 1 0 1 1 1 0 Toxin 7 p450 PF00067.22 KIK51163.1 - 2.7e-35 122.0 0.0 2.9e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4523 PF15023.6 KIK51164.1 - 0.037 13.9 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Terpene_synth_C PF03936.16 KIK51164.1 - 0.091 12.1 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain NPL PF17800.1 KIK51165.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 Nucleoplasmin-like domain Arm PF00514.23 KIK51166.1 - 2.1e-36 122.8 0.2 1.2e-11 44.2 0.0 4.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK51166.1 - 2.1e-09 37.7 0.6 5.9e-06 26.7 0.1 3.1 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KIK51166.1 - 1.1e-07 32.1 0.0 0.01 16.2 0.0 3.0 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.22 KIK51166.1 - 0.00017 21.6 0.3 0.36 11.2 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat RICTOR_V PF14668.6 KIK51166.1 - 0.00035 20.7 1.1 0.039 14.2 0.0 2.7 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KIK51166.1 - 0.012 16.2 0.1 23 6.0 0.0 3.5 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat SpoVAB PF13782.6 KIK51166.1 - 0.2 12.0 0.0 0.69 10.2 0.0 1.8 1 1 1 2 2 2 0 Stage V sporulation protein AB Arm_3 PF16186.5 KIK51167.1 - 2e-18 65.7 0.1 2.9e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Atypical Arm repeat nec1 PF10379.9 KIK51167.1 - 0.016 14.7 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Virulence protein nec1 MUG113 PF13455.6 KIK51169.1 - 2.7e-08 34.4 0.1 2.3e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK51169.1 - 7.4e-05 23.2 0.0 0.00073 20.0 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain KDZ PF18758.1 KIK51171.1 - 0.0022 17.7 0.3 0.0023 17.6 0.3 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TFIIA PF03153.13 KIK51173.1 - 5.6 6.9 6.7 6.7 6.6 6.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PT PF04886.12 KIK51175.1 - 0.19 11.3 3.3 0.45 10.1 3.3 1.5 1 0 0 1 1 1 0 PT repeat FTA4 PF13093.6 KIK51175.1 - 0.88 9.4 3.6 5.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 YlqD PF11068.8 KIK51176.1 - 0.23 11.8 3.4 0.63 10.4 3.4 1.7 1 0 0 1 1 1 0 YlqD protein F-box-like PF12937.7 KIK51179.1 - 6.5e-08 32.3 0.2 3.8e-07 29.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK51180.1 - 5e-05 23.1 0.2 0.00016 21.5 0.2 1.9 1 1 0 1 1 1 1 F-box-like Glyco_transf_8 PF01501.20 KIK51181.1 - 3.7e-28 98.8 0.0 1e-27 97.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 KIK51181.1 - 2.8e-13 50.8 0.0 8.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 KIK51181.1 - 0.0002 20.9 0.0 0.00089 18.7 0.0 2.1 1 1 0 1 1 1 1 Glucosyltransferase 24 Epimerase PF01370.21 KIK51182.1 - 2.1e-43 148.5 0.0 3e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK51182.1 - 2.1e-22 80.0 0.0 5.1e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIK51182.1 - 4.8e-18 65.2 0.1 7.6e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glycos_transf_2 PF00535.26 KIK51182.1 - 1.7e-14 54.0 0.1 4e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 NAD_binding_10 PF13460.6 KIK51182.1 - 3.6e-10 40.0 0.0 6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIK51182.1 - 1.6e-07 30.8 0.1 3.7e-05 23.0 1.2 3.1 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Glyco_tranf_2_3 PF13641.6 KIK51182.1 - 3.6e-06 27.0 0.0 9.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RmlD_sub_bind PF04321.17 KIK51182.1 - 6.2e-05 22.2 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIK51182.1 - 7e-05 22.1 0.0 0.019 14.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Glyco_tranf_2_2 PF10111.9 KIK51182.1 - 0.00043 19.9 0.0 0.00071 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NmrA PF05368.13 KIK51182.1 - 0.0026 17.3 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KIK51182.1 - 0.025 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 KR domain Glyco_hydro_16 PF00722.21 KIK51183.1 - 1e-08 34.8 0.0 7.5e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 BTB PF00651.31 KIK51186.1 - 9e-10 38.8 0.1 1.6e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain FEZ PF07763.13 KIK51189.1 - 0.029 14.1 0.7 0.052 13.3 0.7 1.3 1 0 0 1 1 1 0 FEZ-like protein DUF2262 PF10020.9 KIK51189.1 - 0.039 14.3 0.2 0.058 13.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Ribosomal_60s PF00428.19 KIK51189.1 - 0.25 12.0 3.1 0.54 10.9 2.1 2.2 1 1 0 1 1 1 0 60s Acidic ribosomal protein YbgT_YccB PF08173.11 KIK51190.1 - 8.2 6.7 7.0 27 5.0 0.9 2.7 2 0 0 2 2 2 0 Membrane bound YbgT-like protein BCOR PF15808.5 KIK51191.1 - 0.034 14.4 3.3 0.076 13.2 3.3 1.6 1 1 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region AAA_2 PF07724.14 KIK51191.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Peptidase_S10 PF00450.22 KIK51192.1 - 2.9e-106 356.4 0.0 3.7e-106 356.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1793 PF08760.11 KIK51193.1 - 4.4e-14 53.3 0.2 5.2e-14 53.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIK51198.1 - 5.5e-09 35.9 0.5 7e-09 35.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) Bac_rhamnosid6H PF17389.2 KIK51198.1 - 0.0082 15.4 0.1 0.014 14.7 0.1 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KIK51199.1 - 2.8e-65 220.3 1.4 3.7e-64 216.6 0.3 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KIK51199.1 - 0.0011 18.4 0.2 0.003 17.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DUF1793 PF08760.11 KIK51200.1 - 1.6e-09 38.4 0.0 1.8e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) PRIMA1 PF16101.5 KIK51201.1 - 3.1 7.9 5.2 4.2 7.4 2.0 2.5 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Aminotran_4 PF01063.19 KIK51205.1 - 9.1e-30 104.2 0.0 1e-28 100.7 0.0 2.0 1 1 0 1 1 1 1 Amino-transferase class IV Protocadherin PF08374.11 KIK51206.1 - 0.083 12.9 0.2 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 Protocadherin Adeno_E3_CR2 PF02439.15 KIK51206.1 - 0.095 12.5 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5127 PF17168.4 KIK51207.1 - 3.7e-63 213.4 2.0 6.2e-63 212.6 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK51207.1 - 1.3e-41 142.1 0.2 4.8e-41 140.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK51207.1 - 7.2e-21 75.3 2.5 1.4e-20 74.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF1859 PF08948.10 KIK51207.1 - 0.072 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) T2SSJ PF11612.8 KIK51209.1 - 0.03 14.5 0.4 0.059 13.6 0.4 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J F-box-like PF12937.7 KIK51210.1 - 1.2e-06 28.3 0.5 4e-06 26.6 0.5 2.0 1 0 0 1 1 1 1 F-box-like PBP PF01161.20 KIK51211.1 - 4.8e-19 69.0 0.0 5.9e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Alpha-amylase PF00128.24 KIK51212.1 - 1.7e-16 60.8 0.0 1.1e-14 54.7 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain NUDE_C PF04880.13 KIK51214.1 - 5.8 7.4 6.9 6.5 7.2 6.9 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region WD40 PF00400.32 KIK51215.1 - 4e-16 59.1 3.3 2.1e-08 34.7 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.12 KIK51215.1 - 1.2e-09 38.3 0.1 2.4e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KIK51215.1 - 5.3e-07 29.8 0.1 0.013 15.7 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KIK51215.1 - 6.4e-06 26.7 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK51215.1 - 0.0004 20.4 2.3 0.00045 20.2 0.0 2.1 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK51215.1 - 0.0067 15.6 0.0 0.017 14.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK51215.1 - 0.013 15.9 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KIK51215.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK51215.1 - 0.02 15.5 0.0 0.076 13.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 KIK51215.1 - 0.023 14.9 0.0 0.082 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK51215.1 - 0.041 14.2 0.0 0.32 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain WD40_like PF17005.5 KIK51215.1 - 0.044 13.1 0.0 0.14 11.4 0.0 1.9 1 1 0 1 1 1 0 WD40-like domain AAA PF00004.29 KIK51215.1 - 0.071 13.5 0.2 0.46 10.9 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK51215.1 - 0.076 13.5 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KIK51215.1 - 0.09 12.7 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 KIK51215.1 - 1.8 8.6 4.7 4.4 7.3 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain ASPRs PF17641.2 KIK51218.1 - 0.14 12.4 0.1 0.19 12.0 0.1 1.3 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Peptidase_S49_N PF08496.10 KIK51220.1 - 0.00012 22.2 0.4 0.00031 20.8 0.4 1.6 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK51220.1 - 0.006 15.5 11.3 0.0091 14.9 11.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KIK51220.1 - 0.016 15.2 11.2 0.097 12.7 1.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KIK51220.1 - 0.027 14.7 1.4 0.068 13.4 1.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MPS2 PF17060.5 KIK51220.1 - 0.044 13.0 0.6 0.064 12.5 0.6 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Transcrip_act PF04949.13 KIK51220.1 - 0.066 13.1 2.5 0.13 12.1 2.5 1.4 1 0 0 1 1 1 0 Transcriptional activator Prp19 PF08606.11 KIK51220.1 - 0.072 13.1 0.4 0.34 10.9 0.4 2.2 1 0 0 1 1 1 0 Prp19/Pso4-like FAM76 PF16046.5 KIK51220.1 - 0.089 12.1 2.5 0.13 11.6 2.5 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 KIK51220.1 - 0.16 12.0 1.7 0.35 10.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Spc34 PF08657.10 KIK51220.1 - 0.21 11.4 3.0 0.18 11.5 1.7 1.6 2 0 0 2 2 1 0 DASH complex subunit Spc34 Sec2p PF06428.11 KIK51220.1 - 0.33 10.9 12.6 0.041 13.9 4.2 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p PKcGMP_CC PF16808.5 KIK51220.1 - 0.74 9.7 5.2 8.1 6.4 0.2 3.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YscO-like PF16789.5 KIK51220.1 - 1.2 9.1 7.7 2.2 8.3 7.7 1.3 1 0 0 1 1 1 0 YscO-like protein DUF3837 PF12939.7 KIK51220.1 - 1.4 9.3 3.6 4 7.9 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) Lebercilin PF15619.6 KIK51220.1 - 1.6 8.3 11.7 3.9 7.1 11.7 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KIK51220.1 - 3.9 7.5 11.9 6.2 6.9 4.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 KIK51220.1 - 5 7.3 9.1 26 5.0 3.5 3.1 2 1 1 3 3 3 0 bZIP transcription factor DUF3450 PF11932.8 KIK51220.1 - 5.5 6.2 11.6 0.17 11.2 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KIK51220.1 - 5.8 7.3 12.5 5.2 7.5 1.3 2.8 1 1 0 2 2 2 0 Csm1 N-terminal domain Lectin_N PF03954.14 KIK51220.1 - 7.1 6.4 8.0 3.5 7.4 3.5 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain WD40 PF00400.32 KIK51222.1 - 2.4e-21 75.6 8.4 5.4e-07 30.2 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51222.1 - 6.5e-07 29.6 0.1 0.25 11.7 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK51222.1 - 0.0033 16.8 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 KIK51222.1 - 0.0052 15.5 0.4 1.5 7.4 0.0 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_16 PF13191.6 KIK51223.1 - 2e-06 28.3 0.0 2.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK51223.1 - 7.2e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK51223.1 - 0.00025 21.0 0.0 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK51223.1 - 0.00098 18.4 0.1 0.0011 18.2 0.1 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KIK51223.1 - 0.0021 17.8 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK51223.1 - 0.0022 18.4 0.2 0.0064 16.9 0.2 2.0 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KIK51223.1 - 0.003 18.1 0.1 0.0044 17.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIK51223.1 - 0.0049 16.8 0.1 0.074 12.9 0.1 2.0 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.6 KIK51223.1 - 0.0056 17.0 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK51223.1 - 0.01 16.4 0.0 0.013 16.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 KIK51223.1 - 0.017 15.5 0.3 0.042 14.3 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK51223.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KIK51223.1 - 0.034 13.9 0.1 0.062 13.0 0.1 1.4 1 1 0 1 1 1 0 Cytidylate kinase ATPase PF06745.13 KIK51223.1 - 0.06 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC PIF1 PF05970.14 KIK51223.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 KIK51223.1 - 0.091 12.7 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 KIK51223.1 - 0.096 12.8 0.2 0.12 12.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK51223.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF1048 PF06304.11 KIK51224.1 - 0.0072 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) Syntaxin-18_N PF10496.9 KIK51227.1 - 0.043 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-LYAR PF08790.11 KIK51227.1 - 0.11 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DarA_C PF18789.1 KIK51228.1 - 1.2 9.5 6.7 0.96 9.8 0.5 3.2 3 1 1 4 4 4 0 Defence against restriction A C-terminal NPR3 PF03666.13 KIK51228.1 - 2.3 6.9 11.8 2.8 6.6 11.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Retrotran_gag_2 PF14223.6 KIK51230.1 - 1.1e-10 41.3 0.2 1.8e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KIK51230.1 - 1.8e-05 24.6 7.1 4.3e-05 23.4 7.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Arm PF00514.23 KIK51232.1 - 1.3e-32 110.8 0.7 1.4e-12 47.2 0.1 3.3 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK51232.1 - 6.8e-10 39.2 0.1 2.6e-07 31.0 0.0 3.1 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KIK51232.1 - 2.4e-07 31.1 0.0 0.0017 18.7 0.0 2.9 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KIK51232.1 - 2.2e-06 27.4 0.0 0.004 17.3 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat RICTOR_V PF14668.6 KIK51232.1 - 0.0079 16.4 0.5 1.2 9.4 0.1 2.7 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KIK51232.1 - 0.067 13.9 0.1 9.3 7.3 0.0 3.3 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 KIK51233.1 - 4.8e-41 137.6 12.4 3.1e-11 42.9 0.0 6.0 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK51233.1 - 3.9e-11 43.2 0.0 0.059 13.9 0.1 4.3 3 1 1 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 KIK51233.1 - 2.6e-10 40.5 0.0 1.4e-05 25.4 0.0 3.1 1 1 3 4 4 4 3 HEAT repeats HEAT PF02985.22 KIK51233.1 - 1e-08 34.7 0.7 0.039 14.2 0.0 4.6 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.20 KIK51233.1 - 0.0013 17.4 0.0 0.067 11.7 0.0 2.2 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KIK51233.1 - 0.0022 18.1 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 2 V-ATPase subunit H NopRA1 PF16201.5 KIK51233.1 - 0.016 14.8 0.1 10 5.6 0.0 2.8 2 1 1 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Katanin_con80 PF13925.6 KIK51233.1 - 0.043 13.9 0.0 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 con80 domain of Katanin V-ATPase_H_N PF03224.14 KIK51233.1 - 0.16 11.2 0.1 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 V-ATPase subunit H UPF0560 PF10577.9 KIK51235.1 - 0.067 11.7 2.3 0.083 11.4 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MRI PF15325.6 KIK51235.1 - 0.73 10.9 6.7 0.51 11.5 5.2 1.5 1 1 0 1 1 1 0 Modulator of retrovirus infection WD40 PF00400.32 KIK51239.1 - 3.1e-29 100.6 11.5 3.8e-11 43.4 0.4 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51239.1 - 3.2e-12 46.6 0.0 0.0015 18.8 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51239.1 - 1.5e-08 34.0 0.1 0.11 11.5 0.0 3.0 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51239.1 - 9.5e-07 28.6 0.2 1.2 9.2 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat rOmpB PF12334.8 KIK51239.1 - 0.00039 20.0 1.1 4.4 6.7 0.0 3.1 2 1 1 3 3 3 2 Rickettsia outer membrane protein B Gmad1 PF10647.9 KIK51239.1 - 0.0011 18.8 0.2 2.1 8.0 0.0 3.0 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain potato_inhibit PF00280.18 KIK51239.1 - 0.013 16.2 0.0 24 5.7 0.0 3.0 3 0 0 3 3 3 0 Potato inhibitor I family WD40_3 PF15911.5 KIK51239.1 - 0.014 15.4 0.7 39 4.4 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Cuticle_4 PF15955.5 KIK51239.1 - 0.026 15.2 0.3 8.5 7.2 0.1 3.1 3 0 0 3 3 3 0 Cuticle protein WD40_like PF17005.5 KIK51239.1 - 0.06 12.7 0.0 4.1 6.6 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain Frtz PF11768.8 KIK51239.1 - 0.17 10.1 0.0 3.7 5.8 0.0 2.5 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK51239.1 - 0.54 10.0 2.1 65 3.3 0.1 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature gag_pre-integrs PF13976.6 KIK51240.1 - 9.7e-06 25.4 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain Plavaka PF18759.1 KIK51245.1 - 7.6e-13 48.4 0.0 9.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase OTT_1508_deam PF14441.6 KIK51246.1 - 1.5e-06 28.1 0.0 4.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 OTT_1508-like deaminase TRAPP PF04051.16 KIK51247.1 - 4.1e-23 81.7 0.0 4.4e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DHC_N1 PF08385.12 KIK51248.1 - 2.3e-31 109.1 1.2 3.1e-24 85.6 0.0 3.2 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 1 JmjC PF02373.22 KIK51249.1 - 0.043 14.2 0.0 0.18 12.3 0.0 2.2 1 0 0 1 1 1 0 JmjC domain, hydroxylase FtsK_SpoIIIE PF01580.18 KIK51252.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KIK51252.1 - 0.013 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RHSP PF07999.11 KIK51252.1 - 0.017 14.0 0.1 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon hot spot protein AAA_25 PF13481.6 KIK51252.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIK51252.1 - 0.17 11.4 0.0 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Rhodanese PF00581.20 KIK51253.1 - 6.1e-05 23.5 0.0 0.00022 21.7 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DGF-1_C PF11040.8 KIK51253.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Y_phosphatase PF00102.27 KIK51254.1 - 4.2e-47 160.7 0.0 5e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KIK51254.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KIK51254.1 - 0.0048 16.9 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Dor1 PF04124.12 KIK51256.1 - 4.1e-30 104.6 0.1 5.1e-22 78.0 0.1 2.2 2 0 0 2 2 2 2 Dor1-like family COG2 PF06148.11 KIK51256.1 - 0.21 11.7 0.8 0.47 10.5 0.3 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KIK51256.1 - 0.21 11.6 1.2 5.1 7.1 1.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Clathrin_lg_ch PF01086.17 KIK51257.1 - 1.4e-41 143.0 5.1 9e-41 140.4 5.1 1.8 1 1 0 1 1 1 1 Clathrin light chain Trp_repressor PF01371.19 KIK51257.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein MALT1_Ig PF18703.1 KIK51257.1 - 0.096 12.7 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 MALT1 Ig-like domain DUF4407 PF14362.6 KIK51257.1 - 1.1 8.6 5.2 1.3 8.3 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIP5K PF01504.18 KIK51258.1 - 3.4e-19 69.1 0.0 3.6e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DNA_topoisoIV PF00521.20 KIK51259.1 - 6e-39 134.1 1.5 2.2e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIK51259.1 - 2.2e-33 115.3 1.5 2.2e-33 115.3 1.5 2.2 2 1 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_topoisoIV PF00521.20 KIK51260.1 - 0.00071 18.6 0.1 0.00086 18.3 0.1 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DUF4906 PF16249.5 KIK51260.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) LRR_8 PF13855.6 KIK51261.1 - 5.5e-19 67.7 6.5 1.5e-12 47.0 1.1 3.4 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KIK51261.1 - 2.3e-16 59.6 18.1 2.5e-07 30.9 2.3 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK51261.1 - 0.00026 20.8 3.8 0.11 12.6 0.5 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KIK51261.1 - 0.0065 16.8 14.5 2.9 8.8 1.0 5.5 5 3 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KIK51261.1 - 0.017 14.6 0.1 0.043 13.3 0.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeat OTT_1508_deam PF14441.6 KIK51262.1 - 6.2e-07 29.3 0.1 2.1e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 OTT_1508-like deaminase Tail_tube PF10618.9 KIK51267.1 - 0.094 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Phage tail tube protein AAA_16 PF13191.6 KIK51268.1 - 0.0028 18.0 0.0 0.0032 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KIK51268.1 - 0.024 14.5 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK51268.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KIK51268.1 - 0.024 14.8 0.1 0.037 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK51268.1 - 0.036 14.5 0.1 0.058 13.8 0.1 1.6 1 1 0 1 1 1 0 RNA helicase AAA PF00004.29 KIK51268.1 - 0.039 14.4 0.1 0.057 13.9 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK51268.1 - 0.066 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KIK51268.1 - 0.083 12.8 0.6 0.26 11.2 0.6 1.8 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIK51268.1 - 0.095 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK51268.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIK51268.1 - 0.15 11.2 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KIK51268.1 - 0.31 11.6 1.2 0.41 11.2 1.2 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK51269.1 - 1.1e-23 83.0 11.2 1.1e-10 41.9 0.6 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51269.1 - 2.2e-10 40.7 0.0 0.0038 17.5 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51269.1 - 2e-05 23.7 0.8 0.2 10.6 0.0 3.0 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51269.1 - 0.00028 20.7 0.1 0.76 9.8 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK51269.1 - 0.0023 17.3 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KIK51269.1 - 0.0045 15.7 0.5 0.71 8.4 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ PF01011.21 KIK51269.1 - 0.015 15.2 0.1 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat rOmpB PF12334.8 KIK51269.1 - 0.019 14.4 3.4 8.8 5.7 0.1 3.0 1 1 0 3 3 3 0 Rickettsia outer membrane protein B Cuticle_4 PF15955.5 KIK51269.1 - 0.046 14.4 0.0 4.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Cuticle protein WD40_3 PF15911.5 KIK51269.1 - 0.13 12.3 1.0 27 4.9 0.0 3.2 3 1 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KIK51269.1 - 0.65 10.6 4.0 22 5.7 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain Mg_trans_NIPA PF05653.14 KIK51270.1 - 3.2e-81 272.7 31.5 4.3e-81 272.3 31.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIK51270.1 - 3e-07 30.7 7.1 3e-07 30.7 7.1 3.9 2 2 1 3 3 3 2 EamA-like transporter family Spem1 PF15670.5 KIK51271.1 - 0.18 11.3 2.0 0.31 10.6 2.0 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 VPS13 PF16908.5 KIK51274.1 - 0.0006 19.7 0.7 0.0006 19.7 0.7 2.2 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal EF-hand_1 PF00036.32 KIK51274.1 - 0.053 13.1 0.0 0.21 11.2 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KIK51274.1 - 0.1 12.6 0.0 0.45 10.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Methyltransf_23 PF13489.6 KIK51275.1 - 3.6e-15 56.2 0.0 4.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK51275.1 - 8.9e-12 45.1 0.0 7.9e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK51275.1 - 1.9e-11 44.5 0.0 3.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK51275.1 - 3.2e-10 40.6 0.0 1.2e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK51275.1 - 1.2e-09 38.8 0.0 4e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK51275.1 - 0.00014 21.3 0.0 0.00038 19.8 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIK51275.1 - 0.00077 19.1 0.0 0.0031 17.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIK51275.1 - 0.0017 17.7 0.0 0.0091 15.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KIK51275.1 - 0.0097 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DREV PF05219.12 KIK51275.1 - 0.03 13.4 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 KIK51275.1 - 0.054 12.9 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KIK51275.1 - 0.058 13.5 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KIK51275.1 - 0.11 11.9 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_29 PF03141.16 KIK51275.1 - 0.2 10.2 0.1 1.6 7.2 0.1 2.0 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fungal_trans PF04082.18 KIK51276.1 - 1e-30 106.7 0.0 2.2e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK51276.1 - 0.001 19.2 5.9 0.0018 18.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KIK51276.1 - 0.18 10.2 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Epimerase PF01370.21 KIK51277.1 - 4.9e-20 72.0 0.0 7.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK51277.1 - 5.8e-17 61.6 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK51277.1 - 1.3e-09 37.7 0.2 2.4e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK51277.1 - 4.5e-09 36.2 0.0 2e-07 30.8 0.0 2.5 2 2 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK51277.1 - 6e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK51277.1 - 0.00016 21.3 0.1 0.00027 20.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Cons_hypoth95 PF03602.15 KIK51277.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 KR PF08659.10 KIK51277.1 - 0.075 12.9 0.1 0.35 10.8 0.1 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KIK51277.1 - 0.12 11.9 0.1 0.24 10.8 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase EHN PF06441.12 KIK51278.1 - 1.3e-20 73.7 0.0 2.2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK51278.1 - 1.7e-15 57.4 0.0 2.3e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK51278.1 - 0.0018 18.9 0.3 0.0032 18.1 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family EppA_BapA PF07268.11 KIK51279.1 - 0.082 12.8 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Ca_chan_IQ PF08763.11 KIK51279.1 - 0.11 12.8 0.2 4.7 7.5 0.0 2.4 1 1 1 2 2 2 0 Voltage gated calcium channel IQ domain THEG4 PF15834.5 KIK51280.1 - 0.019 14.9 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Testis highly expressed protein 4 DUF262 PF03235.14 KIK51281.1 - 4.6e-18 66.2 0.1 7.8e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 Beta-lactamase PF00144.24 KIK51282.1 - 6.3e-32 111.1 0.3 1.4e-31 110.0 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase Epimerase PF01370.21 KIK51284.1 - 3.9e-23 82.2 0.0 5.6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK51284.1 - 1.5e-18 66.8 0.0 2.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK51284.1 - 2e-13 50.5 0.2 3.5e-12 46.4 0.2 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK51284.1 - 1.1e-11 44.4 0.0 1.4e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KIK51284.1 - 1e-07 32.1 0.1 1.8e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIK51284.1 - 5.4e-06 25.8 0.0 8.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK51284.1 - 2.2e-05 24.1 0.2 3.7e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK51284.1 - 0.0095 15.4 0.4 0.02 14.4 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Gamma_PGA_hydro PF05908.11 KIK51284.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase KR PF08659.10 KIK51284.1 - 0.03 14.2 0.2 0.11 12.4 0.2 1.8 1 1 0 1 1 1 0 KR domain ATP-synt PF00231.19 KIK51287.1 - 9.9e-10 38.6 0.0 1.2e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase RdRP_5 PF07925.11 KIK51287.1 - 0.051 11.0 0.2 0.061 10.7 0.2 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Epimerase PF01370.21 KIK51291.1 - 1e-22 80.8 0.0 1.4e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK51291.1 - 1.6e-17 63.4 0.0 2.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK51291.1 - 3.3e-12 46.4 0.0 2.2e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK51291.1 - 3.6e-12 46.0 0.0 5.7e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KIK51291.1 - 1.9e-08 34.4 0.0 3.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIK51291.1 - 2e-05 23.9 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK51291.1 - 2.3e-05 24.1 0.1 4.3e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KIK51291.1 - 0.0096 15.8 0.2 0.049 13.5 0.2 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KIK51291.1 - 0.013 14.9 0.2 0.026 14.0 0.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Gamma_PGA_hydro PF05908.11 KIK51291.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase DUF1622 PF07784.11 KIK51291.1 - 0.049 13.5 0.1 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1622) NAD_binding_9 PF13454.6 KIK51292.1 - 0.01 15.8 0.3 1.7 8.6 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK51292.1 - 0.012 15.8 0.0 0.09 13.0 0.0 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK51292.1 - 0.024 14.0 0.1 0.079 12.3 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KIK51292.1 - 0.032 13.5 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK51292.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KIK51292.1 - 0.24 11.4 0.0 0.62 10.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.17 KIK51294.1 - 4.1e-36 124.7 6.7 1.5e-35 122.8 6.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 EHN PF06441.12 KIK51295.1 - 4.8e-20 71.9 0.0 7.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK51295.1 - 6.3e-18 65.4 0.0 1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK51295.1 - 0.00087 19.9 1.5 0.0019 18.8 1.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF262 PF03235.14 KIK51296.1 - 8.5e-17 62.1 0.1 1.3e-16 61.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 G-alpha PF00503.20 KIK51297.1 - 5.3e-78 262.6 0.2 6.1e-78 262.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK51297.1 - 0.00062 19.3 0.1 0.0013 18.2 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family PHD PF00628.29 KIK51298.1 - 1.1e-08 34.8 4.9 1.9e-08 34.1 4.9 1.4 1 0 0 1 1 1 1 PHD-finger DUF3619 PF12279.8 KIK51298.1 - 0.27 11.6 0.9 0.48 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) PHD_2 PF13831.6 KIK51298.1 - 7.3 6.2 5.7 13 5.5 5.7 1.4 1 0 0 1 1 1 0 PHD-finger Plavaka PF18759.1 KIK51303.1 - 1.8e-11 43.8 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase KfrA_N PF11740.8 KIK51303.1 - 0.12 13.1 0.0 0.61 10.8 0.0 2.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term SDA1 PF05285.12 KIK51304.1 - 0.00031 20.3 11.5 0.00037 20.0 11.5 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 KIK51304.1 - 0.0028 16.0 9.0 0.0033 15.8 9.0 1.1 1 0 0 1 1 1 1 CDC45-like protein TRAP_alpha PF03896.16 KIK51304.1 - 0.042 13.0 8.9 0.066 12.4 8.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.13 KIK51304.1 - 0.048 12.4 6.8 0.066 12.0 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 KIK51304.1 - 0.089 12.0 0.2 0.083 12.1 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 KIK51304.1 - 0.3 9.8 6.2 0.43 9.3 6.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Roughex PF06020.11 KIK51304.1 - 0.32 10.1 10.5 0.51 9.4 10.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SAPS PF04499.15 KIK51304.1 - 0.39 9.5 5.5 0.5 9.1 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ORC_WH_C PF18137.1 KIK51304.1 - 0.56 10.3 9.8 1.1 9.3 9.8 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SpoIIP PF07454.11 KIK51304.1 - 1.9 7.8 9.6 3 7.2 9.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 KIK51304.1 - 2.5 6.2 22.7 3.4 5.8 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 KIK51304.1 - 8.3 6.7 17.2 14 5.9 17.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 KIK51304.1 - 8.5 6.3 15.1 18 5.2 15.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NACHT PF05729.12 KIK51305.1 - 6.6e-11 42.4 0.1 9.4e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK51305.1 - 1.8e-06 28.4 0.0 3.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK51305.1 - 0.00024 20.4 0.9 0.00047 19.4 0.9 1.5 1 1 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KIK51305.1 - 0.00031 20.8 0.0 0.00046 20.2 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK51305.1 - 0.00041 20.8 0.0 0.001 19.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIK51305.1 - 0.00042 19.8 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein APS_kinase PF01583.20 KIK51305.1 - 0.00046 20.1 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Glycos_transf_N PF04413.16 KIK51305.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) AAA_22 PF13401.6 KIK51305.1 - 0.0022 18.3 0.0 0.0053 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK51305.1 - 0.0082 16.7 0.1 0.046 14.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KIK51305.1 - 0.011 15.4 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase RNA_helicase PF00910.22 KIK51305.1 - 0.014 15.8 0.1 0.9 10.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 KIK51305.1 - 0.027 13.7 0.2 0.052 12.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KIK51305.1 - 0.055 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase PIF1 PF05970.14 KIK51305.1 - 0.071 12.3 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.18 KIK51305.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIK51305.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK51305.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK51308.1 - 6.3e-125 403.4 29.5 3.9e-11 43.3 0.0 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51308.1 - 4.4e-37 126.3 6.5 0.014 15.7 0.0 11.0 2 2 9 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51308.1 - 2.4e-20 73.2 5.5 0.0002 21.3 0.1 6.0 2 1 5 7 7 7 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK51308.1 - 4.8e-18 65.1 16.1 0.1 11.2 0.0 10.3 6 4 4 11 11 11 6 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK51308.1 - 6.7e-17 61.8 4.6 0.2 10.9 0.0 9.2 7 2 1 9 9 9 4 WD40-like domain Ge1_WD40 PF16529.5 KIK51308.1 - 4.7e-16 58.7 7.0 0.87 8.5 0.0 10.2 1 1 7 10 10 10 3 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK51308.1 - 1.7e-11 43.9 18.4 1.5 8.8 0.0 9.7 11 0 0 11 11 9 2 Nitrous oxide reductase propeller repeat PD40 PF07676.12 KIK51308.1 - 2.4e-11 43.2 9.6 1.8 8.6 0.0 10.6 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat NHL PF01436.21 KIK51308.1 - 2e-06 27.5 8.7 57 4.0 0.0 8.3 8 0 0 8 8 8 0 NHL repeat Cuticle_4 PF15955.5 KIK51308.1 - 9e-06 26.3 1.8 42 4.9 0.0 7.6 8 2 0 8 8 7 0 Cuticle protein Str_synth PF03088.16 KIK51308.1 - 9.9e-06 25.6 0.0 9 6.5 0.0 5.8 5 2 1 6 6 6 0 Strictosidine synthase SdiA-regulated PF06977.11 KIK51308.1 - 1.9e-05 24.1 0.0 4.4 6.4 0.0 4.6 3 2 2 5 5 5 2 SdiA-regulated COPI_C PF06957.11 KIK51308.1 - 0.00013 20.9 0.0 10 4.8 0.0 5.0 1 1 4 6 6 6 0 Coatomer (COPI) alpha subunit C-terminus DsbC_N PF10411.9 KIK51308.1 - 0.00037 19.9 7.4 98 2.5 0.0 8.0 8 0 0 8 8 8 0 Disulfide bond isomerase protein N-terminus PQQ_3 PF13570.6 KIK51308.1 - 0.001 19.5 30.5 6.9 7.3 0.1 9.0 3 3 7 10 10 10 1 PQQ-like domain HPS3_N PF14761.6 KIK51308.1 - 0.0014 18.2 0.4 2.5 7.6 0.0 4.6 4 2 2 6 6 6 1 Hermansky-Pudlak syndrome 3 DUF4072 PF13284.6 KIK51308.1 - 0.015 15.7 0.0 24 5.5 0.0 5.1 7 0 0 7 7 6 0 Domain of unknown function (DUF4072) Imm17 PF15562.6 KIK51308.1 - 0.039 13.8 0.0 75 3.3 0.0 4.8 8 0 0 8 8 5 0 Immunity protein 17 LRR_10 PF18805.1 KIK51308.1 - 0.05 13.3 17.0 23 4.7 0.1 8.2 7 3 2 10 10 10 0 Leucine-rich repeat Coatomer_WDAD PF04053.14 KIK51308.1 - 0.054 12.5 9.6 9.5 5.1 1.2 4.4 2 2 3 5 5 5 0 Coatomer WD associated region zf-LYAR PF08790.11 KIK51308.1 - 0.068 13.1 0.2 55 3.8 0.0 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Frtz PF11768.8 KIK51308.1 - 0.1 10.9 0.0 58 1.8 0.0 4.5 2 2 5 7 7 7 0 WD repeat-containing and planar cell polarity effector protein Fritz WW_like PF17890.1 KIK51308.1 - 0.3 11.2 17.3 1.9 8.6 0.1 7.3 9 0 0 9 9 9 0 Peptidoglycan hydrolase LytB WW-like domain Proteasome_A_N PF10584.9 KIK51308.1 - 7.6 6.3 19.1 56 3.5 0.1 8.7 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature APS_kinase PF01583.20 KIK51309.1 - 0.00047 20.1 0.1 0.00068 19.6 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 KIK51309.1 - 0.0015 18.9 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK51309.1 - 0.0029 17.5 0.1 0.0045 16.9 0.1 1.3 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK51309.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KIK51309.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KIK51309.1 - 0.029 13.6 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KIK51309.1 - 0.034 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 KIK51309.1 - 0.037 13.8 0.2 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KIK51309.1 - 0.037 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK51309.1 - 0.053 13.8 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 KIK51309.1 - 0.074 12.7 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_18 PF13238.6 KIK51309.1 - 0.075 13.6 0.3 0.14 12.7 0.1 1.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIK51309.1 - 0.082 12.6 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIK51309.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KIK51309.1 - 0.16 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK51309.1 - 0.16 11.4 0.1 0.3 10.5 0.1 1.4 1 1 0 1 1 1 0 PhoH-like protein ATP-synt_G PF04718.15 KIK51310.1 - 0.00066 20.5 0.0 0.0021 18.8 0.0 1.8 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit AMP-binding PF00501.28 KIK51311.1 - 2.5e-74 250.4 0.0 5.1e-74 249.4 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KIK51311.1 - 2e-25 89.4 0.0 8.1e-17 61.0 0.0 3.0 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KIK51311.1 - 5.8e-09 36.2 0.1 1.7e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Dimer_Tnp_hAT PF05699.14 KIK51315.1 - 5.1e-15 55.0 0.0 6.9e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Popeye PF04831.13 KIK51318.1 - 0.033 14.4 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Popeye protein conserved region RSN1_7TM PF02714.15 KIK51319.1 - 0.04 13.2 0.8 0.045 13.1 0.8 1.1 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate DUF570 PF04489.13 KIK51320.1 - 0.034 12.8 0.0 0.037 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF570) DUF308 PF03729.13 KIK51324.1 - 0.1 13.0 2.2 0.14 12.5 2.2 1.3 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Popeye PF04831.13 KIK51327.1 - 0.39 10.9 2.1 1.2 9.2 2.1 1.9 1 0 0 1 1 1 0 Popeye protein conserved region FTSW_RODA_SPOVE PF01098.19 KIK51329.1 - 0.17 10.8 1.2 4.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Cell cycle protein Popeye PF04831.13 KIK51330.1 - 0.31 11.2 0.1 0.31 11.2 0.1 1.4 2 0 0 2 2 2 0 Popeye protein conserved region ADH_zinc_N PF00107.26 KIK51332.1 - 8e-12 45.3 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK51332.1 - 8.2e-11 43.1 0.0 1.9e-10 41.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK51332.1 - 2.2e-06 27.5 0.5 2.5e-05 24.1 0.4 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KIK51332.1 - 0.039 13.8 0.2 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KIK51332.1 - 0.17 11.3 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GPI-anchored PF10342.9 KIK51334.1 - 0.00025 21.7 0.3 0.00025 21.7 0.3 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TPX2 PF06886.11 KIK51336.1 - 1.8e-12 47.3 18.4 1.8e-12 47.3 18.4 2.4 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) LEM PF03020.15 KIK51336.1 - 0.019 14.6 0.2 0.044 13.4 0.2 1.6 1 0 0 1 1 1 0 LEM domain zf-H2C2_2 PF13465.6 KIK51337.1 - 0.0002 21.6 0.2 0.0002 21.6 0.2 2.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK51337.1 - 0.00034 20.9 11.6 0.0082 16.6 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KIK51337.1 - 0.0021 18.4 4.5 0.017 15.5 0.3 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK51337.1 - 0.0029 18.3 10.2 0.028 15.2 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK51337.1 - 0.22 11.9 0.2 0.22 11.9 0.2 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Gemini_AC4_5 PF04807.12 KIK51341.1 - 0.2 11.3 0.1 0.37 10.5 0.1 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region SLC12 PF03522.15 KIK51341.1 - 9.7 5.1 9.1 17 4.3 9.1 1.4 1 0 0 1 1 1 0 Solute carrier family 12 F-box PF00646.33 KIK51342.1 - 9.4e-05 22.2 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK51342.1 - 0.00056 19.7 0.2 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like Abhydrolase_3 PF07859.13 KIK51344.1 - 1.7e-19 70.6 0.0 2.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK51344.1 - 1.5e-12 47.1 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK51344.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF308 PF03729.13 KIK51346.1 - 0.44 10.9 5.0 0.7 10.3 4.2 1.7 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) p450 PF00067.22 KIK51348.1 - 6e-73 246.2 0.0 8.7e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lzipper-MIP1 PF14389.6 KIK51349.1 - 0.0072 16.6 2.2 0.0072 16.6 2.2 3.3 2 1 2 4 4 4 1 Leucine-zipper of ternary complex factor MIP1 JIP_LZII PF16471.5 KIK51349.1 - 0.68 10.1 7.9 8.6 6.6 0.1 3.6 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.9 KIK51349.1 - 0.81 9.7 24.5 0.61 10.1 5.0 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 KIK51349.1 - 1.5 9.1 22.8 0.36 11.1 4.4 4.0 3 1 1 4 4 4 0 Tho complex subunit 7 KIP1 PF07765.12 KIK51349.1 - 4.3 7.5 9.6 0.14 12.3 1.6 2.6 3 0 0 3 3 3 0 KIP1-like protein Fez1 PF06818.15 KIK51350.1 - 0.2 12.1 21.6 0.14 12.6 17.2 2.4 1 1 1 2 2 2 0 Fez1 SOGA PF11365.8 KIK51350.1 - 2.1 9.5 11.8 0.25 12.5 4.2 3.1 1 1 2 3 3 3 0 Protein SOGA Mod_r PF07200.13 KIK51350.1 - 2.2 8.4 16.8 20 5.3 15.5 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein KASH_CCD PF14662.6 KIK51350.1 - 3.8 7.3 20.3 1.3 8.8 4.6 2.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 KIK51350.1 - 8.2 5.6 6.1 5.2 6.2 4.2 1.6 1 1 0 1 1 1 0 TMPIT-like protein Ras PF00071.22 KIK51352.1 - 5.9e-50 169.0 0.0 8.6e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK51352.1 - 7.7e-31 106.8 0.0 1.1e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK51352.1 - 1.4e-11 44.2 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK51352.1 - 8.1e-06 25.5 0.0 6.6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK51352.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK51352.1 - 0.099 12.5 0.0 7.4 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Cadherin_3 PF16184.5 KIK51355.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Cadherin-like CHAT PF12770.7 KIK51356.1 - 3e-41 141.7 0.4 5.8e-41 140.8 0.4 1.5 1 0 0 1 1 1 1 CHAT domain TPR_2 PF07719.17 KIK51356.1 - 0.00011 22.0 0.3 12 6.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51356.1 - 0.00017 21.6 0.2 27 5.3 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK51356.1 - 0.0022 17.8 10.2 0.035 14.0 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat IPK PF03770.16 KIK51356.1 - 0.023 14.6 0.0 0.076 12.9 0.0 2.0 3 0 0 3 3 3 0 Inositol polyphosphate kinase YacG PF03884.14 KIK51356.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG TPR_12 PF13424.6 KIK51356.1 - 0.15 12.4 12.0 8.1 6.8 0.1 5.7 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK51356.1 - 0.16 12.8 11.9 0.97 10.4 0.1 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK51357.1 - 0.0031 17.5 10.1 0.074 13.2 0.4 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK51357.1 - 0.052 13.4 4.2 2.9 7.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK51357.1 - 0.83 9.4 10.3 0.21 11.3 0.3 3.9 4 0 0 4 4 4 0 TPR repeat DUF2070 PF09843.9 KIK51358.1 - 3.1 6.0 14.7 0.44 8.8 10.9 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) SP_C-Propep PF08999.10 KIK51359.1 - 0.11 12.3 0.5 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide GET2 PF08690.10 KIK51359.1 - 0.16 11.7 2.8 0.3 10.7 2.8 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Glyco_transf_8 PF01501.20 KIK51360.1 - 1.2e-13 51.2 0.0 3.7e-12 46.4 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 SnoaL PF07366.12 KIK51361.1 - 0.0052 16.6 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SKG6 PF08693.10 KIK51362.1 - 0.0025 17.2 0.5 0.0062 15.9 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KIK51362.1 - 0.014 15.9 0.8 0.014 15.9 0.8 2.8 3 2 0 3 3 3 0 Alphavirus glycoprotein J TMEM51 PF15345.6 KIK51362.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Yip1 PF04893.17 KIK51362.1 - 2 8.1 8.2 0.18 11.5 0.4 2.3 1 1 1 2 2 2 0 Yip1 domain Methyltransf_2 PF00891.18 KIK51363.1 - 8.6e-22 77.5 0.0 3.4e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 KIK51363.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KIK51363.1 - 0.057 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK51363.1 - 0.098 13.4 0.0 0.22 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIK51363.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KIK51364.1 - 7.1e-23 81.0 0.0 1.7e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 KIK51364.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KIK51364.1 - 0.039 14.7 0.0 0.11 13.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK51364.1 - 0.081 13.6 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIK51364.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PC-Esterase PF13839.6 KIK51365.1 - 7.8e-05 22.6 0.0 0.0062 16.3 0.0 2.3 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MMR_HSR1 PF01926.23 KIK51367.1 - 2.3e-10 40.5 3.4 7.1e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK51367.1 - 2.6e-08 33.5 0.1 2.6e-08 33.5 0.1 2.1 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KIK51367.1 - 4.6e-07 30.1 10.3 0.01 15.9 0.1 3.4 2 2 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KIK51367.1 - 3.6e-06 27.0 2.8 1.8e-05 24.7 0.1 2.7 2 1 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KIK51367.1 - 3.8e-05 24.3 8.9 0.018 15.5 5.7 2.2 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KIK51367.1 - 0.0023 18.5 9.9 0.35 11.4 9.9 2.4 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 KIK51367.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 KIK51367.1 - 0.0032 16.6 0.5 0.0077 15.3 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KIK51367.1 - 0.0042 16.5 0.9 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family YtxH PF12732.7 KIK51367.1 - 0.0043 17.6 4.1 0.0087 16.6 3.5 1.9 1 1 0 1 1 1 1 YtxH-like protein TubC_N PF18563.1 KIK51367.1 - 0.013 15.5 0.3 0.052 13.5 0.3 2.1 1 0 0 1 1 1 0 TubC N-terminal docking domain AAA_29 PF13555.6 KIK51367.1 - 0.015 15.0 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain BCAS2 PF05700.11 KIK51367.1 - 0.023 14.4 11.8 0.034 13.8 11.8 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Golgin_A5 PF09787.9 KIK51367.1 - 0.048 13.1 15.5 0.067 12.7 15.3 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 GBP PF02263.19 KIK51367.1 - 0.058 12.6 1.4 0.061 12.6 0.0 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain DUF87 PF01935.17 KIK51367.1 - 0.062 13.4 7.6 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain BLOC1_2 PF10046.9 KIK51367.1 - 0.068 13.5 5.7 0.13 12.5 5.7 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cluap1 PF10234.9 KIK51367.1 - 0.094 12.1 9.3 0.13 11.7 9.3 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 HCV_NS2 PF01538.18 KIK51367.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 Spc7 PF08317.11 KIK51367.1 - 0.2 10.5 15.8 0.3 9.9 15.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KIK51367.1 - 0.26 11.5 10.7 0.72 10.0 4.0 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KIK51367.1 - 0.26 10.6 8.6 0.45 9.8 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP_bind_1 PF03029.17 KIK51367.1 - 0.29 10.9 4.6 1.4 8.7 0.2 3.2 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Fzo_mitofusin PF04799.13 KIK51367.1 - 0.42 10.1 6.5 0.44 10.1 4.2 1.7 1 1 1 2 2 2 0 fzo-like conserved region TPR_MLP1_2 PF07926.12 KIK51367.1 - 0.47 10.5 15.2 1.1 9.4 14.8 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Presenilin PF01080.17 KIK51367.1 - 0.69 8.6 6.7 0.86 8.3 6.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3450 PF11932.8 KIK51367.1 - 0.7 9.1 11.0 1 8.6 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KIK51367.1 - 1 9.4 6.6 2.5 8.1 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_33 PF13671.6 KIK51367.1 - 1.2 9.3 5.6 0.53 10.4 0.2 2.7 2 2 0 2 2 2 0 AAA domain ISG65-75 PF11727.8 KIK51367.1 - 1.2 8.3 9.1 1.9 7.7 9.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF948 PF06103.11 KIK51367.1 - 1.4 9.2 3.6 8.3 6.7 1.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PIN_8 PF18476.1 KIK51367.1 - 1.8 8.3 11.4 0.77 9.6 8.5 1.7 2 0 0 2 2 2 0 PIN like domain MutS_III PF05192.18 KIK51367.1 - 4 7.6 6.8 6.5 6.9 6.8 1.3 1 0 0 1 1 1 0 MutS domain III HAUS6_N PF14661.6 KIK51367.1 - 4.2 6.9 9.6 6.5 6.3 9.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Syntaxin-6_N PF09177.11 KIK51367.1 - 4.8 7.8 10.0 3.4 8.3 7.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.14 KIK51367.1 - 5.1 7.4 18.8 10 6.5 18.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 KIK51367.1 - 7.8 5.6 7.4 11 5.1 7.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein MMR_HSR1 PF01926.23 KIK51368.1 - 3.4e-08 33.6 0.1 2.1e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK51368.1 - 2.5e-06 27.6 1.6 0.0039 17.3 0.3 3.0 2 1 1 3 3 3 2 Dynamin family AAA_18 PF13238.6 KIK51368.1 - 0.00024 21.7 0.0 0.024 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 KIK51368.1 - 0.00048 19.7 3.6 0.016 14.7 0.0 3.0 2 1 1 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 KIK51368.1 - 0.00079 19.9 0.1 0.0039 17.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KIK51368.1 - 0.0015 19.1 1.0 0.04 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIK51368.1 - 0.0016 18.4 0.0 0.0046 16.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KIK51368.1 - 0.0025 17.2 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 KIK51368.1 - 0.0038 17.5 0.0 0.014 15.7 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK51368.1 - 0.0068 16.8 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK51368.1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KIK51368.1 - 0.0092 16.2 0.1 0.14 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KIK51368.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KIK51368.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK51368.1 - 0.031 14.2 1.5 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 NTPase IIGP PF05049.13 KIK51368.1 - 0.046 12.8 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.17 KIK51368.1 - 0.054 13.3 1.4 0.096 12.5 0.1 2.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PRK PF00485.18 KIK51368.1 - 0.094 12.4 0.1 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 KIK51368.1 - 0.095 13.1 0.1 0.3 11.5 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KIK51368.1 - 0.11 12.8 0.0 0.48 10.7 0.0 2.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KIK51368.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK51368.1 - 0.12 11.5 0.4 0.73 9.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain GTP_EFTU PF00009.27 KIK51368.1 - 0.13 11.8 0.0 17 4.9 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK51369.1 - 1.1e-05 25.5 0.5 2.9e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK51369.1 - 6.5e-05 22.4 0.2 6.5e-05 22.4 0.2 1.6 2 0 0 2 2 2 1 AIG1 family Troponin PF00992.20 KIK51369.1 - 0.0012 19.1 5.2 0.0012 19.1 5.2 1.6 2 0 0 2 2 1 1 Troponin FeoB_N PF02421.18 KIK51369.1 - 0.0032 17.0 0.1 0.0064 16.0 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B HAUS-augmin3 PF14932.6 KIK51369.1 - 0.0091 15.6 5.7 0.016 14.8 5.7 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 LXG PF04740.12 KIK51369.1 - 0.026 14.2 0.5 0.047 13.4 0.5 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DegS PF05384.11 KIK51369.1 - 0.042 13.3 2.2 0.086 12.3 2.2 1.4 1 0 0 1 1 1 0 Sensor protein DegS CREPT PF16566.5 KIK51369.1 - 0.094 12.9 1.8 0.12 12.5 0.8 1.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour OmpH PF03938.14 KIK51369.1 - 0.15 12.4 1.0 6.4 7.1 1.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fmp27_WPPW PF10359.9 KIK51369.1 - 0.15 10.8 3.3 0.082 11.8 1.5 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Med9 PF07544.13 KIK51369.1 - 0.16 12.1 1.2 0.37 10.9 0.6 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RP-C_C PF11800.8 KIK51369.1 - 0.16 12.1 2.3 0.26 11.4 2.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Dynamin_N PF00350.23 KIK51369.1 - 0.21 11.6 8.1 0.48 10.4 0.1 3.3 2 1 1 3 3 3 0 Dynamin family YtxH PF12732.7 KIK51369.1 - 0.25 11.9 0.8 0.94 10.1 0.3 2.1 2 0 0 2 2 2 0 YtxH-like protein SRPRB PF09439.10 KIK51369.1 - 0.29 10.5 2.1 0.33 10.4 0.1 2.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit YabA PF06156.13 KIK51369.1 - 0.32 11.6 2.4 1.2 9.8 1.4 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Apolipoprotein PF01442.18 KIK51369.1 - 0.37 10.6 7.8 1.8 8.4 7.8 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AA_permease PF00324.21 KIK51370.1 - 2.4e-130 435.4 35.4 2.9e-130 435.0 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK51370.1 - 1.3e-35 123.1 41.4 1.5e-35 122.8 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease ABM PF03992.16 KIK51372.1 - 0.0052 16.9 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase F-box-like PF12937.7 KIK51373.1 - 5.2e-09 35.9 2.0 1.2e-08 34.7 2.0 1.7 1 0 0 1 1 1 1 F-box-like DEAD PF00270.29 KIK51374.1 - 9.7e-45 152.5 1.1 9.7e-45 152.5 1.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK51374.1 - 1.6e-33 115.4 0.3 1.8e-31 108.7 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK51374.1 - 2e-06 27.9 0.0 3.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK51374.1 - 5.9e-05 23.4 1.3 0.0012 19.2 0.5 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK51374.1 - 0.00044 20.0 0.1 0.0008 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KIK51374.1 - 0.06 13.3 0.1 0.24 11.3 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 KIK51374.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KIK51374.1 - 0.095 13.0 0.8 0.46 10.8 0.3 2.4 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 KIK51374.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase DSPc PF00782.20 KIK51375.1 - 1.3e-25 89.7 0.0 1.4e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK51375.1 - 9.4e-05 22.7 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIK51375.1 - 0.051 13.1 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase G-patch PF01585.23 KIK51375.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 G-patch domain YibE_F PF07907.11 KIK51376.1 - 0.003 17.1 7.1 0.003 17.1 7.1 2.1 2 0 0 2 2 2 2 YibE/F-like protein zf-C2H2_4 PF13894.6 KIK51377.1 - 2.2e-06 28.0 6.9 0.013 16.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK51377.1 - 1.5e-05 25.1 9.3 0.017 15.6 4.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KIK51377.1 - 2.5e-05 24.5 3.3 0.01 16.2 0.6 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KIK51377.1 - 5.6e-05 23.4 0.3 5.6e-05 23.4 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK51377.1 - 0.0019 18.5 10.3 0.0041 17.4 0.4 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding E1-E2_ATPase PF00122.20 KIK51380.1 - 0.16 11.5 2.4 7.2 6.1 0.2 2.3 2 0 0 2 2 2 0 E1-E2 ATPase Popeye PF04831.13 KIK51380.1 - 0.94 9.6 4.3 0.24 11.6 0.3 2.0 2 0 0 2 2 2 0 Popeye protein conserved region Glycos_transf_2 PF00535.26 KIK51381.1 - 1.2e-19 70.8 0.0 1.7e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIK51381.1 - 0.0012 18.8 0.1 0.36 10.7 0.0 2.4 2 1 0 2 2 2 2 Glycosyltransferase like family 2 HlyIII PF03006.20 KIK51384.1 - 1.2e-51 175.6 20.6 1.4e-51 175.4 20.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Alpha-amylase PF00128.24 KIK51385.1 - 1.3e-12 47.9 0.0 5.2e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIK51385.1 - 2.3e-08 34.4 0.0 6.7e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Ricin_B_lectin PF00652.22 KIK51386.1 - 8.5e-25 87.5 7.8 1e-24 87.2 7.8 1.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIK51386.1 - 3.8e-23 82.0 22.5 2.9e-09 37.5 0.3 2.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like ET PF01684.16 KIK51386.1 - 0.025 14.9 3.1 2.4 8.6 0.2 2.4 1 1 0 2 2 2 0 ET module PSP94 PF05825.11 KIK51386.1 - 0.22 12.1 2.5 0.29 11.7 0.3 2.0 2 0 0 2 2 2 0 Beta-microseminoprotein (PSP-94) TPR_12 PF13424.6 KIK51387.1 - 1.3e-09 38.2 3.7 0.00028 21.1 0.9 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK51387.1 - 2.3e-05 24.2 3.5 0.31 11.3 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK51387.1 - 2.9e-05 23.4 1.5 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_1 PF00515.28 KIK51387.1 - 0.00067 19.4 3.0 4.1 7.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51387.1 - 0.01 16.0 2.4 16 6.0 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat NPV_P10 PF05531.12 KIK51387.1 - 0.095 13.2 0.0 5.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_10 PF13374.6 KIK51387.1 - 0.11 12.5 6.4 0.46 10.4 0.0 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK51387.1 - 0.23 12.0 4.3 4.8 7.8 1.9 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat GMC_oxred_C PF05199.13 KIK51389.1 - 0.13 12.7 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase F-box_5 PF18511.1 KIK51392.1 - 0.22 11.1 0.5 0.8 9.3 0.1 2.0 2 0 0 2 2 2 0 F-box Read-through PF16814.5 KIK51393.1 - 0.22 11.3 0.6 0.41 10.4 0.6 1.4 1 0 0 1 1 1 0 Read-through domain adh_short_C2 PF13561.6 KIK51398.1 - 4.8e-47 160.5 0.0 7.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK51398.1 - 2e-43 148.1 0.0 3.8e-43 147.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK51398.1 - 1.5e-07 31.5 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK51398.1 - 0.00018 21.4 0.3 0.00026 20.9 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KIK51398.1 - 0.0013 18.0 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK51398.1 - 0.017 14.6 0.0 5 6.5 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIK51398.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KIK51398.1 - 0.17 12.4 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Erp_C PF06780.11 KIK51398.1 - 0.24 11.4 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 Erp protein C-terminus CcmD PF04995.14 KIK51399.1 - 0.39 10.8 2.5 0.6 10.2 0.1 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Cupin_2 PF07883.11 KIK51400.1 - 3.6e-08 33.0 1.9 5.6e-08 32.4 0.6 1.9 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.22 KIK51400.1 - 0.0016 18.0 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 Cupin GTSE1_N PF15259.6 KIK51400.1 - 0.036 14.2 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 AMP-binding PF00501.28 KIK51401.1 - 5.5e-66 222.9 0.0 7.1e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK51401.1 - 1.5e-16 61.1 0.3 3.2e-16 60.0 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_4 PF13637.6 KIK51402.1 - 4e-21 75.1 7.1 1.6e-08 35.0 0.4 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK51402.1 - 4.1e-18 65.8 14.4 2e-11 44.3 3.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK51402.1 - 2e-12 46.9 10.4 0.0069 16.8 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KIK51402.1 - 4.6e-11 41.9 4.8 0.015 15.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK51402.1 - 2e-06 28.0 5.1 0.054 13.8 0.8 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 KIK51402.1 - 1.4 9.5 14.3 0.93 10.0 0.7 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) NACHT PF05729.12 KIK51403.1 - 0.028 14.3 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain NACHT PF05729.12 KIK51404.1 - 0.01 15.8 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIK51404.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KIK51404.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC HATPase_c PF02518.26 KIK51405.1 - 8.6e-22 77.8 0.0 2.4e-21 76.3 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK51405.1 - 4.9e-15 55.7 0.2 3e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KIK51405.1 - 1.3e-06 28.3 0.1 3.6e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KIK51405.1 - 0.13 12.2 0.1 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF2070 PF09843.9 KIK51405.1 - 2 6.6 5.9 3 6.0 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cupin_2 PF07883.11 KIK51407.1 - 0.0024 17.6 0.1 0.0031 17.2 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_2 PF07883.11 KIK51408.1 - 8.6e-08 31.8 0.3 2.3e-07 30.4 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KIK51408.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KIK51408.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.11 KIK51409.1 - 1.9e-05 24.3 0.1 6.6e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_2 PF07883.11 KIK51410.1 - 9.1e-08 31.7 0.2 1.7e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KIK51410.1 - 0.00058 19.5 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 Cupin Rhabdo_M2 PF04785.12 KIK51410.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Cupin_3 PF05899.12 KIK51410.1 - 0.037 13.7 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) F-box-like PF12937.7 KIK51411.1 - 6e-08 32.5 2.4 2.2e-07 30.7 2.4 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK51412.1 - 1.5e-07 31.2 3.6 1.5e-07 31.2 3.6 2.1 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KIK51412.1 - 0.088 12.7 5.0 3.2 7.7 0.2 2.8 3 1 0 3 3 3 0 F-box domain FAD_binding_3 PF01494.19 KIK51414.1 - 1.3e-20 74.0 0.0 6.8e-10 38.7 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK51414.1 - 7.6e-05 22.9 0.0 0.00045 20.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK51414.1 - 0.0018 17.2 0.0 0.038 12.8 0.0 2.5 2 1 1 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KIK51414.1 - 0.038 13.6 0.4 0.095 12.3 0.2 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK51414.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KIK51414.1 - 0.081 12.1 0.0 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-HC5HC2H_2 PF13832.6 KIK51415.1 - 1.9e-19 69.9 26.2 1.9e-19 69.8 4.0 4.3 2 1 1 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIK51415.1 - 7e-16 58.3 2.5 7e-16 58.3 2.5 4.5 3 1 1 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 KIK51415.1 - 6.1e-14 51.6 56.2 3.2e-08 33.4 10.4 5.8 6 0 0 6 6 6 3 PHD-finger BAH PF01426.18 KIK51415.1 - 5.4e-11 42.4 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 KIK51415.1 - 3e-05 23.5 30.4 3.8e-05 23.2 0.5 6.1 5 0 0 5 5 5 2 PHD-finger GATA PF00320.27 KIK51415.1 - 0.0011 18.6 9.9 0.0032 17.0 1.9 3.4 2 0 0 2 2 2 1 GATA zinc finger C1_1 PF00130.22 KIK51415.1 - 0.004 17.0 3.6 0.004 17.0 3.6 6.4 7 0 0 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) BCAS2 PF05700.11 KIK51415.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) SnoaL_2 PF12680.7 KIK51416.1 - 4.8e-09 36.8 0.0 6.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KIK51416.1 - 4e-07 30.2 0.0 4.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KIK51416.1 - 4.5e-05 23.3 0.0 5.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KIK51416.1 - 0.00014 22.2 0.0 0.00015 22.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KIK51416.1 - 0.046 14.0 0.0 0.058 13.7 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF3911 PF13050.6 KIK51416.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) adh_short PF00106.25 KIK51419.1 - 2.2e-19 69.7 0.1 2.1e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK51419.1 - 2.8e-14 53.3 0.1 3.4e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK51420.1 - 7e-25 87.6 0.2 8.7e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK51420.1 - 8.9e-18 64.7 0.3 1.1e-17 64.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK51420.1 - 1.7e-08 34.6 0.1 2.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK51420.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK51420.1 - 0.0019 18.1 0.7 0.002 18.0 0.7 1.3 1 1 0 1 1 1 1 NAD(P)H-binding MspA PF09203.11 KIK51420.1 - 0.037 13.9 0.4 0.075 12.9 0.4 1.4 1 0 0 1 1 1 0 MspA adh_short PF00106.25 KIK51421.1 - 2e-25 89.4 0.1 2.6e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK51421.1 - 4.1e-18 65.8 0.1 5.2e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIK51421.1 - 1.6e-05 24.8 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIK51421.1 - 3.3e-05 23.9 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK51421.1 - 0.0074 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-MYND PF01753.18 KIK51422.1 - 2.4e-10 40.3 8.2 6.2e-10 39.0 8.2 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK51422.1 - 0.028 14.7 10.5 0.028 14.7 10.5 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KIK51423.1 - 2.2e-10 40.4 8.5 2.2e-10 40.4 8.5 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIK51423.1 - 0.018 15.3 10.0 0.052 13.9 10.0 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KIK51423.1 - 0.67 10.1 8.1 0.075 13.1 3.6 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 adh_short PF00106.25 KIK51424.1 - 2.9e-24 85.6 0.0 3.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK51424.1 - 1.4e-17 64.1 0.1 1.8e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIK51424.1 - 9.7e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIK51424.1 - 0.00027 20.9 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK51424.1 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KIK51431.1 - 2.9e-36 125.1 53.1 1.1e-35 123.3 45.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KIK51431.1 - 0.0025 16.2 1.7 0.0025 16.2 1.7 3.7 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KIK51431.1 - 0.13 10.6 13.5 0.042 12.3 10.3 1.8 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3043 PF11241.8 KIK51431.1 - 0.26 11.3 0.7 0.79 9.7 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Fungal_trans PF04082.18 KIK51432.1 - 6.8e-10 38.4 2.2 1.6e-09 37.2 2.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain CDO_I PF05995.12 KIK51432.1 - 0.093 12.0 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Cysteine dioxygenase type I Stn1_C PF12659.7 KIK51432.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH Orthopox_B11R PF07033.11 KIK51432.1 - 0.23 11.3 0.0 0.48 10.3 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus B11R protein GMC_oxred_N PF00732.19 KIK51433.1 - 2.5e-72 243.8 0.0 3.1e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK51433.1 - 1.8e-32 112.9 0.1 2.8e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK51433.1 - 0.00059 20.0 0.3 0.0013 18.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK51433.1 - 0.0011 18.3 0.0 0.0069 15.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK51433.1 - 0.0034 16.5 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK51433.1 - 0.019 14.1 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KIK51433.1 - 0.033 13.8 0.2 0.2 11.2 0.2 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK51433.1 - 0.11 11.7 0.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KIK51433.1 - 0.18 12.1 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain KDZ PF18758.1 KIK51434.1 - 1.4e-31 109.9 0.2 1.5e-31 109.8 0.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TPR_20 PF14561.6 KIK51435.1 - 0.089 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat VWA PF00092.28 KIK51436.1 - 0.045 14.0 0.0 0.046 14.0 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4262 PF14081.6 KIK51436.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) p450 PF00067.22 KIK51438.1 - 5.1e-12 45.3 0.0 6.7e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 KIK51438.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Stirrup Methyltransf_25 PF13649.6 KIK51444.1 - 4.1e-05 24.2 0.0 0.00045 20.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK51444.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK51444.1 - 0.11 13.2 0.0 0.27 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain VWA PF00092.28 KIK51445.1 - 4.6e-08 33.5 0.0 6.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK51445.1 - 0.00044 20.9 0.0 0.0013 19.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIK51445.1 - 0.0048 16.9 0.0 0.032 14.2 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KIK51445.1 - 0.013 15.6 0.2 0.089 12.9 0.2 2.0 1 1 0 1 1 1 0 vWA found in TerF C terminus GMC_oxred_N PF00732.19 KIK51446.1 - 6.5e-65 219.4 0.0 8.4e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK51446.1 - 1.4e-33 116.4 0.0 2.5e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK51446.1 - 4e-06 26.2 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIK51446.1 - 2.4e-05 24.1 0.1 0.004 16.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK51446.1 - 7.1e-05 23.0 0.1 0.00018 21.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK51446.1 - 0.00015 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK51446.1 - 0.00052 19.4 0.2 0.23 10.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK51446.1 - 0.0022 17.3 0.2 0.0074 15.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK51446.1 - 0.015 14.5 0.8 0.045 13.0 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK51446.1 - 0.036 12.8 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FMO-like PF00743.19 KIK51447.1 - 7.7e-23 80.7 0.9 2.9e-20 72.2 1.1 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK51447.1 - 5.8e-19 68.5 0.0 5.7e-16 58.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK51447.1 - 3.2e-14 52.9 0.1 2.4e-10 40.1 0.1 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK51447.1 - 1.9e-12 47.0 0.4 2.1e-08 33.7 0.2 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK51447.1 - 3.8e-08 33.8 0.0 0.021 15.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK51447.1 - 9.1e-08 31.7 0.0 8.3e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KIK51447.1 - 2.1e-06 27.8 0.0 2.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK51447.1 - 1.9e-05 23.9 0.2 0.15 11.1 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 KIK51447.1 - 0.00031 19.6 0.1 0.13 10.9 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 KIK51447.1 - 0.00065 19.1 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KIK51447.1 - 0.00072 19.2 0.6 0.43 10.1 0.1 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase ASL_C2 PF14698.6 KIK51447.1 - 0.0028 18.3 0.0 0.0076 17.0 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal NAD_binding_9 PF13454.6 KIK51447.1 - 0.014 15.3 0.7 2.4 8.1 0.1 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIK51447.1 - 0.023 14.8 0.0 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KIK51447.1 - 0.035 13.3 0.0 0.085 12.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KIK51447.1 - 0.05 12.7 0.3 0.74 8.8 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-MYND PF01753.18 KIK51448.1 - 2.5e-11 43.5 11.8 5.2e-11 42.4 11.8 1.6 1 1 0 1 1 1 1 MYND finger Viral_helicase1 PF01443.18 KIK51449.1 - 0.17 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KIK51451.1 - 9.2e-07 28.3 0.2 9.2e-07 28.3 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK51451.1 - 3.7e-05 23.5 0.0 4.1e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KIK51451.1 - 0.001 18.1 0.0 0.0011 18.0 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIK51451.1 - 0.0029 18.0 0.0 0.0029 18.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK51451.1 - 0.0075 16.6 0.0 0.0084 16.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIK51451.1 - 0.018 15.1 0.1 0.021 14.9 0.1 1.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 KIK51451.1 - 0.07 12.2 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KIK51451.1 - 0.084 12.0 0.0 0.092 11.9 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain LpxK PF02606.14 KIK51451.1 - 0.085 11.9 0.0 0.097 11.7 0.0 1.0 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Guanylate_kin PF00625.21 KIK51451.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Guanylate kinase DUF815 PF05673.13 KIK51451.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 KIK51451.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.9 KIK51451.1 - 0.17 10.8 0.0 0.18 10.7 0.0 1.0 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Helicase_RecD PF05127.14 KIK51451.1 - 0.18 11.6 0.1 0.19 11.5 0.1 1.0 1 0 0 1 1 1 0 Helicase cobW PF02492.19 KIK51451.1 - 0.19 11.3 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SCRL PF06876.12 KIK51453.1 - 0.43 10.8 4.3 0.28 11.4 0.4 2.1 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Helitron_like_N PF14214.6 KIK51454.1 - 2.5e-20 73.5 0.0 2.9e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-MYND PF01753.18 KIK51458.1 - 1.1e-08 35.0 12.7 2.2e-08 34.0 12.7 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK51458.1 - 0.085 13.2 9.5 0.22 11.9 9.5 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 KIK51458.1 - 3 5.6 7.6 4.2 5.1 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-HIT PF04438.16 KIK51458.1 - 5.2 7.0 9.9 28 4.7 9.9 2.2 1 1 0 1 1 1 0 HIT zinc finger NAD_binding_4 PF07993.12 KIK51461.1 - 6.6e-32 110.7 0.0 9.8e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK51461.1 - 3.8e-23 81.8 0.0 6.1e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK51461.1 - 3.8e-07 29.8 0.0 7.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK51461.1 - 0.024 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 KIK51461.1 - 0.072 12.2 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.21 KIK51462.1 - 4.1e-10 39.5 0.0 3.2e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK51462.1 - 2.8e-09 37.1 0.0 4.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK51462.1 - 8.5e-06 26.0 0.1 1.4e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KIK51462.1 - 0.00023 20.8 0.2 0.00047 19.8 0.2 1.4 2 0 0 2 2 2 1 NmrA-like family NAD_binding_2 PF03446.15 KIK51462.1 - 0.00032 20.9 0.0 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 KIK51462.1 - 0.0013 18.2 0.1 0.0021 17.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KIK51462.1 - 0.0039 16.2 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 KIK51462.1 - 0.0087 15.4 0.3 0.012 14.9 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIK51462.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fibrillarin PF01269.17 KIK51462.1 - 0.033 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Shikimate_DH PF01488.20 KIK51462.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KIK51462.1 - 0.099 12.0 0.5 0.38 10.1 0.1 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KIK51462.1 - 0.099 12.0 0.1 0.37 10.1 0.0 1.9 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KIK51462.1 - 0.11 12.4 0.4 2.5 8.0 0.1 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KIK51464.1 - 3.6e-59 200.2 2.1 4.5e-59 199.9 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK51464.1 - 1.6e-44 151.7 2.7 1.9e-44 151.5 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK51464.1 - 1.5e-08 34.8 1.7 2.8e-08 33.9 1.7 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK51464.1 - 0.05 12.9 0.3 0.095 12.0 0.3 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dabb PF07876.12 KIK51465.1 - 1.8e-14 54.1 0.0 2e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldedh PF00171.22 KIK51466.1 - 0.016 13.7 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family PGA2 PF07543.12 KIK51467.1 - 0.015 15.3 2.4 0.024 14.6 2.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF1993 PF09351.10 KIK51467.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF2201_N PF13203.6 KIK51467.1 - 0.24 11.0 2.1 0.36 10.4 2.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DDE_3 PF13358.6 KIK51468.1 - 0.0032 17.2 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Fungal_trans PF04082.18 KIK51469.1 - 4.9e-09 35.6 1.0 7.8e-09 35.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAST_1 PF06743.15 KIK51469.1 - 0.087 12.8 0.0 0.68 9.9 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 p450 PF00067.22 KIK51470.1 - 1.6e-29 103.0 0.0 7.4e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 KIK51471.1 - 2.3e-24 86.0 66.9 5.2e-17 61.8 38.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.26 KIK51473.1 - 1.2e-76 257.7 0.0 2.6e-76 256.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK51473.1 - 2.1e-46 158.9 0.0 1.4e-41 143.0 0.0 2.6 3 0 0 3 3 3 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KIK51473.1 - 1.4e-34 118.6 0.1 3.7e-34 117.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KIK51473.1 - 2.7e-26 92.8 2.3 2.7e-26 92.8 2.3 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KIK51473.1 - 1.1e-23 83.3 5.1 6.2e-11 42.5 1.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KIK51473.1 - 3.5e-23 82.3 0.0 5.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KIK51473.1 - 4.6e-16 59.6 0.0 1.1e-14 55.1 0.0 2.8 2 1 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 KIK51473.1 - 5.4e-08 33.3 0.0 1.9e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KIK51473.1 - 1.6e-07 32.1 1.1 3.5e-05 24.5 0.2 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KIK51473.1 - 0.0058 16.0 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF3460 PF11943.8 KIK51474.1 - 0.15 12.4 0.3 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) APG6_N PF17675.1 KIK51475.1 - 0.0028 18.2 20.5 0.0093 16.5 15.1 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region Plasmid_RAQPRD PF09686.10 KIK51475.1 - 0.072 13.3 0.7 0.072 13.3 0.7 2.2 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-C4H2 PF10146.9 KIK51475.1 - 0.13 12.6 19.8 0.024 15.0 15.5 1.7 1 1 1 2 2 2 0 Zinc finger-containing protein GAS PF13851.6 KIK51475.1 - 0.29 10.4 22.6 2.3 7.5 16.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 KIK51475.1 - 0.71 8.4 11.6 1.1 7.8 11.5 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A CdvA PF18822.1 KIK51475.1 - 1.3 8.9 16.0 1 9.2 4.2 2.7 2 1 1 3 3 3 0 CdvA-like coiled-coil domain RasGAP_C PF03836.15 KIK51475.1 - 1.4 9.1 15.2 1.2 9.3 11.4 2.2 1 1 1 2 2 2 0 RasGAP C-terminus NYD-SP28 PF14772.6 KIK51475.1 - 1.8 8.7 21.6 0.61 10.2 7.4 3.1 1 1 1 2 2 2 0 Sperm tail TPR_MLP1_2 PF07926.12 KIK51475.1 - 1.9 8.6 24.5 1.9 8.6 19.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2951 PF11166.8 KIK51475.1 - 2.2 8.5 6.4 6.9 7.0 6.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Spc7 PF08317.11 KIK51475.1 - 2.9 6.7 21.7 4.2 6.2 21.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ISG65-75 PF11727.8 KIK51475.1 - 3.5 6.8 15.0 0.28 10.4 9.8 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein Syntaxin-6_N PF09177.11 KIK51475.1 - 3.6 8.2 13.8 1.5 9.4 8.6 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal KLRAQ PF10205.9 KIK51475.1 - 3.7 7.9 20.3 3.6 7.9 6.9 2.6 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein CC2-LZ PF16516.5 KIK51475.1 - 4 7.9 19.2 22 5.5 13.8 3.2 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 KIK51475.1 - 4.7 7.3 7.8 1.6 8.8 2.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KIK51475.1 - 5.2 4.9 10.0 10 3.9 9.8 1.3 1 1 0 1 1 1 0 Prominin UPF0242 PF06785.11 KIK51475.1 - 8.7 6.4 25.0 1.2 9.2 18.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DMPK_coil PF08826.10 KIK51475.1 - 9.7 6.4 21.4 0.4 10.8 3.4 4.0 2 1 2 4 4 4 0 DMPK coiled coil domain like Glyco_transf_56 PF07429.11 KIK51476.1 - 0.049 12.8 0.2 0.064 12.4 0.2 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 BTB PF00651.31 KIK51479.1 - 0.051 13.8 0.6 0.14 12.4 0.5 1.8 1 1 0 1 1 1 0 BTB/POZ domain CoA_transf_3 PF02515.17 KIK51480.1 - 4.1e-38 131.4 0.0 2.3e-36 125.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III DUF1233 PF06806.12 KIK51485.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative excisionase (DUF1233) zf-C2H2 PF00096.26 KIK51486.1 - 6.6e-07 29.4 10.0 0.016 15.6 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK51486.1 - 5e-06 26.9 9.8 0.041 14.7 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK51486.1 - 0.00014 22.1 11.8 0.026 15.0 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIK51486.1 - 0.013 15.5 1.1 0.037 14.0 1.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 KIK51486.1 - 0.017 15.4 7.6 1.3 9.4 0.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.7 KIK51486.1 - 0.095 12.9 0.5 0.29 11.3 0.3 2.0 2 0 0 2 2 2 0 Zinc-binding CBFD_NFYB_HMF PF00808.23 KIK51487.1 - 1.1e-27 96.1 0.5 1.6e-27 95.6 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK51487.1 - 6.9e-05 23.2 0.0 9.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK51487.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KIK51487.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PAN_3 PF08277.12 KIK51487.1 - 0.072 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain p6 PF17548.2 KIK51489.1 - 0.067 13.2 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 Histone-like Protein p6 DUF2817 PF10994.8 KIK51489.1 - 0.13 11.6 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) TK PF00265.18 KIK51490.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase CALCOCO1 PF07888.11 KIK51491.1 - 2.9e-05 23.1 25.7 5.6e-05 22.2 25.7 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 KIK51491.1 - 0.00026 21.0 22.1 0.00026 21.0 22.1 2.8 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KIK51491.1 - 0.00061 19.5 16.2 0.00061 19.5 16.2 2.3 1 1 1 2 2 2 1 Intermediate filament protein IFT57 PF10498.9 KIK51491.1 - 0.0035 16.4 12.1 0.0035 16.4 12.1 2.1 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 KIK51491.1 - 0.0098 16.2 3.0 0.0098 16.2 3.0 3.3 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 YscO PF07321.12 KIK51491.1 - 0.054 13.5 0.7 0.054 13.5 0.7 3.3 3 1 0 3 3 1 0 Type III secretion protein YscO Tup_N PF08581.10 KIK51491.1 - 0.19 12.1 0.3 0.19 12.1 0.3 3.5 2 1 2 4 4 4 0 Tup N-terminal Gp58 PF07902.11 KIK51491.1 - 0.42 8.9 9.8 0.65 8.2 9.6 1.4 1 1 0 1 1 1 0 gp58-like protein FUSC PF04632.12 KIK51491.1 - 0.47 8.9 8.4 0.73 8.3 8.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4988 PF16378.5 KIK51491.1 - 0.63 9.7 6.6 5.7 6.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function HAP1_N PF04849.13 KIK51491.1 - 0.76 8.9 27.5 1.2 8.3 27.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AAA_13 PF13166.6 KIK51491.1 - 0.92 8.1 25.2 0.029 13.1 3.3 2.6 1 1 1 2 2 2 0 AAA domain DUF4201 PF13870.6 KIK51491.1 - 1 9.0 27.0 0.5 10.1 15.8 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 KIK51491.1 - 1.1 9.5 30.3 0.65 10.2 17.3 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KIK51491.1 - 2.3 7.0 34.1 0.61 8.9 22.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KIK51491.1 - 2.6 7.3 32.7 3 7.2 3.4 2.4 1 1 0 2 2 2 0 Tropomyosin HMMR_N PF15905.5 KIK51491.1 - 3 7.2 33.9 2.7 7.4 5.3 2.4 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 KIK51491.1 - 3.2 8.2 31.6 2.3 8.6 11.7 2.7 2 1 1 3 3 3 0 Fez1 DUF1664 PF07889.12 KIK51491.1 - 3.2 7.8 14.2 0.92 9.6 4.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) MCC-bdg_PDZ PF10506.9 KIK51491.1 - 3.4 7.8 20.5 0.4 10.7 8.3 3.7 2 2 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APC_N_CC PF16689.5 KIK51491.1 - 3.4 7.8 16.7 0.18 11.9 3.9 3.0 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF724 PF05266.14 KIK51491.1 - 4.6 7.0 24.1 0.28 11.0 15.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Rab5-bind PF09311.11 KIK51491.1 - 5.6 6.3 31.9 3.8 6.8 3.5 3.2 1 1 2 3 3 3 0 Rabaptin-like protein GAS PF13851.6 KIK51491.1 - 6.9 6.0 34.7 20 4.4 5.1 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 KIK51491.1 - 7.3 4.4 11.6 2.2 6.2 8.5 1.5 1 1 0 1 1 1 0 Prominin DHR10 PF18595.1 KIK51491.1 - 8.3 6.5 37.0 5.3 7.1 3.7 3.8 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain FapA PF03961.13 KIK51491.1 - 8.3 4.9 22.3 1.3 7.5 8.9 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A KxDL PF10241.9 KIK51491.1 - 8.5 6.7 24.8 0.13 12.6 3.4 3.7 2 1 2 4 4 3 0 Uncharacterized conserved protein Leu_zip PF15294.6 KIK51491.1 - 8.7 5.8 26.8 61 3.0 26.7 2.1 1 1 0 1 1 1 0 Leucine zipper Spectrin PF00435.21 KIK51491.1 - 10 6.7 33.3 0.81 10.2 1.6 3.5 2 1 2 4 4 3 0 Spectrin repeat Taxilin PF09728.9 KIK51493.1 - 0.001 18.3 15.9 0.001 18.3 15.9 2.2 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF3450 PF11932.8 KIK51493.1 - 0.0018 17.6 19.1 0.0018 17.6 19.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 KIK51493.1 - 0.01 15.7 25.3 0.01 15.7 25.3 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CALCOCO1 PF07888.11 KIK51493.1 - 0.012 14.5 30.3 0.059 12.2 30.3 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Myosin_tail_1 PF01576.19 KIK51493.1 - 0.088 10.6 27.1 0.11 10.2 27.1 1.0 1 0 0 1 1 1 0 Myosin tail UPF0184 PF03670.13 KIK51493.1 - 0.15 12.5 7.0 0.069 13.5 3.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) FapA PF03961.13 KIK51493.1 - 0.18 10.4 15.6 0.27 9.8 15.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lebercilin PF15619.6 KIK51493.1 - 0.23 11.1 34.8 13 5.4 26.3 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 KIK51493.1 - 0.27 11.3 31.8 1.4 9.0 2.7 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KIK51493.1 - 0.37 10.1 30.1 0.18 11.1 22.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KIK51493.1 - 0.42 10.7 29.5 0.16 12.0 21.6 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Pox_A_type_inc PF04508.12 KIK51493.1 - 0.44 10.5 0.1 0.44 10.5 0.1 3.2 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat DUF150_C PF17384.2 KIK51493.1 - 0.47 10.6 4.0 1.6 8.9 1.7 2.4 2 0 0 2 2 2 0 RimP C-terminal SH3 domain DUF4164 PF13747.6 KIK51493.1 - 0.56 10.5 18.3 0.11 12.8 7.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) YabA PF06156.13 KIK51493.1 - 0.62 10.7 27.3 2.3 8.9 16.9 3.5 3 1 1 4 4 3 0 Initiation control protein YabA LCD1 PF09798.9 KIK51493.1 - 0.77 8.2 12.6 1.4 7.3 12.6 1.5 1 0 0 1 1 1 0 DNA damage checkpoint protein Leu_zip PF15294.6 KIK51493.1 - 1.1 8.7 24.1 0.25 10.9 19.6 1.9 1 1 1 2 2 2 0 Leucine zipper DUF2353 PF09789.9 KIK51493.1 - 1.1 8.5 25.2 0.46 9.8 18.7 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Swi5 PF07061.11 KIK51493.1 - 1.8 8.7 21.6 11 6.2 0.2 3.7 3 1 0 3 3 3 0 Swi5 TMPIT PF07851.13 KIK51493.1 - 2.1 7.5 20.8 0.064 12.5 11.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 KIK51493.1 - 2.3 8.3 31.4 0.089 12.9 14.9 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KIK51493.1 - 2.4 6.7 18.3 3.3 6.2 18.3 1.1 1 0 0 1 1 1 0 AAA domain KxDL PF10241.9 KIK51493.1 - 2.5 8.4 16.5 0.11 12.8 4.3 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein MscS_porin PF12795.7 KIK51493.1 - 2.7 7.5 35.3 3.6 7.1 6.0 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Tli4_N PF18443.1 KIK51493.1 - 3 8.2 6.9 8 6.8 6.8 1.8 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain KELK PF15796.5 KIK51493.1 - 3.3 8.2 26.1 0.2 12.1 2.4 3.2 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4201 PF13870.6 KIK51493.1 - 3.4 7.4 29.2 1.6 8.4 23.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 KIK51493.1 - 3.8 8.0 33.3 0.37 11.3 24.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 KIK51493.1 - 4 7.5 16.1 0.3 11.1 1.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 KIK51493.1 - 4.7 7.0 33.9 0.85 9.4 27.4 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family bZIP_2 PF07716.15 KIK51493.1 - 5.8 7.1 30.0 8 6.6 10.3 4.7 2 2 3 5 5 5 0 Basic region leucine zipper FUSC PF04632.12 KIK51493.1 - 6 5.3 6.9 5.4 5.4 5.6 1.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family HAP1_N PF04849.13 KIK51493.1 - 6.3 5.9 26.4 13 4.8 26.4 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region ATG16 PF08614.11 KIK51493.1 - 6.9 6.8 34.2 0.2 11.9 22.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 KIK51493.1 - 9.2 6.2 28.9 1.8e+02 2.0 28.6 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CLZ PF16526.5 KIK51493.1 - 9.8 6.6 26.3 2.5 8.5 8.8 3.7 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Raftlin PF15250.6 KIK51498.1 - 0.31 9.7 2.4 0.37 9.5 2.4 1.1 1 0 0 1 1 1 0 Raftlin DUF2722 PF10846.8 KIK51498.1 - 1.3 7.9 12.1 1.3 7.9 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) IFT57 PF10498.9 KIK51498.1 - 1.6 7.6 9.5 1.7 7.5 9.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NPR3 PF03666.13 KIK51498.1 - 5.8 5.6 4.8 6.4 5.4 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 KIK51498.1 - 7.8 4.6 27.2 8.9 4.4 27.2 1.1 1 0 0 1 1 1 0 Nop14-like family PTP2 PF17022.5 KIK51500.1 - 0.045 13.4 0.3 0.047 13.3 0.3 1.1 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia CoA_transf_3 PF02515.17 KIK51501.1 - 2.2e-38 132.4 0.0 7.7e-37 127.3 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Imm3 PF14425.6 KIK51503.1 - 0.052 13.6 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Immunity protein Imm3 BTB PF00651.31 KIK51504.1 - 0.012 15.8 0.7 0.066 13.5 0.7 2.1 1 1 0 1 1 1 0 BTB/POZ domain Herpes_HEPA PF03324.14 KIK51507.1 - 0.12 12.9 0.5 0.34 11.4 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein Cytochrom_B562 PF07361.11 KIK51508.1 - 0.069 13.8 0.2 0.12 13.0 0.2 1.4 1 0 0 1 1 1 0 Cytochrome b562 DUF4413 PF14372.6 KIK51508.1 - 0.085 13.2 0.6 0.16 12.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) His_Phos_1 PF00300.22 KIK51508.1 - 0.13 11.9 2.9 0.22 11.2 0.8 2.0 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) YfhD PF14151.6 KIK51509.1 - 1.1 9.5 5.3 0.34 11.1 0.8 2.6 2 0 0 2 2 2 0 YfhD-like protein Csm1_N PF18504.1 KIK51509.1 - 1.2 9.6 5.7 3.9 7.9 1.7 3.0 1 1 1 2 2 2 0 Csm1 N-terminal domain CxC4 PF18717.1 KIK51512.1 - 2.8e-46 156.6 0.2 5.1e-46 155.7 0.2 1.5 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases Zn_Tnp_IS1595 PF12760.7 KIK51512.1 - 0.27 11.2 3.2 22 5.1 0.0 3.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Tyrosinase PF00264.20 KIK51515.1 - 2.2e-43 149.1 2.4 5.4e-43 147.9 2.4 1.7 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 KIK51516.1 - 6.2e-18 65.9 0.3 6.2e-18 65.9 0.3 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase adh_short PF00106.25 KIK51517.1 - 8.3e-12 45.0 0.1 2.8e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK51517.1 - 2.3e-09 37.2 0.0 4e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK51517.1 - 2.3e-07 30.9 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK51517.1 - 0.0058 16.9 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 KIK51517.1 - 0.17 12.3 0.1 0.38 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) F-box-like PF12937.7 KIK51518.1 - 3.1e-05 23.8 0.1 9.7e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK51518.1 - 0.0035 17.2 0.3 0.28 11.1 0.0 2.3 2 0 0 2 2 2 2 F-box domain DUF648 PF04890.13 KIK51521.1 - 0.014 15.2 0.4 0.02 14.7 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF327 PF03885.13 KIK51521.1 - 0.02 14.8 0.7 0.035 14.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) TSNAXIP1_N PF15739.5 KIK51521.1 - 0.032 14.6 4.3 0.065 13.6 4.2 1.5 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TED_complement PF07678.14 KIK51521.1 - 0.041 12.9 0.1 0.059 12.4 0.1 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF745 PF05335.13 KIK51521.1 - 0.051 13.3 2.1 1.2 8.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Tox-ODYAM1 PF15642.6 KIK51521.1 - 0.093 11.7 0.8 0.13 11.2 0.8 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus UPF0242 PF06785.11 KIK51521.1 - 0.25 11.4 5.0 0.38 10.8 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 KIK51521.1 - 0.32 10.9 3.7 5.2 7.0 0.3 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KIK51522.1 - 0.086 11.7 6.8 0.13 11.1 6.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MCU PF04678.13 KIK51522.1 - 1.6 8.8 4.4 3 7.9 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Csm1_N PF18504.1 KIK51522.1 - 3.5 8.0 9.4 3.6 8.0 6.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain PEP-utilisers_N PF05524.13 KIK51522.1 - 7.3 6.8 7.5 24 5.1 7.5 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal OTT_1508_deam PF14441.6 KIK51523.1 - 5.9e-07 29.4 0.1 1.6e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase LRR_8 PF13855.6 KIK51524.1 - 1.2e-15 57.0 9.0 2.6e-10 39.9 1.8 3.5 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KIK51524.1 - 7.2e-11 42.2 13.6 9.4e-06 25.9 1.2 4.7 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIK51524.1 - 0.0087 15.6 0.2 0.026 14.0 0.1 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KIK51524.1 - 0.051 13.6 6.9 0.12 12.5 0.4 4.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KIK51524.1 - 0.53 11.0 14.5 4.5 8.2 2.0 5.2 4 2 0 4 4 4 0 Leucine Rich Repeat DNA_topoisoIV PF00521.20 KIK51525.1 - 5.5e-102 341.8 0.3 1.4e-101 340.5 0.3 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIK51525.1 - 5.6e-29 101.0 2.3 6.8e-21 74.9 0.1 3.3 2 1 1 3 3 3 2 C-terminal associated domain of TOPRIM HATPase_c PF02518.26 KIK51525.1 - 6.7e-11 42.7 0.1 1.6e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIK51525.1 - 3.3e-08 33.7 0.0 3.3e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Toprim domain BUD22 PF09073.10 KIK51526.1 - 3.1 7.1 40.8 3.8 6.7 40.8 1.2 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 KIK51526.1 - 6.5 6.1 15.4 8.9 5.6 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase_fungal PF17667.1 KIK51527.1 - 1.2e-15 57.2 0.0 3.1e-12 46.0 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK51527.1 - 0.00037 20.0 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK51527.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK51527.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIK51528.1 - 1.3e-34 119.7 0.0 1.1e-31 110.1 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK51528.1 - 1.6e-07 31.0 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK51528.1 - 0.0036 17.3 0.1 0.0052 16.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK51528.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KIK51528.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RicinB_lectin_2 PF14200.6 KIK51529.1 - 3.5e-12 46.9 0.7 3.6e-06 27.6 0.3 3.3 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PHINT_rpt PF14882.6 KIK51529.1 - 0.047 14.0 0.1 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 Phage-integrase repeat unit LMWPc PF01451.21 KIK51529.1 - 0.097 13.0 0.0 1.1 9.6 0.0 2.1 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Pkinase_fungal PF17667.1 KIK51531.1 - 9.5e-37 126.7 0.0 1.8e-32 112.7 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK51531.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK51531.1 - 0.0046 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK51531.1 - 0.0053 16.4 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KIK51531.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK51533.1 - 6e-49 166.9 0.1 7.4e-32 110.6 1.3 2.0 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK51533.1 - 7.1e-07 29.4 1.2 3.2e-06 27.2 0.6 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK51533.1 - 0.00064 19.2 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KIK51533.1 - 0.0032 16.5 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIK51533.1 - 0.024 14.3 0.3 0.038 13.6 0.3 1.3 1 0 0 1 1 1 0 RIO1 family RE_Bpu10I PF09549.10 KIK51533.1 - 0.09 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Bpu10I restriction endonuclease Pkinase_Tyr PF07714.17 KIK51533.1 - 0.12 11.7 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 KIK51534.1 - 1.5e-09 38.3 0.3 0.00062 20.3 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK51534.1 - 5.4e-08 32.5 0.5 0.017 15.6 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK51534.1 - 1.3e-06 28.6 0.5 0.093 13.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK51534.1 - 5.7e-06 26.8 0.2 0.00079 19.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK51534.1 - 4.6e-05 23.7 4.0 0.014 15.8 0.3 3.5 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KIK51534.1 - 0.0021 17.9 0.1 0.046 13.6 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Retrotrans_gag PF03732.17 KIK51535.1 - 4.1e-09 36.6 2.1 5.2e-09 36.3 0.6 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein Snapin_Pallidin PF14712.6 KIK51535.1 - 0.031 14.7 0.6 12 6.4 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF1490 PF07371.12 KIK51535.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) Lipase PF00151.19 KIK51535.1 - 0.074 12.3 2.0 0.13 11.6 2.0 1.3 1 0 0 1 1 1 0 Lipase Cyclin_C PF02984.19 KIK51535.1 - 0.089 12.9 0.1 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Cyclin, C-terminal domain QH-AmDH_gamma PF08992.11 KIK51535.1 - 0.096 12.7 0.1 0.32 11.0 0.1 1.9 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Ank_2 PF12796.7 KIK51536.1 - 2.2e-09 37.8 0.0 3.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK51536.1 - 7.8e-06 25.9 0.0 0.034 14.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KIK51536.1 - 0.00062 20.3 0.0 3 8.5 0.0 2.5 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK51536.1 - 0.068 13.6 0.0 3.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat D123 PF07065.14 KIK51536.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 D123 Ank_2 PF12796.7 KIK51538.1 - 1.2e-09 38.6 0.6 0.00063 20.3 0.5 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK51538.1 - 2e-08 33.8 1.9 0.014 15.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIK51538.1 - 7.5e-07 29.3 0.9 0.071 13.5 0.2 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK51538.1 - 3.9e-06 27.3 0.1 0.00078 20.0 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK51538.1 - 2.7e-05 24.4 3.6 0.031 14.7 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KIK51538.1 - 0.047 13.5 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 KilA-N domain DUF4293 PF14126.6 KIK51540.1 - 0.049 13.9 0.8 0.073 13.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3313 PF11769.8 KIK51541.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) WD40 PF00400.32 KIK51542.1 - 6.5e-78 254.7 30.0 3.7e-10 40.2 0.7 9.6 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51542.1 - 3.1e-31 107.5 0.3 0.015 15.6 0.0 8.1 2 1 6 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK51542.1 - 8.1e-19 67.1 14.6 0.22 11.5 0.0 9.3 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK51542.1 - 1.2e-17 63.9 0.3 0.12 11.3 0.0 8.0 3 1 5 8 8 8 7 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK51542.1 - 1.4e-08 34.8 0.0 0.029 14.3 0.0 4.0 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK51542.1 - 1e-06 28.3 0.0 0.5 9.6 0.0 4.5 4 2 0 5 5 5 2 WD40-like domain Frtz PF11768.8 KIK51542.1 - 1.3e-05 23.8 0.0 14 3.9 0.0 5.8 2 1 3 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK51542.1 - 8.1e-05 22.2 11.4 27 4.6 0.1 8.3 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KIK51542.1 - 8.2e-05 21.3 0.1 0.11 11.0 0.0 3.1 2 1 2 4 4 4 2 Cytochrome D1 heme domain DHFR_2 PF06442.11 KIK51542.1 - 0.0014 18.4 1.6 0.52 10.2 0.0 4.7 3 1 3 6 6 6 1 R67 dihydrofolate reductase Nbas_N PF15492.6 KIK51542.1 - 0.0043 16.4 1.9 17 4.6 0.0 4.8 3 1 3 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK51542.1 - 0.0054 15.4 2.9 3.8 6.0 0.0 4.6 4 2 3 7 7 7 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK51542.1 - 0.04 12.7 0.2 3.3 6.3 0.0 3.2 2 1 0 3 3 3 0 Nup133 N terminal like NACHT PF05729.12 KIK51543.1 - 1.6e-07 31.4 0.1 2.1e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK51543.1 - 2.7e-05 24.6 0.0 4.2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK51543.1 - 0.0012 18.0 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 KIK51543.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KIK51543.1 - 0.0073 16.7 0.3 0.016 15.7 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KIK51543.1 - 0.0097 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase DUF2075 PF09848.9 KIK51543.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4914 PF16260.5 KIK51543.1 - 0.029 12.5 0.0 0.035 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) IstB_IS21 PF01695.17 KIK51543.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 KIK51543.1 - 0.044 13.0 1.0 0.35 10.1 0.3 2.0 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.16 KIK51543.1 - 0.053 13.0 0.1 0.088 12.2 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KIK51543.1 - 0.054 13.4 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KIK51543.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 KIK51543.1 - 0.12 12.7 0.1 0.26 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK51543.1 - 0.19 10.8 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AhpC-TSA PF00578.21 KIK51545.1 - 9.5e-11 41.7 0.0 2.4e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 AhpC/TSA family RPW8 PF05659.11 KIK51545.1 - 0.005 16.5 0.7 0.005 16.5 0.7 2.9 3 0 0 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 FeoB_Cyto PF17910.1 KIK51545.1 - 0.016 15.8 0.4 0.051 14.1 0.4 1.9 1 0 0 1 1 1 0 FeoB cytosolic helical domain Med9 PF07544.13 KIK51545.1 - 0.14 12.3 0.8 7.9 6.6 0.1 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2730 PF10805.8 KIK51545.1 - 0.21 11.7 1.2 0.55 10.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4795 PF16043.5 KIK51545.1 - 2 8.0 8.8 1 9.0 6.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DASH_Dam1 PF08653.10 KIK51545.1 - 2.2 8.1 3.8 9.1 6.2 0.7 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 Arm PF00514.23 KIK51546.1 - 6.3e-05 22.9 6.0 4 7.6 0.0 6.5 5 2 1 6 6 6 2 Armadillo/beta-catenin-like repeat Exo70 PF03081.15 KIK51546.1 - 0.33 9.9 0.4 0.53 9.3 0.4 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit HEAT_EZ PF13513.6 KIK51546.1 - 0.94 10.1 17.2 15 6.3 0.1 7.1 9 0 0 9 9 9 0 HEAT-like repeat Dimer_Tnp_hAT PF05699.14 KIK51547.1 - 1.5e-10 40.7 0.0 2.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_hydro_42 PF02449.15 KIK51548.1 - 0.24 10.7 0.0 0.36 10.1 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase DUF1345 PF07077.11 KIK51548.1 - 0.61 9.8 8.9 0.52 10.0 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Linker_histone PF00538.19 KIK51549.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family Peptidase_M20 PF01546.28 KIK51550.1 - 2.1e-29 102.7 0.0 2.9e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK51550.1 - 2.4e-11 43.5 0.0 4.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RdRP PF05183.12 KIK51552.1 - 1.2e-117 394.0 0.0 1.5e-117 393.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Gate PF07670.14 KIK51554.1 - 2.5 8.4 5.6 1.3 9.4 1.5 2.1 1 1 1 2 2 2 0 Nucleoside recognition Tmemb_55A PF09788.9 KIK51556.1 - 0.045 12.8 1.0 0.085 11.9 1.0 1.5 1 1 0 1 1 1 0 Transmembrane protein 55A PNP_UDP_1 PF01048.20 KIK51557.1 - 7.5e-38 130.1 0.2 9.5e-38 129.8 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily TagA PF12561.8 KIK51557.1 - 0.038 14.4 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain ABC_tran PF00005.27 KIK51558.1 - 1.9e-43 148.3 0.2 3.4e-28 98.9 0.1 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK51558.1 - 2e-43 149.1 25.3 2.3e-23 83.2 3.8 3.0 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK51558.1 - 3.8e-11 42.9 7.2 0.0017 17.8 4.3 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK51558.1 - 4.5e-06 27.2 0.4 0.045 14.1 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIK51558.1 - 6.4e-06 25.8 0.2 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK51558.1 - 3.9e-05 23.6 5.7 0.23 11.3 0.1 4.3 4 1 1 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KIK51558.1 - 4.8e-05 23.6 3.8 0.0065 16.6 0.0 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KIK51558.1 - 4.9e-05 23.9 3.8 0.0073 16.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KIK51558.1 - 0.00055 19.6 0.0 0.12 11.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KIK51558.1 - 0.00056 20.2 0.1 1.8 8.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KIK51558.1 - 0.0007 19.0 0.1 0.25 10.7 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 KIK51558.1 - 0.00088 18.8 0.1 0.36 10.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 KIK51558.1 - 0.001 18.2 0.0 0.96 8.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Reticulon PF02453.17 KIK51558.1 - 0.0012 18.9 6.0 0.081 12.9 0.0 3.9 2 1 0 2 2 2 1 Reticulon MMR_HSR1 PF01926.23 KIK51558.1 - 0.0012 18.9 0.2 0.22 11.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Pox_A32 PF04665.12 KIK51558.1 - 0.0033 16.9 1.0 1.4 8.3 0.1 2.4 2 0 0 2 2 2 2 Poxvirus A32 protein AAA_15 PF13175.6 KIK51558.1 - 0.0053 16.5 1.0 0.59 9.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 KIK51558.1 - 0.012 14.9 0.1 0.16 11.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KIK51558.1 - 0.017 14.0 0.2 2.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KIK51558.1 - 0.017 14.9 0.1 6.7 6.4 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KIK51558.1 - 0.019 15.0 0.6 11 6.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KIK51558.1 - 0.02 15.0 3.8 3 7.9 0.1 3.2 3 0 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 KIK51558.1 - 0.02 14.8 0.7 3.7 7.4 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KIK51558.1 - 0.021 14.6 0.2 3.7 7.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK51558.1 - 0.025 13.7 0.0 8 5.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 KIK51558.1 - 0.03 14.3 0.1 4.5 7.2 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KIK51558.1 - 0.039 13.9 0.1 12 5.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KIK51558.1 - 0.084 12.8 1.6 7.2 6.5 0.0 2.9 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KIK51558.1 - 0.12 12.9 0.0 55 4.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KIK51558.1 - 0.12 12.8 0.3 32 4.9 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 KIK51558.1 - 0.13 11.0 0.2 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Roc PF08477.13 KIK51558.1 - 0.14 12.4 0.1 35 4.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KIK51558.1 - 0.23 11.0 1.3 4.9 6.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Phage_Gp23 PF10669.9 KIK51558.1 - 0.26 11.6 3.6 1.3 9.4 2.2 2.5 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2075 PF09848.9 KIK51558.1 - 5.4 6.2 12.6 3.8 6.7 1.5 3.1 3 1 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) DUF2561 PF10812.8 KIK51558.1 - 7.3 6.6 7.2 5.5 7.0 0.4 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2561) PGPGW PF09656.10 KIK51558.1 - 8.4 6.0 11.6 0.56 9.8 4.8 2.5 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) RVP_2 PF08284.11 KIK51559.1 - 0.045 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 KIK51563.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 KIK51563.1 - 4.5 7.1 6.6 9.2 6.1 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C14 PF00656.22 KIK51565.1 - 1e-21 78.1 0.0 1.4e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.32 KIK51566.1 - 6.8e-24 83.7 7.4 2.8e-09 37.5 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51566.1 - 5.5e-07 29.8 0.0 0.027 14.8 0.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK51566.1 - 4.2e-05 23.0 0.0 0.5 9.6 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 KIK51566.1 - 0.0002 21.3 0.1 0.0051 16.7 0.0 2.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A nos_propeller PF18764.1 KIK51566.1 - 0.0039 17.1 1.4 1 9.3 0.2 2.4 1 1 1 2 2 2 2 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KIK51566.1 - 0.02 13.5 0.4 0.37 9.4 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK51566.1 - 0.026 15.0 0.6 0.35 11.4 0.0 2.6 1 1 1 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 KIK51566.1 - 0.03 13.3 0.1 1 8.2 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Shisa PF13908.6 KIK51567.1 - 0.0044 17.3 2.4 0.046 14.0 0.1 2.1 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.6 KIK51567.1 - 0.0054 16.6 0.1 0.0098 15.8 0.0 1.4 2 0 0 2 2 2 1 Transmembrane protein 51 Herpes_gE PF02480.16 KIK51567.1 - 0.009 14.8 0.4 0.027 13.2 0.4 1.7 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.20 KIK51567.1 - 0.11 12.4 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KIK51567.1 - 0.13 13.1 0.0 0.2 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Asp PF00026.23 KIK51568.1 - 2.9e-22 79.5 3.7 1.1e-20 74.3 3.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease E_Pc_C PF06752.12 KIK51568.1 - 0.027 14.6 1.2 0.045 13.9 1.2 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus GLEYA PF10528.9 KIK51568.1 - 0.055 13.9 0.4 19 5.8 0.0 2.7 2 0 0 2 2 2 0 GLEYA domain Dimer_Tnp_hAT PF05699.14 KIK51569.1 - 0.036 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2782 PF11191.8 KIK51570.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) Nop14 PF04147.12 KIK51571.1 - 5.2 5.1 6.3 5.7 5.0 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 KIK51572.1 - 4.1e-140 451.5 41.1 6.1e-11 42.7 0.1 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51572.1 - 8.5e-38 128.6 7.4 0.018 15.3 0.0 12.6 2 2 11 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51572.1 - 2.7e-23 82.9 8.1 9.6e-05 22.3 0.2 7.5 3 2 5 8 8 8 7 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK51572.1 - 5.5e-16 58.3 22.3 0.18 10.4 0.0 9.9 3 2 4 10 10 10 6 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK51572.1 - 9.1e-15 54.4 8.6 0.85 8.5 0.0 10.5 2 2 10 12 12 12 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK51572.1 - 9.9e-12 44.8 1.1 1.8 7.8 0.0 8.9 6 3 3 9 9 9 2 WD40-like domain PD40 PF07676.12 KIK51572.1 - 1.9e-10 40.4 6.5 6.9 6.7 0.0 11.3 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK51572.1 - 5.3e-08 32.7 22.5 8.1 6.4 0.0 12.1 13 0 0 13 13 13 1 Nitrous oxide reductase propeller repeat Str_synth PF03088.16 KIK51572.1 - 4.9e-07 29.8 1.2 38 4.5 0.0 7.7 8 1 0 8 8 7 0 Strictosidine synthase COPI_C PF06957.11 KIK51572.1 - 1.7e-05 23.8 0.0 11 4.6 0.0 5.2 2 1 3 5 5 5 0 Coatomer (COPI) alpha subunit C-terminus SdiA-regulated PF06977.11 KIK51572.1 - 0.00023 20.5 0.0 1.9 7.7 0.0 4.6 3 2 3 6 6 6 1 SdiA-regulated MMS1_N PF10433.9 KIK51572.1 - 0.00073 18.3 0.0 2 6.9 0.0 3.3 2 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term NHL PF01436.21 KIK51572.1 - 0.001 19.0 14.1 16 5.8 0.0 9.3 12 0 0 12 12 11 0 NHL repeat potato_inhibit PF00280.18 KIK51572.1 - 0.0016 19.1 4.7 55 4.5 0.0 7.4 7 1 2 9 9 7 0 Potato inhibitor I family PLL PF18587.1 KIK51572.1 - 0.011 15.9 0.0 3.8 7.6 0.0 4.0 2 1 2 4 4 4 0 PTX/LNS-Like (PLL) domain Kelch_2 PF07646.15 KIK51572.1 - 0.012 15.5 4.0 1.1 9.3 0.2 5.4 6 0 0 6 6 5 0 Kelch motif SoxZ PF08770.11 KIK51572.1 - 0.038 13.8 0.5 36 4.2 0.0 5.1 7 1 0 7 7 6 0 Sulphur oxidation protein SoxZ AsnC_trans_reg PF01037.21 KIK51572.1 - 0.09 12.7 0.0 43 4.2 0.0 4.7 5 0 0 5 5 5 0 Lrp/AsnC ligand binding domain Cuticle_4 PF15955.5 KIK51572.1 - 0.097 13.4 0.7 1.2e+02 3.5 0.0 5.6 7 0 0 7 7 6 0 Cuticle protein NACHT PF05729.12 KIK51572.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain LMBR1 PF04791.16 KIK51573.1 - 0.0082 15.1 0.0 0.0095 14.9 0.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein HrpB7 PF09486.10 KIK51573.1 - 0.017 15.5 0.3 0.021 15.2 0.3 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4203 PF13886.6 KIK51573.1 - 0.03 14.0 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Med4 PF10018.9 KIK51573.1 - 0.037 13.7 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HisK_N PF09385.10 KIK51573.1 - 0.046 13.7 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase N terminal SLATT_1 PF18181.1 KIK51573.1 - 0.12 12.3 0.2 0.16 11.9 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Remorin_C PF03763.13 KIK51573.1 - 0.14 12.0 0.5 0.2 11.6 0.5 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region Lectin_N PF03954.14 KIK51573.1 - 0.19 11.5 1.1 0.29 10.9 1.1 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Pox_A_type_inc PF04508.12 KIK51573.1 - 0.27 11.1 1.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat WD40 PF00400.32 KIK51576.1 - 1.1e-151 488.1 51.3 1.1e-10 41.9 0.0 17.8 17 0 0 17 17 17 16 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51576.1 - 2.4e-37 127.1 14.1 0.0027 18.0 0.1 14.1 2 2 13 15 15 15 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51576.1 - 1.6e-26 93.4 5.4 0.00016 21.6 0.2 7.4 3 2 3 7 7 7 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK51576.1 - 3.8e-16 58.8 27.1 0.38 9.3 0.1 11.4 6 3 4 12 12 12 8 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK51576.1 - 8.4e-16 58.2 2.0 0.74 9.1 0.0 10.3 8 2 3 11 11 11 4 WD40-like domain NACHT PF05729.12 KIK51576.1 - 3.2e-08 33.7 0.0 6.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain nos_propeller PF18764.1 KIK51576.1 - 1.3e-07 31.4 25.6 7.1 6.6 0.0 13.0 14 1 1 15 15 15 1 Nitrous oxide reductase propeller repeat MMS1_N PF10433.9 KIK51576.1 - 3e-07 29.4 0.0 0.21 10.2 0.0 5.5 4 2 1 6 6 6 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 KIK51576.1 - 3.5e-07 29.5 2.4 18 4.1 0.0 9.0 3 3 7 11 11 11 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51576.1 - 2e-05 24.4 4.4 36 4.5 0.0 9.8 13 0 0 13 13 12 0 WD40-like Beta Propeller Repeat NHL PF01436.21 KIK51576.1 - 5.5e-05 23.0 12.5 25 5.2 0.0 9.9 11 0 0 11 11 11 0 NHL repeat Peptidase_S9_N PF02897.15 KIK51576.1 - 0.00035 19.5 9.3 0.62 8.8 0.0 6.9 3 2 4 8 8 8 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Str_synth PF03088.16 KIK51576.1 - 0.00046 20.3 0.2 35 4.6 0.0 6.7 6 2 3 9 9 9 0 Strictosidine synthase AAA_16 PF13191.6 KIK51576.1 - 0.0011 19.4 0.0 0.0033 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain SdiA-regulated PF06977.11 KIK51576.1 - 0.0019 17.4 0.0 2.4 7.3 0.0 4.8 2 2 5 7 7 7 1 SdiA-regulated APS_kinase PF01583.20 KIK51576.1 - 0.0033 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK51576.1 - 0.012 16.1 0.0 0.034 14.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK51576.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KIK51576.1 - 0.14 12.7 0.3 0.55 10.8 0.0 2.2 2 1 0 2 2 1 0 AAA domain Cuticle_4 PF15955.5 KIK51576.1 - 0.25 12.0 8.9 1.5e+02 3.1 0.1 7.1 9 0 0 9 9 8 0 Cuticle protein TENA_THI-4 PF03070.16 KIK51577.1 - 4e-09 36.6 0.1 6.7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Cellulase PF00150.18 KIK51578.1 - 5.3e-07 29.3 0.0 9.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HHV-5_US34A PF17087.5 KIK51578.1 - 1.1 9.5 4.6 1.9 8.7 4.6 1.3 1 0 0 1 1 1 0 Herpesvirus US34A protein family WD40 PF00400.32 KIK51579.1 - 6.8e-125 403.3 47.0 2.2e-12 47.3 0.3 12.7 13 0 0 13 13 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51579.1 - 4.9e-36 122.9 9.3 0.0024 18.1 0.0 11.5 1 1 10 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51579.1 - 1.1e-18 67.9 3.0 0.0018 18.2 0.0 6.1 1 1 6 7 7 7 7 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK51579.1 - 4.8e-11 42.5 0.1 0.3 10.4 0.0 8.4 4 3 6 10 10 10 2 WD40-like domain Ge1_WD40 PF16529.5 KIK51579.1 - 3e-10 39.6 8.9 2.6 6.9 0.0 9.7 2 1 8 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK51579.1 - 7.9e-10 38.9 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK51579.1 - 2.8e-09 36.7 0.1 24 5.0 0.0 9.0 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK51579.1 - 3.3e-09 36.0 26.1 0.47 9.0 0.1 10.0 1 1 10 12 12 12 4 Nucleoporin Nup120/160 potato_inhibit PF00280.18 KIK51579.1 - 5.3e-08 33.4 0.8 39 5.0 0.0 8.9 7 2 4 11 11 9 0 Potato inhibitor I family AAA_16 PF13191.6 KIK51579.1 - 9.5e-06 26.1 0.0 3.1e-05 24.4 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain nos_propeller PF18764.1 KIK51579.1 - 0.00015 21.6 24.6 11 6.1 0.1 10.1 10 2 1 11 11 10 0 Nitrous oxide reductase propeller repeat COPI_C PF06957.11 KIK51579.1 - 0.00026 19.9 0.0 1.2 7.8 0.0 3.4 3 1 0 3 3 3 2 Coatomer (COPI) alpha subunit C-terminus DsbC_N PF10411.9 KIK51579.1 - 0.00032 20.1 0.3 94 2.6 0.0 6.9 7 0 0 7 7 7 0 Disulfide bond isomerase protein N-terminus Coatomer_WDAD PF04053.14 KIK51579.1 - 0.0012 18.0 6.0 0.0072 15.4 0.5 3.7 1 1 3 4 4 4 1 Coatomer WD associated region AAA PF00004.29 KIK51579.1 - 0.0012 19.2 0.1 0.0069 16.8 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Cuticle_4 PF15955.5 KIK51579.1 - 0.0014 19.2 2.2 1.9e+02 2.9 0.0 7.4 9 1 0 9 9 9 0 Cuticle protein APS_kinase PF01583.20 KIK51579.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase NHL PF01436.21 KIK51579.1 - 0.019 15.0 9.4 37 4.6 0.0 7.5 9 0 0 9 9 8 0 NHL repeat SoxZ PF08770.11 KIK51579.1 - 0.019 14.7 0.2 18 5.2 0.0 4.5 5 1 1 6 6 4 0 Sulphur oxidation protein SoxZ SdiA-regulated PF06977.11 KIK51579.1 - 0.027 13.7 0.0 17 4.5 0.0 4.3 2 2 2 5 5 5 0 SdiA-regulated AsnC_trans_reg PF01037.21 KIK51579.1 - 0.035 14.1 0.5 2.1e+02 2.0 0.0 5.6 6 0 0 6 6 5 0 Lrp/AsnC ligand binding domain ATPase_2 PF01637.18 KIK51579.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK51579.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain IKI3 PF04762.12 KIK51579.1 - 1.2 7.1 12.1 0.69 7.8 4.2 3.5 1 1 2 4 4 4 0 IKI3 family SymE_toxin PF08845.10 KIK51579.1 - 9.8 6.3 11.0 15 5.7 0.2 4.2 4 0 0 4 4 4 0 Toxin SymE, type I toxin-antitoxin system ACPS PF01648.20 KIK51581.1 - 0.069 13.3 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DUF2269 PF10027.9 KIK51581.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) T-box_assoc PF16176.5 KIK51582.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 T-box transcription factor-associated WD40 PF00400.32 KIK51583.1 - 7.2e-158 507.7 59.1 6.3e-11 42.7 0.1 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51583.1 - 2e-35 121.0 20.4 0.083 13.2 0.0 14.3 1 1 13 14 14 14 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK51583.1 - 1.2e-22 80.7 8.9 1.3e-05 25.2 0.1 6.1 1 1 7 8 8 8 8 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK51583.1 - 9.6e-16 57.5 28.2 0.52 8.9 0.0 12.5 7 4 5 13 13 13 9 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK51583.1 - 1.1e-13 51.3 0.1 12 5.1 0.0 11.4 11 1 1 12 12 12 1 WD40-like domain PD40 PF07676.12 KIK51583.1 - 6.5e-13 48.3 2.9 11 6.1 0.0 11.5 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK51583.1 - 3.5e-11 42.6 4.3 0.5 9.3 0.0 10.3 3 2 8 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DsbC_N PF10411.9 KIK51583.1 - 0.00013 21.3 0.1 1.2e+02 2.2 0.0 8.2 10 0 0 10 10 10 0 Disulfide bond isomerase protein N-terminus nos_propeller PF18764.1 KIK51583.1 - 0.0004 20.2 24.8 19 5.2 0.0 11.3 12 1 1 13 13 13 0 Nitrous oxide reductase propeller repeat Ret2_MD PF18528.1 KIK51583.1 - 0.014 15.7 0.0 7.2 7.1 0.0 5.0 4 1 1 5 5 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain AsnC_trans_reg PF01037.21 KIK51583.1 - 0.93 9.5 2.3 1.8e+02 2.2 0.0 5.3 8 0 0 8 8 8 0 Lrp/AsnC ligand binding domain NHL PF01436.21 KIK51583.1 - 1.5 9.0 16.1 77 3.6 0.0 8.4 10 0 0 10 10 10 0 NHL repeat DEAD PF00270.29 KIK51592.1 - 9e-11 41.8 0.1 2.8e-10 40.2 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK51592.1 - 1.9e-10 41.1 0.0 1.2e-09 38.4 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK51592.1 - 0.00078 19.5 0.2 0.0016 18.5 0.2 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIK51592.1 - 0.0086 15.8 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK51592.1 - 0.087 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M76 PF09768.9 KIK51595.1 - 2.9e-66 222.5 2.3 3.5e-66 222.2 2.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family F-box-like PF12937.7 KIK51596.1 - 0.032 14.1 2.2 0.1 12.5 2.2 1.9 1 1 0 1 1 1 0 F-box-like EutH PF04346.12 KIK51597.1 - 0.0047 16.2 0.8 0.0047 16.2 0.8 1.4 2 0 0 2 2 2 1 Ethanolamine utilisation protein, EutH FMO-like PF00743.19 KIK51598.1 - 4.6e-31 107.8 0.0 3e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK51598.1 - 3e-23 82.5 0.0 1.1e-19 70.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK51598.1 - 5.6e-17 61.9 0.1 1e-10 41.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK51598.1 - 8.4e-16 58.0 0.0 8.4e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK51598.1 - 2e-08 34.4 0.9 0.00023 21.2 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KIK51598.1 - 1.1e-07 31.8 0.0 0.1 12.1 0.0 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK51598.1 - 3.6e-06 26.5 0.0 0.021 14.2 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KIK51598.1 - 4.6e-06 26.0 0.9 0.25 10.4 0.1 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK51598.1 - 4.9e-06 26.7 0.0 0.0051 17.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KIK51598.1 - 1.6e-05 25.0 0.0 0.032 14.3 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIK51598.1 - 2.9e-05 23.3 0.0 0.034 13.2 0.0 3.1 4 0 0 4 4 4 2 FAD binding domain FAD_binding_3 PF01494.19 KIK51598.1 - 7.7e-05 22.1 0.4 0.077 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KIK51598.1 - 9.6e-05 22.9 0.1 0.86 10.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK51598.1 - 0.00021 20.5 1.2 0.26 10.3 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 KIK51598.1 - 0.00021 20.6 0.0 0.16 11.1 0.0 3.2 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.18 KIK51598.1 - 0.00054 20.2 0.0 0.087 13.1 0.0 2.6 3 0 0 3 3 2 1 TrkA-N domain F420_oxidored PF03807.17 KIK51598.1 - 0.0051 17.4 0.0 4.2 8.0 0.0 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KIK51598.1 - 0.0067 16.9 0.0 0.92 10.0 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KIK51598.1 - 0.0095 14.7 1.5 0.22 10.2 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KIK51598.1 - 0.015 14.6 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF498 PF04430.14 KIK51598.1 - 0.032 14.3 0.3 0.9 9.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) DUF1188 PF06690.11 KIK51598.1 - 0.06 12.9 0.0 15 5.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1188) ApbA PF02558.16 KIK51598.1 - 0.14 11.8 0.0 3.2 7.4 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA BTB PF00651.31 KIK51599.1 - 7.5e-06 26.2 0.1 1.5e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIK51600.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Glyco_hydro_127 PF07944.12 KIK51601.1 - 1.2e-18 66.9 0.0 2e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 KIK51602.1 - 2.6e-34 118.7 23.4 3.4e-34 118.3 23.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK51603.1 - 8e-34 117.1 22.3 8e-34 117.1 22.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cellulase PF00150.18 KIK51604.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PSS PF03034.15 KIK51605.1 - 1.7e-112 375.7 11.3 2.3e-112 375.2 11.3 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase PET PF06297.14 KIK51605.1 - 0.026 14.8 0.0 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 PET Domain Zn_clus PF00172.18 KIK51606.1 - 1.5e-08 34.6 7.2 3.8e-08 33.3 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KIK51606.1 - 0.026 14.4 0.9 0.85 9.6 0.4 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SelP_N PF04592.14 KIK51606.1 - 9.1 5.6 26.1 1.9 7.8 14.3 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region TANGO2 PF05742.12 KIK51607.1 - 6.1e-46 157.5 0.0 9.7e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Actin PF00022.19 KIK51608.1 - 1.3e-75 254.5 0.0 1.3e-74 251.3 0.0 1.9 1 1 0 1 1 1 1 Actin F-box-like PF12937.7 KIK51609.1 - 0.0011 18.8 1.7 0.0021 17.9 0.7 2.1 2 0 0 2 2 2 1 F-box-like FMO-like PF00743.19 KIK51610.1 - 8.6e-34 116.8 0.0 5.4e-33 114.2 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK51610.1 - 6.1e-25 88.1 0.0 1.5e-21 77.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK51610.1 - 7.6e-17 61.5 0.0 8.8e-13 48.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK51610.1 - 1.8e-16 60.3 0.0 1.4e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK51610.1 - 5.7e-08 32.9 0.6 0.00041 20.4 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 KIK51610.1 - 3.5e-07 29.6 0.4 0.11 11.6 0.0 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 KIK51610.1 - 8.3e-07 28.9 0.0 0.054 13.1 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK51610.1 - 8.3e-07 28.5 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK51610.1 - 8.4e-07 29.1 0.0 0.0065 16.5 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KIK51610.1 - 5.6e-06 26.8 0.1 0.2 12.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK51610.1 - 1.7e-05 24.1 0.3 0.07 12.2 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein TrkA_N PF02254.18 KIK51610.1 - 2.4e-05 24.5 0.0 0.037 14.3 0.0 2.6 3 0 0 3 3 2 2 TrkA-N domain FAD_binding_2 PF00890.24 KIK51610.1 - 2.6e-05 23.5 0.1 0.023 13.8 0.0 3.4 3 1 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KIK51610.1 - 2.7e-05 23.6 0.0 0.08 12.2 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KIK51610.1 - 3.5e-05 23.9 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIK51610.1 - 0.00051 20.5 0.0 0.065 13.7 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.17 KIK51610.1 - 0.001 19.6 0.0 1.7 9.3 0.0 3.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Glu_dehyd_C PF16912.5 KIK51610.1 - 0.0023 17.4 0.0 0.61 9.5 0.0 3.0 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KIK51610.1 - 0.0051 16.1 0.1 1.2 8.3 0.0 2.7 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 KIK51610.1 - 0.0063 15.3 1.5 0.098 11.3 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein DUF498 PF04430.14 KIK51610.1 - 0.023 14.7 0.2 0.59 10.2 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF498/DUF598) ApbA PF02558.16 KIK51610.1 - 0.03 14.0 0.0 1.9 8.1 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.21 KIK51610.1 - 0.05 13.3 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 KIK51610.1 - 0.065 13.1 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 KIK51610.1 - 0.075 12.3 0.0 8.3 5.6 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Staph_opine_DH PF10100.9 KIK51610.1 - 0.077 11.6 0.0 0.76 8.3 0.0 2.0 2 0 0 2 2 2 0 Staphylopine dehydrogenase FMO-like PF00743.19 KIK51611.1 - 1.9e-31 109.1 0.1 5.3e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK51611.1 - 4.2e-23 82.1 0.0 4.9e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK51611.1 - 1.3e-16 60.8 0.0 1.2e-12 47.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK51611.1 - 2.2e-16 60.0 0.2 1.6e-09 37.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK51611.1 - 3.4e-08 33.6 0.3 0.00016 21.7 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KIK51611.1 - 3.9e-07 30.0 0.0 0.079 12.5 0.0 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK51611.1 - 9.8e-07 28.3 0.0 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK51611.1 - 4.3e-06 26.2 0.5 0.01 15.1 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KIK51611.1 - 9.4e-06 24.9 1.2 0.46 9.5 0.2 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK51611.1 - 1e-05 24.8 0.4 0.011 14.9 0.0 3.3 4 0 0 4 4 4 1 FAD binding domain Shikimate_DH PF01488.20 KIK51611.1 - 1.1e-05 25.5 0.1 0.34 11.0 0.1 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KIK51611.1 - 1.4e-05 25.2 0.0 0.018 15.3 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK51611.1 - 2.6e-05 24.7 0.1 0.24 12.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK51611.1 - 6.6e-05 22.1 0.3 0.12 11.5 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein TrkA_N PF02254.18 KIK51611.1 - 0.00037 20.7 0.0 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.17 KIK51611.1 - 0.0014 17.9 0.1 0.2 10.9 0.0 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 KIK51611.1 - 0.0061 17.0 0.0 2.8 8.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KIK51611.1 - 0.0066 15.2 1.1 0.14 10.8 0.0 2.8 4 0 0 4 4 4 1 HI0933-like protein DUF1188 PF06690.11 KIK51611.1 - 0.0079 15.8 0.0 8.8 5.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1188) ApbA PF02558.16 KIK51611.1 - 0.056 13.1 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF498 PF04430.14 KIK51611.1 - 0.06 13.4 0.2 1.6 8.8 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) 3HCDH_N PF02737.18 KIK51611.1 - 0.067 13.1 0.0 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK51611.1 - 0.18 11.1 0.0 0.65 9.2 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_S13_N PF08069.12 KIK51612.1 - 6.2e-31 106.2 0.1 1.3e-30 105.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KIK51612.1 - 3.7e-15 55.9 0.3 4.7e-15 55.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KIK51612.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain ABM PF03992.16 KIK51613.1 - 1.8e-05 24.8 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Spectrin PF00435.21 KIK51613.1 - 0.02 15.4 0.0 0.057 13.9 0.0 1.7 2 0 0 2 2 2 0 Spectrin repeat DUF2306 PF10067.9 KIK51614.1 - 1.2e-10 41.8 5.0 1.2e-10 41.8 5.0 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) TarH PF02203.15 KIK51614.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Pkinase_Tyr PF07714.17 KIK51615.1 - 3.4e-30 105.2 0.0 5.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK51615.1 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain U3snoRNP10 PF12397.8 KIK51616.1 - 0.044 14.1 1.8 0.61 10.4 0.0 2.7 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Proteasom_PSMB PF10508.9 KIK51616.1 - 0.064 11.8 0.0 0.61 8.5 0.1 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 KIK51616.1 - 0.14 12.4 1.6 0.53 10.6 0.5 2.6 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 WSC PF01822.19 KIK51617.1 - 1.6e-25 89.1 24.4 3.3e-15 56.1 11.2 2.4 2 0 0 2 2 2 2 WSC domain Peroxidase_2 PF01328.17 KIK51618.1 - 2.7e-40 138.9 0.0 1.4e-34 120.3 0.0 2.1 1 1 1 2 2 2 2 Peroxidase, family 2 Cation_efflux PF01545.21 KIK51619.1 - 0.72 9.5 10.8 0.12 12.1 1.6 2.4 1 1 1 2 2 2 0 Cation efflux family APG6_N PF17675.1 KIK51622.1 - 0.085 13.4 15.8 4.8 7.7 8.2 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region MAP PF03642.13 KIK51622.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 MAP domain Nas2_N PF18265.1 KIK51622.1 - 0.23 11.4 2.8 11 6.0 0.1 3.7 3 0 0 3 3 3 0 Nas2 N_terminal domain PDDEXK_2 PF12784.7 KIK51622.1 - 0.24 10.9 1.7 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 PD-(D/E)XK nuclease family transposase NRBF2 PF08961.10 KIK51622.1 - 0.31 10.6 6.8 0.051 13.2 2.8 1.7 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator PRKG1_interact PF15898.5 KIK51622.1 - 1.2 10.1 22.1 11 7.0 1.8 3.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc29 PF17082.5 KIK51622.1 - 3.4 7.4 11.5 4.7 7.0 4.6 3.2 2 1 1 3 3 3 0 Spindle Pole Component 29 Uso1_p115_C PF04871.13 KIK51622.1 - 6.2 7.2 11.2 0.88 10.0 5.8 2.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF641 PF04859.12 KIK51622.1 - 7.2 7.0 7.9 1.6 9.1 1.7 2.7 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) betaPIX_CC PF16523.5 KIK51622.1 - 8.7 6.2 11.9 2.6 8.0 0.6 3.4 3 0 0 3 3 3 0 betaPIX coiled coil DUF4281 PF14108.6 KIK51623.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) DUF4419 PF14388.6 KIK51624.1 - 6.6e-114 380.4 0.2 7.8e-114 380.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.6 KIK51625.1 - 1e-111 373.2 0.0 1.2e-111 373.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF1539 PF07560.11 KIK51625.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) MFS_1 PF07690.16 KIK51630.1 - 4.1e-27 95.0 77.6 1.2e-20 73.7 46.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4795 PF16043.5 KIK51631.1 - 0.034 13.8 6.9 0.021 14.4 1.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) Macoilin PF09726.9 KIK51631.1 - 0.41 9.1 15.0 0.58 8.7 15.0 1.1 1 0 0 1 1 1 0 Macoilin family CENP-F_leu_zip PF10473.9 KIK51631.1 - 1.2 9.1 17.2 0.057 13.5 8.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KIK51631.1 - 5.1 7.6 23.9 1.7 9.2 14.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-MYND PF01753.18 KIK51632.1 - 2.1e-05 24.5 6.5 3.7e-05 23.7 6.5 1.4 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 KIK51632.1 - 0.0039 17.5 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) zf-Mss51 PF13824.6 KIK51632.1 - 0.12 12.4 2.5 0.23 11.6 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 GST_N_2 PF13409.6 KIK51633.1 - 2.1e-10 40.7 0.0 6.6e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK51633.1 - 8.5e-10 38.9 0.1 2.8e-09 37.2 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK51633.1 - 0.00017 21.8 0.0 0.0017 18.7 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK51633.1 - 0.0048 17.1 0.0 0.02 15.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK51633.1 - 0.0099 15.9 0.2 0.031 14.3 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK51633.1 - 0.044 14.0 0.3 0.31 11.3 0.0 2.5 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain Trp_halogenase PF04820.14 KIK51634.1 - 3.8e-07 29.3 0.0 5.6e-05 22.2 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KIK51634.1 - 0.0019 18.4 0.0 0.026 14.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain p450 PF00067.22 KIK51635.1 - 3.1e-85 286.7 0.0 3.5e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RB_B PF01857.20 KIK51635.1 - 0.021 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain MFS_1 PF07690.16 KIK51636.1 - 2e-50 171.7 15.3 2e-50 171.7 15.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK51636.1 - 5.3e-10 38.8 0.4 5.3e-10 38.8 0.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KIK51636.1 - 0.015 13.9 19.9 0.0049 15.5 8.7 2.5 2 0 0 2 2 2 0 MFS/sugar transport protein SLATT_fungal PF18142.1 KIK51636.1 - 0.41 10.6 3.2 3 7.9 0.1 2.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Methyltransf_2 PF00891.18 KIK51637.1 - 2.6e-18 66.1 0.0 1e-17 64.1 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KIK51637.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain XFP PF03894.15 KIK51637.1 - 0.038 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Rrf2 PF02082.20 KIK51637.1 - 0.08 13.3 0.0 0.95 9.9 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator Methyltransf_25 PF13649.6 KIK51637.1 - 0.12 13.1 0.0 0.36 11.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK51637.1 - 0.14 13.0 0.0 0.37 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK51637.1 - 0.14 11.9 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF4419 PF14388.6 KIK51638.1 - 1.2e-111 372.9 0.0 1.5e-111 372.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) VCH_CASS14 PF18315.1 KIK51638.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain DUF4139 PF13598.6 KIK51639.1 - 6.5e-21 75.0 0.0 1.8e-20 73.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIK51639.1 - 4.8e-08 33.3 0.2 1.4e-07 31.8 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) zf-H2C2_2 PF13465.6 KIK51640.1 - 0.00012 22.3 2.0 0.00012 22.3 2.0 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK51640.1 - 0.0022 18.4 6.6 0.09 13.3 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK51640.1 - 0.0092 16.7 5.4 0.24 12.4 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2345 PF10106.9 KIK51642.1 - 0.026 14.4 0.8 0.083 12.7 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) CRM1_C PF08767.11 KIK51644.1 - 1.5e-102 343.1 0.0 2.3e-75 253.8 0.0 3.4 3 0 0 3 3 3 2 CRM1 C terminal Xpo1 PF08389.12 KIK51644.1 - 1.3e-38 132.3 5.5 2.2e-37 128.4 3.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIK51644.1 - 1.2e-29 101.7 4.9 2.7e-29 100.6 4.9 1.6 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIK51644.1 - 1.8e-27 95.2 1.0 8.1e-27 93.1 0.6 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIK51644.1 - 8e-17 60.5 3.4 8e-17 60.5 3.4 2.2 3 0 0 3 3 3 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIK51644.1 - 1.5e-14 53.6 0.1 4.3e-14 52.2 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2113 PF09886.9 KIK51644.1 - 0.0043 16.4 0.4 0.075 12.4 0.1 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2113) zf-C2H2 PF00096.26 KIK51645.1 - 9.7e-11 41.5 10.6 4.7e-05 23.6 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK51645.1 - 8.2e-06 26.2 9.6 0.0064 17.2 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK51645.1 - 0.00044 20.5 5.4 0.00044 20.5 5.4 2.6 3 0 0 3 3 3 2 Zinc-finger double domain FOXP-CC PF16159.5 KIK51645.1 - 0.3 11.8 3.5 11 6.8 0.1 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIK51645.1 - 2.7 8.1 8.0 0.33 11.0 0.7 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Carboxyl_trans PF01039.22 KIK51647.1 - 0.13 10.9 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain XPG_I_2 PF12813.7 KIK51647.1 - 0.26 10.8 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 XPG domain containing PQ-loop PF04193.14 KIK51649.1 - 2.3e-16 59.3 9.3 6.3e-12 45.1 0.2 3.3 2 1 0 2 2 2 2 PQ loop repeat Sugar_tr PF00083.24 KIK51650.1 - 5.7e-61 206.7 17.9 1.1e-40 139.9 1.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK51650.1 - 1.6e-18 66.7 37.5 8.9e-16 57.7 26.3 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily ABC2_membrane_2 PF12679.7 KIK51650.1 - 1.3 8.3 9.8 2.9 7.1 9.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.16 KIK51651.1 - 1.1e-28 100.2 32.8 1.6e-28 99.7 32.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.13 KIK51651.1 - 4 7.8 15.2 6.2 7.2 6.3 3.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Pox_F17 PF04767.12 KIK51652.1 - 0.42 11.1 2.3 1.1 9.7 0.5 2.2 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein Syndecan PF01034.20 KIK51655.1 - 0.12 12.3 0.4 0.23 11.4 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain DUF2613 PF11021.8 KIK51655.1 - 4.3 7.5 8.0 3.2 8.0 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) VPDSG-CTERM PF18205.1 KIK51655.1 - 6.3 6.7 10.3 1.6 8.6 4.5 2.7 2 0 0 2 2 2 0 VPDSG-CTERM motif Herpes_gE PF02480.16 KIK51657.1 - 0.025 13.3 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_Coat_B PF05356.11 KIK51657.1 - 0.044 13.7 0.6 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Phage Coat protein B Gram_pos_anchor PF00746.21 KIK51657.1 - 3.3 7.7 5.5 0.62 10.1 0.8 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif F-box-like PF12937.7 KIK51663.1 - 7.8e-08 32.1 2.1 2.2e-07 30.6 2.1 1.8 1 1 0 1 1 1 1 F-box-like DUF3885 PF13021.6 KIK51664.1 - 0.049 13.7 0.5 0.12 12.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) HECT PF00632.25 KIK51665.1 - 6.1e-79 265.7 0.0 7.5e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CLZ PF16526.5 KIK51667.1 - 0.06 13.7 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Amnionless PF14828.6 KIK51667.1 - 0.15 10.9 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless WW PF00397.26 KIK51668.1 - 1.3e-28 98.7 28.1 9.5e-11 41.6 2.8 5.4 5 0 0 5 5 5 4 WW domain C2 PF00168.30 KIK51668.1 - 3.4e-15 56.2 0.0 1.3e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 C2 domain FAM184 PF15665.5 KIK51668.1 - 0.14 11.9 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B CLZ PF16526.5 KIK51668.1 - 0.29 11.5 0.6 0.55 10.6 0.6 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SF1-HH PF16275.5 KIK51668.1 - 0.45 10.9 2.9 0.45 10.9 0.6 2.2 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Syndecan PF01034.20 KIK51670.1 - 0.0054 16.6 2.6 0.01 15.7 2.6 1.4 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 KIK51670.1 - 0.017 16.0 0.0 0.034 15.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KIK51670.1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.10 KIK51670.1 - 0.3 10.5 5.3 0.65 9.5 5.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KIK51672.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family Alpha_GJ PF03229.13 KIK51672.1 - 0.015 15.8 0.6 0.015 15.8 0.6 2.7 1 1 0 2 2 2 0 Alphavirus glycoprotein J Amnionless PF14828.6 KIK51672.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KIK51672.1 - 0.029 13.8 0.3 0.064 12.7 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 KIK51672.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Syndecan PF01034.20 KIK51672.1 - 0.039 13.9 0.2 0.067 13.1 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4381 PF14316.6 KIK51672.1 - 0.073 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PspA_IM30 PF04012.12 KIK51672.1 - 0.14 11.7 0.6 0.21 11.1 0.6 1.1 1 0 0 1 1 1 0 PspA/IM30 family Amnionless PF14828.6 KIK51674.1 - 0.018 13.9 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KIK51674.1 - 6.2 6.3 7.1 0.36 10.3 1.4 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Amnionless PF14828.6 KIK51675.1 - 0.0017 17.3 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 KIK51675.1 - 0.0074 15.7 0.2 0.018 14.4 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KIK51675.1 - 0.05 14.5 0.0 0.14 13.1 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KIK51675.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.9 1 1 1 2 2 2 0 TMEM154 protein family CD34_antigen PF06365.12 KIK51675.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family VHS PF00790.19 KIK51676.1 - 4.5e-32 110.8 0.4 7.3e-32 110.1 0.4 1.3 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.6 KIK51676.1 - 5.4e-16 58.2 0.2 1.3e-15 56.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KIK51676.1 - 2.1e-14 52.8 0.0 5.3e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK51676.1 - 4.4e-12 45.5 0.1 1.2e-11 44.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KIK51676.1 - 8.6e-12 45.2 0.0 2.1e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KIK51676.1 - 0.0013 18.6 4.5 0.0033 17.2 4.5 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif F-box-like PF12937.7 KIK51677.1 - 8.4e-06 25.6 3.1 1.7e-05 24.6 3.1 1.5 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIK51677.1 - 0.048 13.4 1.9 0.13 12.0 0.6 2.5 2 0 0 2 2 2 0 Leucine rich repeat DUF5445 PF17520.2 KIK51677.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5445) Amnionless PF14828.6 KIK51678.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless Trp_oprn_chp PF09534.10 KIK51678.1 - 0.026 14.3 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 KIK51678.1 - 0.16 12.9 0.0 0.28 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK51679.1 - 3e-05 23.1 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 KIK51679.1 - 0.0091 15.4 1.9 0.022 14.2 1.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sulf_transp PF04143.14 KIK51679.1 - 0.027 14.1 0.8 0.037 13.6 0.8 1.2 1 0 0 1 1 1 0 Sulphur transport EphA2_TM PF14575.6 KIK51679.1 - 0.034 15.0 0.0 0.077 13.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KIK51679.1 - 0.044 13.6 0.6 0.044 13.6 0.6 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 UvrB PF12344.8 KIK51679.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Ultra-violet resistance protein B RIFIN PF02009.16 KIK51679.1 - 0.2 11.5 0.4 2.1 8.2 0.4 2.1 1 1 1 2 2 2 0 Rifin Podoplanin PF05808.11 KIK51679.1 - 0.23 11.6 16.6 0.02 15.0 11.1 2.0 2 1 1 3 3 3 0 Podoplanin Tmemb_cc2 PF10267.9 KIK51679.1 - 0.74 8.9 4.1 2.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Piwi PF02171.17 KIK51680.1 - 1.7e-79 267.2 0.0 2.4e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK51680.1 - 1.7e-12 48.1 0.0 5.2e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KIK51680.1 - 4.5e-09 36.5 0.0 1.3e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KIK51680.1 - 3.2e-06 26.7 0.0 1e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain NmrA PF05368.13 KIK51682.1 - 4.6e-27 95.1 0.0 7.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK51682.1 - 6.1e-11 42.5 0.0 8.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 KIK51682.1 - 0.0052 16.3 0.0 0.025 14.1 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIK51682.1 - 0.016 14.4 0.0 7.4 5.6 0.0 2.6 3 1 0 3 3 3 0 Male sterility protein ArgoL2 PF16488.5 KIK51683.1 - 0.017 15.5 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Argonaute linker 2 domain Sporozoite_P67 PF05642.11 KIK51684.1 - 0.53 8.3 13.0 0.74 7.8 13.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KIK51684.1 - 0.83 7.9 12.1 1 7.6 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KIK51684.1 - 1.4 6.9 11.3 1.8 6.6 11.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KIK51684.1 - 3.7 6.2 11.6 4.8 5.8 11.6 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 KIK51684.1 - 6.1 5.1 10.8 7.9 4.7 10.8 1.1 1 0 0 1 1 1 0 Menin Mre11_DNA_bind PF04152.14 KIK51684.1 - 8.5 6.7 11.5 0.74 10.1 3.9 2.3 1 1 1 2 2 2 0 Mre11 DNA-binding presumed domain DUF444 PF04285.12 KIK51685.1 - 0.0085 15.2 0.2 0.0096 15.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF444) APP_E2 PF12925.7 KIK51685.1 - 0.0094 15.7 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein S-antigen PF05756.11 KIK51686.1 - 0.089 13.2 3.1 0.091 13.1 0.2 2.0 2 0 0 2 2 2 0 S-antigen protein DUF953 PF06110.11 KIK51687.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) RPA43_OB PF17875.1 KIK51690.1 - 0.067 13.8 1.6 0.067 13.8 1.6 1.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MPP6 PF10175.9 KIK51690.1 - 0.083 13.4 5.4 1.3 9.5 2.0 2.2 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Astro_capsid_p PF12226.8 KIK51690.1 - 0.28 10.3 2.2 0.38 9.9 2.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 KIK51690.1 - 0.63 10.1 5.5 0.19 11.8 1.4 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.6 KIK51690.1 - 2.1 8.6 11.1 1.7 8.9 8.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 KIK51690.1 - 4.2 7.0 10.2 1.1 8.9 4.7 2.1 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 KIK51690.1 - 6.1 4.8 14.1 10 4.1 14.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi PKcGMP_CC PF16808.5 KIK51692.1 - 0.0017 18.2 4.5 0.4 10.6 0.7 2.6 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK51692.1 - 0.01 15.9 0.4 0.017 15.2 0.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mlo PF03094.15 KIK51692.1 - 0.021 13.3 0.2 0.033 12.6 0.2 1.2 1 0 0 1 1 1 0 Mlo family HMMR_N PF15905.5 KIK51692.1 - 0.022 14.3 8.0 0.031 13.8 8.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK51692.1 - 0.27 10.1 8.1 0.41 9.5 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 KIK51692.1 - 1.6 9.1 8.1 27 5.1 8.1 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 KIK51692.1 - 2.2 8.7 10.9 0.45 10.9 0.8 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF745 PF05335.13 KIK51693.1 - 0.062 13.0 3.7 1.2 8.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Retrotrans_gag PF03732.17 KIK51696.1 - 0.0049 17.1 0.0 0.0099 16.1 0.0 1.5 1 1 1 2 2 2 1 Retrotransposon gag protein KDZ PF18758.1 KIK51699.1 - 7.1e-08 32.3 0.1 1.2e-07 31.6 0.1 1.3 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK51700.1 - 1.1e-24 87.2 0.7 1.5e-24 86.9 0.7 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Dimer_Tnp_hAT PF05699.14 KIK51703.1 - 3.3e-09 36.4 0.1 7.3e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK51703.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Med8 PF10232.9 KIK51704.1 - 0.073 12.6 0.1 0.077 12.6 0.1 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF2196 PF09962.9 KIK51706.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) TcpQ PF10671.9 KIK51706.1 - 0.26 11.4 0.7 3.3 7.9 0.1 2.7 2 1 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q RicinB_lectin_2 PF14200.6 KIK51708.1 - 0.021 15.6 0.0 0.031 15.0 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like zf-RVT PF13966.6 KIK51710.1 - 0.00023 21.8 1.6 0.00023 21.8 1.6 2.7 2 1 0 2 2 2 2 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK51711.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Calc_CGRP_IAPP PF00214.19 KIK51712.1 - 2.4 8.5 4.5 4.7 7.6 2.3 2.3 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family HILPDA PF15220.6 KIK51714.1 - 0.12 12.6 0.9 0.22 11.6 0.9 1.5 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated TACC_C PF05010.14 KIK51716.1 - 0.015 15.1 0.9 0.019 14.8 0.9 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF745 PF05335.13 KIK51716.1 - 0.036 13.8 4.5 0.84 9.3 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.19 KIK51716.1 - 0.15 9.9 0.1 0.17 9.8 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RicinB_lectin_2 PF14200.6 KIK51719.1 - 2.4e-05 25.0 0.9 0.00078 20.1 0.7 2.1 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like zf-CCHC PF00098.23 KIK51720.1 - 0.0043 17.1 5.9 0.0043 17.1 5.9 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIK51720.1 - 0.059 13.2 7.6 0.059 13.2 7.6 2.0 2 0 0 2 2 2 0 Zinc knuckle COMPASS-Shg1 PF05205.12 KIK51722.1 - 0.12 13.1 0.1 0.8 10.4 0.1 2.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Cript PF10235.9 KIK51722.1 - 0.33 11.5 7.8 0.96 10.1 7.8 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT ApoLp-III PF07464.11 KIK51722.1 - 0.56 10.3 5.7 7.2 6.7 1.0 3.4 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PMC2NT PF08066.12 KIK51722.1 - 4.1 8.1 5.3 1.3e+02 3.4 0.1 4.6 5 0 0 5 5 5 0 PMC2NT (NUC016) domain RNF111_N PF15303.6 KIK51723.1 - 0.12 12.1 1.2 0.12 12.1 1.2 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus WD40 PF00400.32 KIK51727.1 - 1.1e-108 352.0 60.8 3.6e-09 37.1 0.2 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51727.1 - 2.3e-29 101.5 16.3 0.0016 18.7 0.0 11.6 1 1 11 13 13 13 8 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK51727.1 - 1.1e-14 53.7 0.5 0.082 11.2 0.0 7.9 3 2 3 8 8 8 4 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK51727.1 - 1.1e-11 44.6 7.5 0.84 8.9 0.0 7.2 3 2 3 8 8 8 5 WD40-like domain PQQ_2 PF13360.6 KIK51727.1 - 1e-10 41.7 19.1 0.00041 20.0 6.4 5.6 1 1 4 5 5 5 4 PQQ-like domain Ge1_WD40 PF16529.5 KIK51727.1 - 1.4e-10 40.7 13.4 0.043 12.8 0.0 9.5 2 2 8 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK51727.1 - 3e-10 40.3 0.0 6.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK51727.1 - 5e-07 30.3 0.0 1.9e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Me-amine-dh_H PF06433.11 KIK51727.1 - 3.6e-05 22.8 1.3 0.5 9.2 0.1 5.1 3 1 3 8 8 8 2 Methylamine dehydrogenase heavy chain (MADH) AAA PF00004.29 KIK51727.1 - 0.00018 22.0 0.0 0.00052 20.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KIK51727.1 - 0.00025 20.9 12.5 15 5.7 0.0 9.0 11 0 0 11 11 10 0 WD40-like Beta Propeller Repeat NB-ARC PF00931.22 KIK51727.1 - 0.00046 19.5 0.1 0.0021 17.3 0.0 2.2 2 1 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 KIK51727.1 - 0.0014 19.0 0.6 0.049 14.0 0.0 3.8 4 0 0 4 4 4 1 RNA helicase Cytochrom_D1 PF02239.16 KIK51727.1 - 0.0016 17.1 8.6 1.8 7.0 0.0 5.1 1 1 4 6 6 6 2 Cytochrome D1 heme domain ABC_tran PF00005.27 KIK51727.1 - 0.0046 17.5 0.0 0.015 15.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KIK51727.1 - 0.0076 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIK51727.1 - 0.017 14.3 0.0 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 KIK51727.1 - 0.027 14.8 0.0 0.093 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK51727.1 - 0.03 14.3 0.1 0.24 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK51727.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PQQ_3 PF13570.6 KIK51727.1 - 0.32 11.5 11.4 42 4.8 0.0 7.4 9 0 0 9 9 7 0 PQQ-like domain eIF2A PF08662.11 KIK51730.1 - 2.9e-77 258.9 0.0 5.9e-77 257.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KIK51730.1 - 0.087 13.7 0.4 0.93 10.5 0.1 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 KIK51731.1 - 6.4e-10 40.0 0.0 1.1e-09 39.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK51731.1 - 5.3e-06 26.3 0.0 5.9e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK51731.1 - 0.0032 16.8 0.0 0.028 13.7 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK51732.1 - 3e-11 44.4 1.8 4e-11 43.9 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK51732.1 - 4.5e-06 26.5 0.0 9e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK51732.1 - 0.001 18.4 0.0 0.013 14.8 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KIK51732.1 - 0.038 13.6 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase Peptidase_S28 PF05577.12 KIK51732.1 - 0.096 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PGAP1 PF07819.13 KIK51732.1 - 0.21 11.3 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein VPS13 PF16908.5 KIK51733.1 - 3.1e-05 23.9 1.2 7.2e-05 22.7 1.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal HlyIII PF03006.20 KIK51738.1 - 1.7e-46 158.8 27.6 2e-46 158.5 27.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related VPS13 PF16908.5 KIK51740.1 - 7.8e-05 22.6 1.8 0.00016 21.6 1.8 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal ASD2 PF08687.11 KIK51741.1 - 0.027 14.0 0.1 0.032 13.8 0.1 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Smg8_Smg9 PF10220.9 KIK51741.1 - 0.17 10.1 0.7 0.19 10.0 0.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Cyclase PF04199.13 KIK51743.1 - 2.4e-15 57.0 0.0 3.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase HA2 PF04408.23 KIK51744.1 - 0.047 14.0 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) Terpene_synth_C PF03936.16 KIK51745.1 - 1.2e-07 31.4 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIK51745.1 - 0.0039 16.1 0.3 0.0074 15.2 0.3 1.4 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) PP2C PF00481.21 KIK51747.1 - 0.00027 20.6 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Arm_vescicular PF18770.1 KIK51747.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Calici_PP_N PF08405.11 KIK51747.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal PP2C PF00481.21 KIK51748.1 - 1.3e-35 123.3 0.0 1.6e-34 119.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIK51748.1 - 1.8e-05 24.7 0.0 0.28 11.1 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) MFS_1 PF07690.16 KIK51749.1 - 1.1e-41 142.9 54.1 8.5e-41 140.0 53.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK51749.1 - 1.7e-09 37.1 8.3 1.7e-09 37.1 8.3 3.4 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIK51749.1 - 5.6e-08 31.7 14.0 5.1e-07 28.5 13.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pam17 PF08566.10 KIK51749.1 - 0.43 10.4 1.3 1.2 8.9 0.4 2.1 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 NADH-G_4Fe-4S_3 PF10588.9 KIK51750.1 - 0.13 11.8 6.3 0.43 10.2 2.4 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region VP_N-CPKC PF11475.8 KIK51750.1 - 0.52 10.3 6.0 0.61 10.0 0.1 2.3 2 0 0 2 2 2 0 Virion protein N terminal domain Cas_DxTHG PF09455.10 KIK51751.1 - 0.0037 16.9 4.2 0.0042 16.7 4.2 1.0 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family CENP-H PF05837.12 KIK51751.1 - 0.16 12.4 11.4 0.2 12.1 11.4 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Borrelia_P83 PF05262.11 KIK51751.1 - 0.45 8.9 11.8 0.46 8.9 11.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Effector_1 PF04518.12 KIK51751.1 - 0.8 8.7 7.6 0.92 8.5 7.6 1.0 1 0 0 1 1 1 0 Effector from type III secretion system DUF3987 PF13148.6 KIK51751.1 - 1.4 7.8 9.4 1.7 7.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Csm1_N PF18504.1 KIK51751.1 - 2.1 8.7 10.7 6.5 7.2 10.6 1.8 1 1 0 1 1 1 0 Csm1 N-terminal domain Hydin_ADK PF17213.3 KIK51751.1 - 6.1 7.1 11.4 7.2 6.8 11.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Yip1 PF04893.17 KIK51752.1 - 0.0095 15.7 1.3 0.012 15.3 1.3 1.2 1 0 0 1 1 1 1 Yip1 domain DUF3937 PF13073.6 KIK51752.1 - 0.029 14.5 0.3 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) EI24 PF07264.11 KIK51752.1 - 0.038 14.2 3.8 0.047 13.9 3.8 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF805 PF05656.14 KIK51752.1 - 0.099 13.1 0.7 0.16 12.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DHHC PF01529.20 KIK51752.1 - 0.099 12.7 2.2 0.17 12.0 2.2 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF2207 PF09972.9 KIK51752.1 - 0.28 9.9 0.7 0.32 9.7 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Shugoshin_C PF07557.11 KIK51753.1 - 8.8e-09 35.0 4.3 8.8e-09 35.0 4.3 3.6 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.11 KIK51753.1 - 4e-08 33.0 2.5 8.7e-08 31.9 2.5 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 KIK51753.1 - 0.097 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KIK51753.1 - 2.8 7.8 4.6 1.1 9.1 1.3 2.0 2 0 0 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.6 KIK51753.1 - 5.2 6.6 8.2 0.069 12.7 0.4 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Peptidase_C37 PF05416.12 KIK51753.1 - 8.4 4.8 9.3 1.5 7.3 1.9 2.1 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Glyco_hydro_31 PF01055.26 KIK51755.1 - 2.4e-149 498.3 2.1 3e-149 498.0 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK51755.1 - 5e-37 126.6 0.1 9.6e-37 125.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK51755.1 - 6.3e-13 48.8 2.2 1.4e-12 47.7 0.7 2.5 2 1 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KIK51755.1 - 0.031 14.5 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Tail_VII PF17091.5 KIK51759.1 - 0.21 11.5 0.6 29 4.7 0.0 3.3 3 0 0 3 3 3 0 Inovirus G7P protein Phage_spike PF18715.1 KIK51759.1 - 0.94 9.6 10.4 39 4.4 4.3 4.4 4 1 0 4 4 4 0 Phage spike trimer XRN1_DBM PF18245.1 KIK51759.1 - 6 7.0 6.4 86 3.3 0.1 4.3 5 0 0 5 5 5 0 5-3 exonuclease XRN1 DCP1-binding motif UN_NPL4 PF11543.8 KIK51760.1 - 0.036 14.5 0.0 13 6.4 0.0 2.6 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 DUF1720 PF08226.11 KIK51760.1 - 0.16 12.4 3.7 0.38 11.2 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) SNF2_N PF00176.23 KIK51761.1 - 6.1e-22 77.8 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK51761.1 - 1e-12 48.3 0.1 5e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK51761.1 - 0.00051 19.3 0.2 0.00092 18.5 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_16 PF13191.6 KIK51763.1 - 0.00037 20.9 0.0 0.00073 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK51763.1 - 0.0095 14.9 0.1 0.016 14.1 0.0 1.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KIK51763.1 - 0.03 14.6 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK51763.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 KIK51763.1 - 0.085 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KIK51763.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 KIK51763.1 - 0.2 11.3 0.2 0.32 10.6 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Aldedh PF00171.22 KIK51764.1 - 5.5e-63 213.1 0.0 1.6e-62 211.5 0.0 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family NACHT PF05729.12 KIK51766.1 - 8.3e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK51766.1 - 0.0062 16.9 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KIK51766.1 - 0.0072 16.7 0.0 0.0083 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK51766.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.3 1 1 0 1 1 1 0 NTPase AAA_23 PF13476.6 KIK51766.1 - 0.03 14.8 0.0 0.031 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK51766.1 - 0.032 14.8 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK51766.1 - 0.04 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIK51766.1 - 0.044 13.9 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK51766.1 - 0.053 12.7 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KIK51766.1 - 0.074 13.5 0.0 0.086 13.3 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK51766.1 - 0.081 13.2 0.0 0.085 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK51766.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIK51766.1 - 0.095 11.8 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK51766.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 KIK51766.1 - 0.21 11.3 0.1 0.29 10.9 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KIK51766.1 - 0.22 11.2 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK51768.1 - 1.1e-106 345.7 44.5 3.4e-10 40.3 0.2 12.6 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK51768.1 - 1.6e-44 150.1 1.4 0.0065 16.7 0.0 11.8 2 2 10 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK51768.1 - 1.3e-42 145.9 15.1 0.00065 18.8 0.0 11.9 3 3 9 12 12 12 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK51768.1 - 2.3e-21 75.2 15.0 0.82 9.7 0.1 12.1 12 0 0 12 12 12 7 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK51768.1 - 1.6e-15 56.8 18.8 0.57 8.7 0.1 10.7 6 4 4 11 11 11 6 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK51768.1 - 5.3e-13 49.3 0.4 0.00038 20.4 0.1 5.1 2 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK51768.1 - 7.6e-12 45.1 16.2 0.23 10.7 0.0 10.7 1 1 11 12 12 12 3 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK51768.1 - 6e-09 36.0 23.0 0.0006 19.7 2.7 6.9 2 2 3 5 5 5 3 Lipoprotein LpqB beta-propeller domain WD40_3 PF15911.5 KIK51768.1 - 2.2e-05 24.3 2.5 4.1 7.5 0.0 7.5 9 0 0 9 9 8 1 WD domain, G-beta repeat Peptidase_S9_N PF02897.15 KIK51768.1 - 8.5e-05 21.5 0.1 7.1 5.3 0.0 5.4 2 2 3 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DHFR_2 PF06442.11 KIK51768.1 - 0.00013 21.8 2.6 3.7 7.5 0.1 6.4 5 2 2 7 7 7 1 R67 dihydrofolate reductase DUF3748 PF12566.8 KIK51768.1 - 0.00037 20.4 3.6 5.9 6.9 0.0 7.1 8 1 1 9 9 9 1 Protein of unknown function (DUF3748) DUF3261 PF11659.8 KIK51768.1 - 0.00054 19.8 0.0 55 3.6 0.0 6.7 8 2 1 10 10 10 0 Protein of unknown function (DUF3261) Frtz PF11768.8 KIK51768.1 - 0.0031 15.9 0.0 3.4 5.9 0.0 3.3 2 2 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PsbN PF02468.15 KIK51768.1 - 0.024 14.5 0.4 27 4.7 0.0 3.9 5 0 0 5 5 3 0 Photosystem II reaction centre N protein (psbN) TruB_C PF09142.11 KIK51768.1 - 0.03 14.1 0.9 30 4.5 0.0 5.3 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal IKI3 PF04762.12 KIK51768.1 - 0.099 10.6 0.0 20 3.0 0.0 3.6 3 1 0 4 4 4 0 IKI3 family DUF4596 PF15363.6 KIK51768.1 - 0.13 12.5 0.3 0.13 12.5 0.3 5.9 7 0 0 7 7 6 0 Domain of unknown function (DUF4596) Proteasome_A_N PF10584.9 KIK51768.1 - 5.5 6.8 36.8 24 4.7 0.1 11.0 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 KIK51770.1 - 2.1e-08 33.5 0.7 2.5e-08 33.2 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.22 KIK51771.1 - 0.016 13.7 0.0 0.018 13.6 0.0 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Aldedh PF00171.22 KIK51772.1 - 4.9e-11 41.8 0.0 5.1e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_16 PF13191.6 KIK51773.1 - 0.0068 16.8 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK51773.1 - 0.038 12.9 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KIK51773.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Aldedh PF00171.22 KIK51774.1 - 3.4e-33 114.9 0.0 1.8e-29 102.6 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Tannase PF07519.11 KIK51775.1 - 3.9e-65 220.6 1.0 1.5e-54 185.7 0.0 3.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase MMS22L_C PF14911.6 KIK51776.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal Xpo1 PF08389.12 KIK51776.1 - 0.14 12.2 2.2 2 8.5 0.3 2.3 1 1 1 2 2 2 0 Exportin 1-like protein APG12 PF04110.13 KIK51777.1 - 9.5e-13 48.4 0.1 1.6e-12 47.7 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF5325 PF17259.2 KIK51778.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Aldedh PF00171.22 KIK51779.1 - 7.3e-54 183.0 0.0 8.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_10 PF13374.6 KIK51781.1 - 6.9e-67 219.7 3.1 5.4e-08 32.5 0.0 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK51781.1 - 4.1e-59 196.8 17.9 4.1e-10 39.8 0.1 7.9 1 1 8 9 9 9 9 Tetratricopeptide repeat Aldedh PF00171.22 KIK51781.1 - 3.9e-20 71.8 0.0 1.8e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 Aldehyde dehydrogenase family TPR_7 PF13176.6 KIK51781.1 - 7e-08 32.0 14.9 0.51 10.5 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK51781.1 - 1.2e-06 28.9 0.8 0.38 11.3 0.0 5.7 4 2 1 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 KIK51781.1 - 3.4e-06 26.4 0.0 1.3e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 KIK51781.1 - 3.6e-06 27.1 2.6 4.6 7.5 0.0 6.2 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIK51781.1 - 6.6e-06 25.8 17.6 3.8 7.8 0.0 9.1 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK51781.1 - 2.9e-05 23.7 18.3 1.6 8.6 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK51781.1 - 3.9e-05 23.2 3.1 0.011 15.1 0.0 3.5 1 1 3 4 4 4 1 MalT-like TPR region Rapsyn_N PF10579.9 KIK51781.1 - 6.6e-05 22.9 0.6 10 6.3 0.0 6.1 5 3 2 7 7 6 0 Rapsyn N-terminal myristoylation and linker region PPR PF01535.20 KIK51781.1 - 0.00011 22.2 5.4 45 4.6 0.0 7.6 8 0 0 8 8 7 0 PPR repeat TPR_8 PF13181.6 KIK51781.1 - 0.00036 20.5 7.4 3.5 8.1 0.0 6.2 7 0 0 7 7 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 KIK51781.1 - 0.00061 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF3856 PF12968.7 KIK51781.1 - 0.003 17.6 0.6 53 3.9 0.0 5.0 1 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 KIK51781.1 - 0.004 17.6 0.0 49 5.0 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3400 PF11880.8 KIK51781.1 - 0.005 16.3 0.1 1.2e+02 2.3 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3400) Fis1_TPR_C PF14853.6 KIK51781.1 - 0.028 14.5 3.6 76 3.5 0.0 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF2664 PF10867.8 KIK51781.1 - 0.04 14.4 0.6 5.8 7.4 0.0 4.2 5 0 0 5 5 4 0 Protein of unknown function (DUF2664) TPR_14 PF13428.6 KIK51781.1 - 0.066 14.1 0.3 24 6.1 0.0 4.8 5 0 0 5 5 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 KIK51781.1 - 0.092 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Vps39_1 PF10366.9 KIK51781.1 - 0.39 11.0 2.8 3.8 7.8 0.0 3.9 3 2 2 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_17 PF13431.6 KIK51781.1 - 0.89 10.1 4.0 80 4.0 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK51782.1 - 2.4e-72 237.0 6.0 1.5e-08 34.2 0.0 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK51782.1 - 3.9e-64 212.9 20.6 1.2e-11 44.7 0.1 7.9 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KIK51782.1 - 3.6e-13 48.5 21.1 0.16 12.0 0.1 9.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51782.1 - 4.7e-12 45.1 10.7 1.8 8.9 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK51782.1 - 4.4e-10 38.9 22.1 0.11 12.4 0.1 8.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK51782.1 - 2.5e-09 37.5 1.8 4.3 7.9 0.0 6.0 4 1 2 6 6 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK51782.1 - 6.9e-09 35.7 0.6 1.2 9.3 0.0 7.0 3 3 4 7 7 7 1 Rapsyn N-terminal myristoylation and linker region TPR_2 PF07719.17 KIK51782.1 - 1.2e-08 34.4 21.1 0.43 10.8 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat Zincin_2 PF10103.9 KIK51782.1 - 5.9e-07 29.1 0.1 0.013 14.8 0.0 3.3 2 2 0 2 2 2 2 Zincin-like metallopeptidase ANAPC3 PF12895.7 KIK51782.1 - 2.2e-06 27.8 0.1 1.9 8.8 0.0 5.1 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KIK51782.1 - 1.6e-05 25.1 0.0 2.2 9.2 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK51782.1 - 3.6e-05 23.3 5.2 0.18 11.1 0.5 4.3 1 1 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 KIK51782.1 - 4.1e-05 24.1 0.5 3.1 8.5 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK51782.1 - 0.00016 22.2 0.4 11 7.2 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK51782.1 - 0.00017 21.8 0.1 65 4.0 0.0 6.3 5 2 2 7 7 7 0 Tetratricopeptide repeat MCPVI PF02993.14 KIK51782.1 - 0.00018 21.4 1.9 3.4 7.4 0.0 5.0 1 1 2 5 5 5 1 Minor capsid protein VI TPR_9 PF13371.6 KIK51782.1 - 0.00094 19.3 0.5 17 5.6 0.0 5.0 4 1 2 6 6 6 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KIK51782.1 - 0.0026 18.0 5.8 0.089 13.1 0.1 4.3 2 1 3 5 5 5 1 Vacuolar sorting protein 39 domain 1 DUF3400 PF11880.8 KIK51782.1 - 0.0033 16.9 0.3 67 3.1 0.0 5.7 7 0 0 7 7 6 0 Domain of unknown function (DUF3400) PPR PF01535.20 KIK51782.1 - 0.0047 17.1 0.6 42 4.7 0.0 5.8 7 0 0 7 7 6 0 PPR repeat TPR_6 PF13174.6 KIK51782.1 - 0.0076 16.8 4.7 1.1e+02 3.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK51782.1 - 0.0077 15.9 4.0 23 4.7 0.1 4.9 4 0 0 4 4 4 0 TPR repeat BTAD PF03704.17 KIK51782.1 - 0.012 16.1 2.4 9.9 6.6 0.0 4.2 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Titin_Ig-rpts PF06582.12 KIK51782.1 - 0.014 15.3 2.5 93 3.1 0.0 6.0 6 0 0 6 6 6 0 Titin repeat DUF4919 PF16266.5 KIK51782.1 - 0.048 13.6 4.4 21 5.0 0.1 5.1 3 2 2 6 6 6 0 Domain of unknown function (DUF4919) TPR_17 PF13431.6 KIK51782.1 - 3.2 8.3 26.2 8.8 7.0 0.1 7.3 9 0 0 9 9 7 0 Tetratricopeptide repeat Aldedh PF00171.22 KIK51783.1 - 0.0002 20.0 0.0 0.00024 19.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DNA_pol_A_exo1 PF01612.20 KIK51784.1 - 1.8e-07 31.0 0.1 3.5e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease MMS22L_C PF14911.6 KIK51785.1 - 0.036 13.2 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Anticodon_1 PF08264.13 KIK51785.1 - 0.046 13.7 0.2 0.071 13.1 0.2 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Xpo1 PF08389.12 KIK51785.1 - 0.057 13.5 2.4 1.1 9.4 0.3 2.1 1 1 1 2 2 2 0 Exportin 1-like protein APG12 PF04110.13 KIK51786.1 - 7.9e-05 23.0 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Aldedh PF00171.22 KIK51788.1 - 2e-53 181.6 0.1 1.1e-42 146.2 0.1 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family TPR_10 PF13374.6 KIK51789.1 - 7.4e-72 235.5 6.1 7e-08 32.1 0.1 9.5 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK51789.1 - 1.1e-63 211.4 20.3 1.3e-10 41.4 0.4 8.6 2 1 9 11 11 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 KIK51789.1 - 1.2e-09 37.6 17.9 0.45 10.8 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK51789.1 - 1.9e-09 36.9 16.1 1.1 9.5 0.0 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51789.1 - 4.2e-09 35.9 7.1 3.4 8.1 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK51789.1 - 1.2e-08 34.9 0.6 0.34 11.0 0.0 7.0 3 3 4 7 7 7 1 Rapsyn N-terminal myristoylation and linker region ANAPC3 PF12895.7 KIK51789.1 - 3.2e-08 33.7 0.0 0.018 15.3 0.0 4.9 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIK51789.1 - 4.4e-08 32.6 16.8 0.082 12.8 0.1 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK51789.1 - 6.8e-08 32.9 1.9 1.9 9.1 0.0 6.6 5 1 3 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK51789.1 - 3.5e-07 30.2 0.7 10 7.1 0.0 6.5 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK51789.1 - 8e-07 28.7 1.1 0.0017 17.8 0.1 3.0 1 1 1 2 2 2 2 MalT-like TPR region PPR PF01535.20 KIK51789.1 - 1.9e-05 24.6 3.4 35 5.0 0.0 7.0 8 0 0 8 8 7 0 PPR repeat MCPVI PF02993.14 KIK51789.1 - 2.3e-05 24.3 1.2 7 6.4 0.0 5.5 1 1 3 5 5 5 0 Minor capsid protein VI SRP_TPR_like PF17004.5 KIK51789.1 - 9.8e-05 22.4 0.2 8.1 6.5 0.0 5.5 3 1 2 5 5 5 0 Putative TPR-like repeat DUF3856 PF12968.7 KIK51789.1 - 0.00042 20.4 1.5 5.9 6.9 0.1 5.4 3 1 3 6 6 6 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 KIK51789.1 - 0.0024 18.5 2.9 1e+02 3.6 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KIK51789.1 - 0.0055 17.0 2.5 0.45 10.8 0.1 4.1 3 1 2 5 5 5 1 Vacuolar sorting protein 39 domain 1 Zincin_2 PF10103.9 KIK51789.1 - 0.008 15.5 0.0 0.28 10.4 0.0 2.9 2 2 1 3 3 3 1 Zincin-like metallopeptidase DUF3400 PF11880.8 KIK51789.1 - 0.0086 15.6 0.2 73 3.0 0.0 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF3400) TPR_14 PF13428.6 KIK51789.1 - 0.0095 16.7 1.5 15 6.8 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF2664 PF10867.8 KIK51789.1 - 0.012 16.0 1.5 26 5.3 0.0 5.1 6 1 1 7 7 6 0 Protein of unknown function (DUF2664) DUF4919 PF16266.5 KIK51789.1 - 0.016 15.1 2.1 7.2 6.5 0.1 4.6 4 2 2 6 6 6 0 Domain of unknown function (DUF4919) TPR_6 PF13174.6 KIK51789.1 - 0.022 15.4 1.1 56 4.7 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KIK51789.1 - 0.027 14.0 1.0 55 3.2 0.0 4.3 5 1 0 5 5 5 0 Foie gras liver health family 1 BTAD PF03704.17 KIK51789.1 - 0.043 14.2 3.4 9 6.7 0.1 4.5 2 1 3 5 5 5 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 KIK51789.1 - 0.066 13.3 4.6 26 5.0 0.0 5.2 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat SCP2_2 PF13530.6 KIK51789.1 - 0.069 13.6 0.1 29 5.1 0.0 4.6 3 2 2 5 5 4 0 Sterol carrier protein domain RIG-I_C PF18119.1 KIK51789.1 - 0.085 12.9 0.8 2.5 8.1 0.1 3.3 2 2 1 3 3 3 0 RIG-I receptor C-terminal domain TPR_11 PF13414.6 KIK51789.1 - 1.4 8.7 10.5 62 3.4 0.0 6.0 7 0 0 7 7 6 0 TPR repeat BESS PF02944.20 KIK51790.1 - 0.11 12.3 0.1 0.38 10.6 0.1 2.0 1 0 0 1 1 1 0 BESS motif GntR PF00392.21 KIK51790.1 - 0.12 12.0 0.2 0.92 9.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KIK51790.1 - 0.17 12.0 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_10 PF13374.6 KIK51792.1 - 2.6e-71 233.8 2.1 6.7e-08 32.2 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK51792.1 - 8e-65 215.1 24.3 1.3e-11 44.6 0.1 8.0 1 1 8 9 9 9 9 Tetratricopeptide repeat Aldedh PF00171.22 KIK51792.1 - 2.2e-17 62.8 0.0 3.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_7 PF13176.6 KIK51792.1 - 1.9e-09 36.9 18.2 0.55 10.4 0.0 8.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK51792.1 - 3.7e-07 29.7 16.9 0.61 10.0 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51792.1 - 5.5e-07 29.3 6.6 2.5 8.5 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK51792.1 - 6.9e-07 29.3 0.1 0.43 10.7 0.0 6.7 6 1 1 7 7 7 1 Rapsyn N-terminal myristoylation and linker region TPR_19 PF14559.6 KIK51792.1 - 2.8e-06 27.8 0.0 4 8.0 0.0 5.0 3 2 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK51792.1 - 4e-06 27.0 0.9 1.1 9.5 0.0 5.2 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 KIK51792.1 - 7e-05 22.1 0.1 0.0002 20.6 0.1 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 KIK51792.1 - 8.4e-05 22.1 0.3 0.0097 15.3 0.1 3.1 2 1 1 3 3 3 1 MalT-like TPR region TPR_2 PF07719.17 KIK51792.1 - 0.00019 21.3 20.4 3 8.2 0.1 8.6 10 0 0 10 10 8 1 Tetratricopeptide repeat Zincin_2 PF10103.9 KIK51792.1 - 0.0013 18.1 0.0 0.42 9.8 0.0 2.8 2 1 1 3 3 3 1 Zincin-like metallopeptidase AAA_16 PF13191.6 KIK51792.1 - 0.0044 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_4 PF07721.14 KIK51792.1 - 0.0064 17.0 0.0 33 5.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK51792.1 - 0.012 16.2 0.9 5.4 7.7 0.2 4.2 5 0 0 5 5 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 KIK51792.1 - 0.025 14.9 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain PPR PF01535.20 KIK51792.1 - 0.068 13.4 0.2 51 4.4 0.0 4.9 5 0 0 5 5 4 0 PPR repeat TPR_17 PF13431.6 KIK51792.1 - 0.073 13.5 6.5 19 5.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KIK51792.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 KIK51792.1 - 0.18 10.7 0.1 0.43 9.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TPR_10 PF13374.6 KIK51793.1 - 1.3e-74 244.3 4.4 5.8e-07 29.2 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK51793.1 - 9.9e-68 224.4 22.8 2.2e-11 43.9 0.1 8.8 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KIK51793.1 - 2.9e-12 45.7 15.9 1.2 9.3 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK51793.1 - 1.8e-09 37.0 14.9 0.41 10.6 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK51793.1 - 1.9e-08 34.4 0.3 0.058 13.6 0.0 5.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Rapsyn_N PF10579.9 KIK51793.1 - 2.7e-07 30.6 0.1 0.39 10.8 0.0 6.3 4 3 2 6 6 6 1 Rapsyn N-terminal myristoylation and linker region TPR_19 PF14559.6 KIK51793.1 - 3e-07 30.8 4.3 6.2 7.4 0.0 6.5 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51793.1 - 1.5e-06 27.9 9.6 1.9 8.9 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK51793.1 - 1.9e-06 27.6 23.4 1.4 9.2 0.1 9.3 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK51793.1 - 2.3e-06 28.1 4.3 5.2 7.8 0.2 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 KIK51793.1 - 8.1e-06 25.8 2.0 35 5.0 0.0 7.1 8 0 0 8 8 7 0 PPR repeat TPR_4 PF07721.14 KIK51793.1 - 4.7e-05 23.6 0.1 69 4.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK51793.1 - 0.00013 22.5 3.7 34 5.6 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF2664 PF10867.8 KIK51793.1 - 0.00032 21.1 9.8 0.052 14.0 0.3 6.5 8 1 1 9 9 7 1 Protein of unknown function (DUF2664) TPR_9 PF13371.6 KIK51793.1 - 0.00057 20.0 2.4 0.8 9.9 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 KIK51793.1 - 0.00059 19.1 0.1 0.0029 16.8 0.1 2.1 1 1 0 1 1 1 1 NB-ARC domain MCPVI PF02993.14 KIK51793.1 - 0.0012 18.8 2.7 10 5.8 0.0 5.0 1 1 3 6 6 6 0 Minor capsid protein VI DUF3856 PF12968.7 KIK51793.1 - 0.004 17.2 0.4 5.3 7.1 0.0 4.9 2 1 4 6 6 6 1 Domain of Unknown Function (DUF3856) Zincin_2 PF10103.9 KIK51793.1 - 0.0041 16.4 0.2 0.95 8.7 0.0 3.2 2 2 1 3 3 3 1 Zincin-like metallopeptidase BTAD PF03704.17 KIK51793.1 - 0.006 17.0 7.9 3.8 7.9 0.3 5.4 1 1 3 6 6 6 1 Bacterial transcriptional activator domain TPR_11 PF13414.6 KIK51793.1 - 0.014 15.0 1.7 30 4.4 0.0 5.1 5 0 0 5 5 5 0 TPR repeat TPR_3 PF07720.12 KIK51793.1 - 0.023 14.7 0.1 14 5.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK51793.1 - 0.074 12.8 0.7 10 5.8 0.0 4.4 3 2 2 5 5 5 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 KIK51793.1 - 0.15 12.8 5.7 3.6e+02 2.1 0.0 6.9 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK51793.1 - 3.3 8.3 10.4 72 4.1 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Cornichon PF03311.14 KIK51794.1 - 0.11 12.8 0.2 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 Cornichon protein KDZ PF18758.1 KIK51795.1 - 3.6e-15 56.2 0.6 3.6e-15 56.2 0.6 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FBA PF04300.13 KIK51795.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 F-box associated region TPR_5 PF12688.7 KIK51796.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Tetratrico peptide repeat Cript PF10235.9 KIK51797.1 - 0.013 16.1 2.0 0.055 14.0 2.0 2.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Sec8_exocyst PF04048.14 KIK51797.1 - 0.16 11.9 6.6 2.8 7.8 0.1 3.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain VasL PF12486.8 KIK51797.1 - 1.1 9.1 5.5 1.5 8.7 0.7 3.1 3 0 0 3 3 3 0 Type VI secretion system, EvfB, or VasL DZR PF12773.7 KIK51797.1 - 8.5 6.5 8.1 6.9 6.8 2.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF1700 PF08006.11 KIK51798.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MMR_HSR1 PF01926.23 KIK51799.1 - 1.7e-06 28.1 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK51799.1 - 0.00038 19.9 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK51799.1 - 0.00052 20.1 0.4 0.017 15.2 0.2 2.1 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 KIK51799.1 - 0.0025 17.6 0.3 0.019 14.8 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KIK51799.1 - 0.0048 16.8 0.1 0.012 15.5 0.1 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KIK51799.1 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KIK51799.1 - 0.016 15.7 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK51799.1 - 0.023 15.2 0.0 0.023 15.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIK51799.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KIK51799.1 - 0.036 13.3 0.0 0.054 12.8 0.0 1.4 1 1 0 1 1 1 0 Septin AAA_22 PF13401.6 KIK51799.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK51799.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KIK51799.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK51799.1 - 0.14 12.6 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK51799.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KIK51799.1 - 0.2 11.1 0.0 2.7 7.5 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KIK51799.1 - 0.21 11.8 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KIK51799.1 - 0.22 11.3 0.0 0.52 10.0 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Peptidase_S49_N PF08496.10 KIK51801.1 - 0.005 16.9 0.4 0.0087 16.1 0.4 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal PKcGMP_CC PF16808.5 KIK51801.1 - 0.013 15.3 2.8 0.78 9.6 0.5 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 KIK51801.1 - 0.014 14.8 2.2 0.021 14.2 2.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF3584 PF12128.8 KIK51801.1 - 0.035 11.6 4.6 0.047 11.2 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KIK51801.1 - 0.036 14.1 2.8 0.065 13.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 KIK51801.1 - 0.18 11.8 6.4 0.18 11.8 0.9 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spore_III_AB PF09548.10 KIK51801.1 - 0.22 11.6 2.1 0.34 11.0 2.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CENP-K PF11802.8 KIK51801.1 - 0.28 10.7 6.9 0.44 10.1 6.9 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF641 PF04859.12 KIK51801.1 - 0.47 10.8 5.1 4 7.8 5.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 KIK51801.1 - 0.51 10.1 6.2 2.7 7.8 0.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 KIK51801.1 - 0.57 10.3 3.6 0.47 10.6 0.3 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Csm1_N PF18504.1 KIK51801.1 - 0.64 10.4 9.2 3.1 8.2 1.0 2.6 1 1 0 2 2 2 0 Csm1 N-terminal domain Cnn_1N PF07989.11 KIK51801.1 - 1.6 8.9 5.6 4.2 7.6 0.4 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Retrotrans_gag PF03732.17 KIK51803.1 - 0.0045 17.2 0.0 0.0066 16.7 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 KIK51804.1 - 0.17 12.0 3.1 0.27 11.3 0.1 2.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain ZapB PF06005.12 KIK51804.1 - 0.19 12.2 5.3 0.54 10.7 5.2 1.9 1 1 0 1 1 1 0 Cell division protein ZapB p47_phox_C PF08944.11 KIK51806.1 - 6.7 6.2 7.5 11 5.6 4.9 2.4 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain RicinB_lectin_2 PF14200.6 KIK51807.1 - 0.00011 22.9 0.4 0.003 18.3 0.3 2.1 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 KIK51809.1 - 2.1e-05 25.2 2.0 0.0026 18.4 2.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like KDZ PF18758.1 KIK51811.1 - 6.5e-10 39.0 4.1 6.8e-10 38.9 4.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase BAR_3 PF16746.5 KIK51815.1 - 0.006 16.3 1.5 0.5 10.0 0.2 2.1 2 0 0 2 2 2 2 BAR domain of APPL family HMMR_N PF15905.5 KIK51816.1 - 0.012 15.2 6.7 0.016 14.7 6.7 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KIK51816.1 - 0.055 13.6 5.8 0.035 14.2 4.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sec2p PF06428.11 KIK51816.1 - 0.097 12.6 5.9 0.052 13.5 1.1 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4201 PF13870.6 KIK51816.1 - 0.14 11.9 4.3 0.25 11.1 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 KIK51816.1 - 0.17 10.7 8.5 0.26 10.1 8.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KIK51816.1 - 0.17 12.0 4.6 0.32 11.2 4.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIK51816.1 - 0.18 11.9 1.9 0.31 11.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KIK51816.1 - 0.35 10.1 11.0 0.064 12.5 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PKcGMP_CC PF16808.5 KIK51816.1 - 0.51 10.2 5.5 12 5.9 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LRS4 PF10422.9 KIK51816.1 - 0.8 9.2 6.8 1.3 8.6 6.8 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Csm1_N PF18504.1 KIK51816.1 - 1.1 9.7 8.7 8.5 6.8 0.6 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KIK51816.1 - 1.3 9.2 3.3 2.6 8.2 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 KIK51816.1 - 3.6 8.0 5.8 11 6.5 5.6 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FAM76 PF16046.5 KIK51816.1 - 3.9 6.8 11.5 0.057 12.8 0.8 2.1 2 0 0 2 2 2 0 FAM76 protein Tropomyosin_1 PF12718.7 KIK51816.1 - 5 7.3 11.1 26 4.9 11.1 1.9 1 1 0 1 1 1 0 Tropomyosin like ADIP PF11559.8 KIK51816.1 - 5.9 7.0 8.4 46 4.1 7.4 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding BEN PF10523.9 KIK51817.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 1 1 2 2 2 0 BEN domain FXR_C3 PF16097.5 KIK51818.1 - 0.53 11.0 4.0 1 10.1 4.0 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 Peptidase_S49_N PF08496.10 KIK51819.1 - 0.00039 20.5 0.2 0.0006 19.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK51819.1 - 0.021 13.7 6.4 0.029 13.3 6.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KIK51819.1 - 0.035 13.9 6.4 1.3 8.9 1.3 2.9 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 KIK51819.1 - 0.078 12.3 4.3 0.1 11.9 4.3 1.1 1 0 0 1 1 1 0 FAM76 protein Cnn_1N PF07989.11 KIK51819.1 - 0.081 13.1 5.0 0.097 12.8 0.3 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TolA_bind_tri PF16331.5 KIK51819.1 - 0.14 12.3 2.9 0.44 10.6 2.7 2.0 1 1 0 1 1 1 0 TolA binding protein trimerisation Phage_GP20 PF06810.11 KIK51819.1 - 0.2 11.5 6.3 2.7 7.8 0.7 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.8 KIK51819.1 - 0.2 11.7 5.8 0.45 10.6 5.3 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KIK51819.1 - 0.24 11.7 6.0 1.8 8.9 6.0 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Sec2p PF06428.11 KIK51819.1 - 0.25 11.3 8.8 0.17 11.9 2.2 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p LRS4 PF10422.9 KIK51819.1 - 0.5 9.9 8.8 0.03 13.9 3.6 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Fib_alpha PF08702.10 KIK51819.1 - 0.74 10.0 4.7 1.7 8.8 4.7 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 KIK51819.1 - 1.5 8.9 12.2 7.2 6.7 9.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KIK51819.1 - 2.6 8.4 8.5 5.2 7.5 1.1 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Med9 PF07544.13 KIK51819.1 - 3.2 7.9 6.3 6.3 7.0 0.4 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4939 PF16297.5 KIK51821.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RicinB_lectin_2 PF14200.6 KIK51822.1 - 0.0052 17.5 0.3 0.047 14.4 0.1 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Leucyl-specific PF14795.6 KIK51822.1 - 0.082 13.0 0.0 1 9.5 0.0 2.3 1 1 1 2 2 2 0 Leucine-tRNA synthetase-specific domain DEAD PF00270.29 KIK51826.1 - 8.6e-17 61.4 0.0 4e-10 39.7 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK51826.1 - 3e-08 34.0 0.1 1.5e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KIK51828.1 - 1.3e-07 31.4 0.1 2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MANEC PF07502.14 KIK51829.1 - 0.04 14.2 0.1 0.092 13.0 0.1 1.6 1 0 0 1 1 1 0 MANEC domain SRP54_N PF02881.19 KIK51830.1 - 0.027 14.7 1.4 1.2 9.4 0.1 2.3 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain Abhydrolase_6 PF12697.7 KIK51831.1 - 1.8e-10 41.8 0.1 5.6e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK51831.1 - 6.7e-05 22.7 0.0 0.00019 21.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK51831.1 - 0.00012 21.4 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIK51831.1 - 0.038 13.5 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 KIK51831.1 - 0.083 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 KIK51831.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Retrotrans_gag PF03732.17 KIK51832.1 - 3.7e-07 30.3 0.3 6.1e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Dehydratase_hem PF13816.6 KIK51832.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase RVP_2 PF08284.11 KIK51833.1 - 8.5e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIK51833.1 - 2.3e-07 31.3 0.0 3.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK51833.1 - 1e-06 29.3 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIK51833.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease zf-C3HC4 PF00097.25 KIK51839.1 - 2.4e-06 27.3 4.8 5.6e-06 26.1 4.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK51839.1 - 1.1e-05 25.3 9.0 8e-05 22.6 3.0 2.4 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK51839.1 - 1.3e-05 25.2 6.6 2.9e-05 24.1 6.6 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK51839.1 - 2.2e-05 24.2 7.2 0.00063 19.5 8.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK51839.1 - 5.1e-05 23.5 8.8 8.7e-05 22.8 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK51839.1 - 0.00014 21.6 6.2 0.00034 20.4 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK51839.1 - 0.013 15.4 9.0 0.037 13.9 9.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK51839.1 - 0.12 12.3 10.8 1.1 9.3 11.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 KIK51839.1 - 0.52 10.5 9.2 0.37 11.0 6.6 2.1 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KIK51839.1 - 1.7 9.0 10.4 5 7.5 10.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain TF_AP-2 PF03299.14 KIK51840.1 - 0.0058 16.6 7.8 0.015 15.3 7.8 1.6 1 0 0 1 1 1 1 Transcription factor AP-2 AAA_23 PF13476.6 KIK51840.1 - 0.55 10.7 7.9 1.5 9.3 7.9 1.7 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 KIK51844.1 - 2.1 8.9 4.8 5.1 7.6 0.0 3.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein PQQ PF01011.21 KIK51845.1 - 0.016 15.1 0.0 0.058 13.4 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 KIK51845.1 - 0.02 15.2 0.0 23 5.4 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK51845.1 - 0.047 14.6 9.3 0.13 13.2 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat Peptidase_C48 PF02902.19 KIK51846.1 - 0.0021 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF5605 PF18310.1 KIK51846.1 - 0.025 14.4 0.1 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) Inhibitor_I78 PF11720.8 KIK51847.1 - 0.0052 16.8 0.1 0.21 11.7 0.0 2.1 1 1 1 2 2 2 2 Peptidase inhibitor I78 family Retrotrans_gag PF03732.17 KIK51848.1 - 2.7e-07 30.8 1.4 3.3e-07 30.5 1.4 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein XH PF03469.14 KIK51848.1 - 0.026 14.5 0.6 0.034 14.1 0.6 1.1 1 0 0 1 1 1 0 XH domain DHHA1 PF02272.19 KIK51848.1 - 0.063 13.7 0.2 0.31 11.5 0.3 1.8 2 0 0 2 2 2 0 DHHA1 domain Cwf_Cwc_15 PF04889.12 KIK51850.1 - 2.9e-15 56.7 2.8 3.9e-15 56.3 2.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Helicase_C PF00271.31 KIK51851.1 - 2.3e-17 63.4 0.0 2.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIK51852.1 - 2.2e-57 194.4 0.4 3.6e-57 193.7 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KIK51852.1 - 3.1e-10 40.1 0.0 5.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK51852.1 - 9.6e-09 35.5 0.0 3.8e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KIK51852.1 - 0.0029 17.3 0.2 0.0065 16.2 0.2 1.5 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 KIK51852.1 - 0.0084 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Transposase_21 PF02992.14 KIK51855.1 - 6.6e-09 35.3 0.0 7.7e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 Cauli_VI PF01693.16 KIK51857.1 - 0.0023 18.2 0.9 0.0062 16.8 0.9 1.8 1 1 0 1 1 1 1 Caulimovirus viroplasmin Spc29 PF17082.5 KIK51857.1 - 0.0027 17.6 1.4 0.004 17.0 1.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 Herpes_UL25 PF01499.16 KIK51857.1 - 0.019 13.5 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family CdvA PF18822.1 KIK51857.1 - 0.028 14.2 0.6 0.044 13.6 0.6 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Cluap1 PF10234.9 KIK51857.1 - 0.03 13.7 1.8 0.047 13.1 1.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1542 PF07564.11 KIK51857.1 - 1.8 8.8 4.3 3.6 7.8 0.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) ResIII PF04851.15 KIK51858.1 - 0.0059 16.6 0.0 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2063 PF09836.9 KIK51858.1 - 0.032 14.5 0.0 0.063 13.5 0.0 1.4 2 0 0 2 2 2 0 Putative DNA-binding domain AAA_22 PF13401.6 KIK51858.1 - 0.091 13.0 0.0 0.099 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF1658 PF07871.11 KIK51860.1 - 1.6 8.8 3.6 0.94 9.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) NACHT PF05729.12 KIK51861.1 - 8.8e-07 29.0 0.0 2.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK51861.1 - 4.3e-05 22.8 0.1 8.6e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK51861.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK51861.1 - 0.023 14.7 0.1 0.68 10.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIK51861.1 - 0.031 13.5 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4848 PF16140.5 KIK51861.1 - 0.035 13.7 0.1 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) AAA_16 PF13191.6 KIK51861.1 - 0.038 14.4 0.0 0.073 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Hol_Tox PF16935.5 KIK51863.1 - 0.15 12.1 0.0 5.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) Nop14 PF04147.12 KIK51871.1 - 0.00029 19.2 10.8 0.00033 19.0 10.8 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KIK51871.1 - 0.00032 19.2 4.7 0.00036 19.0 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein VPS13 PF16908.5 KIK51871.1 - 0.00058 19.7 1.0 0.00086 19.2 1.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SAPS PF04499.15 KIK51871.1 - 0.048 12.4 1.7 0.057 12.2 1.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 KIK51871.1 - 0.081 12.3 19.5 0.11 11.9 19.5 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 KIK51871.1 - 0.65 9.3 19.2 0.97 8.8 19.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.6 KIK51871.1 - 0.68 8.6 4.7 0.94 8.2 4.7 1.1 1 0 0 1 1 1 0 Raftlin TRAP_alpha PF03896.16 KIK51871.1 - 4.8 6.3 10.5 7.8 5.6 10.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit COPI_C PF06957.11 KIK51871.1 - 5.2 5.7 8.4 7.4 5.2 8.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Roughex PF06020.11 KIK51871.1 - 6 5.9 9.8 8.5 5.4 9.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NmrA PF05368.13 KIK51872.1 - 1.6e-19 70.4 0.0 5.9e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK51872.1 - 0.0006 19.8 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HTH_Tnp_Mu_2 PF09039.11 KIK51874.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Kinesin PF00225.23 KIK51877.1 - 2.7e-08 33.1 0.0 3.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.23 KIK51878.1 - 7.5e-18 64.5 0.5 8.2e-18 64.4 0.5 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK51878.1 - 2.4e-11 43.8 0.2 2.5e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 Microtubule binding Microcin PF03526.13 KIK51878.1 - 0.12 12.2 1.1 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Colicin E1 (microcin) immunity protein Helicase_C PF00271.31 KIK51879.1 - 4.9e-18 65.5 0.0 5.9e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIK51880.1 - 1.2e-19 70.3 1.3 2.8e-17 62.5 0.0 3.0 1 1 2 3 3 3 3 SNF2 family N-terminal domain RRM_1 PF00076.22 KIK51883.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mor PF08765.11 KIK51884.1 - 0.039 13.9 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family ResIII PF04851.15 KIK51886.1 - 0.0092 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TAF PF02969.17 KIK51887.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Acyl_transf_1 PF00698.21 KIK51888.1 - 0.038 13.5 0.0 0.043 13.3 0.0 1.0 1 0 0 1 1 1 0 Acyl transferase domain DUF373 PF04123.13 KIK51890.1 - 0.063 12.7 0.2 0.06 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ribonuclease_3 PF00636.26 KIK51892.1 - 0.00053 20.6 0.0 0.0012 19.5 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK51892.1 - 0.0046 17.1 0.0 0.047 13.8 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease-III-like ResIII PF04851.15 KIK51892.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Abhydrolase_6 PF12697.7 KIK51893.1 - 1.2e-06 29.3 0.0 1.8e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK51893.1 - 0.013 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK51893.1 - 0.044 13.4 0.0 0.087 12.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK51893.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KIK51893.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Integrase_H2C2 PF17921.1 KIK51894.1 - 0.0042 17.2 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KIK51895.1 - 0.044 14.0 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Ank_4 PF13637.6 KIK51898.1 - 3.6e-13 49.7 0.0 6.5e-09 36.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK51898.1 - 2.7e-10 40.7 0.2 6.2e-10 39.5 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK51898.1 - 2.3e-08 34.1 0.2 0.00067 20.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KIK51898.1 - 7.4e-07 29.0 0.0 0.01 16.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KIK51898.1 - 0.0025 18.1 0.3 0.01 16.1 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 KIK51898.1 - 0.021 15.3 1.7 0.67 10.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) CMAS PF02353.20 KIK51898.1 - 0.12 11.7 0.4 0.11 11.8 0.4 1.0 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NACHT PF05729.12 KIK51899.1 - 7e-07 29.3 0.0 2.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK51899.1 - 4.4e-05 22.8 0.0 0.00011 21.5 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK51899.1 - 0.0086 16.3 0.0 0.02 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIK51899.1 - 0.017 15.2 0.0 0.33 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK51899.1 - 0.018 15.4 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 KIK51899.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KIK51899.1 - 0.11 12.8 0.1 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KIK51899.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MaoC_dehydratas PF01575.19 KIK51904.1 - 1e-10 41.2 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Acyl_transf_1 PF00698.21 KIK51905.1 - 9.7e-25 87.7 0.0 9.3e-16 58.2 0.0 3.3 1 1 1 2 2 2 2 Acyl transferase domain SLED PF12140.8 KIK51905.1 - 0.037 14.5 0.2 0.23 12.0 0.1 2.3 2 1 1 3 3 3 0 SLED domain RNA_pol_Rpb1_1 PF04997.12 KIK51906.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Plavaka PF18759.1 KIK51907.1 - 1.9e-17 63.5 0.0 2.3e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK51908.1 - 3.2e-13 49.6 0.1 3.4e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase zf-CCHC PF00098.23 KIK51909.1 - 0.0012 18.9 3.6 0.0012 18.9 3.6 1.9 2 0 0 2 2 2 1 Zinc knuckle Fib_alpha PF08702.10 KIK51911.1 - 0.031 14.5 1.8 0.063 13.5 1.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 KIK51911.1 - 0.042 14.2 1.6 0.077 13.3 1.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KIK51911.1 - 0.061 12.2 6.1 0.095 11.6 6.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KIK51911.1 - 0.077 13.3 6.5 0.43 10.9 1.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 KIK51911.1 - 6.2 6.8 5.8 0.99 9.3 0.6 2.4 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Retrotran_gag_2 PF14223.6 KIK51912.1 - 1.2e-13 50.9 0.0 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type IL4 PF00727.18 KIK51917.1 - 0.16 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Interleukin 4 Ribonuclease_3 PF00636.26 KIK51919.1 - 0.0044 17.6 0.0 0.013 16.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK51919.1 - 0.0054 16.9 0.0 0.069 13.3 0.0 2.4 1 1 0 1 1 1 1 Ribonuclease-III-like ResIII PF04851.15 KIK51919.1 - 0.0099 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5080 PF16883.5 KIK51919.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5080) Abhydrolase_6 PF12697.7 KIK51920.1 - 9.4e-11 42.7 0.1 2.3e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK51920.1 - 0.00012 21.8 0.0 0.00029 20.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK51920.1 - 0.00041 19.7 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIK51920.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KIK51920.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.13 KIK51920.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ribonuclease_3 PF00636.26 KIK51921.1 - 2.2e-33 115.0 0.0 2.6e-15 56.9 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KIK51921.1 - 7.8e-22 77.3 0.0 2e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KIK51921.1 - 8.9e-21 74.4 0.0 3.5e-07 30.4 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.29 KIK51921.1 - 3.9e-14 52.8 0.0 7.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK51921.1 - 1.3e-13 51.2 0.0 3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK51921.1 - 2.6e-13 50.4 0.0 5.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit COesterase PF00135.28 KIK51924.1 - 5e-69 233.5 0.0 2.6e-59 201.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK51924.1 - 5.6e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-CCHC PF00098.23 KIK51926.1 - 0.0084 16.1 2.3 0.0084 16.1 2.3 2.5 2 0 0 2 2 2 1 Zinc knuckle NPR1_interact PF15699.5 KIK51928.1 - 0.022 15.4 1.5 0.037 14.6 1.5 1.3 1 0 0 1 1 1 0 NPR1 interacting DUF3886 PF13025.6 KIK51928.1 - 0.03 14.5 5.8 0.03 14.5 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DDE_3 PF13358.6 KIK51929.1 - 5.2e-06 26.3 0.0 0.081 12.7 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease PIG-S PF10510.9 KIK51930.1 - 9.7e-117 390.9 7.2 2.9e-103 346.5 3.0 2.0 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein BLOC1S3 PF15753.5 KIK51930.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF5127 PF17168.4 KIK51931.1 - 1.7e-68 230.8 1.2 3e-68 230.0 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIK51931.1 - 6.1e-43 147.1 4.9 1.5e-42 145.9 4.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIK51931.1 - 7.4e-42 142.9 0.1 2.2e-41 141.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) Bac_rhamnosid6H PF17389.2 KIK51931.1 - 0.001 18.4 0.1 0.0035 16.6 0.1 1.8 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KIK51931.1 - 0.0054 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) SKG6 PF08693.10 KIK51931.1 - 0.026 13.9 0.2 0.057 12.8 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3813 PF12758.7 KIK51932.1 - 0.092 13.1 0.4 0.14 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) KDZ PF18758.1 KIK51933.1 - 2.7e-38 131.8 0.0 6.4e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK51933.1 - 1.3e-17 63.9 3.5 1.7e-17 63.6 1.4 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK51933.1 - 6.6e-05 22.7 0.8 0.00018 21.3 0.8 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK51933.1 - 0.0027 17.8 0.8 0.0087 16.2 0.4 2.1 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases C1_2 PF03107.16 KIK51933.1 - 0.004 17.4 1.6 0.015 15.6 1.6 2.0 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 KIK51933.1 - 0.015 15.1 1.4 0.042 13.7 1.4 1.7 1 0 0 1 1 1 0 HIT zinc finger CENP-F_leu_zip PF10473.9 KIK51935.1 - 0.0019 18.2 1.0 0.0034 17.4 1.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 KIK51935.1 - 0.086 12.3 0.2 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 MSP1_C PF07462.11 KIK51935.1 - 0.13 10.9 0.9 2.3 6.8 0.2 2.1 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus TMF_DNA_bd PF12329.8 KIK51935.1 - 0.21 11.6 1.4 0.47 10.5 1.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-CCHC PF00098.23 KIK51937.1 - 5.2e-05 23.1 1.9 5.9e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 Zinc knuckle Viral_NABP PF05515.11 KIK51937.1 - 0.086 12.7 0.0 4.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Viral nucleic acid binding AAA_lid_7 PF17867.1 KIK51937.1 - 0.19 12.0 0.1 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 Midasin AAA lid domain DUF5127 PF17168.4 KIK51939.1 - 4.4e-68 229.5 1.2 7.9e-68 228.6 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIK51939.1 - 6.2e-46 156.9 2.9 1.4e-45 155.8 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIK51939.1 - 2.2e-42 144.6 0.2 4.4e-42 143.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF4964 PF16334.5 KIK51939.1 - 0.00012 21.6 0.0 0.00059 19.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK51939.1 - 0.00036 19.9 1.3 0.0015 17.9 0.3 2.4 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SKG6 PF08693.10 KIK51939.1 - 0.0094 15.3 1.2 0.019 14.4 1.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SKG6 PF08693.10 KIK51940.1 - 0.00089 18.6 1.7 0.0022 17.4 1.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Cwf_Cwc_15 PF04889.12 KIK51940.1 - 0.072 12.8 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF5127 PF17168.4 KIK51941.1 - 2.4e-63 214.0 5.1 2.4e-63 214.0 5.1 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK51941.1 - 3e-45 154.0 2.1 3.1e-45 153.9 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK51941.1 - 1.4e-35 123.2 0.4 3.2e-35 122.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK51941.1 - 0.00067 19.2 0.1 0.0018 17.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK51941.1 - 0.0023 17.2 0.0 0.0067 15.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain ACP_syn_III_C PF08541.10 KIK51941.1 - 0.053 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Fungal_trans_2 PF11951.8 KIK51941.1 - 0.073 11.9 0.5 0.49 9.2 0.2 2.3 3 0 0 3 3 3 0 Fungal specific transcription factor domain DUF4984 PF16372.5 KIK51941.1 - 0.098 12.6 2.4 5 7.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4984) adh_short PF00106.25 KIK51942.1 - 9.9e-26 90.4 0.3 1.8e-25 89.6 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK51942.1 - 9.5e-16 58.1 1.2 4.5e-15 55.8 1.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK51942.1 - 3.7e-07 30.2 1.3 8.8e-07 29.0 0.4 1.8 1 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK51942.1 - 0.01 15.3 0.0 0.83 9.1 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIK51942.1 - 0.044 13.1 0.0 0.14 11.4 0.0 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PP2C PF00481.21 KIK51943.1 - 7.4e-13 48.7 0.1 5.4e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KIK51943.1 - 0.0015 18.2 0.1 0.03 14.0 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C APG9 PF04109.16 KIK51944.1 - 0.037 13.0 0.1 0.061 12.3 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg9 Phos_pyr_kin PF08543.12 KIK51945.1 - 1.4e-79 267.0 0.0 8.8e-79 264.4 0.0 2.0 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KIK51945.1 - 4.1e-25 88.8 0.2 3.7e-19 69.4 0.0 2.4 2 1 0 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 KIK51945.1 - 1.6e-05 24.3 0.0 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 KIK51945.1 - 0.0003 20.2 1.6 0.044 13.2 0.1 2.6 3 0 0 3 3 3 2 Hydroxyethylthiazole kinase family HDA2-3 PF11496.8 KIK51945.1 - 0.052 12.7 2.1 0.097 11.8 0.2 2.2 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 TENA_THI-4 PF03070.16 KIK51946.1 - 2.5e-10 40.5 0.2 3.5e-10 40.0 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF2170 PF09938.9 KIK51947.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) VIR_N PF15912.5 KIK51949.1 - 3.6 7.1 9.0 5.3 6.5 9.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1308 PF07000.11 KIK51950.1 - 0.00015 21.8 2.5 0.42 10.5 0.0 3.9 3 1 0 4 4 4 2 Protein of unknown function (DUF1308) Keratin_2_head PF16208.5 KIK51950.1 - 0.22 11.7 24.2 0.42 10.7 24.2 1.4 1 0 0 1 1 1 0 Keratin type II head Neisseria_TspB PF05616.13 KIK51950.1 - 0.41 9.1 5.3 0.68 8.3 5.3 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NADH_B2 PF14813.6 KIK51953.1 - 0.065 13.0 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Protocadherin PF08374.11 KIK51954.1 - 0.014 15.4 1.7 0.02 14.9 1.7 1.2 1 0 0 1 1 1 0 Protocadherin Mito_fiss_reg PF05308.11 KIK51955.1 - 0.23 11.5 7.4 0.26 11.3 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_S10 PF00450.22 KIK51960.1 - 8.7e-107 358.1 0.0 1.1e-106 357.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NACHT PF05729.12 KIK51961.1 - 5.3e-06 26.4 0.3 1.1e-05 25.4 0.3 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK51961.1 - 0.0036 17.7 0.1 0.0068 16.8 0.1 1.5 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KIK51961.1 - 0.02 14.1 0.2 0.25 10.5 0.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 KIK51961.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain RhoGEF PF00621.20 KIK51963.1 - 7e-26 91.6 0.0 1.4e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain FolB PF02152.18 KIK51963.1 - 0.1 13.2 1.2 0.19 12.3 0.3 1.9 2 0 0 2 2 2 0 Dihydroneopterin aldolase DSPc PF00782.20 KIK51965.1 - 1.1e-06 28.5 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK51965.1 - 0.0014 18.2 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KIK51965.1 - 0.0023 17.6 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KIK51965.1 - 0.003 17.5 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KIK51965.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Met_synt_B12 PF02965.17 KIK51965.1 - 0.23 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain ChaC PF04752.12 KIK51966.1 - 2.4e-53 180.8 0.0 2.8e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF4038 PF13204.6 KIK51966.1 - 0.027 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) zf-MYND PF01753.18 KIK51967.1 - 1.6e-08 34.5 13.3 2.8e-08 33.7 12.8 1.7 1 1 0 1 1 1 1 MYND finger Pertactin PF03212.14 KIK51968.1 - 0.051 13.5 9.7 2.5 8.0 0.3 4.9 2 1 4 6 6 6 0 Pertactin Aldo_ket_red PF00248.21 KIK51969.1 - 1e-45 156.2 0.0 1.8e-43 148.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 KIK51969.1 - 0.052 13.4 0.0 0.097 12.5 0.0 1.5 1 1 0 1 1 1 0 Development and cell death domain DUF21 PF01595.20 KIK51970.1 - 1.2e-27 96.7 0.2 1.9e-27 96.1 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIK51970.1 - 2e-06 28.1 0.2 0.066 13.7 0.0 3.4 3 0 0 3 3 3 2 CBS domain Pkinase_Tyr PF07714.17 KIK51971.1 - 3.3e-13 49.5 0.0 4.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK51971.1 - 1.8e-09 37.3 0.0 2.1e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Skp1 PF01466.19 KIK51972.1 - 7.7e-18 64.4 0.1 1.2e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK51972.1 - 2.3e-10 40.5 0.6 6.7e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain F-box-like PF12937.7 KIK51975.1 - 4.7e-09 36.0 1.1 1.3e-08 34.6 1.1 1.8 1 0 0 1 1 1 1 F-box-like FA_desaturase PF00487.24 KIK51976.1 - 1.8e-22 80.4 18.2 1.8e-22 80.4 18.2 1.6 1 1 1 2 2 2 1 Fatty acid desaturase FA_desaturase PF00487.24 KIK51978.1 - 7.6e-28 98.0 30.5 1.3e-27 97.3 30.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIK51978.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 KIK51979.1 - 6.3e-26 91.7 21.1 9.7e-26 91.1 21.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIK51979.1 - 0.0055 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TSC22 PF01166.18 KIK51982.1 - 0.00035 20.8 1.0 0.00079 19.7 0.9 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family EzrA PF06160.12 KIK51982.1 - 0.0008 17.7 2.7 0.00091 17.5 2.7 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SHE3 PF17078.5 KIK51982.1 - 0.0011 18.7 5.5 0.0021 17.8 5.5 1.4 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF812 PF05667.11 KIK51982.1 - 0.0018 17.3 2.5 0.0021 17.1 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Leu_zip PF15294.6 KIK51982.1 - 0.0019 17.8 3.4 0.0022 17.6 3.4 1.0 1 0 0 1 1 1 1 Leucine zipper DivIC PF04977.15 KIK51982.1 - 0.0021 17.8 2.0 0.005 16.6 2.0 1.7 1 1 0 1 1 1 1 Septum formation initiator YscO PF07321.12 KIK51982.1 - 0.0026 17.7 2.3 0.0033 17.4 1.6 1.4 1 1 0 1 1 1 1 Type III secretion protein YscO APG6_N PF17675.1 KIK51982.1 - 0.003 18.1 4.8 0.0037 17.8 4.2 1.5 1 1 0 1 1 1 1 Apg6 coiled-coil region DUF4201 PF13870.6 KIK51982.1 - 0.0035 17.1 1.3 0.0048 16.7 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) FadA PF09403.10 KIK51982.1 - 0.004 17.6 1.6 0.0067 16.9 1.6 1.4 1 0 0 1 1 1 1 Adhesion protein FadA Filament PF00038.21 KIK51982.1 - 0.0042 16.7 2.1 0.0044 16.7 2.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Lectin_N PF03954.14 KIK51982.1 - 0.0063 16.3 0.7 0.01 15.6 0.6 1.4 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain YabA PF06156.13 KIK51982.1 - 0.0069 17.0 2.5 0.0094 16.6 2.4 1.3 1 1 0 1 1 1 1 Initiation control protein YabA GAS PF13851.6 KIK51982.1 - 0.0073 15.7 4.8 0.016 14.6 4.3 1.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KIK51982.1 - 0.0079 16.4 5.6 0.012 15.8 5.6 1.5 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 RasGAP_C PF03836.15 KIK51982.1 - 0.0079 16.3 2.1 0.009 16.2 2.1 1.1 1 0 0 1 1 1 1 RasGAP C-terminus DMPK_coil PF08826.10 KIK51982.1 - 0.011 15.9 1.8 0.026 14.6 0.3 2.3 3 0 0 3 3 2 0 DMPK coiled coil domain like V_ATPase_I PF01496.19 KIK51982.1 - 0.012 13.6 3.4 0.012 13.5 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 KIK51982.1 - 0.013 15.9 3.7 0.071 13.5 1.3 2.0 1 1 1 2 2 2 0 Snapin/Pallidin FapA PF03961.13 KIK51982.1 - 0.014 14.0 1.9 0.015 13.9 1.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3584 PF12128.8 KIK51982.1 - 0.014 13.0 3.9 0.016 12.8 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 KIK51982.1 - 0.015 15.7 4.6 0.028 14.8 4.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Wtap PF17098.5 KIK51982.1 - 0.019 14.9 4.3 0.03 14.2 0.7 2.1 1 1 1 2 2 2 0 WTAP/Mum2p family CdvA PF18822.1 KIK51982.1 - 0.019 14.8 4.0 0.057 13.3 4.0 1.6 1 1 0 1 1 1 0 CdvA-like coiled-coil domain KASH_CCD PF14662.6 KIK51982.1 - 0.02 14.7 4.7 0.022 14.6 4.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KIK51982.1 - 0.021 14.9 1.4 0.021 14.9 1.4 2.3 1 1 2 3 3 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 KIK51982.1 - 0.022 14.8 7.0 0.059 13.4 7.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 KIK51982.1 - 0.024 15.3 3.1 0.034 14.9 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Spc7 PF08317.11 KIK51982.1 - 0.027 13.3 3.7 0.03 13.2 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KIK51982.1 - 0.029 14.8 5.9 0.034 14.6 5.9 1.1 1 0 0 1 1 1 0 Fez1 Tropomyosin PF00261.20 KIK51982.1 - 0.033 13.5 4.9 0.021 14.2 3.5 1.4 1 1 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.7 KIK51982.1 - 0.036 14.2 5.6 0.047 13.8 4.9 1.6 1 1 1 2 2 2 0 Tropomyosin like ATG16 PF08614.11 KIK51982.1 - 0.039 14.2 8.1 0.029 14.6 6.4 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KIK51982.1 - 0.04 14.0 3.7 0.13 12.3 3.7 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GCN5L1 PF06320.13 KIK51982.1 - 0.043 14.0 0.3 0.069 13.3 0.3 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Fib_alpha PF08702.10 KIK51982.1 - 0.044 14.0 4.0 0.048 13.8 4.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 KIK51982.1 - 0.044 14.4 2.2 0.11 13.1 2.2 1.9 1 1 0 1 1 1 0 SlyX ADIP PF11559.8 KIK51982.1 - 0.046 13.8 6.2 0.039 14.0 5.1 1.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Nnf1 PF03980.14 KIK51982.1 - 0.048 14.0 3.2 0.053 13.9 0.6 2.1 2 1 0 2 2 2 0 Nnf1 TMF_TATA_bd PF12325.8 KIK51982.1 - 0.05 13.8 4.8 0.1 12.8 4.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 KIK51982.1 - 0.058 12.6 2.0 0.065 12.5 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein CENP-H PF05837.12 KIK51982.1 - 0.058 13.8 4.7 0.097 13.1 4.6 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) SOGA PF11365.8 KIK51982.1 - 0.06 14.5 3.9 0.13 13.4 3.9 1.7 1 1 0 1 1 1 0 Protein SOGA ABC_tran_CTD PF16326.5 KIK51982.1 - 0.061 13.6 2.2 0.076 13.3 1.0 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF3768 PF12599.8 KIK51982.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) CCDC-167 PF15188.6 KIK51982.1 - 0.066 13.6 4.6 0.22 11.9 4.4 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ax_dynein_light PF10211.9 KIK51982.1 - 0.069 13.1 4.3 0.07 13.1 3.7 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain TMF_DNA_bd PF12329.8 KIK51982.1 - 0.075 13.0 8.2 0.055 13.5 3.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 KIK51982.1 - 0.077 13.4 5.0 0.17 12.3 4.6 1.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Shugoshin_N PF07558.11 KIK51982.1 - 0.078 12.9 1.7 0.1 12.5 0.3 2.0 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region OmpH PF03938.14 KIK51982.1 - 0.079 13.3 1.7 0.12 12.7 1.5 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DHR10 PF18595.1 KIK51982.1 - 0.097 12.7 5.7 0.058 13.4 3.1 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 KIK51982.1 - 0.098 13.1 2.1 0.2 12.1 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Swi5 PF07061.11 KIK51982.1 - 0.098 12.7 2.6 0.42 10.7 2.6 2.0 1 1 0 1 1 1 0 Swi5 Prefoldin PF02996.17 KIK51982.1 - 0.11 12.5 2.3 0.17 11.8 1.0 1.9 1 1 1 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 KIK51982.1 - 0.11 12.8 3.3 3.3 8.0 0.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KIK51982.1 - 0.11 11.6 5.3 0.12 11.4 5.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_2 PF07716.15 KIK51982.1 - 0.11 12.6 1.6 0.11 12.6 1.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Fmp27_WPPW PF10359.9 KIK51982.1 - 0.14 11.0 4.9 0.14 11.0 4.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4140 PF13600.6 KIK51982.1 - 0.18 12.3 2.6 0.46 11.0 2.0 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 KIK51982.1 - 0.2 11.9 5.4 0.91 9.8 5.4 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3552 PF12072.8 KIK51982.1 - 0.31 10.4 5.2 0.43 10.0 5.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) XhlA PF10779.9 KIK51982.1 - 1.2 9.3 3.3 1.3 9.3 0.8 2.0 1 1 0 2 2 2 0 Haemolysin XhlA Choline_kinase PF01633.20 KIK51986.1 - 0.0054 16.3 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIK51986.1 - 0.026 14.4 0.0 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KIK51986.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KIK51986.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NB-ARC PF00931.22 KIK51989.1 - 2.5e-05 23.6 0.4 0.00045 19.5 0.4 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK51989.1 - 3.6e-05 24.2 0.0 8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK51989.1 - 0.0042 17.0 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea CbiA PF01656.23 KIK51989.1 - 0.0097 16.0 0.1 0.012 15.7 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KIK51989.1 - 0.019 15.3 0.2 0.047 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIK51989.1 - 0.025 14.2 0.4 0.057 13.0 0.2 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2204 PF09970.9 KIK51989.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) ResIII PF04851.15 KIK51989.1 - 0.049 13.6 0.3 0.064 13.2 0.3 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KIK51989.1 - 0.083 12.9 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK51989.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 KIK51989.1 - 0.15 11.5 0.0 0.57 9.6 0.0 1.8 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA PF00004.29 KIK51989.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.6 KIK51990.1 - 4.6e-135 436.4 22.9 3.1e-10 39.6 0.1 14.0 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_12 PF13424.6 KIK51990.1 - 1.6e-92 303.9 23.6 1.6e-12 47.5 0.5 12.8 4 3 9 13 13 13 13 Tetratricopeptide repeat TPR_7 PF13176.6 KIK51990.1 - 1.1e-24 84.6 26.4 0.06 13.4 0.0 13.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK51990.1 - 4.4e-23 80.1 50.3 0.015 15.1 0.6 13.6 14 0 0 14 14 14 8 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK51990.1 - 4.5e-16 58.7 11.5 3.9 7.6 0.0 12.6 7 4 7 14 14 13 1 Rapsyn N-terminal myristoylation and linker region TPR_2 PF07719.17 KIK51990.1 - 5.5e-16 57.3 43.7 0.3 11.3 0.2 13.6 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK51990.1 - 6.7e-16 58.6 23.8 0.26 11.8 0.2 11.7 1 1 11 13 13 13 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK51990.1 - 3.9e-15 54.7 38.3 0.48 10.8 0.1 13.4 14 0 0 14 14 13 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK51990.1 - 6.3e-15 55.0 20.0 1.2 9.3 0.0 13.0 14 0 0 14 14 14 3 Fis1 C-terminal tetratricopeptide repeat YqaH PF17448.2 KIK51990.1 - 7.4e-12 45.4 0.7 9 6.7 0.0 9.7 2 1 10 12 12 12 0 Uncharacterized YqaH-like TPR_4 PF07721.14 KIK51990.1 - 2e-10 40.3 0.0 17 6.4 0.0 9.1 10 0 0 10 10 9 0 Tetratricopeptide repeat Paf67 PF10255.9 KIK51990.1 - 7.2e-10 38.4 0.6 1.1 8.2 0.0 5.9 1 1 5 7 7 7 2 RNA polymerase I-associated factor PAF67 ANAPC3 PF12895.7 KIK51990.1 - 7.8e-10 38.8 10.3 0.22 11.8 0.0 9.0 2 2 6 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KIK51990.1 - 7.9e-09 35.7 14.5 11 6.4 0.0 11.7 2 2 10 13 13 13 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK51990.1 - 2.7e-08 33.7 8.4 1.3 8.7 0.2 7.2 5 4 0 6 6 6 1 26S proteasome subunit RPN7 PPR PF01535.20 KIK51990.1 - 4.7e-08 32.8 11.4 14 6.2 0.0 10.7 12 0 0 12 12 11 0 PPR repeat DUF3400 PF11880.8 KIK51990.1 - 8.1e-06 25.3 0.5 21 4.7 0.0 7.3 9 0 0 9 9 7 0 Domain of unknown function (DUF3400) Titin_Ig-rpts PF06582.12 KIK51990.1 - 2.2e-05 24.3 22.0 6.8 6.7 0.1 10.5 11 0 0 11 11 10 0 Titin repeat TPR_9 PF13371.6 KIK51990.1 - 3.9e-05 23.7 2.0 18 5.6 0.0 7.9 8 3 3 11 11 11 0 Tetratricopeptide repeat DUF4866 PF16160.5 KIK51990.1 - 0.00085 18.7 14.1 0.88 8.8 0.1 6.2 1 1 6 8 8 8 1 Domain of unknown function (DUF4866) RIG-I_C PF18119.1 KIK51990.1 - 0.006 16.6 16.2 7.5 6.6 0.1 7.9 3 2 5 9 9 9 0 RIG-I receptor C-terminal domain TIG_2 PF18020.1 KIK51990.1 - 0.0065 17.1 0.4 77 4.0 0.0 6.4 2 2 6 9 9 8 0 TIG domain found in plexin DUF3660 PF12398.8 KIK51990.1 - 0.0077 16.3 0.2 20 5.3 0.0 5.5 9 0 0 9 9 4 0 Receptor serine/threonine kinase Phage_GPA PF05840.13 KIK51990.1 - 0.0086 15.2 4.4 9.2 5.2 0.0 4.8 1 1 1 5 5 5 0 Bacteriophage replication gene A protein (GPA) DUF4913 PF16259.5 KIK51990.1 - 0.057 13.5 0.6 99 3.1 0.0 5.6 8 1 1 9 9 4 0 Domain of unknown function (DUF4913) GTF2I PF02946.14 KIK51990.1 - 0.097 12.7 0.3 3.1e+02 1.5 0.0 5.9 6 3 3 9 9 7 0 GTF2I-like repeat DUF5341 PF17276.2 KIK51990.1 - 0.16 12.1 2.0 19 5.4 0.0 3.9 3 1 1 4 4 4 0 Family of unknown function (DUF5341) TPR_17 PF13431.6 KIK51990.1 - 0.3 11.6 56.3 0.76 10.3 0.7 12.0 14 0 0 14 14 13 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK51990.1 - 0.58 10.9 28.9 25 5.8 0.0 11.0 12 2 0 12 12 9 0 Tetratricopeptide repeat BTAD PF03704.17 KIK51990.1 - 0.7 10.3 13.8 1 9.8 0.4 5.8 3 3 1 6 6 6 0 Bacterial transcriptional activator domain TPR_16 PF13432.6 KIK51990.1 - 1.3 9.8 14.3 1e+02 3.7 0.0 7.6 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK51990.1 - 3.4 7.4 25.9 81 3.0 0.1 10.3 12 0 0 12 12 11 0 TPR repeat ACP_PD PF04336.12 KIK51990.1 - 4.7 7.7 16.6 2 8.9 0.5 6.3 1 1 6 8 8 8 0 Acyl carrier protein phosphodiesterase DUF713 PF05218.14 KIK51991.1 - 0.047 13.4 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Sec10 PF07393.11 KIK51995.1 - 1.7e-10 40.0 0.0 2.2e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KIK51995.1 - 0.38 10.7 3.2 0.41 10.6 0.1 2.4 3 0 0 3 3 3 0 F-box-like Pkinase PF00069.25 KIK51996.1 - 0.0064 15.9 0.0 0.0087 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK51996.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK51996.1 - 0.058 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mo-nitro_C PF06967.11 KIK51997.1 - 0.05 13.6 0.1 0.095 12.7 0.1 1.5 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus MMS1_N PF10433.9 KIK52001.1 - 4.3e-09 35.5 0.0 4.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA_16 PF13191.6 KIK52007.1 - 0.0001 22.7 0.0 0.00014 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK52007.1 - 0.0014 17.9 0.3 0.023 13.9 0.3 2.0 1 1 0 1 1 1 1 NB-ARC domain CbiA PF01656.23 KIK52007.1 - 0.0032 17.5 0.0 0.0059 16.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 KIK52007.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2204 PF09970.9 KIK52007.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) ResIII PF04851.15 KIK52007.1 - 0.029 14.4 0.2 0.043 13.8 0.2 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KIK52007.1 - 0.036 13.7 0.2 0.062 12.9 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIK52007.1 - 0.046 14.0 0.1 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIK52007.1 - 0.088 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 KIK52007.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_11 PF13086.6 KIK52007.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain TPR_10 PF13374.6 KIK52008.1 - 1.1e-115 374.9 24.6 2.2e-10 40.0 0.1 14.0 14 1 0 14 14 14 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK52008.1 - 5.6e-83 273.3 21.3 1.1e-12 48.0 0.4 12.7 5 3 8 13 13 13 13 Tetratricopeptide repeat TPR_7 PF13176.6 KIK52008.1 - 6.2e-25 85.4 21.7 0.15 12.1 0.1 13.2 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK52008.1 - 1.8e-21 75.0 43.5 0.014 15.2 0.6 12.4 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 KIK52008.1 - 5.5e-15 55.6 23.9 0.2 12.2 0.3 10.9 2 2 10 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK52008.1 - 5.8e-15 54.1 38.7 0.27 11.5 0.2 12.5 13 0 0 13 13 13 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK52008.1 - 1.4e-14 53.8 13.9 1.1 9.3 0.0 11.6 12 0 0 12 12 12 2 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.9 KIK52008.1 - 3.8e-13 49.3 6.1 4.9 7.3 0.0 11.1 5 4 6 12 12 12 1 Rapsyn N-terminal myristoylation and linker region TPR_8 PF13181.6 KIK52008.1 - 6.4e-13 47.8 31.5 0.94 9.9 0.2 12.1 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK52008.1 - 1.4e-10 40.7 0.0 8.2 7.4 0.0 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK52008.1 - 2.6e-09 37.3 12.1 11 6.5 0.0 11.0 4 3 7 12 12 12 0 Tetratricopeptide repeat YqaH PF17448.2 KIK52008.1 - 3.4e-09 36.9 0.1 68 3.9 0.0 8.6 3 2 7 10 10 10 0 Uncharacterized YqaH-like ANAPC3 PF12895.7 KIK52008.1 - 9.9e-09 35.3 9.0 0.24 11.6 0.0 8.0 1 1 9 10 10 10 1 Anaphase-promoting complex, cyclosome, subunit 3 Paf67 PF10255.9 KIK52008.1 - 2.1e-08 33.6 0.0 1.2 8.0 0.0 5.4 1 1 5 6 6 6 2 RNA polymerase I-associated factor PAF67 RPN7 PF10602.9 KIK52008.1 - 7.2e-08 32.3 4.7 4.8 6.8 0.1 6.8 5 4 1 6 6 6 1 26S proteasome subunit RPN7 PPR PF01535.20 KIK52008.1 - 8.5e-08 31.9 7.8 13 6.3 0.0 9.4 11 0 0 11 11 9 0 PPR repeat Titin_Ig-rpts PF06582.12 KIK52008.1 - 1.7e-07 31.1 11.6 6.5 6.8 0.1 10.0 12 0 0 12 12 11 0 Titin repeat DUF3400 PF11880.8 KIK52008.1 - 3.6e-07 29.6 0.1 15 5.3 0.0 7.0 8 0 0 8 8 7 0 Domain of unknown function (DUF3400) TPR_9 PF13371.6 KIK52008.1 - 1.1e-05 25.5 2.2 13 6.0 0.0 7.6 7 3 2 10 10 10 0 Tetratricopeptide repeat RIG-I_C PF18119.1 KIK52008.1 - 0.00095 19.2 11.6 11 6.0 0.1 6.8 3 2 4 8 8 8 0 RIG-I receptor C-terminal domain Phage_GPA PF05840.13 KIK52008.1 - 0.0014 17.8 3.5 1.2 8.2 0.1 4.6 1 1 5 7 7 7 1 Bacteriophage replication gene A protein (GPA) DUF4866 PF16160.5 KIK52008.1 - 0.0032 16.8 10.7 1.3 8.3 0.1 5.7 1 1 5 7 7 7 1 Domain of unknown function (DUF4866) TPR_17 PF13431.6 KIK52008.1 - 0.0056 17.0 47.7 0.72 10.4 0.7 11.3 13 0 0 13 13 12 1 Tetratricopeptide repeat DUF4913 PF16259.5 KIK52008.1 - 0.035 14.2 0.4 1.2e+02 2.8 0.0 5.7 9 0 0 9 9 7 0 Domain of unknown function (DUF4913) TIG_2 PF18020.1 KIK52008.1 - 0.047 14.3 0.2 73 4.1 0.0 5.2 3 3 4 8 8 7 0 TIG domain found in plexin TPR_16 PF13432.6 KIK52008.1 - 0.27 11.9 12.0 81 4.0 0.0 7.6 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK52008.1 - 0.42 11.4 24.4 24 5.8 0.0 10.0 10 1 0 10 10 10 0 Tetratricopeptide repeat BTAD PF03704.17 KIK52008.1 - 0.85 10.0 10.3 1.8 9.0 0.4 5.0 3 2 2 5 5 5 0 Bacterial transcriptional activator domain ACP_PD PF04336.12 KIK52008.1 - 1 9.8 12.8 4.3 7.8 0.2 5.6 3 2 4 7 7 7 0 Acyl carrier protein phosphodiesterase AAA_16 PF13191.6 KIK52010.1 - 0.00014 22.3 0.0 0.00018 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK52010.1 - 0.0013 18.0 0.1 0.02 14.1 0.1 2.0 1 1 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KIK52010.1 - 0.012 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ResIII PF04851.15 KIK52010.1 - 0.031 14.3 0.2 0.038 14.0 0.2 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK52010.1 - 0.031 14.6 0.2 0.076 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIK52010.1 - 0.033 13.8 0.2 0.062 12.9 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KIK52010.1 - 0.036 14.1 0.1 0.042 13.9 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2204 PF09970.9 KIK52010.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) TrwB_AAD_bind PF10412.9 KIK52010.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 KIK52010.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RecA PF00154.21 KIK52010.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TPR_10 PF13374.6 KIK52011.1 - 4e-51 169.6 6.4 2.5e-10 39.9 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK52011.1 - 4.5e-37 126.2 4.9 8.8e-11 41.9 0.2 5.9 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KIK52011.1 - 9.1e-12 44.1 8.7 0.11 12.6 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK52011.1 - 4.4e-09 35.8 14.7 0.01 15.6 0.2 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK52011.1 - 2.5e-08 33.4 15.2 0.18 12.0 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK52011.1 - 4.5e-08 33.1 0.1 7.6 6.7 0.0 5.1 3 2 2 5 5 5 0 Rapsyn N-terminal myristoylation and linker region TPR_19 PF14559.6 KIK52011.1 - 2.9e-07 30.9 1.6 3 8.4 0.0 4.9 2 1 3 5 5 5 2 Tetratricopeptide repeat Paf67 PF10255.9 KIK52011.1 - 5.8e-07 28.9 0.1 0.002 17.2 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I-associated factor PAF67 TPR_8 PF13181.6 KIK52011.1 - 3.6e-06 26.7 10.3 0.5 10.7 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK52011.1 - 1.6e-05 24.9 1.8 11 6.2 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 KIK52011.1 - 0.00018 21.5 1.5 15 6.1 0.0 5.3 6 0 0 6 6 5 0 PPR repeat TPR_4 PF07721.14 KIK52011.1 - 0.00027 21.3 0.0 38 5.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4866 PF16160.5 KIK52011.1 - 0.00028 20.3 1.0 0.57 9.5 0.1 2.8 1 1 1 3 3 3 2 Domain of unknown function (DUF4866) TPR_20 PF14561.6 KIK52011.1 - 0.00045 20.5 2.3 3.2 8.2 0.0 5.4 1 1 3 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KIK52011.1 - 0.00068 19.7 0.2 1.2 9.2 0.0 3.5 1 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KIK52011.1 - 0.0012 19.0 1.3 0.99 9.7 0.1 4.1 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2977 PF11192.8 KIK52011.1 - 0.0018 18.3 0.0 12 6.1 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2977) RPN7 PF10602.9 KIK52011.1 - 0.0027 17.4 0.9 6.9 6.3 0.1 4.0 3 2 1 4 4 4 0 26S proteasome subunit RPN7 Phage_GPA PF05840.13 KIK52011.1 - 0.0029 16.8 0.1 0.31 10.1 0.1 2.2 1 1 1 2 2 2 2 Bacteriophage replication gene A protein (GPA) YqaH PF17448.2 KIK52011.1 - 0.0037 17.5 0.1 25 5.3 0.0 4.0 1 1 4 5 5 5 0 Uncharacterized YqaH-like TPR_MalT PF17874.1 KIK52011.1 - 0.0065 15.9 1.9 2.9 7.2 0.1 2.7 1 1 1 3 3 3 2 MalT-like TPR region TPR_11 PF13414.6 KIK52011.1 - 0.012 15.3 4.0 41 4.0 0.0 5.0 5 1 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 KIK52011.1 - 0.015 15.6 14.3 0.24 11.9 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK52011.1 - 0.06 14.0 2.4 48 4.7 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 KIK52011.1 - 0.11 12.6 0.6 22 5.2 0.0 3.5 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KIK52011.1 - 0.17 12.6 4.0 29 5.6 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat RIG-I_C PF18119.1 KIK52011.1 - 0.17 11.9 2.2 18 5.4 0.0 3.7 1 1 3 4 4 4 0 RIG-I receptor C-terminal domain DUF4529 PF15032.6 KIK52017.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) BTB PF00651.31 KIK52017.1 - 0.1 12.8 0.6 0.33 11.2 0.5 1.9 1 1 0 1 1 1 0 BTB/POZ domain DDT PF02791.17 KIK52019.1 - 0.0081 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 DDT domain Sigma70_r2 PF04542.14 KIK52020.1 - 0.054 13.3 0.3 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 Sigma-70 region 2 KOW PF00467.29 KIK52021.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 0 KOW motif FUSC-like PF12805.7 KIK52025.1 - 0.0071 15.5 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS Asp_protease_2 PF13650.6 KIK52025.1 - 0.048 14.3 0.0 0.096 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KIK52025.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SR-25 PF10500.9 KIK52026.1 - 4.4 6.8 7.5 0.34 10.5 0.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DIM PF08194.12 KIK52028.1 - 0.099 12.9 0.3 0.13 12.4 0.3 1.2 1 0 0 1 1 1 0 DIM protein Tam41_Mmp37 PF09139.11 KIK52030.1 - 1.1e-98 330.6 0.0 1.5e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DER1 PF04511.15 KIK52031.1 - 1.1e-46 159.2 1.9 1.3e-46 158.9 1.9 1.0 1 0 0 1 1 1 1 Der1-like family TLD PF07534.16 KIK52032.1 - 1.3e-28 100.0 0.0 2.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 TLD NDK PF00334.19 KIK52033.1 - 1.9e-16 60.3 0.0 3.6e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase T2SSB PF16537.5 KIK52035.1 - 0.054 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system protein B PhoLip_ATPase_C PF16212.5 KIK52036.1 - 0.0021 17.8 2.6 0.0021 17.8 2.6 1.7 1 1 1 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Ferric_reduct PF01794.19 KIK52036.1 - 1.6 8.9 9.7 0.34 11.1 5.0 2.4 2 1 0 2 2 2 0 Ferric reductase like transmembrane component Alg6_Alg8 PF03155.15 KIK52038.1 - 2.9e-134 448.7 12.9 3.9e-134 448.3 12.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF4436 PF14494.6 KIK52039.1 - 0.0081 15.5 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) zf-MYND PF01753.18 KIK52040.1 - 3.9e-09 36.5 10.4 3.9e-09 36.5 10.4 2.0 2 0 0 2 2 2 1 MYND finger SET PF00856.28 KIK52040.1 - 1.4e-08 35.3 0.0 2.2e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 SET domain 2-oxogl_dehyd_N PF16078.5 KIK52040.1 - 0.02 14.5 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus LSM PF01423.22 KIK52041.1 - 8e-19 67.1 0.2 9e-19 66.9 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK52041.1 - 2.5e-05 24.3 0.1 3.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KIK52041.1 - 0.04 14.0 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain AMP-binding PF00501.28 KIK52042.1 - 8.3e-77 258.6 0.0 1.3e-76 257.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK52042.1 - 0.0022 18.9 0.0 0.0079 17.1 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cytochrom_B561 PF03188.16 KIK52042.1 - 0.043 14.0 1.3 0.11 12.7 1.3 1.7 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Cation_ATPase_C PF00689.21 KIK52042.1 - 1.6 8.4 4.8 0.31 10.7 0.2 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus PhoLip_ATPase_C PF16212.5 KIK52042.1 - 2 8.1 7.4 0.1 12.3 1.3 1.8 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal ATG16 PF08614.11 KIK52043.1 - 2.5e-06 27.9 64.9 0.0008 19.7 6.8 5.4 1 1 4 5 5 5 4 Autophagy protein 16 (ATG16) MAD PF05557.13 KIK52043.1 - 6.6e-05 21.5 69.5 0.0064 14.9 28.1 3.0 1 1 2 3 3 3 2 Mitotic checkpoint protein EzrA PF06160.12 KIK52043.1 - 0.00037 18.8 56.0 0.0028 15.9 14.5 4.3 1 1 3 4 4 4 2 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 KIK52043.1 - 0.00053 20.2 42.8 0.35 11.2 4.3 6.1 2 2 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 KIK52043.1 - 0.00067 19.9 64.0 0.015 15.5 4.6 8.1 3 2 7 10 10 10 4 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 KIK52043.1 - 0.002 18.2 18.7 0.002 18.2 18.7 6.2 1 1 4 5 5 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KIK52043.1 - 0.0031 16.2 52.8 0.0077 14.9 21.1 2.7 1 1 2 3 3 3 3 AAA domain APG6_N PF17675.1 KIK52043.1 - 0.0048 17.4 10.4 0.0048 17.4 10.4 6.2 1 1 4 5 5 4 1 Apg6 coiled-coil region Filament PF00038.21 KIK52043.1 - 0.0074 15.9 62.2 0.011 15.3 38.3 3.1 1 1 2 3 3 3 1 Intermediate filament protein HMMR_N PF15905.5 KIK52043.1 - 0.0084 15.6 61.8 0.23 10.9 19.6 3.2 1 1 2 3 3 3 3 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 KIK52043.1 - 0.018 12.6 64.2 0.2 9.2 11.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Cnn_1N PF07989.11 KIK52043.1 - 0.018 15.2 3.5 0.018 15.2 3.5 6.7 2 2 3 6 6 6 0 Centrosomin N-terminal motif 1 APC_N_CC PF16689.5 KIK52043.1 - 0.019 15.0 0.1 0.019 15.0 0.1 6.0 6 3 2 8 8 6 0 Coiled-coil N-terminus of APC, dimerisation domain DUF948 PF06103.11 KIK52043.1 - 0.023 14.9 22.5 0.54 10.6 0.7 6.2 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KIK52043.1 - 0.024 13.5 67.8 0.51 9.2 18.0 4.8 1 1 5 6 6 6 0 Spc7 kinetochore protein Lebercilin PF15619.6 KIK52043.1 - 0.025 14.2 65.8 0.12 12.0 17.6 4.3 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin_2 PF14523.6 KIK52043.1 - 0.026 14.9 3.0 0.026 14.9 3.0 5.3 1 1 3 4 4 3 0 Syntaxin-like protein DUF4407 PF14362.6 KIK52043.1 - 0.033 13.5 52.3 0.045 13.1 15.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 KIK52043.1 - 0.035 13.7 57.9 0.15 11.6 35.9 4.4 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Val_tRNA-synt_C PF10458.9 KIK52043.1 - 0.065 13.5 0.4 0.065 13.5 0.4 7.9 7 1 3 10 10 8 0 Valyl tRNA synthetase tRNA binding arm SlyX PF04102.12 KIK52043.1 - 0.13 12.8 0.3 0.13 12.8 0.3 7.5 3 2 5 8 8 8 0 SlyX Seryl_tRNA_N PF02403.22 KIK52043.1 - 0.17 12.1 66.5 1.8 8.8 1.6 6.8 1 1 6 7 7 7 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KIK52043.1 - 0.24 11.8 41.8 4.2 7.8 0.2 7.8 4 2 4 9 9 7 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KIK52043.1 - 0.32 10.3 61.7 0.54 9.5 9.8 5.6 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KIK52043.1 - 0.35 11.0 64.1 0.047 13.8 12.2 6.9 1 1 2 5 5 4 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KIK52043.1 - 0.5 10.5 44.0 0.57 10.4 11.7 5.0 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 KIK52043.1 - 0.65 9.0 61.0 0.39 9.8 12.2 4.0 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KIK52043.1 - 0.78 10.2 61.6 4.6 7.6 20.8 4.2 1 1 2 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.12 KIK52043.1 - 0.81 9.8 67.1 0.81 9.7 18.1 5.6 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KIK52043.1 - 1.4 9.5 48.1 0.099 13.1 9.6 5.8 2 1 2 4 4 4 0 Protein of unknown function DUF16 SCO1-SenC PF02630.14 KIK52043.1 - 1.6 8.6 3.9 2.2 8.2 0.3 2.9 2 1 1 3 3 3 0 SCO1/SenC TMPIT PF07851.13 KIK52043.1 - 1.7 7.8 49.5 0.29 10.3 4.4 4.7 1 1 3 5 5 5 0 TMPIT-like protein OmpH PF03938.14 KIK52043.1 - 2.3 8.6 63.3 0.11 12.8 2.4 5.8 1 1 3 5 5 5 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KIK52043.1 - 3.6 7.6 42.2 4.2 7.4 2.0 6.0 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) GAS PF13851.6 KIK52043.1 - 4.7 6.5 63.6 0.15 11.4 11.3 5.3 1 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.12 KIK52043.1 - 7.4 6.9 32.9 0.066 13.5 0.9 6.9 3 2 4 7 7 7 0 Proteins of 100 residues with WXG DUF812 PF05667.11 KIK52043.1 - 8.4 5.1 62.6 0.48 9.3 3.0 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF812) DUF2730 PF10805.8 KIK52043.1 - 9.1 6.4 33.3 2.1 8.5 1.3 6.6 2 1 5 7 7 7 0 Protein of unknown function (DUF2730) AAA_23 PF13476.6 KIK52044.1 - 3.7e-34 119.0 0.0 3.7e-34 119.0 0.0 2.8 1 1 1 2 2 1 1 AAA domain AAA_15 PF13175.6 KIK52044.1 - 1.3e-10 41.6 17.1 5.4e-09 36.2 17.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIK52044.1 - 6.2e-10 38.9 0.1 6.2e-10 38.9 0.1 3.5 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK52044.1 - 1.9e-05 24.6 4.3 4.9e-05 23.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK52044.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK52044.1 - 0.0018 18.8 11.6 1.4 9.4 11.4 3.3 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK52044.1 - 0.003 17.8 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Mod_r PF07200.13 KIK52044.1 - 0.015 15.4 5.2 0.015 15.4 5.2 3.8 1 1 3 4 4 3 0 Modifier of rudimentary (Mod(r)) protein cobW PF02492.19 KIK52044.1 - 0.028 14.0 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIK52044.1 - 0.033 13.9 0.5 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK52044.1 - 0.041 14.2 0.2 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK52044.1 - 0.056 13.8 0.0 0.056 13.8 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 KIK52044.1 - 0.086 12.4 0.0 0.086 12.4 0.0 3.2 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KIK52044.1 - 0.45 10.7 0.0 0.45 10.7 0.0 3.0 4 0 0 4 4 4 0 AAA domain DUF438 PF04282.13 KIK52044.1 - 0.47 10.5 3.5 1.5 8.9 1.4 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF438) AAA_19 PF13245.6 KIK52044.1 - 0.56 10.5 2.6 2.5 8.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KIK52044.1 - 0.84 9.2 0.0 0.84 9.2 0.0 4.1 3 1 1 4 4 4 0 AAA domain DUF5315 PF17242.2 KIK52044.1 - 9.8 6.1 14.2 0.77 9.6 1.9 3.1 3 1 1 4 4 4 0 Disordered region of unknown function (DUF5315) DUF455 PF04305.14 KIK52045.1 - 2.9e-94 315.2 0.0 3.8e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KIK52045.1 - 8.1e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KIK52045.1 - 0.00072 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyrophosphatase PF00719.19 KIK52045.1 - 0.078 12.8 0.3 17 5.2 0.0 2.5 2 1 1 3 3 3 0 Inorganic pyrophosphatase F-box-like PF12937.7 KIK52046.1 - 0.00012 21.9 0.1 0.00029 20.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like Carla_C4 PF01623.17 KIK52046.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein MRP-L47 PF06984.13 KIK52047.1 - 8.5e-21 73.9 0.5 8.5e-21 73.9 0.5 2.0 2 1 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF648 PF04890.13 KIK52047.1 - 0.1 12.3 0.4 0.13 12.0 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) ERM PF00769.19 KIK52047.1 - 1.2 8.8 18.8 1.7 8.4 18.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L29 PF00831.23 KIK52047.1 - 2.2 8.3 12.2 0.15 12.1 4.2 2.9 2 1 0 2 2 2 0 Ribosomal L29 protein MRP-S26 PF14943.6 KIK52047.1 - 2.3 8.1 11.9 3.5 7.5 11.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Complex1_LYR PF05347.15 KIK52048.1 - 6.3e-12 45.4 0.1 1e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIK52048.1 - 0.0014 19.3 0.4 0.002 18.8 0.4 1.4 1 1 0 1 1 1 1 Complex1_LYR-like MFS_1 PF07690.16 KIK52049.1 - 2.5e-28 99.0 34.0 4.1e-28 98.3 33.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 4HBT PF03061.22 KIK52051.1 - 2.2e-11 44.0 0.2 3.6e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RibD_C PF01872.17 KIK52052.1 - 1e-30 107.1 0.0 1.2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain NIF3 PF01784.18 KIK52053.1 - 1.5e-68 231.1 0.0 1.8e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ETF PF01012.21 KIK52053.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein domain zf-primase PF09329.11 KIK52056.1 - 1.5e-15 56.7 2.4 2.8e-15 55.9 2.4 1.5 1 0 0 1 1 1 1 Primase zinc finger DUF2742 PF10888.8 KIK52057.1 - 0.02 15.1 0.0 0.095 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) DUF4937 PF16291.5 KIK52058.1 - 0.12 12.6 0.0 2 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 Rhamnogal_lyase PF06045.11 KIK52060.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family AidB_N PF18158.1 KIK52061.1 - 2.7e-26 92.4 0.0 5e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIK52061.1 - 1.9e-21 76.9 0.2 7.4e-20 71.7 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK52061.1 - 5.4e-17 61.8 0.0 1.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK52061.1 - 3e-09 37.3 0.0 1.1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain He_PIG PF05345.12 KIK52061.1 - 0.035 14.3 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 Putative Ig domain Nas2_N PF18265.1 KIK52062.1 - 1.8e-27 95.1 0.1 2.3e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KIK52062.1 - 1.3e-06 28.1 0.3 0.0001 22.1 0.1 2.5 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 KIK52062.1 - 1.9e-05 25.0 0.0 0.00011 22.5 0.0 2.3 2 1 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KIK52062.1 - 7.2e-05 23.0 0.0 0.00034 20.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KIK52062.1 - 0.0061 16.9 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Thi4 PF01946.17 KIK52064.1 - 3.8e-103 343.8 0.2 4.8e-103 343.5 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK52064.1 - 2.1e-09 37.4 0.9 2.7e-08 33.8 0.4 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK52064.1 - 3.4e-07 30.4 0.0 8.8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK52064.1 - 1.8e-06 27.2 0.5 0.00016 20.8 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK52064.1 - 2.4e-05 24.4 2.4 0.00016 21.7 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIK52064.1 - 5.8e-05 22.5 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK52064.1 - 0.00018 20.8 1.0 0.0012 18.0 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK52064.1 - 0.0007 18.4 0.1 0.0012 17.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KIK52064.1 - 0.0013 18.2 0.2 0.0019 17.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIK52064.1 - 0.027 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIK52064.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK52064.1 - 0.091 11.8 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KIK52064.1 - 0.11 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KIK52064.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) CM_2 PF01817.21 KIK52067.1 - 1.7e-06 28.3 0.0 0.00038 20.8 0.0 2.5 2 0 0 2 2 2 2 Chorismate mutase type II Septin PF00735.18 KIK52068.1 - 2.3e-47 161.6 0.1 6e-17 61.8 0.0 3.7 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.23 KIK52068.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK52068.1 - 0.00034 20.2 0.0 0.0021 17.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIK52068.1 - 0.0094 16.3 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK52068.1 - 0.016 15.5 0.0 0.047 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIK52068.1 - 0.059 13.6 0.2 0.19 11.9 0.2 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK52068.1 - 0.11 12.9 0.1 0.26 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Pox_A32 PF04665.12 KIK52068.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 KIK52069.1 - 3.3e-27 95.5 0.0 3.7e-10 39.6 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 KIK52069.1 - 3.4e-19 68.7 28.3 1.3e-09 38.0 8.4 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIK52070.1 - 9.7e-08 32.0 10.3 1.5e-07 31.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 KIK52071.1 - 2.8e-205 682.9 0.8 3.2e-205 682.7 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family RIO1 PF01163.22 KIK52072.1 - 2e-71 239.5 0.0 2e-71 239.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KIK52072.1 - 0.00022 20.7 0.1 0.00072 19.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KIK52072.1 - 0.00058 19.3 1.5 0.019 14.3 1.3 2.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK52072.1 - 0.00058 19.9 0.4 0.27 11.1 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK52072.1 - 0.063 12.0 0.1 0.063 12.0 0.1 2.3 3 0 0 3 3 3 0 Fungal protein kinase Pro_isomerase PF00160.21 KIK52073.1 - 4.8e-48 163.4 0.7 8e-48 162.7 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KIK52073.1 - 5.7e-11 42.8 1.8 9.5e-05 23.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52073.1 - 0.012 15.9 0.0 1.3 9.4 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4504 PF14953.6 KIK52074.1 - 0.022 14.2 0.0 0.044 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4504) PAP2_3 PF14378.6 KIK52075.1 - 0.059 13.0 7.9 0.33 10.6 0.1 3.1 2 1 2 4 4 4 0 PAP2 superfamily DUF5602 PF18197.1 KIK52075.1 - 0.081 13.4 0.7 0.22 12.0 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5602) MpPF26 PF07666.11 KIK52075.1 - 1 9.5 12.9 0.66 10.1 0.9 3.4 3 1 0 3 3 3 0 M penetrans paralogue family 26 7tm_1 PF00001.21 KIK52075.1 - 3.8 6.8 11.3 3.2 7.0 3.1 2.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) PRA1 PF03208.19 KIK52076.1 - 0.0037 16.9 6.7 0.17 11.5 6.7 2.0 1 1 0 1 1 1 1 PRA1 family protein TMEM208_SND2 PF05620.11 KIK52076.1 - 0.35 10.6 2.8 0.67 9.7 0.7 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 HXXEE PF13787.6 KIK52076.1 - 3.3 8.6 7.0 7.8 7.4 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif F-box-like PF12937.7 KIK52077.1 - 0.00065 19.5 0.1 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK52077.1 - 0.035 14.0 0.7 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KIK52077.1 - 0.055 13.4 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 F-box Glyco_hydro_7 PF00840.20 KIK52078.1 - 6.6e-201 667.7 16.1 7.9e-201 667.4 16.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KIK52078.1 - 3.2e-11 43.0 11.5 3.2e-11 43.0 11.5 4.6 3 1 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_7 PF00840.20 KIK52079.1 - 3.5e-202 671.9 19.2 4.4e-202 671.6 19.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KIK52079.1 - 4.8e-12 45.6 11.1 4.8e-12 45.6 11.1 4.8 4 1 0 4 4 4 1 Fungal cellulose binding domain DNApol_Exo PF18136.1 KIK52080.1 - 4.6e-100 334.4 0.0 8e-100 333.6 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KIK52080.1 - 4.9e-51 174.0 0.0 8.1e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Glutaredoxin2_C PF04399.13 KIK52080.1 - 0.16 11.8 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ABC_tran_CTD PF16326.5 KIK52080.1 - 0.79 10.0 2.7 2.9 8.2 2.2 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-AN1 PF01428.16 KIK52081.1 - 2.8e-20 72.2 35.4 1e-11 44.7 8.8 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KIK52081.1 - 0.019 15.3 21.8 0.22 11.9 8.3 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain PAP2 PF01569.21 KIK52081.1 - 0.18 11.5 1.2 0.32 10.8 1.0 1.5 1 1 0 1 1 1 0 PAP2 superfamily Tir_receptor_C PF07489.11 KIK52081.1 - 4.1 7.3 11.8 5.8 6.8 11.8 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Eaf7 PF07904.13 KIK52083.1 - 5.6e-16 58.8 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 PASTA PF03793.19 KIK52085.1 - 0.0089 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 PASTA domain Big_7 PF17957.1 KIK52085.1 - 0.034 14.9 5.1 0.16 12.8 2.4 2.7 2 1 0 2 2 2 0 Bacterial Ig domain Glyco_transf_25 PF01755.17 KIK52086.1 - 1e-06 28.7 0.0 7.7e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Ufd2P_core PF10408.9 KIK52087.1 - 1.5e-221 737.4 0.1 1.8e-221 737.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KIK52087.1 - 2.9e-29 101.0 1.6 1.6e-28 98.7 1.2 2.6 2 0 0 2 2 2 1 U-box domain Sec2p PF06428.11 KIK52087.1 - 0.038 13.9 2.8 2.3 8.2 0.0 3.4 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p Mt_ATP-synt_B PF05405.14 KIK52087.1 - 0.099 12.3 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L35p PF01632.19 KIK52088.1 - 1.5e-18 67.0 7.9 1.7e-18 66.9 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 His_Phos_1 PF00300.22 KIK52089.1 - 9.4e-35 120.1 0.0 1.3e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 KIK52090.1 - 0.00012 21.9 0.9 0.00014 21.7 0.9 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK52090.1 - 0.0043 16.9 1.2 0.0058 16.5 1.2 1.3 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KIK52090.1 - 0.068 12.8 0.5 0.091 12.3 0.5 1.3 1 0 0 1 1 1 0 F-box Ada3 PF10198.9 KIK52091.1 - 8.1e-20 71.3 0.1 8.1e-20 71.3 0.1 3.4 4 1 1 5 5 5 1 Histone acetyltransferases subunit 3 Herpes_UL25 PF01499.16 KIK52091.1 - 3 6.2 5.5 0.66 8.4 0.7 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family GTP1_OBG PF01018.22 KIK52092.1 - 1.8e-42 144.6 1.2 6.5e-30 103.8 0.6 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KIK52092.1 - 2.6e-18 66.2 0.0 7e-18 64.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK52092.1 - 0.00036 20.1 0.4 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 KIK52092.1 - 0.0005 19.7 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KIK52092.1 - 0.0012 18.4 0.4 1.5 8.2 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK52092.1 - 0.0063 16.1 0.7 0.38 10.2 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK52092.1 - 0.0072 16.4 0.0 0.041 14.0 0.0 2.3 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KIK52092.1 - 0.0078 16.7 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KIK52092.1 - 0.048 14.2 0.0 0.17 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KIK52092.1 - 0.24 10.3 2.2 0.51 9.3 0.2 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KIK52094.1 - 2.1e-97 324.7 0.0 4e-97 323.7 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK52094.1 - 6.6e-37 126.2 0.2 1.1e-36 125.4 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK52094.1 - 5.5e-30 103.6 1.9 1.1e-29 102.6 1.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK52094.1 - 6e-19 68.6 0.1 2.6e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KIK52094.1 - 1.2e-08 35.1 0.0 3.4e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIK52094.1 - 1.6e-07 30.9 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK52094.1 - 5.3e-05 23.1 0.0 0.0031 17.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK52094.1 - 0.00082 19.1 0.1 0.88 9.3 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 KIK52094.1 - 0.0032 17.9 0.2 0.047 14.1 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK52094.1 - 0.076 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.6 KIK52094.1 - 0.2 10.4 0.3 0.42 9.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain HECT PF00632.25 KIK52095.1 - 1.5e-96 323.6 0.0 1.9e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIK52095.1 - 5.7e-36 122.3 13.9 9.9e-12 44.7 0.4 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIK52095.1 - 1.2e-18 67.2 0.0 3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain RasGEF_N PF00618.20 KIK52096.1 - 4e-14 52.7 0.1 1.6e-13 50.8 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 KIK52096.1 - 2.7e-09 37.5 8.1 3.5e-07 30.6 6.3 3.0 2 1 0 2 2 2 1 RasGEF domain PhoU_div PF01865.16 KIK52096.1 - 0.0025 17.2 2.8 0.25 10.6 1.9 2.6 3 0 0 3 3 3 2 Protein of unknown function DUF47 Ins_allergen_rp PF06757.13 KIK52096.1 - 0.0082 16.1 0.6 0.1 12.6 0.1 2.7 3 0 0 3 3 3 1 Insect allergen related repeat, nitrile-specifier detoxification MCU PF04678.13 KIK52096.1 - 0.026 14.6 1.7 2.7 8.1 0.1 3.3 2 1 0 2 2 2 0 Mitochondrial calcium uniporter IL11 PF07400.11 KIK52096.1 - 0.65 9.6 4.4 1.1 8.8 0.5 3.0 3 0 0 3 3 3 0 Interleukin 11 Syntaxin_2 PF14523.6 KIK52096.1 - 0.98 9.8 9.3 6.1 7.3 1.2 3.4 3 1 0 3 3 3 0 Syntaxin-like protein Muted PF14942.6 KIK52096.1 - 1.3 9.4 6.2 1 9.7 1.4 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Ribosomal_L22 PF00237.19 KIK52097.1 - 2.7e-36 123.9 0.1 3.6e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RE_Eco29kI PF09517.10 KIK52097.1 - 0.016 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease GH131_N PF18271.1 KIK52098.1 - 2.8e-51 174.7 0.7 4.1e-51 174.1 0.7 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KIK52098.1 - 8e-11 41.7 10.3 8e-11 41.7 10.3 2.3 2 1 0 2 2 2 1 Fungal cellulose binding domain RSN1_7TM PF02714.15 KIK52099.1 - 2.6e-42 145.0 17.9 6.3e-42 143.8 17.9 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIK52099.1 - 2.5e-21 76.7 0.1 1.8e-14 54.4 0.0 3.7 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK52099.1 - 3.5e-17 62.6 0.8 3.5e-17 62.6 0.8 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport ETC_C1_NDUFA4 PF04800.12 KIK52100.1 - 2.1e-36 124.0 0.1 2.7e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region CPBP PF02517.16 KIK52101.1 - 4e-14 52.7 2.9 4e-14 52.7 2.9 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2207 PF09972.9 KIK52101.1 - 0.14 10.9 0.2 0.43 9.3 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Oxidored_FMN PF00724.20 KIK52102.1 - 2.8e-69 234.0 0.0 3.5e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIK52102.1 - 0.0075 15.4 0.0 0.014 14.5 0.0 1.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NEMP PF10225.9 KIK52103.1 - 0.06 13.0 0.4 0.072 12.8 0.4 1.0 1 0 0 1 1 1 0 NEMP family DUF2781 PF10914.8 KIK52103.1 - 0.096 13.1 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Cauli_VI PF01693.16 KIK52104.1 - 0.0047 17.2 0.0 0.0071 16.6 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin PrpF PF04303.13 KIK52105.1 - 1.3e-82 277.7 0.0 1.5e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 PrpF protein TMEM239 PF15841.5 KIK52108.1 - 0.084 12.8 3.8 0.12 12.2 3.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 239 family MULE PF10551.9 KIK52109.1 - 1.1e-11 44.9 0.1 2.1e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain Pkinase PF00069.25 KIK52112.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK52112.1 - 0.0068 16.4 0.0 0.022 14.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK52112.1 - 0.0077 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK52112.1 - 0.009 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family ABC_membrane PF00664.23 KIK52113.1 - 2.8e-26 92.8 1.6 4.8e-26 92.0 1.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIK52113.1 - 4.4e-24 85.5 0.1 4.1e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK52113.1 - 0.00038 20.0 2.8 0.3 10.5 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KIK52113.1 - 0.001 19.2 0.4 0.0022 18.2 0.1 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 KIK52113.1 - 0.0035 17.2 0.1 1.1 9.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK52113.1 - 0.011 15.4 0.4 0.035 13.8 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK52113.1 - 0.013 15.9 0.3 0.03 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KIK52113.1 - 0.025 14.7 0.4 0.068 13.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase SLATT_1 PF18181.1 KIK52113.1 - 0.047 13.6 1.6 0.35 10.8 0.2 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 NB-ARC PF00931.22 KIK52113.1 - 0.13 11.4 0.1 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Aldo_ket_red PF00248.21 KIK52115.1 - 4.6e-68 229.6 0.0 6e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S15 PF02129.18 KIK52116.1 - 5.9e-10 39.2 0.1 1.3e-09 38.1 0.1 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIK52116.1 - 2e-07 30.5 0.0 3.4e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK52116.1 - 7.3e-07 29.1 0.1 5.6e-05 22.9 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK52116.1 - 3.7e-06 27.7 0.2 5.2e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK52116.1 - 7.2e-06 25.7 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 KIK52116.1 - 0.00098 18.8 0.2 0.0037 17.0 0.2 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KIK52116.1 - 0.012 15.1 0.0 0.066 12.7 0.1 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 KIK52116.1 - 0.03 14.2 0.0 0.91 9.4 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal F-box-like PF12937.7 KIK52120.1 - 0.012 15.5 0.3 0.028 14.3 0.3 1.6 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KIK52120.1 - 0.019 15.4 5.9 1.8 9.1 0.6 3.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Recep_L_domain PF01030.24 KIK52120.1 - 0.092 12.9 0.1 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 Receptor L domain DUF3990 PF13151.6 KIK52121.1 - 2.6e-05 23.9 0.1 9.1e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3990) SOG2 PF10428.9 KIK52121.1 - 3.3 6.8 18.2 4.4 6.4 18.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KIK52121.1 - 3.4 6.3 11.4 4.3 5.9 11.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Urm1 PF09138.11 KIK52122.1 - 3e-34 117.2 0.1 2.5e-33 114.3 0.1 1.9 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KIK52122.1 - 0.00039 21.0 0.0 0.00048 20.7 0.0 1.2 1 0 0 1 1 1 1 ThiS family Fungal_trans PF04082.18 KIK52123.1 - 4.3e-33 114.5 0.0 8.8e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK52123.1 - 2.4e-07 30.8 13.6 3.8e-07 30.1 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KIK52125.1 - 4.3e-71 239.4 0.0 6e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK52125.1 - 3.9e-29 101.7 0.0 6e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK52125.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK52125.1 - 0.00041 19.8 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK52125.1 - 0.0018 17.1 1.7 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIK52125.1 - 0.0031 17.5 0.0 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family CMS1 PF14617.6 KIK52125.1 - 0.45 9.8 5.5 0.75 9.1 5.5 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF4551 PF15087.6 KIK52125.1 - 0.79 8.5 6.5 0.95 8.2 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyoxal_oxid_N PF07250.11 KIK52126.1 - 9e-29 100.4 0.0 5.5e-28 97.8 0.0 2.3 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK52126.1 - 6e-22 77.8 0.2 1.8e-21 76.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KIK52126.1 - 0.00041 20.5 0.4 2.3 8.7 0.0 5.2 5 1 1 6 6 6 1 Kelch motif Kelch_4 PF13418.6 KIK52126.1 - 0.023 14.7 2.2 6.5 6.8 0.0 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 KIK52127.1 - 1.5e-29 102.9 0.0 6.7e-29 100.8 0.0 2.1 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK52127.1 - 1.2e-19 70.4 0.1 2.7e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KIK52127.1 - 0.055 13.8 0.0 1.5 9.3 0.0 3.5 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 KIK52127.1 - 0.37 10.9 2.6 14 5.7 0.1 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 KIK52128.1 - 2.6e-28 98.8 0.0 1.1e-27 96.7 0.0 2.1 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK52128.1 - 2.9e-20 72.4 0.1 6.4e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KIK52128.1 - 0.066 13.5 0.0 1.5 9.2 0.0 3.4 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 KIK52128.1 - 0.28 11.2 2.7 9.7 6.3 0.1 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain VIT1 PF01988.19 KIK52129.1 - 3.3e-64 216.7 6.4 3.9e-64 216.5 6.4 1.1 1 0 0 1 1 1 1 VIT family DUF443 PF04276.12 KIK52129.1 - 0.28 11.0 0.2 0.43 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) MFS_1 PF07690.16 KIK52130.1 - 2.5e-14 53.0 27.7 2.5e-14 53.0 27.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK52130.1 - 1e-08 35.0 4.0 1e-08 35.0 4.0 2.6 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KIK52131.1 - 4e-14 52.3 24.5 4e-14 52.3 24.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK52131.1 - 6.8e-12 45.4 3.8 6.8e-12 45.4 3.8 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Serpentine_r_xa PF03383.15 KIK52132.1 - 0.042 13.8 0.2 0.084 12.9 0.2 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa MFS_1 PF07690.16 KIK52133.1 - 7e-15 54.8 25.4 7e-15 54.8 25.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK52133.1 - 4.6e-11 42.7 4.6 4.6e-11 42.7 4.6 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Pkinase PF00069.25 KIK52134.1 - 2.1e-17 63.4 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK52134.1 - 1.7e-08 34.1 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK52134.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 KIK52136.1 - 4.2e-10 39.1 27.5 4.2e-10 39.1 27.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK52136.1 - 9.3e-09 35.2 4.8 9.3e-09 35.2 4.8 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Tyrosinase PF00264.20 KIK52138.1 - 1.9e-45 155.9 1.2 4.8e-45 154.6 1.2 1.7 1 0 0 1 1 1 1 Common central domain of tyrosinase adh_short_C2 PF13561.6 KIK52141.1 - 4.5e-06 26.4 0.0 7.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK52141.1 - 2.8e-05 23.7 0.0 5.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK52141.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 KR domain ADH_N PF08240.12 KIK52145.1 - 2.7e-27 94.8 4.3 6.6e-27 93.6 4.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK52145.1 - 1.7e-19 70.1 0.0 2.6e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK52145.1 - 2.2e-06 28.7 0.0 4.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK52145.1 - 4.7e-06 26.2 0.4 1.7e-05 24.4 0.4 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus F-box-like PF12937.7 KIK52146.1 - 0.00024 20.9 0.2 0.00024 20.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK52146.1 - 0.012 15.5 0.4 0.012 15.5 0.4 2.3 2 0 0 2 2 2 0 F-box domain Sybindin PF04099.12 KIK52147.1 - 0.091 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family CNH PF00780.22 KIK52149.1 - 5.2e-45 154.2 0.0 2.5e-43 148.7 0.0 2.2 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIK52149.1 - 3.4e-23 82.2 0.1 7e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KIK52149.1 - 1.8e-06 27.9 0.3 6.3e-06 26.1 0.1 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain CxC4 PF18717.1 KIK52150.1 - 2.1e-43 147.3 0.0 2.1e-43 147.3 0.0 1.3 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases Zn-ribbon_8 PF09723.10 KIK52150.1 - 0.016 15.3 2.7 1 9.6 0.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Glyco_hydro_43 PF04616.14 KIK52155.1 - 3.1e-19 69.4 0.0 4.8e-19 68.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 FtsJ PF01728.19 KIK52158.1 - 2.6e-42 144.9 0.0 3.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Luciferase_3H PF10284.9 KIK52158.1 - 0.2 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Luciferase helical bundle domain DIOX_N PF14226.6 KIK52160.1 - 4.9e-28 98.2 0.0 7.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK52160.1 - 2.8e-18 66.3 0.0 3e-17 63.0 0.0 2.1 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.6 KIK52161.1 - 2e-13 50.5 0.0 3.9e-13 49.6 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK52161.1 - 6.3e-10 39.6 0.0 1e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK52161.1 - 2.7e-06 27.3 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK52161.1 - 6.1e-06 25.7 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK52161.1 - 4.6e-05 24.0 0.0 7.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIK52161.1 - 0.023 14.5 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_12 PF08242.12 KIK52161.1 - 0.068 13.9 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK52162.1 - 8.5e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK52162.1 - 5.6e-07 30.2 0.0 9.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK52162.1 - 8e-05 22.1 0.0 0.00038 19.9 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK52162.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HLH PF00010.26 KIK52164.1 - 3.4e-10 39.7 0.2 6.5e-10 38.8 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_UL56 PF04534.12 KIK52164.1 - 0.003 17.1 3.7 0.003 17.1 3.7 1.7 1 1 0 1 1 1 1 Herpesvirus UL56 protein SUIM_assoc PF16619.5 KIK52164.1 - 0.0066 16.5 1.3 0.0066 16.5 1.3 1.9 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 KIK52164.1 - 0.24 11.4 4.7 0.65 9.9 1.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 KIK52164.1 - 6.7 5.8 24.8 0.13 11.4 12.8 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 KIK52164.1 - 9.8 5.7 10.2 0.31 10.6 2.9 1.9 2 0 0 2 2 2 0 Spt20 family FliD_N PF02465.18 KIK52168.1 - 0.69 10.6 0.0 0.69 10.6 0.0 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DTHCT PF08070.11 KIK52169.1 - 0.089 13.5 0.2 0.13 13.0 0.2 1.2 1 0 0 1 1 1 0 DTHCT (NUC029) region Holin_SPP1 PF04688.13 KIK52171.1 - 0.094 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 SPP1 phage holin SAP PF02037.27 KIK52172.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain Bacillus_HBL PF05791.11 KIK52173.1 - 0.0085 15.9 0.9 0.018 14.9 0.9 1.4 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) MCM6_C PF18263.1 KIK52173.1 - 0.065 13.5 0.6 0.14 12.4 0.6 1.6 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Retrotrans_gag PF03732.17 KIK52173.1 - 0.34 11.2 2.4 1 9.7 0.9 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein DUF4549 PF15082.6 KIK52173.1 - 0.47 10.2 2.9 3.4 7.4 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) Retrotran_gag_2 PF14223.6 KIK52176.1 - 4.5e-10 39.3 0.1 4.9e-10 39.2 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 KIK52176.1 - 0.0024 18.1 0.0 0.0029 17.8 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein AdoHcyase PF05221.17 KIK52176.1 - 0.038 13.1 0.1 0.042 13.0 0.1 1.0 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase 40S_SA_C PF16122.5 KIK52176.1 - 0.076 14.4 1.3 0.1 13.9 1.3 1.2 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Retrotrans_gag PF03732.17 KIK52181.1 - 5.5e-07 29.8 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK52181.1 - 0.00017 21.5 3.8 0.00033 20.6 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 KIK52181.1 - 0.036 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF745 PF05335.13 KIK52182.1 - 0.0061 16.3 8.8 0.033 13.9 4.4 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF745) DUF1635 PF07795.11 KIK52182.1 - 0.0094 15.8 4.6 0.062 13.2 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) PilO PF04350.13 KIK52182.1 - 0.013 15.6 1.7 1.4 9.1 0.4 2.8 3 1 0 3 3 2 0 Pilus assembly protein, PilO BAR_3 PF16746.5 KIK52182.1 - 0.017 14.8 8.6 0.095 12.4 5.2 2.2 2 0 0 2 2 2 0 BAR domain of APPL family PKcGMP_CC PF16808.5 KIK52182.1 - 0.056 13.3 14.3 1.4 8.9 0.2 4.7 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK52182.1 - 0.087 13.2 11.5 0.9 9.9 2.8 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Cauli_AT PF03233.13 KIK52182.1 - 0.19 11.6 2.6 3.3 7.6 0.2 2.3 2 0 0 2 2 2 0 Aphid transmission protein Fib_alpha PF08702.10 KIK52182.1 - 0.3 11.3 1.8 1.3 9.2 0.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 KIK52182.1 - 1.3 8.5 9.5 0.14 11.6 5.4 1.4 2 0 0 2 2 2 0 Leucine zipper DUF4201 PF13870.6 KIK52182.1 - 1.5 8.5 10.9 0.23 11.2 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 KIK52182.1 - 1.5 9.1 14.2 1.1 9.6 0.6 3.4 2 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.6 KIK52182.1 - 1.6 8.4 13.8 1.4 8.5 2.9 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FAM76 PF16046.5 KIK52182.1 - 2.7 7.3 5.0 4.5 6.6 5.0 1.3 1 1 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 KIK52183.1 - 0.0011 19.5 7.0 0.0018 18.8 7.0 1.2 1 0 0 1 1 1 1 Fez1 Phage_GP20 PF06810.11 KIK52183.1 - 0.0042 16.9 6.6 0.35 10.7 1.1 2.3 1 1 1 2 2 2 2 Phage minor structural protein GP20 Peptidase_S49_N PF08496.10 KIK52183.1 - 0.0053 16.8 0.2 0.0053 16.8 0.2 1.6 2 0 0 2 2 1 1 Peptidase family S49 N-terminal KASH_CCD PF14662.6 KIK52183.1 - 0.006 16.4 10.0 0.012 15.4 10.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Mei5 PF10376.9 KIK52183.1 - 0.0071 16.2 3.1 0.012 15.5 3.1 1.3 1 0 0 1 1 1 1 Double-strand recombination repair protein Spc7 PF08317.11 KIK52183.1 - 0.013 14.4 9.4 0.02 13.8 9.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 KIK52183.1 - 0.027 14.0 7.3 0.045 13.2 7.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Sec2p PF06428.11 KIK52183.1 - 0.035 14.1 1.1 0.035 14.1 1.1 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Transcrip_act PF04949.13 KIK52183.1 - 0.064 13.1 4.8 0.15 12.0 4.8 1.5 1 0 0 1 1 1 0 Transcriptional activator GAS PF13851.6 KIK52183.1 - 0.066 12.6 6.6 0.32 10.3 1.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 KIK52183.1 - 0.077 13.3 12.0 0.12 12.7 3.9 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain LRS4 PF10422.9 KIK52183.1 - 0.12 12.0 6.3 0.2 11.2 6.3 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 PKcGMP_CC PF16808.5 KIK52183.1 - 0.13 12.1 10.5 1.2 9.0 1.6 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KIK52183.1 - 0.14 11.5 2.0 0.2 11.0 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc42p PF11544.8 KIK52183.1 - 0.22 11.5 3.7 2.8 8.0 0.1 2.9 1 1 0 3 3 3 0 Spindle pole body component Spc42p ATG16 PF08614.11 KIK52183.1 - 0.24 11.6 12.5 0.69 10.1 4.3 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIK52183.1 - 0.27 11.8 10.2 0.6 10.6 10.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 KIK52183.1 - 0.36 11.5 3.1 11 6.7 0.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DUF641 PF04859.12 KIK52183.1 - 0.5 10.7 6.5 0.37 11.1 3.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.6 KIK52183.1 - 0.72 9.6 8.4 2.9 7.6 8.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FAM76 PF16046.5 KIK52183.1 - 0.96 8.7 16.0 0.026 13.9 5.6 2.6 2 1 1 3 3 3 0 FAM76 protein TMF_DNA_bd PF12329.8 KIK52183.1 - 1.8 8.6 16.3 1.2 9.2 7.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KIK52183.1 - 2.1 8.4 9.7 0.72 9.9 4.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rho_Binding PF08912.11 KIK52183.1 - 2.6 8.9 8.8 3.1 8.7 2.5 2.4 2 0 0 2 2 2 0 Rho Binding HSCB_C PF07743.13 KIK52183.1 - 4 8.0 7.4 3.1 8.3 4.9 2.1 2 0 0 2 2 1 0 HSCB C-terminal oligomerisation domain CC2-LZ PF16516.5 KIK52183.1 - 7.3 7.0 9.5 18 5.8 4.0 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RhoGEF PF00621.20 KIK52184.1 - 1.9e-07 31.5 0.0 2.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain CUT PF02376.15 KIK52188.1 - 0.2 11.9 0.2 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 CUT domain Myf5 PF12232.8 KIK52189.1 - 2.6 8.9 7.7 3 8.7 0.5 2.5 2 0 0 2 2 2 0 Myogenic determination factor 5 F-box-like PF12937.7 KIK52190.1 - 0.049 13.5 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 F-box-like DUF5323 PF17257.2 KIK52193.1 - 0.11 12.4 0.2 0.37 10.7 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Myf5 PF12232.8 KIK52196.1 - 0.97 10.3 7.0 2.8 8.8 0.5 2.4 2 0 0 2 2 2 0 Myogenic determination factor 5 CNH PF00780.22 KIK52197.1 - 4.7e-60 203.5 0.0 7e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KIK52197.1 - 7.3e-33 114.3 0.5 1.3e-29 103.7 0.0 3.3 3 0 0 3 3 3 2 RhoGEF domain PH_5 PF15405.6 KIK52197.1 - 5.6e-13 49.2 0.0 8.8e-12 45.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 KIK52197.1 - 0.0087 16.1 0.0 0.045 13.8 0.0 2.1 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KIK52197.1 - 0.12 12.9 0.0 18 5.9 0.0 2.5 2 0 0 2 2 2 0 PH domain p450 PF00067.22 KIK52200.1 - 2.2e-47 161.9 0.0 3.9e-33 114.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Anthrax_toxA PF03497.16 KIK52201.1 - 0.011 15.9 2.6 0.011 15.9 2.6 2.6 3 0 0 3 3 3 0 Anthrax toxin LF subunit Spc7 PF08317.11 KIK52201.1 - 0.013 14.4 51.4 0.096 11.6 11.0 3.5 1 1 0 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 KIK52201.1 - 0.18 12.2 50.5 0.099 13.1 19.2 3.9 1 1 3 4 4 4 0 Fez1 DUF745 PF05335.13 KIK52201.1 - 0.42 10.3 39.7 2.1 8.0 0.5 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 KIK52201.1 - 0.84 9.8 55.6 0.15 12.3 5.9 4.9 2 2 2 4 4 4 0 Tropomyosin like DUF1759 PF03564.15 KIK52201.1 - 1.5 8.7 10.5 0.34 10.9 2.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) HALZ PF02183.18 KIK52201.1 - 1.7 9.0 11.9 1.1 9.6 0.5 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF1490 PF07371.12 KIK52201.1 - 3.6 7.7 6.3 0.35 11.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) ATG16 PF08614.11 KIK52201.1 - 4 7.6 63.2 0.73 10.0 17.4 3.9 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KIK52201.1 - 8.1 7.1 36.5 0.97 10.1 1.9 6.0 3 2 3 6 6 6 0 SlyX Spc7 PF08317.11 KIK52202.1 - 0.00024 20.1 12.4 0.00024 20.1 12.4 3.5 1 1 1 3 3 3 1 Spc7 kinetochore protein ATG16 PF08614.11 KIK52202.1 - 0.0017 18.7 53.5 0.21 11.8 6.4 4.6 1 1 2 4 4 4 4 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KIK52202.1 - 0.0038 17.1 7.4 0.0038 17.1 7.4 3.7 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KIK52202.1 - 0.0039 17.7 9.6 0.0039 17.7 9.6 4.6 1 1 3 4 4 4 2 Apg6 coiled-coil region Csm1_N PF18504.1 KIK52202.1 - 0.011 16.1 0.4 0.011 16.1 0.4 6.9 4 2 2 6 6 6 0 Csm1 N-terminal domain DUF5082 PF16888.5 KIK52202.1 - 0.13 12.5 35.7 0.96 9.7 9.3 6.0 2 1 3 5 5 5 0 Domain of unknown function (DUF5082) zf-C4H2 PF10146.9 KIK52202.1 - 0.32 11.3 27.1 0.17 12.2 0.5 3.4 1 1 1 2 2 1 0 Zinc finger-containing protein Atg14 PF10186.9 KIK52202.1 - 0.93 8.5 37.7 0.29 10.2 14.8 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 KIK52202.1 - 1.3 9.6 13.9 5.7 7.5 0.0 5.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KIK52202.1 - 1.5 8.2 46.8 0.13 11.6 5.8 4.1 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KIK52202.1 - 1.6 8.6 44.3 0.71 9.7 1.1 7.7 4 3 4 8 8 8 0 Septum formation initiator DASH_Dam1 PF08653.10 KIK52202.1 - 2.4 8.0 3.8 24 4.8 0.1 4.3 5 0 0 5 5 5 0 DASH complex subunit Dam1 ZapB PF06005.12 KIK52202.1 - 6.4 7.3 42.7 0.96 9.9 5.9 6.6 2 2 3 6 6 6 0 Cell division protein ZapB Fez1 PF06818.15 KIK52202.1 - 7.6 6.9 46.2 42 4.5 11.0 3.8 1 1 2 3 3 3 0 Fez1 WD40 PF00400.32 KIK52203.1 - 1.7e-25 88.7 18.6 2.1e-06 28.4 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52203.1 - 4.7e-07 30.0 1.4 0.57 10.5 0.1 4.2 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain YadA_stalk PF05662.14 KIK52203.1 - 0.00014 22.2 0.0 1.1 9.6 0.0 3.5 3 0 0 3 3 3 1 Coiled stalk of trimeric autotransporter adhesin PQQ_2 PF13360.6 KIK52203.1 - 0.00032 20.4 1.1 0.15 11.6 0.1 3.1 1 1 0 1 1 1 1 PQQ-like domain PALB2_WD40 PF16756.5 KIK52203.1 - 0.0013 17.7 1.8 3.8 6.3 0.1 3.5 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 KIK52203.1 - 0.0017 18.2 0.1 0.68 10.0 0.0 4.0 4 0 0 4 4 4 1 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIK52203.1 - 0.0028 16.6 0.0 1.4 7.8 0.0 2.3 1 1 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) PQQ_3 PF13570.6 KIK52203.1 - 0.0096 16.4 1.7 3 8.4 0.0 3.9 3 1 0 3 3 3 1 PQQ-like domain Frtz PF11768.8 KIK52203.1 - 0.015 13.6 0.5 5.6 5.2 0.0 2.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK52203.1 - 0.042 12.4 0.1 0.11 11.0 0.1 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Gmad1 PF10647.9 KIK52203.1 - 0.043 13.6 0.0 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PLD_C PF12357.8 KIK52203.1 - 0.077 12.9 0.1 38 4.3 0.0 3.1 2 1 1 3 3 3 0 Phospholipase D C terminal PT-TG PF14449.6 KIK52203.1 - 0.081 12.8 0.1 77 3.3 0.0 3.8 4 0 0 4 4 4 0 Pre-toxin TG PepSY PF03413.19 KIK52203.1 - 0.18 12.4 0.1 1.4e+02 3.2 0.0 3.8 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain GILT PF03227.16 KIK52204.1 - 0.0047 17.2 0.5 0.0079 16.4 0.5 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) COMM_domain PF07258.14 KIK52204.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.6 1 1 0 1 1 1 0 COMM domain KDZ PF18758.1 KIK52205.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK52206.1 - 1e-24 86.8 1.4 1e-24 86.8 1.4 1.6 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK52206.1 - 0.00074 19.6 1.4 0.0012 18.9 1.4 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Myb_DNA-binding PF00249.31 KIK52207.1 - 6.5e-29 99.9 7.4 2.2e-09 37.4 0.2 3.6 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK52207.1 - 2.2e-21 75.8 1.3 1.1e-11 44.8 0.3 3.4 2 2 1 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KIK52207.1 - 0.0039 17.3 1.3 0.97 9.7 0.1 2.6 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KIK52207.1 - 0.0065 16.5 0.3 0.74 9.9 0.2 3.0 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 KIK52207.1 - 0.097 12.6 0.0 2.9 7.9 0.0 2.5 3 0 0 3 3 3 0 Myb DNA-binding like Cobl PF09469.10 KIK52209.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Cauli_VI PF01693.16 KIK52210.1 - 0.00079 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DNA_topoisoIV PF00521.20 KIK52213.1 - 5e-71 239.8 6.5 9.7e-63 212.5 4.4 3.1 2 2 1 3 3 3 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIK52213.1 - 4.9e-30 104.4 8.7 5.5e-30 104.3 4.0 3.2 2 1 0 2 2 2 1 C-terminal associated domain of TOPRIM HATPase_c PF02518.26 KIK52213.1 - 9.8e-06 26.1 0.1 2.7e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAP65_ASE1 PF03999.12 KIK52215.1 - 0.0013 17.5 10.3 0.0015 17.3 10.3 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) HMMR_N PF15905.5 KIK52215.1 - 0.0037 16.8 12.7 0.059 12.8 2.6 2.0 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 KIK52215.1 - 0.032 14.9 10.3 0.081 13.6 2.1 2.5 2 1 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KIK52215.1 - 0.15 12.1 16.0 0.88 9.6 8.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mei5 PF10376.9 KIK52215.1 - 0.23 11.3 8.6 0.39 10.6 8.6 1.5 1 1 0 1 1 1 0 Double-strand recombination repair protein DivIVA PF05103.13 KIK52215.1 - 0.47 10.5 7.1 2.9 8.0 0.2 2.7 2 1 0 2 2 2 0 DivIVA protein Enkurin PF13864.6 KIK52215.1 - 0.5 10.8 5.3 0.8 10.2 2.0 2.8 1 1 1 2 2 2 0 Calmodulin-binding DUF1664 PF07889.12 KIK52215.1 - 0.59 10.2 6.6 6.6 6.8 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dad3 PF08656.10 KIK52215.1 - 0.7 10.0 4.7 1.5 8.9 1.2 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad3 Tup_N PF08581.10 KIK52215.1 - 0.72 10.2 9.2 5.1 7.5 0.2 2.7 2 1 1 3 3 3 0 Tup N-terminal DUF16 PF01519.16 KIK52215.1 - 0.76 10.3 10.1 25 5.4 7.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3461 PF11944.8 KIK52215.1 - 0.77 9.9 4.9 0.79 9.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) DivIC PF04977.15 KIK52215.1 - 0.81 9.5 7.0 11 5.9 0.1 3.2 2 2 1 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.22 KIK52215.1 - 0.82 9.9 6.8 2.3 8.5 0.1 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.11 KIK52215.1 - 0.89 10.4 15.9 5.6 7.9 1.6 3.0 1 1 0 2 2 2 0 Rho Binding Med9 PF07544.13 KIK52215.1 - 0.9 9.7 6.8 7.2 6.8 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sec2p PF06428.11 KIK52215.1 - 0.96 9.5 12.1 0.49 10.4 2.1 2.9 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF4201 PF13870.6 KIK52215.1 - 1.1 8.9 12.0 3.9 7.2 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HALZ PF02183.18 KIK52215.1 - 1.1 9.5 7.3 3.8 7.8 1.0 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.8 KIK52215.1 - 1.2 8.4 10.9 2.4 7.4 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) SKA1 PF07160.12 KIK52215.1 - 1.3 8.8 9.9 1.7 8.5 1.6 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Fungal_TACC PF12709.7 KIK52215.1 - 1.3 9.5 10.6 0.38 11.2 0.5 3.2 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 KIK52215.1 - 1.6 9.2 14.1 0.9 10.0 4.4 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF745 PF05335.13 KIK52215.1 - 5.9 6.6 12.5 8.5 6.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sec34 PF04136.15 KIK52215.1 - 7.9 6.3 11.0 1.1 9.1 4.2 2.3 1 1 1 2 2 2 0 Sec34-like family HTH_Tnp_Mu_2 PF09039.11 KIK52219.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 Mu DNA binding, I gamma subdomain TSC22 PF01166.18 KIK52222.1 - 0.0011 19.2 7.4 0.24 11.7 0.0 3.5 3 2 1 4 4 4 2 TSC-22/dip/bun family FapA PF03961.13 KIK52222.1 - 0.003 16.2 3.6 0.004 15.8 3.6 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF4279 PF14106.6 KIK52222.1 - 0.0055 16.9 0.9 0.16 12.2 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4279) DUF2203 PF09969.9 KIK52222.1 - 0.013 16.3 6.0 0.092 13.5 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Jnk-SapK_ap_N PF09744.9 KIK52222.1 - 0.013 15.7 12.7 0.51 10.5 3.6 2.3 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CDC37_N PF03234.14 KIK52222.1 - 0.021 15.8 2.0 0.078 13.9 2.0 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding ZapB PF06005.12 KIK52222.1 - 0.022 15.2 1.6 0.022 15.2 1.6 2.8 2 1 0 2 2 2 0 Cell division protein ZapB TetR_C_13 PF16925.5 KIK52222.1 - 0.034 14.1 1.3 0.11 12.4 0.3 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YPEB PF14620.6 KIK52222.1 - 0.046 13.1 4.4 0.12 11.8 4.0 1.7 1 1 0 1 1 1 0 YpeB sporulation AAA_13 PF13166.6 KIK52222.1 - 0.061 12.0 4.4 0.078 11.6 4.4 1.1 1 0 0 1 1 1 0 AAA domain MCD_N PF17408.2 KIK52222.1 - 0.066 13.4 0.9 0.49 10.6 0.1 2.6 1 1 2 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain Spc7 PF08317.11 KIK52222.1 - 0.09 11.6 12.2 0.087 11.7 2.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KIK52222.1 - 0.09 13.1 11.5 2.5 8.5 3.4 3.5 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 KIK52222.1 - 0.11 12.5 13.2 0.67 10.0 0.3 3.1 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.8 KIK52222.1 - 0.14 12.6 9.5 1.5 9.2 2.0 2.1 2 0 0 2 2 2 0 YlqD protein Cep57_MT_bd PF06657.13 KIK52222.1 - 0.17 12.4 7.0 0.1 13.1 1.9 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FUSC PF04632.12 KIK52222.1 - 0.17 10.4 2.1 0.23 10.0 1.9 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 KIK52222.1 - 0.22 10.8 8.8 0.62 9.3 8.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 KIK52222.1 - 0.22 11.8 6.3 1.7 8.9 1.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Cep57_CLD_2 PF14197.6 KIK52222.1 - 0.24 11.5 11.0 0.28 11.3 0.7 3.2 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Lectin_N PF03954.14 KIK52222.1 - 0.25 11.1 7.7 0.35 10.6 1.4 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_p24 PF05073.12 KIK52222.1 - 0.25 11.1 5.1 0.86 9.4 0.8 2.1 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Syntaxin_2 PF14523.6 KIK52222.1 - 0.35 11.3 6.4 2 8.8 0.4 2.7 1 1 1 2 2 2 0 Syntaxin-like protein Spc29 PF17082.5 KIK52222.1 - 0.35 10.7 4.4 0.94 9.3 0.9 2.0 1 1 0 2 2 2 0 Spindle Pole Component 29 ACCA PF03255.14 KIK52222.1 - 0.38 10.6 3.1 0.49 10.3 0.2 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spectrin PF00435.21 KIK52222.1 - 0.41 11.2 9.4 3.9 8.0 0.9 2.6 1 1 2 3 3 3 0 Spectrin repeat Baculo_PEP_C PF04513.12 KIK52222.1 - 0.42 10.7 7.6 11 6.1 0.1 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 KIK52222.1 - 0.44 10.3 12.9 0.034 13.9 4.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fez1 PF06818.15 KIK52222.1 - 0.56 10.6 10.5 5.5 7.4 10.5 2.2 1 1 0 1 1 1 0 Fez1 HAUS-augmin3 PF14932.6 KIK52222.1 - 0.74 9.3 13.9 2.8 7.5 1.9 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Lebercilin PF15619.6 KIK52222.1 - 0.86 9.2 12.2 2.4 7.8 0.4 3.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlgN PF05130.12 KIK52222.1 - 1.4 9.5 11.0 0.41 11.2 6.1 2.0 1 1 1 2 2 2 0 FlgN protein OmpH PF03938.14 KIK52222.1 - 1.6 9.1 13.4 8.8e+02 0.2 13.4 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 KIK52222.1 - 3 7.9 9.1 0.27 11.2 3.5 2.1 1 1 1 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.22 KIK52222.1 - 3.1 8.0 14.2 3.5 7.9 4.8 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Bap31_Bap29_C PF18035.1 KIK52222.1 - 4.3 7.4 14.3 2.5 8.2 0.7 3.5 4 1 0 4 4 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Swi5 PF07061.11 KIK52222.1 - 5.8 7.1 13.2 22 5.2 0.6 3.6 1 1 1 2 2 2 0 Swi5 TPR_MLP1_2 PF07926.12 KIK52222.1 - 6.2 6.9 16.2 0.72 9.9 4.6 2.8 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 KIK52222.1 - 6.3 7.3 7.7 20 5.7 0.1 3.4 3 2 1 4 4 4 0 Lipoprotein leucine-zipper CC2-LZ PF16516.5 KIK52222.1 - 7.2 7.1 11.7 0.8 10.1 1.6 2.9 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Cmyb_C PF09316.10 KIK52223.1 - 0.031 14.0 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 C-myb, C-terminal AIG1 PF04548.16 KIK52224.1 - 8.1e-10 38.4 0.4 8.1e-10 38.4 0.4 2.0 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KIK52224.1 - 3.2e-07 30.6 5.2 0.0058 16.7 0.0 3.3 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 KIK52224.1 - 4.2e-07 30.0 0.1 4.2e-07 30.0 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK52224.1 - 1.9e-05 24.6 1.2 0.00026 20.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KIK52224.1 - 0.00017 22.2 5.9 0.0011 19.6 4.1 2.0 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.11 KIK52224.1 - 0.0016 17.4 12.1 0.0024 16.8 12.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 KIK52224.1 - 0.0037 16.6 9.4 0.0056 16.1 9.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FAM76 PF16046.5 KIK52224.1 - 0.0043 16.5 4.0 0.0054 16.1 4.0 1.1 1 0 0 1 1 1 1 FAM76 protein DUF1640 PF07798.11 KIK52224.1 - 0.0046 17.0 6.5 0.0069 16.4 6.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 KIK52224.1 - 0.014 14.8 6.3 0.019 14.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMMR_N PF15905.5 KIK52224.1 - 0.014 14.9 9.4 0.019 14.4 9.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KIK52224.1 - 0.019 15.1 5.7 0.026 14.6 5.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TubC_N PF18563.1 KIK52224.1 - 0.021 14.8 0.1 0.11 12.5 0.1 2.2 1 0 0 1 1 1 0 TubC N-terminal docking domain FeoB_N PF02421.18 KIK52224.1 - 0.066 12.7 0.8 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF641 PF04859.12 KIK52224.1 - 0.09 13.1 5.2 0.15 12.4 5.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Uso1_p115_C PF04871.13 KIK52224.1 - 0.092 13.1 9.7 0.16 12.4 9.7 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region YtxH PF12732.7 KIK52224.1 - 0.12 13.0 4.8 0.28 11.7 4.8 1.6 1 0 0 1 1 1 0 YtxH-like protein ADIP PF11559.8 KIK52224.1 - 0.12 12.4 11.0 0.18 11.9 11.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KIK52224.1 - 0.4 10.1 14.2 1.2 8.5 14.5 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 FlxA PF14282.6 KIK52224.1 - 0.49 10.4 18.7 8.4 6.5 18.7 2.1 1 1 0 1 1 1 0 FlxA-like protein Fzo_mitofusin PF04799.13 KIK52224.1 - 0.52 9.8 7.5 1.3 8.6 7.2 1.8 1 1 1 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 KIK52224.1 - 0.57 10.4 8.9 2 8.6 1.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 KIK52224.1 - 0.64 9.3 10.2 0.93 8.7 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 KIK52224.1 - 0.73 10.2 15.1 1.4 9.4 15.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.10 KIK52224.1 - 0.75 10.0 10.7 1.8 8.8 10.7 1.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil HAUS6_N PF14661.6 KIK52224.1 - 0.86 9.1 7.5 1.3 8.6 7.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4795 PF16043.5 KIK52224.1 - 1.3 8.6 13.9 4.7 6.7 13.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF724 PF05266.14 KIK52224.1 - 2.1 8.1 11.1 3.2 7.5 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Mod_r PF07200.13 KIK52224.1 - 2.5 8.2 12.7 8.1 6.5 12.7 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2203 PF09969.9 KIK52224.1 - 5 7.9 8.7 3.4 8.4 3.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2408 PF10303.9 KIK52224.1 - 5.3 7.6 9.6 48 4.5 9.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Atg14 PF10186.9 KIK52224.1 - 5.6 5.9 9.9 8.2 5.4 9.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KIK52224.1 - 6.8 5.8 8.1 10 5.3 8.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1635 PF07795.11 KIK52224.1 - 8.8 6.1 11.7 0.25 11.2 5.7 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1635) HSCB_C PF07743.13 KIK52224.1 - 10 6.7 12.4 6.1 7.4 9.0 2.4 2 1 0 2 2 1 0 HSCB C-terminal oligomerisation domain Phage_head_chap PF11113.8 KIK52225.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Head assembly gene product Ank_3 PF13606.6 KIK52231.1 - 2e-08 33.8 1.3 0.076 13.6 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KIK52231.1 - 5.3e-08 33.2 0.0 0.11 13.1 0.1 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK52231.1 - 1.3e-05 25.7 0.0 0.0042 17.6 0.0 3.3 2 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK52231.1 - 0.0021 18.4 5.7 0.78 10.3 0.1 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KIK52231.1 - 0.035 14.4 0.0 0.8 10.1 0.1 3.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK52232.1 - 4e-22 78.3 9.9 1.7e-08 34.9 0.1 7.9 9 0 0 9 9 9 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KIK52232.1 - 1.4e-21 77.0 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KIK52232.1 - 1.6e-21 76.7 1.9 8.2e-07 29.5 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK52232.1 - 1.2e-19 68.3 6.6 0.023 15.2 0.0 9.2 8 0 0 8 8 8 4 Ankyrin repeat Pkinase PF00069.25 KIK52232.1 - 2.7e-19 69.5 0.0 4.7e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 KIK52232.1 - 5.7e-11 42.4 2.8 0.023 15.0 0.0 5.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK52232.1 - 0.00037 20.8 16.7 12 6.6 0.1 8.4 9 1 0 9 9 9 2 Ankyrin repeat Sel1 PF08238.12 KIK52232.1 - 0.053 14.2 2.4 12 6.7 0.2 3.1 2 0 0 2 2 2 0 Sel1 repeat TIP41 PF04176.13 KIK52232.1 - 0.16 11.4 0.2 58 3.1 0.0 3.1 3 0 0 3 3 3 0 TIP41-like family Fer4_12 PF13353.6 KIK52232.1 - 1.2 9.4 9.2 49 4.2 0.1 4.0 4 0 0 4 4 4 0 4Fe-4S single cluster domain SopE_GEF PF07487.13 KIK52234.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain Endonuc-PvuII PF09225.10 KIK52235.1 - 0.13 12.0 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII Chromo PF00385.24 KIK52236.1 - 0.00055 19.8 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1859 PF08948.10 KIK52236.1 - 0.04 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) CPW_WPC PF09717.10 KIK52237.1 - 0.31 12.1 5.1 0.37 11.8 5.1 1.4 1 1 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Cauli_VI PF01693.16 KIK52238.1 - 0.02 15.2 0.1 0.029 14.6 0.1 1.3 1 0 0 1 1 1 0 Caulimovirus viroplasmin Cauli_VI PF01693.16 KIK52239.1 - 0.00019 21.7 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pkinase PF00069.25 KIK52243.1 - 2.1e-15 56.8 0.0 2.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK52243.1 - 9.4e-15 54.6 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK52243.1 - 0.0056 16.1 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YchF-GTPase_C PF06071.13 KIK52243.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Alpha_kinase PF02816.18 KIK52247.1 - 3.4e-15 56.7 1.5 3.9e-15 56.5 1.5 1.0 1 0 0 1 1 1 1 Alpha-kinase family DUF640 PF04852.12 KIK52247.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF640) WD40 PF00400.32 KIK52249.1 - 1.3e-57 190.4 34.4 9.8e-11 42.0 0.4 11.2 10 1 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52249.1 - 5.9e-31 106.6 0.5 0.036 14.4 0.0 10.6 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK52249.1 - 3.4e-15 55.5 9.6 0.0026 17.7 0.1 8.5 10 0 0 10 10 10 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK52249.1 - 1.2e-13 50.8 6.5 0.093 11.7 0.0 8.3 2 1 8 11 11 11 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK52249.1 - 8.1e-13 47.5 0.0 0.0034 15.8 0.0 5.0 4 1 1 5 5 5 4 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK52249.1 - 3.5e-08 33.1 6.3 5.7 6.2 0.0 8.2 2 2 6 9 9 9 3 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KIK52249.1 - 0.00019 20.1 1.4 0.12 10.9 0.0 3.5 1 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 KIK52249.1 - 0.0047 15.6 3.4 2.2 6.8 0.1 4.8 4 2 1 6 6 6 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIK52249.1 - 0.0062 15.5 2.8 1.7 7.5 0.0 3.8 5 1 1 6 6 6 2 Partner and localizer of BRCA2 WD40 domain WD40_3 PF15911.5 KIK52249.1 - 0.0099 15.9 1.0 1.7 8.7 0.0 4.3 3 2 2 5 5 5 1 WD domain, G-beta repeat tify PF06200.14 KIK52249.1 - 0.082 12.2 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 tify domain Utp8 PF10395.9 KIK52249.1 - 0.24 9.8 0.0 26 3.1 0.0 3.2 3 1 1 4 4 4 0 Utp8 family rOmpB PF12334.8 KIK52249.1 - 5.8 6.3 7.6 12 5.3 0.2 3.8 5 0 0 5 5 5 0 Rickettsia outer membrane protein B WD40 PF00400.32 KIK52253.1 - 8.4e-52 172.0 59.0 2.7e-10 40.6 0.3 16.7 14 3 0 14 14 14 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52253.1 - 2.6e-37 127.0 0.2 0.042 14.2 0.0 13.5 2 2 11 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK52253.1 - 2.7e-15 56.6 8.8 3.2e-06 26.9 0.2 5.7 1 1 2 5 5 5 2 PQQ-like domain PD40 PF07676.12 KIK52253.1 - 1.6e-11 43.8 30.2 0.26 11.3 0.0 13.6 17 0 0 17 17 17 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK52253.1 - 1.4e-10 40.7 15.4 0.32 9.9 0.0 11.1 4 3 5 12 12 12 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK52253.1 - 3.8e-08 32.1 0.0 0.12 10.7 0.0 5.3 6 0 0 6 6 6 3 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK52253.1 - 2.8e-06 26.9 12.3 6.5 6.0 0.0 10.0 4 3 8 14 14 14 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK52253.1 - 5.6e-06 25.3 4.0 0.075 11.7 0.0 5.3 3 2 2 6 6 6 2 Nucleoporin Nup120/160 PQQ PF01011.21 KIK52253.1 - 0.00012 21.9 0.0 24 5.1 0.1 6.2 5 0 0 5 5 5 0 PQQ enzyme repeat Gmad1 PF10647.9 KIK52253.1 - 0.00025 20.9 3.7 1.5 8.5 0.0 6.1 5 2 0 5 5 5 1 Lipoprotein LpqB beta-propeller domain YadA_stalk PF05662.14 KIK52253.1 - 0.0044 17.3 2.4 4.7 7.7 0.1 3.3 3 0 0 3 3 3 2 Coiled stalk of trimeric autotransporter adhesin DUF3313 PF11769.8 KIK52253.1 - 0.0046 16.8 0.2 22 4.8 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3313) Lactonase PF10282.9 KIK52253.1 - 0.03 13.6 0.0 0.35 10.1 0.0 2.7 3 1 1 4 4 4 0 Lactonase, 7-bladed beta-propeller Proteasome_A_N PF10584.9 KIK52253.1 - 5.1 6.9 11.5 20 4.9 0.0 6.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK52256.1 - 2.1e-24 85.3 30.9 2.9e-07 31.1 2.9 10.7 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52256.1 - 8.3e-23 80.5 0.1 0.08 13.3 0.0 9.3 2 2 7 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK52256.1 - 1.1e-09 38.3 1.4 2.1e-08 34.0 0.3 3.1 1 1 2 3 3 3 2 PQQ-like domain NACHT PF05729.12 KIK52256.1 - 1.1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK52256.1 - 2e-08 33.9 3.3 0.61 10.1 0.1 7.8 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK52256.1 - 2.3e-05 23.5 6.1 10 5.0 0.0 7.1 3 2 4 8 8 8 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK52256.1 - 0.00011 21.7 3.5 5 6.4 0.0 6.4 4 1 2 8 8 8 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK52256.1 - 0.00033 19.1 0.0 0.67 8.2 0.0 2.5 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK52256.1 - 0.0008 18.2 0.1 0.12 11.0 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 NB-ARC PF00931.22 KIK52256.1 - 0.0099 15.1 0.0 0.19 10.9 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain WD40_3 PF15911.5 KIK52256.1 - 0.032 14.2 0.0 0.14 12.2 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat AAA_29 PF13555.6 KIK52256.1 - 0.04 13.7 1.3 5 7.0 0.1 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK52256.1 - 0.044 14.2 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KIK52256.1 - 0.1 13.1 0.2 1 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain PALB2_WD40 PF16756.5 KIK52256.1 - 0.11 11.5 1.8 1.3 7.8 0.1 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain APS_kinase PF01583.20 KIK52256.1 - 0.17 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.32 KIK52257.1 - 5.2e-32 109.4 31.8 1.1e-07 32.4 0.3 10.6 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52257.1 - 1.1e-22 80.2 1.3 0.039 14.3 0.0 8.6 2 2 7 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK52257.1 - 1.3e-14 53.9 2.5 0.08 11.9 0.0 7.4 2 2 7 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK52257.1 - 4.7e-12 45.5 7.9 1.7 8.7 0.2 9.8 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK52257.1 - 5.4e-07 28.3 0.1 0.013 13.8 0.0 3.3 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK52257.1 - 8.5e-06 24.7 3.4 0.05 12.3 0.9 4.9 3 2 3 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK52257.1 - 2.9e-05 24.1 0.2 5.5 6.8 0.2 4.4 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A POLO_box PF00659.18 KIK52257.1 - 0.0037 17.4 0.4 0.76 10.0 0.0 4.1 5 0 0 5 5 4 1 POLO box duplicated region FlaE PF07559.14 KIK52257.1 - 0.017 15.7 0.4 0.32 11.6 0.4 2.7 1 1 0 1 1 1 0 Flagellar basal body protein FlaE Utp8 PF10395.9 KIK52257.1 - 0.029 12.9 0.0 3.6 6.0 0.0 2.9 2 2 1 4 4 4 0 Utp8 family 3-dmu-9_3-mt PF06983.13 KIK52257.1 - 0.072 13.6 0.0 1.1e+02 3.4 0.0 4.1 4 1 1 5 5 5 0 3-demethylubiquinone-9 3-methyltransferase Transposase_21 PF02992.14 KIK52262.1 - 7.2e-06 25.4 0.7 1.5e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 Csm1_N PF18504.1 KIK52263.1 - 0.0037 17.6 20.4 0.39 11.1 1.7 4.4 3 1 1 4 4 4 2 Csm1 N-terminal domain HMMR_N PF15905.5 KIK52263.1 - 0.0039 16.7 14.1 0.22 10.9 1.3 2.4 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal DUF1635 PF07795.11 KIK52263.1 - 0.0046 16.9 8.0 0.17 11.7 0.4 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1635) DUF641 PF04859.12 KIK52263.1 - 0.0062 16.9 14.7 0.81 10.0 3.5 3.9 2 1 0 3 3 2 2 Plant protein of unknown function (DUF641) Fez1 PF06818.15 KIK52263.1 - 0.017 15.6 16.5 0.37 11.2 6.0 2.3 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KIK52263.1 - 0.029 13.3 22.3 0.05 12.5 9.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 KIK52263.1 - 0.048 12.6 11.2 0.078 11.9 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Phage_GP20 PF06810.11 KIK52263.1 - 0.13 12.1 12.0 2.5 7.9 0.4 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 HIP1_clath_bdg PF16515.5 KIK52263.1 - 0.15 12.7 17.0 0.48 11.0 3.0 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KASH_CCD PF14662.6 KIK52263.1 - 0.15 11.8 20.6 0.24 11.2 8.9 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2460 PF09343.10 KIK52263.1 - 0.23 11.0 0.9 10 5.6 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical protein 2217 (DUF2460) Med30 PF11315.8 KIK52263.1 - 0.27 11.4 4.7 14 5.9 1.7 2.6 2 0 0 2 2 2 0 Mediator complex subunit 30 Peptidase_S49_N PF08496.10 KIK52263.1 - 0.35 10.9 3.5 0.23 11.5 0.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Rho_Binding PF08912.11 KIK52263.1 - 0.43 11.4 12.7 2.8 8.8 0.9 3.4 3 0 0 3 3 3 0 Rho Binding Bacillus_HBL PF05791.11 KIK52263.1 - 0.44 10.3 4.9 1 9.2 1.1 2.6 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.8 KIK52263.1 - 0.44 10.6 23.0 0.41 10.7 4.9 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding XLF PF09302.11 KIK52263.1 - 0.85 9.8 4.1 7.4 6.7 0.2 3.1 2 2 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component HemX PF04375.14 KIK52263.1 - 0.92 8.7 13.2 1.8 7.8 1.9 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cauli_AT PF03233.13 KIK52263.1 - 0.94 9.4 6.9 0.93 9.4 0.3 3.1 1 1 2 3 3 3 0 Aphid transmission protein DUF745 PF05335.13 KIK52263.1 - 0.95 9.2 11.2 2.8 7.6 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Herpes_ICP4_N PF03584.15 KIK52263.1 - 0.97 9.3 2.9 8.5 6.2 0.2 2.3 1 1 1 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region DUF4201 PF13870.6 KIK52263.1 - 1 9.1 13.4 3.3 7.4 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Spc42p PF11544.8 KIK52263.1 - 1.9 8.5 5.0 16 5.6 0.0 3.8 2 2 0 4 4 4 0 Spindle pole body component Spc42p PKcGMP_CC PF16808.5 KIK52263.1 - 2.4 8.1 27.8 1 9.2 0.3 5.6 6 1 0 6 6 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CC2-LZ PF16516.5 KIK52263.1 - 2.8 8.4 17.9 2.6 8.5 1.9 3.4 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TolA_bind_tri PF16331.5 KIK52263.1 - 3.7 7.7 12.9 6.9 6.8 0.4 3.5 2 2 0 2 2 2 0 TolA binding protein trimerisation ATG16 PF08614.11 KIK52263.1 - 3.8 7.7 24.5 1.1 9.5 6.0 2.8 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FtsX_ECD PF18075.1 KIK52263.1 - 5.8 7.6 7.9 2.1 9.0 1.6 2.5 1 1 1 2 2 2 0 FtsX extracellular domain AAA_13 PF13166.6 KIK52263.1 - 6.7 5.2 13.0 0.9 8.1 3.0 2.0 1 1 0 2 2 2 0 AAA domain ADIP PF11559.8 KIK52263.1 - 7 6.7 16.7 1.3 9.1 3.7 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Casc1_N PF15927.5 KIK52263.1 - 7.8 6.1 22.7 1.9 8.1 4.0 3.0 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus DUF16 PF01519.16 KIK52263.1 - 10 6.7 8.7 9.6 6.8 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF648 PF04890.13 KIK52264.1 - 0.0065 16.3 0.4 0.009 15.8 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF648) DUF745 PF05335.13 KIK52264.1 - 0.077 12.7 3.9 1.1 8.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK52264.1 - 0.74 9.7 4.3 3 7.8 0.3 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TFIIA PF03153.13 KIK52267.1 - 4.6 7.1 9.8 5.3 6.9 9.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Inhibitor_I66 PF16850.5 KIK52268.1 - 5.4e-29 100.9 0.0 3.4e-28 98.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I66 Inhibitor_I66 PF16850.5 KIK52269.1 - 5.1e-16 58.8 0.0 5.5e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 PRP1_N PF06424.12 KIK52271.1 - 0.13 12.7 1.2 5.1 7.5 0.1 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal AAA_16 PF13191.6 KIK52272.1 - 0.0004 20.8 0.0 0.0004 20.8 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK52272.1 - 0.00054 19.9 0.0 0.00054 19.9 0.0 1.0 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK52272.1 - 0.00055 20.3 0.0 0.00055 20.3 0.0 1.1 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 KIK52272.1 - 0.0013 17.9 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 KIK52272.1 - 0.0045 16.8 0.0 0.0047 16.7 0.0 1.0 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KIK52272.1 - 0.0045 16.7 0.0 0.0049 16.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIK52272.1 - 0.0064 16.4 0.0 0.0069 16.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase Mg_chelatase PF01078.21 KIK52272.1 - 0.0071 15.8 0.0 0.0079 15.6 0.0 1.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KIK52272.1 - 0.0074 16.0 0.0 0.0074 16.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KIK52272.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KIK52272.1 - 0.015 15.9 0.0 0.015 15.9 0.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK52272.1 - 0.016 15.5 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK52272.1 - 0.016 14.8 0.0 0.016 14.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK52272.1 - 0.024 14.4 0.0 0.025 14.3 0.0 1.0 1 0 0 1 1 1 0 Cytidylate kinase AAA PF00004.29 KIK52272.1 - 0.024 15.0 0.0 0.024 15.0 0.0 1.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIK52272.1 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KIK52272.1 - 0.053 12.7 0.0 0.053 12.7 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 KIK52272.1 - 0.053 13.0 0.0 0.061 12.8 0.0 1.0 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KIK52272.1 - 0.058 13.9 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KIK52272.1 - 0.069 12.7 0.0 0.069 12.7 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2791 PF10923.8 KIK52272.1 - 0.078 11.8 0.0 0.078 11.8 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_5 PF07728.14 KIK52272.1 - 0.095 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK52272.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIK52272.1 - 0.17 12.0 0.1 0.18 12.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIK52272.1 - 0.17 11.5 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.15 KIK52272.1 - 0.19 11.6 0.0 0.2 11.5 0.0 1.0 1 0 0 1 1 1 0 NTPase Sigma54_activ_2 PF14532.6 KIK52272.1 - 0.2 11.8 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_PrkA PF08298.11 KIK52272.1 - 0.2 10.5 0.0 0.21 10.5 0.0 1.0 1 0 0 1 1 1 0 PrkA AAA domain Glycos_transf_2 PF00535.26 KIK52274.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 NACHT PF05729.12 KIK52275.1 - 3.7e-08 33.5 0.0 4.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK52275.1 - 9.5e-05 22.8 0.0 0.00013 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK52275.1 - 0.0012 19.2 0.1 0.0022 18.4 0.1 1.7 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIK52275.1 - 0.005 17.1 0.0 0.0075 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KIK52275.1 - 0.0058 15.8 0.2 0.0084 15.2 0.2 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK52275.1 - 0.0065 16.9 0.2 0.032 14.6 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK52275.1 - 0.023 14.4 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK52275.1 - 0.025 14.3 0.5 0.15 11.8 0.2 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KIK52275.1 - 0.035 13.9 0.0 0.066 12.9 0.0 1.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_18 PF13238.6 KIK52275.1 - 0.047 14.2 0.0 0.051 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK52275.1 - 0.048 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_24 PF18109.1 KIK52275.1 - 0.076 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain ATP_bind_1 PF03029.17 KIK52275.1 - 0.12 12.2 0.1 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KIK52275.1 - 0.12 12.0 0.4 1.4 8.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK52275.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSM_b PF10741.9 KIK52275.1 - 0.15 11.8 0.2 0.57 10.0 0.0 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b AAA_30 PF13604.6 KIK52275.1 - 0.16 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK52275.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Retrotran_gag_2 PF14223.6 KIK52276.1 - 8.2e-11 41.7 0.0 1.9e-10 40.5 0.0 1.6 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIK52276.1 - 0.00074 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Hormone_3 PF00159.18 KIK52278.1 - 0.031 14.3 0.3 0.061 13.4 0.3 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide STE3 PF02076.15 KIK52279.1 - 7.6e-81 271.5 23.1 9.1e-81 271.2 23.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KIK52280.1 - 5.2e-81 272.0 20.8 6.1e-81 271.8 20.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KIK52281.1 - 3.3e-83 279.3 19.6 3.7e-83 279.1 19.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor Arylsulfotran_2 PF14269.6 KIK52282.1 - 7.4e-54 183.1 1.6 9.7e-54 182.8 1.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) RHS PF03527.14 KIK52282.1 - 0.063 13.0 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 RHS protein Arylsulfotran_2 PF14269.6 KIK52283.1 - 2.4e-51 174.9 2.9 3.1e-49 167.9 2.9 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) CBM26 PF16738.5 KIK52283.1 - 0.049 13.9 0.4 0.13 12.5 0.4 1.7 1 0 0 1 1 1 0 Starch-binding module 26 GATA PF00320.27 KIK52285.1 - 1.4e-13 50.2 2.3 2.3e-13 49.5 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF4083 PF13314.6 KIK52290.1 - 1.7 8.7 7.5 3.8 7.5 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Spt20 PF12090.8 KIK52291.1 - 7.5e-19 68.3 0.6 3e-11 43.4 0.1 5.4 3 3 1 5 5 5 2 Spt20 family DUF383 PF04063.14 KIK52292.1 - 3.7e-57 193.1 0.0 8e-57 192.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KIK52292.1 - 1.7e-17 63.0 0.3 4e-17 61.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.22 KIK52292.1 - 0.055 13.7 0.0 0.24 11.8 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat NACHT PF05729.12 KIK52293.1 - 4.1e-09 36.6 0.1 6.7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK52293.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK52293.1 - 0.0015 18.8 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK52293.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KIK52293.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIK52293.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KIK52293.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_14 PF13173.6 KIK52293.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK52293.1 - 0.027 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIK52293.1 - 0.03 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK52293.1 - 0.043 13.1 0.1 0.084 12.1 0.1 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ResIII PF04851.15 KIK52293.1 - 0.044 13.8 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KIK52293.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KIK52293.1 - 0.061 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 KIK52293.1 - 0.064 13.0 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KIK52293.1 - 0.069 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KIK52293.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KIK52293.1 - 0.11 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KIK52293.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KIK52293.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 KIK52293.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AFG1_ATPase PF03969.16 KIK52293.1 - 0.19 10.6 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase Ank_2 PF12796.7 KIK52294.1 - 3.3e-40 136.6 38.8 1.3e-12 48.1 3.7 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK52294.1 - 7.6e-39 131.6 11.3 3e-07 30.9 0.0 8.3 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK52294.1 - 1.6e-28 95.6 19.1 0.0031 17.9 0.1 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 KIK52294.1 - 5.2e-28 96.2 35.3 0.0003 21.1 0.1 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 KIK52294.1 - 3.3e-08 33.6 14.2 0.024 15.0 0.2 7.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) RTC4 PF14474.6 KIK52294.1 - 0.00053 20.1 5.4 1.2 9.3 1.0 4.3 1 1 5 6 6 6 3 RTC4-like domain AlaE PF06610.13 KIK52294.1 - 0.0025 17.8 0.9 1.5 8.8 0.0 2.5 2 1 0 2 2 2 2 L-alanine exporter PAN_1 PF00024.26 KIK52295.1 - 0.016 15.2 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 KIK52296.1 - 0.0053 16.7 0.1 0.0092 15.9 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KIK52296.1 - 0.052 13.5 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 PAN domain Trypsin PF00089.26 KIK52298.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Trypsin DUF4470 PF14737.6 KIK52299.1 - 1.9e-05 24.8 0.1 0.00013 22.0 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4470) F-box-like PF12937.7 KIK52302.1 - 1.8e-05 24.5 0.1 5.1e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KIK52303.1 - 5.4e-21 74.9 55.3 2.9e-13 49.5 22.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TssN PF17555.2 KIK52303.1 - 0.14 11.5 3.9 0.3 10.4 3.9 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN E1-E2_ATPase PF00122.20 KIK52304.1 - 8e-45 152.6 3.2 1.2e-44 152.1 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK52304.1 - 8e-35 121.0 0.0 1.6e-34 120.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIK52304.1 - 6.4e-21 74.6 2.9 2.1e-08 34.5 0.6 3.7 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIK52304.1 - 0.00012 21.9 0.2 0.00026 20.8 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK52304.1 - 0.052 13.9 0.1 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Gly-zipper_Omp PF13488.6 KIK52305.1 - 5.3 7.1 5.2 12 6.0 5.2 1.5 1 0 0 1 1 1 0 Glycine zipper Methyltransf_25 PF13649.6 KIK52306.1 - 5.4e-06 27.0 0.0 1.5e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK52306.1 - 0.00022 21.8 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK52306.1 - 0.0023 17.7 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK52306.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK52306.1 - 0.012 16.3 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DNA_gyraseB_C PF00986.21 KIK52306.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus F-box-like PF12937.7 KIK52307.1 - 0.001 18.9 0.4 0.0096 15.8 0.4 2.3 1 1 0 1 1 1 1 F-box-like CK2S PF15011.6 KIK52307.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate Cep57_CLD_2 PF14197.6 KIK52307.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TPR_12 PF13424.6 KIK52307.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.7 KIK52309.1 - 0.011 15.6 2.5 0.065 13.1 2.5 2.2 1 1 0 1 1 1 0 F-box-like DinB_2 PF12867.7 KIK52309.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 DinB superfamily AhpC-TSA PF00578.21 KIK52311.1 - 2.6e-25 88.7 0.0 5.8e-25 87.6 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KIK52311.1 - 4.7e-16 58.8 0.0 6.7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KIK52311.1 - 0.034 14.3 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme FXR_C3 PF16097.5 KIK52311.1 - 0.099 13.3 3.0 0.66 10.7 3.0 2.2 1 1 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 F-box-like PF12937.7 KIK52313.1 - 6.1e-06 26.0 0.5 1.7e-05 24.6 0.5 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK52313.1 - 0.93 9.4 4.2 18 5.4 0.0 3.1 3 0 0 3 3 3 0 F-box domain Choline_kinase PF01633.20 KIK52314.1 - 0.00089 18.9 0.0 0.0019 17.8 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KIK52314.1 - 0.0055 16.7 0.0 0.3 11.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK52314.1 - 0.0092 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KIK52314.1 - 0.034 13.7 0.1 0.099 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KIK52314.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MHB PF16525.5 KIK52318.1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Haemophore, haem-binding ParA PF10609.9 KIK52319.1 - 1.5e-62 211.3 0.0 6.3e-62 209.2 0.0 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK52319.1 - 2e-10 40.8 0.0 8.4e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK52319.1 - 1.7e-06 27.4 0.1 0.0084 15.3 0.1 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 KIK52319.1 - 8.6e-06 25.8 0.9 0.00021 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KIK52319.1 - 0.00026 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ Choline_kinase PF01633.20 KIK52320.1 - 0.0021 17.7 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIK52320.1 - 0.0022 17.9 0.0 0.14 12.0 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK52320.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK52320.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 KIK52320.1 - 0.08 12.5 0.2 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Herpes_gI PF01688.17 KIK52322.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.6 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein I WaaY PF06176.11 KIK52323.1 - 9.9e-05 22.1 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KIK52323.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK52323.1 - 0.00019 21.1 0.1 0.00038 20.1 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KIK52323.1 - 0.0018 18.2 0.1 0.031 14.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK52323.1 - 0.0032 16.9 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Tnp_22_dsRBD PF17490.2 KIK52323.1 - 0.0097 15.9 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 L1 transposable element dsRBD-like domain Thioredoxin PF00085.20 KIK52323.1 - 0.2 11.6 0.3 0.63 10.1 0.2 1.8 2 0 0 2 2 2 0 Thioredoxin Flt3_lig PF02947.14 KIK52325.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 flt3 ligand DUF4419 PF14388.6 KIK52327.1 - 1.1e-113 379.6 0.0 1.3e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glyco_hydro_11 PF00457.17 KIK52328.1 - 2.6e-65 219.4 4.9 3e-65 219.2 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF2953 PF11167.8 KIK52328.1 - 0.085 12.9 0.2 0.45 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) F-box-like PF12937.7 KIK52329.1 - 0.0021 17.9 0.3 0.0064 16.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like Glyco_hydro_71 PF03659.14 KIK52330.1 - 0.01 14.7 0.1 0.023 13.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 RSRP PF17069.5 KIK52330.1 - 1.5 8.4 16.2 1.6 8.2 16.2 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDO_I PF05995.12 KIK52331.1 - 0.00022 20.6 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KIK52331.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 PCO_ADO PknG_rubred PF16919.5 KIK52334.1 - 0.025 14.7 0.1 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain ADIP PF11559.8 KIK52336.1 - 1.9e-24 86.5 4.7 1.9e-24 86.5 4.7 2.8 3 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding LEM PF03020.15 KIK52336.1 - 0.041 13.4 0.3 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 LEM domain Fez1 PF06818.15 KIK52336.1 - 1.5 9.3 17.8 1.2 9.6 2.6 2.5 2 0 0 2 2 2 0 Fez1 DUF4407 PF14362.6 KIK52336.1 - 2.8 7.2 15.1 0.65 9.3 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4758 PF15950.5 KIK52336.1 - 7.9 6.8 9.6 2.2 8.6 0.5 3.1 2 0 0 2 2 2 0 Putative sperm flagellar membrane protein DUF2235 PF09994.9 KIK52337.1 - 2.3e-96 322.5 0.0 2.9e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KIK52337.1 - 0.18 11.7 0.0 0.62 9.9 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FAD_binding_3 PF01494.19 KIK52338.1 - 7.6e-88 295.1 0.1 2e-87 293.7 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIK52338.1 - 2.8e-32 112.0 0.0 5.7e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KIK52338.1 - 3.3e-07 29.7 1.4 5.5e-07 29.0 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK52338.1 - 5.5e-07 28.6 0.9 1.1e-06 27.6 0.9 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KIK52338.1 - 1e-06 28.6 0.2 6.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK52338.1 - 1.3e-06 28.5 0.5 4.8e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIK52338.1 - 1.4e-06 27.9 0.1 2.3e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK52338.1 - 1.8e-06 27.4 1.0 4.8e-06 26.0 0.6 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK52338.1 - 1.2e-05 24.5 0.8 1.9e-05 23.9 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KIK52338.1 - 1.7e-05 24.2 0.1 3.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KIK52338.1 - 3.3e-05 22.9 0.3 6e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KIK52338.1 - 9.9e-05 22.8 0.6 0.0039 17.7 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIK52338.1 - 0.00032 20.1 0.3 0.00054 19.3 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIK52338.1 - 0.00088 18.6 0.7 0.0016 17.8 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK52338.1 - 0.001 18.2 2.0 0.0062 15.6 1.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK52338.1 - 0.0016 18.5 0.3 0.075 13.0 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KIK52338.1 - 0.017 15.6 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KIK52338.1 - 0.023 14.3 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIK52338.1 - 0.023 14.2 0.2 0.04 13.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIK52338.1 - 0.027 14.4 0.3 0.046 13.6 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIK52338.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 ThiF family DNA_pol_delta_4 PF04081.13 KIK52340.1 - 1.1e-29 103.5 0.1 1.2e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Pneumo_ncap PF03246.13 KIK52340.1 - 0.089 11.5 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein DUF4665 PF15679.5 KIK52340.1 - 0.12 13.0 0.1 0.16 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) F-box PF00646.33 KIK52341.1 - 1e-05 25.2 0.0 3.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK52341.1 - 3.1e-05 23.8 0.2 8.4e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like Abhydrolase_3 PF07859.13 KIK52342.1 - 3.5e-46 157.7 0.0 5e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK52342.1 - 0.0018 17.2 0.1 0.0032 16.4 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KIK52342.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase RPAP1_N PF08621.10 KIK52346.1 - 0.0091 15.8 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal adh_short PF00106.25 KIK52348.1 - 4e-14 52.5 0.0 6.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK52348.1 - 1.1e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK52348.1 - 1.7e-08 34.6 0.0 5e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK52348.1 - 0.0072 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain WLM PF08325.10 KIK52349.1 - 8.5e-42 143.4 0.4 8.5e-42 143.4 0.4 2.2 1 1 1 2 2 2 1 WLM domain ubiquitin PF00240.23 KIK52349.1 - 3.4e-09 36.3 0.1 7.5e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIK52349.1 - 0.001 19.5 0.1 0.0023 18.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK52349.1 - 0.025 14.5 0.1 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain SVIP PF15811.5 KIK52349.1 - 0.072 13.6 1.5 0.072 13.6 1.5 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Zincin_1 PF06262.11 KIK52349.1 - 0.12 12.5 0.2 1.7 8.8 0.1 2.6 2 1 1 3 3 3 0 Zincin-like metallopeptidase adh_short PF00106.25 KIK52350.1 - 6.5e-13 48.6 0.1 1e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK52350.1 - 1.1e-09 38.2 0.1 1.7e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK52350.1 - 3.2e-07 30.4 0.0 5.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK52350.1 - 0.0019 18.5 0.2 0.0066 16.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NACHT PF05729.12 KIK52354.1 - 1.8e-13 50.8 0.1 3.1e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK52354.1 - 1.6e-06 28.6 0.0 3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK52354.1 - 0.00036 20.9 0.0 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KIK52354.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KIK52354.1 - 0.0019 18.2 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK52354.1 - 0.0051 17.1 0.0 0.016 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIK52354.1 - 0.0051 17.2 0.1 0.023 15.1 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK52354.1 - 0.013 16.1 0.0 0.035 14.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK52354.1 - 0.015 14.5 0.4 0.74 9.0 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.17 KIK52354.1 - 0.035 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KIK52354.1 - 0.037 13.7 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase APS_kinase PF01583.20 KIK52354.1 - 0.049 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Rad17 PF03215.15 KIK52354.1 - 0.05 13.5 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KIK52354.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KIK52354.1 - 0.095 12.8 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KIK52354.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK52354.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.13 KIK52356.1 - 0.0044 15.2 0.8 0.0062 14.7 0.8 1.1 1 0 0 1 1 1 1 DNA polymerase phi CENP-B_dimeris PF09026.10 KIK52356.1 - 0.018 15.5 9.3 0.047 14.1 9.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KIK52356.1 - 3.4 6.7 6.9 5.2 6.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KIK52356.1 - 4.5 6.5 6.1 7.7 5.7 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein Peptidase_C14 PF00656.22 KIK52357.1 - 1.1e-17 64.8 0.0 1.2e-17 64.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain RNA_pol_Rpb1_2 PF00623.20 KIK52357.1 - 0.015 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 DUF2235 PF09994.9 KIK52358.1 - 6.7e-77 258.7 0.2 7.9e-77 258.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK52363.1 - 1.1e-62 212.0 0.7 1.3e-62 211.8 0.7 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4375 PF14300.6 KIK52363.1 - 0.087 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DNA_pol_phi PF04931.13 KIK52367.1 - 0.0076 14.4 0.9 0.011 13.9 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi CENP-B_dimeris PF09026.10 KIK52367.1 - 0.039 14.3 11.0 0.092 13.1 11.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KIK52367.1 - 1.4 8.0 6.7 2.2 7.3 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Herpes_LMP1 PF05297.11 KIK52367.1 - 1.9 7.6 5.0 3.5 6.7 5.0 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NOA36 PF06524.12 KIK52367.1 - 7.2 5.8 5.3 12 5.1 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3866 PF12982.7 KIK52369.1 - 0.026 13.7 0.1 0.031 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Peptidase_M99_m PF17130.4 KIK52369.1 - 0.056 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 EF_assoc_2 PF08356.12 KIK52370.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 EF hand associated GPHR_N PF12537.8 KIK52370.1 - 0.12 12.5 0.5 0.16 12.1 0.4 1.4 1 1 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PsbN PF02468.15 KIK52370.1 - 0.5 10.2 2.5 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF456 PF04306.13 KIK52375.1 - 0.021 15.1 0.3 0.04 14.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Herpes_gE PF02480.16 KIK52375.1 - 0.029 13.1 0.1 0.043 12.6 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTP_tm PF18861.1 KIK52375.1 - 0.13 12.2 0.0 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2207 PF09972.9 KIK52375.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PMP1_2 PF08114.11 KIK52375.1 - 0.18 11.6 1.2 17 5.2 0.2 2.4 2 0 0 2 2 2 0 ATPase proteolipid family KleE PF17394.2 KIK52376.1 - 0.051 13.8 1.9 0.089 13.0 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein Cyt_c_ox_IV PF12270.8 KIK52378.1 - 0.0016 18.5 0.7 0.055 13.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome c oxidase subunit IV RIFIN PF02009.16 KIK52379.1 - 0.00047 20.1 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 Rifin Protocadherin PF08374.11 KIK52379.1 - 0.0063 16.5 0.1 0.0086 16.1 0.1 1.1 1 0 0 1 1 1 1 Protocadherin Nitrate_red_gam PF02665.14 KIK52379.1 - 0.0084 15.7 0.4 0.014 14.9 0.4 1.3 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Miga PF10265.9 KIK52379.1 - 0.01 14.8 0.7 0.014 14.4 0.7 1.1 1 0 0 1 1 1 0 Mitoguardin EphA2_TM PF14575.6 KIK52379.1 - 0.018 15.9 0.0 0.029 15.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KIK52379.1 - 0.095 12.5 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KIK52379.1 - 0.12 12.3 1.1 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 KIK52379.1 - 0.27 11.3 0.8 0.5 10.5 0.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Abhydrolase_6 PF12697.7 KIK52380.1 - 3.3e-11 44.2 0.0 4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK52380.1 - 0.00063 19.5 0.1 0.00094 18.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold SPX PF03105.19 KIK52382.1 - 6e-35 121.9 1.5 1.1e-34 121.1 1.0 1.7 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 KIK52382.1 - 1.5e-07 31.2 7.6 2.4e-07 30.5 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK52382.1 - 1.8e-07 30.9 6.8 2.7e-07 30.3 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK52382.1 - 5.8e-07 29.6 6.5 1e-06 28.8 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK52382.1 - 2.4e-06 27.8 8.3 3.8e-06 27.1 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK52382.1 - 1.6e-05 24.7 6.4 2.7e-05 23.9 6.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK52382.1 - 0.00013 21.9 5.7 0.00026 20.9 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK52382.1 - 0.00024 21.0 7.6 0.00044 20.1 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK52382.1 - 0.001 18.9 8.3 0.0016 18.2 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KIK52382.1 - 0.0028 17.4 5.2 0.0052 16.5 5.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KIK52382.1 - 0.0067 16.3 3.7 0.012 15.4 3.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIK52382.1 - 0.013 15.7 4.8 0.028 14.7 4.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KIK52382.1 - 0.047 13.8 4.1 0.085 13.0 4.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KIK52382.1 - 0.096 12.7 1.9 0.19 11.8 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CdiI PF07262.11 KIK52382.1 - 0.11 12.2 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 CDI immunity protein NACHT PF05729.12 KIK52383.1 - 6.5e-15 55.4 0.1 1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK52383.1 - 5.1e-07 30.2 0.1 9.5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK52383.1 - 4.1e-05 23.6 0.0 7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK52383.1 - 0.00014 22.3 0.0 0.00061 20.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK52383.1 - 0.00049 20.5 0.0 0.0029 18.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KIK52383.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK52383.1 - 0.0027 17.7 0.0 0.55 10.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIK52383.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK52383.1 - 0.017 14.9 0.1 0.058 13.1 0.0 1.9 3 0 0 3 3 3 0 Cytidylate kinase Parvo_NS1 PF01057.17 KIK52383.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KIK52383.1 - 0.041 14.4 0.0 0.082 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK52383.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 KIK52383.1 - 0.058 12.6 0.4 1.8 7.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KIK52383.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK52383.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Fic_N PF13784.6 KIK52383.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Fic/DOC family N-terminal Orthopox_A5L PF06193.11 KIK52383.1 - 0.13 11.6 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like AAA_7 PF12775.7 KIK52383.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KIK52383.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SPX PF03105.19 KIK52384.1 - 7.1e-05 22.9 0.3 0.00041 20.4 0.3 1.9 1 1 0 1 1 1 1 SPX domain Glyco_hydro_31 PF01055.26 KIK52385.1 - 1.6e-84 284.7 0.1 1.1e-82 278.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Phage_1_1 PF08200.11 KIK52388.1 - 0.12 12.8 1.4 0.32 11.5 1.4 1.6 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein Gal_mutarotas_2 PF13802.6 KIK52389.1 - 3.5e-08 33.6 0.7 9.6e-05 22.6 0.1 2.6 2 1 1 3 3 3 2 Galactose mutarotase-like NtCtMGAM_N PF16863.5 KIK52389.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 2 0 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DEAD PF00270.29 KIK52390.1 - 8.2e-05 22.4 0.0 0.00025 20.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2235 PF09994.9 KIK52391.1 - 1.8e-61 208.1 0.0 2.2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK52392.1 - 3.6e-71 239.9 0.0 4.4e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Retrotran_gag_2 PF14223.6 KIK52396.1 - 6.3e-08 32.4 0.2 8.8e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DEC-1_N PF04625.13 KIK52396.1 - 0.042 12.9 0.2 0.048 12.7 0.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Extensin_2 PF04554.13 KIK52397.1 - 0.052 13.6 3.7 0.052 13.6 3.7 3.2 3 0 0 3 3 3 0 Extensin-like region Aldo_ket_red PF00248.21 KIK52398.1 - 1.2e-08 34.5 0.0 1.4e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SPX PF03105.19 KIK52399.1 - 2.4 8.0 5.8 3.2 7.6 5.8 1.2 1 0 0 1 1 1 0 SPX domain DUF1154 PF06631.11 KIK52400.1 - 0.43 10.6 11.3 0.16 12.0 6.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) aGPT-Pplase1 PF18723.1 KIK52401.1 - 0.0019 17.7 0.1 0.0045 16.5 0.1 1.6 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 SopA PF13981.6 KIK52401.1 - 0.19 12.2 0.1 1.5 9.2 0.0 2.6 3 0 0 3 3 3 0 SopA-like central domain OrsD PF12013.8 KIK52403.1 - 0.02 15.4 0.0 0.08 13.4 0.0 2.1 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D EccE PF11203.8 KIK52403.1 - 0.1 12.9 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE GPI-anchored PF10342.9 KIK52406.1 - 0.00013 22.7 0.0 0.00098 19.8 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_S8 PF00410.19 KIK52408.1 - 0.061 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S8 AAA_12 PF13087.6 KIK52409.1 - 7.2e-21 74.7 0.1 8.6e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK52409.1 - 0.00066 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIK52409.1 - 0.085 12.6 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIK52410.1 - 4.2e-05 23.3 0.0 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK52410.1 - 6.6e-05 22.8 0.1 0.12 12.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK52410.1 - 0.058 13.7 0.1 0.15 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_12 PF13087.6 KIK52413.1 - 6.4e-25 88.0 0.0 8.7e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK52413.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KIK52414.1 - 2.7e-17 63.4 0.6 2.6e-08 34.0 0.1 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KIK52414.1 - 2.4e-12 47.0 0.0 8.4e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK52414.1 - 1.2e-11 45.1 0.0 3.3e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK52414.1 - 4e-05 24.1 0.0 9.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK52414.1 - 0.0008 19.8 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KIK52414.1 - 0.0067 16.2 0.1 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KIK52414.1 - 0.026 14.8 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KIK52414.1 - 0.032 13.7 0.1 0.063 12.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KIK52414.1 - 0.034 13.4 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Hydin_ADK PF17213.3 KIK52414.1 - 0.044 14.1 1.1 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 KIK52414.1 - 0.086 12.3 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 KIK52414.1 - 0.12 12.2 0.2 0.66 9.8 0.0 2.2 2 1 0 2 2 2 0 Helicase AAA_11 PF13086.6 KIK52416.1 - 1.4e-12 48.0 0.0 3.3e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK52416.1 - 3.1e-11 43.4 0.0 8.1e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK52416.1 - 1e-09 38.9 0.0 1.6e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK52416.1 - 8.9e-06 26.2 0.0 9.2e-06 26.1 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK52416.1 - 0.00013 22.4 0.3 0.00032 21.1 0.2 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 KIK52416.1 - 0.0018 18.2 0.0 0.0076 16.1 0.0 1.8 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.6 KIK52416.1 - 0.0025 18.1 0.6 0.0061 16.8 0.6 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KIK52416.1 - 0.0048 16.5 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KIK52416.1 - 0.0073 15.5 0.2 0.012 14.8 0.2 1.4 1 1 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KIK52416.1 - 0.0074 15.6 0.0 0.0074 15.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KIK52416.1 - 0.0074 16.4 0.2 0.0096 16.1 0.2 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK52416.1 - 0.011 15.7 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KIK52416.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK52416.1 - 0.015 15.7 0.1 0.022 15.2 0.1 1.5 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK52416.1 - 0.033 14.7 0.1 0.047 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK52416.1 - 0.033 14.4 0.3 0.066 13.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIK52416.1 - 0.04 13.7 0.5 0.1 12.3 0.2 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KIK52416.1 - 0.049 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIK52416.1 - 0.056 13.4 0.1 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KIK52416.1 - 0.063 13.2 0.5 0.11 12.4 0.4 1.7 1 1 0 1 1 1 0 NTPase Rad17 PF03215.15 KIK52416.1 - 0.071 13.0 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 KIK52416.1 - 0.093 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 KIK52416.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.21 KIK52416.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 KIK52416.1 - 0.11 12.2 0.4 0.41 10.4 0.4 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase cobW PF02492.19 KIK52416.1 - 0.14 11.8 0.2 0.26 10.9 0.1 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF5510 PF17629.2 KIK52417.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5510) AAA_30 PF13604.6 KIK52418.1 - 2.7e-14 53.3 0.0 1.9e-13 50.5 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KIK52418.1 - 8.1e-14 52.0 0.0 1.6e-07 31.4 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK52418.1 - 4.3e-10 40.1 0.0 1.4e-09 38.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK52418.1 - 0.0001 22.8 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK52418.1 - 0.00096 19.6 0.0 0.0023 18.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK52418.1 - 0.0035 17.6 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIK52418.1 - 0.018 14.8 0.2 0.5 10.1 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KIK52418.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 KIK52418.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 KIK52418.1 - 0.056 13.6 0.1 0.18 12.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK52418.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK52418.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain XRN1_D1 PF18332.1 KIK52419.1 - 2.7e-68 229.5 0.0 4.1e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KIK52419.1 - 2.9e-28 97.9 1.4 3.4e-28 97.7 0.3 1.7 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KIK52419.1 - 9.3e-24 83.3 0.1 2.7e-23 81.8 0.1 1.9 2 0 0 2 2 2 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KIK52419.1 - 6.3e-09 35.8 0.4 1.3e-08 34.8 0.1 1.7 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 Rad54_N PF08658.10 KIK52421.1 - 0.11 12.6 1.8 0.2 11.8 1.8 1.3 1 0 0 1 1 1 0 Rad54 N terminal Lipase_GDSL_2 PF13472.6 KIK52422.1 - 0.00016 22.1 0.1 0.00023 21.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK52422.1 - 0.0041 17.1 0.0 0.0063 16.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SWIM PF04434.17 KIK52423.1 - 0.0047 16.6 1.3 0.0071 16.0 1.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger Med1 PF10744.9 KIK52424.1 - 0.089 11.8 0.0 0.098 11.7 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Lipocalin_5 PF13924.6 KIK52425.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Lipocalin-like domain Peroxidase_ext PF11895.8 KIK52427.1 - 1.9e-28 98.2 4.2 2.4e-28 97.9 2.0 2.3 3 0 0 3 3 3 1 Fungal peroxidase extension region peroxidase PF00141.23 KIK52427.1 - 3.2e-23 82.6 0.0 5.9e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Peroxidase IDO PF01231.18 KIK52428.1 - 4e-133 444.4 0.0 4.5e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AA_permease_2 PF13520.6 KIK52429.1 - 9.3e-54 182.9 48.4 1.2e-53 182.5 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK52429.1 - 1.3e-16 60.3 38.3 1.8e-16 59.8 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease 2TM PF13239.6 KIK52429.1 - 0.19 12.0 0.2 0.19 12.0 0.2 4.1 4 2 1 5 5 5 0 2TM domain F-box-like PF12937.7 KIK52430.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK52432.1 - 0.006 16.5 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.7 KIK52432.1 - 0.035 14.0 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIK52433.1 - 0.0017 18.2 0.3 0.0071 16.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK52434.1 - 0.00057 19.7 0.0 0.0019 18.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK52434.1 - 0.063 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain La PF05383.17 KIK52435.1 - 4.9e-22 77.7 0.1 9.4e-22 76.8 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KIK52435.1 - 1.1e-08 34.7 0.0 3.9e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK52435.1 - 7.8e-07 29.1 0.2 2.2e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 RNA binding motif VTC PF09359.10 KIK52436.1 - 0.05 13.0 0.0 0.053 12.9 0.0 1.0 1 0 0 1 1 1 0 VTC domain Glyco_hydro_18 PF00704.28 KIK52437.1 - 1e-11 45.1 0.3 1.2e-11 44.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FoP_duplication PF13865.6 KIK52438.1 - 1.4 9.6 16.8 1.7 9.3 16.8 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 La PF05383.17 KIK52440.1 - 2.2e-07 30.8 0.1 4.1e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KIK52440.1 - 1.4e-06 28.0 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TraI PF07057.11 KIK52440.1 - 0.13 12.4 0.1 0.69 10.1 0.0 1.9 1 1 1 2 2 2 0 DNA helicase TraI Dyp_perox PF04261.12 KIK52441.1 - 1.8e-06 27.2 0.4 0.029 13.3 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family Amino_oxidase PF01593.24 KIK52442.1 - 4.4e-44 151.5 0.1 6.9e-44 150.9 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK52442.1 - 2.2e-10 40.6 0.0 4.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK52442.1 - 0.0023 17.2 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK52442.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIK52442.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIK52442.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK52442.1 - 0.1 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like EAGR_box PF16713.5 KIK52443.1 - 0.024 14.3 0.5 0.057 13.1 0.5 1.5 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box Inhibitor_I66 PF16850.5 KIK52445.1 - 6.2e-07 29.4 0.0 8.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 Dyp_perox PF04261.12 KIK52446.1 - 0.00075 18.6 0.1 0.023 13.7 0.0 2.5 3 0 0 3 3 3 2 Dyp-type peroxidase family Amino_oxidase PF01593.24 KIK52447.1 - 1.4e-36 126.7 0.3 7.5e-36 124.4 0.3 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK52447.1 - 0.0073 16.5 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain EAGR_box PF16713.5 KIK52448.1 - 0.0045 16.6 0.7 0.023 14.4 0.5 1.9 2 0 0 2 2 2 1 Enriched in aromatic and glycine Residues box NRN1 PF15056.6 KIK52449.1 - 0.04 14.0 2.0 0.94 9.6 0.1 2.2 1 1 1 2 2 2 0 Neuritin protein family REPA_OB_2 PF16900.5 KIK52449.1 - 0.069 13.1 0.3 0.11 12.4 0.3 1.5 1 1 0 1 1 1 0 Replication protein A OB domain ApbA PF02558.16 KIK52450.1 - 0.0032 17.1 0.1 0.0048 16.5 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ATG13 PF10033.9 KIK52451.1 - 1.6e-21 77.1 0.0 2.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Glyco_hydro_31 PF01055.26 KIK52452.1 - 5.4e-100 335.6 0.0 1.8e-97 327.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK52452.1 - 3.4e-16 59.5 0.1 6e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK52452.1 - 1.4e-12 47.8 0.5 7.5e-12 45.4 0.5 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Ribonuc_red_sm PF00268.21 KIK52453.1 - 7.8e-24 84.6 0.0 1.8e-23 83.4 0.0 1.5 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain DUF3836 PF12930.7 KIK52454.1 - 0.15 11.8 0.3 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF3836) 2OG-FeII_Oxy_3 PF13640.6 KIK52455.1 - 0.04 14.8 0.0 0.093 13.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Spem1 PF15670.5 KIK52455.1 - 0.15 11.6 7.6 5.4 6.5 0.1 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 DMAP_binding PF06464.11 KIK52455.1 - 0.47 11.3 10.0 9.6 7.1 10.0 2.5 1 1 0 1 1 1 0 DMAP1-binding Domain Sina PF03145.16 KIK52456.1 - 0.0025 17.8 0.1 0.0041 17.1 0.1 1.2 1 0 0 1 1 1 1 Seven in absentia protein family OrsD PF12013.8 KIK52457.1 - 4.2e-09 36.9 0.1 1e-08 35.6 0.1 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-UBP PF02148.19 KIK52457.1 - 0.058 13.7 0.7 9.4 6.7 0.2 2.4 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DEAD PF00270.29 KIK52458.1 - 1.1e-07 31.8 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK52458.1 - 1.4e-06 28.6 0.0 3.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_31 PF01055.26 KIK52459.1 - 8.1e-34 117.5 0.0 9.6e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 HD PF01966.22 KIK52460.1 - 3e-06 27.5 0.0 4.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KIK52460.1 - 3.8e-05 23.3 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 HDOD domain MIOX PF05153.15 KIK52460.1 - 0.00026 20.6 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD_4 PF13328.6 KIK52460.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 HD domain GYF PF02213.16 KIK52460.1 - 0.21 11.3 0.1 0.43 10.3 0.1 1.5 1 0 0 1 1 1 0 GYF domain HsbA PF12296.8 KIK52461.1 - 1.1e-18 67.7 11.1 1.1e-18 67.7 11.1 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A HsbA PF12296.8 KIK52463.1 - 1.2e-17 64.5 6.9 1.2e-17 64.5 6.9 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A AMP-binding PF00501.28 KIK52464.1 - 2e-23 82.7 0.0 7.2e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KIK52464.1 - 0.0086 15.0 0.0 0.033 13.1 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter BH3 PF15285.6 KIK52467.1 - 0.042 13.6 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting OATP PF03137.20 KIK52467.1 - 0.057 11.7 0.1 0.067 11.5 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UQ_con PF00179.26 KIK52469.1 - 3.9e-11 42.7 0.1 9.1e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme HIRAN PF08797.11 KIK52470.1 - 0.16 11.9 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 HIRAN domain Coat_X PF07552.11 KIK52471.1 - 0.14 12.0 1.9 0.22 11.4 1.8 1.4 1 1 0 1 1 1 0 Spore Coat Protein X and V domain TMEM154 PF15102.6 KIK52472.1 - 0.013 15.4 1.7 0.042 13.7 1.7 2.0 1 1 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 KIK52472.1 - 0.019 14.9 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 KIK52473.1 - 2.1e-07 30.9 1.6 2.1e-07 30.9 1.6 1.8 2 0 0 2 2 2 1 TMEM154 protein family EVI2A PF05399.11 KIK52473.1 - 0.00012 21.7 0.3 0.00012 21.7 0.3 1.6 2 0 0 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) Amnionless PF14828.6 KIK52473.1 - 0.00027 19.9 0.1 0.00038 19.4 0.1 1.3 1 0 0 1 1 1 1 Amnionless RIFIN PF02009.16 KIK52473.1 - 0.00057 19.9 0.0 0.00067 19.7 0.0 1.2 1 0 0 1 1 1 1 Rifin Stevor PF17410.2 KIK52473.1 - 0.0012 18.5 0.2 0.002 17.7 0.2 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 KIK52473.1 - 0.0067 16.7 3.3 0.0068 16.7 0.9 2.3 2 1 0 2 2 2 1 Orf78 (ac78) EphA2_TM PF14575.6 KIK52473.1 - 0.011 16.6 0.9 0.034 15.0 0.0 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 KIK52473.1 - 0.016 15.6 6.2 0.016 15.6 6.2 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KIK52473.1 - 0.017 14.5 1.2 0.034 13.5 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PAP2_3 PF14378.6 KIK52473.1 - 0.022 14.5 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily DUF4690 PF15756.5 KIK52473.1 - 0.026 15.1 1.7 0.026 15.1 1.7 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF2207 PF09972.9 KIK52473.1 - 0.1 11.3 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPX PF03105.19 KIK52473.1 - 0.11 12.4 7.2 0.13 12.2 7.2 1.3 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 KIK52473.1 - 0.14 12.6 8.9 0.42 11.0 8.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) FixQ PF05545.11 KIK52473.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Macoilin PF09726.9 KIK52473.1 - 0.36 9.3 3.8 0.36 9.3 3.8 1.1 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 KIK52473.1 - 0.73 9.2 4.1 1.3 8.4 4.1 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Glypican PF01153.19 KIK52473.1 - 8.2 5.1 6.4 11 4.7 6.4 1.1 1 0 0 1 1 1 0 Glypican GRP PF07172.11 KIK52473.1 - 8.5 7.1 20.5 1.5e+02 3.1 18.6 2.9 2 1 0 2 2 2 0 Glycine rich protein family AAA_16 PF13191.6 KIK52474.1 - 1.9e-10 41.4 0.1 1.1e-09 38.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK52474.1 - 6e-08 32.8 0.1 1.6e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK52474.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 KIK52474.1 - 0.0016 18.4 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 KIK52474.1 - 0.0024 16.9 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KIK52474.1 - 0.0036 17.2 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIK52474.1 - 0.0046 16.7 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK52474.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase CbiA PF01656.23 KIK52474.1 - 0.016 15.3 0.1 0.056 13.5 0.1 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KIK52474.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK52474.1 - 0.12 13.0 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KIK52474.1 - 0.13 11.4 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KIK52474.1 - 0.14 11.9 0.2 0.43 10.4 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 KIK52474.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3902 PF13042.6 KIK52475.1 - 0.33 10.5 5.0 0.21 11.2 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3902) Hydrophobin PF01185.18 KIK52477.1 - 2.4e-22 79.3 10.3 3.4e-22 78.9 10.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Cys_Knot_tox PF17486.2 KIK52477.1 - 0.18 12.1 4.1 2 8.7 0.3 2.2 2 0 0 2 2 2 0 Cystine knot toxins Peptidase_M28 PF04389.17 KIK52479.1 - 6.7e-21 74.9 0.0 9.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK52479.1 - 6.5e-08 32.5 0.1 1.4e-07 31.4 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PTR2 PF00854.21 KIK52480.1 - 1.1e-79 268.2 10.7 1.4e-79 267.8 10.7 1.1 1 0 0 1 1 1 1 POT family PalH PF08733.10 KIK52480.1 - 0.37 9.8 9.8 0.26 10.2 1.5 2.2 2 0 0 2 2 2 0 PalH/RIM21 Asp PF00026.23 KIK52481.1 - 7.6e-82 275.2 12.1 9e-82 275.0 12.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK52481.1 - 1.1e-12 48.6 11.0 2.2e-11 44.3 11.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK52481.1 - 0.016 15.0 0.2 0.11 12.3 0.2 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal TMEM171 PF15471.6 KIK52482.1 - 0.069 12.1 1.2 0.079 11.9 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 GMC_oxred_N PF00732.19 KIK52485.1 - 2.5e-62 210.9 0.0 3.2e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK52485.1 - 2.9e-33 115.4 0.0 4.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK52485.1 - 0.0074 15.4 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK52485.1 - 0.011 15.4 0.1 0.03 13.9 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK52485.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK52485.1 - 0.019 15.2 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK52485.1 - 0.056 12.7 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK52485.1 - 0.072 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KIK52485.1 - 0.082 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Peptidase_M28 PF04389.17 KIK52487.1 - 3.5e-21 75.8 0.0 7.7e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK52487.1 - 1.2e-06 28.3 0.0 3.1e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Lyase_aromatic PF00221.19 KIK52488.1 - 4.8e-130 434.3 0.9 5.9e-130 434.0 0.9 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Lyase_aromatic PF00221.19 KIK52489.1 - 1.2e-128 429.8 0.5 1.4e-128 429.5 0.5 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Cu_bind_like PF02298.17 KIK52491.1 - 0.0066 16.4 1.9 0.94 9.5 0.1 3.3 2 2 0 2 2 2 2 Plastocyanin-like domain adh_short PF00106.25 KIK52492.1 - 1.9e-25 89.5 0.0 2.6e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK52492.1 - 9.5e-17 61.3 0.0 1.3e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK52492.1 - 4.5e-11 43.0 0.0 6.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK52492.1 - 0.00016 20.9 0.0 0.00035 19.8 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK52492.1 - 0.05 13.1 0.1 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK52492.1 - 0.092 12.1 0.1 0.66 9.3 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK52493.1 - 4.3e-25 88.3 0.0 5.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK52493.1 - 1.6e-14 54.0 0.0 2.1e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK52493.1 - 2e-08 34.3 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK52493.1 - 0.0002 20.6 0.0 0.00062 19.0 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein tRNA-synt_His PF13393.6 KIK52493.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-H2C2_5 PF13909.6 KIK52494.1 - 0.00048 19.8 5.1 0.0083 15.9 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK52494.1 - 0.0012 19.1 0.7 0.0012 19.1 0.7 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK52494.1 - 0.014 15.8 1.2 0.014 15.8 1.2 3.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK52494.1 - 0.017 15.9 7.6 0.3 12.0 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0561 PF10573.9 KIK52494.1 - 0.023 14.8 2.7 0.029 14.5 2.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 OrsD PF12013.8 KIK52494.1 - 0.1 13.1 3.3 0.5 10.8 0.1 2.2 1 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D IBR PF01485.21 KIK52494.1 - 0.41 10.9 5.8 0.41 10.9 4.3 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Dicty_REP PF05086.12 KIK52494.1 - 0.5 8.3 2.2 0.59 8.1 2.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5090 PF17009.5 KIK52495.1 - 1.5 8.8 6.3 0.39 10.7 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) A2M PF00207.22 KIK52497.1 - 0.028 14.2 0.1 0.078 12.8 0.1 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin family DUF5627 PF18620.1 KIK52497.1 - 0.64 9.9 4.0 0.32 10.9 1.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5627) Glyco_hydro_3_C PF01915.22 KIK52498.1 - 4.5e-33 114.9 0.2 2.2e-32 112.7 0.0 2.2 2 1 1 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIK52498.1 - 4.8e-17 61.8 0.8 9.2e-17 60.9 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KIK52498.1 - 3e-14 53.1 0.0 3.1e-13 49.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain DUF3149 PF11346.8 KIK52501.1 - 0.047 13.3 3.5 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF872 PF05915.12 KIK52501.1 - 0.17 12.1 0.5 0.28 11.3 0.5 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) CcmD PF04995.14 KIK52501.1 - 1.7 8.8 5.3 6.9 6.8 5.0 2.2 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4668 PF15701.5 KIK52503.1 - 0.23 11.3 1.7 0.3 10.9 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) DHHC PF01529.20 KIK52503.1 - 1.2 9.2 5.1 3 7.9 0.0 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase Arrestin_N PF00339.29 KIK52505.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIK52505.1 - 0.054 13.9 0.0 0.57 10.6 0.0 2.7 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Av_adeno_fibre PF06536.11 KIK52507.1 - 0.32 10.9 3.6 3.3 7.6 0.1 2.5 3 0 0 3 3 3 0 Avian adenovirus fibre, N-terminal Fez1 PF06818.15 KIK52508.1 - 0.026 15.0 5.2 0.041 14.3 5.2 1.2 1 0 0 1 1 1 0 Fez1 PKcGMP_CC PF16808.5 KIK52508.1 - 0.25 11.2 8.1 0.61 10.0 0.4 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK52508.1 - 0.33 11.3 10.9 0.12 12.7 3.8 2.5 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF641 PF04859.12 KIK52508.1 - 0.73 10.2 6.1 0.5 10.7 0.6 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KIK52509.1 - 0.011 14.6 2.6 0.017 14.0 2.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 KIK52509.1 - 0.066 12.9 3.0 2.6 7.7 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK52509.1 - 0.17 11.8 4.9 5.4 7.0 0.3 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KIK52509.1 - 6.4 7.5 8.1 14 6.4 1.1 3.2 1 1 2 3 3 3 0 SlyX Plavaka PF18759.1 KIK52510.1 - 1e-64 218.8 0.1 1.1e-64 218.7 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK52511.1 - 8e-15 54.9 0.1 1.1e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase CLLAC PF15675.5 KIK52511.1 - 0.079 12.5 0.1 0.079 12.5 0.1 1.8 2 0 0 2 2 2 0 CLLAC-motif containing domain GMC_oxred_N PF00732.19 KIK52514.1 - 1e-54 185.9 0.0 1.3e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK52514.1 - 8.8e-32 110.6 0.0 1.4e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KIK52514.1 - 0.003 16.8 0.9 0.0057 15.9 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK52514.1 - 0.0033 17.0 0.2 0.0067 16.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK52514.1 - 0.0056 15.8 3.5 0.052 12.6 3.2 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK52514.1 - 0.007 16.6 2.4 0.017 15.3 2.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK52514.1 - 0.011 14.8 0.6 0.016 14.3 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KIK52514.1 - 0.013 14.7 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIK52514.1 - 0.029 13.6 1.6 0.3 10.3 1.7 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KIK52515.1 - 3.5e-62 210.2 0.2 4e-62 210.1 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cpn60_TCP1 PF00118.24 KIK52517.1 - 2e-45 155.4 10.5 2e-24 86.1 0.4 3.0 2 1 1 3 3 3 3 TCP-1/cpn60 chaperonin family Plavaka PF18759.1 KIK52518.1 - 4.1e-77 259.6 0.1 3.9e-74 249.8 0.1 2.2 1 1 0 1 1 1 1 Plavaka transposase Sec2p PF06428.11 KIK52519.1 - 0.005 16.8 2.2 0.005 16.8 2.2 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Fez1 PF06818.15 KIK52519.1 - 0.0082 16.6 6.0 0.014 15.9 6.0 1.2 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KIK52519.1 - 0.018 13.9 9.8 0.029 13.3 9.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KIK52519.1 - 0.024 14.5 10.7 0.94 9.4 0.3 3.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1635 PF07795.11 KIK52519.1 - 0.042 13.7 3.4 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) AAA_13 PF13166.6 KIK52519.1 - 0.053 12.2 2.9 0.074 11.7 2.9 1.1 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 KIK52519.1 - 0.053 13.9 9.7 0.13 12.6 2.1 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain LRS4 PF10422.9 KIK52519.1 - 0.091 12.3 6.1 0.15 11.6 6.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF641 PF04859.12 KIK52519.1 - 0.19 12.0 6.8 0.67 10.3 0.5 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) HMMR_N PF15905.5 KIK52519.1 - 0.2 11.1 9.6 0.11 11.9 7.7 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 KIK52519.1 - 0.22 11.6 11.2 0.52 10.3 3.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CC2-LZ PF16516.5 KIK52519.1 - 0.3 11.5 10.6 0.73 10.2 1.9 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KASH_CCD PF14662.6 KIK52519.1 - 0.3 10.9 11.1 1.1 9.1 11.1 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 KIK52519.1 - 0.3 11.2 3.8 1.3 9.2 3.8 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KIK52519.1 - 0.56 10.3 9.0 0.31 11.1 4.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KIK52519.1 - 0.59 9.9 6.7 1 9.1 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 KIK52519.1 - 0.64 9.7 9.3 4.6 6.9 7.8 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Cnn_1N PF07989.11 KIK52519.1 - 1.6 8.9 5.3 1.7 8.9 0.1 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Rho_Binding PF08912.11 KIK52519.1 - 2.4 9.1 7.3 2.1 9.2 0.8 2.4 2 0 0 2 2 2 0 Rho Binding DUF1664 PF07889.12 KIK52519.1 - 2.9 8.0 4.8 3.7 7.6 3.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KIK52519.1 - 4.8 7.3 11.5 58 3.8 11.4 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 KIK52519.1 - 4.9 7.0 7.8 3.8 7.3 0.4 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 FAS_N PF17828.1 KIK52520.1 - 0.031 14.3 0.3 0.062 13.3 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF648 PF04890.13 KIK52520.1 - 0.065 13.0 0.4 0.1 12.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) BCDHK_Adom3 PF10436.9 KIK52520.1 - 0.07 13.0 0.6 9.6 6.0 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HAD_SAK_1 PF10307.9 KIK52520.1 - 0.082 12.7 0.7 0.15 11.8 0.7 1.3 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins TED_complement PF07678.14 KIK52520.1 - 0.11 11.5 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF4939 PF16297.5 KIK52521.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) SWIB PF02201.18 KIK52521.1 - 0.057 13.3 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 SWIB/MDM2 domain p450 PF00067.22 KIK52522.1 - 5.3e-56 190.3 0.0 9.2e-42 143.4 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 UbiA PF01040.18 KIK52523.1 - 3.2e-23 82.3 21.3 5e-23 81.7 21.3 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KIK52524.1 - 1e-59 202.6 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK52525.1 - 6.9e-55 186.6 0.0 8.6e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S49_N PF08496.10 KIK52526.1 - 0.017 15.2 1.5 0.026 14.6 1.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM76 PF16046.5 KIK52526.1 - 0.045 13.1 1.2 0.062 12.6 1.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF3450 PF11932.8 KIK52526.1 - 0.15 11.3 7.5 0.26 10.6 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MscS_porin PF12795.7 KIK52526.1 - 0.2 11.1 12.9 0.24 10.9 11.4 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Sec2p PF06428.11 KIK52526.1 - 0.83 9.7 8.0 0.095 12.7 1.8 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4337 PF14235.6 KIK52526.1 - 1.5 8.9 3.2 2.4 8.3 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cnn_1N PF07989.11 KIK52526.1 - 4.6 7.5 7.9 8.2 6.7 2.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-CCHC PF00098.23 KIK52528.1 - 4.5e-05 23.3 3.8 8.2e-05 22.5 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle HET-S PF17108.5 KIK52529.1 - 0.4 10.5 5.0 11 5.9 0.4 2.6 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic gag-asp_proteas PF13975.6 KIK52530.1 - 9.1e-05 22.9 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK52530.1 - 0.0011 18.8 0.1 0.0015 18.3 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KIK52530.1 - 0.0024 18.5 0.0 0.0031 18.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease CENP-B_N PF04218.13 KIK52533.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Fer4_17 PF13534.6 KIK52533.1 - 0.029 14.9 2.3 0.055 14.0 0.5 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain MetallophosN PF16371.5 KIK52534.1 - 0.058 13.7 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase Dehydratase_SU PF02287.15 KIK52534.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Dehydratase small subunit DDE_3 PF13358.6 KIK52546.1 - 4.2e-06 26.6 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CxC2 PF18803.1 KIK52551.1 - 2.5e-24 85.5 0.3 2.9e-24 85.3 0.3 1.0 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases ChitinaseA_N PF08329.10 KIK52551.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain GxGYxYP_C PF14323.6 KIK52552.1 - 0.0088 15.9 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 GxGYxYP putative glycoside hydrolase C-terminal domain KDZ PF18758.1 KIK52553.1 - 2.6e-16 59.9 0.6 2.9e-16 59.8 0.6 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase bZIP_2 PF07716.15 KIK52555.1 - 0.23 11.6 2.7 0.77 9.9 2.7 1.9 1 0 0 1 1 1 0 Basic region leucine zipper GBR2_CC PF18455.1 KIK52556.1 - 0.039 14.1 0.1 0.097 12.8 0.1 1.6 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Csm1_N PF18504.1 KIK52556.1 - 0.048 14.0 1.4 0.078 13.3 0.3 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain VGPC1_C PF16799.5 KIK52556.1 - 0.067 13.2 1.2 0.35 10.9 0.1 2.6 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HMMR_C PF15908.5 KIK52556.1 - 0.088 13.1 0.4 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal FAM184 PF15665.5 KIK52556.1 - 0.11 12.2 1.4 0.2 11.4 1.4 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B JIP_LZII PF16471.5 KIK52556.1 - 0.41 10.9 3.5 0.41 10.8 0.8 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GIT_CC PF16559.5 KIK52556.1 - 1.8 8.5 6.3 9.4 6.2 0.7 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Totivirus_coat PF05518.11 KIK52557.1 - 5.2 5.0 8.8 7.6 4.5 8.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein DUF3915 PF13054.6 KIK52559.1 - 0.0093 15.9 0.6 0.033 14.2 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) IMUP PF15761.5 KIK52559.1 - 0.12 13.1 8.6 0.29 11.8 8.6 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein KDZ PF18758.1 KIK52560.1 - 4.8e-17 62.3 0.7 5e-17 62.3 0.7 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MFS_1 PF07690.16 KIK52563.1 - 2.1e-15 56.5 73.4 9.9e-15 54.3 43.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KIK52564.1 - 3.3e-09 37.6 0.0 6.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK52564.1 - 0.021 14.9 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain KDZ PF18758.1 KIK52566.1 - 2.4e-17 63.3 0.4 7.7e-17 61.6 0.1 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase fragilysinNterm PF16376.5 KIK52566.1 - 0.085 12.6 0.4 0.15 11.8 0.4 1.3 1 0 0 1 1 1 0 N-terminal domain of fragilysin HVSL PF09749.9 KIK52567.1 - 0.035 13.6 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein Cdh1_DBD_1 PF18196.1 KIK52568.1 - 0.068 13.5 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Thioredoxin_2 PF13098.6 KIK52568.1 - 0.083 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3492 PF11997.8 KIK52568.1 - 0.29 10.8 1.6 3.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Spc7 PF08317.11 KIK52570.1 - 9.4e-05 21.4 3.9 0.0001 21.3 3.9 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein HMMR_N PF15905.5 KIK52570.1 - 0.00031 20.3 2.7 0.00042 19.9 2.7 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Sec2p PF06428.11 KIK52570.1 - 0.0005 20.0 1.2 0.0005 20.0 1.2 2.1 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 KIK52570.1 - 0.00061 20.0 1.1 0.00096 19.4 1.1 1.4 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KIK52570.1 - 0.00062 20.0 9.2 0.018 15.3 1.6 2.7 2 1 0 2 2 2 2 Csm1 N-terminal domain FAM76 PF16046.5 KIK52570.1 - 0.00079 18.9 2.1 0.00097 18.6 2.1 1.1 1 0 0 1 1 1 1 FAM76 protein YscO-like PF16789.5 KIK52570.1 - 0.0025 17.8 2.6 0.0031 17.6 2.6 1.0 1 0 0 1 1 1 1 YscO-like protein Fungal_TACC PF12709.7 KIK52570.1 - 0.0035 17.8 2.7 0.45 11.0 0.0 2.1 2 0 0 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 KIK52570.1 - 0.0039 17.3 3.2 0.22 11.7 0.6 2.1 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 LRS4 PF10422.9 KIK52570.1 - 0.0062 16.1 4.4 0.0067 16.0 4.4 1.0 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 TMF_DNA_bd PF12329.8 KIK52570.1 - 0.0065 16.4 8.4 0.14 12.2 1.1 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KIK52570.1 - 0.0077 16.5 7.8 0.2 11.8 1.3 2.0 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KIK52570.1 - 0.012 15.4 5.2 0.015 15.2 5.2 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 KIK52570.1 - 0.014 15.1 3.5 0.032 14.0 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FliJ PF02050.16 KIK52570.1 - 0.015 15.5 2.1 0.17 12.1 0.3 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein ADIP PF11559.8 KIK52570.1 - 0.017 15.2 8.1 0.36 10.9 0.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KIK52570.1 - 0.023 15.3 1.4 2.3 8.9 0.2 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Peptidase_S49_N PF08496.10 KIK52570.1 - 0.023 14.7 0.4 0.041 13.9 0.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF3450 PF11932.8 KIK52570.1 - 0.027 13.8 1.5 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 KIK52570.1 - 0.032 14.3 6.9 0.79 9.9 1.5 2.6 2 1 0 2 2 2 0 bZIP transcription factor Med9 PF07544.13 KIK52570.1 - 0.036 14.2 3.3 3.3 7.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Bacillus_HBL PF05791.11 KIK52570.1 - 0.057 13.3 0.3 0.068 13.0 0.3 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CC2-LZ PF16516.5 KIK52570.1 - 0.059 13.7 6.3 1.5 9.3 1.1 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HemX PF04375.14 KIK52570.1 - 0.071 12.4 1.9 0.081 12.2 1.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase USP8_interact PF08941.10 KIK52570.1 - 0.073 12.9 1.0 0.79 9.5 0.7 1.9 1 1 1 2 2 2 0 USP8 interacting Phage_GP20 PF06810.11 KIK52570.1 - 0.079 12.8 5.7 0.19 11.5 0.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 PKcGMP_CC PF16808.5 KIK52570.1 - 0.085 12.7 6.6 2.8 7.9 0.4 2.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 KIK52570.1 - 0.086 12.9 1.2 0.17 11.9 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.6 KIK52570.1 - 0.096 12.0 7.6 0.89 8.9 0.9 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KIK52570.1 - 0.098 13.3 4.3 2 9.1 0.3 2.2 1 1 1 2 2 2 0 SlyX NPV_P10 PF05531.12 KIK52570.1 - 0.14 12.6 0.2 1.6 9.2 0.0 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MPS2 PF17060.5 KIK52570.1 - 0.15 11.3 4.1 0.11 11.8 0.5 1.8 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF641 PF04859.12 KIK52570.1 - 0.2 12.0 5.5 0.36 11.2 0.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.6 KIK52570.1 - 0.24 11.1 9.3 1.5 8.5 9.3 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.7 KIK52570.1 - 0.26 11.5 9.2 2.4 8.3 8.5 1.9 1 1 0 1 1 1 0 Tropomyosin like LPP PF04728.13 KIK52570.1 - 0.41 11.1 3.3 5 7.6 0.5 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 KIK52570.1 - 0.42 10.7 7.2 4.5 7.3 7.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dzip-like_N PF13815.6 KIK52570.1 - 1.1 9.3 8.6 1.7 8.6 0.9 2.0 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Swi5 PF07061.11 KIK52570.1 - 1.3 9.2 5.9 11 6.2 1.0 2.1 2 0 0 2 2 2 0 Swi5 Cep57_CLD_2 PF14197.6 KIK52570.1 - 2 8.5 10.1 11 6.2 9.4 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Rho_Binding PF08912.11 KIK52570.1 - 2.2 9.2 7.9 13 6.7 0.6 2.1 2 0 0 2 2 2 0 Rho Binding Zein-binding PF04576.15 KIK52570.1 - 3.8 7.9 9.7 0.94 9.8 4.6 2.0 2 0 0 2 2 2 0 Zein-binding Bap31_Bap29_C PF18035.1 KIK52570.1 - 5.4 7.1 10.4 1.1 9.3 1.7 2.4 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain BAR_3 PF16746.5 KIK52571.1 - 0.0093 15.7 3.9 0.13 11.9 0.7 2.1 2 0 0 2 2 2 2 BAR domain of APPL family HMMR_N PF15905.5 KIK52571.1 - 0.04 13.4 1.4 0.065 12.7 1.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DivIC PF04977.15 KIK52573.1 - 0.057 13.2 1.2 0.16 11.7 1.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4763 PF15960.5 KIK52573.1 - 0.24 10.7 5.5 1 8.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) DUF1690 PF07956.11 KIK52573.1 - 0.47 10.9 4.3 0.3 11.5 1.7 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) CCDC144C PF14915.6 KIK52573.1 - 0.64 9.1 5.2 0.11 11.5 1.6 1.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region JmjC PF02373.22 KIK52575.1 - 2.2e-07 31.3 0.2 6.6e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Gti1_Pac2 PF09729.9 KIK52577.1 - 2.1e-29 102.9 0.2 9.3e-21 74.7 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family CLZ PF16526.5 KIK52579.1 - 0.00011 22.5 0.6 0.00011 22.5 0.6 3.0 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 KIK52579.1 - 0.00029 20.8 2.5 0.00029 20.8 2.5 2.7 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 KIK52579.1 - 0.00031 20.9 17.1 0.019 15.2 1.6 2.9 2 1 0 2 2 2 2 ABC transporter C-terminal domain CCDC144C PF14915.6 KIK52579.1 - 0.00037 19.7 19.7 0.00037 19.7 0.7 2.1 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region FlxA PF14282.6 KIK52579.1 - 0.00043 20.2 13.3 0.12 12.4 7.6 2.2 2 0 0 2 2 2 2 FlxA-like protein Jnk-SapK_ap_N PF09744.9 KIK52579.1 - 0.0007 19.9 14.9 0.078 13.2 1.1 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 Lebercilin PF15619.6 KIK52579.1 - 0.0014 18.3 16.9 0.015 14.9 8.7 2.2 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Lzipper-MIP1 PF14389.6 KIK52579.1 - 0.0092 16.3 9.4 0.26 11.6 0.6 2.5 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 EzrA PF06160.12 KIK52579.1 - 0.012 13.8 9.7 0.45 8.6 0.3 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 KIK52579.1 - 0.013 16.0 22.3 0.016 15.7 0.7 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF5595 PF18077.1 KIK52579.1 - 0.013 15.5 1.4 0.013 15.5 1.4 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF5595) DUF3156 PF11354.8 KIK52579.1 - 0.017 15.1 0.6 1 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) Fib_alpha PF08702.10 KIK52579.1 - 0.017 15.3 9.6 0.66 10.2 4.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KIK52579.1 - 0.024 14.7 0.5 4.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 KIK52579.1 - 0.026 14.4 9.0 0.94 9.3 0.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 GrpE PF01025.19 KIK52579.1 - 0.026 14.2 12.7 0.042 13.5 0.8 2.3 2 0 0 2 2 2 0 GrpE DUF4140 PF13600.6 KIK52579.1 - 0.026 14.9 9.9 0.06 13.8 0.2 2.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.6 KIK52579.1 - 0.03 14.7 16.0 0.14 12.6 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CpG_bind_C PF12269.8 KIK52579.1 - 0.04 13.7 13.4 0.12 12.1 7.3 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF5082 PF16888.5 KIK52579.1 - 0.043 14.1 15.0 1.3 9.3 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 KIK52579.1 - 0.043 14.2 1.2 0.043 14.2 1.2 2.7 2 1 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 KIK52579.1 - 0.055 13.6 3.0 0.055 13.6 3.0 3.2 2 1 0 3 3 3 0 Basic region leucine zipper DUF16 PF01519.16 KIK52579.1 - 0.056 13.9 8.8 4.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4472 PF14739.6 KIK52579.1 - 0.06 14.1 1.4 0.06 14.1 1.4 2.5 2 1 0 2 2 1 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.9 KIK52579.1 - 0.082 13.2 11.3 0.14 12.5 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 KIK52579.1 - 0.088 13.2 0.8 0.088 13.2 0.8 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2203 PF09969.9 KIK52579.1 - 0.1 13.3 8.9 0.31 11.8 3.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CC2-LZ PF16516.5 KIK52579.1 - 0.1 13.0 0.8 0.1 13.0 0.8 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator OmpH PF03938.14 KIK52579.1 - 0.11 12.9 14.1 0.094 13.0 7.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 KIK52579.1 - 0.11 12.5 16.1 0.12 12.4 0.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit MbeD_MobD PF04899.12 KIK52579.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.4 2 1 0 2 2 2 0 MbeD/MobD like Cluap1 PF10234.9 KIK52579.1 - 0.12 11.8 13.5 0.16 11.3 0.6 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 TPR_MLP1_2 PF07926.12 KIK52579.1 - 0.12 12.4 17.6 1.3 9.1 9.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KIK52579.1 - 0.13 12.8 5.7 0.66 10.5 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 KIK52579.1 - 0.13 12.0 6.1 2.5 7.9 1.6 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HAUS-augmin3 PF14932.6 KIK52579.1 - 0.16 11.6 13.3 0.77 9.3 6.5 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 KIK52579.1 - 0.16 11.3 13.4 0.24 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BBP1_C PF15272.6 KIK52579.1 - 0.18 11.6 9.0 0.46 10.3 3.8 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal CASP_C PF08172.12 KIK52579.1 - 0.19 11.0 8.2 0.099 12.0 1.6 2.1 2 0 0 2 2 2 0 CASP C terminal HMMR_N PF15905.5 KIK52579.1 - 0.2 11.1 14.8 0.67 9.4 8.3 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 KIK52579.1 - 0.24 11.6 17.3 0.44 10.7 1.5 2.4 2 0 0 2 2 2 0 Tropomyosin like CENP-Q PF13094.6 KIK52579.1 - 0.26 11.5 12.4 1.1 9.5 0.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.6 KIK52579.1 - 0.27 10.6 20.4 0.22 10.9 1.8 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KIK52579.1 - 0.3 11.3 17.0 0.36 11.0 0.9 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 KIK52579.1 - 0.33 10.8 16.5 0.28 11.0 0.4 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF2730 PF10805.8 KIK52579.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) LMBR1 PF04791.16 KIK52579.1 - 0.46 9.3 5.6 0.59 9.0 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4391 PF14335.6 KIK52579.1 - 0.46 10.2 10.6 1.5 8.5 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Phasin PF05597.11 KIK52579.1 - 0.49 10.4 8.1 6.1 6.9 2.8 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4201 PF13870.6 KIK52579.1 - 0.49 10.1 16.7 0.75 9.5 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GPS2_interact PF15784.5 KIK52579.1 - 0.53 10.8 15.1 0.53 10.8 0.3 2.5 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF724 PF05266.14 KIK52579.1 - 0.54 10.1 12.4 2.5 7.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) BRE1 PF08647.11 KIK52579.1 - 0.63 10.1 17.7 0.31 11.1 1.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Med4 PF10018.9 KIK52579.1 - 0.67 9.6 10.1 0.93 9.1 3.5 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Filament PF00038.21 KIK52579.1 - 0.67 9.5 16.7 0.68 9.5 0.6 2.1 2 0 0 2 2 2 0 Intermediate filament protein Osmo_CC PF08946.10 KIK52579.1 - 0.78 10.0 0.1 0.78 10.0 0.1 3.1 2 1 1 3 3 2 0 Osmosensory transporter coiled coil Cep57_MT_bd PF06657.13 KIK52579.1 - 0.88 10.1 12.1 1.3 9.5 0.3 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ax_dynein_light PF10211.9 KIK52579.1 - 0.92 9.4 17.6 0.12 12.3 0.7 2.4 2 1 0 2 2 2 0 Axonemal dynein light chain Prominin PF05478.11 KIK52579.1 - 0.97 7.3 7.5 0.69 7.8 4.5 1.8 2 0 0 2 2 2 0 Prominin ADIP PF11559.8 KIK52579.1 - 0.97 9.5 16.6 0.22 11.6 1.5 2.5 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KIK52579.1 - 1.1 9.6 11.4 1.7 9.0 5.7 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4094 PF13334.6 KIK52579.1 - 1.2 9.6 11.1 0.77 10.2 0.5 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4094) PEARLI-4 PF05278.12 KIK52579.1 - 1.5 8.4 14.1 0.29 10.7 0.2 2.4 2 1 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DHR10 PF18595.1 KIK52579.1 - 1.5 8.9 19.3 0.27 11.3 2.1 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Fzo_mitofusin PF04799.13 KIK52579.1 - 1.8 8.1 10.5 4.3 6.9 5.1 2.4 2 1 0 2 2 2 0 fzo-like conserved region UPF0242 PF06785.11 KIK52579.1 - 1.9 8.6 16.5 5.2 7.1 9.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ACCA PF03255.14 KIK52579.1 - 1.9 8.3 8.3 4.8 7.0 3.2 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc7 PF08317.11 KIK52579.1 - 2.1 7.2 17.8 1.1 8.1 1.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KIK52579.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.2 2 1 0 2 2 1 0 Flagella accessory protein C (FlaC) Stathmin PF00836.19 KIK52579.1 - 2.1 8.3 14.5 0.32 11.0 6.1 2.3 2 0 0 2 2 2 0 Stathmin family Prefoldin PF02996.17 KIK52579.1 - 2.6 8.0 14.0 1.2 9.1 0.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit SlyX PF04102.12 KIK52579.1 - 2.6 8.7 10.7 2.1 9.1 0.2 2.9 2 1 0 2 2 2 0 SlyX MYO10_CC PF16735.5 KIK52579.1 - 2.8 8.1 16.5 14 5.9 12.2 3.2 2 1 1 3 3 3 0 Unconventional myosin-X coiled coil domain DUF2408 PF10303.9 KIK52579.1 - 2.9 8.5 11.2 7.5 7.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Spc24 PF08286.11 KIK52579.1 - 3 8.1 15.3 0.16 12.2 0.9 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TRAF_BIRC3_bd PF16673.5 KIK52579.1 - 3.3 7.6 12.1 1.7 8.5 0.1 3.1 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain GTA_holin_3TM PF11351.8 KIK52579.1 - 3.3 8.3 7.7 2.2 8.9 1.8 2.4 2 1 0 2 2 2 0 Holin of 3TMs, for gene-transfer release AAA_13 PF13166.6 KIK52579.1 - 3.6 6.1 15.5 2.6 6.6 7.3 2.1 1 1 1 2 2 2 0 AAA domain BRI3BP PF14965.6 KIK52579.1 - 4.9 6.6 5.6 1 8.8 0.1 2.4 2 1 1 3 3 3 0 Negative regulator of p53/TP53 HR1 PF02185.16 KIK52579.1 - 6.3 7.0 17.1 5.5 7.2 2.6 3.4 2 1 1 3 3 3 0 Hr1 repeat JIP_LZII PF16471.5 KIK52579.1 - 9.1 6.5 13.1 11 6.2 4.5 2.8 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF4218 PF13960.6 KIK52582.1 - 0.0094 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) GAS PF13851.6 KIK52583.1 - 0.01 15.2 31.0 0.13 11.6 15.9 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KIK52583.1 - 0.025 14.7 3.2 0.025 14.7 3.2 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 KIK52583.1 - 0.36 9.9 25.3 0.62 9.1 10.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 KIK52583.1 - 0.87 9.9 32.5 0.56 10.5 3.7 3.7 2 2 1 3 3 3 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 KIK52583.1 - 1.3 9.2 31.3 0.8 9.9 20.5 2.8 2 1 1 3 3 3 0 Tropomyosin like DUF4201 PF13870.6 KIK52583.1 - 1.7 8.3 30.2 0.53 10.0 15.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 KIK52583.1 - 2.1 8.4 34.4 0.3 11.2 17.4 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KIK52583.1 - 3.1 8.2 27.9 1.7 9.1 15.0 2.2 1 1 1 2 2 2 0 Fez1 TSNAXIP1_N PF15739.5 KIK52583.1 - 4.5 7.7 27.1 0.062 13.7 4.5 3.3 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus HMMR_N PF15905.5 KIK52583.1 - 4.9 6.5 33.6 0.14 11.6 17.8 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 KIK52583.1 - 5.1 7.6 36.8 4.7 7.7 7.4 3.2 1 1 1 2 2 1 0 Apg6 coiled-coil region Dynamin_N PF00350.23 KIK52583.1 - 7.2 6.6 13.9 60 3.6 12.0 2.6 1 1 1 2 2 2 0 Dynamin family THOC7 PF05615.13 KIK52583.1 - 7.8 6.8 27.0 3.5 7.9 11.1 3.3 1 1 2 3 3 3 0 Tho complex subunit 7 Spc7 PF08317.11 KIK52583.1 - 8.7 5.1 33.0 8.9 5.1 6.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 KIK52584.1 - 0.037 14.5 1.9 0.037 14.5 1.9 3.8 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins KRE1 PF17056.5 KIK52584.1 - 0.17 11.7 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 YtxH PF12732.7 KIK52584.1 - 0.76 10.3 12.9 0.14 12.7 0.9 2.8 3 1 0 3 3 3 0 YtxH-like protein TPR_MLP1_2 PF07926.12 KIK52584.1 - 0.87 9.6 27.1 1.1 9.3 18.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KIK52584.1 - 1.3 7.9 24.3 0.35 9.7 19.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Vfa1 PF08432.10 KIK52584.1 - 1.3 9.3 17.4 1.8 8.9 17.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDPS PF16715.5 KIK52584.1 - 1.8 8.1 5.5 0.68 9.6 2.8 1.6 1 1 1 2 2 2 0 Cyclodipeptide synthase Fez1 PF06818.15 KIK52584.1 - 1.9 8.9 21.8 10 6.5 21.8 2.1 1 1 0 1 1 1 0 Fez1 APG6_N PF17675.1 KIK52584.1 - 2.2 8.8 29.3 5.7 7.5 9.7 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KIK52584.1 - 2.7 8.2 16.4 7.1 6.8 3.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CortBP2 PF09727.9 KIK52584.1 - 4.4 7.2 23.5 0.052 13.5 12.2 2.5 1 1 1 3 3 3 0 Cortactin-binding protein-2 Interferon PF00143.19 KIK52584.1 - 4.6 7.4 12.5 0.13 12.4 3.6 2.2 1 1 1 2 2 2 0 Interferon alpha/beta domain CorA PF01544.18 KIK52584.1 - 5.2 6.3 7.6 5.3 6.3 6.2 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein KIAA1430 PF13879.6 KIK52584.1 - 5.3 7.9 16.7 1.2e+02 3.5 16.7 2.6 1 1 0 1 1 1 0 KIAA1430 homologue FlaC_arch PF05377.11 KIK52584.1 - 5.9 7.4 13.8 20 5.6 0.4 4.3 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KIK52584.1 - 8.5 7.1 19.4 6e+02 1.2 0.1 3.3 1 1 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 KIK52585.1 - 4.5e-05 23.1 10.6 0.04 13.7 0.5 3.0 2 1 0 2 2 2 2 Septum formation initiator GAS PF13851.6 KIK52585.1 - 0.00043 19.7 6.4 0.0092 15.3 0.7 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 KIK52585.1 - 0.00061 19.5 10.7 0.017 14.8 1.0 2.1 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 KIK52585.1 - 0.00098 19.5 7.2 0.22 11.9 2.2 2.9 2 1 0 2 2 2 2 Flagella accessory protein C (FlaC) ZapB PF06005.12 KIK52585.1 - 0.0011 19.4 10.1 0.019 15.4 2.3 2.4 2 0 0 2 2 2 2 Cell division protein ZapB YabA PF06156.13 KIK52585.1 - 0.0012 19.4 6.7 0.046 14.4 2.0 2.1 1 1 1 2 2 2 1 Initiation control protein YabA KASH_CCD PF14662.6 KIK52585.1 - 0.0014 18.5 12.4 0.058 13.2 2.9 2.0 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KIK52585.1 - 0.0048 17.0 13.1 0.18 12.0 3.3 3.2 2 1 1 3 3 3 2 bZIP transcription factor CENP-F_leu_zip PF10473.9 KIK52585.1 - 0.0078 16.2 8.4 0.32 11.0 1.6 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XRCC4 PF06632.12 KIK52585.1 - 0.0088 14.9 4.7 0.019 13.9 1.0 2.0 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 APG6_N PF17675.1 KIK52585.1 - 0.0092 16.5 18.6 0.31 11.6 5.3 2.0 1 1 1 2 2 2 2 Apg6 coiled-coil region Cnn_1N PF07989.11 KIK52585.1 - 0.0095 16.1 7.4 0.0099 16.0 2.5 2.4 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 KIK52585.1 - 0.011 15.1 6.9 0.3 10.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HAT_KAT11 PF08214.11 KIK52585.1 - 0.013 14.8 1.4 0.014 14.6 1.4 1.1 1 0 0 1 1 1 0 Histone acetylation protein CtIP_N PF10482.9 KIK52585.1 - 0.014 15.4 5.7 0.97 9.5 1.0 2.3 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF1319 PF07028.11 KIK52585.1 - 0.027 14.7 1.5 0.082 13.1 1.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) SHE3 PF17078.5 KIK52585.1 - 0.033 13.9 5.7 0.074 12.8 1.2 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KIK52585.1 - 0.037 14.1 11.0 1.4 9.1 0.7 3.3 2 2 1 3 3 3 0 Basic region leucine zipper DUF4201 PF13870.6 KIK52585.1 - 0.04 13.6 8.8 0.4 10.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMCO5 PF14992.6 KIK52585.1 - 0.047 13.3 6.1 0.062 12.9 6.1 1.3 1 0 0 1 1 1 0 TMCO5 family PspA_IM30 PF04012.12 KIK52585.1 - 0.048 13.2 8.7 0.19 11.3 8.7 1.7 1 1 0 1 1 1 0 PspA/IM30 family HALZ PF02183.18 KIK52585.1 - 0.056 13.7 10.6 0.67 10.2 0.2 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper Rootletin PF15035.6 KIK52585.1 - 0.059 13.4 11.2 0.053 13.5 1.7 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HOOK PF05622.12 KIK52585.1 - 0.064 11.4 7.7 0.14 10.3 7.7 1.5 1 1 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 KIK52585.1 - 0.067 13.3 14.1 0.55 10.3 3.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 KIK52585.1 - 0.072 13.0 9.9 0.61 10.0 0.1 3.2 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region IFT57 PF10498.9 KIK52585.1 - 0.095 11.7 5.5 0.27 10.2 0.5 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 BRE1 PF08647.11 KIK52585.1 - 0.11 12.5 10.6 0.38 10.9 4.0 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2968 PF11180.8 KIK52585.1 - 0.12 12.0 3.4 1.8 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4795 PF16043.5 KIK52585.1 - 0.13 11.8 5.0 3.4 7.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 KIK52585.1 - 0.17 12.2 8.1 0.13 12.6 1.2 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 PRKG1_interact PF15898.5 KIK52585.1 - 0.21 12.5 12.0 1.9 9.4 0.3 3.0 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 KIK52585.1 - 0.23 11.8 8.0 1.6 9.1 1.0 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family Fungal_TACC PF12709.7 KIK52585.1 - 0.25 11.8 7.3 4.9 7.7 0.2 2.6 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cep57_CLD_2 PF14197.6 KIK52585.1 - 0.27 11.3 11.6 0.14 12.3 2.4 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 RasGAP_C PF03836.15 KIK52585.1 - 0.3 11.2 6.4 5.7 7.1 1.9 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Chibby PF14645.6 KIK52585.1 - 0.38 11.2 4.5 5.9 7.3 1.3 2.4 1 1 1 2 2 2 0 Chibby family DUF4337 PF14235.6 KIK52585.1 - 0.39 10.8 4.9 1.1 9.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF4140 PF13600.6 KIK52585.1 - 0.51 10.8 4.3 9.9 6.7 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 KIK52585.1 - 0.55 10.3 9.6 3.2 7.8 1.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KIK52585.1 - 0.58 10.2 18.1 0.12 12.3 7.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding JIP_LZII PF16471.5 KIK52585.1 - 0.64 10.2 11.8 1.4 9.1 2.4 2.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 KIK52585.1 - 0.67 10.2 13.5 12 6.1 13.2 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 KIK52585.1 - 0.72 10.3 12.2 2.8 8.4 7.8 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BST2 PF16716.5 KIK52585.1 - 0.9 10.2 8.6 0.4 11.3 1.7 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PI3K_P85_iSH2 PF16454.5 KIK52585.1 - 1 8.9 8.0 0.54 9.8 1.2 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KfrA_N PF11740.8 KIK52585.1 - 1.1 9.9 6.5 13 6.5 0.1 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIVA PF05103.13 KIK52585.1 - 1.4 9.0 9.3 0.48 10.5 1.8 2.3 2 1 0 2 2 2 0 DivIVA protein M PF02370.16 KIK52585.1 - 1.4 9.7 0.1 1.4 9.7 0.1 3.6 4 0 0 4 4 2 0 M protein repeat Prefoldin_2 PF01920.20 KIK52585.1 - 1.5 8.8 11.5 1.8 8.6 0.9 2.5 2 1 0 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 KIK52585.1 - 1.6 7.8 9.4 4 6.4 9.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5320 PF17253.2 KIK52585.1 - 2.8 9.1 6.9 20 6.3 1.5 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Rubis-subs-bind PF09273.11 KIK52585.1 - 3 8.5 9.0 60 4.3 8.9 2.1 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding FPP PF05911.11 KIK52585.1 - 3.8 5.6 15.1 18 3.4 15.1 1.8 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DMPK_coil PF08826.10 KIK52585.1 - 5.5 7.2 12.5 3.8 7.7 2.3 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF724 PF05266.14 KIK52585.1 - 5.7 6.7 9.4 44 3.8 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NYD-SP28_assoc PF14775.6 KIK52585.1 - 5.7 7.1 9.0 15 5.7 0.1 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain HIP1_clath_bdg PF16515.5 KIK52585.1 - 6.9 7.4 13.2 6.5 7.4 2.3 2.3 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Uso1_p115_C PF04871.13 KIK52585.1 - 8.7 6.7 15.4 2.1e+02 2.2 15.4 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Peptidase_C48 PF02902.19 KIK52589.1 - 7.1e-13 48.9 0.0 8.1e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C39 PF03412.15 KIK52589.1 - 0.043 13.6 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase C39 family Hex_IIIa PF02455.16 KIK52589.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Cupin_4 PF08007.12 KIK52592.1 - 0.012 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 KIK52592.1 - 0.09 13.2 0.5 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase ANAPC4_WD40 PF12894.7 KIK52594.1 - 0.093 13.0 0.0 25 5.2 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NPV_P10 PF05531.12 KIK52595.1 - 0.053 14.0 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 KIK52595.1 - 1.5 9.5 4.5 3.9 8.3 1.2 2.4 1 1 1 2 2 2 0 Occludin homology domain AAA_lid_3 PF17862.1 KIK52597.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA+ lid domain YrbL-PhoP_reg PF10707.9 KIK52598.1 - 0.079 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SHMT PF00464.19 KIK52599.1 - 0.086 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase RNA_polI_A34 PF08208.11 KIK52602.1 - 0.98 9.5 19.3 1.2 9.1 19.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ExbD PF02472.16 KIK52602.1 - 1.8 8.7 4.5 2.8 8.1 4.5 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Nop14 PF04147.12 KIK52602.1 - 2.1 6.4 34.9 2.5 6.2 34.9 1.0 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 KIK52602.1 - 3.9 5.5 8.1 4.4 5.3 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 KIK52602.1 - 6.4 5.4 11.7 7.2 5.3 11.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 KIK52602.1 - 7 5.5 9.3 8.1 5.4 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 BAR_3 PF16746.5 KIK52608.1 - 0.0067 16.2 3.0 0.0067 16.2 3.0 2.0 2 0 0 2 2 2 1 BAR domain of APPL family TSNAXIP1_N PF15739.5 KIK52608.1 - 0.012 16.0 2.4 0.022 15.1 2.4 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TED_complement PF07678.14 KIK52608.1 - 0.014 14.5 0.2 0.019 14.0 0.2 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF648 PF04890.13 KIK52608.1 - 0.014 15.2 0.4 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF327 PF03885.13 KIK52608.1 - 0.021 14.8 0.6 0.037 14.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF3584 PF12128.8 KIK52608.1 - 0.028 12.0 5.1 0.037 11.6 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 KIK52608.1 - 0.094 12.6 4.9 2.9 7.8 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 KIK52608.1 - 0.14 11.6 8.0 0.23 10.9 8.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4335 PF14233.6 KIK52608.1 - 0.2 11.6 3.0 0.35 10.8 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF745 PF05335.13 KIK52608.1 - 0.25 11.1 4.8 5.4 6.7 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 KIK52608.1 - 0.49 10.5 7.0 0.84 9.7 7.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KIK52608.1 - 0.74 10.0 5.4 2.3 8.4 5.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_S49_N PF08496.10 KIK52609.1 - 0.001 19.1 0.5 0.002 18.2 0.5 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK52609.1 - 0.0016 17.4 10.5 0.0023 16.9 10.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec2p PF06428.11 KIK52609.1 - 0.018 15.0 2.1 0.018 15.0 2.1 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Bacillus_HBL PF05791.11 KIK52609.1 - 0.052 13.4 2.8 0.28 11.0 1.6 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PKcGMP_CC PF16808.5 KIK52609.1 - 0.15 11.9 6.0 3.2 7.7 0.4 2.9 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 KIK52609.1 - 0.29 11.2 1.5 0.53 10.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc42p PF11544.8 KIK52609.1 - 0.33 11.0 2.9 10 6.2 2.6 2.5 1 1 0 1 1 1 0 Spindle pole body component Spc42p Phage_GP20 PF06810.11 KIK52609.1 - 0.41 10.5 9.0 2.3 8.0 0.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 KASH_CCD PF14662.6 KIK52609.1 - 0.42 10.4 12.2 0.7 9.7 12.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Med9 PF07544.13 KIK52609.1 - 0.46 10.6 4.1 1 9.5 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Csm1_N PF18504.1 KIK52609.1 - 0.73 10.2 12.7 2.7 8.4 3.4 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 KIK52609.1 - 1 9.6 3.9 3.6 7.8 2.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KIK52609.1 - 1.2 8.9 7.7 3.6 7.3 2.6 3.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 KIK52609.1 - 1.2 8.3 4.1 1.9 7.6 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 KIK52609.1 - 2.5 8.2 11.3 1.9 8.6 6.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIK52609.1 - 5.5 7.1 17.8 3.5 7.7 2.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KIK52609.1 - 8.3 5.7 6.8 12 5.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gypsy PF07253.11 KIK52616.1 - 0.022 13.3 0.0 0.041 12.4 0.0 1.4 1 0 0 1 1 1 0 Gypsy protein DUF4218 PF13960.6 KIK52616.1 - 0.055 13.1 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HMw1_D2 PF18254.1 KIK52618.1 - 0.0048 17.2 0.7 0.24 11.8 0.0 3.2 2 1 1 3 3 3 1 HMW1 domain 2 WD40 PF00400.32 KIK52621.1 - 7.4e-06 26.6 1.7 2.9e-05 24.7 0.0 2.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK52621.1 - 0.0033 17.7 0.0 0.0067 16.7 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4479 PF14794.6 KIK52621.1 - 0.17 11.8 0.1 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Spt5_N PF11942.8 KIK52622.1 - 0.054 14.5 0.4 0.11 13.5 0.4 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal KDZ PF18758.1 KIK52624.1 - 7.9e-11 42.0 0.6 8.1e-11 41.9 0.6 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CDC4_D PF16856.5 KIK52624.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain PepSY_2 PF13670.6 KIK52626.1 - 0.86 9.7 4.1 0.84 9.7 2.3 2.0 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain DUF3335 PF11814.8 KIK52628.1 - 0.099 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase_C39 like family Glyco_hydro_75 PF07335.11 KIK52629.1 - 1.4e-34 119.7 0.5 2.2e-34 119.1 0.5 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF719 PF05334.13 KIK52629.1 - 0.052 13.7 0.6 0.079 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Macoilin PF09726.9 KIK52629.1 - 4.5 5.7 5.0 5.1 5.5 5.0 1.1 1 0 0 1 1 1 0 Macoilin family FeoB_Cyto PF17910.1 KIK52630.1 - 0.12 12.9 0.2 0.27 11.8 0.2 1.5 1 0 0 1 1 1 0 FeoB cytosolic helical domain Ferric_reduct PF01794.19 KIK52631.1 - 9.6e-19 67.7 10.8 9.6e-19 67.7 10.8 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK52631.1 - 5.4e-11 42.6 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIK52631.1 - 2.4e-09 37.5 0.0 3.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KIK52631.1 - 0.12 13.1 0.0 1.5 9.5 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain HN PF00423.19 KIK52632.1 - 0.021 13.6 0.1 0.024 13.5 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase HN PF00423.19 KIK52634.1 - 0.013 14.4 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Spem1 PF15670.5 KIK52634.1 - 0.076 12.6 0.5 0.12 12.0 0.5 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 MARVEL PF01284.23 KIK52636.1 - 7.5e-10 39.0 11.5 9.5e-10 38.7 11.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DDE_Tnp_IS66_C PF13817.6 KIK52636.1 - 0.095 12.9 0.1 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 IS66 C-terminal element DUF373 PF04123.13 KIK52636.1 - 0.42 10.0 2.5 0.5 9.8 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) NACHT PF05729.12 KIK52637.1 - 3.3e-06 27.1 0.0 3.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK52637.1 - 0.0011 19.2 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK52637.1 - 0.0015 19.0 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK52637.1 - 0.0017 18.7 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 RNA helicase APS_kinase PF01583.20 KIK52637.1 - 0.0033 17.3 0.1 0.0076 16.2 0.0 1.5 1 1 0 1 1 1 1 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK52637.1 - 0.0034 16.5 0.3 0.0049 16.0 0.3 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KIK52637.1 - 0.0066 16.6 0.1 0.0081 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK52637.1 - 0.017 15.7 0.1 0.021 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK52637.1 - 0.022 14.5 0.4 0.036 13.8 0.2 1.4 1 1 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 KIK52637.1 - 0.023 15.2 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KIK52637.1 - 0.032 14.0 0.5 0.072 12.8 0.2 1.6 1 1 0 2 2 2 0 IstB-like ATP binding protein Thymidylate_kin PF02223.17 KIK52637.1 - 0.046 13.4 0.2 0.91 9.2 0.1 2.0 1 1 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 KIK52637.1 - 0.052 14.0 0.1 0.072 13.5 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK52637.1 - 0.052 13.1 0.0 0.073 12.6 0.0 1.3 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KIK52637.1 - 0.056 13.1 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK52637.1 - 0.12 11.8 0.4 0.27 10.7 0.3 1.6 1 1 1 2 2 2 0 PhoH-like protein EutK_C PF16365.5 KIK52637.1 - 0.15 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Rad17 PF03215.15 KIK52637.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_10 PF12846.7 KIK52637.1 - 0.18 10.7 0.0 0.2 10.5 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.6 KIK52637.1 - 0.18 11.3 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain HTH_27 PF13463.6 KIK52639.1 - 0.068 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Phage_min_cap2 PF06152.11 KIK52639.1 - 0.21 10.4 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 zf-C2H2 PF00096.26 KIK52642.1 - 5.9e-09 35.9 9.0 0.00013 22.2 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK52642.1 - 6.6e-07 29.5 15.1 3.7e-06 27.1 2.0 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK52642.1 - 8.2e-05 23.1 7.8 0.094 13.6 1.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK52642.1 - 0.0041 17.7 0.4 0.39 11.4 0.0 2.5 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KIK52642.1 - 0.28 11.3 0.5 2.8 8.0 0.7 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger ABC_tran_CTD PF16326.5 KIK52644.1 - 0.0024 18.1 0.2 0.0027 17.9 0.2 1.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 KIK52644.1 - 0.013 15.6 0.0 0.015 15.5 0.0 1.0 1 0 0 1 1 1 0 Tropomyosin like DUF3450 PF11932.8 KIK52644.1 - 0.021 14.1 0.1 0.023 14.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1192 PF06698.11 KIK52644.1 - 0.022 14.8 1.1 0.13 12.3 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 KIK52644.1 - 0.025 14.2 0.2 0.025 14.2 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 KIK52644.1 - 0.025 15.2 0.2 0.034 14.7 0.2 1.3 1 1 0 1 1 1 0 SlyX Mod_r PF07200.13 KIK52644.1 - 0.027 14.6 0.1 0.03 14.4 0.1 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 KIK52644.1 - 0.028 14.5 0.2 0.029 14.4 0.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 KIK52644.1 - 0.039 14.3 0.2 0.049 14.0 0.2 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKA1 PF07160.12 KIK52644.1 - 0.059 13.2 0.0 0.059 13.2 0.0 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Golgin_A5 PF09787.9 KIK52644.1 - 0.06 12.8 0.0 0.063 12.7 0.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc24 PF08286.11 KIK52644.1 - 0.084 13.1 0.1 0.087 13.1 0.1 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DASH_Hsk3 PF08227.11 KIK52644.1 - 0.085 13.2 1.3 0.093 13.1 0.6 1.4 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like Lzipper-MIP1 PF14389.6 KIK52644.1 - 0.091 13.1 1.6 0.16 12.2 1.6 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 LPP PF04728.13 KIK52644.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper F-box-like PF12937.7 KIK52645.1 - 3.4e-05 23.6 1.2 7.9e-05 22.5 1.2 1.7 1 1 0 1 1 1 1 F-box-like TMF_TATA_bd PF12325.8 KIK52645.1 - 0.013 15.7 0.2 0.017 15.3 0.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GCSF PF16647.5 KIK52645.1 - 0.047 13.6 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor DUF4140 PF13600.6 KIK52645.1 - 0.15 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SPT2 PF08243.11 KIK52646.1 - 9.5e-18 64.8 17.0 9.5e-18 64.8 17.0 3.9 3 1 0 3 3 3 1 SPT2 chromatin protein MFS_1 PF07690.16 KIK52647.1 - 2e-31 109.2 32.1 5.9e-25 87.9 3.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK52647.1 - 6.4e-05 22.0 23.6 6.8e-05 21.9 8.4 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter DNA_pol_A_exo1 PF01612.20 KIK52648.1 - 8.7e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DZR PF12773.7 KIK52648.1 - 0.11 12.6 3.1 0.21 11.6 3.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 KIK52648.1 - 0.2 12.2 1.8 0.4 11.2 1.8 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-ISL3 PF14690.6 KIK52648.1 - 2.3 8.9 5.7 4.1 8.2 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Mut7-C PF01927.16 KIK52649.1 - 0.036 14.2 6.8 0.033 14.3 5.3 1.7 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF1540 PF07561.11 KIK52649.1 - 2.6 8.4 8.5 15 6.0 6.3 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1540) Retrotran_gag_3 PF14244.6 KIK52650.1 - 9.1e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MFS_1 PF07690.16 KIK52651.1 - 5.3e-20 71.6 7.7 1.9e-14 53.4 1.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK52651.1 - 5.3e-05 22.3 0.2 5.3e-05 22.3 0.2 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK52651.1 - 0.00012 20.7 0.1 0.00016 20.2 0.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KIK52652.1 - 2.7e-35 121.9 50.1 1.4e-31 109.7 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK52652.1 - 1.8e-07 30.4 13.5 4.4e-07 29.1 13.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK52652.1 - 0.00025 19.6 0.3 0.00047 18.7 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KIK52653.1 - 1.9e-31 109.3 33.7 1.7e-23 83.1 3.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK52653.1 - 2.5e-06 26.7 19.0 5.3e-06 25.6 19.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK52653.1 - 0.0012 17.8 18.4 0.0025 16.8 1.6 2.9 2 1 0 2 2 2 2 MFS_1 like family Amidohydro_1 PF01979.20 KIK52654.1 - 1.3e-69 235.1 1.3 1.9e-69 234.6 1.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KIK52654.1 - 1.7e-56 189.8 1.8 3.4e-56 188.8 1.8 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KIK52654.1 - 4e-42 142.2 0.0 9.4e-42 141.0 0.0 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KIK52654.1 - 1.5e-40 137.5 0.2 5.1e-40 135.8 0.1 2.1 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KIK52654.1 - 0.0018 17.8 0.3 0.013 15.0 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family PQ-loop PF04193.14 KIK52655.1 - 1.7e-31 107.7 11.2 4.2e-18 64.9 0.3 3.0 3 1 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 KIK52655.1 - 0.072 13.1 6.0 0.16 12.0 1.0 2.6 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange TMEM100 PF16311.5 KIK52655.1 - 0.086 12.4 0.0 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 100 LAB_N PF07578.11 KIK52655.1 - 0.8 9.8 6.8 0.66 10.1 1.4 2.5 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Peptidase_U4 PF03419.13 KIK52655.1 - 1.5 8.0 6.0 3.4 6.9 6.0 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Med3 PF11593.8 KIK52656.1 - 0.012 14.8 1.2 0.018 14.2 1.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 KIK52657.1 - 1.4e-29 103.2 66.4 2.6e-28 99.0 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK52657.1 - 0.00013 21.0 24.9 0.0019 17.1 24.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter NinF PF05810.12 KIK52658.1 - 0.12 12.3 0.4 0.12 12.3 0.4 2.0 2 0 0 2 2 2 0 NinF protein CHORD PF04968.12 KIK52658.1 - 0.12 13.1 1.0 0.12 13.1 1.0 2.7 2 1 0 2 2 2 0 CHORD zf-C2HC_2 PF13913.6 KIK52659.1 - 0.046 13.6 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Kelch_6 PF13964.6 KIK52660.1 - 8.8e-24 82.9 13.2 3.2e-06 27.2 0.1 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KIK52660.1 - 6.6e-16 58.1 14.1 0.0016 18.4 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KIK52660.1 - 3.8e-15 55.2 6.7 7.3e-05 22.3 0.2 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KIK52660.1 - 3.1e-14 52.6 4.9 0.0016 18.4 0.1 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KIK52660.1 - 1.1e-11 44.7 19.9 0.014 15.7 0.0 7.4 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KIK52660.1 - 1.2e-11 44.0 10.8 0.02 14.8 1.3 6.7 6 2 0 6 6 6 3 Kelch motif zf-MYND PF01753.18 KIK52660.1 - 0.0024 17.9 14.7 0.0048 17.0 14.7 1.5 1 0 0 1 1 1 1 MYND finger YHS PF04945.13 KIK52660.1 - 0.0086 16.2 0.4 0.73 10.0 2.3 2.6 2 0 0 2 2 2 1 YHS domain zf-C6H2 PF15801.5 KIK52660.1 - 0.097 13.0 14.7 0.47 10.8 14.7 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PPI_Ypi1 PF07491.11 KIK52661.1 - 2e-25 88.4 4.7 2e-25 88.4 4.7 1.9 2 1 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.14 KIK52661.1 - 1.8 6.7 7.1 1.9 6.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein KDZ PF18758.1 KIK52663.1 - 6.8e-34 117.4 0.0 1.2e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK52663.1 - 7.5e-19 67.9 2.4 9.6e-12 45.0 0.9 2.6 1 1 1 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases Chromo PF00385.24 KIK52664.1 - 0.16 11.9 0.5 9 6.3 0.0 3.5 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain 2OG-FeII_Oxy_3 PF13640.6 KIK52665.1 - 0.00055 20.8 0.0 0.00084 20.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P22_AR_C PF10548.9 KIK52666.1 - 0.023 14.9 0.2 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain ALF PF03752.13 KIK52666.1 - 0.038 14.0 0.2 0.068 13.2 0.2 1.3 1 0 0 1 1 1 0 Short repeats of unknown function Cauli_VI PF01693.16 KIK52668.1 - 4.9e-07 30.0 0.1 1.4e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin SARG PF15385.6 KIK52668.1 - 0.12 11.5 0.5 0.16 11.2 0.5 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein p450 PF00067.22 KIK52671.1 - 9.7e-58 196.0 0.0 1.2e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIK52672.1 - 1e-06 28.5 1.4 2.4e-06 27.4 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK52672.1 - 0.00048 19.9 1.5 0.0023 17.8 1.5 2.3 1 0 0 1 1 1 1 F-box domain LRR_2 PF07723.13 KIK52672.1 - 0.02 15.5 2.0 0.63 10.8 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat F-box_5 PF18511.1 KIK52672.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box GPI-anchored PF10342.9 KIK52673.1 - 0.00038 21.2 0.0 0.0006 20.5 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CRAL_TRIO PF00650.20 KIK52674.1 - 0.085 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 CRAL/TRIO domain p450 PF00067.22 KIK52675.1 - 1.3e-59 202.2 0.0 1.6e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIK52676.1 - 1.5e-43 149.1 52.1 2.8e-43 148.2 51.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily STALD PF18185.1 KIK52676.1 - 0.21 10.9 0.0 0.43 9.9 0.0 1.5 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family LCE6A PF15858.5 KIK52676.1 - 0.26 12.0 0.5 0.58 10.9 0.5 1.5 1 0 0 1 1 1 0 Late cornified envelope protein 6A family RAP1 PF07218.11 KIK52676.1 - 0.59 8.4 3.7 0.78 7.9 3.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NADH_B2 PF14813.6 KIK52678.1 - 0.017 14.9 2.1 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF3262 PF11660.8 KIK52678.1 - 0.17 12.3 0.5 0.17 12.3 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) DUF5455 PF17537.2 KIK52678.1 - 0.28 11.6 2.3 0.44 11.0 2.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) Cyanate_lyase PF02560.14 KIK52679.1 - 6.1e-34 115.7 0.0 9.8e-34 115.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KIK52679.1 - 0.048 14.0 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Complex1_LYR_2 PF13233.6 KIK52680.1 - 3.4e-18 66.2 0.0 4.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KIK52680.1 - 4.9e-10 39.3 0.0 9.4e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-C2H2 PF00096.26 KIK52681.1 - 4.4e-09 36.3 8.9 9.3e-05 22.7 0.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK52681.1 - 3.1e-06 27.5 5.1 0.022 15.6 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIK52681.1 - 0.00073 19.7 2.1 0.00081 19.6 0.9 1.6 2 0 0 2 2 2 1 Aberrant zinc-finger Na_trans_assoc PF06512.13 KIK52681.1 - 0.087 13.1 10.5 0.088 13.1 8.7 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated RXT2_N PF08595.11 KIK52681.1 - 0.96 9.5 9.7 1.9 8.5 9.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Golgin_A5 PF09787.9 KIK52681.1 - 1 8.8 11.2 1.5 8.2 11.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DNA_pol_phi PF04931.13 KIK52681.1 - 7.2 4.6 18.5 9 4.3 18.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_1 PF00561.20 KIK52682.1 - 2.7e-16 60.0 0.0 7.3e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK52682.1 - 1.5e-13 51.8 0.0 2.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK52682.1 - 1.2e-05 24.7 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIK52682.1 - 5.8e-05 22.9 0.0 0.00043 20.1 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KIK52682.1 - 0.00014 22.1 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 KIK52682.1 - 0.0051 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 KIK52682.1 - 0.0066 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KIK52682.1 - 0.086 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase PF07224.11 KIK52682.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 KIK52682.1 - 0.19 11.4 0.6 1.8 8.1 0.4 2.1 1 1 0 2 2 2 0 Putative esterase Glyco_hydro_11 PF00457.17 KIK52683.1 - 1.2e-73 246.5 10.4 1.4e-73 246.3 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 AbiTii PF18864.1 KIK52684.1 - 0.025 14.7 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 AbiTii Osmo_CC PF08946.10 KIK52684.1 - 0.029 14.6 0.1 0.055 13.7 0.1 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil F-box-like PF12937.7 KIK52685.1 - 1.2e-05 25.2 0.0 4.8e-05 23.2 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK52686.1 - 0.00028 20.7 0.0 0.00065 19.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like 2_5_RNA_ligase2 PF13563.6 KIK52687.1 - 2.9e-25 88.9 0.1 8.6e-25 87.4 0.1 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 KIK52687.1 - 7.9e-16 58.6 0.2 2.7e-15 56.8 0.1 2.0 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 KIK52687.1 - 2.5e-12 46.3 0.0 4.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 KIK52687.1 - 6.4e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LigT_PEase PF02834.16 KIK52687.1 - 3.5e-08 33.5 0.0 3.4e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 LigT like Phosphoesterase NTP_transf_2 PF01909.23 KIK52687.1 - 6.2e-06 26.4 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KIK52687.1 - 0.0074 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain NACHT PF05729.12 KIK52688.1 - 5.3e-10 39.5 0.0 7.1e-09 35.8 0.0 2.7 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK52688.1 - 0.00016 22.1 0.0 0.00047 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK52688.1 - 0.002 18.5 0.0 0.071 13.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KIK52688.1 - 0.11 12.8 0.0 0.73 10.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK52688.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TniB PF05621.11 KIK52688.1 - 0.12 11.7 0.0 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Mucin PF01456.17 KIK52689.1 - 0.0056 16.7 3.6 0.0069 16.4 3.6 1.0 1 0 0 1 1 1 1 Mucin-like glycoprotein tRNA_bind_2 PF13725.6 KIK52690.1 - 0.026 14.2 1.8 0.053 13.2 1.8 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain MULE PF10551.9 KIK52691.1 - 8.2e-11 42.2 0.0 2.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain CCP_MauG PF03150.14 KIK52691.1 - 0.17 12.5 0.7 0.37 11.4 0.7 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase DnaJ_CXXCXGXG PF00684.19 KIK52691.1 - 0.26 11.7 1.2 0.69 10.3 1.2 1.7 1 0 0 1 1 1 0 DnaJ central domain HNH_2 PF13391.6 KIK52692.1 - 0.00065 19.8 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.22 KIK52693.1 - 8.6e-36 123.7 0.0 2e-35 122.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF983 PF06170.12 KIK52694.1 - 0.14 12.5 0.2 0.18 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) p450 PF00067.22 KIK52695.1 - 1.9e-37 129.1 0.3 5.5e-18 65.0 0.0 4.1 4 0 0 4 4 4 4 Cytochrome P450 HpcH_HpaI PF03328.14 KIK52695.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HNH_2 PF13391.6 KIK52697.1 - 0.0073 16.4 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Pkinase_fungal PF17667.1 KIK52698.1 - 5.7e-15 55.0 0.1 6.2e-15 54.9 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase SLAC1 PF03595.17 KIK52699.1 - 1.9e-56 191.7 47.7 2.1e-56 191.5 47.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel F-box-like PF12937.7 KIK52700.1 - 5.2e-06 26.2 1.5 1.7e-05 24.6 1.5 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK52701.1 - 8.8e-09 35.1 0.5 2.6e-08 33.6 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK52701.1 - 0.18 11.7 3.1 12 5.9 0.1 2.9 2 0 0 2 2 2 0 F-box domain CCDC106 PF15794.5 KIK52703.1 - 7.5 6.2 14.9 0.41 10.3 8.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DDE_3 PF13358.6 KIK52706.1 - 0.00044 20.0 0.1 0.00045 20.0 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease AbiH PF14253.6 KIK52706.1 - 0.058 13.3 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF4937 PF16291.5 KIK52708.1 - 0.21 11.8 0.1 2.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 DUF3040 PF11239.8 KIK52708.1 - 0.56 10.5 6.2 1.5 9.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Response_reg PF00072.24 KIK52709.1 - 1.4e-24 86.4 0.2 2.6e-24 85.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF3450 PF11932.8 KIK52709.1 - 0.033 13.5 1.1 0.085 12.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 KIK52709.1 - 0.036 13.6 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 PspA/IM30 family CENP-F_leu_zip PF10473.9 KIK52709.1 - 0.08 13.0 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KIK52711.1 - 1.5 8.6 4.8 8.5 6.2 1.5 2.5 1 1 1 2 2 2 0 Septum formation initiator Vps51 PF08700.11 KIK52711.1 - 1.8 8.7 8.3 77 3.5 8.3 3.0 1 1 0 1 1 1 0 Vps51/Vps67 F-box-like PF12937.7 KIK52712.1 - 0.0019 18.0 0.7 0.0019 18.0 0.7 2.7 3 0 0 3 3 3 1 F-box-like HAP1_N PF04849.13 KIK52714.1 - 0.0023 17.2 0.1 0.0028 16.9 0.1 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF5106 PF17127.4 KIK52715.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Peptidase_C7 PF01830.18 KIK52715.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.0 1 0 0 1 1 1 0 Peptidase C7 family Alpha_kinase PF02816.18 KIK52716.1 - 2e-11 44.4 0.1 2.3e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family Tna_leader PF08053.11 KIK52717.1 - 0.041 13.8 0.4 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 Tryptophanase operon leader peptide DUF5082 PF16888.5 KIK52720.1 - 0.036 14.4 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GP57 PF17594.2 KIK52721.1 - 0.1 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 HCV_NS2 PF01538.18 KIK52722.1 - 0.055 13.1 2.0 0.23 11.1 0.2 2.2 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS2 DUF2678 PF10856.8 KIK52722.1 - 0.38 10.7 5.1 0.12 12.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Abhydrolase_6 PF12697.7 KIK52723.1 - 2e-13 51.5 0.2 2.5e-13 51.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK52723.1 - 6.6e-10 38.7 0.0 6.9e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK52723.1 - 1.3e-09 38.1 0.0 9.6e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIK52723.1 - 0.00045 20.0 0.0 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIK52723.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.5 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_23 PF13489.6 KIK52724.1 - 4.9e-17 62.2 0.0 7.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK52724.1 - 3e-14 53.5 0.0 9.6e-14 51.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK52724.1 - 1.2e-13 51.5 0.0 2.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK52724.1 - 3.9e-13 49.5 0.0 4.5e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK52724.1 - 5.4e-10 39.9 0.0 2.3e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIK52724.1 - 0.00026 20.8 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 KIK52724.1 - 0.00046 19.7 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KIK52724.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIK52724.1 - 0.0055 16.0 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KIK52724.1 - 0.0066 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIK52724.1 - 0.02 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIK52724.1 - 0.12 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.16 KIK52724.1 - 0.25 9.8 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase KDZ PF18758.1 KIK52725.1 - 1.7e-08 34.3 0.0 1.9e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK52726.1 - 3.4e-23 81.9 0.3 3.8e-23 81.7 0.3 1.0 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK52726.1 - 0.06 13.2 0.3 0.065 13.1 0.3 1.1 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases F-box-like PF12937.7 KIK52728.1 - 1.9e-10 40.5 1.0 3.4e-10 39.7 1.0 1.5 1 0 0 1 1 1 1 F-box-like IR1-M PF12185.8 KIK52728.1 - 0.061 13.3 0.1 0.56 10.2 0.1 2.1 1 1 1 2 2 2 0 Nup358/RanBP2 E3 ligase domain GAS PF13851.6 KIK52728.1 - 0.065 12.6 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding F-box PF00646.33 KIK52728.1 - 0.12 12.3 4.0 0.92 9.5 2.7 2.8 1 1 1 2 2 2 0 F-box domain FliD_N PF02465.18 KIK52728.1 - 0.18 12.5 0.0 0.25 12.1 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DPPIV_N PF00930.21 KIK52730.1 - 0.077 11.7 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SWIM PF04434.17 KIK52731.1 - 0.002 17.8 1.6 0.0038 16.9 1.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 KIK52731.1 - 0.0021 18.4 7.8 0.0021 18.4 7.8 2.5 2 1 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 KIK52731.1 - 0.0071 16.4 1.5 0.0071 16.4 1.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KIK52731.1 - 0.019 14.9 8.5 0.043 13.7 8.5 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KIK52731.1 - 0.14 12.3 9.3 0.23 11.7 6.6 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain Ish1 PF10281.9 KIK52733.1 - 2.7e-50 168.4 24.4 8.9e-10 38.7 1.0 6.8 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KIK52733.1 - 0.1 12.3 1.9 1.5e+02 2.2 0.1 4.9 5 0 0 5 5 5 0 HeH/LEM domain TryThrA_C PF12319.8 KIK52733.1 - 8.7 5.8 22.0 2.4 7.6 4.6 3.3 3 1 1 4 4 4 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Phi29_Phage_SSB PF17427.2 KIK52734.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein DUF2973 PF11189.8 KIK52734.1 - 0.24 11.5 2.9 20 5.4 2.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) zf-MYND PF01753.18 KIK52735.1 - 5.1e-06 26.5 14.1 5.1e-06 26.5 14.1 1.8 2 0 0 2 2 2 1 MYND finger TRIC PF05197.13 KIK52735.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 TRIC channel PhoR PF11808.8 KIK52735.1 - 0.11 12.9 0.2 0.34 11.4 0.2 1.8 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR zf-C6H2 PF15801.5 KIK52735.1 - 0.4 11.0 13.7 0.84 10.0 13.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_1 PF00515.28 KIK52736.1 - 1.4e-14 53.2 0.8 5.3e-06 26.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK52736.1 - 1.4e-12 46.7 0.5 3.3e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK52736.1 - 6e-10 38.5 0.3 0.0049 17.0 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK52736.1 - 5.7e-07 29.7 2.0 0.0021 18.3 0.5 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK52736.1 - 1.4e-06 28.8 0.1 3.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK52736.1 - 1.9e-06 27.5 0.9 1e-05 25.1 0.1 2.5 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KIK52736.1 - 3.2e-05 24.0 0.0 0.1 12.8 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK52736.1 - 3.4e-05 23.9 0.5 0.0017 18.6 0.2 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK52736.1 - 4.3e-05 23.9 0.1 0.23 12.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK52736.1 - 0.0013 18.6 0.2 0.014 15.4 0.2 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK52736.1 - 0.0014 19.3 0.0 8.7 7.5 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK52736.1 - 0.0075 16.5 0.2 0.72 10.1 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK52736.1 - 0.013 16.0 0.2 3.9 8.0 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 KIK52736.1 - 0.019 15.0 0.0 0.049 13.7 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KIK52737.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK52737.1 - 0.005 17.4 0.0 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Amidase PF01425.21 KIK52738.1 - 1.6e-76 258.1 0.0 3e-76 257.2 0.0 1.5 1 1 0 1 1 1 1 Amidase DUF2633 PF11119.8 KIK52742.1 - 0.44 10.5 0.2 0.44 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) CRCB PF02537.15 KIK52745.1 - 0.94 9.8 6.6 1.4 9.3 3.9 2.4 2 1 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Tup_N PF08581.10 KIK52746.1 - 0.024 14.9 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 Tup N-terminal DoxX_2 PF13564.6 KIK52750.1 - 0.056 13.6 4.1 0.15 12.2 4.2 1.8 1 1 0 1 1 1 0 DoxX-like family VKG_Carbox PF05090.14 KIK52750.1 - 0.11 11.3 1.0 0.12 11.2 0.4 1.3 1 1 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase SPX PF03105.19 KIK52751.1 - 0.5 10.2 4.0 1.3 8.9 4.0 1.7 1 1 0 1 1 1 0 SPX domain Helitron_like_N PF14214.6 KIK52757.1 - 1.2e-16 61.5 0.0 1.3e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK52760.1 - 1.1e-16 61.0 0.1 1.3e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK52760.1 - 7.5e-12 45.4 0.0 9.4e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK52760.1 - 4e-08 33.7 0.0 6.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK52760.1 - 0.0062 16.9 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KIK52760.1 - 0.046 12.7 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KIK52760.1 - 0.095 11.9 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 KIK52760.1 - 0.17 11.9 0.2 0.48 10.4 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF5623 PF18536.1 KIK52761.1 - 0.0058 16.9 0.0 0.071 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5623) Glyco_hydro_72 PF03198.14 KIK52761.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase KptA_kDCL PF18176.1 KIK52766.1 - 0.11 12.3 1.6 13 5.7 0.2 2.1 1 1 1 2 2 2 0 KptA in kinetoplastid DICER domain HR1 PF02185.16 KIK52771.1 - 7.1 6.8 8.4 1.1 9.4 2.3 2.2 2 0 0 2 2 2 0 Hr1 repeat Spc29 PF17082.5 KIK52772.1 - 0.0033 17.3 8.0 0.013 15.4 1.6 2.1 1 1 1 2 2 2 1 Spindle Pole Component 29 KASH_CCD PF14662.6 KIK52772.1 - 0.0042 17.0 13.6 0.0068 16.2 13.6 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Peptidase_S49_N PF08496.10 KIK52772.1 - 0.0045 17.1 1.1 0.0045 17.1 1.1 1.8 1 1 1 2 2 2 1 Peptidase family S49 N-terminal FAM76 PF16046.5 KIK52772.1 - 0.0048 16.3 5.0 0.0056 16.1 5.0 1.2 1 0 0 1 1 1 1 FAM76 protein Fez1 PF06818.15 KIK52772.1 - 0.0051 17.3 13.9 0.012 16.1 14.0 1.4 1 1 0 1 1 1 1 Fez1 Csm1_N PF18504.1 KIK52772.1 - 0.0079 16.5 16.6 0.11 12.8 5.2 3.8 1 1 3 4 4 4 1 Csm1 N-terminal domain Spc7 PF08317.11 KIK52772.1 - 0.01 14.8 13.5 0.014 14.3 13.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KIK52772.1 - 0.015 15.9 7.0 1 10.1 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA LRS4 PF10422.9 KIK52772.1 - 0.015 14.9 8.2 0.019 14.5 8.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 APG6_N PF17675.1 KIK52772.1 - 0.021 15.3 6.8 0.021 15.3 6.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Ribosomal_L10 PF00466.20 KIK52772.1 - 0.053 13.7 0.3 0.26 11.4 0.3 2.2 1 1 0 1 1 1 0 Ribosomal protein L10 DUF3450 PF11932.8 KIK52772.1 - 0.081 12.2 12.8 0.027 13.8 2.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 KIK52772.1 - 0.14 10.0 5.7 0.17 9.8 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KIK52772.1 - 0.16 11.6 6.4 0.19 11.3 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Spc34 PF08657.10 KIK52772.1 - 0.31 10.8 8.8 0.29 10.9 7.5 1.5 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF4407 PF14362.6 KIK52772.1 - 0.49 9.7 7.8 0.67 9.2 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KIK52772.1 - 0.62 10.7 10.6 2.1 9.0 2.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PEP-utilisers_N PF05524.13 KIK52772.1 - 0.66 10.2 9.0 4.6 7.4 9.0 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal ATG16 PF08614.11 KIK52772.1 - 0.7 10.1 21.5 1.4 9.1 7.5 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KIK52772.1 - 0.71 10.0 18.4 0.54 10.3 4.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KIK52772.1 - 1 9.7 14.6 1.3 9.3 1.9 2.9 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Spc42p PF11544.8 KIK52772.1 - 1.3 9.1 8.1 1.8 8.6 0.1 3.5 1 1 2 4 4 4 0 Spindle pole body component Spc42p HMMR_C PF15908.5 KIK52772.1 - 1.3 9.2 10.8 0.9 9.8 2.6 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Med9 PF07544.13 KIK52772.1 - 1.5 9.0 11.7 0.61 10.2 2.2 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ZapB PF06005.12 KIK52772.1 - 1.9 9.0 19.0 1.1 9.7 9.6 2.5 1 1 1 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 KIK52772.1 - 2.3 8.3 16.0 0.7 10.0 3.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Occludin_ELL PF07303.13 KIK52772.1 - 2.6 8.8 7.6 5.7 7.7 6.0 2.3 2 1 1 3 3 2 0 Occludin homology domain MRP-S26 PF14943.6 KIK52772.1 - 4 7.3 10.4 5.9 6.8 10.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 CENP-H PF05837.12 KIK52772.1 - 5 7.6 15.1 52 4.3 15.1 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Iron_permease PF04120.12 KIK52772.1 - 5.5 6.8 6.8 19 5.1 0.3 2.2 2 0 0 2 2 2 0 Low affinity iron permease Sec2p PF06428.11 KIK52772.1 - 6.1 6.9 17.5 0.3 11.1 3.6 3.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.8 KIK52772.1 - 6.9 6.7 22.3 4.9 7.2 10.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KIK52772.1 - 7.5 6.3 13.0 2.6 7.9 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KIK52772.1 - 7.7 6.6 6.0 9.7 6.2 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KIK52772.1 - 7.9 5.5 13.7 11 5.0 13.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fungal_TACC PF12709.7 KIK52772.1 - 8.3 6.9 14.6 2.4 8.6 1.1 2.9 2 2 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins USP8_interact PF08941.10 KIK52772.1 - 8.7 6.1 6.6 16 5.3 1.0 2.3 1 1 0 2 2 2 0 USP8 interacting C2-set_2 PF08205.12 KIK52773.1 - 1.4 9.1 6.2 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Plavaka PF18759.1 KIK52775.1 - 1.3e-41 142.9 0.0 1.5e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase YPEB PF14620.6 KIK52776.1 - 0.064 12.6 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 YpeB sporulation gag-asp_proteas PF13975.6 KIK52779.1 - 2.4e-05 24.8 0.0 3.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK52779.1 - 5.2e-05 23.8 0.0 0.00015 22.3 0.0 1.6 1 1 1 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KIK52779.1 - 0.0012 18.6 0.1 0.0025 17.6 0.1 1.6 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KIK52780.1 - 0.00019 21.4 0.8 0.0003 20.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KIK52780.1 - 0.018 14.7 0.7 0.028 14.1 0.7 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KIK52780.1 - 0.057 13.3 1.0 0.098 12.5 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle Cuticle_1 PF08140.11 KIK52780.1 - 0.059 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Acetyltransf_7 PF13508.7 KIK52783.1 - 4.1e-07 30.3 0.0 7.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK52783.1 - 4e-05 23.8 0.0 6.4e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIK52783.1 - 0.00013 22.0 0.0 0.00078 19.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK52783.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK52783.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 KIK52783.1 - 0.036 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MRVI1 PF05781.12 KIK52783.1 - 0.29 9.8 0.2 0.39 9.3 0.2 1.1 1 0 0 1 1 1 0 MRVI1 protein DUF3328 PF11807.8 KIK52784.1 - 5.9e-18 65.5 0.1 7.4e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KIK52785.1 - 4.6e-13 49.5 2.9 1.5e-12 47.8 2.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SRRM_C PF15230.6 KIK52786.1 - 6.3e-07 29.9 0.2 1.3e+02 3.2 0.0 8.6 1 1 10 11 11 11 3 Serine/arginine repetitive matrix protein C-terminus DUF2427 PF10348.9 KIK52787.1 - 0.53 10.1 5.7 0.17 11.6 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4763 PF15960.5 KIK52789.1 - 0.11 11.8 2.4 0.16 11.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Trypan_PARP PF05887.11 KIK52789.1 - 0.15 12.0 6.4 0.28 11.2 6.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.10 KIK52789.1 - 0.2 11.0 16.4 0.28 10.5 16.4 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 KIK52789.1 - 4.7 6.8 9.9 7.1 6.2 9.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TFIIF_alpha PF05793.12 KIK52789.1 - 8 4.9 17.2 11 4.4 17.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pyr_redox_3 PF13738.6 KIK52790.1 - 3e-22 79.3 0.0 1.3e-20 73.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK52790.1 - 2.7e-20 72.3 0.0 3.8e-19 68.5 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK52790.1 - 1.7e-18 66.8 0.0 6.4e-14 51.9 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK52790.1 - 1.1e-12 47.8 0.0 3.7e-10 39.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK52790.1 - 1.1e-06 28.7 0.1 0.053 13.8 0.0 3.3 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK52790.1 - 2.2e-06 28.1 0.1 0.003 18.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIK52790.1 - 4.9e-06 26.0 0.1 0.074 12.4 0.0 2.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KIK52790.1 - 5.8e-06 25.6 0.0 0.41 9.6 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 KIK52790.1 - 9.1e-06 24.6 0.0 1.1 7.9 0.0 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 KIK52790.1 - 1.8e-05 24.2 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KIK52790.1 - 3.4e-05 23.1 0.3 0.014 14.5 0.0 3.2 3 0 0 3 3 3 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 KIK52790.1 - 4.9e-05 23.4 0.0 0.0019 18.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KIK52790.1 - 8.8e-05 22.5 0.1 0.00065 19.6 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KIK52790.1 - 0.00025 20.4 0.0 0.35 10.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_7 PF13241.6 KIK52790.1 - 0.0014 19.0 0.1 0.024 15.1 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK52790.1 - 0.0017 17.7 0.1 0.035 13.4 0.1 2.3 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KIK52790.1 - 0.0026 17.4 0.0 0.13 11.9 0.1 2.8 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KIK52790.1 - 0.0036 16.9 0.1 3.3 7.2 0.1 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK52790.1 - 0.0041 17.1 0.6 3.9 7.4 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding IlvN PF07991.12 KIK52790.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KIK52790.1 - 0.02 15.1 0.0 5.2 7.4 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 KIK52790.1 - 0.033 14.8 0.2 0.25 11.9 0.0 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF1731 PF08338.11 KIK52790.1 - 0.034 14.0 0.0 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) NAD_Gly3P_dh_N PF01210.23 KIK52790.1 - 0.035 14.1 0.3 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Malic_M PF03949.15 KIK52790.1 - 0.036 13.3 0.1 0.22 10.8 0.0 2.2 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain NAD_binding_2 PF03446.15 KIK52790.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.24 KIK52790.1 - 0.069 12.2 1.0 5.7 5.9 0.2 2.5 2 1 0 2 2 2 0 FAD binding domain ThiF PF00899.21 KIK52790.1 - 0.11 11.8 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 ThiF family DUF2686 PF10887.8 KIK52790.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) DUF498 PF04430.14 KIK52790.1 - 0.13 12.3 0.0 6.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) But2 PF09792.9 KIK52791.1 - 0.00038 20.9 0.0 0.00055 20.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain p450 PF00067.22 KIK52792.1 - 7.1e-68 229.4 0.0 8.6e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PCDO_beta_N PF12391.8 KIK52792.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal AA_permease_2 PF13520.6 KIK52793.1 - 1.1e-58 199.2 61.8 1.3e-58 198.9 61.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK52793.1 - 1.2e-08 34.1 54.7 1.6e-08 33.6 54.7 1.1 1 0 0 1 1 1 1 Amino acid permease Fib_alpha PF08702.10 KIK52797.1 - 0.14 12.4 6.4 3.1 8.0 1.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KIK52797.1 - 0.15 12.4 7.6 1.7 9.0 1.2 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 KIK52797.1 - 0.57 9.7 4.9 0.8 9.2 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS6_N PF14661.6 KIK52797.1 - 1.1 8.8 5.9 2.2 7.8 5.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2570 PF10828.8 KIK52797.1 - 7.8 6.4 7.7 5.1 7.0 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) TPR_MLP1_2 PF07926.12 KIK52801.1 - 0.0011 19.0 10.3 0.023 14.8 3.3 2.2 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KIK52801.1 - 0.0025 18.3 3.9 0.0088 16.5 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 Rx_N PF18052.1 KIK52801.1 - 0.0039 17.4 3.4 0.013 15.7 0.5 2.2 2 0 0 2 2 2 1 Rx N-terminal domain SF-assemblin PF06705.11 KIK52801.1 - 0.0057 16.0 2.2 0.0057 16.0 2.2 2.0 2 0 0 2 2 2 1 SF-assemblin/beta giardin GIT_CC PF16559.5 KIK52801.1 - 0.0064 16.3 0.4 0.7 9.8 0.0 2.7 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor Seryl_tRNA_N PF02403.22 KIK52801.1 - 0.0086 16.3 7.2 0.49 10.7 1.7 2.4 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain TBCA PF02970.16 KIK52801.1 - 0.015 15.6 11.9 0.033 14.5 6.9 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A Golgin_A5 PF09787.9 KIK52801.1 - 0.02 14.4 12.9 0.26 10.7 0.8 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3479 PF11965.8 KIK52801.1 - 0.021 15.0 0.1 0.05 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) DUF948 PF06103.11 KIK52801.1 - 0.022 15.0 1.9 0.072 13.4 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CortBP2 PF09727.9 KIK52801.1 - 0.027 14.4 3.3 0.027 14.4 3.3 2.3 2 0 0 2 2 2 0 Cortactin-binding protein-2 Ax_dynein_light PF10211.9 KIK52801.1 - 0.036 14.0 9.3 0.14 12.1 2.8 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain OmpH PF03938.14 KIK52801.1 - 0.037 14.4 6.6 0.1 12.9 3.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 KIK52801.1 - 0.05 14.1 12.5 2.3 8.7 0.3 2.5 2 0 0 2 2 2 0 Cell division protein ZapB VirE2 PF07229.12 KIK52801.1 - 0.061 12.0 1.4 0.47 9.0 0.3 1.9 1 1 1 2 2 2 0 VirE2 FlxA PF14282.6 KIK52801.1 - 0.088 12.8 10.2 3 7.9 6.1 2.3 2 0 0 2 2 2 0 FlxA-like protein PH_BEACH PF14844.6 KIK52801.1 - 0.13 12.3 2.1 0.16 12.1 0.6 1.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH Lzipper-MIP1 PF14389.6 KIK52801.1 - 0.17 12.2 7.8 1.9 8.9 0.3 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 LMBR1 PF04791.16 KIK52801.1 - 0.21 10.5 2.5 0.27 10.1 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ABC_tran_CTD PF16326.5 KIK52801.1 - 0.27 11.5 12.2 4.7 7.5 4.6 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain AAA_13 PF13166.6 KIK52801.1 - 0.28 9.8 11.6 0.43 9.2 10.6 1.5 1 1 1 2 2 2 0 AAA domain DivIC PF04977.15 KIK52801.1 - 0.32 10.8 10.2 0.3 10.9 0.3 2.6 2 1 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 KIK52801.1 - 0.44 10.7 11.7 2.4 8.4 0.7 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FapA PF03961.13 KIK52801.1 - 0.75 8.3 11.4 3 6.4 4.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Csm1_N PF18504.1 KIK52801.1 - 0.83 10.0 9.0 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF1192 PF06698.11 KIK52801.1 - 0.89 9.7 9.5 6.6 6.9 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4200 PF13863.6 KIK52801.1 - 1.1 9.6 15.6 1.4 9.4 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4094 PF13334.6 KIK52801.1 - 1.2 9.6 9.0 1.6 9.2 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 KIK52801.1 - 2 8.8 8.6 7.5 6.9 0.1 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family Spc24 PF08286.11 KIK52801.1 - 2.6 8.3 13.0 4 7.7 0.2 2.6 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4337 PF14235.6 KIK52801.1 - 2.6 8.1 7.2 3.5 7.7 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) NPL PF17800.1 KIK52802.1 - 1.2e-08 35.5 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin-like domain Peptidase_C48 PF02902.19 KIK52808.1 - 2.4e-05 24.3 0.0 0.14 12.0 0.0 2.4 1 1 1 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 KIK52812.1 - 0.036 14.9 3.9 0.069 14.1 0.0 3.3 5 0 0 5 5 5 0 WD domain, G-beta repeat F-box-like PF12937.7 KIK52814.1 - 1.8e-05 24.5 1.5 4.7e-05 23.2 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK52814.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.4 2 0 0 2 2 2 0 F-box domain DUF648 PF04890.13 KIK52816.1 - 0.065 13.0 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF745 PF05335.13 KIK52816.1 - 0.16 11.7 5.3 2.4 7.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK52816.1 - 4 7.4 8.3 3.4 7.6 0.3 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 KIK52817.1 - 0.0048 16.4 0.4 0.0073 15.8 0.4 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KIK52817.1 - 0.0078 16.5 1.5 0.013 15.7 1.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Syntaphilin PF15290.6 KIK52817.1 - 0.024 14.3 1.8 0.045 13.4 1.8 1.4 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Spc7 PF08317.11 KIK52817.1 - 0.052 12.4 0.7 0.077 11.9 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KIK52817.1 - 0.11 12.3 1.1 0.17 11.7 0.4 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 Csm1_N PF18504.1 KIK52817.1 - 0.11 12.8 2.7 0.24 11.7 2.1 1.8 1 1 1 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KIK52817.1 - 0.16 12.0 4.6 0.29 11.2 4.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Casc1_N PF15927.5 KIK52817.1 - 0.66 9.6 4.5 1.1 8.9 4.5 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA-ATPase_like PF09820.9 KIK52818.1 - 3.5e-09 36.5 0.0 3e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Predicted AAA-ATPase P22_AR_C PF10548.9 KIK52818.1 - 0.18 12.0 0.1 2 8.7 0.1 2.3 3 0 0 3 3 3 0 P22AR C-terminal domain TPT PF03151.16 KIK52819.1 - 0.0033 16.8 0.1 0.005 16.2 0.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family mTERF PF02536.14 KIK52819.1 - 0.044 12.7 0.1 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 mTERF Seryl_tRNA_N PF02403.22 KIK52820.1 - 1.2 9.4 13.4 0.14 12.4 8.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Peptidase_C48 PF02902.19 KIK52822.1 - 3.4e-05 23.8 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Gp-FAR-1 PF05823.12 KIK52822.1 - 4e-05 24.0 2.6 4e-05 24.0 2.6 1.8 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3450 PF11932.8 KIK52822.1 - 0.0011 18.3 5.6 0.0016 17.8 5.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KIK52822.1 - 0.0023 17.4 4.5 0.0031 16.9 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Lebercilin PF15619.6 KIK52822.1 - 0.0029 17.3 10.1 0.0093 15.6 6.0 2.1 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease OmpH PF03938.14 KIK52822.1 - 0.0036 17.7 6.0 0.0036 17.7 6.0 2.2 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.7 KIK52822.1 - 0.0055 16.9 14.3 0.071 13.3 6.3 2.3 1 1 1 2 2 2 2 Tropomyosin like TMF_DNA_bd PF12329.8 KIK52822.1 - 0.0055 16.7 11.2 0.0055 16.7 11.2 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Filament PF00038.21 KIK52822.1 - 0.007 16.0 9.8 0.016 14.8 9.2 1.5 1 1 0 1 1 1 1 Intermediate filament protein SHE3 PF17078.5 KIK52822.1 - 0.011 15.5 9.3 0.017 14.8 9.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ACCA PF03255.14 KIK52822.1 - 0.013 15.3 6.9 0.11 12.4 1.5 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MeMO_Hyd_G PF02964.16 KIK52822.1 - 0.024 14.6 0.2 0.039 14.0 0.2 1.3 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain PKcGMP_CC PF16808.5 KIK52822.1 - 0.025 14.5 2.6 0.025 14.5 2.6 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4618 PF15397.6 KIK52822.1 - 0.05 13.0 9.5 0.18 11.2 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF5600 PF18150.1 KIK52822.1 - 0.12 13.0 1.1 0.65 10.6 0.6 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5600) DUF4164 PF13747.6 KIK52822.1 - 0.14 12.4 9.1 0.43 10.9 3.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HMMR_N PF15905.5 KIK52822.1 - 0.15 11.5 12.8 0.03 13.8 6.6 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FliD_C PF07195.12 KIK52822.1 - 0.15 11.5 6.8 0.17 11.3 2.2 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Exonuc_VII_L PF02601.15 KIK52822.1 - 0.19 11.3 3.5 0.28 10.7 3.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pox_A_type_inc PF04508.12 KIK52822.1 - 0.33 10.9 7.7 8.2 6.5 0.1 4.3 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.12 KIK52822.1 - 0.33 11.0 13.8 0.25 11.4 7.0 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 KIK52822.1 - 0.35 9.7 2.4 0.42 9.5 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ING PF12998.7 KIK52822.1 - 0.47 11.1 8.7 0.56 10.8 3.9 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Bacillus_HBL PF05791.11 KIK52822.1 - 0.48 10.2 7.8 0.16 11.8 3.7 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tup_N PF08581.10 KIK52822.1 - 0.49 10.7 12.8 2.8 8.3 5.6 2.8 2 1 1 3 3 3 0 Tup N-terminal DUF724 PF05266.14 KIK52822.1 - 0.55 10.0 6.1 0.19 11.6 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 KIK52822.1 - 0.59 10.1 13.9 0.73 9.8 6.1 2.7 2 2 0 2 2 2 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KIK52822.1 - 0.73 10.1 14.1 3.5 8.0 0.3 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain DASH_Spc19 PF08287.11 KIK52822.1 - 0.84 9.5 10.6 0.29 11.0 0.3 2.4 2 1 0 2 2 2 0 Spc19 Baculo_PEP_C PF04513.12 KIK52822.1 - 1.1 9.2 11.9 2.8 8.0 2.4 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugarporin_N PF11471.8 KIK52822.1 - 1.3 9.0 4.3 1.9 8.5 2.4 2.2 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Sec2p PF06428.11 KIK52822.1 - 1.4 9.0 15.3 0.2 11.6 1.5 3.1 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p HIP1_clath_bdg PF16515.5 KIK52822.1 - 1.5 9.5 10.6 1.1 9.9 6.4 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2730 PF10805.8 KIK52822.1 - 1.6 8.9 5.3 0.7 10.0 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF16 PF01519.16 KIK52822.1 - 1.7 9.2 9.8 0.85 10.1 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 PRKG1_interact PF15898.5 KIK52822.1 - 1.7 9.6 11.3 3.6 8.5 3.7 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain IFP_35_N PF07334.13 KIK52822.1 - 1.8 8.7 7.4 0.53 10.4 1.9 2.5 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Wtap PF17098.5 KIK52822.1 - 1.8 8.5 9.7 3.3 7.6 5.0 2.8 1 1 1 2 2 2 0 WTAP/Mum2p family DUF4140 PF13600.6 KIK52822.1 - 1.9 9.0 7.3 2.4 8.7 3.2 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KIK52822.1 - 2 8.5 9.4 9.6 6.3 3.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Sipho_Gp157 PF05565.11 KIK52822.1 - 2.9 7.9 10.9 1.1 9.2 6.6 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 TEX13 PF15186.6 KIK52822.1 - 3.5 7.3 7.5 17 5.0 0.1 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family YabA PF06156.13 KIK52822.1 - 3.7 8.2 11.8 2 9.1 5.5 2.6 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 KIK52822.1 - 4 7.5 17.4 30 4.6 15.2 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KIK52822.1 - 4.2 6.2 14.0 1.2 7.9 8.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein KfrA_N PF11740.8 KIK52822.1 - 4.4 8.0 7.0 11 6.7 3.1 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Tweety PF04906.13 KIK52822.1 - 4.5 5.8 7.3 1.8 7.1 2.5 2.0 1 1 1 2 2 2 0 Tweety Cnn_1N PF07989.11 KIK52822.1 - 4.9 7.4 12.5 0.52 10.5 4.0 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 PspA_IM30 PF04012.12 KIK52822.1 - 5.4 6.5 13.9 31 4.0 6.4 2.4 1 1 1 2 2 2 0 PspA/IM30 family DivIC PF04977.15 KIK52822.1 - 6.8 6.5 12.6 12 5.7 3.1 3.2 2 1 1 3 3 3 0 Septum formation initiator Spc24 PF08286.11 KIK52822.1 - 7.3 6.9 11.3 0.51 10.6 2.8 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF1043 PF06295.12 KIK52822.1 - 7.5 6.6 12.7 6.7 6.7 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) GrpE PF01025.19 KIK52822.1 - 8.4 6.0 10.7 45 3.7 10.4 2.1 1 1 0 1 1 1 0 GrpE FA_FANCE PF11510.8 KIK52823.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE His_Phos_2 PF00328.22 KIK52824.1 - 6e-47 160.8 0.0 7.4e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KIK52826.1 - 5.5e-45 154.3 0.0 6.8e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SKN1 PF03935.15 KIK52827.1 - 3.4e-07 29.0 0.0 4.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) cNMPbd_u2 PF16643.5 KIK52827.1 - 2.7 8.4 9.5 0.53 10.7 0.4 2.5 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein DLH PF01738.18 KIK52828.1 - 2.8e-25 89.1 0.0 3.3e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family OmdA PF13376.6 KIK52828.1 - 0.19 11.7 0.1 0.65 10.0 0.1 1.9 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated tRNA-synt_2 PF00152.20 KIK52831.1 - 1.9e-75 253.9 0.0 2.4e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK52831.1 - 9.9e-07 28.7 0.1 2.1e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIK52831.1 - 0.012 15.1 0.2 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ketoacyl-synt PF00109.26 KIK52832.1 - 1.8e-75 253.8 0.0 3e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK52832.1 - 4.5e-45 154.5 0.0 3.9e-43 148.2 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KIK52832.1 - 5.4e-36 123.2 0.1 9.8e-36 122.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KIK52832.1 - 1.1e-29 103.9 4.0 4.5e-26 92.1 1.1 2.7 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KIK52832.1 - 3.9e-19 68.8 2.0 8.6e-10 38.8 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KIK52832.1 - 5.5e-19 68.5 0.0 9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KIK52832.1 - 6.6e-17 62.4 0.0 4.9e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KIK52832.1 - 6.6e-07 30.2 1.3 4.5e-05 24.2 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KIK52832.1 - 1.3e-06 28.8 0.0 1.4e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KIK52832.1 - 0.00021 20.8 0.1 0.00044 19.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.8 KIK52832.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) zf-C2H2 PF00096.26 KIK52833.1 - 7.7e-10 38.7 10.8 6.3e-05 23.2 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK52833.1 - 2.5e-06 27.8 11.9 0.005 17.6 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK52833.1 - 3.8e-05 23.3 10.0 0.016 14.9 0.9 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KIK52833.1 - 0.00043 20.6 6.2 0.00043 20.6 6.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KIK52833.1 - 0.0033 17.8 3.0 0.04 14.3 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK52833.1 - 0.011 15.7 10.2 0.067 13.2 4.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK52833.1 - 0.02 15.2 3.3 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fer4_9 PF13187.6 KIK52833.1 - 0.084 13.0 4.0 0.2 11.9 4.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain p450 PF00067.22 KIK52835.1 - 7.9e-79 265.5 0.0 1.7e-78 264.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF155 PF02582.14 KIK52836.1 - 2.3e-48 164.6 0.1 4.6e-48 163.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KIK52836.1 - 0.15 12.5 0.5 1.3 9.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 His_Phos_1 PF00300.22 KIK52837.1 - 4.6e-36 124.3 0.0 1.5e-35 122.6 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acetyltransf_3 PF13302.7 KIK52838.1 - 3.9e-15 56.8 0.5 6.8e-15 56.0 0.5 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK52838.1 - 0.00014 22.1 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK52838.1 - 0.049 14.1 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 KIK52839.1 - 2.2e-59 201.4 0.0 3.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4791 PF16039.5 KIK52839.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) p450 PF00067.22 KIK52840.1 - 8.8e-59 199.4 0.0 1.2e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ESPR PF13018.6 KIK52840.1 - 0.00085 19.1 0.4 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Extended Signal Peptide of Type V secretion system DUF4791 PF16039.5 KIK52840.1 - 0.2 11.2 0.9 0.49 9.9 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4791) zf-C3HC4_3 PF13920.6 KIK52841.1 - 2.9e-11 43.1 5.2 2.2e-09 37.0 1.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK52841.1 - 0.00016 21.5 1.5 0.0006 19.6 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK52841.1 - 0.0012 18.7 4.3 0.0012 18.7 4.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK52841.1 - 0.0023 18.2 6.1 0.0047 17.2 1.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIK52841.1 - 0.0067 16.4 2.2 0.054 13.5 0.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK52841.1 - 1.7 8.7 7.6 11 6.1 0.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger RNA_pol_L_2 PF13656.6 KIK52842.1 - 2.8e-25 87.9 0.0 3.6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIK52842.1 - 6e-12 44.8 0.0 9.9e-12 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L27A PF00828.19 KIK52843.1 - 2.4e-21 76.8 0.0 3.5e-21 76.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 KIK52844.1 - 3e-67 226.8 0.0 7.8e-67 225.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK52844.1 - 4.1e-34 118.0 0.0 9.5e-34 116.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK52844.1 - 0.0001 22.3 0.0 0.00043 20.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family ComFB PF10719.9 KIK52846.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Late competence development protein ComFB VIR_N PF15912.5 KIK52846.1 - 2.3 7.8 7.8 9.3 5.8 0.2 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal MMR_HSR1 PF01926.23 KIK52847.1 - 2.8e-11 43.5 0.0 7.8e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK52847.1 - 0.00079 19.4 0.0 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KIK52847.1 - 0.0054 16.3 0.3 0.012 15.1 0.3 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KIK52847.1 - 0.0057 17.1 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK52847.1 - 0.017 15.6 0.6 0.043 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK52847.1 - 0.023 14.4 0.3 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KIK52847.1 - 0.03 13.4 0.4 0.089 11.9 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain Arf PF00025.21 KIK52847.1 - 0.057 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Herpes_UL47 PF03362.13 KIK52847.1 - 0.15 10.8 0.2 0.22 10.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein Dynamin_N PF00350.23 KIK52847.1 - 0.17 11.9 0.2 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KIK52847.1 - 0.69 9.6 4.0 4.3 7.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Oxidored_FMN PF00724.20 KIK52848.1 - 5e-74 249.6 0.0 5.9e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIK52848.1 - 0.0054 16.2 0.0 0.28 10.6 0.0 2.4 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel UDPGT PF00201.18 KIK52850.1 - 1.2e-18 67.2 0.0 1.8e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK52850.1 - 0.0036 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Xpo1 PF08389.12 KIK52851.1 - 1.7e-14 54.1 0.1 9.4e-11 42.0 0.0 4.8 4 2 0 5 5 5 1 Exportin 1-like protein Importin_rep PF18773.1 KIK52851.1 - 3.2e-08 33.1 0.4 9.3e-08 31.7 0.1 1.9 2 0 0 2 2 2 1 Importin 13 repeat Importin_rep_3 PF18806.1 KIK52851.1 - 3.4e-08 33.4 0.0 1.4e-07 31.5 0.0 2.2 1 0 0 1 1 1 1 Importin 13 repeat CRM1_C PF08767.11 KIK52851.1 - 0.0044 16.2 0.0 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 CRM1 C terminal Mistic PF11458.8 KIK52851.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Arm PF00514.23 KIK52851.1 - 0.27 11.3 2.0 19 5.5 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UDPGT PF00201.18 KIK52853.1 - 7.7e-17 61.3 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK52853.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KIK52855.1 - 6e-18 64.9 0.1 8.2e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK52855.1 - 0.0046 16.9 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KIK52857.1 - 4e-17 62.2 0.0 5.4e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KIK52859.1 - 1.4e-18 67.0 0.0 1.8e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK52859.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Methyltransf_16 PF10294.9 KIK52860.1 - 3.9e-06 26.7 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK52860.1 - 6.5e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK52860.1 - 0.00019 22.1 0.0 0.17 12.6 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KIK52860.1 - 0.0075 16.1 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KIK52860.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mem_trans PF03547.18 KIK52861.1 - 3.3e-20 71.9 5.6 1.5e-19 69.7 5.6 1.8 1 1 0 1 1 1 1 Membrane transport protein Zn_ribbon_17 PF17120.5 KIK52863.1 - 2.2e-09 36.8 13.5 2.2e-09 36.8 13.5 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIK52863.1 - 0.00022 22.0 11.7 0.00059 20.6 0.1 5.5 4 0 0 4 4 4 1 WD domain, G-beta repeat UDPGT PF00201.18 KIK52865.1 - 5.6e-17 61.7 0.1 7.6e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK52865.1 - 0.028 14.4 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Hamartin PF04388.12 KIK52867.1 - 0.038 12.7 4.1 0.038 12.7 4.1 1.0 1 0 0 1 1 1 0 Hamartin protein DUF3160 PF11369.8 KIK52867.1 - 0.13 10.7 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) CytochromB561_N PF09786.9 KIK52867.1 - 5.4 5.9 10.9 5 6.0 10.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal BTB PF00651.31 KIK52868.1 - 6e-05 23.2 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ProQ_C PF17516.2 KIK52870.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain F-box-like PF12937.7 KIK52871.1 - 0.0002 21.2 3.6 0.00022 21.0 0.8 2.6 2 1 1 3 3 3 1 F-box-like MYO10_CC PF16735.5 KIK52871.1 - 0.58 10.3 2.4 2 8.5 1.0 2.3 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain FOXP-CC PF16159.5 KIK52872.1 - 0.0021 18.6 0.3 0.0057 17.3 0.1 1.8 2 0 0 2 2 2 1 FOXP coiled-coil domain DUF1639 PF07797.14 KIK52872.1 - 0.084 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) zf-C2H2 PF00096.26 KIK52872.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type CCDC154 PF15450.6 KIK52873.1 - 0.0082 14.7 5.2 0.01 14.5 5.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 Leu_zip PF15294.6 KIK52873.1 - 0.022 14.3 4.6 0.028 14.0 4.6 1.2 1 0 0 1 1 1 0 Leucine zipper DUF3349 PF11829.8 KIK52873.1 - 0.089 13.6 0.9 0.22 12.3 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) HIP1_clath_bdg PF16515.5 KIK52873.1 - 0.39 11.4 8.1 0.49 11.0 7.2 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-H PF05837.12 KIK52873.1 - 0.41 11.1 6.4 0.23 11.9 2.5 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SlyX PF04102.12 KIK52873.1 - 0.98 10.1 6.4 0.54 10.9 1.5 2.3 1 1 1 2 2 2 0 SlyX F-box-like PF12937.7 KIK52874.1 - 0.0013 18.6 8.7 0.0026 17.6 6.6 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK52874.1 - 0.067 13.1 3.8 1.9 8.5 0.2 3.0 2 0 0 2 2 2 0 F-box domain DUF4203 PF13886.6 KIK52875.1 - 0.047 13.3 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) AIG1 PF04548.16 KIK52876.1 - 3.2e-10 39.7 0.2 7.5e-10 38.5 0.2 1.6 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KIK52876.1 - 1e-06 28.8 0.1 3e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK52876.1 - 0.00023 21.1 0.2 0.00068 19.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KIK52876.1 - 0.006 15.9 0.1 0.016 14.5 0.1 1.6 1 1 0 1 1 1 1 Septin IstB_IS21 PF01695.17 KIK52876.1 - 0.01 15.6 0.1 0.28 10.9 0.0 2.6 2 1 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KIK52876.1 - 0.014 15.5 3.8 1.6 8.8 0.0 3.5 1 1 1 3 3 3 0 Dynamin family Roc PF08477.13 KIK52876.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AFG1_ATPase PF03969.16 KIK52876.1 - 0.051 12.5 0.0 6.9 5.4 0.1 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_16 PF13191.6 KIK52876.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK52876.1 - 0.06 13.6 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 KIK52876.1 - 0.069 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 KIK52876.1 - 0.074 13.0 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 KIK52876.1 - 0.088 12.3 0.5 2.3 7.7 0.2 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 KIK52876.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK52876.1 - 0.26 11.8 2.8 0.36 11.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter PBP1_TM PF14812.6 KIK52876.1 - 0.44 11.0 4.6 0.68 10.3 1.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_23 PF13476.6 KIK52876.1 - 0.45 11.0 8.4 8.1 6.9 8.4 2.7 1 1 0 1 1 1 0 AAA domain Fer4 PF00037.27 KIK52876.1 - 0.91 9.4 4.5 0.49 10.3 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain MORN PF02493.20 KIK52877.1 - 1.3e-08 34.2 2.7 0.0036 17.1 0.1 3.0 3 0 0 3 3 3 2 MORN repeat MACPF PF01823.19 KIK52877.1 - 0.0079 16.3 1.0 0.02 15.0 1.0 1.7 1 1 0 1 1 1 1 MAC/Perforin domain AIG1 PF04548.16 KIK52878.1 - 1.6e-08 34.2 2.8 1.7e-08 34.1 0.4 2.2 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 KIK52878.1 - 3e-07 30.5 1.3 1.1e-06 28.7 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK52878.1 - 0.00029 20.8 0.0 0.00029 20.8 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KIK52878.1 - 0.018 15.3 0.3 0.11 12.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 KIK52878.1 - 0.019 14.3 0.1 0.049 12.9 0.1 1.7 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KIK52878.1 - 0.021 15.2 0.0 0.096 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Baculo_PEP_C PF04513.12 KIK52878.1 - 0.024 14.7 0.9 1.2 9.2 0.0 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 KIK52878.1 - 0.026 14.4 1.9 0.026 14.4 1.9 3.3 3 1 0 3 3 2 0 Phage minor structural protein GP20 Carbam_trans_N PF02543.15 KIK52878.1 - 0.035 13.8 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Roc PF08477.13 KIK52878.1 - 0.047 13.9 0.3 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF5082 PF16888.5 KIK52878.1 - 0.049 13.9 0.7 0.049 13.9 0.7 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 KIK52878.1 - 0.049 12.9 0.0 0.049 12.9 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) AAA PF00004.29 KIK52878.1 - 0.059 13.8 0.3 0.27 11.6 0.0 2.3 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) TPD52 PF04201.15 KIK52878.1 - 0.072 12.7 4.8 0.35 10.5 1.7 2.4 2 0 0 2 2 2 0 Tumour protein D52 family AAA_5 PF07728.14 KIK52878.1 - 0.079 13.0 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIK52878.1 - 0.089 12.2 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KIK52878.1 - 0.091 12.3 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KIK52878.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.4 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KIK52878.1 - 0.3 11.6 4.5 0.35 11.4 0.1 2.8 3 0 0 3 3 3 0 ABC transporter Dynamin_N PF00350.23 KIK52878.1 - 0.72 9.9 0.0 0.72 9.9 0.0 4.7 4 2 1 5 5 5 0 Dynamin family DUF948 PF06103.11 KIK52878.1 - 2.1 8.6 3.9 15 5.9 0.1 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 KIK52878.1 - 5.5 7.3 23.2 0.037 14.4 2.9 2.9 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 KIK52878.1 - 5.9 6.9 10.7 2.7 8.0 0.1 3.4 3 1 1 4 4 4 0 Laminin Domain II Kinesin PF00225.23 KIK52881.1 - 6.1e-92 308.1 0.0 1.3e-91 307.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK52881.1 - 3.9e-21 75.5 0.0 8.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TBCA PF02970.16 KIK52881.1 - 2.2 8.7 16.8 2.9 8.3 4.1 2.6 2 0 0 2 2 2 0 Tubulin binding cofactor A CxC2 PF18803.1 KIK52889.1 - 2.4e-09 37.3 0.4 3.3e-09 36.8 0.4 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CobW_C PF07683.14 KIK52891.1 - 0.035 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain YL1 PF05764.13 KIK52891.1 - 0.18 11.9 17.2 0.11 12.6 11.2 2.1 1 1 1 2 2 2 0 YL1 nuclear protein DEADboxA PF12343.8 KIK52894.1 - 0.066 13.7 0.4 0.099 13.2 0.4 1.2 1 0 0 1 1 1 0 Cold shock protein DEAD box A SMG1 PF15785.5 KIK52894.1 - 0.18 10.2 0.0 0.21 10.0 0.0 1.0 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Sec23_trunk PF04811.15 KIK52897.1 - 3.7e-08 33.2 0.0 5.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Ribosomal_L27_C PF18471.1 KIK52899.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain RRM_1 PF00076.22 KIK52901.1 - 2.6e-13 49.6 0.0 5.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIK52901.1 - 0.00036 21.0 1.0 0.0007 20.1 1.0 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 6PF2K PF01591.18 KIK52902.1 - 2.9e-63 213.1 0.0 7.4e-63 211.8 0.0 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIK52902.1 - 5.7e-25 88.1 0.0 8.4e-20 71.3 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIK52902.1 - 0.00016 21.8 0.1 0.0004 20.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KIK52902.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF816 PF05674.12 KIK52902.1 - 0.032 14.2 0.5 0.056 13.4 0.5 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Toprim_3 PF13362.6 KIK52902.1 - 0.14 12.6 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Toprim domain APS_kinase PF01583.20 KIK52902.1 - 0.16 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Transp_cyt_pur PF02133.15 KIK52903.1 - 6.8e-138 460.1 39.9 7.9e-138 459.9 39.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tim17 PF02466.19 KIK52903.1 - 0.076 13.4 0.1 0.076 13.4 0.1 2.4 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family GEMIN8 PF15348.6 KIK52904.1 - 0.0041 17.5 1.3 0.0051 17.2 1.3 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 DUF4100 PF13352.6 KIK52904.1 - 5 6.8 8.1 7.9 6.2 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Pkinase PF00069.25 KIK52905.1 - 1.3e-43 149.3 0.0 1.9e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK52905.1 - 4.3e-24 85.2 0.0 7.3e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK52905.1 - 2.9e-05 23.5 0.0 0.00035 20.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KIK52905.1 - 0.0043 17.0 0.1 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIK52905.1 - 0.043 12.8 0.6 0.093 11.7 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ribosomal_S5_C PF03719.15 KIK52906.1 - 4.9e-18 64.3 0.0 8e-17 60.5 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KIK52906.1 - 7e-16 58.0 0.2 1.3e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain HD_2 PF12917.7 KIK52907.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Pkinase PF00069.25 KIK52914.1 - 6.1e-05 22.5 0.0 7.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK52914.1 - 0.00051 19.7 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK52914.1 - 0.0023 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK52914.1 - 0.0059 16.6 0.2 1 9.2 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 KIK52914.1 - 0.026 14.1 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Tmemb_170 PF10190.9 KIK52915.1 - 3.7e-08 33.7 4.8 9.7e-06 25.9 2.1 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 MSP1a PF11670.8 KIK52915.1 - 0.003 16.9 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 Major surface protein 1a (MSP1a) MscS_TM PF12794.7 KIK52915.1 - 0.004 16.1 0.5 0.004 16.1 0.5 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 DUF4395 PF14340.6 KIK52915.1 - 0.01 16.1 0.6 0.035 14.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) TMEM208_SND2 PF05620.11 KIK52915.1 - 0.55 10.0 0.0 0.55 10.0 0.0 2.8 2 1 2 4 4 4 0 SRP-independent targeting protein 2/TMEM208 Las1 PF04031.13 KIK52917.1 - 0.0069 16.5 0.2 3.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Las1-like TMEM132 PF16070.5 KIK52917.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 132 MAGI_u5 PF16666.5 KIK52918.1 - 0.11 12.6 6.9 0.2 11.8 6.9 1.3 1 0 0 1 1 1 0 Unstructured region on MAGI Cauli_VI PF01693.16 KIK52919.1 - 7e-06 26.3 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin SecD_SecF PF02355.16 KIK52921.1 - 0.0032 16.9 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein export membrane protein CxC2 PF18803.1 KIK52922.1 - 2.7e-39 133.6 0.3 4.6e-39 132.9 0.3 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK52922.1 - 1.1e-07 31.9 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK52922.1 - 0.00023 21.2 3.4 0.00065 19.8 3.4 1.8 1 0 0 1 1 1 1 B-box zinc finger CxC3 PF18804.1 KIK52922.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 1.9 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases CEBP_ZZ PF16366.5 KIK52922.1 - 0.074 13.3 6.2 0.18 12.1 6.2 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2797 PF10977.8 KIK52922.1 - 2.4 8.0 5.0 3.4 7.5 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) KDZ PF18758.1 KIK52923.1 - 1.2e-46 159.1 0.2 1.5e-46 158.8 0.2 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RVT_1 PF00078.27 KIK52926.1 - 4.7e-07 29.6 0.0 9.4e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_35 PF14516.6 KIK52926.1 - 0.068 12.0 0.1 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain zf-RVT PF13966.6 KIK52927.1 - 0.012 16.3 1.6 0.012 16.3 1.6 2.6 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase ZZ PF00569.17 KIK52927.1 - 1.2 9.1 6.9 0.43 10.4 0.7 2.8 2 1 0 2 2 2 0 Zinc finger, ZZ type DLEU7 PF15760.5 KIK52928.1 - 0.25 10.8 1.6 5.6 6.4 0.1 3.0 2 2 2 4 4 4 0 Leukemia-associated protein 7 Glyco_hydro_18 PF00704.28 KIK52930.1 - 2.1e-09 37.6 0.2 1.5e-08 34.8 0.1 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KIK52933.1 - 2e-19 70.5 0.1 2.3e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KIK52934.1 - 2.3e-17 63.7 0.8 3.3e-17 63.2 0.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KIK52935.1 - 5.2e-17 62.5 1.9 3.6e-16 59.8 1.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cwf_Cwc_15 PF04889.12 KIK52935.1 - 0.53 10.0 4.2 0.75 9.5 4.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NACHT PF05729.12 KIK52936.1 - 8e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK52936.1 - 0.0024 18.3 0.0 0.0053 17.1 0.0 1.8 1 1 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.14 KIK52936.1 - 0.0024 17.2 0.1 0.0031 16.8 0.1 1.1 1 0 0 1 1 1 1 KAP family P-loop domain PIF1 PF05970.14 KIK52936.1 - 0.0026 17.0 0.0 0.0036 16.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase NB-ARC PF00931.22 KIK52936.1 - 0.0057 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KIK52936.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK52936.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIK52936.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KIK52936.1 - 0.024 15.0 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KIK52936.1 - 0.05 13.5 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK52936.1 - 0.062 13.6 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK52936.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIK52936.1 - 0.084 12.9 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFG1_ATPase PF03969.16 KIK52936.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase ABC_tran PF00005.27 KIK52936.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KIK52936.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK52936.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family YhzD PF14120.6 KIK52936.1 - 0.19 11.9 0.0 0.66 10.1 0.0 1.8 2 0 0 2 2 2 0 YhzD-like protein Hydrophobin PF01185.18 KIK52937.1 - 2.5e-23 82.5 10.2 3.3e-23 82.1 10.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK52938.1 - 1e-22 80.5 11.2 1.4e-22 80.1 11.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK52940.1 - 2.4e-23 82.6 9.9 2.9e-23 82.3 9.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF2976 PF11190.8 KIK52940.1 - 0.0071 16.1 0.6 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2976) Phage_holin_2_3 PF16080.5 KIK52940.1 - 0.18 11.6 0.4 0.18 11.6 0.4 1.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Hydrophobin PF01185.18 KIK52941.1 - 5.7e-25 87.7 9.5 6.9e-25 87.5 9.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK52944.1 - 3.1e-08 34.1 4.7 5e-08 33.5 4.6 1.4 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK52945.1 - 1.7e-07 31.8 3.0 2.2e-07 31.4 3.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Yeast-kill-tox PF09207.11 KIK52945.1 - 0.28 11.9 4.6 2.9 8.6 0.6 2.2 2 0 0 2 2 2 0 Yeast killer toxin Baculo_PEP_C PF04513.12 KIK52946.1 - 0.00073 19.6 9.3 0.0013 18.8 9.2 1.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KIK52946.1 - 0.013 15.9 1.6 0.054 14.0 1.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4134 PF13572.6 KIK52946.1 - 0.039 14.2 0.5 0.039 14.2 0.5 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4134) YbgS PF13985.6 KIK52946.1 - 0.11 12.8 0.3 0.15 12.4 0.3 1.3 1 0 0 1 1 1 0 YbgS-like protein RPW8 PF05659.11 KIK52946.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.8 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Staph_haemo PF05480.11 KIK52946.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.7 2 0 0 2 2 2 0 Staphylococcus haemolytic protein Baculo_PEP_C PF04513.12 KIK52947.1 - 7.5e-05 22.8 7.0 0.00011 22.2 7.0 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KIK52947.1 - 0.0074 16.7 1.6 0.02 15.3 1.6 1.8 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein YbgS PF13985.6 KIK52947.1 - 0.13 12.5 0.4 0.2 11.9 0.3 1.4 1 1 0 1 1 1 0 YbgS-like protein Baculo_PEP_C PF04513.12 KIK52948.1 - 0.00073 19.6 9.0 0.001 19.1 9.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 KIK52948.1 - 0.059 13.1 0.3 0.69 9.6 0.0 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RPAP3_C PF13877.6 KIK52948.1 - 0.13 12.8 0.1 0.72 10.4 0.0 2.0 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 NPV_P10 PF05531.12 KIK52948.1 - 0.16 12.5 5.8 1.3 9.5 5.0 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF148 PF02520.17 KIK52948.1 - 0.2 11.8 4.0 2 8.5 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 YlbD_coat PF14071.6 KIK52948.1 - 0.25 11.6 0.7 1.3 9.3 0.1 2.0 1 1 1 2 2 2 0 Putative coat protein FAD_binding_4 PF01565.23 KIK52949.1 - 1.4e-10 41.0 0.1 3.1e-10 40.0 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DUF883 PF05957.13 KIK52950.1 - 0.019 15.5 2.3 0.63 10.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KIK52950.1 - 0.073 12.9 0.8 0.14 12.0 0.8 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 KIK52950.1 - 0.49 9.7 9.2 0.012 15.0 2.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Helicase_C PF00271.31 KIK52951.1 - 9.7e-14 51.7 0.0 7.5e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK52951.1 - 2.1e-13 50.5 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KIK52951.1 - 1e-11 45.4 0.4 2.2e-11 44.3 0.4 1.6 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KIK52951.1 - 0.043 13.6 0.1 5.1 6.9 0.0 2.8 3 0 0 3 3 3 0 RQC domain ResIII PF04851.15 KIK52951.1 - 0.12 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WRNPLPNID PF15017.6 KIK52951.1 - 0.55 11.1 3.8 1.9 9.4 3.8 2.0 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Cwf_Cwc_15 PF04889.12 KIK52951.1 - 0.71 9.6 8.2 2.4 7.8 0.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Disaggr_assoc PF08480.10 KIK52954.1 - 0.00038 20.4 0.1 0.00049 20.0 0.1 1.3 1 0 0 1 1 1 1 Disaggregatase related DUF4325 PF14213.6 KIK52956.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) APH PF01636.23 KIK52959.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.23 KIK52960.1 - 1.1e-05 25.5 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK52960.1 - 0.001 18.5 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 KIK52960.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 KIK52960.1 - 0.033 13.6 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KIK52960.1 - 0.051 12.4 0.1 0.078 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Haspin_kinase PF12330.8 KIK52960.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_M8 PF01457.16 KIK52961.1 - 0.034 12.9 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin WD40 PF00400.32 KIK52962.1 - 3.1e-09 37.3 4.5 0.016 16.1 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.11 KIK52962.1 - 7e-05 22.6 0.0 7e-05 22.6 0.0 3.5 3 1 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KIK52962.1 - 0.049 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Lipase_3 PF01764.25 KIK52963.1 - 4.6e-05 23.3 0.0 0.00064 19.6 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) GspH PF12019.8 KIK52963.1 - 0.035 14.5 0.4 0.086 13.3 0.4 1.7 1 0 0 1 1 1 0 Type II transport protein GspH Terpene_synth_C PF03936.16 KIK52964.1 - 8.3e-06 25.3 0.1 1.8e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1569 PF07606.11 KIK52964.1 - 0.025 14.6 0.1 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) Sugar_tr PF00083.24 KIK52966.1 - 1.3e-12 47.4 2.3 1.3e-12 47.4 2.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK52966.1 - 1.2e-11 44.1 22.3 1.7e-11 43.6 22.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2583 PF10762.9 KIK52966.1 - 0.052 14.0 0.1 0.18 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) NmrA PF05368.13 KIK52967.1 - 2.9e-27 95.8 0.0 8.4e-27 94.2 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK52967.1 - 9.4e-11 41.9 0.0 3.8e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK52967.1 - 0.016 14.4 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 KIK52967.1 - 0.021 14.3 0.0 0.13 11.7 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TMEM252 PF15664.5 KIK52968.1 - 0.23 11.2 1.7 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 252 family TMEM51 PF15345.6 KIK52971.1 - 0.044 13.6 0.1 0.044 13.6 0.1 1.8 2 1 0 2 2 2 0 Transmembrane protein 51 F-box-like PF12937.7 KIK52976.1 - 1.2e-06 28.2 0.7 8.7e-06 25.5 0.7 2.3 1 1 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.7 KIK52981.1 - 8.2e-11 42.9 0.0 2.4e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK52981.1 - 0.22 11.2 0.7 7.1 6.2 0.6 2.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold APH PF01636.23 KIK52983.1 - 0.0007 19.6 0.0 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L33 PF00471.20 KIK52984.1 - 6.7e-08 32.9 0.0 8.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 RVT_1 PF00078.27 KIK52984.1 - 0.062 12.8 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Nudix_N PF12535.8 KIK52984.1 - 0.18 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Peptidase_A4 PF01828.17 KIK52985.1 - 1.7e-42 145.3 17.6 2.7e-42 144.6 17.6 1.3 1 1 0 1 1 1 1 Peptidase A4 family DUF4937 PF16291.5 KIK52987.1 - 0.00012 22.2 0.0 0.00032 20.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4937 ABM PF03992.16 KIK52987.1 - 0.00049 20.2 0.1 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF3584 PF12128.8 KIK52988.1 - 0.13 9.7 8.7 0.027 12.0 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CALM_bind PF16025.5 KIK52988.1 - 0.81 10.2 11.4 0.15 12.5 2.8 2.7 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Phage_integrase PF00589.22 KIK52989.1 - 0.002 17.9 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family Phage_integrase PF00589.22 KIK52990.1 - 1.9e-08 34.3 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Methyltransf_2 PF00891.18 KIK52991.1 - 7.7e-23 80.9 0.0 8.8e-22 77.4 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KIK52991.1 - 0.00099 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK52991.1 - 0.0031 18.2 0.0 0.015 16.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK52991.1 - 0.008 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIK52991.1 - 0.021 15.5 0.0 0.047 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK52991.1 - 0.059 14.0 0.0 0.47 11.1 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain MTS PF05175.14 KIK52991.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain MarR_2 PF12802.7 KIK52991.1 - 0.16 11.8 0.3 0.49 10.3 0.3 1.8 1 0 0 1 1 1 0 MarR family DUF2263 PF10021.9 KIK52993.1 - 1.1e-15 58.3 0.0 1.7e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) p450 PF00067.22 KIK52994.1 - 1.3e-63 215.4 0.0 2.8e-63 214.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF5127 PF17168.4 KIK52995.1 - 4e-66 223.1 1.0 6.9e-66 222.3 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIK52995.1 - 1e-44 152.9 3.8 1e-44 152.9 3.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIK52995.1 - 2e-43 148.0 0.2 8.7e-43 146.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF4964 PF16334.5 KIK52995.1 - 3.2e-06 26.6 0.0 8.5e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK52995.1 - 0.00013 21.3 0.0 0.00069 19.0 0.0 1.9 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 4HBT PF03061.22 KIK52996.1 - 2e-05 24.9 0.0 3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4366 PF14283.6 KIK52997.1 - 0.023 14.8 3.2 0.023 14.8 3.2 4.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) ETRAMP PF09716.10 KIK52997.1 - 0.029 14.4 0.4 0.029 14.4 0.4 3.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TMEM223 PF14640.6 KIK52997.1 - 0.23 11.6 0.1 0.72 10.0 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 223 MFS_1 PF07690.16 KIK52998.1 - 1.1e-45 156.2 24.6 1.1e-45 156.2 24.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK52998.1 - 7.5e-13 48.1 15.8 1.4e-11 43.9 16.1 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK52998.1 - 2.4e-05 23.8 1.2 2.4e-05 23.8 1.2 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KIK52998.1 - 0.013 13.8 1.1 0.19 10.0 0.1 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KIK52998.1 - 0.098 11.0 5.0 0.18 10.2 5.0 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Cytochrom_B561 PF03188.16 KIK52998.1 - 1.4 9.1 8.6 0.28 11.3 2.1 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Saf_2TM PF18303.1 KIK52998.1 - 5.7 6.5 6.8 8.6 5.9 0.0 2.8 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Ribosomal_L13 PF00572.18 KIK52999.1 - 2.8e-51 173.0 0.1 3.6e-51 172.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sipho_Gp37 PF14594.6 KIK52999.1 - 0.057 12.4 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein Adeno_terminal PF02459.15 KIK53000.1 - 0.0059 15.1 0.0 0.01 14.2 0.0 1.3 1 0 0 1 1 1 1 Adenoviral DNA terminal protein PYST-C1 PF09690.10 KIK53000.1 - 0.18 11.6 2.5 0.51 10.1 2.5 1.7 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) ANAPC15 PF15243.6 KIK53000.1 - 0.68 10.4 12.5 5.9 7.4 6.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RRN3 PF05327.11 KIK53000.1 - 3.6 6.0 4.3 5.4 5.4 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 KIK53000.1 - 5.3 6.3 14.6 1.7 7.9 10.1 1.9 2 0 0 2 2 2 0 NOA36 protein adh_short_C2 PF13561.6 KIK53003.1 - 4.8e-45 153.9 0.1 8.3e-45 153.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK53003.1 - 3.4e-43 147.4 0.1 5e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK53003.1 - 2.1e-09 37.5 0.0 4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK53003.1 - 0.01 15.3 0.1 0.025 14.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Asp PF00026.23 KIK53004.1 - 6.9e-20 71.7 3.0 4.4e-19 69.1 3.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Gp5_OB PF06714.11 KIK53004.1 - 0.043 14.1 0.2 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Gp5 N-terminal OB domain PIG-Y PF15159.6 KIK53005.1 - 1.7 9.6 7.4 0.12 13.3 1.3 2.4 2 2 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Aldo_ket_red PF00248.21 KIK53006.1 - 9.8e-70 235.0 0.2 1.1e-69 234.9 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1160 PF06648.11 KIK53006.1 - 0.056 13.4 0.1 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) adh_short PF00106.25 KIK53007.1 - 1.8e-38 131.9 0.0 2.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK53007.1 - 1e-32 113.6 0.0 1.3e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK53007.1 - 1.3e-10 41.5 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK53007.1 - 6.4e-05 22.5 0.1 0.00028 20.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK53007.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK53007.1 - 0.0045 16.1 0.2 0.011 14.9 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 KIK53007.1 - 0.056 13.0 0.3 0.89 9.1 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family zf-MYND PF01753.18 KIK53008.1 - 2.8e-13 49.7 15.3 4e-13 49.2 15.3 1.2 1 0 0 1 1 1 1 MYND finger RecR PF02132.15 KIK53008.1 - 0.14 11.8 1.4 0.42 10.2 1.4 1.8 1 0 0 1 1 1 0 RecR protein zf-Mss51 PF13824.6 KIK53008.1 - 0.64 10.2 8.5 1.1 9.4 8.5 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KIK53008.1 - 1.6 9.1 9.4 3.1 8.2 9.4 1.5 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding COX7C PF02935.16 KIK53010.1 - 0.1 12.8 1.2 0.37 11.1 1.2 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc zf-MYND PF01753.18 KIK53018.1 - 4.5e-07 29.8 8.8 1e-06 28.7 8.8 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KIK53018.1 - 1.5 8.7 6.6 1.1 9.2 4.1 2.1 2 0 0 2 2 2 0 HIT zinc finger Phage_holin_3_7 PF05449.11 KIK53019.1 - 0.036 14.1 6.3 0.04 13.9 1.1 2.6 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 DUF3341 PF11821.8 KIK53027.1 - 0.044 13.4 0.3 0.078 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) COX7C PF02935.16 KIK53027.1 - 0.12 12.7 0.2 0.32 11.3 0.2 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DUF4131 PF13567.6 KIK53027.1 - 0.6 9.7 2.6 1.1 8.9 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) COX7C PF02935.16 KIK53032.1 - 0.043 14.1 1.1 0.14 12.5 1.1 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DUF1218 PF06749.12 KIK53032.1 - 0.22 12.0 3.5 1.6 9.3 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) COX7C PF02935.16 KIK53034.1 - 0.87 9.9 3.7 0.37 11.1 0.7 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.16 KIK53036.1 - 2.4e-39 135.3 35.6 2.4e-39 135.3 35.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK53036.1 - 1.2e-07 31.4 8.7 1.2e-07 31.4 8.7 2.6 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KIK53038.1 - 5.4e-35 121.0 41.5 8.6e-35 120.3 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK53038.1 - 1.5e-08 34.4 5.1 1.5e-08 34.4 5.1 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF3094 PF11293.8 KIK53038.1 - 0.018 14.8 0.2 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) CaMBD PF02888.16 KIK53039.1 - 0.061 13.5 0.6 0.46 10.7 0.7 2.1 1 1 0 1 1 1 0 Calmodulin binding domain Polysacc_deac_1 PF01522.21 KIK53041.1 - 4.1e-14 52.5 0.0 8.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase p450 PF00067.22 KIK53043.1 - 2.6e-50 171.5 0.0 7.5e-50 170.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK53044.1 - 3.7e-50 171.0 0.0 1.5e-49 169.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.15 KIK53045.1 - 7.1e-232 770.7 0.1 9.3e-232 770.3 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIK53045.1 - 1.4e-97 327.6 0.0 1.4e-96 324.3 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KIK53045.1 - 8e-19 67.6 1.2 1.6e-13 50.6 0.1 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KIK53045.1 - 7.7e-15 54.6 0.0 2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KIK53045.1 - 9.8e-15 55.1 0.0 4e-13 49.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIK53045.1 - 7.3e-13 48.9 2.4 7.3e-13 48.9 2.4 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIK53045.1 - 9.4e-08 32.0 0.0 0.00078 19.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK53045.1 - 0.0051 16.3 0.0 0.055 13.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Jiv90 PF14901.6 KIK53045.1 - 0.029 14.5 0.6 0.2 11.8 0.1 2.2 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone AAA_22 PF13401.6 KIK53045.1 - 0.038 14.3 0.1 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KIK53045.1 - 0.097 12.1 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-H2C2_2 PF13465.6 KIK53048.1 - 0.00017 21.9 1.7 0.00064 20.0 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK53048.1 - 0.19 12.2 0.4 0.19 12.2 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK53048.1 - 5.4 8.1 10.0 1.1 10.3 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger GMC_oxred_C PF05199.13 KIK53049.1 - 0.0042 17.6 0.0 0.0042 17.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase ATG13 PF10033.9 KIK53050.1 - 4.8e-20 72.3 0.0 6.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 PTP_N PF12453.8 KIK53050.1 - 0.046 13.4 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Helicase_C PF00271.31 KIK53051.1 - 6.5e-09 36.1 0.0 4e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OrsD PF12013.8 KIK53051.1 - 2.1e-05 24.9 1.4 2.1e-05 24.9 1.4 2.6 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D Aminopep PF10023.9 KIK53051.1 - 0.17 11.2 0.7 2 7.7 0.1 2.6 3 0 0 3 3 3 0 Putative aminopeptidase aGPT-Pplase1 PF18723.1 KIK53052.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Nucleoporin_FG2 PF15967.5 KIK53053.1 - 0.042 12.4 1.4 0.054 12.0 1.4 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region WD40 PF00400.32 KIK53054.1 - 0.00041 21.1 6.1 0.69 10.9 0.0 5.2 4 1 2 6 6 6 2 WD domain, G-beta repeat DUF3841 PF12952.7 KIK53055.1 - 0.23 11.2 1.2 0.65 9.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3841) AAA-ATPase_like PF09820.9 KIK53058.1 - 5.3e-15 55.6 0.0 7.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Predicted AAA-ATPase Ac76 PF05814.11 KIK53060.1 - 0.0077 16.2 2.0 4 7.5 0.1 2.6 2 0 0 2 2 2 2 Orf76 (Ac76) LMBR1 PF04791.16 KIK53060.1 - 0.049 12.5 17.5 0.13 11.1 12.3 2.1 1 1 0 2 2 2 0 LMBR1-like membrane protein DASH_Dam1 PF08653.10 KIK53060.1 - 0.2 11.5 0.4 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 zf-C4pol PF14260.6 KIK53060.1 - 2.2 8.8 3.8 1.7 9.2 0.3 2.5 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta LAMTOR PF15454.6 KIK53060.1 - 2.2 8.9 11.0 2.3 8.9 0.6 3.1 3 0 0 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator TORC_N PF12884.7 KIK53060.1 - 6.2 7.7 9.7 32 5.4 0.3 3.8 2 2 1 3 3 3 0 Transducer of regulated CREB activity, N terminus DUF3450 PF11932.8 KIK53060.1 - 7.4 5.8 24.2 0.14 11.4 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Gp-FAR-1 PF05823.12 KIK53063.1 - 4.6e-05 23.8 2.0 4.6e-05 23.8 2.0 1.9 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) OmpH PF03938.14 KIK53063.1 - 0.00064 20.1 4.7 0.00064 20.1 4.7 2.3 1 1 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 KIK53063.1 - 0.001 18.5 5.8 0.001 18.5 5.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Lebercilin PF15619.6 KIK53063.1 - 0.0022 17.7 14.5 0.012 15.3 10.4 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease MeMO_Hyd_G PF02964.16 KIK53063.1 - 0.0029 17.6 0.7 0.0059 16.6 0.5 1.6 1 1 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain DUF4407 PF14362.6 KIK53063.1 - 0.0065 15.9 9.1 0.015 14.7 9.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 KIK53063.1 - 0.011 15.9 15.5 0.23 11.6 5.8 2.4 1 1 1 2 2 2 0 Tropomyosin like TPR_MLP1_2 PF07926.12 KIK53063.1 - 0.011 15.8 16.5 0.12 12.4 7.2 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KIK53063.1 - 0.012 15.8 5.5 0.012 15.8 5.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF5600 PF18150.1 KIK53063.1 - 0.033 14.8 1.3 0.91 10.1 0.0 2.8 1 1 2 3 3 2 0 Domain of unknown function (DUF5600) SHE3 PF17078.5 KIK53063.1 - 0.035 13.8 12.8 0.068 12.9 12.7 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 KIK53063.1 - 0.035 14.3 2.9 0.035 14.3 2.9 3.2 3 1 1 4 4 3 0 Homeobox associated leucine zipper Phage_Mu_Gam PF07352.12 KIK53063.1 - 0.038 13.9 2.1 0.038 13.9 2.1 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein PKcGMP_CC PF16808.5 KIK53063.1 - 0.043 13.7 2.8 0.043 13.7 2.8 3.7 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ACCA PF03255.14 KIK53063.1 - 0.045 13.6 10.3 0.37 10.6 3.9 2.4 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Psu PF07455.11 KIK53063.1 - 0.046 13.3 0.4 0.15 11.7 0.1 1.9 1 1 1 2 2 2 0 Phage polarity suppression protein (Psu) Tup_N PF08581.10 KIK53063.1 - 0.071 13.4 13.4 1.5 9.1 6.3 3.2 2 1 1 3 3 3 0 Tup N-terminal Filament PF00038.21 KIK53063.1 - 0.071 12.7 14.2 0.16 11.5 10.2 2.2 1 1 0 1 1 1 0 Intermediate filament protein Cep57_CLD PF14073.6 KIK53063.1 - 0.08 13.0 14.0 0.92 9.5 8.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Bacillus_HBL PF05791.11 KIK53063.1 - 0.082 12.7 8.1 0.03 14.1 3.8 2.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 KIK53063.1 - 0.096 12.7 18.2 0.04 13.9 11.7 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 KIK53063.1 - 0.11 11.9 13.7 0.3 10.5 6.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Prefoldin_2 PF01920.20 KIK53063.1 - 0.12 12.3 15.0 8.9 6.3 10.3 3.4 2 1 0 2 2 2 0 Prefoldin subunit FliD_C PF07195.12 KIK53063.1 - 0.13 11.7 7.5 0.14 11.5 1.9 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus YabA PF06156.13 KIK53063.1 - 0.15 12.7 14.4 0.76 10.4 4.0 3.2 1 1 2 3 3 3 0 Initiation control protein YabA PRKG1_interact PF15898.5 KIK53063.1 - 0.17 12.8 14.4 1.3 10.0 4.5 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Nore1-SARAH PF16517.5 KIK53063.1 - 0.17 11.8 2.6 0.7 9.8 0.5 2.8 2 1 1 3 3 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain TMF_DNA_bd PF12329.8 KIK53063.1 - 0.19 11.8 19.9 0.043 13.8 11.2 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding LMBR1 PF04791.16 KIK53063.1 - 0.28 10.0 3.9 0.34 9.8 3.7 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 KIK53063.1 - 0.31 11.1 10.3 4.9 7.2 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KIK53063.1 - 0.32 11.0 11.9 1.3 9.1 1.4 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOAR PF16533.5 KIK53063.1 - 0.4 10.7 8.5 0.69 9.9 5.7 2.8 1 1 1 2 2 2 0 STIM1 Orai1-activating region Pox_A_type_inc PF04508.12 KIK53063.1 - 0.56 10.2 11.4 5.6 7.0 0.1 5.0 4 1 1 5 5 4 0 Viral A-type inclusion protein repeat DUF2730 PF10805.8 KIK53063.1 - 0.58 10.3 6.7 0.25 11.5 3.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) HalX PF08663.10 KIK53063.1 - 0.67 10.3 16.8 0.16 12.3 1.4 3.3 3 0 0 3 3 3 0 HalX domain Cnn_1N PF07989.11 KIK53063.1 - 0.68 10.1 13.2 0.22 11.7 3.9 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Allexi_40kDa PF05549.11 KIK53063.1 - 0.71 9.3 10.6 0.56 9.7 3.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Sec2p PF06428.11 KIK53063.1 - 0.72 9.9 17.4 0.096 12.7 2.1 3.7 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p tRNA-synt_1e PF01406.19 KIK53063.1 - 0.72 9.1 5.7 3.7 6.8 1.9 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain bZIP_1 PF00170.21 KIK53063.1 - 0.76 9.9 14.0 0.54 10.4 6.0 3.5 2 1 2 4 4 4 0 bZIP transcription factor DUF4337 PF14235.6 KIK53063.1 - 0.78 9.8 7.5 2.9 8.0 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Sugarporin_N PF11471.8 KIK53063.1 - 0.82 9.7 4.5 1.5 8.9 2.6 2.4 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Wtap PF17098.5 KIK53063.1 - 0.94 9.4 12.2 0.12 12.3 0.7 3.4 1 1 2 3 3 3 0 WTAP/Mum2p family ZapB PF06005.12 KIK53063.1 - 0.95 10.0 16.9 1.5 9.3 6.9 3.8 2 1 2 4 4 4 0 Cell division protein ZapB DUF4140 PF13600.6 KIK53063.1 - 1 9.9 12.5 5 7.6 8.1 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 KIK53063.1 - 1.1 7.1 4.3 1.3 6.8 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tweety PF04906.13 KIK53063.1 - 1.2 7.8 6.6 0.65 8.6 1.9 2.0 1 1 1 2 2 2 0 Tweety Spc7 PF08317.11 KIK53063.1 - 1.3 7.9 15.9 8.4 5.2 15.8 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 KIK53063.1 - 1.3 8.4 18.9 0.37 10.2 11.9 2.2 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HIP1_clath_bdg PF16515.5 KIK53063.1 - 1.4 9.6 13.5 3 8.5 7.0 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 KIK53063.1 - 1.6 8.8 17.8 71 3.4 17.9 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CdvA PF18822.1 KIK53063.1 - 1.7 8.5 14.0 4.3 7.2 5.8 3.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain TSNAXIP1_N PF15739.5 KIK53063.1 - 1.8 9.0 16.4 0.47 10.8 4.9 3.0 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus CC2-LZ PF16516.5 KIK53063.1 - 1.9 8.9 14.8 3.6 8.0 2.5 3.3 1 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Uso1_p115_C PF04871.13 KIK53063.1 - 2 8.8 14.4 0.78 10.1 8.4 2.5 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 KIK53063.1 - 2 7.9 9.7 3.2 7.2 9.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 KIK53063.1 - 2 8.9 11.3 0.93 10.0 4.4 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 Spc24 PF08286.11 KIK53063.1 - 2.1 8.6 15.6 0.16 12.3 2.9 3.2 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KIK53063.1 - 2.2 8.5 12.9 1.5 9.0 7.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TEX13 PF15186.6 KIK53063.1 - 2.3 7.9 10.1 9.9 5.8 5.1 2.3 2 1 0 2 2 2 0 Testis-expressed sequence 13 protein family Golgin_A5 PF09787.9 KIK53063.1 - 2.4 7.5 15.6 4.8 6.5 12.0 2.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 CSN5_C PF18323.1 KIK53063.1 - 2.5 9.0 7.1 1.4 9.9 0.6 2.8 3 1 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain PspA_IM30 PF04012.12 KIK53063.1 - 3.4 7.2 15.7 28 4.2 13.3 2.7 1 1 1 2 2 2 0 PspA/IM30 family DUF1043 PF06295.12 KIK53063.1 - 3.5 7.7 13.3 3.4 7.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF724 PF05266.14 KIK53063.1 - 3.6 7.4 10.7 1.6 8.5 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 KIK53063.1 - 4.6 7.1 16.3 36 4.2 7.5 3.9 2 1 1 3 3 3 0 Septum formation initiator DUF5339 PF17274.2 KIK53063.1 - 4.8 8.1 10.7 7.9 7.4 5.9 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5339) M PF02370.16 KIK53063.1 - 6 7.8 20.7 11 7.0 1.5 5.0 3 1 1 4 4 4 0 M protein repeat Lectin_N PF03954.14 KIK53063.1 - 6.3 6.6 10.3 5.5e+02 0.3 10.3 2.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Occludin_ELL PF07303.13 KIK53063.1 - 6.3 7.6 9.7 13 6.6 0.6 2.8 1 1 2 3 3 3 0 Occludin homology domain DUF5320 PF17253.2 KIK53063.1 - 6.9 7.8 6.8 4.2 8.5 3.5 2.4 2 1 0 2 2 1 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 KIK53063.1 - 7.7 7.0 11.6 10 6.6 2.2 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KIK53063.1 - 8.5 6.9 22.6 17 5.9 15.3 3.0 1 1 1 3 3 3 0 Apg6 coiled-coil region JIP_LZII PF16471.5 KIK53063.1 - 8.8 6.6 12.0 1 9.6 4.0 3.2 2 2 1 3 3 2 0 JNK-interacting protein leucine zipper II KfrA_N PF11740.8 KIK53063.1 - 9 7.0 12.4 4.5 8.0 3.8 2.9 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term IFP_35_N PF07334.13 KIK53063.1 - 9.6 6.4 12.0 0.29 11.2 2.9 2.8 2 1 1 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus LRR_4 PF12799.7 KIK53064.1 - 0.39 11.2 0.1 0.39 11.2 0.1 4.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) HMMR_N PF15905.5 KIK53065.1 - 1.7 8.0 84.6 0.049 13.1 40.3 3.8 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 KIK53066.1 - 0.0065 16.5 17.4 0.0065 16.5 17.4 3.4 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 KIK53066.1 - 0.0071 16.2 19.0 0.023 14.5 9.8 2.3 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.21 KIK53066.1 - 0.11 12.0 22.3 0.07 12.7 1.7 2.5 2 0 0 2 2 2 0 Intermediate filament protein SlyX PF04102.12 KIK53066.1 - 0.23 12.1 0.1 0.23 12.1 0.1 4.2 3 1 1 4 4 4 0 SlyX YabA PF06156.13 KIK53066.1 - 0.32 11.7 21.4 0.37 11.5 1.9 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Snapin_Pallidin PF14712.6 KIK53066.1 - 0.44 11.0 20.5 0.19 12.1 0.3 3.6 2 1 0 3 3 3 0 Snapin/Pallidin TSC22 PF01166.18 KIK53066.1 - 0.61 10.4 15.5 0.36 11.2 1.9 3.8 2 1 2 4 4 4 0 TSC-22/dip/bun family PilJ PF13675.6 KIK53066.1 - 0.84 9.7 6.7 7.1 6.7 0.1 2.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.12 KIK53066.1 - 0.94 9.5 16.7 0.13 12.3 1.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KIK53066.1 - 1 9.9 26.9 6.2 7.4 5.2 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KIK53066.1 - 1.3 9.0 30.9 2.7 8.0 8.0 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACCA PF03255.14 KIK53066.1 - 1.5 8.7 12.3 1.5 8.7 0.4 2.8 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Golgin_A5 PF09787.9 KIK53066.1 - 1.8 8.0 26.8 2.5 7.5 2.8 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KIK53066.1 - 2.2 8.5 22.8 4.3 7.5 3.6 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CCDC144C PF14915.6 KIK53066.1 - 2.7 7.1 32.9 0.34 10.0 6.8 3.0 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region GAS PF13851.6 KIK53066.1 - 3 7.2 34.6 2 7.7 4.8 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TEX13 PF15186.6 KIK53066.1 - 3.2 7.4 15.5 0.38 10.4 9.1 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF4140 PF13600.6 KIK53066.1 - 5.1 7.6 10.0 5.5 7.5 0.1 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DegS PF05384.11 KIK53066.1 - 5.9 6.4 20.1 1.5 8.3 8.2 3.3 1 1 3 4 4 4 0 Sensor protein DegS Sas6_CC PF18594.1 KIK53066.1 - 7.4 6.5 10.1 0.94 9.3 0.4 3.3 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain Cep57_CLD_2 PF14197.6 KIK53066.1 - 8.3 6.6 22.3 1.6 8.9 1.1 4.4 4 1 1 5 5 5 0 Centrosome localisation domain of PPC89 JmjC PF02373.22 KIK53067.1 - 1.8e-07 31.6 0.1 5.4e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIK53067.1 - 0.098 12.3 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Gti1_Pac2 PF09729.9 KIK53069.1 - 0.041 14.0 0.3 0.054 13.6 0.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family EMC3_TMCO1 PF01956.16 KIK53071.1 - 0.0035 17.1 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PBP1_TM PF14812.6 KIK53074.1 - 0.0037 17.6 0.1 0.0062 16.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KIK53074.1 - 0.084 13.3 6.8 0.11 12.8 6.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KIK53074.1 - 0.13 11.9 2.5 0.22 11.2 0.5 1.9 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 KIK53074.1 - 0.33 9.0 2.7 0.34 8.9 2.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KIK53074.1 - 0.39 10.0 7.0 0.49 9.7 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KIK53074.1 - 2.4 7.2 8.7 2.9 6.9 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyco_transf_56 PF07429.11 KIK53079.1 - 0.097 11.8 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 CC2-LZ PF16516.5 KIK53080.1 - 0.00074 19.8 2.5 0.00091 19.6 2.5 1.2 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DMPK_coil PF08826.10 KIK53080.1 - 0.0013 18.8 1.0 0.0018 18.3 1.0 1.3 1 0 0 1 1 1 1 DMPK coiled coil domain like Rootletin PF15035.6 KIK53080.1 - 0.0095 16.0 2.0 0.01 15.8 2.0 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion NYD-SP28 PF14772.6 KIK53080.1 - 0.024 14.7 2.6 0.025 14.6 1.4 1.7 1 1 1 2 2 2 0 Sperm tail Sec34 PF04136.15 KIK53080.1 - 0.029 14.3 2.9 0.033 14.1 2.9 1.1 1 0 0 1 1 1 0 Sec34-like family TMF_DNA_bd PF12329.8 KIK53080.1 - 0.032 14.2 5.1 0.037 14.0 5.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding UPF0449 PF15136.6 KIK53080.1 - 0.042 14.3 2.5 0.046 14.2 2.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF1664 PF07889.12 KIK53080.1 - 0.042 13.9 0.7 0.045 13.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 KIK53080.1 - 0.079 11.6 0.6 0.086 11.4 0.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 KIK53085.1 - 2.8e-11 43.3 0.3 4.7e-11 42.5 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53085.1 - 6.8e-05 22.3 0.1 9.8e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK53085.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PIP49_C PF12260.8 KIK53085.1 - 0.069 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Spt5-NGN PF03439.13 KIK53086.1 - 1.2e-07 31.6 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KIK53086.1 - 0.0036 17.2 11.2 0.05 13.6 0.4 3.4 3 0 0 3 3 3 2 KOW motif Utp13 PF08625.11 KIK53087.1 - 0.031 14.2 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain AATF-Che1 PF13339.6 KIK53092.1 - 0.012 16.3 0.3 0.012 16.3 0.3 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor CENP-Q PF13094.6 KIK53092.1 - 0.029 14.6 0.6 0.032 14.4 0.6 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HTH_Tnp_Tc5 PF03221.16 KIK53093.1 - 3.9e-05 23.6 0.0 4.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_dimeris PF09026.10 KIK53095.1 - 0.0081 16.5 0.5 0.017 15.5 0.2 1.7 2 1 0 2 2 2 1 Centromere protein B dimerisation domain AAA_16 PF13191.6 KIK53099.1 - 2.4e-06 28.0 0.0 2.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK53099.1 - 3.3e-06 27.1 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KIK53099.1 - 9e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK53099.1 - 0.0026 18.3 0.0 0.0038 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK53099.1 - 0.003 17.9 0.0 0.0077 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KIK53099.1 - 0.003 16.8 0.0 0.0036 16.5 0.0 1.2 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK53099.1 - 0.0033 17.7 0.0 0.0043 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK53099.1 - 0.0052 16.7 0.0 0.0067 16.4 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KIK53099.1 - 0.0087 16.0 0.1 0.083 12.8 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_26 PF13500.6 KIK53099.1 - 0.017 14.9 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK53099.1 - 0.024 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 KIK53099.1 - 0.028 14.8 0.4 0.059 13.8 0.4 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK53099.1 - 0.036 14.6 0.0 0.048 14.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KIK53099.1 - 0.043 13.3 0.0 0.059 12.9 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KIK53099.1 - 0.059 12.8 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 KIK53099.1 - 0.063 13.2 0.0 0.084 12.8 0.0 1.6 1 1 0 1 1 1 0 NTPase Cytidylate_kin PF02224.18 KIK53099.1 - 0.073 12.8 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Cytidylate kinase DUF2075 PF09848.9 KIK53099.1 - 0.076 12.2 0.1 0.094 11.9 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KIK53099.1 - 0.078 13.1 0.2 0.11 12.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK53099.1 - 0.12 12.4 0.2 0.27 11.3 0.1 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 KIK53099.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK53099.1 - 0.36 11.3 0.2 0.36 11.3 0.2 1.9 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 KIK53100.1 - 1.3e-37 127.2 12.0 7.1e-11 42.5 0.4 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53100.1 - 8.4e-17 61.3 0.0 0.0013 18.9 0.0 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK53100.1 - 6.6e-10 38.7 1.8 0.27 11.2 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK53100.1 - 1.1e-05 25.0 0.0 0.32 10.3 0.0 3.8 4 0 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KIK53100.1 - 1.9e-05 23.8 0.0 1.2 8.1 0.0 3.4 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK53100.1 - 5.4e-05 23.5 1.6 2.5 8.7 0.1 3.9 2 2 2 4 4 4 3 PQQ-like domain Nup160 PF11715.8 KIK53100.1 - 0.0005 18.9 0.0 1.5 7.4 0.0 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KIK53100.1 - 0.001 18.7 0.7 19 5.0 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Ret2_MD PF18528.1 KIK53100.1 - 0.0026 18.1 0.0 1.5 9.3 0.0 3.0 2 1 1 3 3 3 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KIK53100.1 - 0.03 12.7 0.0 9 4.5 0.0 2.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK53100.1 - 0.046 12.5 0.0 16 4.2 0.0 2.9 1 1 2 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Acetyltransf_1 PF00583.25 KIK53102.1 - 0.00049 20.3 0.0 0.00049 20.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TrbC PF04956.13 KIK53103.1 - 0.018 15.2 0.3 0.021 15.0 0.3 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family TMEM138 PF14935.6 KIK53104.1 - 0.068 13.8 0.6 0.24 12.1 0.4 1.9 2 0 0 2 2 2 0 Transmembrane protein 138 Transposase_21 PF02992.14 KIK53106.1 - 1.2e-08 34.5 0.0 1.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF2228 PF10228.9 KIK53110.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) MTBP_mid PF14919.6 KIK53111.1 - 0.052 12.8 0.2 4.7 6.3 0.0 2.1 1 1 1 2 2 2 0 MDM2-binding HEPN_DZIP3 PF18738.1 KIK53112.1 - 0.17 11.6 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Alpha-amylase PF00128.24 KIK53116.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Atg14 PF10186.9 KIK53117.1 - 0.00096 18.3 1.8 0.0014 17.8 1.8 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Wtap PF17098.5 KIK53117.1 - 0.025 14.5 5.5 0.055 13.4 5.5 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family Cep57_CLD_2 PF14197.6 KIK53117.1 - 0.037 14.1 2.4 0.16 12.1 2.4 2.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TssO PF17561.2 KIK53117.1 - 0.073 13.2 1.4 0.15 12.2 1.4 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Prp19 PF08606.11 KIK53117.1 - 0.092 12.8 1.9 0.2 11.7 1.9 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like Golgin_A5 PF09787.9 KIK53117.1 - 0.52 9.7 11.2 0.036 13.5 5.8 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 KIK53117.1 - 0.58 10.8 9.4 12 6.6 8.4 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HemX PF04375.14 KIK53117.1 - 1.4 8.2 13.3 0.15 11.3 8.5 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase GEMIN8 PF15348.6 KIK53117.1 - 6.9 6.9 10.9 0.22 11.8 1.8 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 BRE1 PF08647.11 KIK53118.1 - 0.0064 16.5 19.8 0.0064 16.5 19.8 9.9 6 3 3 9 9 9 3 BRE1 E3 ubiquitin ligase Rnk_N PF14760.6 KIK53118.1 - 0.025 15.0 1.3 2.1 8.9 0.1 3.9 2 1 0 2 2 2 0 Rnk N-terminus Spt5_N PF11942.8 KIK53124.1 - 3.3e-07 31.2 0.2 4.6e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal PPV_E1_N PF00524.18 KIK53124.1 - 0.056 13.9 0.6 0.065 13.7 0.6 1.1 1 0 0 1 1 1 0 E1 Protein, N terminal domain Get5_C PF18514.1 KIK53125.1 - 0.14 11.9 1.5 2.4 8.0 0.1 2.8 2 0 0 2 2 2 0 Get5 C-terminal domain DUF3912 PF13051.6 KIK53125.1 - 0.15 12.3 0.2 5 7.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3912) KOW PF00467.29 KIK53125.1 - 0.16 12.0 10.9 0.64 10.1 0.3 4.2 4 0 0 4 4 4 0 KOW motif CxC2 PF18803.1 KIK53127.1 - 1.1e-38 131.6 0.2 1.1e-38 131.6 0.2 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK53127.1 - 3e-06 27.0 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK53127.1 - 2.8e-05 24.2 0.2 2.8e-05 24.2 0.2 1.7 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK53127.1 - 0.0056 16.8 9.3 0.0056 16.8 9.3 2.4 3 0 0 3 3 3 1 B-box zinc finger CxC3 PF18804.1 KIK53127.1 - 0.013 15.4 0.3 0.013 15.4 0.3 2.4 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases Cript PF10235.9 KIK53127.1 - 2 9.0 9.1 6.3 7.4 0.6 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT CRAL_TRIO PF00650.20 KIK53129.1 - 6.8e-29 100.6 0.1 1.4e-28 99.6 0.1 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain DUF3879 PF12995.7 KIK53129.1 - 0.15 11.8 0.2 0.35 10.6 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Pkinase PF00069.25 KIK53130.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53130.1 - 0.0024 17.2 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase CRAL_TRIO PF00650.20 KIK53132.1 - 1.2e-28 99.8 0.2 3.3e-21 75.7 0.0 2.2 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KIK53132.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK53134.1 - 8.4e-36 123.1 0.0 1.6e-35 122.2 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK53134.1 - 5.4e-10 39.3 0.8 1.3e-09 38.1 0.8 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain E1_DerP2_DerF2 PF02221.15 KIK53135.1 - 1e-09 38.9 0.0 1.2e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 ML domain SHR3_chaperone PF08229.11 KIK53136.1 - 0.095 11.7 0.7 0.4 9.6 0.1 1.9 2 0 0 2 2 2 0 ER membrane protein SH3 zf-CCHC PF00098.23 KIK53142.1 - 0.004 17.2 1.6 0.0091 16.0 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Endonuc-PvuII PF09225.10 KIK53142.1 - 0.14 11.9 0.7 0.32 10.7 0.5 1.7 1 1 1 2 2 2 0 Restriction endonuclease PvuII zf-CCCH_2 PF14608.6 KIK53142.1 - 0.65 10.6 3.9 1.2 9.7 3.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger WD40 PF00400.32 KIK53144.1 - 2e-119 386.0 65.3 2.3e-11 44.0 0.3 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53144.1 - 2e-50 169.0 7.4 0.00018 21.7 0.0 12.9 1 1 12 13 13 13 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53144.1 - 1.1e-30 106.7 13.9 0.0073 15.3 0.0 12.9 1 1 12 13 13 13 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53144.1 - 2.4e-16 59.2 20.0 0.14 12.2 0.1 12.4 13 0 0 13 13 13 4 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK53144.1 - 2.6e-10 40.1 0.0 0.21 10.9 0.0 7.7 5 3 3 8 8 8 2 WD40-like domain Cytochrom_D1 PF02239.16 KIK53144.1 - 6e-09 34.9 4.9 0.29 9.6 0.1 4.8 2 2 1 4 4 4 4 Cytochrome D1 heme domain NACHT PF05729.12 KIK53144.1 - 1.8e-07 31.3 0.0 3.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK53144.1 - 4.3e-06 27.2 0.0 3e-05 24.5 0.0 2.5 2 0 0 2 2 1 1 AAA ATPase domain Nuc_N PF14448.6 KIK53144.1 - 0.00017 21.4 0.6 0.13 12.2 0.0 4.8 6 0 0 6 6 5 1 Nuclease N terminal Me-amine-dh_H PF06433.11 KIK53144.1 - 0.00037 19.5 0.0 5 5.9 0.0 4.3 3 1 1 5 5 5 1 Methylamine dehydrogenase heavy chain (MADH) APS_kinase PF01583.20 KIK53144.1 - 0.00088 19.2 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK53144.1 - 0.0015 18.9 0.1 0.0097 16.3 0.0 2.5 2 0 0 2 2 1 1 RNA helicase Torsin PF06309.11 KIK53144.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Torsin PQQ PF01011.21 KIK53144.1 - 0.02 14.8 0.2 24 5.1 0.0 5.1 6 0 0 6 6 5 0 PQQ enzyme repeat TruB_C PF09142.11 KIK53144.1 - 0.038 13.8 0.8 36 4.2 0.0 4.3 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal AAA_30 PF13604.6 KIK53144.1 - 0.059 13.1 0.2 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KIK53144.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ParA PF10609.9 KIK53144.1 - 0.085 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF5114 PF17141.4 KIK53144.1 - 0.089 13.3 0.1 45 4.7 0.0 4.2 4 1 0 5 5 5 0 Domain of unknown function (DUF5114) CbiA PF01656.23 KIK53144.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KIK53144.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK53144.1 - 0.13 12.7 0.1 0.81 10.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Proteasome_A_N PF10584.9 KIK53144.1 - 0.3 10.8 19.3 70 3.2 0.2 9.8 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature DNA_pol_delta_4 PF04081.13 KIK53147.1 - 2e-17 63.8 0.1 2.1e-17 63.7 0.1 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Glyco_transf_52 PF07922.11 KIK53148.1 - 0.0053 16.1 0.1 0.01 15.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 52 F-box PF00646.33 KIK53148.1 - 0.055 13.4 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain UvrD_C_2 PF13538.6 KIK53150.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KIK53151.1 - 0.025 13.7 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase SH3_13 PF18335.1 KIK53151.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain PIF1 PF05970.14 KIK53152.1 - 4.8e-09 35.9 0.0 5.2e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK53152.1 - 5.2e-05 23.1 0.0 5.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIK53152.1 - 0.00038 19.8 0.0 0.00041 19.7 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 KIK53152.1 - 0.00049 20.5 0.0 0.00058 20.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK53152.1 - 0.0098 16.3 0.0 0.0098 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KIK53152.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.0 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KIK53152.1 - 0.066 13.0 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein Torsin PF06309.11 KIK53152.1 - 0.07 13.2 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 KIK53152.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIK53152.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Herpes_Helicase PF02689.14 KIK53152.1 - 0.15 9.9 0.0 0.15 9.9 0.0 1.0 1 0 0 1 1 1 0 Helicase IIGP PF05049.13 KIK53152.1 - 0.19 10.8 0.0 0.21 10.6 0.0 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Rod_C PF10493.9 KIK53154.1 - 0.073 11.4 0.1 0.093 11.1 0.1 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region CENP-B_dimeris PF09026.10 KIK53154.1 - 3.1 8.2 9.3 7.3 7.0 9.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Helitron_like_N PF14214.6 KIK53155.1 - 9.6e-31 107.5 0.0 1.9e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus B_lectin PF01453.24 KIK53156.1 - 0.00027 21.4 0.0 0.025 15.1 0.0 2.7 2 1 1 3 3 3 2 D-mannose binding lectin B_lectin PF01453.24 KIK53157.1 - 0.00012 22.5 0.1 0.27 11.8 0.0 2.4 1 1 1 2 2 2 2 D-mannose binding lectin CENP-T_C PF15511.6 KIK53158.1 - 0.0017 18.5 0.2 0.0033 17.5 0.1 1.5 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK53158.1 - 0.0026 17.9 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK53158.1 - 0.0061 16.9 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KIK53158.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 WD40 PF00400.32 KIK53160.1 - 3.4e-121 391.6 72.8 2.9e-10 40.6 2.6 15.1 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53160.1 - 7.6e-63 208.8 6.0 2.8e-06 27.5 0.0 13.5 1 1 12 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53160.1 - 1.3e-31 109.8 17.0 0.0022 17.0 0.0 13.2 1 1 13 14 14 14 10 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53160.1 - 1e-15 57.2 35.5 0.59 10.1 0.1 12.8 15 0 0 15 15 12 4 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK53160.1 - 5e-15 55.6 0.0 0.02 14.2 0.0 8.4 5 3 4 10 10 10 3 WD40-like domain eIF2A PF08662.11 KIK53160.1 - 6.9e-14 52.2 2.3 0.0053 16.7 0.0 6.1 1 1 5 6 6 6 4 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 KIK53160.1 - 2.4e-09 37.4 6.7 0.0015 18.4 0.1 5.7 1 1 4 5 5 5 3 Lipoprotein LpqB beta-propeller domain Me-amine-dh_H PF06433.11 KIK53160.1 - 7.6e-09 34.9 0.0 0.39 9.5 0.0 5.6 4 2 2 6 6 6 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KIK53160.1 - 6.6e-08 31.5 5.4 0.25 9.8 0.1 6.1 2 1 8 10 10 10 3 Cytochrome D1 heme domain NACHT PF05729.12 KIK53160.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Frtz PF11768.8 KIK53160.1 - 3e-07 29.2 0.1 0.016 13.5 0.0 5.7 3 2 2 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK53160.1 - 5.7e-06 26.8 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DPPIV_N PF00930.21 KIK53160.1 - 1.1e-05 24.4 2.5 2.8 6.6 0.0 7.4 3 3 2 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VID27 PF08553.10 KIK53160.1 - 1.9e-05 23.9 0.2 1.3 8.0 0.0 4.3 4 0 0 4 4 4 1 VID27 C-terminal WD40-like domain Nup160 PF11715.8 KIK53160.1 - 4.4e-05 22.3 13.4 0.043 12.5 0.7 7.0 3 3 4 8 8 8 1 Nucleoporin Nup120/160 APS_kinase PF01583.20 KIK53160.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK53160.1 - 0.00055 20.3 0.4 0.0059 17.0 0.0 3.0 3 0 0 3 3 2 1 RNA helicase CNH PF00780.22 KIK53160.1 - 0.00077 19.2 0.1 5.7 6.5 0.0 5.4 6 0 0 6 6 6 1 CNH domain DUF3748 PF12566.8 KIK53160.1 - 0.0012 18.8 1.9 24 4.9 0.0 6.0 6 3 1 7 7 5 0 Protein of unknown function (DUF3748) DUF5114 PF17141.4 KIK53160.1 - 0.0016 18.9 2.2 1.6e+02 2.9 0.0 5.8 5 1 1 6 6 6 0 Domain of unknown function (DUF5114) Peptidase_S9_N PF02897.15 KIK53160.1 - 0.03 13.1 1.1 19 3.9 0.0 4.5 4 1 1 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1258 PF06869.12 KIK53160.1 - 0.035 13.6 0.1 22 4.4 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1258) AAA_29 PF13555.6 KIK53160.1 - 0.047 13.4 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain GCV_T_C PF08669.11 KIK53160.1 - 0.075 13.0 0.4 5.6 7.0 0.0 3.3 3 0 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain ABC_tran PF00005.27 KIK53160.1 - 0.083 13.4 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KIK53160.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK53160.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK53160.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA PF00004.29 KIK53160.1 - 0.18 12.2 0.0 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Proteasome_A_N PF10584.9 KIK53160.1 - 0.24 11.1 21.6 74 3.2 0.0 9.9 11 0 0 11 11 10 0 Proteasome subunit A N-terminal signature DUF5570 PF17731.1 KIK53160.1 - 0.29 11.2 20.5 9.8 6.3 0.6 7.0 3 3 3 6 6 6 0 Family of unknown function (DUF5570) CENP-T_C PF15511.6 KIK53161.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK53161.1 - 0.00088 19.4 0.0 0.0012 19.0 0.0 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK53161.1 - 0.0028 18.0 0.0 0.0031 17.9 0.0 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK53161.1 - 0.006 16.9 0.0 0.0085 16.4 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK53161.1 - 0.034 14.5 0.0 0.038 14.3 0.0 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK53161.1 - 0.18 11.9 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCI PF01399.27 KIK53162.1 - 0.0015 19.1 0.0 0.0033 17.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain Peroxidase_2 PF01328.17 KIK53163.1 - 1.6e-47 162.4 0.0 2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 LRR_4 PF12799.7 KIK53164.1 - 0.15 12.5 1.0 0.47 10.9 0.0 2.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK53165.1 - 0.0036 17.1 0.7 0.0079 16.1 0.7 1.6 1 1 0 1 1 1 1 F-box-like Mannosyl_trans4 PF15971.5 KIK53165.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase WD40 PF00400.32 KIK53166.1 - 2.5e-123 398.4 63.2 3.3e-12 46.7 1.6 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53166.1 - 1.7e-56 188.4 6.2 8.7e-06 26.0 0.0 13.1 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53166.1 - 2.8e-32 112.0 12.8 0.025 13.6 0.1 12.1 2 2 9 12 12 12 10 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK53166.1 - 8.1e-18 65.0 0.2 1.2e-05 25.3 0.0 5.7 1 1 7 8 8 8 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK53166.1 - 1.3e-17 63.2 33.1 0.0066 16.4 0.1 13.4 15 0 0 15 15 15 5 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK53166.1 - 1.2e-10 41.2 0.0 0.099 11.9 0.0 7.5 4 3 4 9 9 9 2 WD40-like domain Cytochrom_D1 PF02239.16 KIK53166.1 - 6.3e-09 34.8 9.4 0.004 15.7 0.4 5.6 3 2 3 6 6 6 3 Cytochrome D1 heme domain NACHT PF05729.12 KIK53166.1 - 3.3e-08 33.6 0.0 7.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Me-amine-dh_H PF06433.11 KIK53166.1 - 2.7e-07 29.8 0.1 0.82 8.5 0.0 5.2 4 2 1 6 6 6 3 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 KIK53166.1 - 9.7e-07 29.3 0.0 2.9e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 KIK53166.1 - 0.00013 20.7 12.9 0.97 8.0 0.1 6.9 2 1 2 8 8 8 2 Nucleoporin Nup120/160 APS_kinase PF01583.20 KIK53166.1 - 0.00036 20.5 0.1 0.0007 19.5 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK53166.1 - 0.0011 19.3 0.0 0.0081 16.5 0.0 2.6 1 0 0 1 1 1 1 RNA helicase PALB2_WD40 PF16756.5 KIK53166.1 - 0.0013 17.8 8.4 6.5 5.6 0.2 6.6 4 2 3 7 7 7 1 Partner and localizer of BRCA2 WD40 domain DPPIV_N PF00930.21 KIK53166.1 - 0.0029 16.4 4.6 6.2 5.5 0.0 6.6 3 3 4 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5114 PF17141.4 KIK53166.1 - 0.0097 16.4 1.5 20 5.8 0.0 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF5114) AAA_22 PF13401.6 KIK53166.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK53166.1 - 0.012 16.1 0.5 0.22 12.0 0.5 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KIK53166.1 - 0.03 13.5 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 KIK53166.1 - 0.069 12.9 0.2 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KIK53166.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KIK53166.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_S9_N PF02897.15 KIK53166.1 - 0.27 10.0 3.1 6.8 5.4 0.3 4.0 5 1 0 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF3648 PF12364.8 KIK53166.1 - 4.9 7.4 12.1 5.1 7.3 0.1 4.7 4 2 2 6 6 5 0 Protein of unknown function (DUF3648) CENP-T_C PF15511.6 KIK53167.1 - 8.6e-07 29.1 0.0 1.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIK53167.1 - 4.8e-05 23.7 0.1 8.6e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KIK53167.1 - 0.00069 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KIK53167.1 - 0.0019 18.5 0.3 0.0043 17.3 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK53167.1 - 0.0025 18.2 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK53167.1 - 0.025 14.6 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Myosin_head PF00063.21 KIK53168.1 - 0.00035 19.0 0.0 0.0031 15.8 0.0 1.9 2 0 0 2 2 2 2 Myosin head (motor domain) WD40 PF00400.32 KIK53172.1 - 4.3e-124 400.8 68.4 3.4e-12 46.7 1.6 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53172.1 - 3.3e-56 187.6 9.7 5e-05 23.5 0.0 13.6 1 1 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53172.1 - 1.7e-31 109.4 17.6 0.002 17.1 0.1 13.2 1 1 13 14 14 14 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53172.1 - 2.2e-13 49.7 32.9 0.49 10.4 0.0 13.1 15 0 0 15 15 14 4 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK53172.1 - 4.5e-13 48.5 7.7 0.0043 15.6 0.1 5.9 3 2 3 6 6 6 3 Cytochrome D1 heme domain WD40_like PF17005.5 KIK53172.1 - 1.9e-10 40.6 0.2 4.7 6.4 0.0 7.8 3 3 4 8 8 8 2 WD40-like domain NACHT PF05729.12 KIK53172.1 - 3.3e-10 40.1 0.4 8e-08 32.4 0.1 2.8 2 1 0 2 2 2 1 NACHT domain Me-amine-dh_H PF06433.11 KIK53172.1 - 4.9e-09 35.5 0.1 1.3 7.8 0.0 5.4 4 2 0 5 5 5 3 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 KIK53172.1 - 1.2e-05 25.8 0.0 4.3e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 KIK53172.1 - 5.7e-05 22.0 16.3 1 8.0 0.3 7.5 2 1 2 8 8 8 3 Nucleoporin Nup120/160 APS_kinase PF01583.20 KIK53172.1 - 0.00028 20.8 0.1 0.00057 19.8 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK53172.1 - 0.0012 19.2 0.0 0.0093 16.3 0.0 2.7 1 0 0 1 1 1 1 RNA helicase Frtz PF11768.8 KIK53172.1 - 0.0013 17.1 0.0 2.9 6.1 0.0 4.6 4 3 2 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF5114 PF17141.4 KIK53172.1 - 0.0043 17.6 0.2 10 6.8 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5114) Torsin PF06309.11 KIK53172.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 KIK53172.1 - 0.0087 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KIK53172.1 - 0.013 15.3 0.1 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VID27 PF08553.10 KIK53172.1 - 0.019 14.0 0.1 1 8.3 0.0 2.9 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain AAA PF00004.29 KIK53172.1 - 0.025 15.0 0.1 0.11 12.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KIK53172.1 - 0.033 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KIK53172.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KIK53172.1 - 0.063 13.0 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ParA PF10609.9 KIK53172.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NTPase_1 PF03266.15 KIK53172.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase Peptidase_S9_N PF02897.15 KIK53172.1 - 0.33 9.7 1.7 7.4 5.3 0.1 3.5 4 1 0 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 KIK53172.1 - 3.4 7.4 17.0 83 3.0 0.2 8.6 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature CENP-T_C PF15511.6 KIK53173.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK53173.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK53173.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK53173.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK53173.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK53173.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KIK53174.1 - 3.7e-50 169.7 3.6 4.1e-50 169.5 3.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK53174.1 - 2.7e-05 24.5 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK53174.1 - 5.8e-05 23.2 0.1 9.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KIK53174.1 - 0.00035 21.2 2.3 0.00044 20.8 2.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KIK53174.1 - 0.00072 19.8 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KIK53174.1 - 0.09 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated B_lectin PF01453.24 KIK53175.1 - 0.00032 21.2 0.0 0.0056 17.2 0.0 2.0 1 1 1 2 2 2 1 D-mannose binding lectin Itfg2 PF15907.5 KIK53175.1 - 0.092 11.8 0.0 2.8 6.9 0.0 2.0 1 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 COesterase PF00135.28 KIK53177.1 - 4e-87 293.2 1.0 7.9e-86 289.0 1.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK53177.1 - 2.3e-05 24.3 0.0 5.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK53177.1 - 0.00033 20.2 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK53177.1 - 0.047 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KIK53177.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase B_lectin PF01453.24 KIK53178.1 - 4e-05 24.1 0.0 0.0041 17.7 0.0 2.1 1 1 1 2 2 2 2 D-mannose binding lectin Ldh_1_C PF02866.18 KIK53181.1 - 5.8e-48 163.0 0.0 1.8e-47 161.4 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KIK53181.1 - 4.4e-44 150.0 0.2 5.9e-44 149.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIK53181.1 - 0.0042 16.1 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.22 KIK53182.1 - 2.5e-38 132.0 0.2 4.2e-38 131.3 0.2 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK53184.1 - 1.3e-73 248.3 0.0 1.9e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK53185.1 - 4.1e-80 269.8 0.0 5.7e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Baculo_PEP_C PF04513.12 KIK53187.1 - 1.6e-05 25.0 9.4 0.36 10.9 0.0 5.1 3 2 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KIK53187.1 - 0.0087 16.2 4.2 8.4 6.5 0.0 4.2 4 0 0 4 4 4 2 Apolipophorin-III precursor (apoLp-III) CLZ PF16526.5 KIK53187.1 - 0.03 14.7 0.2 33 4.9 0.0 3.9 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 KIK53187.1 - 0.058 13.0 0.1 0.92 9.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DUF148 PF02520.17 KIK53187.1 - 0.068 13.3 1.7 4.3 7.5 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 phiKZ_IP PF12699.7 KIK53187.1 - 0.11 11.6 1.4 5.4 6.1 0.0 3.1 3 0 0 3 3 3 0 phiKZ-like phage internal head proteins Lectin_N PF03954.14 KIK53187.1 - 0.11 12.2 1.4 0.47 10.2 0.5 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Endotoxin_N PF03945.14 KIK53187.1 - 0.15 11.8 7.4 1.3 8.7 0.3 4.0 5 0 0 5 5 5 0 delta endotoxin, N-terminal domain B_lectin PF01453.24 KIK53188.1 - 1.6e-05 25.4 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 D-mannose binding lectin Baculo_PEP_C PF04513.12 KIK53189.1 - 0.013 15.5 2.8 0.023 14.7 2.3 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dak2 PF02734.17 KIK53189.1 - 0.054 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 DAK2 domain TENA_THI-4 PF03070.16 KIK53189.1 - 0.066 13.0 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family RmuC PF02646.16 KIK53189.1 - 0.068 12.3 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 RmuC family phiKZ_IP PF12699.7 KIK53189.1 - 0.077 12.1 0.5 0.12 11.5 0.5 1.4 1 1 0 1 1 1 0 phiKZ-like phage internal head proteins Herpes_VP19C PF03327.14 KIK53189.1 - 0.096 12.1 0.0 3.5 7.0 0.0 2.1 1 1 1 2 2 2 0 Herpesvirus capsid shell protein VP19C Anti-adapt_IraP PF10796.9 KIK53189.1 - 0.1 13.1 2.0 9.9 6.8 0.9 2.6 2 1 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein p450 PF00067.22 KIK53192.1 - 1e-49 169.6 0.0 1.3e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK53194.1 - 7.8e-74 249.1 0.1 1.1e-73 248.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3905 PF13045.6 KIK53194.1 - 0.16 12.0 0.1 25 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) F-box-like PF12937.7 KIK53195.1 - 6.1e-06 26.0 0.4 6.1e-06 26.0 0.4 2.9 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KIK53195.1 - 0.0025 18.2 14.4 0.82 10.2 0.0 5.0 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 KIK53196.1 - 1.2e-41 140.4 0.0 1e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK53196.1 - 6.9e-05 22.9 0.1 0.45 10.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KIK53196.1 - 0.058 13.3 0.0 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Keratin_2_head PF16208.5 KIK53196.1 - 2 8.6 36.9 4.6 7.4 36.9 1.6 1 0 0 1 1 1 0 Keratin type II head TauD PF02668.16 KIK53197.1 - 1.4e-43 149.6 0.0 2e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family B_lectin PF01453.24 KIK53198.1 - 0.0021 18.6 0.0 0.051 14.1 0.0 2.2 1 1 0 1 1 1 1 D-mannose binding lectin B_lectin PF01453.24 KIK53199.1 - 0.0015 19.0 0.1 0.08 13.5 0.0 2.4 2 1 1 3 3 3 2 D-mannose binding lectin B_lectin PF01453.24 KIK53200.1 - 0.0032 18.0 0.0 0.0032 18.0 0.0 1.0 1 0 0 1 1 1 1 D-mannose binding lectin FHA PF00498.26 KIK53201.1 - 2.3e-16 59.9 0.0 5.1e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK53201.1 - 0.00089 19.5 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF3585 PF12130.8 KIK53201.1 - 0.04 14.1 2.6 0.074 13.2 2.6 1.3 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain DUF1664 PF07889.12 KIK53201.1 - 0.11 12.5 3.1 0.15 12.1 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DEC-1_N PF04625.13 KIK53201.1 - 0.95 8.4 13.7 0.014 14.4 4.6 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Mito_fiss_reg PF05308.11 KIK53201.1 - 6 6.9 12.6 2.4 8.2 8.8 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator Exonuc_VII_L PF02601.15 KIK53204.1 - 0.56 9.7 5.4 0.85 9.1 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ERM PF00769.19 KIK53205.1 - 0.0014 18.5 0.3 0.0022 17.8 0.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Atg14 PF10186.9 KIK53205.1 - 0.003 16.7 2.9 0.0044 16.1 2.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KIK53205.1 - 0.042 14.1 4.1 0.069 13.4 4.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KIK53205.1 - 0.13 12.1 6.7 0.2 11.5 6.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Vac14_Fig4_bd PF11916.8 KIK53205.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Cep57_CLD_2 PF14197.6 KIK53205.1 - 0.17 12.0 7.2 0.38 10.9 7.2 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF724 PF05266.14 KIK53205.1 - 0.21 11.4 1.7 0.34 10.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KIK53205.1 - 0.35 10.9 2.6 0.59 10.2 2.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 KIK53206.1 - 0.0018 16.6 0.8 0.0023 16.2 0.8 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ERM PF00769.19 KIK53206.1 - 0.0035 17.2 7.9 0.0056 16.5 7.9 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Myosin_tail_1 PF01576.19 KIK53206.1 - 0.006 14.5 9.7 0.0081 14.0 9.7 1.1 1 0 0 1 1 1 1 Myosin tail BLOC1S3 PF15753.5 KIK53206.1 - 0.12 12.5 1.3 2.9 8.0 0.1 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ADIP PF11559.8 KIK53206.1 - 0.12 12.5 14.1 0.24 11.5 6.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KIK53206.1 - 0.16 12.0 9.1 0.3 11.1 9.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIK53206.1 - 0.18 10.7 7.7 0.28 10.0 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KIK53206.1 - 0.48 10.2 3.7 0.84 9.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4710 PF15828.5 KIK53206.1 - 1.7 8.8 4.5 0.52 10.5 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4710) SlyX PF04102.12 KIK53206.1 - 2.3 8.9 11.7 1.7 9.3 3.0 3.5 1 1 2 3 3 3 0 SlyX GAS PF13851.6 KIK53209.1 - 0.016 14.6 15.0 0.023 14.0 15.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 KIK53209.1 - 0.018 14.9 17.1 0.037 13.9 17.1 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 KIK53209.1 - 0.027 14.0 10.1 0.041 13.4 10.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 YbaB_DNA_bd PF02575.16 KIK53209.1 - 0.18 12.1 4.3 0.3 11.3 4.3 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Spc24 PF08286.11 KIK53209.1 - 7.9 6.8 9.9 2.3e+02 2.1 9.9 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Pkinase_fungal PF17667.1 KIK53212.1 - 8.4e-31 107.1 0.0 6e-23 81.3 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase FTO_CTD PF12934.7 KIK53212.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 FTO C-terminal domain EzrA PF06160.12 KIK53214.1 - 0.022 13.0 4.9 0.25 9.5 4.9 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA PHM7_cyt PF14703.6 KIK53214.1 - 0.2 11.9 0.9 0.41 10.8 0.9 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter GTA_holin_3TM PF11351.8 KIK53214.1 - 0.63 10.6 3.1 0.55 10.8 0.5 2.0 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF3884 PF13024.6 KIK53216.1 - 0.07 12.7 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Ank_2 PF12796.7 KIK53217.1 - 3.7e-19 69.1 4.6 3.1e-14 53.3 0.8 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK53217.1 - 6e-17 61.8 0.4 2.7e-08 34.2 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK53217.1 - 3e-13 48.6 0.2 0.07 13.7 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KIK53217.1 - 4.1e-12 46.0 3.8 0.036 14.5 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KIK53217.1 - 1.3e-07 31.8 5.7 0.019 15.2 0.1 4.1 2 1 1 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 KIK53217.1 - 4e-06 26.8 0.1 2e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK53217.1 - 0.0012 18.1 0.2 0.0027 16.9 0.2 1.5 1 0 0 1 1 1 1 NB-ARC domain Gene66 PF02053.15 KIK53217.1 - 0.045 13.4 0.1 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Gene 66 (IR5) protein Helitron_like_N PF14214.6 KIK53218.1 - 2e-19 70.6 0.0 2.2e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus NACHT PF05729.12 KIK53220.1 - 5.1e-07 29.8 0.2 2.6e-06 27.4 0.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK53220.1 - 2.9e-06 27.8 0.1 9.4e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK53220.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK53220.1 - 0.0025 18.1 0.0 0.0098 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KIK53220.1 - 0.016 14.5 0.1 2 7.6 0.0 2.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA PF00004.29 KIK53220.1 - 0.066 13.6 0.1 0.57 10.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK53220.1 - 0.081 13.3 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Atg14 PF10186.9 KIK53222.1 - 0.088 11.9 0.5 0.098 11.7 0.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 kleA_kleC PF17383.2 KIK53222.1 - 0.13 12.6 2.7 0.2 12.0 2.6 1.3 1 1 0 1 1 1 0 Uncharacterized KorC regulated protein A DUF4201 PF13870.6 KIK53226.1 - 0.21 11.3 3.8 0.37 10.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 KIK53226.1 - 0.26 11.3 2.3 0.46 10.5 2.3 1.3 1 0 0 1 1 1 0 Laminin Domain II ERM PF00769.19 KIK53226.1 - 1.2 8.9 13.6 4 7.2 13.6 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3827 PF12877.7 KIK53227.1 - 0.23 9.8 3.5 0.29 9.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Retrotran_gag_2 PF14223.6 KIK53228.1 - 0.0076 15.9 0.8 0.0091 15.7 0.8 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SAS-6_N PF16531.5 KIK53228.1 - 0.032 14.8 0.2 0.036 14.7 0.2 1.2 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal FeoB_Cyto PF17910.1 KIK53228.1 - 0.11 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 FeoB cytosolic helical domain gag_pre-integrs PF13976.6 KIK53229.1 - 6.2e-07 29.2 1.0 8.8e-07 28.7 1.0 1.3 1 1 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.14 KIK53230.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ATG13 PF10033.9 KIK53232.1 - 1.1e-17 64.6 0.0 1.3e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 BING4CT PF08149.11 KIK53235.1 - 0.066 13.0 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 BING4CT (NUC141) domain Retrotran_gag_2 PF14223.6 KIK53236.1 - 3e-15 56.1 0.0 4.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DEC-1_N PF04625.13 KIK53236.1 - 0.36 9.8 1.8 0.4 9.6 0.1 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region MVL PF12151.8 KIK53239.1 - 0.16 11.8 0.2 0.7 9.8 0.1 2.1 2 0 0 2 2 2 0 Mannan-binding protein MFS_1 PF07690.16 KIK53240.1 - 2.6e-45 154.9 44.6 3.9e-45 154.3 44.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PepSY_TM_like_2 PF16357.5 KIK53240.1 - 0.025 14.5 1.3 0.05 13.6 1.3 1.5 1 0 0 1 1 1 0 Putative PepSY_TM-like UreF PF01730.16 KIK53240.1 - 0.083 13.5 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 UreF PIG-P PF08510.12 KIK53240.1 - 0.32 10.9 0.1 0.32 10.9 0.1 3.3 3 0 0 3 3 3 0 PIG-P p450 PF00067.22 KIK53241.1 - 8.4e-69 232.5 0.0 1e-68 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KIK53242.1 - 1e-18 67.4 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Aldedh PF00171.22 KIK53243.1 - 6.4e-157 522.8 0.8 7.2e-157 522.6 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LPD7 PF18821.1 KIK53243.1 - 0.2 11.8 0.5 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Alpha_kinase PF02816.18 KIK53244.1 - 0.0045 17.1 0.3 0.041 14.0 0.0 1.9 2 0 0 2 2 2 1 Alpha-kinase family BNR PF02012.20 KIK53245.1 - 0.011 15.6 0.1 0.86 9.9 0.0 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat p450 PF00067.22 KIK53247.1 - 4.3e-69 233.5 0.0 5.8e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK53248.1 - 5e-43 147.5 0.0 6.8e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK53249.1 - 1.4e-60 205.4 0.0 1.8e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIK53250.1 - 1.1e-71 241.7 0.0 1.4e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK53250.1 - 9.2e-37 126.8 0.0 1.7e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK53250.1 - 7.3e-07 28.6 0.1 1.1e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK53250.1 - 7.8e-06 25.2 0.2 0.00031 20.0 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIK53250.1 - 8.5e-06 25.2 0.0 0.00027 20.2 0.0 2.5 2 1 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK53250.1 - 1.6e-05 24.7 0.9 0.00019 21.2 0.6 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK53250.1 - 4.9e-05 23.5 0.0 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK53250.1 - 0.0002 20.7 0.0 0.00038 19.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK53250.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KIK53250.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIK53250.1 - 0.032 13.1 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KIK53250.1 - 0.085 13.4 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK53250.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAA_hydrolase PF01557.18 KIK53251.1 - 0.061 13.0 0.2 7.8 6.1 0.1 2.1 2 0 0 2 2 2 0 Fumarylacetoacetate (FAA) hydrolase family DUF1129 PF06570.11 KIK53254.1 - 0.2 11.1 5.7 0.054 13.0 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ninjurin PF04923.12 KIK53254.1 - 0.83 9.6 5.2 0.47 10.4 1.7 2.2 2 1 0 2 2 2 0 Ninjurin Retrotran_gag_2 PF14223.6 KIK53255.1 - 7.9e-15 54.7 0.1 2.8e-06 27.0 0.1 2.3 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK53255.1 - 0.023 14.4 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) GATase_6 PF13522.6 KIK53255.1 - 0.03 14.5 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain Retrotran_gag_3 PF14244.6 KIK53255.1 - 0.035 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Aldedh PF00171.22 KIK53256.1 - 1.1e-15 57.1 0.0 1.2e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_10 PF13374.6 KIK53257.1 - 9.8e-81 263.7 5.0 4.5e-11 42.2 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53257.1 - 6.5e-68 225.0 12.6 6.7e-14 51.9 0.2 8.5 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53257.1 - 5.7e-24 82.3 10.7 0.03 14.3 0.0 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53257.1 - 3.7e-18 64.5 17.4 0.043 13.7 0.1 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53257.1 - 7.3e-18 64.8 5.4 0.0036 17.8 0.1 7.5 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53257.1 - 4e-15 54.6 7.8 0.17 12.1 0.1 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK53257.1 - 8.3e-15 53.7 17.1 0.11 12.8 0.1 8.4 9 0 0 9 9 7 4 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK53257.1 - 1.8e-14 53.6 0.9 0.35 11.0 0.0 8.4 4 2 4 8 8 8 1 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.6 KIK53257.1 - 9.5e-11 41.3 15.7 0.35 11.3 0.0 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK53257.1 - 1.2e-08 34.7 0.0 18 6.3 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK53257.1 - 2.3e-08 34.1 8.5 0.012 15.8 0.0 7.4 5 1 3 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 KIK53257.1 - 9.6e-07 28.2 0.2 2.8e-06 26.7 0.2 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_20 PF14561.6 KIK53257.1 - 2.9e-06 27.5 4.2 9.1 6.7 0.0 6.4 3 2 4 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK53257.1 - 5.1e-06 27.0 0.1 42 4.9 0.0 6.5 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK53257.1 - 7.3e-05 23.2 6.1 4.5 8.1 0.1 7.0 6 0 0 6 6 5 1 Tetratricopeptide repeat Paf67 PF10255.9 KIK53257.1 - 0.00013 21.1 0.9 0.026 13.5 0.0 3.4 3 1 1 4 4 4 1 RNA polymerase I-associated factor PAF67 SRP_TPR_like PF17004.5 KIK53257.1 - 0.00017 21.6 0.0 5.8 7.0 0.0 5.7 3 2 0 4 4 3 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 KIK53257.1 - 0.00032 20.7 9.2 9.4 6.4 0.0 7.7 9 0 0 9 9 9 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 KIK53257.1 - 0.00044 20.0 0.9 0.99 9.1 0.0 5.0 2 1 1 5 5 5 1 26S proteasome subunit RPN7 YqaH PF17448.2 KIK53257.1 - 0.0006 20.1 0.2 4.9 7.5 0.0 5.1 2 1 1 5 5 4 1 Uncharacterized YqaH-like PPR PF01535.20 KIK53257.1 - 0.00071 19.7 3.9 2.8 8.4 0.0 6.9 9 0 0 9 9 8 1 PPR repeat Foie-gras_1 PF11817.8 KIK53257.1 - 0.013 15.1 3.4 7.5 6.0 0.0 5.6 5 2 0 6 6 6 0 Foie gras liver health family 1 PAD_M PF08527.10 KIK53257.1 - 0.017 14.8 5.3 20 4.8 0.0 4.4 1 1 3 4 4 4 0 Protein-arginine deiminase (PAD) middle domain TPR_MalT PF17874.1 KIK53257.1 - 0.029 13.8 7.0 2.1 7.6 0.0 4.2 1 1 2 3 3 3 0 MalT-like TPR region AAA_22 PF13401.6 KIK53257.1 - 0.057 13.7 0.0 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KIK53257.1 - 0.066 12.8 0.3 0.16 11.6 0.2 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KIK53257.1 - 0.089 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF4866 PF16160.5 KIK53257.1 - 0.15 11.4 3.0 16 4.7 0.0 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4866) SPOB_a PF14689.6 KIK53257.1 - 0.15 11.8 8.5 22 4.8 0.0 5.9 6 1 1 7 7 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain Titin_Ig-rpts PF06582.12 KIK53257.1 - 0.52 10.3 4.2 1.4e+02 2.5 0.1 4.8 5 0 0 5 5 5 0 Titin repeat DUF4404 PF14357.6 KIK53257.1 - 7.2 7.3 7.4 86 3.9 0.0 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4404) Glyco_hydro_43 PF04616.14 KIK53258.1 - 5.4e-32 111.3 3.9 8.1e-32 110.7 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIK53258.1 - 1.9e-23 83.3 0.1 2.7e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PARP PF00644.20 KIK53259.1 - 2.1e-10 40.5 0.0 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KIK53259.1 - 2e-09 37.3 0.1 7.1e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK53259.1 - 0.00061 20.1 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 RWD domain Sen15 PF09631.10 KIK53260.1 - 2.5e-16 59.8 0.0 2.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Sulfatase PF00884.23 KIK53261.1 - 2.8e-50 171.5 0.0 6.9e-49 166.9 0.0 2.2 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KIK53261.1 - 3.4e-07 30.5 0.4 1e-05 25.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KIK53261.1 - 4.1e-07 29.9 0.1 3.7e-05 23.5 0.2 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KIK53261.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.6 KIK53261.1 - 0.039 14.7 0.2 0.092 13.5 0.2 1.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KIK53261.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF229 PF02995.17 KIK53261.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Questin_oxidase PF14027.6 KIK53262.1 - 1.8e-81 274.4 0.0 2.1e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like DUF4589 PF15252.6 KIK53263.1 - 0.044 13.8 1.4 0.056 13.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) VWA PF00092.28 KIK53264.1 - 3.6e-08 33.8 0.0 5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIK53264.1 - 0.0033 17.4 0.0 0.0069 16.3 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK53264.1 - 0.0048 17.5 0.0 0.0092 16.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 KIK53264.1 - 0.12 11.8 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Copine COX7a PF02238.15 KIK53265.1 - 6.6e-16 58.5 0.1 8.6e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII YEATS PF03366.16 KIK53266.1 - 3.9e-37 126.1 0.2 7.9e-37 125.1 0.0 1.6 2 0 0 2 2 2 1 YEATS family M16C_assoc PF08367.11 KIK53266.1 - 0.35 10.0 3.1 0.53 9.4 3.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated PI3_PI4_kinase PF00454.27 KIK53267.1 - 2.4e-56 191.4 0.0 5.3e-56 190.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KIK53267.1 - 1.2e-29 103.6 1.2 1.2e-29 103.6 1.2 2.0 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KIK53267.1 - 8.3e-29 99.5 0.0 5.3e-27 93.7 0.1 3.1 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KIK53267.1 - 4.3e-11 42.4 0.2 9.1e-11 41.4 0.2 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 KIK53267.1 - 0.015 15.2 0.1 0.19 11.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) HEAT PF02985.22 KIK53267.1 - 0.02 15.1 0.5 0.26 11.7 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 KIK53267.1 - 0.096 13.1 0.7 44 4.6 0.0 4.9 6 0 0 6 6 6 0 HEAT repeats Acyl-CoA_dh_C PF12806.7 KIK53267.1 - 0.19 11.9 1.2 0.84 9.8 1.2 2.1 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF948 PF06103.11 KIK53267.1 - 0.42 10.9 2.2 25 5.2 0.2 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GATA PF00320.27 KIK53270.1 - 2.7e-08 33.3 4.2 4.9e-08 32.4 4.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Activator_LAG-3 PF11498.8 KIK53270.1 - 0.25 10.3 23.4 1.9 7.4 19.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 ArfGap PF01412.18 KIK53270.1 - 0.25 11.4 2.5 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf TFIIA PF03153.13 KIK53270.1 - 3.6 7.5 17.0 0.22 11.5 10.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 KIK53270.1 - 5.3 7.3 5.3 3 8.1 1.3 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 KIK53270.1 - 5.9 6.4 17.3 0.16 11.6 9.8 2.0 2 0 0 2 2 2 0 Spt20 family Mgm101p PF06420.12 KIK53274.1 - 1.6e-85 284.8 0.0 2e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PAP_central PF04928.17 KIK53275.1 - 3.5e-108 360.3 0.0 4.4e-108 360.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KIK53275.1 - 1e-55 188.0 0.0 1.6e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KIK53275.1 - 2.1e-10 40.7 0.0 5.5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KIK53275.1 - 0.0017 18.2 0.1 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 KIK53275.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Beta_helix PF13229.6 KIK53276.1 - 2.4e-08 34.0 30.2 1.3e-06 28.4 17.1 3.2 1 1 2 3 3 3 3 Right handed beta helix region RRM_1 PF00076.22 KIK53277.1 - 3.7e-17 61.9 0.0 6.7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK53277.1 - 2.5e-05 24.3 0.0 5.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KIK53277.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TrkA_C PF02080.21 KIK53277.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain Nup35_RRM_2 PF14605.6 KIK53277.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GREB1 PF15782.5 KIK53277.1 - 5.3 4.0 7.6 6.3 3.8 7.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 KIK53278.1 - 1.1e-210 701.0 0.0 1.3e-210 700.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CUE PF02845.16 KIK53279.1 - 1.2e-06 28.1 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain Rhomboid PF01694.22 KIK53279.1 - 0.00021 21.3 5.6 0.00037 20.5 5.6 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KIK53279.1 - 0.016 15.8 0.3 0.032 14.8 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) E3_UbLigase_EDD PF11547.8 KIK53279.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TRP PF06011.12 KIK53282.1 - 5.3e-31 107.8 20.4 1.9e-30 105.9 20.4 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KIK53282.1 - 0.091 13.1 0.4 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 ML-like domain CNH PF00780.22 KIK53283.1 - 0.00012 21.8 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 2 CNH domain SNF PF00209.18 KIK53284.1 - 0.024 13.4 1.1 0.023 13.4 1.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Bestrophin PF01062.21 KIK53285.1 - 8.6e-39 133.7 0.4 1e-21 77.6 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel TMEM72 PF16054.5 KIK53285.1 - 0.04 13.6 0.6 0.075 12.7 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 DUF3087 PF11286.8 KIK53285.1 - 0.13 11.7 1.3 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Glyco_hydro_18 PF00704.28 KIK53286.1 - 1.3e-60 205.8 1.4 1.7e-60 205.4 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.32 KIK53287.1 - 2.2e-64 211.9 6.1 1.7e-11 44.5 0.1 6.7 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53287.1 - 1.3e-21 76.6 0.7 0.014 15.6 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK53287.1 - 2.8e-10 40.4 0.3 6.3e-05 22.9 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK53287.1 - 8.5e-09 35.2 0.2 0.59 9.4 0.0 5.5 4 2 1 5 5 5 2 WD40-like domain nos_propeller PF18764.1 KIK53287.1 - 1.5e-07 31.2 6.2 2.4 8.1 0.0 6.2 7 0 0 7 7 7 2 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KIK53287.1 - 1.8e-05 23.6 0.3 6.1 5.4 0.0 4.9 3 1 3 6 6 6 1 Nucleoporin Nup120/160 PLL PF18587.1 KIK53287.1 - 3.8e-05 23.8 0.0 1.4 9.0 0.0 4.4 3 2 2 5 5 5 2 PTX/LNS-Like (PLL) domain Ge1_WD40 PF16529.5 KIK53287.1 - 4.5e-05 22.6 0.1 11 4.9 0.0 5.2 2 1 4 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53287.1 - 6.4e-05 22.8 0.1 14 5.8 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat potato_inhibit PF00280.18 KIK53287.1 - 0.00014 22.5 0.1 7.6 7.3 0.0 4.6 3 2 2 5 5 5 1 Potato inhibitor I family TTR-52 PF01060.23 KIK53287.1 - 0.0013 19.4 0.2 12 6.7 0.0 4.6 1 1 1 3 3 3 0 Transthyretin-like family DsbC_N PF10411.9 KIK53287.1 - 0.0028 17.1 2.5 85 2.7 0.0 5.7 6 0 0 6 6 6 0 Disulfide bond isomerase protein N-terminus NHL PF01436.21 KIK53287.1 - 0.0034 17.3 2.1 45 4.3 0.0 5.4 6 0 0 6 6 6 0 NHL repeat Peptidase_S9_N PF02897.15 KIK53287.1 - 0.012 14.4 0.1 2.5 6.8 0.0 2.8 2 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Coatomer_WDAD PF04053.14 KIK53287.1 - 0.02 13.9 1.6 7.6 5.5 0.1 3.4 1 1 2 3 3 3 0 Coatomer WD associated region Imm17 PF15562.6 KIK53287.1 - 0.043 13.7 0.0 15 5.5 0.0 3.9 5 0 0 5 5 5 0 Immunity protein 17 UNC-93 PF05978.16 KIK53287.1 - 0.059 13.1 1.7 44 3.8 0.0 4.7 4 1 2 6 6 6 0 Ion channel regulatory protein UNC-93 DUF4988 PF16378.5 KIK53287.1 - 0.087 12.5 0.1 25 4.5 0.0 3.6 1 1 2 4 4 4 0 Domain of unknown function Pectate_lyase_3 PF12708.7 KIK53287.1 - 0.44 10.4 10.6 13 5.5 0.5 4.6 1 1 4 5 5 5 0 Pectate lyase superfamily protein Asp_protease PF09668.10 KIK53288.1 - 6e-09 35.8 0.0 9.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 KIK53288.1 - 0.00024 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.31 KIK53288.1 - 0.0059 16.5 3.1 0.048 13.6 0.2 2.3 2 0 0 2 2 2 1 UBA/TS-N domain gag-asp_proteas PF13975.6 KIK53288.1 - 0.068 13.7 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK53288.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease UIM PF02809.20 KIK53288.1 - 0.16 11.9 0.7 0.34 10.9 0.7 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif HTH_8 PF02954.19 KIK53288.1 - 0.24 11.2 2.7 12 5.7 0.5 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Atg29_N PF18388.1 KIK53289.1 - 9.5e-16 57.4 0.5 2e-15 56.3 0.5 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain Lge1 PF11488.8 KIK53289.1 - 0.018 15.2 0.8 0.036 14.2 0.8 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Lin-8 PF03353.15 KIK53289.1 - 1.8 8.1 8.7 2.7 7.5 8.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIID-18kDa PF02269.16 KIK53290.1 - 6.3e-34 115.9 0.2 1.9e-33 114.3 0.2 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 KIK53290.1 - 0.0014 18.9 1.0 0.0038 17.5 1.0 1.8 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Adaptin_binding PF10199.9 KIK53290.1 - 0.032 14.8 0.3 0.062 13.9 0.3 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 FAA_hydrolase PF01557.18 KIK53291.1 - 5.3e-59 199.5 0.0 7e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CDC14 PF08045.11 KIK53292.1 - 8.9e-33 113.6 0.1 8.4e-28 97.3 0.1 3.2 2 1 0 2 2 2 2 Cell division control protein 14, SIN component RYDR_ITPR PF01365.21 KIK53292.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 RIH domain Coiled-coil_56 PF09813.9 KIK53293.1 - 9.2e-08 32.1 0.3 2.9e-07 30.5 0.1 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 56 NAD_binding_3 PF03447.16 KIK53293.1 - 0.02 15.5 0.1 0.028 15.1 0.1 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2269 PF10027.9 KIK53294.1 - 0.069 13.2 1.6 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF3754 PF12576.8 KIK53294.1 - 0.089 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Cu-oxidase PF00394.22 KIK53297.1 - 1.2e-39 136.0 1.5 1e-38 132.9 0.2 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK53297.1 - 5.7e-35 119.9 2.8 1.2e-27 96.3 0.0 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK53297.1 - 5.7e-32 110.3 2.7 1.3e-31 109.1 0.3 2.5 3 0 0 3 3 3 1 Multicopper oxidase Syja_N PF02383.18 KIK53298.1 - 3.1e-79 266.6 0.1 5.9e-79 265.7 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain Fer4_14 PF13394.6 KIK53298.1 - 0.35 11.0 1.2 9.7 6.4 0.0 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain Rft-1 PF04506.13 KIK53299.1 - 3.6e-127 425.2 10.5 4.3e-127 425.0 10.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KIK53299.1 - 0.0013 18.2 11.6 0.0013 18.2 11.6 3.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein MtN3_slv PF03083.16 KIK53299.1 - 0.036 14.1 0.7 0.12 12.4 0.7 1.9 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange UPF0029 PF01205.19 KIK53300.1 - 4.8e-31 107.2 0.0 7.1e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Fungal_trans PF04082.18 KIK53301.1 - 2.6e-05 23.4 0.1 4.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK53301.1 - 0.00018 21.6 8.0 0.00032 20.7 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_fungal PF17667.1 KIK53302.1 - 2.3e-26 92.6 0.0 2.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK53302.1 - 2.2e-05 23.9 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4746 PF15928.5 KIK53303.1 - 0.16 11.4 13.4 0.2 11.1 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PAF-AH_p_II PF03403.13 KIK53303.1 - 0.24 9.9 2.3 0.33 9.4 2.3 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Otopetrin PF03189.13 KIK53303.1 - 0.65 8.7 1.0 0.76 8.5 1.0 1.1 1 0 0 1 1 1 0 Otopetrin TFIIF_alpha PF05793.12 KIK53303.1 - 3.6 6.1 24.3 4.8 5.7 24.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NPR3 PF03666.13 KIK53303.1 - 4.7 5.9 15.4 5.3 5.7 15.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 KIK53303.1 - 5.1 5.8 6.3 5.4 5.7 6.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 KIK53303.1 - 6.6 5.4 15.2 7.7 5.2 15.2 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 KIK53303.1 - 8.8 5.8 8.8 12 5.3 8.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4470 PF14737.6 KIK53304.1 - 1.4e-19 70.0 0.0 3.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIK53304.1 - 6.4e-09 35.7 12.9 1.8e-08 34.4 12.9 1.8 1 0 0 1 1 1 1 MYND finger DUF3844 PF12955.7 KIK53304.1 - 0.27 11.4 2.5 0.7 10.1 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) PCRF PF03462.18 KIK53305.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 PCRF domain cNMP_binding PF00027.29 KIK53306.1 - 0.0028 17.7 0.1 0.0032 17.5 0.1 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain UQ_con PF00179.26 KIK53307.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Pkinase PF00069.25 KIK53309.1 - 9.3e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53309.1 - 0.13 11.5 0.1 0.7 9.1 0.1 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1418 PF07214.12 KIK53311.1 - 0.0011 18.8 2.4 0.04 13.8 0.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1418) Cyt_c_ox_IV PF12270.8 KIK53314.1 - 0.042 14.0 0.4 0.05 13.7 0.4 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF1129 PF06570.11 KIK53314.1 - 0.06 12.8 1.8 2.5 7.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF716 PF04819.12 KIK53314.1 - 0.38 10.4 4.3 5.8 6.5 4.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF716) DUF775 PF05603.12 KIK53316.1 - 1.3e-58 197.9 0.0 1.4e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) COesterase PF00135.28 KIK53318.1 - 2.6e-69 234.5 0.0 2.2e-68 231.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK53318.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KIK53319.1 - 4.8e-84 283.1 0.0 6.1e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK53319.1 - 1.9e-05 24.6 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK53320.1 - 4e-83 280.0 0.0 2.5e-82 277.4 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK53320.1 - 2e-05 24.6 0.0 3.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK53320.1 - 0.21 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.7 KIK53321.1 - 1.1e-05 25.2 0.3 5.9e-05 22.9 0.2 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK53321.1 - 0.014 15.2 1.5 0.56 10.1 0.5 3.1 3 0 0 3 3 3 0 F-box domain HAUS-augmin3 PF14932.6 KIK53321.1 - 0.14 11.7 1.0 0.22 11.1 1.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 F-box-like PF12937.7 KIK53322.1 - 8.2e-08 32.0 0.8 8.2e-08 32.0 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK53322.1 - 0.0018 18.1 7.2 0.0036 17.1 4.0 3.0 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIK53322.1 - 0.089 13.3 16.1 2.7 8.5 0.5 5.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK53323.1 - 3.5e-08 33.2 1.0 1.5e-07 31.2 0.5 2.3 2 1 0 2 2 2 1 F-box-like DUF5082 PF16888.5 KIK53323.1 - 0.014 15.7 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) F-box PF00646.33 KIK53323.1 - 0.12 12.3 0.5 0.12 12.3 0.5 2.8 3 0 0 3 3 3 0 F-box domain Acyl-CoA_dh_1 PF00441.24 KIK53324.1 - 2.4e-38 131.7 0.6 3.8e-38 131.1 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK53324.1 - 9.3e-19 67.4 0.1 1.7e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK53324.1 - 7.8e-13 48.9 0.1 1.4e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIK53324.1 - 6.9e-09 36.4 0.1 8.6e-08 32.8 0.1 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KIK53324.1 - 1.7e-05 24.6 0.5 5.6e-05 22.9 0.2 2.0 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.16 KIK53325.1 - 7.3e-24 84.3 25.2 7.3e-24 84.3 25.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3899 PF13038.6 KIK53325.1 - 0.065 13.7 2.7 4.1 8.0 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Aminotran_1_2 PF00155.21 KIK53326.1 - 3.6e-51 174.4 0.0 4.6e-42 144.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 KIK53326.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF4080 PF13311.6 KIK53326.1 - 0.17 12.1 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Tmemb_18A PF09771.9 KIK53326.1 - 0.18 12.2 0.0 0.63 10.4 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 188 Pkinase_Tyr PF07714.17 KIK53327.1 - 5.7e-43 147.1 0.0 6.7e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53327.1 - 5.1e-32 111.3 0.0 6.6e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK53327.1 - 0.026 14.4 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK53327.1 - 0.063 12.0 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Fungal_trans_2 PF11951.8 KIK53328.1 - 1e-22 80.5 0.0 1.4e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_GP20 PF06810.11 KIK53328.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Aminotran_1_2 PF00155.21 KIK53329.1 - 0.0002 20.7 0.4 0.0002 20.6 0.4 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase_Tyr PF07714.17 KIK53331.1 - 1.2e-27 96.9 0.0 1.4e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53331.1 - 9.2e-21 74.4 0.0 1e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK53331.1 - 0.0089 14.8 0.0 0.011 14.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK53331.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 KIK53332.1 - 3.5e-19 68.9 0.2 1.4e-18 66.9 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 KIK53333.1 - 2e-14 53.6 0.0 2.3e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MNSV_P7B PF06692.11 KIK53334.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.5 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein Fungal_trans_2 PF11951.8 KIK53335.1 - 1.6e-05 23.9 0.0 2.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 KIK53336.1 - 4.5e-25 88.6 0.0 5.5e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KIK53336.1 - 0.008 15.0 0.0 0.018 13.8 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 KIK53336.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIK53336.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Pkinase_Tyr PF07714.17 KIK53337.1 - 8.7e-17 61.3 0.0 9.9e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53337.1 - 6e-11 42.2 0.0 7.1e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fungal_trans_2 PF11951.8 KIK53338.1 - 7e-20 71.2 0.0 1.6e-19 70.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pkinase_Tyr PF07714.17 KIK53338.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PRIMA1 PF16101.5 KIK53338.1 - 9.6 6.3 7.2 27 4.8 7.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Aminotran_1_2 PF00155.21 KIK53339.1 - 4.5e-21 75.4 0.0 8.1e-16 58.1 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Pkinase_Tyr PF07714.17 KIK53341.1 - 0.0011 18.4 0.0 0.0012 18.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53341.1 - 0.014 14.8 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain RabGAP-TBC PF00566.18 KIK53342.1 - 8.7e-34 117.1 0.0 1.1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CHAT PF12770.7 KIK53343.1 - 5.7e-40 137.5 0.0 8.8e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK53343.1 - 0.0034 17.2 6.8 0.45 10.5 0.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PsbW PF07123.12 KIK53344.1 - 0.16 11.9 0.3 0.26 11.3 0.3 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Pkinase_Tyr PF07714.17 KIK53347.1 - 2.5e-40 138.4 0.0 4.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53347.1 - 2e-30 106.0 0.1 6.5e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain MA3 PF02847.17 KIK53347.1 - 4.6e-08 33.0 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 MA3 domain HC2 PF07382.11 KIK53347.1 - 2.7e-07 30.8 25.6 2.7e-07 30.8 25.6 1.5 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 CDC45 PF02724.14 KIK53347.1 - 0.0092 14.3 1.7 0.014 13.7 1.7 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF4778 PF16008.5 KIK53347.1 - 0.085 12.9 8.1 0.1 12.7 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) APH PF01636.23 KIK53347.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4776 PF16003.5 KIK53347.1 - 0.2 10.6 10.3 0.37 9.7 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Plasmodium_Vir PF05795.11 KIK53347.1 - 4.4 6.6 6.9 9.2 5.6 6.9 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Aminotran_1_2 PF00155.21 KIK53348.1 - 7.5e-07 28.6 0.0 8.5e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1685 PF07939.11 KIK53349.1 - 0.012 15.3 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Pkinase_Tyr PF07714.17 KIK53350.1 - 1.7e-14 53.8 0.0 2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53350.1 - 9.5e-11 41.6 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53351.1 - 8.9e-20 71.1 0.0 1e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53351.1 - 6.4e-14 51.9 0.0 8.1e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RabGAP-TBC PF00566.18 KIK53352.1 - 8.2e-33 113.9 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Epiglycanin_C PF14654.6 KIK53352.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Fungal_trans_2 PF11951.8 KIK53353.1 - 1.1e-11 44.1 0.1 1.3e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_GP20 PF06810.11 KIK53353.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Pkinase_Tyr PF07714.17 KIK53354.1 - 5.4e-40 137.3 0.0 7.1e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53354.1 - 8.1e-31 107.3 0.0 1.2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK53354.1 - 0.01 15.8 0.5 0.024 14.5 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KIK53355.1 - 2.2e-31 109.2 0.0 6e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53355.1 - 2.8e-23 82.5 0.0 4.2e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK53355.1 - 2.9e-05 23.6 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KIK53357.1 - 3.9e-38 131.2 0.0 5.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53357.1 - 5.9e-31 107.8 0.0 9.2e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1484 PF07363.11 KIK53357.1 - 0.085 13.9 1.6 0.31 12.1 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) APH PF01636.23 KIK53357.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 KIK53358.1 - 1.7e-23 83.1 0.1 2e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_GP20 PF06810.11 KIK53358.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Pkinase_Tyr PF07714.17 KIK53361.1 - 4.4e-39 134.3 0.0 5.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53361.1 - 2.8e-30 105.6 0.0 3.6e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK53361.1 - 0.013 15.4 0.1 0.031 14.2 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SOG2 PF10428.9 KIK53362.1 - 2.3e-19 70.0 1.1 2.3e-19 70.0 1.1 2.0 1 1 1 2 2 2 1 RAM signalling pathway protein Nitroreductase PF00881.24 KIK53363.1 - 2.3e-22 79.9 0.0 5e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIK53363.1 - 8.3e-08 32.1 0.0 0.0027 17.3 0.0 2.9 2 1 1 3 3 3 3 Putative TM nitroreductase Pkinase_Tyr PF07714.17 KIK53364.1 - 5.7e-08 32.4 0.0 6.8e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53364.1 - 0.00027 20.4 0.0 0.00032 20.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KIK53365.1 - 1.9e-35 122.5 0.0 1.6e-34 119.5 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53365.1 - 2.6e-28 99.0 0.0 9.9e-24 84.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK53365.1 - 3e-06 26.8 0.0 5.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Nitroreductase PF00881.24 KIK53367.1 - 1.5e-24 86.9 0.0 2.5e-24 86.2 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIK53367.1 - 3.7e-08 33.2 0.0 0.0083 15.7 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase NmrA PF05368.13 KIK53369.1 - 1.9e-20 73.4 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK53369.1 - 1.4e-07 31.6 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK53369.1 - 0.0062 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIK53369.1 - 0.0084 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KIK53369.1 - 0.13 13.1 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold INCENP_ARK-bind PF03941.15 KIK53370.1 - 0.12 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region zf-C2H2 PF00096.26 KIK53372.1 - 5e-06 26.7 7.5 0.00058 20.2 0.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK53372.1 - 0.00014 22.4 8.9 0.0068 17.2 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK53372.1 - 0.0054 17.0 1.2 0.011 16.0 1.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIK53372.1 - 0.014 16.0 0.6 0.014 16.0 0.6 3.7 4 1 1 5 5 5 0 FOXP coiled-coil domain DUF4729 PF15866.5 KIK53372.1 - 0.017 14.4 3.7 0.18 11.1 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4729) zf-Di19 PF05605.12 KIK53372.1 - 0.084 13.2 8.5 3.3 8.1 0.1 3.8 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIK53372.1 - 0.18 11.8 2.5 0.64 10.1 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK53372.1 - 0.24 11.9 8.5 3.1 8.4 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK53375.1 - 0.00057 20.5 10.3 0.31 12.0 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK53375.1 - 0.0013 19.1 9.8 0.34 11.4 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KIK53375.1 - 0.026 14.8 5.7 0.95 9.8 2.3 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KIK53375.1 - 0.028 14.7 0.5 0.036 14.4 0.5 1.3 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KIK53375.1 - 0.21 12.1 8.5 13 6.4 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 KIK53375.1 - 0.42 11.3 4.1 2.4 8.9 1.1 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain LapA_dom PF06305.11 KIK53376.1 - 0.14 12.0 0.3 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase_Tyr PF07714.17 KIK53378.1 - 2.8e-36 125.1 0.0 3.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53378.1 - 5.3e-27 94.8 0.0 6.5e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK53378.1 - 0.053 13.4 0.6 0.1 12.5 0.6 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KIK53380.1 - 7.9e-16 58.2 0.1 8e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53380.1 - 8.4e-07 28.5 0.0 9.2e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK53380.1 - 0.00031 20.2 0.0 0.00032 20.1 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK53380.1 - 0.089 11.6 0.0 0.094 11.5 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase G6PD_C PF02781.16 KIK53381.1 - 0.075 12.2 0.3 0.083 12.1 0.3 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Emaravirus_P4 PF16505.5 KIK53381.1 - 0.13 11.3 0.0 3.9 6.4 0.0 2.0 1 1 1 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily zf-C2H2 PF00096.26 KIK53386.1 - 0.00091 19.6 1.2 0.00091 19.6 1.2 3.1 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK53386.1 - 0.0019 18.9 8.0 0.017 15.9 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK53386.1 - 0.02 15.2 0.4 0.038 14.3 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KIK53386.1 - 6.2 7.4 8.7 6.2 7.4 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK53387.1 - 0.0016 19.1 6.7 1.2 10.1 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK53387.1 - 0.027 14.9 9.4 0.13 12.8 0.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIK53387.1 - 0.035 14.7 1.2 0.16 12.6 0.6 2.2 1 1 0 2 2 2 0 FOXP coiled-coil domain Pkinase_Tyr PF07714.17 KIK53388.1 - 1.6e-29 103.0 0.0 1.9e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53388.1 - 1.8e-24 86.6 0.0 2.3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK53388.1 - 0.027 14.4 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_2 PF07719.17 KIK53390.1 - 0.013 15.6 0.2 0.033 14.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53390.1 - 0.015 15.1 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 KIK53392.1 - 1.6e-145 468.6 32.4 5.3e-12 46.1 0.2 12.2 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53392.1 - 2.2e-41 140.1 8.2 0.021 15.1 0.0 11.7 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK53392.1 - 1.8e-22 80.2 0.8 0.00012 22.0 0.0 5.3 1 1 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK53392.1 - 3.9e-18 65.5 6.5 0.3 10.0 0.0 11.1 1 1 11 12 12 12 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK53392.1 - 2.7e-17 63.1 0.5 1.1 8.5 0.1 10.2 5 5 6 11 11 11 5 WD40-like domain PD40 PF07676.12 KIK53392.1 - 2.4e-15 56.0 0.3 20 5.3 0.0 11.6 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK53392.1 - 1.1e-14 54.1 14.5 3.2 7.7 0.0 11.9 12 0 0 12 12 12 1 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KIK53392.1 - 4e-14 52.2 12.6 1.5 7.3 0.0 10.6 6 2 4 11 11 11 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK53392.1 - 2e-10 39.8 6.7 0.15 10.6 0.0 5.2 1 1 4 5 5 5 5 Cytochrome D1 heme domain NHL PF01436.21 KIK53392.1 - 6.9e-10 38.5 11.9 11 6.3 0.0 10.3 11 0 0 11 11 10 0 NHL repeat SdiA-regulated PF06977.11 KIK53392.1 - 4.1e-06 26.2 0.0 0.14 11.4 0.0 4.2 2 1 2 5 5 5 2 SdiA-regulated DsbC_N PF10411.9 KIK53392.1 - 4.9e-06 25.9 3.2 94 2.6 0.0 9.1 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus PQQ_3 PF13570.6 KIK53392.1 - 5.2e-06 26.8 23.3 6.1 7.5 0.1 10.5 6 4 5 11 11 11 1 PQQ-like domain Coatomer_WDAD PF04053.14 KIK53392.1 - 0.0001 21.5 3.7 0.0087 15.1 0.5 3.2 2 1 1 3 3 3 2 Coatomer WD associated region zf-LYAR PF08790.11 KIK53392.1 - 0.00069 19.5 2.5 1.8 8.5 0.1 3.9 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger Emaravirus_P4 PF16505.5 KIK53392.1 - 0.00092 18.3 0.0 16 4.4 0.0 5.4 7 1 0 7 7 7 0 P4 movement protein of Emaravirus, and the 30K superfamily Cuticle_4 PF15955.5 KIK53392.1 - 0.0012 19.5 2.3 1.4e+02 3.2 0.0 7.5 11 0 0 11 11 8 0 Cuticle protein Str_synth PF03088.16 KIK53392.1 - 0.0049 17.0 0.0 13 6.0 0.0 5.8 5 2 3 8 8 8 0 Strictosidine synthase CHAP PF05257.16 KIK53392.1 - 0.095 13.3 29.9 6.4 7.4 2.1 9.6 1 1 8 9 9 9 0 CHAP domain COPI_C PF06957.11 KIK53392.1 - 0.1 11.3 0.0 50 2.5 0.0 4.0 2 1 2 4 4 4 0 Coatomer (COPI) alpha subunit C-terminus Flu_B_M2 PF04772.12 KIK53392.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.8 2 0 0 2 2 1 0 Influenza B matrix protein 2 (BM2) DUF4596 PF15363.6 KIK53392.1 - 0.51 10.6 31.2 22 5.4 0.0 9.7 12 0 0 12 12 12 0 Domain of unknown function (DUF4596) Proteasome_A_N PF10584.9 KIK53392.1 - 0.91 9.3 17.5 48 3.8 0.1 8.5 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature zf-C2H2_4 PF13894.6 KIK53394.1 - 0.0057 17.4 3.8 0.0057 17.4 3.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK53394.1 - 0.0083 16.7 7.3 0.86 10.3 0.1 3.1 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK53394.1 - 0.015 15.7 4.5 0.015 15.7 4.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type SCIFF PF13165.6 KIK53396.1 - 0.038 13.9 0.6 0.079 12.9 0.6 1.6 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF Peptidase_C5 PF00770.18 KIK53397.1 - 0.032 13.9 0.3 0.039 13.6 0.3 1.1 1 0 0 1 1 1 0 Adenovirus endoprotease zf-C2H2 PF00096.26 KIK53401.1 - 0.00016 22.0 20.6 0.002 18.5 5.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF4428 PF14471.6 KIK53401.1 - 0.0065 16.4 1.4 0.011 15.7 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4428) zf-C2H2_4 PF13894.6 KIK53401.1 - 0.011 16.5 22.0 0.012 16.4 5.2 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger IBR PF01485.21 KIK53401.1 - 0.024 14.9 4.0 0.024 14.9 4.0 1.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_3rep PF18868.1 KIK53401.1 - 0.026 15.2 7.2 0.11 13.1 7.2 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KIK53401.1 - 0.053 13.8 4.9 0.077 13.3 4.8 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-RAG1 PF10426.9 KIK53401.1 - 0.1 12.7 3.1 0.73 10.0 0.1 2.6 2 1 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf_ZIC PF18366.1 KIK53401.1 - 0.13 12.4 2.9 0.47 10.6 0.4 2.7 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 KIK53401.1 - 0.64 10.4 9.7 1.4 9.3 9.3 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KIK53404.1 - 0.014 16.0 2.4 0.018 15.7 0.6 1.9 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIK53404.1 - 0.14 13.1 3.5 0.97 10.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK53408.1 - 0.0032 18.1 7.2 0.52 11.0 0.9 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIK53408.1 - 1.5 9.8 9.4 15 6.8 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger GCM PF03615.15 KIK53411.1 - 0.00015 21.7 2.1 0.00044 20.2 2.1 1.8 1 1 0 1 1 1 1 GCM motif protein WD40 PF00400.32 KIK53412.1 - 3e-53 176.6 22.8 1.3e-08 35.3 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53412.1 - 1.3e-15 57.5 7.2 0.066 13.5 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53412.1 - 4.7e-08 32.4 7.8 0.098 11.6 0.0 5.2 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK53412.1 - 3.4e-07 29.9 0.5 0.29 10.4 0.0 4.2 3 2 2 5 5 5 2 WD40-like domain Frtz PF11768.8 KIK53412.1 - 5.9e-05 21.6 0.2 0.23 9.7 0.0 3.8 1 1 3 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK53412.1 - 0.002 17.1 0.1 0.84 8.4 0.0 2.8 1 1 1 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KIK53412.1 - 0.011 14.4 1.4 0.28 9.7 0.1 2.7 1 1 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 KIK53412.1 - 0.021 13.5 4.7 5.7 5.5 0.1 3.6 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_3 PF15911.5 KIK53412.1 - 0.039 14.0 0.4 1.1e+02 2.9 0.0 4.4 4 2 1 5 5 5 0 WD domain, G-beta repeat DUF374 PF04028.13 KIK53412.1 - 0.083 12.5 0.7 8.1 6.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF374) DUF2019 PF09450.10 KIK53412.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) PQQ_3 PF13570.6 KIK53412.1 - 1.2 9.7 4.4 26 5.5 0.1 4.1 5 0 0 5 5 5 0 PQQ-like domain zf-CCHC PF00098.23 KIK53416.1 - 3.8e-05 23.6 3.8 6.2e-05 22.9 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KIK53416.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein BAR_3 PF16746.5 KIK53417.1 - 0.017 14.8 4.1 0.25 11.0 0.9 2.2 2 0 0 2 2 2 0 BAR domain of APPL family TSNAXIP1_N PF15739.5 KIK53417.1 - 0.024 15.0 0.7 0.051 13.9 0.7 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Spc7 PF08317.11 KIK53418.1 - 0.0013 17.7 4.7 0.002 17.0 4.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FAM76 PF16046.5 KIK53418.1 - 0.0037 16.7 2.2 0.0037 16.7 2.2 1.9 2 0 0 2 2 2 1 FAM76 protein Sec2p PF06428.11 KIK53418.1 - 0.0063 16.5 1.5 0.0063 16.5 1.5 2.8 2 1 1 3 3 3 2 GDP/GTP exchange factor Sec2p Peptidase_S49_N PF08496.10 KIK53418.1 - 0.0098 16.0 1.1 0.016 15.2 1.1 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal YqjK PF13997.6 KIK53418.1 - 0.11 12.8 0.3 0.31 11.3 0.3 1.8 1 0 0 1 1 1 0 YqjK-like protein CCDC-167 PF15188.6 KIK53418.1 - 0.14 12.5 10.1 0.57 10.6 10.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Spc42p PF11544.8 KIK53418.1 - 0.17 11.9 5.7 2.3 8.3 0.6 2.8 3 0 0 3 3 3 0 Spindle pole body component Spc42p Fib_alpha PF08702.10 KIK53418.1 - 0.19 11.9 1.9 0.35 11.0 1.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.6 KIK53418.1 - 0.47 10.2 7.7 0.16 11.7 4.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FapA PF03961.13 KIK53418.1 - 3 6.3 4.6 4.6 5.7 4.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KIK53418.1 - 4.6 7.3 4.8 16 5.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KIK53418.1 - 6.8 6.6 10.7 9 6.2 0.2 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase OmpH PF03938.14 KIK53418.1 - 8.8 6.7 8.9 35 4.7 8.9 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4219 PF13961.6 KIK53421.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Peptidase_C12 PF01088.21 KIK53422.1 - 0.00077 19.3 0.4 0.0014 18.5 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1128 PF06569.11 KIK53422.1 - 0.16 11.9 1.6 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) GATase_7 PF13537.6 KIK53424.1 - 0.033 14.1 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase domain GFA PF04828.14 KIK53425.1 - 2e-16 60.1 0.1 3e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 KIK53425.1 - 0.81 9.5 4.9 0.59 9.9 2.5 1.9 2 0 0 2 2 2 0 CSL zinc finger IBR PF01485.21 KIK53426.1 - 2e-12 47.2 48.6 2.1e-07 31.1 6.1 4.6 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain IBR PF01485.21 KIK53427.1 - 1.3e-17 63.8 37.1 6.1e-09 36.0 3.8 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain Branch PF02485.21 KIK53427.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme CoA_transf_3 PF02515.17 KIK53428.1 - 1.2e-109 366.8 0.0 1.4e-109 366.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III IBR PF01485.21 KIK53429.1 - 8.1e-14 51.6 33.0 2e-07 31.1 9.4 3.2 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain Alpha-L-AF_C PF06964.12 KIK53431.1 - 1.9e-32 112.7 0.3 5.4e-32 111.2 0.1 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain NAR2 PF16974.5 KIK53431.1 - 1.2 8.5 4.4 0.25 10.7 0.1 2.0 3 0 0 3 3 3 0 High-affinity nitrate transporter accessory Methyltransf_2 PF00891.18 KIK53432.1 - 1.5e-23 83.2 0.0 1.1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain DUF1830 PF08865.11 KIK53432.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) MARVEL PF01284.23 KIK53434.1 - 0.0047 17.0 22.1 0.0086 16.1 22.1 1.4 1 1 0 1 1 1 1 Membrane-associating domain Hanta_G2 PF01561.16 KIK53434.1 - 4.7 5.7 7.2 2.2 6.8 0.4 2.1 2 0 0 2 2 2 0 Hantavirus glycoprotein G2 G-alpha PF00503.20 KIK53435.1 - 2e-80 270.6 0.1 2.3e-80 270.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK53435.1 - 0.00018 21.0 0.3 0.0034 16.9 0.2 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK53436.1 - 2.4e-68 230.9 0.0 1.5e-66 224.9 0.0 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK53436.1 - 8.3e-07 28.6 0.0 3.6e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK53437.1 - 5.2e-78 262.7 0.1 6e-78 262.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK53437.1 - 2.1e-05 24.0 0.0 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GST_N_3 PF13417.6 KIK53439.1 - 2.9e-10 40.4 0.1 5.8e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK53439.1 - 2.7e-08 34.0 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK53439.1 - 2.1e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK53439.1 - 0.024 14.9 0.1 0.18 12.2 0.1 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIK53439.1 - 0.14 12.9 0.1 3.3 8.5 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain DUF2062 PF09835.9 KIK53440.1 - 0.047 13.6 0.1 0.048 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Aim21 PF11489.8 KIK53443.1 - 0.014 14.4 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 Phage_TAC_2 PF06894.11 KIK53443.1 - 0.08 12.7 1.0 0.11 12.3 1.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G ATG_C PF09333.11 KIK53443.1 - 0.12 12.7 1.2 2.3 8.6 0.1 2.8 1 1 2 3 3 3 0 Autophagy-related protein C terminal domain YlqD PF11068.8 KIK53443.1 - 0.15 12.5 5.0 0.26 11.7 5.0 1.4 1 0 0 1 1 1 0 YlqD protein F-box-like PF12937.7 KIK53448.1 - 0.011 15.6 0.1 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like Ycf15 PF10705.9 KIK53450.1 - 0.15 12.2 0.1 7.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative AAA PF00004.29 KIK53451.1 - 1.7e-12 47.9 0.0 2.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Capsid_VP7 PF17071.5 KIK53451.1 - 0.062 12.6 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Outer capsid protein VP7 CxC4 PF18717.1 KIK53453.1 - 2.4e-41 140.7 0.7 4.1e-41 139.9 0.0 1.8 3 0 0 3 3 3 1 CxC4 like cysteine cluster associated with KDZ transposases Rep_fac-A_3 PF08661.11 KIK53455.1 - 1.4e-07 31.8 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Dak1 PF02733.17 KIK53456.1 - 1.9e-94 316.0 0.6 1.3e-68 231.2 0.0 2.1 2 0 0 2 2 2 2 Dak1 domain Dak2 PF02734.17 KIK53456.1 - 5.8e-34 117.5 0.0 2.9e-23 82.6 0.0 2.7 2 1 0 2 2 2 2 DAK2 domain AAA_30 PF13604.6 KIK53458.1 - 0.00092 19.0 0.0 0.00096 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK53458.1 - 0.003 17.9 0.0 0.0033 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK53458.1 - 0.0045 16.2 0.1 0.0045 16.2 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase Guanylate_kin PF00625.21 KIK53458.1 - 0.0088 15.8 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase Helicase_RecD PF05127.14 KIK53458.1 - 0.028 14.3 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_16 PF13191.6 KIK53458.1 - 0.21 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Dak2 PF02734.17 KIK53459.1 - 8.9e-19 68.0 0.0 1.5e-18 67.3 0.0 1.3 1 1 0 1 1 1 1 DAK2 domain Dak1 PF02733.17 KIK53460.1 - 1.6e-10 40.4 0.0 1.6e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain Dak1 PF02733.17 KIK53461.1 - 1.5e-20 73.3 0.4 1.7e-20 73.2 0.4 1.0 1 0 0 1 1 1 1 Dak1 domain Cpn60_TCP1 PF00118.24 KIK53462.1 - 8e-43 146.8 0.0 1e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4437 PF14499.6 KIK53462.1 - 0.044 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) MUG113 PF13455.6 KIK53465.1 - 1.8e-05 25.3 0.0 3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK53465.1 - 0.017 15.7 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 T5orf172 domain KDZ PF18758.1 KIK53466.1 - 2.7e-05 23.9 0.7 3.1e-05 23.7 0.7 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 KIK53467.1 - 3.4e-46 156.3 0.4 6.9e-46 155.3 0.4 1.5 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases FHA PF00498.26 KIK53475.1 - 4.3e-10 39.8 0.0 6.7e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK53475.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Trp_repressor PF01371.19 KIK53480.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Trp repressor protein Abhydrolase_1 PF00561.20 KIK53481.1 - 5.6e-18 65.5 0.0 1e-17 64.6 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold EHN PF06441.12 KIK53481.1 - 8.1e-08 32.6 0.0 1.4e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.7 KIK53481.1 - 0.0035 18.0 1.4 0.0057 17.3 1.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family UbiA PF01040.18 KIK53482.1 - 1.2e-40 139.4 16.2 1.6e-40 139.1 16.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2721 PF11026.8 KIK53482.1 - 0.0033 17.3 0.4 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) p450 PF00067.22 KIK53483.1 - 5.6e-59 200.1 0.0 6.8e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KIK53484.1 - 9.1e-20 70.8 0.0 4.9e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain CUT PF02376.15 KIK53484.1 - 0.015 15.5 1.1 7.7 6.8 0.4 2.4 2 0 0 2 2 2 0 CUT domain MarR_2 PF12802.7 KIK53484.1 - 0.16 11.9 0.0 0.57 10.1 0.0 1.9 1 0 0 1 1 1 0 MarR family p450 PF00067.22 KIK53485.1 - 5.1e-67 226.6 0.0 1.8e-66 224.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-RVT PF13966.6 KIK53486.1 - 0.00039 21.1 0.5 0.00062 20.4 0.5 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_Tnp_4 PF13359.6 KIK53488.1 - 2.8e-15 56.3 0.0 9.1e-14 51.4 0.0 2.7 2 1 0 2 2 2 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 KIK53492.1 - 1e-05 25.7 0.1 4.7e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK53492.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) THDPS_N_2 PF14805.6 KIK53493.1 - 0.006 16.8 0.2 0.011 15.9 0.2 1.4 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal RVP_2 PF08284.11 KIK53493.1 - 0.0084 15.9 0.0 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease AAA_lid_11 PF18198.1 KIK53496.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain GMC_oxred_N PF00732.19 KIK53500.1 - 1.3e-60 205.3 0.0 1.7e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK53500.1 - 3.5e-35 121.6 0.0 5.9e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK53500.1 - 5e-05 22.6 0.4 0.00096 18.3 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK53500.1 - 7.6e-05 22.1 0.1 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK53500.1 - 8.8e-05 21.9 0.1 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK53500.1 - 0.00053 19.1 0.1 0.0015 17.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK53500.1 - 0.003 17.7 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK53500.1 - 0.003 17.2 0.2 0.069 12.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK53500.1 - 0.02 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family RmuC PF02646.16 KIK53510.1 - 0.00022 20.5 2.1 0.00025 20.3 2.1 1.3 1 0 0 1 1 1 1 RmuC family YabA PF06156.13 KIK53510.1 - 0.0026 18.4 1.2 0.0053 17.4 1.2 1.6 1 1 0 1 1 1 1 Initiation control protein YabA ZapB PF06005.12 KIK53510.1 - 0.0075 16.7 3.2 0.0075 16.7 3.2 1.7 1 1 1 2 2 2 1 Cell division protein ZapB CENP-F_leu_zip PF10473.9 KIK53510.1 - 0.075 13.1 6.0 0.13 12.2 6.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RET_CLD1 PF17756.1 KIK53512.1 - 0.027 14.7 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 RET Cadherin like domain 1 PapJ PF14855.6 KIK53513.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone BORCS6 PF10157.9 KIK53514.1 - 0.042 14.1 0.0 0.074 13.3 0.0 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 LRS4 PF10422.9 KIK53515.1 - 0.6 9.6 8.4 0.97 8.9 8.4 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF641 PF04859.12 KIK53515.1 - 0.62 10.4 6.0 2.8 8.3 6.1 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 KIK53515.1 - 3.7 8.1 5.9 10 6.6 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF648 PF04890.13 KIK53516.1 - 0.03 14.1 0.5 0.043 13.6 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DDE_Tnp_4 PF13359.6 KIK53517.1 - 1.2e-19 70.5 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease GMC_oxred_N PF00732.19 KIK53520.1 - 1.1e-72 245.0 0.0 1.4e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK53520.1 - 6.7e-32 111.0 0.4 1.5e-31 109.8 0.4 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK53520.1 - 3e-05 24.2 0.9 7.5e-05 22.9 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK53520.1 - 4e-05 22.8 0.1 5.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK53520.1 - 6.4e-05 22.2 1.3 0.049 12.7 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIK53520.1 - 0.00093 18.9 1.8 0.0093 15.6 1.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK53520.1 - 0.0022 17.3 0.1 0.0032 16.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK53520.1 - 0.0025 17.1 0.1 0.0058 15.9 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK53520.1 - 0.0033 16.7 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK53520.1 - 0.031 13.0 0.2 0.05 12.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KIK53520.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Abhydrolase_1 PF00561.20 KIK53521.1 - 9.2e-11 41.9 0.0 7.9e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK53521.1 - 1.5e-06 29.0 0.1 2.2e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK53521.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cu_amine_oxid PF01179.20 KIK53522.1 - 6e-127 424.0 5.1 9.1e-127 423.4 5.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KIK53522.1 - 3.8e-26 90.7 0.8 7.9e-26 89.6 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KIK53522.1 - 4.2e-08 33.3 0.0 8.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain NAD_binding_4 PF07993.12 KIK53523.1 - 4.2e-42 144.1 0.0 5.9e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK53523.1 - 6.1e-27 94.3 0.0 1.1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK53523.1 - 5.4e-09 35.9 0.0 9.2e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK53523.1 - 9.5e-05 22.7 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KIK53523.1 - 9.6e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIK53523.1 - 0.00072 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_2 PF00891.18 KIK53524.1 - 4.5e-24 84.9 0.1 1.8e-22 79.7 0.1 2.3 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KIK53524.1 - 0.026 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Trp_halogenase PF04820.14 KIK53525.1 - 3.2e-30 105.4 2.2 5.5e-13 48.6 0.0 3.3 3 1 1 4 4 4 3 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK53525.1 - 5.4e-10 39.0 0.1 0.00037 19.8 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 KIK53525.1 - 2.7e-07 30.1 0.0 3.6e-05 23.1 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK53525.1 - 4.6e-05 23.2 0.1 0.0025 17.5 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK53525.1 - 8.1e-05 22.1 0.0 0.00021 20.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK53525.1 - 9e-05 22.6 0.1 9e-05 22.6 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK53525.1 - 0.00013 22.4 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK53525.1 - 0.0005 18.9 0.0 0.0061 15.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KIK53525.1 - 0.00063 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK53525.1 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIK53525.1 - 0.018 14.1 0.6 0.55 9.2 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KIK53525.1 - 0.076 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIK53525.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIK53525.1 - 0.1 12.5 0.1 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hydrolase_4 PF12146.8 KIK53529.1 - 5.6e-07 29.1 0.0 8.8e-07 28.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK53529.1 - 1e-06 28.6 0.1 4.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK53529.1 - 2.6e-05 24.9 0.0 4.2e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK53529.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Pox_mRNA-cap PF03341.13 KIK53529.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit ChAPs PF09295.10 KIK53529.1 - 0.092 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) HEPN_DZIP3 PF18738.1 KIK53533.1 - 0.022 14.5 0.3 0.032 14.0 0.3 1.1 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Plavaka PF18759.1 KIK53535.1 - 3.1e-09 36.5 0.0 3.4e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase zf-CCHC PF00098.23 KIK53537.1 - 0.00017 21.5 3.8 0.00036 20.5 3.8 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF648 PF04890.13 KIK53538.1 - 0.019 14.7 0.4 0.027 14.2 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Peptidase_S49_N PF08496.10 KIK53539.1 - 0.01 15.9 0.9 0.01 15.9 0.9 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK53539.1 - 0.012 16.1 9.4 0.023 15.1 9.4 1.5 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KIK53539.1 - 0.015 14.2 12.9 0.025 13.5 12.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KIK53539.1 - 0.017 15.0 12.2 0.031 14.1 12.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Bacillus_HBL PF05791.11 KIK53539.1 - 0.018 14.9 2.0 0.43 10.4 1.0 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HMMR_N PF15905.5 KIK53539.1 - 0.041 13.4 10.8 0.063 12.7 10.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 KIK53539.1 - 0.15 11.9 8.9 0.58 10.1 0.4 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 KIK53539.1 - 0.17 11.9 17.0 0.17 11.9 7.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 KIK53539.1 - 0.3 11.8 5.8 1.8 9.3 0.9 2.5 2 0 0 2 2 2 0 Initiation control protein YabA LRS4 PF10422.9 KIK53539.1 - 0.33 10.5 8.8 0.58 9.7 8.8 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4407 PF14362.6 KIK53539.1 - 0.34 10.2 8.3 0.5 9.7 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KIK53539.1 - 0.6 10.6 22.7 2.8 8.5 8.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec2p PF06428.11 KIK53539.1 - 0.72 9.9 11.8 0.12 12.3 2.3 2.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 KIK53539.1 - 0.99 9.6 18.1 8.3 6.6 4.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 KIK53539.1 - 1 8.6 12.8 0.15 11.3 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KIK53539.1 - 1.2 9.6 14.1 0.64 10.4 2.2 3.4 1 1 3 4 4 4 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 KIK53539.1 - 2.6 7.8 9.0 2.8 7.7 1.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF641 PF04859.12 KIK53539.1 - 6.4 7.1 9.6 1.9 8.8 2.0 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BRE1 PF08647.11 KIK53539.1 - 6.9 6.8 11.6 13 5.9 1.0 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FAM76 PF16046.5 KIK53541.1 - 0.003 16.9 1.4 0.0043 16.4 1.4 1.2 1 0 0 1 1 1 1 FAM76 protein LRS4 PF10422.9 KIK53541.1 - 0.011 15.3 5.8 0.011 15.3 5.8 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 KASH_CCD PF14662.6 KIK53541.1 - 0.015 15.1 7.2 0.023 14.5 7.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PKcGMP_CC PF16808.5 KIK53541.1 - 0.068 13.0 8.0 0.48 10.3 0.5 2.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK53541.1 - 0.11 12.6 0.4 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec2p PF06428.11 KIK53541.1 - 0.16 11.9 7.7 0.15 12.1 3.6 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Cnn_1N PF07989.11 KIK53541.1 - 0.28 11.4 5.3 1.1 9.4 0.7 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 KIK53541.1 - 0.47 10.8 8.2 1.9 8.9 0.7 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF3450 PF11932.8 KIK53541.1 - 0.79 9.0 8.9 0.088 12.1 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 KIK53541.1 - 0.95 9.8 6.9 4 7.8 5.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ABC_tran_Xtn PF12848.7 KIK53541.1 - 0.95 9.5 3.5 2.5 8.2 3.5 1.6 1 0 0 1 1 1 0 ABC transporter Phage_GP20 PF06810.11 KIK53541.1 - 1.7 8.4 6.7 2.7 7.8 0.8 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.8 KIK53541.1 - 8.1 6.5 12.3 29 4.8 2.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4660 PF15559.6 KIK53542.1 - 0.13 12.6 0.4 0.22 11.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) BAR_2 PF10455.9 KIK53543.1 - 0.0091 15.2 0.4 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Tropomyosin PF00261.20 KIK53543.1 - 0.015 14.6 1.1 0.019 14.3 1.1 1.0 1 0 0 1 1 1 0 Tropomyosin Phage_TAC_5 PF08890.11 KIK53543.1 - 0.021 14.8 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC DUF745 PF05335.13 KIK53543.1 - 0.025 14.3 3.3 0.62 9.8 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Wx5_PLAF3D7 PF09688.10 KIK53543.1 - 0.061 13.3 0.3 0.086 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Fib_alpha PF08702.10 KIK53543.1 - 0.12 12.6 3.8 0.16 12.1 0.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 KIK53543.1 - 0.17 12.1 3.8 0.22 11.7 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FliJ PF02050.16 KIK53543.1 - 0.25 11.6 5.1 1 9.6 3.9 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein FlxA PF14282.6 KIK53544.1 - 6.4 6.8 6.2 14 5.7 2.2 2.2 2 0 0 2 2 2 0 FlxA-like protein CxC1 PF18802.1 KIK53545.1 - 0.00074 19.6 0.3 0.001 19.2 0.3 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIK53545.1 - 0.00099 19.2 0.2 0.0011 19.1 0.2 1.1 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Spc7 PF08317.11 KIK53546.1 - 0.0066 15.4 4.9 0.0098 14.8 4.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 KIK53546.1 - 0.0079 15.8 3.8 0.033 13.8 0.0 2.1 1 1 1 2 2 2 1 Intermediate filament protein COG4 PF08318.12 KIK53546.1 - 0.063 12.3 0.3 0.11 11.6 0.3 1.4 1 0 0 1 1 1 0 COG4 transport protein Lebercilin PF15619.6 KIK53546.1 - 0.098 12.3 6.2 0.2 11.3 6.2 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SPATA1_C PF15743.5 KIK53546.1 - 0.11 12.6 1.1 0.37 10.8 0.0 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus ADIP PF11559.8 KIK53546.1 - 0.13 12.4 3.4 0.16 12.0 1.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YscO PF07321.12 KIK53546.1 - 1.2 9.1 9.6 0.1 12.6 1.2 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO DUF5471 PF17565.2 KIK53547.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5471) DUF745 PF05335.13 KIK53547.1 - 0.25 11.0 4.5 0.17 11.6 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Retrotrans_gag PF03732.17 KIK53548.1 - 1.4e-05 25.3 0.0 4.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Ste5 PF11610.8 KIK53550.1 - 5.2 7.0 11.3 0.71 9.8 0.1 2.7 3 0 0 3 3 3 0 Scaffold protein Ste5, Fus3-binding region WD40 PF00400.32 KIK53556.1 - 7.9e-112 362.0 63.9 1.9e-10 41.1 0.3 13.9 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53556.1 - 2.8e-23 82.0 17.5 0.03 14.6 0.0 11.6 1 1 10 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53556.1 - 4.4e-14 51.7 0.4 0.68 8.2 0.0 9.2 5 2 4 10 10 10 5 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53556.1 - 8.4e-13 48.3 4.0 0.49 9.7 0.0 8.2 5 2 3 9 9 9 3 WD40-like domain Ge1_WD40 PF16529.5 KIK53556.1 - 8.5e-12 44.7 16.3 0.0069 15.4 0.0 9.7 1 1 8 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK53556.1 - 3.2e-09 36.9 0.0 8.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK53556.1 - 2.4e-07 30.2 0.1 2.8e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KIK53556.1 - 1.6e-05 25.4 0.1 6.7e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KIK53556.1 - 0.00082 19.7 0.1 0.0083 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK53556.1 - 0.0015 18.8 0.0 0.0057 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain Cytochrom_D1 PF02239.16 KIK53556.1 - 0.0022 16.6 16.4 0.64 8.5 0.1 5.1 2 2 2 5 5 5 3 Cytochrome D1 heme domain ABC_tran PF00005.27 KIK53556.1 - 0.0026 18.3 0.0 0.0094 16.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 KIK53556.1 - 0.0034 17.8 0.0 0.009 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1258 PF06869.12 KIK53556.1 - 0.0066 16.0 0.2 3 7.2 0.0 4.3 5 1 1 6 6 6 1 Protein of unknown function (DUF1258) PD40 PF07676.12 KIK53556.1 - 0.014 15.3 16.5 31 4.7 0.0 8.9 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.22 KIK53556.1 - 0.028 14.8 1.8 0.37 11.2 0.1 3.9 4 1 1 5 5 3 0 RNA helicase DUF4777 PF16007.5 KIK53556.1 - 0.21 11.9 0.2 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) WD40 PF00400.32 KIK53558.1 - 6.4e-109 352.8 59.5 2.6e-10 40.7 0.1 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53558.1 - 1.2e-24 86.4 17.9 0.18 12.1 0.0 11.6 1 1 10 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53558.1 - 4e-16 58.4 0.6 0.16 10.2 0.0 8.1 3 3 6 9 9 9 6 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK53558.1 - 4.7e-14 52.1 12.4 0.045 12.7 0.0 9.2 2 2 6 9 9 9 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK53558.1 - 3e-11 43.2 2.7 0.0074 15.6 0.0 6.6 4 2 2 8 8 8 2 WD40-like domain NACHT PF05729.12 KIK53558.1 - 2.1e-09 37.5 0.0 4.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Me-amine-dh_H PF06433.11 KIK53558.1 - 3.9e-08 32.6 0.4 0.2 10.5 0.0 5.3 2 2 3 6 6 6 3 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 KIK53558.1 - 1.5e-06 27.9 0.8 32 4.7 0.0 8.9 12 0 0 12 12 12 0 PQQ enzyme repeat PD40 PF07676.12 KIK53558.1 - 2.8e-05 23.9 4.1 80 3.3 0.0 8.2 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat NB-ARC PF00931.22 KIK53558.1 - 3e-05 23.3 0.3 0.00015 21.0 0.1 2.2 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KIK53558.1 - 5.1e-05 23.7 0.0 0.00018 22.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KIK53558.1 - 9.3e-05 21.1 9.0 0.2 10.2 0.2 4.5 1 1 3 5 5 5 2 Cytochrome D1 heme domain DUF1258 PF06869.12 KIK53558.1 - 0.0053 16.3 0.3 12 5.3 0.0 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) AAA PF00004.29 KIK53558.1 - 0.0063 16.9 0.0 0.019 15.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK53558.1 - 0.031 14.8 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KIK53558.1 - 0.04 14.3 0.1 0.39 11.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KIK53558.1 - 0.046 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK53558.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain YadA_stalk PF05662.14 KIK53558.1 - 0.44 10.9 1.7 25 5.3 0.0 3.7 3 1 1 4 4 4 0 Coiled stalk of trimeric autotransporter adhesin CHAP PF05257.16 KIK53558.1 - 6.7 7.4 31.5 8.9 7.0 1.3 8.5 1 1 4 6 6 6 0 CHAP domain WD40 PF00400.32 KIK53560.1 - 6.8e-29 99.5 2.2 3.7e-07 30.7 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53560.1 - 0.00045 20.5 0.0 1.6 9.1 0.0 3.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53560.1 - 0.011 15.1 0.0 0.41 9.9 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain Frtz PF11768.8 KIK53560.1 - 0.058 11.7 0.0 3.6 5.8 0.0 3.0 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 KIK53561.1 - 6.9e-06 25.6 0.0 2e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53561.1 - 0.003 16.9 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 KIK53563.1 - 1.7e-106 345.1 52.6 8.4e-11 42.3 0.0 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53563.1 - 6.8e-29 100.0 12.4 0.0033 17.7 0.0 10.3 1 1 10 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53563.1 - 6.6e-16 57.7 0.4 0.14 10.4 0.0 8.1 3 2 3 7 7 7 5 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53563.1 - 7.6e-15 55.0 3.4 0.26 10.6 0.1 7.1 5 2 1 6 6 6 6 WD40-like domain Ge1_WD40 PF16529.5 KIK53563.1 - 5.6e-13 48.5 18.9 0.1 11.6 0.1 9.9 1 1 9 10 10 10 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53563.1 - 3.2e-09 36.5 15.1 2.5 8.2 0.0 9.3 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.11 KIK53563.1 - 4e-09 35.8 1.8 0.16 10.8 0.0 4.9 2 2 2 5 5 5 3 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 KIK53563.1 - 1.3e-08 34.7 19.1 0.0013 18.4 3.3 5.1 1 1 1 4 4 4 4 PQQ-like domain PQQ PF01011.21 KIK53563.1 - 1.1e-07 31.4 1.9 7.6 6.7 0.0 7.7 9 0 0 9 9 9 1 PQQ enzyme repeat NAGPA PF09992.9 KIK53563.1 - 0.00019 21.7 1.8 15 5.8 0.0 5.2 2 2 1 4 4 4 0 Phosphodiester glycosidase PQQ_3 PF13570.6 KIK53563.1 - 0.00036 20.9 18.9 25 5.5 0.1 9.4 10 1 1 11 11 11 0 PQQ-like domain PALB2_WD40 PF16756.5 KIK53563.1 - 0.0017 17.3 13.5 2.1 7.2 0.1 6.7 3 2 4 8 8 8 2 Partner and localizer of BRCA2 WD40 domain DUF4242 PF14026.6 KIK53563.1 - 0.0026 17.9 0.0 13 6.0 0.0 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF4242) CHAP PF05257.16 KIK53563.1 - 0.02 15.5 26.6 7.5 7.2 0.1 8.9 1 1 8 10 10 10 0 CHAP domain Nup160 PF11715.8 KIK53563.1 - 0.064 11.9 11.2 7.5 5.1 0.0 5.8 1 1 5 8 8 8 0 Nucleoporin Nup120/160 DUF2019 PF09450.10 KIK53563.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) LPD7 PF18821.1 KIK53563.1 - 0.22 11.7 0.5 19 5.5 0.0 4.2 4 1 0 4 4 4 0 Large polyvalent protein-associated domain 7 Peptidase_S9_N PF02897.15 KIK53563.1 - 0.28 9.9 1.6 9 5.0 0.0 3.3 4 0 0 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Robl_LC7 PF03259.17 KIK53563.1 - 0.41 10.5 3.2 3.2 7.6 0.0 4.0 6 0 0 6 6 6 0 Roadblock/LC7 domain WD40 PF00400.32 KIK53567.1 - 2.2e-125 404.9 68.4 3.4e-10 40.4 0.3 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53567.1 - 1.2e-32 112.0 20.6 0.0032 17.7 0.1 13.7 1 1 13 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53567.1 - 5.7e-18 64.5 1.5 0.78 8.0 0.0 10.8 5 2 7 12 12 12 7 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK53567.1 - 1.9e-15 57.1 22.0 4.9e-06 26.3 3.8 5.3 1 1 3 4 4 4 4 PQQ-like domain Ge1_WD40 PF16529.5 KIK53567.1 - 7.6e-11 41.5 18.9 0.06 12.3 0.0 10.5 1 1 11 13 13 13 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK53567.1 - 1.8e-10 40.6 3.6 0.26 10.6 0.0 7.6 4 2 3 9 9 9 2 WD40-like domain NACHT PF05729.12 KIK53567.1 - 2.1e-09 37.5 0.0 5.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK53567.1 - 4.5e-07 29.3 0.1 2.1e-06 27.1 0.1 2.1 2 1 0 2 2 2 1 NB-ARC domain Cytochrom_D1 PF02239.16 KIK53567.1 - 2.6e-06 26.2 11.4 0.31 9.5 0.2 5.6 2 2 3 6 6 6 5 Cytochrome D1 heme domain AAA_16 PF13191.6 KIK53567.1 - 1.9e-05 25.1 0.0 4.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK53567.1 - 0.00015 22.1 0.1 0.0096 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF1258 PF06869.12 KIK53567.1 - 0.00053 19.6 1.0 0.94 8.9 0.0 4.4 4 1 1 5 5 5 1 Protein of unknown function (DUF1258) ABC_tran PF00005.27 KIK53567.1 - 0.0026 18.3 0.0 0.0084 16.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KIK53567.1 - 0.003 17.8 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK53567.1 - 0.0039 17.6 0.0 0.0095 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK53567.1 - 0.0062 16.9 0.5 0.35 11.3 0.1 4.0 3 0 0 3 3 3 1 RNA helicase PD40 PF07676.12 KIK53567.1 - 0.018 15.0 13.9 58 3.8 0.0 9.0 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat SecA_PP_bind PF01043.20 KIK53567.1 - 0.07 13.8 0.1 26 5.5 0.0 4.7 6 0 0 6 6 5 0 SecA preprotein cross-linking domain WD40 PF00400.32 KIK53570.1 - 2.9e-46 154.5 24.7 7.4e-10 39.3 0.0 6.0 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53570.1 - 9.4e-14 51.5 2.9 0.0013 19.0 0.0 4.8 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53570.1 - 1.6e-07 30.1 0.0 0.23 9.8 0.0 4.4 2 1 1 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK53570.1 - 3.9e-07 29.4 1.0 0.013 14.5 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53570.1 - 2.2e-05 24.3 3.1 5 7.2 0.0 4.7 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.11 KIK53570.1 - 0.00051 19.0 0.1 0.013 14.4 0.0 2.3 1 1 2 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) PALB2_WD40 PF16756.5 KIK53570.1 - 0.00052 19.0 3.5 0.7 8.7 0.3 3.8 1 1 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain DUF1258 PF06869.12 KIK53570.1 - 0.0021 17.6 0.1 0.66 9.4 0.0 3.4 1 1 3 4 4 4 1 Protein of unknown function (DUF1258) WD40_like PF17005.5 KIK53570.1 - 0.012 15.0 0.5 8.9 5.5 0.0 3.4 2 1 3 5 5 5 0 WD40-like domain PQQ_2 PF13360.6 KIK53570.1 - 0.024 14.2 2.9 0.042 13.4 0.8 2.0 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 KIK53570.1 - 0.039 13.9 0.0 1e+02 3.1 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat SLH PF00395.20 KIK53570.1 - 0.091 12.8 0.0 40 4.3 0.0 3.9 5 0 0 5 5 5 0 S-layer homology domain WD40 PF00400.32 KIK53571.1 - 3.5e-46 154.2 14.4 6e-10 39.6 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53571.1 - 1.5e-13 50.9 2.4 0.028 14.7 0.0 5.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53571.1 - 3.7e-09 36.0 1.1 0.3 10.0 0.0 5.0 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK53571.1 - 1.6e-05 23.4 0.1 0.27 9.5 0.0 3.1 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53571.1 - 9.8e-05 21.8 0.0 0.0091 15.4 0.0 2.8 2 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 KIK53571.1 - 0.00019 21.3 0.2 7.6 6.6 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK53571.1 - 0.017 13.7 1.3 0.17 10.4 0.1 2.6 1 1 1 3 3 3 0 Cytochrome D1 heme domain Adeno_E1B_19K PF01691.16 KIK53571.1 - 0.037 13.6 0.0 1.9 8.1 0.0 2.6 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen Nup160 PF11715.8 KIK53571.1 - 0.06 12.0 3.9 0.61 8.7 0.4 3.2 1 1 1 3 3 3 0 Nucleoporin Nup120/160 VID27 PF08553.10 KIK53571.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 KIK53571.1 - 0.12 11.2 5.5 5.8 5.7 0.2 3.5 1 1 4 5 5 5 0 Partner and localizer of BRCA2 WD40 domain DUF5570 PF17731.1 KIK53571.1 - 0.12 12.4 2.0 0.28 11.3 0.7 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5570) WD40 PF00400.32 KIK53572.1 - 1.4e-09 38.4 0.3 6.6e-05 23.6 0.2 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 KIK53573.1 - 1.5e-112 364.2 64.6 2.6e-09 37.6 0.2 13.9 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53573.1 - 3.6e-24 84.9 17.6 0.016 15.5 0.1 11.9 1 1 12 13 13 13 7 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53573.1 - 9.1e-14 50.7 4.8 0.074 11.4 0.0 9.6 3 2 9 12 12 12 4 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53573.1 - 2.7e-10 40.1 10.9 0.45 9.8 0.1 7.3 5 1 3 8 8 8 4 WD40-like domain PQQ_2 PF13360.6 KIK53573.1 - 2.2e-09 37.2 25.0 0.0012 18.5 6.5 5.4 2 2 1 3 3 3 3 PQQ-like domain eIF2A PF08662.11 KIK53573.1 - 4.9e-09 36.4 0.6 0.00023 21.1 0.0 5.1 2 2 3 5 5 5 1 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 KIK53573.1 - 1.8e-07 31.2 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK53573.1 - 1.4e-06 27.7 0.1 1.6e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain Ge1_WD40 PF16529.5 KIK53573.1 - 1.9e-05 23.8 19.0 0.81 8.6 0.0 9.2 1 1 9 11 11 11 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53573.1 - 7.2e-05 22.6 6.4 22 5.1 0.0 8.5 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK53573.1 - 7.7e-05 23.1 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK53573.1 - 0.0003 20.6 1.3 1.4e+02 2.6 0.0 8.0 10 0 0 10 10 9 0 PQQ enzyme repeat AAA_22 PF13401.6 KIK53573.1 - 0.00065 20.0 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK53573.1 - 0.0015 19.0 0.0 0.0046 17.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 KIK53573.1 - 0.0033 17.8 0.0 0.0073 16.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK53573.1 - 0.0058 17.0 1.0 0.4 11.1 0.0 4.3 3 1 1 4 4 4 1 RNA helicase AAA_19 PF13245.6 KIK53573.1 - 0.0089 16.4 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK53573.1 - 0.099 13.2 0.0 0.5 10.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KIK53573.1 - 0.15 11.8 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain CHAP PF05257.16 KIK53573.1 - 0.29 11.7 30.5 9.9 6.8 0.7 8.6 1 1 6 8 8 8 0 CHAP domain WD40 PF00400.32 KIK53577.1 - 3e-112 363.3 62.9 4.5e-10 39.9 0.4 14.9 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53577.1 - 2.4e-28 98.2 20.7 0.0023 18.2 0.0 12.2 1 1 12 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK53577.1 - 3e-15 56.6 4.2 0.08 12.8 0.0 6.2 2 2 5 7 7 7 6 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK53577.1 - 8.3e-15 54.9 7.0 0.14 11.4 0.0 7.8 6 3 1 7 7 7 4 WD40-like domain Frtz PF11768.8 KIK53577.1 - 3.7e-13 48.7 1.2 0.38 9.0 0.0 7.8 2 2 5 8 8 8 6 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK53577.1 - 2.2e-10 39.9 3.5 0.16 10.8 0.0 5.2 2 2 3 5 5 5 4 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 KIK53577.1 - 3.9e-09 36.4 22.2 1.5e-05 24.7 5.8 4.2 1 1 1 3 3 3 3 PQQ-like domain Ge1_WD40 PF16529.5 KIK53577.1 - 6.8e-09 35.1 19.9 0.042 12.8 0.0 10.2 1 1 11 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK53577.1 - 1e-08 35.3 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 KIK53577.1 - 2.3e-06 26.4 10.7 0.061 11.9 0.0 4.9 4 1 2 6 6 6 3 Cytochrome D1 heme domain NB-ARC PF00931.22 KIK53577.1 - 1e-05 24.9 0.0 3.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain PQQ PF01011.21 KIK53577.1 - 4.2e-05 23.3 3.0 46 4.2 0.0 8.4 9 0 0 9 9 9 0 PQQ enzyme repeat AAA_16 PF13191.6 KIK53577.1 - 8.8e-05 22.9 0.0 0.00029 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK53577.1 - 0.0009 19.7 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KIK53577.1 - 0.0012 18.8 12.7 34 4.5 0.0 9.1 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.27 KIK53577.1 - 0.0015 19.1 0.0 0.0065 17.0 0.0 2.1 2 0 0 2 2 1 1 ABC transporter Torsin PF06309.11 KIK53577.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.22 KIK53577.1 - 0.021 15.2 2.4 0.23 11.9 0.0 3.9 4 1 1 5 5 3 0 RNA helicase VID27 PF08553.10 KIK53577.1 - 0.043 12.9 0.2 1.5 7.8 0.0 2.5 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain NAGPA PF09992.9 KIK53577.1 - 0.072 13.3 3.5 11 6.2 0.1 4.5 2 2 4 6 6 6 0 Phosphodiester glycosidase AAA_18 PF13238.6 KIK53577.1 - 0.084 13.4 0.0 0.3 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 KIK53577.1 - 0.13 12.4 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain APS_kinase PF01583.20 KIK53577.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PQQ_3 PF13570.6 KIK53577.1 - 0.21 12.1 16.0 24 5.6 0.1 8.0 10 0 0 10 10 9 0 PQQ-like domain WD40 PF00400.32 KIK53578.1 - 2.6e-110 357.2 63.9 9.3e-09 35.8 0.0 14.3 14 0 0 14 14 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53578.1 - 3.2e-28 97.8 20.2 0.044 14.1 0.1 12.2 1 1 12 13 13 13 9 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53578.1 - 6.5e-17 61.1 1.3 0.019 13.3 0.0 8.5 3 2 6 10 10 10 7 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK53578.1 - 1.2e-14 54.1 16.2 0.043 12.8 0.0 9.6 1 1 8 10 10 10 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK53578.1 - 7.8e-11 41.8 6.2 0.013 14.9 0.1 7.2 3 2 7 10 10 10 2 WD40-like domain PQQ_2 PF13360.6 KIK53578.1 - 1.1e-10 41.5 26.3 9.1e-07 28.7 8.9 4.7 2 1 0 3 3 3 3 PQQ-like domain eIF2A PF08662.11 KIK53578.1 - 1.7e-10 41.1 3.6 0.16 11.8 0.0 5.4 2 2 5 7 7 7 5 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK53578.1 - 1.4e-08 33.7 14.9 0.0026 16.3 0.5 5.3 2 2 3 6 6 6 5 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 KIK53578.1 - 9.6e-08 31.3 2.3 1.3 7.8 0.0 5.6 3 1 3 6 6 6 3 Methylamine dehydrogenase heavy chain (MADH) NACHT PF05729.12 KIK53578.1 - 1e-06 28.8 0.0 4e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK53578.1 - 0.00038 20.9 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK53578.1 - 0.001 18.3 0.0 0.013 14.7 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK53578.1 - 0.0059 17.0 0.8 0.17 12.3 0.0 3.7 3 1 1 4 4 4 1 RNA helicase AAA_19 PF13245.6 KIK53578.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK53578.1 - 0.015 15.8 0.0 0.061 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain PQQ PF01011.21 KIK53578.1 - 0.023 14.6 6.5 78 3.5 0.0 7.5 11 0 0 11 11 9 0 PQQ enzyme repeat VID27 PF08553.10 KIK53578.1 - 0.028 13.5 1.2 0.15 11.1 0.1 2.4 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain AAA PF00004.29 KIK53578.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1258 PF06869.12 KIK53578.1 - 0.038 13.5 2.2 18 4.7 0.0 4.4 3 2 4 7 7 7 0 Protein of unknown function (DUF1258) ABC_tran PF00005.27 KIK53578.1 - 0.049 14.2 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter PQQ_3 PF13570.6 KIK53578.1 - 0.054 14.0 20.5 2.6 8.6 0.1 8.7 9 0 0 9 9 8 0 PQQ-like domain Roc PF08477.13 KIK53578.1 - 0.12 12.6 7.1 3.3 8.0 0.0 5.7 4 3 2 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIK53578.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK53578.1 - 0.13 11.9 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF374 PF04028.13 KIK53578.1 - 0.14 11.7 0.1 5.8 6.6 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF374) DUF5114 PF17141.4 KIK53578.1 - 3.4 8.2 4.7 11 6.6 0.0 4.1 5 2 1 6 6 3 0 Domain of unknown function (DUF5114) DUF4047 PF13256.6 KIK53579.1 - 0.088 13.0 0.6 0.22 11.7 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) COG2 PF06148.11 KIK53579.1 - 0.1 12.7 1.6 0.23 11.6 1.6 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0228 PF05727.11 KIK53579.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) DUF4796 PF16044.5 KIK53581.1 - 0.032 13.8 0.1 0.67 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) CagD PF16567.5 KIK53582.1 - 0.19 11.5 0.1 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Pathogenicity island component CagD Syntaxin-6_N PF09177.11 KIK53583.1 - 0.16 12.5 0.0 0.46 11.1 0.0 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PT PF04886.12 KIK53583.1 - 5.3 6.7 10.7 0.82 9.3 1.7 2.8 2 1 0 2 2 2 0 PT repeat CxC4 PF18717.1 KIK53586.1 - 2e-42 144.1 0.1 4e-42 143.1 0.0 1.5 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases zf-TFIIB PF13453.6 KIK53586.1 - 0.057 12.8 4.2 1.1 8.6 2.2 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger KDZ PF18758.1 KIK53587.1 - 0.00054 19.6 1.6 0.00063 19.4 1.6 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase WD40 PF00400.32 KIK53589.1 - 2.6e-105 341.3 59.7 2.2e-09 37.7 0.0 13.0 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53589.1 - 9.2e-29 99.6 18.5 0.049 13.9 0.1 11.7 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53589.1 - 1.4e-18 66.5 0.8 0.28 9.4 0.1 9.6 2 2 8 10 10 10 7 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53589.1 - 5.8e-14 52.1 2.2 0.028 13.7 0.0 6.7 5 2 2 7 7 7 3 WD40-like domain Me-amine-dh_H PF06433.11 KIK53589.1 - 9.8e-12 44.4 1.1 0.044 12.7 0.0 5.0 2 2 4 6 6 6 5 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 KIK53589.1 - 2.2e-11 43.3 20.4 0.01 14.9 0.0 9.7 1 1 9 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK53589.1 - 1e-10 41.6 20.6 2.6e-06 27.2 9.1 5.0 1 1 1 3 3 3 2 PQQ-like domain PD40 PF07676.12 KIK53589.1 - 7.4e-10 38.5 7.4 22 5.2 0.0 9.9 11 0 0 11 11 10 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.12 KIK53589.1 - 6.8e-06 25.7 0.3 2.6 7.5 0.0 4.8 3 2 1 5 5 5 2 Protein of unknown function (DUF1258) PQQ PF01011.21 KIK53589.1 - 2.7e-05 23.9 0.5 26 5.0 0.0 7.3 8 0 0 8 8 8 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK53589.1 - 3.1e-05 22.7 12.1 0.4 9.2 0.1 4.8 2 1 1 4 4 4 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KIK53589.1 - 0.00043 19.5 3.9 0.11 11.6 0.1 3.5 1 1 3 4 4 4 2 Coatomer WD associated region Big_7 PF17957.1 KIK53589.1 - 0.0031 18.2 29.0 8.4 7.2 0.4 8.6 4 4 6 10 10 10 0 Bacterial Ig domain VID27 PF08553.10 KIK53589.1 - 0.022 13.8 0.4 1.9 7.5 0.1 2.6 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF2019 PF09450.10 KIK53589.1 - 0.04 13.9 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) DUF1652 PF07865.11 KIK53589.1 - 0.065 13.1 0.1 47 3.9 0.0 4.7 5 0 0 5 5 4 0 Protein of unknown function (DUF1652) SLH PF00395.20 KIK53589.1 - 0.069 13.2 0.0 1e+02 3.0 0.0 4.9 6 0 0 6 6 6 0 S-layer homology domain PT-TG PF14449.6 KIK53589.1 - 0.16 11.9 1.3 1.2e+02 2.6 0.0 4.6 6 0 0 6 6 5 0 Pre-toxin TG DUF374 PF04028.13 KIK53589.1 - 0.56 9.8 5.1 9.8 5.8 0.0 5.1 6 1 0 6 6 5 0 Domain of unknown function (DUF374) PSCyt1 PF07635.11 KIK53589.1 - 1.2 9.8 9.7 2.9e+02 2.2 0.0 7.1 10 1 0 10 10 7 0 Planctomycete cytochrome C Nup160 PF11715.8 KIK53589.1 - 1.3 7.6 7.8 12 4.4 0.0 4.9 3 2 3 6 6 6 0 Nucleoporin Nup120/160 DUF5114 PF17141.4 KIK53589.1 - 6.1 7.4 8.7 14 6.3 0.2 4.9 1 1 6 7 7 7 0 Domain of unknown function (DUF5114) WD40 PF00400.32 KIK53590.1 - 1.7e-35 120.4 25.6 1.4e-06 28.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53590.1 - 3.1e-09 37.0 1.6 0.15 12.4 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53590.1 - 2.2e-05 23.9 0.0 0.74 9.1 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain Frtz PF11768.8 KIK53590.1 - 0.0001 20.8 0.2 4.3 5.5 0.0 4.2 2 2 2 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK53590.1 - 0.0004 20.1 1.5 0.0097 15.5 1.3 2.4 1 1 1 2 2 2 2 PQQ-like domain PALB2_WD40 PF16756.5 KIK53590.1 - 0.0062 15.5 2.1 5.2 5.9 0.1 3.7 1 1 3 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KIK53590.1 - 0.01 14.4 0.5 0.93 8.0 0.1 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain PQQ PF01011.21 KIK53590.1 - 0.014 15.3 0.0 72 3.6 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat DUF2019 PF09450.10 KIK53590.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) WD40 PF00400.32 KIK53591.1 - 8.1e-45 149.9 13.7 1.9e-10 41.2 1.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53591.1 - 2.9e-12 46.7 2.7 0.0027 18.0 0.1 4.7 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK53591.1 - 4.5e-06 26.7 0.5 0.00077 19.4 0.1 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK53591.1 - 2.8e-05 23.6 0.3 0.25 10.6 0.0 3.4 1 1 1 3 3 3 2 WD40-like domain Frtz PF11768.8 KIK53591.1 - 0.00013 20.4 0.0 0.94 7.7 0.0 3.1 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK53591.1 - 0.0019 17.1 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 KIK53591.1 - 0.0057 16.3 4.5 4.1 6.9 0.1 2.9 1 1 1 3 3 3 3 PQQ-like domain PD40 PF07676.12 KIK53591.1 - 0.04 13.9 0.1 12 6.0 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF5570 PF17731.1 KIK53591.1 - 0.043 13.9 4.0 0.13 12.4 0.2 2.9 1 1 3 4 4 4 0 Family of unknown function (DUF5570) Ge1_WD40 PF16529.5 KIK53591.1 - 0.052 12.5 1.2 11 4.8 0.0 3.4 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIK53591.1 - 0.16 10.8 3.8 2.6 6.9 0.3 3.4 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DNA_pol_A_exo1 PF01612.20 KIK53592.1 - 2e-14 53.7 0.0 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease GAGE PF05831.11 KIK53593.1 - 0.074 13.6 0.4 0.13 12.8 0.4 1.4 1 0 0 1 1 1 0 GAGE protein DNA_pol_A_exo1 PF01612.20 KIK53594.1 - 0.14 11.9 0.4 21 4.8 0.0 2.5 1 1 1 2 2 2 0 3'-5' exonuclease PhoU_div PF01865.16 KIK53595.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 Wx5_PLAF3D7 PF09688.10 KIK53595.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) WD40 PF00400.32 KIK53596.1 - 4.7e-107 346.9 51.8 9.3e-10 39.0 0.1 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53596.1 - 1e-27 96.2 15.0 0.18 12.1 0.0 12.0 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53596.1 - 1.6e-12 47.4 4.4 0.12 11.6 0.0 7.1 3 3 3 7 7 7 5 WD40-like domain Frtz PF11768.8 KIK53596.1 - 3.1e-11 42.3 1.4 1.6 7.0 0.0 8.2 3 3 5 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK53596.1 - 5.1e-10 38.8 18.5 0.58 9.1 2.1 9.6 1 1 7 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KIK53596.1 - 4.7e-09 35.6 0.9 0.45 9.3 0.0 4.8 3 2 1 4 4 4 4 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 KIK53596.1 - 1.4e-08 34.6 17.6 0.0011 18.7 6.7 4.8 1 1 2 3 3 3 3 PQQ-like domain NACHT PF05729.12 KIK53596.1 - 6.1e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PQQ PF01011.21 KIK53596.1 - 3.6e-07 29.8 0.3 37 4.5 0.0 8.2 10 0 0 10 10 9 0 PQQ enzyme repeat NB-ARC PF00931.22 KIK53596.1 - 0.00048 19.4 0.0 0.004 16.4 0.0 2.3 2 1 0 2 2 2 1 NB-ARC domain PD40 PF07676.12 KIK53596.1 - 0.0019 18.1 9.6 43 4.2 0.0 7.9 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.27 KIK53596.1 - 0.0086 16.6 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK53596.1 - 0.0087 16.5 0.0 0.044 14.2 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KIK53596.1 - 0.0098 14.5 10.9 1.1 7.7 0.1 4.6 2 2 3 5 5 5 2 Cytochrome D1 heme domain AAA PF00004.29 KIK53596.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK53596.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NAGPA PF09992.9 KIK53596.1 - 0.32 11.2 4.1 24 5.1 0.0 4.6 4 2 2 6 6 5 0 Phosphodiester glycosidase DUF5114 PF17141.4 KIK53596.1 - 0.87 10.2 3.1 51 4.5 0.0 4.6 3 1 1 5 5 5 0 Domain of unknown function (DUF5114) Alpha_kinase PF02816.18 KIK53599.1 - 4.3e-08 33.5 0.0 5.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Tubulin_3 PF14881.6 KIK53600.1 - 0.0027 17.4 0.0 0.0027 17.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin domain DUF4283 PF14111.6 KIK53601.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) WD40 PF00400.32 KIK53603.1 - 3e-117 379.1 73.0 2.2e-09 37.8 1.1 15.1 16 0 0 16 16 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53603.1 - 3.3e-26 91.4 22.0 0.0041 17.4 0.1 12.7 1 1 12 13 13 13 7 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK53603.1 - 7.2e-16 57.6 5.3 0.21 9.8 0.0 10.7 3 2 7 12 12 12 5 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53603.1 - 1.3e-14 54.3 6.2 0.081 12.2 0.0 8.0 4 3 2 8 8 8 3 WD40-like domain PQQ_2 PF13360.6 KIK53603.1 - 9.8e-11 41.7 25.4 2.2e-05 24.2 7.2 5.5 1 1 3 4 4 4 4 PQQ-like domain NACHT PF05729.12 KIK53603.1 - 6e-10 39.3 0.2 1.4e-09 38.1 0.0 1.8 2 0 0 2 2 1 1 NACHT domain Ge1_WD40 PF16529.5 KIK53603.1 - 1.1e-09 37.7 19.2 0.0024 16.9 0.0 9.5 1 1 7 10 10 10 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK53603.1 - 3.4e-08 32.4 14.5 0.0002 20.0 1.0 5.2 2 1 1 5 5 5 3 Cytochrome D1 heme domain AAA_16 PF13191.6 KIK53603.1 - 4.7e-07 30.4 0.0 3.1e-06 27.7 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain PD40 PF07676.12 KIK53603.1 - 1.2e-05 25.1 8.8 1e+02 3.0 0.0 9.9 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat NB-ARC PF00931.22 KIK53603.1 - 2e-05 23.9 0.1 7.6e-05 22.0 0.0 1.9 2 1 0 2 2 2 1 NB-ARC domain PQQ PF01011.21 KIK53603.1 - 0.00037 20.3 1.8 73 3.6 0.0 8.5 12 0 0 12 12 12 0 PQQ enzyme repeat AAA PF00004.29 KIK53603.1 - 0.00075 19.9 0.0 0.0023 18.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK53603.1 - 0.0026 18.1 0.5 0.14 12.5 0.1 4.1 2 1 3 5 5 5 1 RNA helicase DUF1258 PF06869.12 KIK53603.1 - 0.0055 16.2 4.6 14 5.1 0.1 4.6 5 1 1 6 6 5 0 Protein of unknown function (DUF1258) Torsin PF06309.11 KIK53603.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 KIK53603.1 - 0.019 15.5 0.0 0.063 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KIK53603.1 - 0.022 15.1 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain VID27 PF08553.10 KIK53603.1 - 0.036 13.1 1.7 2.4 7.1 0.1 3.4 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain AAA_30 PF13604.6 KIK53603.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK53603.1 - 0.069 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PDE6_gamma PF04868.12 KIK53603.1 - 0.097 12.9 0.0 56 4.1 0.0 4.5 5 0 0 5 5 4 0 Retinal cGMP phosphodiesterase, gamma subunit APS_kinase PF01583.20 KIK53603.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.17 KIK53603.1 - 0.15 12.2 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF2019 PF09450.10 KIK53603.1 - 0.16 12.0 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Retrotrans_gag PF03732.17 KIK53604.1 - 4.5e-05 23.6 0.2 0.00071 19.8 0.2 2.4 1 1 0 1 1 1 1 Retrotransposon gag protein DUF668 PF05003.12 KIK53604.1 - 0.17 12.4 0.0 0.5 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF668) zf-CCHC PF00098.23 KIK53604.1 - 0.33 11.1 9.6 0.44 10.7 1.1 2.6 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 KIK53605.1 - 9e-22 77.0 7.3 4.2e-10 40.1 2.4 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53605.1 - 0.00013 22.1 0.3 0.27 11.5 0.2 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53605.1 - 0.0026 16.8 0.1 0.74 8.7 0.0 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK53605.1 - 0.0031 15.9 0.0 1.1 7.5 0.0 2.0 1 1 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK53605.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 WD40-like domain PQQ_2 PF13360.6 KIK53605.1 - 0.024 14.2 0.9 0.066 12.8 0.9 1.7 1 1 0 1 1 1 0 PQQ-like domain SH3_16 PF18348.1 KIK53605.1 - 0.13 12.1 0.1 1 9.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain PIF1 PF05970.14 KIK53606.1 - 2.1e-06 27.2 0.5 0.046 12.9 0.6 3.0 2 1 0 2 2 2 2 PIF1-like helicase Eaf7 PF07904.13 KIK53606.1 - 0.088 13.2 0.2 0.22 11.9 0.2 1.8 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 PIF1 PF05970.14 KIK53607.1 - 1.2e-05 24.7 0.1 1.8e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KIK53607.1 - 0.0023 18.3 0.2 0.0064 16.9 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain DUF719 PF05334.13 KIK53607.1 - 0.028 14.6 0.9 0.097 12.9 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF719) TBCC_N PF16752.5 KIK53607.1 - 0.039 14.4 1.3 0.052 14.0 1.3 1.1 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain AAA_30 PF13604.6 KIK53607.1 - 0.048 13.4 0.1 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK53607.1 - 0.064 13.6 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RTX PF02382.15 KIK53607.1 - 0.081 12.6 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein VPS13_mid_rpt PF16910.5 KIK53607.1 - 0.11 11.9 1.2 0.25 10.7 0.5 1.7 2 0 0 2 2 2 0 Repeating coiled region of VPS13 NB-ARC PF00931.22 KIK53607.1 - 0.42 9.8 2.9 0.15 11.2 0.4 1.6 2 1 0 2 2 2 0 NB-ARC domain Helitron_like_N PF14214.6 KIK53608.1 - 8.3e-19 68.5 0.0 1e-18 68.2 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Pro_isomerase PF00160.21 KIK53611.1 - 6.7e-41 140.2 0.1 7.7e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phage_spike PF18715.1 KIK53613.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Phage spike trimer p450 PF00067.22 KIK53616.1 - 5.1e-59 200.2 0.0 6.7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 KIK53616.1 - 0.012 15.8 0.1 0.061 13.5 0.0 2.0 2 0 0 2 2 2 0 Stirrup Methyltransf_23 PF13489.6 KIK53617.1 - 4.4e-11 42.9 0.0 8.2e-11 42.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK53617.1 - 1e-10 42.2 0.0 2.8e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK53617.1 - 6.1e-08 32.6 0.0 3.1e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK53617.1 - 1.2e-07 32.3 0.0 2.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK53617.1 - 2.8e-06 26.9 0.0 6.8e-05 22.3 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIK53617.1 - 0.0017 19.1 0.0 0.0074 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PelG PF16933.5 KIK53618.1 - 0.0021 17.0 6.4 0.0024 16.8 6.4 1.0 1 0 0 1 1 1 1 Putative exopolysaccharide Exporter (EPS-E) Exonuc_VIII PF06630.11 KIK53619.1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII DUF2717 PF10911.8 KIK53621.1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Collagen PF01391.18 KIK53623.1 - 2.9e-05 23.7 41.7 0.00063 19.5 41.7 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Fasciclin PF02469.22 KIK53623.1 - 0.15 12.2 0.2 0.24 11.6 0.2 1.2 1 0 0 1 1 1 0 Fasciclin domain zf-CCHC PF00098.23 KIK53624.1 - 0.00023 21.1 4.4 0.00023 21.1 4.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIK53624.1 - 0.15 11.9 2.2 0.29 11.0 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 KIK53625.1 - 2.5e-06 27.7 0.0 4.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK53625.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Glyco_hydro_75 PF07335.11 KIK53630.1 - 3.2e-23 82.8 0.1 4.9e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SR-25 PF10500.9 KIK53630.1 - 9 5.8 12.7 13 5.3 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.23 KIK53631.1 - 0.00014 21.8 3.8 0.00014 21.8 3.8 1.9 2 0 0 2 2 2 1 Zinc knuckle IBR PF01485.21 KIK53631.1 - 0.039 14.2 0.5 0.071 13.4 0.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Retrotrans_gag PF03732.17 KIK53631.1 - 0.061 13.6 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein DUF648 PF04890.13 KIK53632.1 - 0.17 11.6 0.3 0.23 11.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) PKcGMP_CC PF16808.5 KIK53632.1 - 0.21 11.5 3.0 4.8 7.1 0.3 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK53633.1 - 0.011 15.8 0.4 0.021 14.9 0.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK53633.1 - 0.054 13.9 10.7 0.055 13.9 8.9 1.7 1 1 1 2 2 2 0 Fez1 HMMR_N PF15905.5 KIK53633.1 - 0.056 12.9 8.2 0.091 12.2 8.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK53633.1 - 0.058 12.3 11.3 0.089 11.7 11.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KIK53633.1 - 0.14 12.0 9.2 1.7 8.6 0.7 3.7 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bacillus_HBL PF05791.11 KIK53633.1 - 0.19 11.5 1.1 0.49 10.2 1.3 1.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PEP-utilisers_N PF05524.13 KIK53633.1 - 0.36 11.0 4.9 4.5 7.5 5.1 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Sec2p PF06428.11 KIK53633.1 - 0.38 10.7 12.1 0.036 14.0 1.9 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 KIK53633.1 - 0.5 10.5 11.9 0.093 12.8 6.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KIK53633.1 - 0.91 9.9 8.6 0.57 10.5 2.7 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KIK53633.1 - 1 10.0 5.1 3.7 8.2 0.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KIK53633.1 - 1.1 8.6 7.7 1.6 8.0 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 KIK53633.1 - 1.2 9.2 14.0 5.3 7.1 1.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 KIK53633.1 - 2 8.2 7.5 2.2 8.1 1.3 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Csm1_N PF18504.1 KIK53633.1 - 2.4 8.5 11.7 0.8 10.1 2.7 3.0 1 1 3 4 4 4 0 Csm1 N-terminal domain KASH_CCD PF14662.6 KIK53633.1 - 2.5 7.9 14.6 3.3 7.5 1.6 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Phytochelatin PF05023.14 KIK53635.1 - 0.017 14.3 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Phytochelatin synthase TSNAXIP1_N PF15739.5 KIK53642.1 - 0.007 16.7 1.5 0.013 15.8 1.5 1.5 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus DUF648 PF04890.13 KIK53642.1 - 0.014 15.2 0.3 0.02 14.7 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Golgin_A5 PF09787.9 KIK53642.1 - 0.023 14.2 4.4 0.04 13.4 4.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TED_complement PF07678.14 KIK53642.1 - 0.023 13.7 0.2 0.034 13.2 0.2 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF327 PF03885.13 KIK53642.1 - 0.03 14.3 0.6 0.049 13.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) UPF0242 PF06785.11 KIK53642.1 - 0.24 11.5 5.7 0.43 10.7 5.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 KIK53642.1 - 0.45 10.2 4.6 1.9 8.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 KIK53642.1 - 1.9 8.7 4.4 4.3 7.5 0.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CxC1 PF18802.1 KIK53644.1 - 4.9e-09 36.3 0.1 6.6e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIK53644.1 - 2e-06 27.9 0.1 2.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK53645.1 - 3.5e-26 92.2 4.5 4.4e-26 91.9 4.5 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Nucleoporin_FG2 PF15967.5 KIK53648.1 - 0.39 9.2 3.4 0.46 9.0 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Arm PF00514.23 KIK53651.1 - 2.9e-65 214.5 15.6 6.2e-12 45.1 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KIK53651.1 - 3e-16 58.7 0.1 6.7e-16 57.6 0.1 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KIK53651.1 - 3.8e-15 56.0 2.3 0.00037 20.9 0.0 6.0 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KIK53651.1 - 3.9e-12 46.4 0.0 0.0037 17.6 0.0 5.3 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.22 KIK53651.1 - 6.1e-08 32.3 1.4 2.8 8.4 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 KIK53651.1 - 4e-05 22.4 0.1 0.0037 15.9 0.0 3.2 2 1 0 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 KIK53651.1 - 0.00011 22.4 3.8 0.0052 17.0 0.0 4.3 5 1 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Katanin_con80 PF13925.6 KIK53651.1 - 0.06 13.4 0.0 0.3 11.1 0.0 2.1 1 1 0 1 1 1 0 con80 domain of Katanin FKBP_N_2 PF18023.1 KIK53653.1 - 0.041 14.0 0.4 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 BDBT FKBP like N-terminal DUF3243 PF11588.8 KIK53653.1 - 0.081 13.2 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) SIKE PF05769.11 KIK53653.1 - 0.25 11.3 11.5 1.6 8.7 3.9 3.4 2 1 1 3 3 3 0 SIKE family DUF4600 PF15372.6 KIK53653.1 - 1.3 9.4 5.6 1.1 9.7 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4600) ZapB PF06005.12 KIK53653.1 - 1.8 9.1 16.4 6.6 7.3 1.5 4.1 2 2 1 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 KIK53653.1 - 2.6 8.4 10.2 8.1 6.8 0.1 3.9 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KIK53653.1 - 6.5 6.9 9.7 2.4 8.3 0.1 3.7 4 1 0 4 4 4 0 bZIP transcription factor F-box PF00646.33 KIK53654.1 - 1.8e-06 27.7 0.2 2.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK53654.1 - 0.00078 19.3 0.5 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK53654.1 - 0.11 12.9 0.1 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Mucin PF01456.17 KIK53655.1 - 0.92 9.5 3.2 2 8.4 1.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RXT2_N PF08595.11 KIK53657.1 - 0.21 11.6 9.6 0.29 11.2 3.3 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Presenilin PF01080.17 KIK53657.1 - 0.26 10.0 2.0 0.28 9.9 2.0 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 KIK53657.1 - 0.64 9.3 15.2 0.078 12.3 7.4 2.3 2 0 0 2 2 2 0 NOA36 protein Pox_Ag35 PF03286.14 KIK53657.1 - 6.1 6.6 13.7 0.33 10.7 6.3 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Spc7 PF08317.11 KIK53658.1 - 0.016 14.1 9.4 0.025 13.5 9.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LRS4 PF10422.9 KIK53658.1 - 0.12 11.9 4.1 0.23 11.0 4.1 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fez1 PF06818.15 KIK53658.1 - 0.28 11.6 9.3 0.13 12.8 4.6 2.0 1 1 1 2 2 2 0 Fez1 HALZ PF02183.18 KIK53658.1 - 0.46 10.8 5.6 0.36 11.1 2.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper PEP-utilisers_N PF05524.13 KIK53658.1 - 0.62 10.2 4.2 1.4 9.2 4.2 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Csm1_N PF18504.1 KIK53658.1 - 1.4 9.3 10.0 1.9 8.9 1.0 3.1 1 1 3 4 4 4 0 Csm1 N-terminal domain KASH_CCD PF14662.6 KIK53658.1 - 1.6 8.6 12.6 1.7 8.5 10.0 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF641 PF04859.12 KIK53658.1 - 2.3 8.6 6.2 4.3 7.7 4.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 KIK53658.1 - 2.3 8.6 8.0 2.2 8.7 0.6 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Sec2p PF06428.11 KIK53658.1 - 2.4 8.2 7.9 0.7 9.9 1.0 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ZapB PF06005.12 KIK53658.1 - 2.5 8.6 13.5 7.3 7.1 0.9 2.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF4200 PF13863.6 KIK53658.1 - 3.8 7.9 12.5 1.7 9.0 5.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) YabA PF06156.13 KIK53658.1 - 4.5 8.0 6.5 3.9 8.2 0.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA PKcGMP_CC PF16808.5 KIK53658.1 - 6.3 6.7 12.7 8.9 6.3 0.5 3.9 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 KIK53658.1 - 7.9 6.5 9.2 10 6.2 0.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF648 PF04890.13 KIK53659.1 - 0.024 14.4 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) HR1 PF02185.16 KIK53659.1 - 2.2 8.5 7.9 0.45 10.7 1.8 2.4 2 1 0 2 2 2 0 Hr1 repeat FoP_duplication PF13865.6 KIK53660.1 - 4.3 7.9 12.4 0.7 10.5 2.2 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SSP160 PF06933.11 KIK53666.1 - 0.25 9.5 12.4 0.31 9.2 12.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_C12 PF01088.21 KIK53669.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3612 PF12268.8 KIK53669.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Arm PF00514.23 KIK53671.1 - 3.3e-78 255.6 9.9 3.9e-11 42.6 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK53671.1 - 1.6e-22 79.6 0.9 4.6e-08 33.4 0.0 5.6 4 1 1 5 5 5 4 HEAT-like repeat Arm_3 PF16186.5 KIK53671.1 - 3.6e-17 61.6 0.1 7.8e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KIK53671.1 - 2.5e-16 59.8 0.0 0.0004 20.7 0.0 5.2 1 1 4 5 5 5 4 HEAT repeats IBB PF01749.20 KIK53671.1 - 4e-14 52.8 0.1 8.9e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 KIK53671.1 - 1.8e-13 49.5 2.0 0.00032 20.7 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 KIK53671.1 - 0.00024 19.8 0.0 0.014 14.0 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 KIK53671.1 - 0.0017 18.6 2.3 0.18 12.0 0.0 3.8 4 2 2 6 6 5 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KIK53671.1 - 0.0047 17.0 0.0 13 6.0 0.0 4.2 4 2 1 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.16 KIK53671.1 - 0.012 16.2 1.9 7.9 7.5 0.0 4.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat CTNNBL PF08216.11 KIK53671.1 - 0.028 14.6 0.1 13 6.0 0.0 4.2 4 1 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear NopRA1 PF16201.5 KIK53671.1 - 0.03 13.9 0.1 7.6 6.1 0.0 3.8 2 1 3 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 DUF3361 PF11841.8 KIK53671.1 - 0.062 13.2 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) NPL PF17800.1 KIK53672.1 - 0.00057 20.4 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Nucleoplasmin-like domain Band_3_cyto PF07565.13 KIK53672.1 - 0.074 12.8 0.3 0.19 11.5 0.0 1.8 1 1 1 2 2 2 0 Band 3 cytoplasmic domain TPR_10 PF13374.6 KIK53675.1 - 9.3e-69 225.6 7.4 8.7e-09 35.0 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53675.1 - 4.9e-62 206.2 26.3 4.1e-10 39.8 0.0 8.6 2 1 8 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53675.1 - 2.3e-09 36.6 16.1 1.5 9.0 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK53675.1 - 1e-08 35.2 0.1 0.059 13.6 0.0 5.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIK53675.1 - 1.7e-08 34.0 6.1 4.3 7.8 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53675.1 - 3.6e-08 33.8 2.8 0.87 10.1 0.0 6.2 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53675.1 - 1.6e-07 30.8 19.9 0.43 10.5 0.1 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK53675.1 - 5.5e-07 29.6 0.1 0.76 9.9 0.0 6.2 6 2 1 7 7 5 1 Rapsyn N-terminal myristoylation and linker region TPR_MalT PF17874.1 KIK53675.1 - 2.9e-06 26.9 2.2 0.00035 20.1 0.1 2.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KIK53675.1 - 1.9e-05 24.4 22.0 1.5 9.1 0.1 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK53675.1 - 2.1e-05 24.7 2.4 3.7 8.4 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat MCPVI PF02993.14 KIK53675.1 - 3.8e-05 23.6 2.3 5.5 6.8 0.0 5.2 1 1 5 6 6 6 1 Minor capsid protein VI PPR PF01535.20 KIK53675.1 - 8e-05 22.6 0.6 84 3.8 0.0 6.5 7 0 0 7 7 6 0 PPR repeat TPR_14 PF13428.6 KIK53675.1 - 0.00042 20.9 0.7 7.4 7.7 0.0 6.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK53675.1 - 0.00045 20.3 2.3 26 5.1 0.0 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK53675.1 - 0.00086 19.6 1.8 65 4.0 0.0 6.5 3 2 4 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIK53675.1 - 0.0066 16.5 6.7 24 5.0 0.0 5.8 3 1 4 8 8 7 0 Domain of Unknown Function (DUF3856) YqaH PF17448.2 KIK53675.1 - 0.0085 16.4 0.2 11 6.4 0.0 4.3 3 1 0 4 4 3 0 Uncharacterized YqaH-like TPR_6 PF13174.6 KIK53675.1 - 0.0099 16.5 1.6 2.1e+02 2.9 0.0 6.5 6 0 0 6 6 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KIK53675.1 - 0.026 14.8 2.8 1.1 9.5 0.0 4.3 4 2 1 6 6 4 0 Vacuolar sorting protein 39 domain 1 TrwB_AAD_bind PF10412.9 KIK53675.1 - 0.037 12.9 0.0 0.078 11.9 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain BTAD PF03704.17 KIK53675.1 - 0.04 14.3 4.2 12 6.3 0.1 4.6 3 1 1 4 4 4 0 Bacterial transcriptional activator domain AAA_16 PF13191.6 KIK53675.1 - 0.045 14.1 0.0 0.16 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Titin_Ig-rpts PF06582.12 KIK53675.1 - 0.083 12.8 0.5 72 3.4 0.1 4.7 6 0 0 6 6 4 0 Titin repeat AAA_22 PF13401.6 KIK53675.1 - 0.099 12.9 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain TPR_17 PF13431.6 KIK53675.1 - 0.28 11.7 12.0 20 5.8 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat RIG-I_C PF18119.1 KIK53675.1 - 0.79 9.7 2.8 3.9 7.5 0.0 3.3 3 1 1 4 4 4 0 RIG-I receptor C-terminal domain Aldedh PF00171.22 KIK53677.1 - 1.1e-42 146.1 0.0 1.5e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_10 PF13374.6 KIK53678.1 - 2.3e-64 211.7 4.0 7.8e-07 28.8 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53678.1 - 2.3e-51 172.0 12.3 9.3e-12 45.1 0.2 7.3 1 1 5 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53678.1 - 2.7e-10 40.6 0.4 0.4 11.2 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53678.1 - 5.7e-10 38.6 18.2 0.043 13.6 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53678.1 - 1.3e-09 37.4 18.1 0.29 11.3 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53678.1 - 3.9e-09 35.9 25.6 0.21 11.8 0.1 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK53678.1 - 4.5e-09 36.4 0.9 0.0061 16.8 0.0 5.5 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIK53678.1 - 3.7e-07 29.8 10.8 1 9.8 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK53678.1 - 8e-07 29.1 0.2 0.87 9.7 0.0 6.8 3 2 4 7 7 7 1 Rapsyn N-terminal myristoylation and linker region TPR_9 PF13371.6 KIK53678.1 - 2.7e-05 24.2 2.8 1.8 8.8 0.0 4.9 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK53678.1 - 0.00015 22.3 0.5 10 6.8 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK53678.1 - 0.00018 21.8 0.0 14 6.6 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KIK53678.1 - 0.00021 21.3 0.2 14 6.2 0.0 5.6 6 0 0 6 6 5 0 PPR repeat SRP_TPR_like PF17004.5 KIK53678.1 - 0.00081 19.4 0.5 10 6.2 0.0 4.8 4 1 0 5 5 3 0 Putative TPR-like repeat TPR_14 PF13428.6 KIK53678.1 - 0.00098 19.8 1.8 28 5.9 0.0 5.5 7 0 0 7 7 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK53678.1 - 0.0011 18.5 10.6 10 5.4 0.1 4.4 2 1 2 4 4 4 0 MalT-like TPR region TPR_11 PF13414.6 KIK53678.1 - 0.012 15.3 3.5 5.2 6.8 0.0 4.8 5 0 0 5 5 5 0 TPR repeat MCPVI PF02993.14 KIK53678.1 - 0.023 14.5 2.3 35 4.1 0.0 4.6 1 1 4 6 6 6 0 Minor capsid protein VI YqaH PF17448.2 KIK53678.1 - 0.025 14.9 0.1 52 4.2 0.0 4.5 4 0 0 4 4 4 0 Uncharacterized YqaH-like DUF2664 PF10867.8 KIK53678.1 - 0.035 14.5 4.4 18 5.8 0.0 5.3 7 0 0 7 7 5 0 Protein of unknown function (DUF2664) TPR_6 PF13174.6 KIK53678.1 - 0.042 14.5 2.9 2.7e+02 2.6 0.0 6.3 7 1 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK53678.1 - 0.062 13.0 0.2 8.3 6.1 0.0 3.9 3 1 1 4 4 4 0 26S proteasome subunit RPN7 RIG-I_C PF18119.1 KIK53678.1 - 0.091 12.8 2.1 14 5.7 0.0 4.0 2 1 2 4 4 4 0 RIG-I receptor C-terminal domain Zincin_2 PF10103.9 KIK53678.1 - 0.13 11.5 0.1 6.6 5.9 0.0 2.7 2 1 0 2 2 2 0 Zincin-like metallopeptidase Titin_Ig-rpts PF06582.12 KIK53678.1 - 0.18 11.8 1.6 20 5.2 0.0 3.9 3 0 0 3 3 3 0 Titin repeat TPR_17 PF13431.6 KIK53678.1 - 8.7 7.0 14.6 48 4.7 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Aldedh PF00171.22 KIK53679.1 - 2.2e-09 36.4 0.0 2.7e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_10 PF13374.6 KIK53681.1 - 1.1e-77 254.0 6.7 1.5e-07 31.0 0.1 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53681.1 - 3.2e-66 219.6 26.2 1.9e-10 40.9 0.1 9.2 2 2 8 10 10 10 10 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53681.1 - 5.5e-10 39.6 0.6 0.27 11.8 0.0 6.5 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53681.1 - 1e-08 34.6 22.6 0.53 10.4 0.1 10.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53681.1 - 1.1e-08 34.6 30.3 0.096 12.5 0.1 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53681.1 - 1.9e-08 33.8 34.2 0.18 12.0 0.1 11.6 13 0 0 13 13 13 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK53681.1 - 4.7e-08 33.1 8.0 0.0037 17.5 0.1 7.1 7 1 2 9 9 8 2 Anaphase-promoting complex, cyclosome, subunit 3 Rapsyn_N PF10579.9 KIK53681.1 - 3.4e-07 30.2 1.6 0.2 11.8 0.0 7.2 5 2 3 8 8 8 1 Rapsyn N-terminal myristoylation and linker region TPR_8 PF13181.6 KIK53681.1 - 1.1e-06 28.4 22.3 1.9 8.9 0.1 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK53681.1 - 1.9e-06 27.5 9.2 0.037 13.4 1.2 5.8 2 2 1 4 4 4 2 MalT-like TPR region Zincin_2 PF10103.9 KIK53681.1 - 3.8e-05 23.1 0.0 1.4 8.1 0.0 3.8 2 2 1 3 3 3 1 Zincin-like metallopeptidase SRP_TPR_like PF17004.5 KIK53681.1 - 0.00029 20.8 1.4 1.3 9.0 0.0 5.4 5 1 3 8 8 5 1 Putative TPR-like repeat TPR_16 PF13432.6 KIK53681.1 - 0.0011 19.5 1.0 46 4.8 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 KIK53681.1 - 0.0049 17.0 6.1 44 4.6 0.9 6.7 8 0 0 8 8 6 0 PPR repeat TPR_9 PF13371.6 KIK53681.1 - 0.0056 16.8 0.8 3.1 8.0 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK53681.1 - 0.0069 16.9 0.1 48 5.0 0.0 5.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Titin_Ig-rpts PF06582.12 KIK53681.1 - 0.02 14.8 7.8 14 5.7 0.1 5.6 5 0 0 5 5 5 0 Titin repeat Vps39_1 PF10366.9 KIK53681.1 - 0.027 14.8 1.3 2.6 8.4 0.0 4.2 3 1 2 5 5 4 0 Vacuolar sorting protein 39 domain 1 TPR_6 PF13174.6 KIK53681.1 - 0.034 14.8 5.0 1.5e+02 3.3 0.0 7.6 9 1 0 9 9 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK53681.1 - 0.034 14.1 1.3 2.8 8.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat YqaH PF17448.2 KIK53681.1 - 0.037 14.3 0.0 67 3.9 0.0 4.8 4 1 1 5 5 5 0 Uncharacterized YqaH-like DUF2664 PF10867.8 KIK53681.1 - 0.058 13.8 5.7 29 5.2 0.0 5.6 7 0 0 7 7 5 0 Protein of unknown function (DUF2664) BTAD PF03704.17 KIK53681.1 - 0.081 13.3 1.2 14 6.1 0.0 3.9 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TrwB_AAD_bind PF10412.9 KIK53681.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KIK53681.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK53681.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Fis1_TPR_C PF14853.6 KIK53681.1 - 0.37 10.9 8.1 18 5.5 0.0 5.8 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KIK53681.1 - 0.95 9.2 14.5 33 4.3 0.1 6.7 7 0 0 7 7 7 0 TPR repeat TPR_17 PF13431.6 KIK53681.1 - 6.7 7.3 18.9 12 6.6 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 KIK53683.1 - 0.00019 20.7 0.3 0.0018 17.5 0.3 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK53683.1 - 0.00041 20.8 0.1 0.0021 18.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK53683.1 - 0.0083 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KIK53683.1 - 0.031 14.5 0.0 0.056 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIK53683.1 - 0.097 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KIK53683.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Aldedh PF00171.22 KIK53686.1 - 1.6e-22 79.6 0.0 2.1e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_16 PF13191.6 KIK53687.1 - 0.00059 20.3 0.0 0.00064 20.1 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK53687.1 - 0.013 14.5 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KIK53687.1 - 0.026 13.7 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KIK53687.1 - 0.06 13.3 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KIK53687.1 - 0.086 12.1 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KIK53687.1 - 0.13 11.9 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK53687.1 - 0.14 12.4 0.1 0.2 12.0 0.1 1.2 1 1 0 1 1 1 0 AAA domain DUF4402 PF14352.6 KIK53688.1 - 0.044 14.4 0.0 0.072 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) GntR PF00392.21 KIK53688.1 - 0.19 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family TPR_10 PF13374.6 KIK53690.1 - 9.8e-77 251.0 16.8 4.7e-08 32.6 0.0 12.3 11 2 0 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53690.1 - 1.3e-61 204.8 27.2 6e-12 45.7 0.3 7.9 2 2 5 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53690.1 - 1.1e-14 53.3 17.2 0.65 10.3 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK53690.1 - 4e-12 46.2 0.2 0.046 14.0 0.1 5.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK53690.1 - 3.3e-11 43.5 3.2 0.071 13.6 0.1 6.1 4 1 3 7 7 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK53690.1 - 3.8e-11 42.9 2.1 5.1 7.3 0.0 7.9 5 1 3 8 8 8 1 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.28 KIK53690.1 - 4.2e-10 39.0 22.3 0.13 12.1 0.1 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53690.1 - 5.1e-10 38.7 22.8 0.028 14.4 0.1 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK53690.1 - 8.6e-10 38.0 12.8 0.062 13.5 0.3 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK53690.1 - 2.5e-09 37.0 9.7 3e-05 23.5 3.4 3.5 1 1 3 4 4 4 3 MalT-like TPR region TPR_4 PF07721.14 KIK53690.1 - 2.2e-08 33.9 0.2 3.9 8.4 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF3856 PF12968.7 KIK53690.1 - 1.4e-06 28.4 1.0 0.86 9.7 0.2 5.7 4 2 1 6 6 6 1 Domain of Unknown Function (DUF3856) MCPVI PF02993.14 KIK53690.1 - 5.6e-06 26.3 1.6 6.7 6.5 0.1 5.4 1 1 2 5 5 5 0 Minor capsid protein VI TPR_16 PF13432.6 KIK53690.1 - 1.1e-05 26.0 3.1 5.8 7.7 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK53690.1 - 3.1e-05 24.2 6.2 15 6.0 0.0 7.3 4 3 4 8 8 8 0 Tetratricopeptide repeat DUF3400 PF11880.8 KIK53690.1 - 0.00016 21.2 0.3 39 3.9 0.0 6.2 8 0 0 8 8 6 0 Domain of unknown function (DUF3400) PPR PF01535.20 KIK53690.1 - 0.00028 20.9 4.9 17 5.9 0.0 6.5 7 0 0 7 7 5 0 PPR repeat TPR_14 PF13428.6 KIK53690.1 - 0.0003 21.3 2.2 9.9 7.3 0.0 5.3 7 0 0 7 7 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIK53690.1 - 0.00049 20.1 1.1 8.2 6.5 0.0 5.5 3 2 5 8 8 8 0 Putative TPR-like repeat YqaH PF17448.2 KIK53690.1 - 0.00084 19.6 0.8 8.9 6.7 0.0 4.7 3 2 2 6 6 6 0 Uncharacterized YqaH-like RPN7 PF10602.9 KIK53690.1 - 0.0021 17.8 1.0 14 5.3 0.0 4.5 3 2 0 4 4 4 0 26S proteasome subunit RPN7 Zincin_2 PF10103.9 KIK53690.1 - 0.0029 16.9 0.5 0.27 10.5 0.0 3.0 2 1 1 3 3 3 1 Zincin-like metallopeptidase Titin_Ig-rpts PF06582.12 KIK53690.1 - 0.0041 17.0 0.0 0.94 9.5 0.0 4.2 4 0 0 4 4 4 1 Titin repeat TPR_11 PF13414.6 KIK53690.1 - 0.0056 16.3 5.7 26 4.6 0.0 5.9 6 0 0 6 6 6 0 TPR repeat BTAD PF03704.17 KIK53690.1 - 0.0058 17.1 3.4 14 6.1 0.1 4.9 2 1 1 5 5 5 0 Bacterial transcriptional activator domain NARP1 PF12569.8 KIK53690.1 - 0.013 14.4 1.5 2.6 6.8 0.0 3.3 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Vps39_1 PF10366.9 KIK53690.1 - 0.026 14.8 5.9 0.82 10.0 0.0 4.3 3 2 2 5 5 5 0 Vacuolar sorting protein 39 domain 1 Fis1_TPR_C PF14853.6 KIK53690.1 - 0.034 14.2 4.0 19 5.4 0.0 5.6 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Foie-gras_1 PF11817.8 KIK53690.1 - 0.035 13.7 4.2 42 3.6 0.1 4.9 4 2 1 6 6 6 0 Foie gras liver health family 1 TPR_6 PF13174.6 KIK53690.1 - 0.035 14.7 10.0 22 5.9 0.0 7.0 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_5 PF12688.7 KIK53690.1 - 0.12 12.6 2.9 17 5.7 0.0 4.3 2 2 2 5 5 5 0 Tetratrico peptide repeat TetR_C_22 PF17928.1 KIK53690.1 - 0.24 11.8 1.6 42 4.5 0.1 4.0 4 1 1 5 5 4 0 Tetracyclin repressor-like, C-terminal domain TPR_17 PF13431.6 KIK53690.1 - 0.47 10.9 17.3 25 5.6 0.1 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat SPO22 PF08631.10 KIK53690.1 - 4 6.9 6.6 21 4.5 1.1 3.3 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_10 PF13374.6 KIK53692.1 - 3.3e-76 249.3 0.1 3.4e-08 33.1 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53692.1 - 1.8e-59 198.0 13.4 7e-12 45.5 0.0 8.1 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53692.1 - 1.8e-11 43.4 14.9 0.14 12.0 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53692.1 - 2e-11 43.0 15.9 1.3 9.3 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK53692.1 - 3.8e-09 36.5 0.4 0.052 13.6 0.0 6.4 3 2 4 7 7 6 1 Rapsyn N-terminal myristoylation and linker region TPR_8 PF13181.6 KIK53692.1 - 2.9e-07 30.2 6.1 3.1 8.2 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53692.1 - 7.9e-07 28.7 17.7 3.6 7.9 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat PPR PF01535.20 KIK53692.1 - 5.7e-06 26.2 0.3 49 4.5 0.0 7.2 7 0 0 7 7 7 0 PPR repeat ANAPC3 PF12895.7 KIK53692.1 - 1.3e-05 25.4 2.0 0.047 13.9 0.0 5.2 6 1 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK53692.1 - 3.7e-05 24.2 1.0 4.2 8.0 0.0 6.0 4 2 4 8 8 8 1 Tetratricopeptide repeat MCPVI PF02993.14 KIK53692.1 - 4.3e-05 23.4 0.5 5.1 6.9 0.1 5.0 1 1 4 5 5 5 2 Minor capsid protein VI DUF3856 PF12968.7 KIK53692.1 - 0.00052 20.1 3.5 3.8 7.6 0.0 6.2 4 1 3 7 7 6 1 Domain of Unknown Function (DUF3856) YqaH PF17448.2 KIK53692.1 - 0.0015 18.8 0.1 17 5.8 0.0 4.8 3 1 2 5 5 4 0 Uncharacterized YqaH-like Fis1_TPR_C PF14853.6 KIK53692.1 - 0.0016 18.5 0.1 7.1 6.8 0.0 4.9 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF3400 PF11880.8 KIK53692.1 - 0.0016 17.9 0.1 1.4e+02 2.1 0.0 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3400) Zincin_2 PF10103.9 KIK53692.1 - 0.0032 16.8 0.1 2.5 7.3 0.0 3.1 2 2 1 3 3 3 1 Zincin-like metallopeptidase Vps39_1 PF10366.9 KIK53692.1 - 0.008 16.4 1.5 2.6 8.3 0.0 4.3 4 1 1 5 5 4 1 Vacuolar sorting protein 39 domain 1 SRP_TPR_like PF17004.5 KIK53692.1 - 0.01 15.8 0.3 17 5.5 0.0 5.1 4 1 4 8 8 7 0 Putative TPR-like repeat DUF2664 PF10867.8 KIK53692.1 - 0.015 15.7 0.2 14 6.2 0.0 4.7 5 1 1 6 6 3 0 Protein of unknown function (DUF2664) BTAD PF03704.17 KIK53692.1 - 0.023 15.2 0.6 43 4.5 0.0 4.4 3 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KIK53692.1 - 0.035 13.5 7.8 1.6 8.0 0.3 3.5 2 1 2 4 4 4 0 MalT-like TPR region RIG-I_C PF18119.1 KIK53692.1 - 0.18 11.8 1.1 3.8 7.5 0.1 3.3 2 2 1 3 3 3 0 RIG-I receptor C-terminal domain Bcl-2 PF00452.19 KIK53693.1 - 0.14 12.8 0.3 0.87 10.3 0.0 2.2 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Tannase PF07519.11 KIK53696.1 - 8.8e-116 387.6 0.0 1e-115 387.3 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KIK53696.1 - 0.00012 21.4 0.0 0.0064 15.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK53696.1 - 0.015 14.9 0.4 0.073 12.7 0.2 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold IDO PF01231.18 KIK53697.1 - 2.8e-111 372.4 0.0 3.4e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.18 KIK53698.1 - 1.2e-115 386.8 0.0 1.3e-115 386.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KIK53698.1 - 0.059 12.1 0.0 8.1 5.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Mor PF08765.11 KIK53699.1 - 0.026 14.5 0.0 0.21 11.6 0.0 2.4 2 1 0 2 2 2 0 Mor transcription activator family DUF3387 PF11867.8 KIK53699.1 - 0.1 12.0 0.2 0.21 11.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3387) Alpha_kinase PF02816.18 KIK53701.1 - 2.8e-10 40.6 0.0 3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Asp PF00026.23 KIK53702.1 - 2.9e-47 161.6 6.1 8.4e-47 160.1 6.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK53702.1 - 1.2e-08 35.4 2.2 0.00044 20.5 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK53702.1 - 0.00095 19.8 1.2 0.07 13.8 0.3 2.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK53702.1 - 0.061 13.9 0.4 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease adh_short PF00106.25 KIK53703.1 - 1.8e-36 125.5 0.0 2.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK53703.1 - 1.4e-20 73.9 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK53703.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK53703.1 - 0.12 11.8 0.1 1.9 7.9 0.1 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIK53704.1 - 3.1e-05 23.5 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK53704.1 - 0.037 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK53705.1 - 1.6e-25 89.8 0.0 1.7e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK53705.1 - 7.9e-16 58.3 0.0 9.5e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK53705.1 - 0.00058 19.8 0.0 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 KR domain CBP PF12192.8 KIK53706.1 - 0.036 14.3 1.9 0.04 14.1 1.2 1.5 1 1 0 1 1 1 0 Fungal calcium binding protein Skp1 PF01466.19 KIK53707.1 - 4.6e-21 74.7 0.2 6.9e-21 74.1 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK53707.1 - 3.2e-15 56.0 0.3 9.3e-15 54.6 0.3 1.8 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Pkinase_Tyr PF07714.17 KIK53708.1 - 8e-34 117.1 0.0 2.3e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53708.1 - 1.7e-32 112.8 0.6 8.8e-32 110.5 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain RIO1 PF01163.22 KIK53708.1 - 0.0027 17.3 0.3 0.013 15.1 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIK53708.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tmemb_cc2 PF10267.9 KIK53708.1 - 0.17 11.0 6.4 0.38 9.8 6.1 1.5 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein KxDL PF10241.9 KIK53708.1 - 0.26 11.6 8.7 1.1 9.6 1.5 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein COG5 PF10392.9 KIK53708.1 - 0.36 11.0 5.1 0.15 12.2 0.9 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2203 PF09969.9 KIK53708.1 - 0.36 11.5 2.0 0.74 10.5 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Peroxidase_2 PF01328.17 KIK53709.1 - 2.3e-53 181.5 0.0 2.7e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF433 PF04255.14 KIK53709.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DLH PF01738.18 KIK53710.1 - 2.9e-19 69.5 0.0 3.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIK53710.1 - 0.016 14.7 0.3 0.36 10.3 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 KIK53712.1 - 1.9e-11 44.0 0.0 4.6e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Eno-Rase_FAD_bd PF07055.12 KIK53712.1 - 0.18 12.2 0.2 0.37 11.2 0.2 1.5 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DUF5637 PF18687.1 KIK53714.1 - 0.051 13.6 4.6 0.068 13.2 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5637) AcetylCoA_hyd_C PF13336.6 KIK53716.1 - 2.6e-43 147.6 0.0 4.4e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK53716.1 - 1.7e-40 139.1 0.0 2.9e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain WD40 PF00400.32 KIK53718.1 - 5.9e-102 330.7 71.8 5.7e-10 39.6 0.5 11.6 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53718.1 - 3e-27 94.7 16.8 0.012 15.9 0.1 10.9 1 1 10 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53718.1 - 2.2e-09 37.1 14.2 0.11 11.8 0.3 7.2 3 2 5 9 9 9 4 WD40-like domain Frtz PF11768.8 KIK53718.1 - 4.5e-09 35.2 1.9 1.2 7.4 0.0 7.0 1 1 7 9 9 9 3 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK53718.1 - 2.3e-08 34.1 0.0 6.5e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 KIK53718.1 - 2.6e-06 26.2 11.2 0.029 12.9 0.2 5.0 2 1 1 5 5 5 3 Cytochrome D1 heme domain AAA_16 PF13191.6 KIK53718.1 - 0.00011 22.7 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK53718.1 - 0.00046 19.5 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF727 PF05303.12 KIK53718.1 - 0.0007 19.6 0.5 22 5.1 0.0 5.6 2 2 4 8 8 8 0 Protein of unknown function (DUF727) Me-amine-dh_H PF06433.11 KIK53718.1 - 0.00086 18.3 0.3 0.85 8.4 0.0 3.8 2 2 1 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) PQQ_3 PF13570.6 KIK53718.1 - 0.0029 18.0 8.3 22 5.7 0.1 7.5 9 1 1 10 10 9 0 PQQ-like domain Ge1_WD40 PF16529.5 KIK53718.1 - 0.0097 14.9 12.7 6.6 5.6 0.1 7.1 1 1 6 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA PF00004.29 KIK53718.1 - 0.041 14.3 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK53718.1 - 0.046 14.1 0.1 0.49 10.8 0.0 2.9 3 0 0 3 3 1 0 RNA helicase PD40 PF07676.12 KIK53718.1 - 0.055 13.4 12.3 60 3.8 0.0 8.1 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat POLO_box PF00659.18 KIK53718.1 - 0.068 13.4 0.2 11 6.3 0.0 4.1 3 1 1 4 4 4 0 POLO box duplicated region AbiJ_NTD5 PF18865.1 KIK53718.1 - 0.093 12.5 0.5 6.5 6.6 0.0 4.2 7 0 0 7 7 6 0 AbiJ N-terminal domain 5 AlgF PF11182.8 KIK53718.1 - 0.11 12.3 0.6 8.2 6.2 0.0 3.8 5 0 0 5 5 5 0 Alginate O-acetyl transferase AlgF Trans_reg_C PF00486.28 KIK53718.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ABC_tran PF00005.27 KIK53718.1 - 0.18 12.3 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Coat_X PF07552.11 KIK53718.1 - 0.58 10.0 2.9 7.7 6.4 0.1 3.5 3 0 0 3 3 3 0 Spore Coat Protein X and V domain NB-ARC PF00931.22 KIK53720.1 - 8.8e-05 21.8 0.0 8.8e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KIK53720.1 - 0.0013 18.7 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK53720.1 - 0.0036 17.7 0.0 0.0036 17.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK53720.1 - 0.0091 16.4 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.20 KIK53720.1 - 0.028 14.3 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.32 KIK53721.1 - 1.6e-115 373.6 80.4 5e-11 43.0 0.1 12.8 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53721.1 - 5.5e-37 126.0 17.9 0.0015 18.8 0.1 11.6 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53721.1 - 1.4e-17 64.0 7.2 0.0022 17.4 0.0 7.5 3 3 5 8 8 8 7 WD40-like domain Cytochrom_D1 PF02239.16 KIK53721.1 - 4e-10 38.8 9.7 0.017 13.6 0.3 4.7 3 2 1 5 5 5 4 Cytochrome D1 heme domain Frtz PF11768.8 KIK53721.1 - 1.3e-09 36.9 0.7 1.1 7.5 0.0 7.8 2 2 9 11 11 11 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK53721.1 - 3.5e-09 36.9 16.0 0.66 10.5 0.1 10.2 12 0 0 12 12 12 2 PQQ-like domain Ge1_WD40 PF16529.5 KIK53721.1 - 1.3e-07 31.0 14.2 3.6 6.5 0.0 8.8 1 1 8 10 10 10 4 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4242 PF14026.6 KIK53721.1 - 0.00064 19.9 0.0 17 5.7 0.0 5.8 6 1 1 7 7 7 0 Protein of unknown function (DUF4242) Kelch_6 PF13964.6 KIK53721.1 - 0.0022 18.2 18.1 2.7 8.4 0.2 7.0 8 0 0 8 8 7 3 Kelch motif PQQ PF01011.21 KIK53721.1 - 0.0077 16.1 4.1 9.8 6.3 0.0 6.6 8 0 0 8 8 8 1 PQQ enzyme repeat DCX PF03607.17 KIK53721.1 - 0.083 13.0 0.7 5.3 7.2 0.0 3.8 3 0 0 3 3 3 0 Doublecortin PD40 PF07676.12 KIK53721.1 - 4.8 7.3 21.5 35 4.5 0.1 8.5 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat AcetylCoA_hyd_C PF13336.6 KIK53723.1 - 6.5e-36 123.6 0.0 7.5e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK53724.1 - 3.1e-24 84.8 5.8 1.6e-08 35.1 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53724.1 - 3.2e-11 43.4 0.6 0.002 18.4 0.1 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK53724.1 - 1.6e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK53724.1 - 1e-05 26.0 0.0 2.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK53724.1 - 0.00033 19.9 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain WD40_like PF17005.5 KIK53724.1 - 0.00079 18.8 0.3 0.018 14.4 0.1 2.3 1 1 1 2 2 2 1 WD40-like domain NTPase_1 PF03266.15 KIK53724.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KIK53724.1 - 0.014 15.8 0.0 0.075 13.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 KIK53724.1 - 0.025 13.5 0.7 13 4.7 0.0 3.0 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APS_kinase PF01583.20 KIK53724.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK53724.1 - 0.044 14.2 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Frtz PF11768.8 KIK53724.1 - 0.055 11.8 0.0 0.43 8.8 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK53726.1 - 1.5e-126 408.5 97.8 1.5e-09 38.3 2.9 14.9 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53726.1 - 2.8e-35 120.5 25.4 0.036 14.4 0.1 13.5 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53726.1 - 1.2e-12 47.8 20.6 0.044 13.1 0.1 8.3 6 2 1 9 9 9 5 WD40-like domain Frtz PF11768.8 KIK53726.1 - 2.9e-07 29.2 4.2 13 3.9 0.0 7.6 1 1 7 9 9 9 2 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK53726.1 - 7.7e-07 28.0 13.4 0.095 11.2 0.2 5.0 3 1 0 5 5 5 4 Cytochrome D1 heme domain NACHT PF05729.12 KIK53726.1 - 1.2e-06 28.6 0.0 3.4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK53726.1 - 0.00021 21.7 0.0 0.00056 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK53726.1 - 0.0021 17.3 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PQQ_3 PF13570.6 KIK53726.1 - 0.003 18.0 13.6 1.7 9.2 0.2 8.1 9 0 0 9 9 9 1 PQQ-like domain RNA_helicase PF00910.22 KIK53726.1 - 0.033 14.6 0.1 0.75 10.2 0.0 3.4 3 0 0 3 3 2 0 RNA helicase AAA PF00004.29 KIK53726.1 - 0.063 13.7 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KIK53726.1 - 0.24 11.4 13.7 69 3.5 0.1 9.2 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Inhibitor_I66 PF16850.5 KIK53727.1 - 1.8e-27 96.0 0.1 9.6e-27 93.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I66 Allexi_40kDa PF05549.11 KIK53728.1 - 0.12 11.9 1.3 0.2 11.1 1.3 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1096 PF06493.11 KIK53728.1 - 0.14 12.7 4.8 0.33 11.4 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1096) Phage_lambda_P PF06992.11 KIK53728.1 - 0.57 9.9 4.8 0.17 11.6 0.4 2.1 2 1 0 2 2 2 0 Replication protein P Transposase_21 PF02992.14 KIK53729.1 - 3.5e-10 39.5 2.0 2.6e-09 36.6 0.0 2.8 3 0 0 3 3 3 1 Transposase family tnp2 DUF4218 PF13960.6 KIK53729.1 - 0.01 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) AAA_16 PF13191.6 KIK53730.1 - 0.00011 22.6 0.0 0.00013 22.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK53730.1 - 0.0044 17.0 0.0 0.0071 16.3 0.0 1.4 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 KIK53730.1 - 0.0048 16.8 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK53730.1 - 0.0069 16.8 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK53730.1 - 0.01 15.7 0.1 0.021 14.7 0.0 1.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK53730.1 - 0.012 14.9 0.0 0.015 14.5 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KIK53730.1 - 0.053 12.8 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KIK53730.1 - 0.098 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK53730.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 KIK53730.1 - 0.13 12.3 0.4 0.25 11.4 0.1 1.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KIK53730.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK53731.1 - 6.7e-53 175.5 39.5 7.5e-10 39.2 0.1 10.5 10 1 1 11 11 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53731.1 - 6.3e-27 93.7 1.0 0.23 11.8 0.0 9.9 1 1 7 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53731.1 - 1.6e-13 50.3 2.7 0.15 11.0 0.1 7.6 3 3 5 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK53731.1 - 4.4e-11 41.8 0.0 0.017 13.5 0.0 4.1 4 0 0 4 4 4 4 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK53731.1 - 2.3e-09 36.9 3.8 1.3 9.1 0.0 7.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK53731.1 - 5.1e-06 26.0 6.6 14 4.9 0.0 7.8 2 2 7 9 9 9 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK53731.1 - 0.00015 20.6 3.0 0.68 8.5 0.1 5.3 3 2 1 4 4 4 1 Nucleoporin Nup120/160 MinC_C PF03775.16 KIK53731.1 - 0.0008 19.4 0.1 0.05 13.6 0.0 2.8 3 0 0 3 3 3 1 Septum formation inhibitor MinC, C-terminal domain WD40_3 PF15911.5 KIK53731.1 - 0.0014 18.6 0.2 5.4 7.1 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Utp8 PF10395.9 KIK53731.1 - 0.0028 16.2 0.0 0.78 8.2 0.0 3.0 2 2 1 3 3 3 1 Utp8 family tify PF06200.14 KIK53731.1 - 0.0093 15.3 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 tify domain 3-dmu-9_3-mt PF06983.13 KIK53731.1 - 0.026 15.0 0.0 7.8 7.1 0.0 4.0 4 0 0 4 4 4 0 3-demethylubiquinone-9 3-methyltransferase IKI3 PF04762.12 KIK53731.1 - 0.036 12.1 0.1 3.2 5.6 0.0 2.3 1 1 0 2 2 2 0 IKI3 family Phytase-like PF13449.6 KIK53731.1 - 0.08 12.9 0.1 7.6 6.4 0.1 3.1 3 1 0 3 3 3 0 Esterase-like activity of phytase DpaA_N PF16924.5 KIK53731.1 - 0.12 12.5 0.0 65 3.7 0.0 3.8 3 1 1 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain DUF4072 PF13284.6 KIK53731.1 - 0.2 12.1 0.4 27 5.3 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) PALB2_WD40 PF16756.5 KIK53731.1 - 0.83 8.5 3.4 17 4.2 0.0 3.8 5 1 1 6 6 6 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK53733.1 - 9.9e-30 102.2 10.8 2.4e-06 28.2 0.1 8.2 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53733.1 - 5.6e-18 65.0 0.4 0.034 14.4 0.1 7.0 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK53733.1 - 1.5e-12 47.2 1.7 0.0057 15.7 0.0 5.2 3 1 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK53733.1 - 5.7e-11 42.1 1.1 0.98 9.4 0.0 7.6 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK53733.1 - 4.4e-10 39.8 0.1 2.9e-05 24.1 0.2 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK53733.1 - 1.2e-05 24.2 1.5 1.4 7.4 0.0 5.5 4 1 2 6 6 6 1 Nucleoporin Nup120/160 Frtz PF11768.8 KIK53733.1 - 1.7e-05 23.4 0.0 0.00023 19.6 0.0 2.3 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK53733.1 - 0.00014 21.4 1.0 14 4.9 0.0 5.9 3 2 4 7 7 7 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KIK53733.1 - 0.0088 15.0 0.2 0.68 8.8 0.1 3.1 3 2 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain NAGPA PF09992.9 KIK53733.1 - 0.022 15.0 0.6 1.1 9.4 0.0 2.5 2 1 0 2 2 2 0 Phosphodiester glycosidase DUF3261 PF11659.8 KIK53733.1 - 0.043 13.7 0.0 7.4 6.4 0.0 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF3261) WD40_3 PF15911.5 KIK53733.1 - 0.057 13.4 0.0 3.8 7.6 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat TruB_C PF09142.11 KIK53733.1 - 0.08 12.7 0.0 2.6 7.9 0.0 3.3 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal MinC_C PF03775.16 KIK53733.1 - 0.17 11.8 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Pkinase PF00069.25 KIK53735.1 - 5.2e-11 42.4 0.0 8.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53735.1 - 1.2e-10 41.1 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YchF-GTPase_C PF06071.13 KIK53735.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Kdo PF06293.14 KIK53735.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 KIK53735.1 - 0.16 12.7 0.3 0.16 12.7 0.3 2.0 2 0 0 2 2 2 0 Sel1 repeat Pkinase_Tyr PF07714.17 KIK53736.1 - 3.1e-22 79.1 0.0 5.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK53736.1 - 2.3e-19 69.8 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KIK53736.1 - 1.1e-17 64.4 0.3 2.2e-07 31.3 0.0 5.9 5 1 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK53736.1 - 2.3e-16 58.2 7.5 0.016 15.7 0.0 8.7 9 0 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.6 KIK53736.1 - 4.4e-16 59.0 5.1 5.7e-08 33.1 0.1 7.0 7 1 0 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK53736.1 - 2e-10 40.7 0.9 0.012 15.9 0.0 5.7 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK53736.1 - 3.9e-07 30.2 14.9 0.78 10.3 0.1 8.5 10 0 0 10 10 10 3 Ankyrin repeat RuvA_C PF07499.13 KIK53736.1 - 0.094 13.2 1.8 11 6.6 0.0 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain ABC_membrane PF00664.23 KIK53737.1 - 3.9e-30 105.4 25.0 6.6e-19 68.6 13.2 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK53737.1 - 1.1e-29 103.7 0.1 3.7e-14 53.4 0.0 3.2 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK53737.1 - 6.6e-08 32.3 0.2 0.052 13.0 0.0 3.3 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK53737.1 - 0.0043 16.8 0.8 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KIK53737.1 - 0.0058 15.7 0.0 0.048 12.7 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 KIK53737.1 - 0.082 12.7 2.9 11 5.8 0.4 3.2 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 KIK53737.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_23 PF13476.6 KIK53737.1 - 0.17 12.4 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsX PF02687.21 KIK53738.1 - 0.0084 16.6 2.9 0.26 11.8 0.2 2.7 3 1 0 3 3 3 2 FtsX-like permease family Baculo_E56 PF04639.12 KIK53740.1 - 0.24 10.6 0.5 0.42 9.8 0.5 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope ABC_membrane PF00664.23 KIK53742.1 - 1.4e-44 152.8 28.9 3.4e-22 79.4 9.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK53742.1 - 1.5e-40 138.8 0.0 4.2e-24 85.6 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK53742.1 - 4.6e-07 29.5 3.9 0.095 12.1 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIK53742.1 - 4e-06 26.5 0.0 0.09 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK53742.1 - 9.9e-06 26.0 0.1 0.15 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KIK53742.1 - 1.2e-05 24.5 0.0 0.0073 15.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KIK53742.1 - 4.7e-05 23.0 0.4 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK53742.1 - 0.0001 22.9 0.4 0.013 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK53742.1 - 0.0021 18.3 0.5 2.2 8.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK53742.1 - 0.0028 17.8 1.3 0.035 14.2 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 KIK53742.1 - 0.0036 17.2 8.9 0.13 12.1 0.5 4.1 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KIK53742.1 - 0.0054 16.3 0.1 3.4 7.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KIK53742.1 - 0.0098 16.0 0.4 0.76 9.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KIK53742.1 - 0.015 15.0 0.2 2.2 8.0 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KIK53742.1 - 0.017 15.0 0.0 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 KIK53742.1 - 0.018 14.5 0.5 3.4 7.0 0.1 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.6 KIK53742.1 - 0.027 15.0 0.0 5.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK53742.1 - 0.03 14.4 0.5 7.2 6.6 0.2 2.4 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 KIK53742.1 - 0.071 13.5 0.0 2.3 8.7 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK53742.1 - 0.077 12.7 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK53742.1 - 0.08 12.5 1.9 0.54 9.8 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 KIK53742.1 - 0.095 12.5 0.0 14 5.4 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 KIK53742.1 - 0.098 11.4 0.1 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF2075 PF09848.9 KIK53742.1 - 0.14 11.3 0.1 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KIK53742.1 - 0.26 11.2 1.2 18 5.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain DUF2207 PF09972.9 KIK53742.1 - 6.7 5.3 6.6 0.71 8.6 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TPR_10 PF13374.6 KIK53743.1 - 3.3e-115 373.3 10.2 1.6e-12 46.8 0.1 11.2 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53743.1 - 1.1e-85 281.9 25.9 2.4e-14 53.4 0.0 8.8 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK53743.1 - 2.1e-24 86.6 17.6 6.5e-09 35.6 1.4 4.7 1 1 4 5 5 5 4 MalT-like TPR region TPR_17 PF13431.6 KIK53743.1 - 2e-22 77.9 6.6 0.21 12.1 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_4 PF07721.14 KIK53743.1 - 4e-20 70.3 0.0 0.1 13.3 0.0 9.1 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53743.1 - 6.1e-18 63.4 22.0 0.39 11.0 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53743.1 - 2.4e-17 61.9 22.0 0.31 11.0 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53743.1 - 1.6e-16 59.0 16.7 1.9 8.7 0.1 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK53743.1 - 5.5e-16 57.4 21.8 0.53 10.6 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIK53743.1 - 4.8e-12 46.3 0.0 0.64 10.7 0.0 6.5 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53743.1 - 1.3e-11 44.8 0.8 1.2 9.7 0.0 7.6 3 2 6 9 9 9 3 Tetratricopeptide repeat TPR_3 PF07720.12 KIK53743.1 - 3.1e-05 23.8 8.3 17 5.6 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK53743.1 - 7.1e-05 22.6 9.2 7.6 6.2 0.0 6.5 2 2 6 8 8 8 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 KIK53743.1 - 0.0014 19.3 8.2 1.1e+02 4.1 0.0 8.5 11 0 0 11 11 9 0 Tetratricopeptide repeat SSI PF00720.17 KIK53743.1 - 0.0021 18.0 1.9 2.6 8.1 0.0 4.5 3 1 1 4 4 4 1 Subtilisin inhibitor-like PPR PF01535.20 KIK53743.1 - 0.0022 18.1 22.1 43 4.7 0.1 9.7 10 0 0 10 10 10 0 PPR repeat ANAPC3 PF12895.7 KIK53743.1 - 0.0046 17.1 4.4 0.091 13.0 0.1 4.6 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Meckelin PF09773.9 KIK53743.1 - 0.039 12.1 2.1 13 3.7 0.1 3.7 1 1 1 3 3 3 0 Meckelin (Transmembrane protein 67) TPR_9 PF13371.6 KIK53743.1 - 0.12 12.5 0.0 34 4.7 0.0 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat Spore_YpjB PF09577.10 KIK53743.1 - 0.29 10.9 1.3 55 3.4 0.0 3.6 3 2 2 5 5 5 0 Sporulation protein YpjB (SpoYpjB) WT1 PF02165.15 KIK53743.1 - 0.44 9.7 1.6 12 5.0 0.0 3.2 3 1 0 3 3 3 0 Wilm's tumour protein DUF1897 PF09005.10 KIK53743.1 - 0.51 9.9 18.1 3.9 7.0 0.0 8.0 10 0 0 10 10 10 0 Domain of unknown function (DUF1897) ABC_membrane PF00664.23 KIK53745.1 - 2.7e-104 348.7 25.4 1.5e-55 188.8 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK53745.1 - 1.1e-68 230.0 0.0 4.1e-34 118.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK53745.1 - 2e-13 50.3 2.2 8.8e-05 22.0 0.1 4.1 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIK53745.1 - 2.2e-08 33.3 0.4 0.0018 17.1 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KIK53745.1 - 5.3e-07 29.3 0.1 0.042 13.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK53745.1 - 8.6e-07 29.0 0.0 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KIK53745.1 - 9.7e-07 28.3 0.1 0.035 13.4 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_22 PF13401.6 KIK53745.1 - 2.7e-06 27.7 1.4 0.042 14.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK53745.1 - 4.4e-06 27.2 2.6 0.0097 16.3 0.0 3.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 KIK53745.1 - 1.4e-05 25.0 0.1 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KIK53745.1 - 8.9e-05 22.4 0.1 0.7 9.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK53745.1 - 0.00015 22.3 0.1 0.2 12.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KIK53745.1 - 0.00031 20.4 0.8 0.64 9.6 0.1 2.9 4 0 0 4 4 2 2 AAA domain AAA_30 PF13604.6 KIK53745.1 - 0.00037 20.3 0.9 1.7 8.3 0.2 3.5 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 KIK53745.1 - 0.00043 19.6 0.0 0.046 12.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA PF00004.29 KIK53745.1 - 0.0013 19.2 2.9 0.52 10.7 0.4 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK53745.1 - 0.0035 16.6 0.0 0.06 12.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 KIK53745.1 - 0.0041 17.3 3.3 2.5 8.4 0.4 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KIK53745.1 - 0.0089 15.6 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KIK53745.1 - 0.018 15.1 0.0 4 7.5 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KIK53745.1 - 0.02 15.0 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK53745.1 - 0.026 14.3 0.1 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK53745.1 - 0.027 14.5 0.2 3.1 7.8 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KIK53745.1 - 0.036 13.2 0.1 7.6 5.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KIK53745.1 - 0.044 13.9 2.6 19 5.3 0.1 4.3 5 0 0 5 5 5 0 Helicase HerA, central domain APS_kinase PF01583.20 KIK53745.1 - 0.045 13.6 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK53745.1 - 0.053 13.9 0.0 5.5 7.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 KIK53745.1 - 0.073 13.6 0.0 21 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KIK53745.1 - 0.085 12.6 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KIK53745.1 - 0.14 12.6 0.0 40 4.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIK53745.1 - 0.16 11.9 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KIK53745.1 - 0.2 11.5 0.4 5.9 6.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain IGPD PF00475.18 KIK53746.1 - 0.0064 16.8 0.7 0.92 9.8 0.2 2.2 1 1 1 2 2 2 2 Imidazoleglycerol-phosphate dehydratase Phage-tail_2 PF09096.10 KIK53746.1 - 0.35 10.8 2.0 9.6 6.1 0.2 2.3 1 1 1 2 2 2 0 Baseplate structural protein, domain 2 Ufm1 PF03671.14 KIK53746.1 - 1.8 8.7 5.2 13 6.0 0.4 2.5 1 1 1 2 2 2 0 Ubiquitin fold modifier 1 protein AAA-ATPase_like PF09820.9 KIK53747.1 - 5.9e-12 45.6 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Predicted AAA-ATPase TPR_10 PF13374.6 KIK53748.1 - 2.5e-134 434.1 17.5 4.7e-12 45.4 0.0 13.0 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53748.1 - 1.2e-116 381.2 59.9 1.1e-14 54.4 0.1 10.0 1 1 11 12 12 12 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK53748.1 - 6.6e-33 114.5 28.9 4.3e-10 39.5 6.6 4.3 2 1 2 4 4 4 4 MalT-like TPR region TPR_7 PF13176.6 KIK53748.1 - 3e-31 105.1 27.2 0.037 14.1 0.1 13.0 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53748.1 - 1.5e-24 84.0 32.7 0.029 14.5 0.1 12.9 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_4 PF07721.14 KIK53748.1 - 3.5e-24 82.9 2.1 0.77 10.6 0.0 11.9 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53748.1 - 3.3e-20 71.0 31.8 0.26 11.2 0.0 12.8 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIK53748.1 - 4.6e-20 70.1 37.8 0.22 11.8 0.1 12.8 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53748.1 - 1.2e-17 64.2 24.9 0.011 16.2 1.2 10.0 3 3 8 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIK53748.1 - 9.1e-17 61.4 5.5 1.1 9.9 0.0 10.7 11 1 1 12 12 12 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK53748.1 - 4.4e-16 58.2 19.5 5.6 8.1 0.1 12.0 12 1 1 13 13 12 2 Tetratricopeptide repeat PPR PF01535.20 KIK53748.1 - 6.3e-10 38.6 23.0 6.3 7.3 0.1 12.3 13 0 0 13 13 13 1 PPR repeat TPR_17 PF13431.6 KIK53748.1 - 8.7e-10 38.3 25.7 1.5 9.4 0.0 11.2 13 0 0 13 13 13 3 Tetratricopeptide repeat RPN7 PF10602.9 KIK53748.1 - 2.5e-06 27.3 16.1 0.96 9.1 0.4 8.2 2 1 6 9 9 9 2 26S proteasome subunit RPN7 DUF1897 PF09005.10 KIK53748.1 - 0.0021 17.5 3.1 51 3.5 0.0 6.2 6 0 0 6 6 6 0 Domain of unknown function (DUF1897) Trans_reg_C PF00486.28 KIK53748.1 - 0.016 15.3 1.6 22 5.2 0.0 4.7 5 1 1 6 6 5 0 Transcriptional regulatory protein, C terminal EP400_N PF15790.5 KIK53748.1 - 0.18 10.6 1.6 18 4.0 0.1 3.5 2 2 3 5 5 5 0 E1A-binding protein p400, N-terminal PPR_1 PF12854.7 KIK53748.1 - 0.23 11.2 33.1 11 5.8 0.2 10.7 13 0 0 13 13 13 0 PPR repeat ANAPC3 PF12895.7 KIK53748.1 - 0.36 11.1 18.2 11 6.3 1.1 7.1 2 1 5 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3660 PF12398.8 KIK53748.1 - 1.6 8.9 6.3 25 5.0 0.1 5.2 7 0 0 7 7 6 0 Receptor serine/threonine kinase AA_permease_2 PF13520.6 KIK53749.1 - 9.3e-78 261.9 39.6 1.2e-77 261.6 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK53749.1 - 5.3e-12 45.1 32.1 8.2e-12 44.5 32.1 1.3 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KIK53750.1 - 4.8e-14 52.1 56.9 4.8e-14 52.1 56.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3437 PF11919.8 KIK53751.1 - 0.18 11.8 1.0 0.4 10.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) TPR_10 PF13374.6 KIK53752.1 - 2.4e-148 478.6 27.8 1.3e-11 44.0 0.0 16.2 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_12 PF13424.6 KIK53752.1 - 2e-107 351.6 33.6 1.8e-14 53.7 0.2 11.1 3 2 8 12 12 12 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK53752.1 - 1.1e-40 140.0 56.6 3.5e-12 46.3 5.3 4.8 1 1 5 6 6 6 6 MalT-like TPR region TPR_4 PF07721.14 KIK53752.1 - 3.2e-29 98.5 0.0 1.1 10.1 0.0 14.0 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK53752.1 - 5.2e-26 89.1 22.8 0.16 12.4 0.1 14.2 14 1 1 15 15 15 8 Tetratricopeptide repeat TPR_7 PF13176.6 KIK53752.1 - 6.3e-22 75.9 27.4 1.1 9.5 0.0 13.8 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 KIK53752.1 - 3e-20 70.7 48.5 0.26 11.6 0.3 13.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 KIK53752.1 - 3.8e-20 70.3 41.3 0.12 12.6 0.4 14.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIK53752.1 - 6.8e-18 65.0 22.0 0.069 13.7 0.1 11.8 3 3 10 14 14 14 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK53752.1 - 3.1e-17 61.6 47.1 0.48 10.3 0.1 14.2 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIK53752.1 - 1.5e-10 41.6 1.6 2.5 8.8 0.1 9.4 7 2 4 11 11 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK53752.1 - 5.1e-07 30.0 24.5 20 6.4 0.0 12.4 13 0 0 13 13 12 0 Tetratricopeptide repeat ATPgrasp_N PF18130.1 KIK53752.1 - 0.0063 17.0 0.2 12 6.5 0.0 4.4 4 0 0 4 4 4 0 ATP-grasp N-terminal domain TPR_20 PF14561.6 KIK53752.1 - 0.037 14.4 8.1 54 4.2 0.1 6.8 6 3 1 7 7 6 0 Tetratricopeptide repeat HicB_lk_antitox PF15919.5 KIK53752.1 - 0.068 13.3 0.0 3.5 7.8 0.0 3.6 3 1 1 4 4 4 0 HicB_like antitoxin of bacterial toxin-antitoxin system Spore_YpjB PF09577.10 KIK53752.1 - 0.36 10.6 4.1 13 5.5 0.0 4.2 4 0 0 4 4 4 0 Sporulation protein YpjB (SpoYpjB) PPR PF01535.20 KIK53752.1 - 0.9 9.9 40.8 29 5.2 0.1 12.8 14 0 0 14 14 14 0 PPR repeat EP400_N PF15790.5 KIK53752.1 - 1 8.1 3.7 14 4.4 0.0 3.9 3 1 1 4 4 4 0 E1A-binding protein p400, N-terminal TPR_3 PF07720.12 KIK53752.1 - 6.8 6.8 16.6 29 4.8 0.1 7.1 9 0 0 9 9 8 0 Tetratricopeptide repeat Hydrophobin PF01185.18 KIK53753.1 - 4.4e-16 59.3 5.7 5.2e-16 59.0 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Phage_Mu_Gam PF07352.12 KIK53754.1 - 0.074 13.0 0.4 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein COG2 PF06148.11 KIK53754.1 - 1.5 8.9 4.4 31 4.6 0.3 3.4 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KIK53755.1 - 0.055 13.5 1.0 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KIK53755.1 - 0.13 11.9 6.1 1.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 KIK53755.1 - 0.23 11.0 3.6 0.5 9.9 2.8 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF1043 PF06295.12 KIK53755.1 - 0.55 10.3 2.9 1.4 8.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Hydrophobin PF01185.18 KIK53756.1 - 1.1e-25 90.1 9.8 1.3e-25 89.8 9.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.16 KIK53757.1 - 5.3e-27 94.7 32.6 5.3e-27 94.7 32.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK53757.1 - 1.5e-05 23.7 0.5 2.2e-05 23.1 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK53757.1 - 0.0001 21.3 5.0 0.0001 21.3 5.0 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter Hydrophobin PF01185.18 KIK53758.1 - 6.9e-25 87.5 11.6 8.2e-25 87.2 11.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Exo70 PF03081.15 KIK53759.1 - 6e-40 137.5 0.1 8.8e-40 136.9 0.1 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Hydrophobin PF01185.18 KIK53760.1 - 1.9e-24 86.1 9.5 2.3e-24 85.8 9.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK53762.1 - 9.5e-25 87.1 10.0 1.1e-24 86.8 10.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4562 PF15123.6 KIK53763.1 - 0.047 13.6 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) NOA36 PF06524.12 KIK53763.1 - 2.8 7.2 6.1 3.4 6.9 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nodulin PF02451.15 KIK53764.1 - 0.05 13.1 0.1 0.059 12.8 0.1 1.1 1 0 0 1 1 1 0 Nodulin Hydrophobin PF01185.18 KIK53765.1 - 2.8e-25 88.8 9.1 3.3e-25 88.5 9.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK53766.1 - 3.3e-25 88.5 10.4 4.2e-25 88.2 10.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK53767.1 - 3.3e-25 88.5 8.1 3.9e-25 88.3 8.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin TMEM154 PF15102.6 KIK53768.1 - 0.0097 15.8 0.2 0.017 15.0 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4501 PF14946.6 KIK53768.1 - 0.034 14.2 0.3 0.048 13.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) EphA2_TM PF14575.6 KIK53768.1 - 0.042 14.7 0.0 0.069 14.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KIK53768.1 - 0.1 12.4 0.7 0.15 11.8 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4381 PF14316.6 KIK53768.1 - 0.19 11.9 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ANAPC4_WD40 PF12894.7 KIK53769.1 - 0.0017 18.6 0.0 0.32 11.3 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK53769.1 - 0.025 15.4 0.0 3 8.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Hydrophobin PF01185.18 KIK53770.1 - 3.9e-22 78.7 8.4 4.7e-22 78.4 8.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF2976 PF11190.8 KIK53770.1 - 0.06 13.2 0.4 0.092 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Hydrophobin PF01185.18 KIK53773.1 - 2e-24 86.0 8.7 2.5e-24 85.7 8.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK53774.1 - 2.1e-17 63.5 4.9 3.3e-17 62.9 4.9 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK53775.1 - 2e-20 73.2 9.4 2.3e-20 73.0 9.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK53777.1 - 3.6e-25 88.4 9.2 4.3e-25 88.2 9.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF2976 PF11190.8 KIK53777.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) ApoL PF05461.11 KIK53777.1 - 0.24 10.7 1.9 0.3 10.4 1.9 1.1 1 0 0 1 1 1 0 Apolipoprotein L RNA_lig_T4_1 PF09511.10 KIK53778.1 - 8.4e-85 284.1 0.0 1.4e-84 283.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 KIK53778.1 - 1.5e-26 93.4 0.0 1.2e-25 90.4 0.0 2.2 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 KIK53778.1 - 5.7e-23 81.8 0.0 1.1e-22 80.9 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain Ank_4 PF13637.6 KIK53779.1 - 6.2e-12 45.8 0.0 1.1e-07 32.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK53779.1 - 1.5e-07 31.5 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KIK53779.1 - 7.3e-07 29.7 0.1 1.7e-06 28.5 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK53779.1 - 1e-06 28.6 0.0 0.0073 16.7 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIK53779.1 - 0.0011 19.2 0.0 0.0048 17.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK53780.1 - 2.5e-12 47.0 0.0 7.9e-10 39.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK53780.1 - 6.4e-12 45.9 0.2 7.3e-12 45.7 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK53780.1 - 2.3e-10 40.5 1.0 6.7e-05 23.1 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK53780.1 - 4.9e-09 35.7 0.0 0.00062 20.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK53780.1 - 7.7e-09 35.7 0.2 5.9e-06 26.5 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF4766 PF15973.5 KIK53780.1 - 0.046 14.3 1.9 0.091 13.3 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) CholecysA-Rec_N PF09193.10 KIK53780.1 - 0.18 11.9 0.0 1.5 8.9 0.0 2.0 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal SMP PF04927.12 KIK53780.1 - 0.29 11.6 3.4 1.3 9.6 0.4 2.2 2 0 0 2 2 2 0 Seed maturation protein DUF1843 PF08898.10 KIK53780.1 - 0.52 10.8 4.5 4.5 7.9 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Ank_4 PF13637.6 KIK53781.1 - 2.3e-19 69.5 0.8 6.3e-09 36.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK53781.1 - 4.8e-11 43.1 0.1 4.8e-11 43.1 0.1 1.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK53781.1 - 1.1e-09 38.2 7.4 0.00029 21.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIK53781.1 - 1.1e-08 35.2 0.4 1.3e-05 25.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK53781.1 - 1.4e-07 31.2 0.0 0.027 15.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat MtrH PF02007.18 KIK53781.1 - 0.0023 17.1 0.4 0.18 10.9 0.1 2.1 1 1 1 2 2 2 2 Tetrahydromethanopterin S-methyltransferase MtrH subunit RNA_lig_T4_1 PF09511.10 KIK53782.1 - 8.8e-85 284.0 0.0 1.4e-84 283.3 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 KIK53782.1 - 1.8e-26 93.1 0.0 1.5e-25 90.2 0.0 2.2 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 KIK53782.1 - 3.2e-22 79.4 0.0 6.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain FAR1 PF03101.15 KIK53783.1 - 0.065 13.9 4.6 0.13 13.0 4.6 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain GRP PF07172.11 KIK53785.1 - 0.017 15.8 5.6 0.031 15.0 5.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 KIK53785.1 - 6.3 7.4 8.6 12 6.5 8.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RIFIN PF02009.16 KIK53786.1 - 0.004 17.1 0.1 0.0071 16.3 0.0 1.4 2 0 0 2 2 2 1 Rifin Amnionless PF14828.6 KIK53786.1 - 0.018 13.9 0.1 0.022 13.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless Mid2 PF04478.12 KIK53786.1 - 0.021 14.6 1.4 0.038 13.8 1.4 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KIK53786.1 - 0.022 14.7 2.9 0.026 14.4 2.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 KIK53786.1 - 0.03 13.9 0.2 0.044 13.3 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame PTP_tm PF18861.1 KIK53786.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J AI-2E_transport PF01594.16 KIK53786.1 - 0.066 12.4 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 AI-2E family transporter Alpha_GJ PF03229.13 KIK53786.1 - 0.071 13.7 4.0 0.12 12.9 4.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Hydrophobin PF01185.18 KIK53787.1 - 1.4e-24 86.5 10.1 1.7e-24 86.2 10.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4418 PF14387.6 KIK53787.1 - 0.38 11.0 5.7 0.66 10.2 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Hydrophobin PF01185.18 KIK53788.1 - 8e-13 48.8 3.0 5.8e-12 46.1 1.3 2.7 2 1 0 2 2 2 1 Fungal hydrophobin KleE PF17394.2 KIK53789.1 - 0.07 13.4 3.3 0.15 12.3 3.3 1.6 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein GST_N_2 PF13409.6 KIK53792.1 - 7.8e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK53792.1 - 1.2e-08 35.3 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK53792.1 - 4.8e-07 30.0 0.0 1.1e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK53792.1 - 2.5e-05 24.2 0.0 5.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIK53792.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.6 KIK53792.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CPSF_A PF03178.15 KIK53793.1 - 1.6e-81 274.1 0.0 5.2e-81 272.4 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KIK53793.1 - 7.9e-16 57.7 0.0 1.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF3915 PF13054.6 KIK53793.1 - 4.1 7.4 4.5 13 5.7 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) MORN PF02493.20 KIK53794.1 - 2e-08 33.6 6.7 6.2e-05 22.7 0.3 2.9 2 0 0 2 2 2 2 MORN repeat AIG1 PF04548.16 KIK53796.1 - 3.5e-10 39.6 0.2 1.5e-09 37.5 0.1 2.0 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KIK53796.1 - 1e-06 28.8 0.6 2.5e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK53796.1 - 0.0012 18.8 0.0 0.0041 17.0 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KIK53796.1 - 0.0016 18.0 0.2 0.018 14.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIK53796.1 - 0.033 14.4 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain T_hemolysin PF12261.8 KIK53796.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin AAA_16 PF13191.6 KIK53796.1 - 0.053 13.9 0.0 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KIK53796.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KIK53796.1 - 0.073 13.3 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KIK53796.1 - 0.09 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4635 PF15466.6 KIK53796.1 - 0.099 12.2 2.4 0.086 12.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) DUF3482 PF11981.8 KIK53796.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3482) ABC_tran PF00005.27 KIK53796.1 - 0.16 12.5 2.4 0.52 10.8 0.1 2.5 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 KIK53796.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.8 3 3 1 5 5 5 0 Dynamin family CEP209_CC5 PF16574.5 KIK53796.1 - 5.2 7.2 12.0 0.052 13.7 2.6 2.5 3 0 0 3 3 3 0 Coiled-coil region of centrosome protein CE290 ABC_tran_CTD PF16326.5 KIK53796.1 - 9.4 6.6 20.2 2.9 8.2 1.9 4.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain MORN PF02493.20 KIK53797.1 - 2.9e-10 39.4 5.7 2.8e-05 23.7 0.3 3.6 3 0 0 3 3 3 2 MORN repeat MACPF PF01823.19 KIK53797.1 - 0.0084 16.2 1.3 0.024 14.7 1.3 1.7 1 1 0 1 1 1 1 MAC/Perforin domain Glyco_hydro_18 PF00704.28 KIK53798.1 - 7.8e-06 25.8 0.3 1.2e-05 25.3 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 FerA PF08165.11 KIK53800.1 - 0.081 12.9 0.5 0.26 11.3 0.5 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain DDE_Tnp_4 PF13359.6 KIK53801.1 - 2.8e-18 66.1 0.0 4.3e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_18 PF00704.28 KIK53802.1 - 1e-13 51.7 2.0 1.6e-13 51.1 1.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Nrap_D6 PF17407.2 KIK53802.1 - 0.15 12.3 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Nrap protein domain 6 Herpes_IE68 PF02479.16 KIK53806.1 - 0.066 12.8 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein KDZ PF18758.1 KIK53809.1 - 5.1e-05 23.0 1.0 5.3e-05 22.9 1.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF3663 PF12404.8 KIK53809.1 - 0.084 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase zf-LITAF-like PF10601.9 KIK53809.1 - 1.4 9.3 7.3 1.6 9.1 0.1 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Dimer_Tnp_hAT PF05699.14 KIK53810.1 - 1.1e-12 47.5 0.0 1.2e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2201_N PF13203.6 KIK53811.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain AcetylCoA_hyd_C PF13336.6 KIK53812.1 - 6.5e-13 48.9 0.0 3.7e-09 36.7 0.0 2.1 1 1 1 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK53814.1 - 1e-86 282.5 54.5 3.1e-10 40.5 2.1 9.9 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53814.1 - 1.9e-29 101.8 11.8 0.0008 19.7 0.0 7.9 1 1 8 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53814.1 - 4.9e-12 45.8 8.4 0.028 13.7 0.2 5.9 3 2 4 7 7 7 6 WD40-like domain Frtz PF11768.8 KIK53814.1 - 5.1e-09 35.0 1.2 0.92 7.7 0.0 7.1 2 2 5 7 7 7 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK53814.1 - 3.1e-08 33.9 3.7 1.5 9.4 0.0 7.4 8 1 1 9 9 9 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK53814.1 - 3.6e-08 32.3 7.4 0.00093 17.8 0.2 3.6 1 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.6 KIK53814.1 - 6.4e-08 32.5 10.3 0.0014 18.2 3.1 4.3 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 KIK53814.1 - 7.6e-06 25.1 6.8 0.25 10.2 0.0 5.8 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KIK53814.1 - 8.8e-06 24.8 0.1 0.96 8.2 0.0 4.3 2 2 3 5 5 5 2 Methylamine dehydrogenase heavy chain (MADH) Kelch_6 PF13964.6 KIK53814.1 - 1.9e-05 24.8 8.1 1.7 9.0 0.1 5.4 6 0 0 6 6 5 3 Kelch motif POLO_box PF00659.18 KIK53814.1 - 0.017 15.3 1.9 11 6.3 0.0 4.1 6 0 0 6 6 5 0 POLO box duplicated region PD40 PF07676.12 KIK53814.1 - 0.025 14.5 8.5 19 5.3 0.0 6.7 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.12 KIK53814.1 - 0.031 13.7 0.0 8.2 5.8 0.0 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1258) SF3A2 PF16835.5 KIK53814.1 - 0.19 12.1 0.1 75 3.8 0.0 4.6 7 0 0 7 7 7 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) PSI PF01437.25 KIK53814.1 - 1.2 9.7 5.9 1.6 9.4 0.0 3.8 6 0 0 6 6 6 0 Plexin repeat PH_9 PF15410.6 KIK53816.1 - 3.9e-27 95.0 0.0 4.5e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK53816.1 - 0.00013 22.5 0.0 0.00036 21.0 0.0 1.7 1 1 0 1 1 1 1 PH domain DUF4974 PF16344.5 KIK53817.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) CENP-R PF06729.12 KIK53817.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 Kinetochore component, CENP-R WD40 PF00400.32 KIK53818.1 - 9.1e-24 83.3 12.1 2.2e-07 31.5 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53818.1 - 4.4e-08 33.3 0.9 0.0049 17.2 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53818.1 - 0.00032 20.1 1.9 0.22 10.8 0.2 2.1 2 0 0 2 2 2 2 WD40-like domain Me-amine-dh_H PF06433.11 KIK53818.1 - 0.0098 14.8 0.0 0.18 10.6 0.0 2.0 1 1 1 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) PQQ_3 PF13570.6 KIK53818.1 - 0.028 14.9 2.7 2.2 8.9 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF4242 PF14026.6 KIK53818.1 - 0.068 13.4 0.1 1.7 8.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4242) zf-CCHC PF00098.23 KIK53819.1 - 4.9e-05 23.2 3.3 7.8e-05 22.6 3.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KIK53819.1 - 0.024 14.9 0.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 KIK53819.1 - 0.029 14.1 1.4 0.062 13.0 1.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger NPV_P10 PF05531.12 KIK53821.1 - 0.24 11.9 1.4 0.67 10.5 0.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 KIK53821.1 - 0.45 10.9 7.9 6.1 7.3 3.5 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF16 PF01519.16 KIK53821.1 - 0.51 10.8 2.1 1.1 9.8 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Lectin_N PF03954.14 KIK53821.1 - 0.53 10.0 5.3 0.59 9.9 1.6 2.7 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain TMF_DNA_bd PF12329.8 KIK53821.1 - 2.4 8.2 9.7 1.1 9.3 6.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.20 KIK53823.1 - 0.054 13.2 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain Retrotran_gag_2 PF14223.6 KIK53824.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AcetylCoA_hydro PF02550.15 KIK53825.1 - 0.00044 20.3 0.0 0.0005 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIK53826.1 - 0.051 13.5 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK53827.1 - 2.9e-118 382.3 86.9 2.2e-10 40.9 0.4 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53827.1 - 1.4e-26 92.6 28.0 0.006 16.9 0.1 11.9 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53827.1 - 9.8e-19 67.8 19.9 0.0039 16.6 0.1 9.2 2 2 7 10 10 10 8 WD40-like domain Frtz PF11768.8 KIK53827.1 - 9.3e-08 30.8 9.9 0.57 8.4 0.1 7.2 2 2 7 9 9 9 4 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK53827.1 - 2e-06 26.9 4.3 0.21 10.4 0.0 5.6 4 1 2 8 8 8 2 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 KIK53827.1 - 1e-05 26.0 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK53827.1 - 2.4e-05 24.3 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK53827.1 - 0.00017 20.9 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Gmad1 PF10647.9 KIK53827.1 - 0.0034 17.2 17.8 4.8 6.9 0.6 6.1 1 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain NTPase_1 PF03266.15 KIK53827.1 - 0.01 15.8 0.0 0.08 12.9 0.0 2.5 3 0 0 3 3 3 0 NTPase PQQ PF01011.21 KIK53827.1 - 0.013 15.4 0.3 1.3e+02 2.7 0.0 6.2 8 0 0 8 8 8 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK53827.1 - 0.014 14.0 15.0 0.15 10.6 0.4 4.6 2 1 2 5 5 5 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIK53827.1 - 0.018 15.5 10.0 6.4 7.4 0.0 7.6 11 0 0 11 11 9 0 PQQ-like domain RNA_helicase PF00910.22 KIK53827.1 - 0.055 13.8 0.7 1.4 9.4 0.0 3.6 3 1 1 4 4 4 0 RNA helicase AAA PF00004.29 KIK53827.1 - 0.082 13.3 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK53827.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.32 KIK53828.1 - 5.7e-91 296.0 63.9 6.3e-09 36.3 0.0 14.1 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK53828.1 - 7.3e-31 106.3 16.6 0.0029 17.8 0.0 11.3 1 1 11 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK53828.1 - 3.2e-12 46.4 14.4 0.00039 19.8 0.1 6.3 4 2 1 7 7 7 4 WD40-like domain Frtz PF11768.8 KIK53828.1 - 4.5e-10 38.5 3.1 1 7.6 0.0 7.6 3 2 7 10 10 10 5 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK53828.1 - 1.7e-09 37.6 15.6 2.3e-07 30.7 8.1 3.6 1 1 1 3 3 3 3 PQQ-like domain Ge1_WD40 PF16529.5 KIK53828.1 - 2.7e-07 29.9 9.4 0.6 9.0 0.1 7.5 4 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK53828.1 - 1.3e-06 28.5 1.1 0.029 14.3 0.1 4.7 1 1 4 6 6 6 1 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 KIK53828.1 - 2.3e-05 24.4 0.0 0.00019 21.4 0.0 2.2 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK53828.1 - 5.8e-05 22.4 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PD40 PF07676.12 KIK53828.1 - 6.1e-05 22.8 1.7 40 4.3 0.0 6.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK53828.1 - 9.1e-05 22.9 0.0 0.00028 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK53828.1 - 0.0023 17.8 2.1 61 3.8 0.1 6.8 7 0 0 7 7 7 0 PQQ enzyme repeat DUF727 PF05303.12 KIK53828.1 - 0.0041 17.1 1.1 69 3.6 0.0 5.5 3 1 3 6 6 6 0 Protein of unknown function (DUF727) PQQ_3 PF13570.6 KIK53828.1 - 0.018 15.5 10.7 22 5.7 0.0 7.5 9 0 0 9 9 8 0 PQQ-like domain RNA_helicase PF00910.22 KIK53828.1 - 0.028 14.8 0.0 0.35 11.3 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA PF00004.29 KIK53828.1 - 0.032 14.6 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK53828.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Mustang PF15682.5 KIK53829.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Arylsulfotran_2 PF14269.6 KIK53830.1 - 2.4e-55 188.0 1.1 4.1e-55 187.3 1.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK53830.1 - 2e-16 59.9 0.4 4.4e-15 55.5 0.4 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KIK53830.1 - 0.018 14.9 0.0 0.27 11.2 0.1 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat gpUL132 PF11359.8 KIK53831.1 - 0.84 9.1 3.0 0.75 9.3 0.3 2.0 2 0 0 2 2 2 0 Glycoprotein UL132 Sulfotransfer_3 PF13469.6 KIK53832.1 - 0.012 16.0 0.0 0.032 14.6 0.0 1.6 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK53833.1 - 1.6e-05 25.4 0.0 1.8e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family FMO-like PF00743.19 KIK53834.1 - 3.7e-22 78.5 0.0 2.1e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK53834.1 - 1.8e-20 73.4 0.0 1.9e-17 63.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK53834.1 - 2.5e-13 49.9 0.0 3.3e-09 36.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK53834.1 - 1.9e-10 40.4 0.0 8.4e-08 31.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIK53834.1 - 6.7e-07 29.2 0.1 1.2 8.6 0.1 4.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK53834.1 - 1.4e-06 28.7 0.2 0.053 14.1 0.0 3.2 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK53834.1 - 0.00023 21.3 0.1 0.25 11.6 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KIK53834.1 - 0.00056 20.0 0.0 0.13 12.3 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KIK53834.1 - 0.001 19.1 0.4 0.7 9.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KIK53834.1 - 0.0023 17.3 0.3 0.41 9.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KIK53834.1 - 0.0027 17.1 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 KIK53834.1 - 0.0034 16.8 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase TrkA_N PF02254.18 KIK53834.1 - 0.0069 16.6 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.17 KIK53834.1 - 0.0092 15.2 0.0 0.72 9.0 0.0 2.8 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 KIK53834.1 - 0.015 14.0 0.4 1.3 7.6 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KIK53834.1 - 0.032 13.3 0.4 6.3 5.7 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein ApbA PF02558.16 KIK53834.1 - 0.067 12.8 0.1 21 4.7 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KIK53834.1 - 0.071 12.2 0.6 4.4 6.3 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 KIK53834.1 - 0.075 12.1 1.1 11 5.0 0.0 3.2 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KIK53834.1 - 0.095 13.1 0.0 2.8 8.4 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding ThiF PF00899.21 KIK53834.1 - 0.14 11.5 0.5 2.8 7.2 0.1 2.1 2 0 0 2 2 2 0 ThiF family PAW PF04721.17 KIK53835.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Sugar_tr PF00083.24 KIK53836.1 - 8e-76 255.7 19.3 9.6e-76 255.5 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK53836.1 - 1.4e-26 93.3 30.2 4e-19 68.8 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ArAE_1 PF06081.11 KIK53836.1 - 9.1 6.4 10.6 1.3 9.1 5.0 2.4 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 Sugar_tr PF00083.24 KIK53837.1 - 9.9e-72 242.2 21.5 1.3e-71 241.8 21.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK53837.1 - 1.1e-22 80.4 43.4 1.8e-20 73.2 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec62 PF03839.16 KIK53838.1 - 0.48 9.9 2.4 0.8 9.2 2.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 TctB PF07331.11 KIK53838.1 - 1.2 9.4 8.4 12 6.2 8.4 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PGG PF13962.6 KIK53838.1 - 2.2 8.1 8.1 0.28 11.0 3.0 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF4739 PF15893.5 KIK53839.1 - 0.06 12.9 1.0 0.12 11.9 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) FliT PF05400.13 KIK53839.1 - 0.27 12.1 1.2 0.54 11.1 1.2 1.5 1 0 0 1 1 1 0 Flagellar protein FliT DUF3755 PF12579.8 KIK53841.1 - 0.0069 16.0 0.3 0.017 14.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3755) DnaG_DnaB_bind PF08278.11 KIK53841.1 - 0.27 11.8 2.4 0.64 10.6 2.4 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding p450 PF00067.22 KIK53842.1 - 3.9e-53 180.8 0.0 4.9e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribo_biogen_C PF04034.13 KIK53842.1 - 0.00039 20.2 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal Nucleo_P87 PF07267.11 KIK53844.1 - 2.1 7.1 4.3 3.3 6.5 4.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CBM_20 PF00686.19 KIK53845.1 - 5.1e-30 103.2 0.1 1.1e-29 102.2 0.1 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase_C PF02806.18 KIK53845.1 - 9e-13 48.5 0.0 2.5e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KIK53845.1 - 2.4e-12 47.1 0.0 2.1e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 KIK53845.1 - 0.058 13.8 0.0 0.98 9.8 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) FapA PF03961.13 KIK53845.1 - 0.33 9.5 0.5 0.48 9.0 0.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA PF00004.29 KIK53847.1 - 9.1e-13 48.8 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK53847.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK53847.1 - 0.038 14.3 0.3 0.48 10.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK53847.1 - 0.1 13.0 0.1 0.27 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF1145 PF06611.12 KIK53848.1 - 0.032 14.2 0.5 0.094 12.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) p450 PF00067.22 KIK53850.1 - 4.8e-73 246.5 0.0 5.5e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_trans_CmpB PF06541.11 KIK53854.1 - 0.49 10.6 16.1 1.6 9.0 16.1 1.9 1 1 0 1 1 1 0 Putative ABC-transporter type IV IIGP PF05049.13 KIK53855.1 - 9.8e-23 80.8 0.2 5.8e-22 78.3 0.1 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK53855.1 - 8.3e-07 29.1 0.5 2.3e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KIK53855.1 - 0.00018 21.7 0.0 0.00036 20.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK53855.1 - 0.00028 20.8 0.2 0.0033 17.4 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KIK53855.1 - 0.0089 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIK53855.1 - 0.013 14.8 0.0 0.036 13.4 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.18 KIK53855.1 - 0.02 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Bee_toxin PF17454.2 KIK53855.1 - 0.038 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Honey bee toxin Selenoprotein_S PF06936.11 KIK53855.1 - 0.048 13.5 11.9 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) AAA_21 PF13304.6 KIK53855.1 - 0.31 10.8 0.1 0.31 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Raftlin PF15250.6 KIK53855.1 - 0.43 9.3 12.6 0.022 13.5 6.8 1.6 2 0 0 2 2 2 0 Raftlin ABC_tran PF00005.27 KIK53855.1 - 0.56 10.7 12.9 0.17 12.4 4.0 3.2 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 KIK53855.1 - 2 8.7 0.0 2 8.7 0.0 3.1 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KIK53855.1 - 2.1 8.1 7.7 3.1 7.5 0.3 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Nup88 PF10168.9 KIK53855.1 - 2.3 5.9 15.8 3.2 5.4 15.8 1.1 1 0 0 1 1 1 0 Nuclear pore component tRNA-synt_His PF13393.6 KIK53855.1 - 3.6 6.8 10.4 6 6.0 10.4 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase AAA_16 PF13191.6 KIK53855.1 - 5.7 7.3 10.9 0.61 10.5 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain Prominin PF05478.11 KIK53855.1 - 6.8 4.5 5.1 9.8 4.0 5.1 1.2 1 0 0 1 1 1 0 Prominin UbiA PF01040.18 KIK53856.1 - 7.3e-32 110.6 15.5 9.3e-32 110.3 15.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF745 PF05335.13 KIK53857.1 - 0.012 15.4 30.3 0.049 13.4 5.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Period_C PF12114.8 KIK53857.1 - 0.016 14.8 4.2 0.043 13.4 4.2 1.8 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CENP-F_leu_zip PF10473.9 KIK53857.1 - 0.15 12.0 46.2 0.046 13.7 28.3 3.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_F12L PF03337.13 KIK53857.1 - 0.4 8.8 3.6 0.26 9.4 0.1 1.9 2 0 0 2 2 2 0 Poxvirus F12L protein Med3 PF11593.8 KIK53857.1 - 0.66 9.1 7.5 0.63 9.2 5.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Cas_DxTHG PF09455.10 KIK53857.1 - 1.4 8.5 7.5 1.7 8.1 7.5 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family ATG16 PF08614.11 KIK53857.1 - 1.6 8.9 53.3 0.059 13.6 11.6 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KIK53857.1 - 1.7 7.5 30.0 2.2 7.1 30.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CFEM PF05730.11 KIK53858.1 - 1.1e-11 44.7 13.5 1.3e-11 44.4 13.5 1.1 1 0 0 1 1 1 1 CFEM domain Fungal_lectin PF07938.12 KIK53861.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal fucose-specific lectin Fungal_lectin PF07938.12 KIK53863.1 - 0.0042 16.5 0.0 0.0058 16.1 0.0 1.3 1 1 0 1 1 1 1 Fungal fucose-specific lectin UDPGT PF00201.18 KIK53865.1 - 9.5e-11 41.2 0.0 1.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK53865.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain IIGP PF05049.13 KIK53866.1 - 4.8e-19 68.7 1.0 1.2e-18 67.4 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK53866.1 - 1e-06 28.8 1.0 5.8e-06 26.4 0.0 2.9 2 1 1 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK53866.1 - 0.0035 17.3 1.8 0.0095 15.9 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KIK53866.1 - 0.02 15.4 0.2 0.02 15.4 0.2 4.3 2 2 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 KIK53866.1 - 0.078 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KIK53866.1 - 0.13 12.3 0.1 0.13 12.3 0.1 5.1 2 1 0 3 3 3 0 Dynamin family AAA_16 PF13191.6 KIK53866.1 - 0.44 10.9 0.0 0.44 10.9 0.0 4.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KIK53866.1 - 0.57 10.7 0.0 0.57 10.7 0.0 5.4 2 1 2 4 4 4 0 AAA domain Glyco_hydro_28 PF00295.17 KIK53868.1 - 6.4e-47 160.2 0.9 8.3e-47 159.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KIK53868.1 - 3.7e-07 30.2 8.8 9.2e-06 25.6 5.4 3.4 1 1 1 2 2 2 2 Pectate lyase superfamily protein Podoplanin PF05808.11 KIK53869.1 - 0.0017 18.5 7.2 0.0017 18.5 7.2 1.7 2 0 0 2 2 2 1 Podoplanin Glycophorin_A PF01102.18 KIK53869.1 - 0.0054 17.0 1.4 0.0092 16.2 0.6 1.8 1 1 0 1 1 1 1 Glycophorin A Amnionless PF14828.6 KIK53869.1 - 0.044 12.6 0.1 0.064 12.1 0.1 1.2 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 KIK53869.1 - 0.053 13.1 0.2 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 CD34/Podocalyxin family SKG6 PF08693.10 KIK53869.1 - 0.07 12.5 0.1 0.07 12.5 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PhoR PF11808.8 KIK53869.1 - 0.1 13.0 0.7 0.22 11.9 0.7 1.5 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR CcmD PF04995.14 KIK53869.1 - 0.79 9.9 5.8 1.6 8.9 5.8 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TMEM154 PF15102.6 KIK53869.1 - 0.86 9.5 10.6 0.056 13.3 3.4 2.5 2 1 0 2 2 2 0 TMEM154 protein family Fungal_trans PF04082.18 KIK53870.1 - 4.3e-17 62.0 0.7 4.3e-17 62.0 0.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK53870.1 - 4.1e-05 23.6 9.2 7.1e-05 22.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KIK53870.1 - 0.079 11.4 0.0 0.18 10.2 0.0 1.5 2 0 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B AA_permease PF00324.21 KIK53872.1 - 4.7e-114 381.6 41.0 5.6e-114 381.4 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK53872.1 - 2.1e-31 109.2 42.4 2.5e-31 108.9 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF202 PF02656.15 KIK53877.1 - 0.027 14.9 0.1 0.06 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF202) RIFIN PF02009.16 KIK53877.1 - 0.035 14.0 0.2 0.11 12.4 0.2 1.8 1 1 0 1 1 1 0 Rifin Amnionless PF14828.6 KIK53877.1 - 0.039 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Amnionless HIG_1_N PF04588.13 KIK53877.1 - 0.094 12.9 0.5 0.18 12.0 0.5 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region T4SS_CagC PF16943.5 KIK53877.1 - 0.099 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF2207 PF09972.9 KIK53877.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 KIK53877.1 - 0.25 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 KIK53877.1 - 0.3 11.0 0.9 0.48 10.4 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain BA14K PF07886.11 KIK53878.1 - 0.36 10.7 2.1 0.54 10.2 2.1 1.2 1 0 0 1 1 1 0 BA14K-like protein Podoplanin PF05808.11 KIK53880.1 - 0.017 15.2 0.9 0.031 14.4 0.9 1.4 1 0 0 1 1 1 0 Podoplanin Rab_bind PF16704.5 KIK53880.1 - 0.12 12.5 0.2 0.39 10.8 0.2 1.9 1 0 0 1 1 1 0 Rab binding domain BatA PF07584.11 KIK53881.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Herpes_gE PF02480.16 KIK53881.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SOG2 PF10428.9 KIK53881.1 - 0.57 9.3 12.5 0.91 8.7 12.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Rax2 PF12768.7 KIK53882.1 - 0.005 16.3 0.2 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 Cortical protein marker for cell polarity DUF2207 PF09972.9 KIK53882.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM51 PF15345.6 KIK53883.1 - 0.005 16.7 1.2 0.014 15.2 0.1 2.0 1 1 1 2 2 2 1 Transmembrane protein 51 Coatomer_g_Cpla PF16381.5 KIK53883.1 - 0.17 12.1 0.2 0.28 11.4 0.2 1.3 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Herpes_gE PF02480.16 KIK53883.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RPAP1_N PF08621.10 KIK53884.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal Myc_target_1 PF15179.6 KIK53885.1 - 0.016 15.1 0.4 0.019 14.9 0.4 1.3 1 1 0 1 1 1 0 Myc target protein 1 Amnionless PF14828.6 KIK53885.1 - 0.07 11.9 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Nitrate_red_gam PF02665.14 KIK53885.1 - 0.22 11.0 0.1 0.28 10.7 0.1 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF1180 PF06679.12 KIK53886.1 - 8.2e-05 23.1 2.3 8.2e-05 23.1 2.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) TMEM154 PF15102.6 KIK53886.1 - 0.0017 18.3 0.2 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family PIRT PF15099.6 KIK53886.1 - 0.012 15.2 0.3 0.029 13.9 0.3 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Macoilin PF09726.9 KIK53886.1 - 0.048 12.2 0.0 0.1 11.1 0.0 1.5 1 1 0 1 1 1 0 Macoilin family Herpes_gE PF02480.16 KIK53886.1 - 0.062 12.0 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 KIK53887.1 - 0.02 14.3 0.5 0.041 13.3 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KIK53887.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Tmemb_cc2 PF10267.9 KIK53887.1 - 0.83 8.7 3.2 0.53 9.4 0.5 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CcmD PF04995.14 KIK53887.1 - 7.8 6.7 8.5 0.5 10.5 2.4 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) CcmD PF04995.14 KIK53889.1 - 0.042 13.9 4.8 0.11 12.6 4.8 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2062 PF09835.9 KIK53889.1 - 0.089 12.7 0.6 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) EphA2_TM PF14575.6 KIK53889.1 - 0.11 13.3 0.0 0.27 12.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KIK53889.1 - 4.3 7.2 5.9 48 3.8 5.9 2.5 1 1 0 1 1 1 0 TMEM154 protein family 4HBT_2 PF13279.6 KIK53890.1 - 8.8e-08 32.7 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4939 PF16297.5 KIK53892.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Glyco_hydro_18 PF00704.28 KIK53897.1 - 5.4e-15 55.9 2.8 1e-14 55.0 2.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_10 PF13460.6 KIK53898.1 - 9.9e-26 90.8 0.1 1.5e-25 90.1 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK53898.1 - 0.00063 19.4 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIK53898.1 - 0.0013 18.2 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glft2_N PF17994.1 KIK53898.1 - 0.037 14.0 0.2 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Galactofuranosyltransferase 2 N-terminal Semialdhyde_dh PF01118.24 KIK53898.1 - 0.096 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CNH PF00780.22 KIK53901.1 - 7.3e-60 202.9 0.0 9.1e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 CNH domain HMMR_N PF15905.5 KIK53903.1 - 0.0038 16.8 13.5 0.0038 16.8 13.5 2.2 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal HNOBA PF07701.14 KIK53903.1 - 0.0061 16.0 0.1 0.0061 16.0 0.1 1.9 3 0 0 3 3 3 1 Heme NO binding associated SPATA24 PF15175.6 KIK53903.1 - 0.074 12.9 14.8 0.054 13.4 12.1 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 DASH_Spc34 PF08657.10 KIK53903.1 - 0.095 12.5 8.9 0.016 15.0 5.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF4407 PF14362.6 KIK53903.1 - 0.14 11.5 7.0 0.28 10.5 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KIK53903.1 - 0.25 11.7 23.4 0.32 11.4 17.9 2.8 1 1 2 3 3 3 0 Fez1 APG6_N PF17675.1 KIK53903.1 - 0.5 10.9 37.1 0.035 14.6 12.1 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region Lebercilin PF15619.6 KIK53903.1 - 1.5 8.5 27.5 2.7 7.6 0.9 2.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF327 PF03885.13 KIK53903.1 - 2.5 8.1 10.1 1.5 8.8 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF327) Csm1_N PF18504.1 KIK53903.1 - 2.6 8.5 18.4 0.48 10.8 3.3 3.7 3 1 1 4 4 4 0 Csm1 N-terminal domain UPF0242 PF06785.11 KIK53903.1 - 4.8 7.2 28.9 1.2 9.2 14.6 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KIK53903.1 - 5.5 6.3 11.7 0.44 9.9 6.4 1.8 2 0 0 2 2 2 0 FAM76 protein Lectin_N PF03954.14 KIK53903.1 - 5.6 6.7 12.8 0.86 9.3 2.4 2.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain YscO-like PF16789.5 KIK53903.1 - 5.8 6.9 17.4 0.58 10.2 9.4 2.3 2 0 0 2 2 2 0 YscO-like protein Alpha_kinase PF02816.18 KIK53905.1 - 2.6e-23 83.1 0.4 4.7e-23 82.3 0.4 1.4 1 0 0 1 1 1 1 Alpha-kinase family Glyco_hydro_18 PF00704.28 KIK53910.1 - 2e-14 54.1 1.6 3.1e-14 53.4 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PTP_tm PF18861.1 KIK53911.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Promethin PF16015.5 KIK53913.1 - 0.059 13.3 3.5 0.043 13.7 2.3 1.5 1 1 0 1 1 1 0 Promethin FAD_binding_3 PF01494.19 KIK53914.1 - 1e-68 232.1 0.0 1.5e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK53914.1 - 0.00062 19.1 0.1 0.0019 17.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK53914.1 - 0.00062 19.1 0.6 0.016 14.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK53914.1 - 0.00069 19.3 0.3 0.0023 17.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK53914.1 - 0.00081 18.2 0.1 0.018 13.7 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KIK53914.1 - 0.0023 18.5 0.2 0.81 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK53914.1 - 0.0029 17.8 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK53914.1 - 0.0049 16.0 0.2 0.022 13.9 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK53914.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK53914.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Peripla_BP_6 PF13458.6 KIK53915.1 - 0.034 13.8 0.2 0.045 13.4 0.2 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF2235 PF09994.9 KIK53916.1 - 2.9e-65 220.5 0.0 3.6e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pox_F16 PF04708.12 KIK53917.1 - 0.04 13.4 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F16 protein DUF3810 PF12725.7 KIK53917.1 - 0.22 10.8 0.6 0.22 10.8 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PaO PF08417.12 KIK53920.1 - 0.056 13.6 0.2 0.061 13.5 0.2 1.2 1 0 0 1 1 1 0 Pheophorbide a oxygenase CAAD PF14159.6 KIK53925.1 - 0.11 12.3 0.7 1.4 8.8 0.1 2.9 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4633 PF15464.6 KIK53929.1 - 0.14 12.3 1.0 0.2 11.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) TssN PF17555.2 KIK53933.1 - 1.3 8.4 5.7 1 8.7 1.8 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Spc7 PF08317.11 KIK53936.1 - 0.016 14.1 2.4 0.022 13.6 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 KIK53936.1 - 0.019 14.7 0.9 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Amidinotransf PF02274.17 KIK53936.1 - 0.1 11.7 0.6 0.16 11.0 0.6 1.3 1 0 0 1 1 1 0 Amidinotransferase DUF4618 PF15397.6 KIK53936.1 - 0.22 10.9 7.4 0.022 14.2 2.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PKcGMP_CC PF16808.5 KIK53936.1 - 0.88 9.5 5.4 9.2 6.2 0.5 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 KIK53937.1 - 0.0088 16.2 0.4 0.017 15.3 0.4 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KIK53937.1 - 0.011 15.2 1.1 0.017 14.6 1.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 KIK53937.1 - 0.041 12.8 2.0 0.063 12.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KIK53937.1 - 0.057 14.0 5.5 0.11 13.0 5.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 KIK53937.1 - 0.06 13.6 2.4 0.098 12.9 2.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 KIK53937.1 - 0.086 12.9 1.6 0.15 12.0 1.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CtIP_N PF10482.9 KIK53937.1 - 0.086 12.9 1.9 0.19 11.8 1.9 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Csm1_N PF18504.1 KIK53937.1 - 0.097 13.0 5.6 0.23 11.8 3.6 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain ADIP PF11559.8 KIK53937.1 - 0.1 12.7 1.7 0.2 11.7 1.3 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_23 PF13476.6 KIK53937.1 - 0.25 11.8 1.5 0.38 11.2 1.5 1.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 KIK53937.1 - 0.26 11.3 10.1 0.046 13.7 5.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KIK53937.1 - 0.64 8.8 5.1 0.97 8.2 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3810 PF12725.7 KIK53939.1 - 0.015 14.7 1.9 0.015 14.6 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) RE_HindIII PF09518.10 KIK53940.1 - 0.079 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease KH_1 PF00013.29 KIK53941.1 - 0.056 13.3 0.1 12 5.8 0.0 2.7 2 1 0 2 2 2 0 KH domain KH_1 PF00013.29 KIK53943.1 - 1.6e-09 37.4 0.2 5.9e-07 29.2 0.1 2.4 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 KIK53943.1 - 0.097 12.8 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Trp repressor protein CNH PF00780.22 KIK53944.1 - 3.8e-59 200.6 0.0 6.5e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KIK53944.1 - 2.3e-55 187.6 0.2 4.4e-33 115.0 0.0 4.3 4 0 0 4 4 4 4 RhoGEF domain PH_5 PF15405.6 KIK53944.1 - 8.8e-16 58.2 0.0 3.3e-15 56.4 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIK53944.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KIK53944.1 - 0.014 15.9 0.0 0.11 13.0 0.0 2.3 1 1 0 1 1 1 0 PH domain Integrase_H2C2 PF17921.1 KIK53945.1 - 2.9e-13 49.7 2.3 1.3e-12 47.6 0.2 2.9 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KIK53945.1 - 2.8e-07 30.5 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK53945.1 - 6.4e-05 23.2 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MerC PF03203.14 KIK53947.1 - 0.048 14.1 3.1 0.073 13.5 1.9 1.8 1 1 1 2 2 2 0 MerC mercury resistance protein Hum_adeno_E3A PF05393.11 KIK53947.1 - 0.47 10.5 4.8 1.1 9.3 0.5 2.4 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein Got1 PF04178.12 KIK53947.1 - 0.88 10.0 8.1 0.47 10.9 5.3 2.0 2 0 0 2 2 2 0 Got1/Sft2-like family DUF4491 PF14898.6 KIK53947.1 - 2.1 8.8 9.2 0.69 10.4 2.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) CRPA PF05745.11 KIK53948.1 - 0.17 11.9 0.3 0.19 11.7 0.3 1.1 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) RE_HindIII PF09518.10 KIK53949.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease DDE_1 PF03184.19 KIK53950.1 - 3.4e-07 30.1 0.1 6.8e-06 25.8 0.0 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease Sugar_tr PF00083.24 KIK53951.1 - 4.5e-105 352.1 15.8 5.4e-105 351.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK53951.1 - 1.8e-22 79.7 29.0 1.8e-22 79.7 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KIK53951.1 - 0.0049 15.9 2.7 0.011 14.8 2.1 2.0 1 1 0 1 1 1 1 PUCC protein Acyl-CoA_dh_M PF02770.19 KIK53952.1 - 0.024 14.8 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Cu-oxidase PF00394.22 KIK53953.1 - 7.1e-38 130.2 0.6 2.2e-36 125.4 0.2 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK53953.1 - 4.7e-33 113.8 0.9 2.1e-31 108.5 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK53953.1 - 1.7e-30 105.5 2.9 4.9e-29 100.7 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase FAD_binding_2 PF00890.24 KIK53954.1 - 2e-120 402.7 2.6 2.7e-120 402.3 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIK53954.1 - 6.9e-41 139.2 0.2 1e-40 138.7 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KIK53954.1 - 0.0027 17.0 1.1 0.77 8.9 0.4 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK53954.1 - 0.008 15.3 0.7 3.5 6.6 1.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KIK53954.1 - 0.04 13.2 0.4 3.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Thi4 family Cu-oxidase PF00394.22 KIK53955.1 - 6.2e-38 130.4 1.7 2.7e-37 128.3 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK53955.1 - 2.3e-31 108.4 0.8 1.1e-29 102.9 0.2 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK53955.1 - 1.3e-26 92.9 3.4 4.6e-26 91.2 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase CBM_6 PF03422.15 KIK53955.1 - 0.026 14.8 0.7 0.62 10.4 0.2 2.5 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) G-alpha PF00503.20 KIK53956.1 - 7.8e-71 239.1 0.2 9.5e-71 238.8 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.20 KIK53957.1 - 1.4e-75 254.7 0.6 2e-75 254.2 0.6 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK53957.1 - 1.5e-05 24.5 0.2 0.00053 19.5 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Qn_am_d_aIII PF09099.10 KIK53957.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III zf-C2H2 PF00096.26 KIK53958.1 - 0.031 14.8 8.9 2.1 9.0 1.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 KIK53958.1 - 2.6 6.0 3.9 1.2e+02 0.5 7.3 1.7 2 0 0 2 2 2 0 DNA polymerase phi zf-C2H2_4 PF13894.6 KIK53958.1 - 2.8 9.0 7.9 2.3 9.3 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 KIK53959.1 - 7.8e-27 94.1 46.7 1.2e-24 86.9 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK53960.1 - 8.2e-25 87.5 50.5 1.9e-22 79.7 37.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 KIK53961.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK53961.1 - 0.00029 21.1 0.0 0.00038 20.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK53961.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK53961.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein HRG PF16954.5 KIK53962.1 - 0.08 13.4 6.8 1.3 9.5 0.0 3.6 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2157 PF09925.9 KIK53962.1 - 3.6 7.4 12.8 0.23 11.2 2.3 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) BaxI_1 PF12811.7 KIK53962.1 - 8 5.9 8.2 4.4 6.8 4.2 2.4 2 0 0 2 2 2 0 Bax inhibitor 1 like HRG PF16954.5 KIK53964.1 - 0.38 11.2 5.8 1.1 9.7 0.1 3.7 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF4231 PF14015.6 KIK53964.1 - 0.91 10.0 7.1 1.9 9.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Cation_ATPase_C PF00689.21 KIK53965.1 - 1.2 8.9 11.3 0.066 12.9 4.8 2.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus HRG PF16954.5 KIK53965.1 - 8.1 6.9 13.0 8.2 6.9 0.8 4.0 3 1 1 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF4231 PF14015.6 KIK53966.1 - 1.7 9.1 5.3 11 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) GMC_oxred_C PF05199.13 KIK53969.1 - 0.0021 18.6 0.0 0.012 16.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase zf-H2C2_2 PF13465.6 KIK53971.1 - 0.0024 18.2 0.1 0.0024 18.2 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK53971.1 - 0.011 16.2 4.0 0.058 13.9 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK53971.1 - 0.052 14.4 4.6 2.1 9.4 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger AA_permease PF00324.21 KIK53973.1 - 1.2e-101 340.7 34.0 1.3e-101 340.6 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK53973.1 - 1.6e-21 76.6 37.0 2e-21 76.3 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.12 KIK53973.1 - 0.12 12.4 0.3 0.12 12.4 0.3 4.1 3 1 0 3 3 3 0 Protein of unknown function, DUF485 Sugar_tr PF00083.24 KIK53974.1 - 4.5e-81 273.0 12.8 5.2e-81 272.8 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK53974.1 - 7.4e-17 61.3 13.5 7.4e-17 61.3 13.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 KIK53975.1 - 2.3e-38 130.1 8.5 2.4e-14 53.2 0.6 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK53975.1 - 1e-27 96.1 1.1 1.5e-13 50.8 0.3 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KIK53975.1 - 0.00022 21.4 0.1 2.5 8.3 0.0 3.2 3 0 0 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 KIK53975.1 - 0.00028 20.7 0.2 0.16 11.9 0.0 3.1 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 KIK53975.1 - 0.00045 20.2 0.0 7.3 6.6 0.0 3.1 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 KIK53975.1 - 0.0035 17.5 1.6 0.15 12.3 0.0 2.9 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KIK53975.1 - 0.011 15.9 2.4 3.7 7.7 0.0 2.9 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KIK53975.1 - 0.018 15.4 1.7 6.5 7.2 0.0 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GST_N_3 PF13417.6 KIK53976.1 - 5e-19 68.5 0.0 8.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK53976.1 - 5.6e-19 68.3 0.0 1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK53976.1 - 1.6e-11 44.3 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK53976.1 - 2.4e-11 43.7 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK53976.1 - 0.00016 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK53976.1 - 0.0019 18.4 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK53976.1 - 0.015 16.0 0.0 0.46 11.3 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N_5 PF18485.1 KIK53976.1 - 0.065 13.6 0.1 10 6.6 0.0 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Tcell_CD4_C PF12104.8 KIK53977.1 - 0.067 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region NmrA PF05368.13 KIK53978.1 - 3.7e-21 75.7 0.0 4.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK53978.1 - 4.6e-09 36.4 0.0 6.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK53978.1 - 0.0061 16.0 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK53978.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KIK53978.1 - 0.38 10.1 0.9 1.5 8.1 0.6 1.9 2 0 0 2 2 2 0 ThiF family FA_hydroxylase PF04116.13 KIK53980.1 - 1.6e-22 80.2 20.9 1.6e-22 80.2 20.9 2.6 2 1 1 3 3 3 3 Fatty acid hydroxylase superfamily IDO PF01231.18 KIK53981.1 - 3.7e-117 391.7 0.0 4.3e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase E1-E2_ATPase PF00122.20 KIK53982.1 - 8.1e-41 139.5 0.2 8.1e-41 139.5 0.2 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK53982.1 - 1.1e-17 65.1 0.1 1.9e-17 64.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK53982.1 - 2.4e-12 46.4 0.0 5.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus YrvL PF14184.6 KIK53982.1 - 0.0013 18.9 6.5 0.0013 18.9 6.5 2.1 2 0 0 2 2 2 1 Regulatory protein YrvL Hydrolase_3 PF08282.12 KIK53982.1 - 0.0027 17.5 1.6 0.0057 16.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK53982.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF1218 PF06749.12 KIK53983.1 - 0.019 15.5 5.6 0.019 15.5 5.6 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) Glyco_hydro_61 PF03443.14 KIK53985.1 - 5.8e-38 130.9 0.1 1e-37 130.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GREB1 PF15782.5 KIK53985.1 - 0.89 6.6 11.6 1.1 6.2 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 KIK53985.1 - 8.5 6.2 18.6 12 5.7 18.6 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KIK53985.1 - 9.6 4.9 20.0 13 4.4 20.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5127 PF17168.4 KIK53986.1 - 1.5e-65 221.2 3.2 1.5e-65 221.2 3.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK53986.1 - 1.2e-43 148.7 0.0 2.4e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK53986.1 - 1.6e-25 90.5 0.9 4.6e-25 89.0 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK53986.1 - 4.7e-05 22.8 0.6 0.00013 21.4 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK53986.1 - 0.0016 17.8 0.1 0.0049 16.2 0.1 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Pkinase PF00069.25 KIK53987.1 - 1.4e-41 142.7 0.1 5.8e-31 107.8 0.0 4.3 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK53987.1 - 3.3e-23 82.3 0.1 2.6e-19 69.5 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK53987.1 - 1.6e-05 23.9 0.0 1.6e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase YL1 PF05764.13 KIK53987.1 - 0.00047 20.3 4.2 0.00047 20.3 4.2 2.5 2 0 0 2 2 2 1 YL1 nuclear protein APH PF01636.23 KIK53987.1 - 0.0031 17.5 0.0 0.0031 17.5 0.0 3.2 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK53987.1 - 0.12 11.6 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Nop14 PF04147.12 KIK53987.1 - 1.6 6.9 41.8 2.2 6.4 41.8 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 KIK53987.1 - 6.8 7.0 35.8 7.9 6.8 19.5 2.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 KIK53987.1 - 9.1 4.4 42.1 0.58 8.4 16.1 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF5127 PF17168.4 KIK53990.1 - 4.1e-62 209.9 5.3 9.4e-62 208.8 5.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK53990.1 - 5.2e-42 143.4 0.0 1.5e-41 141.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK53990.1 - 5.8e-39 134.2 0.5 2.7e-38 132.0 0.2 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK53990.1 - 2e-05 24.0 0.3 6.2e-05 22.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK53990.1 - 0.001 18.4 0.1 0.0031 16.8 0.1 1.8 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_61 PF03443.14 KIK53991.1 - 4e-33 115.1 0.1 7.1e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GREB1 PF15782.5 KIK53991.1 - 0.21 8.7 12.7 0.28 8.3 12.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SYF2 PF08231.12 KIK53993.1 - 0.015 15.7 0.1 0.018 15.5 0.1 1.1 1 0 0 1 1 1 0 SYF2 splicing factor RT_RNaseH PF17917.1 KIK53994.1 - 1.3e-23 83.2 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KIK53994.1 - 3.9e-17 62.5 0.0 6.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KIK53994.1 - 6.9e-16 58.1 0.0 1.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NitrOD5 PF11537.8 KIK53994.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 DUF5127 PF17168.4 KIK53996.1 - 4.6e-67 226.1 0.4 1.1e-66 224.8 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK53996.1 - 5.5e-46 156.4 1.4 1e-44 152.3 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK53996.1 - 4.6e-40 137.8 0.1 1.1e-39 136.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KIK53996.1 - 8.3e-05 22.0 0.0 0.00083 18.7 0.1 2.3 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KIK53996.1 - 0.0085 15.6 2.4 0.025 14.1 1.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4964) Glyco_hydro_61 PF03443.14 KIK53997.1 - 7e-38 130.6 0.1 1.2e-37 129.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Apt1 PF10351.9 KIK53997.1 - 3.6 6.3 22.4 5.4 5.8 22.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF334 PF03904.13 KIK53999.1 - 0.02 14.5 2.0 0.032 13.8 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF687 PF05095.12 KIK53999.1 - 0.24 9.8 7.5 0.32 9.5 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) RVT_2 PF07727.14 KIK54000.1 - 5.1e-37 127.8 0.0 8.9e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KIK54000.1 - 2.6e-10 40.1 0.0 6.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KIK54000.1 - 2.6e-08 34.1 0.0 6.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain p450 PF00067.22 KIK54001.1 - 7.9e-57 193.0 0.0 2.4e-55 188.1 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54002.1 - 1.6e-83 281.0 0.0 2.1e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NMO PF03060.15 KIK54002.1 - 1.4e-36 126.6 4.3 6.2e-35 121.2 4.3 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK54002.1 - 2.8e-12 46.3 0.1 5.2e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK54002.1 - 1e-06 28.0 5.4 1e-06 28.0 5.4 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Trp_syntA PF00290.20 KIK54002.1 - 0.019 13.8 0.3 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Tryptophan synthase alpha chain CitMHS PF03600.16 KIK54002.1 - 0.022 14.0 0.0 0.046 12.9 0.0 1.6 1 1 0 1 1 1 0 Citrate transporter Glu_synthase PF01645.17 KIK54002.1 - 0.038 13.1 3.5 0.13 11.4 3.5 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.14 KIK54002.1 - 0.059 12.5 0.8 0.18 11.0 0.8 1.8 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KIK54002.1 - 0.075 12.5 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 KIK54002.1 - 0.14 11.5 1.3 0.28 10.5 1.3 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF4094 PF13334.6 KIK54003.1 - 1.9 9.0 4.3 9.6 6.7 4.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Ribosomal_L37 PF08561.10 KIK54004.1 - 0.73 10.4 12.9 0.87 10.1 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Cu-oxidase PF00394.22 KIK54007.1 - 2.4e-38 131.7 0.1 1.4e-37 129.3 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK54007.1 - 6.2e-33 113.3 0.1 1.6e-31 108.8 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK54007.1 - 2.6e-26 92.0 1.2 7.7e-24 84.0 0.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KIK54008.1 - 1.4e-40 139.0 0.1 5.4e-39 133.9 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK54008.1 - 4.7e-33 113.7 0.1 2e-31 108.5 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK54008.1 - 1.9e-30 105.4 1.5 4.2e-28 97.8 0.0 3.4 3 1 0 3 3 3 1 Multicopper oxidase Hjc PF01870.18 KIK54008.1 - 0.048 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF3938 PF13074.6 KIK54010.1 - 0.18 12.1 3.8 0.13 12.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Diphtheria_C PF02763.14 KIK54011.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Diphtheria toxin, C domain GalKase_gal_bdg PF10509.9 KIK54012.1 - 4.9e-23 80.4 0.8 8.2e-23 79.7 0.0 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KIK54012.1 - 3.4e-15 56.2 0.0 1.1e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KIK54012.1 - 3.6e-13 49.5 1.6 1.1e-12 48.0 1.6 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cu-oxidase_2 PF07731.14 KIK54015.1 - 1.7e-37 128.2 2.4 4.2e-35 120.5 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK54015.1 - 3.3e-37 127.1 0.5 6.4e-36 123.0 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KIK54015.1 - 3.1e-34 118.4 0.1 1.3e-16 61.1 0.1 3.7 4 0 0 4 4 4 2 Multicopper oxidase Dimer_Tnp_hAT PF05699.14 KIK54017.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF4729 PF15866.5 KIK54017.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) NmrA PF05368.13 KIK54019.1 - 7.4e-20 71.5 0.0 9.8e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK54019.1 - 1.2e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK54019.1 - 2.9e-05 24.3 0.0 4.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIK54019.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KIK54019.1 - 0.0032 17.7 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 KIK54019.1 - 0.0061 17.0 0.0 0.0098 16.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK54019.1 - 0.0063 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIK54019.1 - 0.013 16.1 0.0 0.025 15.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KIK54019.1 - 0.03 15.1 0.0 0.044 14.6 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DAO PF01266.24 KIK54019.1 - 0.051 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KIK54019.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KIK54019.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3237 PF11578.8 KIK54020.1 - 0.0026 17.6 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF5426 PF17473.2 KIK54021.1 - 1.9 8.7 6.3 0.13 12.5 0.7 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF5426) NmrA PF05368.13 KIK54024.1 - 3.2e-18 66.1 0.0 5.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK54024.1 - 7.5e-08 32.5 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK54024.1 - 1.2e-07 32.1 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIK54024.1 - 6.7e-06 25.7 0.0 9.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIK54024.1 - 0.00036 20.9 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK54024.1 - 0.00074 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KIK54024.1 - 0.00088 19.8 0.0 0.0029 18.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 KIK54024.1 - 0.00093 20.0 0.0 0.0019 19.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DAO PF01266.24 KIK54024.1 - 0.0021 17.7 0.1 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 KIK54024.1 - 0.0021 18.6 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KIK54024.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 KIK54024.1 - 0.056 13.4 0.0 0.26 11.3 0.0 2.0 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.19 KIK54024.1 - 0.062 12.3 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.14 KIK54024.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIK54024.1 - 0.096 12.3 0.2 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDP_Man_Dehyd PF16363.5 KIK54024.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KIK54024.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 KIK54025.1 - 2.5e-18 66.5 0.0 3.2e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK54025.1 - 1.9e-08 34.4 0.0 2.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KIK54025.1 - 5.4e-05 23.3 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KIK54025.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK54025.1 - 0.00085 19.6 0.1 0.0014 18.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KIK54025.1 - 0.026 14.1 0.4 0.043 13.4 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK54025.1 - 0.062 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.15 KIK54025.1 - 0.12 13.2 0.1 0.21 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NmrA PF05368.13 KIK54026.1 - 0.00012 21.7 0.0 0.00044 19.9 0.1 1.6 1 1 1 2 2 2 1 NmrA-like family GCV_H PF01597.19 KIK54026.1 - 0.1 12.5 0.0 0.29 11.0 0.1 1.7 1 1 0 1 1 1 0 Glycine cleavage H-protein NmrA PF05368.13 KIK54027.1 - 8.3e-14 51.7 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK54027.1 - 2.5e-06 27.5 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KIK54027.1 - 0.00027 21.0 0.0 0.00087 19.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KIK54027.1 - 0.00036 20.1 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KIK54027.1 - 0.00045 20.5 0.0 0.0007 19.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KIK54027.1 - 0.0066 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 KIK54027.1 - 0.02 15.7 0.0 0.036 14.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SL4P PF17618.2 KIK54027.1 - 0.039 14.0 0.1 0.76 9.9 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein F420_oxidored PF03807.17 KIK54027.1 - 0.095 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_16 PF13191.6 KIK54029.1 - 3.4e-06 27.5 0.0 4.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK54029.1 - 1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK54029.1 - 0.00063 19.0 0.0 0.00071 18.8 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KIK54029.1 - 0.0011 18.8 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIK54029.1 - 0.0049 16.8 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.6 KIK54029.1 - 0.0094 16.2 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK54029.1 - 0.011 15.0 0.1 0.02 14.0 0.1 1.4 2 0 0 2 2 2 0 PIF1-like helicase NTPase_1 PF03266.15 KIK54029.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF815 PF05673.13 KIK54029.1 - 0.011 14.9 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK54029.1 - 0.018 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KIK54029.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 KIK54029.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KIK54029.1 - 0.039 14.5 0.1 0.071 13.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KIK54029.1 - 0.047 13.6 0.0 0.091 12.7 0.0 1.5 1 1 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KIK54029.1 - 0.055 13.9 0.3 0.14 12.5 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIK54029.1 - 0.068 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KIK54029.1 - 0.079 13.3 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK54029.1 - 0.083 13.4 0.8 0.13 12.8 0.8 1.6 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KIK54029.1 - 0.12 12.2 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KIK54029.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK54029.1 - 0.16 12.0 0.1 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NPL PF17800.1 KIK54031.1 - 2.3e-05 24.9 0.0 4.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin-like domain Arm PF00514.23 KIK54033.1 - 4.6e-35 118.6 0.1 9.9e-12 44.5 0.0 3.2 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK54033.1 - 1.4e-09 38.2 1.0 3.9e-05 24.0 0.0 3.3 2 1 2 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 KIK54033.1 - 1.9e-07 31.4 0.0 0.014 15.8 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KIK54033.1 - 8.5e-05 22.5 0.3 1.6 9.2 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat RICTOR_V PF14668.6 KIK54033.1 - 9.7e-05 22.5 1.3 0.011 15.9 0.0 2.7 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KIK54033.1 - 0.02 15.5 0.5 15 6.6 0.0 3.4 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat Arm_2 PF04826.13 KIK54033.1 - 0.11 11.9 0.1 1.1 8.7 0.0 2.0 1 1 0 2 2 2 0 Armadillo-like DHHC PF01529.20 KIK54035.1 - 3.3e-30 104.9 8.6 3.3e-30 104.9 8.6 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Pam17 PF08566.10 KIK54035.1 - 0.081 12.8 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Aldedh PF00171.22 KIK54036.1 - 1.6e-62 211.5 0.0 2e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MutS_V PF00488.21 KIK54037.1 - 4.6e-63 212.7 0.1 7.6e-63 212.0 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK54037.1 - 4e-24 85.9 0.1 9.4e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIK54037.1 - 3.9e-17 62.5 0.6 1.6e-15 57.3 0.3 2.5 1 1 1 2 2 2 1 MutS domain I MutS_II PF05188.17 KIK54037.1 - 5.8e-09 36.4 0.0 6.4e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KIK54037.1 - 0.00043 20.6 0.0 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 KIK54037.1 - 0.17 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BLOC1S3 PF15753.5 KIK54037.1 - 0.8 9.8 5.5 2.4 8.2 5.5 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 AAA_23 PF13476.6 KIK54037.1 - 1.8 9.0 4.8 7.9 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2235 PF09994.9 KIK54038.1 - 1e-54 185.8 0.0 1.4e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Thioesterase PF00975.20 KIK54038.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Glyco_transf_52 PF07922.11 KIK54039.1 - 0.18 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 52 AAA_30 PF13604.6 KIK54042.1 - 0.0041 16.9 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK54042.1 - 0.0097 15.1 0.5 0.12 11.5 0.2 2.0 1 1 1 2 2 2 1 PIF1-like helicase AAA_14 PF13173.6 KIK54042.1 - 0.014 15.5 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KIK54042.1 - 0.11 12.2 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.6 KIK54042.1 - 0.11 12.9 0.1 0.17 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Helitron_like_N PF14214.6 KIK54045.1 - 1e-13 51.9 0.1 1.8e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK54046.1 - 1.6e-06 27.5 0.1 1.6e-06 27.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK54046.1 - 1.3e-05 25.0 0.0 1.5e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK54046.1 - 0.003 17.9 0.0 0.0033 17.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK54046.1 - 0.0036 17.7 0.0 0.0036 17.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KIK54046.1 - 0.0059 15.6 0.0 0.0063 15.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 KIK54046.1 - 0.026 13.4 0.0 0.029 13.3 0.0 1.0 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KIK54046.1 - 0.043 13.6 0.1 0.051 13.3 0.1 1.3 1 1 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK54046.1 - 0.059 13.5 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase LpxK PF02606.14 KIK54046.1 - 0.062 12.4 0.0 0.072 12.2 0.0 1.0 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase MobB PF03205.14 KIK54046.1 - 0.069 13.1 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 KIK54046.1 - 0.071 12.8 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KIK54046.1 - 0.077 12.2 0.0 0.085 12.0 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 KIK54046.1 - 0.085 12.4 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_RecD PF05127.14 KIK54046.1 - 0.092 12.6 0.1 0.097 12.5 0.1 1.0 1 0 0 1 1 1 0 Helicase Zeta_toxin PF06414.12 KIK54046.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 KIK54046.1 - 0.11 12.2 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KIK54046.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Guanylate_kin PF00625.21 KIK54046.1 - 0.14 11.9 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Guanylate kinase AAA_7 PF12775.7 KIK54046.1 - 0.14 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 KIK54046.1 - 0.16 12.0 0.1 0.19 11.8 0.1 1.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 KIK54047.1 - 0.0059 16.4 0.5 0.028 14.2 0.1 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KIK54047.1 - 0.17 11.7 0.5 0.44 10.4 0.2 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain zf-MYND PF01753.18 KIK54048.1 - 0.035 14.2 2.0 0.035 14.2 2.0 3.0 3 0 0 3 3 3 0 MYND finger GEMIN8 PF15348.6 KIK54050.1 - 0.71 10.1 8.5 0.77 10.0 8.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Cupin_2 PF07883.11 KIK54052.1 - 1.7e-08 34.1 0.9 3.4e-08 33.1 0.4 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KIK54052.1 - 0.00094 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Cupin AMP-binding PF00501.28 KIK54053.1 - 9.7e-68 228.7 0.0 1.2e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK54053.1 - 1.9e-14 54.3 0.1 4.4e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DDE_3 PF13358.6 KIK54055.1 - 5.8e-07 29.4 0.0 6.3e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_4 PF13637.6 KIK54056.1 - 9.4e-23 80.3 5.7 7.3e-08 32.8 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54056.1 - 4.7e-18 63.4 7.2 0.014 15.8 0.3 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KIK54056.1 - 1.1e-16 60.5 10.2 0.021 15.3 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 KIK54056.1 - 8.6e-16 58.3 5.9 6.1e-11 42.8 0.9 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK54056.1 - 6.3e-08 32.7 5.7 0.00031 21.0 0.6 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) YajC PF02699.15 KIK54056.1 - 0.045 13.6 1.7 59 3.7 0.0 3.7 2 1 2 4 4 4 0 Preprotein translocase subunit Toprim_3 PF13362.6 KIK54056.1 - 0.23 11.9 2.0 11 6.5 0.0 2.6 2 1 1 3 3 3 0 Toprim domain WD40 PF00400.32 KIK54057.1 - 1.7e-163 525.5 90.2 1e-10 42.0 0.6 17.7 18 0 0 18 18 17 16 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54057.1 - 4.6e-49 164.7 5.3 0.038 14.3 0.0 15.3 1 1 15 16 16 16 14 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK54057.1 - 2.8e-26 92.3 19.4 0.35 9.8 0.0 14.2 1 1 11 14 14 14 12 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK54057.1 - 1.1e-25 90.7 0.1 6.4e-05 22.9 0.0 6.5 2 1 4 7 7 7 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK54057.1 - 4.4e-19 67.9 25.4 6.3 6.9 0.2 15.3 16 0 0 16 16 15 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK54057.1 - 5.1e-14 51.5 0.0 3.1 6.0 0.0 9.8 1 1 11 13 13 13 8 WD repeat-containing and planar cell polarity effector protein Fritz DUF5643 PF18705.1 KIK54057.1 - 2.4e-09 37.2 0.0 11 6.1 0.0 10.4 9 2 3 12 12 12 0 Family of unknown function (DUF5643) NACHT PF05729.12 KIK54057.1 - 2.2e-07 30.9 0.2 5.1e-07 29.8 0.2 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK54057.1 - 3.5e-05 24.2 0.0 9.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK54057.1 - 0.00013 21.7 1.2 76 3.5 0.1 6.8 7 0 0 7 7 7 0 PQQ enzyme repeat NTPase_1 PF03266.15 KIK54057.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 KIK54057.1 - 0.0099 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK54057.1 - 0.014 14.6 0.4 0.063 12.4 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KIK54057.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK54057.1 - 0.058 13.8 0.3 0.37 11.2 0.1 2.6 2 0 0 2 2 2 0 RNA helicase PQQ_3 PF13570.6 KIK54057.1 - 0.068 13.7 11.8 13 6.4 0.1 7.6 7 2 2 9 9 9 0 PQQ-like domain PQQ_2 PF13360.6 KIK54057.1 - 2.6 7.6 23.4 2.4 7.7 4.5 4.9 2 1 3 5 5 5 0 PQQ-like domain PGM_PMM_I PF02878.16 KIK54060.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I MutS_V PF00488.21 KIK54062.1 - 3.5e-63 213.1 0.2 7.9e-63 211.9 0.1 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIK54062.1 - 2.2e-37 129.1 0.1 5.8e-37 127.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIK54062.1 - 1.6e-33 115.3 0.0 3.8e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIK54062.1 - 8.7e-09 35.8 0.0 1.9e-07 31.4 0.0 2.5 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KIK54062.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KIK54062.1 - 6.4 7.2 6.6 8 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain eIF-3c_N PF05470.12 KIK54062.1 - 7.2 4.8 9.7 6 5.1 7.8 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2235 PF09994.9 KIK54063.1 - 1.2e-58 198.8 0.0 1.5e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UspA1_rep PF18792.1 KIK54063.1 - 0.084 13.4 1.1 0.22 12.1 1.1 1.7 1 0 0 1 1 1 0 Ubiquitous surface protein adhesin repeat Pkinase_fungal PF17667.1 KIK54064.1 - 7.2e-12 44.8 0.0 4.8e-11 42.1 0.1 1.8 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIK54065.1 - 3.8e-12 45.7 0.0 4.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF2235 PF09994.9 KIK54067.1 - 1.4e-76 257.6 0.0 1.8e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1899 PF08953.11 KIK54070.1 - 1.1e-27 95.7 0.1 2.6e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KIK54070.1 - 1e-17 63.7 0.3 2.6e-17 62.4 0.3 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KIK54070.1 - 1.3e-15 57.5 11.0 8.5e-05 23.3 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54070.1 - 3.4e-06 27.2 0.1 0.26 11.6 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK54070.1 - 0.21 10.2 0.2 9.6 4.7 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Cep57_CLD_2 PF14197.6 KIK54070.1 - 0.41 10.8 5.9 0.76 9.9 5.9 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Ank_4 PF13637.6 KIK54071.1 - 6.8e-25 87.1 5.4 1e-09 38.7 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK54071.1 - 3.6e-22 78.7 7.1 1.5e-14 54.3 0.1 3.0 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK54071.1 - 6.4e-18 64.3 5.9 0.0078 16.6 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KIK54071.1 - 4.9e-17 60.3 1.8 0.0074 16.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KIK54071.1 - 3.8e-05 23.9 6.6 0.086 13.2 0.5 4.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF2200 PF09966.9 KIK54071.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) NACHT PF05729.12 KIK54072.1 - 0.012 15.6 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KIK54072.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Melibiase_2 PF16499.5 KIK54073.1 - 4.8e-59 199.9 0.6 7.4e-59 199.2 0.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIK54073.1 - 1.7e-13 50.4 0.0 4.7e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIK54073.1 - 0.00015 20.8 0.1 0.00029 19.9 0.0 1.4 2 0 0 2 2 2 1 Melibiase Amidase PF01425.21 KIK54075.1 - 1.5e-79 268.1 0.0 1.6e-77 261.4 0.0 2.0 1 1 0 1 1 1 1 Amidase DUF2235 PF09994.9 KIK54077.1 - 9e-17 61.3 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-CSL PF05207.13 KIK54078.1 - 0.14 11.9 0.9 0.21 11.4 0.9 1.3 1 0 0 1 1 1 0 CSL zinc finger GTP_cyclohydroI PF01227.22 KIK54080.1 - 0.051 13.0 0.2 0.06 12.8 0.2 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I DUF2235 PF09994.9 KIK54081.1 - 3.5e-60 203.8 0.0 5.4e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK54082.1 - 2e-48 165.2 0.0 2.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK54083.1 - 3.9e-76 256.1 0.0 5e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_S28 PF05577.12 KIK54084.1 - 4.4e-48 164.2 0.2 3.8e-36 124.8 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK54084.1 - 0.00011 21.7 0.1 0.00023 20.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 KIK54084.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KIK54084.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase_fungal PF17667.1 KIK54085.1 - 1.9e-37 129.0 0.0 1.1e-31 110.1 0.0 2.8 1 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK54085.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK54085.1 - 0.14 12.1 0.4 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PHC2_SAM_assoc PF16616.5 KIK54085.1 - 1.1 10.1 5.9 2.2 9.1 5.9 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF1679 PF07914.11 KIK54086.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Lactamase_B PF00753.27 KIK54087.1 - 2.3e-12 47.4 0.2 3.7e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK54087.1 - 6.2e-05 22.6 0.1 0.00012 21.7 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIK54087.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain GCV_T PF01571.21 KIK54089.1 - 2.8e-85 285.8 0.0 3.5e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIK54089.1 - 1.2e-23 82.8 0.0 2.8e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Lactamase_B PF00753.27 KIK54090.1 - 1.7e-10 41.2 0.7 4.1e-10 40.0 0.7 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK54090.1 - 1.9e-05 24.3 0.1 3.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.25 KIK54093.1 - 3e-42 144.8 0.0 3.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54093.1 - 7.8e-29 100.7 0.0 8.7e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK54093.1 - 1.9e-07 30.7 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK54093.1 - 0.0002 20.3 0.0 0.00023 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK54093.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK54093.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK54093.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK54093.1 - 0.07 12.2 0.1 0.12 11.4 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KIK54093.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Lactamase_B PF00753.27 KIK54095.1 - 5.9e-13 49.3 0.0 1.1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK54095.1 - 0.0002 20.9 0.1 0.00041 19.9 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SIS PF01380.22 KIK54096.1 - 2.7e-62 208.4 0.1 1.6e-33 115.4 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KIK54096.1 - 3.4e-15 56.4 0.0 7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIK54096.1 - 5.9e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIK54096.1 - 4.8e-05 22.4 0.0 8.1e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II FAS_N PF17828.1 KIK54096.1 - 0.061 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Esterase PF00756.20 KIK54097.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Putative esterase Lactamase_B PF00753.27 KIK54098.1 - 7.2e-13 49.0 0.1 1.2e-12 48.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK54098.1 - 0.00037 20.1 0.1 0.00083 18.9 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK54099.1 - 9.2e-11 42.1 0.1 1.5e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK54099.1 - 0.00039 20.0 0.0 0.00083 18.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIK54099.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain COesterase PF00135.28 KIK54100.1 - 2.9e-79 267.3 0.1 2e-78 264.6 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK54100.1 - 2.7e-07 30.6 0.2 1.9e-06 27.9 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold ABM PF03992.16 KIK54101.1 - 8e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase F-box-like PF12937.7 KIK54102.1 - 4.3e-07 29.7 3.7 4.3e-07 29.7 3.7 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK54102.1 - 0.012 15.5 2.5 0.77 9.7 0.1 2.9 2 0 0 2 2 2 0 F-box domain COG5 PF10392.9 KIK54102.1 - 0.045 13.9 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Sortilin-Vps10 PF15902.5 KIK54103.1 - 2.5e-288 956.0 3.1 3.6e-147 490.7 0.0 2.3 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KIK54103.1 - 1.6e-95 318.2 15.3 7.4e-52 176.1 2.2 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KIK54103.1 - 2.5e-09 35.7 37.9 3.5 8.0 0.1 12.0 11 0 0 11 11 11 5 BNR/Asp-box repeat PSII_BNR PF14870.6 KIK54103.1 - 0.00064 19.1 0.1 2.6 7.2 0.0 3.9 4 0 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 KIK54103.1 - 0.00065 19.1 6.4 2.3 7.5 0.0 6.0 6 1 0 6 6 6 2 BNR repeat-like domain CHB_HEX_C PF03174.13 KIK54103.1 - 0.00068 19.6 3.0 2.9 7.9 0.0 5.2 6 0 0 6 6 6 2 Chitobiase/beta-hexosaminidase C-terminal domain Fe_dep_repr_C PF02742.15 KIK54103.1 - 0.012 15.6 0.0 1.8 8.7 0.0 3.2 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain CorA PF01544.18 KIK54103.1 - 0.19 11.0 0.7 0.31 10.3 0.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mo-co_dimer PF03404.16 KIK54103.1 - 0.44 10.6 2.1 41 4.2 0.1 4.6 6 1 1 7 7 7 0 Mo-co oxidoreductase dimerisation domain DUF4131 PF13567.6 KIK54103.1 - 0.7 9.5 2.4 5 6.8 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TPR_12 PF13424.6 KIK54105.1 - 7.3e-28 96.7 23.4 1.7e-12 47.5 2.1 5.3 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK54105.1 - 1e-15 56.5 23.1 0.0015 18.5 0.4 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KIK54105.1 - 1.6e-15 56.4 11.9 0.011 15.6 0.3 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54105.1 - 6.5e-14 51.1 17.1 0.0012 18.6 0.2 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 KIK54105.1 - 1.7e-11 43.8 0.0 6e-11 42.0 0.0 2.0 2 1 0 2 2 2 1 NB-ARC domain TPR_8 PF13181.6 KIK54105.1 - 9.8e-08 31.6 14.9 1.4 9.3 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.6 KIK54105.1 - 3.7e-07 29.8 11.8 0.0012 18.3 0.2 3.2 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KIK54105.1 - 2.8e-06 26.9 4.4 0.0027 17.1 0.1 3.0 1 1 2 3 3 3 3 MalT-like TPR region AAA_16 PF13191.6 KIK54105.1 - 5.2e-06 27.0 0.4 6.3e-05 23.4 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KIK54105.1 - 1.3e-05 25.6 12.9 0.058 13.9 0.1 6.0 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK54105.1 - 1.7e-05 24.5 14.3 0.11 12.6 0.2 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat AAA_22 PF13401.6 KIK54105.1 - 0.00038 20.7 0.2 0.0032 17.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain TPR_14 PF13428.6 KIK54105.1 - 0.0017 19.0 14.0 12 7.0 0.0 6.3 6 1 1 7 7 5 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KIK54105.1 - 0.022 14.7 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_21 PF09976.9 KIK54105.1 - 0.045 13.5 9.4 0.19 11.4 0.7 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain NACHT PF05729.12 KIK54105.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF4056 PF13265.6 KIK54105.1 - 0.086 12.2 0.5 4.2 6.6 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF4056) AAA_24 PF13479.6 KIK54105.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 KIK54105.1 - 0.39 11.4 13.1 7.1 7.4 0.1 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK54105.1 - 2.1 8.1 9.5 10 5.9 0.4 5.0 4 2 1 5 5 5 0 TPR repeat ANAPC3 PF12895.7 KIK54105.1 - 2.6 8.3 13.1 3.7 7.9 1.0 4.1 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF677 PF05055.12 KIK54105.1 - 2.8 6.7 7.0 0.41 9.5 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF677) TPR_17 PF13431.6 KIK54105.1 - 5.9 7.5 10.3 13 6.4 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat p450 PF00067.22 KIK54106.1 - 3.3e-64 217.3 0.0 4.1e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PTS_IIB PF02302.17 KIK54106.1 - 0.14 12.9 0.4 0.64 10.8 0.2 2.2 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit TPR_10 PF13374.6 KIK54107.1 - 4.4e-81 264.8 3.0 1.3e-07 31.2 0.0 12.3 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54107.1 - 4.1e-67 222.5 16.5 2.3e-11 43.8 0.0 9.5 3 2 9 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.6 KIK54107.1 - 3.8e-12 45.3 4.9 1.9 8.7 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK54107.1 - 3.9e-12 45.3 7.4 1.7 8.9 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK54107.1 - 8.5e-11 41.2 6.2 1.5 9.2 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54107.1 - 1.1e-10 40.9 12.5 0.73 9.8 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK54107.1 - 1.3e-08 35.0 4.9 0.02 15.1 1.3 6.0 5 2 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK54107.1 - 5.7e-08 33.2 2.3 5.2 7.7 0.0 7.5 5 4 3 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK54107.1 - 1e-07 31.7 7.1 0.01 15.2 0.9 3.6 2 2 1 3 3 3 3 MalT-like TPR region TPR_20 PF14561.6 KIK54107.1 - 2.7e-07 30.8 0.7 26 5.2 0.0 8.2 3 2 6 10 10 9 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK54107.1 - 4.9e-07 29.8 0.3 0.15 12.2 0.0 4.6 3 1 1 4 4 4 2 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 KIK54107.1 - 1.2e-06 28.4 0.4 25 5.1 0.0 7.4 10 0 0 10 10 6 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KIK54107.1 - 0.00012 22.6 0.9 4.7 7.6 0.0 5.2 4 1 0 5 5 5 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 KIK54107.1 - 0.00012 22.5 0.4 22 6.0 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat PAD_M PF08527.10 KIK54107.1 - 0.00012 21.7 3.3 0.21 11.2 0.1 4.0 1 1 0 3 3 3 2 Protein-arginine deiminase (PAD) middle domain TPR_5 PF12688.7 KIK54107.1 - 0.00022 21.5 0.4 0.7 10.2 0.0 3.9 4 1 1 5 5 4 1 Tetratrico peptide repeat YqaH PF17448.2 KIK54107.1 - 0.00035 20.8 0.2 14 6.1 0.0 5.9 3 2 5 8 8 8 0 Uncharacterized YqaH-like PPR PF01535.20 KIK54107.1 - 0.00047 20.2 4.0 26 5.3 0.1 7.4 10 0 0 10 10 7 0 PPR repeat TPR_17 PF13431.6 KIK54107.1 - 0.00057 20.1 18.1 1.4 9.5 0.1 8.3 10 0 0 10 10 8 1 Tetratricopeptide repeat DUF3400 PF11880.8 KIK54107.1 - 0.00072 19.0 0.6 91 2.7 0.0 6.7 9 0 0 9 9 7 0 Domain of unknown function (DUF3400) Foie-gras_1 PF11817.8 KIK54107.1 - 0.0017 18.0 1.2 16 5.0 0.0 5.5 6 0 0 6 6 6 0 Foie gras liver health family 1 Vps39_1 PF10366.9 KIK54107.1 - 0.0053 17.0 11.9 0.087 13.1 0.1 6.1 2 2 6 9 9 9 1 Vacuolar sorting protein 39 domain 1 DUF4071 PF13281.6 KIK54107.1 - 0.0069 15.5 4.9 0.062 12.3 0.5 3.2 1 1 2 4 4 4 1 Domain of unknown function (DUF4071) DUF627 PF04781.12 KIK54107.1 - 0.013 15.5 0.0 8.6 6.4 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF627) Paf67 PF10255.9 KIK54107.1 - 0.014 14.4 0.1 1.8 7.5 0.0 2.9 2 1 1 3 3 3 0 RNA polymerase I-associated factor PAF67 FAM153 PF15722.5 KIK54107.1 - 0.014 15.7 0.3 0.25 11.7 0.1 2.5 2 0 0 2 2 2 0 FAM153 family SBF2 PF12335.8 KIK54107.1 - 0.034 13.8 1.1 0.87 9.2 0.1 2.9 3 0 0 3 3 3 0 Myotubularin protein CODH_A_N PF18537.1 KIK54107.1 - 0.045 13.8 0.0 6 7.0 0.0 3.3 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain PPR_2 PF13041.6 KIK54107.1 - 0.11 12.7 0.5 8.2 6.7 0.0 3.9 3 1 1 4 4 3 0 PPR repeat family DUF4919 PF16266.5 KIK54107.1 - 0.28 11.1 2.3 16 5.4 0.0 4.1 5 1 1 6 6 6 0 Domain of unknown function (DUF4919) TPR_11 PF13414.6 KIK54107.1 - 1.9 8.2 8.8 31 4.4 0.0 5.4 7 0 0 7 7 6 0 TPR repeat NACHT PF05729.12 KIK54111.1 - 6.4e-12 45.7 0.1 9.5e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK54111.1 - 6.8e-05 23.3 0.0 0.00021 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK54111.1 - 0.00034 21.0 0.0 0.0013 19.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK54111.1 - 0.00048 20.1 0.0 0.00088 19.3 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK54111.1 - 0.0009 19.6 0.0 0.0045 17.3 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KIK54111.1 - 0.0017 18.4 0.0 0.74 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KIK54111.1 - 0.0092 15.7 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.6 KIK54111.1 - 0.02 15.2 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK54111.1 - 0.042 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIK54111.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK54111.1 - 0.091 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK54111.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region APS_kinase PF01583.20 KIK54111.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KIK54111.1 - 0.2 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK54111.1 - 0.29 10.3 1.4 7.6 5.7 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain WD40 PF00400.32 KIK54112.1 - 6.1e-38 128.2 26.6 3.3e-10 40.4 0.6 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54112.1 - 1.1e-17 64.1 0.1 0.0033 17.7 0.1 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK54112.1 - 2.8e-11 43.0 2.1 0.04 12.9 0.0 4.2 2 2 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK54112.1 - 4.1e-08 33.0 3.8 2.2 8.3 0.0 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK54112.1 - 0.00017 21.5 3.1 0.022 14.5 2.4 3.9 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK54112.1 - 0.0097 15.3 0.1 20 4.4 0.0 3.7 3 1 1 4 4 4 0 WD40-like domain eIF2A PF08662.11 KIK54112.1 - 0.018 14.9 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK54112.1 - 0.019 13.6 4.0 8.4 4.9 0.0 3.9 3 2 1 5 5 5 0 Nucleoporin Nup120/160 Frtz PF11768.8 KIK54112.1 - 0.089 11.1 0.0 8.6 4.5 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK54112.1 - 8.8 6.1 5.7 1.5e+02 2.2 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KIK54113.1 - 0.088 12.7 0.0 0.093 12.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain ArsC PF03960.15 KIK54113.1 - 0.091 12.8 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 ArsC family G-alpha PF00503.20 KIK54115.1 - 2.5e-110 369.0 0.0 3.1e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK54115.1 - 1e-12 47.9 0.0 9e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK54115.1 - 0.018 15.3 0.0 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK54115.1 - 0.033 13.5 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KIK54115.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3490 PF11995.8 KIK54117.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) TRI5 PF06330.11 KIK54119.1 - 2.8e-14 52.8 0.0 3.4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.11 KIK54120.1 - 6.2e-14 51.6 0.1 7.7e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.22 KIK54121.1 - 1.1e-61 209.0 0.0 1.4e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.22 KIK54122.1 - 1.3e-05 24.7 0.1 0.00029 20.3 0.1 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GMC_oxred_N PF00732.19 KIK54123.1 - 3e-60 204.1 0.0 4.3e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK54123.1 - 5e-33 114.6 0.6 1.9e-32 112.8 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK54123.1 - 0.0034 16.5 0.1 0.0052 15.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein EFG_C PF00679.24 KIK54124.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Elongation factor G C-terminus p450 PF00067.22 KIK54125.1 - 3e-52 177.9 0.0 3.6e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIK54126.1 - 2.4e-60 204.5 0.0 3.8e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK54126.1 - 5.2e-31 108.1 0.1 9.3e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK54126.1 - 5.1e-05 22.5 0.1 0.00011 21.5 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DEAD PF00270.29 KIK54129.1 - 4.6e-42 143.7 0.0 7.6e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK54129.1 - 1.4e-28 99.5 0.3 3.5e-27 95.0 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain tRNA-synt_1b PF00579.25 KIK54129.1 - 0.14 11.5 0.0 1.5 8.0 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) NgoMIV_restric PF09015.10 KIK54133.1 - 0.026 13.6 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme CorA PF01544.18 KIK54135.1 - 4.9e-29 101.6 6.0 2.9e-26 92.5 3.3 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF4660 PF15559.6 KIK54135.1 - 0.033 14.5 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) FMN_dh PF01070.18 KIK54136.1 - 6.1e-109 364.2 0.0 7.7e-109 363.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK54136.1 - 4.8e-20 71.5 0.0 8.5e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIK54136.1 - 8.3e-06 25.2 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIK54136.1 - 0.00028 20.0 0.2 0.00097 18.2 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KIK54136.1 - 0.00032 20.2 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase AflR PF08493.10 KIK54137.1 - 0.063 12.7 3.1 0.071 12.6 3.1 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein PPR_long PF17177.4 KIK54140.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP S1-like PF14444.6 KIK54142.1 - 0.0038 17.1 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 S1-like F-box-like PF12937.7 KIK54142.1 - 0.082 12.8 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 F-box-like KDZ PF18758.1 KIK54145.1 - 2.4e-05 24.1 0.7 2.8e-05 23.8 0.7 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Glyco_transf_25 PF01755.17 KIK54145.1 - 0.008 16.1 0.8 0.012 15.5 0.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF5320 PF17253.2 KIK54149.1 - 0.11 13.5 1.1 0.32 12.1 1.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) PBP1_TM PF14812.6 KIK54149.1 - 0.14 12.6 8.1 0.19 12.1 2.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KIK54149.1 - 0.34 10.6 4.5 0.73 9.5 0.1 2.1 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KIK54149.1 - 1.2 9.5 7.5 0.16 12.3 3.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DivIC PF04977.15 KIK54149.1 - 1.5 8.6 5.7 3 7.7 5.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Rep_fac-A_3 PF08661.11 KIK54150.1 - 0.0018 18.6 0.0 0.0066 16.8 0.0 1.9 1 0 0 1 1 1 1 Replication factor A protein 3 Rho_Binding PF08912.11 KIK54150.1 - 0.1 13.4 4.8 0.26 12.1 4.8 1.6 1 0 0 1 1 1 0 Rho Binding Caleosin PF05042.13 KIK54154.1 - 1.1e-45 155.6 0.2 4.5e-40 137.3 0.1 2.2 2 0 0 2 2 2 2 Caleosin related protein RTA1 PF04479.13 KIK54155.1 - 4.2e-52 176.8 7.9 6.5e-52 176.2 7.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Syndecan PF01034.20 KIK54155.1 - 1.1 9.2 2.8 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain Glyco_hydro_18 PF00704.28 KIK54156.1 - 3.6e-15 56.5 0.3 4.4e-15 56.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tetraspanin PF00335.20 KIK54158.1 - 0.068 12.9 0.2 0.068 12.9 0.2 1.8 2 0 0 2 2 2 0 Tetraspanin family Jiraiya PF15038.6 KIK54158.1 - 0.36 10.3 3.3 0.2 11.1 0.4 2.0 2 0 0 2 2 2 0 Jiraiya zf_UBZ PF18439.1 KIK54159.1 - 0.002 17.7 4.8 4.5 7.0 0.1 4.1 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger DUF5627 PF18620.1 KIK54159.1 - 0.002 18.0 2.2 1.3 8.9 0.2 3.7 1 1 2 3 3 3 1 Family of unknown function (DUF5627) TOH_N PF12549.8 KIK54159.1 - 0.011 15.6 0.1 90 3.1 0.0 4.8 5 0 0 5 5 5 0 Tyrosine hydroxylase N terminal KIP1 PF07765.12 KIK54159.1 - 1.4 9.1 10.5 8.3 6.6 0.2 3.7 2 1 2 4 4 4 0 KIP1-like protein Longin_2 PF18639.1 KIK54159.1 - 1.7 8.5 6.4 13 5.6 0.6 3.6 1 1 2 3 3 3 0 Yeast longin domain FAM220 PF15487.6 KIK54159.1 - 2.2 7.8 8.2 31 4.1 0.2 3.6 1 1 2 4 4 4 0 FAM220 family Phenol_monoox PF04663.12 KIK54159.1 - 4.1 7.6 13.2 43 4.4 0.2 4.0 2 1 2 4 4 4 0 Phenol hydroxylase conserved region DUF5581 PF17744.1 KIK54159.1 - 7.1 5.9 9.6 15 4.9 0.3 3.4 1 1 3 4 4 4 0 Family of unknown function (DUF5581) Apt1 PF10351.9 KIK54162.1 - 3 6.6 8.9 5.6 5.7 8.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Phosphoesterase PF04185.14 KIK54163.1 - 2.2e-72 244.2 0.1 3.1e-72 243.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 KIK54163.1 - 0.021 15.5 0.0 11 6.8 0.0 2.8 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Phosphoesterase PF04185.14 KIK54164.1 - 2.5e-67 227.6 0.0 3.4e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 KIK54164.1 - 0.011 16.5 0.7 8.8 7.1 0.0 2.8 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Phosphoesterase PF04185.14 KIK54165.1 - 1.2e-64 218.7 0.1 1.7e-64 218.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 KIK54165.1 - 0.0035 18.0 0.1 0.65 10.8 0.0 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Phosphoesterase PF04185.14 KIK54166.1 - 5.7e-74 249.4 0.1 7.7e-74 249.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 KIK54166.1 - 0.003 18.2 1.8 2.6 8.8 0.0 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Cu-oxidase_3 PF07732.15 KIK54167.1 - 9.1e-40 135.4 0.1 9.1e-40 135.4 0.1 2.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK54167.1 - 9.1e-29 99.9 5.1 5.5e-26 90.9 0.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KIK54167.1 - 6.5e-22 78.3 0.0 3.2e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Phage_holin_1 PF04531.13 KIK54170.1 - 1 10.0 5.7 5.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage holin Glyco_hydro_76 PF03663.14 KIK54171.1 - 1.1e-10 41.6 0.2 1.2e-10 41.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.14 KIK54172.1 - 0.01 15.4 0.1 0.016 14.8 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 76 Phosphoesterase PF04185.14 KIK54173.1 - 7.6e-65 219.4 0.1 1.2e-64 218.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 KIK54173.1 - 0.051 14.3 0.0 8 7.3 0.0 2.7 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Phosphoesterase PF04185.14 KIK54174.1 - 1.7e-68 231.4 0.1 2.3e-68 231.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 KIK54174.1 - 0.0011 19.7 1.6 1.4 9.7 0.0 2.9 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_28 PF00295.17 KIK54175.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Sugar_tr PF00083.24 KIK54176.1 - 3.2e-85 286.7 20.1 3.7e-85 286.5 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK54176.1 - 2.2e-28 99.2 48.5 2.5e-25 89.2 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.9 KIK54177.1 - 1.6e-31 109.0 3.8 2.6e-31 108.4 0.0 2.7 2 0 0 2 2 2 1 Autophagy-related protein 11 PPDFL PF15060.6 KIK54177.1 - 0.1 13.1 6.0 0.13 12.8 3.7 2.4 2 0 0 2 2 2 0 Differentiation and proliferation regulator Lipoxygenase PF00305.19 KIK54179.1 - 8.6e-40 136.8 0.1 4.1e-36 124.7 0.1 2.9 2 1 1 3 3 3 3 Lipoxygenase Transket_pyr PF02779.24 KIK54180.1 - 5.4e-59 198.9 0.0 7.6e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KIK54180.1 - 1.1e-42 145.3 0.0 1.7e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KIK54180.1 - 1.2e-25 90.1 0.0 1.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Na_Ca_ex PF01699.24 KIK54181.1 - 1.6e-13 50.8 27.6 9.2e-08 32.2 9.6 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein p450 PF00067.22 KIK54182.1 - 1.8e-67 228.1 0.0 2.1e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KIK54183.1 - 1.9e-15 56.6 0.0 2.5e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) 4HBT_2 PF13279.6 KIK54184.1 - 4.1e-08 33.8 0.0 8.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily HAD PF12710.7 KIK54185.1 - 1.3e-23 84.4 0.0 1.7e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KIK54185.1 - 4.6e-06 26.2 0.0 1.8e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 KIK54185.1 - 7.1e-06 25.7 0.0 1.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KIK54185.1 - 8.6e-06 26.2 0.1 0.00028 21.2 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK54185.1 - 0.00048 20.3 0.1 0.0086 16.2 0.1 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.12 KIK54185.1 - 0.0044 17.3 0.1 0.52 10.6 0.0 2.8 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding DUF2357 PF09823.9 KIK54185.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF2678 PF10856.8 KIK54186.1 - 0.15 12.0 3.2 0.5 10.3 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) RicinB_lectin_2 PF14200.6 KIK54187.1 - 0.00023 21.8 0.0 0.00067 20.3 0.0 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like DUF2678 PF10856.8 KIK54188.1 - 0.51 10.3 6.6 0.13 12.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Abhydrolase_6 PF12697.7 KIK54189.1 - 2.3e-12 48.0 0.2 3e-12 47.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK54189.1 - 1.1e-09 38.3 0.0 2.8e-07 30.4 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK54189.1 - 8.7e-09 35.0 0.0 2.2e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIK54189.1 - 3.9e-05 23.5 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIK54189.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_23 PF13489.6 KIK54190.1 - 2.6e-16 59.9 0.0 4.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK54190.1 - 1.9e-12 47.7 0.0 6.1e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK54190.1 - 3e-12 46.6 0.0 2.8e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK54190.1 - 1.8e-11 44.5 0.0 3.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK54190.1 - 5.9e-09 36.6 0.0 2.2e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIK54190.1 - 0.00018 21.3 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 KIK54190.1 - 0.00099 18.6 0.0 0.0022 17.5 0.0 1.5 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KIK54190.1 - 0.0045 17.1 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIK54190.1 - 0.021 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KIK54190.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KIK54190.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KIK54190.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UPF0506 PF11703.8 KIK54191.1 - 0.0037 17.6 13.9 0.031 14.6 14.1 1.9 1 1 1 2 2 2 1 UPF0506 Conotoxin PF02950.17 KIK54191.1 - 0.049 14.6 3.5 0.049 14.6 3.5 2.2 1 1 1 2 2 2 0 Conotoxin Toxin_12 PF07740.12 KIK54191.1 - 0.73 10.6 16.8 2.2 9.1 4.3 2.5 2 0 0 2 2 2 0 Ion channel inhibitory toxin MIOX PF05153.15 KIK54192.1 - 1.3e-127 424.5 0.7 1.6e-127 424.3 0.7 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KIK54192.1 - 0.0022 18.2 0.1 0.21 11.8 0.1 2.4 1 1 0 1 1 1 1 HD domain UBD PF16455.5 KIK54192.1 - 0.089 13.0 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain Aldo_ket_red PF00248.21 KIK54193.1 - 5.1e-47 160.5 0.0 7.3e-40 137.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family IreB PF06135.12 KIK54193.1 - 0.0021 18.2 0.0 8 6.7 0.0 3.3 3 0 0 3 3 3 2 IreB regulatory phosphoprotein Toxin_12 PF07740.12 KIK54194.1 - 1.8e-08 34.9 29.5 0.00014 22.5 3.9 4.0 3 1 0 3 3 3 3 Ion channel inhibitory toxin Conotoxin PF02950.17 KIK54194.1 - 0.035 15.1 0.8 0.035 15.1 0.8 3.5 2 1 1 3 3 3 0 Conotoxin UPF0506 PF11703.8 KIK54194.1 - 2.6 8.5 24.2 1.1 9.6 2.5 3.9 4 0 0 4 4 4 0 UPF0506 Toxin_12 PF07740.12 KIK54195.1 - 4.7e-07 30.4 17.1 0.00017 22.2 4.1 2.5 1 1 0 2 2 2 2 Ion channel inhibitory toxin Toxin_7 PF05980.12 KIK54195.1 - 0.00054 20.2 16.3 0.0027 17.9 4.3 2.6 2 1 0 2 2 2 2 Toxin 7 Toxin_35 PF10530.9 KIK54195.1 - 0.0088 16.0 3.9 0.0088 16.0 3.9 2.8 1 1 1 2 2 2 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Conotoxin PF02950.17 KIK54195.1 - 0.076 14.0 3.3 0.076 14.0 3.3 2.2 1 1 1 2 2 2 0 Conotoxin Toxin_9 PF02819.15 KIK54195.1 - 0.22 11.8 15.1 0.12 12.6 4.8 2.3 1 1 1 2 2 2 0 Spider toxin Tachystatin_A PF11406.8 KIK54195.1 - 4.5 7.4 15.6 1 9.5 4.1 2.5 1 1 1 2 2 2 0 Antimicrobial peptide tachystatin A Acyl-CoA_dh_1 PF00441.24 KIK54196.1 - 4.9e-27 95.0 0.4 6.3e-27 94.6 0.4 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK54196.1 - 5e-20 71.5 0.0 1.3e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK54196.1 - 1.2e-12 48.3 0.0 1.7e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HAD_2 PF13419.6 KIK54197.1 - 3e-09 37.2 0.0 0.0087 16.2 0.0 3.1 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK54197.1 - 0.0005 20.4 0.0 0.001 19.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase OTT_1508_deam PF14441.6 KIK54198.1 - 0.071 13.1 0.3 0.16 12.0 0.3 1.7 1 0 0 1 1 1 0 OTT_1508-like deaminase gag_pre-integrs PF13976.6 KIK54199.1 - 6e-05 22.8 0.1 7.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain Dyp_perox PF04261.12 KIK54200.1 - 4.6e-09 35.7 0.0 9.1e-08 31.5 0.0 2.5 2 1 0 2 2 2 1 Dyp-type peroxidase family MBA1 PF07961.11 KIK54201.1 - 0.00016 20.8 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein MGC-24 PF05283.11 KIK54202.1 - 0.083 13.3 1.6 0.1 13.0 0.6 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2724 PF10893.8 KIK54202.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Alpha_GJ PF03229.13 KIK54203.1 - 0.0024 18.4 2.0 0.0024 18.4 2.0 2.7 1 1 0 2 2 2 1 Alphavirus glycoprotein J TMEM154 PF15102.6 KIK54203.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.6 1 1 3 4 4 4 0 TMEM154 protein family HAD_2 PF13419.6 KIK54204.1 - 1.8e-08 34.6 0.0 3.5e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK54204.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Con-6 PF10346.9 KIK54205.1 - 1.8e-27 95.0 1.0 1.6e-12 47.2 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Ank_4 PF13637.6 KIK54206.1 - 1.8e-33 114.4 15.7 4.7e-05 23.9 0.1 10.2 2 2 9 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK54206.1 - 1.4e-32 112.1 29.1 2.5e-09 37.6 1.3 5.3 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK54206.1 - 4.4e-23 78.9 25.8 0.042 14.4 0.1 11.7 11 1 1 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KIK54206.1 - 7.1e-13 48.5 22.4 0.0041 17.4 0.3 7.7 3 2 6 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KIK54206.1 - 6.4e-12 45.4 49.4 0.022 15.2 0.5 11.9 12 1 1 13 13 13 6 Ankyrin repeat End_beta_barrel PF12195.8 KIK54206.1 - 0.021 14.7 5.4 49 4.0 0.1 4.9 4 1 1 5 5 5 0 Beta barrel domain of bacteriophage endosialidase Amidinotransf PF02274.17 KIK54206.1 - 0.04 13.0 0.2 3.2 6.8 0.0 2.9 2 1 0 3 3 3 0 Amidinotransferase YajC PF02699.15 KIK54206.1 - 0.089 12.7 2.6 5.1 7.0 0.0 4.0 3 1 2 5 5 5 0 Preprotein translocase subunit Borealin PF10512.9 KIK54206.1 - 0.12 12.4 0.3 21 5.1 0.0 4.3 4 3 3 7 7 7 0 Cell division cycle-associated protein 8 DUF1843 PF08898.10 KIK54206.1 - 0.17 12.4 12.1 1.4 9.5 0.1 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) DUF3710 PF12502.8 KIK54206.1 - 0.27 10.9 4.1 11 5.7 0.2 3.8 2 2 2 5 5 5 0 Protein of unknown function (DUF3710) SWIB PF02201.18 KIK54207.1 - 0.043 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain Retrotrans_gag PF03732.17 KIK54208.1 - 1.4e-07 31.7 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK54208.1 - 0.00012 21.9 3.8 0.00025 21.0 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 KIK54208.1 - 0.0049 16.7 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF648 PF04890.13 KIK54209.1 - 0.016 15.0 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF745 PF05335.13 KIK54209.1 - 0.057 13.1 2.2 1.7 8.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK54209.1 - 0.13 12.2 4.8 5.5 6.9 0.3 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 KIK54209.1 - 0.25 11.4 3.8 0.45 10.6 3.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4503 PF14951.6 KIK54210.1 - 0.65 8.4 2.6 0.96 7.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Ank_4 PF13637.6 KIK54211.1 - 1.9e-08 34.7 0.1 0.00055 20.4 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54211.1 - 4.6e-08 32.7 1.0 0.76 10.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KIK54211.1 - 1.3e-07 32.1 0.5 0.022 15.3 0.0 2.5 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK54211.1 - 5.4e-07 29.8 4.0 0.59 10.7 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat COesterase PF00135.28 KIK54212.1 - 3.3e-91 306.7 0.0 4.9e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK54212.1 - 5e-08 33.1 0.1 2.3e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK54212.1 - 0.00086 18.8 0.0 0.003 17.1 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Con-6 PF10346.9 KIK54213.1 - 8.6e-29 99.3 1.2 2.8e-13 49.7 0.1 2.2 2 0 0 2 2 2 2 Conidiation protein 6 NACHT PF05729.12 KIK54214.1 - 8.4e-12 45.3 0.0 2e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK54214.1 - 4.6e-06 27.1 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK54214.1 - 0.0035 17.6 0.0 0.023 15.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK54214.1 - 0.0043 17.4 0.0 0.021 15.2 0.0 2.2 3 0 0 3 3 3 1 RNA helicase Parvo_NS1 PF01057.17 KIK54214.1 - 0.0048 16.0 0.2 0.0086 15.2 0.2 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK54214.1 - 0.0088 16.5 0.0 0.16 12.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK54214.1 - 0.058 13.4 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIK54214.1 - 0.09 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein APS_kinase PF01583.20 KIK54214.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KIK54214.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_18 PF13238.6 KIK54214.1 - 0.19 12.3 0.0 0.5 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK54214.1 - 0.23 11.0 0.0 1.3 8.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KIK54214.1 - 0.24 11.1 0.0 0.36 10.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.8 KIK54215.1 - 1.1e-08 35.2 0.6 1.8e-08 34.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-CCHC_4 PF14392.6 KIK54215.1 - 0.059 13.1 0.5 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle COesterase PF00135.28 KIK54216.1 - 4.3e-96 322.8 0.0 6.4e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK54216.1 - 3e-08 33.8 0.2 1.7e-07 31.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK54216.1 - 0.0046 16.5 0.2 0.0088 15.5 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Viral_cys_rich PF08008.12 KIK54216.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral cysteine rich COesterase PF00135.28 KIK54217.1 - 1.3e-93 314.6 0.0 2e-93 314.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK54217.1 - 7.8e-11 42.2 0.1 3.5e-10 40.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK54217.1 - 0.00014 21.4 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KIK54217.1 - 0.057 14.0 0.5 0.17 12.5 0.5 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family GATA PF00320.27 KIK54218.1 - 1.5e-07 30.9 7.6 2.6e-07 30.1 7.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Flavin_Reduct PF01613.18 KIK54219.1 - 5.8e-17 62.2 0.0 7.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Thaumatin PF00314.17 KIK54220.1 - 1.2e-59 201.6 9.3 1.4e-59 201.3 9.3 1.1 1 0 0 1 1 1 1 Thaumatin family RhoGEF PF00621.20 KIK54222.1 - 5.6e-16 59.3 1.1 6.7e-16 59.1 0.4 1.5 2 0 0 2 2 2 1 RhoGEF domain FUSC PF04632.12 KIK54222.1 - 0.051 12.1 0.2 0.059 11.9 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family p450 PF00067.22 KIK54223.1 - 1.6e-52 178.8 1.0 6.4e-52 176.8 0.0 2.2 2 1 0 2 2 2 1 Cytochrome P450 CwsA PF10814.8 KIK54223.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA COesterase PF00135.28 KIK54224.1 - 3.5e-91 306.6 0.0 5.1e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK54224.1 - 3.6e-07 30.3 0.2 1.3e-06 28.5 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK54224.1 - 0.00026 20.5 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family TruB_C PF09142.11 KIK54225.1 - 5.4e-09 35.7 1.0 0.076 12.8 0.0 4.7 1 1 3 4 4 4 4 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.12 KIK54225.1 - 4.8e-07 29.5 0.0 34 4.5 0.0 5.4 5 0 0 5 5 5 5 WD40-like Beta Propeller Repeat DUF5122 PF17164.4 KIK54225.1 - 0.00035 20.8 1.2 1.4e+02 2.9 0.0 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller vWF_A PF12450.8 KIK54225.1 - 0.02 14.8 0.5 33 4.5 0.1 3.4 1 1 2 3 3 3 0 von Willebrand factor Ribosomal_L35p PF01632.19 KIK54226.1 - 0.0014 19.1 0.4 0.0021 18.5 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 HAUS6_N PF14661.6 KIK54228.1 - 2.5e-08 33.8 0.1 2.5e-08 33.8 0.1 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus FokI_N PF02981.15 KIK54228.1 - 0.0065 16.6 0.1 0.88 9.7 0.1 2.4 2 0 0 2 2 2 2 Restriction endonuclease FokI, recognition domain SCP-1 PF05483.12 KIK54228.1 - 0.11 10.5 0.1 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Pterin_4a PF01329.19 KIK54229.1 - 5.9e-06 26.4 0.1 0.0002 21.5 0.1 2.6 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase zf-CCHC PF00098.23 KIK54229.1 - 0.0053 16.8 0.5 0.0053 16.8 0.5 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 KIK54229.1 - 0.0053 16.4 0.7 0.0092 15.7 0.7 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger Abhydrolase_1 PF00561.20 KIK54231.1 - 1.7e-13 50.8 0.0 1.2e-12 48.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK54231.1 - 1.1e-06 28.1 0.0 1.5e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIK54231.1 - 0.00034 20.6 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KIK54231.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KIK54231.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK54232.1 - 0.00021 21.1 0.0 0.013 15.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold AbfS_sensor PF18225.1 KIK54236.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain MASE1 PF05231.14 KIK54239.1 - 0.00055 19.2 3.8 0.00078 18.7 3.8 1.2 1 0 0 1 1 1 1 MASE1 DUF5090 PF17009.5 KIK54239.1 - 0.35 10.8 2.5 0.46 10.4 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) NACHT PF05729.12 KIK54240.1 - 2e-09 37.6 0.0 3.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KIK54240.1 - 7.9e-05 22.7 0.0 0.004 17.2 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK54240.1 - 0.0033 17.8 0.0 0.0099 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK54240.1 - 0.0081 16.4 0.1 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KIK54240.1 - 0.0083 15.4 0.0 0.018 14.3 0.0 1.5 1 1 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 KIK54240.1 - 0.0086 15.3 0.0 0.022 13.9 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 KIK54240.1 - 0.01 15.1 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KIK54240.1 - 0.016 15.1 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KIK54240.1 - 0.033 13.4 0.0 0.081 12.1 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase ATPase PF06745.13 KIK54240.1 - 0.036 13.4 0.1 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 KIK54240.1 - 0.06 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 KIK54240.1 - 0.086 12.8 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KIK54240.1 - 0.091 12.0 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KIK54240.1 - 0.1 12.0 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3970 PF13113.6 KIK54240.1 - 0.16 12.2 0.0 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) DUF758 PF05527.11 KIK54241.1 - 0.027 14.5 0.3 0.04 13.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF758) DRMBL PF07522.14 KIK54242.1 - 0.04 14.1 0.0 8.8 6.6 0.0 2.1 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase 7TMR-DISM_7TM PF07695.11 KIK54243.1 - 0.0038 17.2 4.4 0.0049 16.8 4.4 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling Dicty_CAR PF05462.11 KIK54243.1 - 0.017 14.3 0.5 0.021 14.0 0.5 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Ferric_reduct PF01794.19 KIK54243.1 - 0.043 13.9 1.9 0.079 13.1 1.9 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Maf_N PF08383.11 KIK54245.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 Maf N-terminal region Pro_isomerase PF00160.21 KIK54246.1 - 1.2e-10 41.9 0.0 1.5e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NACHT PF05729.12 KIK54248.1 - 2.8e-10 40.4 0.0 5.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KIK54248.1 - 0.00013 22.0 0.0 0.00062 19.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KIK54248.1 - 0.00053 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK54248.1 - 0.021 15.2 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KIK54248.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AhpC-TSA PF00578.21 KIK54248.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family AAA_22 PF13401.6 KIK54248.1 - 0.069 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK54248.1 - 0.074 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.6 KIK54248.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Pro_isomerase PF00160.21 KIK54251.1 - 6.5e-09 36.3 0.0 6.9e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_2 PF07723.13 KIK54252.1 - 0.28 11.9 3.2 3.5 8.4 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Prok_Ub PF14454.6 KIK54254.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic Ubiquitin Ank_2 PF12796.7 KIK54256.1 - 1.2e-72 240.5 46.6 2.5e-13 50.4 1.7 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54256.1 - 1e-48 163.1 6.2 1.1e-06 29.1 0.1 9.1 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54256.1 - 2.8e-36 119.4 13.3 0.032 14.7 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank PF00023.30 KIK54256.1 - 6.2e-29 99.2 32.1 0.016 15.7 0.1 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 KIK54256.1 - 1.3e-17 63.6 18.8 0.003 17.8 0.3 7.9 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Coatomer_b_Cpla PF14806.6 KIK54256.1 - 0.0094 15.9 1.6 10 6.1 0.0 3.8 3 1 1 4 4 4 1 Coatomer beta subunit appendage platform DUF4424 PF14415.6 KIK54256.1 - 0.011 15.1 0.3 2.8 7.1 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4424) DUF1966 PF09260.11 KIK54256.1 - 0.023 15.0 0.3 11 6.3 0.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1966) Borealin PF10512.9 KIK54256.1 - 0.091 12.7 0.1 27 4.8 0.0 3.7 4 0 0 4 4 4 0 Cell division cycle-associated protein 8 YajC PF02699.15 KIK54256.1 - 0.16 11.9 7.8 18 5.3 0.0 5.4 3 3 3 6 6 6 0 Preprotein translocase subunit TrmK PF04816.12 KIK54256.1 - 0.71 9.4 8.9 1.5 8.3 1.6 2.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase CholecysA-Rec_N PF09193.10 KIK54256.1 - 8.6 6.5 6.6 59 3.8 0.1 4.0 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal Pro_isomerase PF00160.21 KIK54261.1 - 2e-10 41.2 0.0 2.1e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 KIK54262.1 - 4.5e-07 30.3 0.0 5.1e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NACHT PF05729.12 KIK54268.1 - 0.003 17.5 1.1 0.0036 17.2 0.3 1.5 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 KIK54268.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ank_2 PF12796.7 KIK54269.1 - 5.3e-51 171.1 31.2 3.1e-12 46.9 0.7 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54269.1 - 8.3e-32 109.2 2.4 2.6e-05 24.7 0.0 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54269.1 - 4.8e-27 91.0 3.6 0.028 14.9 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KIK54269.1 - 1.9e-24 85.0 14.4 0.021 15.3 0.1 7.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KIK54269.1 - 2.3e-15 56.5 10.0 0.029 14.7 0.1 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) YajC PF02699.15 KIK54269.1 - 2.4e-05 24.1 3.1 3.1 7.7 0.0 5.4 1 1 5 6 6 6 1 Preprotein translocase subunit UNC-93 PF05978.16 KIK54269.1 - 0.0001 22.1 3.0 17 5.1 0.0 4.9 2 2 3 5 5 5 0 Ion channel regulatory protein UNC-93 RTC4 PF14474.6 KIK54269.1 - 0.00065 19.9 5.9 3.4 7.9 0.0 4.0 3 1 1 4 4 4 2 RTC4-like domain NdhO PF11910.8 KIK54269.1 - 0.042 14.0 0.7 55 4.0 0.0 4.3 3 2 3 6 6 6 0 Cyanobacterial and plant NDH-1 subunit O AlaE PF06610.13 KIK54269.1 - 0.068 13.2 0.2 0.65 10.0 0.0 2.4 3 0 0 3 3 3 0 L-alanine exporter DUF3710 PF12502.8 KIK54269.1 - 0.076 12.7 5.1 6.8 6.3 0.2 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3710) DUF3396 PF11876.8 KIK54269.1 - 0.42 10.0 3.8 20 4.6 0.1 3.8 1 1 5 6 6 6 0 Protein of unknown function (DUF3396) HicA_toxin PF07927.12 KIK54269.1 - 1 9.5 4.0 1.3e+02 2.7 0.0 4.7 6 0 0 6 6 6 0 HicA toxin of bacterial toxin-antitoxin, ApbA PF02558.16 KIK54269.1 - 2 8.0 13.0 0.76 9.4 0.1 4.2 2 1 2 5 5 5 0 Ketopantoate reductase PanE/ApbA gag_pre-integrs PF13976.6 KIK54270.1 - 0.00045 20.0 0.0 0.00063 19.6 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain HMMR_N PF15905.5 KIK54271.1 - 0.00022 20.8 4.3 0.00031 20.3 4.3 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK54271.1 - 0.0071 15.3 7.6 0.01 14.8 7.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6_N PF17675.1 KIK54271.1 - 0.011 16.2 8.6 0.023 15.2 8.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region LRS4 PF10422.9 KIK54271.1 - 0.023 14.3 3.6 0.037 13.6 3.6 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fib_alpha PF08702.10 KIK54271.1 - 0.027 14.7 0.9 0.069 13.3 0.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KIK54271.1 - 0.047 14.0 8.9 0.076 13.4 3.8 2.6 1 1 2 3 3 3 0 Csm1 N-terminal domain Fez1 PF06818.15 KIK54271.1 - 0.12 12.8 7.0 0.18 12.3 7.0 1.2 1 0 0 1 1 1 0 Fez1 Fungal_TACC PF12709.7 KIK54271.1 - 0.18 12.2 2.0 2.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins GAS PF13851.6 KIK54271.1 - 0.31 10.4 7.0 0.58 9.5 2.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 KIK54271.1 - 0.33 10.6 7.3 1.1 8.9 7.2 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 KIK54271.1 - 0.39 10.4 4.0 2.1 8.1 4.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 KIK54271.1 - 0.4 10.7 11.2 3 7.9 8.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_23 PF13476.6 KIK54271.1 - 0.63 10.5 3.1 0.89 10.0 3.1 1.2 1 0 0 1 1 1 0 AAA domain ADIP PF11559.8 KIK54271.1 - 1.2 9.3 7.4 5.2 7.1 7.4 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 KIK54271.1 - 1.2 9.2 7.2 0.61 10.1 0.2 2.6 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Med9 PF07544.13 KIK54271.1 - 1.4 9.1 6.2 8.5 6.5 0.1 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ERM PF00769.19 KIK54271.1 - 1.9 8.3 10.3 3.1 7.5 10.3 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PKcGMP_CC PF16808.5 KIK54271.1 - 3.1 7.7 8.0 32 4.5 0.0 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 KIK54271.1 - 3.5 7.8 10.8 16 5.7 10.8 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 KIK54271.1 - 3.5 8.1 6.9 6.9 7.1 3.7 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Retrotrans_gag PF03732.17 KIK54273.1 - 9.7e-07 29.0 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1181 PF06680.11 KIK54274.1 - 0.18 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) NACHT PF05729.12 KIK54275.1 - 1.2e-10 41.6 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KIK54275.1 - 0.027 14.5 0.0 0.74 9.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK54275.1 - 0.057 12.6 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KIK54275.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KIK54275.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KIK54275.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 KIK54275.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain MCD PF05292.11 KIK54276.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain LEDGF PF11467.8 KIK54277.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Ank_2 PF12796.7 KIK54279.1 - 3.5e-27 94.8 30.5 4.5e-10 40.0 4.1 4.2 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54279.1 - 2.9e-22 78.7 7.6 9.2e-07 29.3 0.3 6.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54279.1 - 9.9e-20 68.6 13.5 0.0073 16.7 0.2 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KIK54279.1 - 3.8e-17 61.9 24.6 0.012 16.0 0.3 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KIK54279.1 - 7.3e-10 38.9 16.6 0.021 15.1 1.8 6.4 3 2 2 6 6 6 3 Ankyrin repeats (many copies) DUF1843 PF08898.10 KIK54279.1 - 0.01 16.3 10.4 3.3 8.3 0.1 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) FLgD_tudor PF13861.6 KIK54279.1 - 0.027 14.7 0.0 1.2 9.4 0.0 3.4 2 1 0 2 2 2 0 FlgD Tudor-like domain SWIRM-assoc_2 PF16496.5 KIK54282.1 - 0.042 12.7 0.4 0.048 12.5 0.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF1381 PF07129.11 KIK54282.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) RVP_2 PF08284.11 KIK54287.1 - 0.031 14.0 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK54288.1 - 0.00048 20.7 0.0 0.0013 19.4 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK54288.1 - 0.0016 19.0 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 KIK54295.1 - 1.7e-08 34.6 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Ank_2 PF12796.7 KIK54297.1 - 2.8e-40 136.8 23.9 2.7e-11 43.9 0.6 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54297.1 - 2.2e-35 120.6 2.0 0.0001 22.8 0.0 7.3 4 1 4 8 8 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54297.1 - 1.8e-22 77.0 13.8 0.022 15.2 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KIK54297.1 - 5.5e-22 77.2 18.0 0.025 15.0 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KIK54297.1 - 6.8e-18 64.5 9.1 4.8e-05 23.6 0.1 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 KIK54297.1 - 0.00023 21.0 0.0 3.2 7.8 0.0 4.1 1 1 4 5 5 5 1 Domain of unknown function (DUF3447) Shigella_OspC PF06128.11 KIK54297.1 - 0.006 16.4 4.9 12 5.5 0.1 4.7 2 1 3 5 5 5 1 Shigella flexneri OspC protein Exo_endo_phos_2 PF14529.6 KIK54297.1 - 0.0062 16.4 0.1 3.7 7.4 0.0 3.7 1 1 3 4 4 4 1 Endonuclease-reverse transcriptase BNIP3 PF06553.12 KIK54297.1 - 0.046 13.4 0.1 49 3.5 0.0 3.5 3 1 0 3 3 3 0 BNIP3 TOBE PF03459.17 KIK54297.1 - 0.12 12.7 1.0 1.3e+02 3.0 0.0 4.7 5 0 0 5 5 5 0 TOBE domain SCHIP-1 PF10148.9 KIK54297.1 - 0.24 11.0 1.5 73 2.9 0.1 4.1 4 1 1 5 5 5 0 Schwannomin-interacting protein 1 Toprim_C_rpt PF13368.6 KIK54297.1 - 0.31 11.1 2.5 83 3.3 0.0 4.3 5 0 0 5 5 5 0 Topoisomerase C-terminal repeat DUF1843 PF08898.10 KIK54297.1 - 0.49 10.9 4.9 67 4.1 0.0 4.6 6 0 0 6 6 4 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 KIK54299.1 - 9.7e-30 103.0 19.9 1.5e-11 44.7 3.5 4.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54299.1 - 1.4e-26 92.5 9.2 1.3e-07 32.0 0.1 6.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54299.1 - 3.5e-23 79.2 15.0 0.0044 17.4 0.1 9.1 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 KIK54299.1 - 2.1e-22 78.5 30.1 0.01 16.3 0.2 9.1 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KIK54299.1 - 5.6e-07 29.7 16.5 0.092 13.1 0.3 6.2 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Mic1 PF07035.12 KIK54299.1 - 0.0007 19.3 0.2 2.3 7.9 0.0 3.6 3 2 1 4 4 4 2 Colon cancer-associated protein Mic1-like End_beta_barrel PF12195.8 KIK54299.1 - 0.058 13.3 2.5 10 6.2 0.2 3.2 2 2 1 3 3 3 0 Beta barrel domain of bacteriophage endosialidase DUF188 PF02639.14 KIK54299.1 - 0.17 11.6 0.6 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF3344 PF11824.8 KIK54299.1 - 0.2 11.2 3.9 1.7 8.2 2.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3344) RNase_PH_C PF03725.15 KIK54299.1 - 0.54 10.3 4.2 67 3.6 0.9 4.2 2 2 1 3 3 3 0 3' exoribonuclease family, domain 2 TrbI PF03743.14 KIK54299.1 - 0.72 9.7 6.5 4.4 7.1 0.1 2.8 2 1 0 2 2 2 0 Bacterial conjugation TrbI-like protein NACHT PF05729.12 KIK54300.1 - 3.8e-10 39.9 0.0 5.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK54300.1 - 0.009 16.3 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK54300.1 - 0.0096 15.2 0.0 0.067 12.4 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK54300.1 - 0.018 15.1 0.0 0.35 10.9 0.0 2.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK54300.1 - 0.024 13.8 0.0 0.13 11.4 0.0 2.1 2 1 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KIK54300.1 - 0.025 15.0 0.0 0.052 13.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KIK54300.1 - 0.029 13.6 1.4 0.049 12.9 0.1 1.8 2 1 0 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 KIK54300.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.6 KIK54300.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KIK54300.1 - 0.12 12.4 0.5 0.3 11.1 0.1 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2990 PF11693.8 KIK54304.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Vpu PF00558.19 KIK54305.1 - 0.16 11.8 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Vpu protein DUF3243 PF11588.8 KIK54307.1 - 0.057 13.7 0.3 0.14 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) DUF2218 PF09981.9 KIK54307.1 - 0.063 13.7 2.4 1.1 9.6 2.3 2.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) ANAPC2 PF08672.11 KIK54307.1 - 0.11 13.0 1.4 8.2 7.0 0.2 2.8 1 1 1 2 2 2 0 Anaphase promoting complex (APC) subunit 2 DASH_Spc34 PF08657.10 KIK54307.1 - 0.12 12.1 10.2 39 3.9 9.7 2.9 1 1 0 1 1 1 0 DASH complex subunit Spc34 Vac_ImportDeg PF09783.9 KIK54307.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Vacuolar import and degradation protein YabA PF06156.13 KIK54307.1 - 0.15 12.8 19.8 0.69 10.6 3.4 3.9 1 1 2 3 3 3 0 Initiation control protein YabA DUF4899 PF16240.5 KIK54307.1 - 0.27 10.4 1.9 0.44 9.7 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4899) ZapB PF06005.12 KIK54307.1 - 0.34 11.4 23.9 9.8 6.7 3.6 4.4 1 1 2 3 3 3 0 Cell division protein ZapB SIKE PF05769.11 KIK54307.1 - 0.57 10.1 17.5 0.55 10.1 5.2 3.2 1 1 2 3 3 3 0 SIKE family bZIP_2 PF07716.15 KIK54307.1 - 0.99 9.5 18.6 5.3 7.2 0.1 5.2 4 1 1 5 5 5 0 Basic region leucine zipper bZIP_1 PF00170.21 KIK54307.1 - 1.2 9.3 13.8 2.3 8.4 0.4 4.4 3 1 1 4 4 4 0 bZIP transcription factor Mce4_CUP1 PF11887.8 KIK54307.1 - 3.6 7.0 8.1 0.69 9.3 0.2 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative TMF_TATA_bd PF12325.8 KIK54307.1 - 6.2 7.1 16.0 19 5.5 3.9 3.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NTNH_C PF08470.10 KIK54308.1 - 0.025 14.5 0.3 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal Meth_synt_2 PF01717.18 KIK54308.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain C1_2 PF03107.16 KIK54308.1 - 1.6 9.1 5.0 4.9 7.5 0.7 2.4 2 0 0 2 2 2 0 C1 domain Skp1_POZ PF03931.15 KIK54310.1 - 2.5e-17 62.8 0.0 4.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KIK54310.1 - 4.3e-06 26.7 0.6 8.5e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain F-box PF00646.33 KIK54312.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF4724 PF15852.5 KIK54313.1 - 0.089 13.3 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) PLDc_N PF13396.6 KIK54315.1 - 0.24 11.4 1.0 0.46 10.5 1.0 1.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal F-box-like PF12937.7 KIK54317.1 - 0.039 13.9 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIK54322.1 - 5.1e-05 23.1 0.3 0.00014 21.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK54322.1 - 0.046 13.6 1.9 0.087 12.7 0.3 2.2 2 0 0 2 2 2 0 F-box PAN_1 PF00024.26 KIK54323.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PAN domain adh_short PF00106.25 KIK54325.1 - 8.9e-33 113.4 0.6 3.6e-32 111.4 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54325.1 - 7.6e-26 91.1 2.2 3.6e-24 85.6 2.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK54325.1 - 1.3e-06 28.5 0.6 2.1e-06 27.8 0.1 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KIK54325.1 - 0.00042 19.8 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 KIK54325.1 - 0.035 14.4 0.2 0.088 13.1 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PBP3 PF18056.1 KIK54325.1 - 0.12 12.5 0.1 0.33 11.1 0.1 1.7 2 0 0 2 2 2 0 Penicillin Binding Protein 3 Domain adh_short PF00106.25 KIK54326.1 - 3.9e-44 150.4 0.2 6.2e-44 149.8 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54326.1 - 2.8e-33 115.5 0.2 5.3e-33 114.5 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK54326.1 - 1.1e-12 48.2 0.2 2.7e-12 47.0 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK54326.1 - 3.4e-07 30.0 0.4 5.2e-07 29.4 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK54326.1 - 0.0015 18.0 0.5 0.04 13.3 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIK54326.1 - 0.0015 17.9 0.2 0.0043 16.5 0.2 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KIK54326.1 - 0.0027 17.6 0.2 0.0046 16.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK54326.1 - 0.0055 17.0 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glyco_transf_4 PF13439.6 KIK54326.1 - 0.011 15.8 0.1 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 RmlD_sub_bind PF04321.17 KIK54326.1 - 0.015 14.4 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KIK54326.1 - 0.026 14.1 0.2 0.039 13.5 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_trans_4_4 PF13579.6 KIK54326.1 - 0.029 14.8 0.0 5.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KIK54326.1 - 0.053 13.6 0.1 6.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Polysacc_synt_2 PF02719.15 KIK54326.1 - 0.054 12.6 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 KIK54327.1 - 3.2e-06 26.9 0.6 1e-05 25.3 0.6 1.9 1 1 0 1 1 1 1 F-box-like Ntox28 PF15605.6 KIK54327.1 - 0.15 12.4 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 28 DUF3445 PF11927.8 KIK54329.1 - 1.1e-61 208.4 0.0 1.4e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3433 PF11915.8 KIK54330.1 - 1.9e-18 66.7 10.7 3.5e-15 56.2 1.6 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DUF4079 PF13301.6 KIK54330.1 - 0.0068 16.6 0.0 2 8.5 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) MARVEL PF01284.23 KIK54330.1 - 0.01 15.8 3.1 0.1 12.6 3.1 2.6 1 1 0 1 1 1 0 Membrane-associating domain DUF485 PF04341.12 KIK54330.1 - 1.9 8.5 8.0 6.4 6.8 4.9 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ERG4_ERG24 PF01222.17 KIK54331.1 - 4.7e-98 328.8 23.1 5.8e-61 206.6 13.4 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK54331.1 - 2.1e-05 24.1 2.7 4.6e-05 23.0 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK54331.1 - 0.00035 20.9 1.0 0.00096 19.5 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Iron_permease PF04120.12 KIK54331.1 - 1.1 9.0 2.6 0.57 10.0 0.1 1.8 2 0 0 2 2 2 0 Low affinity iron permease p450 PF00067.22 KIK54332.1 - 1.4e-58 198.8 0.0 6.5e-58 196.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF1910 PF08928.10 KIK54332.1 - 0.17 11.9 0.3 1.1 9.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) PIF1 PF05970.14 KIK54334.1 - 0.2 10.8 0.2 0.43 9.7 0.2 1.5 2 0 0 2 2 2 0 PIF1-like helicase PhrC_PhrF PF11131.8 KIK54336.1 - 0.15 11.7 1.8 0.31 10.7 1.8 1.5 1 0 0 1 1 1 0 Rap-phr extracellular signalling GCK PF07802.11 KIK54337.1 - 0.032 14.6 0.4 0.19 12.2 0.1 2.4 2 1 0 2 2 2 0 GCK domain PIF1 PF05970.14 KIK54340.1 - 1.1e-07 31.4 0.0 1.3e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK54340.1 - 4.1e-07 29.9 0.0 4.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK54340.1 - 1.4e-05 25.5 0.0 2.3e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KIK54340.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Helicase Viral_helicase1 PF01443.18 KIK54340.1 - 0.054 13.2 0.0 0.078 12.7 0.0 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIK54340.1 - 0.078 13.3 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Guanylate_kin PF00625.21 KIK54340.1 - 0.091 12.4 0.0 0.25 11.0 0.0 1.6 1 1 1 2 2 2 0 Guanylate kinase IIGP PF05049.13 KIK54340.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRP54 PF00448.22 KIK54340.1 - 0.16 11.6 0.0 3.3 7.3 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FLYWCH PF04500.16 KIK54342.1 - 0.0088 16.1 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 FLYWCH zinc finger domain Abhydrolase_4 PF08386.10 KIK54344.1 - 0.15 12.2 0.1 1.1 9.4 0.0 2.1 2 1 0 2 2 2 0 TAP-like protein DDE_3 PF13358.6 KIK54345.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease AdoMet_MTase PF07757.13 KIK54346.1 - 0.082 13.3 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase p450 PF00067.22 KIK54347.1 - 9.5e-59 199.3 0.0 1.1e-56 192.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Spore_YtrH PF14034.6 KIK54347.1 - 0.01 16.0 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 0 Sporulation protein YtrH TetR_C_27 PF17935.1 KIK54347.1 - 0.2 11.7 0.3 0.42 10.7 0.3 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ank_4 PF13637.6 KIK54354.1 - 2.4e-24 85.4 3.4 1e-09 38.7 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK54354.1 - 2e-19 69.9 1.2 6.7e-09 36.2 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK54354.1 - 2e-17 63.0 1.3 1.7e-11 44.1 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK54354.1 - 3e-16 59.0 3.9 7e-06 26.3 0.2 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KIK54354.1 - 3.1e-15 54.7 0.1 2.6e-06 27.3 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat DUF1110 PF06533.12 KIK54354.1 - 0.14 12.1 0.4 16 5.4 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1110) ETRAMP PF09716.10 KIK54355.1 - 0.032 14.3 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SieB PF14163.6 KIK54355.1 - 0.15 11.5 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B CGI-121 PF08617.10 KIK54357.1 - 1.7e-47 161.5 0.1 2e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 KIK54358.1 - 5.8e-27 93.7 0.0 1.9e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin PF00085.20 KIK54359.1 - 2.3e-07 30.7 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin CGI-121 PF08617.10 KIK54362.1 - 2.9e-47 160.8 0.0 3.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 KIK54363.1 - 2.6e-51 171.9 0.0 7.1e-27 93.4 0.0 2.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KIK54363.1 - 8.8e-11 42.0 0.0 1e-07 32.1 0.0 3.6 3 1 1 4 4 4 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KIK54363.1 - 8.9e-07 28.5 0.0 0.0078 15.6 0.0 4.1 4 1 0 4 4 4 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KIK54363.1 - 8.8e-05 22.9 0.9 0.0058 17.1 0.1 3.3 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK54363.1 - 0.00032 21.0 0.1 0.33 11.3 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 KIK54363.1 - 0.0039 17.0 0.0 0.052 13.4 0.0 2.5 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KIK54363.1 - 0.013 15.5 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain adh_short PF00106.25 KIK54364.1 - 7.4e-10 38.6 0.0 2.3e-05 24.0 0.0 3.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54364.1 - 0.029 13.9 0.0 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.24 KIK54365.1 - 4.5e-123 411.5 24.6 5.2e-123 411.2 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK54365.1 - 7.4e-23 81.0 33.3 1e-13 51.0 11.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIK54365.1 - 2.8 8.2 11.4 0.047 13.9 3.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Abhydrolase_1 PF00561.20 KIK54366.1 - 2.2e-05 24.3 0.1 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK54366.1 - 0.074 12.3 0.1 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 KIK54367.1 - 9.3e-57 192.8 0.0 1.6e-56 192.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIK54367.1 - 0.009 16.5 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK54367.1 - 0.01 16.3 0.0 0.03 14.7 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIK54367.1 - 0.014 14.5 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIK54367.1 - 0.046 12.6 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK54367.1 - 0.09 12.0 0.0 0.34 10.1 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK54367.1 - 0.1 12.2 0.2 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK54367.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KIK54367.1 - 0.2 10.3 0.1 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein PPR PF01535.20 KIK54368.1 - 0.0028 17.8 0.8 12 6.4 0.0 4.4 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 KIK54368.1 - 0.0031 17.7 0.0 5 7.4 0.0 4.2 3 1 0 3 3 3 2 PPR repeat family Ank_4 PF13637.6 KIK54370.1 - 3.4e-22 78.5 0.2 1e-11 45.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK54370.1 - 7.4e-14 52.1 0.2 3.5e-13 49.9 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK54370.1 - 2.9e-13 49.8 0.7 3.1e-10 40.1 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54370.1 - 3.1e-13 48.6 0.1 1.1e-06 28.4 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIK54370.1 - 4.9e-11 42.6 0.2 1.4e-06 28.4 0.1 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KIK54371.1 - 2.6e-45 152.9 12.3 4.6e-15 56.0 0.6 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54371.1 - 4.8e-39 132.3 21.5 2e-09 37.8 0.1 6.4 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54371.1 - 1.9e-38 126.1 10.5 4.8e-05 23.4 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KIK54371.1 - 2.4e-37 126.5 13.9 6.2e-12 45.5 0.3 7.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KIK54371.1 - 1.1e-32 111.0 20.2 1.3e-05 25.4 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat HicA_toxin PF07927.12 KIK54372.1 - 0.16 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Ig_mannosidase PF17753.1 KIK54373.1 - 5.6e-15 54.9 0.9 1.3e-14 53.7 0.1 2.2 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 KIK54373.1 - 5.1e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIK54373.1 - 0.00049 20.7 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Zip PF02535.22 KIK54374.1 - 4.6e-59 200.3 11.6 5.3e-59 200.1 11.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter VKOR PF07884.14 KIK54374.1 - 4.7 7.4 16.3 0.19 11.9 0.5 3.4 2 2 1 3 3 3 0 Vitamin K epoxide reductase family Pkinase PF00069.25 KIK54375.1 - 1.2e-08 34.7 0.0 9.3e-07 28.5 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54375.1 - 0.001 18.4 0.1 0.0036 16.6 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KIK54378.1 - 2.2e-10 40.4 0.0 5.4e-08 32.5 0.0 2.5 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54378.1 - 0.00037 19.9 0.1 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK54378.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MIF4G_like_2 PF09090.11 KIK54380.1 - 2e-72 243.9 0.0 3.3e-72 243.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KIK54380.1 - 4.1e-61 206.1 0.1 1.8e-60 204.0 0.0 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KIK54380.1 - 0.016 14.9 0.0 0.077 12.6 0.0 2.1 2 0 0 2 2 2 0 MIF4G domain Myelin_PLP PF01275.19 KIK54381.1 - 5.5 6.8 10.3 0.14 12.0 3.7 1.6 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) Pil1 PF13805.6 KIK54382.1 - 6.9e-21 74.9 0.5 1.2e-20 74.2 0.5 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 Pentapeptide_2 PF01469.18 KIK54382.1 - 0.018 14.9 1.4 0.018 14.9 1.4 2.1 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) T3SSipB PF16535.5 KIK54382.1 - 0.02 15.4 2.9 0.032 14.7 2.0 1.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF773 PF05600.12 KIK54382.1 - 0.072 11.8 0.5 0.11 11.2 0.5 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 IFT57 PF10498.9 KIK54382.1 - 0.11 11.4 1.7 0.17 10.9 1.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 APG6_N PF17675.1 KIK54382.1 - 0.13 12.8 4.1 0.24 11.9 4.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Fez1 PF06818.15 KIK54382.1 - 0.14 12.6 1.1 0.26 11.7 1.1 1.3 1 0 0 1 1 1 0 Fez1 DHR10 PF18595.1 KIK54382.1 - 0.19 11.8 6.1 0.096 12.7 3.3 2.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 KIK54382.1 - 0.37 11.5 1.9 0.7 10.7 1.9 1.3 1 0 0 1 1 1 0 Occludin homology domain UPF0242 PF06785.11 KIK54382.1 - 0.44 10.6 2.4 0.68 10.0 2.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 KIK54382.1 - 1.7 8.8 5.0 4 7.6 5.0 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 FlgN PF05130.12 KIK54382.1 - 7.3 7.1 7.0 9.8 6.7 4.3 2.1 1 1 1 2 2 2 0 FlgN protein Nucleos_tra2_C PF07662.13 KIK54383.1 - 5.3e-62 209.3 9.2 5.3e-62 209.3 9.2 2.6 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KIK54383.1 - 1.5e-15 57.6 4.4 1.5e-15 57.6 4.4 4.4 4 2 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus DUF2254 PF10011.9 KIK54385.1 - 0.23 10.3 2.8 0.35 9.7 2.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Pkinase PF00069.25 KIK54388.1 - 1.1e-06 28.2 0.0 2.5e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54388.1 - 0.0022 17.3 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK54388.1 - 0.075 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LPD22 PF18834.1 KIK54389.1 - 0.0078 16.4 0.2 0.025 14.8 0.2 1.8 1 0 0 1 1 1 1 Large polyvalent protein associated domain 22 Exonuc_VII_S PF02609.16 KIK54389.1 - 0.078 13.0 0.3 0.59 10.2 0.0 2.5 3 0 0 3 3 3 0 Exonuclease VII small subunit Sad1_UNC PF07738.13 KIK54389.1 - 0.13 12.2 0.0 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Pkinase PF00069.25 KIK54390.1 - 1.3e-07 31.2 0.0 1.5e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54390.1 - 0.0091 15.3 0.2 0.023 14.0 0.1 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase UAA PF08449.11 KIK54391.1 - 4.2e-67 226.5 14.3 2.3e-65 220.8 14.3 2.9 1 1 0 1 1 1 1 UAA transporter family Tetraspanin PF00335.20 KIK54391.1 - 0.039 13.6 1.2 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetraspanin family Cyclin_N PF00134.23 KIK54392.1 - 6.5e-11 42.1 0.4 1e-10 41.4 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK54392.1 - 3.3e-08 34.1 0.2 4.7e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 Cyclin ketoacyl-synt PF00109.26 KIK54393.1 - 1.2e-50 172.4 0.1 2.4e-50 171.5 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK54393.1 - 1.1e-35 123.6 0.1 2e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KIK54393.1 - 4.4e-31 108.2 0.0 8.1e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KIK54393.1 - 7.8e-29 100.9 0.0 1.7e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KIK54393.1 - 2.7e-27 95.1 0.0 5.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KIK54393.1 - 5.8e-13 49.5 0.0 1.2e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 KIK54393.1 - 3.8e-12 46.7 0.0 9.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIK54393.1 - 0.00021 21.5 0.3 0.00053 20.3 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KIK54393.1 - 0.00025 20.5 0.9 0.00059 19.3 0.9 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KIK54393.1 - 0.0015 18.4 0.5 0.0055 16.5 0.5 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 KIK54394.1 - 2.4e-11 43.7 0.0 8.2e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK54394.1 - 3.1e-06 27.0 0.2 0.001 18.9 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK54394.1 - 0.0002 22.4 0.0 0.00045 21.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 KIK54395.1 - 8.7e-17 61.1 53.2 1.3e-11 44.0 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK54395.1 - 0.33 9.8 36.4 0.88 8.4 8.1 3.2 3 0 0 3 3 3 0 Sugar (and other) transporter Ribonuc_L-PSP PF01042.21 KIK54396.1 - 2.5e-19 69.5 0.0 3e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box-like PF12937.7 KIK54398.1 - 0.00042 20.1 0.2 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like Nop PF01798.18 KIK54399.1 - 8.4e-85 283.9 0.3 8.4e-85 283.9 0.3 2.3 2 1 1 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIK54399.1 - 3.2e-08 33.8 0.2 3.2e-08 33.8 0.2 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Peptidase_S10 PF00450.22 KIK54400.1 - 3e-107 359.6 0.0 3.7e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UPAR_LY6 PF00021.21 KIK54400.1 - 0.033 14.9 0.7 0.087 13.5 0.7 1.7 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Abhydrolase_6 PF12697.7 KIK54400.1 - 0.048 14.2 0.0 1.3 9.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family gp45-slide_C PF09116.10 KIK54400.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Ferritin_2 PF13668.6 KIK54401.1 - 5.6e-35 120.5 4.4 8.6e-35 119.9 4.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain EAF PF09816.9 KIK54402.1 - 2.4e-19 69.6 0.0 5.4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Endonuc_Holl PF10107.9 KIK54402.1 - 0.0058 16.5 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase Glyco_hydro_28 PF00295.17 KIK54403.1 - 3.2e-52 177.6 15.6 4.3e-52 177.2 15.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1565 PF07602.11 KIK54403.1 - 3.3e-05 23.4 8.4 4.7e-05 22.8 8.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) HET PF06985.11 KIK54404.1 - 9e-16 58.5 0.1 1.5e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_28 PF00295.17 KIK54405.1 - 2.7e-53 181.1 14.2 2.7e-53 181.1 14.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 NosD PF05048.13 KIK54405.1 - 1.2e-06 28.0 5.5 2.5e-06 27.0 5.5 1.6 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KIK54405.1 - 2e-05 24.0 6.7 2e-05 24.0 6.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) KH_8 PF17903.1 KIK54407.1 - 3.7e-33 113.5 0.1 7.9e-32 109.2 0.0 2.5 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KIK54407.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIK54407.1 - 0.042 13.7 0.3 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 KH domain NCBP3 PF10309.9 KIK54408.1 - 1.1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KIK54408.1 - 9e-05 23.0 55.9 0.00035 21.1 17.9 4.6 4 1 0 4 4 4 3 C-terminal duplication domain of Friend of PRMT1 adh_short_C2 PF13561.6 KIK54410.1 - 5.2e-60 202.9 0.6 6e-60 202.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK54410.1 - 1.4e-47 161.7 0.6 1.9e-47 161.3 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK54410.1 - 1.8e-06 28.0 0.1 2.7e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 KR domain SBBP PF06739.11 KIK54410.1 - 0.017 15.1 0.4 0.33 11.0 0.0 2.8 2 0 0 2 2 2 0 Beta-propeller repeat IreB PF06135.12 KIK54410.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 IreB regulatory phosphoprotein adh_short_C2 PF13561.6 KIK54411.1 - 1.2e-59 201.7 0.5 1.4e-59 201.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK54411.1 - 3.2e-47 160.5 0.2 4.3e-47 160.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK54411.1 - 2e-06 27.9 0.1 2.6e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 KR domain SBBP PF06739.11 KIK54411.1 - 0.02 14.9 0.7 0.33 11.0 0.0 2.8 2 0 0 2 2 2 0 Beta-propeller repeat IreB PF06135.12 KIK54411.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 IreB regulatory phosphoprotein adh_short_C2 PF13561.6 KIK54412.1 - 7.7e-60 202.4 0.3 8.9e-60 202.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK54412.1 - 1.2e-47 161.9 0.1 1.6e-47 161.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK54412.1 - 3.8e-06 26.9 0.1 5.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 KR domain SBBP PF06739.11 KIK54412.1 - 0.02 14.9 0.7 0.33 11.0 0.0 2.9 2 0 0 2 2 2 0 Beta-propeller repeat IreB PF06135.12 KIK54412.1 - 0.17 12.1 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 IreB regulatory phosphoprotein CAF1-p150_C2 PF15539.6 KIK54413.1 - 0.025 14.0 0.2 0.037 13.5 0.2 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF1A PF12253.8 KIK54414.1 - 6 7.1 8.4 2.7 8.3 2.2 2.7 1 1 1 2 2 2 0 Chromatin assembly factor 1 subunit A ERM PF00769.19 KIK54415.1 - 0.00095 19.1 41.2 0.00095 19.1 41.2 2.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Borrelia_P83 PF05262.11 KIK54415.1 - 2.6 6.4 42.5 21 3.5 42.5 2.1 1 1 0 1 1 1 0 Borrelia P83/100 protein DDE_1 PF03184.19 KIK54418.1 - 5.6e-06 26.1 0.0 6.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sushi_2 PF09014.10 KIK54418.1 - 0.068 13.1 2.2 0.18 11.7 0.5 2.0 1 1 1 2 2 2 0 Beta-2-glycoprotein-1 fifth domain DUF1122 PF06557.11 KIK54418.1 - 0.13 11.7 0.2 2.7 7.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1122) Ras PF00071.22 KIK54420.1 - 1.9e-27 95.9 0.0 2.1e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KIK54420.1 - 0.0016 18.4 0.1 0.0027 17.6 0.1 1.3 1 1 0 1 1 1 1 RsgA GTPase ImcF-related_N PF14331.6 KIK54420.1 - 0.0054 16.1 0.1 0.0068 15.8 0.1 1.1 1 0 0 1 1 1 1 ImcF-related N-terminal domain TetR_C_12 PF16914.5 KIK54420.1 - 0.088 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal NAC PF01849.18 KIK54420.1 - 0.18 11.8 0.1 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 NAC domain Pkinase_Tyr PF07714.17 KIK54421.1 - 2.2e-38 132.0 0.0 2.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK54421.1 - 7.4e-28 97.6 0.0 1.2e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM_bind PF01803.16 KIK54423.1 - 5.1e-61 206.3 0.0 2.2e-60 204.2 0.0 2.0 2 0 0 2 2 2 1 LIM-domain binding protein S4 PF01479.25 KIK54424.1 - 1.3e-11 44.0 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KIK54424.1 - 1.8e-11 44.8 0.5 2.5e-11 44.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain NACHT PF05729.12 KIK54425.1 - 0.00014 21.8 0.2 0.00025 21.0 0.2 1.4 1 0 0 1 1 1 1 NACHT domain NAD_binding_10 PF13460.6 KIK54426.1 - 1.2e-09 38.3 0.0 4.3e-05 23.5 0.0 2.3 2 1 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KIK54426.1 - 0.00054 19.5 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54426.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 KIK54426.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Heme_oxygenase PF01126.20 KIK54429.1 - 0.0052 16.6 0.1 0.0088 15.8 0.1 1.3 1 0 0 1 1 1 1 Heme oxygenase Fez1 PF06818.15 KIK54429.1 - 0.016 15.7 6.9 0.032 14.7 6.8 1.5 1 1 0 1 1 1 0 Fez1 YopE PF03545.13 KIK54429.1 - 0.023 14.9 1.6 5.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) DUF498 PF04430.14 KIK54429.1 - 0.045 13.8 0.0 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Trs65 PF12735.7 KIK54429.1 - 0.081 12.3 0.5 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF4407 PF14362.6 KIK54429.1 - 0.18 11.1 2.8 0.91 8.8 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SLX9 PF15341.6 KIK54429.1 - 0.19 12.1 3.5 0.08 13.3 1.0 1.7 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 ATG16 PF08614.11 KIK54429.1 - 0.25 11.5 16.7 3.4 7.8 9.9 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIK54429.1 - 2.4 8.7 13.1 0.19 12.3 6.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KIK54429.1 - 8.2 6.5 16.5 0.16 12.0 5.1 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltransf_23 PF13489.6 KIK54430.1 - 1.3e-10 41.4 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK54430.1 - 9.9e-10 39.0 0.0 1.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK54430.1 - 1.8e-06 27.8 0.0 8.2e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK54430.1 - 1.7e-05 24.3 0.0 0.00034 20.0 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK54430.1 - 2.9e-05 24.6 0.0 6.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK54430.1 - 0.0067 17.2 0.0 0.035 14.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain ArAE_2_N PF10337.9 KIK54431.1 - 2.3e-74 251.1 0.2 3.8e-74 250.4 0.2 1.3 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KIK54431.1 - 5e-39 134.5 0.2 1.1e-35 123.6 0.0 3.2 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KIK54431.1 - 7.1e-11 42.3 14.6 7.1e-11 42.3 14.6 3.5 3 0 0 3 3 3 1 Fusaric acid resistance protein-like PSDC PF12588.8 KIK54432.1 - 2e-50 170.4 0.1 2.9e-50 169.9 0.1 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KIK54432.1 - 4.4e-38 130.9 0.0 6e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KIK54433.1 - 2.1e-52 176.8 0.1 3.3e-52 176.2 0.1 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KIK54433.1 - 7.4e-38 130.1 0.0 9.4e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 KIK54433.1 - 0.12 12.2 0.3 1.1 9.1 0.2 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme Glyco_hydro_44 PF12891.7 KIK54434.1 - 3e-59 200.8 1.7 5.5e-59 200.0 1.7 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 44 PSDC PF12588.8 KIK54435.1 - 1.3e-51 174.3 0.1 2e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KIK54435.1 - 2.7e-37 128.3 0.0 3.4e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 KIK54435.1 - 0.1 12.4 0.2 1.1 9.1 0.2 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme PSDC PF12588.8 KIK54436.1 - 6.1e-46 155.9 0.0 9.1e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KIK54436.1 - 8.9e-37 126.6 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase F-box-like PF12937.7 KIK54437.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like zf_Hakai PF18408.1 KIK54437.1 - 1.4 8.7 3.3 0.71 9.6 0.3 1.9 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain Pkinase PF00069.25 KIK54442.1 - 1.4e-49 168.9 0.0 1.7e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54442.1 - 4.4e-25 88.4 0.0 5.2e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KIK54442.1 - 0.0051 16.5 0.0 0.3 10.7 0.0 2.1 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Ala_racemase_N PF01168.20 KIK54443.1 - 1.6e-18 67.1 0.0 2.8e-12 46.7 0.0 3.0 1 1 1 2 2 2 2 Alanine racemase, N-terminal domain DUF4653 PF15546.6 KIK54443.1 - 0.03 13.9 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) HalX PF08663.10 KIK54443.1 - 0.38 11.1 5.2 1.7 9.0 0.2 2.6 2 0 0 2 2 2 0 HalX domain WW PF00397.26 KIK54444.1 - 0.087 12.9 0.5 0.17 12.0 0.5 1.5 1 0 0 1 1 1 0 WW domain DUF4407 PF14362.6 KIK54444.1 - 5 6.4 8.4 8.9 5.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNF2_N PF00176.23 KIK54445.1 - 1.9e-55 188.0 0.2 8.1e-54 182.6 0.2 2.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK54445.1 - 3.5e-14 53.1 0.0 2.3e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KIK54445.1 - 1.9e-06 28.1 5.6 1.9e-06 28.1 5.6 2.5 2 0 0 2 2 2 1 Ring finger domain ResIII PF04851.15 KIK54445.1 - 3.3e-06 27.2 0.0 6.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIK54445.1 - 4.6e-06 26.4 7.3 4.6e-06 26.4 7.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KIK54445.1 - 1.7e-05 24.6 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 KIK54445.1 - 2e-05 24.3 4.7 2e-05 24.3 4.7 2.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK54445.1 - 2.1e-05 24.7 2.1 6.5e-05 23.1 2.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIK54445.1 - 0.00018 21.4 0.4 0.00018 21.4 0.4 2.8 2 2 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK54445.1 - 0.00026 20.8 4.4 0.00026 20.8 4.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KIK54445.1 - 0.00083 19.1 4.2 0.0026 17.5 4.2 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KIK54445.1 - 0.013 15.6 0.4 0.034 14.2 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KIK54445.1 - 0.12 12.3 1.1 0.27 11.2 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DEAD_2 PF06733.15 KIK54445.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 DEAD_2 zf-RING_5 PF14634.6 KIK54445.1 - 7.6 6.6 16.7 0.065 13.2 5.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DUF4133 PF13571.6 KIK54446.1 - 0.44 10.9 3.2 0.41 11.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) DUF202 PF02656.15 KIK54446.1 - 1.8 9.1 7.7 8.5 6.9 7.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) F-box-like PF12937.7 KIK54447.1 - 0.0075 16.1 0.6 0.02 14.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like Luteo_PO PF04662.13 KIK54448.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Luteovirus P0 protein Ank_2 PF12796.7 KIK54449.1 - 0.0052 17.4 0.2 0.01 16.4 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK54449.1 - 0.12 12.7 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK54450.1 - 2.5e-30 104.9 1.3 4.1e-06 27.3 0.0 8.2 8 1 1 9 9 9 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK54450.1 - 1.2e-23 80.6 0.4 0.063 13.9 0.0 11.5 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.6 KIK54450.1 - 1.1e-15 57.8 2.1 0.29 11.8 0.0 9.6 7 3 4 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 KIK54450.1 - 5.2e-15 55.1 0.4 0.36 11.4 0.0 9.0 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 KIK54450.1 - 5.8e-14 52.0 0.1 0.067 13.5 0.2 10.0 10 2 3 13 13 13 4 Ankyrin repeats (many copies) MnmE_helical PF12631.7 KIK54451.1 - 5.1e-43 147.6 0.2 6.6e-43 147.3 0.2 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KIK54451.1 - 2.4e-37 127.8 0.0 4.9e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KIK54451.1 - 1.1e-16 60.9 0.0 2.5e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK54451.1 - 7.1e-05 22.9 0.0 0.00017 21.7 0.0 1.5 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KIK54451.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK54451.1 - 0.032 14.1 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KIK54451.1 - 0.041 14.4 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KIK54451.1 - 0.064 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 KIK54452.1 - 3.5e-28 95.0 12.0 2.2e-07 29.9 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK54452.1 - 1e-23 83.5 5.1 2.3e-13 50.4 1.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK54452.1 - 4.5e-22 76.0 7.0 1.4e-05 24.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIK54452.1 - 1.1e-18 65.8 12.4 9.5e-06 24.9 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIK54452.1 - 5.1e-11 42.2 15.2 0.0086 15.9 1.8 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KIK54452.1 - 3.4e-07 30.2 5.7 0.00044 20.2 0.9 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIK54452.1 - 1.5e-05 25.3 0.0 0.027 14.8 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KIK54452.1 - 0.0013 19.1 0.2 0.29 11.5 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 KIK54452.1 - 0.084 13.1 2.4 1.2 9.4 2.3 2.6 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_1 PF00036.32 KIK54453.1 - 0.033 13.7 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 EF hand EF-hand_4 PF12763.7 KIK54453.1 - 0.15 12.0 0.1 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand ORC6 PF05460.13 KIK54454.1 - 6 6.0 11.9 21 4.2 11.8 1.8 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Tti2 PF10521.9 KIK54455.1 - 7.1e-46 157.0 0.0 1.1e-45 156.4 0.0 1.3 1 0 0 1 1 1 1 Tti2 family T2SSE_N PF05157.15 KIK54455.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain HEAT_EZ PF13513.6 KIK54455.1 - 0.094 13.3 1.6 0.39 11.3 0.2 2.8 3 0 0 3 3 3 0 HEAT-like repeat DASH_Dad3 PF08656.10 KIK54458.1 - 7.4e-23 80.4 0.3 9.1e-23 80.1 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 K-box PF01486.17 KIK54458.1 - 0.06 13.5 0.1 0.071 13.3 0.1 1.1 1 0 0 1 1 1 0 K-box region WD40 PF00400.32 KIK54459.1 - 1.3e-13 51.2 14.1 0.00097 19.9 0.1 7.1 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54459.1 - 1.5e-12 47.6 0.0 0.00011 22.4 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KIK54459.1 - 0.001 17.9 1.8 0.022 13.6 0.2 2.7 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 KIK54459.1 - 0.0057 16.6 0.7 0.29 11.0 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A NopRA1 PF16201.5 KIK54460.1 - 7.2e-53 179.2 1.5 2.9e-52 177.2 0.2 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 KIK54460.1 - 2.3e-48 165.3 0.0 2.1e-47 162.2 0.0 2.5 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal ETRAMP PF09716.10 KIK54466.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Aminotran_1_2 PF00155.21 KIK54467.1 - 5.8e-42 144.2 0.0 7.9e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M50B PF13398.6 KIK54468.1 - 4.9e-59 199.3 19.9 8.5e-59 198.6 19.9 1.3 1 0 0 1 1 1 1 Peptidase M50B-like DAGK_prokar PF01219.19 KIK54468.1 - 0.88 9.4 6.9 3.7 7.4 1.8 2.7 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase zf-C2H2_10 PF16588.5 KIK54469.1 - 0.0061 16.3 0.3 0.0083 15.8 0.3 1.2 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 KIK54469.1 - 0.088 12.6 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Zinc knuckle Bromodomain PF00439.25 KIK54470.1 - 1.7e-16 60.0 0.0 1.1e-10 41.4 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KIK54470.1 - 8.3e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain p450 PF00067.22 KIK54471.1 - 0.00061 18.7 0.0 0.024 13.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Nif11 PF07862.11 KIK54471.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Nif11 domain Ras PF00071.22 KIK54472.1 - 3e-62 209.0 0.2 3.5e-62 208.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK54472.1 - 9.6e-35 119.4 0.1 1.4e-34 118.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK54472.1 - 5.3e-12 45.5 0.0 6.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK54472.1 - 4e-07 30.1 0.1 6.3e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK54472.1 - 8.1e-05 22.6 0.1 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIK54472.1 - 0.00017 21.2 0.1 0.00057 19.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIK54472.1 - 0.0035 17.6 0.0 0.038 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KIK54472.1 - 0.0087 15.5 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK54472.1 - 0.016 14.6 0.1 0.021 14.2 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KIK54472.1 - 0.016 15.0 0.0 0.054 13.2 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KIK54472.1 - 0.02 15.3 0.1 0.03 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KIK54472.1 - 0.029 14.9 0.1 0.055 14.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KIK54472.1 - 0.032 13.8 0.1 0.097 12.2 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KIK54472.1 - 0.042 13.6 0.0 0.082 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIK54472.1 - 0.097 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 KIK54472.1 - 0.097 11.8 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 KIK54472.1 - 0.12 11.8 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region YvfG PF09628.10 KIK54472.1 - 0.15 12.4 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_21 PF13304.6 KIK54472.1 - 0.19 11.5 0.7 0.29 10.9 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system rhaM PF05336.13 KIK54473.1 - 6.3e-34 116.3 0.0 7e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Ribonuclease PF00545.20 KIK54474.1 - 1.7e-05 25.5 0.0 2.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Herpes_capsid PF06112.11 KIK54475.1 - 0.62 10.1 7.2 0.77 9.8 7.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Biotin_lipoyl PF00364.22 KIK54482.1 - 5.7e-15 54.9 0.2 8e-15 54.4 0.2 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme QRPTase_N PF02749.16 KIK54482.1 - 0.029 14.4 0.0 0.07 13.2 0.0 1.6 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 KIK54482.1 - 0.067 13.0 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 Biotin-lipoyl like DUF368 PF04018.13 KIK54483.1 - 0.16 11.5 9.8 0.31 10.6 7.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF368) Amidohydro_3 PF07969.11 KIK54484.1 - 6.7e-13 48.9 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK54484.1 - 2.3e-11 43.6 0.0 5.6e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KIK54484.1 - 2.4e-06 27.3 1.4 0.33 10.9 0.1 4.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Gpr1_Fun34_YaaH PF01184.19 KIK54486.1 - 9.9e-70 234.3 19.9 1.3e-69 233.9 19.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MIF PF01187.18 KIK54487.1 - 2.6e-15 56.7 0.0 2.8e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MBG_2 PF18676.1 KIK54487.1 - 0.066 13.9 0.0 0.082 13.6 0.0 1.2 1 0 0 1 1 1 0 MBG domain (YGX type) FAD_binding_3 PF01494.19 KIK54488.1 - 2.6e-23 82.8 0.1 2.6e-10 40.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 KIK54488.1 - 7.7e-05 23.2 0.1 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK54488.1 - 7.9e-05 22.8 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK54488.1 - 0.00054 19.3 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK54488.1 - 0.00075 19.2 0.0 0.0023 17.6 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK54488.1 - 0.013 14.7 0.0 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIK54488.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KIK54488.1 - 0.048 13.7 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KIK54488.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF1077 PF06417.12 KIK54489.1 - 1.9e-46 156.9 0.1 2.3e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RRM_1 PF00076.22 KIK54490.1 - 5.8e-35 118.9 0.0 4.5e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK54490.1 - 0.029 14.0 0.0 6.1 6.5 0.0 2.2 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KIK54490.1 - 0.1 12.3 0.2 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_7 PF16367.5 KIK54490.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Ras PF00071.22 KIK54492.1 - 5.8e-54 182.0 0.0 6.8e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK54492.1 - 4e-19 69.0 0.0 5.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK54492.1 - 3e-07 30.0 0.0 4.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 KIK54492.1 - 0.025 14.8 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial GTP_EFTU PF00009.27 KIK54492.1 - 0.032 13.8 0.1 0.21 11.1 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ANAPC4_WD40 PF12894.7 KIK54493.1 - 0.012 15.9 0.3 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK54493.1 - 0.084 13.8 1.8 0.57 11.1 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Lyx_isomer PF07385.12 KIK54494.1 - 0.022 14.0 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 D-lyxose isomerase TauD PF02668.16 KIK54496.1 - 4.1e-27 95.7 0.0 5.6e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KIK54496.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 CsiD Rpp20 PF12328.8 KIK54498.1 - 1.7e-06 28.0 0.0 0.00014 21.8 0.0 2.5 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KIK54498.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Alba eRF1_2 PF03464.15 KIK54499.1 - 8.2e-47 158.8 0.1 1.5e-46 158.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KIK54499.1 - 1.4e-39 135.1 0.5 2.9e-39 134.1 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KIK54499.1 - 1.6e-19 70.2 0.0 3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KIK54499.1 - 2e-10 41.0 0.1 3.2e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KIK54499.1 - 1.9e-08 34.6 0.0 3.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Transposase_21 PF02992.14 KIK54502.1 - 4.3e-07 29.4 0.0 1.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 TUG-UBL1 PF11470.8 KIK54504.1 - 0.024 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain AMP-binding PF00501.28 KIK54505.1 - 5e-77 259.3 0.0 3.6e-46 157.6 0.0 3.4 2 1 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KIK54505.1 - 2.9e-19 69.1 0.4 5.9e-13 48.3 0.3 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KIK54505.1 - 0.0047 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Peptidase_A22B PF04258.13 KIK54506.1 - 5.7e-71 239.3 5.5 7.7e-71 238.9 5.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Cript PF10235.9 KIK54507.1 - 0.035 14.7 0.3 0.052 14.1 0.3 1.4 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT GATA PF00320.27 KIK54508.1 - 2.2e-12 46.4 5.3 2.9e-12 46.0 5.3 1.2 1 0 0 1 1 1 1 GATA zinc finger C1_1 PF00130.22 KIK54508.1 - 0.024 14.5 2.7 0.029 14.2 2.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KIK54508.1 - 0.15 12.2 4.6 0.1 12.8 2.5 1.8 1 1 1 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KIK54508.1 - 1.9 8.3 10.9 0.66 9.8 0.5 2.5 2 1 0 2 2 2 0 A2L zinc ribbon domain Forkhead PF00250.18 KIK54509.1 - 5e-37 126.0 0.1 8.6e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 Forkhead domain SNF2_N PF00176.23 KIK54510.1 - 1.6e-54 185.0 1.3 4e-54 183.7 0.1 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK54510.1 - 6.4e-18 65.1 0.0 1.8e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK54510.1 - 1.6e-07 31.2 0.2 5.3e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK54510.1 - 9.2e-06 25.8 1.5 1.4e-05 25.2 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK54510.1 - 0.015 14.6 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase MSC PF09402.10 KIK54513.1 - 4.6e-70 236.7 0.0 6.3e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KIK54513.1 - 1.8e-09 37.1 0.0 4.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain CsgE PF10627.9 KIK54513.1 - 0.0055 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Curli assembly protein CsgE E1_UFD PF09358.10 KIK54513.1 - 0.022 15.4 0.0 0.07 13.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin fold domain DOT1 PF08123.13 KIK54514.1 - 6e-42 143.5 0.0 6.9e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KIK54514.1 - 0.025 15.3 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK54514.1 - 0.071 12.9 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK54514.1 - 0.074 13.7 0.0 0.13 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK54514.1 - 0.078 12.8 0.2 0.27 11.0 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIK54514.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KIK54514.1 - 0.2 11.1 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF1847 PF08901.11 KIK54515.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) WD40_like PF17005.5 KIK54515.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 KIK54518.1 - 3.6e-08 33.6 0.0 0.0082 16.4 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK54518.1 - 1.1e-05 26.1 4.9 0.0012 19.6 0.1 4.4 4 1 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK54518.1 - 0.001 18.7 2.1 0.87 9.1 0.2 2.7 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 KIK54518.1 - 0.0021 17.9 0.2 0.017 15.0 0.0 2.8 3 0 0 3 3 3 1 PQQ enzyme repeat Lactonase PF10282.9 KIK54518.1 - 0.0054 16.0 0.0 0.045 13.0 0.0 2.2 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 KIK54518.1 - 0.015 15.8 2.1 2.9 8.5 0.0 4.1 3 1 1 4 4 4 0 PQQ-like domain ELYS-bb PF16687.5 KIK54518.1 - 0.025 13.2 0.0 0.046 12.3 0.0 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin RecR PF02132.15 KIK54519.1 - 0.0015 18.0 0.8 0.0033 17.0 0.8 1.5 1 0 0 1 1 1 1 RecR protein DUF2542 PF10808.8 KIK54519.1 - 1.6 9.3 3.4 0.93 10.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2542) GATA PF00320.27 KIK54520.1 - 2.7e-16 58.8 13.0 6.4e-13 48.1 2.6 2.4 2 0 0 2 2 2 2 GATA zinc finger zf-RRN7 PF11781.8 KIK54520.1 - 0.02 14.5 0.0 0.02 14.5 0.0 3.4 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 KIK54520.1 - 0.065 12.8 0.4 0.065 12.8 0.4 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 KIK54520.1 - 0.08 13.1 0.6 0.08 13.1 0.6 2.5 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ZF-HD_dimer PF04770.12 KIK54520.1 - 0.19 12.1 7.1 1 9.7 0.4 2.6 2 1 0 2 2 2 0 ZF-HD protein dimerisation region Elf1 PF05129.13 KIK54520.1 - 0.37 10.9 4.0 2.1 8.5 1.1 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like C1_2 PF03107.16 KIK54520.1 - 1.5 9.2 9.1 7 7.1 3.0 2.9 2 1 0 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.10 KIK54520.1 - 3 8.0 7.1 0.75 10.0 0.4 2.6 3 0 0 3 3 3 0 Zinc ribbon domain WD40 PF00400.32 KIK54521.1 - 3e-05 24.7 1.1 0.95 10.4 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat NACHT PF05729.12 KIK54521.1 - 0.00032 20.6 0.1 0.0012 18.8 0.1 2.0 1 1 0 1 1 1 1 NACHT domain p450 PF00067.22 KIK54522.1 - 4.2e-13 48.8 0.0 4.6e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HMG_box PF00505.19 KIK54523.1 - 1.5e-07 31.7 2.3 2.5e-07 31.0 2.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK54523.1 - 2.4e-05 24.8 2.8 4.3e-05 24.0 2.8 1.4 1 0 0 1 1 1 1 HMG-box domain Porin_4 PF13609.6 KIK54526.1 - 0.0069 16.2 0.1 0.54 10.0 0.0 2.3 2 0 0 2 2 2 1 Gram-negative porin ShlB PF03865.13 KIK54526.1 - 0.017 14.6 2.8 0.77 9.2 0.2 2.4 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Gluconate_2-dh3 PF13618.6 KIK54526.1 - 0.03 14.5 1.6 0.24 11.6 0.2 2.5 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Fil_haemagg_2 PF13332.6 KIK54526.1 - 0.034 14.3 20.1 0.049 13.8 3.7 2.7 3 0 0 3 3 3 0 Hemagglutinin repeat Ysc84 PF04366.12 KIK54526.1 - 0.41 10.4 2.6 36 4.1 0.1 3.4 3 1 0 3 3 3 0 Las17-binding protein actin regulator F-box-like PF12937.7 KIK54528.1 - 0.01 15.7 4.3 0.018 15.0 0.1 3.2 4 0 0 4 4 4 1 F-box-like F-box_4 PF15966.5 KIK54528.1 - 0.063 13.2 1.5 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 F-box F-box PF00646.33 KIK54528.1 - 0.074 13.0 0.2 0.074 13.0 0.2 2.7 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK54529.1 - 0.003 17.4 0.1 0.0092 15.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK54529.1 - 0.022 14.7 0.6 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 F-box-like domain PsbK PF02533.15 KIK54530.1 - 0.036 14.2 0.3 0.11 12.7 0.3 1.8 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component Rad1 PF02144.16 KIK54531.1 - 5.2e-68 229.1 0.0 6.6e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Pyr_redox_2 PF07992.14 KIK54532.1 - 4.9e-65 219.6 0.4 8e-65 219.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIK54532.1 - 1.2e-31 109.2 0.2 2.8e-31 108.0 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIK54532.1 - 2.9e-21 75.8 4.0 9.5e-18 64.5 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK54532.1 - 6.6e-13 48.6 0.2 2.2e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK54532.1 - 8.7e-09 34.6 1.1 0.00013 20.8 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KIK54532.1 - 8.5e-07 28.7 0.0 1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIK54532.1 - 2e-05 23.9 0.1 5.2e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK54532.1 - 3e-05 24.2 0.6 7e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK54532.1 - 0.0016 17.6 2.1 0.0081 15.3 0.8 2.5 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KIK54532.1 - 0.0045 16.1 0.2 2.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KIK54532.1 - 0.013 14.6 1.1 0.03 13.4 0.2 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 KIK54532.1 - 0.048 12.9 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KIK54532.1 - 0.11 12.0 0.4 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF2779 PF11074.8 KIK54534.1 - 0.091 13.2 0.0 0.28 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) PI-PLC-X PF00388.19 KIK54535.1 - 0.00034 20.2 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pkinase_fungal PF17667.1 KIK54536.1 - 1.4e-11 43.8 0.1 3.3e-06 26.2 0.2 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK54536.1 - 0.051 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KIK54536.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK54536.1 - 0.17 11.2 0.1 0.32 10.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carn_acyltransf PF00755.20 KIK54537.1 - 5.8e-210 698.8 0.0 6.7e-210 698.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sterol-sensing PF12349.8 KIK54538.1 - 4.9e-35 120.6 8.2 1e-34 119.6 8.2 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIK54538.1 - 4.9e-12 44.8 6.5 7.1e-12 44.2 6.5 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KIK54538.1 - 0.63 11.0 2.2 82 4.3 0.2 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Biotin_lipoyl PF00364.22 KIK54539.1 - 2.2e-20 72.3 2.0 3.4e-20 71.6 1.4 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KIK54539.1 - 3.5e-09 36.9 0.0 1.2e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIK54539.1 - 0.0032 17.3 0.2 0.49 10.3 0.0 3.2 3 1 1 4 4 4 1 Biotin-lipoyl like CAP_N PF01213.19 KIK54539.1 - 2.7 7.4 10.7 5.7 6.3 10.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 KIK54540.1 - 1.4e-67 227.8 0.0 2.1e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54540.1 - 3.8e-38 131.2 0.0 4.7e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK54540.1 - 5.3e-15 55.5 0.0 8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK54540.1 - 7.2e-07 28.3 0.1 1.6e-06 27.2 0.1 1.7 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KIK54540.1 - 7e-05 22.3 0.5 0.0016 17.8 0.3 2.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK54540.1 - 0.0023 17.9 0.5 0.004 17.1 0.5 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK54540.1 - 0.097 11.6 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain GLTT PF01744.20 KIK54542.1 - 0.0028 17.4 0.6 1.6 8.6 0.2 2.8 1 1 1 2 2 2 2 GLTT repeat (6 copies) Amidohydro_3 PF07969.11 KIK54543.1 - 5.3e-13 49.3 0.0 8.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK54543.1 - 6.1e-12 45.5 0.0 3.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KIK54543.1 - 5.2e-09 35.8 0.7 3.5e-05 23.6 0.1 4.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ribonuclease_3 PF00636.26 KIK54544.1 - 1.2e-41 141.6 0.0 3.7e-20 72.5 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK54544.1 - 6.6e-26 91.0 0.0 1.2e-15 57.8 0.0 4.3 3 2 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 KIK54544.1 - 4.9e-15 55.8 0.1 1.5e-13 51.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK54544.1 - 3.7e-13 49.8 0.1 3.7e-13 49.8 0.1 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 KIK54544.1 - 5.8e-13 48.8 0.0 2.4e-12 46.9 0.0 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KIK54544.1 - 1.7e-12 47.5 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIK54544.1 - 0.00018 21.3 0.2 0.00043 20.0 0.0 1.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_26 PF13500.6 KIK54544.1 - 0.16 11.8 0.0 0.49 10.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Phosducin PF02114.16 KIK54545.1 - 1.4e-08 34.0 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Phosducin CMD PF02627.20 KIK54546.1 - 0.00054 19.9 0.1 0.0016 18.5 0.0 1.8 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family CMD PF02627.20 KIK54547.1 - 0.0025 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family 2OG-FeII_Oxy PF03171.20 KIK54549.1 - 7.9e-17 61.6 0.0 1.4e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK54549.1 - 2.2e-11 44.5 0.0 3.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal OxoDH_E1alpha_N PF12573.8 KIK54549.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal ABC_tran PF00005.27 KIK54550.1 - 9.3e-49 165.5 0.0 4.4e-23 82.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KIK54550.1 - 1.1e-44 152.4 41.2 2e-25 89.5 15.9 2.6 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.6 KIK54550.1 - 2.8e-11 43.8 0.2 0.0043 16.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIK54550.1 - 3.1e-08 34.2 0.1 0.0035 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK54550.1 - 3.8e-08 33.4 0.8 0.0098 15.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KIK54550.1 - 2.1e-07 30.6 1.1 0.0064 16.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KIK54550.1 - 6.9e-07 28.9 0.4 0.021 14.3 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK54550.1 - 1.6e-05 25.5 0.3 0.1 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIK54550.1 - 1.7e-05 24.5 0.0 0.089 12.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KIK54550.1 - 1.8e-05 25.0 0.3 0.099 12.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 KIK54550.1 - 0.00018 21.2 2.4 0.00018 21.2 2.4 2.9 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_28 PF13521.6 KIK54550.1 - 0.00025 21.3 1.3 0.052 13.8 0.3 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK54550.1 - 0.00032 20.7 0.3 0.98 9.3 0.1 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KIK54550.1 - 0.00061 20.1 0.1 2 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KIK54550.1 - 0.00071 20.1 0.2 0.36 11.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KIK54550.1 - 0.0017 18.1 0.7 1.7 8.3 0.0 2.8 4 0 0 4 4 2 2 AAA domain T2SSE PF00437.20 KIK54550.1 - 0.0039 16.3 0.2 0.22 10.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 KIK54550.1 - 0.0044 17.4 0.0 7.3 7.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIK54550.1 - 0.005 16.1 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 KIK54550.1 - 0.0067 16.0 0.6 1.6 8.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KIK54550.1 - 0.0074 16.4 1.8 4.1 7.5 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_5 PF07728.14 KIK54550.1 - 0.014 15.4 0.6 4 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK54550.1 - 0.017 14.9 0.4 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KIK54550.1 - 0.018 14.8 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain KAP_NTPase PF07693.14 KIK54550.1 - 0.019 14.2 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain MeaB PF03308.16 KIK54550.1 - 0.021 13.8 0.3 0.06 12.3 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KIK54550.1 - 0.023 14.8 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIK54550.1 - 0.025 14.3 0.1 18 4.9 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.6 KIK54550.1 - 0.027 14.9 0.1 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KIK54550.1 - 0.029 14.1 3.2 0.69 9.6 0.1 3.1 3 0 0 3 3 3 0 Cytidylate kinase Rad17 PF03215.15 KIK54550.1 - 0.038 13.9 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 KIK54550.1 - 0.05 13.0 0.7 9.4 5.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 KIK54550.1 - 0.057 13.3 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea dNK PF01712.19 KIK54550.1 - 0.066 13.1 0.2 8 6.2 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_19 PF13245.6 KIK54550.1 - 0.067 13.5 0.3 1.1 9.6 0.2 2.5 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIK54550.1 - 0.086 12.6 0.6 6.1 6.5 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 KIK54550.1 - 0.14 11.5 1.3 0.57 9.5 0.1 2.4 3 0 0 3 3 2 0 KaiC Pox_A32 PF04665.12 KIK54550.1 - 0.54 9.7 1.8 2 7.8 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 KIK54550.1 - 1.8 8.6 3.4 7 6.7 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 KIK54551.1 - 1.2e-48 165.1 0.0 5.8e-23 81.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KIK54551.1 - 2.1e-46 158.0 49.3 3.1e-26 92.1 21.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 KIK54551.1 - 2.2e-12 47.4 0.1 0.0044 16.9 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIK54551.1 - 1.6e-08 34.6 1.2 0.0042 17.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KIK54551.1 - 5.1e-08 32.6 1.8 0.01 15.3 0.3 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK54551.1 - 1e-07 32.5 0.2 0.0055 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIK54551.1 - 2.4e-07 30.4 1.6 0.0045 16.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK54551.1 - 4.1e-06 27.4 0.1 0.056 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIK54551.1 - 4.5e-06 26.4 0.0 0.14 11.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KIK54551.1 - 2.5e-05 24.6 0.4 0.11 12.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIK54551.1 - 0.00017 21.9 1.9 0.033 14.4 0.6 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK54551.1 - 0.00029 21.4 0.4 0.26 11.8 0.1 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KIK54551.1 - 0.00056 20.3 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KIK54551.1 - 0.00061 19.7 0.5 1.4 8.8 0.3 2.8 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 KIK54551.1 - 0.0012 18.2 0.0 0.041 13.1 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 KIK54551.1 - 0.0025 17.5 1.1 2.5 7.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain PDR_assoc PF08370.11 KIK54551.1 - 0.0042 16.8 4.1 0.017 14.9 2.5 2.7 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_33 PF13671.6 KIK54551.1 - 0.0052 17.0 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KIK54551.1 - 0.0053 16.4 0.7 1.8 8.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KIK54551.1 - 0.0057 15.8 0.2 0.35 9.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 KIK54551.1 - 0.007 16.8 0.0 2.9 8.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIK54551.1 - 0.0078 16.0 0.1 8 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 KIK54551.1 - 0.0093 15.9 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KIK54551.1 - 0.011 15.4 1.1 3.4 7.4 0.1 2.5 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 KIK54551.1 - 0.013 15.3 3.2 0.61 9.8 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase AAA_5 PF07728.14 KIK54551.1 - 0.013 15.5 1.5 3.8 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KIK54551.1 - 0.014 15.3 0.5 0.4 10.6 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KIK54551.1 - 0.014 15.1 0.2 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 KIK54551.1 - 0.018 15.1 2.9 4.2 7.5 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 KIK54551.1 - 0.018 14.9 0.1 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 KIK54551.1 - 0.022 15.2 0.3 0.9 10.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK54551.1 - 0.042 14.2 0.1 1.5 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KIK54551.1 - 0.043 13.1 0.0 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 KIK54551.1 - 0.062 12.6 0.5 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 KIK54551.1 - 0.088 12.1 0.3 0.81 9.0 0.1 2.3 2 0 0 2 2 2 0 KaiC MeaB PF03308.16 KIK54551.1 - 0.14 11.1 0.4 0.41 9.6 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 KIK54551.1 - 0.17 12.2 0.7 6.9 7.0 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KIK54551.1 - 0.25 11.0 0.6 4.6 6.9 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 KIK54551.1 - 0.38 10.5 1.5 13 5.5 0.4 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 KIK54551.1 - 1.8 7.9 3.8 2.2 7.7 0.5 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 KIK54551.1 - 2.9 7.9 4.1 11 6.0 1.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Lysine_decarbox PF03641.14 KIK54552.1 - 7.9e-34 116.6 0.0 1.1e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KIK54552.1 - 4.7e-10 39.3 0.1 7e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Sas10_Utp3 PF04000.15 KIK54553.1 - 8.4e-11 42.4 0.0 2.3e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Hat1_N PF10394.9 KIK54554.1 - 2.9e-55 186.9 0.7 2.9e-55 186.9 0.7 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KIK54554.1 - 0.00038 20.7 0.1 0.00091 19.4 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KIK54554.1 - 0.048 13.3 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 MOZ/SAS family Mac PF12464.8 KIK54554.1 - 0.061 13.6 0.9 0.13 12.5 0.9 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase V_ATPase_prox PF18274.1 KIK54554.1 - 0.073 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe GDA1_CD39 PF01150.17 KIK54556.1 - 3.9e-86 289.4 0.0 5.2e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Aldo_ket_red PF00248.21 KIK54557.1 - 5e-54 183.5 0.0 5.7e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_108 PF05838.12 KIK54557.1 - 0.17 12.4 0.4 43 4.7 0.1 3.0 2 1 0 2 2 2 0 Glycosyl hydrolase 108 PilJ PF13675.6 KIK54558.1 - 0.12 12.4 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Glyco_hydro_10 PF00331.20 KIK54560.1 - 2.1e-89 299.8 0.5 4.4e-89 298.8 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KIK54560.1 - 2.9e-15 55.9 11.6 6.7e-15 54.7 11.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain SOG2 PF10428.9 KIK54561.1 - 1.5 8.0 5.5 3.4 6.7 5.5 1.6 1 1 0 1 1 1 0 RAM signalling pathway protein NTF2 PF02136.20 KIK54562.1 - 4.5e-33 114.4 0.0 5.1e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain p450 PF00067.22 KIK54563.1 - 9e-38 130.2 0.0 1e-37 130.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54564.1 - 3e-07 29.6 0.0 3.6e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54565.1 - 4.4e-63 213.6 0.0 5.4e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_88 PF07470.13 KIK54566.1 - 1.7e-12 47.1 0.4 2.4e-12 46.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KIK54566.1 - 0.02 14.4 0.1 0.069 12.6 0.0 1.8 1 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus NPCBM PF08305.11 KIK54566.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 NPCBM/NEW2 domain LANC_like PF05147.13 KIK54566.1 - 0.077 11.6 0.0 0.17 10.5 0.0 1.5 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Plant_tran PF04827.14 KIK54566.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein Sporozoite_P67 PF05642.11 KIK54566.1 - 0.61 8.1 2.7 0.9 7.5 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dynamin_M PF01031.20 KIK54567.1 - 1.5e-100 336.1 0.0 2.8e-100 335.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK54567.1 - 1.1e-55 188.2 0.0 2.2e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK54567.1 - 6.2e-29 100.0 5.7 6.2e-29 100.0 5.7 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK54567.1 - 0.00015 21.9 0.1 0.0015 18.6 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KIK54567.1 - 0.9 9.2 4.7 0.85 9.3 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain Glyco_hydro_16 PF00722.21 KIK54568.1 - 6.7e-08 32.2 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAP1 PF08601.10 KIK54568.1 - 1.6 8.4 11.0 2.2 7.9 11.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 KIK54568.1 - 6.1 5.3 6.6 7.4 5.0 6.6 1.1 1 0 0 1 1 1 0 Macoilin family TBP PF00352.21 KIK54569.1 - 6.7e-44 147.8 0.2 6.8e-27 93.2 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KIK54569.1 - 0.00027 21.0 0.0 0.86 9.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Swi5 PF07061.11 KIK54571.1 - 3.7e-18 65.4 0.3 3.8e-18 65.3 0.3 1.0 1 0 0 1 1 1 1 Swi5 RCC1 PF00415.18 KIK54572.1 - 4.6e-32 110.4 12.1 3.6e-07 30.7 0.4 7.0 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK54572.1 - 7.4e-09 35.2 32.7 9.7e-05 22.1 1.9 7.7 8 1 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat tRNA-synt_1b PF00579.25 KIK54573.1 - 1.8e-20 73.4 0.0 1.1e-19 70.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SRP54 PF00448.22 KIK54574.1 - 0.0072 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KIK54574.1 - 0.0086 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 KIK54574.1 - 0.054 13.5 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KIK54574.1 - 0.057 13.3 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK54574.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.19 KIK54576.1 - 2.9e-07 30.3 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease KDZ PF18758.1 KIK54578.1 - 9.1e-11 41.8 0.6 1.1e-10 41.5 0.6 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RNA_pol_I_A49 PF06870.12 KIK54578.1 - 0.13 11.1 0.2 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor SRP72 PF08492.12 KIK54580.1 - 0.1 13.1 2.9 0.28 11.6 2.9 1.8 1 1 0 1 1 1 0 SRP72 RNA-binding domain PGA2 PF07543.12 KIK54580.1 - 2.8 7.9 11.3 1.6 8.7 6.0 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Nucleo_P87 PF07267.11 KIK54580.1 - 9.1 5.0 7.0 2.3 7.0 0.6 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Latarcin PF10279.9 KIK54582.1 - 0.023 15.1 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Latarcin precursor Mitochondr_Som1 PF11093.8 KIK54582.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Nop14 PF04147.12 KIK54583.1 - 0.014 13.7 34.8 0.02 13.1 34.8 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KIK54583.1 - 0.044 11.9 34.0 0.082 11.0 34.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi V_ATPase_I PF01496.19 KIK54583.1 - 3.8 5.3 4.2 5.5 4.8 4.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2151 PF10221.9 KIK54583.1 - 9.7 4.6 9.1 13 4.3 9.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Retrotran_gag_2 PF14223.6 KIK54584.1 - 2.1e-11 43.7 0.0 3.9e-11 42.8 0.0 1.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK54584.1 - 1.5e-08 34.1 0.0 3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) CBFD_NFYB_HMF PF00808.23 KIK54586.1 - 3.1e-20 72.2 1.4 4.6e-20 71.7 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK54586.1 - 5.6e-14 52.6 0.1 1e-13 51.8 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KIK54586.1 - 0.033 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Suf PF05843.14 KIK54587.1 - 9.5 6.1 7.6 11 5.9 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RRM_1 PF00076.22 KIK54588.1 - 4.5e-31 106.5 0.2 5.9e-16 58.0 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK54588.1 - 1.8e-09 37.6 0.0 0.0012 18.9 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK54588.1 - 6.9e-05 22.8 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KIK54588.1 - 0.0014 18.3 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_3 PF08777.11 KIK54588.1 - 0.0023 17.9 0.0 0.089 12.8 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif GATase_5 PF13507.6 KIK54589.1 - 1.1e-99 332.8 0.0 1.6e-99 332.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KIK54589.1 - 3.6e-41 140.9 0.4 5.9e-28 98.0 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KIK54589.1 - 1.3e-32 112.2 0.1 2.5e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KIK54589.1 - 6.1e-22 77.9 0.0 2.6e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain TruB_C PF09142.11 KIK54589.1 - 0.075 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PRD PF00874.20 KIK54589.1 - 0.14 12.5 0.0 0.69 10.2 0.0 2.0 2 0 0 2 2 2 0 PRD domain Tektin PF03148.14 KIK54589.1 - 0.31 9.7 0.7 0.84 8.3 0.1 1.8 2 0 0 2 2 2 0 Tektin family SRAP PF02586.14 KIK54590.1 - 8.5e-65 218.4 1.5 6.9e-34 117.3 0.3 2.1 1 1 1 2 2 2 2 SOS response associated peptidase (SRAP) eIF-5a PF01287.20 KIK54591.1 - 6.8e-29 99.8 0.5 9.3e-29 99.3 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KIK54591.1 - 0.026 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain LIM PF00412.22 KIK54592.1 - 5.6e-24 84.1 19.5 3.3e-12 46.4 7.3 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KIK54592.1 - 0.00056 19.4 18.6 1.6 8.4 0.3 5.2 5 0 0 5 5 5 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KIK54592.1 - 0.01 15.9 19.4 0.98 9.6 0.8 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-ACC PF17848.1 KIK54592.1 - 0.019 15.1 6.1 5.9 7.1 0.3 3.6 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Glucokinase PF02685.16 KIK54592.1 - 0.063 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucokinase DUF4428 PF14471.6 KIK54592.1 - 0.089 12.7 4.8 3.9 7.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) E6 PF00518.17 KIK54592.1 - 0.82 10.1 7.5 0.69 10.4 1.4 2.5 2 0 0 2 2 2 0 Early Protein (E6) zinc_ribbon_13 PF09855.9 KIK54592.1 - 4.6 7.5 7.1 1 9.6 1.2 2.9 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) YacG PF03884.14 KIK54592.1 - 4.8 7.0 15.6 5.5 6.8 0.2 4.2 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG Lar_restr_allev PF14354.6 KIK54592.1 - 5.8 7.4 17.4 1.5 9.3 4.1 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar PIH1 PF08190.12 KIK54593.1 - 4.7e-21 75.0 0.4 9.1e-21 74.0 0.4 1.4 1 1 0 1 1 1 1 PIH1 N-terminal domain DAHP_synth_1 PF00793.20 KIK54594.1 - 6.6e-98 326.9 0.0 8.2e-98 326.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SAP PF02037.27 KIK54595.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain MCM2_N PF12619.8 KIK54595.1 - 0.019 15.3 0.4 0.019 15.3 0.4 1.6 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 zf-RanBP PF00641.18 KIK54597.1 - 0.00098 18.4 20.5 0.005 16.1 3.0 2.9 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others Sec23_helical PF04815.15 KIK54597.1 - 0.1 12.4 1.0 0.26 11.1 1.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain TFIIA PF03153.13 KIK54597.1 - 6.2 6.7 13.2 0.5 10.3 8.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peroxin-13_N PF04088.13 KIK54598.1 - 2.5e-45 154.3 0.0 3.2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KIK54598.1 - 1.9e-10 40.2 2.3 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIK54598.1 - 2.2e-09 36.9 0.1 4.1e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK54598.1 - 4e-05 23.4 1.2 0.00016 21.4 1.2 1.9 1 1 0 1 1 1 1 Variant SH3 domain DUF4515 PF14988.6 KIK54599.1 - 0.082 12.7 2.1 0.14 12.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Abhydrolase_1 PF00561.20 KIK54600.1 - 1.2e-10 41.5 0.0 5.4e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK54600.1 - 9e-07 29.7 0.0 1.3e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KIK54600.1 - 2.9e-05 22.9 0.0 3.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KIK54600.1 - 0.0069 15.7 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Hydrolase_4 PF12146.8 KIK54601.1 - 2.2e-11 43.5 0.1 5.7e-11 42.1 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK54601.1 - 2.2e-11 44.8 0.4 1.1e-10 42.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIK54601.1 - 4.8e-08 33.1 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KIK54601.1 - 7.3e-07 29.1 0.1 4.2e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.12 KIK54601.1 - 0.0023 16.9 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KIK54601.1 - 0.0029 17.1 0.0 0.0066 15.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KIK54601.1 - 0.0067 16.6 0.0 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain DUF1057 PF06342.12 KIK54601.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 KIK54601.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3089 PF11288.8 KIK54601.1 - 0.042 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.16 KIK54601.1 - 0.049 13.4 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 KIK54601.1 - 0.087 12.7 0.0 0.46 10.3 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase UPF0052 PF01933.18 KIK54602.1 - 2.9e-46 158.0 0.0 3.6e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Phage_holin_3_6 PF07332.11 KIK54604.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3341 PF11821.8 KIK54604.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Syndecan PF01034.20 KIK54604.1 - 0.27 11.2 0.3 0.6 10.1 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain EVC2_like PF12297.8 KIK54604.1 - 0.3 9.7 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Ribosomal_S6e PF01092.19 KIK54605.1 - 5.5e-57 191.2 0.0 9.9e-57 190.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e MKLP1_Arf_bdg PF16540.5 KIK54605.1 - 0.12 12.4 2.6 0.27 11.3 1.5 2.0 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Cnn_1N PF07989.11 KIK54606.1 - 8e-24 83.6 9.7 8e-24 83.6 9.7 12.2 6 4 4 12 12 11 1 Centrosomin N-terminal motif 1 Filament PF00038.21 KIK54606.1 - 3.7e-05 23.5 132.2 0.032 13.8 12.0 8.1 2 2 6 8 8 8 4 Intermediate filament protein Fez1 PF06818.15 KIK54606.1 - 0.00018 22.0 27.2 0.00018 22.0 27.2 7.7 1 1 6 7 7 6 2 Fez1 Mto2_bdg PF12808.7 KIK54606.1 - 0.00048 20.4 8.5 0.00048 20.4 8.5 11.9 10 3 2 12 12 10 2 Micro-tubular organiser Mto1 C-term Mto2-binding region BRE1 PF08647.11 KIK54606.1 - 0.0014 18.7 6.6 0.0014 18.7 6.6 12.2 2 2 12 15 15 14 3 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 KIK54606.1 - 0.015 15.3 1.9 0.015 15.3 1.9 9.1 2 2 7 9 9 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 KIK54606.1 - 0.017 15.7 10.0 0.017 15.7 10.0 12.5 2 2 12 14 14 14 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KIK54606.1 - 0.099 11.5 146.0 0.018 13.9 20.7 8.5 2 2 7 9 9 9 0 Spc7 kinetochore protein OFCC1 PF15680.5 KIK54606.1 - 0.28 11.7 9.7 0.073 13.6 0.7 4.3 3 1 1 4 4 4 0 Orofacial cleft 1 candidate gene 1 protein AAA-ATPase_like PF09820.9 KIK54606.1 - 1.4 8.3 8.8 0.27 10.6 3.1 2.8 2 1 0 2 2 2 0 Predicted AAA-ATPase Baculo_PEP_C PF04513.12 KIK54606.1 - 3.9 7.5 66.9 1.2 9.2 0.9 9.0 3 2 6 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 KIK54607.1 - 5.7e-42 143.5 0.0 5.1e-24 85.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK54607.1 - 2.6e-38 132.3 27.4 3e-25 89.4 12.1 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK54607.1 - 7.9e-07 28.7 2.6 0.006 16.0 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK54607.1 - 5.8e-05 23.1 5.6 0.54 10.0 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KIK54607.1 - 6e-05 22.2 0.0 0.1 11.6 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.6 KIK54607.1 - 8.5e-05 22.2 0.1 0.24 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK54607.1 - 0.00011 22.7 0.1 0.16 12.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIK54607.1 - 0.00064 20.3 0.1 0.063 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK54607.1 - 0.00092 18.8 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK54607.1 - 0.0023 18.1 0.2 0.073 13.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 KIK54607.1 - 0.0072 15.9 0.0 4.8 6.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KIK54607.1 - 0.0088 16.3 0.0 3.5 7.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KIK54607.1 - 0.0092 15.5 0.5 2.1 7.7 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 KIK54607.1 - 0.027 13.4 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KIK54607.1 - 0.029 14.4 0.2 0.87 9.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KIK54607.1 - 0.047 13.0 0.0 9.8 5.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KIK54607.1 - 0.054 13.2 0.1 17 5.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.15 KIK54607.1 - 0.061 13.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KIK54607.1 - 0.076 12.9 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SPC22 PF04573.12 KIK54608.1 - 9.8e-26 90.2 0.0 1e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit VHS PF00790.19 KIK54609.1 - 3.8e-11 43.0 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIK54609.1 - 2.9e-06 27.5 0.9 0.052 13.9 0.4 2.6 2 0 0 2 2 2 2 GAT domain Zip PF02535.22 KIK54609.1 - 0.29 10.3 2.7 0.54 9.4 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PAPA-1 PF04795.12 KIK54610.1 - 1.7e-14 54.4 9.5 1.7e-14 54.4 9.5 5.8 3 3 0 3 3 3 1 PAPA-1-like conserved region NmrA PF05368.13 KIK54611.1 - 3.4e-28 98.8 0.0 4.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK54611.1 - 1e-11 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK54611.1 - 0.00056 19.5 0.0 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIK54611.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Redoxin PF08534.10 KIK54613.1 - 5e-29 100.9 0.0 6.2e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIK54613.1 - 4.7e-11 42.7 0.0 5.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PS_Dcarbxylase PF02666.15 KIK54614.1 - 3.5e-46 157.3 0.0 7e-46 156.3 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase TPR_10 PF13374.6 KIK54615.1 - 4.3e-78 255.3 0.4 8.1e-09 35.1 0.0 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54615.1 - 3.6e-56 187.4 15.2 1.2e-10 41.5 0.4 9.0 2 1 8 10 10 10 9 Tetratricopeptide repeat Ribosomal_S13_N PF08069.12 KIK54615.1 - 6.5e-22 77.3 0.0 3.1e-21 75.1 0.0 2.2 2 0 0 2 2 1 1 Ribosomal S13/S15 N-terminal domain TPR_7 PF13176.6 KIK54615.1 - 1.5e-11 43.5 4.1 8.7 6.6 0.0 8.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54615.1 - 2.8e-11 42.7 14.4 3.2 7.7 0.1 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK54615.1 - 7.9e-11 42.3 1.0 0.016 15.7 0.0 6.9 3 2 5 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK54615.1 - 8.6e-11 41.2 11.3 0.076 13.3 0.0 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK54615.1 - 3.8e-10 39.1 15.6 6.9 7.0 0.0 10.0 11 0 0 11 11 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK54615.1 - 2e-08 34.3 5.8 0.26 11.5 0.0 7.2 6 1 2 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KIK54615.1 - 5.5e-07 29.3 13.7 0.0057 16.1 1.6 4.3 2 1 1 4 4 4 3 MalT-like TPR region TPR_20 PF14561.6 KIK54615.1 - 2.7e-06 27.6 2.6 43 4.5 0.0 7.6 2 2 6 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK54615.1 - 2.7e-05 24.4 0.0 31 5.6 0.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat NB-ARC PF00931.22 KIK54615.1 - 7.6e-05 22.0 0.1 0.0004 19.6 0.1 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_9 PF13371.6 KIK54615.1 - 8.5e-05 22.6 0.1 1.4 9.2 0.0 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat YqaH PF17448.2 KIK54615.1 - 9.1e-05 22.7 0.3 5.4 7.4 0.0 5.0 2 1 2 5 5 5 1 Uncharacterized YqaH-like TPR_3 PF07720.12 KIK54615.1 - 9.3e-05 22.3 3.9 4.9 7.2 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat PPR PF01535.20 KIK54615.1 - 9.4e-05 22.4 3.0 23 5.5 0.0 7.3 8 0 0 8 8 8 0 PPR repeat Paf67 PF10255.9 KIK54615.1 - 0.00013 21.1 0.0 4.2 6.3 0.0 3.5 1 1 2 3 3 3 2 RNA polymerase I-associated factor PAF67 TPR_6 PF13174.6 KIK54615.1 - 0.00072 20.0 2.2 54 4.7 0.0 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK54615.1 - 0.0011 19.6 0.2 11 6.7 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIK54615.1 - 0.0029 17.6 3.8 5.1 7.2 0.1 6.0 1 1 4 5 5 5 1 Putative TPR-like repeat SPOB_a PF14689.6 KIK54615.1 - 0.0033 17.1 7.0 19 5.0 0.0 6.0 6 1 0 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain AAA_16 PF13191.6 KIK54615.1 - 0.0036 17.7 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Foie-gras_1 PF11817.8 KIK54615.1 - 0.021 14.4 11.1 0.053 13.1 0.5 4.6 5 1 0 7 7 6 0 Foie gras liver health family 1 AAA_22 PF13401.6 KIK54615.1 - 0.028 14.7 0.1 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK54615.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MCPVI PF02993.14 KIK54615.1 - 0.075 12.9 3.5 17 5.1 0.1 4.1 1 1 2 4 4 4 0 Minor capsid protein VI DUF2977 PF11192.8 KIK54615.1 - 0.13 12.4 0.0 33 4.7 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2977) Carbam_trans_N PF02543.15 KIK54616.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Glyco_hydro_3 PF00933.21 KIK54622.1 - 2.3e-50 171.8 0.0 7.9e-43 147.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain tRNA-synt_1 PF00133.22 KIK54623.1 - 3.3e-14 52.1 0.0 1.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KIK54623.1 - 6.5e-07 28.4 0.0 6.5e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (M) Phage_T7_Capsid PF05396.11 KIK54624.1 - 0.18 12.1 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage T7 capsid assembly protein HCV_capsid PF01543.17 KIK54626.1 - 0.022 14.9 0.3 0.025 14.8 0.3 1.1 1 0 0 1 1 1 0 Hepatitis C virus capsid protein tRNA-synt_1 PF00133.22 KIK54628.1 - 1.9e-39 135.4 0.0 1.4e-29 102.9 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KIK54628.1 - 3e-15 55.9 0.0 2.3e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KIK54628.1 - 3.5e-15 56.3 0.1 1.5e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KIK54628.1 - 2.6e-09 36.9 0.0 6.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KIK54628.1 - 0.0068 15.4 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.6 KIK54628.1 - 0.15 11.5 0.5 0.51 9.8 0.0 2.1 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 AAA_16 PF13191.6 KIK54633.1 - 0.029 14.7 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 KIK54633.1 - 0.035 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 KIK54633.1 - 0.08 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK54633.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 KIK54634.1 - 1.2e-147 492.5 0.1 1.4e-147 492.3 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 KIK54634.1 - 0.031 14.6 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor EAL PF00563.20 KIK54634.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 EAL domain DHO_dh PF01180.21 KIK54635.1 - 4.4e-18 65.5 0.0 9.7e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Rota_NSP4 PF01452.16 KIK54637.1 - 0.15 11.7 1.1 0.21 11.3 0.6 1.5 1 1 0 1 1 1 0 Rotavirus non structural protein DUF3357 PF11837.8 KIK54639.1 - 0.022 15.2 0.7 0.041 14.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) PQ-loop PF04193.14 KIK54640.1 - 2.9e-25 87.8 5.3 7.6e-12 44.8 1.4 2.7 2 0 0 2 2 2 2 PQ loop repeat RNase_PH PF01138.21 KIK54642.1 - 4.9e-10 40.0 0.0 1.2e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Bromo_TP PF07524.13 KIK54643.1 - 1.4e-07 31.4 0.1 2.4e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KIK54643.1 - 0.0014 19.0 0.3 0.004 17.5 0.3 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cullin PF00888.22 KIK54644.1 - 5e-06 25.4 0.0 6.6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family DUF3856 PF12968.7 KIK54644.1 - 0.03 14.4 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) Erythro_esteras PF05139.14 KIK54644.1 - 0.044 13.6 0.0 0.2 11.4 0.0 1.9 2 1 0 2 2 2 0 Erythromycin esterase YqzH PF14164.6 KIK54644.1 - 3.1 7.9 5.0 0.98 9.5 0.3 2.6 3 1 0 3 3 3 0 YqzH-like protein Collagen PF01391.18 KIK54645.1 - 2 8.2 11.8 2.3 8.0 1.6 3.1 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF3433 PF11915.8 KIK54647.1 - 9.9e-17 61.2 1.3 2.4e-16 59.9 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Use1 PF09753.9 KIK54648.1 - 1.6e-18 67.4 5.0 3e-17 63.2 5.0 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 Ring_hydroxyl_A PF00848.19 KIK54648.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) DUF87 PF01935.17 KIK54648.1 - 0.49 10.4 3.0 0.6 10.2 0.2 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Cortex-I_coil PF09304.10 KIK54648.1 - 1.2 9.4 5.8 1.6 9.0 0.8 2.3 2 1 0 2 2 2 0 Cortexillin I, coiled coil Fungal_trans PF04082.18 KIK54649.1 - 1.4e-18 66.9 0.0 2.1e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK54649.1 - 2.7e-06 27.4 8.8 4.9e-06 26.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S15 PF02129.18 KIK54650.1 - 1.7e-09 37.7 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIK54650.1 - 2e-08 33.8 0.1 1.5e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK54650.1 - 2.3e-07 30.8 0.0 0.0044 16.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK54650.1 - 3.6e-05 24.5 4.7 0.0005 20.7 0.4 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 KIK54650.1 - 0.00099 18.0 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK54650.1 - 0.001 18.6 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KIK54650.1 - 0.061 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Pribosyltran PF00156.27 KIK54650.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Aminotran_1_2 PF00155.21 KIK54651.1 - 1.1e-32 113.6 0.0 2.6e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II TEP1_N PF05386.11 KIK54651.1 - 0.021 14.4 0.1 0.49 10.0 0.0 2.6 2 0 0 2 2 2 0 TEP1 N-terminal domain Sugar_tr PF00083.24 KIK54653.1 - 8.7e-84 282.0 24.2 1.1e-83 281.7 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK54653.1 - 1.5e-23 83.3 21.2 1.5e-23 83.3 21.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK54653.1 - 0.00029 19.4 0.8 0.00029 19.4 0.8 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CUE PF02845.16 KIK54654.1 - 2.5e-05 23.9 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain HEAT_PBS PF03130.16 KIK54655.1 - 0.084 13.6 1.2 5.6 7.9 0.0 2.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Prominin PF05478.11 KIK54656.1 - 0.017 13.1 0.2 0.023 12.7 0.2 1.1 1 0 0 1 1 1 0 Prominin Arg_tRNA_synt_N PF03485.16 KIK54657.1 - 0.03 14.9 0.1 2.9 8.6 0.0 2.7 2 1 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain MscS_porin PF12795.7 KIK54657.1 - 1.2 8.6 6.9 0.28 10.7 3.4 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain MFS_1 PF07690.16 KIK54658.1 - 2.4e-43 148.4 36.5 2.1e-42 145.3 15.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK54658.1 - 3.1e-09 36.2 12.6 3.1e-09 36.2 12.6 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK54658.1 - 5.5e-06 25.9 8.3 5.5e-06 25.9 8.3 1.8 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KIK54658.1 - 0.00023 19.7 6.9 0.00035 19.1 6.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIK54658.1 - 0.0011 18.0 12.2 0.0011 18.0 12.2 3.1 2 1 2 4 4 4 1 MFS_1 like family ATPase_gene1 PF09527.10 KIK54658.1 - 0.0079 16.3 0.7 0.0079 16.3 0.7 4.0 6 0 0 6 6 6 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter COesterase PF00135.28 KIK54659.1 - 3.4e-108 362.7 0.0 4.6e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK54659.1 - 1.4e-08 34.9 0.0 5.8e-08 32.8 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK54659.1 - 0.0039 16.7 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DSPc PF00782.20 KIK54660.1 - 1.2e-17 63.9 0.0 3.4e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CTP_transf_like PF01467.26 KIK54661.1 - 2.3e-24 86.2 0.0 3.3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF3363 PF11843.8 KIK54661.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) CagX PF03524.15 KIK54661.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Aldo_ket_red PF00248.21 KIK54662.1 - 2.1e-44 151.9 0.3 3.6e-42 144.6 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3403 PF11883.8 KIK54664.1 - 0.015 15.4 5.5 0.42 10.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3403) PATR PF12951.7 KIK54664.1 - 0.2 11.8 0.9 13 6.0 0.1 2.5 2 0 0 2 2 2 0 Passenger-associated-transport-repeat Ntox24 PF15529.6 KIK54664.1 - 0.21 11.9 6.2 5 7.5 0.7 2.3 2 0 0 2 2 2 0 Bacterial toxin 24 DUF3519 PF12033.8 KIK54664.1 - 0.25 11.7 11.0 1.3 9.4 0.5 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3519) TFA2_Winged_2 PF18121.1 KIK54665.1 - 5.1e-21 74.1 0.1 1.2e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KIK54665.1 - 1.8e-15 57.0 2.2 2.9e-15 56.3 0.7 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain OB_NTP_bind PF07717.16 KIK54666.1 - 2.5e-19 69.4 0.3 6.7e-19 68.0 0.3 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KIK54666.1 - 3.9e-18 65.7 0.0 3.9e-18 65.7 0.0 4.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK54666.1 - 6.3e-15 55.5 0.1 4.1e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK54666.1 - 4.1e-08 33.2 0.2 4.4e-07 29.8 0.0 2.8 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KIK54666.1 - 0.00022 21.0 0.0 0.00058 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK54666.1 - 0.00054 20.2 0.0 0.0028 17.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK54666.1 - 0.0008 19.8 0.6 0.0025 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIK54666.1 - 0.019 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KIK54666.1 - 3.8 7.5 9.1 0.95 9.4 0.1 3.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Pox_E2-like PF04497.12 KIK54667.1 - 0.21 10.0 0.0 0.24 9.8 0.0 1.0 1 0 0 1 1 1 0 Poxviridae protein MFS_1 PF07690.16 KIK54668.1 - 1.7e-23 83.1 70.9 2.9e-13 49.5 33.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.11 KIK54668.1 - 0.47 10.1 5.1 0.29 10.8 0.9 3.0 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 DUF4077 PF13295.6 KIK54668.1 - 2.4 8.1 6.4 4.1 7.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4077) Pan3_PK PF18101.1 KIK54669.1 - 2.2e-63 212.3 0.1 3.4e-63 211.7 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KIK54669.1 - 5e-05 22.8 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54669.1 - 0.0027 17.0 0.0 0.0065 15.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DCAF17 PF15802.5 KIK54669.1 - 0.02 13.6 0.2 0.071 11.8 0.2 1.9 1 1 0 1 1 1 0 DDB1- and CUL4-associated factor 17 zf-CCCH PF00642.24 KIK54669.1 - 0.1 12.6 2.4 0.27 11.2 2.4 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M49 PF03571.15 KIK54670.1 - 7.3e-222 737.6 0.0 8.6e-222 737.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Erp_C PF06780.11 KIK54670.1 - 0.076 13.0 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Erp protein C-terminus F-box PF00646.33 KIK54671.1 - 1.4e-06 28.0 0.6 3.5e-06 26.7 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK54671.1 - 7.5e-06 25.7 0.7 1.6e-05 24.7 0.7 1.6 1 0 0 1 1 1 1 F-box-like Cys_Met_Meta_PP PF01053.20 KIK54673.1 - 9e-146 485.3 0.0 1e-145 485.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIK54673.1 - 2.6e-12 46.7 0.2 7.8e-12 45.2 0.3 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIK54673.1 - 3.1e-10 39.8 0.1 4.9e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIK54673.1 - 2.3e-09 36.7 0.3 6.6e-09 35.2 0.1 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK54673.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KIK54673.1 - 0.0046 15.5 0.1 0.0068 15.0 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KIK54673.1 - 0.0085 15.0 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SepSecS PF05889.13 KIK54673.1 - 0.045 12.4 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF99 PF01949.16 KIK54673.1 - 0.19 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 FAD_binding_3 PF01494.19 KIK54674.1 - 7.3e-12 45.2 0.0 5.9e-11 42.2 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain CHAT PF12770.7 KIK54675.1 - 3.2e-21 76.0 0.0 5.9e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_19 PF14559.6 KIK54675.1 - 0.02 15.4 0.1 1.5 9.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf_UBZ PF18439.1 KIK54675.1 - 0.27 10.9 1.3 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF4274 PF14096.6 KIK54676.1 - 0.015 15.2 1.3 0.1 12.6 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4274) Phage_int_SAM_4 PF13495.6 KIK54676.1 - 0.096 13.2 0.2 0.13 12.8 0.2 1.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Seryl_tRNA_N PF02403.22 KIK54677.1 - 0.014 15.6 9.4 1.4 9.2 0.1 4.5 4 1 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain SPT16 PF08644.11 KIK54677.1 - 0.015 15.5 0.1 0.049 13.8 0.1 1.9 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Spectrin PF00435.21 KIK54677.1 - 0.037 14.5 10.3 5.3 7.6 0.1 5.1 4 1 1 5 5 5 0 Spectrin repeat Maelstrom PF13017.6 KIK54677.1 - 0.039 13.6 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 piRNA pathway germ-plasm component HMMR_C PF15908.5 KIK54677.1 - 0.38 11.0 6.2 6.8 6.9 0.1 3.9 4 0 0 4 4 4 0 Hyaluronan mediated motility receptor C-terminal FlaC_arch PF05377.11 KIK54677.1 - 0.4 11.1 5.7 11 6.5 0.2 4.5 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 KIK54677.1 - 0.43 10.8 14.0 3.6 7.8 1.2 4.4 4 1 0 4 4 4 0 Flagellar FliJ protein BLOC1_2 PF10046.9 KIK54677.1 - 0.61 10.4 12.5 3.5 8.0 0.5 4.9 5 1 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Carbpep_Y_N PF05388.11 KIK54677.1 - 0.63 10.6 11.5 0.75 10.3 0.6 4.6 4 1 1 5 5 5 0 Carboxypeptidase Y pro-peptide Prefoldin PF02996.17 KIK54677.1 - 0.65 9.9 12.2 4 7.4 0.4 4.2 4 0 0 4 4 4 0 Prefoldin subunit Bacillus_HBL PF05791.11 KIK54677.1 - 0.68 9.7 15.6 0.41 10.4 0.8 4.2 4 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF745 PF05335.13 KIK54677.1 - 0.96 9.1 12.9 0.86 9.3 0.3 3.8 4 1 0 4 4 3 0 Protein of unknown function (DUF745) TMF_TATA_bd PF12325.8 KIK54677.1 - 0.97 9.7 4.1 41 4.4 0.0 4.1 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 KIK54677.1 - 1 9.9 17.0 12 6.5 0.3 5.1 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KIK54677.1 - 1.3 9.3 13.8 7.3 6.9 0.9 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 KIK54677.1 - 1.9 9.1 9.7 20 5.8 0.1 5.0 5 1 1 6 6 6 0 Syntaxin 6, N-terminal SKA2 PF16740.5 KIK54677.1 - 2.2 8.1 5.9 0.66 9.8 0.2 3.0 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 TACC_C PF05010.14 KIK54677.1 - 2.8 7.7 7.1 1.4 8.7 0.1 3.0 4 0 0 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Nsp1_C PF05064.13 KIK54677.1 - 4.3 7.2 7.7 28 4.6 1.0 3.9 3 1 1 4 4 4 0 Nsp1-like C-terminal region YabA PF06156.13 KIK54677.1 - 4.5 8.0 6.2 15 6.3 0.1 4.0 4 0 0 4 4 4 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 KIK54677.1 - 7.3 6.8 5.9 26 5.0 0.1 3.6 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 KIK54678.1 - 0.0009 19.5 0.6 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain SPT16 PF08644.11 KIK54678.1 - 0.0082 16.3 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) ThrE PF06738.12 KIK54678.1 - 0.0089 15.4 0.3 0.18 11.1 0.2 2.2 2 0 0 2 2 2 1 Putative threonine/serine exporter NPV_P10 PF05531.12 KIK54678.1 - 0.038 14.4 3.6 2.6 8.6 0.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KIK54678.1 - 0.042 14.1 1.9 5.4 7.3 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 KIK54678.1 - 0.054 13.3 1.9 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 KIK54678.1 - 0.06 13.7 3.5 1.5 9.2 0.5 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bet_v_1 PF00407.19 KIK54678.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family Syntaxin_2 PF14523.6 KIK54678.1 - 0.13 12.7 2.9 0.37 11.2 0.2 2.7 3 0 0 3 3 3 0 Syntaxin-like protein TPR_MLP1_2 PF07926.12 KIK54678.1 - 0.18 11.9 3.7 5.4 7.1 0.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.13 KIK54678.1 - 0.26 11.1 5.7 11 5.8 0.9 3.2 2 1 0 3 3 3 0 Nsp1-like C-terminal region FlaC_arch PF05377.11 KIK54678.1 - 0.31 11.4 1.5 5 7.6 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 KIK54678.1 - 0.34 11.1 3.6 1.5 9.1 1.2 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Spectrin PF00435.21 KIK54678.1 - 0.63 10.6 4.3 2.1 8.9 0.1 2.9 4 0 0 4 4 2 0 Spectrin repeat Laminin_II PF06009.12 KIK54678.1 - 0.77 9.8 3.2 11 6.0 0.2 2.8 2 1 0 2 2 2 0 Laminin Domain II KDZ PF18758.1 KIK54684.1 - 5.4e-22 78.5 3.4 5.8e-22 78.4 3.4 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase SR-25 PF10500.9 KIK54685.1 - 0.056 13.0 0.3 0.08 12.5 0.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein p450 PF00067.22 KIK54686.1 - 1.3e-28 100.0 0.3 8.2e-20 71.0 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 RE_Eco47II PF09553.10 KIK54686.1 - 0.061 12.9 0.0 1.4 8.4 0.0 2.5 2 1 1 3 3 3 0 Eco47II restriction endonuclease GPAT_N PF14829.6 KIK54686.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal p450 PF00067.22 KIK54687.1 - 5.3e-08 32.1 0.1 6.5e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Phage_NinH PF06322.11 KIK54687.1 - 0.24 11.3 0.7 12 5.9 0.3 2.4 1 1 1 2 2 2 0 Phage NinH protein p450 PF00067.22 KIK54688.1 - 4.1e-68 230.2 0.0 4.7e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIK54689.1 - 2.3e-49 168.4 0.0 3.5e-49 167.8 0.0 1.3 1 1 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIK54689.1 - 0.0011 18.3 0.3 1.1 8.4 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK54689.1 - 0.0038 16.5 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK54689.1 - 0.014 15.0 0.3 0.031 13.9 0.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK54689.1 - 0.021 15.1 0.2 0.096 12.9 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK54689.1 - 0.031 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK54689.1 - 0.058 12.5 0.2 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain LPP PF04728.13 KIK54690.1 - 0.47 10.9 11.8 0.92 9.9 0.8 3.9 4 0 0 4 4 4 0 Lipoprotein leucine-zipper BLOC1S3 PF15753.5 KIK54692.1 - 0.056 13.6 0.7 0.056 13.6 0.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 WRNPLPNID PF15017.6 KIK54692.1 - 1.4 9.8 14.2 12 6.9 7.5 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RPA43_OB PF17875.1 KIK54692.1 - 1.7 9.2 5.9 0.28 11.8 0.6 2.1 2 1 0 2 2 2 0 RPA43 OB domain in RNA Pol I S-antigen PF05756.11 KIK54695.1 - 0.22 11.9 4.2 2.8 8.4 0.4 2.3 2 0 0 2 2 2 0 S-antigen protein CAP_N PF01213.19 KIK54695.1 - 2.7 7.4 9.5 1.3 8.5 0.1 2.1 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DCAF15_WD40 PF14939.6 KIK54696.1 - 0.035 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Sigma70_ner PF04546.13 KIK54696.1 - 0.05 13.5 5.3 0.072 13.0 3.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region BSP_II PF05432.11 KIK54696.1 - 0.34 10.6 12.9 0.62 9.7 12.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF444 PF04285.12 KIK54696.1 - 0.49 9.4 6.4 0.42 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF444) CDC45 PF02724.14 KIK54696.1 - 7.3 4.8 11.5 12 4.0 11.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Pkip-1 PF06878.11 KIK54697.1 - 0.019 15.1 0.1 0.025 14.7 0.1 1.1 1 0 0 1 1 1 0 Pkip-1 protein DUF1744 PF08490.12 KIK54698.1 - 0.051 12.2 0.0 0.051 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) NPA PF16469.5 KIK54698.1 - 0.098 13.2 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Mitofilin PF09731.9 KIK54698.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-like PF04071.12 KIK54699.1 - 0.2 11.6 3.9 0.13 12.2 0.9 2.0 1 1 1 2 2 2 0 Cysteine-rich small domain WD40 PF00400.32 KIK54701.1 - 7.7e-151 485.4 57.9 1e-10 42.0 0.4 15.8 15 0 0 15 15 15 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54701.1 - 2.7e-38 130.1 16.8 0.13 12.6 0.0 15.1 1 1 14 15 15 15 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK54701.1 - 1.1e-26 93.9 10.7 0.00012 22.0 0.2 6.7 2 1 4 7 7 7 7 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK54701.1 - 1e-15 57.9 4.1 0.32 10.3 0.0 12.1 8 3 3 12 12 12 1 WD40-like domain Nup160 PF11715.8 KIK54701.1 - 1.7e-15 56.7 25.8 0.15 10.7 0.1 12.3 2 2 10 13 13 13 7 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK54701.1 - 3.6e-11 42.6 10.5 3.1 6.7 0.0 11.0 2 2 10 13 13 13 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK54701.1 - 2.1e-10 41.2 0.1 1e-08 35.8 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain nos_propeller PF18764.1 KIK54701.1 - 8.3e-10 38.4 25.8 6.1 6.8 0.1 12.2 11 1 2 13 13 13 2 Nitrous oxide reductase propeller repeat Goodbye PF17109.5 KIK54701.1 - 4.1e-08 33.7 0.0 2.9e-07 30.9 0.0 2.6 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KIK54701.1 - 7.9e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Imm17 PF15562.6 KIK54701.1 - 2.2e-05 24.2 0.0 78 3.2 0.0 7.8 9 1 1 10 10 9 0 Immunity protein 17 DsbC_N PF10411.9 KIK54701.1 - 0.00011 21.6 10.8 59 3.2 0.0 10.5 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus AAA PF00004.29 KIK54701.1 - 0.00064 20.1 4.7 0.0021 18.5 1.2 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NHL PF01436.21 KIK54701.1 - 0.0025 17.7 16.0 27 5.0 0.1 9.7 11 0 0 11 11 10 0 NHL repeat AAA_22 PF13401.6 KIK54701.1 - 0.0099 16.2 0.0 0.036 14.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KIK54701.1 - 0.011 14.9 0.0 0.035 13.3 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain GH115_C PF17829.1 KIK54701.1 - 0.053 13.4 4.0 0.93 9.3 0.1 3.5 3 0 0 3 3 3 0 Gylcosyl hydrolase family 115 C-terminal domain Zeta_toxin PF06414.12 KIK54701.1 - 0.056 12.7 0.0 0.17 11.1 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KIK54701.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF4019 PF13211.6 KIK54701.1 - 0.075 13.4 8.6 1.1e+02 3.3 0.0 7.9 8 1 1 9 9 9 0 Protein of unknown function (DUF4019) ResIII PF04851.15 KIK54701.1 - 0.13 12.2 0.7 0.4 10.7 0.7 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KIK54701.1 - 0.17 12.5 0.1 2.7 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK54701.1 - 1.1 8.4 4.0 4 6.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) EAP30 PF04157.16 KIK54702.1 - 1.3e-06 27.9 0.0 1.6e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family WD40 PF00400.32 KIK54703.1 - 1.7e-144 465.4 56.9 1.1e-10 41.9 0.3 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54703.1 - 8e-40 135.1 20.6 0.0049 17.1 0.1 13.4 2 2 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK54703.1 - 4.5e-26 91.9 9.9 1.7e-07 31.4 0.1 7.4 1 1 7 9 9 9 9 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK54703.1 - 1.3e-15 57.0 30.2 0.028 13.1 0.1 12.3 3 2 10 14 14 14 9 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK54703.1 - 2.6e-14 53.3 4.6 0.088 12.1 0.0 10.7 8 3 5 13 13 13 2 WD40-like domain Ge1_WD40 PF16529.5 KIK54703.1 - 6.7e-13 48.3 7.0 0.52 9.2 0.0 11.4 1 1 12 14 14 14 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK54703.1 - 2.2e-10 40.2 0.1 30 4.7 0.0 10.5 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK54703.1 - 1.5e-07 31.2 29.9 14 5.7 0.0 12.6 14 0 0 14 14 14 0 Nitrous oxide reductase propeller repeat DsbC_N PF10411.9 KIK54703.1 - 4.6e-07 29.2 6.1 65 3.1 0.0 10.6 13 0 0 13 13 13 0 Disulfide bond isomerase protein N-terminus potato_inhibit PF00280.18 KIK54703.1 - 4e-06 27.4 6.9 54 4.6 0.0 9.3 10 2 2 12 12 11 0 Potato inhibitor I family NHL PF01436.21 KIK54703.1 - 0.0016 18.4 13.4 18 5.6 0.0 9.3 10 0 0 10 10 10 0 NHL repeat HPS3_N PF14761.6 KIK54703.1 - 0.012 15.1 2.6 3.7 7.0 0.0 5.2 5 2 3 8 8 8 0 Hermansky-Pudlak syndrome 3 SdiA-regulated PF06977.11 KIK54703.1 - 0.12 11.5 0.0 61 2.7 0.0 4.4 2 2 4 7 7 7 0 SdiA-regulated Big_4 PF07532.11 KIK54703.1 - 2 8.2 31.5 14 5.5 0.1 9.3 11 0 0 11 11 10 0 Bacterial Ig-like domain (group 4) DUF4019 PF13211.6 KIK54703.1 - 2.2 8.7 12.3 24 5.4 0.0 7.2 8 2 1 10 10 9 0 Protein of unknown function (DUF4019) EAP30 PF04157.16 KIK54704.1 - 8.8e-35 120.1 0.0 1.2e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KIK54704.1 - 5.5e-12 45.7 0.0 9.3e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KIK54704.1 - 6.5e-05 22.2 4.9 0.0091 15.3 1.7 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KIK54704.1 - 0.0066 16.4 2.8 0.049 13.6 3.3 2.0 1 1 1 2 2 2 2 Double zinc ribbon Vps36-NZF-N PF16988.5 KIK54704.1 - 0.052 12.9 0.4 0.052 12.9 0.4 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KIK54704.1 - 0.12 12.4 5.7 3 7.9 0.6 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF3138 PF11336.8 KIK54704.1 - 10 4.6 8.9 0.3 9.7 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) E3_UbLigase_EDD PF11547.8 KIK54705.1 - 0.02 14.6 0.8 0.04 13.6 0.8 1.5 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Vpu PF00558.19 KIK54705.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 Vpu protein DUF3810 PF12725.7 KIK54705.1 - 0.51 9.6 1.8 0.48 9.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) HEAT PF02985.22 KIK54706.1 - 1.9e-17 61.9 0.0 0.00029 20.8 0.0 4.4 4 0 0 4 4 4 4 HEAT repeat Cnd1 PF12717.7 KIK54706.1 - 9.9e-14 51.7 0.1 1.8e-06 28.1 0.2 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK54706.1 - 1e-09 38.6 0.0 0.0018 18.7 0.0 2.6 1 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 KIK54706.1 - 1e-09 38.7 0.0 0.49 11.0 0.0 4.2 3 1 1 4 4 4 4 HEAT-like repeat Adaptin_N PF01602.20 KIK54706.1 - 1.4e-06 27.2 0.1 9.8e-06 24.4 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region MMS22L_C PF14911.6 KIK54706.1 - 3e-05 23.3 0.1 3.9e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal Vac14_Fab1_bd PF12755.7 KIK54706.1 - 0.0027 18.3 0.2 2.6 8.7 0.1 2.6 2 2 0 2 2 2 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 KIK54706.1 - 0.0036 17.3 0.1 2.2 8.4 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KIK54706.1 - 0.0038 16.8 0.0 1.4 8.4 0.0 2.5 1 1 1 2 2 2 2 CLASP N terminal Ecm29 PF13001.7 KIK54706.1 - 0.0082 14.9 2.4 5.3 5.6 0.0 3.0 2 1 1 3 3 3 2 Proteasome stabiliser Proteasom_PSMB PF10508.9 KIK54706.1 - 0.047 12.2 0.0 3.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Mod_r PF07200.13 KIK54706.1 - 0.053 13.6 2.0 0.72 9.9 1.5 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TetR_C_36 PF18598.1 KIK54706.1 - 0.054 13.4 0.0 0.69 9.9 0.0 2.5 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain OTT_1508_deam PF14441.6 KIK54707.1 - 0.00054 19.9 0.9 0.0013 18.7 0.9 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase EST1_DNA_bind PF10373.9 KIK54707.1 - 0.041 13.4 2.1 2.2 7.7 0.2 2.4 1 1 0 2 2 2 0 Est1 DNA/RNA binding domain EAP30 PF04157.16 KIK54708.1 - 1.6e-33 116.0 0.0 2.2e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KIK54708.1 - 5e-16 58.7 0.0 8.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KIK54708.1 - 5.7e-05 22.3 4.9 0.0084 15.4 1.7 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KIK54708.1 - 0.011 15.8 3.8 0.1 12.7 4.5 2.0 1 1 1 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 KIK54708.1 - 0.044 13.2 0.6 0.044 13.2 0.6 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KIK54708.1 - 0.1 12.6 5.7 2.8 8.1 0.6 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF3138 PF11336.8 KIK54708.1 - 0.62 8.6 3.5 1.2 7.6 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) YndJ PF14158.6 KIK54709.1 - 0.024 13.9 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 YndJ-like protein Ank_2 PF12796.7 KIK54710.1 - 1.6e-06 28.6 0.6 0.001 19.6 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK54710.1 - 0.0058 17.2 0.1 0.052 14.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK54710.1 - 0.0071 16.8 0.2 4.9 8.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KIK54710.1 - 0.023 15.1 0.9 10 6.8 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KIK54710.1 - 0.026 14.8 0.1 0.085 13.2 0.1 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) HEAT PF02985.22 KIK54711.1 - 5.3e-56 181.8 0.1 0.00021 21.3 0.0 12.2 12 0 0 12 12 12 11 HEAT repeat HEAT_EZ PF13513.6 KIK54711.1 - 9.4e-48 160.1 0.0 3e-05 24.4 0.0 10.7 11 1 0 11 11 10 9 HEAT-like repeat HEAT_2 PF13646.6 KIK54711.1 - 7.8e-41 138.4 0.0 1.2e-07 32.0 0.0 6.7 2 2 4 6 6 6 6 HEAT repeats Cnd1 PF12717.7 KIK54711.1 - 3.1e-39 134.6 7.9 3.6e-08 33.6 0.1 7.4 1 1 7 8 8 8 7 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KIK54711.1 - 1.2e-37 126.7 0.0 0.00079 19.4 0.0 11.1 12 0 0 12 12 11 8 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KIK54711.1 - 7.7e-29 100.6 0.5 2.2e-11 43.0 0.3 3.9 1 1 2 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.13 KIK54711.1 - 3.6e-21 75.8 11.1 5.8e-08 32.5 0.4 7.0 2 2 5 8 8 8 6 Armadillo-like Vac14_Fab1_bd PF12755.7 KIK54711.1 - 4.3e-11 43.2 7.3 0.013 16.0 0.0 7.1 1 1 5 7 7 7 3 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KIK54711.1 - 1.3e-10 41.4 4.1 0.097 12.9 0.0 6.0 1 1 4 6 6 6 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KIK54711.1 - 6.3e-10 39.0 1.7 0.014 15.0 0.3 6.0 1 1 2 4 4 4 2 CLASP N terminal TetR_C_36 PF18598.1 KIK54711.1 - 3.6e-09 36.6 0.0 1.7 8.7 0.0 7.6 3 2 7 10 10 9 1 Tetracyclin repressor-like, C-terminal domain V-ATPase_H_N PF03224.14 KIK54711.1 - 5.7e-09 35.7 13.6 0.0057 16.0 0.3 4.6 1 1 2 4 4 4 3 V-ATPase subunit H RasGEF_N_2 PF14663.6 KIK54711.1 - 1.3e-08 35.1 2.1 0.46 10.9 0.1 6.4 4 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_C PF11698.8 KIK54711.1 - 1.4e-08 34.8 4.4 0.27 11.3 0.0 6.3 2 2 5 7 7 7 2 V-ATPase subunit H Rcd1 PF04078.13 KIK54711.1 - 1.8e-08 34.0 0.8 0.14 11.4 0.0 6.0 2 2 4 6 6 6 1 Cell differentiation family, Rcd1-like Proteasom_PSMB PF10508.9 KIK54711.1 - 2.3e-08 33.0 4.4 0.063 11.8 0.0 4.3 2 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit IFRD PF05004.13 KIK54711.1 - 4.7e-08 32.5 0.4 0.94 8.5 0.0 6.5 2 2 5 7 7 7 1 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 KIK54711.1 - 1.5e-06 28.3 0.0 12 6.9 0.0 7.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Condensin2nSMC PF12422.8 KIK54711.1 - 5.5e-06 26.6 4.6 0.28 11.4 0.0 4.3 3 2 0 5 5 3 1 Condensin II non structural maintenance of chromosomes subunit Nipped-B_C PF12830.7 KIK54711.1 - 6.4e-06 26.2 0.0 0.1 12.6 0.0 4.2 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus DUF3546 PF12066.8 KIK54711.1 - 1.7e-05 25.0 8.4 8.5 6.6 0.0 7.5 4 3 4 9 9 8 0 Domain of unknown function (DUF3546) UME PF08064.13 KIK54711.1 - 4.3e-05 23.3 0.0 1 9.3 0.1 5.0 4 2 1 5 5 5 1 UME (NUC010) domain Gcn1_N PF12074.8 KIK54711.1 - 7.2e-05 22.2 0.0 12 5.0 0.0 4.9 2 2 3 5 5 5 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ecm29 PF13001.7 KIK54711.1 - 0.00063 18.5 10.3 0.0027 16.5 0.5 4.5 2 2 3 6 6 6 1 Proteasome stabiliser NUC173 PF08161.12 KIK54711.1 - 0.00064 19.4 5.6 2.4 7.8 0.1 5.5 2 1 4 7 7 7 1 NUC173 domain HycH PF07450.11 KIK54711.1 - 0.0008 19.8 0.2 2.6 8.5 0.0 4.4 2 2 5 7 7 6 1 Formate hydrogenlyase maturation protein HycH DUF4042 PF13251.6 KIK54711.1 - 0.0072 16.0 1.8 11 5.7 0.1 5.9 4 2 5 9 9 8 0 Domain of unknown function (DUF4042) BMFP PF04380.13 KIK54711.1 - 0.0075 16.7 1.8 67 4.1 0.0 6.3 7 1 1 8 8 7 0 Membrane fusogenic activity DUF3361 PF11841.8 KIK54711.1 - 0.015 15.2 2.3 7.5 6.5 0.0 4.6 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) Lip_A_acyltrans PF03279.13 KIK54711.1 - 0.021 14.0 0.3 50 2.9 0.0 4.3 3 2 2 5 5 5 0 Bacterial lipid A biosynthesis acyltransferase DUF1039 PF06287.11 KIK54711.1 - 0.022 15.2 0.1 17 5.9 0.0 4.5 4 2 1 5 5 3 0 Protein of unknown function (DUF1039) CTNNBL PF08216.11 KIK54711.1 - 0.036 14.2 1.3 6.6 7.0 0.1 4.3 4 2 2 6 6 4 0 Catenin-beta-like, Arm-motif containing nuclear DUF4058 PF13267.6 KIK54711.1 - 0.043 13.2 0.2 48 3.2 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4058) YebO PF13974.6 KIK54711.1 - 0.1 12.7 1.4 2.1 8.5 0.0 3.1 3 0 0 3 3 2 0 YebO-like protein EF-hand_like PF09279.11 KIK54711.1 - 0.12 12.8 3.9 2.4 8.7 0.1 4.5 3 2 2 5 5 4 0 Phosphoinositide-specific phospholipase C, efhand-like CAP_N PF01213.19 KIK54711.1 - 0.17 11.3 5.5 19 4.6 0.1 4.3 2 1 3 5 5 5 0 Adenylate cyclase associated (CAP) N terminal OSCP PF00213.18 KIK54711.1 - 0.32 11.1 8.6 5.1 7.2 0.1 5.0 1 1 2 5 5 5 0 ATP synthase delta (OSCP) subunit DUF3730 PF12530.8 KIK54711.1 - 0.35 10.4 4.2 30 4.1 0.4 3.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3730) DUF4209 PF13910.6 KIK54711.1 - 0.44 10.8 2.8 11 6.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) TPR_20 PF14561.6 KIK54711.1 - 0.64 10.4 4.4 6.2 7.2 0.0 4.3 3 3 3 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK54712.1 - 3e-106 344.8 33.0 2.6e-11 43.0 0.1 12.3 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54712.1 - 7.6e-92 301.7 78.4 4.4e-15 55.7 3.5 10.6 1 1 11 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 KIK54712.1 - 1.6e-13 49.7 32.1 0.03 14.3 0.1 11.5 12 1 0 12 12 12 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK54712.1 - 9.9e-10 38.3 27.9 6.6e-06 25.7 3.8 3.8 1 1 2 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 KIK54712.1 - 2.2e-07 30.5 40.5 0.063 13.4 0.1 11.2 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54712.1 - 9.4e-06 25.2 31.8 2.3 8.2 0.1 11.2 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK54712.1 - 3.8e-05 24.1 17.8 0.42 11.2 0.2 8.1 4 3 5 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK54712.1 - 0.00016 21.8 18.4 47 4.7 0.1 10.2 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK54712.1 - 0.00041 20.3 40.8 0.0017 18.4 0.0 9.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK54712.1 - 0.0006 20.4 13.3 7.2 7.4 0.1 7.2 5 2 3 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK54712.1 - 0.0034 17.9 3.4 1.8 9.4 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat Type_ISP_C PF18135.1 KIK54712.1 - 0.0067 15.5 0.5 2.8 6.8 0.1 3.0 3 0 0 3 3 3 1 Type ISP C-terminal specificity domain Gag_p30 PF02093.16 KIK54712.1 - 0.034 13.7 0.2 6.5 6.2 0.0 3.1 1 1 0 3 3 3 0 Gag P30 core shell protein IKBKB_SDD PF18397.1 KIK54712.1 - 0.051 12.9 2.6 2.9 7.1 0.1 3.6 2 1 2 4 4 4 0 IQBAL scaffold dimerization domain MCPVI PF02993.14 KIK54712.1 - 0.069 13.0 1.0 70 3.1 0.0 5.0 4 3 2 7 7 7 0 Minor capsid protein VI UBA_e1_thiolCys PF10585.9 KIK54712.1 - 0.18 11.7 0.7 1 9.2 0.3 2.4 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site DUF2777 PF10949.8 KIK54712.1 - 0.64 9.7 4.5 21 4.7 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2777) TPR_14 PF13428.6 KIK54712.1 - 7.4 7.7 19.2 8.8 7.5 0.1 7.0 7 1 1 8 8 7 0 Tetratricopeptide repeat HEAT_2 PF13646.6 KIK54713.1 - 8.2e-20 71.0 2.8 1.6e-05 25.2 0.5 4.2 1 1 4 5 5 5 5 HEAT repeats Arm PF00514.23 KIK54713.1 - 1.4e-19 69.4 0.0 0.0027 17.7 0.0 5.5 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KIK54713.1 - 2.8e-17 61.3 0.4 0.068 13.5 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 KIK54713.1 - 1.2e-15 57.9 3.4 9.4e-07 29.0 0.2 3.8 1 1 3 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIK54713.1 - 3.4e-12 45.7 0.8 7.3e-11 41.3 0.7 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.13 KIK54713.1 - 2.7e-08 33.6 2.4 1.2e-05 24.9 0.5 3.1 1 1 1 3 3 3 2 Armadillo-like HEAT_EZ PF13513.6 KIK54713.1 - 4.6e-08 33.4 1.4 0.1 13.2 0.0 5.4 4 2 2 6 6 6 2 HEAT-like repeat V-ATPase_H_N PF03224.14 KIK54713.1 - 3.8e-05 23.1 9.7 0.0011 18.4 2.1 2.7 1 1 1 2 2 2 2 V-ATPase subunit H RNase_T PF00929.24 KIK54713.1 - 0.00051 20.6 0.5 0.18 12.3 0.1 3.5 1 1 2 3 3 3 1 Exonuclease RTP1_C1 PF10363.9 KIK54713.1 - 0.0013 18.9 0.5 1.8 8.8 0.2 3.3 1 1 2 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KIK54713.1 - 0.0023 18.5 0.0 0.6 10.8 0.0 3.6 1 1 3 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KIK54713.1 - 0.028 14.0 1.4 18 4.8 0.1 3.4 1 1 2 3 3 3 0 CLASP N terminal APC_rep PF18797.1 KIK54713.1 - 0.051 14.5 0.2 1.9 9.4 0.0 3.3 3 0 0 3 3 3 0 Adenomatous polyposis coli (APC) repeat ERK-JNK_inhib PF15002.6 KIK54713.1 - 0.2 11.3 5.4 2.3 7.9 0.8 2.4 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor UvrD-helicase PF00580.21 KIK54713.1 - 0.61 9.6 7.8 2.4 7.6 7.8 1.8 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain TPR_10 PF13374.6 KIK54715.1 - 2.2e-161 520.1 53.0 7.2e-12 44.8 0.0 17.8 18 0 0 18 18 17 17 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54715.1 - 2.6e-141 460.2 80.5 9.3e-15 54.7 0.0 15.2 6 3 9 16 16 16 13 Tetratricopeptide repeat HEAT PF02985.22 KIK54715.1 - 7.2e-48 156.5 18.3 1.8e-05 24.6 0.0 12.0 11 0 0 11 11 11 10 HEAT repeat Cnd1 PF12717.7 KIK54715.1 - 1.4e-35 122.7 9.0 2.1e-10 40.9 0.3 5.5 1 1 4 5 5 5 5 non-SMC mitotic condensation complex subunit 1 TPR_MalT PF17874.1 KIK54715.1 - 1.2e-32 113.6 61.1 1.9e-11 43.9 4.6 8.1 2 2 6 9 9 9 7 MalT-like TPR region HEAT_2 PF13646.6 KIK54715.1 - 2.6e-31 107.9 20.2 1.5e-09 38.1 0.4 8.4 3 1 3 8 8 8 5 HEAT repeats TPR_7 PF13176.6 KIK54715.1 - 1.8e-30 102.7 42.9 0.061 13.4 0.0 18.7 18 0 0 18 18 18 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIK54715.1 - 2.6e-22 77.1 58.7 0.033 14.4 0.2 18.1 19 0 0 19 19 17 5 Tetratricopeptide repeat Arm PF00514.23 KIK54715.1 - 3.1e-22 77.9 15.8 0.00062 19.7 0.1 10.0 9 1 0 10 10 10 4 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KIK54715.1 - 3e-19 69.0 16.1 1.6e-06 27.0 1.0 5.4 2 1 4 6 6 6 5 Adaptin N terminal region TPR_1 PF00515.28 KIK54715.1 - 2.6e-18 65.0 64.6 0.029 14.2 0.0 19.6 21 0 0 21 21 20 5 Tetratricopeptide repeat HEAT_EZ PF13513.6 KIK54715.1 - 7.5e-18 64.6 20.7 1.8e-05 25.1 0.2 10.0 8 3 3 11 11 10 4 HEAT-like repeat TPR_2 PF07719.17 KIK54715.1 - 3.3e-15 54.9 62.9 0.15 12.3 0.2 17.7 20 0 0 20 20 17 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK54715.1 - 1.9e-12 46.6 39.5 5.4 7.6 0.1 16.7 18 0 0 18 18 17 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK54715.1 - 7.8e-12 44.6 47.0 1.3 9.9 0.2 14.1 15 0 0 15 15 13 3 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 KIK54715.1 - 1.2e-11 45.0 1.7 0.072 13.7 0.0 6.7 1 1 7 8 8 8 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KIK54715.1 - 3.1e-09 36.7 6.9 0.31 10.6 0.2 6.0 1 1 5 6 6 6 2 CLASP N terminal Arm_2 PF04826.13 KIK54715.1 - 4.7e-09 36.1 8.3 0.02 14.4 0.1 5.4 3 1 0 4 4 4 3 Armadillo-like TPR_14 PF13428.6 KIK54715.1 - 5e-06 26.9 46.0 1.4 9.9 0.1 15.0 13 4 5 18 18 14 2 Tetratricopeptide repeat DUF5071 PF16804.5 KIK54715.1 - 1.4e-05 25.3 7.3 0.37 11.1 0.0 5.5 3 2 2 5 5 5 1 Domain of unknown function (DUF5071) TPR_19 PF14559.6 KIK54715.1 - 3.9e-05 24.1 68.0 0.084 13.4 0.2 14.4 6 3 13 19 19 17 4 Tetratricopeptide repeat TPR_3 PF07720.12 KIK54715.1 - 0.00011 22.1 41.4 5.7 7.0 0.1 12.4 14 0 0 14 14 12 0 Tetratricopeptide repeat TFCD_C PF12612.8 KIK54715.1 - 0.00022 21.1 11.8 0.14 12.0 0.4 4.9 2 1 4 6 6 5 2 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 KIK54715.1 - 0.00029 21.0 14.7 0.25 11.5 0.1 6.3 5 1 1 6 6 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF806 PF05657.11 KIK54715.1 - 0.0014 19.1 5.3 0.41 11.1 0.1 4.8 4 2 1 5 5 4 1 Protein of unknown function (DUF806) RPN7 PF10602.9 KIK54715.1 - 0.0017 18.1 11.7 3.1 7.5 0.1 7.9 7 2 2 10 10 9 1 26S proteasome subunit RPN7 UME PF08064.13 KIK54715.1 - 0.0037 17.1 0.7 1.1 9.2 0.1 3.9 2 1 1 3 3 3 1 UME (NUC010) domain Ribosomal_60s PF00428.19 KIK54715.1 - 0.0067 17.0 2.7 25 5.5 0.1 5.2 4 1 1 5 5 5 0 60s Acidic ribosomal protein DUF5517 PF17639.2 KIK54715.1 - 0.02 15.1 1.3 21 5.5 0.0 4.9 4 1 0 4 4 4 0 Family of unknown function (DUF5517) RasGEF_N_2 PF14663.6 KIK54715.1 - 0.025 15.0 15.0 23 5.4 0.2 6.4 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3646 PF12362.8 KIK54715.1 - 0.039 14.3 3.8 12 6.3 0.0 4.3 3 1 1 4 4 4 0 DNA polymerase III gamma and tau subunits C terminal ASL_C PF08328.11 KIK54715.1 - 0.051 13.7 10.4 0.57 10.3 0.1 5.6 4 2 1 6 6 5 0 Adenylosuccinate lyase C-terminal TPR_16 PF13432.6 KIK54715.1 - 0.065 13.9 61.5 2.7 8.7 0.0 15.0 10 6 6 17 17 16 0 Tetratricopeptide repeat YgbB PF02542.16 KIK54715.1 - 0.07 13.4 0.8 1.9 8.8 0.1 3.5 2 2 3 5 5 2 0 YgbB family BMFP PF04380.13 KIK54715.1 - 0.64 10.5 8.2 48 4.5 0.2 6.1 5 1 1 6 6 4 0 Membrane fusogenic activity HisKA_3 PF07730.13 KIK54715.1 - 6.7 7.3 9.3 21 5.7 0.0 6.1 6 2 1 7 7 3 0 Histidine kinase COMP PF11598.8 KIK54715.1 - 7.6 7.1 8.0 17 6.0 0.1 4.6 5 0 0 5 5 3 0 Cartilage oligomeric matrix protein Aconitase PF00330.20 KIK54717.1 - 1.5e-103 347.3 0.5 1.9e-102 343.6 0.5 2.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK54717.1 - 1e-21 77.7 0.0 8.6e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Aconitase C-terminal domain STE PF02200.16 KIK54718.1 - 7.4e-54 180.9 0.0 1.2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KIK54718.1 - 2e-07 31.1 6.8 0.0022 18.4 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK54718.1 - 0.00026 21.6 8.2 0.015 16.1 2.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK54718.1 - 0.0021 18.4 2.1 0.0021 18.4 2.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIK54718.1 - 0.0085 16.4 0.1 0.0085 16.4 0.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 KIK54718.1 - 0.076 13.5 0.5 0.21 12.1 0.5 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1687 PF07955.11 KIK54719.1 - 5e-19 69.0 0.0 6.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Cauli_DNA-bind PF03310.13 KIK54719.1 - 0.15 12.1 0.2 0.97 9.5 0.1 2.1 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein LRR_4 PF12799.7 KIK54720.1 - 0.0025 18.2 0.1 6.5 7.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 KIK54722.1 - 0.055 13.3 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair F-box-like PF12937.7 KIK54723.1 - 1.1e-06 28.4 0.5 8e-06 25.7 0.5 2.5 1 1 0 1 1 1 1 F-box-like Rhodanese PF00581.20 KIK54724.1 - 2.5e-08 34.4 0.0 6e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Pkinase_Tyr PF07714.17 KIK54725.1 - 9.3e-07 28.4 0.0 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK54725.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54726.1 - 1.3e-25 90.1 0.0 1.5e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK54726.1 - 5.4e-20 71.9 0.0 6.6e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK54726.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK54728.1 - 4.8e-21 75.2 0.0 6.6e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK54728.1 - 5.1e-17 62.1 0.0 7.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK54728.1 - 0.028 14.3 1.5 0.048 13.6 0.2 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family STE PF02200.16 KIK54729.1 - 1.2e-53 180.1 0.0 1.6e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 STE like transcription factor DUF21 PF01595.20 KIK54731.1 - 1.6e-34 119.2 0.4 2.4e-34 118.5 0.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Mak16 PF04874.14 KIK54731.1 - 0.036 14.7 1.2 0.064 13.9 1.2 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region Nucleo_P87 PF07267.11 KIK54731.1 - 3.3 6.4 4.4 4.8 5.9 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Septin PF00735.18 KIK54736.1 - 3.9e-111 370.8 0.1 5.1e-111 370.5 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIK54736.1 - 1.8e-07 31.3 0.0 4.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK54736.1 - 5e-07 29.8 0.4 4e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KIK54736.1 - 5e-06 26.2 0.4 0.00073 19.1 0.0 2.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK54736.1 - 0.00029 21.0 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK54736.1 - 0.0008 19.8 0.1 0.0043 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK54736.1 - 0.001 19.3 1.3 0.0042 17.4 0.1 2.5 2 2 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KIK54736.1 - 0.0021 17.8 0.2 0.13 12.0 0.2 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 KIK54736.1 - 0.0028 17.0 0.0 0.0064 15.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIK54736.1 - 0.0063 17.0 0.1 0.018 15.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 KIK54736.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 KIK54736.1 - 0.017 14.8 0.1 0.053 13.1 0.1 1.9 1 1 0 1 1 1 0 Ras family AAA_24 PF13479.6 KIK54736.1 - 0.028 14.2 0.2 0.07 12.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK54736.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIK54736.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 KIK54736.1 - 0.11 12.6 6.1 1.2 9.2 0.1 2.8 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 KIK54736.1 - 0.14 11.6 0.1 0.53 9.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KIK54736.1 - 0.15 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KIK54736.1 - 0.21 11.1 0.7 0.49 9.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KIK54736.1 - 0.26 11.7 1.3 2.2 8.7 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KIK54736.1 - 0.36 10.6 3.1 7.4 6.3 0.4 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein FAS_meander PF17951.1 KIK54737.1 - 0.00047 20.0 0.6 0.0011 18.9 0.6 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain PsbX PF06596.11 KIK54739.1 - 1.1 9.3 5.1 1.5 8.9 1.0 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DHHC PF01529.20 KIK54739.1 - 5.6 7.1 15.8 0.74 9.9 5.2 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase CLP1_P PF16575.5 KIK54740.1 - 4.1e-28 98.5 0.0 9.6e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 KIK54740.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIK54740.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TMEM171 PF15471.6 KIK54740.1 - 0.29 10.1 1.3 0.57 9.1 1.3 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 CNDH2_C PF16858.5 KIK54741.1 - 0.016 15.1 0.3 0.018 15.0 0.3 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term adh_short PF00106.25 KIK54742.1 - 3.3e-43 147.4 0.1 4.4e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54742.1 - 2.3e-41 141.9 0.3 2.9e-41 141.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK54742.1 - 0.0008 19.4 0.6 0.0021 18.0 0.6 1.7 1 1 1 2 2 2 1 KR domain Tmemb_170 PF10190.9 KIK54743.1 - 0.072 13.5 6.4 2.6 8.5 5.8 2.0 1 1 1 2 2 2 0 Putative transmembrane protein 170 MSP1b PF03429.13 KIK54743.1 - 0.49 8.4 3.5 0.5 8.4 3.5 1.0 1 0 0 1 1 1 0 Major surface protein 1B SseC PF04888.12 KIK54743.1 - 1.5 8.4 4.4 1.4 8.4 4.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Choline_sulf_C PF12411.8 KIK54744.1 - 0.15 11.8 0.7 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal CPSase_L_D2 PF02786.17 KIK54750.1 - 4.7e-116 385.7 0.4 2.9e-83 278.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KIK54750.1 - 9.4e-49 164.5 0.0 2.4e-48 163.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIK54750.1 - 7.3e-48 162.9 0.0 6.7e-46 156.5 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KIK54750.1 - 3.7e-46 156.8 0.0 7.7e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KIK54750.1 - 8.7e-40 135.9 0.1 2.2e-39 134.6 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KIK54750.1 - 1.1e-31 110.0 0.0 1.2e-30 106.6 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KIK54750.1 - 9.6e-20 71.0 0.4 1.2e-09 38.0 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 KIK54750.1 - 4.2e-17 62.1 0.0 1.8e-16 60.1 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KIK54750.1 - 2.3e-16 59.9 0.3 4.4e-08 32.9 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIK54750.1 - 1.5e-09 37.7 0.1 0.00055 19.7 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KIK54750.1 - 5.9e-06 26.2 0.4 0.0005 19.9 0.0 2.8 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 KIK54750.1 - 5.6e-05 23.3 0.4 0.11 12.5 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 KIK54750.1 - 0.0006 19.5 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 KIK54750.1 - 0.00066 19.5 0.0 0.62 9.8 0.0 4.5 6 0 0 6 6 5 1 DJ-1/PfpI family GARS_A PF01071.19 KIK54750.1 - 0.011 15.5 0.1 0.66 9.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KIK54750.1 - 0.12 11.9 0.0 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 ATP-grasp domain NACHT PF05729.12 KIK54752.1 - 1.3e-10 41.4 0.0 2.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK54752.1 - 1.7e-06 28.5 0.2 3.2e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK54752.1 - 0.00081 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KIK54752.1 - 0.0023 17.3 0.1 0.31 10.2 0.0 2.1 2 0 0 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.22 KIK54752.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KIK54752.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK54752.1 - 0.067 12.4 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KIK54752.1 - 0.097 13.1 0.0 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KIK54752.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KIK54752.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Glycogen_syn PF05693.13 KIK54753.1 - 0 1101.4 0.0 0 1101.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 KIK54753.1 - 4.7e-07 29.8 0.1 1.6e-06 28.0 0.1 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 KIK54753.1 - 1.4e-06 28.7 0.0 0.0013 19.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIK54753.1 - 1.6e-06 27.8 0.0 0.00032 20.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIK54753.1 - 4.6e-05 23.5 0.3 8.6e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIK54753.1 - 5.1e-05 23.8 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ALO PF04030.14 KIK54755.1 - 4.8e-08 33.1 4.8 2.1e-07 31.0 4.8 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK54755.1 - 6e-08 32.5 0.0 4.5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Chol_subst-bind PF09129.11 KIK54755.1 - 0.00029 19.9 6.4 0.002 17.2 1.4 2.9 2 1 0 2 2 2 2 Cholesterol oxidase, substrate-binding Gln-synt_N_2 PF16952.5 KIK54755.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain TPR_2 PF07719.17 KIK54756.1 - 5e-06 26.2 5.6 0.034 14.2 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54756.1 - 0.0013 18.4 1.9 0.26 11.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK54756.1 - 0.11 13.4 0.5 2.3 9.3 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Defensin_2 PF01097.18 KIK54756.1 - 2.3 8.2 6.8 0.47 10.4 3.3 1.7 2 0 0 2 2 2 0 Arthropod defensin TPR_16 PF13432.6 KIK54756.1 - 4.3 8.1 7.1 2.6 8.8 2.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_S9 PF00326.21 KIK54757.1 - 1.5e-40 138.9 0.0 2.6e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KIK54757.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KIK54757.1 - 2.2e-06 27.7 0.0 2.2e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK54757.1 - 0.00018 20.8 0.0 0.0041 16.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DPPIV_N PF00930.21 KIK54757.1 - 0.00036 19.4 0.0 0.55 8.9 0.0 2.9 3 0 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_4 PF08386.10 KIK54757.1 - 0.004 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein PD40 PF07676.12 KIK54757.1 - 0.017 15.0 2.5 0.047 13.7 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 KIK54757.1 - 0.028 14.1 0.0 0.091 12.4 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIK54757.1 - 0.059 13.2 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 KIK54757.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hist_deacetyl PF00850.19 KIK54758.1 - 2.1e-80 270.5 0.0 2.8e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SOG2 PF10428.9 KIK54758.1 - 0.24 10.5 13.0 0.35 10.0 13.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KIK54758.1 - 5.3 6.8 13.6 9.9 6.0 13.6 1.4 1 0 0 1 1 1 0 SPX domain F-box-like PF12937.7 KIK54760.1 - 2.2e-06 27.5 1.3 6e-06 26.1 1.3 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KIK54761.1 - 8.2e-39 133.5 35.9 8.2e-39 133.5 35.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK54761.1 - 1.3e-15 57.3 6.1 1.3e-15 57.3 6.1 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KIK54761.1 - 3.9e-05 22.2 1.7 3.9e-05 22.2 1.7 3.3 1 1 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Hydrophobin PF01185.18 KIK54762.1 - 1.7e-14 54.2 9.1 2.3e-14 53.8 9.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Tubulin PF00091.25 KIK54763.1 - 9.7e-69 231.5 0.0 2e-68 230.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK54763.1 - 6.9e-42 142.6 0.1 1.1e-41 141.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIK54763.1 - 3.3e-07 30.6 0.1 1e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KIK54763.1 - 0.0024 17.1 0.0 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KIK54763.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Sugar_tr PF00083.24 KIK54764.1 - 1.2e-108 363.9 28.5 1.4e-108 363.7 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK54764.1 - 1.7e-22 79.9 41.8 1.5e-21 76.8 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5090 PF17009.5 KIK54765.1 - 0.5 10.3 3.6 0.56 10.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) adh_short PF00106.25 KIK54767.1 - 4.9e-37 127.3 0.6 5.4e-36 123.9 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54767.1 - 9.1e-34 117.0 2.2 3e-33 115.3 2.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK54767.1 - 5.1e-08 33.0 0.4 1.3e-06 28.5 0.1 2.2 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KIK54767.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK54767.1 - 0.0029 17.1 0.2 0.0055 16.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK54767.1 - 0.019 15.3 0.5 0.098 12.9 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 KIK54767.1 - 0.16 11.7 0.6 0.35 10.7 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 KIK54767.1 - 1 8.7 3.6 14 4.9 0.0 2.3 1 1 1 2 2 2 0 ThiF family adh_short PF00106.25 KIK54769.1 - 2.5e-46 157.6 0.1 3.3e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK54769.1 - 2.2e-44 151.8 0.3 2.6e-44 151.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK54769.1 - 5.7e-10 39.4 0.3 8.5e-10 38.8 0.3 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KIK54769.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK54769.1 - 0.00036 20.1 0.1 0.00078 19.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK54769.1 - 0.05 13.9 0.2 0.097 12.9 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 KIK54769.1 - 0.072 12.9 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 KIK54769.1 - 0.08 12.3 3.7 0.88 8.9 0.0 2.2 1 1 1 2 2 2 0 ThiF family Ldh_1_N PF00056.23 KIK54769.1 - 0.093 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F-box-like PF12937.7 KIK54770.1 - 0.00043 20.1 0.8 0.0014 18.4 0.0 2.4 3 0 0 3 3 3 1 F-box-like DUF5090 PF17009.5 KIK54771.1 - 1.1 9.2 16.4 0.099 12.6 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) Peptidase_S9 PF00326.21 KIK54773.1 - 2.7e-37 128.3 0.0 4.5e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK54773.1 - 8.3e-07 28.5 0.0 1.6e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KIK54773.1 - 2.6e-06 27.1 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KIK54773.1 - 5.4e-05 23.1 0.0 0.00043 20.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KIK54773.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KIK54773.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KIK54773.1 - 0.014 15.0 0.0 0.086 12.5 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Curto_V3 PF07436.11 KIK54773.1 - 0.085 13.3 0.0 0.38 11.2 0.0 2.1 3 0 0 3 3 3 0 Curtovirus V3 protein Peptidase_S15 PF02129.18 KIK54773.1 - 0.092 12.3 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Questin_oxidase PF14027.6 KIK54774.1 - 1.9e-81 274.3 0.0 2.7e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Wbp11 PF09429.10 KIK54774.1 - 0.03 14.7 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 DUF4795 PF16043.5 KIK54774.1 - 0.21 11.2 0.1 0.84 9.2 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) HA2 PF04408.23 KIK54776.1 - 9.2e-23 80.6 0.1 1.8e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK54776.1 - 1.7e-20 73.1 0.0 3.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KIK54777.1 - 5.4e-21 74.9 0.1 5.4e-21 74.9 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK54777.1 - 7.3e-21 74.3 0.0 2.3e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK54777.1 - 1e-10 41.9 0.0 5.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK54777.1 - 6.7e-08 32.5 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK54777.1 - 1.2e-05 25.7 0.1 4.1e-05 23.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KIK54777.1 - 4.3e-05 23.9 0.1 0.00011 22.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KIK54777.1 - 0.00023 20.9 0.2 0.00094 18.9 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KIK54777.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIK54777.1 - 0.0027 17.4 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK54777.1 - 0.0065 15.6 0.0 0.023 13.8 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KIK54777.1 - 0.013 15.5 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 KIK54777.1 - 0.013 15.5 0.3 0.56 10.2 0.1 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK54777.1 - 0.018 15.6 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KIK54777.1 - 0.056 13.9 0.3 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK54777.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIK54777.1 - 0.098 12.7 0.0 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KIK54777.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KIK54777.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF913 PF06025.12 KIK54777.1 - 0.2 10.6 1.5 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pex14_N PF04695.13 KIK54777.1 - 0.28 11.8 3.2 0.78 10.4 3.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC106 PF15794.5 KIK54777.1 - 7.4 6.2 10.0 15 5.3 10.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BCS1_N PF08740.11 KIK54778.1 - 1.3e-41 142.6 2.4 2.3e-41 141.8 1.9 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KIK54778.1 - 1.1e-15 58.2 0.0 4.2e-07 30.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIK54778.1 - 7e-05 22.1 0.0 0.00017 20.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIK54778.1 - 0.0058 16.4 1.5 0.021 14.6 0.0 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK54778.1 - 0.05 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KIK54778.1 - 0.061 13.8 0.2 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 KIK54778.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KIK54778.1 - 0.3 11.6 3.0 0.64 10.6 0.0 2.7 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KIK54778.1 - 0.37 11.2 6.9 0.55 10.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain IcmF-related PF06761.12 KIK54778.1 - 0.54 9.7 5.8 0.45 9.9 2.7 2.0 2 0 0 2 2 2 0 Intracellular multiplication and human macrophage-killing AhpC-TSA PF00578.21 KIK54780.1 - 3.2e-24 85.2 0.0 4e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KIK54780.1 - 3.1e-11 42.9 0.0 6.4e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KIK54780.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin PS_Dcarbxylase PF02666.15 KIK54783.1 - 1.1e-59 201.4 0.0 1.8e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KIK54783.1 - 2.3e-30 104.9 0.0 1.3e-18 67.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 KIK54783.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KIK54783.1 - 0.15 12.1 0.1 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain Smac_DIABLO PF09057.10 KIK54783.1 - 1.9 7.8 3.9 4.2 6.7 3.9 1.5 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases BTB PF00651.31 KIK54785.1 - 0.0018 18.5 0.0 0.013 15.7 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain AmiS_UreI PF02293.15 KIK54788.1 - 0.037 14.0 1.1 0.044 13.8 1.1 1.1 1 0 0 1 1 1 0 AmiS/UreI family transporter Cauli_VI PF01693.16 KIK54790.1 - 0.00012 22.3 0.2 0.00022 21.5 0.2 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin Retrotrans_gag PF03732.17 KIK54793.1 - 4e-09 36.6 0.6 4e-09 36.6 0.6 1.9 2 1 0 2 2 2 1 Retrotransposon gag protein QH-AmDH_gamma PF08992.11 KIK54793.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit DUF5623 PF18536.1 KIK54795.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) zf-C3HC4_5 PF17121.5 KIK54795.1 - 2.4 8.1 6.7 6.7 6.7 0.1 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M10 PF00413.24 KIK54798.1 - 0.017 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Matrixin Helitron_like_N PF14214.6 KIK54799.1 - 1.1e-17 64.9 0.0 1.3e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4313 PF14190.6 KIK54800.1 - 0.055 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Retrotran_gag_2 PF14223.6 KIK54801.1 - 4e-20 71.9 0.0 5.9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1424 PF07232.11 KIK54801.1 - 0.0058 15.7 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative rep protein (DUF1424) TPR_10 PF13374.6 KIK54802.1 - 1e-69 228.7 2.4 3.4e-09 36.3 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54802.1 - 2e-63 210.6 18.6 5.2e-10 39.5 0.0 8.2 1 1 8 9 9 9 9 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK54802.1 - 6.1e-10 39.1 0.1 0.42 10.7 0.0 7.0 3 2 4 7 7 7 1 Rapsyn N-terminal myristoylation and linker region TPR_19 PF14559.6 KIK54802.1 - 6.7e-08 32.9 5.6 0.13 12.8 0.1 6.2 3 2 3 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK54802.1 - 2e-07 31.1 7.8 0.039 14.2 0.0 5.9 5 1 2 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIK54802.1 - 4.7e-07 29.4 27.7 2.1 8.6 0.1 9.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK54802.1 - 1e-06 28.3 21.3 0.21 11.7 0.0 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54802.1 - 2.1e-06 27.3 26.8 0.3 11.0 0.2 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat PPR PF01535.20 KIK54802.1 - 3.5e-05 23.8 0.6 35 4.9 0.0 6.9 7 0 0 7 7 7 0 PPR repeat RPN7 PF10602.9 KIK54802.1 - 0.00014 21.6 0.3 0.93 9.2 0.0 4.2 3 2 0 3 3 3 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 KIK54802.1 - 0.00017 21.7 1.8 0.89 9.7 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KIK54802.1 - 0.0002 21.5 0.3 14 5.7 0.1 5.0 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 KIK54802.1 - 0.00032 20.7 0.1 25 4.9 0.0 5.7 2 1 4 6 6 6 0 Putative TPR-like repeat TPR_8 PF13181.6 KIK54802.1 - 0.00039 20.4 14.0 2.6 8.5 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Zincin_2 PF10103.9 KIK54802.1 - 0.00066 19.0 0.0 1.6 7.9 0.0 3.0 2 1 0 2 2 2 2 Zincin-like metallopeptidase DUF2664 PF10867.8 KIK54802.1 - 0.0016 18.8 0.8 4.6 7.8 0.0 5.0 6 0 0 6 6 4 1 Protein of unknown function (DUF2664) TPR_16 PF13432.6 KIK54802.1 - 0.0034 18.0 4.5 75 4.1 0.0 6.0 6 1 0 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 KIK54802.1 - 0.0041 17.6 4.9 15 6.0 0.5 5.2 2 2 2 5 5 5 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KIK54802.1 - 0.029 15.0 4.1 56 4.7 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK54802.1 - 0.034 14.7 0.0 1.3e+02 3.6 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK54802.1 - 0.11 12.9 15.6 6.1 7.5 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_16 PF13191.6 KIK54804.1 - 0.018 15.4 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Mlf1IP PF10248.9 KIK54804.1 - 0.068 13.1 1.3 0.089 12.8 1.3 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein TrwB_AAD_bind PF10412.9 KIK54804.1 - 0.2 10.5 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KIK54804.1 - 0.23 10.6 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TPR_10 PF13374.6 KIK54806.1 - 1.4e-71 234.6 1.5 1.3e-08 34.4 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54806.1 - 1.1e-54 182.6 13.5 9.6e-11 41.8 0.1 7.8 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KIK54806.1 - 1.2e-11 43.7 15.0 0.93 9.7 0.0 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK54806.1 - 8.3e-08 32.2 1.0 0.81 9.8 0.0 7.6 6 2 4 10 10 9 1 Rapsyn N-terminal myristoylation and linker region ANAPC3 PF12895.7 KIK54806.1 - 7e-07 29.4 1.8 0.62 10.3 0.0 5.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK54806.1 - 1.2e-06 28.9 2.9 1.7 9.2 0.0 5.8 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54806.1 - 4.5e-06 26.2 21.8 0.6 10.0 0.2 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat Zincin_2 PF10103.9 KIK54806.1 - 9.5e-06 25.1 0.3 0.26 10.5 0.3 3.0 2 1 0 2 2 2 2 Zincin-like metallopeptidase TPR_17 PF13431.6 KIK54806.1 - 8.8e-05 22.6 6.8 7.9 7.1 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK54806.1 - 9.7e-05 22.9 1.0 7.2 7.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK54806.1 - 0.00023 21.5 0.1 1e+02 4.0 0.0 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK54806.1 - 0.00049 20.0 27.3 6.1 7.2 0.1 9.6 11 0 0 11 11 10 2 Tetratricopeptide repeat DUF3856 PF12968.7 KIK54806.1 - 0.001 19.1 1.6 12 6.0 0.0 5.6 1 1 3 5 5 5 0 Domain of Unknown Function (DUF3856) NB-ARC PF00931.22 KIK54806.1 - 0.0012 18.1 0.4 0.025 13.8 0.4 2.4 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KIK54806.1 - 0.0014 19.2 0.7 41 5.4 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 KIK54806.1 - 0.0022 18.5 2.5 2.6 8.5 0.4 4.3 3 1 2 5 5 4 1 Bacterial transcriptional activator domain TPR_8 PF13181.6 KIK54806.1 - 0.0025 17.9 14.1 19 5.8 0.0 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK54806.1 - 0.033 14.4 0.5 19 5.5 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KIK54806.1 - 0.046 14.0 4.0 2.7e+02 2.2 0.0 6.2 7 0 0 7 7 5 0 PPR repeat AAA_16 PF13191.6 KIK54806.1 - 0.058 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK54806.1 - 0.064 13.5 0.0 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF480 PF04337.12 KIK54806.1 - 0.11 12.6 0.3 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF480 DUF2664 PF10867.8 KIK54806.1 - 0.57 10.7 1.9 32 5.1 0.1 4.5 6 1 1 7 7 5 0 Protein of unknown function (DUF2664) TPR_6 PF13174.6 KIK54806.1 - 1.2 9.9 2.9 1.4e+02 3.5 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Aldedh PF00171.22 KIK54807.1 - 8.6e-71 238.8 0.0 1e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KIK54808.1 - 6.7e-40 137.1 57.3 6.7e-40 137.1 57.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK54808.1 - 0.0028 16.6 30.2 0.0066 15.4 9.3 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter HRG PF16954.5 KIK54808.1 - 1.5 9.3 12.7 17 5.9 2.3 4.4 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene F-box-like PF12937.7 KIK54809.1 - 7.1e-05 22.6 1.2 7.1e-05 22.6 1.2 2.3 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 KIK54809.1 - 0.47 10.1 1.9 0.87 9.2 0.5 2.1 2 0 0 2 2 2 0 F-box Cupin_1 PF00190.22 KIK54810.1 - 4e-29 101.2 0.1 2e-20 72.9 0.0 3.2 2 1 1 3 3 3 3 Cupin Cupin_2 PF07883.11 KIK54810.1 - 1.4e-16 60.0 0.1 6.6e-12 45.0 0.0 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KIK54810.1 - 1.6e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK54810.1 - 0.00084 19.0 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 KIK54810.1 - 0.0038 17.4 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 ARD/ARD' family DUF2475 PF10629.9 KIK54810.1 - 0.022 14.9 0.0 0.071 13.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) MannoseP_isomer PF01050.18 KIK54810.1 - 0.024 14.6 0.0 7.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase 3-HAO PF06052.12 KIK54810.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase cNMP_binding PF00027.29 KIK54810.1 - 0.18 11.9 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain F-box-like PF12937.7 KIK54811.1 - 8.7e-08 31.9 0.7 2.1e-07 30.7 0.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK54811.1 - 0.00015 22.1 1.0 0.026 15.0 0.2 3.8 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK54811.1 - 0.26 11.2 4.1 2.1 8.3 4.1 2.5 1 1 0 1 1 1 0 F-box domain Cupin_1 PF00190.22 KIK54812.1 - 2.2e-37 128.0 0.3 5.5e-21 74.7 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KIK54812.1 - 3.4e-23 81.1 0.1 1.2e-12 47.3 0.0 3.1 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KIK54812.1 - 4.3e-07 29.9 0.0 9.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK54812.1 - 3.2e-05 23.5 0.0 0.00091 18.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) ARD PF03079.14 KIK54812.1 - 0.0022 18.2 0.0 0.0084 16.3 0.0 1.9 3 0 0 3 3 3 1 ARD/ARD' family MannoseP_isomer PF01050.18 KIK54812.1 - 0.004 17.0 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.12 KIK54812.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase F-box-like PF12937.7 KIK54814.1 - 8.6e-06 25.6 0.1 3.1e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK54814.1 - 0.07 13.0 3.6 0.49 10.3 0.0 2.7 2 0 0 2 2 2 0 F-box domain MR_MLE_C PF13378.6 KIK54816.1 - 3.1e-47 161.0 0.4 3.4e-46 157.6 0.4 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIK54816.1 - 5.6e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KIK54816.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Peptidase_C25_C PF03785.14 KIK54816.1 - 0.048 13.5 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain p450 PF00067.22 KIK54817.1 - 3.3e-52 177.8 0.0 3.8e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54818.1 - 6.7e-55 186.7 0.0 8.7e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3_C PF01915.22 KIK54819.1 - 2.4e-46 158.3 0.0 4.3e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIK54819.1 - 5.6e-22 77.6 0.0 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KIK54819.1 - 4e-18 65.9 0.0 1.4e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain GFO_IDH_MocA PF01408.22 KIK54820.1 - 1.1e-11 45.6 0.4 2e-11 44.7 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK54820.1 - 0.0017 18.4 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KIK54820.1 - 0.0084 16.7 0.0 0.0084 16.7 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_6 PF01341.17 KIK54820.1 - 0.049 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 Fn3-like PF14310.6 KIK54821.1 - 4.6e-24 84.3 0.0 5.7e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 KIK54821.1 - 0.11 12.7 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 CARDB GFO_IDH_MocA PF01408.22 KIK54822.1 - 2e-11 44.8 0.1 4e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KIK54822.1 - 0.0028 18.2 0.4 0.0085 16.7 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_6 PF01341.17 KIK54822.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 GFO_IDH_MocA_C PF02894.17 KIK54822.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Taeniidae_ag PF05596.11 KIK54822.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen GFO_IDH_MocA PF01408.22 KIK54823.1 - 1.9e-11 44.8 0.1 3.7e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_6 PF01341.17 KIK54823.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 F420_oxidored PF03807.17 KIK54823.1 - 0.03 14.9 0.0 0.082 13.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3530 PF12048.8 KIK54823.1 - 0.085 12.3 0.1 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF3328 PF11807.8 KIK54824.1 - 3e-18 66.4 0.2 3.3e-18 66.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KIK54825.1 - 7.4e-18 65.1 2.9 2.5e-17 63.4 2.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Aminotran_4 PF01063.19 KIK54829.1 - 8.9e-30 104.2 0.0 1.9e-29 103.1 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV zf-MYND PF01753.18 KIK54830.1 - 3.7e-08 33.3 11.6 7.4e-08 32.4 11.6 1.5 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.6 KIK54832.1 - 5.9e-158 509.2 7.3 4.4e-14 51.8 0.1 13.1 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK54832.1 - 1.8e-109 358.2 16.4 1.9e-13 50.5 0.1 12.4 1 1 11 12 12 12 12 Tetratricopeptide repeat TPR_8 PF13181.6 KIK54832.1 - 4.4e-39 129.4 34.5 0.0013 18.8 0.1 12.3 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 KIK54832.1 - 4.7e-29 98.3 24.1 0.11 12.6 0.0 12.1 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.28 KIK54832.1 - 9.6e-20 69.5 21.5 0.36 10.7 0.1 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK54832.1 - 2.4e-19 69.9 7.3 9.3e-07 28.5 0.4 4.5 1 1 4 5 5 5 5 MalT-like TPR region TPR_19 PF14559.6 KIK54832.1 - 7.7e-10 39.1 11.4 4.8 7.8 0.0 9.8 3 3 8 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK54832.1 - 1.3e-09 37.4 25.4 3.3 8.1 0.0 10.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK54832.1 - 4.2e-08 33.0 29.7 3.3 8.3 0.1 10.9 11 0 0 11 11 10 2 Tetratricopeptide repeat NSP2-B_epitope PF14757.6 KIK54832.1 - 5.1e-06 26.4 9.2 5.2 6.7 0.0 7.3 2 2 7 9 9 9 1 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF1897 PF09005.10 KIK54832.1 - 0.00019 20.8 0.1 43 3.7 0.0 6.5 9 0 0 9 9 9 0 Domain of unknown function (DUF1897) NB-ARC PF00931.22 KIK54832.1 - 0.00027 20.2 0.0 0.00083 18.6 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain Urb2 PF10441.9 KIK54832.1 - 0.00038 20.5 6.8 1.3 8.9 0.1 5.2 1 1 3 5 5 5 1 Urb2/Npa2 family DUF493 PF04359.14 KIK54832.1 - 0.0019 18.7 0.0 13 6.5 0.0 6.1 2 2 4 7 7 7 0 Protein of unknown function (DUF493) MBF1 PF08523.10 KIK54832.1 - 0.016 15.7 0.0 39 4.8 0.0 5.1 5 1 1 6 6 5 0 Multiprotein bridging factor 1 TPR_5 PF12688.7 KIK54832.1 - 0.16 12.2 14.4 42 4.4 0.1 7.0 2 2 3 7 7 7 0 Tetratrico peptide repeat DUF3856 PF12968.7 KIK54832.1 - 0.31 11.1 15.3 1.4 9.0 0.1 7.1 5 2 4 9 9 8 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 KIK54832.1 - 0.51 11.3 16.3 1.1e+02 4.0 0.0 8.9 11 0 0 11 11 9 0 Tetratricopeptide repeat AAA_19 PF13245.6 KIK54832.1 - 0.61 10.4 0.0 0.61 10.4 0.0 4.4 3 1 0 3 3 3 0 AAA domain CorA PF01544.18 KIK54832.1 - 3.2 7.0 6.0 3.7 6.8 0.2 3.5 3 2 2 5 5 5 0 CorA-like Mg2+ transporter protein TPR_3 PF07720.12 KIK54832.1 - 4.7 7.3 11.3 1.7e+02 2.4 0.0 6.9 10 0 0 10 10 8 0 Tetratricopeptide repeat O-FucT PF10250.9 KIK54833.1 - 0.00026 20.8 0.0 0.0051 16.6 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SPX PF03105.19 KIK54833.1 - 8.4 6.2 12.2 0.66 9.8 7.1 1.6 2 0 0 2 2 2 0 SPX domain U3_snoRNA_assoc PF08297.11 KIK54835.1 - 0.0089 16.7 2.7 0.0089 16.7 2.7 4.0 2 2 2 4 4 4 1 U3 snoRNA associated Nop14 PF04147.12 KIK54835.1 - 0.78 7.9 37.5 1 7.5 37.5 1.2 1 0 0 1 1 1 0 Nop14-like family Herpes_LMP1 PF05297.11 KIK54835.1 - 2.7 7.1 9.1 3.7 6.6 9.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sgf11_N PF18519.1 KIK54836.1 - 0.14 11.8 5.2 0.37 10.4 5.2 1.8 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain HTH_36 PF13730.6 KIK54837.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Stevor PF17410.2 KIK54838.1 - 0.00041 20.0 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame LapA_dom PF06305.11 KIK54838.1 - 0.0029 17.4 0.3 0.0029 17.4 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Herpes_gE PF02480.16 KIK54838.1 - 0.009 14.8 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Gemini_mov PF01708.16 KIK54838.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein Amnionless PF14828.6 KIK54838.1 - 0.021 13.7 0.0 0.023 13.6 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.9 KIK54838.1 - 0.034 12.9 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KIK54838.1 - 0.036 14.0 0.1 0.061 13.2 0.1 1.3 1 1 0 1 1 1 0 TMEM154 protein family DUF4381 PF14316.6 KIK54838.1 - 0.053 13.8 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Podoplanin PF05808.11 KIK54838.1 - 0.056 13.5 0.7 0.072 13.2 0.7 1.2 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 KIK54838.1 - 0.073 12.5 0.9 0.073 12.5 0.9 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CcmD PF04995.14 KIK54838.1 - 0.17 12.0 3.4 0.29 11.2 3.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 KIK54838.1 - 0.18 12.7 0.0 0.27 12.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KIK54838.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Plasmodium_Vir PF05795.11 KIK54838.1 - 0.26 10.7 0.0 0.32 10.4 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pneumo_att_G PF05539.11 KIK54838.1 - 0.78 9.3 3.8 0.95 9.0 3.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BRCA2 PF00634.18 KIK54840.1 - 0.048 13.4 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 BRCA2 repeat UspB PF10625.9 KIK54840.1 - 0.053 13.5 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Universal stress protein B (UspB) 4HBT PF03061.22 KIK54842.1 - 4.8e-11 42.9 0.1 7.8e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF3237 PF11578.8 KIK54846.1 - 0.00051 19.9 0.1 0.00071 19.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) rve PF00665.26 KIK54847.1 - 0.0039 17.4 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KIK54847.1 - 0.038 13.6 0.0 0.12 12.1 0.0 1.7 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF3237 PF11578.8 KIK54848.1 - 0.0046 16.8 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF3602 PF12223.8 KIK54849.1 - 0.046 14.3 8.3 0.15 12.7 2.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3602) DAO PF01266.24 KIK54850.1 - 2.1e-33 116.4 0.0 4.5e-33 115.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK54850.1 - 0.0038 17.4 0.1 0.0099 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KIK54850.1 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 KIK54850.1 - 0.059 12.6 0.0 1.3 8.2 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK54850.1 - 0.068 12.4 0.2 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 KIK54850.1 - 0.11 11.6 0.0 0.93 8.6 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KIK54850.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TAL_FSA PF00923.19 KIK54854.1 - 1.2e-93 313.6 0.1 1.4e-93 313.4 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase TAL_FSA PF00923.19 KIK54855.1 - 1.3e-91 306.9 0.0 1.5e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase TRI5 PF06330.11 KIK54856.1 - 1.1e-19 70.6 0.0 1.2e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Halogen_Hydrol PF10112.9 KIK54856.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF21 PF01595.20 KIK54859.1 - 1.5e-33 115.9 0.0 2.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIK54859.1 - 0.0003 21.2 0.1 0.78 10.2 0.0 3.3 3 0 0 3 3 3 2 CBS domain TRI5 PF06330.11 KIK54861.1 - 6.8e-21 74.5 0.0 8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Pkinase PF00069.25 KIK54864.1 - 3.4e-62 210.2 0.0 4.2e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK54864.1 - 1.5e-27 96.5 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK54864.1 - 5.7e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIK54864.1 - 0.005 15.8 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK54864.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK54864.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK54864.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4781 PF16013.5 KIK54865.1 - 0.43 9.3 4.8 0.095 11.5 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) p450 PF00067.22 KIK54867.1 - 1.2e-73 248.5 0.0 2.8e-73 247.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KIK54868.1 - 1.4e-63 214.8 0.0 5.9e-33 114.4 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KIK54868.1 - 4.8e-45 154.1 1.3 1.4e-44 152.6 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KIK54868.1 - 2.2e-33 115.6 0.0 3.2e-16 59.4 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KIK54868.1 - 5.1e-16 59.0 0.0 2.2e-15 56.9 0.0 2.2 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 KIK54868.1 - 9.7e-13 48.1 0.0 9.7e-13 48.1 0.0 2.5 3 0 0 3 3 2 1 Histidyl-tRNA synthetase APH PF01636.23 KIK54868.1 - 0.00011 22.2 0.1 0.00011 22.2 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK54868.1 - 0.017 14.8 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KIK54868.1 - 0.03 13.1 0.0 0.065 12.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIK54868.1 - 0.03 13.6 0.0 0.083 12.2 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KIK54868.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain HD PF01966.22 KIK54868.1 - 0.11 12.8 0.1 0.33 11.2 0.1 1.9 1 0 0 1 1 1 0 HD domain Glyco_hydro_127 PF07944.12 KIK54869.1 - 8e-21 74.1 1.6 2.5e-19 69.2 0.5 2.4 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Rer1 PF03248.13 KIK54870.1 - 0.0048 16.7 1.1 0.0089 15.8 0.8 1.5 1 1 0 1 1 1 1 Rer1 family DUF1793 PF08760.11 KIK54871.1 - 1.2e-12 48.6 0.1 1.2e-12 48.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 KIK54872.1 - 1.5e-59 201.6 1.4 2e-59 201.1 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KIK54872.1 - 0.00016 21.1 0.1 0.00041 19.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) F-box-like PF12937.7 KIK54874.1 - 2.3e-07 30.6 0.3 5.4e-07 29.4 0.3 1.7 1 1 0 1 1 1 1 F-box-like CpXC PF14353.6 KIK54874.1 - 0.038 14.0 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 CpXC protein F-box PF00646.33 KIK54874.1 - 0.075 12.9 0.6 6.4 6.8 0.4 2.4 2 0 0 2 2 2 0 F-box domain Imm43 PF15570.6 KIK54875.1 - 0.0078 16.2 0.2 0.9 9.6 0.0 2.2 2 0 0 2 2 2 2 Immunity protein 43 PIN PF01850.21 KIK54875.1 - 0.029 14.9 0.0 0.047 14.2 0.0 1.2 1 0 0 1 1 1 0 PIN domain ATG13 PF10033.9 KIK54878.1 - 8.7e-07 28.9 0.0 9.1e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 13 HMG_box PF00505.19 KIK54880.1 - 5.6e-10 39.5 4.7 1.8e-09 37.9 4.7 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK54880.1 - 1.2e-08 35.4 2.8 3.5e-08 33.9 2.8 1.7 1 0 0 1 1 1 1 HMG-box domain MFS_1 PF07690.16 KIK54883.1 - 5.7e-32 111.0 53.8 3.2e-31 108.5 52.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK54883.1 - 1.3e-16 60.2 16.5 1.8e-16 59.7 15.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cas_CXXC_CXXC PF09706.10 KIK54883.1 - 0.1 12.9 0.0 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Cytochrom_B_C PF00032.17 KIK54883.1 - 2.1 8.7 9.1 1.2 9.5 1.6 3.4 2 1 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD DUF3759 PF12585.8 KIK54884.1 - 4.7e-32 109.9 5.2 5.8e-32 109.6 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) TetR_C_31 PF17940.1 KIK54884.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GATase_6 PF13522.6 KIK54885.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.5 1 1 0 1 1 1 0 Glutamine amidotransferase domain GATase_4 PF13230.6 KIK54885.1 - 0.019 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II GATase_6 PF13522.6 KIK54886.1 - 4.5e-06 26.9 0.0 1.7e-05 25.0 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIK54886.1 - 0.0019 17.1 0.1 0.052 12.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II ABC2_membrane_3 PF12698.7 KIK54887.1 - 0.43 9.6 7.4 0.54 9.3 7.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-RVT PF13966.6 KIK54890.1 - 0.038 14.7 0.6 0.077 13.7 0.6 1.7 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DUF2183 PF09949.9 KIK54891.1 - 6.6e-25 87.3 0.0 1.6e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) polyprenyl_synt PF00348.17 KIK54892.1 - 2e-62 210.6 0.0 2.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase F-box-like PF12937.7 KIK54893.1 - 9e-11 41.5 0.1 1.5e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK54893.1 - 0.035 14.0 2.2 6.8 6.7 0.0 2.5 2 1 0 2 2 2 0 F-box domain LRR_2 PF07723.13 KIK54894.1 - 0.63 10.8 0.1 0.63 10.8 0.1 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat AMP-binding PF00501.28 KIK54895.1 - 3.3e-61 207.1 0.0 4.3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK54895.1 - 6.3e-55 186.1 0.0 1e-54 185.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KIK54895.1 - 2.5e-12 46.9 0.0 6.7e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIK54895.1 - 5.4e-08 33.7 0.0 1.3e-07 32.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KIK54895.1 - 0.00079 19.0 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK54895.1 - 0.0052 15.8 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EF-hand_5 PF13202.6 KIK54895.1 - 0.077 12.5 0.3 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KIK54895.1 - 0.12 12.4 0.0 0.47 10.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain F-box-like PF12937.7 KIK54896.1 - 4.5e-10 39.3 1.0 7e-10 38.6 1.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK54896.1 - 0.00089 19.1 3.0 0.0074 16.1 3.0 2.2 1 1 0 1 1 1 1 F-box domain DUF5082 PF16888.5 KIK54896.1 - 0.0066 16.7 0.2 0.0088 16.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) F-box-like PF12937.7 KIK54897.1 - 1.6e-08 34.3 0.1 5e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF2242 PF10001.9 KIK54897.1 - 0.022 14.9 0.1 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2242) NPL PF17800.1 KIK54897.1 - 0.12 12.9 0.0 0.94 10.1 0.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin-like domain AMP-binding PF00501.28 KIK54898.1 - 5.4e-16 58.2 0.0 6.5e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_17 PF00332.18 KIK54900.1 - 6e-12 45.8 8.3 7.4e-12 45.5 2.4 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 DUF3040 PF11239.8 KIK54900.1 - 0.034 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1686 PF07937.11 KIK54900.1 - 0.066 13.1 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) GRA6 PF05084.13 KIK54900.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TPPK_C PF12555.8 KIK54900.1 - 0.13 12.3 1.5 0.28 11.3 1.5 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal BatA PF07584.11 KIK54900.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Vpu PF00558.19 KIK54900.1 - 0.74 9.6 2.3 11 5.9 0.5 2.4 2 0 0 2 2 2 0 Vpu protein DNA_pol_A_exo1 PF01612.20 KIK54902.1 - 3.3e-09 36.7 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease EIIA-man PF03610.16 KIK54903.1 - 0.09 13.0 0.2 0.095 12.9 0.2 1.2 1 0 0 1 1 1 0 PTS system fructose IIA component Abhydrolase_3 PF07859.13 KIK54905.1 - 7.4e-61 205.7 0.0 9.3e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK54905.1 - 8.5e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK54905.1 - 5.3e-06 25.6 0.2 1.5e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK54905.1 - 0.00059 19.4 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KIK54905.1 - 0.088 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ntox27 PF15531.6 KIK54905.1 - 0.11 12.4 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 27 Esterase_phd PF10503.9 KIK54905.1 - 0.12 11.9 0.4 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase SHNi-TPR PF10516.9 KIK54905.1 - 0.19 11.2 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 SHNi-TPR NAD_binding_4 PF07993.12 KIK54910.1 - 3.8e-48 163.9 0.0 5.5e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK54910.1 - 3.2e-40 138.0 0.0 4.5e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIK54910.1 - 4.2e-11 43.0 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIK54910.1 - 7.7e-06 26.8 0.0 2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KIK54910.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK54910.1 - 3e-05 23.6 0.0 7.9e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK54910.1 - 0.0083 15.2 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EF-hand_5 PF13202.6 KIK54910.1 - 0.04 13.4 0.0 0.69 9.5 0.0 2.6 2 0 0 2 2 2 0 EF hand dsrm PF00035.26 KIK54911.1 - 4.9e-09 36.8 0.0 5.9e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif WW PF00397.26 KIK54911.1 - 0.098 12.8 2.1 0.23 11.6 2.1 1.7 1 0 0 1 1 1 0 WW domain Abhydrolase_3 PF07859.13 KIK54912.1 - 1.3e-21 77.4 0.0 1.7e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Transposase_21 PF02992.14 KIK54913.1 - 0.00017 20.9 0.0 0.00041 19.7 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 SpoVAD PF07451.11 KIK54913.1 - 0.034 12.9 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Abhydrolase_3 PF07859.13 KIK54915.1 - 5.8e-56 189.7 0.0 7e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK54915.1 - 2.3e-07 30.0 0.0 3.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK54915.1 - 1.5e-05 24.1 0.4 4.8e-05 22.4 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK54915.1 - 0.0078 15.7 0.0 0.8 9.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KIK54915.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.9 KIK54915.1 - 0.12 11.8 0.1 5.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase GMC_oxred_N PF00732.19 KIK54916.1 - 1.1e-56 192.4 0.0 1.7e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK54916.1 - 4.6e-30 105.0 0.0 1.1e-29 103.8 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK54916.1 - 0.00094 18.3 0.2 0.0014 17.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK54916.1 - 0.016 14.4 0.1 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK54916.1 - 0.043 13.0 0.2 0.37 10.0 0.0 2.4 3 0 0 3 3 3 0 Thi4 family NAD_binding_8 PF13450.6 KIK54916.1 - 0.086 13.1 0.1 0.33 11.2 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 KIK54918.1 - 1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK54918.1 - 3.6e-07 30.3 0.0 7.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK54918.1 - 3.9e-05 23.3 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KIK54918.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HTH_Tnp_Tc5 PF03221.16 KIK54920.1 - 1.7e-05 24.7 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain ABC_membrane PF00664.23 KIK54922.1 - 1.9e-101 339.3 26.3 3.8e-54 184.2 12.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK54922.1 - 5.9e-70 234.1 0.1 2.4e-34 118.8 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KIK54922.1 - 2.2e-14 53.4 3.9 6.9e-06 25.7 0.7 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIK54922.1 - 2.6e-07 29.8 0.5 0.0019 17.1 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KIK54922.1 - 3.9e-07 29.5 0.0 0.021 14.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 KIK54922.1 - 5.8e-07 30.0 3.6 0.0029 18.0 0.1 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KIK54922.1 - 6.1e-07 29.1 0.2 0.028 14.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK54922.1 - 1.1e-06 28.7 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK54922.1 - 1.3e-06 28.7 3.6 0.011 16.0 0.1 4.0 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KIK54922.1 - 1.6e-06 28.1 0.0 0.049 13.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KIK54922.1 - 3.9e-06 26.9 0.2 0.21 11.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KIK54922.1 - 0.00025 20.3 0.0 0.093 11.9 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 KIK54922.1 - 0.00031 21.3 0.0 0.51 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIK54922.1 - 0.00063 19.4 1.4 1.5 8.3 0.2 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KIK54922.1 - 0.0017 18.8 3.1 0.9 10.0 0.6 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK54922.1 - 0.0029 17.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KIK54922.1 - 0.0033 17.2 5.0 2 8.1 0.0 4.0 3 2 0 3 3 3 2 AAA domain NB-ARC PF00931.22 KIK54922.1 - 0.0043 16.3 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 KIK54922.1 - 0.0043 17.2 2.8 3.2 8.0 0.4 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KIK54922.1 - 0.0044 16.8 0.1 0.56 9.9 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 KIK54922.1 - 0.0074 16.2 0.1 4.2 7.3 0.1 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.14 KIK54922.1 - 0.0075 16.3 0.1 3.4 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KIK54922.1 - 0.012 15.7 0.0 6.4 6.9 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KIK54922.1 - 0.016 15.4 0.0 6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK54922.1 - 0.019 14.7 0.1 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK54922.1 - 0.019 14.1 0.0 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KIK54922.1 - 0.019 15.5 0.0 9.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK54922.1 - 0.028 14.8 0.0 2.9 8.3 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Rad17 PF03215.15 KIK54922.1 - 0.052 13.5 0.0 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 KIK54922.1 - 0.061 13.4 1.0 14 5.7 0.1 3.8 5 0 0 5 5 4 0 Helicase HerA, central domain AAA_17 PF13207.6 KIK54922.1 - 0.1 13.0 1.3 24 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF2628 PF10947.8 KIK54922.1 - 0.16 12.4 3.1 0.17 12.2 0.1 2.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2628) NACHT PF05729.12 KIK54922.1 - 0.19 11.6 0.3 7 6.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain HTH_Tnp_Tc5 PF03221.16 KIK54923.1 - 2.8e-09 36.9 0.0 3.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2236 PF09995.9 KIK54926.1 - 1.5e-15 58.0 0.0 2.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) WD40 PF00400.32 KIK54929.1 - 1.3e-130 421.5 63.3 6.5e-10 39.4 0.1 15.4 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54929.1 - 1.9e-65 217.2 3.5 0.00017 21.8 0.0 14.2 1 1 13 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK54929.1 - 4.9e-27 93.3 5.7 1.5 8.9 0.0 13.4 13 0 0 13 13 13 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK54929.1 - 1.8e-14 53.5 0.2 7.6 5.4 0.0 10.9 1 1 9 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK54929.1 - 6.1e-13 49.1 0.0 0.067 13.1 0.0 5.5 2 2 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KIK54929.1 - 5.3e-09 35.3 13.7 0.051 12.3 0.1 6.9 1 1 5 6 6 6 3 Nup133 N terminal like PQQ_3 PF13570.6 KIK54929.1 - 8.3e-08 32.5 0.2 16 6.2 0.0 8.5 6 4 5 11 11 11 0 PQQ-like domain PQQ_2 PF13360.6 KIK54929.1 - 2.6e-07 30.5 2.5 0.075 12.6 0.3 4.3 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 KIK54929.1 - 8.8e-07 28.6 0.0 29 4.8 0.0 8.5 9 0 0 9 9 9 0 PQQ enzyme repeat Pyr_redox_dim PF02852.22 KIK54929.1 - 7.2e-05 23.0 0.0 13 6.1 0.0 7.1 4 3 7 11 11 11 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Cuticle_4 PF15955.5 KIK54929.1 - 0.0002 22.0 6.6 44 4.9 0.0 8.0 9 0 0 9 9 9 0 Cuticle protein Proteasome_A_N PF10584.9 KIK54929.1 - 0.00053 19.6 22.8 35 4.2 0.0 10.2 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature DUF727 PF05303.12 KIK54929.1 - 0.00097 19.2 0.4 26 5.0 0.0 6.9 7 3 4 11 11 9 0 Protein of unknown function (DUF727) Me-amine-dh_H PF06433.11 KIK54929.1 - 0.0024 16.8 0.0 4 6.2 0.0 3.8 4 1 1 5 5 5 1 Methylamine dehydrogenase heavy chain (MADH) Peptidase_S9_N PF02897.15 KIK54929.1 - 0.007 15.2 0.0 3.6 6.3 0.0 4.9 4 2 5 9 9 9 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF3931 PF13082.6 KIK54929.1 - 0.026 14.7 0.4 88 3.4 0.0 6.1 8 0 0 8 8 7 0 Protein of unknown function (DUF3931) DUF4960 PF16324.5 KIK54929.1 - 0.093 12.3 0.1 9.9 5.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4960) PepSY PF03413.19 KIK54929.1 - 2.8 8.6 3.7 4.8e+02 1.4 0.0 4.6 5 0 0 5 5 4 0 Peptidase propeptide and YPEB domain WD40_3 PF15911.5 KIK54929.1 - 2.8 8.0 4.3 18 5.5 0.0 4.6 7 0 0 7 7 5 0 WD domain, G-beta repeat 4HFCP_synth PF04476.13 KIK54933.1 - 0.17 11.6 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 4-HFC-P synthase Oxidored_FMN PF00724.20 KIK54934.1 - 1.3e-70 238.4 0.0 1.6e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIK54934.1 - 0.0029 17.3 0.1 0.0065 16.2 0.1 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) RTA1 PF04479.13 KIK54936.1 - 1.4e-61 207.8 7.7 2.1e-61 207.2 7.7 1.3 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.13 KIK54937.1 - 2.3e-63 213.6 1.2 3.4e-63 213.0 1.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Oxidored_FMN PF00724.20 KIK54938.1 - 4.1e-80 269.6 0.0 4.8e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CENP-T_C PF15511.6 KIK54939.1 - 2.8e-07 30.6 0.0 3.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK54939.1 - 4.1e-05 23.7 0.1 5.6e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK54939.1 - 9.3e-05 22.7 0.0 0.00012 22.4 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK54939.1 - 0.00063 20.0 0.1 0.0012 19.1 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK54939.1 - 0.0014 19.0 0.1 0.0018 18.7 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK54939.1 - 0.041 14.0 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MBOAT_2 PF13813.6 KIK54940.1 - 2e-13 50.4 4.1 5.3e-13 49.0 4.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peroxidase_ext PF11895.8 KIK54941.1 - 2.6e-28 97.8 4.2 3.3e-28 97.5 2.6 2.1 2 0 0 2 2 2 1 Fungal peroxidase extension region peroxidase PF00141.23 KIK54941.1 - 2.6e-24 86.2 0.0 3.5e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase WD40 PF00400.32 KIK54942.1 - 7.3e-71 232.3 31.4 1.3e-10 41.6 0.4 9.7 8 1 1 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54942.1 - 1.7e-26 92.4 0.0 0.002 18.4 0.0 7.0 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK54942.1 - 2e-10 40.3 4.0 1.9 8.5 0.0 7.7 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK54942.1 - 3.7e-08 33.9 0.0 7.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK54942.1 - 4.6e-08 33.2 0.0 8.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK54942.1 - 1.1e-07 32.3 0.0 5.3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 KIK54942.1 - 0.00015 20.8 0.1 12 4.8 0.0 5.5 3 2 2 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK54942.1 - 0.00029 19.7 0.0 1.6 7.4 0.0 3.8 1 1 3 4 4 4 1 Nup133 N terminal like PQQ PF01011.21 KIK54942.1 - 0.001 18.9 0.0 67 3.7 0.0 5.0 5 0 0 5 5 5 0 PQQ enzyme repeat AAA_7 PF12775.7 KIK54942.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytochrom_D1 PF02239.16 KIK54942.1 - 0.014 13.9 0.0 0.88 8.0 0.0 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain Torsin PF06309.11 KIK54942.1 - 0.016 15.3 0.3 0.11 12.6 0.0 2.4 3 0 0 3 3 2 0 Torsin Proteasome_A_N PF10584.9 KIK54942.1 - 0.019 14.6 11.2 47 3.8 0.0 6.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Pyr_redox_dim PF02852.22 KIK54942.1 - 0.026 14.8 0.0 9.4 6.5 0.0 4.0 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain WD40_like PF17005.5 KIK54942.1 - 0.027 13.8 0.0 5.4 6.3 0.0 3.6 4 1 0 5 5 5 0 WD40-like domain IstB_IS21 PF01695.17 KIK54942.1 - 0.033 13.9 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIK54942.1 - 0.048 13.9 0.0 0.27 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK54942.1 - 0.059 12.5 0.3 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain PIF1 PF05970.14 KIK54942.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 KIK54942.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TMEM240 PF15207.6 KIK54942.1 - 0.068 12.9 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 TMEM240 family ATPase_2 PF01637.18 KIK54942.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK54942.1 - 0.13 11.5 0.1 1.1 8.4 0.0 2.3 2 1 0 3 3 3 0 KAP family P-loop domain DDE_Tnp_4 PF13359.6 KIK54944.1 - 2e-16 60.1 0.0 2.2e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 KIK54945.1 - 4.3e-49 163.4 19.8 5.8e-11 42.8 0.3 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54945.1 - 3.5e-22 78.5 0.1 0.00072 19.8 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK54945.1 - 3.5e-09 36.4 2.9 0.64 10.0 0.0 5.1 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK54945.1 - 2.5e-06 26.7 0.0 2.3 7.1 0.0 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9_N PF02897.15 KIK54945.1 - 2.7e-06 26.5 0.0 0.058 12.2 0.0 3.8 1 1 3 4 4 4 2 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK54945.1 - 0.00021 21.1 0.0 27 4.9 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK54945.1 - 0.00044 18.9 0.1 0.19 10.2 0.0 2.3 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KIK54945.1 - 0.00055 18.8 0.0 1.9 7.2 0.0 3.6 1 1 1 2 2 2 2 Nup133 N terminal like DUF2574 PF10836.8 KIK54945.1 - 0.0024 17.7 0.0 7.5 6.5 0.0 3.5 2 1 2 4 4 4 1 Protein of unknown function (DUF2574) PQQ_3 PF13570.6 KIK54945.1 - 0.0039 17.6 0.4 12 6.5 0.1 3.8 2 1 2 4 4 4 1 PQQ-like domain Frtz PF11768.8 KIK54945.1 - 0.0043 15.4 0.0 6 5.0 0.0 3.6 4 0 0 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz Pyr_redox_dim PF02852.22 KIK54945.1 - 0.0051 17.1 0.0 1.4 9.3 0.0 3.3 1 1 3 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Proteasome_A_N PF10584.9 KIK54945.1 - 0.037 13.7 10.5 8 6.3 0.1 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40_like PF17005.5 KIK54945.1 - 0.051 12.9 0.0 41 3.4 0.0 3.4 3 1 1 4 4 4 0 WD40-like domain AAA_16 PF13191.6 KIK54946.1 - 1.8e-06 28.4 0.0 2.6e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK54946.1 - 1.2e-05 25.2 0.0 1.9e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK54946.1 - 5.4e-05 23.6 0.0 9e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KIK54946.1 - 0.0026 17.5 0.1 0.0037 17.0 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KIK54946.1 - 0.0033 16.9 0.0 0.0067 16.0 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 KIK54946.1 - 0.0097 15.2 0.0 0.0097 15.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK54946.1 - 0.011 15.9 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK54946.1 - 0.023 14.4 0.0 0.024 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK54946.1 - 0.026 14.0 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KIK54946.1 - 0.033 14.6 0.1 0.062 13.7 0.0 1.6 1 1 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KIK54946.1 - 0.046 13.4 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_18 PF13238.6 KIK54946.1 - 0.056 14.0 0.0 0.074 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK54946.1 - 0.057 12.6 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 KIK54946.1 - 0.15 11.3 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain PIF1 PF05970.14 KIK54946.1 - 0.19 10.8 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_5 PF07728.14 KIK54946.1 - 0.2 11.6 0.0 0.45 10.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) p450 PF00067.22 KIK54949.1 - 1.2e-12 47.4 0.0 2.1e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Spc7_C2 PF15577.6 KIK54949.1 - 0.068 13.3 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Spc7_C2 PRAI PF00697.22 KIK54949.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase WD40 PF00400.32 KIK54950.1 - 1.4e-127 411.8 62.8 7.7e-11 42.4 0.8 12.4 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54950.1 - 7.1e-54 180.1 4.1 0.0068 16.7 0.0 12.2 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK54950.1 - 7.5e-24 83.1 16.7 3.4 7.7 0.0 12.5 12 0 0 12 12 12 10 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK54950.1 - 2.6e-17 62.8 0.0 5.7 5.8 0.0 11.6 2 2 7 12 12 12 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK54950.1 - 5.1e-10 38.9 25.2 11 5.8 0.0 12.1 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KIK54950.1 - 5.2e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 KIK54950.1 - 3.1e-09 35.8 0.1 2.3 6.6 0.0 5.1 2 1 3 5 5 5 4 Cytochrome D1 heme domain AAA_16 PF13191.6 KIK54950.1 - 1.4e-08 35.3 0.0 2.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK54950.1 - 3e-08 33.2 0.0 74 3.5 0.0 8.9 9 0 0 9 9 9 0 PQQ enzyme repeat Nucleoporin_N PF08801.11 KIK54950.1 - 2.5e-07 29.8 0.4 1.7 7.3 0.0 6.9 1 1 5 6 6 6 1 Nup133 N terminal like AAA PF00004.29 KIK54950.1 - 1e-06 29.2 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PQQ_3 PF13570.6 KIK54950.1 - 9.9e-05 22.7 13.1 40 4.9 0.1 8.7 6 6 4 10 10 10 0 PQQ-like domain NB-ARC PF00931.22 KIK54950.1 - 0.00017 20.9 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain WD40_like PF17005.5 KIK54950.1 - 0.00048 19.5 0.0 28 3.9 0.0 6.1 4 2 1 7 7 7 0 WD40-like domain Peptidase_S9_N PF02897.15 KIK54950.1 - 0.0037 16.1 1.1 16 4.2 0.0 5.6 4 3 2 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_22 PF13401.6 KIK54950.1 - 0.005 17.1 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK54950.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KIK54950.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Torsin PF06309.11 KIK54950.1 - 0.029 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Torsin KAP_NTPase PF07693.14 KIK54950.1 - 0.046 13.0 0.0 0.45 9.7 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 KIK54950.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIK54950.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 KIK54950.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KIK54950.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KIK54950.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cuticle_4 PF15955.5 KIK54950.1 - 0.62 10.8 3.8 49 4.7 0.0 5.5 8 0 0 8 8 5 0 Cuticle protein CENP-T_C PF15511.6 KIK54951.1 - 8e-07 29.2 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK54951.1 - 0.00022 21.3 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK54951.1 - 0.00046 20.5 0.1 0.00066 20.0 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK54951.1 - 0.00049 20.3 0.1 0.00075 19.7 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK54951.1 - 0.0011 19.3 0.1 0.0013 19.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK54951.1 - 0.091 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MBOAT_2 PF13813.6 KIK54952.1 - 1e-12 48.1 3.9 1.5e-12 47.6 3.9 1.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family COX2-transmemb PF09125.10 KIK54952.1 - 1.1 9.1 4.0 0.27 11.1 0.7 1.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane VitK2_biosynth PF02621.14 KIK54953.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis DCP2 PF05026.13 KIK54954.1 - 0.052 13.9 0.6 0.14 12.5 0.2 1.9 2 0 0 2 2 2 0 Dcp2, box A domain WD40 PF00400.32 KIK54955.1 - 6.6e-93 302.1 29.0 3.1e-11 43.6 0.3 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK54955.1 - 1e-40 137.9 0.4 0.00038 20.7 0.0 8.0 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK54955.1 - 1.3e-19 69.6 7.4 1 9.3 0.0 8.5 8 0 0 8 8 8 6 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK54955.1 - 7e-15 54.8 0.0 0.21 10.5 0.0 7.8 1 1 6 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK54955.1 - 1.3e-09 38.3 0.0 0.0085 16.0 0.0 3.6 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KIK54955.1 - 1.1e-07 31.4 14.5 16 5.3 0.0 8.1 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KIK54955.1 - 5e-07 28.6 0.2 0.39 9.2 0.0 3.3 1 1 3 4 4 4 4 Cytochrome D1 heme domain Peptidase_S9_N PF02897.15 KIK54955.1 - 1.5e-05 24.0 0.1 4.2 6.0 0.0 5.3 1 1 6 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK54955.1 - 1.8e-05 24.5 0.1 50 4.1 0.0 6.3 6 0 0 6 6 6 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK54955.1 - 2.6e-05 24.5 0.4 44 4.7 0.0 5.9 5 2 2 7 7 7 0 PQQ-like domain Pyr_redox_dim PF02852.22 KIK54955.1 - 3.4e-05 24.1 0.0 29 5.0 0.0 5.7 1 1 6 7 7 7 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Frtz PF11768.8 KIK54955.1 - 0.0001 20.8 0.0 19 3.4 0.0 6.1 4 3 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4072 PF13284.6 KIK54955.1 - 0.00035 21.0 4.5 83 3.7 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF4072) WD40_like PF17005.5 KIK54955.1 - 0.00052 19.4 0.0 25 4.1 0.0 5.3 6 1 0 6 6 6 0 WD40-like domain CHASE9 PF17153.4 KIK54955.1 - 0.00071 19.7 0.2 40 4.4 0.0 5.6 7 0 0 7 7 7 0 Periplasmic sensor domain, extracellular Emaravirus_P4 PF16505.5 KIK54955.1 - 0.044 12.8 0.0 0.55 9.2 0.0 2.6 2 0 0 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily Nup160 PF11715.8 KIK54955.1 - 0.48 9.0 5.6 31 3.0 0.2 5.0 4 2 3 7 7 7 0 Nucleoporin Nup120/160 Cuticle_4 PF15955.5 KIK54955.1 - 2.9 8.7 11.1 79 4.0 0.1 6.1 8 0 0 8 8 7 0 Cuticle protein AAA_16 PF13191.6 KIK54956.1 - 6.2e-10 39.7 0.0 7.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK54956.1 - 7.3e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK54956.1 - 2.8e-06 27.8 0.0 4.9e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK54956.1 - 0.00013 22.3 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK54956.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NB-ARC PF00931.22 KIK54956.1 - 0.003 16.8 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PIF1 PF05970.14 KIK54956.1 - 0.0045 16.2 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ATPase_2 PF01637.18 KIK54956.1 - 0.0053 16.7 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KIK54956.1 - 0.0058 16.4 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KIK54956.1 - 0.0092 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein KAP_NTPase PF07693.14 KIK54956.1 - 0.011 15.0 0.0 0.76 8.9 0.0 2.0 1 1 0 2 2 2 0 KAP family P-loop domain Torsin PF06309.11 KIK54956.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.6 KIK54956.1 - 0.036 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK54956.1 - 0.041 13.6 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase DUF2075 PF09848.9 KIK54956.1 - 0.042 13.1 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 KIK54956.1 - 0.051 12.6 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KIK54956.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KIK54956.1 - 0.099 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 KIK54956.1 - 0.19 10.6 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain APS_kinase PF01583.20 KIK54956.1 - 0.2 11.5 0.0 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 KIK54956.1 - 0.23 11.0 0.0 16 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DDE_Tnp_4 PF13359.6 KIK54959.1 - 3.3e-14 52.8 0.0 4.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PH_16 PF17838.1 KIK54961.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 PH domain Cobl PF09469.10 KIK54963.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Cauli_VI PF01693.16 KIK54964.1 - 1.1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin SBF2 PF12335.8 KIK54966.1 - 0.073 12.7 2.0 0.086 12.4 2.0 1.0 1 0 0 1 1 1 0 Myotubularin protein p450 PF00067.22 KIK54968.1 - 7.8e-56 189.7 0.0 9.7e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cation_efflux PF01545.21 KIK54969.1 - 8.1e-18 64.9 9.3 1.1e-17 64.5 9.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK54969.1 - 4.5e-08 33.1 0.5 2.6e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 Dimerisation domain of Zinc Transporter GET2 PF08690.10 KIK54969.1 - 0.58 9.8 2.7 1.2 8.7 2.7 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4212 PF13937.6 KIK54969.1 - 9 6.8 8.4 1.1 9.6 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Retrotran_gag_3 PF14244.6 KIK54971.1 - 0.058 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type p450 PF00067.22 KIK54972.1 - 5.9e-46 157.2 0.0 7.5e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54973.1 - 6.2e-54 183.5 0.0 8.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ion_trans_2 PF07885.16 KIK54974.1 - 1.6e-28 98.4 38.4 3.8e-17 62.0 14.5 3.1 3 0 0 3 3 3 2 Ion channel Shisa PF13908.6 KIK54974.1 - 0.05 13.9 0.1 2.4 8.4 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF1635 PF07795.11 KIK54974.1 - 0.35 10.7 2.2 0.77 9.6 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF2207 PF09972.9 KIK54974.1 - 2.5 6.8 8.4 0.23 10.2 0.3 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) p450 PF00067.22 KIK54975.1 - 5.6e-50 170.4 0.0 7.5e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54976.1 - 3.5e-56 190.9 0.0 4.7e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK54978.1 - 3.4e-56 190.9 0.0 4.6e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 KIK54979.1 - 2.3e-29 102.7 0.0 4.7e-29 101.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KIK54979.1 - 1.8 9.1 3.8 5.3 7.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3471) zf-C2H2 PF00096.26 KIK54980.1 - 8.1e-11 41.8 11.7 3.2e-05 24.1 1.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK54980.1 - 1.4e-07 31.7 9.5 0.0012 19.5 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK54980.1 - 1.2e-05 25.5 10.4 0.0032 17.8 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 KIK54980.1 - 0.017 15.1 2.2 0.017 15.1 2.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 KIK54980.1 - 0.02 14.9 0.9 0.02 14.9 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK54980.1 - 0.081 13.2 3.5 0.26 11.6 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIK54980.1 - 0.42 10.6 5.7 1.3 9.0 1.6 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 KIK54980.1 - 0.5 10.8 4.0 1.2 9.6 0.5 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type AAA_12 PF13087.6 KIK54982.1 - 9.3e-43 146.2 0.0 1.7e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK54982.1 - 7.5e-26 91.5 0.0 7.2e-14 52.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK54982.1 - 2.7e-13 50.1 0.0 5.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK54982.1 - 3.9e-12 46.7 0.0 9.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIK54982.1 - 0.00029 20.5 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KIK54982.1 - 0.00044 20.1 0.0 4 7.1 0.0 3.3 2 1 1 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KIK54982.1 - 0.0015 18.8 0.0 0.0054 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK54982.1 - 0.002 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2HC_2 PF13913.6 KIK54982.1 - 0.0051 16.7 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type UvrD_C_2 PF13538.6 KIK54982.1 - 0.0098 15.7 0.4 0.052 13.4 0.4 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KIK54982.1 - 0.012 15.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 KIK54982.1 - 0.013 15.9 0.0 0.048 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain Helicase_RecD PF05127.14 KIK54982.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.14 KIK54982.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-C2H2_4 PF13894.6 KIK54982.1 - 0.049 14.5 0.4 0.14 13.1 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger AAA PF00004.29 KIK54982.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF5641 PF18701.1 KIK54982.1 - 0.16 12.2 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5641) DUF2075 PF09848.9 KIK54982.1 - 0.19 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F-box-like PF12937.7 KIK54983.1 - 3.9e-07 29.8 0.0 7.6e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK54983.1 - 0.00013 21.7 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 F-box domain FTA4 PF13093.6 KIK54983.1 - 0.068 13.1 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 UQ_con PF00179.26 KIK54985.1 - 3.7e-26 91.5 0.0 6.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 KIK54985.1 - 8e-11 42.5 0.1 9.6e-08 32.6 0.0 3.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KIK54985.1 - 6.4e-09 36.3 0.0 5.8e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4148 PF13663.6 KIK54985.1 - 0.042 14.0 0.3 0.12 12.5 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) RWD PF05773.22 KIK54985.1 - 0.098 12.9 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 RWD domain UN_NPL4 PF11543.8 KIK54985.1 - 0.13 12.8 0.0 5.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KIK54985.1 - 0.57 10.0 3.6 0.52 10.1 0.1 2.2 2 0 0 2 2 2 0 Coilin N-terminus zf_CCCH_4 PF18345.1 KIK54985.1 - 0.7 10.0 2.3 2.1 8.5 2.3 1.9 1 0 0 1 1 1 0 Zinc finger domain zf-ANAPC11 PF12861.7 KIK54985.1 - 2.9 8.0 9.2 0.28 11.3 4.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK54985.1 - 3.1 8.2 17.7 0.062 13.6 6.3 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain Retrotran_gag_2 PF14223.6 KIK54986.1 - 2.3e-14 53.3 0.3 3e-14 52.8 0.3 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_Tnp_Tc5 PF03221.16 KIK54987.1 - 0.086 12.9 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain TPR_2 PF07719.17 KIK54987.1 - 0.17 12.1 0.5 0.49 10.6 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 KIK54988.1 - 1.6e-06 27.8 0.1 2.7e-06 27.0 0.0 1.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region GET2 PF08690.10 KIK54989.1 - 1.1 8.9 5.3 1.7 8.2 5.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 WW PF00397.26 KIK54992.1 - 1.6e-05 24.9 2.8 3.4e-05 23.8 2.8 1.6 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 KIK54992.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain p450 PF00067.22 KIK54994.1 - 2.6e-52 178.1 0.0 3.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_fungal PF17667.1 KIK54996.1 - 0.031 13.0 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_fungal PF17667.1 KIK54997.1 - 3.7e-43 147.9 0.0 6.2e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK54997.1 - 0.00032 20.1 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.22 KIK54998.1 - 1.8e-54 185.3 0.0 2.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 KIK54999.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KIK55000.1 - 5.5e-50 170.3 51.6 1.6e-47 162.1 53.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK55000.1 - 8.6e-11 41.3 11.7 8.6e-11 41.3 11.7 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK55001.1 - 2.5e-50 171.4 53.6 7e-48 163.3 55.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK55001.1 - 1.1e-13 50.5 39.6 3.1e-13 49.0 39.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK55001.1 - 4e-11 42.5 12.9 4e-11 42.5 12.9 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.22 KIK55002.1 - 1.2e-46 159.4 0.0 1.7e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GspL_C PF12693.7 KIK55002.1 - 0.13 12.1 0.0 18 5.1 0.0 2.5 3 0 0 3 3 3 0 GspL periplasmic domain UNC-50 PF05216.13 KIK55005.1 - 1e-85 286.8 14.1 1.1e-85 286.7 14.1 1.0 1 0 0 1 1 1 1 UNC-50 family adh_short PF00106.25 KIK55006.1 - 5e-34 117.5 0.0 6.4e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK55006.1 - 4.8e-27 95.0 0.0 6.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK55006.1 - 2.6e-06 27.5 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK55006.1 - 0.031 13.7 0.2 0.15 11.5 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK55006.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain IL13 PF03487.13 KIK55008.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin-13 His_Phos_2 PF00328.22 KIK55009.1 - 1.3e-27 97.1 0.0 1.8e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hamartin PF04388.12 KIK55010.1 - 6.2 5.4 15.3 7.3 5.1 15.3 1.1 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.7 KIK55011.1 - 4.4e-05 23.3 1.3 7e-05 22.6 0.2 1.9 2 1 1 3 3 3 1 F-box-like F-box_5 PF18511.1 KIK55011.1 - 0.016 14.7 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box NIF PF03031.18 KIK55014.1 - 1.1e-19 70.7 0.0 4.9e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TPR_12 PF13424.6 KIK55015.1 - 1.6e-54 182.1 25.8 1.6e-08 34.7 0.1 11.2 3 3 9 13 13 13 13 Tetratricopeptide repeat SNAP PF14938.6 KIK55015.1 - 3.4e-29 102.2 11.1 4.1e-07 29.7 0.4 5.7 1 1 4 5 5 5 5 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.9 KIK55015.1 - 1.2e-19 69.5 5.6 0.032 13.7 0.0 12.7 14 0 0 14 14 14 3 SHNi-TPR TPR_MalT PF17874.1 KIK55015.1 - 3.3e-19 69.4 20.6 3.3e-05 23.4 0.9 4.9 1 1 5 6 6 6 6 MalT-like TPR region TPR_2 PF07719.17 KIK55015.1 - 1.1e-12 47.0 28.4 0.059 13.5 0.1 12.9 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIK55015.1 - 1.3e-12 47.1 28.9 0.045 13.6 0.1 12.1 14 0 0 14 14 13 3 Tetratricopeptide repeat NTS PF15447.6 KIK55015.1 - 7.3e-11 42.4 3.5 7.8 7.1 0.1 10.3 11 0 0 11 11 10 0 N-terminal segments of PfEMP1 UPF0147 PF03685.13 KIK55015.1 - 8.5e-10 38.6 0.0 2.7 8.1 0.0 8.3 7 3 2 9 9 8 2 Uncharacterised protein family (UPF0147) Antimicrobial17 PF08129.11 KIK55015.1 - 1.2e-09 38.0 0.0 12 6.0 0.0 9.4 11 1 1 12 12 10 0 Alpha/beta enterocin family TPR_1 PF00515.28 KIK55015.1 - 2e-07 30.5 17.3 0.59 10.0 0.3 9.9 10 0 0 10 10 10 1 Tetratricopeptide repeat RPN7 PF10602.9 KIK55015.1 - 2e-05 24.4 7.9 0.061 13.0 0.2 5.2 3 2 2 6 6 6 3 26S proteasome subunit RPN7 Nore1-SARAH PF16517.5 KIK55015.1 - 9.3e-05 22.3 4.7 17 5.4 0.0 7.7 9 0 0 9 9 9 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF1547 PF07577.11 KIK55015.1 - 0.00012 22.4 0.3 19 5.7 0.0 6.3 4 2 4 8 8 6 0 Domain of Unknown Function (DUF1547) CRC_subunit PF08624.10 KIK55015.1 - 0.00028 21.3 1.4 1.1e+02 3.2 0.0 8.0 5 4 6 12 12 11 0 Chromatin remodelling complex Rsc7/Swp82 subunit AbiEi_3_N PF17194.4 KIK55015.1 - 0.00054 19.9 2.1 37 4.4 0.0 6.4 5 2 3 8 8 8 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain CK2S PF15011.6 KIK55015.1 - 0.00078 19.4 15.1 15 5.5 0.0 7.5 2 2 7 10 10 10 0 Casein Kinase 2 substrate SmaI PF17411.2 KIK55015.1 - 0.002 17.3 0.3 15 4.7 0.0 4.8 4 1 2 6 6 6 0 Type II site-specific deoxyribonuclease HsbA PF12296.8 KIK55015.1 - 0.0025 18.3 0.4 1.2e+02 3.1 0.0 5.8 5 2 1 7 7 6 0 Hydrophobic surface binding protein A Tox-REase-5 PF15648.6 KIK55015.1 - 0.0061 17.0 3.4 64 4.1 0.0 6.9 10 0 0 10 10 7 0 Restriction endonuclease fold toxin 5 TPR_11 PF13414.6 KIK55015.1 - 0.035 13.8 1.9 22 4.8 0.3 5.3 8 0 0 8 8 6 0 TPR repeat Peptidase_M54 PF07998.11 KIK55015.1 - 0.052 13.5 0.6 18 5.3 0.0 3.7 2 2 2 4 4 4 0 Peptidase family M54 HycH PF07450.11 KIK55015.1 - 0.18 12.2 3.6 54 4.2 0.1 5.1 4 2 1 6 6 5 0 Formate hydrogenlyase maturation protein HycH DUF1289 PF06945.13 KIK55015.1 - 0.51 10.2 2.6 5.8 6.8 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1289) ANAPC3 PF12895.7 KIK55015.1 - 0.85 9.9 20.2 22 5.4 0.3 8.8 2 2 6 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF724 PF05266.14 KIK55015.1 - 1.7 8.5 4.8 79 3.0 0.1 4.3 5 0 0 5 5 4 0 Protein of unknown function (DUF724) PE PF00934.20 KIK55015.1 - 1.9 8.8 7.0 42 4.6 0.1 5.8 8 0 0 8 8 4 0 PE family TPR_16 PF13432.6 KIK55015.1 - 2.3 8.9 6.2 41 4.9 0.0 5.5 8 1 0 8 8 4 0 Tetratricopeptide repeat OEP PF02321.18 KIK55015.1 - 2.5 7.9 11.2 6.1 6.6 0.7 4.5 4 1 0 4 4 4 0 Outer membrane efflux protein NB-ARC PF00931.22 KIK55016.1 - 4.4e-08 32.6 0.0 5.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KIK55016.1 - 2.5e-07 30.7 0.1 3.7e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK55016.1 - 3.5e-06 27.5 0.1 0.00013 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KIK55016.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KIK55016.1 - 0.0045 17.3 0.1 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KIK55016.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KIK55016.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KIK55016.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 KIK55016.1 - 0.18 11.5 0.5 1.8 8.2 0.5 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein Pinin_SDK_N PF04697.13 KIK55017.1 - 0.077 13.6 1.6 0.19 12.4 1.6 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region MFS_1 PF07690.16 KIK55018.1 - 3.5e-22 78.8 56.8 2.1e-19 69.7 47.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK55019.1 - 2.7e-28 98.9 68.2 8.3e-21 74.3 41.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 KIK55020.1 - 0.00018 21.5 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_10 PF13374.6 KIK55021.1 - 3.3e-90 293.8 10.7 2.9e-10 39.7 0.0 9.0 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK55021.1 - 6.7e-68 225.0 26.5 2.9e-14 53.1 0.2 6.2 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK55021.1 - 7.2e-27 94.6 16.3 3.7e-13 49.6 2.8 2.9 1 1 2 3 3 3 3 MalT-like TPR region TPR_17 PF13431.6 KIK55021.1 - 2.7e-17 61.8 3.6 0.7 10.4 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK55021.1 - 7.6e-16 56.9 14.8 0.071 13.2 0.0 8.6 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK55021.1 - 1.1e-13 50.1 15.2 0.35 11.1 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55021.1 - 6.1e-13 48.0 13.5 0.14 12.0 0.0 8.3 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 KIK55021.1 - 4.1e-11 42.4 0.0 0.56 11.0 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK55021.1 - 8e-10 38.1 19.0 0.023 14.9 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK55021.1 - 2.1e-08 34.7 0.6 0.1 13.3 0.2 6.5 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK55021.1 - 4.6e-08 33.5 6.4 0.76 10.3 0.0 6.2 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK55021.1 - 2.1e-05 25.0 10.1 1.8 9.6 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat DUF1897 PF09005.10 KIK55021.1 - 9.5e-05 21.8 5.2 8.3 6.0 0.0 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1897) RPN7 PF10602.9 KIK55021.1 - 0.0002 21.1 9.2 0.036 13.8 0.2 4.9 2 2 4 6 6 6 1 26S proteasome subunit RPN7 PPR PF01535.20 KIK55021.1 - 0.00083 19.5 8.1 12 6.4 0.0 6.4 7 0 0 7 7 7 0 PPR repeat DUF4074 PF13293.6 KIK55021.1 - 0.0017 18.6 0.3 44 4.5 0.0 6.1 8 0 0 8 8 8 0 Domain of unknown function (DUF4074) DUF4919 PF16266.5 KIK55021.1 - 0.0036 17.3 2.3 14 5.6 0.0 4.8 1 1 4 6 6 6 0 Domain of unknown function (DUF4919) DHDPS PF00701.22 KIK55021.1 - 0.016 13.9 2.9 5.1 5.7 0.0 5.0 1 1 7 8 8 8 0 Dihydrodipicolinate synthetase family Cytochrom_B562 PF07361.11 KIK55021.1 - 0.071 13.8 11.2 28 5.4 1.0 5.9 4 2 1 5 5 5 0 Cytochrome b562 ABC_tran PF00005.27 KIK55022.1 - 2.5e-41 141.4 0.3 1.4e-24 87.2 0.1 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK55022.1 - 4e-22 79.2 13.9 7.2e-22 78.3 13.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KIK55022.1 - 9.3e-12 44.9 3.5 0.0075 15.7 0.1 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIK55022.1 - 7e-07 29.0 0.0 0.056 13.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIK55022.1 - 2.7e-06 27.9 0.2 0.087 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KIK55022.1 - 4.1e-06 26.0 0.0 0.0043 16.1 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KIK55022.1 - 1.6e-05 24.5 0.7 0.055 13.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK55022.1 - 2.6e-05 24.8 0.2 0.0056 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK55022.1 - 2.7e-05 24.4 0.1 0.58 10.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KIK55022.1 - 0.0011 18.8 7.3 0.098 12.4 0.6 3.9 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KIK55022.1 - 0.0017 18.5 1.6 0.022 14.8 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KIK55022.1 - 0.0024 17.7 0.1 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 KIK55022.1 - 0.0028 17.2 0.1 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 KIK55022.1 - 0.0035 17.1 0.2 3.9 7.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIK55022.1 - 0.0044 17.1 0.6 0.47 10.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK55022.1 - 0.0053 16.7 0.1 3.6 7.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DEAD PF00270.29 KIK55022.1 - 0.0074 16.1 0.4 2.1 8.1 0.2 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KIK55022.1 - 0.0075 16.8 0.0 2.4 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 KIK55022.1 - 0.0076 15.1 0.1 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein Pox_A32 PF04665.12 KIK55022.1 - 0.0088 15.5 0.7 2.1 7.7 0.1 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Dynamin_N PF00350.23 KIK55022.1 - 0.011 15.8 0.5 4.6 7.3 0.2 2.4 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 KIK55022.1 - 0.023 14.6 0.2 0.75 9.7 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIK55022.1 - 0.025 15.0 0.4 1.5 9.2 0.0 3.3 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KIK55022.1 - 0.026 14.1 1.7 0.34 10.5 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIK55022.1 - 0.047 13.6 0.2 9.1 6.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.9 KIK55022.1 - 0.05 12.8 0.3 2 7.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KIK55022.1 - 0.057 12.8 0.0 9.5 5.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KIK55022.1 - 0.061 13.0 0.9 11 5.7 0.4 2.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK55022.1 - 0.077 13.0 0.1 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KIK55022.1 - 0.084 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK55022.1 - 0.096 12.6 0.6 24 4.8 0.0 2.9 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 KIK55022.1 - 0.11 11.8 0.0 6.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KIK55022.1 - 0.12 11.3 0.5 8.4 5.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TPR_10 PF13374.6 KIK55025.1 - 1.7e-88 288.4 22.4 2.8e-10 39.7 0.1 10.0 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 KIK55025.1 - 5.3e-85 279.8 40.4 8.6e-15 54.8 0.3 7.5 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK55025.1 - 1.4e-27 96.9 16.9 1.3e-11 44.5 2.3 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 KIK55025.1 - 1e-21 75.3 23.9 0.0027 17.6 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK55025.1 - 5.1e-21 73.0 27.4 0.098 12.8 0.1 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 KIK55025.1 - 5.3e-18 64.0 14.2 0.011 16.0 0.2 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55025.1 - 8.7e-17 60.2 24.9 0.27 11.1 0.0 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_4 PF07721.14 KIK55025.1 - 3.6e-13 48.8 0.4 1 10.2 0.1 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK55025.1 - 1.5e-12 46.7 29.9 0.15 12.3 0.1 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK55025.1 - 9.2e-11 42.1 17.5 0.11 13.1 0.0 8.0 1 1 8 9 9 9 3 Tetratricopeptide repeat PPR PF01535.20 KIK55025.1 - 5.6e-09 35.7 11.5 0.98 9.8 0.0 8.5 9 0 0 9 9 9 2 PPR repeat TPR_16 PF13432.6 KIK55025.1 - 6e-09 36.4 16.1 0.15 12.7 0.2 7.9 6 2 3 9 9 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK55025.1 - 1.9e-07 31.3 22.1 2.2 9.3 0.1 8.1 8 1 1 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK55025.1 - 4e-06 26.9 9.7 0.18 12.1 0.0 4.7 1 1 5 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF1897 PF09005.10 KIK55025.1 - 0.00012 21.5 11.5 5.5 6.6 0.0 7.0 7 0 0 7 7 7 1 Domain of unknown function (DUF1897) RPN7 PF10602.9 KIK55025.1 - 0.00047 19.9 10.0 2 8.1 0.1 5.2 3 1 3 6 6 6 2 26S proteasome subunit RPN7 DHDPS PF00701.22 KIK55025.1 - 0.0012 17.6 6.9 5.3 5.7 0.0 5.8 1 1 6 7 7 7 1 Dihydrodipicolinate synthetase family DUF4074 PF13293.6 KIK55025.1 - 0.006 16.8 0.3 46 4.4 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4074) DUF4919 PF16266.5 KIK55025.1 - 0.0074 16.3 10.6 6.9 6.6 0.2 5.1 3 2 3 6 6 6 1 Domain of unknown function (DUF4919) TPR_9 PF13371.6 KIK55025.1 - 0.014 15.6 7.9 2.6 8.3 0.1 5.3 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_5 PF12688.7 KIK55025.1 - 0.05 13.9 7.1 14 6.0 0.0 4.8 3 1 3 6 6 6 0 Tetratrico peptide repeat TPR_6 PF13174.6 KIK55025.1 - 0.21 12.3 16.2 15 6.5 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN6_N PF18055.1 KIK55025.1 - 0.36 11.2 17.3 1.3 9.4 0.4 4.8 2 2 4 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain DASH_Dad4 PF08650.10 KIK55025.1 - 0.72 9.9 4.3 17 5.5 0.1 4.5 5 0 0 5 5 5 0 DASH complex subunit Dad4 TPR_3 PF07720.12 KIK55025.1 - 1.2 9.2 13.2 10 6.2 0.4 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_2 PF13041.6 KIK55025.1 - 2.4 8.4 7.5 57 4.0 0.1 5.2 6 0 0 6 6 5 0 PPR repeat family Thaumatin PF00314.17 KIK55026.1 - 5.4e-10 39.3 4.0 3.6e-06 26.8 1.6 2.7 1 1 2 3 3 3 2 Thaumatin family Metallophos PF00149.28 KIK55028.1 - 1.7e-36 126.6 0.1 3.3e-36 125.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KIK55028.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) MFS_1 PF07690.16 KIK55030.1 - 1.3e-35 123.0 27.0 1.3e-35 123.0 27.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK55030.1 - 2.5e-11 43.1 7.8 2.5e-11 43.1 7.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIK55030.1 - 0.0068 14.9 3.5 0.01 14.3 3.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 KIK55030.1 - 8.4 6.3 7.0 2 8.3 0.1 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Mg_trans_NIPA PF05653.14 KIK55031.1 - 3.3e-98 328.4 15.8 3.9e-98 328.2 15.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIK55031.1 - 0.005 17.0 5.8 0.005 17.0 5.8 3.1 3 0 0 3 3 3 1 EamA-like transporter family DUF2530 PF10745.9 KIK55031.1 - 0.59 10.4 3.4 0.59 10.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) G-alpha PF00503.20 KIK55033.1 - 6.6e-127 423.5 0.0 1.1e-126 422.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK55033.1 - 2.3e-06 27.2 0.2 5.5e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family ADH_N PF08240.12 KIK55034.1 - 5.3e-22 77.8 0.4 9.1e-22 77.0 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK55034.1 - 1.6e-17 63.7 0.1 6.3e-17 61.8 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK55034.1 - 5.5e-07 29.3 1.1 0.034 13.6 0.0 3.3 3 1 0 3 3 3 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KIK55034.1 - 0.0029 16.9 0.1 0.0049 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KIK55034.1 - 0.0035 18.4 0.1 0.026 15.6 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KIK55034.1 - 0.0041 17.8 0.1 0.93 10.2 0.2 2.5 1 1 1 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KIK55034.1 - 0.064 12.8 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 KIK55034.1 - 0.084 13.5 0.1 1.4 9.6 0.1 2.6 2 1 0 2 2 2 0 Methyltransferase domain DUF1853 PF08907.11 KIK55034.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) adh_short_C2 PF13561.6 KIK55035.1 - 8.2e-52 176.1 0.0 3.4e-46 157.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK55035.1 - 4.6e-47 160.0 0.0 9.5e-38 129.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KIK55035.1 - 1.7e-07 31.4 0.0 5e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.11 KIK55035.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Eno-Rase_NADH_b PF12242.8 KIK55035.1 - 0.03 14.1 0.3 0.057 13.2 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KIK55035.1 - 0.06 12.8 0.0 0.18 11.2 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIK55035.1 - 0.14 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_transf_3 PF02515.17 KIK55036.1 - 5.3e-44 150.8 0.0 8e-40 137.1 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.16 KIK55037.1 - 5.9e-32 111.0 28.2 5.9e-32 111.0 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK55037.1 - 7e-11 41.6 8.9 7e-11 41.6 8.9 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIK55037.1 - 7e-05 21.4 3.7 0.00011 20.8 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RSN1_7TM PF02714.15 KIK55038.1 - 9.1e-80 267.9 24.1 2e-79 266.7 24.1 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIK55038.1 - 5.4e-38 130.2 3.8 5.4e-38 130.2 3.8 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIK55038.1 - 1.8e-32 113.0 0.0 1.5e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KIK55038.1 - 6.1e-14 52.0 0.1 1.6e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Alpha-amylase PF00128.24 KIK55039.1 - 2.9e-24 86.3 0.4 6.8e-24 85.0 0.4 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KIK55039.1 - 7.8e-07 29.2 0.6 2.3e-06 27.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KIK55039.1 - 8e-07 27.7 0.2 0.00097 17.5 0.1 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 UCH PF00443.29 KIK55041.1 - 0.0039 16.7 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3824 PF12868.7 KIK55041.1 - 0.0099 16.6 0.0 0.016 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) TPR_12 PF13424.6 KIK55042.1 - 7e-48 160.8 24.7 4.9e-08 33.2 0.0 9.1 4 4 7 11 11 11 11 Tetratricopeptide repeat SNAP PF14938.6 KIK55042.1 - 1.8e-20 73.5 18.0 1.8e-05 24.3 0.3 5.1 1 1 5 6 6 6 6 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KIK55042.1 - 3.7e-18 64.8 25.6 0.074 12.9 0.1 11.9 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK55042.1 - 1e-15 56.5 28.3 0.4 10.9 0.1 12.5 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK55042.1 - 4.4e-14 52.6 22.2 0.00024 20.6 0.2 4.1 2 1 2 4 4 4 4 MalT-like TPR region SHNi-TPR PF10516.9 KIK55042.1 - 3.4e-13 48.8 0.0 0.5 9.9 0.0 8.9 10 0 0 10 10 10 2 SHNi-TPR TPR_4 PF07721.14 KIK55042.1 - 3.3e-08 33.4 11.7 3.3 8.6 0.1 10.1 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK55042.1 - 2.8e-06 27.0 3.4 10 6.4 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55042.1 - 9.4e-06 25.2 17.7 7.5 6.6 0.2 9.8 11 0 0 11 11 10 1 Tetratricopeptide repeat DUF1876 PF08962.11 KIK55042.1 - 1.4e-05 24.9 2.3 3.3 7.7 0.0 7.4 8 0 0 8 8 8 1 Domain of unknown function (DUF1876) AbiEi_3_N PF17194.4 KIK55042.1 - 0.00013 22.0 2.0 17 5.5 0.0 5.9 4 3 2 6 6 6 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain UPF0147 PF03685.13 KIK55042.1 - 0.00088 19.3 0.0 45 4.2 0.0 5.5 4 2 2 6 6 6 0 Uncharacterised protein family (UPF0147) TPR_16 PF13432.6 KIK55042.1 - 0.00091 19.8 13.7 5.7 7.7 0.0 7.5 8 2 1 9 9 7 1 Tetratricopeptide repeat Mo25 PF08569.11 KIK55042.1 - 0.016 14.6 0.7 1.9 7.7 0.0 3.6 4 2 0 4 4 4 0 Mo25-like HsbA PF12296.8 KIK55042.1 - 0.023 15.1 0.2 7.7 7.0 0.0 3.5 4 0 0 4 4 4 0 Hydrophobic surface binding protein A TPR_21 PF09976.9 KIK55042.1 - 0.031 14.0 6.2 9.8 5.8 0.0 5.2 3 2 1 5 5 5 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 KIK55042.1 - 0.05 13.3 0.1 1.4e+02 2.3 0.0 5.3 6 0 0 6 6 6 0 TPR repeat ANAPC3 PF12895.7 KIK55042.1 - 0.71 10.1 18.9 42 4.5 0.2 7.7 3 2 6 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 UCH PF00443.29 KIK55043.1 - 1.3e-39 136.3 0.0 1.9e-39 135.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK55043.1 - 2.1e-10 40.7 0.0 0.0015 18.2 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase PNISR PF15996.5 KIK55043.1 - 3.2 8.0 10.4 4.9 7.4 1.4 2.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Bin3 PF06859.12 KIK55044.1 - 5.7e-35 120.2 0.0 8.3e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KIK55044.1 - 1.7e-13 50.6 0.0 4.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KIK55044.1 - 7e-13 49.1 0.0 9.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KIK55044.1 - 1.4e-12 47.7 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK55044.1 - 8.1e-10 39.2 0.0 0.0002 21.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIK55044.1 - 2.3e-09 37.9 0.0 0.00052 20.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KIK55044.1 - 0.00012 21.6 0.0 0.00052 19.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KIK55044.1 - 0.00018 20.9 0.3 0.24 10.6 0.1 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase MTS PF05175.14 KIK55044.1 - 0.00059 19.4 0.0 0.0025 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KIK55044.1 - 0.0007 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK55044.1 - 0.0015 18.0 0.0 0.0049 16.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.17 KIK55044.1 - 0.0017 17.8 0.0 0.84 9.0 0.0 2.1 2 0 0 2 2 2 2 Spermine/spermidine synthase domain Methyltransf_PK PF05891.12 KIK55044.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 KIK55044.1 - 0.017 14.5 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KIK55044.1 - 0.023 13.6 0.0 0.053 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KIK55044.1 - 0.028 14.4 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIK55044.1 - 0.042 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 KIK55044.1 - 0.085 12.8 0.1 2.6 8.0 0.0 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase p450 PF00067.22 KIK55045.1 - 3.4e-50 171.2 0.0 4.2e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 A2L_zn_ribbon PF08792.10 KIK55048.1 - 0.031 14.0 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain p450 PF00067.22 KIK55049.1 - 2.6e-48 164.9 0.0 3.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK55051.1 - 2.3e-51 170.7 28.5 2.6e-11 43.8 1.8 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55051.1 - 1.9e-18 66.5 1.3 0.00016 21.9 0.0 5.3 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK55051.1 - 1.4e-05 24.2 0.2 3.6 6.5 0.0 4.7 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK55051.1 - 0.00026 20.9 0.1 0.72 9.7 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK55051.1 - 0.0073 16.2 3.1 1.1 9.2 0.4 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK55051.1 - 0.011 14.6 1.2 6.4 5.4 0.2 3.8 1 1 0 3 3 3 0 Nup133 N terminal like IKI3 PF04762.12 KIK55051.1 - 0.018 13.0 1.4 7 4.5 0.0 2.9 2 1 0 3 3 3 0 IKI3 family DPPIV_N PF00930.21 KIK55051.1 - 0.093 11.5 1.8 1.6 7.4 0.1 2.7 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cellulase PF00150.18 KIK55052.1 - 4.4e-50 170.7 0.0 5.2e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK55052.1 - 3.1e-13 49.4 8.3 3.1e-13 49.4 8.3 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KIK55053.1 - 3e-05 24.5 0.0 0.00018 21.9 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PRIMA1 PF16101.5 KIK55053.1 - 0.88 9.6 4.5 2.1 8.4 4.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Aminotran_1_2 PF00155.21 KIK55054.1 - 3.5e-61 207.4 0.0 4e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK55054.1 - 0.042 12.4 0.0 0.086 11.3 0.0 1.6 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIK55054.1 - 0.1 11.6 0.0 0.26 10.2 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V F-box-like PF12937.7 KIK55055.1 - 0.022 14.6 0.7 0.08 12.9 0.1 2.2 2 0 0 2 2 2 0 F-box-like MULE PF10551.9 KIK55057.1 - 2.1e-05 24.8 0.1 3.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 MULE transposase domain F_actin_cap_B PF01115.17 KIK55061.1 - 1.1e-44 152.8 0.0 3.8e-44 151.1 0.0 1.7 1 1 0 1 1 1 1 F-actin capping protein, beta subunit DUF4018 PF13210.6 KIK55067.1 - 0.025 14.3 1.6 0.034 13.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Presenilin PF01080.17 KIK55067.1 - 0.26 10.0 2.4 0.27 10.0 2.4 1.0 1 0 0 1 1 1 0 Presenilin F_actin_cap_B PF01115.17 KIK55069.1 - 2.1e-49 168.3 0.5 2.5e-47 161.6 0.5 2.1 1 1 0 1 1 1 1 F-actin capping protein, beta subunit eIF3_subunit PF08597.10 KIK55075.1 - 1.5e-62 211.7 18.2 1.7e-62 211.5 18.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.8 KIK55075.1 - 0.021 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) COQ9 PF08511.11 KIK55076.1 - 4.7e-12 45.5 0.0 7.4e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 COQ9 His_Phos_1 PF00300.22 KIK55076.1 - 0.047 13.4 0.1 0.52 10.0 0.0 2.4 1 1 2 3 3 3 0 Histidine phosphatase superfamily (branch 1) DnaJ_C PF01556.18 KIK55077.1 - 4.5e-39 133.9 0.4 6e-39 133.5 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK55077.1 - 1.6e-27 95.4 1.6 2.6e-27 94.7 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain Retrotran_gag_2 PF14223.6 KIK55079.1 - 1.7e-08 34.2 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KIK55079.1 - 0.38 10.5 3.3 0.81 9.5 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Keratin_2_head PF16208.5 KIK55082.1 - 0.36 11.0 6.3 23 5.1 0.1 3.1 3 0 0 3 3 3 0 Keratin type II head F_actin_cap_B PF01115.17 KIK55084.1 - 2.1e-55 188.0 0.1 2.3e-55 187.8 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Adeno_PX PF05829.12 KIK55087.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Presenilin PF01080.17 KIK55087.1 - 0.15 10.8 1.2 0.17 10.6 1.2 1.0 1 0 0 1 1 1 0 Presenilin Retrotran_gag_2 PF14223.6 KIK55090.1 - 1.6e-11 44.0 0.5 2.3e-11 43.5 0.5 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PKcGMP_CC PF16808.5 KIK55095.1 - 5.4e-05 23.0 6.1 0.035 14.0 2.3 2.9 2 1 1 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 KIK55095.1 - 0.00027 20.5 4.0 0.00032 20.3 4.0 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK55095.1 - 0.00054 19.0 5.4 0.00063 18.7 5.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KIK55095.1 - 0.00054 19.8 1.9 0.00061 19.7 1.9 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Peptidase_S49_N PF08496.10 KIK55095.1 - 0.0022 18.0 0.4 0.0026 17.8 0.4 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF641 PF04859.12 KIK55095.1 - 0.0039 17.5 5.8 0.098 13.0 0.3 2.1 1 1 1 2 2 2 2 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 KIK55095.1 - 0.0039 17.5 10.1 0.41 11.0 3.1 2.4 1 1 2 3 3 3 2 Csm1 N-terminal domain LRS4 PF10422.9 KIK55095.1 - 0.0046 16.6 3.8 0.005 16.4 3.8 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 MAD PF05557.13 KIK55095.1 - 0.0062 15.0 4.2 0.014 13.8 4.3 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein Sec2p PF06428.11 KIK55095.1 - 0.0086 16.0 7.4 0.015 15.2 1.9 2.1 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p ADIP PF11559.8 KIK55095.1 - 0.015 15.3 6.1 0.046 13.8 5.6 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 KIK55095.1 - 0.023 14.5 6.7 0.027 14.3 6.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CC2-LZ PF16516.5 KIK55095.1 - 0.035 14.5 7.3 0.14 12.5 2.7 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc42p PF11544.8 KIK55095.1 - 0.047 13.7 1.7 0.35 10.9 0.1 2.4 1 1 1 2 2 2 0 Spindle pole body component Spc42p Phage_GP20 PF06810.11 KIK55095.1 - 0.047 13.5 6.9 0.75 9.6 0.7 2.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 KIK55095.1 - 0.051 13.6 0.4 0.051 13.6 0.4 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 KIK55095.1 - 0.055 12.7 2.4 0.064 12.5 2.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 KIK55095.1 - 0.065 13.2 6.9 0.74 9.8 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding XLF PF09302.11 KIK55095.1 - 0.068 13.3 3.1 0.55 10.4 0.1 2.1 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF16 PF01519.16 KIK55095.1 - 0.076 13.5 3.5 0.12 12.8 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1732 PF08340.11 KIK55095.1 - 0.082 12.9 1.5 0.45 10.5 0.4 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1732) Lebercilin PF15619.6 KIK55095.1 - 0.098 12.3 7.3 0.38 10.4 7.3 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KIK55095.1 - 0.1 11.9 8.4 0.24 10.7 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 KIK55095.1 - 0.13 12.8 9.8 2.8 8.6 10.2 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 KIK55095.1 - 0.22 11.9 7.2 20 5.6 0.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Cnn_1N PF07989.11 KIK55095.1 - 0.3 11.3 5.2 0.37 11.0 0.6 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 KIK55095.1 - 0.34 11.0 2.3 0.66 10.0 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.6 KIK55095.1 - 0.41 10.0 8.4 4.8 6.5 2.3 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4349 PF14257.6 KIK55095.1 - 0.56 9.6 4.7 0.68 9.3 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HR1 PF02185.16 KIK55097.1 - 0.72 10.0 4.2 0.26 11.4 0.9 1.9 2 0 0 2 2 2 0 Hr1 repeat DUF202 PF02656.15 KIK55099.1 - 6.1e-13 49.0 2.9 6.1e-13 49.0 2.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF5134 PF17197.4 KIK55099.1 - 0.0032 17.4 0.3 0.0049 16.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) Vac_ImportDeg PF09783.9 KIK55100.1 - 0.18 11.6 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein Pro_isomerase PF00160.21 KIK55101.1 - 6.7e-48 162.9 0.0 7.5e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.20 KIK55102.1 - 2.5e-121 405.2 0.0 2.9e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK55102.1 - 2.3e-13 50.0 0.0 1.3e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK55102.1 - 8.2e-05 22.8 0.0 0.47 10.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK55102.1 - 0.00018 21.1 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 Ras family TniB PF05621.11 KIK55102.1 - 0.0067 15.8 0.1 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 KIK55102.1 - 0.0071 16.1 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KIK55102.1 - 0.0094 15.3 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KIK55102.1 - 0.076 12.8 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyt-b5 PF00173.28 KIK55103.1 - 2.4e-12 46.8 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR_4 PF15892.5 KIK55104.1 - 1.9e-58 198.0 0.3 2.6e-58 197.6 0.3 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member HLH PF00010.26 KIK55105.1 - 5.7e-07 29.4 0.0 3.2e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4407 PF14362.6 KIK55105.1 - 0.11 11.8 0.6 0.13 11.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) THUMP PF02926.17 KIK55106.1 - 6e-15 55.6 0.1 1.5e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 THUMP domain TEA PF01285.18 KIK55107.1 - 1.9e-23 82.3 0.0 4e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain DnaJ PF00226.31 KIK55108.1 - 4.3e-18 65.2 1.8 4.3e-18 65.2 1.8 1.9 2 0 0 2 2 2 1 DnaJ domain Ni_hydr_CYTB PF01292.20 KIK55108.1 - 0.056 13.0 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DNA_pol3_delta2 PF13177.6 KIK55109.1 - 3.6e-13 49.6 0.3 6.9e-13 48.7 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KIK55109.1 - 8.2e-06 26.3 0.6 1.9e-05 25.1 0.6 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KIK55109.1 - 0.00076 19.3 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KIK55109.1 - 0.0025 18.2 0.0 0.0072 16.7 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 KIK55109.1 - 0.0036 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIK55109.1 - 0.0044 17.4 0.2 0.021 15.2 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK55109.1 - 0.016 15.5 1.7 0.6 10.4 1.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK55109.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KIK55109.1 - 0.13 12.0 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIK55109.1 - 0.14 12.3 0.2 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain HD PF01966.22 KIK55110.1 - 0.00089 19.5 0.3 0.0039 17.4 0.3 1.9 1 1 0 1 1 1 1 HD domain Zip PF02535.22 KIK55111.1 - 4.7e-46 157.6 15.3 2.4e-38 132.2 6.9 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF5368 PF17336.2 KIK55111.1 - 0.061 13.5 0.3 0.17 12.1 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5368) DUF5379 PF17350.2 KIK55111.1 - 0.21 11.9 7.9 2.9 8.2 0.1 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5379) NUDIX PF00293.28 KIK55112.1 - 2.1e-12 47.2 0.5 2.9e-12 46.8 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain DAO PF01266.24 KIK55114.1 - 2.7e-47 162.0 0.0 3.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KIK55114.1 - 2e-45 153.7 0.1 3.7e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KIK55114.1 - 6.7e-11 41.9 0.6 1.1e-05 24.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIK55114.1 - 6.4e-08 32.4 1.4 1e-06 28.4 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK55114.1 - 1.1e-05 24.9 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KIK55114.1 - 3.1e-05 23.2 0.1 0.0021 17.2 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIK55114.1 - 0.00013 21.4 0.5 0.0003 20.1 0.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK55114.1 - 0.0026 17.9 1.3 0.0059 16.8 0.4 2.1 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK55114.1 - 0.01 14.6 0.9 0.017 13.9 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK55114.1 - 0.037 13.3 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK55114.1 - 0.063 12.5 0.9 0.13 11.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KIK55114.1 - 0.063 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIK55114.1 - 0.13 12.8 2.6 0.18 12.4 0.5 2.3 2 1 1 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase ECH_1 PF00378.20 KIK55115.1 - 1.6e-35 122.6 0.0 2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK55115.1 - 3.4e-17 63.0 0.0 8e-17 61.7 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF4786 PF16027.5 KIK55116.1 - 0.033 14.8 0.7 0.047 14.3 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4786) Cauli_VI PF01693.16 KIK55117.1 - 0.00034 20.8 0.7 0.00083 19.6 0.7 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin PKcGMP_CC PF16808.5 KIK55117.1 - 0.23 11.3 1.1 0.42 10.5 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sporozoite_P67 PF05642.11 KIK55118.1 - 0.011 13.9 0.2 0.012 13.7 0.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 KIK55118.1 - 6.2 6.4 10.6 8.8 5.9 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KDZ PF18758.1 KIK55120.1 - 6.7e-27 94.5 1.1 2.7e-25 89.3 0.8 2.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK55120.1 - 1.4e-20 73.4 1.3 4.5e-20 71.8 1.3 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF1623 PF07785.11 KIK55120.1 - 0.085 13.0 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) ChitinaseA_N PF08329.10 KIK55120.1 - 0.11 12.2 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Flavi_NS1 PF00948.21 KIK55121.1 - 0.21 10.5 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 MAP65_ASE1 PF03999.12 KIK55122.1 - 0.015 14.0 4.5 0.019 13.7 4.5 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DivIC PF04977.15 KIK55122.1 - 0.077 12.8 13.1 0.83 9.5 2.6 3.3 2 1 1 3 3 3 0 Septum formation initiator Fez1 PF06818.15 KIK55122.1 - 0.095 13.1 9.4 3.2 8.2 10.0 1.8 1 1 1 2 2 2 0 Fez1 COMP PF11598.8 KIK55122.1 - 0.15 12.6 3.3 11 6.6 0.3 2.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FAM76 PF16046.5 KIK55122.1 - 0.16 11.3 3.9 0.35 10.2 3.6 1.6 1 1 0 1 1 1 0 FAM76 protein Pox_A_type_inc PF04508.12 KIK55122.1 - 0.32 10.9 4.4 6.5 6.8 0.1 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Spc29 PF17082.5 KIK55122.1 - 0.64 9.8 7.1 0.99 9.2 4.4 2.3 1 1 2 3 3 3 0 Spindle Pole Component 29 DUF4337 PF14235.6 KIK55122.1 - 1.2 9.2 5.6 1.8 8.6 5.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) FlxA PF14282.6 KIK55122.1 - 3.9 7.5 12.0 8.7 6.4 0.1 3.0 2 1 1 3 3 3 0 FlxA-like protein TSC22 PF01166.18 KIK55122.1 - 4.3 7.7 14.2 4.3 7.7 0.1 4.0 2 1 3 5 5 5 0 TSC-22/dip/bun family AKAP7_NLS PF10469.9 KIK55124.1 - 0.0025 17.7 1.3 0.066 13.1 0.2 2.1 1 1 1 2 2 2 1 AKAP7 2'5' RNA ligase-like domain HTH_6 PF01418.17 KIK55124.1 - 0.0036 17.3 0.1 1.7 8.7 0.0 3.1 3 1 1 4 4 4 1 Helix-turn-helix domain, rpiR family R3H PF01424.22 KIK55124.1 - 0.0062 16.5 4.6 7.1 6.7 0.0 4.4 5 0 0 5 5 5 2 R3H domain DsrC PF04358.13 KIK55124.1 - 0.0065 17.0 0.3 5.6 7.5 0.0 2.3 2 0 0 2 2 2 2 DsrC like protein Pre-PUA PF17832.1 KIK55124.1 - 0.019 15.6 2.9 4.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Pre-PUA-like domain Baculo_p48 PF04878.13 KIK55124.1 - 0.086 11.8 0.2 7.9 5.3 0.0 2.0 1 1 0 2 2 2 0 Baculovirus P48 protein Peptidase_C93 PF06035.11 KIK55124.1 - 0.092 12.5 0.0 6.8 6.4 0.0 2.4 1 1 1 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Telomere_reg-2 PF10193.9 KIK55124.1 - 0.15 12.5 5.3 10 6.6 0.3 3.1 2 2 1 3 3 3 0 Telomere length regulation protein IreB PF06135.12 KIK55124.1 - 0.17 12.1 3.6 11 6.3 0.3 2.5 2 0 0 2 2 2 0 IreB regulatory phosphoprotein RNA_GG_bind PF10258.9 KIK55125.1 - 0.024 14.7 0.1 0.06 13.4 0.1 1.7 1 0 0 1 1 1 0 PHAX RNA-binding domain HMG_box_2 PF09011.10 KIK55125.1 - 0.026 15.1 0.3 0.063 13.9 0.3 1.7 1 0 0 1 1 1 0 HMG-box domain PEP-utilisers_N PF05524.13 KIK55125.1 - 0.027 14.6 0.9 0.6 10.3 0.1 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal ECH_1 PF00378.20 KIK55126.1 - 3.6e-27 95.3 0.0 4.6e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK55126.1 - 1.7e-13 50.8 0.0 4.2e-13 49.5 0.0 1.4 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF5068 PF16781.5 KIK55128.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) ECH_1 PF00378.20 KIK55129.1 - 6e-28 97.8 0.0 7.2e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK55129.1 - 2e-11 44.0 0.0 9.4e-11 41.8 0.0 1.7 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Glyco_transf_11 PF01531.16 KIK55130.1 - 0.078 12.2 0.0 0.098 11.9 0.0 1.2 1 1 0 1 1 1 0 Glycosyl transferase family 11 DpnD-PcfM PF14207.6 KIK55130.1 - 0.17 11.8 1.3 0.24 11.3 0.6 1.6 1 1 0 1 1 1 0 DpnD/PcfM-like protein RAI1 PF08652.11 KIK55131.1 - 2.7e-21 75.5 0.0 7.7e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Sugar_tr PF00083.24 KIK55133.1 - 8.3e-109 364.4 32.6 9.6e-109 364.2 32.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK55133.1 - 6.6e-24 84.5 47.3 2.7e-19 69.3 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyt-b5 PF00173.28 KIK55134.1 - 3.5e-18 65.5 0.0 4.9e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ECH_1 PF00378.20 KIK55136.1 - 9.4e-34 116.8 0.0 1.1e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK55136.1 - 6.3e-17 62.1 0.0 7.2e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2927 PF11150.8 KIK55136.1 - 0.099 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) zf-HIT PF04438.16 KIK55137.1 - 1.9 8.5 6.1 6.1 6.8 6.1 1.8 1 1 0 1 1 1 0 HIT zinc finger NmrA PF05368.13 KIK55138.1 - 1.8e-18 67.0 0.1 2.6e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55138.1 - 8.2e-12 45.4 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 KIK55138.1 - 4.6e-05 24.2 0.0 6.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KIK55138.1 - 0.0011 19.5 0.0 0.0026 18.3 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIK55138.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK55138.1 - 0.03 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KIK55138.1 - 0.11 13.1 0.0 1.1 9.9 0.0 2.0 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIK55138.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein TauD PF02668.16 KIK55139.1 - 2.6e-58 197.9 0.2 3.2e-58 197.6 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.27 KIK55140.1 - 3.5e-15 55.3 3.0 6.3e-15 54.5 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger Actin PF00022.19 KIK55142.1 - 7.1e-40 136.9 0.0 1.3e-37 129.4 0.0 3.2 1 1 0 1 1 1 1 Actin Med22 PF06179.12 KIK55143.1 - 2.9e-18 66.0 4.4 3.8e-18 65.6 4.4 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex MIR PF02815.19 KIK55143.1 - 0.0011 18.8 0.2 0.0014 18.5 0.2 1.1 1 0 0 1 1 1 1 MIR domain FlgT_N PF16548.5 KIK55143.1 - 0.029 14.9 2.0 0.055 14.0 2.0 1.4 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain ICL PF00463.21 KIK55143.1 - 0.051 12.0 0.0 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 Isocitrate lyase family Pkinase_Tyr PF07714.17 KIK55144.1 - 2.5e-40 138.4 0.0 3.9e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK55144.1 - 5.7e-34 117.7 0.0 1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain bZIP_1 PF00170.21 KIK55144.1 - 1.7e-07 31.3 8.6 3.4e-07 30.3 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK55144.1 - 4.8e-05 23.4 10.2 8.7e-05 22.5 10.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Uds1 PF15456.6 KIK55144.1 - 0.014 15.5 0.5 0.033 14.4 0.5 1.6 1 0 0 1 1 1 0 Up-regulated During Septation bZIP_Maf PF03131.17 KIK55144.1 - 0.016 15.7 3.1 0.13 12.8 3.6 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor APH PF01636.23 KIK55144.1 - 0.04 13.8 0.2 0.12 12.3 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family bZIP_1 PF00170.21 KIK55145.1 - 0.00011 22.2 7.4 0.0002 21.4 7.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK55145.1 - 0.00021 21.3 9.1 0.00035 20.6 9.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Atg14 PF10186.9 KIK55146.1 - 0.17 10.9 1.5 0.31 10.1 1.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Arrestin_N PF00339.29 KIK55147.1 - 7.2e-07 29.4 0.3 4.3e-06 26.8 0.3 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 KIK55148.1 - 1.6e-06 28.3 0.0 0.00011 22.3 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIK55148.1 - 0.11 13.0 0.0 18 5.8 0.0 2.8 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIK55150.1 - 9e-09 35.5 0.1 8.9e-06 25.8 0.1 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KIK55150.1 - 0.052 12.5 0.0 0.083 11.9 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Chol_subst-bind PF09129.11 KIK55150.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Methyltransf_16 PF10294.9 KIK55151.1 - 3.5e-26 92.0 0.0 5.1e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase N6-adenineMlase PF10237.9 KIK55151.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Mito_carr PF00153.27 KIK55152.1 - 1.9e-56 188.0 0.5 4.8e-19 68.1 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.21 KIK55153.1 - 1.4e-101 340.7 0.0 1.7e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Amidase OPT PF03169.15 KIK55154.1 - 6.2e-143 477.7 38.0 7e-143 477.5 38.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PX PF00787.24 KIK55155.1 - 0.0043 17.0 0.1 0.027 14.5 0.0 2.4 2 1 0 2 2 2 1 PX domain Lipase_3 PF01764.25 KIK55156.1 - 1.3e-06 28.3 0.0 7.8e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK55156.1 - 0.019 15.6 0.2 0.039 14.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Trehalase PF01204.18 KIK55157.1 - 1.8e-160 535.2 0.0 2.2e-160 534.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KIK55157.1 - 4e-15 55.2 0.1 6.8e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ATG22 PF11700.8 KIK55158.1 - 1.7e-106 356.7 23.6 9.1e-105 351.0 23.6 2.2 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like TssN PF17555.2 KIK55158.1 - 3.6 6.9 12.8 0.49 9.7 5.8 2.5 1 1 0 2 2 2 0 Type VI secretion system, TssN Arrestin_N PF00339.29 KIK55159.1 - 0.043 13.9 0.2 1 9.4 0.2 2.3 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KIK55159.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 DivIC PF04977.15 KIK55160.1 - 0.05 13.4 0.7 0.12 12.2 0.2 1.8 2 0 0 2 2 2 0 Septum formation initiator Val_tRNA-synt_C PF10458.9 KIK55160.1 - 0.066 13.5 3.9 0.44 10.9 2.2 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF3196 PF11428.8 KIK55160.1 - 0.096 12.2 0.0 0.98 8.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3196) TPX2 PF06886.11 KIK55160.1 - 0.14 12.4 3.4 0.26 11.6 3.4 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) BMFP PF04380.13 KIK55160.1 - 0.16 12.5 4.8 17 6.0 0.0 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity Mitofilin PF09731.9 KIK55161.1 - 9.6e-108 361.7 31.7 8.9e-107 358.5 31.7 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Ribosomal_L31e PF01198.19 KIK55161.1 - 0.069 13.4 5.5 0.89 9.8 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L31e Hpt PF01627.23 KIK55161.1 - 5 7.5 8.7 1.1 9.5 0.2 3.6 2 1 1 3 3 3 0 Hpt domain DUF2894 PF11445.8 KIK55161.1 - 8.7 6.8 15.2 1.4 9.3 5.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2894) VRR_NUC PF08774.11 KIK55162.1 - 2.2e-20 72.7 0.1 6.6e-20 71.2 0.1 1.8 1 0 0 1 1 1 1 VRR-NUC domain DUF2249 PF10006.9 KIK55162.1 - 0.14 12.1 0.3 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Nucleoporin_FG PF13634.6 KIK55164.1 - 1.7e-30 105.7 110.9 3.6e-12 47.0 39.6 4.5 1 1 3 4 4 4 4 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 KIK55164.1 - 0.0011 17.6 54.7 0.0035 16.0 54.6 2.3 1 1 0 1 1 1 1 Nucleoporin FG repeated region DUF4470 PF14737.6 KIK55165.1 - 1.3e-20 73.4 0.0 6.1e-20 71.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) DUF1010 PF06231.11 KIK55165.1 - 0.042 14.4 0.1 18 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) zf-MYND PF01753.18 KIK55166.1 - 1.7e-08 34.4 12.9 1.7e-08 34.4 12.9 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIK55166.1 - 1.3 9.4 11.3 3 8.2 11.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KIK55166.1 - 1.4 8.9 10.1 3.3 7.6 10.1 1.6 1 0 0 1 1 1 0 HIT zinc finger zf-C2H2_3 PF13878.6 KIK55166.1 - 3.3 7.6 8.0 2.6 7.9 5.3 2.1 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF4470 PF14737.6 KIK55168.1 - 4.7e-25 87.6 0.0 1.1e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIK55168.1 - 7e-11 42.0 15.7 1.7e-10 40.8 15.7 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK55168.1 - 1.6 9.1 18.1 0.24 11.7 13.0 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Ctf8 PF09696.10 KIK55170.1 - 1.6e-15 57.7 0.7 3.3e-14 53.4 0.7 2.5 1 1 0 1 1 1 1 Ctf8 TamB PF04357.13 KIK55170.1 - 0.032 13.5 0.1 0.037 13.3 0.1 1.1 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex Augurin PF15187.6 KIK55173.1 - 0.0041 17.3 0.1 0.0063 16.7 0.1 1.3 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 TPR_11 PF13414.6 KIK55174.1 - 0.00071 19.2 1.3 0.00087 18.9 1.3 1.1 1 0 0 1 1 1 1 TPR repeat PAS_8 PF13188.7 KIK55174.1 - 0.014 15.4 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 PAS domain TPR_17 PF13431.6 KIK55174.1 - 0.029 14.7 1.1 0.051 14.0 1.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55174.1 - 0.034 14.0 4.8 0.077 12.9 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PAS_9 PF13426.7 KIK55174.1 - 0.067 13.4 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 PAS domain Augurin PF15187.6 KIK55175.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 TPR_11 PF13414.6 KIK55176.1 - 0.00072 19.2 0.2 0.00098 18.8 0.2 1.2 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 KIK55176.1 - 0.00096 19.1 2.3 0.0013 18.7 0.2 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55176.1 - 0.0011 18.7 2.4 0.015 15.1 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat PAS_8 PF13188.7 KIK55176.1 - 0.058 13.4 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 KIK55176.1 - 0.077 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 PAS domain Fra10Ac1 PF09725.9 KIK55178.1 - 1.7e-24 86.3 0.6 1.9e-24 86.1 0.6 1.0 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 AAA_12 PF13087.6 KIK55179.1 - 7.7e-55 185.6 0.0 1.3e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK55179.1 - 2.1e-25 90.0 1.4 2.7e-19 70.0 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 KIK55179.1 - 6.1e-11 42.8 0.6 2.9e-10 40.7 0.6 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK55179.1 - 6.9e-08 32.4 0.1 1.3e-05 25.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KIK55179.1 - 3e-05 23.7 0.4 7.7e-05 22.4 0.3 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KIK55179.1 - 0.0096 15.7 0.0 7.5 6.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase XhlA PF10779.9 KIK55179.1 - 0.042 14.1 0.1 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 Haemolysin XhlA Laminin_I PF06008.14 KIK55179.1 - 0.042 13.6 2.1 0.066 12.9 2.1 1.2 1 0 0 1 1 1 0 Laminin Domain I AAA PF00004.29 KIK55179.1 - 0.053 14.0 0.3 0.17 12.3 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIK55179.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Syntaxin-6_N PF09177.11 KIK55179.1 - 0.11 13.1 0.9 0.24 11.9 0.9 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Pinin_SDK_N PF04697.13 KIK55179.1 - 0.13 12.9 1.5 0.33 11.6 1.5 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region AAA_6 PF12774.7 KIK55179.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Occludin_ELL PF07303.13 KIK55179.1 - 0.51 11.1 3.4 1.3 9.8 3.4 1.6 1 0 0 1 1 1 0 Occludin homology domain ZapB PF06005.12 KIK55179.1 - 2.6 8.6 10.7 0.15 12.5 4.9 2.0 2 0 0 2 2 1 0 Cell division protein ZapB eIF-6 PF01912.18 KIK55181.1 - 1.1e-82 276.2 1.4 1.2e-82 276.0 0.2 1.6 2 0 0 2 2 2 1 eIF-6 family Methyltransf_28 PF02636.17 KIK55182.1 - 4.5e-64 216.6 0.0 5.3e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase VSP PF03302.13 KIK55183.1 - 5.5e-05 22.2 14.5 7.3e-05 21.8 14.5 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Dicty_REP PF05086.12 KIK55183.1 - 5.3 4.9 18.0 6.6 4.6 18.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.7 KIK55184.1 - 0.00094 19.0 0.0 0.0071 16.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like PS_Dcarbxylase PF02666.15 KIK55185.1 - 9.4e-71 237.5 0.0 7.5e-69 231.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 KIK55185.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 MNLL subunit PTPlike_phytase PF14566.6 KIK55186.1 - 1.7e-137 453.8 0.0 5.4e-47 159.8 0.0 4.3 4 0 0 4 4 4 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIK55186.1 - 0.0011 18.6 0.0 0.73 9.4 0.0 3.1 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Nairo_nucleo PF02477.15 KIK55186.1 - 0.0088 14.9 0.0 0.032 13.1 0.0 1.8 2 0 0 2 2 2 1 Nucleocapsid N protein DSPc PF00782.20 KIK55186.1 - 0.018 14.8 0.0 6.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Ost5 PF05251.12 KIK55188.1 - 0.05 13.9 2.3 0.073 13.3 2.3 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 CxC4 PF18717.1 KIK55191.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases DUF1160 PF06648.11 KIK55192.1 - 0.052 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Herpes_IE68 PF02479.16 KIK55194.1 - 0.072 12.7 0.1 0.083 12.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein TM_helix PF05552.12 KIK55195.1 - 0.027 14.4 0.2 0.044 13.8 0.2 1.3 1 0 0 1 1 1 0 Conserved TM helix Antimicrobial_2 PF08023.12 KIK55195.1 - 0.36 11.4 4.9 6.8 7.3 4.9 2.3 1 1 0 1 1 1 0 Frog antimicrobial peptide Cu PF17563.2 KIK55195.1 - 5 7.4 8.1 65 3.9 8.1 2.2 1 1 0 1 1 1 0 Cupiennin RAP PF08373.10 KIK55196.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 RAP domain Sec8_exocyst PF04048.14 KIK55197.1 - 0.031 14.2 2.2 7.6 6.4 0.0 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain SKA2 PF16740.5 KIK55197.1 - 0.68 9.7 5.8 0.27 11.1 3.0 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 NACHT PF05729.12 KIK55200.1 - 5.2e-10 39.5 0.1 1.1e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK55200.1 - 0.00041 20.8 0.0 0.0007 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KIK55200.1 - 0.0016 17.8 0.1 0.0041 16.4 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 KIK55200.1 - 0.0025 17.1 0.0 0.016 14.4 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KIK55200.1 - 0.0028 17.7 0.3 0.18 11.9 0.0 3.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK55200.1 - 0.0038 17.6 0.0 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Zfx_Zfy_act PF04704.13 KIK55200.1 - 0.0045 16.2 0.3 0.0056 15.8 0.3 1.1 1 0 0 1 1 1 1 Zfx / Zfy transcription activation region AAA_22 PF13401.6 KIK55200.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KIK55200.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit APS_kinase PF01583.20 KIK55200.1 - 0.074 13.0 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.14 KIK55200.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase TsaE PF02367.17 KIK55200.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3433 PF11915.8 KIK55201.1 - 1.5e-15 57.4 28.0 2.5e-15 56.7 1.2 4.8 5 1 0 5 5 5 2 Protein of unknown function (DUF3433) Sugar_tr PF00083.24 KIK55202.1 - 3.5e-119 398.6 20.6 4.2e-119 398.4 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK55202.1 - 2.1e-17 63.1 43.3 7.7e-15 54.7 19.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 KIK55202.1 - 0.23 11.1 0.6 1.7 8.2 0.3 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KIK55203.1 - 1.2e-19 70.4 51.3 2.9e-13 49.5 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 KIK55204.1 - 2.4e-12 46.6 9.5 8.7e-08 32.2 1.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK55204.1 - 1.6e-10 40.9 8.5 1.7e-06 28.4 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK55204.1 - 5.5e-06 26.6 13.0 0.00012 22.4 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KIK55204.1 - 9.6e-06 25.8 0.4 3.6e-05 24.0 0.1 2.1 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK55204.1 - 3.7e-05 23.9 0.3 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIK55204.1 - 0.00034 20.4 4.0 0.019 14.9 1.0 2.5 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIK55204.1 - 0.00038 20.4 0.1 0.00038 20.4 0.1 2.2 3 0 0 3 3 3 1 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KIK55204.1 - 0.0012 19.3 0.7 0.0061 17.0 0.2 2.3 2 1 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KIK55204.1 - 0.002 17.8 3.0 1.1 9.1 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KIK55204.1 - 0.0024 18.1 5.9 1.2 9.4 0.9 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIK55204.1 - 0.012 15.9 1.8 0.09 13.1 0.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 KIK55204.1 - 0.065 13.2 1.0 7.7 6.5 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KIK55204.1 - 0.073 12.9 1.9 0.6 10.0 0.2 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 KIK55204.1 - 0.095 12.5 0.4 2.4 8.1 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif FOXP-CC PF16159.5 KIK55204.1 - 0.1 13.2 1.0 1 10.1 0.2 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain CpXC PF14353.6 KIK55204.1 - 0.12 12.4 0.8 3.9 7.5 0.7 2.0 1 1 0 1 1 1 0 CpXC protein zf_UBZ PF18439.1 KIK55204.1 - 0.13 11.9 1.2 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KIK55204.1 - 0.14 12.2 2.3 7.1 6.7 2.3 2.2 1 1 0 1 1 1 0 BED zinc finger UBZ_FAAP20 PF15750.5 KIK55204.1 - 0.24 11.4 2.7 0.59 10.1 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger FYDLN_acid PF09538.10 KIK55204.1 - 1.4 9.6 2.8 31 5.3 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) F-box-like PF12937.7 KIK55206.1 - 4.9e-09 35.9 2.4 6.8e-09 35.5 1.7 1.7 1 1 0 1 1 1 1 F-box-like Nitroreductase PF00881.24 KIK55206.1 - 0.013 15.6 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Nitroreductase family DUF5063 PF16702.5 KIK55206.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) F-box PF00646.33 KIK55206.1 - 0.038 13.9 2.4 0.51 10.3 2.4 2.3 1 1 0 1 1 1 0 F-box domain DivIC PF04977.15 KIK55206.1 - 0.09 12.6 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator zf-C2H2_jaz PF12171.8 KIK55208.1 - 3.5e-10 39.9 1.9 5.9e-10 39.2 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIK55208.1 - 0.01 16.2 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIK55208.1 - 0.014 15.7 1.2 0.026 14.9 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ADH_zinc_N PF00107.26 KIK55209.1 - 1.5e-13 50.9 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK55209.1 - 2.9e-08 33.6 0.4 9.6e-08 31.9 0.0 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK55209.1 - 0.00052 21.1 0.0 0.00085 20.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIK55211.1 - 1.1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK55211.1 - 1.8e-08 34.2 0.1 7.5e-08 32.2 0.0 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK55211.1 - 0.074 14.1 0.0 0.13 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NACHT PF05729.12 KIK55213.1 - 0.0067 16.4 1.0 0.0078 16.2 0.3 1.5 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 KIK55214.1 - 3.6e-21 75.6 9.8 3.8e-11 43.4 0.3 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK55214.1 - 1.2e-17 64.0 0.6 3.8e-06 27.4 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK55214.1 - 3.1e-14 51.7 0.4 0.0029 17.9 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KIK55214.1 - 1.3e-12 47.5 3.0 0.0004 20.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KIK55214.1 - 5.2e-11 42.6 3.0 0.00037 20.7 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) YajC PF02699.15 KIK55214.1 - 0.007 16.2 0.5 15 5.6 0.0 3.6 1 1 3 4 4 4 1 Preprotein translocase subunit RTC4 PF14474.6 KIK55214.1 - 0.087 13.0 3.9 1.4 9.1 0.2 2.8 1 1 2 3 3 3 0 RTC4-like domain RP-C_C PF11800.8 KIK55214.1 - 0.52 10.4 6.3 4.9 7.2 0.4 2.9 1 1 2 3 3 3 0 Replication protein C C-terminal region CD24 PF14984.6 KIK55214.1 - 7.9 6.8 10.3 53 4.2 0.1 3.9 4 0 0 4 4 4 0 CD24 protein Phage_GP20 PF06810.11 KIK55215.1 - 0.0056 16.5 7.1 0.25 11.1 1.3 2.3 1 1 1 2 2 2 2 Phage minor structural protein GP20 KASH_CCD PF14662.6 KIK55215.1 - 0.0076 16.1 11.0 0.014 15.3 11.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Peptidase_S49_N PF08496.10 KIK55215.1 - 0.0096 16.0 0.8 0.021 14.9 0.8 1.5 1 0 0 1 1 1 1 Peptidase family S49 N-terminal AAA_13 PF13166.6 KIK55215.1 - 0.011 14.5 3.5 0.014 14.1 3.5 1.1 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 KIK55215.1 - 0.016 15.7 13.3 0.019 15.4 11.4 1.8 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KIK55215.1 - 0.027 13.3 12.8 0.04 12.8 12.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 KIK55215.1 - 0.028 13.9 9.0 0.049 13.1 9.0 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4600 PF15372.6 KIK55215.1 - 0.033 14.6 6.1 0.058 13.8 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) TMF_DNA_bd PF12329.8 KIK55215.1 - 0.039 13.9 15.2 0.13 12.3 6.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 KIK55215.1 - 0.084 12.5 15.7 0.14 11.8 15.7 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Csm1_N PF18504.1 KIK55215.1 - 0.19 12.1 14.7 0.19 12.1 3.6 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain BRE1 PF08647.11 KIK55215.1 - 0.2 11.7 12.2 0.83 9.8 1.3 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Sec2p PF06428.11 KIK55215.1 - 0.23 11.4 13.1 0.044 13.8 2.7 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p YscO-like PF16789.5 KIK55215.1 - 0.27 11.2 11.3 0.43 10.6 11.3 1.2 1 0 0 1 1 1 0 YscO-like protein PKcGMP_CC PF16808.5 KIK55215.1 - 0.3 11.0 12.1 1.4 8.9 1.6 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 KIK55215.1 - 0.31 11.1 2.8 0.65 10.1 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KIK55215.1 - 0.33 11.1 19.0 1.9 8.7 6.4 2.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) LRS4 PF10422.9 KIK55215.1 - 0.45 10.1 8.3 0.75 9.3 8.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Spc42p PF11544.8 KIK55215.1 - 0.61 10.1 3.2 13 5.8 0.1 3.1 1 1 0 3 3 3 0 Spindle pole body component Spc42p MPS2 PF17060.5 KIK55215.1 - 0.82 8.9 5.5 1.3 8.2 5.5 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4407 PF14362.6 KIK55215.1 - 0.92 8.8 6.1 1.3 8.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaphilin PF15290.6 KIK55215.1 - 1 8.9 12.8 0.098 12.3 5.5 2.1 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Rho_Binding PF08912.11 KIK55215.1 - 1.2 10.0 10.0 2.5 9.0 2.5 2.4 2 0 0 2 2 2 0 Rho Binding Cnn_1N PF07989.11 KIK55215.1 - 1.9 8.7 9.0 1 9.5 1.4 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 KIK55215.1 - 2.2 8.5 11.6 1.3 9.2 1.3 2.9 2 1 1 3 3 3 0 bZIP transcription factor UPF0242 PF06785.11 KIK55215.1 - 2.2 8.4 13.5 0.53 10.3 9.8 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 KIK55215.1 - 2.7 8.3 10.7 13 6.1 7.7 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 KIK55215.1 - 3.2 5.6 5.2 4.2 5.2 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 KIK55215.1 - 4.4 8.0 11.3 12 6.6 2.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 KIK55215.1 - 7.2 6.7 13.8 4 7.5 8.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 KIK55215.1 - 8.7 5.1 14.3 20 3.9 14.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF745 PF05335.13 KIK55216.1 - 0.031 14.0 2.2 2.1 8.1 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF648 PF04890.13 KIK55216.1 - 0.039 13.7 0.2 0.056 13.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) PKcGMP_CC PF16808.5 KIK55216.1 - 1.1 9.2 7.7 5.5 6.9 0.3 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KIK55216.1 - 4.8 7.9 8.3 12 6.6 0.9 3.3 1 1 2 3 3 3 0 SlyX Ank_4 PF13637.6 KIK55218.1 - 2.3e-20 72.7 0.5 1.6e-08 34.9 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KIK55218.1 - 6.8e-17 61.1 4.6 0.00016 21.9 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KIK55218.1 - 9.7e-16 58.1 1.5 4.3e-13 49.6 0.4 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK55218.1 - 6.6e-15 53.7 0.3 0.0034 17.7 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK55218.1 - 4.1e-10 39.7 0.6 0.0015 18.8 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF4413 PF14372.6 KIK55220.1 - 0.13 12.6 0.4 0.25 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) His_Phos_1 PF00300.22 KIK55220.1 - 0.33 10.6 3.4 0.69 9.6 1.1 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) YfhD PF14151.6 KIK55221.1 - 0.047 13.8 1.7 0.25 11.5 1.7 2.3 1 0 0 1 1 1 0 YfhD-like protein DTHCT PF08070.11 KIK55221.1 - 0.13 13.0 10.7 0.54 11.0 10.4 2.2 1 1 0 1 1 1 0 DTHCT (NUC029) region Csm1_N PF18504.1 KIK55221.1 - 0.22 11.9 6.9 0.74 10.2 3.9 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain Rep_fac-A_3 PF08661.11 KIK55222.1 - 0.0034 17.7 0.0 0.0081 16.5 0.0 1.6 1 1 0 1 1 1 1 Replication factor A protein 3 Glyco_hydro_cc PF11790.8 KIK55227.1 - 0.016 14.8 0.1 0.028 14.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core Rpn3_C PF08375.11 KIK55227.1 - 0.18 12.2 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal NACHT PF05729.12 KIK55229.1 - 8.6e-07 29.0 0.0 2.9e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK55229.1 - 0.014 15.8 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK55229.1 - 0.015 15.3 0.0 0.064 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK55229.1 - 0.019 15.4 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KIK55229.1 - 0.025 14.0 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 KIK55229.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain ResIII PF04851.15 KIK55229.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KIK55229.1 - 0.051 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Ank_2 PF12796.7 KIK55230.1 - 2.6e-43 146.5 33.0 3.9e-11 43.4 1.7 4.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK55230.1 - 1.4e-32 111.7 8.4 4.9e-06 27.0 0.1 7.3 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK55230.1 - 7.9e-26 87.3 17.2 0.0099 16.3 0.0 9.5 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KIK55230.1 - 1.1e-20 73.1 25.4 0.017 15.5 0.1 9.1 8 1 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KIK55230.1 - 1.1e-10 41.5 14.8 0.018 15.3 0.8 6.1 4 1 1 6 6 6 4 Ankyrin repeats (many copies) Borealin PF10512.9 KIK55230.1 - 0.022 14.8 0.1 39 4.2 0.0 4.1 3 1 1 5 5 5 0 Cell division cycle-associated protein 8 Hema_HEFG PF02710.14 KIK55230.1 - 0.87 9.8 3.5 21 5.3 0.1 3.6 2 2 2 5 5 5 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein DUF1843 PF08898.10 KIK55230.1 - 7.4 7.2 10.3 8.9 6.9 0.2 4.4 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) CxC2 PF18803.1 KIK55231.1 - 1.3e-09 38.1 0.4 1.9e-09 37.6 0.4 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases ADH_N PF08240.12 KIK55235.1 - 4.2e-07 29.8 0.0 8.7e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain gag-asp_proteas PF13975.6 KIK55238.1 - 6.6e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK55238.1 - 0.00028 21.5 0.0 0.00044 20.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KIK55238.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease ADH_N PF08240.12 KIK55242.1 - 8.9e-06 25.6 0.1 7.5e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_cc PF11790.8 KIK55243.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core NodA PF02474.15 KIK55243.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein A (NodA) Pro_isomerase PF00160.21 KIK55244.1 - 5.1e-42 143.8 0.2 2.3e-40 138.4 0.0 2.4 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KIK55244.1 - 0.081 13.3 0.0 0.081 13.3 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4604) zf-C2H2_jaz PF12171.8 KIK55245.1 - 0.032 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK55245.1 - 0.16 12.9 0.1 0.16 12.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK55245.1 - 0.47 11.0 0.2 0.47 11.0 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type MKT1_C PF12246.8 KIK55247.1 - 9.7e-60 201.8 0.0 1.2e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Mid2 PF04478.12 KIK55250.1 - 0.0023 17.8 0.1 0.0035 17.2 0.1 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KIK55250.1 - 0.003 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Amnionless PF14828.6 KIK55250.1 - 0.0088 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 KIK55250.1 - 0.0093 15.4 0.3 0.023 14.1 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.16 KIK55250.1 - 0.025 13.3 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 KIK55250.1 - 0.031 13.9 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SPX PF03105.19 KIK55250.1 - 1.6 8.5 6.2 2 8.2 6.2 1.2 1 0 0 1 1 1 0 SPX domain Aegerolysin PF06355.13 KIK55251.1 - 5.3e-06 26.5 0.2 1.5e-05 25.1 0.2 1.7 1 1 0 1 1 1 1 Aegerolysin Aegerolysin PF06355.13 KIK55252.1 - 6.7e-08 32.7 0.2 1.6e-07 31.5 0.2 1.6 1 1 0 1 1 1 1 Aegerolysin TMEM154 PF15102.6 KIK55253.1 - 0.00024 21.0 0.5 0.00024 21.0 0.5 1.7 2 0 0 2 2 2 1 TMEM154 protein family Mid2 PF04478.12 KIK55253.1 - 0.005 16.7 0.8 0.0085 15.9 0.1 1.7 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor DUF4448 PF14610.6 KIK55253.1 - 0.006 16.4 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 KIK55253.1 - 0.024 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.20 KIK55253.1 - 0.026 14.4 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Hid1 PF12722.7 KIK55253.1 - 0.33 9.0 1.1 0.43 8.7 1.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 KIK55253.1 - 4.4 5.8 5.1 4.5 5.7 5.1 1.2 1 0 0 1 1 1 0 Macoilin family Thioredoxin PF00085.20 KIK55254.1 - 1.7e-16 60.0 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIK55254.1 - 3.9e-05 23.9 0.1 0.11 12.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KIK55254.1 - 0.00012 22.2 0.2 0.00023 21.3 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KIK55254.1 - 0.0043 17.5 0.2 0.012 16.1 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KIK55254.1 - 0.0085 15.9 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KIK55254.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin adh_short PF00106.25 KIK55256.1 - 1e-23 83.8 0.0 5.8e-22 78.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK55256.1 - 3.4e-13 49.7 0.0 1.1e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK55256.1 - 8.7e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK55256.1 - 0.00029 21.1 0.1 0.00062 20.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KIK55256.1 - 0.0025 17.0 0.2 0.0036 16.5 0.2 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK55256.1 - 0.0026 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK55256.1 - 0.0046 16.4 0.1 0.0067 15.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIK55256.1 - 0.031 13.7 0.1 0.096 12.0 0.1 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KIK55256.1 - 0.032 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIK55256.1 - 0.052 12.7 0.2 0.074 12.2 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK55256.1 - 0.083 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.20 KIK55256.1 - 0.093 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KIK55257.1 - 6.2e-33 113.9 0.0 4.2e-28 98.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK55257.1 - 2.4e-21 76.4 0.0 1.2e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK55257.1 - 1.2e-08 35.0 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK55257.1 - 2.9e-05 24.3 0.2 6.3e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIK55257.1 - 0.00011 21.7 0.3 0.00018 21.1 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK55257.1 - 0.00046 19.7 0.1 0.00067 19.1 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK55257.1 - 0.0026 17.0 0.1 0.0037 16.5 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein QRPTase_C PF01729.19 KIK55257.1 - 0.0042 16.9 0.1 0.0066 16.2 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1776 PF08643.10 KIK55257.1 - 0.0047 16.3 0.3 0.05 13.0 0.3 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KIK55257.1 - 0.0076 15.4 0.2 0.013 14.6 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KIK55257.1 - 0.011 15.8 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KIK55257.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KIK55257.1 - 0.042 13.4 0.2 0.067 12.7 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.17 KIK55257.1 - 0.064 13.8 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TIR-like PF10137.9 KIK55257.1 - 0.1 12.5 0.3 4.7 7.2 0.2 2.2 1 1 1 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain SMC_hinge PF06470.13 KIK55257.1 - 0.16 12.3 0.2 0.36 11.1 0.1 1.6 2 0 0 2 2 1 0 SMC proteins Flexible Hinge Domain adh_short PF00106.25 KIK55258.1 - 4.2e-30 104.7 0.0 5.6e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK55258.1 - 5.6e-20 71.9 0.0 4.7e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK55258.1 - 3.6e-07 30.3 0.1 5.5e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK55258.1 - 0.00034 20.2 0.1 0.00044 19.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK55258.1 - 0.00054 20.2 0.2 0.00096 19.4 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KIK55258.1 - 0.0049 16.1 0.3 0.0094 15.1 0.1 1.6 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK55258.1 - 0.0056 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK55258.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 KIK55258.1 - 0.044 13.2 0.1 0.62 9.4 0.1 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KIK55258.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein QRPTase_C PF01729.19 KIK55258.1 - 0.09 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NmrA PF05368.13 KIK55258.1 - 0.099 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family RcsD_ABL PF16359.5 KIK55258.1 - 0.11 12.7 0.1 0.26 11.4 0.1 1.6 2 0 0 2 2 2 0 RcsD-ABL domain ApbA PF02558.16 KIK55258.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KIK55258.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KDZ PF18758.1 KIK55265.1 - 1.8e-05 24.5 0.6 2.4e-05 24.1 0.6 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase adh_short PF00106.25 KIK55268.1 - 0.00026 20.5 0.0 0.00033 20.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK55268.1 - 0.0017 18.0 0.0 0.0019 17.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK55269.1 - 1.3e-21 77.0 0.4 1.6e-21 76.7 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK55269.1 - 1.1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK55269.1 - 3.8e-05 23.7 0.1 4.6e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK55269.1 - 0.00044 20.5 0.1 0.00062 20.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIK55269.1 - 0.00088 18.8 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIK55269.1 - 0.0029 16.8 0.1 0.0029 16.8 0.1 1.4 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK55269.1 - 0.0035 16.8 0.1 0.0052 16.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK55269.1 - 0.0055 15.9 0.4 0.0071 15.5 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KIK55269.1 - 0.01 15.8 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 KIK55269.1 - 0.016 15.3 0.1 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KIK55269.1 - 0.052 13.1 0.2 0.066 12.8 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Peptidase_M6 PF05547.11 KIK55269.1 - 0.091 11.1 0.0 0.095 11.0 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 GATA PF00320.27 KIK55270.1 - 4.3e-24 83.8 26.4 8.2e-14 50.9 5.8 3.3 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIK55270.1 - 0.00075 19.0 1.1 0.085 12.4 0.0 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding NMD3 PF04981.13 KIK55270.1 - 0.0047 16.4 0.7 0.059 12.8 0.1 2.1 2 0 0 2 2 2 1 NMD3 family DZR PF12773.7 KIK55270.1 - 0.015 15.4 7.8 0.46 10.6 0.4 2.9 2 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KIK55270.1 - 0.37 10.7 7.6 3 7.8 0.8 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CoatB PF10389.9 KIK55272.1 - 0.002 17.9 1.3 0.0042 16.9 1.3 1.5 1 0 0 1 1 1 1 Bacteriophage coat protein B SKG6 PF08693.10 KIK55272.1 - 0.0026 17.1 2.5 0.0052 16.2 2.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.16 KIK55272.1 - 0.0047 15.7 0.0 0.0068 15.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK55272.1 - 0.078 13.9 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GATA PF00320.27 KIK55273.1 - 3.4e-13 48.9 2.0 6e-13 48.2 2.0 1.4 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.27 KIK55274.1 - 8.7e-11 41.3 1.4 1.5e-10 40.5 1.4 1.4 1 0 0 1 1 1 1 GATA zinc finger UQ_con PF00179.26 KIK55277.1 - 2.5e-18 66.1 0.0 3.9e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GMC_oxred_N PF00732.19 KIK55278.1 - 8.9e-37 127.1 0.0 1.3e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK55278.1 - 1.7e-24 86.9 0.1 7.9e-24 84.8 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase F-box-like PF12937.7 KIK55279.1 - 1.1e-06 28.5 0.5 3.7e-06 26.7 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK55279.1 - 0.007 16.8 0.7 61 4.2 0.1 4.4 2 2 3 5 5 5 1 Leucine Rich repeats (2 copies) FTR1 PF03239.14 KIK55280.1 - 7.2e-65 219.2 4.3 8.5e-65 218.9 4.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4131 PF13567.6 KIK55280.1 - 0.0033 17.1 2.0 0.098 12.3 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) DUF3180 PF11377.8 KIK55280.1 - 1.3 9.2 9.6 0.91 9.7 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Cu-oxidase_2 PF07731.14 KIK55281.1 - 7.8e-38 129.3 2.8 5e-34 117.0 0.1 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KIK55281.1 - 6.7e-36 123.8 0.1 4.9e-34 117.8 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK55281.1 - 1.5e-30 105.6 1.4 3.9e-29 101.1 0.4 3.4 4 0 0 4 4 4 1 Multicopper oxidase Erythro_esteras PF05139.14 KIK55282.1 - 0.044 13.6 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Erythromycin esterase BTB PF00651.31 KIK55283.1 - 0.0002 21.5 0.0 0.0005 20.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ant_C PF05586.11 KIK55283.1 - 0.09 13.4 0.0 5.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Anthrax receptor C-terminus region Ank_2 PF12796.7 KIK55284.1 - 2.2e-34 117.9 21.6 3.6e-11 43.5 1.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK55284.1 - 2.3e-29 101.4 4.4 1e-08 35.5 0.0 5.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK55284.1 - 4.5e-22 75.8 9.7 0.036 14.6 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KIK55284.1 - 5e-22 77.3 18.3 0.0052 17.2 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KIK55284.1 - 2.3e-13 50.1 8.3 0.00047 20.4 0.1 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) TraB PF01963.17 KIK55284.1 - 0.13 12.2 0.7 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 TraB family Ank_4 PF13637.6 KIK55285.1 - 7.5e-25 87.0 6.5 6.4e-10 39.4 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK55285.1 - 1.6e-22 79.8 4.4 7.2e-13 48.9 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK55285.1 - 1.9e-14 53.3 9.5 0.0018 18.7 0.3 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KIK55285.1 - 1.6e-13 49.4 2.1 0.0083 16.6 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KIK55285.1 - 5e-08 33.1 1.2 0.0013 19.0 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KIK55285.1 - 0.089 12.7 0.9 23 5.0 0.0 3.2 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain YajC PF02699.15 KIK55285.1 - 0.31 10.9 2.7 49 3.9 0.1 3.6 1 1 3 4 4 4 0 Preprotein translocase subunit CD24 PF14984.6 KIK55285.1 - 3.1 8.1 8.8 74 3.7 0.1 4.0 4 0 0 4 4 4 0 CD24 protein NACHT PF05729.12 KIK55286.1 - 1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KIK55286.1 - 0.00012 22.1 0.0 0.0015 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK55286.1 - 0.0044 16.2 0.0 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KIK55286.1 - 0.0067 16.8 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK55286.1 - 0.0084 16.4 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KIK55286.1 - 0.014 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AhpC-TSA PF00578.21 KIK55286.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family PIF1 PF05970.14 KIK55286.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 KIK55286.1 - 0.062 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KIK55286.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KIK55286.1 - 0.081 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KIK55286.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family EpCAM_N PF18635.1 KIK55289.1 - 0.034 14.3 0.5 0.15 12.3 0.5 2.1 1 0 0 1 1 1 0 Epithelial cell adhesion molecule N-terminal domain RVT_2 PF07727.14 KIK55290.1 - 2.4e-13 50.3 0.0 1.1e-10 41.5 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_inhib PF16857.5 KIK55290.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase inhibitor zf-RRPl_C4 PF17026.5 KIK55293.1 - 0.24 11.5 2.4 0.6 10.2 2.4 1.8 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type OstA PF03968.14 KIK55294.1 - 0.089 13.0 6.0 0.27 11.5 5.2 1.8 1 1 1 2 2 2 0 OstA-like protein DUF3540 PF12059.8 KIK55294.1 - 0.1 12.4 7.9 0.8 9.5 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) TPKR_C2 PF16920.5 KIK55294.1 - 0.23 11.6 5.0 13 6.0 0.2 3.5 1 1 2 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain LptC PF06835.13 KIK55294.1 - 1.3 8.6 7.3 17 4.9 2.2 2.3 1 1 0 2 2 2 0 Lipopolysaccharide-assembly, LptC-related PARM PF17061.5 KIK55294.1 - 2 8.5 7.9 2.1 8.4 7.9 1.0 1 0 0 1 1 1 0 PARM MKT1_N PF12247.8 KIK55294.1 - 4.1 7.8 5.8 2.1e+02 2.3 5.8 2.3 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Big_2 PF02368.18 KIK55295.1 - 0.0041 17.0 0.1 0.0093 15.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 2) DUF1905 PF08922.11 KIK55295.1 - 0.031 14.3 0.3 0.065 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Orf78 PF06024.12 KIK55295.1 - 0.087 13.1 1.1 0.19 12.0 0.0 2.0 2 1 0 2 2 2 0 Orf78 (ac78) DUF1995 PF09353.10 KIK55295.1 - 0.099 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) Prok-RING_1 PF14446.6 KIK55298.1 - 0.41 10.6 4.7 0.092 12.7 1.0 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KIK55298.1 - 1.8 8.5 17.5 0.052 13.4 2.1 3.2 4 0 0 4 4 4 0 PHD-finger A2L_zn_ribbon PF08792.10 KIK55298.1 - 8.4 6.2 8.5 10 6.0 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain CobU PF02283.16 KIK55302.1 - 0.11 12.1 1.4 0.64 9.6 0.1 2.4 3 0 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4434 PF14488.6 KIK55302.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) EVI2A PF05399.11 KIK55303.1 - 0.0078 15.8 0.2 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Mltc_N PF11873.8 KIK55303.1 - 0.015 15.1 0.2 0.024 14.4 0.2 1.3 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain DUF4939 PF16297.5 KIK55303.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) iPGM_N PF06415.13 KIK55304.1 - 2.6e-77 259.1 0.0 4.2e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KIK55304.1 - 2.4e-73 246.6 1.5 2.8e-73 246.4 1.5 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KIK55304.1 - 0.00037 20.0 0.0 0.0016 17.9 0.0 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KIK55304.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KIK55304.1 - 0.0024 16.9 1.1 0.0096 14.9 0.3 2.0 2 0 0 2 2 2 1 Alkaline phosphatase PglZ PF08665.12 KIK55304.1 - 0.0039 17.3 0.0 0.009 16.1 0.0 1.6 2 0 0 2 2 2 1 PglZ domain Actin PF00022.19 KIK55305.1 - 1.4e-139 465.2 0.0 8.4e-139 462.7 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KIK55305.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DIOX_N PF14226.6 KIK55307.1 - 1.1e-15 58.4 0.0 1.9e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK55307.1 - 1.3e-12 48.1 0.0 2.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Gp_dh_C PF02800.20 KIK55308.1 - 5.2e-69 230.9 0.0 8e-69 230.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KIK55308.1 - 1.5e-38 131.1 0.2 4.3e-38 129.7 0.2 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KIK55308.1 - 0.0086 16.2 0.1 0.056 13.6 0.0 2.3 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KIK55308.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.7 KIK55309.1 - 0.0012 18.7 1.3 0.0034 17.2 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK55309.1 - 0.0038 17.1 0.4 0.018 14.9 0.4 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK55310.1 - 0.0009 19.1 2.4 0.0025 17.7 2.4 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK55311.1 - 0.00018 21.3 0.7 0.00018 21.3 0.7 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK55311.1 - 0.33 10.9 5.2 0.32 10.9 0.8 3.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK55312.1 - 4.4e-05 23.3 3.1 6.8e-05 22.7 1.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK55312.1 - 0.0017 18.2 5.9 0.009 15.9 0.5 3.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KIK55313.1 - 0.0011 18.8 0.4 0.0038 17.1 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK55313.1 - 0.022 14.6 0.7 0.15 12.0 0.1 2.8 3 0 0 3 3 3 0 F-box domain LRR_6 PF13516.6 KIK55313.1 - 1.4 9.2 7.4 35 4.8 0.0 5.1 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.7 KIK55314.1 - 0.0022 17.9 1.4 0.0077 16.1 1.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK55314.1 - 0.03 14.2 0.6 0.03 14.2 0.6 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK55315.1 - 0.00011 22.0 0.2 0.00043 20.1 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK55315.1 - 0.002 17.9 1.6 0.011 15.5 0.3 2.8 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 KIK55316.1 - 1.6e-55 188.7 0.0 2.2e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5109 PF17134.4 KIK55316.1 - 0.0082 16.0 0.1 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5109) p450 PF00067.22 KIK55317.1 - 2.6e-48 164.9 0.0 6.9e-48 163.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Glyco_hydro_88 PF07470.13 KIK55319.1 - 2e-17 63.3 0.1 2.6e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 IlvC PF01450.19 KIK55320.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ank_2 PF12796.7 KIK55321.1 - 7.6e-08 32.8 0.9 4.1e-05 24.1 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK55321.1 - 0.0019 18.5 0.1 0.27 11.6 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK55321.1 - 0.007 16.8 0.1 11 7.0 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KIK55321.1 - 0.024 15.2 0.0 1.1 10.0 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) NACHT PF05729.12 KIK55323.1 - 0.00024 21.1 0.0 0.00024 21.1 0.0 1.1 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK55323.1 - 0.00051 20.4 0.0 0.00067 20.0 0.0 1.3 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KIK55323.1 - 0.0023 18.4 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.17 KIK55323.1 - 0.013 14.6 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK55323.1 - 0.016 15.6 0.1 0.017 15.5 0.1 1.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KIK55323.1 - 0.026 14.3 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 KIK55323.1 - 0.047 13.4 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIK55323.1 - 0.048 13.7 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KIK55323.1 - 0.049 13.9 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK55323.1 - 0.051 13.3 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK55323.1 - 0.077 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK55323.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 KIK55323.1 - 0.088 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KIK55323.1 - 0.13 12.1 0.1 0.18 11.5 0.1 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KIK55323.1 - 0.18 12.3 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KIK55323.1 - 0.18 12.3 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Tim44 PF04280.15 KIK55325.1 - 2.4e-34 118.5 1.3 3.1e-34 118.2 0.2 1.8 2 0 0 2 2 2 1 Tim44-like domain DUF1778 PF08681.11 KIK55325.1 - 0.016 15.1 5.7 2.9 7.9 1.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1778) CENP-O PF09496.10 KIK55325.1 - 0.041 13.9 4.3 0.11 12.4 1.2 2.4 2 1 0 2 2 2 0 Cenp-O kinetochore centromere component MapZ_EC1 PF18041.1 KIK55325.1 - 0.048 13.9 2.3 0.57 10.4 0.6 2.9 3 0 0 3 3 3 0 MapZ extracellular domain 1 HTH_12 PF08461.10 KIK55325.1 - 0.048 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Secretin_N PF03958.17 KIK55325.1 - 0.1 13.0 0.6 0.43 11.0 0.6 2.1 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Ribosomal_S20p PF01649.18 KIK55325.1 - 0.25 12.0 0.2 0.25 12.0 0.2 2.5 1 1 1 2 2 2 0 Ribosomal protein S20 Seryl_tRNA_N PF02403.22 KIK55325.1 - 0.27 11.5 8.5 0.16 12.2 5.2 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 KIK55325.1 - 1.6 9.4 7.4 0.75 10.5 2.5 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DMPK_coil PF08826.10 KIK55325.1 - 1.8 8.7 7.5 0.15 12.2 0.8 2.6 2 1 1 3 3 3 0 DMPK coiled coil domain like dsrm PF00035.26 KIK55326.1 - 4.4e-06 27.3 0.0 7.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif zf-met PF12874.7 KIK55327.1 - 0.00089 19.6 0.4 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIK55327.1 - 0.002 18.5 7.3 0.042 14.3 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK55327.1 - 0.0037 18.0 5.9 0.19 12.6 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK55327.1 - 0.022 15.0 2.0 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FpoO PF10621.9 KIK55327.1 - 0.026 14.8 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO zf-H2C2_2 PF13465.6 KIK55327.1 - 0.088 13.3 1.3 0.088 13.3 1.3 2.4 2 1 0 2 2 2 0 Zinc-finger double domain Gly_transf_sug PF04488.15 KIK55329.1 - 5.6e-07 30.1 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK55329.1 - 4e-05 23.1 0.3 6.5e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TPR_10 PF13374.6 KIK55331.1 - 4.1e-94 306.3 17.0 6.9e-12 44.8 0.0 8.0 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK55331.1 - 1.9e-84 278.0 34.3 6.1e-16 58.5 0.8 6.3 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK55331.1 - 1.1e-21 77.7 14.5 8.5e-10 38.5 5.2 3.3 1 1 2 3 3 3 3 MalT-like TPR region TPR_17 PF13431.6 KIK55331.1 - 4.2e-21 73.8 6.2 0.21 12.1 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55331.1 - 1.1e-20 72.5 22.2 0.091 12.6 0.1 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 KIK55331.1 - 2.5e-20 70.9 25.1 0.018 15.2 0.1 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KIK55331.1 - 2.9e-19 67.6 16.1 0.4 10.8 0.1 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 KIK55331.1 - 5.9e-18 63.5 20.7 0.02 15.0 0.0 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_4 PF07721.14 KIK55331.1 - 6e-17 60.5 0.0 0.15 12.8 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK55331.1 - 7.2e-12 45.7 0.4 1.8 9.1 0.0 6.8 1 1 6 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK55331.1 - 3.7e-08 33.9 0.0 5.4 7.8 0.0 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.9 KIK55331.1 - 4.3e-06 26.6 13.1 0.079 12.7 0.1 5.2 2 2 5 7 7 7 4 26S proteasome subunit RPN7 TPR_14 PF13428.6 KIK55331.1 - 0.014 16.2 9.4 68 4.7 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 KIK55331.1 - 0.028 14.7 25.1 27 5.3 0.1 8.3 8 1 0 8 8 8 0 PPR repeat DUF1897 PF09005.10 KIK55331.1 - 0.063 12.8 10.1 11 5.6 0.0 6.6 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) TPR_3 PF07720.12 KIK55331.1 - 0.14 12.2 15.0 3.6 7.7 0.1 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat MCPVI PF02993.14 KIK55331.1 - 0.21 11.4 2.6 1.5e+02 2.1 0.0 4.5 1 1 4 6 6 6 0 Minor capsid protein VI TPR_11 PF13414.6 KIK55331.1 - 0.35 10.6 10.2 44 3.9 0.0 6.5 8 0 0 8 8 8 0 TPR repeat SSI PF00720.17 KIK55331.1 - 1.4 8.9 3.1 11 6.0 0.1 3.4 1 1 0 4 4 4 0 Subtilisin inhibitor-like Cation_ATPase_C PF00689.21 KIK55333.1 - 2.1e-43 148.2 10.3 2.1e-43 148.2 10.3 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIK55333.1 - 1.5e-38 132.1 0.4 1.5e-38 132.1 0.4 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIK55333.1 - 1.1e-15 57.4 0.0 2.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK55333.1 - 6.1e-13 49.5 0.3 2.7e-12 47.4 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK55333.1 - 4.5e-07 29.5 0.0 1.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK55333.1 - 0.00037 20.3 0.4 0.015 15.1 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Insulin_TMD PF17870.1 KIK55333.1 - 1.6 8.8 4.0 15 5.8 1.6 2.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment FXR_C3 PF16097.5 KIK55335.1 - 0.023 15.4 2.4 0.042 14.5 2.4 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 Arf PF00025.21 KIK55338.1 - 0.02 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 KIK55338.1 - 0.031 14.6 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KIK55338.1 - 0.076 13.2 0.2 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK55338.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK55338.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK55338.1 - 0.15 12.0 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KIK55338.1 - 0.19 11.3 0.2 2.1 7.9 0.1 2.3 1 1 2 3 3 3 0 AAA domain OCRE PF17780.1 KIK55339.1 - 0.19 11.8 3.4 8.5 6.5 0.7 2.4 2 0 0 2 2 2 0 OCRE domain Adap_comp_sub PF00928.21 KIK55340.1 - 4.3e-91 305.0 0.1 8e-91 304.1 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK55340.1 - 5.1e-06 26.5 0.2 8.8e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KIK55340.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Lipase_3 PF01764.25 KIK55341.1 - 1.7e-16 60.4 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KIK55341.1 - 0.049 12.9 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Spt4 PF06093.13 KIK55344.1 - 1.2e-29 102.2 0.1 1.5e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Mito_carr PF00153.27 KIK55346.1 - 1.6e-44 149.8 1.6 1.3e-17 63.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein L_HMGIC_fpl PF10242.9 KIK55348.1 - 0.019 15.2 0.2 0.025 14.8 0.2 1.1 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein WSC PF01822.19 KIK55349.1 - 2.4e-39 133.4 32.2 3.4e-16 59.2 3.4 5.9 4 1 0 5 5 5 3 WSC domain DUF262 PF03235.14 KIK55350.1 - 3.4e-16 60.1 0.4 9.2e-16 58.7 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 Sugar_tr PF00083.24 KIK55351.1 - 4.8e-105 352.0 19.1 5.6e-105 351.8 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK55351.1 - 2.1e-24 86.1 22.7 1.5e-21 76.8 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KIK55351.1 - 2 7.3 20.5 0.3 10.0 10.1 2.6 2 1 0 2 2 2 0 PUCC protein DUF1673 PF07895.11 KIK55351.1 - 3.7 7.2 8.0 8.3 6.1 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Abhydrolase_1 PF00561.20 KIK55352.1 - 3.5e-46 157.9 0.0 4.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK55352.1 - 0.00058 20.5 3.4 0.001 19.7 3.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M24 PF00557.24 KIK55353.1 - 1.9e-57 194.3 0.0 2.5e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIK55353.1 - 3.1e-40 136.7 0.0 5.7e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3835 PF12927.7 KIK55354.1 - 0.0076 17.1 21.0 0.033 15.0 0.2 4.9 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) DUF262 PF03235.14 KIK55355.1 - 1.9e-17 64.2 0.2 4.3e-17 63.0 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF262 ALO PF04030.14 KIK55357.1 - 6e-08 32.8 2.0 1.1e-07 31.9 2.0 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK55357.1 - 9.8e-08 31.8 0.1 3e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Chol_subst-bind PF09129.11 KIK55357.1 - 0.0056 15.7 5.6 0.015 14.2 1.1 2.7 2 1 0 2 2 2 2 Cholesterol oxidase, substrate-binding Nop PF01798.18 KIK55358.1 - 2.7e-83 279.0 0.0 2.7e-83 279.0 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIK55358.1 - 2.3e-20 72.7 0.9 2.3e-20 72.7 0.9 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain FeoB_Cyto PF17910.1 KIK55359.1 - 0.02 15.4 0.2 0.059 13.9 0.2 1.7 1 0 0 1 1 1 0 FeoB cytosolic helical domain Polyoma_coat2 PF00761.20 KIK55359.1 - 0.023 14.4 0.2 0.042 13.6 0.2 1.5 1 0 0 1 1 1 0 Polyomavirus coat protein GerPC PF10737.9 KIK55359.1 - 0.13 12.3 0.7 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Spore germination protein GerPC RPW8 PF05659.11 KIK55359.1 - 0.99 9.1 5.3 0.16 11.7 0.3 2.2 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DASH_Dam1 PF08653.10 KIK55359.1 - 1.6 8.6 3.7 10 6.0 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 KIK55359.1 - 9.4 6.3 8.3 4.3 7.4 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AhpC-TSA PF00578.21 KIK55360.1 - 3.1e-08 33.6 0.0 3.7e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1087 PF06465.13 KIK55360.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) YL1 PF05764.13 KIK55361.1 - 0.61 10.2 18.3 0.26 11.4 13.2 2.0 1 1 1 2 2 2 0 YL1 nuclear protein Peptidase_S64 PF08192.11 KIK55361.1 - 3.3 6.1 6.2 3.8 5.9 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 KIK55361.1 - 4 5.6 10.8 0.57 8.4 7.0 1.5 2 0 0 2 2 2 0 CDC45-like protein DnaJ PF00226.31 KIK55363.1 - 1.5e-19 69.9 0.3 1.3e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain ANTH PF07651.16 KIK55363.1 - 0.0092 15.0 2.3 0.016 14.2 2.3 1.3 1 0 0 1 1 1 1 ANTH domain Beta-lactamase2 PF13354.6 KIK55363.1 - 0.074 12.6 0.7 0.1 12.2 0.7 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family DUF1217 PF06748.12 KIK55363.1 - 0.11 12.6 1.4 0.16 12.0 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1217) RR_TM4-6 PF06459.12 KIK55363.1 - 0.18 11.6 7.0 0.24 11.2 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4449 PF14613.6 KIK55363.1 - 0.26 11.4 9.2 0.072 13.2 5.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Atg14 PF10186.9 KIK55363.1 - 0.44 9.6 10.4 0.68 9.0 10.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YtxH PF12732.7 KIK55363.1 - 4.5 7.9 5.6 29 5.3 5.6 2.3 1 1 0 1 1 1 0 YtxH-like protein Presenilin PF01080.17 KIK55363.1 - 5.7 5.6 6.0 6.5 5.4 6.0 1.2 1 0 0 1 1 1 0 Presenilin DUF2514 PF10721.9 KIK55363.1 - 6.6 6.7 13.4 0.55 10.3 8.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Caldesmon PF02029.15 KIK55363.1 - 7.9 5.1 25.5 13 4.4 25.5 1.5 1 1 0 1 1 1 0 Caldesmon RSB_motif PF16294.5 KIK55363.1 - 8.5 6.7 17.7 0.36 11.1 11.0 2.1 2 1 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif tRNA_int_end_N2 PF12928.7 KIK55364.1 - 2.5e-20 72.4 0.0 4.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KIK55364.1 - 0.0052 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain AA_permease_2 PF13520.6 KIK55367.1 - 1.3e-43 149.4 51.6 1.9e-43 148.9 51.6 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.27 KIK55367.1 - 4.9e-33 114.3 0.0 4.9e-33 114.3 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AA_permease PF00324.21 KIK55367.1 - 2.2e-21 76.0 41.2 2.9e-21 75.6 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease IF-2 PF11987.8 KIK55367.1 - 1.8e-19 69.8 0.0 4.5e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KIK55367.1 - 1.9e-15 57.0 6.4 3.7e-10 40.1 0.1 4.0 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK55367.1 - 3e-06 27.3 0.1 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KIK55367.1 - 0.00014 21.7 0.1 0.00036 20.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KIK55367.1 - 0.00023 21.4 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIK55367.1 - 0.034 13.9 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KIK55367.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 Ras family Arf PF00025.21 KIK55368.1 - 1.2e-69 233.2 0.7 1.4e-69 233.0 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK55368.1 - 6.5e-13 48.6 1.2 1.1e-07 31.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIK55368.1 - 8.2e-11 42.2 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK55368.1 - 1.9e-10 40.5 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIK55368.1 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KIK55368.1 - 1.9e-09 37.3 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KIK55368.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KIK55368.1 - 0.0037 16.9 0.1 0.043 13.4 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KIK55368.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CMAS PF02353.20 KIK55369.1 - 8.1e-57 192.6 0.0 1.2e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK55369.1 - 1.1e-08 35.7 0.0 2.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK55369.1 - 8.3e-07 29.6 0.0 1.9e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK55369.1 - 3.9e-05 23.5 0.0 7.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK55369.1 - 0.0073 16.1 0.0 0.043 13.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 KIK55369.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KIK55369.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KIK55369.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GCD14 PF08704.10 KIK55369.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 KIK55369.1 - 0.16 11.5 0.0 0.38 10.2 0.0 1.6 1 1 1 2 2 2 0 Histone methylation protein DOT1 Kinesin PF00225.23 KIK55370.1 - 2.4e-108 362.0 0.0 4e-108 361.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KIK55370.1 - 1.1e-39 136.4 5.3 1.3e-30 106.9 2.4 2.7 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 KIK55370.1 - 5.2e-38 131.1 0.0 1.5e-37 129.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KIK55370.1 - 7e-21 74.7 0.0 1.7e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KIK55370.1 - 3e-10 40.5 0.0 1.2e-09 38.7 0.0 2.0 2 0 0 2 2 2 1 PH domain FHA PF00498.26 KIK55370.1 - 8.6e-07 29.2 0.0 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KIK55370.1 - 4.8e-06 26.9 0.7 1.8e-05 25.1 0.7 2.0 1 0 0 1 1 1 1 Kinesin protein 1B EAP30 PF04157.16 KIK55370.1 - 0.046 13.0 1.5 0.095 12.0 0.5 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family EMP24_GP25L PF01105.24 KIK55370.1 - 1.6 8.7 3.3 2.7 7.9 1.0 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RNA_pol_Rpb1_R PF05001.13 KIK55371.1 - 7.1 7.2 8.6 22 5.6 0.8 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat DNA_methylase PF00145.17 KIK55374.1 - 2.1e-12 47.1 0.0 3.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 KIK55374.1 - 0.00026 20.6 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KIK55374.1 - 0.04 14.6 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIK55374.1 - 0.085 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 KIK55375.1 - 8e-07 28.7 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Coagulin PF02035.15 KIK55377.1 - 0.0063 16.4 0.1 0.0072 16.2 0.1 1.0 1 0 0 1 1 1 1 Coagulin Bac_rhamnosid_N PF08531.10 KIK55378.1 - 6.7e-06 26.0 2.7 0.0011 18.9 0.1 3.6 3 1 0 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 KIK55378.1 - 0.09 12.7 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain F-box-like PF12937.7 KIK55379.1 - 1.1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Polyoma_agno PF01736.16 KIK55379.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus agnoprotein Ferlin_C PF16165.5 KIK55380.1 - 0.12 12.3 0.6 0.17 11.8 0.6 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Mito_carr PF00153.27 KIK55381.1 - 4.9e-64 212.3 2.1 5.9e-23 80.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK55381.1 - 4.3 6.4 6.9 6.3 5.9 0.1 3.4 2 2 2 4 4 4 0 Gammaproteobacterial serine protease SOG2 PF10428.9 KIK55384.1 - 0.16 11.2 6.4 0.17 11.0 6.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein G-gamma PF00631.22 KIK55384.1 - 0.22 11.5 1.0 4 7.5 1.6 2.1 2 0 0 2 2 2 0 GGL domain Acyl-CoA_dh_1 PF00441.24 KIK55385.1 - 3e-28 98.9 0.3 4.6e-28 98.3 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK55385.1 - 2.6e-17 62.8 0.3 4.7e-17 62.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIK55385.1 - 7.7e-16 58.0 0.1 3e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIK55385.1 - 6.3e-14 52.6 0.0 1.9e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK55385.1 - 1.8e-05 25.1 0.0 3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoaE PF01121.20 KIK55385.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase OHCU_decarbox PF09349.10 KIK55386.1 - 2.5e-25 89.7 0.0 5.3e-25 88.7 0.0 1.5 1 1 0 1 1 1 1 OHCU decarboxylase TFIIA PF03153.13 KIK55387.1 - 0.49 10.3 11.2 0.6 10.0 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 KIK55388.1 - 1.1e-21 76.9 1.3 6.8e-13 48.8 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK55388.1 - 2.1e-19 69.3 0.6 5.9e-14 52.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK55388.1 - 1.6e-16 60.7 0.4 2.9e-16 59.8 0.3 1.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK55388.1 - 1.3e-15 57.1 4.0 1.1e-06 28.7 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK55388.1 - 1.2e-14 53.0 0.8 3.8e-07 29.9 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat GHMP_kinases_N PF00288.26 KIK55390.1 - 5.9e-11 42.4 1.1 1.6e-10 41.1 1.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain NFRKB_winged PF14465.6 KIK55390.1 - 0.19 12.0 0.9 0.35 11.1 0.1 1.8 2 0 0 2 2 2 0 NFRKB Winged Helix-like Forkhead PF00250.18 KIK55391.1 - 8.5e-09 35.6 0.0 9.3e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain zf-RING_UBOX PF13445.6 KIK55392.1 - 5.5e-08 32.7 6.3 5.5e-08 32.7 6.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK55392.1 - 6.4e-08 32.3 8.8 1.1e-07 31.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK55392.1 - 9.7e-08 32.2 9.7 1.7e-07 31.4 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIK55392.1 - 8.6e-07 29.0 9.8 1.8e-06 28.0 9.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KIK55392.1 - 1.8e-06 27.7 7.4 3.1e-06 27.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK55392.1 - 2.1e-06 27.6 8.7 3.6e-06 26.8 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK55392.1 - 1.3e-05 24.9 7.9 2.9e-05 23.8 7.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIK55392.1 - 1.4e-05 24.8 12.6 7e-05 22.6 12.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK55392.1 - 0.004 17.4 9.3 0.035 14.4 9.3 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIK55392.1 - 0.0042 16.9 4.7 0.0083 16.0 4.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.15 KIK55392.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain DUF1244 PF06844.11 KIK55392.1 - 0.046 13.9 0.6 0.1 12.8 0.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1244) zf-4CXXC_R1 PF10497.9 KIK55392.1 - 0.071 13.3 2.2 0.15 12.3 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Tmpp129 PF10272.9 KIK55392.1 - 0.09 12.1 2.4 0.14 11.4 2.4 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor CEBP_ZZ PF16366.5 KIK55392.1 - 0.11 12.7 7.1 44 4.4 7.1 2.3 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_4 PF14570.6 KIK55392.1 - 0.27 11.0 6.0 0.6 9.9 6.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KIK55392.1 - 0.31 11.2 8.1 1.2 9.4 8.1 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KIK55392.1 - 0.47 10.5 4.2 2.9 8.0 4.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 KIK55392.1 - 1.1 9.5 6.0 2.9 8.1 6.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-B_box PF00643.24 KIK55392.1 - 4.1 7.6 8.3 17 5.7 4.1 2.3 2 0 0 2 2 2 0 B-box zinc finger FANCL_C PF11793.8 KIK55392.1 - 6.5 7.0 8.5 22 5.3 8.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Helicase_C PF00271.31 KIK55393.1 - 5.9e-19 68.5 0.0 7.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIK55393.1 - 0.0078 15.4 0.0 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CAMSAP_CKK PF08683.11 KIK55393.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated SNF2_N PF00176.23 KIK55394.1 - 2.1e-27 95.8 0.0 3e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KIK55394.1 - 0.056 13.2 0.0 0.089 12.6 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase FcoT PF10862.8 KIK55395.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 FcoT-like thioesterase domain MRP-L20 PF12824.7 KIK55395.1 - 0.051 13.7 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 WD40 PF00400.32 KIK55397.1 - 0.00014 22.6 2.2 0.0033 18.2 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Prot_inhib_II PF02428.15 KIK55401.1 - 0.12 12.8 2.1 0.23 11.9 2.1 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family AAA_16 PF13191.6 KIK55402.1 - 7.8e-06 26.4 0.0 8.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK55402.1 - 4.3e-05 23.5 0.2 8.5e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KIK55402.1 - 0.0004 20.1 0.0 0.00043 20.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KIK55402.1 - 0.00049 19.6 0.0 0.00062 19.3 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein RNA_helicase PF00910.22 KIK55402.1 - 0.00081 19.8 0.0 0.0019 18.5 0.0 1.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KIK55402.1 - 0.0017 18.6 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK55402.1 - 0.0032 16.7 0.1 0.0036 16.5 0.1 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK55402.1 - 0.0045 17.5 0.1 0.0072 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK55402.1 - 0.009 16.5 0.1 0.012 16.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KIK55402.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.3 1 1 0 1 1 1 1 P-loop containing dynein motor region APS_kinase PF01583.20 KIK55402.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 KIK55402.1 - 0.022 14.0 0.1 0.034 13.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 KIK55402.1 - 0.025 14.3 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 KIK55402.1 - 0.052 13.5 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 KIK55402.1 - 0.053 13.6 0.1 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KIK55402.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 2 1 0 2 2 2 0 Thymidylate kinase AAA_33 PF13671.6 KIK55402.1 - 0.06 13.5 0.1 0.078 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK55402.1 - 0.062 13.0 0.1 0.15 11.8 0.1 1.7 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 KIK55402.1 - 0.066 13.5 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK55402.1 - 0.07 12.3 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA PF00004.29 KIK55402.1 - 0.094 13.1 0.1 0.13 12.7 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KIK55402.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Cytidylate_kin PF02224.18 KIK55402.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 Cytidylate kinase Sigma54_activat PF00158.26 KIK55402.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KIK55402.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 KIK55402.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 KIK55402.1 - 3.9 7.9 6.3 28 5.1 6.4 2.0 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK55406.1 - 1e-85 279.3 49.8 8.1e-09 36.0 0.1 11.9 11 1 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55406.1 - 1.6e-33 114.9 0.7 0.032 14.5 0.0 10.0 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK55406.1 - 1.5e-17 63.1 20.4 0.98 9.4 0.1 11.1 11 0 0 11 11 11 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK55406.1 - 1.1e-09 37.7 0.2 4.3 6.2 0.0 8.9 4 3 4 10 10 10 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK55406.1 - 4.6e-08 32.6 14.8 6.1 6.6 0.1 9.7 10 0 0 10 10 10 1 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KIK55406.1 - 1.5e-06 27.2 7.0 7.7 5.0 0.5 8.0 5 1 1 9 9 9 2 Nucleoporin Nup120/160 Ret2_MD PF18528.1 KIK55406.1 - 9.7e-06 25.9 0.0 8.2 6.9 0.0 7.5 2 2 9 11 11 11 1 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40_like PF17005.5 KIK55406.1 - 3.9e-05 23.1 0.0 5.3 6.3 0.0 5.8 5 3 3 8 8 8 1 WD40-like domain DUF4265 PF14085.6 KIK55406.1 - 0.0008 19.4 0.1 53 3.8 0.0 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4265) DUF4685 PF15737.5 KIK55406.1 - 0.008 16.6 0.0 49 4.4 0.0 4.6 4 2 2 6 6 6 0 Domain of unknown function (DUF4685) 5-FTHF_cyc-lig PF01812.20 KIK55406.1 - 0.21 11.4 0.1 1e+02 2.6 0.0 4.6 7 2 2 9 9 9 0 5-formyltetrahydrofolate cyclo-ligase family Frtz PF11768.8 KIK55406.1 - 0.25 9.6 0.0 29 2.8 0.0 4.0 5 2 2 7 7 7 0 WD repeat-containing and planar cell polarity effector protein Fritz UL42 PF17638.2 KIK55407.1 - 0.24 11.4 7.1 0.4 10.7 6.8 1.7 1 1 0 1 1 1 0 HCMV UL42 ODV-E18 PF10717.9 KIK55409.1 - 0.0027 17.5 0.2 0.0035 17.2 0.2 1.1 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF1980 PF09323.10 KIK55409.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3246 PF11596.8 KIK55410.1 - 0.036 13.5 3.3 0.079 12.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 KIK55410.1 - 0.82 10.1 12.1 0.15 12.4 2.8 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain NACHT PF05729.12 KIK55412.1 - 5.5e-06 26.4 0.0 7.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK55412.1 - 1.8e-05 25.2 0.0 2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIK55412.1 - 0.00069 19.4 0.0 0.00084 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK55412.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK55412.1 - 0.0018 17.5 0.0 0.0022 17.2 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK55412.1 - 0.0041 17.7 0.1 0.0064 17.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK55412.1 - 0.0064 16.8 0.0 0.0082 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK55412.1 - 0.0099 16.3 0.1 0.026 14.9 0.0 1.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KIK55412.1 - 0.018 15.6 0.0 0.023 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KIK55412.1 - 0.018 14.9 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_7 PF12775.7 KIK55412.1 - 0.045 13.3 0.0 0.057 12.9 0.0 1.3 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_26 PF13500.6 KIK55412.1 - 0.061 13.1 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK55412.1 - 0.072 12.5 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 KIK55412.1 - 0.077 13.4 0.5 0.17 12.3 0.5 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIK55412.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KIK55412.1 - 0.17 12.1 0.3 0.36 11.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK55412.1 - 1.7 9.1 3.9 1.1 9.8 0.3 1.9 1 1 1 2 2 2 0 AAA domain DUF4441 PF14536.6 KIK55413.1 - 0.055 13.7 4.1 0.12 12.6 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) WD40 PF00400.32 KIK55414.1 - 1.5e-11 44.6 0.6 7.7e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40_like PF17005.5 KIK55414.1 - 0.0028 17.0 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 WD40-like domain PD40 PF07676.12 KIK55414.1 - 0.0051 16.7 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat rOmpB PF12334.8 KIK55414.1 - 0.022 14.2 0.4 0.099 12.1 0.0 1.9 2 0 0 2 2 2 0 Rickettsia outer membrane protein B GTP_EFTU_D4 PF14578.6 KIK55414.1 - 0.055 13.4 0.6 0.15 12.0 0.5 1.7 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Transposase_21 PF02992.14 KIK55416.1 - 5.8e-05 22.4 0.0 6.7e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 DUF4781 PF16013.5 KIK55419.1 - 0.18 10.6 0.3 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) WD40 PF00400.32 KIK55420.1 - 2.5e-26 91.4 7.9 1.7e-09 38.1 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55420.1 - 2e-10 40.8 1.4 0.0097 16.2 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK55420.1 - 1.4e-08 34.8 0.1 2.9e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK55420.1 - 0.00011 22.1 0.5 1.7 8.6 0.0 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK55420.1 - 0.00012 21.5 0.0 0.033 13.5 0.0 3.1 3 1 0 3 3 3 1 WD40-like domain AAA_16 PF13191.6 KIK55420.1 - 0.0003 21.2 0.2 0.0018 18.7 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.6 KIK55420.1 - 0.004 17.5 0.1 0.059 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK55420.1 - 0.0043 17.0 0.6 0.047 13.6 0.0 2.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK55420.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK55420.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK55420.1 - 0.016 15.8 0.1 0.065 13.8 0.0 2.1 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 KIK55420.1 - 0.092 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Zein-binding PF04576.15 KIK55420.1 - 0.11 12.8 0.4 8.6 6.7 0.1 2.7 2 0 0 2 2 2 0 Zein-binding ABC_tran PF00005.27 KIK55420.1 - 0.14 12.7 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FliS PF02561.14 KIK55420.1 - 0.16 12.3 0.5 0.73 10.1 0.0 2.4 3 0 0 3 3 3 0 Flagellar protein FliS Spore_Cse60 PF10957.8 KIK55420.1 - 0.76 9.8 4.4 0.28 11.2 0.3 2.5 3 0 0 3 3 2 0 Sporulation protein Cse60 DUF87 PF01935.17 KIK55420.1 - 0.82 9.7 3.6 3.4 7.7 0.3 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain gag-asp_proteas PF13975.6 KIK55421.1 - 0.0001 22.8 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 KIK55421.1 - 0.00016 21.2 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 KIK55421.1 - 0.0035 17.9 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 KIK55422.1 - 0.032 14.5 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Transcrip_act PF04949.13 KIK55426.1 - 0.0021 18.0 1.6 0.0021 18.0 1.6 2.1 2 0 0 2 2 2 1 Transcriptional activator Csm1_N PF18504.1 KIK55426.1 - 0.04 14.3 19.4 0.8 10.1 4.3 3.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Peptidase_S49_N PF08496.10 KIK55426.1 - 0.083 12.9 0.2 0.083 12.9 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Fib_alpha PF08702.10 KIK55426.1 - 0.16 12.1 11.1 0.62 10.2 1.6 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 KIK55426.1 - 0.8 9.4 10.1 1.1 8.9 4.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF641 PF04859.12 KIK55426.1 - 1.3 9.4 14.6 6.4 7.1 4.2 3.8 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF327 PF03885.13 KIK55426.1 - 1.4 8.9 6.5 0.72 9.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Bacillus_HBL PF05791.11 KIK55426.1 - 1.5 8.7 5.1 2.8 7.7 1.0 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 KIK55426.1 - 1.5 7.6 21.1 0.096 11.5 9.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein CCDC74_C PF14917.6 KIK55426.1 - 2.1 8.9 10.3 1.8 9.1 0.6 3.0 3 0 0 3 3 3 0 Coiled coil protein 74, C terminal HMMR_N PF15905.5 KIK55426.1 - 2.2 7.7 20.6 0.43 10.0 12.8 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Med9 PF07544.13 KIK55426.1 - 4.3 7.5 11.7 1.9 8.6 0.2 4.1 3 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 LRS4 PF10422.9 KIK55426.1 - 4.9 6.7 13.1 11 5.5 13.1 1.6 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Sec2p PF06428.11 KIK55426.1 - 5 7.2 15.5 0.09 12.8 1.1 3.9 2 2 1 4 4 4 0 GDP/GTP exchange factor Sec2p Spc42p PF11544.8 KIK55426.1 - 8.2 6.5 7.4 7.8 6.6 1.2 3.4 2 2 0 2 2 2 0 Spindle pole body component Spc42p AAA_16 PF13191.6 KIK55427.1 - 4.4e-06 27.2 0.2 0.00018 21.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KIK55427.1 - 1.4e-05 24.5 1.0 0.011 15.0 0.0 2.8 2 1 1 3 3 3 1 NB-ARC domain AAA_30 PF13604.6 KIK55427.1 - 0.00072 19.3 0.1 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK55427.1 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK55427.1 - 0.0031 17.9 0.4 0.034 14.5 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KIK55427.1 - 0.0062 16.5 0.3 3.7 7.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK55427.1 - 0.0074 16.6 0.5 0.3 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIK55427.1 - 0.01 15.1 0.1 0.91 8.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KIK55427.1 - 0.014 15.9 4.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK55427.1 - 0.02 15.4 1.1 0.15 12.6 0.0 2.4 2 1 0 2 2 2 0 ABC transporter KTI12 PF08433.10 KIK55427.1 - 0.026 14.0 1.7 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SLATT_1 PF18181.1 KIK55427.1 - 0.026 14.5 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 AAA_18 PF13238.6 KIK55427.1 - 0.026 15.0 0.1 0.095 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain MazG PF03819.17 KIK55427.1 - 0.037 14.2 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 1 0 MazG nucleotide pyrophosphohydrolase domain MukF_M PF17192.4 KIK55427.1 - 0.041 13.6 1.3 0.28 10.9 0.1 2.6 1 1 2 3 3 3 0 MukF middle domain AAA_7 PF12775.7 KIK55427.1 - 0.041 13.4 0.3 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KIK55427.1 - 0.053 13.9 0.3 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK55427.1 - 0.06 13.3 1.9 0.17 11.8 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Mer2 PF09074.10 KIK55427.1 - 0.064 13.1 6.1 0.14 12.0 6.1 1.5 1 0 0 1 1 1 0 Mer2 PHY PF00360.20 KIK55427.1 - 0.098 12.0 1.1 0.52 9.6 0.1 2.6 3 1 0 3 3 3 0 Phytochrome region APS_kinase PF01583.20 KIK55427.1 - 0.1 12.5 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 KIK55427.1 - 0.18 11.9 1.9 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain PIN_8 PF18476.1 KIK55427.1 - 0.95 9.3 7.9 0.7 9.7 4.8 2.2 2 1 2 4 4 4 0 PIN like domain Tn7_Tnp_TnsA_C PF08721.11 KIK55427.1 - 3.5 8.3 5.4 22 5.8 0.2 3.0 3 0 0 3 3 3 0 TnsA endonuclease C terminal WD40 PF00400.32 KIK55428.1 - 7.1e-33 112.1 10.3 1.1e-11 45.1 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55428.1 - 2.1e-13 50.4 0.0 0.00053 20.2 0.0 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK55428.1 - 1.2e-10 41.0 0.5 0.17 11.9 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK55428.1 - 1.9e-05 24.6 0.1 0.34 10.6 0.0 3.2 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK55428.1 - 0.00024 20.5 0.0 1.2 8.4 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain Ret2_MD PF18528.1 KIK55428.1 - 0.00061 20.1 0.0 9.4 6.7 0.0 3.1 1 1 2 3 3 3 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PQQ_3 PF13570.6 KIK55428.1 - 0.00082 19.8 0.6 2.2 8.9 0.1 3.5 1 1 2 3 3 3 2 PQQ-like domain CHAP PF05257.16 KIK55428.1 - 0.00085 19.8 0.1 3.3 8.4 0.1 3.1 1 1 2 3 3 3 1 CHAP domain Proteasome_A_N PF10584.9 KIK55428.1 - 0.00088 18.9 0.7 16 5.3 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 KIK55428.1 - 0.0023 17.0 0.0 3.4 6.5 0.0 3.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4072 PF13284.6 KIK55428.1 - 0.0058 17.1 0.0 33 5.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) BBS2_Mid PF14783.6 KIK55428.1 - 0.0065 16.5 0.0 21 5.2 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KIK55428.1 - 0.013 15.4 0.9 12 6.1 0.0 3.9 4 1 0 4 4 4 0 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK55428.1 - 0.047 12.5 0.1 2.7 6.7 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Cuticle_4 PF15955.5 KIK55428.1 - 0.099 13.3 0.0 7.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Cuticle protein Nup160 PF11715.8 KIK55428.1 - 0.18 10.4 0.0 16 4.0 0.0 2.7 3 1 0 4 4 4 0 Nucleoporin Nup120/160 DUF1923 PF09083.10 KIK55428.1 - 0.77 9.5 4.3 24 4.7 0.6 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1923) F-box-like PF12937.7 KIK55431.1 - 0.00011 22.0 0.6 0.00034 20.4 0.6 1.9 1 0 0 1 1 1 1 F-box-like TEA PF01285.18 KIK55434.1 - 2.9e-22 78.5 0.0 5.1e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain GluR_Homer-bdg PF10606.9 KIK55435.1 - 5.8 7.2 8.9 9 6.6 1.6 3.3 3 0 0 3 3 3 0 Homer-binding domain of metabotropic glutamate receptor DUF3295 PF11702.8 KIK55436.1 - 5.7e-08 32.6 19.2 1.5e-07 31.1 17.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF5456 PF17539.2 KIK55436.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5456) AhpC-TSA_2 PF13911.6 KIK55437.1 - 4.5e-12 46.1 0.0 8.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KIK55437.1 - 0.0024 17.8 0.0 0.0035 17.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK55437.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin Trp_halogenase PF04820.14 KIK55438.1 - 3.8e-27 95.3 2.5 3.3e-14 52.6 0.3 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK55438.1 - 2.3e-15 56.7 0.1 3.5e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK55438.1 - 3e-08 33.4 0.1 5.1e-08 32.7 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK55438.1 - 5e-06 26.6 1.3 2.2e-05 24.6 0.2 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK55438.1 - 3.8e-05 23.1 0.0 5.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK55438.1 - 0.0004 20.9 0.2 0.0046 17.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK55438.1 - 0.00099 17.9 0.2 0.0014 17.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KIK55438.1 - 0.0029 16.7 0.6 0.0054 15.9 0.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK55438.1 - 0.0039 16.3 0.9 0.009 15.1 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK55438.1 - 0.0051 16.4 1.2 0.21 11.1 0.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KIK55438.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AvrD PF05655.11 KIK55438.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Pseudomonas avirulence D protein (AvrD) WD40 PF00400.32 KIK55440.1 - 7.2e-100 324.1 51.3 1.6e-10 41.4 0.1 10.6 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55440.1 - 2e-35 120.9 1.1 0.011 16.0 0.0 9.8 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK55440.1 - 7.4e-22 77.7 12.7 0.0068 15.4 0.0 9.7 1 1 8 10 10 10 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK55440.1 - 1.8e-14 53.2 20.4 0.94 9.5 0.0 9.5 9 0 0 9 9 9 6 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK55440.1 - 7.3e-06 24.9 18.5 2.6 6.6 0.0 8.7 3 3 5 9 9 9 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK55440.1 - 0.00025 20.5 0.0 18 4.5 0.0 5.8 4 2 3 7 7 7 0 WD40-like domain Cuticle_4 PF15955.5 KIK55440.1 - 0.00042 21.0 0.9 1.4e+02 3.2 0.0 7.0 8 0 0 8 8 8 0 Cuticle protein WD40_3 PF15911.5 KIK55440.1 - 0.0016 18.4 2.3 40 4.3 0.0 6.8 9 0 0 9 9 9 0 WD domain, G-beta repeat Ret2_MD PF18528.1 KIK55440.1 - 0.0059 17.0 0.1 92 3.5 0.0 5.4 4 1 2 6 6 6 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Phage_attach PF05354.11 KIK55440.1 - 0.011 15.6 5.1 0.11 12.3 0.1 4.0 3 3 1 4 4 4 0 Phage Head-Tail Attachment Frtz PF11768.8 KIK55440.1 - 0.024 12.9 0.0 8.6 4.5 0.0 3.9 3 2 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz 5-FTHF_cyc-lig PF01812.20 KIK55440.1 - 0.025 14.4 0.1 9.2 6.1 0.0 3.7 4 0 0 4 4 4 0 5-formyltetrahydrofolate cyclo-ligase family DpaA_N PF16924.5 KIK55440.1 - 0.15 12.2 0.0 36 4.5 0.0 3.8 3 2 1 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain GspH PF12019.8 KIK55440.1 - 0.49 10.8 24.7 48 4.4 5.1 7.2 1 1 4 5 5 5 0 Type II transport protein GspH NACHT PF05729.12 KIK55441.1 - 0.0014 18.6 0.1 0.0033 17.4 0.1 1.6 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK55441.1 - 0.0077 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KIK55441.1 - 0.024 14.8 0.1 0.027 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK55441.1 - 0.025 14.9 0.0 0.028 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK55441.1 - 0.028 14.9 0.4 0.035 14.6 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK55441.1 - 0.032 14.6 0.0 0.049 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KIK55441.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.5 1 1 1 2 2 2 0 NTPase AAA_5 PF07728.14 KIK55441.1 - 0.041 13.9 0.0 3.6 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIK55441.1 - 0.057 13.9 0.1 0.12 12.8 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK55441.1 - 0.062 13.8 0.0 0.08 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK55441.1 - 0.066 12.4 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KIK55441.1 - 0.077 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 KIK55441.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 KIK55441.1 - 0.18 11.5 0.1 0.26 11.0 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KIK55441.1 - 0.19 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KIK55441.1 - 0.22 11.2 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK55441.1 - 0.26 11.0 0.3 0.21 11.3 0.3 1.2 1 1 0 1 1 1 0 AAA domain Kelch_4 PF13418.6 KIK55442.1 - 0.082 12.9 0.3 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 Galactose oxidase, central domain PAT1 PF09770.9 KIK55444.1 - 5.7 5.1 13.3 7.4 4.7 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.32 KIK55445.1 - 1.7e-13 50.8 5.5 0.00019 22.1 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55445.1 - 0.00096 19.4 0.1 1.1 9.6 0.0 4.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BTB PF00651.31 KIK55447.1 - 1.7e-07 31.4 0.0 4.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.19 KIK55450.1 - 2.1e-09 37.6 7.5 9.8e-09 35.5 7.5 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK55450.1 - 2.6e-07 31.1 4.2 5.9e-07 30.0 4.2 1.5 1 0 0 1 1 1 1 HMG-box domain NmrA PF05368.13 KIK55452.1 - 3e-18 66.2 0.0 3.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55452.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK55452.1 - 3.1e-05 23.5 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK55452.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KIK55452.1 - 0.0042 17.5 0.0 0.0083 16.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIK55452.1 - 0.0062 15.7 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GFO_IDH_MocA PF01408.22 KIK55452.1 - 0.011 16.6 0.0 0.028 15.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2175 PF09943.9 KIK55452.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Shikimate_DH PF01488.20 KIK55452.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RCC1 PF00415.18 KIK55454.1 - 2.6e-46 156.0 17.3 6.6e-12 45.9 0.0 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK55454.1 - 1e-20 73.0 22.1 4e-06 26.5 0.2 6.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KIK55454.1 - 9.2e-12 44.7 4.4 9.2e-12 44.7 4.4 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 KIK55454.1 - 0.0036 17.2 3.1 0.012 15.5 3.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 TFIIF_beta PF02270.15 KIK55455.1 - 6.8e-27 93.4 0.1 1.1e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KIK55455.1 - 2.3e-19 70.4 0.0 3.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KIK55455.1 - 0.018 15.8 0.1 0.031 15.1 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain MFS_1 PF07690.16 KIK55456.1 - 0.0052 15.8 0.1 0.0073 15.3 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4013 PF13197.6 KIK55456.1 - 0.019 14.8 0.7 0.019 14.8 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) stn_TNFRSF12A PF12191.8 KIK55456.1 - 1.7 8.9 4.2 2.7 8.2 1.9 2.3 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Cep57_MT_bd PF06657.13 KIK55458.1 - 0.12 12.9 1.0 0.21 12.1 1.0 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DASH_Spc19 PF08287.11 KIK55459.1 - 0.075 12.9 3.4 0.12 12.3 3.4 1.2 1 0 0 1 1 1 0 Spc19 Tetraspanin PF00335.20 KIK55460.1 - 5.6 6.6 9.8 2.4 7.8 1.5 2.3 2 0 0 2 2 2 0 Tetraspanin family MFS_1 PF07690.16 KIK55461.1 - 1.3e-35 123.0 29.0 5.9e-35 120.8 30.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CitMHS PF03600.16 KIK55461.1 - 0.0058 15.9 0.2 0.0058 15.9 0.2 2.8 2 1 1 3 3 3 1 Citrate transporter adh_short_C2 PF13561.6 KIK55462.1 - 2.6e-46 158.1 0.0 3.4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK55462.1 - 1.4e-37 129.1 0.1 1.9e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK55462.1 - 3e-09 37.0 0.1 4.5e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK55462.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KIK55462.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PA PF02225.22 KIK55462.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 PA domain PEX11 PF05648.14 KIK55467.1 - 1.1e-14 54.4 2.3 5.2e-13 49.0 2.3 2.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3106 PF11304.8 KIK55467.1 - 0.094 13.2 1.2 0.19 12.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) p450 PF00067.22 KIK55470.1 - 3e-61 207.6 0.0 3.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK55476.1 - 1.2e-13 51.3 3.9 1.8e-09 38.1 0.1 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55476.1 - 5.9e-06 26.5 0.0 0.0017 18.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK55476.1 - 8.8e-05 22.0 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 2 WD40-like domain PD40 PF07676.12 KIK55476.1 - 0.0023 17.8 0.1 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK55476.1 - 0.0065 16.2 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Acetyltransf_1 PF00583.25 KIK55477.1 - 0.00066 19.9 0.0 0.00066 19.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK55477.1 - 0.16 11.9 0.0 0.17 11.9 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CVNH PF08881.10 KIK55480.1 - 4.7e-18 65.7 0.0 1.1e-05 26.1 0.0 3.4 2 1 1 3 3 3 3 CVNH domain NIT PF08376.10 KIK55480.1 - 0.0067 16.9 0.6 0.015 15.8 0.6 1.7 1 1 0 1 1 1 1 Nitrate and nitrite sensing CVNH PF08881.10 KIK55481.1 - 3e-19 69.6 0.0 9.7e-11 42.3 0.0 3.0 2 1 1 3 3 3 3 CVNH domain Regulator_TrmB PF11495.8 KIK55481.1 - 0.0024 17.1 0.3 0.079 12.1 0.1 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB CVNH PF08881.10 KIK55483.1 - 0.00019 22.1 0.1 0.00022 21.9 0.1 1.1 1 0 0 1 1 1 1 CVNH domain DUF2294 PF10057.9 KIK55484.1 - 0.019 15.1 1.0 5.5 7.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) ThiD2 PF17792.1 KIK55484.1 - 0.086 13.3 2.7 0.1 13.1 1.1 1.9 1 1 1 2 2 2 0 ThiD2 family Glyco_hydro_28 PF00295.17 KIK55486.1 - 5.4e-67 226.2 14.9 7.5e-67 225.7 14.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 KIK55487.1 - 4.4e-68 229.7 15.3 6.1e-68 229.3 15.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Hexokinase_2 PF03727.16 KIK55488.1 - 1.4e-83 280.1 0.0 1.7e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIK55488.1 - 8.6e-60 202.0 0.0 1.2e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase AMP-binding PF00501.28 KIK55489.1 - 8.7e-32 110.2 0.0 2.4e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK55489.1 - 1.2e-24 86.8 0.0 2.2e-23 82.7 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK55489.1 - 0.00049 19.6 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK55489.1 - 0.00066 20.0 0.0 0.006 16.9 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site PMI_typeI PF01238.21 KIK55490.1 - 1.9e-116 389.3 0.0 2.4e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KIK55490.1 - 0.00015 21.4 0.3 0.31 10.8 0.2 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KIK55490.1 - 0.0023 17.9 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KIK55490.1 - 0.072 12.8 0.1 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Cupin BTB PF00651.31 KIK55491.1 - 1.9e-08 34.5 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5386 PF17360.2 KIK55492.1 - 0.6 10.0 2.8 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5386) RNA_POL_M_15KD PF02150.16 KIK55494.1 - 2.9e-12 46.3 2.1 2.9e-12 46.3 2.1 3.6 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KIK55494.1 - 1.7e-11 43.8 1.3 1.7e-11 43.8 1.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 KIK55494.1 - 0.0023 17.3 8.9 0.98 8.9 0.3 4.1 4 0 0 4 4 4 2 zinc-ribbon domain Lar_restr_allev PF14354.6 KIK55494.1 - 0.0027 18.1 0.4 0.0027 18.1 0.4 2.2 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-3CxxC PF13695.6 KIK55494.1 - 0.0051 17.3 4.6 0.19 12.2 1.7 2.2 2 0 0 2 2 2 1 Zinc-binding domain GFA PF04828.14 KIK55494.1 - 0.0083 16.4 7.5 0.053 13.9 0.8 2.8 1 1 2 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.7 KIK55494.1 - 0.028 14.4 1.2 0.028 14.4 1.2 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain C1_1 PF00130.22 KIK55494.1 - 0.029 14.2 1.2 0.029 14.2 1.2 2.7 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KIK55494.1 - 0.054 13.1 11.7 0.43 10.2 0.1 3.5 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger eIF-5_eIF-2B PF01873.17 KIK55494.1 - 0.13 12.2 5.9 0.36 10.7 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.13 KIK55494.1 - 0.15 12.2 10.5 0.54 10.3 2.6 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DpnI PF06044.12 KIK55494.1 - 0.38 10.4 6.7 0.5 10.0 0.4 2.1 2 0 0 2 2 2 0 Dam-replacing family IBR PF01485.21 KIK55494.1 - 0.43 10.8 9.7 1.1e+02 3.1 9.7 2.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain RecR PF02132.15 KIK55494.1 - 0.44 10.2 12.6 0.44 10.2 2.3 3.6 3 1 0 3 3 3 0 RecR protein zinc_ribbon_12 PF11331.8 KIK55494.1 - 0.62 9.9 5.4 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 KIK55494.1 - 0.65 10.3 8.5 0.17 12.2 1.3 3.0 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase CpXC PF14353.6 KIK55494.1 - 0.71 9.9 8.5 2.2 8.3 1.1 2.9 3 1 0 3 3 2 0 CpXC protein zinc_ribbon_2 PF13240.6 KIK55494.1 - 0.78 9.5 10.8 4.1 7.3 0.8 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Rpr2 PF04032.16 KIK55494.1 - 0.96 9.8 6.9 27 5.1 7.0 2.3 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 KIK55494.1 - 1.5 9.0 12.2 2.5 8.3 0.2 3.6 4 0 0 4 4 4 0 Zinc ribbon domain HypA PF01155.19 KIK55494.1 - 2.3 8.3 8.5 2.6 8.1 4.1 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KIK55494.1 - 2.4 8.1 12.8 2 8.4 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 KIK55494.1 - 2.8 8.1 13.5 5.6 7.1 0.1 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-CHY PF05495.12 KIK55494.1 - 8.9 6.9 10.8 8.4e+02 0.6 10.8 2.7 1 1 0 1 1 1 0 CHY zinc finger Hydrophobin PF01185.18 KIK55495.1 - 3.8e-22 78.7 9.6 4.8e-22 78.4 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Plavaka PF18759.1 KIK55497.1 - 1.8e-79 267.3 1.0 2.2e-79 267.1 1.0 1.1 1 0 0 1 1 1 1 Plavaka transposase CLLAC PF15675.5 KIK55497.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.5 3 0 0 3 3 3 0 CLLAC-motif containing domain Fer4_3 PF12798.7 KIK55498.1 - 1.5 10.0 0.1 1.5 10.0 0.1 2.4 3 0 0 3 3 3 0 4Fe-4S binding domain Ank_2 PF12796.7 KIK55499.1 - 0.0033 18.0 0.1 0.007 16.9 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK55499.1 - 0.17 12.5 0.1 4.7 8.1 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeat BBE PF08031.12 KIK55502.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF3426 PF11906.8 KIK55502.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Glyco_hydro_31 PF01055.26 KIK55503.1 - 2.5e-86 290.6 2.3 3.8e-86 290.0 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 WD40 PF00400.32 KIK55504.1 - 7.3e-20 70.9 6.2 7.6e-05 23.4 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55504.1 - 9.3e-14 51.5 0.1 0.00013 22.2 0.0 5.3 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK55504.1 - 0.00057 19.8 0.1 0.41 10.5 0.1 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK55504.1 - 0.0026 17.7 2.9 0.11 12.4 0.1 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KIK55504.1 - 0.027 13.5 0.0 1.6 7.7 0.0 2.8 2 1 1 3 3 3 0 Coatomer WD associated region Ge1_WD40 PF16529.5 KIK55504.1 - 0.036 13.0 0.1 2.3 7.1 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup54 PF13874.6 KIK55505.1 - 1.4e-33 115.9 0.2 3.1e-33 114.8 0.2 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KIK55505.1 - 7.5e-12 45.9 120.9 1.4e-06 29.0 30.9 5.5 2 1 3 5 5 5 4 Nucleoporin FG repeat region Nup54_C PF18437.1 KIK55505.1 - 2.7e-05 24.0 1.1 2.7e-05 24.0 1.1 1.7 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain NADHdeh_related PF10125.9 KIK55505.1 - 1.2 8.5 2.8 5.1 6.4 0.4 2.5 2 1 1 3 3 3 0 NADH dehydrogenase I, subunit N related protein SGL PF08450.12 KIK55506.1 - 3.2e-27 95.7 0.0 5.4e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK55506.1 - 0.00011 22.3 0.2 0.0012 19.0 0.0 2.8 3 1 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.20 KIK55506.1 - 0.00049 20.2 0.0 0.0026 17.9 0.0 2.2 2 0 0 2 2 2 1 Arylesterase p450 PF00067.22 KIK55508.1 - 1.8e-45 155.5 0.0 3.8e-45 154.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Glyco_transf_21 PF13506.6 KIK55508.1 - 0.078 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 p450 PF00067.22 KIK55509.1 - 1.4e-41 142.7 0.0 2e-41 142.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK55510.1 - 0.00033 19.5 0.0 0.0017 17.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 ATP-synt PF00231.19 KIK55511.1 - 4.8e-78 262.7 3.2 5.4e-78 262.5 3.2 1.0 1 0 0 1 1 1 1 ATP synthase eIF-5_eIF-2B PF01873.17 KIK55512.1 - 3.5e-40 136.5 0.4 6.6e-40 135.6 0.4 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIK55512.1 - 0.01 15.3 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding IF2_N PF04760.15 KIK55512.1 - 0.019 14.8 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 KIK55512.1 - 0.042 13.6 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 HypF finger GAGE PF05831.11 KIK55512.1 - 0.3 11.7 2.5 0.32 11.5 1.0 1.8 1 1 0 1 1 1 0 GAGE protein EBV-NA3 PF05009.12 KIK55512.1 - 0.37 10.3 4.9 2.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Arc_trans_TRASH PF08394.10 KIK55512.1 - 0.63 10.4 3.5 14 6.1 0.0 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Fungal_trans PF04082.18 KIK55513.1 - 8.6e-20 70.9 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55513.1 - 2.4e-07 30.7 9.0 3.8e-07 30.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK55514.1 - 2.1e-05 23.7 0.5 2.3e-05 23.6 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIK55515.1 - 2.8e-09 36.4 0.1 4.2e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Interferon PF00143.19 KIK55515.1 - 0.0089 16.2 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 Interferon alpha/beta domain FPN1 PF06963.12 KIK55516.1 - 6.4e-82 275.4 8.4 1.1e-54 185.7 2.4 3.1 2 1 0 2 2 2 2 Ferroportin1 (FPN1) DUF5504 PF17608.2 KIK55516.1 - 0.064 13.4 0.1 0.23 11.6 0.0 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5504) CAP PF00188.26 KIK55517.1 - 2.8e-21 76.6 4.8 5.7e-21 75.6 4.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Abhydrolase_6 PF12697.7 KIK55519.1 - 1.7e-07 32.1 0.2 1.7e-07 32.1 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KIK55519.1 - 0.001 18.7 0.0 0.0027 17.4 0.0 1.8 2 1 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.8 KIK55519.1 - 0.0047 16.2 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK55520.1 - 6.2e-11 43.3 0.9 6.2e-11 43.3 0.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK55520.1 - 0.00019 20.8 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK55520.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KIK55520.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MRP-S32 PF10210.9 KIK55520.1 - 0.081 13.5 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Lipase_3 PF01764.25 KIK55520.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 KIK55520.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.32 KIK55522.1 - 3.8e-38 128.8 15.3 8.7e-09 35.9 0.0 8.3 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KIK55522.1 - 2.6e-07 30.4 0.6 6e-06 26.1 0.6 2.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK55522.1 - 9.2e-06 25.4 0.2 0.068 13.1 0.1 2.5 2 0 0 2 2 2 2 F-box domain ANAPC4_WD40 PF12894.7 KIK55522.1 - 0.00035 20.8 0.0 17 5.8 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK55522.1 - 0.0029 17.2 0.2 0.097 12.2 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 KIK55522.1 - 0.15 11.0 0.4 8.4 5.2 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK55522.1 - 0.19 10.3 10.2 2.8 6.5 0.0 5.0 4 2 1 6 6 6 0 Nucleoporin Nup120/160 Sec34 PF04136.15 KIK55523.1 - 0.075 12.9 1.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family Snapin_Pallidin PF14712.6 KIK55523.1 - 0.15 12.5 1.2 6.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin HAD_2 PF13419.6 KIK55524.1 - 2.9e-12 47.0 0.0 4.8e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK55524.1 - 1.4e-08 35.3 0.0 2.4e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK55524.1 - 0.00036 20.5 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans PF04082.18 KIK55525.1 - 2.2e-26 92.5 0.1 2.9e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Interferon PF00143.19 KIK55525.1 - 0.12 12.6 0.1 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Interferon alpha/beta domain Fungal_trans PF04082.18 KIK55527.1 - 1.9e-16 59.9 0.0 3.8e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Thr_synth_N PF14821.6 KIK55528.1 - 3.6e-27 94.4 0.0 1.1e-26 92.9 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KIK55528.1 - 2.3e-18 66.7 0.0 7.9e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KA1 PF02149.19 KIK55528.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 NAD_binding_4 PF07993.12 KIK55529.1 - 2.3e-32 112.2 0.0 4.1e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK55529.1 - 4.6e-31 107.9 0.0 8.7e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK55529.1 - 2e-05 24.2 0.0 0.00012 21.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIK55529.1 - 0.0012 18.8 0.1 0.0052 16.7 0.1 2.1 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 KIK55529.1 - 0.0052 17.1 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Phasin_2 PF09361.10 KIK55529.1 - 0.077 13.3 0.1 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Phasin protein MgpC PF05220.12 KIK55529.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 MgpC protein precursor FA_desaturase PF00487.24 KIK55531.1 - 6.5e-23 81.9 18.2 8.9e-23 81.4 18.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KIK55531.1 - 8.8e-19 66.7 0.2 1.5e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) NmrA PF05368.13 KIK55532.1 - 1.9e-29 102.9 0.0 2.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55532.1 - 1.9e-06 27.9 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding AAA_16 PF13191.6 KIK55533.1 - 0.0087 16.5 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RHSP PF07999.11 KIK55533.1 - 0.026 13.4 0.1 0.53 9.0 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon hot spot protein FtsK_SpoIIIE PF01580.18 KIK55533.1 - 0.046 13.1 0.2 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KIK55533.1 - 0.083 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KIK55533.1 - 0.13 12.1 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.7 KIK55533.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ADIP PF11559.8 KIK55535.1 - 3.5 7.7 5.0 7.5 6.6 0.8 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5373 PF17343.2 KIK55536.1 - 0.00013 21.8 2.7 0.076 12.9 0.5 2.6 1 1 1 2 2 2 2 Family of unknown function (DUF5373) F-box-like PF12937.7 KIK55537.1 - 2.3e-06 27.4 1.6 6.7e-06 25.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK55537.1 - 0.00015 21.5 0.8 0.00057 19.7 0.8 1.9 1 0 0 1 1 1 1 F-box domain DUF3969 PF13108.6 KIK55537.1 - 0.15 12.1 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) F-box_4 PF15966.5 KIK55537.1 - 0.31 10.9 1.9 0.65 9.9 0.4 2.3 2 1 0 2 2 2 0 F-box NmrA PF05368.13 KIK55538.1 - 8.7e-32 110.5 0.0 1.2e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55538.1 - 1.7e-08 34.5 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK55538.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK55539.1 - 2.8e-38 131.8 0.0 3.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55539.1 - 5.2e-13 49.3 0.0 7.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK55539.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CVNH PF08881.10 KIK55541.1 - 1.8e-20 73.5 0.0 2.2e-09 37.9 0.0 3.6 2 1 1 3 3 3 3 CVNH domain FIBP PF05427.11 KIK55541.1 - 0.015 14.6 0.5 0.022 14.1 0.5 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) Cactin_mid PF10312.9 KIK55541.1 - 0.02 14.7 0.7 0.033 13.9 0.7 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin DUF445 PF04286.12 KIK55541.1 - 0.023 14.5 0.8 0.033 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Gal_mutarotas_3 PF18080.1 KIK55541.1 - 0.044 13.7 2.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 Galactose mutarotase-like fold domain MetOD1 PF18546.1 KIK55541.1 - 0.1 12.5 0.9 0.2 11.6 0.9 1.5 1 0 0 1 1 1 0 Metanogen output domain 1 NmrA PF05368.13 KIK55542.1 - 9e-25 87.6 0.0 4.4e-23 82.0 0.0 2.5 3 0 0 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55542.1 - 3.3e-13 50.0 0.0 4.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK55542.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK55543.1 - 8e-36 123.8 0.0 9.8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55543.1 - 1.7e-12 47.6 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 KIK55545.1 - 1.1e-05 24.7 0.1 1.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55546.1 - 1.9e-06 27.9 7.3 2.3e-06 27.6 7.3 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RseC_MucC PF04246.12 KIK55546.1 - 0.16 11.9 0.9 0.17 11.8 0.9 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Chs7 PF12271.8 KIK55549.1 - 7.1e-75 252.0 5.6 8.3e-75 251.8 5.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone VEGFR-2_TMD PF17988.1 KIK55549.1 - 0.11 11.9 0.5 0.11 11.9 0.5 3.1 3 0 0 3 3 3 0 VEGFR-2 Transmembrane domain Zn_clus PF00172.18 KIK55550.1 - 7.2e-08 32.4 7.5 1.1e-07 31.8 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK55551.1 - 1.1e-08 34.5 5.2 6.5e-05 22.1 0.8 2.8 2 1 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIK55554.1 - 1.1e-22 80.4 0.9 1.2e-22 80.3 0.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 KIK55555.1 - 3e-32 112.1 0.0 3.2e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1648 PF07853.11 KIK55555.1 - 0.12 12.1 0.0 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Interferon PF00143.19 KIK55556.1 - 0.019 15.1 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain Fungal_trans PF04082.18 KIK55557.1 - 5.3e-24 84.7 0.1 1.3e-23 83.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 KIK55558.1 - 1.3e-23 83.8 0.0 1.6e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans PF04082.18 KIK55559.1 - 1.3e-23 83.4 0.1 2.8e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55559.1 - 2.2e-07 30.9 9.6 3.5e-07 30.2 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_cc PF11790.8 KIK55560.1 - 2.4e-57 194.2 0.1 2.9e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ribosomal_S30 PF04758.14 KIK55561.1 - 1.7e-29 101.8 7.3 1.9e-29 101.6 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pterin_bind PF00809.22 KIK55562.1 - 2e-45 155.4 0.0 1.7e-18 67.2 0.0 3.7 3 1 0 3 3 3 3 Pterin binding enzyme HPPK PF01288.20 KIK55562.1 - 1.1e-32 112.8 0.0 2.6e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 KIK55562.1 - 2.1e-25 89.4 0.0 1.7e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase Fungal_trans PF04082.18 KIK55563.1 - 4.2e-16 58.8 1.9 6.4e-16 58.2 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55563.1 - 1.8e-08 34.4 10.4 2.9e-08 33.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK55564.1 - 1.7e-24 86.3 0.8 2.3e-24 85.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Auxin_repressed PF05564.12 KIK55565.1 - 0.0079 16.9 0.1 0.011 16.4 0.1 1.2 1 0 0 1 1 1 1 Dormancy/auxin associated protein Prok-E2_A PF14457.6 KIK55565.1 - 0.054 13.1 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family A Fungal_trans PF04082.18 KIK55566.1 - 7.1e-11 41.6 0.2 9e-11 41.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_A_exo1 PF01612.20 KIK55567.1 - 1.9e-15 57.0 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Pep_deformylase PF01327.21 KIK55567.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Polypeptide deformylase Fungal_trans PF04082.18 KIK55568.1 - 7.5e-20 71.1 0.1 1.1e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIK55569.1 - 5e-18 65.1 1.0 6.9e-13 48.2 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55569.1 - 2e-07 31.0 8.3 3.2e-07 30.4 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK55570.1 - 1.2e-24 86.8 0.2 2e-24 86.1 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Npun_R1517 PF18068.1 KIK55570.1 - 0.13 12.6 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 Npun R1517 Peptidase_S24 PF00717.23 KIK55571.1 - 2.9e-08 33.5 0.0 4.9e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Abhydrolase_1 PF00561.20 KIK55572.1 - 1e-21 77.8 0.1 2.9e-21 76.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK55572.1 - 6.6e-14 53.0 1.5 8.5e-14 52.7 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK55572.1 - 8.9e-06 25.1 0.0 3.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 KIK55572.1 - 0.032 14.6 0.1 0.17 12.3 0.0 2.2 3 0 0 3 3 3 0 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK55573.1 - 1.1e-23 84.2 0.0 8.4e-22 78.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK55573.1 - 1.1e-14 55.5 0.3 1.4e-14 55.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK55573.1 - 3.6e-05 23.2 0.0 0.00017 21.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Imm49 PF15575.6 KIK55573.1 - 0.012 15.3 0.0 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 49 EHN PF06441.12 KIK55573.1 - 0.035 14.5 0.1 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF2048 PF09752.9 KIK55573.1 - 0.049 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 KIK55575.1 - 4.3e-22 79.0 0.0 1.1e-21 77.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK55575.1 - 4e-11 44.0 0.1 5.4e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK55575.1 - 6.7e-10 38.6 0.0 3.4e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK55575.1 - 0.00022 20.2 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK55575.1 - 0.00055 19.0 0.0 0.0008 18.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DUF1057 PF06342.12 KIK55575.1 - 0.0017 17.4 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 KIK55575.1 - 0.0035 17.1 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KIK55575.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family DHHA2 PF02833.14 KIK55576.1 - 2.5e-26 92.6 0.0 4.3e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KIK55576.1 - 3.4e-13 49.7 0.0 5.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DHH family DUF4010 PF13194.6 KIK55577.1 - 0.012 15.3 3.1 0.012 15.3 3.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) DUF3493 PF11998.8 KIK55577.1 - 0.31 11.2 2.5 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 MIP PF00230.20 KIK55578.1 - 1.2e-48 165.8 7.1 1.5e-48 165.5 7.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein G-alpha PF00503.20 KIK55579.1 - 2.6e-107 359.0 0.0 3.1e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK55579.1 - 1.6e-10 40.7 0.1 9.1e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK55579.1 - 0.0048 17.1 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIK55579.1 - 0.039 13.5 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIK55579.1 - 0.057 13.7 0.0 0.64 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 KIK55580.1 - 0.0012 18.7 7.8 0.0012 18.7 7.8 3.6 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KIK55580.1 - 0.12 12.3 5.5 0.98 9.4 0.1 3.8 4 0 0 4 4 4 0 F-box domain TPR_19 PF14559.6 KIK55581.1 - 5.9e-10 39.5 2.2 0.0027 18.2 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK55581.1 - 1.3e-08 35.3 0.6 0.022 15.4 0.5 3.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK55581.1 - 3.6e-08 33.6 5.8 0.034 15.0 0.0 4.8 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 KIK55581.1 - 1.4e-06 28.4 2.0 0.038 14.1 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK55581.1 - 1.8e-06 27.6 1.4 0.096 12.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK55581.1 - 2.7e-06 27.2 2.3 0.044 14.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK55581.1 - 0.00076 20.0 1.3 0.25 12.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK55581.1 - 0.0023 17.7 0.1 0.066 13.1 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 KIK55581.1 - 0.0029 16.7 0.2 0.0037 16.3 0.2 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KIK55581.1 - 0.0097 15.1 3.0 0.016 14.5 0.4 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK55581.1 - 0.028 14.8 0.0 8.8 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK55581.1 - 0.049 13.7 2.4 9.1 6.6 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat PRP8_domainIV PF12134.8 KIK55581.1 - 0.066 12.8 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 PRP8 domain IV core BTAD PF03704.17 KIK55581.1 - 0.12 12.8 2.6 4.8 7.6 0.0 2.6 2 1 1 3 3 2 0 Bacterial transcriptional activator domain TPR_11 PF13414.6 KIK55581.1 - 0.21 11.3 0.9 13 5.6 0.0 3.2 3 0 0 3 3 3 0 TPR repeat Arg_repressor PF01316.21 KIK55582.1 - 0.044 13.5 0.0 0.57 10.0 0.0 2.8 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain S-antigen PF05756.11 KIK55582.1 - 1.2 9.5 5.0 3 8.3 5.0 1.6 1 0 0 1 1 1 0 S-antigen protein F-box-like PF12937.7 KIK55583.1 - 0.0021 17.9 0.1 0.0043 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF1180 PF06679.12 KIK55583.1 - 1.7 9.0 5.3 35 4.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) NmrA PF05368.13 KIK55584.1 - 2.9e-33 115.4 0.0 3.8e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55584.1 - 4.7e-10 39.7 0.0 6.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK55585.1 - 6.1e-35 120.9 0.0 7.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55585.1 - 4.1e-11 43.1 0.0 5.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK55586.1 - 3e-34 118.6 0.0 8.7e-34 117.1 0.0 1.6 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KIK55586.1 - 4.5e-13 49.5 0.0 6.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK55586.1 - 0.00059 19.4 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK55586.1 - 0.044 12.8 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UbiA PF01040.18 KIK55587.1 - 8e-54 182.6 15.1 8.7e-54 182.5 14.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_L27e PF01777.18 KIK55588.1 - 1.5e-34 118.2 2.1 2e-34 117.8 2.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KIK55588.1 - 0.0066 16.4 0.4 0.015 15.2 0.4 1.6 1 0 0 1 1 1 1 KOW motif F-box-like PF12937.7 KIK55589.1 - 6.2e-07 29.2 0.4 1.6e-06 27.9 0.4 1.7 1 1 0 1 1 1 1 F-box-like GAS PF13851.6 KIK55589.1 - 0.012 15.0 0.3 0.016 14.5 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nsp1_C PF05064.13 KIK55589.1 - 0.021 14.6 0.4 0.053 13.3 0.2 1.6 1 1 0 1 1 1 0 Nsp1-like C-terminal region Prefoldin PF02996.17 KIK55589.1 - 0.03 14.2 0.3 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit V-SNARE PF05008.15 KIK55589.1 - 0.046 14.1 0.8 0.074 13.4 0.8 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.12 KIK55589.1 - 0.049 14.3 0.2 0.088 13.4 0.2 1.5 1 0 0 1 1 1 0 SlyX BRE1 PF08647.11 KIK55589.1 - 0.055 13.5 0.3 0.085 12.9 0.3 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Syntaxin-6_N PF09177.11 KIK55589.1 - 0.11 13.1 0.3 0.18 12.3 0.3 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal MscS_porin PF12795.7 KIK55589.1 - 0.14 11.6 0.9 0.29 10.6 1.0 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Nup54_57_C PF18570.1 KIK55589.1 - 0.25 11.0 4.5 0.21 11.2 2.0 2.1 1 1 1 2 2 2 0 NUP57/Nup54 C-terminal domain Metallophos PF00149.28 KIK55591.1 - 6.5e-13 49.6 0.5 1e-12 49.0 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KIK55592.1 - 5.4e-11 43.4 0.3 7.8e-11 42.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.17 KIK55593.1 - 9.1e-56 188.7 0.0 1.1e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 KIK55593.1 - 0.015 15.6 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain CCDC144C PF14915.6 KIK55594.1 - 0.015 14.4 0.1 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4781 PF16013.5 KIK55594.1 - 0.021 13.6 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) PEARLI-4 PF05278.12 KIK55594.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) adh_short_C2 PF13561.6 KIK55596.1 - 4.2e-50 170.5 0.6 6.1e-44 150.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK55596.1 - 2.1e-38 131.8 0.6 3.2e-29 101.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KIK55596.1 - 4.4e-05 23.5 0.8 0.00016 21.7 0.8 1.9 1 1 0 1 1 1 1 KR domain AAA_30 PF13604.6 KIK55596.1 - 0.026 14.2 0.3 0.94 9.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain Epimerase PF01370.21 KIK55596.1 - 0.14 11.6 0.0 0.84 9.0 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gal-3-0_sulfotr PF06990.11 KIK55596.1 - 0.15 11.0 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase HPP PF04982.13 KIK55597.1 - 1.2e-40 138.5 11.5 1e-39 135.5 8.5 2.1 2 0 0 2 2 2 2 HPP family Fe_bilin_red PF05996.12 KIK55598.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase F-box-like PF12937.7 KIK55599.1 - 9.7e-08 31.8 2.4 2.4e-07 30.5 2.4 1.7 1 0 0 1 1 1 1 F-box-like Nmad5 PF18757.1 KIK55599.1 - 0.081 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 FAA_hydro_N_2 PF18288.1 KIK55599.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 DUF4298 PF14131.6 KIK55599.1 - 0.18 11.8 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) F-box PF00646.33 KIK55599.1 - 3.1 7.8 6.6 3.9 7.5 4.2 2.3 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK55600.1 - 2.9e-08 33.5 3.0 2.9e-08 33.5 3.0 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK55600.1 - 0.032 14.1 8.8 0.16 11.9 2.6 3.6 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK55601.1 - 3.3e-06 26.9 4.2 3.3e-06 26.9 4.2 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK55601.1 - 0.15 12.0 9.1 12 5.9 0.5 3.7 3 0 0 3 3 3 0 F-box domain Methyltransf_23 PF13489.6 KIK55602.1 - 1.2e-09 38.2 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK55602.1 - 5.4e-07 30.2 0.0 8.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK55602.1 - 0.00052 19.4 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK55602.1 - 0.026 15.2 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HLH PF00010.26 KIK55603.1 - 3.2e-06 27.0 0.0 2e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNA_pol_3_Rpc31 PF11705.8 KIK55603.1 - 0.00067 20.0 2.4 0.00067 20.0 2.4 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 GCIP PF13324.6 KIK55603.1 - 0.24 11.0 3.4 0.35 10.4 3.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Fungal_trans PF04082.18 KIK55604.1 - 5.8e-30 104.2 0.2 1.1e-29 103.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55604.1 - 2.1e-08 34.1 9.6 3.6e-08 33.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RICTOR_N PF14664.6 KIK55604.1 - 0.0027 16.8 0.4 0.0047 16.0 0.4 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Methyltransf_25 PF13649.6 KIK55605.1 - 1e-05 26.1 0.0 2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK55605.1 - 1.5e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK55605.1 - 0.001 19.7 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK55605.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAD_binding_4 PF01565.23 KIK55607.1 - 3.3e-16 59.3 0.5 6.7e-16 58.3 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK55607.1 - 6.6e-09 35.7 0.1 1.4e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like BBE PF08031.12 KIK55608.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KIK55608.1 - 0.0012 18.6 6.3 0.24 11.1 0.2 2.7 2 1 1 3 3 3 2 FAD binding domain Pentapeptide PF00805.22 KIK55608.1 - 0.21 11.3 0.3 0.67 9.7 0.1 2.0 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) FAD_binding_4 PF01565.23 KIK55609.1 - 1.9e-18 66.5 0.9 3.8e-18 65.6 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK55609.1 - 1.8e-08 34.3 0.1 3.9e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Catalase PF00199.19 KIK55610.1 - 4.7e-32 111.6 0.0 7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK55610.1 - 1.8e-15 56.9 1.9 3e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive Catalase_C PF18011.1 KIK55610.1 - 1.5e-07 31.2 0.0 9.6e-07 28.6 0.0 2.1 1 1 1 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KIK55610.1 - 0.00079 19.3 0.1 0.053 13.3 0.0 2.4 1 1 1 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK55610.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 ThiJ/PfpI family-like bZIP_1 PF00170.21 KIK55612.1 - 0.005 16.9 6.5 0.33 11.1 1.3 2.2 1 1 1 2 2 2 2 bZIP transcription factor DUF1275 PF06912.11 KIK55612.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) HAUS2 PF15003.6 KIK55612.1 - 0.012 15.3 4.0 0.014 15.1 4.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 ZapB PF06005.12 KIK55612.1 - 0.032 14.7 8.2 0.6 10.6 7.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KIK55612.1 - 0.047 14.3 7.9 0.11 13.2 6.1 1.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF4923 PF16270.5 KIK55612.1 - 0.081 12.7 0.4 0.093 12.6 0.4 1.1 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) TSC22 PF01166.18 KIK55612.1 - 0.082 13.2 9.2 0.26 11.6 2.8 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family AAA_31 PF13614.6 KIK55612.1 - 0.088 12.7 0.4 0.098 12.6 0.4 1.0 1 0 0 1 1 1 0 AAA domain DUF2205 PF10224.9 KIK55612.1 - 0.14 12.2 4.0 0.16 11.9 3.3 1.5 1 1 0 1 1 1 0 Short coiled-coil protein bZIP_2 PF07716.15 KIK55612.1 - 0.98 9.6 11.0 1.2 9.2 3.3 2.5 1 1 3 4 4 4 0 Basic region leucine zipper DivIC PF04977.15 KIK55612.1 - 1.8 8.4 7.2 1.8 8.4 2.5 2.4 1 1 2 3 3 3 0 Septum formation initiator UPF0449 PF15136.6 KIK55612.1 - 2.5 8.6 5.8 5.4 7.5 1.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 IFT20 PF14931.6 KIK55613.1 - 0.019 15.1 1.7 0.025 14.8 1.7 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF5442 PF17514.2 KIK55614.1 - 0.15 12.2 0.6 2.4 8.4 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5442) GYD PF08734.11 KIK55614.1 - 0.16 11.9 0.9 16 5.5 0.1 2.2 1 1 1 2 2 2 0 GYD domain KDZ PF18758.1 KIK55617.1 - 0.00016 21.3 3.2 0.00018 21.2 3.2 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase IBR PF01485.21 KIK55620.1 - 1e-07 32.1 5.6 1e-07 32.1 5.6 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIK55620.1 - 6.9e-07 29.5 7.0 6.9e-07 29.5 7.0 4.1 3 2 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK55620.1 - 5.5e-06 26.3 1.0 5.5e-06 26.3 1.0 4.4 3 3 2 5 5 5 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK55620.1 - 1.9e-05 24.5 5.9 1.9e-05 24.5 5.9 3.9 2 1 1 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK55620.1 - 2.5e-05 24.1 6.0 2.5e-05 24.1 6.0 5.4 3 2 2 5 5 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK55620.1 - 0.00063 19.5 8.0 0.00063 19.5 8.0 6.0 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK55620.1 - 0.017 15.0 4.1 0.017 15.0 4.1 5.3 3 3 1 4 4 4 0 Prokaryotic RING finger family 4 VWA_2 PF13519.6 KIK55622.1 - 2.1e-12 47.6 0.0 7e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KIK55622.1 - 4.8e-07 28.3 0.9 7.6e-07 27.7 0.1 1.7 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) VWA PF00092.28 KIK55622.1 - 2.5e-05 24.6 0.0 0.00026 21.3 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.19 KIK55622.1 - 3e-05 23.4 0.0 7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain VWA_CoxE PF05762.14 KIK55622.1 - 0.0014 18.0 0.7 0.045 13.1 0.1 3.1 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KIK55622.1 - 0.056 13.5 0.0 0.71 9.9 0.0 2.5 2 0 0 2 2 2 0 vWA found in TerF C terminus AAA_18 PF13238.6 KIK55625.1 - 2.5e-06 28.1 0.0 3.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIK55625.1 - 0.00033 21.1 0.0 0.018 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK55625.1 - 0.0019 18.4 0.1 0.0058 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIK55625.1 - 0.0029 18.0 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK55625.1 - 0.0031 18.0 0.0 0.0042 17.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KIK55625.1 - 0.006 16.7 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK55625.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KIK55625.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KIK55625.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 KIK55625.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein SKI PF01202.22 KIK55625.1 - 0.017 15.3 0.0 0.032 14.3 0.0 1.5 2 0 0 2 2 1 0 Shikimate kinase PduV-EutP PF10662.9 KIK55625.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 KIK55625.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KIK55625.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KIK55625.1 - 0.021 15.2 0.1 0.054 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIK55625.1 - 0.024 14.6 0.1 0.06 13.3 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 KIK55625.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 KIK55625.1 - 0.027 14.7 0.1 0.043 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIK55625.1 - 0.041 13.0 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 KIK55625.1 - 0.042 13.8 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK55625.1 - 0.054 13.9 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KIK55625.1 - 0.067 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KIK55625.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_terminase PF10668.9 KIK55625.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage terminase small subunit Roc PF08477.13 KIK55625.1 - 0.1 12.8 0.6 0.34 11.1 0.1 2.0 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KIK55625.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KIK55625.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KIK55625.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase dNK PF01712.19 KIK55625.1 - 0.19 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Septin PF00735.18 KIK55625.1 - 0.21 10.8 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Septin SKI PF01202.22 KIK55626.1 - 0.0054 16.9 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KIK55626.1 - 0.0055 17.2 0.0 0.0084 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KIK55626.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase p450 PF00067.22 KIK55628.1 - 1.5e-73 248.1 0.0 1.7e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MMR_HSR1 PF01926.23 KIK55632.1 - 4.5e-06 26.7 0.0 8.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK55632.1 - 0.0021 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.6 KIK55632.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KIK55632.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KIK55632.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KIK55632.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK55632.1 - 0.096 12.6 0.1 0.37 10.7 0.0 1.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KIK55634.1 - 4.5e-05 23.5 0.0 0.00013 22.1 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KIK55634.1 - 0.004 16.6 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KIK55634.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK55634.1 - 0.014 15.5 0.1 0.032 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK55634.1 - 0.023 15.2 0.0 0.042 14.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Tropomodulin PF03250.14 KIK55634.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Tropomodulin PduV-EutP PF10662.9 KIK55634.1 - 0.033 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KIK55634.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KIK55634.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Retrotran_gag_2 PF14223.6 KIK55635.1 - 5.1e-14 52.1 0.1 7.2e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MMR_HSR1 PF01926.23 KIK55636.1 - 3.8e-05 23.7 0.0 0.0001 22.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KIK55636.1 - 0.0012 18.6 0.0 0.042 13.6 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 KIK55636.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 KIK55636.1 - 0.033 14.7 0.0 0.071 13.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIK55636.1 - 0.046 13.6 0.1 0.86 9.5 0.3 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIK55636.1 - 0.076 13.0 0.3 0.16 12.0 0.1 1.8 2 1 0 2 2 2 0 AAA domain Kinocilin PF15033.6 KIK55639.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Kinocilin protein Gly-zipper_Omp PF13488.6 KIK55639.1 - 0.02 14.9 2.4 0.02 14.9 2.4 1.9 2 0 0 2 2 2 0 Glycine zipper Romo1 PF10247.9 KIK55639.1 - 0.038 14.3 0.1 0.094 13.1 0.1 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Mid2 PF04478.12 KIK55639.1 - 0.044 13.6 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KIK55639.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family CD34_antigen PF06365.12 KIK55639.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TFIIIC_sub6 PF10419.9 KIK55640.1 - 2.6e-17 62.5 0.0 5.2e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain E1-E2_ATPase PF00122.20 KIK55640.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase DUF4551 PF15087.6 KIK55640.1 - 2.6 6.8 3.9 3.2 6.5 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SWIRM-assoc_2 PF16496.5 KIK55640.1 - 3.7 6.3 12.1 5.5 5.8 12.1 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal UAA PF08449.11 KIK55641.1 - 4.2e-71 239.6 7.6 4.9e-71 239.4 7.6 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KIK55641.1 - 0.00029 20.1 0.3 0.00049 19.4 0.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KIK55641.1 - 0.0029 16.6 0.5 0.005 15.8 0.5 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 KIK55641.1 - 0.017 14.3 11.2 0.1 11.8 11.2 2.0 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport EamA PF00892.20 KIK55641.1 - 0.019 15.2 27.8 0.076 13.2 8.5 3.0 3 0 0 3 3 3 0 EamA-like transporter family CorA PF01544.18 KIK55642.1 - 1.1e-13 51.2 4.0 1.2e-13 51.0 4.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3054 PF11255.8 KIK55642.1 - 0.0092 16.5 2.2 0.013 16.0 2.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3054) Kdo PF06293.14 KIK55643.1 - 0.00013 21.3 0.6 0.0002 20.8 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1 PF01926.23 KIK55646.1 - 3.7e-06 27.0 0.0 7.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK55646.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.6 KIK55646.1 - 0.011 15.8 0.3 0.028 14.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KIK55646.1 - 0.016 15.0 0.1 0.077 12.7 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KIK55646.1 - 0.037 13.9 0.1 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KIK55646.1 - 0.055 12.6 0.9 0.12 11.4 0.1 1.8 2 0 0 2 2 2 0 MCM P-loop domain AAA PF00004.29 KIK55646.1 - 0.09 13.2 0.1 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK55646.1 - 0.092 13.3 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 KIK55646.1 - 0.097 12.9 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK55646.1 - 0.1 13.0 0.1 0.25 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 KIK55648.1 - 4.7e-05 22.9 0.1 0.039 13.3 0.1 2.2 1 1 0 2 2 2 2 Protein kinase domain 7TM_GPCR_Sri PF10327.9 KIK55648.1 - 0.18 10.9 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri NTP_transf_3 PF12804.7 KIK55649.1 - 0.088 13.2 0.1 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Pkinase PF00069.25 KIK55650.1 - 1.8e-09 37.4 0.0 1.2e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK55650.1 - 0.0005 19.4 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2017 PF09438.10 KIK55651.1 - 0.095 12.6 0.0 0.93 9.3 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2017) Pkinase PF00069.25 KIK55652.1 - 1.2e-10 41.3 0.2 1.8e-06 27.5 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK55652.1 - 0.00017 20.9 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase NUDIX PF00293.28 KIK55653.1 - 8.1e-17 61.5 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIK55653.1 - 2.2e-10 41.1 0.1 4.8e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIK55653.1 - 0.0022 17.6 2.1 0.0061 16.2 2.1 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain CBF PF03914.17 KIK55657.1 - 1.2e-38 132.9 4.9 9e-38 130.0 0.0 2.9 3 0 0 3 3 3 2 CBF/Mak21 family Cnd1 PF12717.7 KIK55657.1 - 0.016 15.3 0.0 0.053 13.6 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Oxidored_FMN PF00724.20 KIK55658.1 - 1.1e-95 320.8 0.0 1.4e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf-NADH-PPase PF09297.11 KIK55659.1 - 0.0083 15.8 0.5 0.012 15.2 0.5 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KIK55659.1 - 0.044 13.5 0.2 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 KIK55659.1 - 0.065 13.6 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.6 KIK55659.1 - 0.082 12.3 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain APH PF01636.23 KIK55660.1 - 5.5e-14 52.7 0.2 7.6e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_9 PF10081.9 KIK55660.1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Gpi1 PF05024.15 KIK55662.1 - 4e-60 203.1 6.1 9.3e-60 201.9 6.1 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Asp PF00026.23 KIK55663.1 - 1.1e-42 146.5 9.7 3.5e-42 144.9 9.7 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55663.1 - 6.4e-05 23.3 2.2 0.0012 19.1 0.1 2.8 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal p450 PF00067.22 KIK55664.1 - 2.1e-69 234.5 0.0 2.4e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 KIK55665.1 - 1.7e-42 146.0 16.7 4.4e-42 144.6 16.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55665.1 - 1.3e-06 28.8 2.6 0.00021 21.6 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal DUF4636 PF15468.6 KIK55667.1 - 0.014 15.1 0.7 0.025 14.3 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Ras PF00071.22 KIK55669.1 - 1.5e-55 187.2 0.0 1.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK55669.1 - 2.8e-23 82.4 0.0 4.5e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK55669.1 - 2.2e-06 27.2 0.0 3.9e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK55669.1 - 0.0044 16.9 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KIK55669.1 - 0.035 13.5 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KIK55669.1 - 0.039 14.4 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KIK55669.1 - 0.13 11.8 0.0 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 KIK55669.1 - 0.15 11.4 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Asp PF00026.23 KIK55670.1 - 1.9e-48 165.5 19.6 5.4e-48 164.0 19.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55670.1 - 8.7e-10 39.1 5.3 0.00047 20.4 0.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK55670.1 - 0.03 14.1 0.2 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Abhydrolase_6 PF12697.7 KIK55672.1 - 0.00095 19.8 0.2 0.0014 19.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK55672.1 - 0.02 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIK55672.1 - 0.031 14.1 0.0 0.08 12.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Asp PF00026.23 KIK55673.1 - 1.8e-44 152.5 12.2 4.2e-44 151.3 12.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55673.1 - 7.5e-07 29.6 1.9 0.00074 19.8 0.1 2.9 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK55673.1 - 0.029 15.0 5.8 0.096 13.3 0.9 3.1 3 0 0 3 3 3 0 Aspartyl protease DUF2528 PF10800.8 KIK55673.1 - 0.14 12.7 0.0 0.92 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) gag-asp_proteas PF13975.6 KIK55673.1 - 0.15 12.7 1.6 0.41 11.2 0.2 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KIK55674.1 - 6.6e-32 111.2 7.9 3.9e-31 108.6 7.9 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55674.1 - 0.036 14.3 0.4 0.095 12.9 0.1 2.0 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Asp PF00026.23 KIK55675.1 - 1e-42 146.7 8.0 2.9e-42 145.2 8.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55675.1 - 9.8e-08 32.4 0.4 0.00033 20.9 0.1 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK55675.1 - 0.051 14.2 2.6 1.5 9.6 0.2 3.1 2 1 0 2 2 2 0 Aspartyl protease Glyco_hydro_cc PF11790.8 KIK55677.1 - 4.2e-26 92.0 0.0 5e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 KIK55679.1 - 5e-34 117.9 0.1 5.8e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ABC1 PF03109.16 KIK55680.1 - 2.1e-27 95.7 0.0 5.7e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 ABC1 family polyprenyl_synt PF00348.17 KIK55682.1 - 8.8e-46 156.0 0.0 1.6e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KIK55682.1 - 0.00054 19.4 1.1 0.038 13.3 0.1 2.7 3 0 0 3 3 3 2 Terpene synthase family, metal binding domain Filament PF00038.21 KIK55685.1 - 0.0077 15.8 62.3 0.071 12.7 11.0 2.2 2 0 0 2 2 2 2 Intermediate filament protein DUF4055 PF13264.6 KIK55685.1 - 0.01 16.0 1.8 0.01 16.0 1.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) bZIP_1 PF00170.21 KIK55685.1 - 0.013 15.6 2.4 0.013 15.6 2.4 6.3 4 2 3 7 7 7 0 bZIP transcription factor TolA_bind_tri PF16331.5 KIK55685.1 - 0.016 15.3 5.4 0.016 15.3 5.4 6.3 4 3 2 7 7 7 0 TolA binding protein trimerisation DivIC PF04977.15 KIK55685.1 - 0.019 14.7 4.1 0.019 14.7 4.1 7.3 4 2 2 7 7 7 0 Septum formation initiator bZIP_2 PF07716.15 KIK55685.1 - 0.024 14.7 1.9 0.024 14.7 1.9 6.6 5 2 1 6 6 6 0 Basic region leucine zipper YabA PF06156.13 KIK55685.1 - 1.5 9.5 60.4 0.34 11.6 5.1 6.5 2 2 5 7 7 7 0 Initiation control protein YabA Fez1 PF06818.15 KIK55685.1 - 5.5 7.4 64.2 0.3 11.5 16.7 3.6 2 1 0 4 4 4 0 Fez1 DUF1635 PF07795.11 KIK55686.1 - 0.44 10.4 2.7 0.47 10.3 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Lys PF00062.20 KIK55687.1 - 0.06 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Drf_DAD PF06345.11 KIK55687.1 - 0.1 12.7 0.5 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 DRF Autoregulatory Domain PHD PF00628.29 KIK55688.1 - 8.3e-05 22.4 9.4 8.3e-05 22.4 9.4 2.6 3 0 0 3 3 3 1 PHD-finger Prok-E2_D PF14460.6 KIK55688.1 - 0.092 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family D gag_pre-integrs PF13976.6 KIK55689.1 - 5e-08 32.7 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KIK55689.1 - 0.015 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain polyprenyl_synt PF00348.17 KIK55691.1 - 3.6e-46 157.3 0.0 7.2e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase tRNA-synt_1 PF00133.22 KIK55692.1 - 1.7e-10 39.8 0.1 2.5e-07 29.3 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Mog1 PF04603.12 KIK55693.1 - 0.014 15.7 1.9 0.28 11.5 0.0 2.6 3 0 0 3 3 3 0 Ran-interacting Mog1 protein polyprenyl_synt PF00348.17 KIK55694.1 - 5.5e-46 156.7 0.0 7.6e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase tRNA-synt_1 PF00133.22 KIK55696.1 - 1.1e-216 720.8 0.0 1.4e-215 717.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK55696.1 - 4.2e-34 117.7 0.1 8e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIK55696.1 - 3.1e-13 49.3 0.0 4.9e-06 25.5 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KIK55696.1 - 4.8e-10 39.2 0.1 2e-06 27.5 0.1 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KIK55696.1 - 0.03 13.7 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 KIK55696.1 - 0.21 11.9 6.0 0.31 11.3 2.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Pkinase PF00069.25 KIK55697.1 - 1.6e-07 31.0 0.1 1.2e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK55697.1 - 1.5e-05 24.4 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ABC2_membrane PF01061.24 KIK55699.1 - 2.5e-85 285.2 56.5 4.6e-49 166.7 23.6 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIK55699.1 - 8.4e-38 130.0 0.0 1.3e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIK55699.1 - 4.5e-32 109.8 14.4 3.8e-31 106.8 0.1 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK55699.1 - 1.1e-17 64.4 0.0 4.3e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KIK55699.1 - 1.1e-08 34.6 45.9 0.00012 21.4 17.0 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KIK55699.1 - 4e-08 33.1 1.6 4.2e-07 29.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIK55699.1 - 1.4e-06 28.4 0.0 0.27 11.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIK55699.1 - 3.4e-06 27.5 0.2 0.0071 16.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK55699.1 - 3.6e-05 23.7 0.2 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KIK55699.1 - 9.5e-05 22.9 0.1 0.11 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK55699.1 - 0.00029 20.5 0.9 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK55699.1 - 0.00036 20.8 0.3 1.5 9.1 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KIK55699.1 - 0.00041 20.5 0.1 0.39 10.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIK55699.1 - 0.00046 20.5 0.3 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK55699.1 - 0.012 15.4 1.2 2.7 7.7 0.4 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KIK55699.1 - 0.012 15.1 0.1 0.61 9.5 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIK55699.1 - 0.013 15.1 2.3 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIK55699.1 - 0.03 14.3 1.9 1.8 8.4 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KIK55699.1 - 0.032 14.1 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KIK55699.1 - 0.048 13.4 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIK55699.1 - 0.05 14.0 1.2 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK55699.1 - 0.095 13.1 0.1 25 5.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK55699.1 - 0.15 12.5 0.1 0.43 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KIK55699.1 - 0.19 11.5 0.1 18 5.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Mid1 PF12929.7 KIK55700.1 - 1.2e-58 199.4 0.0 1.6e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KIK55700.1 - 0.00019 22.0 3.2 0.035 14.7 0.3 2.5 2 0 0 2 2 2 2 Fz domain peroxidase PF00141.23 KIK55701.1 - 4.7e-19 69.0 0.0 8.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase p450 PF00067.22 KIK55702.1 - 6.3e-69 232.9 0.0 7.7e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ran_BP1 PF00638.18 KIK55703.1 - 5.5e-15 55.7 0.0 9.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain polyprenyl_synt PF00348.17 KIK55704.1 - 4.1e-48 163.7 0.0 9.3e-48 162.5 0.0 1.6 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KIK55704.1 - 2.8e-07 30.2 0.2 2e-05 24.1 0.2 2.4 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Herpes_U44 PF04533.13 KIK55704.1 - 0.1 12.2 0.4 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Herpes virus U44 protein YIF1 PF03878.15 KIK55705.1 - 1.5e-88 296.3 2.8 1.9e-88 296.0 2.8 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KIK55705.1 - 5.6e-06 26.2 3.5 1.1e-05 25.2 3.5 1.4 1 0 0 1 1 1 1 Yip1 domain RRP7 PF12923.7 KIK55707.1 - 0.059 13.5 0.6 0.093 12.9 0.1 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain zf-C2H2 PF00096.26 KIK55709.1 - 1.9e-08 34.3 15.0 0.00092 19.5 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK55709.1 - 2.4e-07 31.0 17.6 0.0021 18.7 0.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK55709.1 - 0.0012 19.1 3.6 0.076 13.3 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KIK55709.1 - 0.023 15.0 10.5 0.033 14.5 8.0 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KIK55709.1 - 0.072 13.1 14.4 0.47 10.5 2.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KIK55709.1 - 0.14 12.5 1.9 2.8 8.5 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KIK55709.1 - 0.4 10.5 7.0 1.2 8.9 0.5 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type SRP9-21 PF05486.12 KIK55711.1 - 1.3e-09 38.3 5.2 2.7e-09 37.3 0.8 2.5 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 KIK55711.1 - 0.0088 16.0 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Mito_carr PF00153.27 KIK55712.1 - 4.6e-60 199.6 0.1 4e-22 77.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.12 KIK55712.1 - 0.038 14.4 1.7 0.25 11.8 0.0 2.9 3 0 0 3 3 3 0 The GLUG motif PAE PF03283.13 KIK55712.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Tim17 PF02466.19 KIK55712.1 - 0.21 11.9 0.8 1.1 9.7 0.8 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 KIK55713.1 - 7.3e-71 232.3 19.0 1.5e-11 44.6 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55713.1 - 2e-19 69.6 1.4 0.053 13.8 0.0 7.0 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK55713.1 - 5.4e-12 46.0 0.3 3.1e-05 24.0 0.0 4.2 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK55713.1 - 3e-09 36.1 8.2 0.18 10.4 0.0 6.4 2 2 3 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK55713.1 - 1.3e-07 31.2 1.2 5.6 6.2 0.0 5.5 5 1 1 6 6 6 3 WD40-like domain PD40 PF07676.12 KIK55713.1 - 2.9e-07 30.2 0.0 21 5.2 0.0 6.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK55713.1 - 3.6e-06 26.2 2.0 1.4 7.8 0.1 5.2 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK55713.1 - 3.5e-05 23.6 7.1 8.7 6.3 0.1 6.5 7 0 0 7 7 7 2 Nitrous oxide reductase propeller repeat DsbC_N PF10411.9 KIK55713.1 - 5.2e-05 22.6 3.9 9.7 5.7 0.0 6.0 5 1 1 6 6 6 1 Disulfide bond isomerase protein N-terminus DUF5122 PF17164.4 KIK55713.1 - 0.00026 21.2 2.3 20 5.6 0.0 5.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller NHL PF01436.21 KIK55713.1 - 0.00026 20.9 6.6 52 4.1 0.0 6.8 7 0 0 7 7 7 0 NHL repeat Phage_sheath_1 PF04984.14 KIK55713.1 - 0.047 13.5 2.5 5 7.0 0.0 4.2 5 0 0 5 5 5 0 Phage tail sheath protein subtilisin-like domain Cuticle_4 PF15955.5 KIK55713.1 - 0.076 13.7 0.8 79 4.1 0.0 4.0 4 0 0 4 4 4 0 Cuticle protein CHAP PF05257.16 KIK55713.1 - 0.28 11.8 26.7 6.4 7.4 0.1 6.0 4 2 2 6 6 6 0 CHAP domain Pectate_lyase_3 PF12708.7 KIK55713.1 - 0.32 10.8 11.6 4.9 6.9 0.8 4.8 2 2 2 5 5 5 0 Pectate lyase superfamily protein GCV_T_C PF08669.11 KIK55713.1 - 0.85 9.6 9.4 6.9 6.7 0.3 4.6 4 1 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain NACHT PF05729.12 KIK55714.1 - 2e-07 31.1 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK55714.1 - 7.3e-06 26.5 0.0 2.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK55714.1 - 1.8e-05 25.2 1.2 0.0027 18.2 1.6 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK55714.1 - 0.013 15.1 0.1 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Endonuc-BsobI PF09194.10 KIK55714.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BsobI Tnp_P_element_C PF12596.8 KIK55714.1 - 0.028 15.0 0.2 0.046 14.3 0.2 1.4 1 0 0 1 1 1 0 87kDa Transposase GhoS PF11080.8 KIK55714.1 - 0.068 13.2 0.1 0.52 10.3 0.0 2.2 1 1 1 2 2 2 0 Endoribonuclease GhoS DUF815 PF05673.13 KIK55714.1 - 0.085 12.0 0.8 2.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KIK55714.1 - 0.11 13.0 0.1 0.68 10.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain VbhA PF18495.1 KIK55714.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Antitoxin VbhA PEMT PF04191.13 KIK55717.1 - 8.1e-25 87.3 1.0 8.1e-25 87.3 1.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase SKICH PF17751.1 KIK55717.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 SKICH domain MULE PF10551.9 KIK55719.1 - 5.9e-11 42.6 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain WRW PF10206.9 KIK55719.1 - 0.028 14.8 0.2 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f PEMT PF04191.13 KIK55721.1 - 3.7e-23 81.9 0.9 4.2e-23 81.7 0.9 1.0 1 0 0 1 1 1 1 Phospholipid methyltransferase Peptidase_M54 PF07998.11 KIK55721.1 - 0.07 13.1 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DDE_3 PF13358.6 KIK55722.1 - 0.00022 21.0 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Spt5_N PF11942.8 KIK55725.1 - 0.026 15.5 1.1 0.039 14.9 1.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PGC7_Stella PF15549.6 KIK55727.1 - 2.8 7.9 5.9 6.4 6.7 5.9 1.7 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain Ribosomal_S20p PF01649.18 KIK55728.1 - 0.4 11.3 6.4 0.57 10.9 4.6 2.1 1 1 0 1 1 1 0 Ribosomal protein S20 KDZ PF18758.1 KIK55729.1 - 1.1e-22 80.7 2.4 1.2e-22 80.6 2.4 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Xan_ur_permease PF00860.20 KIK55729.1 - 0.075 11.7 0.0 0.088 11.5 0.0 1.1 1 0 0 1 1 1 0 Permease family UPF0122 PF04297.14 KIK55731.1 - 0.14 12.4 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DUF1192 PF06698.11 KIK55734.1 - 0.028 14.5 1.2 0.079 13.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) OmpH PF03938.14 KIK55734.1 - 0.069 13.5 5.5 0.1 12.9 5.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 KIK55734.1 - 0.083 12.9 5.1 0.12 12.4 5.1 1.3 1 0 0 1 1 1 0 FlxA-like protein LMBR1 PF04791.16 KIK55734.1 - 0.26 10.2 2.8 0.29 10.0 2.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Lebercilin PF15619.6 KIK55734.1 - 0.44 10.2 12.9 0.11 12.1 8.2 1.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GTA_holin_3TM PF11351.8 KIK55734.1 - 0.79 10.3 3.2 0.51 10.9 1.2 1.7 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release TMF_DNA_bd PF12329.8 KIK55734.1 - 1.2 9.2 15.0 3.2 7.8 11.5 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CxC4 PF18717.1 KIK55737.1 - 1.4e-40 138.2 0.1 1.9e-40 137.7 0.1 1.2 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK55738.1 - 0.00039 20.1 2.1 0.00051 19.7 2.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Glyco_transf_25 PF01755.17 KIK55738.1 - 0.24 11.2 2.4 0.38 10.6 2.4 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) HAP2-GCS1 PF10699.9 KIK55739.1 - 0.051 13.6 0.6 0.051 13.6 0.6 2.1 2 0 0 2 2 2 0 Male gamete fusion factor Hid1 PF12722.7 KIK55740.1 - 3.5 5.6 6.2 4.3 5.3 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CGI-121 PF08617.10 KIK55743.1 - 0.042 14.0 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Kinase binding protein CGI-121 WD40 PF00400.32 KIK55746.1 - 2.3e-28 97.8 5.3 1.5e-09 38.3 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK55746.1 - 2.5e-11 43.7 0.0 0.0097 16.2 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK55746.1 - 3.7e-05 23.5 1.8 0.2 11.6 0.0 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK55746.1 - 0.00057 19.3 0.0 0.24 10.7 0.0 2.3 2 1 0 2 2 2 2 WD40-like domain Gmad1 PF10647.9 KIK55746.1 - 0.00068 19.5 0.2 0.12 12.1 0.1 2.6 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK55746.1 - 0.0026 16.5 0.0 3.2 6.3 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK55746.1 - 0.0032 16.5 0.1 12 4.7 0.0 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5018 PF16410.5 KIK55746.1 - 0.0042 15.9 0.0 0.0052 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5018) DUF4784 PF16023.5 KIK55746.1 - 0.0056 15.7 0.0 0.59 9.0 0.0 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4784) Peptidase_S9_N PF02897.15 KIK55746.1 - 0.074 11.8 0.0 4.8 5.9 0.0 2.6 1 1 2 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK55746.1 - 0.1 10.9 0.0 2.5 6.3 0.0 2.3 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4072 PF13284.6 KIK55746.1 - 0.1 13.0 0.0 29 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) BBS2_Mid PF14783.6 KIK55746.1 - 0.16 12.0 0.0 22 5.1 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Cuticle_4 PF15955.5 KIK55746.1 - 0.16 12.7 0.1 6.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Cuticle protein Proteasome_A_N PF10584.9 KIK55746.1 - 0.81 9.4 5.7 16 5.3 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1048 PF06304.11 KIK55747.1 - 0.0048 17.3 0.1 0.0099 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) Glycophorin_A PF01102.18 KIK55748.1 - 0.016 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A LrgB PF04172.16 KIK55751.1 - 0.33 10.4 11.5 0.32 10.5 8.7 2.3 2 1 0 2 2 2 0 LrgB-like family COesterase PF00135.28 KIK55752.1 - 5.1e-08 32.2 2.3 3.7e-07 29.4 2.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KIK55753.1 - 5.1e-36 124.6 0.0 5.5e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK55753.1 - 2.3e-05 24.3 0.0 2.7e-05 24.1 0.0 1.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK55753.1 - 0.00071 19.1 0.0 0.00082 18.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DDE_3 PF13358.6 KIK55754.1 - 0.027 14.2 0.3 0.039 13.7 0.3 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease CBF PF03914.17 KIK55754.1 - 0.17 11.9 0.3 0.39 10.7 0.1 1.6 1 1 1 2 2 2 0 CBF/Mak21 family COesterase PF00135.28 KIK55755.1 - 6.2e-27 94.6 0.0 6.7e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Fib_alpha PF08702.10 KIK55757.1 - 1.6e-05 25.2 2.9 0.0081 16.3 1.0 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KIK55757.1 - 1.9e-05 24.9 4.7 0.021 15.1 0.6 2.3 1 1 1 2 2 2 2 Csm1 N-terminal domain HMMR_N PF15905.5 KIK55757.1 - 0.0016 18.0 8.3 0.0019 17.7 8.3 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Phage_GP20 PF06810.11 KIK55757.1 - 0.0026 17.6 4.6 0.11 12.4 0.3 2.1 1 1 1 2 2 2 2 Phage minor structural protein GP20 PKcGMP_CC PF16808.5 KIK55757.1 - 0.0041 16.9 6.6 0.068 13.0 1.4 2.9 2 1 1 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Tam41_Mmp37 PF09139.11 KIK55757.1 - 0.0093 15.4 0.7 0.012 15.1 0.7 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Peptidase_S49_N PF08496.10 KIK55757.1 - 0.012 15.7 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF641 PF04859.12 KIK55757.1 - 0.02 15.2 5.8 0.56 10.6 5.1 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KIK55757.1 - 0.027 13.4 9.2 0.031 13.2 9.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KIK55757.1 - 0.029 14.2 5.4 0.039 13.8 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Mei5 PF10376.9 KIK55757.1 - 0.11 12.3 6.9 0.13 12.2 6.9 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein HIP1_clath_bdg PF16515.5 KIK55757.1 - 0.18 12.4 8.6 4.4 8.0 8.6 2.2 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KIK55757.1 - 0.39 11.4 6.0 1.3 9.7 1.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 KIK55757.1 - 0.48 10.6 9.2 3.4 7.8 1.4 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KIK55757.1 - 0.58 10.3 8.9 0.35 11.0 1.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 KIK55757.1 - 1.9 9.1 15.2 0.28 11.7 5.0 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Dzip-like_N PF13815.6 KIK55757.1 - 2.5 8.1 9.4 2.8 7.9 3.2 2.0 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal COesterase PF00135.28 KIK55759.1 - 2.7e-35 122.2 0.0 2.9e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK55759.1 - 2.2e-05 24.4 0.0 2.8e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK55759.1 - 0.0012 18.4 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KIK55760.1 - 8.1e-35 120.7 0.0 8.7e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK55760.1 - 2.3e-05 24.4 0.0 3.5e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK55760.1 - 0.00065 19.2 0.0 0.00079 19.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KIK55761.1 - 2.6e-16 59.6 0.0 3.2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family ABC_membrane PF00664.23 KIK55762.1 - 1.7e-59 201.7 27.8 5.6e-30 104.9 17.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK55762.1 - 8.8e-47 159.1 0.0 1.8e-26 93.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK55762.1 - 3.9e-07 29.7 0.1 0.0091 15.5 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK55762.1 - 5.2e-06 26.5 7.0 0.44 10.3 0.1 4.3 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIK55762.1 - 5.3e-06 26.5 1.1 0.038 14.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK55762.1 - 0.00029 20.5 0.5 0.29 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK55762.1 - 0.00095 19.1 0.2 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KIK55762.1 - 0.0033 17.0 0.1 0.6 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK55762.1 - 0.0037 17.7 0.6 2.1 8.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIK55762.1 - 0.0051 17.3 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK55762.1 - 0.01 16.0 0.2 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KIK55762.1 - 0.037 13.2 0.5 0.43 9.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KIK55762.1 - 0.046 13.8 2.9 0.33 11.0 0.7 2.4 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KIK55762.1 - 0.13 12.0 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KIK55762.1 - 0.14 12.4 0.8 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KIK55762.1 - 0.19 11.6 1.8 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KIK55762.1 - 0.21 10.7 0.6 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIK55762.1 - 0.27 11.5 4.2 3.4 7.9 0.1 3.1 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KIK55763.1 - 1.8e-30 105.9 0.0 4.5e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55763.1 - 1.9e-07 31.1 10.0 3.4e-07 30.3 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMT PF02366.18 KIK55765.1 - 2.4e-80 269.7 14.4 4.1e-80 268.9 14.4 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIK55765.1 - 1.5e-65 220.6 7.0 1.5e-65 220.6 7.0 2.0 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIK55765.1 - 7.9e-39 133.4 0.0 1.3e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIK55765.1 - 8.4e-06 26.1 9.6 8.4e-06 26.1 9.6 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2628 PF10947.8 KIK55765.1 - 8.5 6.8 6.8 7.3 7.0 2.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Inhibitor_I66 PF16850.5 KIK55767.1 - 2e-23 82.9 0.1 2.4e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Tyrosinase PF00264.20 KIK55768.1 - 1.2e-17 64.9 0.1 1.6e-17 64.6 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Helicase_C PF00271.31 KIK55770.1 - 5e-06 26.8 0.0 5e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PMT_4TMC PF16192.5 KIK55771.1 - 4.9e-32 111.2 0.1 6.1e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase Inhibitor_I66 PF16850.5 KIK55772.1 - 5.7e-23 81.4 0.1 7e-23 81.1 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Tyrosinase PF00264.20 KIK55773.1 - 1.3e-14 55.0 0.0 2.7e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 Common central domain of tyrosinase Tyrosinase PF00264.20 KIK55774.1 - 7.1e-17 62.4 0.1 9.2e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_S10 PF00450.22 KIK55777.1 - 7e-73 246.4 0.0 2.2e-72 244.8 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase SNO PF01174.19 KIK55778.1 - 4.8e-48 163.5 0.0 1.7e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIK55778.1 - 1.9e-07 30.9 0.0 2.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KIK55778.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 KIK55778.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 DUF1611_N PF17396.2 KIK55778.1 - 0.12 12.6 0.0 23 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DUF3113 PF11310.8 KIK55780.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) zf-RING_5 PF14634.6 KIK55781.1 - 0.002 18.0 10.9 0.0031 17.4 10.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK55781.1 - 0.012 15.4 11.6 0.019 14.8 11.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK55781.1 - 0.37 10.7 10.6 0.61 10.0 10.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C5HCH PF17982.1 KIK55781.1 - 1.7 8.9 13.2 3.8 7.8 11.3 2.1 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-AN1 PF01428.16 KIK55781.1 - 5.7 7.2 13.9 4.7 7.5 10.9 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger Inhibitor_I66 PF16850.5 KIK55782.1 - 1.7e-26 92.9 0.0 2.1e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 DNA_pol_A_exo1 PF01612.20 KIK55783.1 - 0.1 12.3 0.0 0.42 10.3 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease AT_hook PF02178.19 KIK55783.1 - 9.7 6.5 9.4 8.9 6.6 0.4 2.8 2 0 0 2 2 2 0 AT hook motif Inhibitor_I66 PF16850.5 KIK55786.1 - 4.1e-33 114.3 0.0 5e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 DUF1097 PF06496.11 KIK55788.1 - 0.047 13.8 6.0 0.05 13.7 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) EIIC-GAT PF03611.14 KIK55788.1 - 0.44 9.6 5.1 0.44 9.6 5.1 1.0 1 0 0 1 1 1 0 PTS system sugar-specific permease component YcgR_2 PF12945.7 KIK55789.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein YcgR YcgR_2 PF12945.7 KIK55792.1 - 0.088 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein YcgR Inhibitor_I66 PF16850.5 KIK55793.1 - 1.8e-29 102.5 0.1 2.1e-29 102.2 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 OprB PF04966.12 KIK55794.1 - 0.058 12.8 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family YcgR_2 PF12945.7 KIK55795.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein YcgR YcgR_2 PF12945.7 KIK55797.1 - 0.063 13.4 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein YcgR MBG_2 PF18676.1 KIK55798.1 - 0.067 13.8 3.2 0.13 12.9 3.2 1.5 1 1 0 1 1 1 0 MBG domain (YGX type) Tmem26 PF09772.9 KIK55799.1 - 0.015 14.7 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 26 Nop14 PF04147.12 KIK55800.1 - 1.1 7.3 7.0 2.2 6.4 7.0 1.4 1 0 0 1 1 1 0 Nop14-like family CCDC106 PF15794.5 KIK55800.1 - 2.1 8.0 5.6 0.5 10.1 1.7 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 FB_lectin PF07367.11 KIK55803.1 - 2.6e-51 173.3 1.5 2.9e-51 173.1 1.5 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin Sde2_N_Ubi PF13019.6 KIK55803.1 - 0.043 13.7 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain YcgR_2 PF12945.7 KIK55804.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein YcgR MBG_2 PF18676.1 KIK55806.1 - 0.15 12.8 2.2 0.29 11.8 2.2 1.5 1 1 0 1 1 1 0 MBG domain (YGX type) Integrase_H2C2 PF17921.1 KIK55812.1 - 0.025 14.7 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Integrase zinc binding domain SnoaL_2 PF12680.7 KIK55812.1 - 0.055 14.1 0.3 0.069 13.8 0.3 1.2 1 0 0 1 1 1 0 SnoaL-like domain RT_RNaseH_2 PF17919.1 KIK55813.1 - 9.5e-07 28.8 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK55813.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Latarcin PF10279.9 KIK55815.1 - 8.4 6.9 8.7 17 5.9 8.7 1.5 1 0 0 1 1 1 0 Latarcin precursor Retrotrans_gag PF03732.17 KIK55816.1 - 0.0011 19.2 2.2 0.0013 19.0 0.6 1.9 2 1 0 2 2 2 1 Retrotransposon gag protein AAA_assoc_2 PF16193.5 KIK55816.1 - 0.39 11.1 2.7 2.4 8.5 0.7 2.9 2 1 0 2 2 2 0 AAA C-terminal domain Treslin_N PF15292.6 KIK55817.1 - 0.24 9.7 0.1 0.3 9.4 0.1 1.1 1 0 0 1 1 1 0 Treslin N-terminus Tyrosinase PF00264.20 KIK55819.1 - 4.8e-16 59.7 4.2 8.8e-16 58.9 4.2 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_61 PF03443.14 KIK55820.1 - 1.1e-41 143.1 0.1 1.1e-41 143.1 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Apt1 PF10351.9 KIK55820.1 - 2.6 6.8 8.8 3.3 6.4 8.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF872 PF05915.12 KIK55821.1 - 2.2 8.5 6.6 3.8 7.7 3.3 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) NAD_binding_10 PF13460.6 KIK55822.1 - 2.7e-08 33.9 0.0 6e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIK55822.1 - 1.6e-06 27.8 0.0 0.034 13.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK55822.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KIK55822.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIK55822.1 - 0.19 10.8 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein MFS_1 PF07690.16 KIK55823.1 - 7.5e-25 87.6 19.3 9e-20 70.9 13.4 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KIK55823.1 - 9.9e-06 24.1 1.6 2.1e-05 23.0 1.6 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SlyX PF04102.12 KIK55824.1 - 5.2e-06 27.0 0.2 0.1 13.2 0.1 3.0 2 0 0 2 2 2 2 SlyX EAV_GS PF01309.18 KIK55824.1 - 0.016 14.8 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein YabA PF06156.13 KIK55824.1 - 0.03 14.9 0.2 15 6.3 0.1 2.8 2 0 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 KIK55824.1 - 0.056 14.0 3.1 1.3 9.6 0.8 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-UDP PF14569.6 KIK55824.1 - 0.097 12.8 0.0 26 5.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF4530 PF15039.6 KIK55824.1 - 0.11 12.6 4.5 5.3 7.2 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4530) CENP-F_leu_zip PF10473.9 KIK55824.1 - 0.88 9.6 17.9 0.13 12.2 0.4 3.7 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 KIK55824.1 - 2.9 8.6 9.0 11 6.7 2.0 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 KIK55824.1 - 7.5 6.7 19.7 3.6 7.8 4.2 3.3 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF816 PF05674.12 KIK55825.1 - 0.21 11.5 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) NRDE-2 PF08424.10 KIK55828.1 - 0.061 12.4 0.2 0.069 12.3 0.2 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference CRR7 PF12095.8 KIK55830.1 - 0.039 14.4 0.0 6 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 ATG16 PF08614.11 KIK55830.1 - 0.93 9.7 12.0 0.13 12.5 1.3 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KIK55832.1 - 0.00077 19.5 4.3 0.0015 18.6 4.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 KIK55832.1 - 0.00088 19.1 0.4 0.0018 18.1 0.4 1.5 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KIK55832.1 - 0.0036 17.9 0.0 0.0074 16.9 0.0 1.5 1 1 0 1 1 1 1 Initiation control protein YabA UPF0242 PF06785.11 KIK55832.1 - 0.006 16.7 1.1 0.01 16.0 1.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KIK55832.1 - 0.0069 16.9 5.5 0.0069 16.9 5.5 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF4404 PF14357.6 KIK55832.1 - 0.0094 16.6 4.0 0.029 15.0 3.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4404) Atg14 PF10186.9 KIK55832.1 - 0.0097 15.0 0.4 0.013 14.6 0.4 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Lzipper-MIP1 PF14389.6 KIK55832.1 - 0.02 15.2 2.6 0.035 14.4 2.6 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.6 KIK55832.1 - 0.021 14.2 0.5 0.042 13.2 0.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FH2 PF02181.23 KIK55832.1 - 0.039 13.1 0.4 0.057 12.5 0.4 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain MYO10_CC PF16735.5 KIK55832.1 - 0.039 14.0 2.0 0.65 10.1 0.1 2.4 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain DUF3450 PF11932.8 KIK55832.1 - 0.054 12.8 3.3 0.079 12.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DBINO PF13892.6 KIK55832.1 - 0.057 13.8 0.3 0.083 13.3 0.3 1.2 1 0 0 1 1 1 0 DNA-binding domain Spc7 PF08317.11 KIK55832.1 - 0.057 12.3 3.0 0.093 11.6 3.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 KIK55832.1 - 0.063 13.9 2.6 0.1 13.2 2.6 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 KIK55832.1 - 0.074 13.7 4.1 0.16 12.6 4.1 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fungal_TACC PF12709.7 KIK55832.1 - 0.074 13.5 0.2 0.18 12.3 0.0 1.7 2 0 0 2 2 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins ABC_tran_CTD PF16326.5 KIK55832.1 - 0.33 11.2 4.8 0.75 10.1 4.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain ATG16 PF08614.11 KIK55832.1 - 0.48 10.6 10.1 0.076 13.2 6.1 1.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 KIK55832.1 - 0.53 8.8 3.0 0.7 8.4 3.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cep57_CLD_2 PF14197.6 KIK55832.1 - 0.55 10.4 7.7 0.51 10.5 1.8 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 KIK55832.1 - 0.73 10.3 6.4 1.8 9.0 2.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Uso1_p115_C PF04871.13 KIK55832.1 - 1.5 9.2 8.9 0.17 12.2 4.3 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 KIK55832.1 - 1.9 9.2 3.9 2.8 8.6 0.9 2.2 1 1 0 2 2 2 0 SlyX DUF1295 PF06966.12 KIK55833.1 - 4.4e-14 52.6 0.1 5.9e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KIK55833.1 - 0.00015 21.8 0.1 0.00019 21.5 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KIK55833.1 - 0.00018 20.4 0.3 0.00026 19.9 0.3 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4748 PF15932.5 KIK55833.1 - 0.32 10.8 4.2 0.12 12.2 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) COMMD1_N PF17221.3 KIK55834.1 - 0.038 14.3 0.1 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 COMMD1 N-terminal domain Bacillus_HBL PF05791.11 KIK55834.1 - 0.15 11.9 1.2 0.29 10.9 1.2 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 KIK55834.1 - 0.16 12.4 5.5 0.4 11.1 5.5 1.7 1 1 0 1 1 1 0 Fez1 RicinB_lectin_2 PF14200.6 KIK55836.1 - 3.6e-18 66.1 16.8 2.1e-08 34.8 0.5 2.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK55836.1 - 0.002 18.3 0.1 0.013 15.7 0.1 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain BcrAD_BadFG PF01869.20 KIK55836.1 - 0.019 14.5 0.1 0.022 14.3 0.1 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF4231 PF14015.6 KIK55837.1 - 1.4 9.4 3.8 0.8 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HlyIII PF03006.20 KIK55838.1 - 1.6e-48 165.4 24.3 2e-48 165.1 24.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related YcxB PF14317.6 KIK55838.1 - 0.046 13.4 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 YcxB-like protein ColG_sub PF18496.1 KIK55838.1 - 0.11 12.7 0.3 0.16 12.2 0.3 1.2 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Exo_endo_phos PF03372.23 KIK55840.1 - 8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40_like PF17005.5 KIK55840.1 - 0.015 14.6 0.2 0.43 9.8 0.1 2.2 2 0 0 2 2 2 0 WD40-like domain UbiA PF01040.18 KIK55841.1 - 1e-22 80.6 15.4 1.4e-22 80.2 15.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family PetG PF02529.15 KIK55841.1 - 0.23 11.3 1.7 0.5 10.2 0.8 2.0 1 1 0 1 1 1 0 Cytochrome B6-F complex subunit 5 p450 PF00067.22 KIK55842.1 - 8.8e-56 189.6 0.0 1.1e-55 189.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribo_biogen_C PF04034.13 KIK55842.1 - 0.0048 16.6 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein, C-terminal DUF1295 PF06966.12 KIK55843.1 - 1.8e-13 50.5 0.1 2.5e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KIK55843.1 - 2e-05 23.5 1.5 3.5e-05 22.8 1.5 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KIK55843.1 - 0.0038 17.2 0.6 0.005 16.8 0.6 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase zf-H2C2_2 PF13465.6 KIK55844.1 - 0.024 15.0 0.9 0.024 15.0 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK55844.1 - 1.2 10.1 11.3 1.6 9.8 4.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF327 PF03885.13 KIK55847.1 - 0.011 15.7 1.1 0.02 14.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) TSNAXIP1_N PF15739.5 KIK55847.1 - 0.017 15.5 2.8 0.032 14.6 2.8 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF648 PF04890.13 KIK55847.1 - 0.042 13.6 0.8 0.058 13.1 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) HAD_SAK_1 PF10307.9 KIK55847.1 - 0.094 12.5 0.5 0.15 11.9 0.5 1.2 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins FAM76 PF16046.5 KIK55848.1 - 0.038 13.4 2.8 0.055 12.8 2.8 1.2 1 0 0 1 1 1 0 FAM76 protein OmpH PF03938.14 KIK55848.1 - 3.3 8.1 7.9 7 7.0 7.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Csm1_N PF18504.1 KIK55848.1 - 3.6 8.0 9.2 1.5 9.2 0.6 3.1 3 1 1 4 4 4 0 Csm1 N-terminal domain CobW_C PF07683.14 KIK55850.1 - 0.12 12.3 0.7 0.33 10.9 0.4 1.8 1 1 1 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Phage_holin_3_3 PF16083.5 KIK55855.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III ABC2_membrane_2 PF12679.7 KIK55855.1 - 1.7 7.9 6.8 4 6.6 6.8 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein PepSY_TM_like_2 PF16357.5 KIK55857.1 - 0.38 10.7 4.6 0.46 10.4 4.6 1.0 1 0 0 1 1 1 0 Putative PepSY_TM-like Rhomboid PF01694.22 KIK55858.1 - 4.6e-10 39.7 0.5 7.2e-10 39.0 0.5 1.3 1 0 0 1 1 1 1 Rhomboid family Ytp1 PF10355.9 KIK55858.1 - 1.1 8.4 4.4 1.7 7.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) Rhomboid PF01694.22 KIK55862.1 - 7.7e-31 107.1 13.0 7.7e-31 107.1 13.0 2.0 3 0 0 3 3 3 1 Rhomboid family Wzy_C PF04932.15 KIK55866.1 - 0.28 10.8 2.7 0.38 10.4 2.7 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF713 PF05218.14 KIK55869.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Abhydrolase_6 PF12697.7 KIK55870.1 - 4.4e-10 40.5 0.0 5.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK55870.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Mid2 PF04478.12 KIK55874.1 - 0.0054 16.6 0.1 0.0054 16.6 0.1 1.7 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KIK55874.1 - 0.045 13.2 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4064 PF13273.6 KIK55874.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF475 PF04332.15 KIK55875.1 - 0.0019 18.0 1.3 0.0032 17.3 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF475) DUF1461 PF07314.11 KIK55875.1 - 2.9 7.8 12.5 0.24 11.3 1.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1461) p450 PF00067.22 KIK55877.1 - 3.4e-65 220.6 0.0 3.9e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Linker_histone PF00538.19 KIK55878.1 - 0.029 14.7 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 linker histone H1 and H5 family Mid2 PF04478.12 KIK55879.1 - 0.008 16.0 0.2 0.008 16.0 0.2 2.1 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KIK55879.1 - 0.056 12.9 0.1 0.056 12.9 0.1 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain YajC PF02699.15 KIK55879.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF5305 PF17231.2 KIK55879.1 - 0.43 9.9 1.5 0.7 9.3 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BA14K PF07886.11 KIK55880.1 - 0.036 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 BA14K-like protein DUF1373 PF07117.11 KIK55880.1 - 0.04 13.9 0.9 0.057 13.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Rota_NS6 PF04866.12 KIK55882.1 - 0.036 14.3 0.2 0.06 13.6 0.2 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 DUF809 PF05663.11 KIK55883.1 - 0.033 14.3 1.0 0.038 14.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Dimer_Tnp_hAT PF05699.14 KIK55890.1 - 2.1e-09 37.0 0.0 2.4e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SLD3 PF08639.10 KIK55890.1 - 0.075 11.8 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Helitron_like_N PF14214.6 KIK55894.1 - 3.3e-17 63.3 0.0 3.6e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RNR_N PF08343.10 KIK55896.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal ELF PF03317.13 KIK55896.1 - 0.12 12.4 0.2 0.38 10.8 0.1 1.9 2 0 0 2 2 2 0 ELF protein KDZ PF18758.1 KIK55897.1 - 5.7e-20 71.9 0.0 1.4e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HTH_24 PF13412.6 KIK55902.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1373 PF07117.11 KIK55904.1 - 0.051 13.6 0.5 0.061 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Glyco_hydro_47 PF01532.20 KIK55904.1 - 0.092 11.6 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 Aminotran_1_2 PF00155.21 KIK55904.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Mid2 PF04478.12 KIK55905.1 - 0.0013 18.6 0.3 0.0013 18.6 0.3 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF456 PF04306.13 KIK55905.1 - 0.0067 16.7 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) FixQ PF05545.11 KIK55905.1 - 0.35 10.9 0.5 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Apt1 PF10351.9 KIK55905.1 - 0.46 9.3 3.8 0.61 8.9 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KIK55905.1 - 8.7 5.4 25.9 18 4.4 25.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein KDZ PF18758.1 KIK55911.1 - 2e-11 44.0 0.2 2e-11 43.9 0.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CDC4_D PF16856.5 KIK55911.1 - 0.027 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain MARVEL PF01284.23 KIK55912.1 - 0.013 15.6 9.3 0.019 15.0 9.3 1.3 1 1 0 1 1 1 0 Membrane-associating domain E1_dh PF00676.20 KIK55913.1 - 0.029 13.3 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component Mid2 PF04478.12 KIK55914.1 - 0.0061 16.4 1.1 0.0074 16.1 1.1 1.0 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3852 PF12963.7 KIK55914.1 - 0.036 14.4 0.2 0.045 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) TrbC PF04956.13 KIK55914.1 - 0.078 13.2 2.2 0.13 12.5 2.2 1.3 1 1 0 1 1 1 0 TrbC/VIRB2 family DUF5455 PF17537.2 KIK55914.1 - 0.16 12.4 1.7 0.2 12.1 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) Mid2 PF04478.12 KIK55917.1 - 0.005 16.7 0.1 0.005 16.7 0.1 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF456 PF04306.13 KIK55917.1 - 0.021 15.1 0.2 0.035 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SKG6 PF08693.10 KIK55917.1 - 0.035 13.5 0.2 0.11 12.0 0.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FlgH PF02107.16 KIK55917.1 - 0.048 13.3 9.7 0.08 12.6 9.7 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein PMP1_2 PF08114.11 KIK55917.1 - 0.18 11.6 0.3 0.33 10.7 0.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family stn_TNFRSF12A PF12191.8 KIK55917.1 - 0.29 11.3 3.1 0.23 11.7 0.2 2.2 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Apt1 PF10351.9 KIK55917.1 - 0.86 8.4 6.2 1.2 7.9 6.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain LapA_dom PF06305.11 KIK55917.1 - 4.8 7.1 4.9 1.9 8.4 0.6 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Helitron_like_N PF14214.6 KIK55918.1 - 6.2e-05 23.3 0.0 6.7e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 KIK55920.1 - 1.6e-09 37.7 0.0 3.9e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK55920.1 - 7.3e-06 25.4 0.1 4.6e-05 22.8 0.1 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KIK55920.1 - 0.00015 22.1 0.0 0.00068 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain NOP5NT PF08156.13 KIK55920.1 - 0.015 15.7 0.3 0.04 14.3 0.3 1.7 1 0 0 1 1 1 0 NOP5NT (NUC127) domain AAA_29 PF13555.6 KIK55920.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KIK55920.1 - 0.095 11.7 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KIK55920.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TetR_N PF00440.23 KIK55921.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Mid2 PF04478.12 KIK55926.1 - 0.003 17.4 0.2 0.003 17.4 0.2 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.10 KIK55926.1 - 0.035 12.8 4.0 0.052 12.2 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KIK55926.1 - 0.48 9.2 3.9 0.58 8.9 3.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KIK55926.1 - 0.52 10.2 9.3 0.77 9.6 9.3 1.2 1 0 0 1 1 1 0 SPX domain LapA_dom PF06305.11 KIK55926.1 - 0.78 9.6 5.9 5.7 6.8 0.2 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1631 PF07793.11 KIK55926.1 - 5.4 5.3 5.6 7.7 4.8 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF5613 PF18467.1 KIK55927.1 - 0.053 13.9 0.1 0.19 12.1 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5613) DUF4767 PF15983.5 KIK55929.1 - 0.098 12.9 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) Glyco_transf_15 PF01793.16 KIK55930.1 - 3.2e-17 62.8 1.4 4.1e-17 62.4 1.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ndc1_Nup PF09531.10 KIK55931.1 - 0.0059 15.4 4.5 0.0069 15.1 4.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KIK55931.1 - 0.59 10.0 11.4 0.74 9.7 11.4 1.2 1 0 0 1 1 1 0 SPX domain stn_TNFRSF12A PF12191.8 KIK55931.1 - 6 7.1 6.3 1.1 9.4 0.1 2.7 2 1 1 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Epimerase PF01370.21 KIK55934.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gly-zipper_Omp PF13488.6 KIK55935.1 - 0.00064 19.7 0.7 0.0019 18.1 0.7 1.7 1 0 0 1 1 1 1 Glycine zipper PMP1_2 PF08114.11 KIK55935.1 - 0.0012 18.5 0.4 0.0024 17.6 0.4 1.4 1 0 0 1 1 1 1 ATPase proteolipid family Rick_17kDa_Anti PF05433.15 KIK55935.1 - 0.0094 15.8 0.7 0.023 14.6 0.7 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF2207 PF09972.9 KIK55935.1 - 0.0099 14.7 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 KIK55935.1 - 0.017 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KIK55935.1 - 0.048 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KIK55935.1 - 0.053 12.9 0.4 0.11 11.9 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Romo1 PF10247.9 KIK55935.1 - 0.054 13.9 1.5 0.16 12.3 0.2 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Mid2 PF04478.12 KIK55935.1 - 0.078 12.8 8.7 0.024 14.5 5.0 2.0 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor DUF2062 PF09835.9 KIK55935.1 - 0.13 12.1 0.3 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) FeoB_associated PF12669.7 KIK55935.1 - 0.14 12.6 0.3 0.23 11.9 0.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TMEM154 PF15102.6 KIK55935.1 - 1.5 8.7 7.7 18 5.2 7.7 2.5 1 1 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 KIK55935.1 - 2.8 6.7 4.0 2.7 6.7 1.6 1.7 1 1 1 2 2 2 0 Amnionless Beta-APP PF03494.13 KIK55935.1 - 9.1 6.2 8.1 0.62 10.0 2.8 1.7 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Glyco_transf_15 PF01793.16 KIK55936.1 - 2.2e-116 388.7 5.7 4.9e-116 387.5 5.7 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mid2 PF04478.12 KIK55937.1 - 0.0001 22.2 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF456 PF04306.13 KIK55937.1 - 0.0077 16.5 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) YajC PF02699.15 KIK55937.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit TMEM154 PF15102.6 KIK55937.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EPO_TPO PF00758.18 KIK55938.1 - 0.028 14.4 0.5 0.028 14.4 0.5 1.7 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin Pdase_C33_assoc PF14756.6 KIK55938.1 - 0.14 12.1 0.9 0.2 11.6 0.9 1.4 1 1 0 1 1 1 0 Peptidase_C33-associated domain Mid2 PF04478.12 KIK55943.1 - 0.0021 17.9 0.5 0.0041 17.0 0.5 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor PMP1_2 PF08114.11 KIK55943.1 - 0.025 14.3 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 ATPase proteolipid family SKG6 PF08693.10 KIK55943.1 - 0.084 12.3 0.6 0.21 11.0 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YajC PF02699.15 KIK55943.1 - 0.16 11.9 0.1 0.54 10.2 0.0 1.9 1 1 1 2 2 2 0 Preprotein translocase subunit LapA_dom PF06305.11 KIK55943.1 - 0.43 10.4 3.9 45 4.0 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 KIK55943.1 - 2.4 8.0 10.1 69 3.3 10.1 2.2 1 1 0 1 1 1 0 TMEM154 protein family SHE3 PF17078.5 KIK55944.1 - 0.06 13.1 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 PMP1_2 PF08114.11 KIK55946.1 - 0.0022 17.7 0.2 0.0043 16.8 0.2 1.4 1 0 0 1 1 1 1 ATPase proteolipid family SKG6 PF08693.10 KIK55946.1 - 0.0064 15.9 1.1 0.012 15.0 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KIK55946.1 - 0.059 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Mucin15 PF15672.5 KIK55946.1 - 0.072 12.6 6.4 0.1 12.0 6.4 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Gly-zipper_Omp PF13488.6 KIK55946.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.7 3 0 0 3 3 3 0 Glycine zipper FeoB_associated PF12669.7 KIK55946.1 - 0.17 12.3 0.2 0.34 11.3 0.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Glyco_transf_15 PF01793.16 KIK55947.1 - 6.6e-36 124.2 1.0 7.3e-36 124.1 1.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Cu_amine_oxidN1 PF07833.11 KIK55948.1 - 0.16 12.4 5.5 13 6.3 0.3 3.1 1 1 3 4 4 4 0 Copper amine oxidase N-terminal domain DUF3018 PF11455.8 KIK55948.1 - 7 6.7 7.6 21 5.1 0.3 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3018) DUF1651 PF07864.11 KIK55949.1 - 0.14 12.6 0.2 38 4.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) SNF2_N PF00176.23 KIK55950.1 - 3.2e-20 72.2 0.6 5.2e-20 71.5 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK55950.1 - 4.4e-13 49.6 0.3 1.3e-12 48.0 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK55950.1 - 1.6e-08 34.1 0.1 2.9e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-H2C2_2 PF13465.6 KIK55951.1 - 0.00058 20.2 0.3 0.00058 20.2 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK55951.1 - 0.15 12.5 4.5 0.5 10.9 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK55951.1 - 0.17 12.8 4.4 1.9 9.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PknG_rubred PF16919.5 KIK55954.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain DHHC PF01529.20 KIK55955.1 - 1.8 8.6 9.9 12 6.0 9.7 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase FtsX PF02687.21 KIK55955.1 - 5.8 7.4 10.5 0.47 11.0 0.8 2.5 2 1 0 2 2 2 0 FtsX-like permease family DUF3552 PF12072.8 KIK55956.1 - 5.7e-07 29.1 23.6 5.7e-07 29.1 23.6 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 KIK55956.1 - 0.14 11.7 18.9 0.045 13.3 16.3 1.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit ALMT PF11744.8 KIK55956.1 - 0.24 10.2 16.2 0.35 9.7 16.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 KIK55956.1 - 0.58 8.9 12.6 0.85 8.3 12.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.6 KIK55956.1 - 1.2 9.1 18.3 3.9 7.4 18.3 1.7 1 1 0 1 1 1 0 Protein Family FAM60A Zip PF02535.22 KIK55956.1 - 2.1 7.5 5.8 3 7.0 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter XRN_M PF17846.1 KIK55956.1 - 7.9 5.3 13.0 11 4.8 13.0 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF5635 PF18685.1 KIK55957.1 - 0.087 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Myb_DNA-binding PF00249.31 KIK55959.1 - 4.9e-38 129.1 7.7 7.3e-14 51.7 0.4 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK55959.1 - 4.7e-28 97.2 1.1 1.1e-13 51.2 0.3 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIK55959.1 - 0.00018 21.4 0.3 0.12 12.2 0.0 3.1 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KIK55959.1 - 0.00021 21.3 0.0 5 7.2 0.0 3.2 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_2 PF08914.11 KIK55959.1 - 0.00039 20.5 0.0 2.5 8.3 0.0 3.2 3 0 0 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 KIK55959.1 - 0.0033 17.5 1.0 1.1 9.3 0.1 2.9 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 KIK55959.1 - 0.004 17.3 1.3 0.18 12.0 0.0 2.8 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 KIK55959.1 - 0.015 15.6 1.4 5.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GMC_oxred_N PF00732.19 KIK55960.1 - 8.6e-44 150.1 0.0 1.2e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK55960.1 - 8.2e-28 97.7 0.0 1.4e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Transp_cyt_pur PF02133.15 KIK55962.1 - 1.3e-29 103.3 37.5 3.1e-29 102.0 37.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PsbT PF01405.17 KIK55962.1 - 0.41 10.5 0.1 0.41 10.5 0.1 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre T protein PPP5 PF08321.12 KIK55963.1 - 0.092 13.1 0.0 0.11 12.8 0.0 1.3 1 1 0 1 1 1 0 PPP5 TPR repeat region Abhydrolase_6 PF12697.7 KIK55964.1 - 1.1e-12 49.1 0.0 1.4e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amnionless PF14828.6 KIK55966.1 - 0.002 17.0 0.3 0.0027 16.6 0.3 1.1 1 0 0 1 1 1 1 Amnionless TMEM51 PF15345.6 KIK55966.1 - 0.04 13.8 0.6 0.073 12.9 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 KIK55966.1 - 0.042 14.7 0.3 0.15 13.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Kisspeptin PF15152.6 KIK55966.1 - 2.5 8.9 5.9 4.8 8.0 0.1 2.9 3 1 0 3 3 3 0 Kisspeptin Amnionless PF14828.6 KIK55967.1 - 0.0059 15.5 0.1 0.0082 15.0 0.1 1.1 1 0 0 1 1 1 1 Amnionless TMEM154 PF15102.6 KIK55967.1 - 0.14 12.1 0.2 0.14 12.1 0.2 1.9 2 0 0 2 2 2 0 TMEM154 protein family CcmD PF04995.14 KIK55967.1 - 0.16 12.0 1.6 0.33 11.1 1.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 KIK55967.1 - 0.18 12.7 0.0 0.36 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECF_trnsprt PF12822.7 KIK55968.1 - 0.0059 16.7 0.2 0.0079 16.3 0.2 1.3 1 0 0 1 1 1 1 ECF transporter, substrate-specific component TRPM_tetra PF16519.5 KIK55968.1 - 0.042 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Gram_pos_anchor PF00746.21 KIK55968.1 - 0.19 11.7 0.3 0.36 10.8 0.3 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cytomega_TRL10 PF06084.11 KIK55968.1 - 0.2 11.7 0.1 0.35 10.9 0.1 1.4 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein TMEM154 PF15102.6 KIK55970.1 - 0.04 13.8 0.6 0.069 13.1 0.3 1.6 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KIK55970.1 - 0.095 13.6 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KIK55970.1 - 0.2 11.6 0.3 0.34 10.9 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 KIK55970.1 - 0.23 10.2 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless LVIVD PF08309.11 KIK55972.1 - 0.12 11.7 0.1 0.32 10.4 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat SKG6 PF08693.10 KIK55972.1 - 2 7.9 5.2 7.1 6.1 5.2 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 KIK55975.1 - 3.2e-32 111.6 0.2 6e-32 110.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK55975.1 - 5.8e-08 32.7 13.2 5.8e-08 32.7 13.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc24 PF08286.11 KIK55975.1 - 0.057 13.7 0.3 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HrpB7 PF09486.10 KIK55975.1 - 0.11 12.9 5.7 0.56 10.6 5.7 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FRG2 PF15315.6 KIK55975.1 - 1.1 9.4 4.0 3.4 7.8 4.0 1.8 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 GMC_oxred_N PF00732.19 KIK55976.1 - 1.4e-55 188.8 0.0 1.9e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK55976.1 - 4.3e-32 111.6 0.0 6.6e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KIK55976.1 - 1.5e-05 24.7 0.5 7.9e-05 22.4 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK55976.1 - 2.8e-05 23.5 0.0 0.00083 18.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK55976.1 - 0.00021 20.5 0.4 0.013 14.6 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK55976.1 - 0.00041 20.5 0.1 0.0018 18.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FPN1 PF06963.12 KIK55976.1 - 0.008 14.8 0.7 0.012 14.3 0.7 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) FAD_binding_3 PF01494.19 KIK55976.1 - 0.011 15.0 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK55976.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK55976.1 - 0.017 14.1 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KIK55976.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KIK55976.1 - 0.19 10.4 0.3 0.35 9.5 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein DUF2794 PF10984.8 KIK55976.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) Trp_halogenase PF04820.14 KIK55976.1 - 0.23 10.3 0.2 0.33 9.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RsmJ PF04378.13 KIK55979.1 - 0.024 13.8 0.1 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ GMC_oxred_N PF00732.19 KIK55980.1 - 6.7e-53 180.0 0.0 8.6e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK55980.1 - 2.8e-32 112.2 0.0 4.7e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KIK55980.1 - 3.6e-07 30.1 0.1 8.9e-07 28.8 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK55980.1 - 2.5e-05 23.5 0.1 0.0026 16.9 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK55980.1 - 0.00023 21.3 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK55980.1 - 0.00032 20.0 0.0 0.003 16.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK55980.1 - 0.0088 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK55980.1 - 0.012 14.9 0.0 0.072 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK55980.1 - 0.024 13.9 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FPN1 PF06963.12 KIK55980.1 - 0.071 11.7 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Trp_halogenase PF04820.14 KIK55980.1 - 0.13 11.1 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KIK55980.1 - 0.14 10.9 0.1 0.25 10.0 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein WBP-1 PF11669.8 KIK55981.1 - 0.13 12.9 0.1 0.54 10.9 0.0 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 RCR PF12273.8 KIK55981.1 - 1.4 9.6 5.4 1.4 9.6 0.5 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1180 PF06679.12 KIK55981.1 - 2.4 8.5 7.4 0.49 10.8 2.6 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) Shisa PF13908.6 KIK55981.1 - 8.4 6.6 8.6 0.56 10.4 0.4 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator UbiA PF01040.18 KIK55982.1 - 1.2e-18 67.3 5.8 1.5e-18 67.0 5.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PrgI PF12666.7 KIK55982.1 - 0.49 11.1 4.1 0.53 11.0 0.1 2.5 2 1 0 2 2 2 0 PrgI family protein Herpes_gE PF02480.16 KIK55983.1 - 0.024 13.4 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK55983.1 - 0.032 15.1 0.0 0.055 14.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KIK55983.1 - 0.037 13.4 1.3 0.11 11.9 1.3 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KIK55983.1 - 0.08 12.7 0.8 0.16 11.8 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Hum_adeno_E3A PF05393.11 KIK55983.1 - 0.085 12.8 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein CHS5_N PF16892.5 KIK55983.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.4 3 0 0 3 3 3 0 Chitin biosynthesis protein CHS5 N-terminus Amnionless PF14828.6 KIK55983.1 - 0.22 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless SPX PF03105.19 KIK55983.1 - 0.22 11.4 1.8 0.25 11.2 1.8 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KIK55983.1 - 4.5 6.4 12.4 6.7 5.8 12.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Shisa PF13908.6 KIK55983.1 - 7.3 6.8 9.5 0.4 10.9 0.4 2.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator ABC2_membrane_3 PF12698.7 KIK55984.1 - 0.041 13.0 0.1 0.068 12.3 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Hum_adeno_E3A PF05393.11 KIK55984.1 - 0.082 12.9 0.1 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Herpes_gE PF02480.16 KIK55984.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK55984.1 - 0.13 13.1 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CHS5_N PF16892.5 KIK55984.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.1 3 0 0 3 3 3 0 Chitin biosynthesis protein CHS5 N-terminus SPX PF03105.19 KIK55984.1 - 0.4 10.6 4.4 0.46 10.3 4.4 1.2 1 0 0 1 1 1 0 SPX domain PIG-P PF08510.12 KIK55985.1 - 0.082 12.8 2.9 0.11 12.5 2.9 1.2 1 0 0 1 1 1 0 PIG-P Asp PF00026.23 KIK55986.1 - 1.6e-80 270.9 9.1 1.9e-80 270.6 9.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK55986.1 - 1.6e-13 51.3 9.7 7.3e-12 45.9 9.7 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK55986.1 - 0.019 15.6 2.6 0.15 12.7 0.7 2.9 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KIK55987.1 - 9.4e-08 31.8 0.6 1.3e-07 31.4 0.6 1.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.20 KIK55988.1 - 0.056 13.4 0.7 0.097 12.6 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain MscL PF01741.18 KIK55988.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL EphA2_TM PF14575.6 KIK55988.1 - 0.07 14.0 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK55989.1 - 0.013 14.4 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 KIK55989.1 - 0.023 13.5 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VPDSG-CTERM PF18205.1 KIK55989.1 - 0.83 9.5 3.9 4 7.4 2.2 2.5 2 0 0 2 2 2 0 VPDSG-CTERM motif GRA6 PF05084.13 KIK55989.1 - 5.1 7.0 8.9 0.73 9.8 1.3 2.2 1 1 1 2 2 2 0 Granule antigen protein (GRA6) Adeno_E3_CR2 PF02439.15 KIK55990.1 - 0.018 14.8 2.0 0.033 13.9 2.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Na_Ca_ex PF01699.24 KIK55990.1 - 0.062 13.2 6.6 0.087 12.8 6.6 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Amnionless PF14828.6 KIK55990.1 - 0.081 11.7 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 KIK55990.1 - 0.31 10.6 0.6 0.42 10.1 0.6 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 KIK55990.1 - 0.37 10.7 6.5 3.1 7.7 6.5 2.1 1 1 0 1 1 1 0 TMEM154 protein family RANK_CRD_2 PF18278.1 KIK55991.1 - 0.017 15.3 0.3 0.04 14.1 0.3 1.6 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Epimerase_2 PF02350.19 KIK55994.1 - 8.4e-65 218.9 0.0 1e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DRTGG PF07085.12 KIK55994.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 DRTGG domain Glyco_transf_15 PF01793.16 KIK55996.1 - 3.2e-40 138.4 2.2 3.7e-40 138.2 2.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KIK55996.1 - 0.19 12.0 0.4 0.22 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Glyco_transf_15 PF01793.16 KIK55998.1 - 2.5e-112 375.3 12.4 2.8e-112 375.2 12.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TMEM51 PF15345.6 KIK55999.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 KIK55999.1 - 0.004 18.0 0.0 0.0074 17.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK55999.1 - 0.0046 15.8 0.1 0.0049 15.8 0.1 1.1 1 0 0 1 1 1 1 Amnionless Stevor PF17410.2 KIK55999.1 - 0.0054 16.3 0.0 0.0075 15.8 0.0 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 KIK55999.1 - 0.0061 15.9 5.1 0.012 15.0 5.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.16 KIK55999.1 - 0.034 12.9 0.3 0.052 12.3 0.1 1.2 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Insulin_TMD PF17870.1 KIK55999.1 - 0.13 12.4 0.3 0.22 11.6 0.3 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2207 PF09972.9 KIK55999.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MGC-24 PF05283.11 KIK55999.1 - 0.18 12.2 5.5 0.32 11.4 5.5 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adeno_E3_CR2 PF02439.15 KIK55999.1 - 0.53 10.1 3.1 0.29 10.9 0.7 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 KIK55999.1 - 0.82 9.5 2.8 1.6 8.6 2.9 1.5 1 1 0 1 1 1 0 Rifin TMEM154 PF15102.6 KIK56001.1 - 0.00021 21.2 10.0 0.00021 21.2 10.0 2.5 2 1 0 2 2 2 1 TMEM154 protein family RIFIN PF02009.16 KIK56001.1 - 0.00097 19.1 0.4 0.0014 18.6 0.4 1.3 1 0 0 1 1 1 1 Rifin Amnionless PF14828.6 KIK56001.1 - 0.011 14.6 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless Apt1 PF10351.9 KIK56001.1 - 0.034 13.0 2.0 0.038 12.9 2.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SKG6 PF08693.10 KIK56001.1 - 0.039 13.4 3.3 0.096 12.1 3.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF898 PF05987.13 KIK56001.1 - 0.042 12.9 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF5305 PF17231.2 KIK56001.1 - 0.096 12.1 2.1 0.17 11.3 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 KIK56001.1 - 0.12 13.3 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 KIK56001.1 - 0.25 11.4 18.1 0.015 15.4 11.8 1.9 2 0 0 2 2 2 0 Podoplanin Macoilin PF09726.9 KIK56001.1 - 0.29 9.6 2.0 0.32 9.5 2.0 1.2 1 0 0 1 1 1 0 Macoilin family Kei1 PF08552.11 KIK56001.1 - 0.42 10.5 3.3 0.78 9.6 3.3 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1180 PF06679.12 KIK56001.1 - 0.75 10.2 13.8 0.13 12.7 9.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF908 PF06012.12 KIK56001.1 - 0.9 8.9 8.6 0.081 12.3 4.4 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Fasciclin PF02469.22 KIK56003.1 - 1.5e-06 28.5 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF1590 PF07629.11 KIK56003.1 - 0.05 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) NACHT PF05729.12 KIK56005.1 - 0.038 13.9 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Apo-VLDL-II PF05418.11 KIK56005.1 - 0.11 13.1 0.0 0.18 12.4 0.0 1.4 1 1 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) NB-ARC PF00931.22 KIK56005.1 - 0.19 10.9 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Ank_4 PF13637.6 KIK56006.1 - 3.5e-16 59.3 0.3 6e-07 29.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK56006.1 - 9.9e-12 44.8 2.6 0.002 18.5 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KIK56006.1 - 1.8e-11 44.5 0.1 3.2e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK56006.1 - 1.2e-10 40.6 0.4 0.011 16.2 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KIK56006.1 - 2.7e-07 30.7 1.1 0.00058 20.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Xpo1 PF08389.12 KIK56007.1 - 5.5e-36 123.9 5.7 5.7e-36 123.8 3.9 2.0 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIK56007.1 - 5.1e-29 99.7 4.6 1.4e-28 98.3 4.6 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIK56007.1 - 2.9e-26 91.3 2.6 3.8e-26 91.0 0.5 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIK56007.1 - 1.8e-15 56.1 5.1 1.8e-15 56.1 5.1 2.0 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat CRM1_C PF08767.11 KIK56008.1 - 2.5e-43 148.5 0.1 8.1e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 CRM1 C terminal ANTH PF07651.16 KIK56008.1 - 0.17 10.9 0.3 0.23 10.4 0.3 1.2 1 0 0 1 1 1 0 ANTH domain DUF2569 PF10754.9 KIK56012.1 - 0.0048 17.3 0.0 0.008 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) Amnionless PF14828.6 KIK56012.1 - 0.029 13.2 0.3 0.038 12.8 0.3 1.1 1 0 0 1 1 1 0 Amnionless NICE-1 PF15845.5 KIK56012.1 - 0.23 12.2 0.1 0.23 12.2 0.1 3.6 3 2 0 3 3 3 0 Cysteine-rich C-terminal 1 family Adeno_E3_CR2 PF02439.15 KIK56012.1 - 0.61 9.9 2.1 0.84 9.4 0.1 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 CRM1_repeat PF18777.1 KIK56013.1 - 5.8e-17 60.9 3.3 9.4e-17 60.2 3.3 1.4 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIK56013.1 - 0.0088 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat_2 PF18784.1 KIK56013.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 HTH_Tnp_Tc5 PF03221.16 KIK56014.1 - 2.3e-14 53.1 0.0 4.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KIK56014.1 - 8.9e-06 25.3 0.3 2.8e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KIK56014.1 - 0.018 14.8 1.5 0.025 14.4 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 KIK56014.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease DUF4296 PF14129.6 KIK56014.1 - 0.048 14.3 0.1 1.4 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) HTH_23 PF13384.6 KIK56014.1 - 0.052 13.4 0.3 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain F-box-like PF12937.7 KIK56017.1 - 0.00026 20.8 0.3 0.00077 19.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK56017.1 - 0.24 11.3 2.2 0.22 11.4 0.3 1.9 2 0 0 2 2 2 0 F-box CDP-OH_P_transf PF01066.21 KIK56019.1 - 7.4 7.4 7.1 0.9 10.4 2.4 1.8 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase DUF4218 PF13960.6 KIK56020.1 - 0.15 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 KIK56021.1 - 0.0006 19.1 0.0 0.00075 18.8 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF2145 PF09916.9 KIK56022.1 - 0.042 13.5 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) MAGI_u5 PF16666.5 KIK56024.1 - 2.9 8.0 7.1 4.8 7.3 5.1 2.1 1 1 1 2 2 2 0 Unstructured region on MAGI Herpes_LMP1 PF05297.11 KIK56025.1 - 6.2 5.9 5.7 8.5 5.5 5.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Cupin_4 PF08007.12 KIK56026.1 - 0.0041 16.6 0.9 0.0057 16.2 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein RRT14 PF17075.5 KIK56026.1 - 0.074 13.2 4.6 0.12 12.5 4.6 1.2 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 AraC_binding PF02311.19 KIK56026.1 - 0.13 12.2 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain WD40 PF00400.32 KIK56027.1 - 5.4e-05 23.9 0.3 0.0066 17.3 0.0 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56027.1 - 0.0051 17.1 0.3 0.13 12.5 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PDDEXK_10 PF07788.11 KIK56027.1 - 0.1 12.6 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Glycos_transf_1 PF00534.20 KIK56032.1 - 0.032 13.8 0.0 0.091 12.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 DMT_6 PF04342.12 KIK56035.1 - 0.16 12.2 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 Putative member of DMT superfamily (DUF486) Penicil_amidase PF01804.18 KIK56035.1 - 0.2 10.5 0.1 0.91 8.4 0.0 1.8 2 0 0 2 2 2 0 Penicillin amidase DUF3670 PF12419.8 KIK56037.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 SNF2 Helicase protein BUD22 PF09073.10 KIK56037.1 - 0.6 9.4 7.6 0.67 9.2 7.6 1.1 1 0 0 1 1 1 0 BUD22 CRM1_repeat_3 PF18787.1 KIK56038.1 - 1.9e-23 82.3 1.0 1.9e-23 82.3 1.0 2.2 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 DUF3385 PF11865.8 KIK56038.1 - 0.003 17.5 0.0 0.0092 15.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3385) IL22 PF14565.6 KIK56038.1 - 0.048 13.9 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor MarB PF13999.6 KIK56039.1 - 0.06 13.2 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 MarB protein Ank_2 PF12796.7 KIK56042.1 - 3.5e-12 46.7 0.4 1.1e-09 38.7 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK56042.1 - 2.7e-09 37.4 0.0 1.2e-05 25.7 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK56042.1 - 2.1e-08 34.3 0.4 1.2 9.8 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KIK56042.1 - 2.3e-08 33.6 0.1 2.5 9.0 0.0 6.0 6 0 0 6 6 5 2 Ankyrin repeat NACHT PF05729.12 KIK56042.1 - 3.6e-07 30.2 0.2 1.9e-06 27.9 0.2 2.1 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK56042.1 - 8.1e-05 21.9 0.3 0.00017 20.8 0.3 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK56042.1 - 0.00082 19.8 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK56042.1 - 0.0026 18.0 0.0 0.0085 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.6 KIK56042.1 - 0.011 16.1 0.2 0.84 10.0 0.0 3.9 3 1 2 5 5 4 0 Ankyrin repeats (many copies) RNA_helicase PF00910.22 KIK56042.1 - 0.024 15.0 0.0 0.072 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK56042.1 - 0.032 14.3 0.2 0.86 9.6 0.1 3.1 1 1 0 1 1 1 0 AAA domain VWA_3_C PF18571.1 KIK56042.1 - 0.046 13.6 0.4 12 5.9 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Vta1 PF04652.16 KIK56042.1 - 0.4 10.7 4.3 1.4 8.9 0.3 3.0 3 1 0 3 3 3 0 Vta1 like DUF4208 PF13907.6 KIK56042.1 - 0.5 10.8 4.0 4.9 7.7 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) MIP-T3_C PF17749.1 KIK56042.1 - 0.62 10.0 5.3 0.34 10.8 1.0 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fasciclin PF02469.22 KIK56043.1 - 0.014 15.6 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Fasciclin domain Fasciclin PF02469.22 KIK56046.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain Asp PF00026.23 KIK56047.1 - 5.3e-30 104.9 0.6 8.6e-30 104.2 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease IL22 PF14565.6 KIK56049.1 - 0.028 14.7 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor SWIRM PF04433.17 KIK56049.1 - 0.032 14.6 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 SWIRM domain CRM1_repeat_2 PF18784.1 KIK56050.1 - 4.4e-29 99.9 6.4 9.9e-29 98.8 6.4 1.6 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIK56050.1 - 9.4e-26 89.7 2.1 1.4e-25 89.1 0.6 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIK56050.1 - 8e-16 57.3 2.9 1.5e-15 56.4 2.9 1.5 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat RTP1_C2 PF10304.9 KIK56050.1 - 0.019 14.7 0.4 0.041 13.6 0.4 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 Fasciclin PF02469.22 KIK56051.1 - 0.022 15.0 0.1 0.3 11.3 0.0 2.4 2 1 1 3 3 3 0 Fasciclin domain YfhD PF14151.6 KIK56051.1 - 0.092 12.9 0.1 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 YfhD-like protein Asp PF00026.23 KIK56052.1 - 1.7e-15 57.3 1.2 4.3e-15 55.9 1.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK56052.1 - 0.0021 18.3 0.1 0.22 11.8 0.1 2.0 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DUF3403 PF11883.8 KIK56052.1 - 0.02 15.0 0.1 0.075 13.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3403) WD40 PF00400.32 KIK56055.1 - 3.1e-134 432.9 35.9 7.1e-11 42.5 0.1 14.0 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56055.1 - 8.3e-48 160.6 11.6 0.0038 17.5 0.0 13.2 1 1 11 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56055.1 - 8.3e-26 91.1 5.4 3.9e-05 23.6 0.1 5.6 1 1 2 5 5 5 5 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK56055.1 - 8.8e-20 71.2 6.3 0.18 11.1 0.1 11.0 9 3 2 11 11 11 6 WD40-like domain Nup160 PF11715.8 KIK56055.1 - 1.9e-18 66.4 14.1 0.037 12.7 0.0 10.9 5 4 6 11 11 11 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK56055.1 - 1.8e-10 40.3 8.6 6.1 5.7 0.0 10.3 3 2 8 12 12 12 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK56055.1 - 2.1e-08 33.9 0.4 39 4.3 0.0 9.8 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat potato_inhibit PF00280.18 KIK56055.1 - 3.4e-07 30.8 5.6 3.8 8.2 0.0 8.7 7 2 2 9 9 9 1 Potato inhibitor I family NACHT PF05729.12 KIK56055.1 - 7.8e-07 29.2 0.3 2.4e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 NACHT domain NHL PF01436.21 KIK56055.1 - 4.6e-05 23.2 16.9 18 5.6 0.1 9.1 9 0 0 9 9 9 0 NHL repeat DsbC_N PF10411.9 KIK56055.1 - 7.8e-05 22.0 5.2 66 3.1 0.0 8.9 10 0 0 10 10 10 0 Disulfide bond isomerase protein N-terminus COPI_C PF06957.11 KIK56055.1 - 0.00035 19.4 0.0 21 3.7 0.0 5.4 4 2 0 6 6 6 0 Coatomer (COPI) alpha subunit C-terminus Peptidase_S9_N PF02897.15 KIK56055.1 - 0.00059 18.8 0.9 3.2 6.4 0.0 4.9 2 2 2 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain APS_kinase PF01583.20 KIK56055.1 - 0.00083 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase nos_propeller PF18764.1 KIK56055.1 - 0.0011 18.8 22.5 16 5.5 0.0 10.3 13 0 0 13 13 13 0 Nitrous oxide reductase propeller repeat AAA_16 PF13191.6 KIK56055.1 - 0.0017 18.8 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK56055.1 - 0.029 14.9 0.2 0.2 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK56055.1 - 0.05 14.0 0.2 5.8 7.4 0.0 3.3 3 1 1 4 4 3 0 RNA helicase ATPase_2 PF01637.18 KIK56055.1 - 0.076 12.9 0.2 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DDE_1 PF03184.19 KIK56056.1 - 6.8e-05 22.6 0.0 7.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sushi_2 PF09014.10 KIK56056.1 - 0.052 13.4 0.3 0.065 13.1 0.3 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Bac_rhamnosid_N PF08531.10 KIK56057.1 - 0.01 15.7 0.2 0.075 12.8 0.0 2.3 2 1 1 3 3 3 0 Alpha-L-rhamnosidase N-terminal domain BetaGal_dom4_5 PF13364.6 KIK56057.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Glyco_hydro_2_N PF02837.18 KIK56057.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain NAD_binding_8 PF13450.6 KIK56058.1 - 1.9e-10 40.8 0.0 1.1e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK56058.1 - 2.2e-10 40.4 0.0 7.7e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KIK56058.1 - 5.3e-05 22.1 0.0 8.7e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KIK56058.1 - 9.2e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK56058.1 - 9.9e-05 22.1 0.0 0.0002 21.1 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK56058.1 - 0.0024 17.2 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK56058.1 - 0.0033 16.7 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIK56058.1 - 0.0033 16.6 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK56058.1 - 0.0051 16.1 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK56058.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK56058.1 - 0.038 14.5 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIK56058.1 - 0.041 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KIK56058.1 - 0.056 13.4 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK56058.1 - 0.2 10.7 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein BTB PF00651.31 KIK56059.1 - 0.00071 19.8 0.0 0.0017 18.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Dynamin_N PF00350.23 KIK56061.1 - 2.1e-16 60.4 0.3 9.9e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KIK56061.1 - 3.5e-08 33.5 0.0 0.0027 17.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK56061.1 - 4.6e-05 23.4 0.0 0.00016 21.6 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK56061.1 - 0.00041 20.9 0.3 0.0023 18.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KIK56061.1 - 0.0018 18.7 0.0 0.0018 18.7 0.0 2.8 2 1 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KIK56061.1 - 0.0046 16.3 0.0 0.016 14.5 0.0 1.9 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KIK56061.1 - 0.0061 16.8 0.0 0.05 13.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK56061.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KIK56061.1 - 0.016 14.3 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) CPT PF07931.12 KIK56061.1 - 0.02 14.7 0.2 3 7.7 0.0 2.8 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 KIK56061.1 - 0.051 14.1 0.0 0.051 14.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain G-alpha PF00503.20 KIK56061.1 - 9.8 5.2 9.2 23 4.0 4.9 3.3 2 1 0 2 2 2 0 G-protein alpha subunit Ldh_1_N PF00056.23 KIK56062.1 - 5e-47 159.6 0.1 7.9e-47 158.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KIK56062.1 - 5.9e-43 146.7 0.0 8.3e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KIK56062.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KIK56062.1 - 0.048 13.0 2.1 1.1 8.6 0.2 3.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Hepar_II_III PF07940.13 KIK56064.1 - 2.1e-07 30.8 0.2 3.7e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein Lon_C PF05362.13 KIK56065.1 - 1.1e-57 195.0 0.1 1.9e-57 194.1 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KIK56065.1 - 9.3e-21 74.6 0.0 4.8e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK56065.1 - 6.7e-11 42.3 0.0 1.9e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KIK56065.1 - 2.8e-06 27.2 0.0 7.8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KIK56065.1 - 0.00017 22.0 3.4 0.00057 20.3 0.2 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KIK56065.1 - 0.00022 21.4 0.0 0.00069 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIK56065.1 - 0.004 17.3 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK56065.1 - 0.0045 16.7 0.1 0.045 13.5 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KIK56065.1 - 0.02 14.1 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 KIK56065.1 - 0.025 14.9 1.3 0.43 10.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain LON_substr_bdg PF02190.16 KIK56065.1 - 0.034 14.0 0.0 0.17 11.7 0.0 1.9 1 1 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain AAA_18 PF13238.6 KIK56065.1 - 0.072 13.6 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KIK56065.1 - 0.097 12.0 0.1 0.92 8.9 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK56065.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK56065.1 - 0.17 12.4 5.6 0.78 10.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain PIG-X PF08320.12 KIK56066.1 - 2.2e-37 129.1 0.2 2.5e-37 128.8 0.2 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 TFIIS_C PF01096.18 KIK56069.1 - 2.8e-21 75.1 5.3 2.8e-21 75.1 5.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIK56069.1 - 1e-08 34.9 0.7 1e-08 34.9 0.7 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KIK56069.1 - 5e-05 23.2 7.0 0.029 14.3 1.2 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KIK56069.1 - 6.5e-05 22.8 9.2 0.0014 18.5 0.7 3.3 3 0 0 3 3 3 1 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.8 KIK56069.1 - 0.14 11.9 1.7 0.44 10.3 1.7 1.9 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Zn_ribbon_recom PF13408.6 KIK56069.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.12 KIK56069.1 - 0.32 10.5 3.9 0.58 9.7 1.0 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding PHD PF00628.29 KIK56069.1 - 0.64 10.0 13.1 0.67 9.9 2.3 2.8 2 2 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 KIK56069.1 - 0.66 10.0 9.9 0.85 9.6 0.3 2.7 2 1 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KIK56069.1 - 1.2 9.3 10.2 8.2 6.6 0.5 4.0 4 1 1 5 5 5 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KIK56069.1 - 2.6 8.0 10.1 3.6 7.6 0.4 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 KIK56069.1 - 2.8 7.8 10.8 0.95 9.2 1.9 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_15 PF17032.5 KIK56069.1 - 3.4 8.5 11.5 4.2e+02 1.8 11.6 2.7 1 1 1 2 2 2 0 zinc-ribbon family PADR1 PF08063.12 KIK56069.1 - 5.2 6.9 11.6 25 4.8 0.5 3.1 2 2 0 2 2 2 0 PADR1 (NUC008) domain Copper-fist PF00649.18 KIK56069.1 - 5.3 6.6 9.6 5.4 6.6 0.4 3.3 3 0 0 3 3 3 0 Copper fist DNA binding domain Glyco_hydro_43 PF04616.14 KIK56070.1 - 1.6e-65 221.3 0.7 2.6e-65 220.6 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIK56070.1 - 9.7e-27 94.0 0.0 1.5e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF4082 PF13313.6 KIK56073.1 - 0.052 13.6 1.3 0.097 12.7 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4082) NACHT PF05729.12 KIK56074.1 - 0.018 15.0 0.3 0.25 11.3 0.0 2.5 2 1 0 3 3 3 0 NACHT domain Arf PF00025.21 KIK56074.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KIK56074.1 - 0.056 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK56074.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK56074.1 - 0.1 13.0 0.0 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MukE PF04288.13 KIK56075.1 - 0.0016 17.5 1.1 0.0018 17.2 1.1 1.1 1 0 0 1 1 1 1 MukE-like family DFF-C PF09033.10 KIK56075.1 - 0.031 14.2 2.9 0.036 13.9 2.9 1.1 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain PriX PF18689.1 KIK56075.1 - 0.032 14.6 0.2 0.035 14.5 0.2 1.1 1 0 0 1 1 1 0 Primase X SPICE PF15678.5 KIK56078.1 - 0.014 14.8 2.1 0.017 14.5 2.1 1.1 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression PPR_2 PF13041.6 KIK56080.1 - 1.5e-11 44.3 0.3 0.00069 19.8 0.0 5.7 4 1 3 7 7 7 4 PPR repeat family PPR PF01535.20 KIK56080.1 - 6.8e-07 29.1 3.6 1.5 9.3 0.0 6.7 6 1 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 KIK56080.1 - 3.2e-05 23.9 0.0 1.3 9.2 0.0 5.0 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIK56080.1 - 0.0018 17.9 0.1 1.7 8.4 0.0 3.9 5 0 0 5 5 5 2 PPR repeat SPO22 PF08631.10 KIK56080.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Retrotran_gag_2 PF14223.6 KIK56082.1 - 1.2e-11 44.5 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK56082.1 - 0.0016 18.0 1.3 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KIK56082.1 - 0.038 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Zn_peptidase PF04228.13 KIK56082.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF2812 PF11193.8 KIK56084.1 - 0.068 13.4 0.0 0.41 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) zf-primase PF09329.11 KIK56086.1 - 0.051 13.4 1.5 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Primase zinc finger DUF2256 PF10013.9 KIK56086.1 - 0.32 11.2 0.2 0.32 11.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.12 KIK56086.1 - 0.45 10.8 12.8 0.1 12.9 8.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KIK56089.1 - 0.00091 19.9 6.3 0.019 15.8 2.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK56089.1 - 0.016 15.7 0.8 0.016 15.7 0.8 3.8 3 1 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIK56089.1 - 0.017 15.7 2.3 7 7.4 1.9 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf_ZIC PF18366.1 KIK56089.1 - 0.024 14.8 0.5 0.059 13.5 0.5 1.7 1 0 0 1 1 1 0 Zic proteins zinc finger domain zf-BED PF02892.15 KIK56089.1 - 2.6 8.1 10.1 11 6.2 0.1 3.4 3 0 0 3 3 3 0 BED zinc finger HscB_4_cys PF18256.1 KIK56090.1 - 0.078 12.8 2.3 0.23 11.3 0.2 2.8 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif zf-C2H2_4 PF13894.6 KIK56090.1 - 2 9.5 5.7 65 4.8 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger BING4CT PF08149.11 KIK56092.1 - 0.0097 15.7 0.6 6.5 6.6 0.1 3.2 1 1 3 4 4 4 3 BING4CT (NUC141) domain Cys_rich_KTR PF14205.6 KIK56094.1 - 0.037 13.8 0.3 0.045 13.5 0.3 1.2 1 0 0 1 1 1 0 Cysteine-rich KTR CxC4 PF18717.1 KIK56095.1 - 4.1e-36 123.7 0.4 1.4e-35 122.0 0.2 1.8 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases Zn-ribbon_8 PF09723.10 KIK56095.1 - 0.014 15.5 1.5 2.9 8.1 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.6 KIK56095.1 - 0.051 12.9 1.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-FPG_IleRS PF06827.14 KIK56095.1 - 0.44 10.5 9.7 0.46 10.4 0.4 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.6 KIK56095.1 - 0.76 10.2 3.0 10 6.6 0.4 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 KIK56095.1 - 4.6 6.8 6.3 0.84 9.1 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain SYCE1 PF15233.6 KIK56098.1 - 0.0046 17.0 3.2 0.0074 16.4 3.2 1.5 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF3412 PF11892.8 KIK56098.1 - 0.07 13.2 0.2 0.091 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) zf-MYND PF01753.18 KIK56100.1 - 0.011 15.8 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 0 MYND finger Transpos_assoc PF13963.6 KIK56109.1 - 0.015 15.6 0.6 0.038 14.3 0.6 1.7 1 0 0 1 1 1 0 Transposase-associated domain zf-primase PF09329.11 KIK56109.1 - 0.03 14.1 1.5 0.044 13.6 0.2 2.0 1 1 1 2 2 2 0 Primase zinc finger Zn_ribbon_recom PF13408.6 KIK56109.1 - 0.07 13.6 4.3 0.93 10.1 1.0 2.8 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf_C2H2_13 PF18508.1 KIK56109.1 - 0.081 12.5 3.1 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Zinc finger domain Nop10p PF04135.12 KIK56109.1 - 0.087 12.9 0.7 0.38 10.8 0.1 2.3 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family zf-Di19 PF05605.12 KIK56109.1 - 0.099 13.0 10.8 0.38 11.1 0.2 3.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KIK56109.1 - 2.5 9.2 8.2 2 9.5 0.1 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger Peptidase_M20 PF01546.28 KIK56110.1 - 2.6e-26 92.6 0.0 4.4e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KIK56110.1 - 1.7e-13 50.8 10.7 5.5e-05 23.9 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.14 KIK56110.1 - 1.2e-09 38.0 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 KIK56110.1 - 0.0063 15.2 1.0 0.25 9.9 0.1 2.9 2 2 1 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK56110.1 - 0.011 16.0 0.3 3.9 7.8 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RasGEF_N_2 PF14663.6 KIK56110.1 - 0.021 15.2 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GIT_SHD PF08518.11 KIK56111.1 - 3e-26 90.7 3.8 3.1e-13 49.1 0.4 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Pkinase_Tyr PF07714.17 KIK56111.1 - 6.4e-06 25.6 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Gp58 PF07902.11 KIK56111.1 - 0.016 13.5 0.1 0.023 13.0 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein Pkinase_Tyr PF07714.17 KIK56113.1 - 2.6e-26 92.5 0.0 3e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56113.1 - 1.3e-23 83.8 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK56113.1 - 0.0025 16.7 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK56113.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK56113.1 - 0.049 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK56114.1 - 2.7e-05 23.6 0.0 3.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56114.1 - 0.022 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KIK56116.1 - 9.9e-05 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KIK56117.1 - 1.6e-14 53.8 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56117.1 - 2e-11 43.7 0.0 2.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain VHL_C PF17211.3 KIK56117.1 - 0.03 14.3 0.7 0.068 13.2 0.7 1.5 1 0 0 1 1 1 0 VHL box domain MAS20 PF02064.15 KIK56118.1 - 2 8.5 7.9 6 7.0 7.9 1.8 1 0 0 1 1 1 0 MAS20 protein import receptor F-box-like PF12937.7 KIK56119.1 - 5.7e-07 29.3 0.7 2e-06 27.6 0.7 2.0 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK56119.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KIK56120.1 - 1.6e-06 27.9 3.6 1.3e-05 25.0 0.6 2.7 2 0 0 2 2 2 2 F-box-like Bac_rhamnosid_N PF08531.10 KIK56121.1 - 2.2e-05 24.4 0.5 0.0008 19.3 0.0 2.7 1 1 2 3 3 3 1 Alpha-L-rhamnosidase N-terminal domain PA14 PF07691.12 KIK56121.1 - 0.003 17.4 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 PA14 domain BetaGal_dom4_5 PF13364.6 KIK56121.1 - 0.041 14.4 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Bac_rhamnosid_N PF08531.10 KIK56122.1 - 2.9e-05 24.0 0.4 0.0098 15.7 0.0 3.9 3 2 2 5 5 5 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 KIK56122.1 - 0.00022 21.2 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain PA14 PF07691.12 KIK56122.1 - 0.014 15.2 0.0 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 PA14 domain BetaGal_dom4_5 PF13364.6 KIK56122.1 - 0.096 13.3 4.4 2 9.0 0.3 3.4 2 2 1 3 3 3 0 Beta-galactosidase jelly roll domain adh_short_C2 PF13561.6 KIK56124.1 - 1e-53 182.3 0.1 1.3e-53 182.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK56124.1 - 4.8e-37 127.3 0.1 5.9e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK56124.1 - 4e-14 52.9 0.1 5.9e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Pkinase_Tyr PF07714.17 KIK56125.1 - 9.8e-15 54.5 0.0 1.3e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56125.1 - 1e-10 41.4 0.0 1.3e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK56126.1 - 1.7e-21 76.7 0.0 1.9e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56126.1 - 8.8e-16 58.1 0.0 1e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 KIK56127.1 - 1.8e-17 62.7 1.9 1.3e-08 34.3 0.1 2.8 2 1 0 2 2 2 2 SH3 domain HSF_DNA-bind PF00447.17 KIK56127.1 - 3.3e-13 50.1 0.0 5.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding SH3_9 PF14604.6 KIK56127.1 - 4.1e-11 42.5 0.5 0.00026 20.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KIK56127.1 - 2.5e-07 30.3 1.0 2.7e-05 23.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 KIK56127.1 - 4.1e-05 24.1 0.0 9.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KIK56127.1 - 0.016 15.5 3.3 3.1 8.2 0.3 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_1 PF00018.28 KIK56128.1 - 4.1e-10 39.1 0.0 6.6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK56128.1 - 9.2e-07 28.6 0.1 1.5e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK56130.1 - 2.2e-08 33.6 0.5 3.6e-08 32.9 0.5 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK56130.1 - 2e-05 24.2 0.2 3e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK56130.1 - 0.0001 22.1 0.2 0.00015 21.5 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KIK56130.1 - 0.062 13.6 1.3 0.1 12.9 1.3 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase_Tyr PF07714.17 KIK56131.1 - 2.2e-41 141.9 0.0 3.3e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56131.1 - 3.5e-33 115.1 0.0 3.8e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain SH3_1 PF00018.28 KIK56131.1 - 3.6e-16 58.5 1.1 8.4e-08 31.7 0.1 2.7 2 1 0 2 2 2 2 SH3 domain HSF_DNA-bind PF00447.17 KIK56131.1 - 1.9e-10 41.2 0.0 3.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding SH3_9 PF14604.6 KIK56131.1 - 8.3e-10 38.4 0.7 5.9e-05 22.9 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KIK56131.1 - 1.8e-07 30.8 0.6 6.1e-06 25.8 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain RA PF00788.23 KIK56131.1 - 0.00065 20.3 0.0 0.0022 18.6 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain APH PF01636.23 KIK56131.1 - 0.01 15.8 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK56131.1 - 0.043 12.6 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF5632 PF18646.1 KIK56131.1 - 0.05 13.7 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5632) SH3_3 PF08239.11 KIK56131.1 - 0.056 13.7 2.1 0.1 12.9 1.1 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain Pkinase_Tyr PF07714.17 KIK56132.1 - 2.9e-19 69.4 0.0 3.9e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56132.1 - 2.6e-15 56.5 0.0 3.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK56132.1 - 0.0034 16.2 0.0 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK56132.1 - 0.036 14.0 0.1 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.17 KIK56133.1 - 1.3e-16 60.9 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Bac_rhamnosid_N PF08531.10 KIK56134.1 - 7.9e-06 25.8 2.2 0.0021 17.9 0.2 3.7 3 1 0 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain BetaGal_dom4_5 PF13364.6 KIK56134.1 - 0.00038 21.0 1.3 0.98 10.0 0.1 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Ald_Xan_dh_C2 PF02738.18 KIK56134.1 - 0.075 11.5 0.3 0.11 11.0 0.3 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Pkinase_Tyr PF07714.17 KIK56135.1 - 2e-42 145.3 0.0 2.7e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56135.1 - 3.3e-34 118.5 0.0 4.6e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK56135.1 - 6.5e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK56135.1 - 0.00067 19.7 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK56136.1 - 4.8e-13 49.0 0.0 6.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56136.1 - 3.9e-11 42.8 0.0 5.7e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain T3SS_needle_F PF09392.10 KIK56136.1 - 0.077 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HSP70 PF00012.20 KIK56137.1 - 0.00034 18.9 0.0 0.00067 18.0 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 KIK56137.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family RNase_P_Rpp14 PF01900.19 KIK56138.1 - 7.4e-07 29.4 0.0 1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family ABC_tran_Xtn PF12848.7 KIK56138.1 - 0.36 10.9 2.9 0.48 10.5 0.4 2.0 1 1 1 2 2 2 0 ABC transporter Pkinase_Tyr PF07714.17 KIK56139.1 - 2.6e-39 135.1 0.0 3e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56139.1 - 1.3e-31 109.9 0.0 1.6e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK56139.1 - 0.001 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK56139.1 - 0.0014 18.6 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RNase_P_Rpp14 PF01900.19 KIK56141.1 - 3e-27 94.9 0.0 3.8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ABC_tran_Xtn PF12848.7 KIK56141.1 - 0.26 11.3 3.3 1.6 8.8 0.5 2.2 1 1 1 2 2 2 0 ABC transporter AA_permease_2 PF13520.6 KIK56143.1 - 9.7e-60 202.6 43.9 1.2e-59 202.3 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK56143.1 - 5.6e-17 61.5 36.8 9.4e-17 60.8 36.8 1.4 1 1 0 1 1 1 1 Amino acid permease Phage_holin_5_1 PF06946.11 KIK56143.1 - 0.016 15.6 1.1 0.063 13.7 0.5 2.4 1 1 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 GWT1 PF06423.12 KIK56143.1 - 2.7 8.1 6.7 7.2 6.7 0.5 3.8 4 1 0 4 4 4 0 GWT1 TMEM82 PF15816.5 KIK56144.1 - 0.051 12.5 0.1 0.052 12.5 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 82 Bac_rhamnosid_N PF08531.10 KIK56146.1 - 0.00079 19.3 0.5 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_N PF08531.10 KIK56147.1 - 2e-05 24.5 2.7 0.0086 15.9 0.1 3.9 3 1 0 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain BetaGal_dom4_5 PF13364.6 KIK56147.1 - 0.0023 18.5 0.9 3.1 8.4 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain DUF3450 PF11932.8 KIK56149.1 - 1.5e-07 31.0 29.2 2.1e-05 23.9 12.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) BRE1 PF08647.11 KIK56149.1 - 0.00014 21.8 24.5 0.13 12.3 15.3 2.5 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.20 KIK56149.1 - 0.00016 21.2 34.0 0.00021 20.8 34.0 1.1 1 0 0 1 1 1 1 Tropomyosin ATG16 PF08614.11 KIK56149.1 - 0.00044 20.6 33.6 0.0037 17.5 18.5 2.7 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KIK56149.1 - 0.0027 17.6 24.7 0.0027 17.6 24.7 2.2 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KIK56149.1 - 0.003 17.6 16.2 0.026 14.6 3.6 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 KIK56149.1 - 0.0045 17.0 29.4 0.093 12.7 9.9 3.4 1 1 3 4 4 4 3 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 KIK56149.1 - 0.0049 17.4 26.9 0.33 11.6 6.2 3.1 1 1 2 3 3 3 3 Bone marrow stromal antigen 2 Spc7 PF08317.11 KIK56149.1 - 0.0066 15.4 29.7 0.012 14.5 29.7 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein GOLGA2L5 PF15070.6 KIK56149.1 - 0.0079 14.9 29.6 0.0093 14.7 29.6 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF1465 PF07323.12 KIK56149.1 - 0.0088 15.9 14.9 0.21 11.4 1.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1465) Cluap1 PF10234.9 KIK56149.1 - 0.01 15.2 25.0 0.018 14.5 13.0 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 ADIP PF11559.8 KIK56149.1 - 0.014 15.5 30.1 0.3 11.1 16.8 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.10 KIK56149.1 - 0.019 15.3 26.7 0.08 13.3 4.0 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Peptidase_M75 PF09375.10 KIK56149.1 - 0.022 14.3 6.2 0.033 13.7 6.0 1.4 1 1 0 1 1 1 0 Imelysin Jnk-SapK_ap_N PF09744.9 KIK56149.1 - 0.029 14.6 34.6 1.2 9.3 23.4 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ERM PF00769.19 KIK56149.1 - 0.029 14.2 41.5 0.027 14.3 31.6 2.0 1 1 0 2 2 2 0 Ezrin/radixin/moesin family TACC_C PF05010.14 KIK56149.1 - 0.029 14.1 24.6 0.036 13.8 24.6 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CALCOCO1 PF07888.11 KIK56149.1 - 0.04 12.8 30.6 0.049 12.5 30.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.10 KIK56149.1 - 0.058 13.6 20.3 0.32 11.2 13.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 KIK56149.1 - 0.063 13.3 35.2 0.024 14.6 15.4 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 KIK56149.1 - 0.07 12.7 32.2 0.21 11.1 19.3 2.5 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Atg14 PF10186.9 KIK56149.1 - 0.1 11.7 26.1 0.18 10.8 19.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KIK56149.1 - 0.16 12.5 39.7 1.8 9.1 21.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region IFT57 PF10498.9 KIK56149.1 - 0.19 10.6 26.8 0.027 13.4 15.4 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 bZIP_1 PF00170.21 KIK56149.1 - 0.23 11.6 25.4 0.19 11.8 2.4 4.0 2 1 1 4 4 3 0 bZIP transcription factor Sec34 PF04136.15 KIK56149.1 - 0.24 11.3 15.8 0.88 9.4 4.3 2.6 1 1 2 3 3 3 0 Sec34-like family GAS PF13851.6 KIK56149.1 - 0.26 10.6 30.6 1.8 7.9 17.2 2.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding EntA_Immun PF08951.10 KIK56149.1 - 0.27 11.6 6.0 0.57 10.6 0.1 2.9 3 0 0 3 3 3 0 Enterocin A Immunity DUF724 PF05266.14 KIK56149.1 - 0.31 10.8 25.5 1.3 8.8 12.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) NRBF2 PF08961.10 KIK56149.1 - 0.31 10.6 14.3 0.49 10.0 14.3 1.4 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Med9 PF07544.13 KIK56149.1 - 0.31 11.1 22.8 0.74 9.9 5.6 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HOOK PF05622.12 KIK56149.1 - 0.32 9.1 31.6 1.6 6.7 20.4 2.1 1 1 1 2 2 2 0 HOOK protein COG5 PF10392.9 KIK56149.1 - 0.38 10.9 14.4 1.1 9.4 9.3 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Tropomyosin_1 PF12718.7 KIK56149.1 - 0.48 10.6 35.7 1.1 9.4 25.7 2.3 1 1 1 2 2 2 0 Tropomyosin like Vps5 PF09325.10 KIK56149.1 - 0.49 9.9 21.2 1.3 8.5 3.6 3.0 1 1 2 3 3 3 0 Vps5 C terminal like GrpE PF01025.19 KIK56149.1 - 0.51 10.0 29.2 0.44 10.2 5.5 3.1 1 1 2 3 3 3 0 GrpE DUF948 PF06103.11 KIK56149.1 - 0.51 10.6 9.2 5.8 7.2 2.1 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 KIK56149.1 - 0.58 10.6 24.1 0.096 13.1 2.1 4.2 1 1 3 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CC2-LZ PF16516.5 KIK56149.1 - 0.59 10.5 25.7 4.5 7.7 1.4 3.5 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.6 KIK56149.1 - 0.6 9.4 21.8 1.8 7.9 21.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KIK56149.1 - 0.69 10.2 34.3 1.1 9.5 16.3 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4686 PF15742.5 KIK56149.1 - 0.72 8.9 33.8 0.21 10.7 18.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Baculo_PEP_C PF04513.12 KIK56149.1 - 0.88 9.6 12.1 4.8e+02 0.7 12.1 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KIK56149.1 - 0.94 7.3 13.2 2.2 6.1 13.2 1.6 1 1 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.22 KIK56149.1 - 1.1 9.6 22.1 1 9.6 8.8 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ISG65-75 PF11727.8 KIK56149.1 - 1.1 8.4 14.6 0.15 11.3 8.6 1.9 1 1 1 2 2 2 0 Invariant surface glycoprotein Fez1 PF06818.15 KIK56149.1 - 1.1 9.6 29.2 9.7 6.6 19.0 2.0 1 1 1 2 2 2 0 Fez1 DUF4250 PF14056.6 KIK56149.1 - 1.2 9.2 5.2 0.65 10.0 0.2 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4250) OmpH PF03938.14 KIK56149.1 - 1.3 9.3 30.4 0.9 9.9 17.6 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 KIK56149.1 - 1.3 9.0 32.2 0.11 12.5 2.9 4.1 1 1 3 4 4 3 0 Prefoldin subunit DUF3584 PF12128.8 KIK56149.1 - 1.3 6.4 30.2 3.9 4.9 30.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Phlebovirus_NSM PF07246.11 KIK56149.1 - 1.4 8.3 13.7 2.5 7.4 5.1 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M YscO PF07321.12 KIK56149.1 - 1.6 8.6 35.6 9.2 6.2 11.0 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO MAD PF05557.13 KIK56149.1 - 1.8 6.9 32.2 2.6 6.3 32.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.15 KIK56149.1 - 1.8 8.4 28.9 0.21 11.4 3.7 3.9 1 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KIK56149.1 - 2.5 8.2 36.0 12 6.0 7.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FPP PF05911.11 KIK56149.1 - 2.6 6.1 31.3 0.11 10.7 17.3 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 KIK56149.1 - 2.6 6.6 22.6 0.27 9.8 5.2 2.0 1 1 1 2 2 2 0 AAA domain Rho_Binding PF08912.11 KIK56149.1 - 3 8.7 30.2 4.6 8.1 5.7 3.8 2 1 1 3 3 3 0 Rho Binding I_LWEQ PF01608.17 KIK56149.1 - 3.1 8.0 21.8 0.57 10.4 14.6 2.2 1 1 1 2 2 2 0 I/LWEQ domain TMPIT PF07851.13 KIK56149.1 - 3.5 6.8 19.8 24 4.1 19.4 2.2 1 1 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.6 KIK56149.1 - 3.6 8.0 33.0 1.6 9.2 0.8 3.3 1 1 3 4 4 3 0 Domain of unknown function (DUF4200) Mod_r PF07200.13 KIK56149.1 - 3.7 7.6 27.7 26 4.9 27.5 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ABC_tran_CTD PF16326.5 KIK56149.1 - 4.1 7.7 38.9 0.63 10.3 2.2 4.9 1 1 4 5 5 5 0 ABC transporter C-terminal domain ApoO PF09769.9 KIK56149.1 - 4.4 7.3 5.8 3.2 7.7 1.4 2.5 1 1 2 3 3 3 0 Apolipoprotein O HAUS-augmin3 PF14932.6 KIK56149.1 - 4.8 6.7 29.8 1.8 8.0 10.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF812 PF05667.11 KIK56149.1 - 5.1 5.9 31.2 0.6 8.9 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.9 KIK56149.1 - 5.1 7.0 29.2 0.65 9.9 11.0 2.7 1 1 2 3 3 3 0 Axonemal dynein light chain SlyX PF04102.12 KIK56149.1 - 5.5 7.7 32.3 5.1 7.8 7.0 4.0 1 1 2 3 3 3 0 SlyX Exonuc_VII_L PF02601.15 KIK56149.1 - 5.6 6.4 22.6 10 5.6 22.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit ZapB PF06005.12 KIK56149.1 - 5.7 7.5 40.7 0.58 10.6 3.4 3.7 1 1 2 3 3 3 0 Cell division protein ZapB UPF0242 PF06785.11 KIK56149.1 - 5.8 7.0 33.3 0.83 9.7 22.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 KIK56149.1 - 5.9 6.1 26.2 5.7 6.1 10.3 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DASH_Spc19 PF08287.11 KIK56149.1 - 5.9 6.8 25.6 0.89 9.4 13.7 2.2 1 1 1 2 2 2 0 Spc19 HMMR_N PF15905.5 KIK56149.1 - 6 6.2 31.4 8.2 5.8 20.3 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PI3K_P85_iSH2 PF16454.5 KIK56149.1 - 6.1 6.4 27.2 0.81 9.3 13.3 2.8 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DHR10 PF18595.1 KIK56149.1 - 6.5 6.9 38.0 7.4 6.7 7.6 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4618 PF15397.6 KIK56149.1 - 6.8 6.0 26.3 1.2e+03 -1.3 26.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 KIK56149.1 - 8 5.8 36.0 7.5 5.9 24.4 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF16 PF01519.16 KIK56149.1 - 8 7.0 21.1 45 4.6 7.3 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Perilipin PF03036.16 KIK56149.1 - 8 5.4 17.8 16 4.3 17.7 1.6 1 1 0 1 1 1 0 Perilipin family SHE3 PF17078.5 KIK56149.1 - 8.2 6.1 24.4 1.9e+02 1.6 14.8 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 KIK56149.1 - 8.3 4.9 21.2 22 3.5 13.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 KIK56149.1 - 8.4 7.1 31.7 1.2e+02 3.4 23.1 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ALMT PF11744.8 KIK56149.1 - 9.6 4.9 16.3 11 4.7 16.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-C4pol PF14260.6 KIK56149.1 - 9.6 6.8 7.2 7.8 7.0 0.2 3.4 1 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Atg14 PF10186.9 KIK56150.1 - 0.00051 19.2 3.5 0.00071 18.8 3.5 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CHD5 PF04420.14 KIK56150.1 - 0.13 12.2 5.8 0.046 13.6 3.4 1.6 2 0 0 2 2 2 0 CHD5-like protein ADIP PF11559.8 KIK56150.1 - 0.54 10.3 14.5 0.92 9.6 14.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HOOK PF05622.12 KIK56150.1 - 0.8 7.8 14.4 1 7.4 14.4 1.1 1 0 0 1 1 1 0 HOOK protein MT PF12777.7 KIK56150.1 - 1.5 7.7 6.7 2.1 7.3 6.7 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor SseC PF04888.12 KIK56150.1 - 2.3 7.7 6.9 3.2 7.2 6.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Mod_r PF07200.13 KIK56150.1 - 4.4 7.4 14.7 7 6.7 14.7 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF724 PF05266.14 KIK56150.1 - 5.2 6.8 10.1 8.5 6.1 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF16 PF01519.16 KIK56150.1 - 5.9 7.4 10.9 12 6.5 10.9 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 MT-A70 PF05063.14 KIK56151.1 - 4.2e-39 134.2 0.0 8.2e-39 133.3 0.0 1.5 1 1 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 KIK56151.1 - 0.23 11.3 0.1 0.38 10.6 0.1 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Noc2 PF03715.13 KIK56152.1 - 1.5e-116 388.9 5.2 7e-116 386.7 3.3 2.2 2 0 0 2 2 2 1 Noc2p family Astro_capsid_p PF12226.8 KIK56152.1 - 1.1 8.3 10.6 2.6 7.1 10.6 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HSP70 PF00012.20 KIK56154.1 - 0.051 11.8 0.0 0.14 10.3 0.0 1.6 1 1 0 1 1 1 0 Hsp70 protein BcrAD_BadFG PF01869.20 KIK56154.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family ALO PF04030.14 KIK56155.1 - 1.4e-74 251.2 1.7 2e-74 250.7 1.7 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK56155.1 - 3.9e-27 94.7 0.1 6e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.26 KIK56156.1 - 2.6e-45 153.5 0.0 3e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK56156.1 - 0.11 12.1 0.0 0.39 10.4 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B RNA_pol_Rpb2_6 PF00562.28 KIK56157.1 - 4e-126 421.2 0.2 5.4e-126 420.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIK56157.1 - 6.6e-57 192.3 0.0 1.6e-56 191.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KIK56157.1 - 2.9e-32 110.9 0.2 7e-32 109.7 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIK56157.1 - 4.9e-26 91.5 0.0 1.7e-25 89.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KIK56157.1 - 2.5e-25 88.6 2.6 4.7e-25 87.7 1.4 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIK56157.1 - 2.7e-20 72.3 0.0 5.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIK56157.1 - 4.5e-10 39.9 0.1 1.4e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.26 KIK56158.1 - 1.6e-46 157.5 0.0 1.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK56158.1 - 0.0034 17.1 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B SNF2_N PF00176.23 KIK56159.1 - 9.6e-40 136.4 0.0 1.7e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK56159.1 - 5.5e-19 68.6 0.0 1.6e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 KIK56159.1 - 2.2e-05 24.5 0.3 2.2e-05 24.5 0.3 2.5 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal ERCC3_RAD25_C PF16203.5 KIK56159.1 - 8e-05 22.0 0.0 0.0002 20.7 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIK56159.1 - 0.0005 20.1 2.4 0.0072 16.3 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Rol_Rep_N PF18106.1 KIK56159.1 - 0.0022 18.2 1.0 0.33 11.3 0.1 3.9 5 0 0 5 5 5 1 Rolling Circle replication initiation protein N-terminal domain SEC-C PF02810.15 KIK56159.1 - 0.034 14.1 6.3 0.062 13.2 6.3 1.5 1 0 0 1 1 1 0 SEC-C motif bZIP_2 PF07716.15 KIK56160.1 - 2.5e-06 27.5 4.7 4.5e-06 26.6 4.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK56160.1 - 0.00062 19.8 4.1 0.0012 18.9 4.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIK56160.1 - 0.0012 19.3 1.5 0.0012 19.3 1.5 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor Cellulase PF00150.18 KIK56161.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TEA PF01285.18 KIK56163.1 - 3.8e-21 74.9 0.0 6.3e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain MFS_1 PF07690.16 KIK56164.1 - 1.2e-46 159.3 57.9 2e-46 158.5 57.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK56164.1 - 5e-16 58.3 24.9 6.9e-16 57.8 24.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK56164.1 - 2e-14 53.3 13.5 2e-14 53.3 13.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DZF PF07528.14 KIK56164.1 - 0.017 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 DZF domain aGPT-Pplase1 PF18723.1 KIK56165.1 - 6.1e-104 347.4 0.0 7.8e-104 347.0 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 KIK56165.1 - 6e-08 32.5 0.3 1.4e-07 31.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Copper-fist PF00649.18 KIK56166.1 - 4.3e-15 54.9 2.0 4.3e-15 54.9 2.0 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain Got1 PF04178.12 KIK56167.1 - 8.3e-30 103.5 14.7 1.1e-29 103.1 14.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KIK56167.1 - 0.68 8.2 4.8 0.76 8.0 4.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YfhO PF09586.10 KIK56167.1 - 0.92 7.7 8.4 1.3 7.2 8.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2157 PF09925.9 KIK56167.1 - 0.98 9.2 9.5 3.3 7.5 9.5 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2304 PF10066.9 KIK56167.1 - 6.2 7.1 8.4 8.9 6.6 7.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Nup192 PF11894.8 KIK56168.1 - 2.1e-249 830.8 0.0 2.5e-249 830.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 CE2_N PF17996.1 KIK56169.1 - 0.00091 19.2 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal adh_short PF00106.25 KIK56170.1 - 2.8e-29 102.0 0.0 1.3e-27 96.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56170.1 - 4.7e-13 49.2 0.0 1.3e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK56170.1 - 5.9e-06 26.3 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK56170.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK56170.1 - 0.0055 16.2 0.0 0.0067 15.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK56173.1 - 8.5e-27 93.9 0.0 2.1e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56173.1 - 3e-13 49.9 0.0 9.9e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK56173.1 - 7.4e-06 26.0 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK56173.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 KIK56173.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KIK56174.1 - 7.3e-16 58.2 0.0 2.4e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56174.1 - 4.7e-07 29.6 0.0 3.1e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L37 PF08561.10 KIK56175.1 - 7.7e-16 58.7 11.3 1.1e-14 55.0 0.5 2.5 2 1 1 3 3 3 2 Mitochondrial ribosomal protein L37 Dehydrin PF00257.19 KIK56175.1 - 0.33 11.5 2.0 0.63 10.6 2.0 1.4 1 0 0 1 1 1 0 Dehydrin AA_permease_2 PF13520.6 KIK56176.1 - 8.6e-59 199.4 56.7 1e-58 199.2 56.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK56176.1 - 8.1e-11 41.2 55.0 1.3e-10 40.4 55.0 1.3 1 1 0 1 1 1 1 Amino acid permease PalH PF08733.10 KIK56176.1 - 4.9 6.1 13.2 0.11 11.4 6.0 1.9 2 0 0 2 2 2 0 PalH/RIM21 Peptidase_C65 PF10275.9 KIK56177.1 - 8.4e-66 221.9 0.0 1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KIK56177.1 - 5.6e-08 33.3 0.0 9.6e-05 22.9 0.0 2.6 2 1 0 2 2 2 2 OTU-like cysteine protease zf-C2H2 PF00096.26 KIK56178.1 - 0.049 14.1 4.2 0.049 14.1 4.2 1.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Meth_synt_2 PF01717.18 KIK56179.1 - 0.00014 21.3 0.1 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain RST PF12174.8 KIK56179.1 - 0.0048 16.8 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain Meth_synt_2 PF01717.18 KIK56180.1 - 0.011 15.0 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain Meth_synt_2 PF01717.18 KIK56181.1 - 0.0013 18.1 0.0 0.74 9.0 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain RST PF12174.8 KIK56181.1 - 0.0094 15.9 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain Meth_synt_2 PF01717.18 KIK56182.1 - 0.0012 18.2 0.1 0.97 8.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Goodbye PF17109.5 KIK56184.1 - 7.1e-05 23.2 0.0 8.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KIK56185.1 - 0.0033 17.4 0.0 0.0075 16.2 0.0 1.6 1 1 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KIK56186.1 - 1.8e-29 102.1 10.1 3.3e-12 46.8 0.7 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KIK56186.1 - 1e-22 79.5 13.6 1.2e-06 28.7 0.7 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KIK56186.1 - 3.4e-21 75.0 3.8 2.9e-09 37.0 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK56186.1 - 1.3e-20 71.3 6.2 1.1e-06 28.5 0.3 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KIK56186.1 - 1.7e-20 73.1 5.9 2e-08 34.6 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) KAsynt_C_assoc PF16197.5 KIK56186.1 - 0.081 13.4 0.1 0.17 12.4 0.1 1.6 1 1 1 2 2 2 0 Ketoacyl-synthetase C-terminal extension Mic1 PF07035.12 KIK56186.1 - 0.15 11.8 0.2 0.84 9.3 0.2 2.0 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like Pkinase_Tyr PF07714.17 KIK56187.1 - 3e-50 170.9 0.0 4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56187.1 - 6.3e-49 166.7 0.0 9e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KIK56187.1 - 1.3e-07 31.4 0.8 2.9e-07 30.2 0.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 KIK56187.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK56187.1 - 0.0034 17.3 0.0 0.0056 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK56187.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PHD PF00628.29 KIK56187.1 - 0.031 14.2 4.4 0.076 12.9 4.4 1.6 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KIK56187.1 - 0.048 14.0 1.0 0.1 12.9 1.0 1.6 1 0 0 1 1 1 0 C1 domain Haspin_kinase PF12330.8 KIK56187.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Prok-RING_1 PF14446.6 KIK56187.1 - 0.11 12.4 7.4 0.052 13.5 4.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Arf PF00025.21 KIK56188.1 - 3.6e-38 130.7 0.0 1.7e-37 128.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK56188.1 - 3.5e-13 49.4 0.1 6.2e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIK56188.1 - 3.9e-10 40.0 0.0 6.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK56188.1 - 1e-08 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KIK56188.1 - 3.1e-07 30.0 0.0 5.3e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK56188.1 - 4.5e-07 29.5 0.0 5.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK56188.1 - 4.2e-06 26.8 0.0 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK56188.1 - 8e-05 22.3 0.0 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK56188.1 - 0.0013 18.7 0.1 0.93 9.4 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KIK56188.1 - 0.0019 17.8 0.1 0.41 10.2 0.2 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIK56188.1 - 0.0025 17.5 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK56188.1 - 0.0029 18.1 0.5 0.0044 17.5 0.4 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KIK56188.1 - 0.0033 18.0 1.5 0.005 17.4 1.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK56188.1 - 0.0088 16.3 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK56188.1 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KIK56188.1 - 0.021 14.0 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KIK56188.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 KIK56188.1 - 0.052 13.2 0.2 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Thymidylate kinase SRP54 PF00448.22 KIK56188.1 - 0.057 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KIK56188.1 - 0.088 13.4 0.6 0.19 12.3 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK56188.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK56188.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KIK56188.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KIK56188.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 KIK56190.1 - 1.1e-72 240.3 59.1 6.2e-14 52.0 1.8 8.7 5 3 4 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56190.1 - 9.1e-49 159.7 50.4 7.9e-05 22.5 0.2 12.9 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56190.1 - 1.4e-40 135.5 54.4 0.00018 21.2 0.2 13.0 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 KIK56190.1 - 2e-34 114.9 54.4 0.0055 16.8 0.5 13.3 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56190.1 - 2.9e-23 82.8 17.1 2.1e-10 40.5 4.7 4.3 1 1 3 4 4 4 4 MalT-like TPR region TPR_10 PF13374.6 KIK56190.1 - 4.4e-23 80.4 40.8 0.091 12.7 0.0 12.8 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_14 PF13428.6 KIK56190.1 - 1.9e-22 78.0 22.9 0.67 10.9 0.1 13.1 12 1 1 13 13 12 4 Tetratricopeptide repeat SNAP PF14938.6 KIK56190.1 - 5.2e-20 72.0 21.5 1.4e-08 34.6 3.1 4.8 2 1 3 5 5 5 5 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KIK56190.1 - 2.4e-17 63.3 30.1 0.074 13.7 0.1 10.7 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56190.1 - 3.7e-17 62.6 55.0 0.00019 21.9 4.8 11.0 2 2 11 13 13 13 10 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56190.1 - 2.9e-15 55.1 36.2 0.3 11.2 0.1 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 KIK56190.1 - 7.2e-13 48.3 41.8 0.46 11.2 0.4 13.1 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_21 PF09976.9 KIK56190.1 - 7.8e-11 42.0 32.6 0.039 13.6 1.0 7.8 2 1 6 8 8 8 5 Tetratricopeptide repeat-like domain NB-ARC PF00931.22 KIK56190.1 - 2.3e-10 40.1 0.0 6.3e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.6 KIK56190.1 - 2.1e-09 36.9 48.0 0.19 11.4 0.3 11.8 11 1 0 11 11 11 5 TPR repeat AAA_16 PF13191.6 KIK56190.1 - 8.9e-07 29.4 3.7 9.7e-06 26.1 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain Wzy_C_2 PF11846.8 KIK56190.1 - 5.6e-05 23.1 9.9 0.23 11.4 0.1 4.4 1 1 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal AAA_22 PF13401.6 KIK56190.1 - 7.7e-05 23.0 1.7 0.00087 19.6 0.0 3.3 2 1 0 3 3 3 1 AAA domain DUF2225 PF09986.9 KIK56190.1 - 0.00018 21.3 27.3 0.0088 15.8 1.1 5.5 1 1 5 6 6 6 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 KIK56190.1 - 0.00021 21.0 25.3 1.1 9.0 0.8 7.3 2 1 7 9 9 9 2 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 KIK56190.1 - 0.00029 20.2 38.2 1.2 8.7 0.1 10.2 12 0 0 12 12 11 2 SHNi-TPR TPR_9 PF13371.6 KIK56190.1 - 0.00055 20.0 22.4 3.7 7.8 0.1 9.1 3 2 7 10 10 10 1 Tetratricopeptide repeat HetR_C PF18460.1 KIK56190.1 - 0.0013 18.7 11.2 4 7.4 0.1 7.6 3 2 2 8 8 8 1 Heterocyst differentiation regulator C-terminal Hood domain ATPase_2 PF01637.18 KIK56190.1 - 0.0014 18.5 0.0 0.005 16.8 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_pol_L_2 PF13656.6 KIK56190.1 - 0.004 16.9 4.1 15 5.4 0.1 6.8 8 1 1 9 9 7 0 RNA polymerase Rpb3/Rpb11 dimerisation domain NACHT PF05729.12 KIK56190.1 - 0.0074 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 KIK56190.1 - 0.011 16.1 24.1 3.8 8.1 0.0 9.8 10 1 1 11 11 8 0 Tetratricopeptide repeat FlaC_arch PF05377.11 KIK56190.1 - 0.016 15.6 20.2 12 6.4 0.0 9.2 11 0 0 11 11 10 0 Flagella accessory protein C (FlaC) Cystatin PF00031.21 KIK56190.1 - 0.019 15.3 24.4 4.1 7.8 0.2 9.3 11 0 0 11 11 11 0 Cystatin domain DUF4122 PF13498.6 KIK56190.1 - 0.042 13.5 12.7 1.2 8.8 0.0 4.5 3 1 1 5 5 5 0 Domain of unknown function (DUF4122) TniB PF05621.11 KIK56190.1 - 0.075 12.4 0.0 0.37 10.2 0.0 2.2 1 1 0 1 1 1 0 Bacterial TniB protein RPN6_N PF18055.1 KIK56190.1 - 0.12 12.7 19.3 2.1 8.7 0.1 7.2 2 2 6 8 8 8 0 26S proteasome regulatory subunit RPN6 N-terminal domain AAA_14 PF13173.6 KIK56190.1 - 0.23 11.5 2.4 1.3 9.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain MAS20 PF02064.15 KIK56190.1 - 0.37 10.9 5.5 3e+02 1.5 0.0 6.3 10 0 0 10 10 6 0 MAS20 protein import receptor FBPase PF00316.20 KIK56190.1 - 0.39 10.2 3.6 8 5.9 0.3 3.2 1 1 1 3 3 3 0 Fructose-1-6-bisphosphatase, N-terminal domain Perilipin PF03036.16 KIK56190.1 - 0.44 9.5 6.9 3.2 6.7 0.5 3.2 1 1 3 4 4 4 0 Perilipin family DUF4810 PF16068.5 KIK56190.1 - 1.2 9.8 25.4 74 4.0 0.1 9.7 9 3 2 11 11 9 0 Domain of unknown function (DUF4810) BORCS7 PF16088.5 KIK56190.1 - 9.8 6.5 23.0 6.3 7.1 0.3 7.0 7 2 4 11 11 8 0 BLOC-1-related complex sub-unit 7 Ric8 PF10165.9 KIK56191.1 - 2.7e-110 369.6 0.0 3.3e-110 369.3 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF2770 PF10968.8 KIK56193.1 - 0.37 10.8 2.1 9.6 6.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) DUF89 PF01937.19 KIK56194.1 - 1.6e-108 362.8 0.0 1.8e-108 362.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF3552 PF12072.8 KIK56194.1 - 0.1 12.0 0.3 0.21 11.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RR_TM4-6 PF06459.12 KIK56195.1 - 5.4 6.8 6.0 8 6.2 6.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BolA PF01722.18 KIK56196.1 - 3.5e-16 59.3 0.2 7.8e-16 58.1 0.2 1.5 1 1 0 1 1 1 1 BolA-like protein Amidohydro_2 PF04909.14 KIK56197.1 - 3e-17 63.4 0.4 6.4e-17 62.3 0.1 1.6 2 0 0 2 2 2 1 Amidohydrolase TatD_DNase PF01026.21 KIK56197.1 - 0.031 13.7 0.0 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 TatD related DNase VRP1 PF03538.14 KIK56198.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein Acetyltransf_1 PF00583.25 KIK56199.1 - 6.8e-17 61.8 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIK56199.1 - 5.8e-10 39.0 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK56199.1 - 2.4e-09 37.2 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK56199.1 - 8.8e-09 35.7 0.3 1.6e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK56199.1 - 3.5e-06 26.7 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK56199.1 - 9e-06 25.8 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK56199.1 - 4.4e-05 24.2 0.0 5.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK56199.1 - 0.0006 20.0 0.0 0.00073 19.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK56199.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase F-box-like PF12937.7 KIK56200.1 - 6.3e-07 29.2 0.7 1.4e-06 28.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK56200.1 - 0.066 13.1 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 F-box domain DNA_pol_A_exo1 PF01612.20 KIK56201.1 - 4.3e-09 36.3 0.0 5.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease zf-C3HC4 PF00097.25 KIK56202.1 - 3.4e-08 33.2 3.8 7.6e-08 32.1 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK56202.1 - 2.9e-06 27.1 5.9 6e-06 26.1 5.9 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIK56202.1 - 5.4e-06 26.2 10.9 4.2e-05 23.3 10.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK56202.1 - 9.8e-06 25.5 4.8 9.8e-06 25.5 4.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK56202.1 - 1.7e-05 25.1 6.5 3e-05 24.3 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK56202.1 - 0.00082 19.2 9.7 0.00089 19.1 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK56202.1 - 0.0079 16.0 13.2 0.38 10.6 13.5 2.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK56202.1 - 2.3 8.5 10.7 1.2 9.4 5.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING A_deaminase PF00962.22 KIK56203.1 - 6.8e-21 74.9 0.0 2.6e-20 73.0 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KIK56204.1 - 6.5e-70 236.1 0.1 8.8e-70 235.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK56204.1 - 5.5e-10 39.3 0.0 6e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KIK56204.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3863 PF12979.7 KIK56204.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) NIF PF03031.18 KIK56206.1 - 2.7e-40 137.7 0.3 8.1e-40 136.1 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Sperm_Ag_HE2 PF05324.13 KIK56206.1 - 0.074 13.5 1.1 0.23 11.9 1.1 1.9 1 0 0 1 1 1 0 Sperm antigen HE2 adh_short PF00106.25 KIK56207.1 - 8.6e-24 84.1 0.0 7.4e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56207.1 - 3.5e-13 49.7 0.0 5.9e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK56207.1 - 8.8e-08 32.3 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK56207.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KIK56207.1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPR_12 PF13424.6 KIK56209.1 - 7.2e-05 23.0 3.3 0.22 11.8 0.2 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK56209.1 - 0.0032 16.9 0.0 0.0091 15.4 0.0 1.8 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 KIK56209.1 - 0.014 15.4 0.2 12 6.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK56209.1 - 0.081 12.6 0.6 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 NB-ARC PF00931.22 KIK56211.1 - 2.3e-05 23.7 0.0 3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK56211.1 - 6.1e-05 23.5 0.0 7.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK56211.1 - 0.015 14.2 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 KIK56211.1 - 0.069 13.2 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 KIK56211.1 - 0.081 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 KIK56211.1 - 0.087 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KIK56211.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 KIK56211.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_35 PF14516.6 KIK56211.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DnaB_C PF03796.15 KIK56211.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 KIK56211.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family NAD_binding_5 PF07994.12 KIK56212.1 - 3.1e-139 463.9 0.0 3.6e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KIK56212.1 - 1.8e-45 153.6 0.0 3.3e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Pro_CA PF00484.19 KIK56213.1 - 5.9e-39 133.9 0.2 7.8e-39 133.5 0.2 1.2 1 0 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.16 KIK56219.1 - 1.1e-19 70.5 59.0 2e-14 53.3 43.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PITH PF06201.13 KIK56220.1 - 8e-38 130.0 2.6 9.3e-38 129.8 2.6 1.0 1 0 0 1 1 1 1 PITH domain F5_F8_type_C PF00754.25 KIK56220.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain Sad1_UNC PF07738.13 KIK56220.1 - 0.034 14.2 0.5 0.15 12.1 0.5 1.9 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal DUF4833 PF16117.5 KIK56220.1 - 0.1 12.6 0.5 8.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4833) MFS_1 PF07690.16 KIK56223.1 - 2.9e-23 82.4 52.3 6e-15 55.0 39.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK56224.1 - 3.6e-20 72.2 56.0 6.3e-12 45.1 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK56225.1 - 7.4e-21 74.4 61.9 3.6e-16 59.1 43.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK56226.1 - 1.7e-19 70.0 54.9 1.3e-15 57.2 39.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC25 PF06703.11 KIK56226.1 - 0.82 9.4 2.8 2.6 7.8 2.8 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Cpn10 PF00166.21 KIK56227.1 - 9.1e-27 93.0 0.0 1.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF905 PF06006.12 KIK56228.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) DUF3149 PF11346.8 KIK56228.1 - 0.11 12.1 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF2537 PF10801.8 KIK56228.1 - 0.17 12.2 3.6 0.48 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Metal_resist PF13801.6 KIK56228.1 - 0.22 11.7 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance CENP-F_leu_zip PF10473.9 KIK56230.1 - 0.035 14.1 1.0 0.052 13.6 1.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KIK56230.1 - 0.037 14.1 3.1 0.09 12.9 0.8 2.1 1 1 1 2 2 2 0 bZIP transcription factor DUF2828 PF11443.8 KIK56230.1 - 0.093 10.8 0.1 0.11 10.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HALZ PF02183.18 KIK56230.1 - 0.1 12.8 0.4 0.46 10.7 0.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper KLRAQ PF10205.9 KIK56230.1 - 0.18 12.0 1.0 7.9 6.8 0.1 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein bZIP_2 PF07716.15 KIK56230.1 - 0.54 10.4 2.4 0.4 10.8 0.4 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Plavaka PF18759.1 KIK56231.1 - 4.2e-16 59.1 0.1 4.2e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase NACHT PF05729.12 KIK56235.1 - 0.004 17.1 0.2 0.0063 16.4 0.2 1.3 1 0 0 1 1 1 1 NACHT domain TPR_12 PF13424.6 KIK56237.1 - 3.7e-38 129.7 23.3 2.4e-07 31.0 0.2 7.2 2 2 5 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56237.1 - 1.1e-18 65.8 22.3 0.023 14.8 0.3 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK56237.1 - 5e-13 48.3 0.0 0.49 9.9 0.0 8.4 9 0 0 9 9 9 3 SHNi-TPR SNAP PF14938.6 KIK56237.1 - 1.9e-12 47.2 2.0 3.8e-05 23.3 0.0 3.8 1 1 3 4 4 4 4 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KIK56237.1 - 4.9e-12 45.3 22.6 0.36 10.8 0.1 10.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56237.1 - 7e-10 38.8 9.8 0.0001 21.8 0.3 3.5 1 1 3 4 4 4 3 MalT-like TPR region TPR_1 PF00515.28 KIK56237.1 - 1.8e-06 27.5 13.9 5 7.1 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat OEP PF02321.18 KIK56237.1 - 9.3e-06 25.6 5.5 0.65 9.8 0.2 4.4 5 0 0 5 5 5 2 Outer membrane efflux protein TPR_8 PF13181.6 KIK56237.1 - 1.7e-05 24.7 18.5 8.8 6.8 0.2 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56237.1 - 3.4e-05 24.1 18.8 4 8.3 0.0 8.2 10 1 1 11 11 8 2 Tetratricopeptide repeat DUF3837 PF12939.7 KIK56237.1 - 0.00011 22.5 0.1 0.93 9.9 0.0 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3837) NTS PF15447.6 KIK56237.1 - 0.00062 20.2 3.1 13 6.4 0.0 7.1 9 0 0 9 9 8 0 N-terminal segments of PfEMP1 HemY_N PF07219.13 KIK56237.1 - 0.0041 17.3 10.8 3.5 7.9 0.6 5.6 5 1 2 7 7 7 2 HemY protein N-terminus DUF5495 PF17599.2 KIK56237.1 - 0.0063 16.7 0.0 4.3 7.7 0.0 3.8 3 0 0 3 3 3 1 Family of unknown function (DUF5495) TPR_16 PF13432.6 KIK56237.1 - 0.011 16.3 18.9 1.8 9.3 1.2 7.3 6 2 2 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK56237.1 - 0.026 14.7 11.9 18 5.6 0.0 6.5 2 2 4 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Tox-REase-5 PF15648.6 KIK56237.1 - 0.041 14.4 0.6 1.3e+02 3.1 0.0 5.9 7 1 0 8 8 8 0 Restriction endonuclease fold toxin 5 AbiEi_3_N PF17194.4 KIK56237.1 - 0.041 13.9 0.1 13 5.9 0.0 3.7 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Nore1-SARAH PF16517.5 KIK56237.1 - 0.099 12.6 0.0 85 3.2 0.0 4.8 6 0 0 6 6 6 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain SPECT1 PF18680.1 KIK56237.1 - 0.23 11.1 0.0 40 3.8 0.0 3.9 6 0 0 6 6 5 0 Plasmodium host cell traversal SPECT1 HTH_18 PF12833.7 KIK56237.1 - 0.28 11.5 3.6 2 8.7 0.1 3.9 5 0 0 5 5 5 0 Helix-turn-helix domain F-box PF00646.33 KIK56238.1 - 0.00042 20.1 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK56238.1 - 0.0018 18.1 1.0 0.0027 17.6 0.2 1.8 2 0 0 2 2 2 1 F-box-like TFIIA PF03153.13 KIK56238.1 - 0.0067 16.5 13.3 0.0067 16.5 13.3 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KIK56238.1 - 1 7.8 8.5 1.7 7.1 8.5 1.2 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 KIK56238.1 - 3.7 7.4 5.5 8 6.4 5.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Apt1 PF10351.9 KIK56238.1 - 9.8 4.9 7.9 21 3.8 7.9 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Transp_cyt_pur PF02133.15 KIK56239.1 - 2.3e-37 128.8 36.5 3e-37 128.4 36.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KIK56240.1 - 1.1e-41 143.0 34.5 1.5e-41 142.6 34.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fzo_mitofusin PF04799.13 KIK56240.1 - 0.33 10.5 2.6 0.72 9.4 2.6 1.6 1 0 0 1 1 1 0 fzo-like conserved region Transp_cyt_pur PF02133.15 KIK56241.1 - 2.3e-37 128.8 36.5 3e-37 128.4 36.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KIK56242.1 - 1.1e-41 143.0 34.5 1.5e-41 142.6 34.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fzo_mitofusin PF04799.13 KIK56242.1 - 0.33 10.5 2.6 0.72 9.4 2.6 1.6 1 0 0 1 1 1 0 fzo-like conserved region Transp_cyt_pur PF02133.15 KIK56243.1 - 4.2e-40 137.9 37.7 5.3e-40 137.5 37.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4014 PF13198.6 KIK56243.1 - 1.1 9.7 3.8 18 5.8 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DIOX_N PF14226.6 KIK56244.1 - 1.1e-28 100.3 0.0 2.5e-28 99.2 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK56244.1 - 4.3e-20 72.1 0.0 8.3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KIK56246.1 - 1.2e-33 116.3 0.0 3.5e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK56246.1 - 4.8e-14 52.1 0.0 1.2e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KIK56246.1 - 0.0044 17.3 0.2 0.011 16.0 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIK56246.1 - 0.061 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cellulase PF00150.18 KIK56249.1 - 2.8e-12 46.7 0.8 2.8e-12 46.7 0.8 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Amino_oxidase PF01593.24 KIK56250.1 - 1.5e-45 156.3 0.0 2.6e-45 155.6 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK56250.1 - 5.2e-10 39.4 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK56250.1 - 0.012 14.9 0.1 0.027 13.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK56250.1 - 0.029 14.9 0.2 0.097 13.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK56250.1 - 0.032 13.8 0.2 0.057 13.0 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK56250.1 - 0.037 13.3 2.4 0.069 12.4 1.9 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KIK56250.1 - 0.057 12.6 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK56250.1 - 0.3 9.7 0.2 0.52 9.0 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Cellulase PF00150.18 KIK56251.1 - 2.1e-12 47.0 0.0 2.1e-12 47.0 0.0 1.8 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 KIK56253.1 - 5e-23 82.1 0.0 7.6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK56253.1 - 1.2e-07 31.0 0.0 2.2e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF3089 PF11288.8 KIK56253.1 - 0.061 12.9 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PAE PF03283.13 KIK56253.1 - 0.3 10.2 0.6 24 3.9 0.0 2.8 2 1 1 3 3 3 0 Pectinacetylesterase MMR_HSR1 PF01926.23 KIK56255.1 - 1.5e-06 28.2 0.2 1.5e-06 28.2 0.2 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Macoilin PF09726.9 KIK56255.1 - 2.7e-05 23.0 7.8 2.9e-05 22.9 7.8 1.1 1 0 0 1 1 1 1 Macoilin family Dynamin_N PF00350.23 KIK56255.1 - 0.00054 20.1 19.7 0.023 14.8 0.9 3.9 2 2 1 3 3 3 2 Dynamin family DUF4407 PF14362.6 KIK56255.1 - 0.0022 17.4 13.7 0.0031 16.9 13.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) RsgA_GTPase PF03193.16 KIK56255.1 - 0.0042 17.0 0.1 0.0042 17.0 0.1 2.7 2 1 1 3 3 3 1 RsgA GTPase DUF812 PF05667.11 KIK56255.1 - 0.013 14.4 14.7 0.018 13.9 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Septin PF00735.18 KIK56255.1 - 0.013 14.8 0.9 0.013 14.8 0.9 2.7 2 1 0 2 2 2 0 Septin IIGP PF05049.13 KIK56255.1 - 0.032 13.3 0.2 0.032 13.3 0.2 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DivIC PF04977.15 KIK56255.1 - 0.033 14.0 3.3 0.033 14.0 3.3 3.6 2 1 2 4 4 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 KIK56255.1 - 0.034 14.4 30.1 0.2 11.9 25.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FapA PF03961.13 KIK56255.1 - 0.042 12.5 10.4 0.073 11.7 10.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fringe PF02434.16 KIK56255.1 - 0.057 12.8 2.1 0.64 9.4 0.8 2.1 2 0 0 2 2 2 0 Fringe-like FeoB_N PF02421.18 KIK56255.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KIK56255.1 - 0.091 13.1 4.9 0.22 11.9 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KIK56255.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.5 2 1 1 3 3 3 0 ABC transporter APG6_N PF17675.1 KIK56255.1 - 0.12 12.9 34.4 0.071 13.6 29.7 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Fibin PF15819.5 KIK56255.1 - 0.2 11.4 9.2 0.24 11.1 8.0 1.7 1 1 0 1 1 1 0 Fin bud initiation factor homologue AAA_22 PF13401.6 KIK56255.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain DUF4472 PF14739.6 KIK56255.1 - 0.35 11.6 25.0 0.36 11.6 19.3 2.7 1 1 2 3 3 2 0 Domain of unknown function (DUF4472) AAA_14 PF13173.6 KIK56255.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 KIK56255.1 - 1.1 8.9 13.5 3.6 7.3 13.6 1.8 2 0 0 2 2 2 0 AAA domain HCMV_UL139 PF12507.8 KIK56255.1 - 1.7 9.0 11.2 7.3 7.0 11.1 2.0 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein CorA PF01544.18 KIK56255.1 - 2.1 7.6 8.4 3.5 6.9 8.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ATP_bind_1 PF03029.17 KIK56255.1 - 2.9 7.6 6.7 7.5 6.3 0.0 3.2 2 2 1 3 3 3 0 Conserved hypothetical ATP binding protein Spc7 PF08317.11 KIK56255.1 - 3.4 6.5 25.9 2.9 6.7 24.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KIK56255.1 - 3.5 5.4 13.0 4.7 5.0 13.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.17 KIK56255.1 - 3.6 7.6 12.1 1.5 8.9 0.2 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 KIK56255.1 - 4.1 6.4 14.9 6.5 5.7 14.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 KIK56255.1 - 4.2 6.2 9.9 5.6 5.8 9.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GBP_C PF02841.14 KIK56255.1 - 5 6.4 23.2 7.1 5.9 23.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Presenilin PF01080.17 KIK56255.1 - 6.2 5.5 8.1 8.8 5.0 8.1 1.1 1 0 0 1 1 1 0 Presenilin DUF5595 PF18077.1 KIK56255.1 - 6.6 6.9 16.7 0.36 11.0 3.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) Exonuc_VII_L PF02601.15 KIK56255.1 - 7.1 6.1 11.9 13 5.3 11.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vfa1 PF08432.10 KIK56255.1 - 8.1 6.7 17.2 13 6.1 17.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.32 KIK56256.1 - 5.5e-40 134.6 11.5 9.5e-11 42.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56256.1 - 2.2e-12 47.1 0.2 0.017 15.4 0.0 4.4 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK56256.1 - 0.00091 17.9 0.1 0.038 12.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK56256.1 - 0.003 17.4 0.9 0.15 12.0 0.0 4.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK56256.1 - 0.0063 15.3 0.0 15 4.2 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KIK56256.1 - 0.0088 15.4 0.0 5.4 6.3 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KIK56256.1 - 0.018 14.0 0.0 0.15 10.9 0.0 2.7 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK56256.1 - 0.021 14.4 0.2 2.3 7.7 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KIK56256.1 - 0.026 13.2 0.1 11 4.6 0.0 3.1 2 1 0 3 3 3 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK56256.1 - 0.028 14.3 0.0 0.4 10.5 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 KIK56256.1 - 0.032 13.3 0.5 2.8 6.9 0.0 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) FlaG PF03646.15 KIK56256.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 FlaG protein PQQ_3 PF13570.6 KIK56256.1 - 0.22 12.1 2.5 5.9 7.5 0.0 4.2 5 1 0 5 5 5 0 PQQ-like domain DUF2235 PF09994.9 KIK56257.1 - 5.1e-50 170.4 0.1 6.4e-50 170.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK56258.1 - 7.3e-66 222.4 0.1 1.8e-65 221.2 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.32 KIK56258.1 - 9.5e-27 92.7 6.8 3.6e-08 33.9 0.3 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56258.1 - 1.7e-08 34.6 0.2 0.038 14.3 0.0 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIK56258.1 - 0.00054 18.8 0.1 0.44 9.2 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like FlaG PF03646.15 KIK56258.1 - 0.039 14.1 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 FlaG protein PD40 PF07676.12 KIK56258.1 - 0.048 13.6 0.0 0.99 9.4 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lipase_GDSL PF00657.22 KIK56259.1 - 5.6e-05 23.2 0.3 7.6e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK56259.1 - 5.9e-05 23.5 0.2 7.5e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HATPase_c PF02518.26 KIK56261.1 - 3.3e-20 72.7 0.0 1.9e-19 70.2 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK56261.1 - 4.9e-16 58.9 0.0 4.6e-15 55.8 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KIK56261.1 - 0.00021 21.3 0.1 0.00089 19.2 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KIK56261.1 - 0.093 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain EI24 PF07264.11 KIK56261.1 - 0.12 12.6 8.8 0.22 11.8 8.8 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1980 PF09323.10 KIK56262.1 - 0.071 13.0 0.1 0.071 13.0 0.1 2.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) MARVEL PF01284.23 KIK56262.1 - 5.9 6.9 10.5 1.2e+02 2.7 10.5 2.9 1 1 0 1 1 1 0 Membrane-associating domain MMR_HSR1 PF01926.23 KIK56264.1 - 2.3e-08 34.1 0.0 5.8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK56264.1 - 4.5e-06 26.7 0.7 0.0008 19.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KIK56264.1 - 7.6e-06 25.3 0.2 0.029 13.5 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit Septin PF00735.18 KIK56264.1 - 0.0001 21.7 0.3 0.0023 17.3 0.3 2.3 1 1 0 1 1 1 1 Septin DUF815 PF05673.13 KIK56264.1 - 0.00015 21.0 0.0 0.00033 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK56264.1 - 0.0016 18.9 0.2 0.018 15.4 0.3 2.3 1 1 1 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 KIK56264.1 - 0.007 16.2 0.3 0.25 11.1 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KIK56264.1 - 0.0087 16.6 0.7 0.029 14.9 0.2 2.0 2 1 0 2 2 2 1 ABC transporter IIGP PF05049.13 KIK56264.1 - 0.009 15.1 0.7 0.03 13.4 0.1 2.1 2 1 1 3 3 3 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KIK56264.1 - 0.01 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 KIK56264.1 - 0.013 14.8 0.5 0.093 12.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 KIK56264.1 - 0.02 15.1 0.1 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK56264.1 - 0.13 11.6 0.9 0.87 8.9 0.9 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KIK56264.1 - 0.14 12.4 0.4 0.46 10.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK56264.1 - 0.21 11.7 0.7 1.3 9.1 0.7 2.1 1 1 1 2 2 2 0 Dynamin family Jnk-SapK_ap_N PF09744.9 KIK56267.1 - 0.13 12.5 0.4 0.19 11.9 0.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ATXN-1_C PF12547.8 KIK56272.1 - 0.001 19.3 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 Capicua transcriptional repressor modulator DUF1772 PF08592.11 KIK56273.1 - 0.0018 18.6 0.1 0.0023 18.2 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Ribosomal_S4Pg PF11993.8 KIK56273.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Lsr2 PF11774.8 KIK56274.1 - 0.096 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Lsr2 Glycophorin_A PF01102.18 KIK56280.1 - 0.00083 19.6 0.4 0.0026 18.0 0.2 1.9 1 1 0 1 1 1 1 Glycophorin A Herpes_gE PF02480.16 KIK56280.1 - 0.0021 16.9 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E UNC119_bdg PF15435.6 KIK56282.1 - 0.088 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue ATXN-1_C PF12547.8 KIK56283.1 - 0.0013 19.1 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Capicua transcriptional repressor modulator KR PF08659.10 KIK56284.1 - 9.2e-05 22.4 0.0 0.00033 20.6 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KIK56284.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KIK56284.1 - 0.058 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PKcGMP_CC PF16808.5 KIK56285.1 - 0.00024 20.9 0.5 0.00024 20.9 0.5 2.3 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase ERM PF00769.19 KIK56285.1 - 0.0013 18.6 12.9 0.0024 17.7 12.9 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family RIC3 PF15361.6 KIK56285.1 - 0.0021 18.4 0.1 0.0021 18.4 0.1 2.4 2 1 1 3 3 2 1 Resistance to inhibitors of cholinesterase homologue 3 MAD PF05557.13 KIK56285.1 - 0.0026 16.2 10.1 0.0036 15.8 10.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Filament PF00038.21 KIK56285.1 - 0.0029 17.2 9.1 0.0061 16.2 9.1 1.4 1 0 0 1 1 1 1 Intermediate filament protein HIP1_clath_bdg PF16515.5 KIK56285.1 - 0.0038 17.8 18.3 0.036 14.7 10.7 2.8 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 FPP PF05911.11 KIK56285.1 - 0.005 15.1 11.9 0.0074 14.5 11.9 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil EzrA PF06160.12 KIK56285.1 - 0.014 13.7 7.6 0.02 13.1 7.6 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LMBR1 PF04791.16 KIK56285.1 - 0.029 13.3 3.0 0.049 12.5 3.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Golgin_A5 PF09787.9 KIK56285.1 - 0.041 13.3 13.4 0.079 12.4 13.4 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KIK56285.1 - 0.043 12.9 8.2 0.083 12.0 8.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31_Bap29_C PF18035.1 KIK56285.1 - 0.048 13.7 2.7 0.19 11.8 2.7 2.0 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4734 PF15881.5 KIK56285.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Fez1 PF06818.15 KIK56285.1 - 0.12 12.8 12.3 0.27 11.7 12.3 1.6 1 0 0 1 1 1 0 Fez1 HMMR_N PF15905.5 KIK56285.1 - 0.17 11.3 18.9 0.049 13.1 15.0 1.9 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KIK56285.1 - 0.19 11.9 11.6 0.41 10.8 11.6 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DASH_Duo1 PF08651.10 KIK56285.1 - 0.21 11.4 6.3 2.3 8.1 0.0 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF1192 PF06698.11 KIK56285.1 - 0.21 11.6 1.5 11 6.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Exonuc_VII_L PF02601.15 KIK56285.1 - 0.28 10.7 5.9 1.1 8.7 6.6 1.6 2 0 0 2 2 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 KIK56285.1 - 0.35 9.7 13.9 0.79 8.5 13.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein MRP-L46 PF11788.8 KIK56285.1 - 0.38 11.5 5.9 2.2 9.1 3.5 2.6 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Laminin_II PF06009.12 KIK56285.1 - 0.42 10.6 8.2 0.93 9.5 8.2 1.6 1 0 0 1 1 1 0 Laminin Domain II Phlebovirus_NSM PF07246.11 KIK56285.1 - 0.52 9.6 6.1 0.87 8.9 6.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MscS_porin PF12795.7 KIK56285.1 - 0.77 9.3 14.7 0.094 12.3 10.2 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF5082 PF16888.5 KIK56285.1 - 0.84 9.9 8.8 3.7 7.8 4.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) PEP-utilisers_N PF05524.13 KIK56285.1 - 0.89 9.7 5.0 1.4 9.1 1.4 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal OmpH PF03938.14 KIK56285.1 - 1 9.7 14.1 2.3 8.6 14.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4446 PF14584.6 KIK56285.1 - 1 9.4 8.5 1.1 9.2 1.1 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF4446) Tropomyosin_1 PF12718.7 KIK56285.1 - 1.2 9.3 23.2 0.92 9.7 18.9 2.4 2 1 0 2 2 2 0 Tropomyosin like ADIP PF11559.8 KIK56285.1 - 1.2 9.2 19.0 0.25 11.4 14.4 2.1 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KIK56285.1 - 1.9 8.9 10.0 0.18 12.1 3.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) THOC7 PF05615.13 KIK56285.1 - 2.1 8.6 11.7 91 3.3 11.7 2.6 1 1 0 1 1 1 0 Tho complex subunit 7 BEX PF04538.12 KIK56285.1 - 2.4 8.8 8.5 4.7 7.8 8.5 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family DUF4094 PF13334.6 KIK56285.1 - 2.6 8.5 6.7 0.7 10.3 0.5 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Sec8_exocyst PF04048.14 KIK56285.1 - 3.2 7.6 9.3 2.9 7.8 5.2 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.10 KIK56285.1 - 3.6 7.8 8.5 1 9.5 3.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KIK56285.1 - 3.6 6.8 7.6 6 6.1 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KIK56285.1 - 3.7 8.0 10.2 1.5 9.3 3.3 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF3552 PF12072.8 KIK56285.1 - 4.2 6.7 17.6 8.1 5.8 5.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) PspA_IM30 PF04012.12 KIK56285.1 - 4.9 6.7 16.0 2.1 7.9 2.0 2.3 1 1 1 2 2 2 0 PspA/IM30 family VPS38 PF17649.1 KIK56285.1 - 5.7 5.7 8.6 8.5 5.1 8.6 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 FHA PF00498.26 KIK56286.1 - 4e-16 59.1 0.0 5.8e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK56286.1 - 1.9e-06 28.1 0.0 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Oxidored_FMN PF00724.20 KIK56288.1 - 3.1e-68 230.6 0.0 4e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIK56288.1 - 0.022 14.5 0.1 0.063 13.0 0.1 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Mad3_BUB1_I PF08311.12 KIK56289.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 NUC153 PF08159.12 KIK56290.1 - 0.0038 17.0 0.1 4.5 7.2 0.1 2.8 2 0 0 2 2 2 2 NUC153 domain GCM PF03615.15 KIK56290.1 - 1 9.2 3.6 3.4 7.5 3.6 1.7 1 1 0 1 1 1 0 GCM motif protein Glyco_hydro_18 PF00704.28 KIK56293.1 - 7.8e-15 55.4 0.3 1.1e-14 54.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KIK56295.1 - 1.9e-14 54.1 0.1 2.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RhoGAP PF00620.27 KIK56296.1 - 0.00049 19.9 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain bZIP_1 PF00170.21 KIK56296.1 - 0.017 15.2 0.1 0.045 13.9 0.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor G6PD_C PF02781.16 KIK56297.1 - 6e-95 317.8 0.0 1.1e-94 316.9 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIK56297.1 - 6.8e-38 131.1 0.0 1e-37 130.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain NAD_binding_1 PF00175.21 KIK56298.1 - 3e-22 79.3 0.0 4.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK56298.1 - 3.4e-06 27.3 0.0 1.5e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK56298.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain GMC_oxred_N PF00732.19 KIK56299.1 - 6.9e-46 156.9 0.0 9.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK56299.1 - 8.9e-32 110.6 0.0 1.6e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK56299.1 - 0.0032 17.6 0.3 0.0074 16.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK56299.1 - 0.0052 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK56299.1 - 0.0057 15.8 0.1 0.0086 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK56299.1 - 0.018 14.2 0.5 0.031 13.4 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIK56299.1 - 0.033 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIK56299.1 - 0.034 13.4 2.8 4.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK56299.1 - 0.037 13.3 0.1 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAM83 PF07894.12 KIK56299.1 - 0.19 11.2 0.5 0.31 10.6 0.5 1.2 1 0 0 1 1 1 0 FAM83 A-H Channel_Tsx PF03502.13 KIK56299.1 - 0.25 11.1 2.0 0.3 10.8 0.2 1.8 2 0 0 2 2 2 0 Nucleoside-specific channel-forming protein, Tsx DUF4795 PF16043.5 KIK56299.1 - 0.25 10.9 1.9 0.36 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) G6PD_C PF02781.16 KIK56300.1 - 1e-05 24.9 0.0 1.2e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain CFEM PF05730.11 KIK56301.1 - 5.6e-06 26.4 12.1 9.7e-06 25.6 12.1 1.4 1 0 0 1 1 1 1 CFEM domain TIL PF01826.17 KIK56301.1 - 1.1 9.6 8.4 1.8 8.9 8.4 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF3740 PF12548.8 KIK56301.1 - 3.5 8.1 6.0 0.22 12.0 0.7 1.7 2 0 0 2 2 2 0 Sulfatase protein WW PF00397.26 KIK56302.1 - 0.0055 16.8 2.6 0.0055 16.8 2.6 2.0 2 0 0 2 2 2 1 WW domain DUF1129 PF06570.11 KIK56302.1 - 2.6 7.5 8.9 49 3.3 8.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) G-alpha PF00503.20 KIK56303.1 - 0.042 13.0 0.1 0.074 12.2 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Pput2613-deam PF14427.6 KIK56304.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Pput_2613-like deaminase DUF3489 PF11994.8 KIK56304.1 - 0.12 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) SMN PF06003.12 KIK56308.1 - 0.14 11.4 5.9 0.02 14.2 1.5 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) MMR_HSR1 PF01926.23 KIK56309.1 - 4.1e-09 36.5 0.0 8.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK56309.1 - 6.9e-07 29.3 0.1 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KIK56309.1 - 5.6e-05 22.5 4.5 0.044 12.9 1.1 2.3 2 0 0 2 2 2 2 G-protein alpha subunit DUF815 PF05673.13 KIK56309.1 - 0.00094 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KIK56309.1 - 0.0018 18.8 0.4 0.0055 17.2 0.1 1.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIK56309.1 - 0.0022 17.7 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.13 KIK56309.1 - 0.0027 16.8 0.8 0.017 14.2 0.1 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KIK56309.1 - 0.0044 16.3 1.6 0.0087 15.4 0.3 2.2 2 1 0 2 2 2 1 Septin Roc PF08477.13 KIK56309.1 - 0.0067 16.6 0.1 0.03 14.5 0.1 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KIK56309.1 - 0.0096 15.3 1.3 0.033 13.5 1.3 2.0 1 1 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 KIK56309.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KIK56309.1 - 0.012 15.7 1.4 1.9 8.5 0.5 3.2 2 1 1 3 3 3 0 Dynamin family Ras PF00071.22 KIK56309.1 - 0.031 13.9 0.8 0.9 9.1 0.1 2.7 2 1 0 2 2 2 0 Ras family AAA_22 PF13401.6 KIK56309.1 - 0.071 13.4 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIK56309.1 - 0.091 12.5 0.1 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Gtr1_RagA PF04670.12 KIK56309.1 - 0.21 10.9 3.5 0.24 10.7 1.8 2.0 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK56310.1 - 2.6e-09 37.2 0.1 8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK56310.1 - 1.1e-06 28.7 0.7 0.00032 20.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 KIK56310.1 - 3.8e-05 23.1 0.5 0.0011 18.3 0.5 2.2 1 1 0 1 1 1 1 Septin G-alpha PF00503.20 KIK56310.1 - 0.00022 20.5 3.3 0.078 12.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit DUF815 PF05673.13 KIK56310.1 - 0.0034 16.6 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IIGP PF05049.13 KIK56310.1 - 0.0042 16.2 1.5 0.0053 15.9 0.1 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK56310.1 - 0.0075 16.8 0.2 0.016 15.7 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK56310.1 - 0.0092 15.7 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 KIK56310.1 - 0.012 15.9 0.0 0.076 13.2 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK56310.1 - 0.012 16.0 0.1 0.045 14.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK56310.1 - 0.015 15.6 0.1 0.26 11.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ras PF00071.22 KIK56310.1 - 0.025 14.2 0.4 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 KIK56310.1 - 0.033 14.0 1.0 0.69 9.7 0.3 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 KIK56310.1 - 0.09 12.1 2.5 0.37 10.1 2.5 2.1 1 1 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 KIK56310.1 - 0.11 12.0 0.1 0.7 9.4 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK56310.1 - 0.16 12.0 0.8 1.2 9.2 0.8 2.2 1 1 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 KIK56311.1 - 1.7e-07 31.3 0.0 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK56311.1 - 8.2e-06 25.8 0.7 0.0012 18.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KIK56311.1 - 3.1e-05 23.3 0.2 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Septin PF00735.18 KIK56311.1 - 4.3e-05 22.9 0.3 0.00098 18.5 0.3 2.1 1 1 0 1 1 1 1 Septin AIG1 PF04548.16 KIK56311.1 - 0.0051 16.2 2.3 0.033 13.5 2.3 2.1 1 1 0 1 1 1 1 AIG1 family DUF815 PF05673.13 KIK56311.1 - 0.0051 16.0 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Roc PF08477.13 KIK56311.1 - 0.0062 16.8 0.1 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK56311.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK56311.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KIK56311.1 - 0.025 15.0 0.2 0.12 12.8 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 KIK56311.1 - 0.031 13.4 0.1 0.069 12.2 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.17 KIK56311.1 - 0.065 13.0 0.5 1.9 8.2 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KIK56311.1 - 0.073 13.1 0.3 0.4 10.7 0.3 2.1 1 1 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 KIK56311.1 - 0.15 12.4 0.0 0.99 9.7 0.0 2.4 3 1 0 3 3 3 0 AAA domain p450 PF00067.22 KIK56315.1 - 3.2e-62 210.8 0.0 3.9e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VPS9 PF02204.18 KIK56317.1 - 4.1e-31 107.3 0.1 8.3e-31 106.3 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KIK56317.1 - 4.2e-17 62.2 1.0 4.2e-17 62.2 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 KIK56317.1 - 1.6e-09 37.2 0.0 4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 KIK56317.1 - 0.00022 20.8 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif Glyco_hydro_30 PF02055.16 KIK56318.1 - 1.4e-14 53.8 1.1 1.9e-13 50.1 1.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIK56318.1 - 4.1e-12 46.0 0.1 7.4e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 GPI-anchored PF10342.9 KIK56320.1 - 1.9e-09 38.1 5.2 1.9e-09 38.1 5.2 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DDE_Tnp_1_2 PF13586.6 KIK56321.1 - 0.22 11.9 4.4 0.16 12.3 1.4 2.0 1 1 1 2 2 2 0 Transposase DDE domain Apolipoprotein PF01442.18 KIK56321.1 - 0.27 11.1 9.1 0.49 10.2 9.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-HC5HC2H_2 PF13832.6 KIK56322.1 - 1.6e-32 111.9 13.9 1.1e-31 109.3 9.2 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KIK56322.1 - 7.5e-25 88.1 2.1 7.5e-25 88.1 2.1 3.2 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KIK56322.1 - 5.7e-23 81.0 6.4 5.7e-23 81.0 6.4 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KIK56322.1 - 3.4e-19 68.7 0.1 1e-18 67.2 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KIK56322.1 - 9.6e-15 53.9 3.0 9.6e-15 53.9 3.0 2.8 3 0 0 3 3 3 1 PHD-finger PWWP PF00855.17 KIK56322.1 - 4.2e-12 46.3 2.2 4.2e-12 46.3 2.2 2.4 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 KIK56322.1 - 1.5e-10 40.8 5.7 1.5e-10 40.8 5.7 3.1 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 KIK56322.1 - 0.003 17.2 0.8 0.003 17.2 0.8 2.9 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KIK56322.1 - 0.0072 16.2 0.5 0.0072 16.2 0.5 2.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIK56322.1 - 8.2 6.8 16.6 0.46 10.8 2.0 2.8 3 0 0 3 3 3 0 C1 domain p450 PF00067.22 KIK56323.1 - 3.8e-50 171.0 0.0 5.4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FerI PF08151.12 KIK56325.1 - 0.2 11.8 2.6 0.18 11.9 0.4 2.2 2 1 0 2 2 2 0 FerI (NUC094) domain Tub_N PF16322.5 KIK56325.1 - 0.96 9.8 9.5 1.3 9.4 9.5 1.2 1 0 0 1 1 1 0 Tubby N-terminal Methyltransf_2 PF00891.18 KIK56327.1 - 1.5e-20 73.4 0.0 7.9e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KIK56327.1 - 0.077 13.7 0.0 0.21 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK56327.1 - 0.12 13.0 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HD PF01966.22 KIK56330.1 - 6.1e-11 42.6 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KIK56330.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 HDOD domain LRR_4 PF12799.7 KIK56332.1 - 0.11 13.0 0.1 2.7 8.5 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) GST_N_3 PF13417.6 KIK56333.1 - 1.6e-11 44.5 0.0 4.7e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK56333.1 - 3e-10 40.2 0.0 6.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK56333.1 - 0.078 13.3 0.0 23 5.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIK56333.1 - 0.078 13.7 0.0 4.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain DUF3727 PF12527.8 KIK56333.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) GST_N_3 PF13417.6 KIK56334.1 - 2.4e-11 43.9 0.0 6.5e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK56334.1 - 1.1e-09 38.4 0.0 2.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIK56334.1 - 0.038 14.7 0.0 5.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KIK56334.1 - 0.16 12.4 0.0 2.8 8.3 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GFA PF04828.14 KIK56335.1 - 8.5e-07 29.2 0.7 1.5e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme ICMT PF04140.14 KIK56336.1 - 4.4e-12 46.3 3.0 9.5e-12 45.2 0.1 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK56336.1 - 7.7e-12 45.5 0.2 2.5e-09 37.5 0.2 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK56336.1 - 2.1e-05 23.5 0.1 3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK56336.1 - 0.0016 18.0 0.4 0.0034 16.9 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) HECT PF00632.25 KIK56337.1 - 1.3e-94 317.1 0.0 1.8e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KIK56337.1 - 0.0065 16.2 0.2 0.0065 16.2 0.2 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Aldo_ket_red PF00248.21 KIK56338.1 - 6.3e-45 153.6 0.0 7.1e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.6 KIK56340.1 - 7.1e-06 25.6 0.7 2e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 KIK56340.1 - 0.0048 16.7 1.6 0.053 13.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK56340.1 - 0.007 17.0 0.3 0.007 17.0 0.3 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56340.1 - 0.0084 16.2 2.7 0.093 12.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat BAALC_N PF06989.12 KIK56340.1 - 0.058 13.7 1.8 6 7.3 0.2 2.5 2 0 0 2 2 2 0 BAALC N-terminus TPR_17 PF13431.6 KIK56340.1 - 0.073 13.5 0.0 0.82 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuc_P_40 PF08584.11 KIK56341.1 - 5.3e-31 108.0 0.0 7.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit HMG_CoA_synt_C PF08540.10 KIK56342.1 - 1.9e-87 293.5 0.4 2.3e-87 293.2 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KIK56342.1 - 2.6e-86 287.9 0.1 3.7e-86 287.4 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 KIK56342.1 - 0.072 13.0 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3641 PF12345.8 KIK56342.1 - 0.12 12.4 0.0 22 5.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3641) ACP_syn_III_C PF08541.10 KIK56342.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FA_desaturase PF00487.24 KIK56344.1 - 0.48 10.2 3.6 0.7 9.7 3.6 1.4 1 0 0 1 1 1 0 Fatty acid desaturase RNA_ligase PF09414.10 KIK56345.1 - 1.5e-30 106.6 0.1 2.6e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 KIK56345.1 - 4e-09 36.8 0.1 0.0026 17.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain Y_phosphatase PF00102.27 KIK56345.1 - 9e-07 28.7 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KIK56345.1 - 2.3e-05 24.5 0.0 8.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIK56345.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KIK56345.1 - 0.0028 17.5 0.0 0.0087 15.9 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KIK56345.1 - 0.0084 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate AAA_16 PF13191.6 KIK56345.1 - 0.1 13.0 0.1 14 6.0 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AAA_5 PF07728.14 KIK56345.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK56345.1 - 0.15 12.3 0.0 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIK56345.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1752 PF08550.10 KIK56347.1 - 7.2e-09 35.3 9.0 2.1e-08 33.9 9.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 KIK56348.1 - 1.3e-19 70.4 19.8 1.3e-19 70.4 19.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Cir_N PF10197.9 KIK56349.1 - 1.3e-06 28.5 0.3 1.3e-06 28.5 0.3 2.5 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF5112 PF17139.4 KIK56349.1 - 0.11 12.0 1.0 0.18 11.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) CWC25 PF12542.8 KIK56349.1 - 7.1 7.6 9.9 48 4.9 9.9 2.5 1 1 0 1 1 1 0 Pre-mRNA splicing factor GFA PF04828.14 KIK56350.1 - 4.3e-10 39.8 0.6 7.5e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 KIK56350.1 - 0.012 15.5 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-H2C2_5 PF13909.6 KIK56351.1 - 2.7e-09 36.6 2.7 4.8e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK56351.1 - 6.6e-07 29.5 6.8 0.0062 16.9 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK56351.1 - 0.078 13.9 11.2 0.56 11.2 0.4 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 KIK56351.1 - 0.094 12.7 0.0 6.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf_C2H2_ZHX PF18387.1 KIK56351.1 - 0.1 12.3 0.9 0.89 9.3 0.0 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Myc-LZ PF02344.15 KIK56352.1 - 1.6 8.9 12.3 0.74 10.0 5.8 3.0 3 0 0 3 3 3 0 Myc leucine zipper domain V-SNARE PF05008.15 KIK56353.1 - 5.8e-19 68.3 7.4 7.7e-19 67.8 2.5 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIK56353.1 - 3.3e-13 49.7 4.7 3.3e-13 49.7 4.7 2.1 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 KIK56353.1 - 0.0011 17.1 2.6 0.036 12.0 0.3 2.0 2 0 0 2 2 2 2 Prominin DUF2207 PF09972.9 KIK56353.1 - 0.021 13.6 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec20 PF03908.13 KIK56353.1 - 0.022 14.7 1.3 0.028 14.3 0.1 1.8 2 0 0 2 2 2 0 Sec20 Synaptobrevin PF00957.21 KIK56353.1 - 0.054 13.3 2.0 0.081 12.7 0.7 1.9 2 0 0 2 2 2 0 Synaptobrevin YqjK PF13997.6 KIK56353.1 - 0.11 12.8 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 YqjK-like protein Plasmid_RAQPRD PF09686.10 KIK56353.1 - 0.16 12.2 6.6 0.57 10.4 0.2 3.0 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Tropomyosin_1 PF12718.7 KIK56353.1 - 0.24 11.5 4.0 0.43 10.7 1.1 2.0 2 0 0 2 2 2 0 Tropomyosin like T3SS_needle_E PF08988.10 KIK56353.1 - 0.52 10.5 5.2 27 5.0 0.1 3.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle SNARE PF05739.19 KIK56353.1 - 3.7 7.6 5.8 13 5.8 5.8 2.1 1 1 0 1 1 1 0 SNARE domain DUF4953 PF16313.5 KIK56354.1 - 0.0021 17.3 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Met-zincin LEDGF PF11467.8 KIK56354.1 - 0.02 14.5 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) FUSC PF04632.12 KIK56354.1 - 0.073 11.6 0.6 0.088 11.3 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 KIK56354.1 - 0.12 12.6 0.2 2.7 8.3 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Sigma70_r3 PF04539.16 KIK56354.1 - 0.13 12.4 0.3 0.13 12.4 0.3 2.6 3 1 1 4 4 4 0 Sigma-70 region 3 PAH PF02671.21 KIK56354.1 - 0.23 11.6 0.3 2.7 8.2 0.2 2.2 2 0 0 2 2 2 0 Paired amphipathic helix repeat Rx_N PF18052.1 KIK56354.1 - 0.31 11.3 2.5 0.56 10.5 0.8 2.1 1 1 1 2 2 2 0 Rx N-terminal domain PDDEXK_6 PF04720.12 KIK56354.1 - 0.7 9.8 3.8 0.7 9.8 2.7 1.4 1 1 1 2 2 2 0 PDDEXK-like family of unknown function Nop14 PF04147.12 KIK56355.1 - 7.4e-296 984.0 11.5 9.1e-296 983.7 11.5 1.1 1 0 0 1 1 1 1 Nop14-like family PACT_coil_coil PF10495.9 KIK56356.1 - 7.5e-16 58.5 0.7 7.5e-16 58.5 0.7 5.1 5 0 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Aurora-A_bind PF09041.10 KIK56356.1 - 0.0027 17.7 0.2 0.0083 16.2 0.2 1.9 1 0 0 1 1 1 1 Aurora-A binding Laminin_II PF06009.12 KIK56356.1 - 0.027 14.5 0.4 0.027 14.5 0.4 10.4 5 2 6 11 11 11 0 Laminin Domain II DUF5340 PF17275.2 KIK56356.1 - 3 8.1 0.0 3 8.1 0.0 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5340) DUF5403 PF17395.2 KIK56356.1 - 7 7.0 6.0 4.2 7.7 0.4 3.6 2 1 1 3 3 3 0 Family of unknown function (DUF5403) CDP-OH_P_transf PF01066.21 KIK56357.1 - 5.7e-14 52.6 0.4 5.7e-14 52.6 0.4 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF5632 PF18646.1 KIK56357.1 - 0.075 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5632) AAA_16 PF13191.6 KIK56358.1 - 0.092 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RHSP PF07999.11 KIK56358.1 - 0.099 11.4 0.0 3.9 6.2 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon hot spot protein FtsK_SpoIIIE PF01580.18 KIK56358.1 - 0.13 11.5 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KIK56358.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KIK56358.1 - 0.19 11.4 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK56358.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein F-box-like PF12937.7 KIK56360.1 - 1.7e-09 37.4 1.3 1.7e-09 37.4 1.3 2.3 2 0 0 2 2 2 1 F-box-like zf-C2H2 PF00096.26 KIK56362.1 - 1.1e-06 28.8 9.2 0.031 14.7 0.2 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIK56362.1 - 0.0016 18.1 3.7 0.029 14.1 0.4 3.7 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIK56362.1 - 0.0035 18.0 10.4 0.7 10.9 0.2 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KIK56362.1 - 0.013 14.9 0.5 0.7 9.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KIK56362.1 - 0.34 10.9 3.4 19 5.3 0.6 3.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L5_C PF00673.21 KIK56363.1 - 1.9e-21 76.0 0.0 3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KIK56363.1 - 2.2e-21 75.9 0.1 5.4e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 zf-H2C2_5 PF13909.6 KIK56365.1 - 0.0013 18.4 7.3 0.1 12.4 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK56365.1 - 0.02 15.4 0.8 0.02 15.4 0.8 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK56365.1 - 0.27 11.7 8.8 7.1 7.2 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-TRAF PF02176.18 KIK56365.1 - 0.37 11.5 2.3 0.68 10.7 2.3 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_4 PF13894.6 KIK56365.1 - 5 8.2 9.3 5.5 8.1 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ArAE_2 PF10334.9 KIK56368.1 - 0.0024 17.7 0.6 0.09 12.6 0.4 2.1 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 KDZ PF18758.1 KIK56369.1 - 4.6e-07 29.7 0.7 5.2e-07 29.5 0.7 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Glyco_transf_25 PF01755.17 KIK56369.1 - 0.15 11.9 0.5 0.3 10.9 0.3 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) CxC4 PF18717.1 KIK56370.1 - 6.6e-45 152.2 0.1 2e-44 150.6 0.1 1.7 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases zf-TFIIB PF13453.6 KIK56370.1 - 0.0095 15.3 1.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor zinc-finger MCC-bdg_PDZ PF10506.9 KIK56375.1 - 0.13 12.3 1.9 8.2 6.5 2.2 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome zf-MYND PF01753.18 KIK56376.1 - 0.045 13.9 2.0 0.083 13.0 2.0 1.4 1 0 0 1 1 1 0 MYND finger Alpha_kinase PF02816.18 KIK56380.1 - 1.3e-23 84.1 0.0 2.5e-23 83.2 0.0 1.4 2 0 0 2 2 2 1 Alpha-kinase family TACC_C PF05010.14 KIK56383.1 - 0.00029 20.7 18.7 0.00029 20.7 18.7 2.4 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ISG65-75 PF11727.8 KIK56383.1 - 1 8.5 23.2 0.84 8.8 5.3 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Fez1 PF06818.15 KIK56383.1 - 2.2 8.7 42.7 0.63 10.5 24.6 2.3 1 1 1 2 2 2 0 Fez1 YlqD PF11068.8 KIK56383.1 - 5.8 7.3 32.4 14 6.1 11.6 3.8 1 1 2 3 3 3 0 YlqD protein Spc7 PF08317.11 KIK56383.1 - 7 5.4 42.1 1.7 7.5 15.1 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein MCPsignal PF00015.21 KIK56383.1 - 9.4 6.0 15.1 0.21 11.4 2.5 2.8 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRR_4 PF12799.7 KIK56385.1 - 0.065 13.7 0.0 0.93 10.0 0.0 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Macoilin PF09726.9 KIK56386.1 - 3.6 6.0 5.8 4.4 5.7 5.8 1.1 1 0 0 1 1 1 0 Macoilin family MBD PF01429.19 KIK56388.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain NMO PF03060.15 KIK56390.1 - 3.1e-48 164.9 0.1 4.5e-48 164.4 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK56390.1 - 9.4e-07 28.1 0.0 8.2e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK56390.1 - 0.12 11.4 0.5 0.19 10.7 0.5 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase zf-UBR PF02207.20 KIK56391.1 - 4.9e-17 61.9 14.7 4.9e-17 61.9 14.7 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KIK56391.1 - 3.4e-11 42.8 0.1 8.3e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 KIK56391.1 - 0.0044 16.6 0.1 0.0082 15.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL UPF0300 PF08594.10 KIK56391.1 - 0.096 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) zf-RING_UBOX PF13445.6 KIK56392.1 - 2.5e-08 33.8 6.8 2.5e-08 33.8 6.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK56392.1 - 2.8e-08 33.5 7.3 4.6e-08 32.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK56392.1 - 6.4e-07 29.1 10.0 1.1e-06 28.4 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK56392.1 - 1.5e-06 28.4 10.0 2.6e-06 27.7 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK56392.1 - 9.9e-06 25.4 9.8 1.8e-05 24.6 9.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK56392.1 - 1.5e-05 25.0 10.9 2.5e-05 24.4 10.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK56392.1 - 3.5e-05 23.5 11.7 8.5e-05 22.3 11.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK56392.1 - 0.00066 19.5 10.3 0.0013 18.5 10.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KIK56392.1 - 0.00072 19.2 8.5 0.0018 18.0 3.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger Filament PF00038.21 KIK56392.1 - 0.0025 17.5 4.7 0.0025 17.5 4.7 1.4 1 1 0 1 1 1 1 Intermediate filament protein zf-RING_4 PF14570.6 KIK56392.1 - 0.0061 16.3 4.4 0.015 15.1 4.4 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Sec8_exocyst PF04048.14 KIK56392.1 - 0.0077 16.1 0.3 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain MbeD_MobD PF04899.12 KIK56392.1 - 0.04 14.0 10.6 1.9 8.7 0.4 3.4 1 1 2 3 3 3 0 MbeD/MobD like zf-RING_6 PF14835.6 KIK56392.1 - 0.18 11.7 10.5 0.43 10.5 10.5 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Tweety PF04906.13 KIK56392.1 - 0.25 10.0 1.2 0.32 9.6 1.2 1.1 1 0 0 1 1 1 0 Tweety V_ATPase_I PF01496.19 KIK56392.1 - 0.56 8.0 4.6 0.67 7.8 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 KIK56392.1 - 0.58 10.9 8.7 0.21 12.3 1.6 2.2 1 1 1 2 2 2 0 Occludin homology domain Med9 PF07544.13 KIK56392.1 - 0.76 9.9 4.1 1.3 9.2 0.1 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.15 KIK56392.1 - 1.6 8.2 5.9 2 7.9 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KIK56392.1 - 3.1 8.2 8.1 1.6 9.1 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein FYVE PF01363.21 KIK56392.1 - 3.1 8.0 12.3 1.5 9.0 8.3 2.5 3 1 1 4 4 4 0 FYVE zinc finger zf-C4pol PF14260.6 KIK56392.1 - 9.9 6.7 9.7 1.3e+02 3.1 0.3 4.2 2 2 2 5 5 5 0 C4-type zinc-finger of DNA polymerase delta zf-C3HC4_3 PF13920.6 KIK56394.1 - 3.6e-08 33.1 16.7 3.6e-08 33.1 16.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.12 KIK56394.1 - 0.01 15.3 4.2 0.014 14.9 4.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK56394.1 - 0.6 8.3 11.4 0.78 7.9 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family Prok-RING_4 PF14447.6 KIK56394.1 - 3.5 7.6 21.8 0.095 12.6 14.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 G0-G1_switch_2 PF15103.6 KIK56396.1 - 0.059 13.8 0.1 0.072 13.5 0.1 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 TRAP_alpha PF03896.16 KIK56396.1 - 0.095 11.9 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ATP_bind_2 PF03668.15 KIK56397.1 - 0.23 10.7 0.0 0.27 10.5 0.0 1.0 1 0 0 1 1 1 0 P-loop ATPase protein family GPW_gp25 PF04965.14 KIK56399.1 - 0.0083 15.9 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme zf-C2H2_6 PF13912.6 KIK56402.1 - 0.025 14.6 0.9 0.051 13.6 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Sec8_exocyst PF04048.14 KIK56404.1 - 0.038 13.9 1.0 3.6 7.5 0.0 2.9 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain F-box PF00646.33 KIK56405.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF2675 PF11247.8 KIK56405.1 - 0.18 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) Mod_r PF07200.13 KIK56406.1 - 0.048 13.8 0.8 1.7 8.8 0.1 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CxC4 PF18717.1 KIK56410.1 - 2.1e-46 157.0 0.0 4.8e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK56410.1 - 0.0015 18.2 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MUG113 PF13455.6 KIK56411.1 - 0.00025 21.7 0.0 0.00096 19.8 0.0 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK56411.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain APC_u14 PF16635.5 KIK56413.1 - 0.077 13.5 0.2 0.09 13.3 0.2 1.1 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr Orf78 PF06024.12 KIK56413.1 - 0.11 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) AMP-binding PF00501.28 KIK56414.1 - 1.8e-84 283.8 0.0 2.4e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK56414.1 - 1.3e-13 51.7 0.6 2.7e-13 50.7 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4620 PF15399.6 KIK56414.1 - 0.0029 17.9 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4620) Hydantoinase_A PF01968.18 KIK56415.1 - 1.7e-77 260.5 0.0 2.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Lipase_3 PF01764.25 KIK56415.1 - 4.3e-13 49.3 0.0 9.2e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydant_A_N PF05378.13 KIK56415.1 - 1.3e-08 34.8 0.0 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region PGAP1 PF07819.13 KIK56415.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIK56415.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK56415.1 - 0.034 14.7 0.1 0.073 13.7 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK56417.1 - 6.5e-21 75.1 0.0 6.3e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK56417.1 - 1.9e-16 61.3 9.4 3.3e-15 57.3 9.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK56417.1 - 6.5e-11 42.0 0.0 6.3e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 KIK56417.1 - 0.0029 18.0 0.2 0.006 16.9 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Esterase PF00756.20 KIK56417.1 - 0.0083 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Cellulase PF00150.18 KIK56417.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Ndr PF03096.14 KIK56417.1 - 0.12 11.0 0.0 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Ndr family Hydant_A_N PF05378.13 KIK56419.1 - 2.4e-21 76.3 0.0 2.6e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region VraX PF17412.2 KIK56424.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function Otopetrin PF03189.13 KIK56425.1 - 0.016 14.0 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Imm_superinfect PF14373.6 KIK56426.1 - 0.14 12.1 4.1 0.36 10.8 4.1 1.7 1 0 0 1 1 1 0 Superinfection immunity protein TRAM1 PF08390.11 KIK56427.1 - 0.078 12.6 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 TRAM1-like protein zf-C3HC4_3 PF13920.6 KIK56428.1 - 1.5e-10 40.8 6.4 2.6e-10 40.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK56428.1 - 2.4e-08 34.2 9.2 4.4e-08 33.3 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK56428.1 - 3.5e-08 33.2 10.8 6.7e-08 32.3 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK56428.1 - 1.4e-07 31.5 5.5 1.4e-07 31.5 5.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK56428.1 - 4.6e-07 29.9 13.7 4.6e-07 29.9 13.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK56428.1 - 3.8e-06 26.6 12.0 4.2e-06 26.5 10.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK56428.1 - 3.9e-06 26.6 9.0 9e-06 25.5 9.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK56428.1 - 4.6e-05 23.3 8.8 9.4e-05 22.3 8.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIK56428.1 - 0.0016 18.6 4.6 0.0035 17.6 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIK56428.1 - 0.0059 16.5 12.9 0.038 13.8 12.9 2.1 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KIK56428.1 - 0.012 15.4 5.5 0.026 14.3 5.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain T3SSipB PF16535.5 KIK56428.1 - 0.1 13.0 7.4 0.22 12.0 7.4 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF4407 PF14362.6 KIK56428.1 - 0.16 11.3 5.5 0.22 10.8 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KIK56428.1 - 0.18 10.7 9.4 0.24 10.2 9.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_11 PF17123.5 KIK56428.1 - 0.73 9.6 8.1 1.6 8.6 8.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger ADIP PF11559.8 KIK56428.1 - 2.2 8.3 15.6 1.1 9.3 10.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Syntaxin_2 PF14523.6 KIK56428.1 - 3.1 8.2 7.5 3.2 8.2 3.9 2.1 1 1 1 2 2 2 0 Syntaxin-like protein FYVE PF01363.21 KIK56428.1 - 3.7 7.8 11.0 7.6 6.8 7.9 2.7 2 1 1 3 3 3 0 FYVE zinc finger TMF_TATA_bd PF12325.8 KIK56428.1 - 4.9 7.4 13.7 5.9 7.1 6.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DZR PF12773.7 KIK56428.1 - 7.9 6.6 10.2 71 3.5 10.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon FlaF PF07309.11 KIK56429.1 - 0.0094 15.9 1.2 0.022 14.8 1.2 1.6 1 0 0 1 1 1 1 Flagellar protein FlaF DEK_C PF08766.11 KIK56429.1 - 0.021 14.7 0.2 0.084 12.8 0.2 2.1 1 1 0 1 1 1 0 DEK C terminal domain RHSP PF07999.11 KIK56430.1 - 0.11 11.2 0.1 7 5.3 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon hot spot protein Glyco_hydro_35 PF01301.19 KIK56431.1 - 9.8e-72 242.2 0.3 1.5e-71 241.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIK56431.1 - 2.3e-49 166.7 1.6 1.7e-28 99.5 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIK56431.1 - 1.6e-46 158.4 3.4 2.4e-46 157.8 3.4 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIK56431.1 - 3.5e-20 71.4 0.0 8.5e-20 70.1 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KIK56431.1 - 0.0002 20.9 0.2 0.00049 19.6 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Gifsy-2 PF13856.6 KIK56431.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage GFA PF04828.14 KIK56432.1 - 3e-07 30.7 0.6 7.2e-07 29.5 0.0 1.9 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_35 PF01301.19 KIK56433.1 - 1.4e-74 251.6 0.4 2e-74 251.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIK56433.1 - 1.4e-50 170.7 2.7 9.7e-30 103.5 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIK56433.1 - 9.3e-46 155.9 4.2 1.8e-45 155.0 4.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIK56433.1 - 9.6e-23 79.6 0.5 2.9e-22 78.0 0.2 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KIK56433.1 - 0.062 12.7 0.1 0.21 11.0 0.0 1.8 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) ESCRT-II PF05871.12 KIK56434.1 - 9.7e-33 113.4 0.2 1.3e-32 113.0 0.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit HATPase_c PF02518.26 KIK56435.1 - 1.8e-23 83.2 0.2 3.4e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK56435.1 - 1.3e-17 63.9 0.1 9.1e-17 61.3 0.1 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KIK56435.1 - 1.8e-07 31.1 0.0 1.2e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KIK56435.1 - 0.0044 16.9 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Joubert PF15392.6 KIK56435.1 - 0.11 12.1 4.4 0.23 11.2 4.4 1.4 1 0 0 1 1 1 0 Joubert syndrome-associated zf-C3HC4_3 PF13920.6 KIK56436.1 - 4.4e-08 32.9 5.0 1.4e-07 31.2 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK56436.1 - 3.2e-06 27.3 6.0 3.2e-06 27.3 6.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIK56436.1 - 3.4e-06 26.8 5.0 3.4e-06 26.8 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK56436.1 - 3.5e-06 26.9 8.9 3.5e-06 26.9 8.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK56436.1 - 0.00015 21.5 8.8 0.00028 20.7 6.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK56436.1 - 0.00047 20.0 4.8 0.0012 18.6 4.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK56436.1 - 0.00065 19.7 3.0 0.00065 19.7 3.0 2.6 2 2 1 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.6 KIK56436.1 - 0.0015 18.3 5.9 0.0059 16.4 5.9 2.1 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIK56436.1 - 0.0081 16.3 10.8 0.06 13.5 6.6 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KIK56436.1 - 0.035 13.8 2.6 0.18 11.6 1.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger Baculo_IE-1 PF05290.11 KIK56436.1 - 0.41 10.6 5.2 0.53 10.2 4.1 1.7 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Aldo_ket_red PF00248.21 KIK56438.1 - 1.9e-44 152.1 0.0 2.1e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ESCRT-II PF05871.12 KIK56438.1 - 0.011 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit Aldo_ket_red PF00248.21 KIK56439.1 - 2.8e-46 158.1 0.0 3.3e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ESCRT-II PF05871.12 KIK56439.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit ABC_membrane PF00664.23 KIK56442.1 - 7.5e-78 261.9 26.8 1.2e-43 149.7 8.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK56442.1 - 1e-61 207.5 0.0 6.6e-34 117.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK56442.1 - 1.8e-14 54.3 0.1 0.00077 19.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK56442.1 - 8.7e-14 51.5 0.0 1.6e-05 24.5 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK56442.1 - 9.7e-09 35.8 0.8 0.0018 18.7 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KIK56442.1 - 2.5e-06 27.1 1.4 0.052 13.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK56442.1 - 9.6e-06 25.5 0.0 0.21 11.3 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK56442.1 - 1.1e-05 25.4 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KIK56442.1 - 1.8e-05 24.4 0.0 1.3 8.5 0.0 3.9 4 0 0 4 4 3 2 AAA domain DUF87 PF01935.17 KIK56442.1 - 8.8e-05 22.7 0.1 0.29 11.2 0.0 2.8 3 0 0 3 3 2 2 Helicase HerA, central domain IstB_IS21 PF01695.17 KIK56442.1 - 0.00027 20.7 0.0 8.7 6.0 0.0 4.2 4 1 0 4 4 4 0 IstB-like ATP binding protein AAA_5 PF07728.14 KIK56442.1 - 0.00037 20.5 0.1 0.26 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KIK56442.1 - 0.00049 20.3 1.0 0.52 10.6 0.1 4.0 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KIK56442.1 - 0.0005 20.4 3.1 0.2 11.9 0.1 3.8 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK56442.1 - 0.00053 19.8 1.3 0.13 12.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK56442.1 - 0.00069 20.2 0.1 0.12 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIK56442.1 - 0.00087 18.6 0.5 0.16 11.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ATP-synt_ab PF00006.25 KIK56442.1 - 0.0012 18.6 0.1 0.058 13.0 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 KIK56442.1 - 0.0013 19.3 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KIK56442.1 - 0.0016 18.2 0.1 0.96 9.1 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIK56442.1 - 0.0028 17.1 0.6 0.21 11.0 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIK56442.1 - 0.003 17.5 1.1 1.1 9.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain TniB PF05621.11 KIK56442.1 - 0.0039 16.6 0.4 4.4 6.7 0.0 3.7 4 0 0 4 4 3 0 Bacterial TniB protein AAA_33 PF13671.6 KIK56442.1 - 0.0041 17.3 0.2 3.9 7.6 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA PF00004.29 KIK56442.1 - 0.0058 17.0 0.0 1.3 9.4 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KIK56442.1 - 0.0076 16.0 0.6 0.18 11.5 0.1 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DEAD PF00270.29 KIK56442.1 - 0.0082 15.9 0.2 5.9 6.6 0.0 3.3 2 2 0 2 2 2 0 DEAD/DEAH box helicase APS_kinase PF01583.20 KIK56442.1 - 0.012 15.5 0.1 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK56442.1 - 0.013 15.8 0.2 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 KIK56442.1 - 0.015 14.5 0.2 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit DUF2721 PF11026.8 KIK56442.1 - 0.017 15.0 0.0 0.017 15.0 0.0 3.2 3 0 0 3 3 1 0 Protein of unknown function (DUF2721) NB-ARC PF00931.22 KIK56442.1 - 0.017 14.3 0.4 0.3 10.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KIK56442.1 - 0.021 15.1 1.4 0.23 11.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK56442.1 - 0.051 12.7 0.2 0.62 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KIK56442.1 - 0.078 13.1 1.9 3.1 7.9 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 KIK56442.1 - 0.098 12.6 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Sigma54_activ_2 PF14532.6 KIK56442.1 - 0.11 12.6 0.2 4.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIK56442.1 - 0.12 11.9 0.1 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KIK56442.1 - 0.2 10.2 0.0 3 6.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KIK56442.1 - 0.23 11.7 0.3 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KIK56442.1 - 0.28 10.9 0.3 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIK56442.1 - 0.35 10.2 1.9 13 5.0 0.0 2.6 3 0 0 3 3 2 0 KaiC AbrB_C PF18277.1 KIK56443.1 - 0.11 12.1 0.1 0.67 9.6 0.0 2.1 3 0 0 3 3 3 0 AbrB C-terminal domain Carb_bind PF10645.9 KIK56444.1 - 1.9e-33 114.4 24.7 3.2e-18 65.7 7.2 2.2 2 0 0 2 2 2 2 Carbohydrate binding Metallothio_6 PF05522.11 KIK56444.1 - 0.00028 21.3 5.0 0.0027 18.2 0.5 2.2 2 0 0 2 2 2 2 Metallothionein IGFL PF14653.6 KIK56444.1 - 0.83 9.7 16.0 2.1 8.4 1.2 3.3 1 1 2 3 3 3 0 Insulin growth factor-like family QH-AmDH_gamma PF08992.11 KIK56444.1 - 4.2 7.4 7.7 12 6.0 0.0 3.4 2 1 2 4 4 4 0 Quinohemoprotein amine dehydrogenase, gamma subunit zf-tcix PF14952.6 KIK56444.1 - 6.9 6.4 9.7 8.5 6.1 1.6 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Leader_CPA1 PF08252.11 KIK56444.1 - 8.1 5.9 19.0 1.5 8.3 0.6 3.5 3 0 0 3 3 3 0 arg-2/CPA1 leader peptide Hydantoinase_A PF01968.18 KIK56445.1 - 8.3e-95 317.4 0.0 1.6e-94 316.5 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIK56445.1 - 3e-57 193.2 0.2 2.6e-54 183.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF572 PF04502.13 KIK56446.1 - 0.077 12.6 9.5 0.12 12.0 9.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mac PF12464.8 KIK56446.1 - 0.53 10.6 4.0 2.7 8.3 2.4 2.6 1 1 1 2 2 2 0 Maltose acetyltransferase ADH_N_2 PF16884.5 KIK56447.1 - 3.4e-21 75.1 0.0 8.9e-21 73.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIK56447.1 - 2.8e-18 66.1 0.0 5e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK56447.1 - 2.7e-07 31.7 0.0 6.5e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK56447.1 - 0.041 14.1 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 KIK56447.1 - 0.059 13.1 0.4 0.093 12.4 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2855 PF11017.8 KIK56447.1 - 0.066 12.9 0.2 0.88 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) zf-CHY PF05495.12 KIK56448.1 - 1.2e-10 41.7 16.5 1.8e-10 41.2 16.5 1.3 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_12 PF11331.8 KIK56448.1 - 0.012 15.4 4.0 1.5 8.7 0.0 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain IL6 PF00489.17 KIK56448.1 - 0.023 14.3 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family zf-H2C2_5 PF13909.6 KIK56449.1 - 1.8e-07 30.8 9.8 0.0015 18.2 2.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK56449.1 - 8e-07 29.2 9.3 0.012 16.0 0.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK56449.1 - 3.5e-06 27.4 6.8 0.3 12.0 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK56449.1 - 0.00012 22.3 13.3 0.00059 20.1 0.3 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KIK56449.1 - 0.015 15.6 7.0 2.7 8.4 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding gag_pre-integrs PF13976.6 KIK56449.1 - 0.086 12.7 2.7 0.19 11.6 0.6 2.3 2 0 0 2 2 2 0 GAG-pre-integrase domain OrsD PF12013.8 KIK56449.1 - 0.93 10.0 6.6 30 5.1 0.1 3.4 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zn-ribbon_8 PF09723.10 KIK56449.1 - 4.4 7.5 6.7 5.3 7.2 0.2 2.5 2 1 0 2 2 2 0 Zinc ribbon domain IBR PF01485.21 KIK56449.1 - 4.5 7.6 7.3 1.4 9.2 3.6 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-H2C2_5 PF13909.6 KIK56450.1 - 1.5e-07 31.0 8.0 0.0011 18.7 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK56450.1 - 1.6e-06 28.2 8.1 0.035 14.6 0.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK56450.1 - 1.8e-06 28.3 6.0 0.59 11.1 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK56450.1 - 2.3e-05 24.6 0.1 2.3e-05 24.6 0.1 4.4 5 0 0 5 5 5 1 Zinc-finger double domain zf-Di19 PF05605.12 KIK56450.1 - 0.019 15.2 6.3 5.6 7.3 3.5 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sina PF03145.16 KIK56450.1 - 0.085 12.8 2.7 0.19 11.6 1.9 1.9 1 1 1 2 2 2 0 Seven in absentia protein family zf-met PF12874.7 KIK56450.1 - 0.1 13.0 0.0 1.9 9.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIK56450.1 - 0.13 12.6 1.2 13 6.2 0.2 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KIK56450.1 - 0.23 11.3 1.0 34 4.3 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-TRAF PF02176.18 KIK56450.1 - 0.24 12.1 4.3 4.2 8.1 1.7 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger OrsD PF12013.8 KIK56450.1 - 0.37 11.2 5.9 53 4.3 0.1 3.2 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D SelB-wing_3 PF09107.11 KIK56451.1 - 0.036 13.7 0.2 0.077 12.6 0.2 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix BaffR-Tall_bind PF09256.10 KIK56451.1 - 0.094 12.5 0.2 0.094 12.5 0.2 2.2 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding Opiods_neuropep PF01160.18 KIK56453.1 - 0.014 15.5 0.5 0.024 14.7 0.5 1.3 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide RecR PF02132.15 KIK56453.1 - 0.083 12.5 0.2 0.15 11.6 0.2 1.5 1 1 0 1 1 1 0 RecR protein zf-C2H2 PF00096.26 KIK56454.1 - 4.1e-06 26.9 9.4 0.013 15.9 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK56454.1 - 6.5e-06 26.6 6.2 0.47 11.4 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK56454.1 - 1.3e-05 24.9 8.2 0.021 14.6 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK56454.1 - 7.8e-05 22.9 11.3 0.00012 22.3 0.1 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-Di19 PF05605.12 KIK56454.1 - 0.043 14.1 7.3 3.6 8.0 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KIK56454.1 - 0.28 11.4 2.8 0.23 11.7 0.9 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 KIK56454.1 - 1.5 8.9 4.3 13 5.9 4.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF4106 PF13388.6 KIK56454.1 - 6.1 6.0 6.7 8.5 5.5 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1664 PF07889.12 KIK56456.1 - 0.011 15.8 0.3 0.015 15.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 KIK56456.1 - 0.5 8.1 3.6 0.63 7.8 3.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Rep_fac-A_3 PF08661.11 KIK56457.1 - 8.2e-07 29.3 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 CDtoxinA PF03498.14 KIK56458.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain DivIC PF04977.15 KIK56459.1 - 0.54 10.1 4.8 0.93 9.3 4.8 1.3 1 0 0 1 1 1 0 Septum formation initiator CxC4 PF18717.1 KIK56460.1 - 1.2e-43 148.1 0.0 1.9e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK56461.1 - 0.0001 22.0 0.2 0.00012 21.7 0.2 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase UPF0564 PF10595.9 KIK56462.1 - 0.0079 15.3 4.8 0.018 14.1 4.8 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 zf-C2H2 PF00096.26 KIK56466.1 - 1.8e-06 28.1 9.4 0.0094 16.4 0.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK56466.1 - 3.2e-06 27.5 6.2 0.34 11.9 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK56466.1 - 5.4e-06 26.0 8.2 0.015 15.1 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK56466.1 - 4.2e-05 23.8 11.6 8.9e-05 22.7 0.1 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-Di19 PF05605.12 KIK56466.1 - 0.02 15.2 7.2 2.6 8.4 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KIK56466.1 - 0.29 11.4 3.3 0.15 12.3 0.9 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF601 PF04642.12 KIK56466.1 - 0.37 10.2 2.1 0.66 9.4 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF601 DZR PF12773.7 KIK56466.1 - 0.84 9.7 4.3 8 6.6 4.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KIK56466.1 - 0.91 9.7 3.7 11 6.3 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain OrsD PF12013.8 KIK56466.1 - 1 9.8 5.7 22 5.6 0.1 3.1 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4106 PF13388.6 KIK56466.1 - 2.5 7.3 5.7 3.6 6.7 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MerC PF03203.14 KIK56467.1 - 0.015 15.7 6.5 0.72 10.3 2.2 2.7 1 1 1 2 2 2 0 MerC mercury resistance protein Oxidored_q2 PF00420.24 KIK56467.1 - 1.7 8.3 7.2 0.52 10.0 3.8 2.0 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L GET2 PF08690.10 KIK56468.1 - 0.16 11.6 2.8 0.21 11.2 2.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Solute_trans_a PF03619.16 KIK56471.1 - 6e-80 268.6 15.4 7.2e-80 268.3 15.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BTB PF00651.31 KIK56472.1 - 0.00052 20.2 0.1 0.0011 19.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Epiglycanin_C PF14654.6 KIK56473.1 - 0.042 13.9 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region BTB PF00651.31 KIK56473.1 - 0.079 13.2 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KIK56474.1 - 0.00023 21.4 0.3 0.00062 20.0 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain MMR_HSR1 PF01926.23 KIK56475.1 - 5.3e-09 36.2 0.0 6.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK56475.1 - 9e-07 28.4 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK56475.1 - 2.3e-05 24.5 0.3 0.0003 20.9 0.4 2.1 2 0 0 2 2 2 1 Dynamin family Roc PF08477.13 KIK56475.1 - 0.00069 19.8 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK56475.1 - 0.00097 19.1 0.1 0.0023 17.8 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIK56475.1 - 0.0022 18.5 0.4 0.0036 17.8 0.3 1.6 1 1 1 2 2 2 1 ABC transporter AAA_16 PF13191.6 KIK56475.1 - 0.011 16.2 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 KIK56475.1 - 0.011 14.9 0.1 0.022 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ras PF00071.22 KIK56475.1 - 0.043 13.4 0.1 0.084 12.5 0.1 1.7 1 1 0 1 1 1 0 Ras family AAA PF00004.29 KIK56475.1 - 0.097 13.1 0.1 0.27 11.7 0.1 1.6 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK56475.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIK56475.1 - 0.19 12.0 0.2 0.36 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK56476.1 - 4.2e-07 30.0 0.0 6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK56476.1 - 8.1e-05 22.0 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK56476.1 - 0.00044 20.5 0.0 0.073 13.3 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KIK56476.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KIK56476.1 - 0.095 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KIK56476.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 KIK56476.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras family FMO-like PF00743.19 KIK56477.1 - 3.7e-21 75.1 0.0 5.7e-16 58.0 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK56477.1 - 3.8e-21 75.6 0.0 1.8e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK56477.1 - 3.1e-15 56.2 0.2 1.1e-10 41.3 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK56477.1 - 1.6e-13 50.5 0.0 1.3e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK56477.1 - 1.2e-07 31.9 1.1 0.0025 17.8 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK56477.1 - 3.6e-06 27.5 0.3 0.048 14.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK56477.1 - 1.8e-05 24.8 0.1 0.19 11.8 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KIK56477.1 - 2.6e-05 24.0 0.2 0.27 10.8 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK56477.1 - 5.3e-05 22.7 0.1 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KIK56477.1 - 0.0003 20.1 0.0 0.062 12.5 0.0 3.0 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.12 KIK56477.1 - 0.00042 19.5 0.6 0.12 11.4 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK56477.1 - 0.00043 20.4 0.0 0.19 11.9 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK56477.1 - 0.00044 19.6 0.3 0.083 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KIK56477.1 - 0.0016 18.7 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 KIK56477.1 - 0.0016 17.2 1.2 0.16 10.7 0.0 3.0 4 0 0 4 4 4 1 HI0933-like protein DUF498 PF04430.14 KIK56477.1 - 0.0026 17.8 0.1 0.13 12.3 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF498/DUF598) FAD_binding_2 PF00890.24 KIK56477.1 - 0.0036 16.4 0.9 0.085 11.9 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KIK56477.1 - 0.0037 16.4 4.3 2.3 7.2 0.0 3.7 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KIK56477.1 - 0.023 15.1 0.0 3 8.3 0.2 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Phage_TAC_13 PF16459.5 KIK56477.1 - 0.036 14.5 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC AlaDh_PNT_C PF01262.21 KIK56477.1 - 0.098 11.9 0.2 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KIK56477.1 - 0.13 11.8 0.3 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KIK56477.1 - 0.19 11.6 0.5 12 5.7 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PBP_like_2 PF12849.7 KIK56478.1 - 4.2e-08 33.2 0.7 5.4e-08 32.9 0.7 1.1 1 0 0 1 1 1 1 PBP superfamily domain Phosphonate-bd PF12974.7 KIK56478.1 - 0.015 14.9 0.0 0.041 13.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 KIK56478.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain BLIP PF07467.11 KIK56478.1 - 0.093 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) p450 PF00067.22 KIK56481.1 - 7.9e-73 245.8 0.0 2.4e-72 244.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF4097 PF13349.6 KIK56483.1 - 0.025 13.9 0.3 0.038 13.3 0.3 1.4 1 0 0 1 1 1 0 Putative adhesin NAD_binding_5 PF07994.12 KIK56484.1 - 0.029 13.7 0.2 0.048 13.0 0.2 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase FUSC PF04632.12 KIK56484.1 - 0.036 12.6 0.7 0.054 12.0 0.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prominin PF05478.11 KIK56484.1 - 0.056 11.4 0.3 0.087 10.8 0.3 1.2 1 0 0 1 1 1 0 Prominin Mid2 PF04478.12 KIK56488.1 - 0.0027 17.5 0.2 0.0054 16.6 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MGC-24 PF05283.11 KIK56488.1 - 0.0062 17.0 2.9 0.013 16.0 2.9 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Prominin PF05478.11 KIK56489.1 - 0.16 9.9 0.1 0.22 9.5 0.1 1.1 1 0 0 1 1 1 0 Prominin PqqD PF05402.12 KIK56489.1 - 0.19 12.1 0.9 0.43 10.9 0.1 1.9 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3682 PF12446.8 KIK56491.1 - 0.089 13.3 0.5 0.15 12.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Oleosin PF01277.17 KIK56492.1 - 0.33 10.7 3.6 0.16 11.7 1.2 1.7 2 0 0 2 2 2 0 Oleosin p450 PF00067.22 KIK56493.1 - 6.3e-49 167.0 0.0 8.1e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIK56494.1 - 2.9e-61 207.4 0.0 3.8e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK56494.1 - 2.7e-28 99.3 0.0 6e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK56495.1 - 9e-67 225.5 0.0 1.2e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK56495.1 - 1.6e-35 122.7 0.0 2.9e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK56495.1 - 3.8e-06 27.0 0.2 0.00018 21.7 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK56495.1 - 6.1e-06 26.0 1.0 8e-05 22.4 1.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK56495.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK56495.1 - 0.00022 20.4 1.0 0.0048 16.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK56495.1 - 0.00023 20.5 0.2 0.0032 16.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK56495.1 - 0.0054 17.3 0.1 1.1 9.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK56495.1 - 0.13 11.6 0.1 5.7 6.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldo_ket_red PF00248.21 KIK56496.1 - 4e-76 256.0 0.0 4.6e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2 PF00096.26 KIK56497.1 - 0.0011 19.3 8.5 0.052 14.0 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK56497.1 - 0.12 13.2 7.3 1.3 10.1 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 KIK56497.1 - 0.13 11.9 1.2 0.49 10.0 1.2 2.0 1 1 0 1 1 1 0 MYST family zinc finger domain p450 PF00067.22 KIK56498.1 - 3.1e-56 191.0 0.0 4e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK56499.1 - 1.8e-57 195.1 0.0 2.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KIK56500.1 - 1.8e-06 27.1 0.0 4.9e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) HTH_53 PF18606.1 KIK56500.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Sterol_MT_C PF08498.10 KIK56503.1 - 7.3e-26 90.3 0.5 1.2e-25 89.6 0.5 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KIK56503.1 - 1.9e-16 60.2 0.0 3.9e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK56503.1 - 4.7e-16 59.2 0.0 8.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK56503.1 - 1.4e-14 54.5 0.0 2.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK56503.1 - 2.3e-12 46.8 0.0 2.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIK56503.1 - 1e-10 41.7 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK56503.1 - 4.4e-10 40.2 0.0 7.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK56503.1 - 5.3e-09 35.8 0.0 8.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK56503.1 - 1e-06 28.7 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KIK56503.1 - 0.00033 19.9 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltr_RsmB-F PF01189.17 KIK56503.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 KIK56503.1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KIK56503.1 - 0.0028 17.3 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 KIK56503.1 - 0.013 16.5 0.0 0.037 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIK56503.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KIK56503.1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KIK56503.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KIK56503.1 - 0.2 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Ribosomal_S17e PF00833.18 KIK56507.1 - 8.4e-57 190.4 0.0 1.1e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 KIK56508.1 - 2.9e-25 88.7 0.1 3.8e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 adh_short_C2 PF13561.6 KIK56510.1 - 3e-47 161.2 0.3 3.8e-47 160.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK56510.1 - 5.3e-34 117.4 0.7 6.5e-34 117.1 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK56510.1 - 6e-10 39.3 0.1 9e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 KIK56510.1 - 0.0058 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.22 KIK56510.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 PA domain HMG_box PF00505.19 KIK56512.1 - 3.6e-19 68.9 1.9 5.6e-19 68.3 1.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK56512.1 - 2.9e-14 53.4 0.7 5e-14 52.6 0.7 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KIK56512.1 - 0.035 14.7 0.0 0.058 13.9 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Pkinase_Tyr PF07714.17 KIK56513.1 - 8.7e-12 44.9 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56513.1 - 6.4e-10 38.8 0.0 9.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Aft1_OSA PF11785.8 KIK56514.1 - 0.0026 18.1 4.3 0.37 11.2 0.1 2.6 2 0 0 2 2 2 2 Aft1 osmotic stress response (OSM) domain Aft1_OSA PF11785.8 KIK56517.1 - 0.067 13.6 3.0 0.16 12.4 0.1 2.5 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain DUF5418 PF17439.2 KIK56518.1 - 0.16 12.0 7.5 0.16 12.1 2.1 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5418) DUF3237 PF11578.8 KIK56521.1 - 0.00028 20.8 0.1 0.00037 20.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Pex24p PF06398.11 KIK56522.1 - 2.9 6.8 4.5 1.5 7.7 0.0 2.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin CENP-B_dimeris PF09026.10 KIK56524.1 - 2.4 8.6 16.8 0.16 12.4 10.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KIK56524.1 - 4.9 6.8 9.1 0.39 10.4 3.9 1.7 1 1 1 2 2 2 0 FAM176 family WD40 PF00400.32 KIK56525.1 - 3.5e-148 477.0 36.5 1.1e-10 41.9 0.1 15.6 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56525.1 - 2e-42 143.4 15.1 0.019 15.2 0.0 14.2 1 1 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56525.1 - 4.5e-31 108.3 6.1 3.1e-05 23.9 0.0 6.6 1 1 5 7 7 7 7 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK56525.1 - 5.3e-14 52.2 10.4 3.7 6.8 0.0 11.6 5 4 7 13 13 13 3 WD40-like domain Nup160 PF11715.8 KIK56525.1 - 3.1e-13 49.2 27.0 0.61 8.7 0.0 12.1 6 4 6 14 14 14 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK56525.1 - 3.7e-11 42.6 9.1 13 4.7 0.0 12.5 3 2 11 15 15 15 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK56525.1 - 2.5e-10 40.0 0.0 42 4.2 0.0 11.5 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK56525.1 - 2.7e-08 33.9 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SdiA-regulated PF06977.11 KIK56525.1 - 1.4e-05 24.5 0.0 2.3 7.4 0.0 5.1 2 2 3 6 6 6 1 SdiA-regulated AAA_16 PF13191.6 KIK56525.1 - 4.2e-05 24.0 0.0 0.00028 21.3 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain DsbC_N PF10411.9 KIK56525.1 - 0.00011 21.6 9.8 74 2.9 0.0 10.1 11 0 0 11 11 11 0 Disulfide bond isomerase protein N-terminus NHL PF01436.21 KIK56525.1 - 0.00074 19.4 18.8 29 4.9 0.0 10.6 12 0 0 12 12 11 0 NHL repeat nos_propeller PF18764.1 KIK56525.1 - 0.0038 17.1 29.0 15 5.5 0.0 11.4 13 2 2 15 15 15 0 Nitrous oxide reductase propeller repeat PLL PF18587.1 KIK56525.1 - 0.016 15.3 0.0 5.5 7.1 0.0 4.6 5 1 2 7 7 7 0 PTX/LNS-Like (PLL) domain APS_kinase PF01583.20 KIK56525.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KIK56525.1 - 0.13 12.8 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.32 KIK56526.1 - 1.9e-113 367.1 44.5 1.4e-11 44.7 0.1 12.4 12 1 1 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56526.1 - 3.1e-28 97.9 10.3 0.022 15.0 0.0 10.4 1 1 10 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56526.1 - 8.8e-18 64.9 6.0 6.5e-06 26.1 0.1 5.6 1 1 5 7 7 7 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK56526.1 - 1.5e-12 46.9 18.1 0.14 10.8 0.0 9.7 6 2 1 10 10 10 5 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK56526.1 - 3.6e-11 43.0 2.6 4.7 6.5 0.0 8.4 9 0 0 9 9 9 3 WD40-like domain Ge1_WD40 PF16529.5 KIK56526.1 - 8e-07 28.3 5.6 9.7 5.0 0.0 7.8 1 1 8 9 9 9 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK56526.1 - 9.8e-07 28.6 5.7 17 5.5 0.0 8.7 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat FlgT_M PF16539.5 KIK56526.1 - 6.7e-05 23.1 3.9 15 5.7 0.0 6.8 4 2 4 8 8 8 0 Flagellar assembly protein T, middle domain NHL PF01436.21 KIK56526.1 - 9.6e-05 22.2 10.1 8.1 6.7 0.0 8.1 9 0 0 9 9 9 1 NHL repeat COPI_C PF06957.11 KIK56526.1 - 0.00011 21.1 0.0 45 2.6 0.0 6.2 2 2 6 8 8 8 0 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KIK56526.1 - 0.00055 19.1 5.3 0.01 14.9 0.6 3.2 1 1 2 3 3 3 2 Coatomer WD associated region MMS1_N PF10433.9 KIK56526.1 - 0.0017 17.1 0.0 2.2 6.8 0.0 3.9 2 1 2 4 4 4 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DsbC_N PF10411.9 KIK56526.1 - 0.003 17.0 4.2 1.1e+02 2.3 0.0 7.6 9 0 0 9 9 9 0 Disulfide bond isomerase protein N-terminus nos_propeller PF18764.1 KIK56526.1 - 0.0075 16.2 26.2 18 5.4 0.0 9.7 11 0 0 11 11 11 0 Nitrous oxide reductase propeller repeat NACHT PF05729.12 KIK56526.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Cuticle_4 PF15955.5 KIK56526.1 - 0.72 10.6 6.5 2.7e+02 2.4 0.0 6.8 10 0 0 10 10 10 0 Cuticle protein DUF2574 PF10836.8 KIK56526.1 - 1.8 8.5 4.5 18 5.3 0.0 4.7 6 2 2 8 8 8 0 Protein of unknown function (DUF2574) WD40 PF00400.32 KIK56530.1 - 4.9e-46 153.8 17.4 3.5e-09 37.1 0.4 7.4 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56530.1 - 3.6e-10 40.0 0.2 0.0033 17.7 0.0 5.1 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56530.1 - 4.1e-07 30.1 0.1 0.0049 16.8 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK56530.1 - 6.5e-07 28.4 2.5 0.033 12.8 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK56530.1 - 6.7e-05 21.8 4.0 0.0048 15.7 0.6 3.4 1 1 1 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 KIK56530.1 - 8.8e-05 21.6 0.4 0.036 13.0 0.1 3.7 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK56530.1 - 0.0044 16.9 0.0 3.2 7.8 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DsbC_N PF10411.9 KIK56530.1 - 0.0054 16.1 0.3 43 3.7 0.0 4.8 5 0 0 5 5 5 0 Disulfide bond isomerase protein N-terminus MMS1_N PF10433.9 KIK56530.1 - 0.019 13.6 0.0 5.7 5.4 0.0 2.8 1 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40_like PF17005.5 KIK56530.1 - 0.037 13.4 0.0 9.2 5.5 0.0 3.7 3 1 2 5 5 5 0 WD40-like domain nos_propeller PF18764.1 KIK56530.1 - 0.043 13.7 3.9 5.1 7.1 0.1 4.0 4 1 1 5 5 5 0 Nitrous oxide reductase propeller repeat NHL PF01436.21 KIK56530.1 - 0.054 13.5 1.1 18 5.6 0.0 3.8 4 0 0 4 4 4 0 NHL repeat Colicin_D PF11429.8 KIK56530.1 - 0.1 13.0 0.1 9.3 6.8 0.0 3.5 3 1 1 4 4 4 0 Colicin D PQQ_3 PF13570.6 KIK56530.1 - 0.5 10.9 16.8 0.2 12.2 0.7 5.4 4 3 2 6 6 6 0 PQQ-like domain Big_4 PF07532.11 KIK56530.1 - 0.94 9.3 15.5 1.5 8.6 0.5 5.2 5 1 0 5 5 5 0 Bacterial Ig-like domain (group 4) Aldedh PF00171.22 KIK56531.1 - 6e-105 351.4 3.1 2.5e-67 227.4 0.1 2.8 1 1 1 2 2 2 2 Aldehyde dehydrogenase family WD40 PF00400.32 KIK56533.1 - 1.3e-100 326.5 24.8 3.8e-11 43.3 0.0 10.2 8 2 2 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56533.1 - 6.4e-34 116.1 2.2 0.012 15.9 0.0 8.5 1 1 8 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56533.1 - 2.9e-22 79.5 0.4 2.4e-07 30.8 0.0 4.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK56533.1 - 1.7e-15 57.1 3.1 1.2 8.4 0.0 8.2 8 1 0 8 8 8 5 WD40-like domain Nup160 PF11715.8 KIK56533.1 - 3.6e-15 55.6 5.0 0.086 11.5 0.0 7.9 4 2 4 8 8 8 6 Nucleoporin Nup120/160 PD40 PF07676.12 KIK56533.1 - 6.2e-12 45.1 0.1 39 4.3 0.0 9.2 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56533.1 - 2.2e-10 40.0 3.3 4.3 6.2 0.0 7.7 3 3 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK56533.1 - 4.3e-09 36.2 15.5 4.4 7.3 0.0 9.5 9 1 0 10 10 10 1 Nitrous oxide reductase propeller repeat NHL PF01436.21 KIK56533.1 - 1.2e-08 34.5 14.1 13 6.1 0.0 9.2 9 0 0 9 9 9 0 NHL repeat potato_inhibit PF00280.18 KIK56533.1 - 1.2e-07 32.3 3.0 60 4.4 0.0 7.7 5 3 3 8 8 8 0 Potato inhibitor I family DsbC_N PF10411.9 KIK56533.1 - 4.6e-07 29.2 7.3 31 4.1 0.0 8.7 9 0 0 9 9 9 0 Disulfide bond isomerase protein N-terminus DUF5122 PF17164.4 KIK56533.1 - 6.9e-07 29.5 5.3 10 6.5 0.0 8.1 9 0 0 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller FlgT_M PF16539.5 KIK56533.1 - 3.6e-06 27.2 5.2 31 4.7 0.0 7.6 4 2 3 8 8 8 0 Flagellar assembly protein T, middle domain Peptidase_S9_N PF02897.15 KIK56533.1 - 1.7e-05 23.8 1.8 5.8 5.6 0.0 6.0 2 1 2 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain COPI_C PF06957.11 KIK56533.1 - 0.00042 19.2 0.0 7.6 5.2 0.0 4.4 3 1 1 5 5 5 1 Coatomer (COPI) alpha subunit C-terminus CHAP PF05257.16 KIK56533.1 - 0.006 17.1 29.4 0.49 11.0 2.5 6.6 3 2 3 6 6 6 3 CHAP domain Imm17 PF15562.6 KIK56533.1 - 0.091 12.6 0.0 77 3.3 0.0 4.7 6 0 0 6 6 6 0 Immunity protein 17 DUF5570 PF17731.1 KIK56533.1 - 0.16 12.1 13.0 0.81 9.8 0.1 5.7 4 3 2 7 7 7 0 Family of unknown function (DUF5570) PQQ_3 PF13570.6 KIK56533.1 - 0.54 10.8 32.2 11 6.7 0.0 8.7 4 3 5 9 9 8 0 PQQ-like domain GCV_T_C PF08669.11 KIK56533.1 - 0.74 9.8 6.1 17 5.4 0.2 4.9 5 0 0 5 5 5 0 Glycine cleavage T-protein C-terminal barrel domain Colicin_E5 PF12106.8 KIK56533.1 - 2.6 8.4 23.4 74 3.7 0.1 8.4 9 1 0 9 9 9 0 Colicin E5 ribonuclease domain Phage_sheath_1 PF04984.14 KIK56533.1 - 5.3 6.9 9.0 2.1e+02 1.6 0.0 6.1 7 1 2 9 9 8 0 Phage tail sheath protein subtilisin-like domain WD40 PF00400.32 KIK56534.1 - 1.4e-08 35.2 0.5 1.4e-08 35.2 0.5 3.4 3 1 0 3 3 3 1 WD domain, G-beta repeat WD40 PF00400.32 KIK56535.1 - 1.3e-92 301.2 13.3 1.2e-12 48.2 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56535.1 - 1.6e-31 108.5 0.9 0.0038 17.5 0.0 7.7 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56535.1 - 4.4e-18 65.9 0.2 2.2e-06 27.7 0.0 4.4 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK56535.1 - 1.7e-12 46.9 0.0 26 4.9 0.0 8.4 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56535.1 - 3.4e-12 46.0 1.2 0.55 9.1 0.0 7.2 1 1 6 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK56535.1 - 2.2e-11 43.5 9.5 2.8 7.9 0.0 8.0 7 1 0 8 8 8 1 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KIK56535.1 - 3.6e-11 42.4 4.4 3.4 6.2 0.0 6.9 4 2 2 7 7 7 5 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK56535.1 - 4.8e-11 42.5 0.8 4.1 6.6 0.0 6.9 7 0 0 7 7 7 1 WD40-like domain potato_inhibit PF00280.18 KIK56535.1 - 1.9e-08 34.8 0.1 23 5.7 0.0 6.9 5 2 2 7 7 7 0 Potato inhibitor I family NHL PF01436.21 KIK56535.1 - 5.7e-06 26.1 13.0 24 5.2 0.1 7.9 8 0 0 8 8 8 0 NHL repeat DsbC_N PF10411.9 KIK56535.1 - 8.3e-06 25.2 6.5 30 4.2 0.0 7.4 8 0 0 8 8 8 0 Disulfide bond isomerase protein N-terminus Cytochrom_D1 PF02239.16 KIK56535.1 - 9.8e-05 21.0 11.9 1 7.8 0.1 4.8 1 1 1 4 4 4 3 Cytochrome D1 heme domain DUF5122 PF17164.4 KIK56535.1 - 0.00071 19.8 10.4 77 3.7 0.0 7.2 8 0 0 8 8 7 0 Domain of unknown function (DUF5122) beta-propeller COPI_C PF06957.11 KIK56535.1 - 0.00072 18.4 0.0 7.6 5.2 0.0 4.4 1 1 2 5 5 5 0 Coatomer (COPI) alpha subunit C-terminus AsnC_trans_reg PF01037.21 KIK56535.1 - 0.00096 19.1 1.2 91 3.1 0.0 6.0 7 0 0 7 7 7 0 Lrp/AsnC ligand binding domain Proteasome_A_N PF10584.9 KIK56535.1 - 0.0014 18.2 8.5 2.6e+02 1.4 0.0 9.4 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KIK56535.1 - 0.0051 17.3 34.0 2.9 8.5 0.4 7.5 2 2 5 7 7 7 3 PQQ-like domain SymE_toxin PF08845.10 KIK56535.1 - 0.12 12.4 14.7 1.2e+02 2.9 0.1 6.5 7 0 0 7 7 6 0 Toxin SymE, type I toxin-antitoxin system Cyclophil_like PF04126.13 KIK56535.1 - 0.14 12.0 2.5 31 4.4 0.0 5.2 7 1 1 8 8 8 0 Cyclophilin-like Cuticle_4 PF15955.5 KIK56535.1 - 0.17 12.6 1.7 5.3e+02 1.4 0.0 5.4 7 0 0 7 7 6 0 Cuticle protein HAD PF12710.7 KIK56535.1 - 0.18 12.2 0.1 55 4.1 0.0 3.7 3 2 2 5 5 5 0 haloacid dehalogenase-like hydrolase Phage_sheath_1 PF04984.14 KIK56535.1 - 0.42 10.5 4.5 2.4e+02 1.5 0.0 5.6 7 0 0 7 7 7 0 Phage tail sheath protein subtilisin-like domain Big_4 PF07532.11 KIK56535.1 - 0.54 10.0 23.3 29 4.5 0.2 7.6 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 4) Colicin_E5 PF12106.8 KIK56535.1 - 0.58 10.5 18.3 1.1e+02 3.3 0.1 7.0 7 1 1 8 8 7 0 Colicin E5 ribonuclease domain CCDC84 PF14968.6 KIK56536.1 - 0.19 11.3 0.5 0.27 10.8 0.5 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 WD40 PF00400.32 KIK56537.1 - 1.6e-118 383.2 41.4 5.7e-11 42.8 0.1 13.5 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56537.1 - 3.6e-38 129.8 6.2 0.0063 16.8 0.0 11.4 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56537.1 - 3.7e-23 82.4 0.1 6.6e-06 26.1 0.0 5.1 1 1 2 5 5 5 5 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK56537.1 - 1.2e-11 44.5 0.9 11 5.2 0.0 9.1 6 3 2 8 8 8 2 WD40-like domain PD40 PF07676.12 KIK56537.1 - 5.6e-10 38.9 1.8 14 5.7 0.0 9.7 11 0 0 11 11 10 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56537.1 - 3.8e-08 32.7 3.7 7.2 5.5 0.0 9.0 2 2 8 11 11 11 1 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK56537.1 - 3.9e-08 33.1 14.9 4.4 7.3 0.0 9.8 10 0 0 10 10 10 1 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 KIK56537.1 - 2.7e-06 26.4 14.2 1.5 7.4 0.0 7.9 2 2 7 9 9 9 3 Nucleoporin Nup120/160 DUF4784 PF16023.5 KIK56537.1 - 3.8e-06 26.1 0.0 3.2 6.6 0.0 5.8 3 2 2 6 6 6 1 Domain of unknown function (DUF4784) NHL PF01436.21 KIK56537.1 - 4.8e-05 23.2 12.2 34 4.7 0.0 9.7 11 0 0 11 11 11 0 NHL repeat NACHT PF05729.12 KIK56537.1 - 0.00045 20.2 1.1 0.017 15.1 0.1 2.3 2 0 0 2 2 2 1 NACHT domain SdiA-regulated PF06977.11 KIK56537.1 - 0.0025 17.1 0.0 4.8 6.3 0.0 4.1 2 1 2 4 4 4 1 SdiA-regulated PLL PF18587.1 KIK56537.1 - 0.0059 16.7 0.0 12 6.0 0.0 3.7 4 0 0 4 4 4 0 PTX/LNS-Like (PLL) domain AAA_16 PF13191.6 KIK56537.1 - 0.026 14.9 0.3 0.67 10.3 0.3 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KIK56537.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_binding_1 PF01035.20 KIK56538.1 - 3.5e-22 78.3 0.1 4.4e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Dimer_Tnp_hAT PF05699.14 KIK56539.1 - 4.3e-06 26.4 0.0 4.5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KIK56540.1 - 0.093 12.8 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 BED zinc finger WD40 PF00400.32 KIK56545.1 - 8.7e-53 175.1 9.3 2e-11 44.3 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56545.1 - 1.2e-16 60.7 0.6 0.018 15.3 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56545.1 - 9.3e-11 42.0 0.0 9.1e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK56545.1 - 2.9e-09 36.1 0.4 0.25 9.9 0.0 4.8 3 1 1 5 5 5 3 Nucleoporin Nup120/160 DsbC_N PF10411.9 KIK56545.1 - 3.9e-07 29.4 0.7 3.7 7.1 0.0 5.2 5 0 0 5 5 5 1 Disulfide bond isomerase protein N-terminus Ge1_WD40 PF16529.5 KIK56545.1 - 9.4e-07 28.1 0.3 0.63 8.9 0.0 4.2 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK56545.1 - 1.2e-06 28.2 0.0 25 5.0 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK56545.1 - 1.9e-06 27.7 4.0 3 7.8 0.1 4.9 5 0 0 5 5 5 3 Nitrous oxide reductase propeller repeat WD40_like PF17005.5 KIK56545.1 - 2.2e-06 27.3 0.0 2 7.7 0.0 4.6 4 1 1 5 5 5 2 WD40-like domain potato_inhibit PF00280.18 KIK56545.1 - 1.6e-05 25.4 0.1 16 6.2 0.0 4.8 2 1 3 5 5 5 0 Potato inhibitor I family DUF5122 PF17164.4 KIK56545.1 - 0.00012 22.2 0.6 28 5.1 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller DUF4875 PF16175.5 KIK56545.1 - 0.0019 18.3 14.9 2.2 8.4 0.2 4.9 1 1 4 5 5 5 2 Domain of unknown function (DUF4875) NHL PF01436.21 KIK56545.1 - 0.0033 17.4 5.7 28 5.0 0.1 5.0 5 0 0 5 5 5 0 NHL repeat Proteasome_A_N PF10584.9 KIK56545.1 - 0.0095 15.6 2.8 47 3.8 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TTR-52 PF01060.23 KIK56545.1 - 0.013 16.2 0.1 11 6.8 0.0 3.4 1 1 2 3 3 3 0 Transthyretin-like family Big_4 PF07532.11 KIK56545.1 - 0.029 14.1 13.1 22 4.9 0.1 5.4 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 4) SymE_toxin PF08845.10 KIK56545.1 - 0.18 11.9 3.5 73 3.5 0.1 3.5 3 0 0 3 3 3 0 Toxin SymE, type I toxin-antitoxin system DUF4596 PF15363.6 KIK56545.1 - 3.2 8.0 5.8 37 4.6 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4596) LPD24 PF18839.1 KIK56545.1 - 8.4 6.7 10.2 3.2 8.1 0.2 4.1 5 0 0 5 5 5 0 Large polyvalent protein associated domain 24 WD40 PF00400.32 KIK56548.1 - 1.1e-101 329.9 36.1 1.8e-10 41.3 0.2 11.7 10 2 1 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56548.1 - 4.6e-31 107.0 5.2 0.0073 16.6 0.0 9.1 1 1 7 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56548.1 - 5.1e-18 65.6 1.5 0.00062 19.7 0.0 5.7 2 2 1 5 5 5 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK56548.1 - 2.4e-14 52.8 0.0 44 4.2 0.0 10.8 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK56548.1 - 1.1e-09 38.1 1.1 4.9 6.4 0.0 8.0 9 0 0 9 9 9 1 WD40-like domain Ge1_WD40 PF16529.5 KIK56548.1 - 5.3e-09 35.5 1.8 5.4 5.9 0.0 7.5 3 2 5 9 9 9 1 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK56548.1 - 5.9e-08 32.5 20.9 12 5.9 0.1 9.7 11 0 0 11 11 10 0 Nitrous oxide reductase propeller repeat NHL PF01436.21 KIK56548.1 - 7.1e-08 32.1 14.2 55 4.1 0.0 10.2 11 0 0 11 11 10 0 NHL repeat DsbC_N PF10411.9 KIK56548.1 - 6.1e-07 28.8 9.2 29 4.2 0.0 9.1 9 0 0 9 9 9 0 Disulfide bond isomerase protein N-terminus Nup160 PF11715.8 KIK56548.1 - 1.3e-06 27.4 11.9 0.6 8.7 0.1 7.0 3 2 4 8 8 8 2 Nucleoporin Nup120/160 CHAP PF05257.16 KIK56548.1 - 3.2e-05 24.4 38.3 1.7 9.3 0.7 8.2 1 1 4 5 5 5 3 CHAP domain DUF5122 PF17164.4 KIK56548.1 - 0.0001 22.5 9.9 58 4.1 0.0 8.4 9 0 0 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller DUF4072 PF13284.6 KIK56548.1 - 0.00085 19.7 0.0 8.8 6.9 0.0 6.4 10 0 0 10 10 7 0 Domain of unknown function (DUF4072) Cuticle_4 PF15955.5 KIK56548.1 - 0.0072 17.0 0.3 58 4.5 0.0 5.7 7 1 1 8 8 6 0 Cuticle protein GCV_T_C PF08669.11 KIK56548.1 - 0.0092 15.9 15.4 23 5.0 0.1 7.8 7 1 0 8 8 8 0 Glycine cleavage T-protein C-terminal barrel domain AsnC_trans_reg PF01037.21 KIK56548.1 - 0.018 15.0 4.1 82 3.3 0.0 6.5 9 0 0 9 9 8 0 Lrp/AsnC ligand binding domain Frtz PF11768.8 KIK56548.1 - 0.035 12.4 0.0 2.5 6.3 0.0 3.5 3 2 0 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz COPI_C PF06957.11 KIK56548.1 - 0.08 11.7 0.0 61 2.2 0.0 4.1 2 2 1 4 4 4 0 Coatomer (COPI) alpha subunit C-terminus AHJR-like PF18743.1 KIK56548.1 - 0.11 12.0 0.0 42 3.7 0.0 3.6 3 2 1 4 4 4 0 REase_AHJR-like Emaravirus_P4 PF16505.5 KIK56548.1 - 0.16 10.9 0.0 60 2.5 0.0 4.6 7 1 1 8 8 8 0 P4 movement protein of Emaravirus, and the 30K superfamily DUF5412 PF17428.2 KIK56548.1 - 5.6 6.8 13.8 9.4 6.1 0.0 7.1 9 2 2 11 11 11 0 Family of unknown function (DUF5412) UNC-93 PF05978.16 KIK56548.1 - 6.8 6.4 8.1 67 3.2 0.0 5.5 8 1 1 9 9 8 0 Ion channel regulatory protein UNC-93 PPP4R2 PF09184.11 KIK56549.1 - 0.038 13.6 14.8 0.07 12.7 14.8 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KIK56549.1 - 0.16 11.3 20.3 0.34 10.2 20.3 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KIK56549.1 - 0.2 9.8 16.8 0.34 9.1 16.8 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIK56549.1 - 1.3 8.3 15.4 3.4 7.0 15.4 1.6 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.12 KIK56549.1 - 8.2 4.6 6.0 13 3.9 6.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HAMP PF00672.25 KIK56550.1 - 2e-41 140.1 18.8 1.1e-07 32.1 0.0 8.7 8 0 0 8 8 8 7 HAMP domain HATPase_c PF02518.26 KIK56550.1 - 3.7e-30 104.7 0.1 9.4e-30 103.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK56550.1 - 1.2e-22 80.1 0.9 5.3e-22 78.1 0.2 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KIK56550.1 - 2.7e-17 62.5 1.6 1.2e-16 60.5 1.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 KIK56550.1 - 0.0039 16.4 3.1 0.015 14.4 0.6 2.7 1 1 2 3 3 3 3 Autophagy protein Apg17 DUF3829 PF12889.7 KIK56550.1 - 0.012 15.1 2.3 12 5.3 0.1 4.4 2 2 2 5 5 5 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 KIK56550.1 - 0.53 10.4 2.5 51 4.0 0.0 4.4 4 0 0 4 4 4 0 Stage III sporulation protein D AcylCoA_dehyd_C PF12186.8 KIK56550.1 - 0.72 10.0 7.9 58 3.9 0.1 6.0 6 1 1 7 7 7 0 Acyl-CoA dehydrogenase C terminal T4SS PF07996.11 KIK56550.1 - 1.8 9.0 7.1 20 5.5 0.1 3.6 3 1 0 4 4 4 0 Type IV secretion system proteins DUF4795 PF16043.5 KIK56550.1 - 2.1 7.9 7.7 17 4.9 0.3 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF4795) bZIP_1 PF00170.21 KIK56551.1 - 0.00013 22.0 0.7 0.00023 21.2 0.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Hepatitis_core PF00906.20 KIK56552.1 - 0.042 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen DUF2236 PF09995.9 KIK56553.1 - 1.5e-10 41.6 0.0 4.4e-10 40.1 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2236 PF09995.9 KIK56554.1 - 5.2e-08 33.4 0.2 1e-07 32.4 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Sugar_tr PF00083.24 KIK56555.1 - 5.2e-48 164.0 11.3 1.6e-47 162.4 11.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK56555.1 - 6.3e-31 107.6 31.6 9.9e-27 93.8 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fasciclin PF02469.22 KIK56556.1 - 1.5e-26 93.1 6.8 2e-21 76.5 1.1 3.3 2 1 0 2 2 2 2 Fasciclin domain DUF1348 PF07080.11 KIK56557.1 - 6.4e-58 194.3 3.4 7.4e-58 194.1 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KIK56557.1 - 8.9e-05 23.1 0.3 0.00012 22.6 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIK56557.1 - 0.0084 16.5 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) HDNR PF15115.6 KIK56557.1 - 0.028 14.7 0.3 0.054 13.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif DNA_binding_1 PF01035.20 KIK56559.1 - 1.2e-25 89.4 0.0 1.5e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain WD40 PF00400.32 KIK56560.1 - 6.3e-138 444.6 41.3 2.1e-11 44.1 0.1 12.5 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56560.1 - 4.1e-42 142.4 8.0 0.0099 16.2 0.0 12.1 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56560.1 - 2.2e-23 83.2 4.9 5.8e-06 26.3 0.1 6.3 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK56560.1 - 2.1e-13 50.0 7.4 0.97 8.3 0.0 10.6 1 1 10 12 12 12 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK56560.1 - 6.6e-13 48.6 1.4 0.81 9.0 0.0 8.7 5 2 5 10 10 10 4 WD40-like domain Nup160 PF11715.8 KIK56560.1 - 1e-09 37.6 22.7 0.86 8.2 0.0 10.6 4 3 8 12 12 12 5 Nucleoporin Nup120/160 NACHT PF05729.12 KIK56560.1 - 6.1e-08 32.8 0.0 9.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain nos_propeller PF18764.1 KIK56560.1 - 3.6e-07 30.0 12.3 22 5.1 0.0 10.1 11 0 0 11 11 11 0 Nitrous oxide reductase propeller repeat DUF4988 PF16378.5 KIK56560.1 - 4.9e-07 29.6 0.2 2.7 7.6 0.1 6.1 2 1 3 6 6 6 1 Domain of unknown function potato_inhibit PF00280.18 KIK56560.1 - 1.7e-06 28.6 5.6 11 6.7 0.0 9.2 8 1 4 12 12 11 0 Potato inhibitor I family PD40 PF07676.12 KIK56560.1 - 1.9e-06 27.6 11.5 10 6.2 0.0 9.2 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK56560.1 - 2.2e-05 24.9 0.0 6.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.6 KIK56560.1 - 0.00091 19.6 34.3 1 9.9 0.1 9.4 5 3 4 9 9 9 3 PQQ-like domain APS_kinase PF01583.20 KIK56560.1 - 0.0013 18.6 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Coatomer_WDAD PF04053.14 KIK56560.1 - 0.0049 16.0 6.3 0.5 9.4 1.0 3.6 1 1 3 5 5 5 1 Coatomer WD associated region AAA_22 PF13401.6 KIK56560.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Imm17 PF15562.6 KIK56560.1 - 0.056 13.3 0.0 2.6e+02 1.6 0.0 5.2 5 0 0 5 5 5 0 Immunity protein 17 COPI_C PF06957.11 KIK56560.1 - 0.066 12.0 0.0 17 4.0 0.0 4.0 3 2 0 5 5 5 0 Coatomer (COPI) alpha subunit C-terminus DsbC_N PF10411.9 KIK56560.1 - 0.081 12.4 9.1 43 3.7 0.1 7.7 11 0 0 11 11 10 0 Disulfide bond isomerase protein N-terminus Viral_helicase1 PF01443.18 KIK56560.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIK56560.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glycos_transf_N PF04413.16 KIK56560.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) AAA_30 PF13604.6 KIK56560.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NHL PF01436.21 KIK56560.1 - 0.22 11.7 13.6 52 4.1 0.0 8.0 11 0 0 11 11 9 0 NHL repeat WD40 PF00400.32 KIK56561.1 - 4.6e-123 397.5 28.3 2.8e-11 43.8 0.0 12.4 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56561.1 - 1.8e-34 117.9 5.7 0.028 14.7 0.0 11.2 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK56561.1 - 3.5e-21 76.0 1.9 7.1e-05 22.8 0.1 5.4 1 1 4 6 6 6 6 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK56561.1 - 1e-12 48.0 2.0 1.5 8.1 0.0 9.3 9 1 1 10 10 10 3 WD40-like domain PD40 PF07676.12 KIK56561.1 - 1.2e-12 47.4 0.0 32 4.6 0.0 10.4 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK56561.1 - 1.4e-11 43.7 8.5 1 7.9 0.0 9.2 6 2 2 10 10 10 3 Nucleoporin Nup120/160 nos_propeller PF18764.1 KIK56561.1 - 4.3e-09 36.2 20.4 31 4.5 0.0 10.8 9 2 2 11 11 11 0 Nitrous oxide reductase propeller repeat Ge1_WD40 PF16529.5 KIK56561.1 - 5.7e-08 32.1 4.7 20 4.0 0.0 9.1 1 1 7 10 10 10 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NHL PF01436.21 KIK56561.1 - 1.1e-07 31.5 11.8 6.7 6.9 0.0 10.2 11 0 0 11 11 11 1 NHL repeat DsbC_N PF10411.9 KIK56561.1 - 0.00011 21.6 11.0 1.7e+02 1.8 0.0 9.7 11 0 0 11 11 11 0 Disulfide bond isomerase protein N-terminus COPI_C PF06957.11 KIK56561.1 - 0.00014 20.7 0.0 12 4.5 0.0 5.8 3 2 2 7 7 7 2 Coatomer (COPI) alpha subunit C-terminus FlgT_M PF16539.5 KIK56561.1 - 0.38 10.9 9.5 96 3.1 0.0 7.3 7 2 2 10 10 10 0 Flagellar assembly protein T, middle domain TonB_2 PF13103.6 KIK56562.1 - 0.09 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 TonB C terminal Aldedh PF00171.22 KIK56563.1 - 7.2e-166 552.3 1.4 8.2e-166 552.1 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK56563.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RNA_pol_inhib PF16857.5 KIK56563.1 - 0.33 10.8 1.7 2.8 7.8 0.4 2.9 3 0 0 3 3 3 0 RNA polymerase inhibitor zf-C3HC4_3 PF13920.6 KIK56569.1 - 5.7e-07 29.3 22.5 7.7e-06 25.7 9.8 2.5 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK56569.1 - 1.2e-05 25.2 25.6 1.8e-05 24.6 6.9 3.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK56569.1 - 6.2e-05 23.3 24.5 0.00024 21.4 12.4 2.7 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KIK56569.1 - 7.7e-05 22.5 13.6 7.7e-05 22.5 13.6 3.0 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 KIK56569.1 - 0.0002 21.9 22.9 0.031 15.1 0.9 4.9 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK56569.1 - 0.00034 20.9 21.1 0.023 15.2 2.3 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK56569.1 - 0.0004 20.6 24.0 0.0011 19.2 1.7 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C3HC4 PF00097.25 KIK56569.1 - 0.00048 20.0 12.9 0.00048 20.0 12.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KIK56569.1 - 0.00073 19.6 14.3 0.002 18.2 4.2 3.1 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.6 KIK56569.1 - 0.006 16.6 5.7 0.006 16.6 5.7 3.5 2 2 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK56569.1 - 0.018 15.2 3.8 0.018 15.2 3.8 4.0 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK56569.1 - 0.021 14.7 3.9 0.055 13.3 3.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIK56569.1 - 0.054 13.4 25.0 0.078 12.9 12.1 3.9 2 2 2 4 4 4 0 Prokaryotic RING finger family 4 Vpu PF00558.19 KIK56569.1 - 0.46 10.3 1.4 19 5.1 1.2 2.3 2 0 0 2 2 2 0 Vpu protein zf_C2H2_ZHX PF18387.1 KIK56569.1 - 0.77 9.4 5.2 0.2 11.3 0.8 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 KIK56569.1 - 1.6 8.7 10.4 1 9.4 0.8 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Rtf2 PF04641.12 KIK56569.1 - 2 7.7 7.3 0.1 11.9 1.2 1.9 2 1 0 2 2 2 0 Rtf2 RING-finger zf-rbx1 PF12678.7 KIK56569.1 - 4.8 7.6 22.6 0.052 13.8 11.7 3.0 2 2 1 3 3 2 0 RING-H2 zinc finger domain Elf1 PF05129.13 KIK56569.1 - 5.2 7.2 12.8 22 5.2 7.8 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-DBF PF07535.12 KIK56569.1 - 6.9 6.9 12.4 1.2 9.3 1.5 3.6 3 1 1 4 4 4 0 DBF zinc finger Nop14 PF04147.12 KIK56569.1 - 7.5 4.6 17.7 9.6 4.3 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3602 PF12223.8 KIK56570.1 - 3.9e-08 33.8 7.9 0.00095 19.7 2.8 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) F-box-like PF12937.7 KIK56572.1 - 0.00019 21.3 0.4 0.00047 20.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK56573.1 - 8e-09 35.3 0.1 1.5e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK56573.1 - 0.063 13.2 0.6 0.77 9.7 0.6 2.3 1 1 0 1 1 1 0 F-box domain GATA PF00320.27 KIK56574.1 - 1.4e-07 31.0 7.6 2.4e-07 30.2 7.6 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-MYND PF01753.18 KIK56575.1 - 3.2e-10 39.9 11.1 5.2e-10 39.3 11.1 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK56575.1 - 0.091 13.1 9.1 0.17 12.2 9.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding GATA PF00320.27 KIK56578.1 - 3.4e-07 29.8 6.7 5.9e-07 29.0 6.7 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-MYND PF01753.18 KIK56579.1 - 0.0017 18.4 0.4 0.0028 17.7 0.4 1.3 1 0 0 1 1 1 1 MYND finger TLV_coat PF00429.19 KIK56580.1 - 0.093 11.4 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Pkinase_fungal PF17667.1 KIK56581.1 - 1.3e-45 156.0 1.1 1.4e-45 155.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KIK56581.1 - 0.0069 15.7 0.0 0.019 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK56581.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ish1 PF10281.9 KIK56582.1 - 4.1e-44 148.6 29.7 1.5e-10 41.2 1.2 7.4 8 1 0 8 8 8 6 Putative stress-responsive nuclear envelope protein TnsD PF15978.5 KIK56582.1 - 0.0012 17.9 0.5 0.032 13.2 0.0 2.6 1 1 2 3 3 3 2 Tn7-like transposition protein D BCOR PF15808.5 KIK56582.1 - 1.9 8.7 8.6 0.63 10.2 1.8 2.8 2 1 0 2 2 2 0 BCL-6 co-repressor, non-ankyrin-repeat region GATA PF00320.27 KIK56584.1 - 9.5e-06 25.1 7.3 1.6e-05 24.4 7.3 1.4 1 0 0 1 1 1 1 GATA zinc finger SMN PF06003.12 KIK56584.1 - 1.6 7.9 10.2 0.032 13.5 0.5 2.5 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) Pex14_N PF04695.13 KIK56584.1 - 4.2 8.0 15.0 0.68 10.6 2.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-MYND PF01753.18 KIK56585.1 - 1.6e-10 40.9 12.4 2.4e-10 40.3 12.4 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK56585.1 - 0.057 13.7 10.7 0.12 12.8 10.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HypA PF01155.19 KIK56585.1 - 1 9.4 6.3 1.6 8.8 6.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sdh5 PF03937.16 KIK56588.1 - 1.7e-26 92.0 0.9 2.4e-26 91.5 0.9 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Alginate_lyase2 PF08787.11 KIK56589.1 - 2.3e-33 116.0 0.0 2.6e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase CRCB PF02537.15 KIK56589.1 - 0.015 15.6 0.3 0.026 14.8 0.3 1.5 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) HPS3_N PF14761.6 KIK56589.1 - 0.071 12.6 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Alginate_lyase2 PF08787.11 KIK56590.1 - 2.6e-45 155.1 0.0 3e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 KIK56590.1 - 0.00052 19.9 0.0 0.0087 15.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide lyase Inhibitor_I29 PF08246.12 KIK56592.1 - 0.041 14.3 0.4 0.099 13.1 0.4 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) VWA_N PF08399.11 KIK56592.1 - 0.34 11.4 2.1 0.57 10.7 0.1 2.1 2 0 0 2 2 2 0 VWA N-terminal Alginate_lyase2 PF08787.11 KIK56593.1 - 1.1e-43 149.8 0.0 1.3e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 KIK56593.1 - 0.0032 17.4 0.0 0.092 12.6 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide lyase CRCB PF02537.15 KIK56593.1 - 0.082 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Filamin PF00630.19 KIK56594.1 - 0.13 13.1 0.0 0.25 12.2 0.0 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat Rrn6 PF10214.9 KIK56595.1 - 3.4 6.1 9.5 4.3 5.7 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Menin PF05053.13 KIK56595.1 - 3.8 5.8 4.9 4.1 5.6 4.9 1.2 1 0 0 1 1 1 0 Menin ATP-synt_10 PF05176.14 KIK56596.1 - 7.9e-52 176.0 0.0 1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein FAM75 PF14650.6 KIK56596.1 - 0.9 9.0 8.6 0.09 12.3 3.7 1.7 2 0 0 2 2 2 0 FAM75 family Histone PF00125.24 KIK56597.1 - 7e-18 65.3 0.0 8.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK56597.1 - 6.6e-17 61.0 0.4 1.3e-16 60.0 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK56597.1 - 1.3e-06 28.5 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myb_DNA-bind_5 PF13873.6 KIK56598.1 - 0.39 10.8 2.5 0.29 11.3 0.7 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KIK56599.1 - 0.046 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 KIK56600.1 - 1.9e-07 30.9 0.4 2.9e-07 30.2 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KIK56600.1 - 0.00058 19.8 1.5 0.0013 18.7 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIK56600.1 - 0.058 13.1 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 KIK56601.1 - 5.7e-05 23.3 0.1 8.4e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 KIK56602.1 - 3.5e-05 23.6 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK56602.1 - 9.5e-05 23.0 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK56602.1 - 0.00068 20.1 0.0 0.00082 19.9 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TPR_10 PF13374.6 KIK56603.1 - 3e-77 252.6 6.3 2e-10 40.2 0.0 7.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56603.1 - 3.6e-71 235.5 19.0 8e-15 54.9 0.0 5.7 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56603.1 - 1.4e-20 72.1 4.2 0.071 13.5 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56603.1 - 3.3e-18 66.2 6.9 1e-11 44.8 1.3 3.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KIK56603.1 - 1.1e-16 59.5 9.2 0.0065 16.4 0.1 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56603.1 - 7.1e-15 53.9 13.0 0.049 13.7 0.3 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56603.1 - 3.3e-14 52.0 15.3 0.065 13.1 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK56603.1 - 2e-13 49.4 20.0 0.15 12.4 0.1 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56603.1 - 3.1e-10 39.7 0.0 1.7 9.5 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56603.1 - 1.3e-09 38.4 6.8 4.4 7.9 0.2 6.6 1 1 6 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.9 KIK56603.1 - 5.2e-09 36.0 5.2 0.38 10.5 0.1 4.6 1 1 3 4 4 4 3 26S proteasome subunit RPN7 TPR_16 PF13432.6 KIK56603.1 - 0.00017 22.2 0.0 24 5.7 0.0 5.2 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK56603.1 - 0.00021 21.8 3.1 5.2 8.1 0.1 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF1897 PF09005.10 KIK56603.1 - 0.0027 17.2 11.4 28 4.3 0.0 6.6 7 0 0 7 7 7 0 Domain of unknown function (DUF1897) PPR PF01535.20 KIK56603.1 - 0.023 14.9 12.2 19 5.8 0.0 6.2 7 0 0 7 7 7 0 PPR repeat MORN_2 PF07661.13 KIK56603.1 - 0.024 14.8 0.1 21 5.8 0.0 4.6 5 0 0 5 5 3 0 MORN repeat variant TPR_11 PF13414.6 KIK56603.1 - 0.043 13.5 6.3 33 4.3 0.0 5.9 7 0 0 7 7 7 0 TPR repeat DUF2236 PF09995.9 KIK56603.1 - 0.086 13.0 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) Cytochrom_B562 PF07361.11 KIK56603.1 - 0.09 13.4 6.4 77 4.0 0.0 5.5 7 0 0 7 7 7 0 Cytochrome b562 TPR_3 PF07720.12 KIK56603.1 - 0.34 11.0 8.4 90 3.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK56603.1 - 0.34 11.6 1.5 11 6.9 0.2 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat PPR_1 PF12854.7 KIK56603.1 - 0.54 10.0 12.4 4.9 6.9 0.1 5.9 7 0 0 7 7 7 0 PPR repeat PepSY_TM_like_2 PF16357.5 KIK56605.1 - 0.032 14.2 0.1 0.032 14.2 0.1 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like TauD PF02668.16 KIK56607.1 - 2.2e-60 204.7 0.6 2.7e-60 204.5 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LRR_4 PF12799.7 KIK56608.1 - 0.037 14.5 5.1 5 7.7 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 KIK56610.1 - 6.2e-43 147.1 37.0 6.2e-43 147.1 37.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK56610.1 - 2.9e-05 23.1 1.3 2.9e-05 23.1 1.3 3.4 3 3 3 6 6 6 2 Sugar (and other) transporter MFS_3 PF05977.13 KIK56610.1 - 0.015 13.8 3.0 0.023 13.1 3.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DUF485 PF04341.12 KIK56610.1 - 3.3 7.7 11.4 1 9.4 6.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF563 PF04577.14 KIK56611.1 - 0.0024 18.1 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Abhydrolase_1 PF00561.20 KIK56613.1 - 9.9e-10 38.5 0.0 2.6e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK56613.1 - 8e-07 28.6 0.0 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Hist_deacetyl PF00850.19 KIK56614.1 - 1.2e-59 202.3 0.0 1.5e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Hira PF07569.11 KIK56615.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split TPR_10 PF13374.6 KIK56616.1 - 5.6e-179 576.0 16.4 1.8e-13 49.8 0.0 14.7 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56616.1 - 5.8e-152 494.3 54.6 1.1e-18 67.3 0.1 12.8 1 1 13 14 14 14 14 Tetratricopeptide repeat TPR_8 PF13181.6 KIK56616.1 - 1.1e-37 125.0 44.9 0.0053 16.9 0.2 13.5 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56616.1 - 6.1e-34 113.6 31.0 0.00062 19.6 0.1 13.3 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56616.1 - 4.4e-29 99.1 38.7 0.00089 19.0 0.4 13.1 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56616.1 - 4.1e-28 95.2 37.6 0.01 15.9 0.1 13.0 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56616.1 - 5.5e-25 85.9 22.5 0.067 13.6 0.0 12.7 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56616.1 - 7.3e-17 61.7 15.0 1.5e-09 37.7 5.7 4.8 1 1 2 4 4 4 4 MalT-like TPR region TPR_16 PF13432.6 KIK56616.1 - 1e-11 45.2 6.8 2.8 8.7 0.0 9.4 7 4 3 11 11 10 1 Tetratricopeptide repeat DUF4919 PF16266.5 KIK56616.1 - 7.1e-11 42.4 17.3 0.11 12.5 0.2 7.3 1 1 8 9 9 9 4 Domain of unknown function (DUF4919) TPR_9 PF13371.6 KIK56616.1 - 9.2e-09 35.3 0.0 1.3 9.2 0.0 6.3 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56616.1 - 1.7e-07 31.6 24.9 3.6 8.2 0.3 9.9 2 2 11 13 13 13 3 Tetratricopeptide repeat TPR_3 PF07720.12 KIK56616.1 - 2e-07 30.8 33.6 0.07 13.1 0.2 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56616.1 - 2.2e-07 30.8 0.0 21 6.1 0.0 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Fibritin_C PF07921.12 KIK56616.1 - 0.00012 22.1 0.0 1.2e+02 2.9 0.0 7.8 11 1 0 12 12 9 0 Fibritin C-terminal region kleA_kleC PF17383.2 KIK56616.1 - 0.00048 20.4 20.3 3.5 8.0 0.0 9.0 12 1 1 13 13 9 1 Uncharacterized KorC regulated protein A ANAPC3 PF12895.7 KIK56616.1 - 0.00073 19.7 31.4 1 9.6 1.5 9.1 1 1 6 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 CAML PF14963.6 KIK56616.1 - 0.0021 18.2 1.0 0.16 12.1 0.0 3.7 3 1 2 5 5 4 1 Calcium signal-modulating cyclophilin ligand DUF493 PF04359.14 KIK56616.1 - 0.0083 16.7 0.1 1.1e+02 3.5 0.0 6.0 4 3 1 6 6 5 0 Protein of unknown function (DUF493) Peptidase_S28 PF05577.12 KIK56616.1 - 0.018 13.9 0.9 5.2 5.7 0.0 4.6 4 3 1 6 6 6 0 Serine carboxypeptidase S28 Na_H_antiport_2 PF13726.6 KIK56616.1 - 0.023 14.8 0.2 32 4.8 0.1 5.2 6 1 1 7 7 5 0 Na+-H+ antiporter family AAA_19 PF13245.6 KIK56616.1 - 0.083 13.2 4.2 9.6 6.5 0.7 3.6 1 1 0 2 2 2 0 AAA domain DUF2420 PF10336.9 KIK56616.1 - 0.11 12.5 10.0 20 5.3 0.1 5.7 5 2 1 6 6 6 0 Protein of unknown function (DUF2420) FUSC PF04632.12 KIK56616.1 - 0.13 10.7 1.9 8.8 4.7 0.3 3.3 2 1 0 3 3 3 0 Fusaric acid resistance protein family Fis1_TPR_C PF14853.6 KIK56616.1 - 0.15 12.2 23.2 1.7 8.8 0.2 8.4 10 0 0 10 10 9 0 Fis1 C-terminal tetratricopeptide repeat Gag_p30 PF02093.16 KIK56616.1 - 0.2 11.2 3.1 3.6 7.1 0.1 4.1 2 2 4 6 6 6 0 Gag P30 core shell protein PPR PF01535.20 KIK56616.1 - 0.32 11.3 8.4 66 4.1 0.0 7.2 9 0 0 9 9 7 0 PPR repeat DUF2298 PF10060.9 KIK56616.1 - 0.38 9.4 9.0 3 6.4 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized membrane protein (DUF2298) TPR_11 PF13414.6 KIK56616.1 - 0.57 9.9 17.4 38 4.1 0.0 8.1 9 0 0 9 9 8 0 TPR repeat Death PF00531.22 KIK56616.1 - 3.4 7.9 5.8 32 4.8 0.1 5.1 7 2 0 7 7 6 0 Death domain TPR_6 PF13174.6 KIK56616.1 - 7.3 7.5 16.5 1.1e+02 3.7 0.1 7.8 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF2680 PF10925.8 KIK56616.1 - 9.7 6.3 34.6 22 5.2 0.1 10.2 12 0 0 12 12 12 0 Protein of unknown function (DUF2680) AAA_16 PF13191.6 KIK56617.1 - 0.026 14.9 0.0 0.06 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NADH_u_ox_C PF12853.7 KIK56617.1 - 0.079 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Herpes_UL3 PF03369.13 KIK56618.1 - 0.13 12.8 1.2 0.26 11.8 1.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL3 protein PPP4R2 PF09184.11 KIK56618.1 - 0.33 10.5 2.7 0.55 9.8 2.7 1.5 1 1 0 1 1 1 0 PPP4R2 TPR_10 PF13374.6 KIK56621.1 - 3.5e-73 239.7 4.9 3.9e-12 45.6 0.0 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56621.1 - 5.3e-63 209.3 20.1 8.5e-12 45.2 0.1 6.9 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56621.1 - 2e-15 55.6 4.3 0.013 15.4 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56621.1 - 2.2e-11 43.0 16.4 0.072 12.9 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56621.1 - 2.7e-11 43.4 0.6 3.9e-08 33.0 0.1 2.8 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KIK56621.1 - 8.5e-10 38.1 13.0 1.2 9.5 0.2 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56621.1 - 3.1e-09 37.2 11.1 0.0076 16.7 0.2 6.2 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56621.1 - 1.6e-08 34.0 19.0 0.066 13.4 0.1 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56621.1 - 3.3e-07 30.3 1.7 3.7 8.5 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56621.1 - 6.7e-07 29.3 7.8 4.4 7.9 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK56621.1 - 2e-05 25.1 14.5 0.065 13.9 0.1 6.4 5 3 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK56621.1 - 0.0021 18.7 14.2 0.93 10.5 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK56621.1 - 0.0061 16.7 2.9 2 8.7 0.0 3.2 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Osmo_CC PF08946.10 KIK56621.1 - 0.11 12.8 4.2 14 6.0 0.2 3.9 4 0 0 4 4 3 0 Osmosensory transporter coiled coil DUF1897 PF09005.10 KIK56621.1 - 0.22 11.1 0.2 20 4.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) PPR PF01535.20 KIK56621.1 - 0.23 11.8 0.4 3 8.3 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_11 PF13414.6 KIK56621.1 - 3 7.6 7.8 45 3.8 0.1 4.7 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 KIK56621.1 - 5.8 7.8 12.8 2.4e+02 2.7 0.2 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat BLOC1S3 PF15753.5 KIK56624.1 - 0.094 12.8 3.2 0.098 12.8 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 TPR_10 PF13374.6 KIK56625.1 - 1.9e-118 383.6 12.2 5.7e-12 45.1 0.2 10.0 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56625.1 - 2e-81 268.3 16.7 1.8e-11 44.1 0.1 9.0 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56625.1 - 9.2e-18 64.7 3.2 2e-05 24.2 0.1 4.4 1 1 3 4 4 4 4 MalT-like TPR region TPR_17 PF13431.6 KIK56625.1 - 1.5e-17 62.6 22.6 0.23 11.9 0.1 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56625.1 - 3.6e-17 61.0 19.4 0.039 14.0 0.1 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK56625.1 - 3.1e-13 48.8 20.3 0.19 12.0 0.1 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56625.1 - 2.4e-11 44.0 18.7 3.2 8.3 0.1 8.9 3 3 6 9 9 9 4 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56625.1 - 1.8e-10 40.4 2.3 1.1 10.0 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56625.1 - 8.8e-10 38.0 23.1 1.6 8.7 0.1 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56625.1 - 1.7e-07 30.8 19.6 13 6.2 0.1 9.3 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK56625.1 - 3.1e-07 30.9 9.9 7.2 7.3 0.1 8.2 3 2 6 9 9 9 1 Tetratricopeptide repeat Mrpl_C PF18502.1 KIK56625.1 - 3.6e-05 24.0 3.6 23 5.3 0.0 6.7 1 1 4 7 7 7 0 54S ribosomal protein L8 C-terminal domain DUF3531 PF12049.8 KIK56625.1 - 0.00015 21.7 0.5 60 3.5 0.0 6.7 7 1 0 8 8 8 0 Protein of unknown function (DUF3531) Uteroglobin PF01099.17 KIK56625.1 - 0.0012 19.1 2.2 24 5.3 0.0 5.5 2 1 4 7 7 7 0 Uteroglobin family Phosphatase PF15698.5 KIK56625.1 - 0.0024 17.1 0.9 13 4.9 0.0 5.1 1 1 3 5 5 5 0 Phosphatase DUF493 PF04359.14 KIK56625.1 - 0.022 15.3 0.0 6 7.5 0.0 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF493) DUF2680 PF10925.8 KIK56625.1 - 0.071 13.1 6.0 71 3.5 0.1 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2680) FUSC PF04632.12 KIK56625.1 - 0.21 10.1 0.7 7 5.1 0.0 2.2 1 1 0 2 2 2 0 Fusaric acid resistance protein family LRR_9 PF14580.6 KIK56625.1 - 0.28 10.7 7.3 16 4.9 0.1 4.8 3 2 2 5 5 5 0 Leucine-rich repeat PsaN PF05479.11 KIK56625.1 - 0.72 10.0 4.7 58 3.9 0.1 4.1 2 2 0 3 3 3 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) TPR_14 PF13428.6 KIK56625.1 - 2.1 9.4 14.3 16 6.6 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat SPT6_acidic PF14632.6 KIK56626.1 - 0.006 17.1 1.3 0.0092 16.5 1.3 1.3 1 0 0 1 1 1 1 Acidic N-terminal SPT6 Sacchrp_dh_C PF16653.5 KIK56627.1 - 0.008 16.3 0.0 0.013 15.7 0.0 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain TPR_10 PF13374.6 KIK56628.1 - 2.8e-233 748.7 34.8 1.1e-12 47.4 0.0 19.0 19 0 0 19 19 19 19 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56628.1 - 1.9e-151 492.7 49.6 1.2e-11 44.7 0.5 19.0 1 1 18 19 19 19 18 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56628.1 - 3.3e-38 131.9 14.3 2.3e-09 37.1 0.2 7.0 1 1 5 6 6 6 6 MalT-like TPR region TPR_7 PF13176.6 KIK56628.1 - 4.6e-37 123.3 46.0 0.085 12.9 0.0 18.7 19 0 0 19 19 19 13 Tetratricopeptide repeat TPR_8 PF13181.6 KIK56628.1 - 1.8e-31 105.7 43.8 1.2 9.5 0.1 19.0 19 0 0 19 19 19 9 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56628.1 - 1e-24 86.8 40.2 2.9 8.5 0.1 17.6 2 2 17 19 19 19 8 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56628.1 - 2.2e-21 74.2 21.0 1.2 10.0 0.0 15.6 18 0 0 18 18 17 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56628.1 - 3.4e-21 74.0 46.4 3 8.4 0.0 17.5 18 0 0 18 18 18 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56628.1 - 5e-17 60.9 51.5 1.9 8.5 0.1 18.1 19 0 0 19 19 19 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK56628.1 - 1.9e-15 57.2 15.7 5.9 7.6 0.1 14.9 9 6 6 15 15 15 2 Tetratricopeptide repeat NIR_SIR_ferr PF03460.17 KIK56628.1 - 2.7e-12 46.3 4.3 20 5.1 0.0 14.4 16 2 2 18 18 18 0 Nitrite/Sulfite reductase ferredoxin-like half domain Cytochrom_B562 PF07361.11 KIK56628.1 - 1.6e-11 44.8 17.1 19 6.0 0.0 14.0 14 2 0 15 15 15 0 Cytochrome b562 TPR_2 PF07719.17 KIK56628.1 - 5.1e-09 35.6 41.4 6.2 7.2 0.1 16.7 19 0 0 19 19 19 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK56628.1 - 1.7e-07 31.5 32.7 3.8 8.6 0.1 13.7 13 3 3 16 16 14 1 Tetratricopeptide repeat Uteroglobin PF01099.17 KIK56628.1 - 1.9e-07 31.3 14.3 22 5.4 0.0 11.9 3 3 11 15 15 15 0 Uteroglobin family TPR_3 PF07720.12 KIK56628.1 - 5.5e-05 23.1 36.2 13 5.9 0.0 12.9 13 0 0 13 13 13 0 Tetratricopeptide repeat AAA_19 PF13245.6 KIK56628.1 - 0.28 11.5 17.9 1.1e+02 3.1 2.1 7.9 1 1 0 3 3 3 0 AAA domain HD_6 PF18019.1 KIK56628.1 - 1.9 8.6 8.2 1.2e+02 2.7 0.4 6.2 5 2 2 7 7 7 0 HD domain BLOC1S3 PF15753.5 KIK56630.1 - 0.018 15.2 0.4 0.018 15.2 0.4 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ELYS PF13934.6 KIK56631.1 - 9.1e-37 127.2 0.5 1e-36 127.0 0.5 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly Sec62 PF03839.16 KIK56632.1 - 6.5e-56 189.3 3.5 1.8e-55 187.8 3.5 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 KIK56632.1 - 5.1 6.2 9.3 8 5.6 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Pkinase PF00069.25 KIK56633.1 - 1.1e-08 34.8 0.0 1.2e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK56633.1 - 0.0019 17.6 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2312 PF10073.9 KIK56634.1 - 0.027 14.1 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Pkinase PF00069.25 KIK56635.1 - 2.9e-12 46.5 0.0 3.4e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK56635.1 - 2.4e-05 23.7 0.0 2.7e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3973 PF13119.6 KIK56635.1 - 0.089 12.9 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) DUF812 PF05667.11 KIK56638.1 - 0.049 12.5 0.3 0.074 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SKA1 PF07160.12 KIK56638.1 - 1.7 8.4 4.9 0.64 9.8 0.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pkinase PF00069.25 KIK56639.1 - 4.1e-05 23.1 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK56639.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK56639.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK56639.1 - 0.065 13.1 0.2 11 5.8 0.4 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK56639.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase WaaY PF06176.11 KIK56639.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KIK56639.1 - 0.17 11.4 0.0 1.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase NTF2 PF02136.20 KIK56640.1 - 3.9e-29 101.7 0.1 5.7e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KIK56640.1 - 3.3e-07 30.0 0.0 6.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KIK56641.1 - 1.2e-09 37.9 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK56641.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif F-box-like PF12937.7 KIK56643.1 - 1.4e-08 34.5 1.0 4.5e-08 32.9 1.0 2.0 1 0 0 1 1 1 1 F-box-like Cep57_CLD_2 PF14197.6 KIK56643.1 - 0.01 15.9 0.7 0.021 14.9 0.7 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 LRR_4 PF12799.7 KIK56643.1 - 0.62 10.6 4.3 3.1 8.4 0.8 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Oxidored_FMN PF00724.20 KIK56644.1 - 1.6e-94 317.0 0.0 1.9e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIK56644.1 - 0.053 13.0 0.1 3.7 6.9 0.0 2.9 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel KDZ PF18758.1 KIK56647.1 - 1.2e-49 169.0 0.0 2e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK56647.1 - 5.8e-33 113.3 0.3 1.3e-32 112.1 0.3 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK56647.1 - 4e-07 30.1 0.5 1.3e-06 28.4 0.5 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Spore_Cse60 PF10957.8 KIK56649.1 - 0.17 11.9 0.5 0.67 10.0 0.2 1.9 2 0 0 2 2 2 0 Sporulation protein Cse60 Chromo PF00385.24 KIK56649.1 - 0.22 11.5 0.6 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain 2OG-FeII_Oxy_3 PF13640.6 KIK56650.1 - 2.3e-05 25.2 0.0 4.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cauli_VI PF01693.16 KIK56651.1 - 8.4e-11 42.0 0.2 1.3e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-RING_5 PF14634.6 KIK56651.1 - 0.00077 19.4 0.4 0.0011 18.8 0.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Atrophin-1 PF03154.15 KIK56652.1 - 0.52 8.5 3.9 0.59 8.3 3.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family CAP_N PF01213.19 KIK56655.1 - 0.6 9.5 3.4 0.3 10.5 1.5 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1179 PF06678.11 KIK56655.1 - 3.5 7.6 5.2 0.93 9.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) TPR_10 PF13374.6 KIK56659.1 - 1.1e-110 359.0 10.5 5.5e-12 45.2 0.0 12.0 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56659.1 - 5.3e-93 305.4 37.9 1.9e-13 50.5 0.1 9.1 1 1 8 10 10 10 10 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56659.1 - 2.6e-27 96.1 18.0 1.9e-09 37.4 3.1 3.7 1 1 3 4 4 4 4 MalT-like TPR region TPR_8 PF13181.6 KIK56659.1 - 2.6e-18 64.6 26.0 0.77 10.1 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56659.1 - 2.5e-15 55.6 30.5 0.36 10.7 0.1 11.9 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56659.1 - 2.1e-14 52.4 15.6 0.43 10.7 0.0 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56659.1 - 1.6e-11 43.4 30.2 1.6 9.1 0.0 11.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56659.1 - 2e-10 41.0 20.1 0.98 10.0 0.0 9.5 4 2 5 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56659.1 - 7.7e-09 35.3 25.3 5.1 7.7 0.0 10.3 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK56659.1 - 1.1e-06 29.2 19.2 0.7 10.6 0.0 8.6 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56659.1 - 1.1e-06 28.7 12.0 22 6.0 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK56659.1 - 7.4e-05 22.8 0.4 0.16 12.1 0.0 3.4 3 2 0 3 3 3 2 Tetratricopeptide repeat HTH_34 PF13601.6 KIK56659.1 - 0.0035 17.5 1.2 2.4 8.4 0.0 4.4 4 1 0 4 4 4 1 Winged helix DNA-binding domain MCPVI PF02993.14 KIK56659.1 - 0.02 14.7 0.8 32 4.3 0.0 4.4 2 1 2 5 5 5 0 Minor capsid protein VI baeRF_family11 PF18855.1 KIK56659.1 - 0.081 13.2 0.0 3.4 8.0 0.0 2.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 Agenet PF05641.12 KIK56659.1 - 0.22 12.0 0.0 0.55 10.7 0.0 1.7 1 0 0 1 1 1 0 Agenet domain TPR_14 PF13428.6 KIK56659.1 - 0.3 12.0 22.2 5.5 8.1 0.1 8.5 9 1 0 9 9 9 0 Tetratricopeptide repeat DUF3504 PF12012.8 KIK56659.1 - 0.39 10.6 1.9 10 6.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3504) TPR_11 PF13414.6 KIK56659.1 - 0.64 9.8 15.2 22 4.9 0.2 6.3 6 0 0 6 6 6 0 TPR repeat EXS PF03124.14 KIK56661.1 - 2.2e-59 201.4 15.4 3e-59 201.0 15.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KIK56661.1 - 2.2e-32 113.4 2.5 3.2e-32 112.9 2.5 1.2 1 0 0 1 1 1 1 SPX domain Glyco_transf_8C PF08437.10 KIK56661.1 - 0.1 12.7 1.1 0.36 11.0 1.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal SPX PF03105.19 KIK56662.1 - 7.2e-16 59.1 0.5 8.4e-16 58.9 0.5 1.1 1 0 0 1 1 1 1 SPX domain ABM PF03992.16 KIK56663.1 - 0.00061 19.8 0.0 0.055 13.6 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 KIK56663.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 ERG4_ERG24 PF01222.17 KIK56664.1 - 1.1e-134 449.5 3.2 1.3e-134 449.3 3.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KIK56664.1 - 4.4e-07 30.3 0.0 1.7e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIK56664.1 - 5.6e-06 26.0 0.9 9.2e-06 25.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK56664.1 - 0.00034 21.0 1.8 0.00056 20.3 0.0 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family tRNA_int_endo PF01974.17 KIK56665.1 - 3.5e-18 65.4 1.0 3.2e-17 62.3 1.0 2.2 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KIK56665.1 - 0.001 18.7 0.1 0.017 14.8 0.1 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Vps16_N PF04841.13 KIK56666.1 - 8.7e-85 284.9 0.0 1.1e-84 284.6 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KIK56666.1 - 1.2e-82 277.5 0.1 1.7e-82 277.1 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Arrestin_N PF00339.29 KIK56667.1 - 0.0011 19.0 0.5 1.7 8.7 0.0 3.6 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Sm_multidrug_ex PF06695.11 KIK56670.1 - 0.12 13.0 0.0 0.12 13.0 0.0 1.0 1 0 0 1 1 1 0 Putative small multi-drug export protein DUF3658 PF12395.8 KIK56672.1 - 0.14 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function AzlC PF03591.14 KIK56673.1 - 0.017 15.5 0.6 0.02 15.3 0.6 1.1 1 0 0 1 1 1 0 AzlC protein RmlD_sub_bind PF04321.17 KIK56677.1 - 5.2e-58 196.4 0.0 6.1e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIK56677.1 - 1.5e-24 86.8 0.0 1.8e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK56677.1 - 4.2e-10 39.5 0.0 5.4e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK56677.1 - 4.1e-08 32.7 0.1 3.2e-05 23.2 0.0 2.7 1 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIK56677.1 - 7e-06 25.4 0.0 0.001 18.3 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KIK56677.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 KIK56677.1 - 0.086 13.0 0.1 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LSM PF01423.22 KIK56678.1 - 6.6e-16 57.8 0.1 8.3e-16 57.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3294 PF07957.11 KIK56678.1 - 0.098 12.4 0.1 0.11 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) TPT PF03151.16 KIK56680.1 - 1.2e-15 57.6 22.0 1.7e-11 44.0 10.0 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF1118 PF06549.12 KIK56680.1 - 3.5 8.0 8.1 0.43 10.9 2.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1118) TPR_10 PF13374.6 KIK56681.1 - 1.2e-55 184.0 15.6 7.6e-14 51.1 0.0 6.6 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56681.1 - 3.3e-41 139.4 4.7 9.5e-10 38.6 0.1 5.1 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56681.1 - 8e-11 41.2 4.8 0.16 12.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56681.1 - 8.6e-10 38.3 12.6 0.057 13.8 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK56681.1 - 2.6e-09 36.6 7.5 0.2 12.0 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56681.1 - 6.3e-08 32.4 0.3 0.0058 16.1 0.0 2.4 1 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KIK56681.1 - 1.2e-07 31.3 8.8 0.46 10.4 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56681.1 - 7.4e-07 29.6 3.4 1.5 9.4 0.1 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56681.1 - 7.6e-07 28.8 2.1 1.8 8.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Mrpl_C PF18502.1 KIK56681.1 - 0.00013 22.2 2.8 6.5 7.1 0.0 4.6 1 1 4 5 5 5 1 54S ribosomal protein L8 C-terminal domain Uteroglobin PF01099.17 KIK56681.1 - 0.0069 16.7 1.1 20 5.6 0.0 3.7 1 1 2 4 4 4 0 Uteroglobin family Cytochrom_B562 PF07361.11 KIK56681.1 - 0.01 16.5 1.5 46 4.8 0.0 4.0 4 0 0 4 4 4 0 Cytochrome b562 DUF3531 PF12049.8 KIK56681.1 - 0.023 14.6 1.0 33 4.4 0.0 4.1 3 3 2 5 5 5 0 Protein of unknown function (DUF3531) MCPVI PF02993.14 KIK56681.1 - 0.047 13.5 0.2 13 5.6 0.0 2.9 1 1 3 4 4 4 0 Minor capsid protein VI WD40_alt PF14077.6 KIK56681.1 - 0.059 13.3 12.3 19 5.2 0.2 4.9 5 0 0 5 5 5 0 Alternative WD40 repeat motif DUF2298 PF10060.9 KIK56681.1 - 0.095 11.4 0.9 2.7 6.6 0.1 2.7 2 1 1 3 3 3 0 Uncharacterized membrane protein (DUF2298) AAA_16 PF13191.6 KIK56682.1 - 0.024 15.0 0.0 0.073 13.5 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KIK56682.1 - 0.047 14.0 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK56682.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_N PF01194.17 KIK56687.1 - 4.3e-32 110.2 0.6 5.1e-32 110.0 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit CAMSAP_CH PF11971.8 KIK56687.1 - 0.033 14.0 0.1 0.043 13.7 0.1 1.1 1 0 0 1 1 1 0 CAMSAP CH domain DUF2087 PF09860.9 KIK56687.1 - 0.033 14.3 0.3 0.04 14.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Mu-like_Com PF10122.9 KIK56687.1 - 0.053 13.0 1.2 0.31 10.5 1.2 2.0 1 1 0 1 1 1 0 Mu-like prophage protein Com Sacchrp_dh_C PF16653.5 KIK56688.1 - 3e-22 80.0 0.0 4.6e-21 76.1 0.0 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KIK56688.1 - 1.8e-20 73.2 0.0 6.4e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KIK56688.1 - 3.8e-08 33.1 0.1 1.2e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain AAA_29 PF13555.6 KIK56689.1 - 0.91 9.3 4.3 4.7 7.0 0.6 2.6 2 1 0 2 2 2 0 P-loop containing region of AAA domain TPR_10 PF13374.6 KIK56690.1 - 6.3e-96 312.0 20.8 1.5e-11 43.8 0.0 10.3 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK56690.1 - 2.2e-61 204.1 18.2 2.6e-12 46.8 1.3 8.5 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK56690.1 - 1.1e-16 61.2 2.6 0.0053 16.2 0.0 4.0 1 1 3 4 4 4 4 MalT-like TPR region TPR_8 PF13181.6 KIK56690.1 - 1.4e-14 53.0 15.9 0.19 12.0 0.2 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIK56690.1 - 4.5e-10 39.2 21.9 0.55 10.7 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK56690.1 - 4.2e-09 35.8 18.6 2.3 8.2 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK56690.1 - 2.5e-07 30.2 12.6 1.4 9.1 0.1 8.7 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK56690.1 - 4.1e-07 30.0 0.0 13 6.8 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK56690.1 - 2.1e-05 24.9 7.1 12 6.5 0.2 6.1 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK56690.1 - 0.0014 18.6 16.3 17 5.9 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK56690.1 - 0.0053 17.4 4.1 19 6.0 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat AAA_19 PF13245.6 KIK56690.1 - 0.22 11.8 1.6 19 5.6 1.7 3.5 1 1 0 1 1 1 0 AAA domain DUF2563 PF10817.8 KIK56690.1 - 0.52 10.9 3.8 9.3 6.9 0.0 3.8 3 2 2 5 5 5 0 Protein of unknown function (DUF2563) TPR_14 PF13428.6 KIK56690.1 - 0.61 11.1 7.0 2.5e+02 2.9 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat FATC PF02260.20 KIK56690.1 - 8.7 6.3 6.4 1.4e+02 2.4 0.2 5.2 6 0 0 6 6 6 0 FATC domain tRNA-synt_2b PF00587.25 KIK56691.1 - 5.6e-35 120.9 0.1 9.2e-34 117.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIK56691.1 - 8.6e-19 67.8 4.7 8.6e-19 67.8 4.7 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_His PF13393.6 KIK56691.1 - 0.024 13.9 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PriC PF07445.12 KIK56691.1 - 0.06 13.3 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Primosomal replication protein priC Arc_C PF18162.1 KIK56691.1 - 0.099 12.5 0.8 7.7 6.4 0.3 2.8 3 0 0 3 3 3 0 Arc C-lobe DUF4946 PF16304.5 KIK56691.1 - 0.11 12.3 0.8 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4946) Histone_H2A_C PF16211.5 KIK56692.1 - 4.5e-17 61.5 1.0 8.5e-17 60.6 1.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KIK56692.1 - 1e-16 61.5 0.0 1.3e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK56692.1 - 1.4e-06 28.5 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_9 PF13371.6 KIK56693.1 - 0.00062 19.9 0.3 0.0016 18.6 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK56693.1 - 0.058 14.2 1.3 0.46 11.4 1.6 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 KIK56696.1 - 8.1e-09 35.4 0.2 9.6e-06 25.3 0.0 2.1 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 KIK56697.1 - 3.5e-11 43.0 3.4 5e-11 42.5 2.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KIK56697.1 - 0.032 13.6 1.3 0.032 13.6 1.3 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Viral_alk_exo PF01771.17 KIK56697.1 - 0.21 10.4 0.1 0.31 9.8 0.1 1.3 1 1 0 1 1 1 0 Viral alkaline exonuclease Sec23_trunk PF04811.15 KIK56698.1 - 6.6e-70 235.4 0.0 1e-69 234.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIK56698.1 - 2.1e-23 82.1 0.1 4.5e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KIK56698.1 - 1.8e-16 60.7 0.1 3.6e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIK56698.1 - 4.4e-16 58.6 7.4 7.6e-16 57.9 7.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIK56698.1 - 4e-08 33.0 0.0 8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 KIK56698.1 - 0.00037 20.5 2.0 0.00037 20.5 2.0 2.3 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 KIK56698.1 - 0.0061 15.9 0.8 0.013 14.9 0.8 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sugar_tr PF00083.24 KIK56699.1 - 1.6e-112 376.7 21.2 1.9e-112 376.4 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK56699.1 - 3.8e-25 88.5 40.3 5.5e-19 68.3 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CotE PF10628.9 KIK56702.1 - 0.013 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) MFS_1 PF07690.16 KIK56703.1 - 7e-16 58.1 39.9 4.1e-14 52.3 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KIK56704.1 - 5.1e-10 38.8 0.0 1.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK56704.1 - 3.8e-05 23.7 13.9 7.4e-05 22.8 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEPN_SAV_6107 PF18726.1 KIK56704.1 - 0.06 13.8 0.9 0.35 11.4 0.0 2.7 3 1 0 3 3 3 0 SAV_6107-like HEPN PspB PF06667.12 KIK56704.1 - 0.88 9.7 2.6 10 6.2 0.3 2.8 3 0 0 3 3 3 0 Phage shock protein B WSC PF01822.19 KIK56705.1 - 2e-32 111.2 23.7 4.1e-16 58.9 7.6 2.5 2 0 0 2 2 2 2 WSC domain DUF4510 PF14971.6 KIK56707.1 - 0.0065 16.8 0.1 0.008 16.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) Peptidase_S49_N PF08496.10 KIK56708.1 - 0.0057 16.7 0.7 0.012 15.7 0.7 1.5 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK56708.1 - 0.043 14.3 8.7 0.07 13.6 8.7 1.4 1 0 0 1 1 1 0 Fez1 PKcGMP_CC PF16808.5 KIK56708.1 - 0.08 12.8 12.1 0.43 10.5 0.5 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK56708.1 - 0.65 10.4 10.9 2 8.8 3.8 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF641 PF04859.12 KIK56708.1 - 1.1 9.7 10.0 0.22 11.8 3.2 2.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 KIK56708.1 - 1.4 9.0 11.9 1.6 8.7 6.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4239 PF14023.6 KIK56708.1 - 1.4 8.6 4.0 4.9 6.8 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) V_ATPase_I PF01496.19 KIK56708.1 - 2.5 5.9 6.5 3.5 5.4 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PEP-utilisers_N PF05524.13 KIK56708.1 - 2.7 8.2 5.9 8.7 6.5 4.5 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF745 PF05335.13 KIK56709.1 - 0.3 10.8 2.4 8.8 6.0 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) FAM76 PF16046.5 KIK56712.1 - 0.0056 16.1 2.7 0.0074 15.7 2.7 1.1 1 0 0 1 1 1 1 FAM76 protein DASH_Spc34 PF08657.10 KIK56712.1 - 0.0099 15.7 0.3 0.013 15.4 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Sec2p PF06428.11 KIK56712.1 - 0.01 15.8 3.8 0.01 15.8 3.8 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Exonuc_VII_L PF02601.15 KIK56712.1 - 0.036 13.6 2.6 0.051 13.1 2.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 KIK56712.1 - 0.047 14.3 5.9 1.4 9.6 1.1 2.9 1 1 1 2 2 2 0 SlyX TBCC_N PF16752.5 KIK56712.1 - 0.083 13.3 5.9 0.14 12.6 5.9 1.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain FidL_like PF15941.5 KIK56712.1 - 0.12 12.8 0.7 0.34 11.4 0.7 1.8 1 0 0 1 1 1 0 FidL-like putative membrane protein Cast PF10174.9 KIK56712.1 - 0.13 10.4 9.4 0.34 9.1 9.4 1.5 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Csm1_N PF18504.1 KIK56712.1 - 1.6 9.1 6.4 2.5 8.5 1.7 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain CCDC-167 PF15188.6 KIK56712.1 - 6.2 7.2 9.9 34 4.9 9.9 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 KIK56712.1 - 7.5 5.8 12.4 0.21 10.9 4.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KDZ PF18758.1 KIK56715.1 - 1.1e-26 93.9 0.6 1.4e-26 93.5 0.6 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Integrase_H2C2 PF17921.1 KIK56719.1 - 1.2e-09 38.1 0.4 1.6e-09 37.7 0.4 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KIK56719.1 - 0.013 15.7 0.2 0.015 15.5 0.2 1.2 1 0 0 1 1 1 0 H2C2 zinc finger Ank_2 PF12796.7 KIK56722.1 - 2.6e-12 47.1 0.2 1.2e-10 41.8 0.2 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK56722.1 - 8.2e-11 41.8 0.1 0.0015 18.9 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KIK56722.1 - 2.7e-10 40.6 0.5 4.6e-08 33.5 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK56722.1 - 2.2e-09 36.8 0.1 0.0081 16.6 0.0 4.2 4 0 0 4 4 3 2 Ankyrin repeat NACHT PF05729.12 KIK56722.1 - 4.4e-06 26.7 0.0 1.4e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KIK56722.1 - 6.7e-05 23.1 3.1 0.013 15.8 0.3 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) NB-ARC PF00931.22 KIK56722.1 - 0.00018 20.8 0.1 0.00043 19.6 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK56722.1 - 0.041 14.1 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK56722.1 - 0.057 13.8 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF1843 PF08898.10 KIK56722.1 - 0.87 10.1 4.1 5.6 7.5 0.1 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF1843) DUF2175 PF09943.9 KIK56722.1 - 0.93 9.8 6.3 19 5.6 0.3 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4208 PF13907.6 KIK56722.1 - 0.97 9.9 3.7 2.7 8.5 0.1 3.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4208) Ribonuclease_3 PF00636.26 KIK56723.1 - 0.05 14.2 0.0 2.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK56723.1 - 0.098 12.8 0.0 9.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease-III-like Abhydrolase_1 PF00561.20 KIK56726.1 - 0.0039 16.9 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK56726.1 - 0.0066 17.1 0.0 0.0083 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK56726.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-CCHC PF00098.23 KIK56728.1 - 0.012 15.6 3.1 0.012 15.6 3.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK56728.1 - 0.21 11.4 1.8 0.36 10.7 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Ank_2 PF12796.7 KIK56733.1 - 1e-08 35.6 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK56733.1 - 3.5e-05 24.0 0.0 0.31 11.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIK56733.1 - 0.00057 20.1 0.0 1.1 10.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KIK56733.1 - 0.00066 20.2 0.2 0.014 16.0 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK56733.1 - 0.043 14.1 0.2 4.8 7.6 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) NACHT PF05729.12 KIK56734.1 - 4.1e-06 26.8 0.0 1.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK56734.1 - 3.3e-05 23.2 0.0 7.2e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK56734.1 - 0.0077 16.6 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK56734.1 - 0.018 15.3 0.0 0.041 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIK56734.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK56734.1 - 0.027 14.5 0.0 0.41 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK56734.1 - 0.057 13.3 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK56734.1 - 0.074 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK56734.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1658 PF07871.11 KIK56735.1 - 1.2 9.2 4.2 0.96 9.5 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1658) Peptidase_C92 PF05708.12 KIK56738.1 - 0.039 14.0 0.1 0.045 13.8 0.1 1.1 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Sad1_UNC PF07738.13 KIK56739.1 - 2.9e-09 37.0 0.1 4.1e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DOT1 PF08123.13 KIK56740.1 - 2.1e-16 60.1 0.0 2.2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KIK56740.1 - 0.031 14.9 0.1 0.041 14.5 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIK56740.1 - 0.073 12.5 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KIK56740.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.0 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RNA_pol_3_Rpc31 PF11705.8 KIK56743.1 - 0.0039 17.5 15.0 0.0039 17.5 15.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 KIK56743.1 - 0.0071 16.0 13.8 0.0071 16.0 13.8 1.1 1 0 0 1 1 1 1 PPP4R2 RAB3GAP2_C PF14656.6 KIK56743.1 - 0.049 11.9 0.7 0.048 11.9 0.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF913 PF06025.12 KIK56743.1 - 0.085 11.8 1.1 0.072 12.1 1.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5520 PF17658.1 KIK56743.1 - 0.12 11.4 3.6 0.14 11.2 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) V_ATPase_I PF01496.19 KIK56743.1 - 0.16 9.8 1.6 0.14 10.1 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NOA36 PF06524.12 KIK56743.1 - 0.17 11.2 20.2 0.19 11.0 20.2 1.1 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 KIK56743.1 - 0.2 10.4 0.6 0.16 10.7 0.6 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 KIK56743.1 - 0.26 9.4 19.5 0.29 9.3 19.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIK56743.1 - 0.42 10.0 17.5 0.44 9.9 17.5 1.1 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 KIK56743.1 - 0.43 10.2 21.0 0.49 10.1 21.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PI3K_1B_p101 PF10486.9 KIK56743.1 - 0.72 7.6 4.5 0.61 7.8 4.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4820 PF16091.5 KIK56743.1 - 3.9 6.8 8.6 4.4 6.6 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 KIK56743.1 - 7.2 5.7 15.9 8.3 5.5 15.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YbaB_DNA_bd PF02575.16 KIK56745.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family BNR PF02012.20 KIK56748.1 - 0.1 12.7 0.3 0.25 11.5 0.3 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Arm PF00514.23 KIK56750.1 - 2.2e-73 240.3 17.5 4.9e-14 51.8 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK56750.1 - 4.3e-22 78.2 3.1 7.5e-09 35.9 0.1 6.3 4 1 2 6 6 6 5 HEAT-like repeat Arm_3 PF16186.5 KIK56750.1 - 1.3e-17 63.0 0.4 4.3e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KIK56750.1 - 1.6e-13 50.8 0.0 6.1e-05 23.3 0.0 4.9 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 KIK56750.1 - 3e-12 45.7 1.7 0.00054 20.0 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 KIK56750.1 - 0.00025 20.6 0.0 0.15 11.5 0.0 3.5 2 1 1 3 3 3 1 Armadillo-like NopRA1 PF16201.5 KIK56750.1 - 0.0053 16.4 0.0 24 4.4 0.0 4.0 2 2 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 V-ATPase_H_C PF11698.8 KIK56750.1 - 0.014 15.5 0.1 2.8 8.1 0.0 3.1 3 2 1 4 4 4 0 V-ATPase subunit H HEAT_PBS PF03130.16 KIK56750.1 - 0.027 15.1 2.4 0.53 11.1 0.1 3.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat IFRD PF05004.13 KIK56750.1 - 0.029 13.5 0.1 4.9 6.2 0.0 3.0 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) CTNNBL PF08216.11 KIK56750.1 - 0.036 14.3 0.2 21 5.3 0.0 3.7 4 0 0 4 4 3 0 Catenin-beta-like, Arm-motif containing nuclear IBB PF01749.20 KIK56750.1 - 0.046 14.2 1.7 5.4 7.5 0.0 2.5 1 1 1 2 2 2 0 Importin beta binding domain RICTOR_V PF14668.6 KIK56750.1 - 0.079 13.2 0.9 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 BRCT PF00533.26 KIK56751.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Sarcoglycan_2 PF05510.13 KIK56751.1 - 0.045 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon BRCT_2 PF16589.5 KIK56751.1 - 0.068 13.6 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BTB PF00651.31 KIK56752.1 - 7.9e-05 22.9 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2015 PF09435.10 KIK56754.1 - 8.3e-26 90.0 0.1 9.6e-26 89.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Transposase_21 PF02992.14 KIK56756.1 - 2.1e-06 27.1 0.0 2.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Importin_rep_2 PF18786.1 KIK56758.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Importin 13 repeat Sad1_UNC PF07738.13 KIK56760.1 - 2.5e-09 37.2 0.1 3.3e-05 23.9 0.0 2.3 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal NACHT PF05729.12 KIK56761.1 - 0.0015 18.5 0.1 0.0035 17.3 0.0 1.6 2 0 0 2 2 2 1 NACHT domain Tymo_45kd_70kd PF03251.13 KIK56761.1 - 0.03 13.3 0.1 0.055 12.4 0.1 1.4 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein Agenet PF05641.12 KIK56761.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Agenet domain KOW PF00467.29 KIK56765.1 - 0.00054 19.8 10.4 0.81 9.7 0.4 5.2 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 KIK56765.1 - 0.047 14.0 0.2 1.8 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Spt5_N PF11942.8 KIK56766.1 - 4.8e-07 30.7 0.9 6e-07 30.4 0.9 1.1 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic PF14632.6 KIK56766.1 - 0.0022 18.6 1.8 0.0026 18.3 1.8 1.2 1 0 0 1 1 1 1 Acidic N-terminal SPT6 DUF4795 PF16043.5 KIK56768.1 - 0.01 15.4 3.0 0.026 14.1 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Sec34 PF04136.15 KIK56768.1 - 0.016 15.1 7.7 0.043 13.7 3.5 2.7 3 0 0 3 3 3 0 Sec34-like family CHASE3 PF05227.13 KIK56768.1 - 0.018 14.9 0.8 0.046 13.6 0.8 1.6 1 0 0 1 1 1 0 CHASE3 domain FlaC_arch PF05377.11 KIK56768.1 - 0.32 11.4 5.7 20 5.7 0.3 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KIK56768.1 - 4 7.7 8.7 1.9 8.7 2.7 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4404 PF14357.6 KIK56768.1 - 4.9 7.9 6.3 15 6.3 1.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DOT1 PF08123.13 KIK56769.1 - 1.3e-44 152.2 0.0 1.5e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 KIK56769.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK56769.1 - 0.012 16.3 0.0 0.021 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Chromo PF00385.24 KIK56771.1 - 0.0013 18.6 0.8 0.0023 17.8 0.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NPL PF17800.1 KIK56772.1 - 8.8e-05 23.0 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain SpoIIP PF07454.11 KIK56773.1 - 0.014 14.8 1.6 0.033 13.7 1.6 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 KIK56773.1 - 0.78 8.5 4.1 1.7 7.4 4.1 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_3_Rpc31 PF11705.8 KIK56773.1 - 2.7 8.2 30.9 0.05 13.8 18.6 3.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2150 PF09920.9 KIK56774.1 - 0.046 13.7 0.7 0.073 13.0 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Antimicrobial_3 PF08025.11 KIK56774.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Spider antimicrobial peptide ANAPC4_WD40 PF12894.7 KIK56775.1 - 9.6e-05 22.6 0.0 0.013 15.8 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK56775.1 - 0.2 12.6 5.3 5.6 8.0 0.2 3.9 2 1 2 4 4 4 0 WD domain, G-beta repeat NPL PF17800.1 KIK56776.1 - 2.9e-06 27.8 0.0 2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Nucleoplasmin-like domain Defb50 PF17546.2 KIK56778.1 - 0.13 12.2 0.2 0.22 11.5 0.2 1.3 1 0 0 1 1 1 0 Beta defensin 50 AKAP7_NLS PF10469.9 KIK56779.1 - 0.036 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Plavaka PF18759.1 KIK56782.1 - 1.1e-15 57.8 0.1 1.2e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase CLLAC PF15675.5 KIK56782.1 - 0.024 14.2 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain Pkinase PF00069.25 KIK56784.1 - 2e-09 37.2 0.0 5.1e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK56784.1 - 0.0036 16.6 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 KIK56784.1 - 0.045 13.3 0.1 0.072 12.7 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cnd1 PF12717.7 KIK56786.1 - 0.021 14.9 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TT_ORF2 PF02957.15 KIK56786.1 - 0.12 13.3 3.5 0.2 12.6 3.5 1.4 1 0 0 1 1 1 0 TT viral ORF2 Toxin_28 PF08115.11 KIK56786.1 - 0.17 11.7 0.8 0.39 10.6 0.8 1.6 1 0 0 1 1 1 0 SFI toxin family GAGA_bind PF06217.12 KIK56792.1 - 0.3 11.3 4.7 0.37 11.0 4.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4218 PF13960.6 KIK56794.1 - 0.0031 17.1 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDT PF02791.17 KIK56794.1 - 0.091 13.1 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 DDT domain PhnJ PF06007.11 KIK56795.1 - 0.13 11.3 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Transposase_21 PF02992.14 KIK56796.1 - 2e-08 33.7 0.0 2.1e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 DUF4428 PF14471.6 KIK56797.1 - 0.077 12.9 0.8 7 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ANAPC4_WD40 PF12894.7 KIK56798.1 - 2.3e-05 24.6 0.0 0.0041 17.4 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KIK56798.1 - 0.059 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KIK56798.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.9 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 KIK56798.1 - 4.2 8.4 14.7 3.1 8.8 1.4 5.0 5 1 0 5 5 5 0 WD domain, G-beta repeat DASH_Dad2 PF08654.10 KIK56799.1 - 0.63 10.5 8.3 1.9 9.0 0.9 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad2 NOC3p PF07540.11 KIK56799.1 - 0.86 10.1 0.0 0.86 10.1 0.0 2.8 3 0 0 3 3 3 0 Nucleolar complex-associated protein COG2 PF06148.11 KIK56799.1 - 2.5 8.2 12.1 2.3 8.3 1.4 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4939 PF16297.5 KIK56800.1 - 5.8e-05 22.9 0.4 0.00011 22.1 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KIK56800.1 - 0.0091 16.3 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DEC-1_N PF04625.13 KIK56802.1 - 0.053 12.5 9.8 0.061 12.3 9.8 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NACHT PF05729.12 KIK56806.1 - 2e-07 31.1 0.0 4.8e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK56806.1 - 2.1e-06 27.1 0.1 4.3e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK56806.1 - 0.00075 19.9 0.0 0.0017 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KIK56806.1 - 0.0024 17.9 0.0 0.092 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIK56806.1 - 0.021 14.1 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KIK56806.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK56806.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK56806.1 - 0.046 14.1 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Retrotrans_gag PF03732.17 KIK56809.1 - 1.5e-08 34.7 0.1 2.5e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein FAM76 PF16046.5 KIK56813.1 - 0.00074 19.0 0.6 0.00098 18.6 0.6 1.1 1 0 0 1 1 1 1 FAM76 protein MPS2 PF17060.5 KIK56813.1 - 0.0018 17.6 0.5 0.0026 17.1 0.5 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 HMMR_N PF15905.5 KIK56813.1 - 0.009 15.5 1.9 0.013 15.0 1.9 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK56813.1 - 0.018 14.0 1.9 0.024 13.5 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KIK56813.1 - 0.018 15.4 5.7 0.13 12.6 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Peptidase_S49_N PF08496.10 KIK56813.1 - 0.02 15.0 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF724 PF05266.14 KIK56813.1 - 0.093 12.5 3.2 0.14 12.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PKcGMP_CC PF16808.5 KIK56813.1 - 0.098 12.5 3.5 2.9 7.8 0.7 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LRS4 PF10422.9 KIK56813.1 - 0.12 12.0 2.3 0.16 11.5 2.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Syntaphilin PF15290.6 KIK56813.1 - 0.28 10.8 0.1 0.28 10.8 0.1 2.0 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Phage_GP20 PF06810.11 KIK56813.1 - 2.8 7.7 7.1 5.5 6.8 1.3 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 Sec2p PF06428.11 KIK56813.1 - 3.3 7.7 8.8 2.1 8.4 2.2 2.5 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p ResIII PF04851.15 KIK56814.1 - 0.074 13.1 0.0 0.074 13.1 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRF-TF PF00319.18 KIK56814.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Plavaka PF18759.1 KIK56820.1 - 1.7e-15 57.1 1.2 1.9e-15 56.9 1.2 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK56821.1 - 4.3e-18 65.6 0.0 5e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK56823.1 - 3.5e-91 305.8 0.1 4.1e-91 305.6 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase CLLAC PF15675.5 KIK56823.1 - 0.047 13.3 0.1 0.17 11.5 0.1 2.0 1 0 0 1 1 1 0 CLLAC-motif containing domain Transthyretin PF00576.21 KIK56824.1 - 0.052 14.2 0.1 0.062 14.0 0.1 1.1 1 0 0 1 1 1 0 HIUase/Transthyretin family Cauli_VI PF01693.16 KIK56827.1 - 0.00041 20.6 0.1 0.00071 19.8 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Tankyrase_bdg_C PF15327.6 KIK56827.1 - 0.082 13.4 3.8 0.11 12.9 3.8 1.1 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Spc29 PF17082.5 KIK56828.1 - 0.00072 19.5 0.3 0.00095 19.1 0.3 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF948 PF06103.11 KIK56828.1 - 0.13 12.5 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Retrotran_gag_3 PF14244.6 KIK56830.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3922 PF13059.6 KIK56830.1 - 0.021 15.2 0.2 0.021 15.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) Retrotran_gag_2 PF14223.6 KIK56830.1 - 0.05 13.3 0.8 0.11 12.1 0.8 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Forkhead PF00250.18 KIK56832.1 - 4.8e-10 39.6 0.0 5.1e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain Peptidase_C48 PF02902.19 KIK56834.1 - 4.6e-08 33.2 0.0 7.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TCR_zetazeta PF11628.8 KIK56836.1 - 0.012 15.2 1.0 0.023 14.4 1.0 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain UPF0154 PF03672.13 KIK56836.1 - 0.02 14.9 0.4 0.036 14.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) CHCH PF06747.13 KIK56837.1 - 0.0016 18.5 1.2 0.0028 17.8 1.2 1.4 1 1 0 1 1 1 1 CHCH domain FMO-like PF00743.19 KIK56840.1 - 0.00032 19.2 0.0 0.00063 18.3 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KIK56840.1 - 0.003 17.6 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIK56840.1 - 0.0038 16.6 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KIK56840.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MCRA PF06100.11 KIK56840.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_3 PF01494.19 KIK56841.1 - 1.2e-17 64.2 0.0 2.6e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK56841.1 - 0.0011 19.1 1.0 0.0029 17.8 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK56841.1 - 0.019 14.2 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIK56841.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 KIK56841.1 - 0.06 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK56841.1 - 0.068 12.0 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DMA PF03474.14 KIK56841.1 - 0.18 11.4 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 DMRTA motif MBOAT_2 PF13813.6 KIK56842.1 - 2.1e-22 79.2 2.4 2.1e-22 79.2 2.4 2.5 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family SAPS PF04499.15 KIK56843.1 - 0.057 12.2 3.2 0.073 11.8 3.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 KIK56843.1 - 5 5.6 5.4 7.4 5.0 5.4 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 KIK56843.1 - 6.9 5.3 6.5 11 4.7 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AATF-Che1 PF13339.6 KIK56845.1 - 0.038 14.7 1.6 0.057 14.1 1.6 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Cauli_VI PF01693.16 KIK56846.1 - 1.8e-07 31.4 0.0 2.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin KOW PF00467.29 KIK56847.1 - 0.0076 16.2 0.3 0.23 11.5 0.1 2.6 2 1 0 2 2 2 1 KOW motif Baculo_19 PF04798.12 KIK56847.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Spt5-NGN PF03439.13 KIK56847.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section DUF4335 PF14233.6 KIK56850.1 - 0.074 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) MBOAT_2 PF13813.6 KIK56851.1 - 6.7e-41 138.4 9.5 7.6e-22 77.4 0.2 4.6 4 0 0 4 4 4 3 Membrane bound O-acyl transferase family SbmA_BacA PF05992.12 KIK56851.1 - 0.00066 19.2 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 SbmA/BacA-like family DUF2492 PF10678.9 KIK56851.1 - 0.0039 17.4 0.0 5 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2492) DUF3775 PF12616.8 KIK56851.1 - 0.17 12.0 0.5 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) MBOAT_2 PF13813.6 KIK56852.1 - 1.7e-22 79.5 0.3 2.2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family BppL_N PF18338.1 KIK56852.1 - 0.0025 17.5 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 2 Lower baseplate protein N-terminal domain DUF3701 PF12482.8 KIK56852.1 - 0.0066 16.5 0.4 5 7.3 0.1 3.1 2 1 0 2 2 2 2 Phage integrase protein SbmA_BacA PF05992.12 KIK56852.1 - 0.0071 15.8 0.1 3.4 7.0 0.0 2.1 2 0 0 2 2 2 2 SbmA/BacA-like family DUF2492 PF10678.9 KIK56852.1 - 0.01 16.1 0.0 7.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) MBOAT_2 PF13813.6 KIK56853.1 - 5e-21 74.8 0.6 1.4e-20 73.3 0.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4401 PF14351.6 KIK56853.1 - 0.0014 18.0 0.6 0.0027 17.1 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4401) MBOAT_2 PF13813.6 KIK56854.1 - 9.4e-21 73.9 4.8 3.8e-20 72.0 4.8 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Retrotran_gag_2 PF14223.6 KIK56856.1 - 0.00036 20.2 0.1 0.00056 19.6 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1414 PF07208.11 KIK56856.1 - 0.023 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Epiglycanin_TR PF05647.11 KIK56856.1 - 0.32 10.9 4.5 0.48 10.4 4.5 1.2 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Utp14 PF04615.13 KIK56858.1 - 2.6e-200 667.8 66.6 2.6e-200 667.8 66.6 2.2 1 1 1 2 2 2 1 Utp14 protein WD40 PF00400.32 KIK56859.1 - 1.2e-101 329.8 56.7 1.2e-09 38.6 0.4 13.5 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56859.1 - 6e-40 135.4 2.7 0.0089 16.3 0.0 11.2 1 1 9 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56859.1 - 2.7e-15 55.9 14.1 2.7 8.0 0.0 11.6 12 0 0 12 12 12 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56859.1 - 7e-12 44.9 3.1 0.83 8.5 0.0 9.6 2 2 7 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK56859.1 - 2.6e-08 34.0 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Gmad1 PF10647.9 KIK56859.1 - 1.9e-07 31.1 2.9 2.7 7.7 0.0 6.6 3 3 5 8 8 8 1 Lipoprotein LpqB beta-propeller domain Frtz PF11768.8 KIK56859.1 - 4.2e-07 28.7 0.0 3.5 5.8 0.0 6.0 3 3 2 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK56859.1 - 8.3e-07 29.5 0.0 2.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK56859.1 - 1.6e-06 28.6 0.0 5.2e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40_like PF17005.5 KIK56859.1 - 1.6e-06 27.7 0.0 12 5.1 0.0 7.2 6 2 0 8 8 8 0 WD40-like domain Proteasome_A_N PF10584.9 KIK56859.1 - 0.0035 17.0 13.1 40 4.0 0.0 8.0 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KIK56859.1 - 0.0039 15.8 0.1 3.6 6.0 0.0 3.2 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KIK56859.1 - 0.0055 15.5 4.2 1.7 7.3 0.2 5.4 4 2 3 7 7 7 1 Nup133 N terminal like AAA_7 PF12775.7 KIK56859.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KIK56859.1 - 0.0079 16.5 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Nup160 PF11715.8 KIK56859.1 - 0.031 12.9 0.6 12 4.4 0.0 4.3 4 2 1 6 6 6 0 Nucleoporin Nup120/160 ATPase_2 PF01637.18 KIK56859.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KIK56859.1 - 0.083 12.0 0.1 0.46 9.6 0.0 2.2 3 0 0 3 3 3 0 PIF1-like helicase NB-ARC PF00931.22 KIK56859.1 - 0.091 11.9 0.0 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain PQQ_3 PF13570.6 KIK56859.1 - 9.8 6.8 6.4 13 6.5 0.3 4.0 5 1 1 6 6 3 0 PQQ-like domain DUF4248 PF14053.6 KIK56861.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4248) Terpene_synth_C PF03936.16 KIK56862.1 - 1e-07 31.6 0.0 2.8e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KIK56862.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal Lipase_GDSL PF00657.22 KIK56863.1 - 1.2e-07 32.0 0.0 1.8e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK56863.1 - 0.0051 17.2 0.3 0.013 15.9 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 KIK56864.1 - 2.3e-25 89.3 30.2 3.4e-21 75.6 8.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK56864.1 - 1.9e-05 23.8 10.7 3.7e-05 22.8 10.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK56864.1 - 0.0033 16.3 16.5 0.017 14.0 0.4 3.3 2 1 1 3 3 3 2 MFS_1 like family Ank_2 PF12796.7 KIK56865.1 - 1.9e-34 118.1 0.9 1.9e-14 54.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK56865.1 - 6.7e-21 74.4 0.7 1.2e-08 35.3 0.0 3.7 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK56865.1 - 4.5e-18 63.5 0.0 0.0028 18.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KIK56865.1 - 1.3e-16 60.2 1.3 0.0017 18.8 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KIK56865.1 - 1.9e-13 50.3 0.1 0.017 15.4 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 KIK56865.1 - 0.017 15.6 1.9 22 5.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) MFS_1 PF07690.16 KIK56866.1 - 2.6e-11 43.1 6.6 2.9e-11 42.9 6.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK56866.1 - 0.00037 19.5 3.4 0.00043 19.3 3.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK56866.1 - 0.002 17.1 0.5 0.0026 16.7 0.5 1.2 1 0 0 1 1 1 1 MFS_1 like family zf-HYPF PF07503.12 KIK56867.1 - 0.21 11.4 0.1 0.51 10.2 0.0 1.6 2 0 0 2 2 2 0 HypF finger RVT_1 PF00078.27 KIK56868.1 - 0.0078 15.8 0.0 0.008 15.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KIK56869.1 - 2.2e-64 211.8 27.8 5.3e-11 42.9 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56869.1 - 2.1e-31 108.1 0.9 0.00022 21.5 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56869.1 - 1.3e-11 44.1 1.0 1 9.4 0.0 6.3 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56869.1 - 7.4e-10 38.3 0.3 1.5 7.7 0.0 5.9 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK56869.1 - 2.1e-06 27.3 0.0 0.23 10.7 0.0 4.5 3 2 2 5 5 5 2 WD40-like domain Nucleoporin_N PF08801.11 KIK56869.1 - 3.7e-06 26.0 3.2 0.0014 17.4 1.8 3.2 1 1 1 2 2 2 1 Nup133 N terminal like DUF4072 PF13284.6 KIK56869.1 - 3.4e-05 24.2 1.5 19 5.8 0.1 6.1 6 1 1 7 7 7 0 Domain of unknown function (DUF4072) BBS2_Mid PF14783.6 KIK56869.1 - 4.2e-05 23.5 0.1 27 4.9 0.0 5.6 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KIK56869.1 - 5e-05 23.0 0.0 14 5.8 0.0 5.6 6 0 0 6 6 6 0 PQQ enzyme repeat Frtz PF11768.8 KIK56869.1 - 8e-05 21.1 0.0 0.33 9.2 0.0 3.7 1 1 3 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz Pyr_redox_dim PF02852.22 KIK56869.1 - 8.9e-05 22.7 0.0 3.3 8.0 0.0 3.8 2 2 3 5 5 5 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PQQ_3 PF13570.6 KIK56869.1 - 0.00029 21.2 1.1 6.2 7.5 0.0 4.8 3 3 2 5 5 5 1 PQQ-like domain DUF2239 PF09998.9 KIK56869.1 - 0.00047 20.0 0.0 12 5.7 0.0 4.4 1 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2239) Cuticle_4 PF15955.5 KIK56869.1 - 0.014 16.1 4.1 53 4.6 0.2 4.7 5 0 0 5 5 5 0 Cuticle protein DUF1513 PF07433.11 KIK56869.1 - 0.039 13.0 0.3 2.1 7.3 0.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) nos_propeller PF18764.1 KIK56869.1 - 0.04 13.8 0.2 22 5.0 0.0 4.1 5 0 0 5 5 5 0 Nitrous oxide reductase propeller repeat Cytochrom_D1 PF02239.16 KIK56869.1 - 0.087 11.3 0.2 0.36 9.3 0.1 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain Peptidase_S9_N PF02897.15 KIK56869.1 - 0.098 11.4 0.0 2.2 7.0 0.0 2.9 1 1 3 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Big_7 PF17957.1 KIK56869.1 - 0.19 12.5 2.5 25 5.7 0.1 4.1 3 2 0 4 4 4 0 Bacterial Ig domain Proteasome_A_N PF10584.9 KIK56869.1 - 2.3 8.0 9.3 9.8 6.0 0.0 4.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK56870.1 - 3.1e-44 148.1 11.4 1.3e-08 35.3 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56870.1 - 3.4e-20 72.2 0.1 0.0085 16.4 0.0 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK56870.1 - 2.2e-10 40.7 0.0 4.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK56870.1 - 4.9e-08 33.6 0.0 1.2e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 KIK56870.1 - 3e-07 30.2 1.0 1.6 8.8 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat AAA PF00004.29 KIK56870.1 - 4.7e-07 30.3 0.0 1.5e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 KIK56870.1 - 1.7e-06 27.3 0.7 0.6 9.0 0.0 4.6 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NB-ARC PF00931.22 KIK56870.1 - 0.0023 17.1 0.0 0.038 13.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.17 KIK56870.1 - 0.0037 17.0 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein PIF1 PF05970.14 KIK56870.1 - 0.0045 16.2 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 PIF1-like helicase KAP_NTPase PF07693.14 KIK56870.1 - 0.0047 16.2 0.3 0.21 10.8 0.0 2.7 2 1 1 3 3 3 1 KAP family P-loop domain AAA_22 PF13401.6 KIK56870.1 - 0.0057 16.9 0.0 0.028 14.7 0.0 2.0 1 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK56870.1 - 0.0084 16.0 0.0 0.024 14.6 0.0 1.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Torsin PF06309.11 KIK56870.1 - 0.015 15.4 0.1 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 Torsin WD40_like PF17005.5 KIK56870.1 - 0.028 13.8 0.0 13 5.0 0.0 3.4 2 1 0 3 3 3 0 WD40-like domain AAA_7 PF12775.7 KIK56870.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIK56870.1 - 0.045 13.1 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 KaiC PhoH PF02562.16 KIK56870.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF4422 PF14393.6 KIK56870.1 - 0.22 11.4 2.3 0.43 10.4 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Proteasome_A_N PF10584.9 KIK56870.1 - 0.74 9.6 5.0 37 4.1 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature CFTR_R PF14396.6 KIK56873.1 - 0.11 12.0 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain MFS_1 PF07690.16 KIK56875.1 - 0.015 14.2 6.0 0.023 13.7 6.0 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily adh_short PF00106.25 KIK56877.1 - 8.2e-38 129.8 0.0 1.1e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56877.1 - 6.9e-31 107.6 0.0 9.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK56877.1 - 3.4e-06 27.1 0.4 6.3e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KIK56877.1 - 0.0026 17.1 0.1 0.0051 16.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KIK56877.1 - 0.016 14.7 0.2 0.036 13.5 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIK56877.1 - 0.028 13.7 0.1 0.061 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KIK56877.1 - 0.032 14.3 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KIK56877.1 - 0.045 13.6 0.3 0.064 13.1 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KIK56877.1 - 0.071 13.2 1.0 0.13 12.3 1.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.19 KIK56877.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ThiF PF00899.21 KIK56877.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family Methyltransf_25 PF13649.6 KIK56877.1 - 0.13 12.9 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 KIK56878.1 - 1.1e-36 126.1 0.2 1.5e-36 125.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56878.1 - 2.5e-31 109.1 0.0 3.1e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK56878.1 - 2.6e-06 27.5 0.9 5.1e-06 26.5 0.9 1.4 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KIK56878.1 - 1.6e-05 24.3 0.1 5.4e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 KIK56878.1 - 0.0036 16.8 0.3 0.0049 16.3 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 KIK56878.1 - 0.004 16.5 0.1 0.0077 15.6 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 KIK56878.1 - 0.005 16.9 1.2 0.0083 16.2 1.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KIK56878.1 - 0.014 15.3 0.5 0.019 14.9 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pantoate_transf PF02548.15 KIK56878.1 - 0.035 13.5 0.8 0.053 12.9 0.8 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Epimerase PF01370.21 KIK56878.1 - 0.038 13.5 0.2 0.1 12.1 0.2 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIK56878.1 - 0.061 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIK56878.1 - 0.08 12.5 0.6 0.11 12.0 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SopA_C PF13979.6 KIK56878.1 - 0.082 12.6 0.0 15 5.3 0.0 2.3 1 1 1 2 2 2 0 SopA-like catalytic domain ADH_zinc_N PF00107.26 KIK56878.1 - 0.16 12.0 1.0 0.27 11.2 1.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cu-oxidase PF00394.22 KIK56879.1 - 1.3e-45 155.4 0.0 5.4e-44 150.1 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK56879.1 - 3.1e-37 127.4 0.2 1.3e-34 118.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK56879.1 - 6.2e-28 97.2 0.6 3.7e-26 91.5 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase adh_short PF00106.25 KIK56880.1 - 3.2e-35 121.4 0.2 4.5e-35 120.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK56880.1 - 1.6e-26 93.3 0.0 2.3e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK56880.1 - 1.2e-08 35.1 2.1 1.4e-08 34.9 0.8 1.7 2 0 0 2 2 2 1 KR domain Oxidored_nitro PF00148.19 KIK56880.1 - 0.00022 20.1 0.1 0.0003 19.6 0.1 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.19 KIK56880.1 - 0.0023 17.3 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KIK56880.1 - 0.018 14.4 0.6 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KIK56880.1 - 0.025 14.0 0.2 0.11 11.9 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIK56880.1 - 0.21 11.5 0.5 0.31 10.9 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KIK56880.1 - 0.25 11.4 4.9 1.1 9.2 4.9 1.9 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DEAD PF00270.29 KIK56881.1 - 6.5e-37 127.0 0.0 3.2e-35 121.5 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK56881.1 - 7.8e-28 97.0 0.0 2.4e-26 92.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK56881.1 - 6.7e-05 23.0 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cu-oxidase PF00394.22 KIK56882.1 - 4e-45 153.8 0.2 2.7e-43 147.8 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK56882.1 - 1.6e-38 131.5 4.0 1.4e-36 125.3 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK56882.1 - 1e-34 119.1 2.2 2e-32 111.7 0.1 3.9 5 0 0 5 5 5 1 Multicopper oxidase Epimerase PF01370.21 KIK56883.1 - 3.7e-17 62.6 0.0 1.6e-16 60.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK56883.1 - 1e-11 44.4 0.0 3.7e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK56883.1 - 2.9e-07 30.2 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK56883.1 - 2.6e-06 27.5 0.0 8.9e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK56883.1 - 4.6e-06 26.0 0.0 0.016 14.4 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KIK56883.1 - 0.00043 19.5 0.0 0.00092 18.4 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIK56883.1 - 0.004 16.3 0.0 0.0076 15.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK56883.1 - 0.0041 16.7 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK56883.1 - 0.0087 15.5 0.0 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK56883.1 - 0.48 10.3 1.5 3.1 7.7 0.8 2.3 2 1 0 2 2 2 0 KR domain adh_short_C2 PF13561.6 KIK56884.1 - 7e-50 169.8 0.6 9.6e-50 169.3 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK56884.1 - 1.6e-41 141.9 0.7 2.8e-41 141.2 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK56884.1 - 3.2e-18 66.3 0.7 4e-18 65.9 0.7 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KIK56884.1 - 4.8e-06 25.8 0.1 6.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK56884.1 - 2.3e-05 24.0 0.1 6.6e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK56884.1 - 5e-05 22.9 0.3 9.9e-05 21.9 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIK56884.1 - 7.2e-05 22.1 0.1 0.0001 21.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.21 KIK56884.1 - 0.0062 16.3 0.1 0.0092 15.7 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Stevor PF17410.2 KIK56886.1 - 0.0035 16.9 0.5 0.0047 16.5 0.5 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 KIK56886.1 - 0.19 12.6 0.0 0.25 12.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Wzy_C PF04932.15 KIK56887.1 - 0.2 11.3 1.0 0.3 10.7 1.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Syndecan PF01034.20 KIK56888.1 - 0.055 13.4 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain RPW8 PF05659.11 KIK56888.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Gram_pos_anchor PF00746.21 KIK56888.1 - 8.3 6.5 6.4 0.69 9.9 1.2 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 KIK56889.1 - 7.1 6.7 7.3 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 Podoplanin F-box-like PF12937.7 KIK56893.1 - 7.4e-06 25.8 1.8 1e-05 25.3 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK56893.1 - 0.034 14.0 1.9 4.3 7.3 0.1 3.8 3 0 0 3 3 3 0 F-box domain PP2C PF00481.21 KIK56894.1 - 1.7e-21 77.0 0.0 2.1e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KIK56894.1 - 0.0043 16.7 0.1 0.056 13.1 0.1 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C GMC_oxred_N PF00732.19 KIK56895.1 - 1.9e-61 208.1 0.2 2.4e-61 207.7 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK56895.1 - 2.8e-31 109.0 0.0 5e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK56895.1 - 0.0036 16.4 0.2 0.0068 15.5 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HHH_5 PF14520.6 KIK56895.1 - 0.013 16.1 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 KIK56895.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DIOX_N PF14226.6 KIK56896.1 - 8.8e-26 91.0 0.0 1.5e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK56896.1 - 1.3e-17 64.1 0.0 2.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK56897.1 - 8.4e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK56897.1 - 2.3e-18 66.5 0.0 4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AP_endonuc_2 PF01261.24 KIK56898.1 - 1.2e-37 129.4 0.0 2.1e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GspL_C PF12693.7 KIK56899.1 - 0.2 11.5 3.3 0.19 11.6 1.4 1.8 2 0 0 2 2 2 0 GspL periplasmic domain GMC_oxred_N PF00732.19 KIK56901.1 - 3.6e-16 59.4 0.1 1.4e-15 57.5 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DUF1688 PF07958.11 KIK56901.1 - 0.083 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) GFO_IDH_MocA PF01408.22 KIK56902.1 - 1.2e-20 74.6 0.0 1.9e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK56902.1 - 0.00014 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DXP_reductoisom PF02670.16 KIK56902.1 - 0.033 14.9 0.0 0.061 14.0 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KIK56902.1 - 0.08 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KIK56903.1 - 6.3e-66 222.7 0.0 8.2e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK56903.1 - 1.4e-31 109.9 0.0 2.6e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK56903.1 - 0.005 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ARD PF03079.14 KIK56904.1 - 2.5e-11 44.0 0.0 3.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIK56904.1 - 0.00045 19.9 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain WD40 PF00400.32 KIK56907.1 - 1.2e-90 295.0 50.3 2.5e-09 37.6 0.1 13.0 12 1 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56907.1 - 3.2e-35 120.3 0.2 0.027 14.7 0.0 11.1 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56907.1 - 7.9e-25 86.2 1.8 1.9 8.5 0.0 12.3 12 0 0 12 12 12 5 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK56907.1 - 5.3e-13 49.3 0.0 0.0088 15.9 0.0 5.0 2 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK56907.1 - 1.9e-11 43.0 0.0 0.35 9.1 0.0 7.2 5 2 0 7 7 7 4 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK56907.1 - 2e-09 36.9 4.1 4.2 6.2 0.0 8.5 4 3 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK56907.1 - 3.9e-09 36.3 0.2 1.3 8.3 0.0 6.6 5 2 2 7 7 7 3 WD40-like domain NACHT PF05729.12 KIK56907.1 - 7.4e-08 32.5 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK56907.1 - 4.5e-07 30.3 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK56907.1 - 1.1e-05 25.9 0.0 2.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DPPIV_N PF00930.21 KIK56907.1 - 0.00091 18.1 0.1 8.9 5.0 0.0 5.7 6 1 0 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_7 PF12775.7 KIK56907.1 - 0.0092 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PIF1 PF05970.14 KIK56907.1 - 0.045 12.9 0.1 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 KIK56907.1 - 0.067 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Proteasome_A_N PF10584.9 KIK56907.1 - 0.086 12.5 18.9 1.2e+02 2.5 0.0 10.0 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KIK56907.1 - 0.094 11.3 0.0 8.1 4.9 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 ATPase_2 PF01637.18 KIK56907.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1769 PF08588.10 KIK56908.1 - 1.2e-21 76.7 0.5 2.2e-21 75.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Apt1 PF10351.9 KIK56908.1 - 2.4 6.9 8.0 2.8 6.7 8.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_1 PF07690.16 KIK56909.1 - 3.4e-30 105.2 22.8 4.2e-30 104.9 20.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M66 PF10462.9 KIK56910.1 - 0.038 13.0 0.2 0.31 9.9 0.1 2.0 2 0 0 2 2 2 0 Peptidase M66 DUF1624 PF07786.12 KIK56911.1 - 0.19 11.2 8.2 0.028 14.0 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) Asp_protease_2 PF13650.6 KIK56912.1 - 0.00032 21.3 0.1 0.019 15.6 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK56912.1 - 0.03 14.9 0.1 0.52 10.9 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sacchrp_dh_NADP PF03435.18 KIK56914.1 - 0.0034 17.6 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIK56914.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KIK56914.1 - 0.084 12.3 0.0 0.53 9.7 0.1 2.2 2 1 0 2 2 2 0 short chain dehydrogenase AAA_16 PF13191.6 KIK56915.1 - 2.1e-06 28.2 0.0 2.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.17 KIK56915.1 - 0.0013 17.9 0.1 0.0021 17.2 0.1 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 KIK56915.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 KIK56915.1 - 0.0018 18.2 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 KIK56915.1 - 0.0022 17.6 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KIK56915.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KIK56915.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Torsin PF06309.11 KIK56915.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Torsin DUF815 PF05673.13 KIK56915.1 - 0.05 12.8 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK56915.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KIK56915.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.6 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.22 KIK56915.1 - 0.17 11.0 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 KIK56915.1 - 0.18 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 KIK56915.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK56915.1 - 0.24 10.6 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 KIK56916.1 - 3.6e-145 467.5 76.9 3e-10 40.5 0.9 15.8 15 1 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56916.1 - 1.3e-60 201.7 10.9 0.003 17.8 0.0 14.2 1 1 13 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56916.1 - 9e-29 98.8 9.1 2.3 8.3 0.0 14.5 14 0 0 14 14 14 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56916.1 - 8.7e-23 80.8 0.2 0.13 11.2 0.0 13.0 1 1 13 14 14 14 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK56916.1 - 7.6e-09 35.3 0.0 2.8 7.2 0.0 8.2 7 3 3 10 10 10 3 WD40-like domain Frtz PF11768.8 KIK56916.1 - 1.8e-08 33.2 0.0 6.6 4.9 0.0 8.9 8 4 3 11 11 11 1 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK56916.1 - 3e-06 26.8 31.4 6 6.6 0.2 12.8 13 0 0 13 13 13 1 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KIK56916.1 - 1.3e-05 25.5 3.8 68 4.1 0.0 8.2 7 3 3 10 10 10 0 PQQ-like domain PQQ PF01011.21 KIK56916.1 - 5.9e-05 22.8 0.0 59 3.8 0.0 7.7 9 0 0 9 9 8 0 PQQ enzyme repeat Nup160 PF11715.8 KIK56916.1 - 9.9e-05 21.2 3.9 1.2 7.6 0.0 6.4 8 2 2 10 10 10 2 Nucleoporin Nup120/160 Cuticle_4 PF15955.5 KIK56916.1 - 0.008 16.9 0.3 2e+02 2.8 0.0 6.4 9 0 0 9 9 8 0 Cuticle protein FCP1_C PF09309.10 KIK56916.1 - 0.0091 15.9 0.0 77 3.0 0.0 5.4 5 1 0 6 6 6 0 FCP1, C-terminal UN_NPL4 PF11543.8 KIK56916.1 - 0.024 15.1 0.3 78 3.9 0.0 6.4 9 1 1 10 10 7 0 Nuclear pore localisation protein NPL4 Emaravirus_P4 PF16505.5 KIK56916.1 - 0.037 13.1 0.0 8.3 5.3 0.0 3.9 4 1 0 5 5 5 0 P4 movement protein of Emaravirus, and the 30K superfamily Pyr_redox_dim PF02852.22 KIK56916.1 - 0.051 13.8 0.0 1.1e+02 3.1 0.0 5.2 5 1 2 7 7 7 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PH_9 PF15410.6 KIK56918.1 - 9.2e-05 22.8 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK56918.1 - 0.0025 18.3 0.0 0.0031 18.0 0.0 1.1 1 0 0 1 1 1 1 PH domain DUF1110 PF06533.12 KIK56918.1 - 0.058 13.3 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Metallophos PF00149.28 KIK56919.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK56919.1 - 9.9e-22 77.1 0.5 2.1e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DAO PF01266.24 KIK56920.1 - 3.1e-30 106.0 0.9 3.8e-30 105.7 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK56920.1 - 0.0043 17.6 2.9 0.061 13.9 0.9 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK56920.1 - 0.013 14.8 0.0 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.6 KIK56921.1 - 3e-09 36.7 0.2 8.1e-09 35.4 0.2 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase Caf4 PF11615.8 KIK56921.1 - 0.061 13.3 0.1 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 CCR4-associated factor 4 p450 PF00067.22 KIK56922.1 - 4.4e-66 223.5 0.0 1.4e-65 221.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF655 PF04919.12 KIK56922.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Cyclase PF04199.13 KIK56923.1 - 9.9e-35 119.7 0.2 1.8e-34 118.9 0.2 1.4 2 0 0 2 2 2 1 Putative cyclase Cyclase PF04199.13 KIK56924.1 - 1.2e-30 106.5 0.4 1.7e-30 106.0 0.4 1.2 1 0 0 1 1 1 1 Putative cyclase Methyltransf_2 PF00891.18 KIK56925.1 - 1.7e-15 56.9 0.0 3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 KIK56925.1 - 0.0054 17.1 0.1 0.64 10.4 0.0 2.7 3 0 0 3 3 3 1 Transcriptional regulator MTS PF05175.14 KIK56925.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain XFP PF03894.15 KIK56925.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase RNA_pol_Rpc34 PF05158.12 KIK56925.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit WD40 PF00400.32 KIK56926.1 - 3.2e-118 382.2 82.2 6.3e-09 36.3 0.9 15.6 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56926.1 - 5.4e-53 177.3 2.2 0.0067 16.7 0.0 14.2 1 1 13 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56926.1 - 7.4e-21 73.6 23.5 0.19 11.7 0.1 14.0 14 0 0 14 14 14 6 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK56926.1 - 2.7e-16 59.0 0.0 0.16 10.3 0.0 8.9 2 2 8 10 10 10 6 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK56926.1 - 1.3e-11 44.1 8.7 3.3 6.6 0.0 10.5 3 3 10 14 14 14 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK56926.1 - 2.4e-09 36.9 0.0 1.2 8.4 0.0 7.1 6 1 2 8 8 8 2 WD40-like domain AAA_16 PF13191.6 KIK56926.1 - 7.3e-08 33.0 0.0 1.8e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KIK56926.1 - 1.4e-07 30.4 0.3 0.09 11.3 0.0 4.8 3 2 0 5 5 5 2 Cytochrome D1 heme domain NACHT PF05729.12 KIK56926.1 - 1.9e-07 31.1 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK56926.1 - 1.6e-05 25.3 0.0 5.2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KIK56926.1 - 0.0026 17.0 0.1 2.8 7.1 0.0 2.5 2 1 0 3 3 3 2 KAP family P-loop domain AAA_7 PF12775.7 KIK56926.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Proteasome_A_N PF10584.9 KIK56926.1 - 0.014 15.1 22.3 59 3.5 0.1 11.1 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature PIF1 PF05970.14 KIK56926.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 KIK56926.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DPPIV_N PF00930.21 KIK56926.1 - 0.22 10.2 1.6 11 4.6 0.0 4.8 5 1 0 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UPF0220 PF05255.11 KIK56927.1 - 3.2e-53 179.7 0.1 3.8e-53 179.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Zn_clus PF00172.18 KIK56929.1 - 1.4e-08 34.7 9.1 2.4e-08 33.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK56929.1 - 0.037 13.1 0.9 0.28 10.2 0.8 2.2 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF2106 PF09879.9 KIK56929.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Glyco_hydro_43 PF04616.14 KIK56930.1 - 1.6e-40 139.3 0.7 1.9e-40 139.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 KIK56931.1 - 1.4e-40 139.4 0.4 1.6e-40 139.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Smg8_Smg9 PF10220.9 KIK56931.1 - 0.17 10.2 0.2 0.22 9.8 0.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 TRI5 PF06330.11 KIK56932.1 - 2.7e-16 59.4 0.0 3.4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DIOX_N PF14226.6 KIK56933.1 - 1.1e-25 90.7 0.0 1.9e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK56933.1 - 3.2e-17 62.9 0.0 6.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amino_oxidase PF01593.24 KIK56935.1 - 6.6e-60 203.7 0.2 7.4e-59 200.2 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK56935.1 - 1.2e-15 57.5 0.3 3e-15 56.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK56935.1 - 7.5e-10 38.9 0.2 3.9e-08 33.3 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK56935.1 - 2e-07 30.4 0.2 3e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK56935.1 - 3.2e-07 30.0 0.5 5.6e-07 29.3 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK56935.1 - 9e-07 28.4 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KIK56935.1 - 1e-05 26.0 0.2 4.3e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK56935.1 - 3.1e-05 23.4 0.0 0.00015 21.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK56935.1 - 5.9e-05 22.0 0.4 0.00038 19.3 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KIK56935.1 - 9.5e-05 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIK56935.1 - 0.00053 19.1 0.0 0.0087 15.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein MCRA PF06100.11 KIK56935.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 MCRA family GIDA PF01134.22 KIK56935.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIK56935.1 - 0.0029 16.9 0.1 0.017 14.4 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK56935.1 - 0.0065 16.5 0.3 0.079 12.9 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK56935.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KIK56935.1 - 0.4 9.5 1.1 0.49 9.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 KIK56936.1 - 1.3e-31 109.8 27.2 1.3e-31 109.8 27.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK56936.1 - 9.6e-10 37.9 6.9 9.6e-10 37.9 6.9 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIK56936.1 - 3.3e-06 25.8 2.7 5.1e-06 25.2 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KIK56938.1 - 2.1e-31 109.1 26.7 2.5e-31 108.9 26.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK56938.1 - 9.5e-12 44.5 7.7 9.5e-12 44.5 7.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK56938.1 - 1.2e-05 24.0 2.6 1.9e-05 23.3 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KIK56939.1 - 3e-47 161.4 0.0 4.5e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KIK56940.1 - 1.4e-47 162.3 0.0 1.2e-46 159.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Catalase PF00199.19 KIK56940.1 - 0.07 12.2 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Catalase FtsH_ext PF06480.15 KIK56940.1 - 0.12 12.7 0.1 0.66 10.4 0.0 2.0 2 0 0 2 2 2 0 FtsH Extracellular Spore_III_AE PF09546.10 KIK56941.1 - 0.025 13.8 0.4 0.035 13.3 0.4 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) p450 PF00067.22 KIK56942.1 - 3.1e-66 224.0 0.0 4.3e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIK56943.1 - 1.3e-34 119.7 49.8 2.3e-33 115.6 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK56943.1 - 7.3e-07 28.8 2.5 7.3e-07 28.8 2.5 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB NodZ PF05830.11 KIK56943.1 - 0.037 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) OAD_gamma PF04277.13 KIK56943.1 - 0.056 14.0 2.2 7.1 7.3 0.0 3.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3624 PF12292.8 KIK56943.1 - 2.1 8.8 8.0 0.67 10.4 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) FAD_binding_4 PF01565.23 KIK56944.1 - 5.9e-16 58.5 0.0 9.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK56944.1 - 6.7e-09 35.7 1.0 2.4e-08 34.0 0.3 2.2 2 0 0 2 2 2 1 Berberine and berberine like BChl_A PF02327.17 KIK56944.1 - 0.025 13.4 0.0 0.049 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriochlorophyll A protein Cytokin-bind PF09265.10 KIK56944.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding 2-oxogl_dehyd_N PF16078.5 KIK56944.1 - 0.31 10.7 0.1 0.31 10.7 0.1 2.3 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus peroxidase PF00141.23 KIK56945.1 - 8e-22 78.1 0.0 1.4e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 KIK56946.1 - 3.5e-21 75.9 0.0 6.4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Asp PF00026.23 KIK56947.1 - 2.1e-14 53.7 2.1 3.2e-06 26.8 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIK56947.1 - 1.8e-06 28.5 0.4 0.0042 17.7 0.1 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK56947.1 - 0.00049 20.6 0.1 0.049 14.2 0.1 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease peroxidase PF00141.23 KIK56949.1 - 1.3e-12 47.9 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 KIK56950.1 - 1.5e-21 77.1 0.0 2.7e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Av_adeno_fibre PF06536.11 KIK56950.1 - 0.21 11.4 0.9 15 5.5 0.5 2.7 2 0 0 2 2 2 0 Avian adenovirus fibre, N-terminal WD40 PF00400.32 KIK56951.1 - 5e-108 350.0 68.4 3e-09 37.3 0.4 14.0 14 0 0 14 14 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56951.1 - 1.3e-44 150.4 0.9 0.016 15.5 0.0 12.3 1 1 12 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56951.1 - 9.5e-24 82.8 7.5 0.8 9.7 0.0 12.4 12 0 0 12 12 12 6 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56951.1 - 1.9e-13 50.1 10.3 0.94 8.4 0.0 11.2 1 1 9 12 12 12 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK56951.1 - 3e-07 30.5 0.0 5.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CHAP PF05257.16 KIK56951.1 - 1.5e-06 28.7 20.4 24 5.6 0.1 10.4 2 2 8 10 10 10 0 CHAP domain AAA PF00004.29 KIK56951.1 - 6.8e-06 26.5 0.0 3.6e-05 24.2 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK56951.1 - 1.3e-05 25.7 0.0 5.5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PQQ PF01011.21 KIK56951.1 - 0.0002 21.1 0.0 44 4.2 0.0 7.2 8 1 0 8 8 8 0 PQQ enzyme repeat PIF1 PF05970.14 KIK56951.1 - 0.00086 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase WD40_like PF17005.5 KIK56951.1 - 0.0015 17.9 0.2 3.3 7.0 0.0 4.2 6 1 0 7 7 7 1 WD40-like domain AAA_7 PF12775.7 KIK56951.1 - 0.003 17.1 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF1513 PF07433.11 KIK56951.1 - 0.0044 16.1 9.6 14 4.7 0.2 7.6 1 1 6 9 9 9 0 Protein of unknown function (DUF1513) YmaF PF12788.7 KIK56951.1 - 0.1 13.1 3.5 4.3e+02 1.5 0.0 6.7 6 3 2 8 8 8 0 YmaF family KAP_NTPase PF07693.14 KIK56951.1 - 0.15 11.2 0.3 6.5 5.9 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 KIK56951.1 - 0.16 11.1 0.0 0.44 9.7 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Proteasome_A_N PF10584.9 KIK56951.1 - 0.33 10.7 22.3 15 5.3 0.1 8.7 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature FAD_binding_4 PF01565.23 KIK56952.1 - 1.9e-15 56.8 0.0 3.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK56952.1 - 4.1e-08 33.2 1.1 1.3e-07 31.5 0.3 2.2 2 0 0 2 2 2 1 Berberine and berberine like DUF4476 PF14771.6 KIK56952.1 - 0.094 13.0 0.9 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) p450 PF00067.22 KIK56953.1 - 7.4e-69 232.7 0.0 9.5e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK56955.1 - 9.7e-49 162.3 29.0 3.2e-10 40.4 0.1 8.0 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56955.1 - 8e-19 67.7 0.4 0.011 16.0 0.0 6.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK56955.1 - 1.5e-09 38.0 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK56955.1 - 2.9e-07 31.0 0.0 7.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KIK56955.1 - 7.1e-07 29.0 1.8 0.75 9.8 0.0 5.3 5 1 1 6 6 6 3 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK56955.1 - 8.3e-07 29.5 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 KIK56955.1 - 0.0084 16.2 0.0 0.041 14.0 0.0 2.1 2 0 0 2 2 2 1 Torsin IstB_IS21 PF01695.17 KIK56955.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KIK56955.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 KIK56955.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 KIK56955.1 - 0.086 13.1 0.1 0.47 10.7 0.0 2.3 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIK56955.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Proteasome_A_N PF10584.9 KIK56955.1 - 0.12 12.1 5.5 51 3.7 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PhoH PF02562.16 KIK56955.1 - 0.19 11.2 0.1 0.52 9.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein TNFR_c6 PF00020.18 KIK56956.1 - 0.027 14.9 0.5 0.027 14.9 0.5 3.0 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region Helitron_like_N PF14214.6 KIK56957.1 - 2.6e-26 93.0 0.0 2.8e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.14 KIK56960.1 - 0.006 14.6 0.0 0.006 14.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KIK56960.1 - 0.038 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF5588 PF17826.1 KIK56960.1 - 0.15 10.9 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5588) NACHT PF05729.12 KIK56963.1 - 3.7e-06 27.0 0.0 4.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK56963.1 - 4.9e-06 27.0 0.0 7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK56963.1 - 2.2e-05 24.9 0.0 3.8e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK56963.1 - 0.0028 17.2 0.0 0.0085 15.6 0.0 1.8 2 1 1 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK56963.1 - 0.0069 16.1 0.1 0.015 15.1 0.1 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.9 KIK56963.1 - 0.0075 15.5 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK56963.1 - 0.01 16.1 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK56963.1 - 0.022 15.1 0.1 0.034 14.5 0.1 1.7 1 1 0 1 1 1 0 RNA helicase PhoH PF02562.16 KIK56963.1 - 0.024 14.1 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KIK56963.1 - 0.027 14.2 0.0 0.027 14.2 0.0 1.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK56963.1 - 0.053 12.7 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KIK56963.1 - 0.057 13.3 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KIK56963.1 - 0.066 12.9 0.1 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Cytidylate kinase Glyco_hydro_129 PF11308.8 KIK56963.1 - 0.088 12.0 0.0 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 AAA_PrkA PF08298.11 KIK56963.1 - 0.091 11.7 0.0 0.12 11.2 0.0 1.3 1 1 0 1 1 1 0 PrkA AAA domain AAA_18 PF13238.6 KIK56963.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KIK56963.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KIK56963.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK56963.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.8 1 1 0 1 1 1 0 NTPase PIF1 PF05970.14 KIK56963.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_5 PF07728.14 KIK56963.1 - 0.21 11.6 0.0 0.62 10.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 KIK56964.1 - 4.8e-74 242.4 34.9 1.2e-10 41.8 0.1 8.0 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56964.1 - 7.2e-34 116.0 0.4 0.00067 19.9 0.0 7.5 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56964.1 - 7.3e-20 70.4 1.7 0.57 10.2 0.0 8.3 8 0 0 8 8 8 6 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56964.1 - 1e-11 44.4 0.6 1.7 7.6 0.0 7.5 3 2 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK56964.1 - 3.8e-07 29.7 11.7 1.4 8.6 0.1 6.5 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature eIF2A PF08662.11 KIK56964.1 - 2.9e-06 27.3 0.0 0.15 11.9 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KIK56964.1 - 9.4e-05 22.2 0.1 38 4.4 0.0 5.6 6 0 0 6 6 6 0 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK56964.1 - 0.00048 19.0 0.1 1.2 7.9 0.0 4.2 2 2 4 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nucleoporin_N PF08801.11 KIK56964.1 - 0.0033 16.2 0.8 0.43 9.3 0.1 3.5 1 1 0 2 2 2 1 Nup133 N terminal like Pyr_redox_dim PF02852.22 KIK56964.1 - 0.0085 16.3 0.0 77 3.6 0.0 4.3 2 2 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain WD40_like PF17005.5 KIK56964.1 - 0.013 14.9 0.0 31 3.7 0.0 4.2 3 2 2 5 5 5 0 WD40-like domain PQQ_3 PF13570.6 KIK56964.1 - 0.013 15.9 2.4 30 5.3 0.0 4.7 3 2 3 6 6 5 0 PQQ-like domain Frtz PF11768.8 KIK56964.1 - 0.026 12.9 0.0 14 3.8 0.0 4.1 4 2 0 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK56964.1 - 0.067 12.5 2.3 17 4.7 0.0 3.9 3 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK56964.1 - 0.15 10.7 0.2 35 2.9 0.0 3.8 4 1 1 5 5 5 0 Nucleoporin Nup120/160 DUF3222 PF11519.8 KIK56964.1 - 0.31 11.3 1.4 4 7.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3222) Cuticle_4 PF15955.5 KIK56964.1 - 0.51 11.1 2.0 4.5e+02 1.6 0.0 4.6 6 0 0 6 6 5 0 Cuticle protein DUF4402 PF14352.6 KIK56964.1 - 0.84 10.3 2.7 34 5.1 0.1 3.9 2 2 1 4 4 4 0 Domain of unknown function (DUF4402) p450 PF00067.22 KIK56965.1 - 1e-17 64.0 0.0 1.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PRAI PF00697.22 KIK56965.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase WD40 PF00400.32 KIK56968.1 - 3e-110 357.0 41.6 8.8e-11 42.2 0.2 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56968.1 - 4.6e-45 151.8 3.8 0.00072 19.8 0.0 11.0 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56968.1 - 8.6e-20 70.2 10.4 0.065 13.2 0.1 9.7 10 0 0 10 10 10 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56968.1 - 4.2e-13 49.0 0.2 0.65 8.9 0.0 9.0 1 1 8 10 10 10 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK56968.1 - 2.2e-12 47.3 0.0 0.0013 18.7 0.0 4.5 2 1 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK56968.1 - 2e-10 39.8 0.2 0.022 13.3 0.0 4.2 1 1 2 4 4 4 3 Cytochrome D1 heme domain Frtz PF11768.8 KIK56968.1 - 2.2e-09 36.2 0.0 1.2 7.4 0.0 7.6 6 2 1 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK56968.1 - 2.8e-08 34.0 2.3 31 5.2 0.0 8.4 5 2 5 10 10 10 0 PQQ-like domain WD40_like PF17005.5 KIK56968.1 - 3.6e-08 33.1 0.0 1 8.6 0.0 6.5 8 1 0 8 8 8 2 WD40-like domain Proteasome_A_N PF10584.9 KIK56968.1 - 1.7e-07 30.8 16.0 25 4.7 0.0 8.6 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature BBS2_Mid PF14783.6 KIK56968.1 - 1.3e-05 25.1 0.1 51 4.0 0.0 7.5 9 1 0 9 9 9 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 KIK56968.1 - 2.1e-05 24.2 7.4 0.25 10.9 0.3 4.8 1 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 KIK56968.1 - 0.00013 21.7 3.4 40 4.4 0.0 7.3 9 0 0 9 9 9 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIK56968.1 - 0.00022 20.2 0.0 1.5 7.6 0.0 4.4 3 2 1 5 5 5 2 Methylamine dehydrogenase heavy chain (MADH) Peptidase_S9_N PF02897.15 KIK56968.1 - 0.00031 19.7 0.1 28 3.4 0.0 5.8 3 2 5 8 8 8 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Nucleoporin_N PF08801.11 KIK56968.1 - 0.00033 19.5 1.7 5.6 5.6 0.1 5.6 2 2 0 4 4 4 1 Nup133 N terminal like Pyr_redox_dim PF02852.22 KIK56968.1 - 0.00041 20.6 0.0 21 5.4 0.0 5.1 5 2 2 7 7 6 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Nup160 PF11715.8 KIK56968.1 - 0.00056 18.7 0.3 7.9 5.0 0.0 4.8 6 0 0 6 6 6 1 Nucleoporin Nup120/160 CHASE9 PF17153.4 KIK56968.1 - 0.014 15.5 0.0 20 5.3 0.0 3.4 3 0 0 3 3 3 0 Periplasmic sensor domain, extracellular Cuticle_4 PF15955.5 KIK56968.1 - 1.5 9.6 4.9 39 5.0 0.0 4.9 6 0 0 6 6 4 0 Cuticle protein AAA_16 PF13191.6 KIK56969.1 - 8.4e-08 32.8 0.0 1.4e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK56969.1 - 1.5e-05 25.0 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK56969.1 - 0.0001 22.8 0.0 0.0002 21.8 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK56969.1 - 0.00053 19.5 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region Torsin PF06309.11 KIK56969.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Torsin PIF1 PF05970.14 KIK56969.1 - 0.0017 17.6 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ATPase_2 PF01637.18 KIK56969.1 - 0.0022 17.9 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KIK56969.1 - 0.0023 17.7 0.1 0.0044 16.8 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KIK56969.1 - 0.0031 17.0 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein NB-ARC PF00931.22 KIK56969.1 - 0.0051 16.0 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KIK56969.1 - 0.0063 15.8 0.0 0.0063 15.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK56969.1 - 0.0076 16.5 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK56969.1 - 0.014 16.0 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK56969.1 - 0.019 14.2 0.1 0.84 8.8 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 KIK56969.1 - 0.024 14.8 0.0 0.034 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_35 PF14516.6 KIK56969.1 - 0.029 13.2 0.0 0.033 13.0 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 KIK56969.1 - 0.035 13.8 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK56969.1 - 0.046 14.1 0.1 0.069 13.6 0.1 1.7 1 1 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KIK56969.1 - 0.048 12.9 0.0 0.096 12.0 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 KIK56969.1 - 0.069 12.9 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Parvo_NS1 PF01057.17 KIK56969.1 - 0.081 12.0 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KIK56969.1 - 0.089 12.0 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 KIK56969.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_PrkA PF08298.11 KIK56969.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain NTPase_1 PF03266.15 KIK56969.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 NTPase NACHT PF05729.12 KIK56975.1 - 2.1e-09 37.5 0.0 6.5e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK56975.1 - 2.4e-08 34.5 0.0 3e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK56975.1 - 1.1e-07 32.4 0.0 9e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK56975.1 - 0.0015 18.1 0.0 0.0061 16.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Torsin PF06309.11 KIK56975.1 - 0.0053 16.9 0.1 0.025 14.7 0.0 2.2 3 0 0 3 3 3 1 Torsin IstB_IS21 PF01695.17 KIK56975.1 - 0.0075 16.0 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 KIK56975.1 - 0.011 16.0 0.0 0.05 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KIK56975.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KIK56975.1 - 0.015 14.5 1.0 0.091 11.9 0.0 2.5 3 1 0 3 3 3 0 NB-ARC domain PhoH PF02562.16 KIK56975.1 - 0.039 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF4393 PF14337.6 KIK56975.1 - 0.04 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) KAP_NTPase PF07693.14 KIK56975.1 - 0.064 12.5 0.1 1.7 7.8 0.0 2.6 2 1 0 3 3 3 0 KAP family P-loop domain Parvo_NS1 PF01057.17 KIK56975.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KIK56975.1 - 0.095 11.9 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 KIK56975.1 - 0.1 12.3 0.1 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase DUF1338 PF07063.13 KIK56975.1 - 0.15 11.3 0.1 0.76 8.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) WD40 PF00400.32 KIK56976.1 - 3.4e-96 312.5 58.0 1.4e-10 41.6 0.4 13.5 11 2 1 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK56976.1 - 4.1e-42 142.4 0.1 0.0014 18.9 0.0 10.6 1 1 10 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK56976.1 - 1.4e-23 82.2 9.2 0.28 11.2 0.0 10.6 10 0 0 10 10 10 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK56976.1 - 5e-12 45.4 0.0 2.2 7.2 0.0 8.0 3 2 4 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK56976.1 - 2.5e-10 39.8 21.7 4.1 7.2 0.2 10.0 10 0 0 10 10 10 3 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KIK56976.1 - 3.5e-08 32.4 0.0 0.67 8.4 0.0 4.7 1 1 4 6 6 6 4 Cytochrome D1 heme domain PQQ PF01011.21 KIK56976.1 - 3.7e-06 26.6 0.0 1.6e+02 2.4 0.0 8.6 10 0 0 10 10 10 0 PQQ enzyme repeat Pyr_redox_dim PF02852.22 KIK56976.1 - 5.4e-06 26.6 0.0 31 4.9 0.0 6.7 4 3 4 8 8 8 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Nucleoporin_N PF08801.11 KIK56976.1 - 6.4e-06 25.2 0.1 1.5 7.5 0.0 5.5 2 1 2 5 5 5 2 Nup133 N terminal like PQQ_3 PF13570.6 KIK56976.1 - 2.4e-05 24.7 0.6 48 4.6 0.0 6.9 6 2 2 8 8 8 0 PQQ-like domain Peptidase_S9_N PF02897.15 KIK56976.1 - 0.00094 18.1 0.6 35 3.0 0.0 5.8 2 2 2 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK56976.1 - 0.0011 17.4 0.0 21 3.3 0.0 5.3 6 1 0 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz nos_propeller PF18764.1 KIK56976.1 - 0.0043 16.9 0.6 23 5.0 0.0 5.2 6 0 0 6 6 6 0 Nitrous oxide reductase propeller repeat DUF5122 PF17164.4 KIK56976.1 - 0.014 15.7 6.7 3.8 7.9 0.0 6.6 9 1 0 9 9 8 0 Domain of unknown function (DUF5122) beta-propeller Adeno_E3_15_3 PF03307.14 KIK56976.1 - 0.07 13.1 0.0 45 4.0 0.0 3.9 5 0 0 5 5 5 0 Adenovirus 15.3kD protein in E3 region Tannase PF07519.11 KIK56977.1 - 5.9e-117 391.4 0.0 6.9e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KIK56977.1 - 0.068 12.4 0.0 0.71 9.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Tannase PF07519.11 KIK56978.1 - 3.5e-110 369.1 0.0 4.1e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Dynamin_M PF01031.20 KIK56979.1 - 8.1e-108 360.0 0.0 1.3e-107 359.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK56979.1 - 5.2e-56 189.3 0.0 9.1e-56 188.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK56979.1 - 5e-29 100.3 2.2 1.4e-28 98.8 0.5 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK56979.1 - 0.00027 21.0 0.2 0.001 19.1 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase SH2_2 PF14633.6 KIK56979.1 - 0.05 13.0 0.4 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 SH2 domain ABC_tran PF00005.27 KIK56979.1 - 0.16 12.5 0.3 7.5 7.1 0.0 2.9 2 1 0 2 2 2 0 ABC transporter BCS1_N PF08740.11 KIK56980.1 - 1.9e-44 151.9 2.4 1.9e-44 151.9 2.4 2.4 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KIK56980.1 - 6.4e-15 55.8 0.0 4e-14 53.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK56980.1 - 0.00079 19.8 3.2 0.0011 19.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIK56980.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KIK56980.1 - 0.0096 16.4 7.3 0.38 11.2 6.6 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KIK56980.1 - 0.0099 15.7 6.1 4.7 6.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KIK56980.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KIK56980.1 - 0.034 13.3 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIK56980.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain YlbE PF14003.6 KIK56980.1 - 0.051 14.0 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 YlbE-like protein DDRGK PF09756.9 KIK56980.1 - 0.078 12.6 17.7 9.5 5.8 21.9 2.1 2 0 0 2 2 2 0 DDRGK domain NACHT PF05729.12 KIK56980.1 - 0.094 12.6 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KIK56980.1 - 0.11 12.7 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KIK56980.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) XRN_M PF17846.1 KIK56980.1 - 0.24 10.3 7.9 0.36 9.7 7.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF4887 PF16228.5 KIK56980.1 - 1.1 9.4 20.4 2.1 8.5 20.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) MPM1 PF17234.2 KIK56980.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.9 2 1 0 2 2 1 0 Mitochondrial peculiar membrane protein 1 DUF1974 PF09317.11 KIK56980.1 - 2.9 7.4 5.8 18 4.8 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) Macoilin PF09726.9 KIK56980.1 - 3.1 6.3 16.4 5.8 5.4 16.4 1.5 1 0 0 1 1 1 0 Macoilin family AAA_28 PF13521.6 KIK56980.1 - 4.7 7.4 7.1 7.2 6.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF3492 PF11997.8 KIK56980.1 - 5.5 6.7 5.9 2.6 7.7 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) RAB3GAP2_C PF14656.6 KIK56980.1 - 9.2 4.4 10.5 16 3.6 10.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CDtoxinA PF03498.14 KIK56982.1 - 0.03 13.9 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain SYS1 PF09801.9 KIK56983.1 - 1.2e-24 87.2 7.4 1.4e-23 83.6 7.4 2.0 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Rxt3 PF08642.10 KIK56985.1 - 6.4e-06 27.0 0.7 1.3e-05 26.0 0.7 1.8 1 1 1 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KIK56985.1 - 0.047 13.8 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 LCCL domain Nro1 PF12753.7 KIK56987.1 - 0.004 16.2 3.7 0.76 8.7 2.1 2.6 2 1 0 2 2 2 2 Nuclear pore complex subunit Nro1 Vta1_C PF18097.1 KIK56987.1 - 0.39 10.5 2.5 5.4 6.8 0.4 3.0 2 0 0 2 2 2 0 Vta1 C-terminal domain DPPIV_N PF00930.21 KIK56988.1 - 2.8e-92 309.2 0.6 4.7e-92 308.5 0.6 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KIK56988.1 - 4e-43 147.4 1.0 6.3e-43 146.7 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIK56988.1 - 7.7e-06 25.7 0.1 1.6e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KIK56988.1 - 0.0023 18.6 0.7 0.012 16.3 0.1 2.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK56988.1 - 0.0028 17.4 0.2 0.0052 16.5 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIK56988.1 - 0.0035 16.0 0.0 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 KIK56988.1 - 0.0062 15.5 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KIK56988.1 - 0.032 13.8 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PD40 PF07676.12 KIK56988.1 - 0.073 13.0 0.5 21 5.2 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SopE_GEF PF07487.13 KIK56990.1 - 0.15 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 SopE GEF domain F-box-like PF12937.7 KIK56994.1 - 5.5e-05 23.0 0.4 0.00025 20.9 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK56994.1 - 0.022 14.6 1.7 0.056 13.3 0.4 2.3 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK56995.1 - 6.5e-05 22.7 0.2 0.00017 21.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK56995.1 - 0.059 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain Ran_BP1 PF00638.18 KIK56996.1 - 2.2e-05 24.7 0.0 4.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Thioredoxin PF00085.20 KIK56997.1 - 6.2e-20 71.1 0.0 1.8e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK56997.1 - 0.00072 20.0 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIK56997.1 - 0.0088 16.2 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Trypan_PARP PF05887.11 KIK56997.1 - 0.59 10.1 21.2 1.2 9.1 21.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GPI-anchored PF10342.9 KIK56998.1 - 1.1e-09 38.9 2.7 1.1e-09 38.9 2.7 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_25 PF13649.6 KIK56999.1 - 5.7e-11 43.0 0.0 4.9e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK56999.1 - 1.7e-10 41.0 0.0 4e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK56999.1 - 1.7e-09 37.6 0.0 8.4e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK56999.1 - 4.9e-08 33.5 0.0 1.2e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK56999.1 - 2.1e-05 25.2 0.0 0.00024 21.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK56999.1 - 0.0006 19.2 0.0 0.0021 17.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KIK56999.1 - 0.00062 19.3 0.0 1.5 8.2 0.0 2.8 3 0 0 3 3 3 2 Putative methyltransferase GCD14 PF08704.10 KIK56999.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF21 PF01595.20 KIK57000.1 - 1.1e-36 126.1 0.5 1.8e-36 125.5 0.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIK57000.1 - 0.11 12.9 0.1 14 6.2 0.0 3.3 3 0 0 3 3 3 0 CBS domain AMP-binding PF00501.28 KIK57001.1 - 2.6e-26 92.2 0.0 3.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK57001.1 - 2.1e-06 28.1 0.1 6.3e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KIK57001.1 - 0.046 14.1 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 Phosphopantetheine attachment site DUF21 PF01595.20 KIK57002.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain AMP-binding PF00501.28 KIK57003.1 - 3.7e-28 98.3 0.0 5.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK57003.1 - 0.00062 20.0 0.1 0.0033 17.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KIK57003.1 - 0.0019 18.5 0.0 0.0063 16.8 0.0 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.16 KIK57004.1 - 6.8e-22 77.9 33.9 1.9e-19 69.8 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK57004.1 - 3.7e-06 26.1 2.6 3.7e-06 26.1 2.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK57006.1 - 6.9e-26 91.0 35.1 2e-23 82.9 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK57006.1 - 1e-07 31.2 2.0 1e-07 31.2 2.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK57006.1 - 1.9e-05 24.1 0.9 1.9e-05 24.1 0.9 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KIK57006.1 - 0.00047 18.7 0.6 0.00083 17.9 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HSF_DNA-bind PF00447.17 KIK57009.1 - 4.7e-33 113.7 1.6 5.2e-33 113.5 1.6 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KIK57009.1 - 0.031 14.7 0.0 0.056 13.9 0.0 1.5 1 1 0 1 1 1 0 Ets-domain Orbi_VP6 PF01516.16 KIK57010.1 - 2.4 7.6 4.5 3.3 7.1 4.5 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Yuri_gagarin PF15934.5 KIK57011.1 - 0.12 12.2 0.3 0.16 11.8 0.3 1.1 1 0 0 1 1 1 0 Yuri gagarin adh_short PF00106.25 KIK57012.1 - 9.7e-30 103.5 0.0 1.2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57012.1 - 2.9e-23 82.7 0.0 4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DJ-1_PfpI PF01965.24 KIK57014.1 - 2.4e-17 63.2 0.0 3.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Cupin_5 PF06172.11 KIK57014.1 - 0.12 12.6 0.3 0.2 11.8 0.1 1.6 2 0 0 2 2 2 0 Cupin superfamily (DUF985) DJ-1_PfpI PF01965.24 KIK57015.1 - 3.2e-18 66.1 0.0 4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Cupin_5 PF06172.11 KIK57015.1 - 0.12 12.6 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 Cupin superfamily (DUF985) Mt_ATP-synt_B PF05405.14 KIK57016.1 - 2.8e-42 144.1 10.9 3.7e-42 143.7 10.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cortex-I_coil PF09304.10 KIK57016.1 - 0.023 14.9 6.5 0.03 14.5 6.1 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF5623 PF18536.1 KIK57016.1 - 0.37 11.1 3.3 0.39 11.0 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5623) DUF1539 PF07560.11 KIK57016.1 - 0.43 10.7 4.6 0.47 10.5 2.6 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) SLATT_1 PF18181.1 KIK57016.1 - 0.82 9.6 9.3 0.051 13.5 2.4 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 stn_TNFRSF12A PF12191.8 KIK57017.1 - 0.081 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain F-box-like PF12937.7 KIK57018.1 - 5.4e-06 26.2 0.5 5.4e-06 26.2 0.5 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK57018.1 - 0.00075 19.3 0.5 0.0039 17.0 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK57019.1 - 7.1e-06 25.8 1.5 1.3e-05 25.0 1.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK57019.1 - 0.12 12.3 1.3 0.29 11.1 1.3 1.8 1 1 0 1 1 1 0 F-box domain Tannase PF07519.11 KIK57021.1 - 9.8e-114 380.8 0.0 1.2e-113 380.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KIK57021.1 - 0.00023 20.5 0.0 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK57021.1 - 0.0019 17.9 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK57021.1 - 0.068 12.6 0.2 0.14 11.6 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.22 KIK57022.1 - 8.1e-70 235.8 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.20 KIK57023.1 - 1.3e-19 70.7 0.0 5.3e-11 43.0 0.0 2.5 2 1 0 2 2 2 2 Rhodanese-like domain DIT1_PvcA PF05141.12 KIK57024.1 - 6.5e-73 245.6 0.0 8.5e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KIK57024.1 - 7.2e-25 88.3 0.0 1.7e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KIK57024.1 - 0.19 10.8 0.0 0.41 9.7 0.0 1.5 2 0 0 2 2 2 0 CsiD p450 PF00067.22 KIK57025.1 - 8.3e-66 222.6 0.0 1e-65 222.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 KIK57026.1 - 2.3 7.8 7.0 14 5.3 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 KIK57027.1 - 1.6e-28 99.7 56.3 6.7e-22 77.9 37.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1134 PF06577.12 KIK57027.1 - 0.062 13.1 0.4 3 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1134) LisH PF08513.11 KIK57032.1 - 0.00016 21.5 0.1 0.00026 20.8 0.1 1.4 1 0 0 1 1 1 1 LisH START PF01852.19 KIK57033.1 - 1.8e-17 63.4 0.2 1.9e-06 27.4 0.1 4.9 5 0 0 5 5 5 3 START domain Phos_pyr_kin PF08543.12 KIK57034.1 - 3.5e-09 36.4 0.0 5.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KIK57034.1 - 0.00013 21.4 0.0 0.00043 19.7 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Actin PF00022.19 KIK57035.1 - 1.2e-116 389.7 0.0 5.8e-116 387.5 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIK57035.1 - 0.0029 16.5 0.0 0.0062 15.4 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein Rab5-bind PF09311.11 KIK57039.1 - 0.078 12.4 0.4 0.15 11.4 0.1 1.5 2 0 0 2 2 2 0 Rabaptin-like protein Terpene_synth_C PF03936.16 KIK57040.1 - 0.021 14.2 0.1 0.031 13.6 0.1 1.5 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.16 KIK57041.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.16 KIK57042.1 - 0.035 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Rab5-bind PF09311.11 KIK57043.1 - 0.034 13.5 0.5 0.053 12.9 0.1 1.4 2 0 0 2 2 2 0 Rabaptin-like protein SPX PF03105.19 KIK57044.1 - 0.18 11.7 4.6 0.2 11.6 4.6 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KIK57044.1 - 0.21 10.4 3.5 0.2 10.4 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Amnionless PF14828.6 KIK57044.1 - 0.88 8.3 3.2 0.74 8.6 2.1 1.4 1 1 0 1 1 1 0 Amnionless p450 PF00067.22 KIK57045.1 - 1.2e-58 199.0 0.0 1.6e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Suv3_C_1 PF18147.1 KIK57047.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 p450 PF00067.22 KIK57049.1 - 2.1e-62 211.4 0.0 7e-62 209.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KIK57050.1 - 5.2e-08 32.9 10.5 8.3e-08 32.2 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK57050.1 - 8.7e-05 21.7 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_2 PF07719.17 KIK57050.1 - 0.29 11.4 2.2 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 KIK57051.1 - 1e-60 205.8 0.0 4e-60 203.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Carb_bind PF10645.9 KIK57053.1 - 4.5e-41 138.8 24.9 1.6e-20 73.1 6.5 2.1 2 0 0 2 2 2 2 Carbohydrate binding IGFL PF14653.6 KIK57053.1 - 0.00093 19.1 16.1 0.66 10.0 0.9 3.8 1 1 3 4 4 4 4 Insulin growth factor-like family Metallothio_6 PF05522.11 KIK57053.1 - 0.0033 17.9 6.4 0.065 13.7 0.9 2.2 2 0 0 2 2 2 2 Metallothionein APP_Cu_bd PF12924.7 KIK57053.1 - 0.09 13.5 7.5 0.58 10.9 0.6 2.9 3 0 0 3 3 3 0 Copper-binding of amyloid precursor, CuBD MSL2-CXC PF16682.5 KIK57053.1 - 0.71 10.0 12.0 7.8 6.7 0.4 3.8 4 0 0 4 4 4 0 CXC domain of E3 ubiquitin-protein ligase MSL2 QH-AmDH_gamma PF08992.11 KIK57053.1 - 4 7.5 9.6 11 6.1 0.5 3.6 1 1 3 4 4 4 0 Quinohemoprotein amine dehydrogenase, gamma subunit LysM PF01476.20 KIK57055.1 - 6.9e-28 96.4 0.0 1.3e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 LysM domain KASH_CCD PF14662.6 KIK57056.1 - 0.11 12.4 7.8 0.093 12.5 2.7 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Prp19 PF08606.11 KIK57056.1 - 1.9 8.6 13.6 1.4 9.0 1.3 3.8 1 1 4 5 5 5 0 Prp19/Pso4-like FAM76 PF16046.5 KIK57056.1 - 4 6.7 5.1 7 5.9 5.1 1.3 1 0 0 1 1 1 0 FAM76 protein HALZ PF02183.18 KIK57056.1 - 8.9 6.6 6.7 9.7 6.5 0.2 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper UPF0242 PF06785.11 KIK57056.1 - 9.6 6.3 7.1 21 5.1 7.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ubiquitin_2 PF14560.6 KIK57057.1 - 2.5e-23 82.3 0.0 3.9e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KIK57057.1 - 1.6e-13 50.5 0.3 2.4e-13 49.9 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 KIK57057.1 - 0.011 15.4 0.0 0.04 13.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family AAA PF00004.29 KIK57058.1 - 9.1e-96 317.3 0.0 1.5e-46 158.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK57058.1 - 3.7e-26 90.7 7.1 1.6e-12 47.0 0.2 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 KIK57058.1 - 1.3e-20 73.4 0.7 6.4e-20 71.1 0.8 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KIK57058.1 - 3.4e-14 52.9 0.0 1.6e-05 24.7 0.0 3.7 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIK57058.1 - 3.3e-13 50.1 0.0 1.5e-07 31.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 KIK57058.1 - 6.6e-12 45.0 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 KIK57058.1 - 8.9e-12 45.4 0.1 5.6e-06 26.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KIK57058.1 - 1.3e-11 44.7 0.2 3.3e-05 23.9 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK57058.1 - 2.1e-10 41.2 0.1 0.00065 20.1 0.0 4.2 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.13 KIK57058.1 - 2.6e-09 36.8 0.1 0.0018 17.5 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KIK57058.1 - 9e-09 35.7 0.2 0.055 13.7 0.1 4.0 3 2 0 3 3 2 2 AAA domain Vps4_C PF09336.10 KIK57058.1 - 8.7e-08 32.1 0.3 1.2e-06 28.4 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KIK57058.1 - 2.2e-07 30.8 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KIK57058.1 - 3.8e-07 29.8 0.3 0.025 14.1 0.0 3.6 3 1 0 3 3 3 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIK57058.1 - 4.7e-07 29.4 0.5 0.029 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK57058.1 - 1.8e-06 28.3 0.0 0.03 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KIK57058.1 - 2.1e-06 28.3 2.3 0.029 14.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KIK57058.1 - 3.3e-06 27.2 0.0 0.024 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KIK57058.1 - 4e-06 26.4 0.2 0.89 8.9 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 KIK57058.1 - 6.6e-06 25.8 1.9 0.4 10.2 0.0 3.6 2 2 1 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 KIK57058.1 - 6.8e-06 25.4 0.1 0.0066 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KIK57058.1 - 2.4e-05 24.7 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KIK57058.1 - 3.3e-05 23.6 0.0 0.51 10.0 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KIK57058.1 - 3.9e-05 24.2 0.0 0.21 12.1 0.0 3.5 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 KIK57058.1 - 5e-05 23.1 0.1 0.47 10.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 KIK57058.1 - 9.6e-05 21.9 0.3 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 KIK57058.1 - 0.00013 22.4 0.2 0.91 10.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 KIK57058.1 - 0.00017 21.5 0.0 0.3 10.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 KIK57058.1 - 0.00032 20.7 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KIK57058.1 - 0.00035 20.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KIK57058.1 - 0.00038 20.3 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIK57058.1 - 0.00069 19.5 0.9 0.87 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 KIK57058.1 - 0.00077 18.7 0.0 0.24 10.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KIK57058.1 - 0.00099 18.9 0.0 0.53 10.0 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIK57058.1 - 0.0012 18.2 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UFD1 PF03152.14 KIK57058.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Sigma54_activ_2 PF14532.6 KIK57058.1 - 0.003 17.7 0.0 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KIK57058.1 - 0.0036 17.0 0.7 2.9 7.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KIK57058.1 - 0.0046 16.9 0.2 1 9.2 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 KIK57058.1 - 0.0048 17.3 1.5 3.6 7.9 0.0 3.5 3 1 0 4 4 3 0 AAA domain ATPase_2 PF01637.18 KIK57058.1 - 0.0062 16.5 0.1 13 5.7 0.0 3.5 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KIK57058.1 - 0.0078 15.3 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIK57058.1 - 0.01 15.1 0.0 6 6.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 KIK57058.1 - 0.02 14.1 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 KIK57058.1 - 0.026 13.8 0.0 0.5 9.5 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain IPT PF01745.16 KIK57058.1 - 0.035 13.5 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 KIK57058.1 - 0.044 13.7 0.4 11 5.9 0.0 3.6 4 0 0 4 4 3 0 NTPase Molydop_binding PF01568.21 KIK57058.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Cytidylate_kin PF02224.18 KIK57058.1 - 0.056 13.2 0.0 8.6 6.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 KIK57058.1 - 0.25 10.3 0.1 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Hydin_ADK PF17213.3 KIK57058.1 - 2.5 8.3 4.8 32 4.7 0.0 3.9 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain DAGAT PF03982.13 KIK57059.1 - 1.8e-102 342.2 0.0 2.4e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AMP-binding PF00501.28 KIK57060.1 - 1.2e-45 155.9 0.0 1.6e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KIK57060.1 - 2e-09 36.8 4.3 0.0016 18.1 0.2 7.3 7 1 0 7 7 7 1 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KIK57060.1 - 1.4e-08 34.9 0.0 3.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site zf-RING_5 PF14634.6 KIK57060.1 - 0.001 19.0 2.2 0.0019 18.1 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK57060.1 - 0.0021 18.0 2.8 0.0051 16.8 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK57060.1 - 0.0037 17.1 0.7 0.0074 16.1 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AMP-binding_C PF13193.6 KIK57060.1 - 0.005 17.8 0.1 7 7.7 0.2 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Prok-RING_4 PF14447.6 KIK57060.1 - 0.0058 16.5 2.4 0.01 15.7 2.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIK57060.1 - 0.0059 16.5 1.1 0.013 15.4 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK57060.1 - 0.0065 16.3 1.4 0.012 15.5 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Hexapep_2 PF14602.6 KIK57060.1 - 0.024 14.4 5.3 2.5 7.9 1.4 4.6 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase zf-RING_2 PF13639.6 KIK57060.1 - 0.13 12.7 2.1 0.27 11.6 2.1 1.6 1 0 0 1 1 1 0 Ring finger domain 4HBT_2 PF13279.6 KIK57061.1 - 3.4e-13 50.1 0.0 4.6e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily 4HBT PF03061.22 KIK57061.1 - 6.7e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KIK57061.1 - 0.026 13.8 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Acyl-ACP thioesterase Zip PF02535.22 KIK57062.1 - 0.2 10.9 19.5 0.0077 15.5 4.8 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter Pkinase PF00069.25 KIK57063.1 - 3.4e-14 52.8 0.0 5.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57063.1 - 1.1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK57063.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family API5 PF05918.11 KIK57063.1 - 0.17 10.6 5.1 0.24 10.2 5.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Carb_bind PF10645.9 KIK57065.1 - 7.5e-37 125.3 22.6 1.4e-19 70.0 6.4 2.9 3 0 0 3 3 3 2 Carbohydrate binding Metallothio_6 PF05522.11 KIK57065.1 - 0.0068 16.9 0.5 0.0068 16.9 0.5 3.2 3 0 0 3 3 3 2 Metallothionein IGFL PF14653.6 KIK57065.1 - 0.24 11.4 25.7 5 7.2 3.8 4.3 1 1 3 4 4 4 0 Insulin growth factor-like family MSL2-CXC PF16682.5 KIK57065.1 - 1.6 8.9 13.8 20 5.4 0.0 4.3 2 1 2 4 4 4 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Presenilin PF01080.17 KIK57066.1 - 1.7 7.3 3.1 3.4 6.3 3.2 1.5 1 1 0 1 1 1 0 Presenilin WRW PF10206.9 KIK57067.1 - 0.023 15.0 0.0 2.1 8.8 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial F1F0-ATP synthase, subunit f SIC PF03482.13 KIK57067.1 - 5.5 7.3 5.3 0.76 10.0 0.4 2.2 2 0 0 2 2 2 0 sic protein repeat PAP2 PF01569.21 KIK57068.1 - 0.44 10.3 3.4 0.22 11.3 1.4 1.6 2 0 0 2 2 2 0 PAP2 superfamily TPT PF03151.16 KIK57071.1 - 0.018 14.4 0.3 0.027 13.8 0.3 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family zf-C2H2 PF00096.26 KIK57071.1 - 0.049 14.1 2.2 0.049 14.1 2.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Transposase_28 PF04195.12 KIK57071.1 - 0.085 13.1 2.2 0.11 12.8 0.6 2.0 2 0 0 2 2 2 0 Putative gypsy type transposon zf-met PF12874.7 KIK57071.1 - 0.53 10.8 6.8 0.16 12.4 2.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK57071.1 - 3.7 8.7 12.6 0.24 12.4 1.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK57071.1 - 4.8 7.8 8.1 0.76 10.3 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK57071.1 - 6.7 7.1 10.7 0.49 10.8 3.0 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KIK57073.1 - 4.7e-09 36.2 9.8 7.5e-09 35.6 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK57073.1 - 7.1e-05 22.0 0.0 9.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_2 PF07719.17 KIK57073.1 - 0.93 9.8 2.9 22 5.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Carb_bind PF10645.9 KIK57074.1 - 1.1e-40 137.6 25.0 1.6e-20 73.0 6.3 2.1 2 0 0 2 2 2 2 Carbohydrate binding IGFL PF14653.6 KIK57074.1 - 0.0046 16.9 16.4 0.87 9.6 0.8 3.9 1 1 3 4 4 4 4 Insulin growth factor-like family Metallothio_6 PF05522.11 KIK57074.1 - 0.027 14.9 7.1 0.2 12.2 0.9 2.2 2 0 0 2 2 2 0 Metallothionein APP_Cu_bd PF12924.7 KIK57074.1 - 0.2 12.4 6.8 2.2 9.1 0.3 3.0 3 1 0 3 3 3 0 Copper-binding of amyloid precursor, CuBD MSL2-CXC PF16682.5 KIK57074.1 - 2.9 8.1 15.1 15 5.8 0.7 3.8 2 1 2 4 4 4 0 CXC domain of E3 ubiquitin-protein ligase MSL2 QH-AmDH_gamma PF08992.11 KIK57074.1 - 5 7.2 10.8 10 6.2 0.9 3.6 1 1 3 4 4 4 0 Quinohemoprotein amine dehydrogenase, gamma subunit Carb_bind PF10645.9 KIK57075.1 - 3e-21 75.4 12.7 6.8e-20 71.0 10.7 2.2 2 0 0 2 2 2 2 Carbohydrate binding IGFL PF14653.6 KIK57075.1 - 0.15 12.1 6.3 1.4 9.0 1.2 2.4 1 1 1 2 2 2 0 Insulin growth factor-like family Amb_V_allergen PF03913.13 KIK57075.1 - 0.27 11.2 5.7 2 8.4 0.2 3.0 3 0 0 3 3 3 0 Amb V Allergen QH-AmDH_gamma PF08992.11 KIK57075.1 - 0.46 10.5 4.4 12 6.0 0.7 3.0 1 1 2 3 3 3 0 Quinohemoprotein amine dehydrogenase, gamma subunit Phage_holin_2_3 PF16080.5 KIK57077.1 - 0.023 14.5 0.7 0.052 13.3 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Carb_bind PF10645.9 KIK57080.1 - 9.7e-38 128.2 22.1 2.3e-21 75.7 8.8 2.1 2 0 0 2 2 2 2 Carbohydrate binding Metallothio_6 PF05522.11 KIK57080.1 - 0.004 17.6 3.0 0.83 10.2 0.1 2.2 2 0 0 2 2 2 2 Metallothionein IGFL PF14653.6 KIK57080.1 - 0.0083 16.1 14.1 1.1 9.2 3.5 3.5 1 1 3 4 4 4 3 Insulin growth factor-like family APP_Cu_bd PF12924.7 KIK57080.1 - 0.052 14.3 3.1 5.3 7.8 0.5 2.5 2 1 0 2 2 2 0 Copper-binding of amyloid precursor, CuBD MSL2-CXC PF16682.5 KIK57080.1 - 0.22 11.7 5.2 15 5.8 0.3 3.3 3 1 0 3 3 3 0 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF2235 PF09994.9 KIK57081.1 - 1.3e-63 215.1 0.0 1.7e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sperm_Ag_HE2 PF05324.13 KIK57082.1 - 0.0093 16.4 1.1 0.012 16.0 1.1 1.2 1 0 0 1 1 1 1 Sperm antigen HE2 COX7B PF05392.11 KIK57082.1 - 0.075 12.7 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Phage_holin_2_3 PF16080.5 KIK57083.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family HP1 NAD_binding_10 PF13460.6 KIK57084.1 - 1e-08 35.3 0.0 2.4e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK57084.1 - 1e-06 28.4 0.0 2e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIK57084.1 - 0.00029 21.3 0.0 0.00081 19.8 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIK57084.1 - 0.016 14.3 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein SPRY PF00622.28 KIK57085.1 - 3.5e-11 43.3 0.1 6.1e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 SPRY domain IFT57 PF10498.9 KIK57087.1 - 0.0054 15.8 1.7 0.0086 15.1 1.7 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 APG6_N PF17675.1 KIK57087.1 - 0.0071 16.9 3.7 0.0071 16.9 3.7 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF812 PF05667.11 KIK57087.1 - 0.02 13.8 3.4 0.029 13.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IFT20 PF14931.6 KIK57087.1 - 0.067 13.4 3.6 5.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF5623 PF18536.1 KIK57087.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) TMF_TATA_bd PF12325.8 KIK57087.1 - 0.19 12.0 8.4 7.6 6.8 0.8 3.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding JAKMIP_CC3 PF16034.5 KIK57087.1 - 0.26 11.2 1.9 0.51 10.3 1.9 1.5 1 0 0 1 1 1 0 JAKMIP CC3 domain GAS PF13851.6 KIK57087.1 - 0.33 10.3 4.3 0.056 12.8 0.6 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.6 KIK57087.1 - 0.55 10.4 7.8 0.49 10.6 1.2 2.8 1 1 1 2 2 2 0 Up-regulated During Septation DUF948 PF06103.11 KIK57087.1 - 1.2 9.4 3.7 16 5.8 0.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 KIK57087.1 - 1.3 8.9 4.9 1.2 9.0 0.6 2.6 3 0 0 3 3 3 0 Septum formation initiator Spc24 PF08286.11 KIK57087.1 - 1.9 8.8 8.3 5.5 7.3 1.1 2.9 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KIK57087.1 - 2.2 8.2 4.5 9 6.3 0.5 2.9 3 0 0 3 3 3 0 Prefoldin subunit TLE_N PF03920.15 KIK57087.1 - 2.3 8.3 3.9 20 5.3 0.1 2.9 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Lipase_3 PF01764.25 KIK57088.1 - 1.1e-24 87.0 0.1 1.4e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Lipase (class 3) Cellulase PF00150.18 KIK57089.1 - 7.8e-13 48.5 0.3 2.4e-12 46.9 0.3 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KIK57090.1 - 2.6e-13 50.1 0.1 7.2e-13 48.6 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KIK57091.1 - 3.5e-12 46.3 0.4 2.1e-11 43.8 0.4 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 KIK57092.1 - 1.7e-10 40.5 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ytp1 PF10355.9 KIK57093.1 - 1.1e-56 192.0 20.0 3.7e-56 190.4 15.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIK57093.1 - 1.2e-27 95.8 0.2 1.2e-27 95.8 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KIK57093.1 - 0.0014 18.8 5.1 0.0014 18.8 5.1 3.3 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 p450 PF00067.22 KIK57094.1 - 4.3e-51 174.1 0.3 9.3e-49 166.4 0.3 3.1 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK57095.1 - 3.9e-51 174.3 0.3 4.6e-33 114.7 0.0 3.2 2 2 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIK57096.1 - 7.8e-67 226.0 0.0 7.1e-66 222.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF3140 PF11338.8 KIK57096.1 - 0.52 10.8 1.9 1.3 9.5 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3140) p450 PF00067.22 KIK57097.1 - 0.0098 14.7 0.1 0.011 14.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK57098.1 - 1.5e-48 165.7 0.0 2.8e-48 164.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 PUB_1 PF18486.1 KIK57098.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain F-box PF00646.33 KIK57099.1 - 1.8e-08 34.1 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK57099.1 - 2.4e-05 24.1 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK57099.1 - 0.016 15.0 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 F-box MFS_1 PF07690.16 KIK57101.1 - 1e-18 67.5 38.1 9e-17 61.0 20.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4598 PF15370.6 KIK57103.1 - 1.3e-18 67.5 14.2 2.4e-17 63.4 14.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) SPX PF03105.19 KIK57103.1 - 0.049 13.6 12.1 0.06 13.3 12.1 1.2 1 0 0 1 1 1 0 SPX domain DLIC PF05783.11 KIK57103.1 - 0.076 11.8 1.2 0.13 11.1 1.2 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Nop14 PF04147.12 KIK57103.1 - 0.14 10.4 5.5 0.17 10.1 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KIK57103.1 - 0.3 10.4 10.7 0.37 10.1 10.7 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KIK57103.1 - 1.1 8.9 7.9 1.9 8.2 7.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 KIK57103.1 - 1.4 8.3 11.4 2.1 7.7 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DNA_pol_phi PF04931.13 KIK57103.1 - 1.7 6.7 9.9 2.4 6.1 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Apt1 PF10351.9 KIK57103.1 - 2.2 7.1 13.2 2.9 6.7 13.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Chorion_2 PF03964.15 KIK57103.1 - 2.9 8.8 12.9 0.31 11.9 3.1 2.6 2 0 0 2 2 2 0 Chorion family 2 PI3K_1B_p101 PF10486.9 KIK57103.1 - 4.1 5.1 12.2 4.7 4.9 12.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 KIK57103.1 - 4.9 5.6 10.1 6.2 5.2 10.1 1.2 1 0 0 1 1 1 0 Macoilin family MR_MLE_C PF13378.6 KIK57104.1 - 4.1e-44 150.8 0.0 5.8e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIK57104.1 - 2.5e-10 40.6 0.0 5.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UBX PF00789.20 KIK57105.1 - 8.5e-12 45.1 0.5 2.2e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KIK57105.1 - 9.2e-06 25.5 0.0 2.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 KIK57105.1 - 0.011 16.0 0.1 0.024 15.0 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 KIK57105.1 - 0.035 14.0 0.3 0.078 12.9 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain CENP-S PF15630.6 KIK57105.1 - 0.059 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 CENP-S protein DUF572 PF04502.13 KIK57105.1 - 0.071 12.7 15.2 0.11 12.1 15.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 KIK57105.1 - 2.7 5.0 11.2 3.3 4.7 11.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 KIK57105.1 - 6.6 6.7 20.6 8.7 6.3 20.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region F-box-like PF12937.7 KIK57106.1 - 3.2e-08 33.4 2.7 8.6e-08 32.0 1.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK57106.1 - 3.1e-07 30.1 2.3 6.5e-07 29.1 2.3 1.6 1 0 0 1 1 1 1 F-box domain WAPL PF07814.13 KIK57107.1 - 1.3e-11 43.9 3.1 5e-10 38.7 1.1 2.8 3 1 0 3 3 3 2 Wings apart-like protein regulation of heterochromatin p450 PF00067.22 KIK57108.1 - 8.1e-65 219.3 0.0 2.6e-64 217.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3140 PF11338.8 KIK57108.1 - 3 8.3 4.7 44 4.6 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3140) RBM1CTR PF08081.11 KIK57109.1 - 1.1 9.3 12.1 0.28 11.3 0.9 2.4 1 1 1 2 2 2 0 RBM1CTR (NUC064) family WAPL PF07814.13 KIK57110.1 - 1.6e-10 40.4 2.0 3.1e-10 39.4 2.0 1.4 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin p450 PF00067.22 KIK57111.1 - 4.3e-65 220.3 0.0 1e-64 219.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK57112.1 - 5.9e-62 209.9 0.1 1.9e-43 148.9 0.0 2.8 2 2 0 2 2 2 2 Cytochrome P450 DUF3140 PF11338.8 KIK57112.1 - 3.1 8.3 4.9 43 4.6 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3140) FB_lectin PF07367.11 KIK57113.1 - 8.1e-56 187.8 1.6 9.1e-56 187.7 1.6 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin FB_lectin PF07367.11 KIK57114.1 - 9.8e-61 203.8 0.4 1.1e-60 203.6 0.4 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin Tannase PF07519.11 KIK57117.1 - 6.3e-109 365.0 4.3 9.9e-109 364.3 4.3 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.16 KIK57118.1 - 1e-18 67.4 28.4 1e-18 67.4 28.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box PF00646.33 KIK57119.1 - 1.7e-07 30.9 0.5 5.9e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK57119.1 - 1.8e-05 24.5 0.1 5.3e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK57119.1 - 0.026 14.4 0.2 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 F-box DUF445 PF04286.12 KIK57119.1 - 0.042 13.7 0.1 0.12 12.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) ATP-synt_E_2 PF08112.11 KIK57119.1 - 0.07 13.4 0.5 0.22 11.8 0.5 1.8 1 0 0 1 1 1 0 ATP synthase epsilon subunit CNH PF00780.22 KIK57120.1 - 1.3e-53 182.3 0.0 2e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIK57120.1 - 2.6e-08 34.1 0.0 2.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 KIK57120.1 - 0.022 14.6 0.7 0.061 13.2 0.1 2.0 2 0 0 2 2 2 0 PH domain CNH PF00780.22 KIK57121.1 - 2.2e-53 181.7 0.0 2.8e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 CNH domain F-box PF00646.33 KIK57122.1 - 9.2e-09 35.0 0.4 3.2e-08 33.2 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK57122.1 - 1.4e-06 28.1 1.0 8.1e-06 25.6 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIK57122.1 - 0.0095 15.8 0.1 0.099 12.5 0.0 2.5 2 0 0 2 2 2 1 F-box Actin_micro PF17003.5 KIK57122.1 - 0.45 9.6 4.4 0.42 9.7 1.2 2.3 3 0 0 3 3 3 0 Putative actin-like family NADH-G_4Fe-4S_3 PF10588.9 KIK57122.1 - 0.71 9.5 5.8 0.35 10.4 0.1 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region RhoGEF PF00621.20 KIK57123.1 - 9.2e-33 114.0 2.2 5.4e-28 98.5 0.0 3.9 4 0 0 4 4 4 2 RhoGEF domain CNH PF00780.22 KIK57123.1 - 6.4e-27 94.9 0.0 5.3e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 CNH domain PH_5 PF15405.6 KIK57123.1 - 7.1e-09 35.9 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Glyoxal_oxid_N PF07250.11 KIK57124.1 - 4.4e-29 101.4 0.2 8e-14 51.4 0.0 4.8 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK57124.1 - 6.4e-24 84.1 0.4 1.6e-23 82.8 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.16 KIK57124.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.6 KIK57124.1 - 0.25 11.4 8.1 0.86 9.7 0.1 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain TAF4 PF05236.14 KIK57124.1 - 9 6.0 9.7 6.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Transcription initiation factor TFIID component TAF4 family CHAT PF12770.7 KIK57126.1 - 4.3e-31 108.4 0.0 6.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK57126.1 - 0.0012 18.6 0.4 0.2 11.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK57126.1 - 0.0062 17.2 0.0 1.2 9.8 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK57126.1 - 0.016 15.0 0.2 0.016 15.0 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK57126.1 - 0.023 14.9 0.3 3.8 8.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 KIK57126.1 - 0.042 14.3 0.2 0.61 10.5 0.0 2.8 3 0 0 3 3 2 0 Snapin/Pallidin TPR_12 PF13424.6 KIK57126.1 - 0.083 13.2 3.2 2.6 8.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK57126.1 - 0.1 12.8 7.3 2.5 8.4 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KIK57126.1 - 0.12 13.1 0.0 1.4e+02 3.4 0.0 3.6 3 0 0 3 3 3 0 Sel1 repeat TPR_7 PF13176.6 KIK57126.1 - 0.14 12.3 0.7 3.5 7.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK57126.1 - 0.19 11.4 3.0 44 3.9 0.2 4.7 5 0 0 5 5 5 0 TPR repeat DUF3786 PF12654.7 KIK57127.1 - 0.19 11.3 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Alpha_kinase PF02816.18 KIK57128.1 - 5.5e-07 29.9 0.0 8.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Ribosomal_L39 PF00832.20 KIK57130.1 - 1.6 8.4 4.4 0.59 9.8 1.4 1.9 2 0 0 2 2 2 0 Ribosomal L39 protein OTT_1508_deam PF14441.6 KIK57131.1 - 0.00019 21.3 2.4 0.00035 20.5 2.4 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Trp_DMAT PF11991.8 KIK57132.1 - 5.6e-65 220.1 0.0 8.6e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase LcrR PF09621.10 KIK57132.1 - 0.12 11.9 0.0 0.39 10.2 0.0 1.8 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Trp_DMAT PF11991.8 KIK57133.1 - 1.4e-61 208.9 0.0 2.2e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase LcrR PF09621.10 KIK57133.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) Aldolase_II PF00596.21 KIK57134.1 - 5.9e-25 88.3 0.3 7.6e-25 87.9 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAD-oxidase_C PF02913.19 KIK57135.1 - 1.2e-53 182.4 0.1 2.8e-53 181.1 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK57135.1 - 1.3e-21 76.8 0.0 2.6e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain PilZ PF07238.14 KIK57135.1 - 0.041 14.2 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 PilZ domain Sugar_tr PF00083.24 KIK57136.1 - 2.4e-68 231.1 19.2 1.5e-35 123.0 1.2 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KIK57136.1 - 2e-11 43.4 28.0 3.6e-06 26.1 4.6 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily HIT PF01230.23 KIK57137.1 - 2e-22 79.8 0.1 3.8e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK57137.1 - 3.9e-15 56.3 0.0 6.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIK57137.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Peptidase_C97 PF05903.14 KIK57138.1 - 2.2e-32 111.9 0.1 1.9e-31 109.0 0.1 2.1 1 1 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KIK57138.1 - 1.4e-30 106.5 0.0 2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KIK57138.1 - 1.4e-13 50.7 0.0 3.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK57138.1 - 0.00015 22.2 0.0 0.00041 20.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KIK57138.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF4581 PF15167.6 KIK57138.1 - 0.21 11.7 0.1 3.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4581) Carn_acyltransf PF00755.20 KIK57139.1 - 1.6e-191 637.9 0.0 1.9e-191 637.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fungal_trans PF04082.18 KIK57140.1 - 1.1e-16 60.7 2.3 1.9e-16 59.9 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK57140.1 - 0.00052 20.1 13.2 0.00052 20.1 13.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNB PF00773.19 KIK57140.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 RNB domain Fungal_trans PF04082.18 KIK57141.1 - 2.1e-14 53.2 0.0 4.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK57141.1 - 4.3e-05 23.6 13.9 0.0001 22.3 13.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CMAS PF02353.20 KIK57142.1 - 4.4e-59 200.0 0.3 5.8e-46 157.0 0.0 3.0 2 1 1 3 3 3 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK57142.1 - 1.4e-08 35.3 0.0 3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KIK57142.1 - 4.2e-05 23.3 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 KIK57142.1 - 6.8e-05 23.4 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK57142.1 - 0.00029 20.4 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIK57142.1 - 0.001 19.8 0.0 0.0024 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57142.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIK57142.1 - 0.0056 17.7 0.0 0.017 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIK57142.1 - 0.0059 15.7 0.0 0.06 12.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 KIK57142.1 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KIK57142.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KIK57142.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KIK57142.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 KIK57142.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase HetR_C PF18460.1 KIK57142.1 - 0.22 11.5 1.9 0.46 10.4 0.1 2.4 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain GPI-anchored PF10342.9 KIK57145.1 - 1.5e-06 28.8 0.1 2.1e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KIK57146.1 - 2.4e-06 28.2 1.0 2.4e-06 28.2 1.0 3.1 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KIK57146.1 - 0.46 9.6 22.4 0.57 9.3 22.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DPBB_1 PF03330.18 KIK57147.1 - 0.0026 18.0 0.1 0.011 16.0 0.1 2.2 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIK57147.1 - 0.031 14.1 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Barwin family DUF35_N PF12172.8 KIK57147.1 - 0.097 12.6 7.4 0.15 12.0 0.3 3.8 3 1 1 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SH3_9 PF14604.6 KIK57148.1 - 5.5e-23 80.6 1.3 1.9e-13 50.0 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KIK57148.1 - 5.7e-22 77.1 0.4 1.6e-10 40.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIK57148.1 - 1.5e-20 72.6 0.1 1.1e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KIK57148.1 - 3.4e-13 49.2 4.3 5.8e-13 48.5 4.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.23 KIK57148.1 - 2e-12 47.2 1.6 5.7e-12 45.8 0.6 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.11 KIK57148.1 - 0.00016 21.9 0.2 0.00039 20.6 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain eRF1_2 PF03464.15 KIK57148.1 - 0.074 13.4 0.7 0.33 11.3 0.4 2.1 2 1 0 2 2 2 0 eRF1 domain 2 C1_2 PF03107.16 KIK57148.1 - 0.082 13.2 1.5 0.18 12.2 1.5 1.6 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 KIK57148.1 - 0.27 10.8 2.3 0.65 9.6 2.3 1.6 1 0 0 1 1 1 0 PHD-finger DUF4298 PF14131.6 KIK57148.1 - 0.4 10.7 8.0 3.6 7.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) Hemerythrin PF01814.23 KIK57150.1 - 1.2e-12 48.6 5.3 1.7e-12 48.1 5.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Metallothio_11 PF02066.15 KIK57151.1 - 0.073 13.3 1.7 0.19 11.9 0.5 2.2 2 0 0 2 2 2 0 Metallothionein family 11 HECW1_helix PF18436.1 KIK57151.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 CAF1 PF04857.20 KIK57152.1 - 8.7e-16 58.0 0.1 5.6e-08 32.3 0.1 3.2 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 KIK57152.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily Rif1_N PF12231.8 KIK57153.1 - 0.0022 17.0 0.1 0.027 13.5 0.0 2.3 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Gag_p6 PF08705.11 KIK57153.1 - 0.027 14.7 0.1 0.079 13.2 0.1 1.8 1 0 0 1 1 1 0 Gag protein p6 F-box PF00646.33 KIK57154.1 - 0.01 15.7 0.1 0.036 14.0 0.1 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIK57154.1 - 0.045 13.7 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 F-box-like 2OG-FeII_Oxy_3 PF13640.6 KIK57155.1 - 0.00053 20.8 0.0 0.0011 19.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIK57156.1 - 0.0006 20.7 0.0 0.0012 19.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIK57157.1 - 4.2e-10 40.4 0.0 1e-09 39.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KIK57157.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily XPA_C PF05181.12 KIK57158.1 - 3.9e-09 36.3 0.6 0.0016 18.4 0.3 2.4 2 0 0 2 2 2 2 XPA protein C-terminus DUF1153 PF06627.11 KIK57158.1 - 0.034 14.3 0.3 12 6.1 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1153) CDC45 PF02724.14 KIK57158.1 - 1.9 6.7 11.0 2.1 6.5 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein GPI-anchored PF10342.9 KIK57159.1 - 0.0028 18.4 1.5 0.0028 18.4 1.5 2.9 1 1 1 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KIK57159.1 - 1.7 7.7 17.6 1.7 7.7 17.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GPI-anchored PF10342.9 KIK57160.1 - 5.2e-06 27.1 0.1 8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CorA PF01544.18 KIK57161.1 - 6e-13 48.8 2.6 1.6e-12 47.3 0.6 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PrgI PF12666.7 KIK57161.1 - 0.025 15.3 2.5 0.048 14.4 2.5 1.4 1 0 0 1 1 1 0 PrgI family protein Claudin_3 PF06653.11 KIK57161.1 - 0.036 14.0 3.4 0.057 13.4 3.4 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like TcpE PF12648.7 KIK57161.1 - 0.049 14.2 2.0 0.096 13.2 2.0 1.4 1 0 0 1 1 1 0 TcpE family DUF1664 PF07889.12 KIK57162.1 - 0.0018 18.3 2.3 0.08 13.0 1.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 KIK57162.1 - 0.0019 18.7 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 Syntaxin 6, N-terminal COG2 PF06148.11 KIK57162.1 - 0.0078 16.3 1.6 0.017 15.2 1.6 1.5 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.21 KIK57162.1 - 0.013 15.1 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein Laminin_II PF06009.12 KIK57162.1 - 0.021 14.8 0.3 0.035 14.1 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.12 KIK57162.1 - 0.021 15.3 2.4 0.051 14.0 2.4 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 KIK57162.1 - 0.059 14.0 0.6 0.089 13.4 0.6 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DLP_helical PF18709.1 KIK57162.1 - 0.063 12.5 0.3 0.085 12.1 0.3 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Metal_resist PF13801.6 KIK57162.1 - 0.071 13.3 5.9 0.35 11.0 5.0 2.3 1 1 1 2 2 2 0 Heavy-metal resistance Rootletin PF15035.6 KIK57162.1 - 0.085 12.9 3.6 0.15 12.1 3.6 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1640 PF07798.11 KIK57162.1 - 0.089 12.8 1.4 0.13 12.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) LXG PF04740.12 KIK57162.1 - 0.092 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Bacillus_HBL PF05791.11 KIK57162.1 - 0.094 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SKA2 PF16740.5 KIK57162.1 - 0.11 12.2 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FlxA PF14282.6 KIK57162.1 - 0.13 12.2 0.9 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 FlxA-like protein FlaC_arch PF05377.11 KIK57162.1 - 0.17 12.3 1.1 0.61 10.5 0.5 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 KIK57162.1 - 0.17 12.2 1.3 0.56 10.5 1.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein BLOC1_2 PF10046.9 KIK57162.1 - 0.17 12.2 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.9 KIK57162.1 - 0.18 10.8 0.2 0.24 10.3 0.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KIK57162.1 - 0.21 10.5 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phlebovirus_NSM PF07246.11 KIK57162.1 - 1.1 8.6 3.0 1.5 8.1 3.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M EBP PF05241.12 KIK57164.1 - 8.4e-68 227.3 8.4 9.8e-68 227.1 8.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein CytB6-F_Fe-S PF08802.10 KIK57164.1 - 0.2 11.7 2.6 0.33 11.0 0.3 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Glyco_hydro_cc PF11790.8 KIK57165.1 - 8.6e-63 212.1 3.2 9.1e-62 208.7 3.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core INO80_Ies4 PF08193.11 KIK57165.1 - 0.071 13.1 6.1 0.11 12.5 6.1 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 DUF2517 PF10725.9 KIK57165.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) DUF3439 PF11921.8 KIK57165.1 - 0.33 10.9 8.5 0.6 10.1 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_M9_N PF08453.10 KIK57166.1 - 0.025 14.3 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M9 N-terminal AnfG_VnfG PF03139.15 KIK57166.1 - 0.049 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Mon1 PF03164.14 KIK57167.1 - 5.4e-101 338.6 0.0 1.2e-74 251.8 0.0 2.2 2 0 0 2 2 2 2 Trafficking protein Mon1 Shadoo PF14999.6 KIK57167.1 - 0.1 12.7 0.5 1.8 8.7 0.3 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective zf-MYND PF01753.18 KIK57168.1 - 3.4e-10 39.8 15.6 5.5e-10 39.2 15.6 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK57168.1 - 0.21 11.9 12.7 0.37 11.1 12.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding p450 PF00067.22 KIK57169.1 - 1.1e-48 166.2 0.0 1.3e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK57170.1 - 4.5e-49 167.4 0.0 5.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.20 KIK57171.1 - 5.3e-38 131.2 0.1 2.7e-35 122.3 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK57171.1 - 0.0004 20.0 0.1 0.15 11.5 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family BTB PF00651.31 KIK57173.1 - 3.5e-05 24.0 0.0 7.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SHE3 PF17078.5 KIK57174.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Zn_clus PF00172.18 KIK57175.1 - 5.2e-09 36.1 7.9 9.8e-09 35.2 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CRD PF17979.1 KIK57176.1 - 1.3e-13 51.4 0.5 1.3e-13 51.4 0.5 2.3 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 KIK57176.1 - 1.6e-06 27.8 13.9 1.6e-06 27.8 13.9 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK57176.1 - 1.1e-05 25.6 14.0 1.1e-05 25.6 14.0 3.8 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK57176.1 - 0.00023 21.0 11.5 0.00023 21.0 11.5 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK57176.1 - 0.0006 19.6 13.1 0.0006 19.6 13.1 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK57176.1 - 0.0049 16.8 13.4 0.0049 16.8 13.4 3.3 4 0 0 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK57176.1 - 0.0063 16.4 12.1 0.0063 16.4 12.1 3.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIK57176.1 - 0.013 15.3 8.6 0.063 13.2 8.6 2.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIK57176.1 - 0.18 12.1 12.8 0.11 12.8 9.0 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C4H2 PF10146.9 KIK57176.1 - 4.1 7.7 6.9 17 5.7 3.5 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Peptidase_S39 PF02122.15 KIK57177.1 - 0.18 11.3 0.2 0.34 10.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase S39 Kelch_6 PF13964.6 KIK57179.1 - 4.1e-21 74.5 2.5 1.7e-05 24.9 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KIK57179.1 - 1.7e-18 65.9 0.4 0.00015 21.3 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KIK57179.1 - 9.6e-15 53.9 7.6 0.0043 17.0 0.0 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KIK57179.1 - 1.8e-14 53.5 1.6 0.0026 17.7 0.0 5.1 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK57179.1 - 2e-12 46.8 2.1 0.0025 17.7 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KIK57179.1 - 1.1e-09 38.3 2.9 2.9e-06 27.4 0.0 5.4 6 0 0 6 6 6 1 Galactose oxidase, central domain BTB PF00651.31 KIK57179.1 - 0.0054 16.9 0.2 0.25 11.6 0.3 2.3 2 0 0 2 2 2 1 BTB/POZ domain SEO_N PF14576.6 KIK57180.1 - 0.047 12.9 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus FKBP_C PF00254.28 KIK57182.1 - 6e-32 109.8 0.0 7e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 KIK57184.1 - 7.1e-66 222.3 0.0 8.7e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57184.1 - 7.9e-40 136.8 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK57184.1 - 0.0016 18.4 0.5 0.15 11.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK57184.1 - 0.0027 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DHOR PF06537.11 KIK57184.1 - 0.018 13.7 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase Ral PF11058.8 KIK57184.1 - 0.022 14.3 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Antirestriction protein Ral Kdo PF06293.14 KIK57184.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIK57184.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 IGR PF09597.10 KIK57185.1 - 5e-18 64.9 0.4 7.5e-18 64.4 0.4 1.3 1 0 0 1 1 1 1 IGR protein motif TGS PF02824.21 KIK57185.1 - 0.13 12.3 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 TGS domain zf-C2H2_4 PF13894.6 KIK57186.1 - 0.0035 18.1 8.3 0.6 11.1 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger PBP1_TM PF14812.6 KIK57186.1 - 0.0048 17.2 6.0 0.012 16.0 6.0 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2HE PF16278.5 KIK57186.1 - 0.085 13.3 1.0 0.21 12.1 0.1 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CDC45 PF02724.14 KIK57186.1 - 0.12 10.7 1.5 0.14 10.4 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 KIK57186.1 - 0.24 11.9 10.8 2.5 8.7 0.1 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK57186.1 - 0.33 11.3 2.3 5.3 7.4 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Rrn6 PF10214.9 KIK57186.1 - 0.62 8.5 5.4 0.8 8.1 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BUD22 PF09073.10 KIK57186.1 - 0.85 8.9 9.8 0.71 9.1 8.5 1.5 2 0 0 2 2 2 0 BUD22 CENP-B_dimeris PF09026.10 KIK57186.1 - 0.98 9.8 10.0 2 8.9 10.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FHA PF00498.26 KIK57187.1 - 9.3e-16 58.0 0.0 1.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK57187.1 - 2.7e-05 24.4 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain p450 PF00067.22 KIK57188.1 - 5.1e-48 164.0 0.0 6.2e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK57189.1 - 4e-45 154.4 0.0 4.7e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stm1_N PF09598.10 KIK57191.1 - 0.52 11.2 0.0 0.52 11.2 0.0 5.8 5 1 1 6 6 6 0 Stm1 RCR PF12273.8 KIK57191.1 - 1.1 9.9 4.1 0.42 11.3 0.7 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CHASE3 PF05227.13 KIK57191.1 - 3 7.8 16.6 1.8 8.5 9.8 2.8 2 0 0 2 2 2 0 CHASE3 domain DUF4201 PF13870.6 KIK57191.1 - 3.5 7.3 19.3 8.7 6.0 9.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.6 KIK57191.1 - 4.7 7.4 15.0 0.38 10.9 1.4 4.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Golgin_A5 PF09787.9 KIK57191.1 - 6 6.2 25.8 0.47 9.9 13.2 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 AMP-binding PF00501.28 KIK57192.1 - 5.5e-20 71.4 0.1 8.2e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIK57192.1 - 0.0037 17.6 0.0 0.0085 16.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.20 KIK57192.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain MFS_1 PF07690.16 KIK57193.1 - 9.2e-25 87.3 29.9 9.2e-25 87.3 29.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK57193.1 - 1.1e-07 31.1 3.5 1.1e-07 31.1 3.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK57193.1 - 1.1e-05 25.0 1.7 1.1e-05 25.0 1.7 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB GPI-anchored PF10342.9 KIK57197.1 - 0.00027 21.6 1.7 0.00051 20.7 0.2 2.2 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIK57197.1 - 0.036 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Gag_MA PF01140.19 KIK57197.1 - 0.12 12.1 0.4 0.34 10.7 0.4 1.7 1 0 0 1 1 1 0 Matrix protein (MA), p15 SCF PF02404.15 KIK57197.1 - 0.24 10.7 0.4 0.53 9.6 0.2 1.6 2 0 0 2 2 2 0 Stem cell factor SKG6 PF08693.10 KIK57197.1 - 0.29 10.6 2.5 0.16 11.4 0.3 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain zf-MYND PF01753.18 KIK57198.1 - 4e-11 42.8 13.7 6.3e-11 42.2 13.7 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK57198.1 - 0.3 11.4 11.2 0.53 10.6 11.2 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RPAP2_Rtr1 PF04181.13 KIK57198.1 - 2.7 8.4 9.2 8.6 6.8 9.2 1.7 1 1 0 1 1 1 0 Rtr1/RPAP2 family F-box PF00646.33 KIK57200.1 - 0.92 9.5 4.2 0.22 11.4 0.4 1.9 2 0 0 2 2 2 0 F-box domain PRIMA1 PF16101.5 KIK57200.1 - 1.7 8.7 6.3 0.22 11.6 1.5 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 COPIIcoated_ERV PF07970.12 KIK57202.1 - 2.4e-79 266.2 1.0 3.9e-79 265.6 1.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIK57202.1 - 1.1e-25 89.8 2.4 1.3e-25 89.5 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) F-box-like PF12937.7 KIK57203.1 - 1.1e-05 25.2 1.8 3.3e-05 23.7 1.1 2.3 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 KIK57204.1 - 1.1e-16 60.9 16.1 5.6e-05 23.8 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57204.1 - 6e-11 42.5 0.1 0.006 16.8 0.0 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Sec1 PF00995.23 KIK57207.1 - 1.3e-122 411.0 0.1 1.6e-122 410.7 0.1 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 KIK57207.1 - 2.5e-79 266.2 0.1 3.9e-79 265.6 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIK57207.1 - 2.1e-21 76.1 0.2 2.1e-21 76.1 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) EF-hand_14 PF17959.1 KIK57207.1 - 0.089 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain DUF727 PF05303.12 KIK57208.1 - 5.3e-07 29.7 0.4 7.6e-05 22.7 0.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Talin_middle PF09141.10 KIK57208.1 - 0.0037 17.3 0.3 0.0048 16.9 0.3 1.3 1 1 0 1 1 1 1 Talin, middle domain RRF PF01765.19 KIK57208.1 - 0.046 13.7 0.2 0.055 13.4 0.2 1.1 1 0 0 1 1 1 0 Ribosome recycling factor OGFr_N PF04664.13 KIK57209.1 - 4.6e-60 202.7 0.6 6.1e-60 202.3 0.6 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region YacG PF03884.14 KIK57210.1 - 0.12 12.1 0.7 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Ecl1 PF12855.7 KIK57210.1 - 0.46 11.6 52.6 1.6 9.8 0.1 3.5 2 1 1 3 3 3 0 ECL1/2/3 zinc binding proteins TMEM171 PF15471.6 KIK57210.1 - 0.94 8.4 3.6 1.7 7.6 3.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Methyltransf_3 PF01596.17 KIK57212.1 - 3.1e-39 134.4 0.0 3.7e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIK57212.1 - 1.6e-15 58.1 0.0 2.4e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57212.1 - 1.5e-08 34.6 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57212.1 - 3e-05 24.6 0.0 7.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KIK57212.1 - 5.7e-05 23.0 0.0 7.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KIK57212.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KIK57212.1 - 0.00089 19.9 0.0 0.0023 18.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIK57212.1 - 0.0056 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GCD14 PF08704.10 KIK57212.1 - 0.037 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RasGEF PF00617.19 KIK57213.1 - 9.4e-47 159.5 0.0 1.9e-46 158.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK57213.1 - 4.3e-19 68.7 0.0 9.3e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KIK57213.1 - 2.2e-12 46.6 0.0 4.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK57213.1 - 6.6e-12 44.9 0.3 1.7e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KIK57213.1 - 1.2e-11 44.0 0.0 2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Methyltransf_3 PF01596.17 KIK57214.1 - 3.6e-39 134.1 0.1 4.1e-39 134.0 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIK57214.1 - 1.4e-16 61.5 0.0 2.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57214.1 - 6.9e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57214.1 - 3.7e-07 30.8 0.0 7.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57214.1 - 6.8e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK57214.1 - 4.1e-06 26.7 0.0 5.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KIK57214.1 - 2.8e-05 23.5 0.0 4.5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 KIK57214.1 - 0.0005 19.8 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KIK57214.1 - 0.035 14.0 0.0 0.087 12.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.10 KIK57214.1 - 0.039 13.6 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TylF PF05711.11 KIK57214.1 - 0.071 12.4 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Peptidase_M55 PF04951.13 KIK57214.1 - 0.13 11.7 0.1 6.4 6.1 0.1 2.1 1 1 1 2 2 2 0 D-aminopeptidase Methyltransf_23 PF13489.6 KIK57214.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Glyco_hydro_10 PF00331.20 KIK57215.1 - 6.6e-103 344.2 0.0 8.2e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KIK57215.1 - 6.8e-15 54.7 11.6 6.8e-15 54.7 11.6 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain MA3 PF02847.17 KIK57216.1 - 1.9e-07 31.1 0.1 3.3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 MA3 domain FTR1 PF03239.14 KIK57219.1 - 1.3e-65 221.6 6.2 1.6e-65 221.3 6.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3169 PF11368.8 KIK57219.1 - 5.7 6.4 12.6 1 8.8 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF2085 PF09858.9 KIK57220.1 - 0.34 11.4 8.0 3.8 8.1 0.3 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) NACHT PF05729.12 KIK57221.1 - 9.7e-10 38.6 0.0 2.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK57221.1 - 1.7e-05 25.3 2.3 2.5e-05 24.7 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 KIK57221.1 - 0.013 15.9 0.0 0.041 14.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK57221.1 - 0.019 14.9 0.0 0.09 12.7 0.0 2.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea WD40 PF00400.32 KIK57221.1 - 0.049 14.5 8.4 7.7 7.6 0.1 5.6 6 0 0 6 6 6 0 WD domain, G-beta repeat PhoH PF02562.16 KIK57221.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.20 KIK57221.1 - 0.095 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 KIK57221.1 - 0.16 11.5 0.0 0.53 9.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK57221.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain EF_assoc_2 PF08356.12 KIK57222.1 - 9.2e-36 121.7 0.0 2e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KIK57222.1 - 1e-32 113.0 0.0 1.5e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 KIK57222.1 - 1.7e-30 104.4 0.7 4.1e-30 103.2 0.7 1.7 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 KIK57222.1 - 7.9e-20 71.3 0.0 6.3e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KIK57222.1 - 1.5e-10 39.9 1.3 0.00022 20.5 0.2 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.21 KIK57222.1 - 2.3e-10 40.2 0.0 0.00018 21.0 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.6 KIK57222.1 - 6.8e-10 38.1 0.4 0.00062 19.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIK57222.1 - 1.2e-09 38.5 0.3 0.0011 19.3 0.1 3.0 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIK57222.1 - 1.5e-08 33.7 2.4 0.0019 17.6 0.3 2.7 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KIK57222.1 - 5.8e-08 32.8 0.0 0.0024 17.9 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK57222.1 - 2.2e-07 31.2 0.1 0.011 16.0 0.0 3.2 2 2 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KIK57222.1 - 7.2e-07 29.7 0.1 0.038 14.4 0.1 2.5 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK57222.1 - 7.7e-06 25.9 0.2 0.089 12.7 0.0 3.9 4 0 0 4 4 4 1 RsgA GTPase AAA_18 PF13238.6 KIK57222.1 - 1.2e-05 25.9 0.0 0.031 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK57222.1 - 1.8e-05 25.0 0.0 0.076 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KIK57222.1 - 8e-05 22.8 0.3 0.14 12.2 0.0 2.9 2 1 1 3 3 3 1 Dynamin family AAA_7 PF12775.7 KIK57222.1 - 8.1e-05 22.2 0.0 0.045 13.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_29 PF13555.6 KIK57222.1 - 0.00011 21.9 0.0 0.097 12.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KIK57222.1 - 0.00012 22.4 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 KIK57222.1 - 0.00013 21.4 0.0 0.026 13.8 0.0 2.3 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 KIK57222.1 - 0.00015 21.3 0.1 0.22 10.9 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KIK57222.1 - 0.00016 22.2 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KIK57222.1 - 0.00016 22.1 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK57222.1 - 0.0002 21.1 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KIK57222.1 - 0.00032 20.6 0.0 0.71 9.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KIK57222.1 - 0.00047 20.5 0.0 0.81 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase EF-hand_10 PF14788.6 KIK57222.1 - 0.00077 19.3 1.8 0.093 12.6 0.1 2.5 2 0 0 2 2 2 1 EF hand DUF815 PF05673.13 KIK57222.1 - 0.00088 18.5 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) VirE PF05272.11 KIK57222.1 - 0.0012 18.6 0.0 2.1 8.0 0.0 2.7 3 0 0 3 3 2 1 Virulence-associated protein E ATP_bind_1 PF03029.17 KIK57222.1 - 0.0014 18.4 2.8 5.4 6.7 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 KIK57222.1 - 0.0018 18.1 0.0 0.081 12.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KIK57222.1 - 0.0019 17.4 0.0 0.64 9.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.9 KIK57222.1 - 0.0027 17.5 0.0 0.61 9.8 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KIK57222.1 - 0.0032 16.7 0.0 1.5 7.9 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit TsaE PF02367.17 KIK57222.1 - 0.0037 17.3 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 KIK57222.1 - 0.0044 16.9 0.0 0.82 9.6 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 MCM PF00493.23 KIK57222.1 - 0.0099 15.0 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KIK57222.1 - 0.01 15.2 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 KIK57222.1 - 0.011 15.8 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SPARC_Ca_bdg PF10591.9 KIK57222.1 - 0.011 16.1 1.5 1.3 9.3 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region cobW PF02492.19 KIK57222.1 - 0.011 15.4 0.1 0.93 9.1 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.21 KIK57222.1 - 0.013 15.2 0.2 0.39 10.4 0.1 2.8 2 1 1 3 3 3 0 Guanylate kinase AAA_25 PF13481.6 KIK57222.1 - 0.015 14.9 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain NOG1 PF06858.14 KIK57222.1 - 0.022 14.5 0.2 2.2 8.1 0.1 2.7 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Pox_A32 PF04665.12 KIK57222.1 - 0.024 14.1 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Sigma54_activat PF00158.26 KIK57222.1 - 0.03 14.0 0.0 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIK57222.1 - 0.031 14.3 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK57222.1 - 0.032 13.5 0.0 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KIK57222.1 - 0.042 12.8 0.0 6.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 KIK57222.1 - 0.049 14.1 0.2 8.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIK57222.1 - 0.05 13.0 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 KIK57222.1 - 0.06 13.2 0.1 2.2 8.1 0.1 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AIG1 PF04548.16 KIK57222.1 - 0.075 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_30 PF13604.6 KIK57222.1 - 0.079 12.7 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIK57222.1 - 0.085 12.5 0.0 5.7 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KIK57222.1 - 0.11 12.5 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 KIK57222.1 - 0.11 12.8 0.0 5.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4126 PF13548.6 KIK57222.1 - 0.57 9.8 2.8 0.29 10.8 0.6 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4126) VWA PF00092.28 KIK57223.1 - 6.8e-09 36.2 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK57223.1 - 4.9e-06 27.1 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 KIK57223.1 - 0.0019 18.1 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Tautomerase PF01361.21 KIK57223.1 - 0.081 12.9 0.0 0.31 11.0 0.0 2.0 1 0 0 1 1 1 0 Tautomerase enzyme Epimerase PF01370.21 KIK57224.1 - 1.6e-18 67.1 0.1 4.1e-18 65.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK57224.1 - 3.7e-16 59.0 0.0 5.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK57224.1 - 1.5e-13 51.1 0.0 2.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK57224.1 - 4.8e-06 26.3 0.1 9.1e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIK57224.1 - 1.4e-05 24.4 0.0 0.082 12.1 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK57224.1 - 5.9e-05 22.6 0.0 7.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK57224.1 - 0.0001 21.8 1.8 0.0039 16.7 0.1 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KIK57224.1 - 0.00042 19.5 0.0 0.0014 17.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIK57224.1 - 0.0028 16.8 0.1 0.0078 15.3 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KIK57225.1 - 6.4e-39 133.4 0.2 7.9e-39 133.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57225.1 - 1.8e-32 112.8 0.2 2.3e-32 112.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK57225.1 - 4.1e-14 52.9 0.0 6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK57225.1 - 0.0021 17.6 0.1 0.0062 16.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KIK57225.1 - 0.0036 17.0 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_3 PF01494.19 KIK57225.1 - 0.013 14.8 0.3 0.019 14.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KIK57225.1 - 0.022 14.7 0.8 0.035 14.0 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEAT_2 PF13646.6 KIK57226.1 - 7e-35 119.3 0.2 9.7e-16 57.9 0.0 3.7 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 KIK57226.1 - 1.5e-21 74.8 0.0 0.00076 19.9 0.1 5.3 5 0 0 5 5 5 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KIK57226.1 - 5.5e-12 44.9 0.5 0.31 11.4 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.23 KIK57226.1 - 2.4e-07 30.5 0.1 0.0039 17.2 0.0 3.3 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK57226.1 - 2.1e-05 24.9 1.8 0.28 11.8 0.1 5.1 4 2 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 KIK57226.1 - 0.013 15.6 0.0 0.34 10.9 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KIK57226.1 - 0.18 12.1 0.5 14 6.1 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Transp_cyt_pur PF02133.15 KIK57227.1 - 2.5e-27 95.8 34.0 4.1e-27 95.0 34.0 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.8 KIK57227.1 - 0.13 12.2 7.0 0.03 14.3 1.9 2.4 2 0 0 2 2 2 0 Conserved membrane protein YqhR GerA PF03323.13 KIK57227.1 - 5.9 5.2 5.1 9.5 4.6 5.1 1.4 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein p450 PF00067.22 KIK57228.1 - 3.1e-55 187.8 0.0 4.2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK57229.1 - 3.9e-56 190.7 0.0 5.5e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PP2C PF00481.21 KIK57230.1 - 0.0015 18.2 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Lipoxygenase PF00305.19 KIK57231.1 - 1.1e-47 163.0 0.2 6.4e-46 157.1 0.1 2.0 2 0 0 2 2 2 2 Lipoxygenase MMR_HSR1 PF01926.23 KIK57232.1 - 4.3e-07 30.0 0.1 4.3e-07 30.0 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK57232.1 - 8.3e-06 25.3 0.5 1.2e-05 24.7 0.5 1.5 1 1 0 1 1 1 1 AIG1 family SRPRB PF09439.10 KIK57232.1 - 0.00013 21.4 0.2 0.00013 21.4 0.2 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit CortBP2 PF09727.9 KIK57232.1 - 0.00046 20.2 11.8 0.0008 19.4 11.8 1.4 1 0 0 1 1 1 1 Cortactin-binding protein-2 RsgA_GTPase PF03193.16 KIK57232.1 - 0.0019 18.1 1.5 0.0036 17.2 0.2 2.0 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KIK57232.1 - 0.0027 17.0 0.1 0.0061 15.9 0.1 1.5 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 KIK57232.1 - 0.0031 17.8 0.6 0.0076 16.5 0.1 1.8 2 1 0 2 2 1 1 AAA domain FAM184 PF15665.5 KIK57232.1 - 0.0073 16.1 8.6 0.012 15.5 8.6 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B ABC_tran PF00005.27 KIK57232.1 - 0.018 15.5 0.7 0.44 11.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter KxDL PF10241.9 KIK57232.1 - 0.043 14.1 1.5 0.12 12.7 1.5 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF3862 PF12978.7 KIK57232.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) Golgin_A5 PF09787.9 KIK57232.1 - 0.048 13.1 9.1 0.071 12.6 9.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 KIK57232.1 - 0.1 12.6 10.3 0.54 10.3 10.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KIK57232.1 - 0.11 11.1 6.1 0.16 10.5 6.1 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KIK57232.1 - 0.11 11.3 9.0 0.16 10.8 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_18 PF13238.6 KIK57232.1 - 0.12 13.0 0.3 0.12 13.0 0.3 2.3 2 1 0 2 2 2 0 AAA domain HAUS6_N PF14661.6 KIK57232.1 - 0.12 11.9 5.7 0.2 11.2 5.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RNA_helicase PF00910.22 KIK57232.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF1043 PF06295.12 KIK57232.1 - 0.17 11.9 1.1 0.35 10.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Dynamin_N PF00350.23 KIK57232.1 - 0.17 11.9 6.3 0.71 9.9 0.1 3.1 2 1 1 3 3 3 0 Dynamin family CorA PF01544.18 KIK57232.1 - 0.17 11.1 2.9 0.28 10.5 2.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein dNK PF01712.19 KIK57232.1 - 0.2 11.5 2.5 0.61 9.9 0.1 2.5 3 0 0 3 3 3 0 Deoxynucleoside kinase Tup_N PF08581.10 KIK57232.1 - 0.22 11.8 7.8 8.8 6.7 7.8 2.4 1 1 0 1 1 1 0 Tup N-terminal DUF4446 PF14584.6 KIK57232.1 - 0.27 11.2 3.0 0.29 11.1 1.4 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF4446) FapA PF03961.13 KIK57232.1 - 0.34 9.5 6.3 0.48 9.0 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SWI-SNF_Ssr4 PF08549.10 KIK57232.1 - 0.45 9.1 7.3 0.63 8.6 7.3 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) UPF0242 PF06785.11 KIK57232.1 - 0.58 10.2 7.7 0.87 9.7 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 KIK57232.1 - 0.62 10.1 5.5 1.1 9.3 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 KIK57232.1 - 0.73 8.9 8.9 0.99 8.4 8.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KIK57232.1 - 0.83 9.4 8.7 1.4 8.7 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 KIK57232.1 - 1 8.5 4.8 1.4 8.1 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 KIK57232.1 - 2.1 9.0 5.8 5.9 7.6 5.8 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Vir_act_alpha_C PF10400.9 KIK57232.1 - 3.4 8.4 10.0 1.9 9.2 2.1 2.6 1 1 1 2 2 2 0 Virulence activator alpha C-term V_ATPase_I PF01496.19 KIK57232.1 - 5 4.9 5.8 6.4 4.6 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 KIK57232.1 - 5.3 7.1 7.3 7.4 6.6 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DivIC PF04977.15 KIK57232.1 - 6.9 6.5 8.9 1.9 8.3 2.1 2.6 1 1 1 2 2 2 0 Septum formation initiator MMR_HSR1 PF01926.23 KIK57233.1 - 2.8e-07 30.6 1.0 9.5e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK57233.1 - 1.2e-06 28.1 0.1 1.2e-06 28.1 0.1 2.3 2 1 1 3 3 3 1 AIG1 family SRPRB PF09439.10 KIK57233.1 - 0.00063 19.2 2.8 0.0012 18.3 0.1 2.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIK57233.1 - 0.0014 18.2 0.3 0.0029 17.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIK57233.1 - 0.0089 16.1 6.8 0.36 10.9 0.1 3.3 2 1 1 3 3 3 1 Dynamin family T2SSE PF00437.20 KIK57233.1 - 0.027 13.5 1.0 0.056 12.5 1.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein V_ATPase_I PF01496.19 KIK57233.1 - 0.046 11.7 3.0 0.059 11.3 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_24 PF13479.6 KIK57233.1 - 0.054 13.2 3.9 0.1 12.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain PEPCK_ATP PF01293.20 KIK57233.1 - 0.055 12.1 0.2 0.081 11.6 0.2 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Paramyx_P_V_C PF03210.13 KIK57233.1 - 0.1 12.4 1.4 0.25 11.1 0.7 1.9 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal G-alpha PF00503.20 KIK57233.1 - 0.17 11.0 3.4 3.2 6.8 0.1 2.8 3 0 0 3 3 3 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KIK57233.1 - 0.31 10.3 2.7 2.9 7.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mgr1 PF08602.10 KIK57233.1 - 0.33 9.7 1.9 0.51 9.1 1.9 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit AAA_18 PF13238.6 KIK57233.1 - 0.33 11.5 2.5 0.55 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.16 KIK57233.1 - 0.37 9.7 2.7 0.53 9.1 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAT PF03127.14 KIK57233.1 - 0.55 10.6 9.4 0.54 10.6 3.3 3.3 2 1 1 3 3 3 0 GAT domain YtxH PF12732.7 KIK57233.1 - 0.86 10.2 3.2 0.75 10.4 0.9 2.2 2 1 0 2 2 1 0 YtxH-like protein DUF2203 PF09969.9 KIK57233.1 - 1.4 9.6 8.2 4 8.2 5.5 2.9 3 1 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) Hpt PF01627.23 KIK57233.1 - 1.8 8.9 6.5 5.7 7.3 0.1 3.0 2 1 0 3 3 3 0 Hpt domain PCRF PF03462.18 KIK57233.1 - 2 8.2 9.0 2.7 7.8 6.9 2.1 2 0 0 2 2 2 0 PCRF domain FapA PF03961.13 KIK57233.1 - 2.4 6.7 4.5 2 7.0 3.4 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 KIK57233.1 - 2.9 8.7 7.4 30 5.4 5.2 2.9 3 0 0 3 3 3 0 Occludin homology domain BPS1 PF05633.11 KIK57233.1 - 3 6.8 9.4 4.4 6.2 9.4 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related RsgA_GTPase PF03193.16 KIK57233.1 - 6.9 6.5 5.9 2.7 7.9 1.6 2.4 2 1 0 2 2 2 0 RsgA GTPase TMPIT PF07851.13 KIK57233.1 - 8.5 5.5 5.9 14 4.8 5.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein MMR_HSR1 PF01926.23 KIK57234.1 - 8.9e-09 35.4 0.1 8.9e-09 35.4 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK57234.1 - 1.5e-06 27.7 0.3 1.5e-06 27.7 0.3 1.9 1 1 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 KIK57234.1 - 3.5e-05 24.4 2.0 0.00021 21.8 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Septin PF00735.18 KIK57234.1 - 3.7e-05 23.2 0.2 9.9e-05 21.7 0.2 1.8 1 0 0 1 1 1 1 Septin Macoilin PF09726.9 KIK57234.1 - 0.0002 20.1 8.8 0.00021 20.0 8.8 1.2 1 0 0 1 1 1 1 Macoilin family SRPRB PF09439.10 KIK57234.1 - 0.00031 20.2 0.1 0.00031 20.2 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KIK57234.1 - 0.00043 20.2 0.9 0.00043 20.2 0.9 2.6 2 2 1 3 3 3 1 RsgA GTPase IIGP PF05049.13 KIK57234.1 - 0.0046 16.1 0.2 0.013 14.6 0.1 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KIK57234.1 - 0.011 15.9 0.7 0.011 15.9 0.7 3.6 2 2 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 KIK57234.1 - 0.011 15.2 0.6 0.026 14.1 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 KIK57234.1 - 0.044 13.3 4.5 0.11 12.1 0.4 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SMC_N PF02463.19 KIK57234.1 - 0.051 13.0 5.9 3.4 7.0 0.0 2.5 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KIK57234.1 - 0.061 13.4 1.2 0.061 13.4 1.2 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 KIK57234.1 - 0.19 11.5 0.1 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 KIK57234.1 - 0.26 9.9 13.2 0.42 9.2 10.5 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK57234.1 - 0.34 10.8 2.3 19 5.1 0.1 2.6 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.18 KIK57234.1 - 0.35 10.2 4.6 1.8 7.8 0.0 3.2 2 1 2 4 4 4 0 FtsK/SpoIIIE family Takusan PF04822.13 KIK57234.1 - 0.4 10.6 10.1 1.2 9.0 9.6 2.2 1 1 0 1 1 1 0 Takusan AAA_24 PF13479.6 KIK57234.1 - 0.76 9.5 4.5 1.1 8.9 0.4 2.8 1 1 0 2 2 2 0 AAA domain DUF3450 PF11932.8 KIK57234.1 - 0.93 8.7 17.0 1.7 7.9 17.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS6_N PF14661.6 KIK57234.1 - 1.5 8.3 17.7 0.02 14.5 10.2 1.6 2 0 0 2 2 1 0 HAUS augmin-like complex subunit 6 N-terminus G-alpha PF00503.20 KIK57234.1 - 4.7 6.3 10.9 0.16 11.1 0.1 2.5 1 1 0 2 2 2 0 G-protein alpha subunit Exonuc_VII_L PF02601.15 KIK57234.1 - 4.9 6.6 11.4 7.7 6.0 11.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GvpL_GvpF PF06386.11 KIK57234.1 - 5.6 6.8 14.9 10 6.0 14.9 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PP2C PF00481.21 KIK57235.1 - 8.6e-35 120.6 0.0 4e-32 111.9 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK57235.1 - 0.00018 21.2 0.0 0.00042 20.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Methyltr_RsmB-F PF01189.17 KIK57235.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ank_3 PF13606.6 KIK57236.1 - 0.14 12.8 0.3 2.6 8.9 0.1 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KIK57236.1 - 0.2 12.0 0.7 2.1 8.8 0.0 3.0 4 0 0 4 4 4 0 Ankyrin repeats (many copies) NAD_binding_4 PF07993.12 KIK57239.1 - 5.7e-30 104.3 0.0 1.2e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK57239.1 - 1.8e-26 92.8 1.0 1.9e-26 92.6 0.1 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIK57239.1 - 2.7e-06 27.0 0.0 1.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK57239.1 - 0.0088 16.4 0.0 0.041 14.2 0.0 2.2 2 1 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KIK57240.1 - 2.5e-30 105.5 0.0 4e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK57240.1 - 8.2e-27 93.8 0.0 1.8e-26 92.8 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIK57240.1 - 2.4e-05 23.9 0.0 0.00023 20.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK57240.1 - 0.0007 19.9 0.2 0.0036 17.6 0.1 2.4 3 1 0 3 3 3 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KIK57240.1 - 0.0024 17.8 0.0 0.76 9.6 0.0 3.9 4 1 0 4 4 4 1 NAD(P)H-binding AAA PF00004.29 KIK57242.1 - 7.3e-40 136.5 0.0 1.5e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK57242.1 - 7e-21 73.9 0.2 1.4e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIK57242.1 - 1.8e-09 37.3 0.2 4.2e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK57242.1 - 2.7e-05 24.6 0.5 0.008 16.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KIK57242.1 - 0.00048 20.1 0.1 0.0026 17.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK57242.1 - 0.00059 20.0 0.1 0.0077 16.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK57242.1 - 0.0006 20.1 0.5 0.046 14.0 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK57242.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK57242.1 - 0.0021 17.9 0.2 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIK57242.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KIK57242.1 - 0.004 16.6 0.1 0.075 12.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KIK57242.1 - 0.019 14.3 0.2 0.071 12.5 0.1 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIK57242.1 - 0.036 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein JIP_LZII PF16471.5 KIK57242.1 - 1.1 9.4 5.1 0.32 11.2 1.5 2.0 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II XhlA PF10779.9 KIK57242.1 - 2.4 8.4 5.7 45 4.4 4.1 2.6 2 0 0 2 2 2 0 Haemolysin XhlA NuA4 PF09340.10 KIK57243.1 - 1.2e-22 79.6 0.2 1.2e-22 79.6 0.2 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Enkurin PF13864.6 KIK57243.1 - 0.03 14.8 1.8 0.39 11.2 0.1 2.4 2 1 0 2 2 2 0 Calmodulin-binding KH_6 PF15985.5 KIK57246.1 - 7.7e-15 55.0 0.1 1.7e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KIK57246.1 - 3.6e-14 52.4 0.7 7.6e-14 51.4 0.7 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Mod_r PF07200.13 KIK57247.1 - 1e-43 148.9 5.4 1.2e-43 148.7 5.4 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF349 PF03993.12 KIK57247.1 - 0.023 15.0 1.8 0.2 12.0 1.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) APG6_N PF17675.1 KIK57247.1 - 0.086 13.4 3.8 0.19 12.3 3.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 KIK57247.1 - 0.14 12.3 3.1 0.32 11.1 0.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 KIK57247.1 - 0.15 12.5 2.3 0.29 11.6 2.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF3244 PF11589.8 KIK57250.1 - 0.14 12.2 1.2 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) CbiQ PF02361.16 KIK57253.1 - 7.5 6.1 24.5 4.9 6.7 15.4 3.1 2 1 1 3 3 3 0 Cobalt transport protein Na_Ca_ex PF01699.24 KIK57255.1 - 1.8e-35 122.1 42.1 2.3e-18 66.6 13.9 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EptA_B_N PF08019.12 KIK57255.1 - 2.8 7.8 0.0 2.8 7.8 0.0 4.8 4 2 3 7 7 7 0 Phosphoethanolamine transferase EptA/EptB DUF5134 PF17197.4 KIK57258.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) p450 PF00067.22 KIK57259.1 - 7e-80 269.0 0.0 8.8e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.12 KIK57260.1 - 1.2e-29 103.3 0.0 2.2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK57260.1 - 1.9e-24 86.0 0.0 3.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK57260.1 - 3.7e-07 29.8 0.0 2.3e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK57260.1 - 1.4e-05 25.3 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GH3 PF03321.13 KIK57260.1 - 0.037 12.9 0.0 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 GH3 auxin-responsive promoter NAD_binding_10 PF13460.6 KIK57260.1 - 0.11 12.3 0.0 3.3 7.6 0.0 2.8 2 1 0 2 2 2 0 NAD(P)H-binding DRMBL PF07522.14 KIK57261.1 - 3.8e-06 27.0 0.0 1.7e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KIK57261.1 - 0.0027 17.3 0.7 0.012 15.2 0.7 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_S9 PF00326.21 KIK57262.1 - 6.7e-47 159.7 0.8 1.2e-46 158.9 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KIK57262.1 - 0.00024 19.9 0.0 0.037 12.7 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) RL10P_insert PF17777.1 KIK57263.1 - 2.1e-21 75.7 0.0 3.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KIK57263.1 - 2.4e-19 69.3 0.0 3.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF5341 PF17276.2 KIK57263.1 - 0.086 13.0 0.2 0.2 11.8 0.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5341) RRF PF01765.19 KIK57263.1 - 0.1 12.5 0.5 0.2 11.6 0.2 1.7 2 0 0 2 2 2 0 Ribosome recycling factor NACHT PF05729.12 KIK57264.1 - 8.8e-11 42.0 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK57264.1 - 0.0002 21.8 1.1 0.0035 17.8 0.2 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KIK57264.1 - 0.026 14.1 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KIK57264.1 - 0.04 14.8 5.4 1.7e+02 3.3 0.0 6.3 5 0 0 5 5 5 0 WD domain, G-beta repeat ATPase_2 PF01637.18 KIK57264.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK57264.1 - 0.17 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 KIK57264.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 KIK57264.1 - 0.19 11.0 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain MBOAT_2 PF13813.6 KIK57268.1 - 4.3e-13 49.4 2.9 4.3e-13 49.4 2.9 2.3 3 1 0 3 3 3 1 Membrane bound O-acyl transferase family UQ_con PF00179.26 KIK57269.1 - 5.9e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 KIK57270.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Zn_clus PF00172.18 KIK57271.1 - 4.5e-08 33.1 8.2 8.7e-08 32.2 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 KIK57272.1 - 2.7e-08 33.6 0.0 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain HEAT_EZ PF13513.6 KIK57273.1 - 3.4e-17 62.6 17.7 3.8e-08 33.7 0.1 7.7 6 1 2 8 8 8 4 HEAT-like repeat HEAT PF02985.22 KIK57273.1 - 4.2e-13 48.3 6.2 6e-05 23.0 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KIK57273.1 - 2.6e-12 47.1 0.4 3e-05 24.5 0.0 4.0 2 1 2 4 4 4 2 Vacuolar 14 Fab1-binding region Importin_rep_4 PF18808.1 KIK57273.1 - 3.6e-10 40.0 0.2 1.7e-08 34.6 0.0 3.6 3 1 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 KIK57273.1 - 1e-09 38.7 2.8 2.4e-05 24.7 0.0 5.9 4 1 2 6 6 6 2 HEAT repeats RIX1 PF08167.12 KIK57273.1 - 5.7e-08 32.7 3.5 3.6e-05 23.6 0.0 3.6 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 KIK57273.1 - 1.3e-06 28.4 0.1 0.28 11.1 0.0 4.6 3 1 1 4 4 4 3 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KIK57273.1 - 2.2e-06 26.6 0.1 1.5e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KIK57273.1 - 4.6e-06 26.8 0.1 3.4e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KIK57273.1 - 0.0077 15.4 5.3 0.094 11.8 0.1 3.7 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KIK57273.1 - 0.029 14.5 0.2 5.4 7.2 0.0 3.6 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 ACDC PF14733.6 KIK57273.1 - 0.033 14.5 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AP2-coincident C-terminal Cnd3 PF12719.7 KIK57273.1 - 1.5 8.0 7.3 0.94 8.6 0.0 3.6 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Ribosomal_S17e PF00833.18 KIK57274.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal S17 Adaptin_binding PF10199.9 KIK57277.1 - 2.5e-05 24.9 18.4 2.9e-05 24.7 10.8 3.7 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Methyltransf_25 PF13649.6 KIK57278.1 - 6.3e-15 55.7 0.0 1.6e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57278.1 - 4.9e-10 39.9 0.0 1.3e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57278.1 - 3.8e-08 33.4 0.0 7.3e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57278.1 - 2.9e-07 30.1 0.0 4.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK57278.1 - 2.1e-06 27.6 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK57278.1 - 9.7e-05 23.1 0.0 0.00039 21.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK57278.1 - 0.0005 19.4 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KIK57278.1 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KIK57278.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ribosomal_60s PF00428.19 KIK57278.1 - 1.3 9.6 5.4 3.7 8.2 5.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein SRF-TF PF00319.18 KIK57279.1 - 7.2e-21 73.4 0.1 1.1e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) WD40 PF00400.32 KIK57280.1 - 2.8e-14 53.2 1.5 0.0021 18.8 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57280.1 - 7.3e-06 26.2 0.0 5.9 7.3 0.0 5.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK57280.1 - 0.013 14.5 0.0 0.56 9.1 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK57280.1 - 0.035 12.9 0.5 0.82 8.3 0.5 2.5 1 1 0 1 1 1 0 Nup133 N terminal like NicO PF03824.16 KIK57282.1 - 3.3e-50 171.0 0.2 3.3e-50 171.0 0.2 2.7 2 1 0 2 2 2 1 High-affinity nickel-transport protein Phage_holin_2_4 PF16082.5 KIK57282.1 - 0.087 12.6 5.4 5.6 6.8 3.1 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like RTA1 PF04479.13 KIK57285.1 - 3.3e-51 173.8 8.6 3.3e-51 173.8 8.6 1.3 2 0 0 2 2 2 1 RTA1 like protein CDC37_N PF03234.14 KIK57286.1 - 6e-41 140.4 1.4 7.7e-41 140.0 0.2 1.8 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KIK57286.1 - 4.7e-33 113.6 0.1 1.2e-32 112.4 0.0 1.7 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KIK57286.1 - 3.7e-17 62.3 0.0 3.7e-17 62.3 0.0 2.5 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF3439 PF11921.8 KIK57286.1 - 0.18 11.7 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_trans_2_3 PF13632.6 KIK57287.1 - 1.1e-48 165.7 0.2 1.1e-48 165.7 0.2 2.5 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK57287.1 - 0.0002 21.3 0.2 0.00051 20.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK57287.1 - 0.032 14.1 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK57287.1 - 0.089 12.3 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 21 Mito_carr PF00153.27 KIK57288.1 - 9.1e-41 137.7 5.0 6.7e-16 58.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KIK57289.1 - 3.2e-64 216.8 0.0 4.4e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57289.1 - 8.5e-35 120.3 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIK57289.1 - 6.9e-15 55.2 0.1 1.5e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK57289.1 - 1.7e-06 28.2 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KIK57289.1 - 7.7e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK57289.1 - 0.00018 20.9 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK57289.1 - 0.0014 17.5 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIK57289.1 - 0.0035 16.3 0.0 0.0053 15.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK57289.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABM PF03992.16 KIK57290.1 - 0.0016 18.6 0.0 0.028 14.6 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 KIK57290.1 - 0.059 13.6 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 Dabb PF07876.12 KIK57290.1 - 0.065 13.9 0.1 0.28 11.8 0.0 1.9 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain ABM PF03992.16 KIK57291.1 - 3.2e-07 30.4 0.3 0.001 19.2 0.1 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase F-box-like PF12937.7 KIK57293.1 - 9.4e-12 44.6 0.0 2.7e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK57293.1 - 0.0017 18.2 0.0 0.0088 15.9 0.0 2.2 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KIK57293.1 - 0.003 17.9 11.0 0.36 11.3 0.7 6.0 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 KIK57293.1 - 0.004 17.2 8.6 0.2 11.9 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK57293.1 - 0.026 14.4 5.5 2.6 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 KIK57293.1 - 1.6 8.6 7.9 1.7 8.4 0.2 3.9 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 KIK57293.1 - 4.3 7.6 5.2 5.1 7.4 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Acyl-CoA_dh_1 PF00441.24 KIK57294.1 - 3.2e-17 63.1 0.2 3.5e-17 63.0 0.2 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK57294.1 - 6.1e-09 36.3 0.3 6.4e-09 36.2 0.3 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1327 PF07041.11 KIK57294.1 - 0.16 12.0 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) Acyl-CoA_dh_N PF02771.16 KIK57295.1 - 1.3e-09 38.7 0.0 2.7e-09 37.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIK57295.1 - 0.00014 22.0 0.0 0.00041 20.5 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KIK57297.1 - 1.2e-23 84.0 1.0 1.6e-23 83.6 1.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK57297.1 - 2.4e-10 40.8 1.4 2.4e-10 40.8 1.4 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain RST PF12174.8 KIK57298.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Acyl-CoA_dh_1 PF00441.24 KIK57301.1 - 6.9e-42 143.2 1.8 9.9e-42 142.7 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIK57301.1 - 4e-30 104.8 0.8 4.8e-28 98.1 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIK57301.1 - 3.6e-21 75.2 0.0 8.4e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK57301.1 - 3.3e-18 66.3 0.2 4.8e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KIK57301.1 - 0.025 15.1 0.0 0.07 13.7 0.0 1.8 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ATP-synt_S1 PF05827.12 KIK57302.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Transposase_mut PF00872.18 KIK57304.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family G-patch PF01585.23 KIK57305.1 - 9.1e-06 25.5 0.1 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 1 G-patch domain vATP-synt_AC39 PF01992.16 KIK57306.1 - 4.1e-118 394.7 0.1 4.6e-118 394.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GATase_2 PF00310.21 KIK57306.1 - 0.025 13.3 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II RTA1 PF04479.13 KIK57307.1 - 3.6e-55 186.8 1.9 3.6e-55 186.8 1.9 1.3 2 0 0 2 2 2 1 RTA1 like protein KleE PF17394.2 KIK57307.1 - 0.67 10.2 6.0 0.61 10.3 2.3 2.4 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein DUF903 PF06004.12 KIK57308.1 - 0.063 13.2 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) VIR_N PF15912.5 KIK57309.1 - 1 8.9 11.4 1.3 8.5 11.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF903 PF06004.12 KIK57310.1 - 0.032 14.1 0.5 0.055 13.4 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) zf-RING_5 PF14634.6 KIK57311.1 - 6.7e-08 32.4 8.6 1e-07 31.8 8.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK57311.1 - 3.4e-07 30.0 8.0 7.1e-07 29.0 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK57311.1 - 9.6e-07 28.7 4.9 3.2e-06 27.1 4.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK57311.1 - 5.1e-06 26.3 9.2 8.8e-06 25.5 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK57311.1 - 2.8e-05 24.4 10.5 4.4e-05 23.7 10.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK57311.1 - 0.005 16.7 10.4 0.0086 15.9 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK57311.1 - 0.015 15.1 11.2 0.032 14.1 11.2 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KIK57311.1 - 0.085 12.2 0.1 0.085 12.2 0.1 2.4 3 0 0 3 3 3 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KIK57311.1 - 0.087 13.0 11.4 0.18 12.0 11.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KIK57311.1 - 0.095 12.8 2.4 0.21 11.7 2.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger HR1 PF02185.16 KIK57311.1 - 0.63 10.2 3.5 5.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Hr1 repeat DUF641 PF04859.12 KIK57311.1 - 0.89 9.9 3.8 2.8 8.3 3.8 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KIK57311.1 - 1.6 8.0 4.7 3.3 7.0 4.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_4 PF14570.6 KIK57311.1 - 2.6 7.9 12.8 4.1 7.3 12.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KIK57311.1 - 2.7 8.1 9.4 4.9 7.3 9.4 1.5 1 0 0 1 1 1 0 Zinc-finger ATG16 PF08614.11 KIK57311.1 - 9.9 6.3 10.7 31 4.7 8.2 3.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.21 KIK57312.1 - 3.5e-30 103.6 0.7 6.1e-30 102.9 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIK57312.1 - 4.6e-25 87.5 0.0 7.1e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain zf-RING_5 PF14634.6 KIK57314.1 - 5.4e-07 29.5 9.7 9.7e-07 28.6 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK57314.1 - 9.7e-07 29.0 10.4 1.8e-06 28.2 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK57314.1 - 3.1e-06 27.0 9.3 5.8e-06 26.1 9.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIK57314.1 - 1.1e-05 25.2 8.5 1.9e-05 24.4 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KIK57314.1 - 4e-05 23.3 5.6 6.8e-05 22.6 5.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KIK57314.1 - 4.6e-05 23.4 6.4 4.6e-05 23.4 6.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK57314.1 - 0.00013 21.7 10.4 0.00029 20.6 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK57314.1 - 0.00023 20.9 9.8 0.00047 20.0 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK57314.1 - 0.0016 18.5 10.1 0.0049 17.0 10.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KIK57314.1 - 0.0028 17.1 7.7 0.014 14.8 7.7 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.6 KIK57314.1 - 0.0046 16.8 3.1 0.0084 16.0 3.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIK57314.1 - 0.028 14.7 6.9 0.063 13.6 6.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 KIK57314.1 - 0.075 13.1 4.0 0.16 12.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FTA4 PF13093.6 KIK57314.1 - 0.17 11.8 4.0 0.29 11.0 3.8 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 KIK57314.1 - 0.55 10.8 7.0 0.71 10.4 6.7 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Sec61_beta PF03911.16 KIK57315.1 - 1.1e-17 63.8 0.6 1.4e-17 63.4 0.6 1.2 1 0 0 1 1 1 1 Sec61beta family DUF3808 PF10300.9 KIK57316.1 - 1.4e-73 248.3 0.1 1.8e-73 247.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KIK57316.1 - 0.00048 20.7 0.4 3 8.6 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK57316.1 - 0.01 15.9 8.7 0.12 12.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK57316.1 - 0.063 13.1 0.1 12 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK57316.1 - 0.44 11.5 3.7 13 6.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK57316.1 - 0.48 11.2 4.4 49 4.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SET PF00856.28 KIK57317.1 - 1.3e-14 54.9 0.0 2.2e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 SET domain FIST_C PF10442.9 KIK57317.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 FIST C domain SET PF00856.28 KIK57318.1 - 0.091 13.1 0.0 0.091 13.1 0.0 1.1 1 0 0 1 1 1 0 SET domain SPA PF08616.10 KIK57320.1 - 0.098 12.6 3.5 0.065 13.2 0.7 2.0 2 0 0 2 2 2 0 Stabilization of polarity axis CaiF_GrlA PF07180.11 KIK57322.1 - 0.038 14.0 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator zf-RING_5 PF14634.6 KIK57325.1 - 1.7e-09 37.5 6.3 3.3e-09 36.5 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK57325.1 - 4.7e-08 33.2 9.2 9.2e-08 32.3 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK57325.1 - 2.7e-07 30.3 6.2 6e-07 29.2 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK57325.1 - 2.9e-07 30.3 6.7 6e-07 29.2 6.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK57325.1 - 6e-07 29.4 3.0 6e-07 29.4 3.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK57325.1 - 8.2e-06 25.6 8.4 1.9e-05 24.4 8.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK57325.1 - 0.00014 21.7 7.3 0.00033 20.5 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK57325.1 - 0.00067 19.8 7.2 0.007 16.5 6.3 2.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING FYVE PF01363.21 KIK57325.1 - 0.0028 17.8 3.9 0.016 15.3 4.2 2.0 1 1 0 1 1 1 1 FYVE zinc finger zf-RING_4 PF14570.6 KIK57325.1 - 0.012 15.4 8.2 0.023 14.5 8.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 KIK57325.1 - 0.022 14.1 12.1 0.14 11.5 12.1 2.2 1 1 0 1 1 1 0 Rtf2 RING-finger Exonuc_VII_L PF02601.15 KIK57325.1 - 0.026 14.1 4.1 0.031 13.9 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_6 PF14835.6 KIK57325.1 - 0.034 14.0 5.6 0.12 12.3 5.6 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KIK57325.1 - 0.17 12.0 2.7 0.33 11.1 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 KIK57325.1 - 0.72 10.2 6.5 2.1 8.7 6.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C2HC5 PF06221.13 KIK57325.1 - 0.8 9.7 4.4 0.17 11.9 0.6 1.8 2 0 0 2 2 1 0 Putative zinc finger motif, C2HC5-type Bacillus_HBL PF05791.11 KIK57325.1 - 0.95 9.3 7.7 1.1 9.0 6.6 1.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FapA PF03961.13 KIK57325.1 - 1.5 7.4 6.5 1.9 7.0 6.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_11 PF17123.5 KIK57325.1 - 4.7 7.1 8.6 0.41 10.4 2.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger FYDLN_acid PF09538.10 KIK57325.1 - 6.5 7.5 6.5 0.91 10.2 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 KIK57325.1 - 7.4 6.7 9.8 2.5 8.2 6.5 2.0 2 1 0 2 2 2 0 Double zinc ribbon DUF4407 PF14362.6 KIK57325.1 - 8.4 5.6 11.7 3.4 7.0 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Zn_clus PF00172.18 KIK57326.1 - 4.3e-07 30.0 8.8 7.7e-07 29.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK57326.1 - 1.4e-05 24.3 0.1 1.4e-05 24.3 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sacchrp_dh_C PF16653.5 KIK57327.1 - 3e-64 217.7 0.0 4.9e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KIK57327.1 - 7.9e-17 61.7 0.3 1.6e-16 60.7 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 KIK57327.1 - 6.7e-15 55.6 0.0 8.9e-14 52.0 0.0 2.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIK57327.1 - 0.037 13.3 0.0 2.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_10 PF13374.6 KIK57328.1 - 1.4e-178 574.8 41.2 7.1e-12 44.8 0.0 20.0 20 0 0 20 20 20 19 Tetratricopeptide repeat TPR_12 PF13424.6 KIK57328.1 - 7.3e-147 478.0 87.5 2.8e-14 53.2 0.1 14.7 2 2 14 17 17 17 17 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK57328.1 - 7.7e-39 134.0 26.2 1e-09 38.2 1.0 5.3 1 1 4 5 5 5 5 MalT-like TPR region TPR_7 PF13176.6 KIK57328.1 - 9.7e-26 87.9 43.3 0.013 15.5 0.0 18.1 20 0 0 20 20 18 6 Tetratricopeptide repeat TPR_4 PF07721.14 KIK57328.1 - 7.6e-21 72.6 10.6 0.19 12.5 0.0 14.5 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK57328.1 - 3.3e-19 67.8 38.1 2.1 8.9 0.1 16.5 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK57328.1 - 4.3e-15 54.6 36.3 0.043 14.0 0.0 15.0 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK57328.1 - 9.9e-14 50.3 37.5 0.012 15.7 0.2 15.5 17 0 0 17 17 16 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK57328.1 - 1.7e-12 46.6 43.6 0.6 10.0 0.1 16.2 18 0 0 18 18 18 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK57328.1 - 6.1e-11 42.7 34.4 0.091 13.3 0.1 11.7 5 3 9 14 14 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 KIK57328.1 - 5.3e-08 33.0 21.3 7.1 7.7 0.0 12.5 12 2 1 13 13 12 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK57328.1 - 3e-06 27.8 7.6 0.87 10.3 0.3 8.3 8 1 1 9 9 7 1 Tetratricopeptide repeat DUF4919 PF16266.5 KIK57328.1 - 4.8e-06 26.6 7.0 0.35 10.8 0.1 7.3 5 3 5 10 10 10 1 Domain of unknown function (DUF4919) DHDPS PF00701.22 KIK57328.1 - 0.0012 17.6 9.0 2.2 6.9 0.1 7.5 3 3 7 11 11 11 1 Dihydrodipicolinate synthetase family Trans_reg_C PF00486.28 KIK57328.1 - 0.0013 18.8 0.0 33 4.7 0.0 5.4 6 1 1 7 7 6 0 Transcriptional regulatory protein, C terminal Meckelin PF09773.9 KIK57328.1 - 0.0021 16.3 9.2 0.19 9.8 0.5 3.9 4 1 0 4 4 4 2 Meckelin (Transmembrane protein 67) MCPVI PF02993.14 KIK57328.1 - 0.014 15.3 7.3 1.4e+02 2.2 0.0 7.5 4 2 3 9 9 9 0 Minor capsid protein VI Pterin_4a PF01329.19 KIK57328.1 - 0.018 15.2 2.4 15 5.9 0.0 5.6 6 1 1 7 7 6 0 Pterin 4 alpha carbinolamine dehydratase Dynactin_p22 PF07426.11 KIK57328.1 - 0.018 14.9 0.2 0.018 14.9 0.2 4.3 4 1 1 5 5 5 0 Dynactin subunit p22 ATPgrasp_ST PF14397.6 KIK57328.1 - 0.028 13.7 2.8 5.2 6.2 0.0 5.4 4 2 3 7 7 7 0 Sugar-transfer associated ATP-grasp SAA PF00277.18 KIK57328.1 - 0.029 14.8 0.8 1e+02 3.4 0.0 5.0 6 1 0 6 6 4 0 Serum amyloid A protein DUF3288 PF11691.8 KIK57328.1 - 0.09 12.8 0.1 4.8 7.3 0.0 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF3288) cwf21 PF08312.12 KIK57328.1 - 0.66 10.2 14.9 37 4.6 2.5 6.6 6 1 1 7 7 6 0 cwf21 domain Dicer_dimer PF03368.14 KIK57328.1 - 0.93 9.7 18.9 4.6 7.5 0.2 7.6 9 1 0 9 9 9 0 Dicer dimerisation domain TPR_6 PF13174.6 KIK57328.1 - 1.7 9.4 9.8 38 5.2 0.0 6.2 6 0 0 6 6 4 0 Tetratricopeptide repeat PARP PF00644.20 KIK57329.1 - 9e-14 51.5 1.8 7.1e-11 42.1 0.3 3.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF2024 PF09630.10 KIK57329.1 - 6.9 6.6 5.5 11 5.9 0.6 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF2024) YyzF PF14116.6 KIK57329.1 - 7.6 6.6 7.4 45 4.2 0.1 3.7 4 0 0 4 4 4 0 YyzF-like protein PARP PF00644.20 KIK57330.1 - 3.3e-14 52.9 0.9 4e-11 42.9 0.0 3.0 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 KIK57331.1 - 9.3e-31 107.2 0.1 1e-30 107.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 KIK57331.1 - 0.046 13.5 0.0 0.36 10.6 0.0 2.0 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 HTH_31 PF13560.6 KIK57332.1 - 4.2e-08 33.4 0.0 5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIK57332.1 - 2.7e-05 24.2 0.0 3.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIK57332.1 - 0.00062 19.7 0.0 0.00078 19.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIK57332.1 - 0.0028 18.0 0.0 0.0034 17.8 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_AsnC-type PF13404.6 KIK57332.1 - 0.0051 16.6 0.2 0.047 13.5 0.1 2.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Toxin_16 PF07945.11 KIK57332.1 - 0.01 15.7 0.5 0.023 14.5 0.5 1.6 1 0 0 1 1 1 0 Janus-atracotoxin HTH_24 PF13412.6 KIK57332.1 - 0.021 14.4 0.1 0.044 13.4 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_35 PF13693.6 KIK57332.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KIK57332.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIK57332.1 - 0.17 11.4 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 NUDIX PF00293.28 KIK57333.1 - 4.7e-10 39.6 0.0 3.5e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain WhiA_N PF10298.9 KIK57335.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain DLH PF01738.18 KIK57336.1 - 3.3e-15 56.2 0.0 1.5e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family ABC_membrane PF00664.23 KIK57337.1 - 2.9e-56 191.1 33.2 4.8e-32 111.7 16.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK57337.1 - 9.3e-56 188.1 0.2 1.7e-31 109.6 0.1 2.7 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KIK57337.1 - 7.7e-09 35.6 1.0 0.0023 18.0 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KIK57337.1 - 1e-07 31.7 6.2 0.02 14.4 0.1 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK57337.1 - 7.5e-07 28.8 0.1 0.064 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK57337.1 - 1.4e-06 28.4 1.3 0.068 13.0 0.1 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIK57337.1 - 2.4e-06 28.0 1.5 0.011 16.1 0.3 3.1 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK57337.1 - 7.2e-06 26.0 2.5 0.13 12.1 0.1 3.0 2 1 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KIK57337.1 - 0.0001 21.6 1.4 0.2 10.9 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.18 KIK57337.1 - 0.00079 18.8 0.1 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.6 KIK57337.1 - 0.001 18.9 2.8 0.39 10.4 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KIK57337.1 - 0.0013 19.3 12.1 0.15 12.5 0.1 3.6 3 1 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KIK57337.1 - 0.0019 17.7 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 KIK57337.1 - 0.0022 17.9 0.1 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 KIK57337.1 - 0.0025 17.0 0.9 0.29 10.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KIK57337.1 - 0.003 17.6 11.2 0.06 13.4 0.5 3.7 3 0 0 3 3 3 2 Dynamin family AAA_22 PF13401.6 KIK57337.1 - 0.0053 17.0 1.3 4.6 7.5 0.2 3.2 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK57337.1 - 0.0071 16.5 2.6 0.64 10.1 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KIK57337.1 - 0.016 14.3 0.0 22 4.0 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 KIK57337.1 - 0.018 14.3 0.0 2 7.5 0.0 2.6 3 0 0 3 3 3 0 KAP family P-loop domain AAA_30 PF13604.6 KIK57337.1 - 0.02 14.6 3.0 2.6 7.7 0.0 3.2 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 KIK57337.1 - 0.024 15.0 0.1 21 5.6 0.0 3.4 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 KIK57337.1 - 0.032 13.4 1.0 10 5.2 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.9 KIK57337.1 - 0.035 13.0 1.1 2.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 KIK57337.1 - 0.037 13.6 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK57337.1 - 0.04 13.5 0.4 5.1 6.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KIK57337.1 - 0.045 13.7 0.2 7 6.6 0.0 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 KIK57337.1 - 0.047 13.3 0.5 7.3 6.2 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KIK57337.1 - 0.056 13.7 5.3 3.4 7.9 0.1 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KIK57337.1 - 0.073 13.6 0.0 18 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KIK57337.1 - 0.088 12.8 0.2 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KIK57337.1 - 0.12 12.1 0.7 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KIK57337.1 - 0.12 12.6 0.0 5.5 7.3 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 KIK57337.1 - 0.12 11.3 3.0 3.8 6.4 0.1 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KIK57337.1 - 0.14 11.9 0.4 17 5.2 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Coatomer_WDAD PF04053.14 KIK57342.1 - 5.6e-140 467.3 0.0 1.2e-139 466.2 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KIK57342.1 - 5.3e-40 134.7 6.2 3.8e-07 30.7 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57342.1 - 2.7e-09 37.2 0.2 0.011 16.0 0.0 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK57342.1 - 8.6e-05 21.4 1.1 0.35 9.5 0.0 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Prenyltrans PF00432.21 KIK57343.1 - 5.6e-05 22.8 0.7 0.59 9.9 0.0 3.8 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat CPDase PF07823.11 KIK57343.1 - 0.067 12.9 0.3 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Coatomer_WDAD PF04053.14 KIK57344.1 - 1.3e-45 156.3 0.0 1.5e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region Prenyltrans PF00432.21 KIK57345.1 - 0.0029 17.3 0.1 2.5 7.9 0.0 3.1 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Coatomer_WDAD PF04053.14 KIK57346.1 - 2.5e-53 181.7 2.3 8.1e-31 107.5 0.3 2.8 1 1 2 3 3 3 3 Coatomer WD associated region DUF3093 PF11292.8 KIK57350.1 - 0.32 11.2 2.8 0.87 9.8 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Dioxygenase_C PF00775.21 KIK57352.1 - 6.9e-08 32.1 0.2 4.9e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 Dioxygenase zf-H2C2_2 PF13465.6 KIK57353.1 - 7.3e-08 32.5 4.4 1.6e-05 25.1 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIK57353.1 - 8.4e-05 22.2 9.7 0.0012 18.5 2.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIK57353.1 - 0.00024 21.7 6.4 0.44 11.5 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KIK57353.1 - 0.0028 17.9 3.4 1.1 9.7 0.9 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KIK57353.1 - 0.0031 17.9 5.8 0.95 10.1 0.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KIK57353.1 - 0.038 14.4 0.3 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KIK57353.1 - 0.72 10.6 6.0 11 6.8 2.3 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger Pkinase PF00069.25 KIK57356.1 - 6.8e-07 28.9 0.0 7.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK57356.1 - 0.00043 20.3 0.1 0.00075 19.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK57356.1 - 0.0023 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK57356.1 - 0.031 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIK57356.1 - 0.032 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FBPase_3 PF01950.16 KIK57357.1 - 0.098 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase Lentivirus_VIF PF05851.11 KIK57358.1 - 0.03 13.2 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) NAD_binding_6 PF08030.12 KIK57358.1 - 0.031 14.4 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PI-PLC-X PF00388.19 KIK57359.1 - 0.00049 19.7 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Lactonase PF10282.9 KIK57360.1 - 4.3e-30 105.1 0.0 8.4e-29 100.9 0.0 2.0 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Proteasome PF00227.26 KIK57361.1 - 3e-41 141.0 0.0 3.7e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_binding_7 PF13241.6 KIK57361.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GLE1 PF07817.13 KIK57362.1 - 1.6e-51 175.0 0.0 2.5e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein Macoilin PF09726.9 KIK57362.1 - 0.49 8.9 36.2 0.69 8.4 36.2 1.1 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 KIK57362.1 - 1.2 7.2 36.1 1.7 6.6 36.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 KIK57367.1 - 4.4e-19 68.5 27.4 2.3e-08 34.6 1.6 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57367.1 - 9.3e-11 41.9 0.8 3.7e-06 27.1 0.0 4.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK57367.1 - 0.00027 20.8 6.1 0.39 10.7 0.0 5.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK57367.1 - 0.012 14.6 0.0 11 4.8 0.0 3.6 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK57367.1 - 0.024 14.5 0.0 0.095 12.6 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KIK57367.1 - 0.05 11.6 0.0 0.077 11.0 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Frtz PF11768.8 KIK57367.1 - 0.095 11.0 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK57367.1 - 0.14 11.8 3.5 21 4.9 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature AP_endonuc_2 PF01261.24 KIK57369.1 - 3.8e-24 85.3 0.0 6.1e-24 84.6 0.0 1.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Met_asp_mut_E PF06368.11 KIK57369.1 - 0.11 11.0 0.1 0.17 10.3 0.1 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Fungal_trans PF04082.18 KIK57370.1 - 3e-08 33.0 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.9 KIK57372.1 - 1.1e-25 90.7 0.0 1.3e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Mo25 PF08569.11 KIK57373.1 - 2.8e-133 444.3 3.7 3.2e-133 444.1 3.7 1.0 1 0 0 1 1 1 1 Mo25-like Spore_GerQ PF09671.10 KIK57373.1 - 0.031 14.3 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) Pkinase PF00069.25 KIK57374.1 - 1.1e-24 87.3 0.0 5.2e-24 85.0 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57374.1 - 3.8e-11 42.8 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK57374.1 - 0.00055 19.3 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK57374.1 - 0.0032 16.3 0.7 0.0045 15.8 0.7 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK57374.1 - 0.056 12.8 0.1 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KIK57374.1 - 0.059 12.3 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KIK57374.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 KIK57375.1 - 3.8e-12 46.5 3.5 0.0042 17.9 0.0 5.6 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57375.1 - 2.7e-09 37.2 0.0 0.006 16.9 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KIK57375.1 - 0.00035 18.7 0.1 0.00054 18.1 0.1 1.2 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.12 KIK57375.1 - 0.024 14.6 1.9 16 5.6 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK57376.1 - 0.0036 18.1 1.8 0.005 17.6 0.3 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57376.1 - 0.11 12.8 0.0 0.59 10.5 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_90 PF05686.12 KIK57378.1 - 4e-19 68.8 0.3 1.2e-18 67.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 90 Inositol_P PF00459.25 KIK57379.1 - 1.7e-55 188.4 0.0 1.9e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DS PF01916.17 KIK57380.1 - 0.031 13.5 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Deoxyhypusine synthase EF-hand_1 PF00036.32 KIK57380.1 - 0.065 12.8 0.0 0.36 10.5 0.0 2.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KIK57380.1 - 0.11 12.5 0.0 0.83 9.7 0.0 2.5 1 0 0 1 1 1 0 EF-hand domain NPV_P10 PF05531.12 KIK57380.1 - 0.11 13.0 1.8 11 6.6 0.1 3.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RLAN PF14401.6 KIK57380.1 - 0.13 11.9 0.6 6 6.5 0.1 2.4 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain EF-hand_5 PF13202.6 KIK57380.1 - 0.89 9.2 4.7 0.21 11.1 0.1 2.4 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.22 KIK57383.1 - 2.2e-05 24.2 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JTB PF05439.12 KIK57384.1 - 0.18 11.8 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Chromo PF00385.24 KIK57385.1 - 3.6e-12 46.0 0.7 9.7e-12 44.6 0.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2635 PF10948.8 KIK57385.1 - 0.06 13.1 1.5 0.32 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2635) DAZAP2 PF11029.8 KIK57385.1 - 0.09 13.7 0.2 0.09 13.7 0.2 1.6 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) PPL4 PF18188.1 KIK57387.1 - 0.16 11.9 0.1 0.28 11.1 0.0 1.4 2 0 0 2 2 2 0 Prim-pol 4 PHO4 PF01384.20 KIK57388.1 - 3.4 6.6 9.2 9 5.2 9.2 1.8 1 1 0 1 1 1 0 Phosphate transporter family Acetyltransf_1 PF00583.25 KIK57389.1 - 2.6e-11 43.8 0.0 3.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK57389.1 - 1.7e-09 37.7 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK57389.1 - 5.3e-09 36.4 0.0 7.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK57389.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_1 PF00232.18 KIK57390.1 - 9.3e-107 357.2 1.1 1.3e-106 356.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 CMAS PF02353.20 KIK57391.1 - 0.031 13.6 0.0 3.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIK57391.1 - 0.043 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain OPT PF03169.15 KIK57392.1 - 2.3e-132 442.7 44.3 2.7e-132 442.5 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Bac_export_2 PF01312.19 KIK57392.1 - 0.27 10.4 3.7 0.11 11.7 0.4 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Transferase PF02458.15 KIK57394.1 - 0.061 12.0 0.0 0.091 11.4 0.0 1.4 1 1 0 1 1 1 0 Transferase family Phage_holin_5_2 PF16079.5 KIK57395.1 - 0.51 10.7 10.6 6.7 7.1 0.4 4.1 2 2 3 5 5 5 0 Phage holin family Hol44, in holin superfamily V FAD_binding_4 PF01565.23 KIK57397.1 - 2.9e-20 72.4 0.8 5.2e-20 71.6 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK57397.1 - 7.4e-09 35.6 0.1 4.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like DUF5518 PF17647.1 KIK57397.1 - 0.64 10.2 6.3 1.4 9.1 6.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Abhydrolase_6 PF12697.7 KIK57398.1 - 8.8e-11 42.8 1.3 2.4e-10 41.4 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family CMD PF02627.20 KIK57398.1 - 1.8e-09 37.5 0.1 8.5e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Abhydrolase_1 PF00561.20 KIK57398.1 - 1.9e-08 34.3 0.1 2.4e-07 30.7 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK57398.1 - 3.9e-05 23.0 0.0 0.00012 21.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIK57398.1 - 0.0045 16.7 0.1 0.008 15.9 0.1 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KIK57398.1 - 0.038 12.7 0.1 0.059 12.0 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ribosomal_L24e PF01246.20 KIK57399.1 - 1.2e-30 105.6 0.3 1.2e-30 105.6 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Ets PF00178.22 KIK57399.1 - 0.059 13.8 0.5 0.11 12.9 0.5 1.4 1 0 0 1 1 1 0 Ets-domain ATP-synt_E PF05680.12 KIK57399.1 - 4.8 7.6 10.2 13 6.2 6.5 2.1 1 1 1 2 2 2 0 ATP synthase E chain p450 PF00067.22 KIK57400.1 - 1.8e-63 214.9 0.0 3.1e-62 210.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Synaptobrevin PF00957.21 KIK57401.1 - 7.6e-12 44.9 0.6 2.3e-06 27.3 0.1 2.1 2 0 0 2 2 2 2 Synaptobrevin WD40 PF00400.32 KIK57402.1 - 2.7e-09 37.5 8.7 0.0085 16.9 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57402.1 - 1.6e-06 28.3 0.2 0.16 12.3 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ATP_sub_h PF10775.9 KIK57402.1 - 2.1 8.4 5.4 0.34 10.9 0.3 2.3 2 0 0 2 2 2 0 ATP synthase complex subunit h Sigma70_r3 PF04539.16 KIK57403.1 - 0.0015 18.6 0.0 0.0046 17.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 3 AroM PF07302.11 KIK57404.1 - 0.086 12.2 0.0 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 AroM protein MarR_2 PF12802.7 KIK57409.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 MarR family Thia_YuaJ PF09515.10 KIK57410.1 - 0.045 13.8 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) Pkinase PF00069.25 KIK57411.1 - 8.8e-22 77.7 0.0 7.4e-21 74.7 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57411.1 - 2.1e-09 37.0 0.0 3.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_ligase_A_M PF01068.21 KIK57415.1 - 2e-51 174.5 0.0 3.8e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK57415.1 - 5.8e-36 124.4 0.0 1.6e-35 123.0 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KIK57415.1 - 5.8e-14 52.7 0.1 1.1e-13 51.8 0.1 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 KIK57415.1 - 3.4e-11 43.6 0.0 1.1e-10 41.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KIK57415.1 - 3.5e-11 43.3 0.0 1.1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain mRNA_cap_enzyme PF01331.19 KIK57415.1 - 0.00074 19.4 0.4 0.0036 17.2 0.4 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain BRCT PF00533.26 KIK57415.1 - 0.083 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain TPP_enzyme_N PF02776.18 KIK57416.1 - 2.8e-34 118.2 0.0 4.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIK57416.1 - 2e-15 56.9 0.0 5.3e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK57416.1 - 1e-14 54.5 0.1 2.1e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Acyl-CoA_dh_1 PF00441.24 KIK57418.1 - 2.4e-34 118.7 0.7 5.1e-34 117.7 0.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK57418.1 - 1.8e-25 88.9 0.0 4.3e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIK57418.1 - 9.1e-23 81.1 0.0 2.2e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK57418.1 - 6.1e-15 55.7 0.2 1e-14 55.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KIK57418.1 - 0.0037 17.0 0.0 0.027 14.2 0.0 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal WH1 PF00568.23 KIK57419.1 - 3.2e-21 75.3 0.0 5.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KIK57419.1 - 3.1e-07 30.6 0.0 7.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 KIK57419.1 - 0.002 17.9 0.3 0.0044 16.8 0.3 1.6 1 0 0 1 1 1 1 WH2 motif WD40 PF00400.32 KIK57420.1 - 6.7e-07 29.9 0.7 0.0073 17.1 0.0 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57420.1 - 0.00034 20.9 0.1 4.1 7.8 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK57420.1 - 0.088 12.8 0.6 29 4.7 0.1 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Mei4 PF13971.6 KIK57420.1 - 0.14 11.6 0.1 0.41 10.1 0.1 1.6 1 1 1 2 2 2 0 Meiosis-specific protein Mei4 DUF2070 PF09843.9 KIK57420.1 - 0.33 9.2 6.1 0.5 8.6 6.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CREPT PF16566.5 KIK57421.1 - 0.92 9.7 12.0 0.62 10.2 4.5 3.2 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour VIT PF08487.10 KIK57423.1 - 7.6e-11 42.2 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK57423.1 - 2.3e-09 37.4 0.0 3.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK57423.1 - 0.0029 17.9 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Cbl_N PF02262.16 KIK57423.1 - 0.037 14.0 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Hydantoinase_B PF02538.14 KIK57424.1 - 1.3e-209 696.9 0.2 1.5e-209 696.7 0.2 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Acyl-CoA_dh_1 PF00441.24 KIK57425.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK57425.1 - 0.0017 18.5 0.0 0.0046 17.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain FAD_binding_3 PF01494.19 KIK57426.1 - 1.4e-07 31.1 0.0 3.4e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK57426.1 - 8e-06 25.3 0.0 0.03 13.6 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK57426.1 - 8.6e-06 25.3 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK57426.1 - 1.3e-05 25.3 0.2 3.2e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK57426.1 - 0.0001 22.0 0.7 0.18 11.3 0.1 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK57426.1 - 0.0016 18.9 0.0 0.15 12.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Antimicrobial23 PF16048.5 KIK57426.1 - 0.029 14.0 0.6 0.052 13.2 0.6 1.3 1 0 0 1 1 1 0 Frog antimicrobial peptide FAD_binding_2 PF00890.24 KIK57426.1 - 0.077 12.1 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF3015 PF11220.8 KIK57427.1 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Hemopexin PF00045.19 KIK57428.1 - 8.9e-13 48.0 0.0 6.6e-06 26.0 0.0 4.2 4 1 0 4 4 4 3 Hemopexin Pkinase PF00069.25 KIK57429.1 - 2.9e-75 253.1 0.0 4e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57429.1 - 4.7e-42 144.1 0.0 6.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK57429.1 - 1.5e-12 47.5 0.0 2.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK57429.1 - 0.0036 16.7 0.1 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK57429.1 - 0.072 12.0 0.2 0.29 10.0 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK57429.1 - 0.61 8.8 0.0 0.61 8.8 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase Glyco_hydro_12 PF01670.16 KIK57430.1 - 3.3e-32 112.2 12.3 3.9e-32 112.0 12.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 FSH1 PF03959.13 KIK57431.1 - 1.7e-37 129.2 0.0 2.1e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIK57431.1 - 0.0047 16.6 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold T6SS_TssF PF05947.12 KIK57431.1 - 0.024 13.2 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssF Abhydrolase_2 PF02230.16 KIK57431.1 - 0.044 13.6 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2235 PF09994.9 KIK57431.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_12 PF01670.16 KIK57432.1 - 4.1e-30 105.4 10.3 4.8e-30 105.2 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF4124 PF13511.6 KIK57432.1 - 0.069 13.5 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) PPV_E2_C PF00511.17 KIK57432.1 - 4.4 7.6 7.3 7.1 6.9 2.1 2.4 2 0 0 2 2 2 0 E2 (early) protein, C terminal CFEM PF05730.11 KIK57433.1 - 1e-11 44.7 12.9 1.9e-11 43.9 12.9 1.4 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.11 KIK57433.1 - 6.3 4.8 13.9 8.3 4.4 13.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PTR2 PF00854.21 KIK57436.1 - 2.9e-85 286.5 8.5 3.8e-85 286.1 8.5 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KIK57436.1 - 5e-12 45.4 21.1 5e-12 45.4 21.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily L51_S25_CI-B8 PF05047.16 KIK57437.1 - 2.2e-14 53.1 0.1 3.2e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 KIK57437.1 - 0.049 12.9 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain RGS PF00615.19 KIK57438.1 - 9.1e-09 35.6 1.6 0.00099 19.4 0.3 2.9 2 1 0 2 2 2 2 Regulator of G protein signaling domain Fox-1_C PF12414.8 KIK57438.1 - 0.15 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Pkinase PF00069.25 KIK57440.1 - 1.2e-49 169.1 0.0 1.7e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57440.1 - 4.5e-19 68.8 0.0 1.2e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK57440.1 - 2.9e-07 30.1 0.0 7.8e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KIK57440.1 - 0.00088 19.3 0.4 0.012 15.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK57440.1 - 0.004 16.0 0.0 0.006 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK57440.1 - 0.17 11.2 1.0 0.24 10.7 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1772 PF08592.11 KIK57441.1 - 0.068 13.5 5.1 0.7 10.2 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) ESSS PF10183.9 KIK57441.1 - 0.65 10.2 2.9 4 7.7 0.2 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EF-hand_1 PF00036.32 KIK57442.1 - 3.4e-42 138.9 13.3 8.5e-10 37.5 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK57442.1 - 1.5e-35 121.5 3.2 8.8e-18 64.5 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KIK57442.1 - 1.3e-32 111.4 11.2 1.4e-15 56.8 0.6 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KIK57442.1 - 2.3e-30 101.9 7.2 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIK57442.1 - 4.8e-27 92.2 10.3 2.1e-06 27.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KIK57442.1 - 1e-15 57.8 0.1 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIK57442.1 - 3.7e-10 39.7 0.9 3e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIK57442.1 - 2.5e-08 34.2 0.0 0.0021 18.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KIK57442.1 - 2.4e-06 27.5 0.0 0.042 13.9 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KIK57442.1 - 6.8e-05 23.7 0.0 0.037 14.9 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KIK57442.1 - 0.00029 20.9 4.1 0.091 13.0 0.3 3.1 1 1 1 2 2 2 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 KIK57442.1 - 0.00034 20.6 0.7 0.0019 18.3 0.1 2.2 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 KIK57442.1 - 0.00059 19.5 0.9 0.00068 19.3 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KIK57442.1 - 0.00066 19.6 0.6 0.4 10.6 0.0 3.3 1 1 2 3 3 3 1 Caleosin related protein Poly_export PF02563.16 KIK57442.1 - 0.0031 17.7 0.1 0.29 11.4 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KIK57442.1 - 0.004 17.6 0.0 1 9.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 KIK57442.1 - 0.0053 16.7 0.1 0.48 10.4 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 KIK57442.1 - 0.0059 15.2 0.0 0.0059 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 KIK57442.1 - 0.01 16.2 0.2 7.1 7.0 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 MotA_activ PF09114.10 KIK57442.1 - 0.011 15.8 0.3 0.18 11.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 KIK57442.1 - 0.013 15.3 0.4 0.78 9.6 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Spore_III_AB PF09548.10 KIK57442.1 - 0.023 14.8 0.2 0.036 14.2 0.2 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) dCache_2 PF08269.11 KIK57442.1 - 0.036 13.2 0.1 2.5 7.2 0.0 2.2 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 KIK57442.1 - 0.053 13.9 0.1 9.3 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 KIK57442.1 - 0.098 12.9 0.0 25 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Fe_hyd_lg_C PF02906.14 KIK57442.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.6 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain F_bP_aldolase PF01116.20 KIK57444.1 - 2.5e-56 191.2 0.0 2.8e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II EF-hand_1 PF00036.32 KIK57445.1 - 9.5e-39 128.1 13.7 2.3e-09 36.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK57445.1 - 8.3e-34 115.9 3.4 1.6e-16 60.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK57445.1 - 1.7e-29 99.2 9.7 3.5e-09 35.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIK57445.1 - 4.9e-29 99.9 12.1 1.3e-13 50.5 0.7 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KIK57445.1 - 2.2e-25 87.0 12.3 1.7e-07 30.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KIK57445.1 - 6.7e-15 55.2 0.1 5.2e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KIK57445.1 - 3.4e-08 33.8 0.0 0.001 19.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KIK57445.1 - 1.8e-07 31.0 1.2 0.01 15.8 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 KIK57445.1 - 2.9e-06 27.2 0.1 0.022 14.8 0.0 3.0 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.16 KIK57445.1 - 4.9e-06 26.9 0.8 0.012 16.0 0.1 3.1 2 1 1 3 3 3 1 RNA polymerase Rpb4 Caleosin PF05042.13 KIK57445.1 - 0.00019 21.4 0.6 0.48 10.3 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EF-hand_11 PF08976.11 KIK57445.1 - 0.0002 22.2 0.0 0.29 12.0 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 KIK57445.1 - 0.00047 20.2 0.6 0.0058 16.7 0.1 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 KIK57445.1 - 0.0005 20.0 1.0 0.094 12.7 0.1 2.5 1 1 2 3 3 3 1 Tellurite resistance protein TerB Dockerin_1 PF00404.18 KIK57445.1 - 0.0012 19.0 3.9 0.18 12.0 0.5 2.8 2 2 1 3 3 3 2 Dockerin type I domain DUF4497 PF14924.6 KIK57445.1 - 0.0017 18.8 0.0 0.5 10.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) DUF3349 PF11829.8 KIK57445.1 - 0.0031 18.3 0.1 4.8 8.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) EF-hand_14 PF17959.1 KIK57445.1 - 0.0045 17.3 0.2 0.68 10.3 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain SurA_N_2 PF13623.6 KIK57445.1 - 0.0057 16.5 1.1 0.35 10.7 0.3 2.4 1 1 1 2 2 2 1 SurA N-terminal domain dCache_2 PF08269.11 KIK57445.1 - 0.014 14.6 0.1 0.71 9.0 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5580 PF17743.1 KIK57445.1 - 0.015 13.9 0.0 0.016 13.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) FGAR-AT_linker PF18072.1 KIK57445.1 - 0.017 15.6 0.1 0.97 10.0 0.0 2.6 2 2 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF1296 PF06972.11 KIK57445.1 - 0.026 14.6 0.5 3.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Toprim_4 PF13662.6 KIK57445.1 - 0.04 14.4 0.2 3.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Toprim domain Spore_III_AB PF09548.10 KIK57445.1 - 0.042 14.0 0.5 0.076 13.1 0.5 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF2267 PF10025.9 KIK57445.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Cytochrome_CBB3 PF13442.6 KIK57445.1 - 0.12 12.7 0.1 2.6 8.4 0.0 2.4 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III RloB PF13707.6 KIK57445.1 - 0.23 11.6 1.4 0.95 9.6 0.3 2.0 1 1 0 2 2 2 0 RloB-like protein DNA_ligase_OB_2 PF14743.6 KIK57446.1 - 3.5e-28 97.4 0.3 7.4e-28 96.4 0.3 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KIK57446.1 - 1.5e-11 44.3 0.0 3.6e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain SWIM PF04434.17 KIK57446.1 - 0.00083 19.0 3.8 0.23 11.2 0.5 2.8 2 2 0 2 2 2 2 SWIM zinc finger F-box-like PF12937.7 KIK57447.1 - 0.00096 19.0 0.2 0.0033 17.3 0.2 1.9 1 1 0 1 1 1 1 F-box-like VitK2_biosynth PF02621.14 KIK57447.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis Sin3_corepress PF08295.12 KIK57449.1 - 0.082 13.0 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Sin3 family co-repressor HMG_box_2 PF09011.10 KIK57450.1 - 3.3e-14 53.2 13.4 6.9e-07 29.8 3.8 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KIK57450.1 - 4.5e-12 46.2 18.4 5.2e-07 30.0 0.9 2.7 3 0 0 3 3 3 2 HMG (high mobility group) box Protamine_like PF06382.11 KIK57450.1 - 0.0025 18.0 21.1 0.015 15.5 0.6 2.8 2 1 0 2 2 2 2 Protamine and protamine like DUF948 PF06103.11 KIK57450.1 - 0.023 14.9 0.9 0.086 13.1 0.9 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SMYLE_N PF18615.1 KIK57450.1 - 0.087 12.4 6.5 0.12 11.9 6.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PG_binding_1 PF01471.18 KIK57450.1 - 0.24 11.6 1.8 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain YABBY PF04690.13 KIK57450.1 - 2 9.0 14.0 9.9 6.7 10.4 2.1 1 1 1 2 2 2 0 YABBY protein zf-C2H2 PF00096.26 KIK57451.1 - 0.0039 17.6 9.2 0.016 15.7 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KIK57451.1 - 0.062 13.1 1.5 0.19 11.5 1.5 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type AMP-binding PF00501.28 KIK57454.1 - 5.6e-73 245.9 0.0 1.1e-72 245.0 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK57454.1 - 4.8e-11 43.5 0.0 1.4e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FA_desaturase PF00487.24 KIK57455.1 - 1.3e-17 64.5 24.8 2.4e-17 63.6 24.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK57455.1 - 1.8e-12 47.2 0.0 3.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SGL PF08450.12 KIK57456.1 - 5.4e-27 95.0 0.0 8.3e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK57456.1 - 2.7e-06 27.4 0.0 2.4e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KIK57456.1 - 7.3e-05 22.9 0.1 0.00047 20.3 0.0 2.5 1 1 1 2 2 2 1 Arylesterase NHL PF01436.21 KIK57456.1 - 0.00018 21.4 0.3 0.0049 16.8 0.0 2.8 2 0 0 2 2 2 1 NHL repeat PD40 PF07676.12 KIK57456.1 - 0.11 12.5 0.1 1 9.4 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SBBP PF06739.11 KIK57456.1 - 0.13 12.3 2.6 5.6 7.0 0.2 2.7 2 0 0 2 2 2 0 Beta-propeller repeat RNase_PH PF01138.21 KIK57457.1 - 1.4e-24 87.1 0.0 2.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK57457.1 - 0.0052 16.8 0.0 0.032 14.3 0.0 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 Aldo_ket_red PF00248.21 KIK57459.1 - 4.5e-64 216.4 0.0 5.2e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK57460.1 - 8.6e-66 222.1 0.0 9.8e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MDD_C PF18376.1 KIK57461.1 - 1.2e-69 233.8 0.0 1.6e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KIK57461.1 - 3.8e-07 30.3 4.8 7.4e-07 29.3 4.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain UreF PF01730.16 KIK57461.1 - 0.12 12.9 0.0 1.6 9.3 0.0 2.1 2 0 0 2 2 2 0 UreF Epimerase PF01370.21 KIK57462.1 - 3.8e-17 62.6 0.0 5.2e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK57462.1 - 7e-15 54.8 0.0 1.6e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK57462.1 - 1.8e-14 53.6 0.0 4.1e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK57462.1 - 3.1e-09 36.7 0.1 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK57462.1 - 8.2e-09 35.6 0.0 1.9e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK57462.1 - 1.3e-07 31.5 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK57462.1 - 0.00018 21.0 0.1 0.00039 19.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK57462.1 - 0.0034 17.3 0.2 0.0068 16.3 0.2 1.5 1 1 0 1 1 1 1 KR domain Aminotran_1_2 PF00155.21 KIK57463.1 - 1.3e-34 120.0 0.0 8.6e-34 117.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIK57463.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIK57463.1 - 0.0053 15.3 0.0 0.0086 14.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cyclin_N PF00134.23 KIK57464.1 - 3.3e-12 46.2 0.3 1.8e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIK57464.1 - 0.013 15.8 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain Cyclin_C PF02984.19 KIK57464.1 - 0.19 11.8 2.6 1.7 8.7 0.8 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain IucA_IucC PF04183.12 KIK57465.1 - 1.5e-29 103.2 0.1 2.3e-29 102.6 0.1 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 KIK57465.1 - 3.8e-11 43.7 0.0 7.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter DUF1801 PF08818.11 KIK57465.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DU1801) Glyco_hyd_65N_2 PF14498.6 KIK57466.1 - 1.7e-46 159.0 0.0 2.5e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Aconitase PF00330.20 KIK57468.1 - 7.6e-154 513.1 0.1 9.4e-154 512.8 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK57468.1 - 1.1e-44 152.0 0.0 1.8e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SpoVAB PF13782.6 KIK57469.1 - 0.047 14.0 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AB AbiJ_NTD5 PF18865.1 KIK57469.1 - 0.11 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF3106 PF11304.8 KIK57471.1 - 0.057 13.9 3.4 0.087 13.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DM13 PF10517.9 KIK57471.1 - 0.085 13.4 0.1 0.23 12.0 0.1 1.7 1 1 0 1 1 1 0 Electron transfer DM13 MDM10 PF12519.8 KIK57471.1 - 1.7 7.4 6.5 2.1 7.1 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Replic_Relax PF13814.6 KIK57472.1 - 0.017 15.2 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation MDM1 PF15501.6 KIK57475.1 - 0.035 13.3 8.4 0.038 13.2 8.4 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Flu_B_M2 PF04772.12 KIK57475.1 - 0.1 12.8 0.8 0.36 11.1 0.1 2.1 1 1 0 2 2 2 0 Influenza B matrix protein 2 (BM2) Vfa1 PF08432.10 KIK57475.1 - 0.16 12.3 9.3 0.21 11.9 9.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HA2 PF04408.23 KIK57475.1 - 0.23 11.8 2.7 0.36 11.1 2.7 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) Med19 PF10278.9 KIK57475.1 - 3 7.7 8.7 4.4 7.2 8.7 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Amino_oxidase PF01593.24 KIK57476.1 - 1.9e-10 40.7 0.0 5e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK57476.1 - 8.4e-10 38.7 0.0 1.8e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK57476.1 - 3.5e-05 22.7 0.0 6.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIK57476.1 - 5.2e-05 22.6 0.0 0.00022 20.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK57476.1 - 8.9e-05 21.9 0.0 0.0018 17.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK57476.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK57476.1 - 0.00031 20.4 0.1 0.00062 19.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK57476.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIK57476.1 - 0.0032 16.6 0.1 0.0049 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK57476.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK57476.1 - 0.03 14.9 0.1 0.43 11.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK57476.1 - 0.038 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KIK57476.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KIK57476.1 - 0.22 10.6 0.1 0.34 9.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_1 PF00667.20 KIK57477.1 - 3.2e-37 128.3 0.0 5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIK57477.1 - 3.1e-27 95.6 0.0 5.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KIK57477.1 - 5.3e-11 43.1 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIK57477.1 - 0.015 15.6 0.1 0.081 13.2 0.0 2.3 2 1 1 3 3 3 0 Flavodoxin domain GAT PF03127.14 KIK57477.1 - 0.15 12.4 0.0 0.61 10.4 0.0 2.0 1 0 0 1 1 1 0 GAT domain NAD_binding_8 PF13450.6 KIK57478.1 - 6.6e-11 42.3 0.0 1.4e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK57478.1 - 4e-09 36.3 0.0 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KIK57478.1 - 4.3e-06 26.6 0.0 4.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK57478.1 - 5.4e-05 22.6 0.0 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK57478.1 - 6.9e-05 21.7 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KIK57478.1 - 0.00018 20.9 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK57478.1 - 0.00066 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK57478.1 - 0.0021 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK57478.1 - 0.0024 17.0 0.1 0.0038 16.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK57478.1 - 0.0034 16.7 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 KIK57478.1 - 0.0051 17.0 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 KIK57478.1 - 0.0084 16.7 0.1 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK57478.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK57478.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein BetaGal_dom4_5 PF13364.6 KIK57479.1 - 0.031 14.8 0.0 0.043 14.4 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain SNase PF00565.17 KIK57480.1 - 1.4e-19 70.6 0.0 2.1e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PA14 PF07691.12 KIK57481.1 - 0.0007 19.4 0.0 0.002 17.9 0.0 1.7 2 0 0 2 2 2 1 PA14 domain Bac_rhamnosid_N PF08531.10 KIK57481.1 - 0.00082 19.2 0.1 0.0059 16.4 0.0 2.1 1 1 1 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Arylsulfotran_2 PF14269.6 KIK57482.1 - 3.9e-53 180.8 5.6 7.5e-53 179.8 5.6 1.5 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK57482.1 - 1.5e-14 53.7 0.2 8.5e-14 51.2 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) S-l_SbsC_C PF18316.1 KIK57482.1 - 2.4 8.7 6.9 0.42 11.1 1.7 2.5 3 0 0 3 3 3 0 S-layer protein SbsC C-terminal domain AAA_12 PF13087.6 KIK57484.1 - 6.3e-42 143.5 0.0 9.7e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK57484.1 - 1.6e-22 80.6 0.4 6.9e-14 52.3 0.0 3.2 3 0 0 3 3 3 3 AAA domain AAA_19 PF13245.6 KIK57484.1 - 2.7e-10 40.7 0.0 1.1e-09 38.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK57484.1 - 8.9e-09 35.3 0.0 7.4e-07 29.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KIK57484.1 - 0.00039 20.1 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KIK57484.1 - 0.00078 19.3 0.0 0.0078 16.1 0.0 2.2 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 KIK57484.1 - 0.0077 16.6 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KIK57484.1 - 0.0081 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KIK57484.1 - 0.0086 15.8 0.0 7.4 6.2 0.0 3.4 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIK57484.1 - 0.032 13.5 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 KIK57484.1 - 0.033 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KIK57484.1 - 0.065 12.4 0.0 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Ldh_2 PF02615.14 KIK57484.1 - 0.11 11.7 0.1 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Malate/L-lactate dehydrogenase AAA_22 PF13401.6 KIK57484.1 - 0.14 12.5 0.0 0.6 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 KIK57484.1 - 0.14 11.5 0.1 2.1 7.6 0.0 2.1 1 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KIK57484.1 - 0.19 12.1 0.0 0.63 10.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Integrase_H2C2 PF17921.1 KIK57485.1 - 4.1e-08 33.2 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H3C2 PF16721.5 KIK57485.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding Pkinase_Tyr PF07714.17 KIK57486.1 - 6.2e-38 130.6 0.0 8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK57486.1 - 2.2e-32 112.5 0.0 3.2e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 KIK57486.1 - 9.9e-09 35.2 7.2 2.1e-08 34.1 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIO1 PF01163.22 KIK57486.1 - 0.028 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MBF2 PF15868.5 KIK57486.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcription activator MBF2 Pkinase_fungal PF17667.1 KIK57486.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Catalase PF00199.19 KIK57487.1 - 2.7e-162 540.2 0.3 3.9e-162 539.7 0.0 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 KIK57487.1 - 4.4e-16 58.8 0.2 1.2e-15 57.5 0.2 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive BOFC_N PF08977.10 KIK57489.1 - 0.11 12.5 0.1 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal Mito_carr PF00153.27 KIK57490.1 - 2.5e-62 206.8 5.9 1.2e-21 76.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4574 PF15141.6 KIK57490.1 - 0.037 13.9 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 ssDNA_TraI_N PF18272.1 KIK57490.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Serine_protease PF18405.1 KIK57490.1 - 0.062 12.5 2.4 0.36 9.9 0.2 2.7 1 1 1 3 3 3 0 Gammaproteobacterial serine protease Tmemb_14 PF03647.13 KIK57490.1 - 0.073 13.8 4.5 0.5 11.1 0.0 3.2 2 2 1 3 3 3 0 Transmembrane proteins 14C Retrotran_gag_2 PF14223.6 KIK57491.1 - 1.5e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type dUTPase_2 PF08761.11 KIK57491.1 - 0.082 13.1 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 dUTPase zf-MYND PF01753.18 KIK57494.1 - 2.1e-05 24.5 19.3 0.00015 21.8 19.3 2.5 1 1 0 1 1 1 1 MYND finger Med12 PF09497.10 KIK57494.1 - 0.13 12.6 0.2 3.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 XPA_C PF05181.12 KIK57496.1 - 0.098 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 XPA protein C-terminus TrkH PF02386.16 KIK57497.1 - 1.5e-88 297.4 12.2 4e-87 292.8 5.5 2.1 2 0 0 2 2 2 2 Cation transport protein Catalase PF00199.19 KIK57498.1 - 3.6e-163 543.1 0.0 4.3e-163 542.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK57498.1 - 7.1e-16 58.2 0.1 1.9e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Retrotrans_gag PF03732.17 KIK57499.1 - 8.4e-06 26.0 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK57499.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF3972 PF13118.6 KIK57501.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Macro PF01661.21 KIK57502.1 - 4.5e-16 59.0 0.0 8.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Macro domain DUF5549 PF17703.1 KIK57502.1 - 1.2 8.8 7.4 0.61 9.7 5.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5549) DUF667 PF05018.13 KIK57504.1 - 0.0044 16.8 0.0 0.0055 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DUF2897 PF11446.8 KIK57504.1 - 0.57 10.1 3.4 1.2 9.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF202 PF02656.15 KIK57504.1 - 6.6 7.3 8.4 6.8 7.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GPP34 PF05719.11 KIK57505.1 - 1.6e-58 198.1 0.0 1.2e-57 195.2 0.0 1.9 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) LRR_6 PF13516.6 KIK57506.1 - 0.23 11.6 0.5 16 5.9 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat F-box-like PF12937.7 KIK57507.1 - 3.4e-07 30.0 0.5 1e-06 28.5 0.5 1.8 1 1 0 1 1 1 1 F-box-like RPN2_C PF18004.1 KIK57507.1 - 0.098 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ras PF00071.22 KIK57510.1 - 1.3e-46 158.2 0.4 1.4e-46 158.0 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK57510.1 - 3.8e-17 62.6 0.0 5.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK57510.1 - 1.8e-08 34.0 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK57510.1 - 1.2e-05 25.4 0.0 2.3e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK57510.1 - 0.00026 20.9 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KIK57510.1 - 0.00037 20.5 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KIK57510.1 - 0.0019 17.8 0.1 0.021 14.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KIK57510.1 - 0.018 15.0 0.4 0.022 14.7 0.4 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIK57510.1 - 0.022 15.1 0.0 0.029 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KIK57510.1 - 0.027 14.5 0.2 0.04 14.0 0.2 1.7 1 1 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.17 KIK57510.1 - 0.035 13.9 0.1 0.95 9.2 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KIK57510.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIK57510.1 - 0.081 12.1 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit WD40 PF00400.32 KIK57511.1 - 4.8e-09 36.7 1.5 3.1e-05 24.7 0.2 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.7 KIK57511.1 - 5.6e-06 26.2 0.2 1.2e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KIK57511.1 - 4.7e-05 23.6 0.0 0.0025 18.1 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KIK57511.1 - 0.00014 21.7 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK57511.1 - 0.0018 18.1 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 F-box IDEAL PF08858.10 KIK57511.1 - 0.18 11.6 0.4 0.4 10.5 0.4 1.5 1 0 0 1 1 1 0 IDEAL domain UIM PF02809.20 KIK57511.1 - 0.3 11.1 5.7 0.11 12.5 0.7 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Lactonase PF10282.9 KIK57512.1 - 2e-09 37.2 0.0 7.8e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller FMO-like PF00743.19 KIK57513.1 - 6.1e-14 51.3 0.3 2.6e-13 49.2 0.0 2.2 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK57513.1 - 3.6e-12 46.1 0.0 4.1e-08 32.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK57513.1 - 1.2e-11 44.4 0.0 2.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK57513.1 - 5.7e-11 42.2 0.0 3.9e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK57513.1 - 4.3e-10 39.7 0.0 3.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK57513.1 - 9.6e-07 28.9 0.2 0.0054 16.7 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KIK57513.1 - 8.5e-06 25.6 0.4 0.00053 19.7 0.4 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK57513.1 - 1.2e-05 25.7 0.3 0.0021 18.6 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK57513.1 - 0.0056 16.8 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIK57513.1 - 0.029 13.1 0.0 0.077 11.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KIK57513.1 - 0.035 13.2 0.0 0.079 12.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIK57513.1 - 0.05 12.6 0.2 0.17 10.9 0.2 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIK57513.1 - 0.14 11.5 0.0 0.55 9.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KIK57513.1 - 0.18 10.9 0.0 24 3.9 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A BCAS2 PF05700.11 KIK57514.1 - 7.6e-05 22.5 0.2 0.00011 22.0 0.2 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mobilization_B PF17511.2 KIK57514.1 - 0.0022 18.4 0.7 0.0059 17.0 0.1 1.8 1 1 1 2 2 2 1 Mobilization protein B Ribosomal_S20p PF01649.18 KIK57514.1 - 0.025 15.2 0.4 0.041 14.5 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 Prefoldin PF02996.17 KIK57514.1 - 0.036 14.0 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit SlyX PF04102.12 KIK57514.1 - 0.048 14.3 1.9 0.082 13.5 1.7 1.5 1 1 0 1 1 1 0 SlyX DUF16 PF01519.16 KIK57514.1 - 0.13 12.7 1.3 0.17 12.4 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3138 PF11336.8 KIK57514.1 - 0.15 10.6 0.2 0.18 10.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1180 PF06679.12 KIK57518.1 - 0.5 10.8 1.6 0.72 10.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SANT_DAMP1_like PF16282.5 KIK57520.1 - 0.053 13.7 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 CxC4 PF18717.1 KIK57521.1 - 4.9e-45 152.6 0.4 8.8e-45 151.7 0.4 1.5 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases DUF2451 PF10474.9 KIK57521.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) KDZ PF18758.1 KIK57522.1 - 0.00047 19.8 1.0 0.00053 19.7 1.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Fungal_lectin PF07938.12 KIK57523.1 - 0.0015 18.0 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Fungal fucose-specific lectin NmrA PF05368.13 KIK57524.1 - 3.1e-15 56.4 0.0 4.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK57524.1 - 1.1e-05 25.5 0.1 0.00026 21.0 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Gp_dh_N PF00044.24 KIK57524.1 - 0.00048 20.4 0.2 0.0021 18.3 0.2 2.1 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIK57524.1 - 0.0014 18.9 0.0 0.003 17.8 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KIK57524.1 - 0.002 18.4 0.1 0.0051 17.1 0.1 1.8 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 KIK57524.1 - 0.002 18.2 0.7 0.0038 17.3 0.4 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KIK57524.1 - 0.0039 16.6 0.1 0.0098 15.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIK57524.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KIK57524.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KIK57524.1 - 0.069 13.3 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK57524.1 - 0.091 13.3 0.4 0.25 11.9 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 KIK57524.1 - 0.093 12.8 0.1 0.28 11.3 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KIK57524.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KIK57524.1 - 0.13 13.1 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DJ-1_PfpI PF01965.24 KIK57525.1 - 3.1e-20 72.6 0.0 6e-20 71.7 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 KIK57526.1 - 9.8e-21 74.3 0.0 1.8e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family PEMT PF04191.13 KIK57528.1 - 2.6e-31 108.2 2.6 6.5e-31 106.9 2.5 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Goodbye PF17109.5 KIK57529.1 - 7.6e-10 39.3 0.0 8.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain DUF1977 PF09320.11 KIK57531.1 - 1.7e-09 37.8 0.6 9.1e-09 35.5 0.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) Tau95_N PF17682.1 KIK57531.1 - 0.0068 16.6 0.0 0.0072 16.5 0.0 1.1 1 0 0 1 1 1 1 Tau95 Triple barrel domain HnRNP_M PF11532.8 KIK57531.1 - 0.19 12.0 3.2 0.45 10.8 3.2 1.6 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Pkinase PF00069.25 KIK57532.1 - 8.1e-09 35.2 0.0 1.7e-07 30.9 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57532.1 - 0.00037 19.9 0.0 0.0022 17.4 0.0 1.9 1 1 0 2 2 2 1 Protein tyrosine kinase DUF1011 PF06237.12 KIK57532.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) Glyco_hydro_65m PF03632.15 KIK57533.1 - 0.016 14.1 0.5 0.032 13.1 0.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain F-box-like PF12937.7 KIK57534.1 - 1.9e-06 27.6 0.7 1.9e-06 27.6 0.7 2.1 2 0 0 2 2 2 1 F-box-like PATR PF12951.7 KIK57536.1 - 6.8 6.9 10.6 1.2 9.4 4.9 2.7 2 1 0 2 2 2 0 Passenger-associated-transport-repeat F-box_4 PF15966.5 KIK57539.1 - 0.0041 17.0 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KIK57539.1 - 0.0096 15.8 1.0 0.0096 15.8 1.0 2.7 2 0 0 2 2 2 1 F-box-like PseudoU_synth_2 PF00849.22 KIK57540.1 - 5e-28 98.2 0.0 7.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF1180 PF06679.12 KIK57541.1 - 7.1 7.0 6.7 10 6.5 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2589 PF11655.8 KIK57542.1 - 2.9 8.2 10.3 19 5.6 1.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2589) LCCL PF03815.19 KIK57543.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 LCCL domain SNF2_N PF00176.23 KIK57545.1 - 3.9e-51 173.8 0.1 1.1e-50 172.3 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK57545.1 - 7.5e-17 61.7 0.0 3.4e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK57545.1 - 2.9e-07 30.6 0.0 6.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIK57545.1 - 1.7e-06 27.8 4.9 9.7e-06 25.4 4.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK57545.1 - 4.2e-06 26.7 0.3 1.4e-05 25.0 0.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK57545.1 - 0.00016 21.5 5.5 0.00045 20.0 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK57545.1 - 0.00028 20.8 3.6 0.0007 19.5 3.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK57545.1 - 0.00052 20.3 5.8 0.00058 20.1 2.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK57545.1 - 0.00057 19.7 2.4 0.00057 19.7 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK57545.1 - 0.0011 19.0 2.7 0.0011 19.0 2.7 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 KIK57545.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Rad50_zn_hook PF04423.14 KIK57545.1 - 0.025 14.4 0.3 1.6 8.6 0.0 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif FYVE PF01363.21 KIK57545.1 - 0.029 14.5 1.3 0.057 13.6 1.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 KIK57545.1 - 0.38 11.0 1.8 5.1 7.4 0.5 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 KIK57545.1 - 0.53 10.2 8.2 20 5.2 0.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.7 KIK57545.1 - 2.1 8.5 4.1 23 5.1 4.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon Pox_Ag35 PF03286.14 KIK57545.1 - 6.3 6.5 10.0 2.4 7.9 7.1 1.8 1 1 1 2 2 2 0 Pox virus Ag35 surface protein HAD_2 PF13419.6 KIK57546.1 - 2.4e-13 50.6 0.0 3.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK57546.1 - 2.4e-05 24.8 0.0 0.0017 18.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK57546.1 - 0.0077 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ntox35 PF15534.6 KIK57546.1 - 0.099 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 35 NAD_Gly3P_dh_N PF01210.23 KIK57547.1 - 3e-43 147.5 0.0 4.4e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KIK57547.1 - 2.2e-42 144.7 0.0 3.1e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KIK57547.1 - 0.0013 19.2 0.2 2.8 8.6 0.1 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KIK57547.1 - 0.011 15.6 2.0 0.16 11.8 0.4 2.3 1 1 1 2 2 2 0 Rossmann-like domain Pyr_redox_2 PF07992.14 KIK57547.1 - 0.17 11.1 0.0 2.8 7.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_3_C PF01915.22 KIK57548.1 - 2.4e-46 158.2 0.0 4.3e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK57548.1 - 6.4e-43 147.3 0.0 1.2e-42 146.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK57548.1 - 2.5e-18 65.9 0.0 4.3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CD20 PF04103.15 KIK57548.1 - 2.9 8.0 8.9 24 5.0 7.5 2.3 2 0 0 2 2 2 0 CD20-like family adh_short PF00106.25 KIK57549.1 - 3.9e-36 124.3 0.1 9.9e-36 123.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57549.1 - 8.7e-34 117.1 0.1 1.1e-33 116.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK57549.1 - 5.2e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK57549.1 - 0.0032 17.0 0.0 0.0076 15.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK57549.1 - 0.013 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KIK57549.1 - 0.039 14.4 0.2 0.1 13.1 0.1 1.9 1 1 1 2 2 2 0 Putative NAD(P)-binding RmlD_sub_bind PF04321.17 KIK57549.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIK57549.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIK57549.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UQ_con PF00179.26 KIK57550.1 - 1.9e-38 131.3 0.0 2.9e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mucin PF01456.17 KIK57550.1 - 4.8 7.2 19.7 12 5.8 19.7 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM251 PF15190.6 KIK57552.1 - 0.077 13.0 2.8 0.05 13.5 1.8 1.3 1 1 0 1 1 1 0 Transmembrane protein 251 AAA_16 PF13191.6 KIK57553.1 - 0.0004 20.8 0.0 0.0066 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 KIK57553.1 - 0.029 14.4 0.1 0.097 12.7 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK57553.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KIK57553.1 - 0.04 13.5 1.0 5 6.7 0.2 3.1 3 1 0 3 3 3 0 Ras family RRP36 PF06102.12 KIK57553.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 NB-ARC PF00931.22 KIK57553.1 - 0.26 10.4 1.2 0.51 9.5 0.3 2.0 2 1 0 2 2 2 0 NB-ARC domain TPR_10 PF13374.6 KIK57554.1 - 2.5e-116 376.9 14.8 1.4e-08 34.3 0.5 14.0 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_12 PF13424.6 KIK57554.1 - 3e-102 335.0 27.6 3.3e-14 52.9 0.0 10.0 3 3 8 11 11 11 11 Tetratricopeptide repeat TPR_8 PF13181.6 KIK57554.1 - 1.5e-25 87.2 44.3 0.0035 17.5 0.1 13.6 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK57554.1 - 5.5e-24 85.2 27.7 7.3e-10 38.7 1.6 5.2 1 1 3 4 4 4 4 MalT-like TPR region TPR_17 PF13431.6 KIK57554.1 - 2.3e-23 80.8 18.9 0.19 12.1 0.1 13.1 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_7 PF13176.6 KIK57554.1 - 4e-20 70.3 24.1 0.27 11.4 0.0 13.1 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK57554.1 - 9e-20 69.1 34.9 0.046 13.8 0.1 13.5 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK57554.1 - 6.2e-19 67.0 29.5 0.12 12.2 0.1 12.9 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_4 PF07721.14 KIK57554.1 - 1.4e-09 37.7 0.0 5.7 7.9 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK57554.1 - 5.2e-07 30.2 0.6 39 5.0 0.0 8.7 10 2 0 10 10 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK57554.1 - 8.2e-07 29.4 34.0 0.96 10.0 0.4 11.0 2 2 10 13 13 13 2 Tetratricopeptide repeat PPR PF01535.20 KIK57554.1 - 1.5e-06 28.0 14.4 14 6.2 0.0 11.1 13 0 0 13 13 13 0 PPR repeat TPR_14 PF13428.6 KIK57554.1 - 0.00083 20.0 10.8 60 4.8 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat HpaB_N PF11794.8 KIK57554.1 - 0.0032 17.2 0.0 0.96 9.1 0.0 3.3 1 1 2 3 3 3 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TPR_3 PF07720.12 KIK57554.1 - 0.15 12.1 18.8 11 6.1 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK57554.1 - 0.4 10.9 23.1 7.1 6.9 0.1 7.8 4 3 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 MCPVI PF02993.14 KIK57554.1 - 1.6 8.5 12.8 13 5.5 0.1 5.8 2 1 5 9 9 9 0 Minor capsid protein VI PAP2 PF01569.21 KIK57555.1 - 2.6e-18 66.1 5.6 2.6e-18 66.1 5.6 1.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KIK57555.1 - 0.0038 16.9 9.5 0.0064 16.2 9.5 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KIK57555.1 - 1.4 9.5 11.0 0.28 11.7 6.5 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Ndc1_Nup PF09531.10 KIK57556.1 - 1.7 7.2 9.0 1.9 7.1 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_Tyr PF07714.17 KIK57557.1 - 5.4e-42 143.9 0.0 8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK57557.1 - 1.5e-29 103.2 0.0 3.4e-29 102.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain PH_10 PF15411.6 KIK57557.1 - 1.6e-06 28.4 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KIK57557.1 - 4.1e-05 23.9 2.3 7.6e-05 23.0 2.3 1.4 1 0 0 1 1 1 1 RhoGEF domain Kdo PF06293.14 KIK57557.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK57557.1 - 0.049 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK57557.1 - 0.054 12.3 0.1 0.083 11.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KIK57557.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 RIO1 family CDC24 PF06395.11 KIK57557.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 CDC24 Calponin AA_permease PF00324.21 KIK57558.1 - 2.6e-110 369.3 32.3 3.1e-110 369.0 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK57558.1 - 7.5e-33 114.0 32.2 8.9e-33 113.7 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease Orf78 PF06024.12 KIK57558.1 - 0.32 11.3 3.8 22 5.4 0.1 3.5 3 0 0 3 3 3 0 Orf78 (ac78) Na_Ala_symp PF01235.17 KIK57558.1 - 1 8.6 16.5 0.45 9.8 5.8 2.4 2 1 0 2 2 2 0 Sodium:alanine symporter family Adeno_E3_CR2 PF02439.15 KIK57558.1 - 7.2 6.5 8.8 0.23 11.2 0.4 2.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 KIK57559.1 - 0.048 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Acetyltransf_1 PF00583.25 KIK57561.1 - 3.7e-16 59.4 0.0 4.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK57561.1 - 4e-10 39.7 0.1 4.5e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK57561.1 - 2.1e-08 34.5 0.0 2.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK57561.1 - 6.6e-07 29.2 0.1 9.3e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KIK57561.1 - 0.00055 19.5 0.1 0.00061 19.3 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KIK57561.1 - 0.0033 17.4 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Herpes_UL47 PF03362.13 KIK57561.1 - 0.046 12.5 0.1 0.058 12.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein EGL-1 PF11430.8 KIK57561.1 - 0.15 12.0 0.5 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 Programmed cell death activator EGL-1 Amidohydro_2 PF04909.14 KIK57563.1 - 6.4e-24 85.2 0.0 9.1e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Lactamase_B PF00753.27 KIK57565.1 - 1.8e-09 37.9 0.2 5.7e-09 36.3 0.3 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK57565.1 - 0.011 15.2 0.2 0.021 14.3 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain stn_TNFRSF12A PF12191.8 KIK57566.1 - 0.043 14.0 0.1 0.15 12.3 0.0 1.8 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF5134 PF17197.4 KIK57566.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) SKG6 PF08693.10 KIK57566.1 - 0.15 11.5 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2273 PF10031.9 KIK57567.1 - 0.019 15.0 2.4 0.039 14.0 2.4 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Mid2 PF04478.12 KIK57567.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 KIK57567.1 - 0.17 10.7 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4328 PF14219.6 KIK57568.1 - 0.0034 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) DUF4448 PF14610.6 KIK57568.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4064 PF13273.6 KIK57568.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) FixQ PF05545.11 KIK57568.1 - 0.092 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Herpes_gE PF02480.16 KIK57568.1 - 0.12 11.1 0.2 0.42 9.3 0.0 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E PPR PF01535.20 KIK57569.1 - 0.053 13.8 0.1 19 5.8 0.0 2.7 2 0 0 2 2 2 0 PPR repeat eIF2_C PF09173.11 KIK57571.1 - 7.3e-35 119.1 0.6 1.7e-34 117.9 0.6 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KIK57571.1 - 6.6e-20 71.5 1.6 1.2e-18 67.4 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIK57571.1 - 1.4e-11 44.6 1.4 1.9e-11 44.2 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KIK57571.1 - 0.005 16.8 0.9 0.029 14.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KIK57571.1 - 0.015 15.3 1.6 0.022 14.7 0.2 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KIK57571.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Nucleoporin_FG2 PF15967.5 KIK57572.1 - 0.47 8.9 4.6 0.45 9.0 4.6 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region Bap31 PF05529.12 KIK57573.1 - 5.8e-43 146.0 3.3 7.2e-43 145.7 3.3 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KIK57573.1 - 3.7e-09 36.4 6.3 6.1e-09 35.8 6.3 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 KIK57573.1 - 0.018 15.2 1.2 0.018 15.2 1.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper CorA PF01544.18 KIK57574.1 - 0.0019 17.6 1.3 0.0019 17.6 1.3 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF1133 PF06576.11 KIK57574.1 - 0.026 13.9 0.0 0.083 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1133) CAMP_factor PF07373.11 KIK57574.1 - 0.32 10.6 5.8 0.83 9.2 0.4 3.2 1 1 2 3 3 3 0 CAMP factor (Cfa) Sec34 PF04136.15 KIK57574.1 - 0.35 10.8 4.3 2.2 8.1 0.2 3.8 5 0 0 5 5 5 0 Sec34-like family DivIC PF04977.15 KIK57574.1 - 0.35 10.7 2.5 1.2 9.0 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator FliJ PF02050.16 KIK57574.1 - 3.6 7.8 7.4 0.76 10.0 0.1 3.3 4 0 0 4 4 4 0 Flagellar FliJ protein DUF948 PF06103.11 KIK57576.1 - 0.00026 21.2 6.4 4.9 7.5 0.1 5.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KIK57576.1 - 0.0047 17.3 5.4 38 4.8 0.1 5.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KIK57576.1 - 0.01 15.8 11.9 0.098 12.7 0.4 4.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 KIK57576.1 - 0.034 13.6 13.3 0.5 9.7 0.8 3.9 2 2 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus DUF5082 PF16888.5 KIK57576.1 - 0.064 13.5 16.0 0.97 9.7 0.2 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 KIK57576.1 - 0.11 12.4 10.6 4.9 7.1 0.2 4.6 5 0 0 5 5 4 0 Prefoldin subunit TMP_2 PF06791.13 KIK57576.1 - 0.17 11.5 4.1 3.1 7.4 1.2 2.8 2 0 0 2 2 2 0 Prophage tail length tape measure protein BLOC1_2 PF10046.9 KIK57576.1 - 0.21 11.9 12.5 0.71 10.2 1.0 5.1 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.21 KIK57576.1 - 0.3 10.9 8.9 13 5.5 0.0 4.2 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 KIK57576.1 - 0.33 11.5 11.3 1.6 9.3 0.4 4.0 4 1 0 4 4 3 0 Protein of unknown function DUF16 FliJ PF02050.16 KIK57576.1 - 0.39 10.9 9.6 8.5 6.6 0.4 4.3 4 0 0 4 4 4 0 Flagellar FliJ protein DivIC PF04977.15 KIK57576.1 - 0.54 10.1 6.3 9.3 6.1 0.0 4.1 5 0 0 5 5 5 0 Septum formation initiator AAA_32 PF13654.6 KIK57576.1 - 0.57 8.9 5.0 3 6.5 0.2 2.7 3 0 0 3 3 3 0 AAA domain CSN5_C PF18323.1 KIK57576.1 - 0.66 10.9 3.1 28 5.7 0.1 3.0 3 0 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain MbeD_MobD PF04899.12 KIK57576.1 - 0.69 10.1 3.4 2.9 8.1 0.1 3.1 3 0 0 3 3 2 0 MbeD/MobD like TMPIT PF07851.13 KIK57576.1 - 1.1 8.5 7.9 3.5 6.8 0.1 3.2 4 0 0 4 4 4 0 TMPIT-like protein DUF3450 PF11932.8 KIK57576.1 - 1.1 8.6 15.0 0.33 10.2 0.2 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3450) Med9 PF07544.13 KIK57576.1 - 1.1 9.4 9.6 3 8.0 0.2 4.0 5 1 0 5 5 3 0 RNA polymerase II transcription mediator complex subunit 9 Mt_ATP-synt_D PF05873.12 KIK57576.1 - 1.2 9.0 8.4 3.5 7.4 0.7 4.0 5 0 0 5 5 4 0 ATP synthase D chain, mitochondrial (ATP5H) Mod_r PF07200.13 KIK57576.1 - 1.3 9.1 11.8 4.3 7.4 0.1 4.3 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 KIK57576.1 - 1.7 8.8 10.6 0.31 11.2 0.5 4.2 5 0 0 5 5 4 0 Intraflagellar transport complex B, subunit 20 Flagellar_rod PF05149.12 KIK57576.1 - 1.9 7.9 6.0 17 4.7 0.1 3.2 4 0 0 4 4 4 0 Paraflagellar rod protein Spectrin PF00435.21 KIK57576.1 - 1.9 9.0 11.0 9.2 6.8 0.2 4.7 4 2 1 5 5 4 0 Spectrin repeat TMF_TATA_bd PF12325.8 KIK57576.1 - 2.5 8.3 9.2 3.6 7.8 0.1 4.3 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding TACC_C PF05010.14 KIK57576.1 - 2.6 7.8 8.0 3.2 7.5 1.1 3.3 3 1 0 3 3 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Ead_Ea22 PF13935.6 KIK57576.1 - 3.6 8.3 7.2 7.1 7.3 0.6 3.3 4 0 0 4 4 3 0 Ead/Ea22-like protein Baculo_PEP_C PF04513.12 KIK57576.1 - 3.7 7.6 20.3 4.2 7.4 8.5 5.1 3 2 1 5 5 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 KIK57576.1 - 3.8 7.9 15.4 0.12 12.7 0.3 4.6 3 1 1 4 4 4 0 Syntaxin-like protein Prefoldin_2 PF01920.20 KIK57576.1 - 4.2 7.4 11.5 13 5.8 1.1 4.7 5 0 0 5 5 5 0 Prefoldin subunit DUF4200 PF13863.6 KIK57576.1 - 4.2 7.8 13.1 1.1 9.7 1.8 4.1 5 0 0 5 5 4 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 KIK57576.1 - 5.2 7.1 18.6 32 4.5 0.5 5.5 3 2 0 4 4 4 0 Laminin Domain II Rootletin PF15035.6 KIK57576.1 - 5.7 6.9 6.7 10 6.1 1.5 3.3 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Seryl_tRNA_N PF02403.22 KIK57576.1 - 5.9 7.2 10.6 11 6.3 1.0 4.5 3 1 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KIK57576.1 - 7.3 7.1 17.0 14 6.2 0.3 5.0 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Taxilin PF09728.9 KIK57576.1 - 7.5 5.6 11.4 1.1 8.3 1.9 3.1 4 0 0 4 4 4 0 Myosin-like coiled-coil protein DNA_repr_REX1B PF14966.6 KIK57576.1 - 7.6 7.3 6.6 20 5.9 0.1 3.9 4 0 0 4 4 3 0 DNA repair REX1-B THOC7 PF05615.13 KIK57576.1 - 9.6 6.5 9.2 25 5.2 0.1 3.9 3 1 1 4 4 4 0 Tho complex subunit 7 DUF2203 PF09969.9 KIK57576.1 - 9.6 7.0 8.5 41 4.9 0.3 4.4 3 1 3 6 6 6 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.12 KIK57577.1 - 0.00025 21.4 14.5 0.32 11.5 0.1 4.7 3 1 1 4 4 4 2 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KIK57577.1 - 0.00049 20.3 4.9 1 9.7 0.0 4.7 5 0 0 5 5 4 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KIK57577.1 - 0.00092 19.2 13.2 0.89 9.6 0.3 4.4 3 1 0 4 4 4 2 Laminin Domain II Med9 PF07544.13 KIK57577.1 - 0.0045 17.0 5.1 0.095 12.8 0.4 3.3 3 1 1 4 4 3 1 RNA polymerase II transcription mediator complex subunit 9 Sec34 PF04136.15 KIK57577.1 - 0.013 15.3 6.0 1.9 8.4 0.4 3.9 3 0 0 3 3 3 0 Sec34-like family HSBP1 PF06825.12 KIK57577.1 - 0.024 14.5 0.5 0.45 10.4 0.0 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 MbeD_MobD PF04899.12 KIK57577.1 - 0.026 14.6 0.5 16 5.7 0.0 3.2 2 0 0 2 2 2 0 MbeD/MobD like Prominin PF05478.11 KIK57577.1 - 0.041 11.9 2.4 2.6 5.9 0.0 3.1 3 0 0 3 3 3 0 Prominin Ax_dynein_light PF10211.9 KIK57577.1 - 0.048 13.6 0.7 0.37 10.7 0.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain CorA PF01544.18 KIK57577.1 - 0.057 12.7 6.8 0.13 11.5 1.1 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein FliJ PF02050.16 KIK57577.1 - 0.061 13.6 10.9 0.68 10.2 0.6 4.5 6 0 0 6 6 5 0 Flagellar FliJ protein DUF4337 PF14235.6 KIK57577.1 - 0.078 13.1 0.2 0.078 13.1 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2935 PF11155.8 KIK57577.1 - 0.086 13.2 0.4 23 5.3 0.2 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) MCPsignal PF00015.21 KIK57577.1 - 0.096 12.5 9.4 19 5.0 0.0 4.6 4 1 1 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 KIK57577.1 - 0.098 12.7 6.9 2.1 8.4 0.5 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) TMP_2 PF06791.13 KIK57577.1 - 0.11 12.2 4.6 0.12 12.0 1.1 2.7 3 0 0 3 3 3 0 Prophage tail length tape measure protein DUF16 PF01519.16 KIK57577.1 - 0.14 12.6 6.2 5.9 7.4 0.6 3.8 3 1 0 3 3 3 0 Protein of unknown function DUF16 Spc7 PF08317.11 KIK57577.1 - 0.17 10.7 5.7 7.8 5.3 0.6 3.6 3 1 0 4 4 4 0 Spc7 kinetochore protein RPW8 PF05659.11 KIK57577.1 - 0.37 10.5 4.5 26 4.5 0.0 3.9 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Snapin_Pallidin PF14712.6 KIK57577.1 - 0.38 11.2 10.0 14 6.2 0.3 4.2 4 0 0 4 4 4 0 Snapin/Pallidin FlaC_arch PF05377.11 KIK57577.1 - 0.39 11.1 5.0 35 4.9 0.2 4.0 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) FliD_C PF07195.12 KIK57577.1 - 0.39 10.1 6.3 7.2 6.0 0.2 3.1 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Flagellar_rod PF05149.12 KIK57577.1 - 0.51 9.8 3.6 18 4.7 1.5 2.5 2 0 0 2 2 2 0 Paraflagellar rod protein LZ3wCH PF18517.1 KIK57577.1 - 0.65 10.1 5.6 16 5.7 1.4 3.0 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DHR10 PF18595.1 KIK57577.1 - 0.65 10.1 8.9 3.9 7.6 1.6 4.2 4 1 0 4 4 4 0 Designed helical repeat protein 10 domain Mod_r PF07200.13 KIK57577.1 - 0.71 10.0 10.9 1.4 9.0 0.6 3.5 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF4618 PF15397.6 KIK57577.1 - 0.98 8.8 5.5 0.37 10.2 0.2 2.5 3 1 0 3 3 2 0 Domain of unknown function (DUF4618) DUF5082 PF16888.5 KIK57577.1 - 1.3 9.3 10.8 16 5.8 0.6 4.0 4 1 0 4 4 3 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 KIK57577.1 - 1.6 8.7 14.8 1.6 8.6 0.5 5.0 4 1 1 6 6 5 0 Prefoldin subunit TBK1_CCD1 PF18394.1 KIK57577.1 - 1.8 8.1 7.1 3.1 7.3 0.7 2.8 2 1 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 Taxilin PF09728.9 KIK57577.1 - 2.5 7.2 7.5 1.7 7.8 2.4 2.5 3 0 0 3 3 2 0 Myosin-like coiled-coil protein Seryl_tRNA_N PF02403.22 KIK57577.1 - 2.6 8.3 7.0 1.3 9.3 0.4 3.5 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain PhaP_Bmeg PF09602.10 KIK57577.1 - 2.6 7.9 8.8 0.4 10.6 0.7 3.1 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CC2-LZ PF16516.5 KIK57577.1 - 2.8 8.4 5.0 7.2 7.0 0.2 3.4 5 0 0 5 5 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BLOC1_2 PF10046.9 KIK57577.1 - 3.7 7.9 15.4 5.3 7.4 2.2 4.7 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KIK57577.1 - 3.7 7.7 12.4 8.3 6.6 1.2 4.5 5 1 0 5 5 4 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 KIK57578.1 - 6.3e-09 35.5 0.0 3.1e-08 33.3 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KIK57579.1 - 3e-13 49.4 0.1 6.5e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4035 PF13227.6 KIK57581.1 - 0.083 12.6 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) LRS4 PF10422.9 KIK57582.1 - 0.023 14.3 0.2 0.046 13.3 0.2 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Med9 PF07544.13 KIK57582.1 - 0.27 11.3 4.8 12 6.0 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Wtap PF17098.5 KIK57582.1 - 0.3 11.0 3.6 0.97 9.3 0.0 3.0 3 0 0 3 3 3 0 WTAP/Mum2p family Collagen_mid PF15984.5 KIK57582.1 - 0.35 10.6 2.0 0.87 9.3 0.4 2.4 3 1 0 3 3 3 0 Bacterial collagen, middle region CdvA PF18822.1 KIK57582.1 - 4.6 7.1 7.8 25 4.7 0.9 3.8 3 1 1 4 4 4 0 CdvA-like coiled-coil domain Thaumatin PF00314.17 KIK57583.1 - 4e-69 232.5 11.2 4.6e-69 232.3 11.2 1.0 1 0 0 1 1 1 1 Thaumatin family RINGv PF12906.7 KIK57584.1 - 6.8e-06 26.1 6.8 1.1e-05 25.4 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KIK57584.1 - 0.062 13.5 3.2 0.12 12.6 3.2 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 KIK57584.1 - 0.078 13.3 7.2 0.12 12.7 7.2 1.3 1 0 0 1 1 1 0 Ring finger domain PHD_Oberon PF07227.11 KIK57584.1 - 0.38 10.6 1.5 0.6 10.0 1.5 1.2 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein SNARE_assoc PF09335.11 KIK57584.1 - 2 8.9 9.7 0.5 10.9 1.9 2.6 3 0 0 3 3 3 0 SNARE associated Golgi protein PHD_4 PF16866.5 KIK57584.1 - 4.3 7.5 7.1 7.7 6.7 6.9 1.5 1 1 0 1 1 1 0 PHD-finger Methyltransf_25 PF13649.6 KIK57587.1 - 1e-08 35.8 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57587.1 - 0.00027 21.5 0.0 0.00045 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57587.1 - 0.00036 19.9 0.0 0.00067 19.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIK57587.1 - 0.0012 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57587.1 - 0.0061 16.4 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK57587.1 - 0.0077 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAE2 PF08573.10 KIK57588.1 - 4.8e-18 66.3 2.7 4.8e-18 66.3 2.7 4.4 4 0 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SKA2 PF16740.5 KIK57588.1 - 0.61 9.9 6.5 0.14 11.9 1.5 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TPR_MLP1_2 PF07926.12 KIK57588.1 - 6.2 6.9 17.6 0.028 14.5 5.9 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Methyltransf_23 PF13489.6 KIK57589.1 - 2.1e-13 50.5 0.0 3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57589.1 - 9.9e-09 35.8 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57589.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK57589.1 - 0.00082 20.0 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK57589.1 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KIK57589.1 - 0.12 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57590.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57590.1 - 0.00047 20.8 0.0 0.00097 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57590.1 - 0.054 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57591.1 - 4.9e-15 55.8 0.0 7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57591.1 - 5.6e-09 36.6 0.0 9.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57591.1 - 9.4e-05 23.0 0.0 0.00015 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57591.1 - 0.00059 19.2 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK57591.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KIK57591.1 - 0.012 16.4 0.0 0.023 15.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57591.1 - 0.022 14.6 0.0 0.04 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57592.1 - 3e-15 56.4 0.0 8.8e-15 54.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57592.1 - 4.3e-09 37.0 0.0 8.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57592.1 - 0.00017 22.2 0.0 0.00033 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57592.1 - 0.00053 19.4 0.0 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK57592.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK57592.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KIK57592.1 - 0.044 14.5 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57593.1 - 7e-12 45.5 0.0 9.9e-12 45.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57593.1 - 5.4e-08 33.4 0.0 9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57593.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KIK57593.1 - 0.0074 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KIK57593.1 - 0.012 16.2 0.0 0.02 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57594.1 - 5.9e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57594.1 - 6e-07 30.1 0.0 1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK57594.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF1254 PF06863.12 KIK57594.1 - 0.13 12.3 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1254) UCH PF00443.29 KIK57595.1 - 1.9e-42 145.6 0.0 5e-42 144.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK57595.1 - 1.9e-08 34.3 1.5 1.9e-05 24.4 1.5 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIK57595.1 - 0.0025 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Glyco_trans_2_3 PF13632.6 KIK57596.1 - 2.1e-16 60.4 1.1 2.1e-16 60.4 1.1 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK57596.1 - 4.8e-16 59.3 0.0 7.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK57596.1 - 9.7e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KIK57596.1 - 1.9e-09 36.6 0.4 1.2e-05 24.0 0.5 2.3 1 1 1 2 2 2 2 Cellulose synthase Glyco_transf_21 PF13506.6 KIK57596.1 - 6.7e-07 28.9 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 UPF0016 PF01169.19 KIK57598.1 - 0.032 14.6 1.7 0.11 12.9 1.7 1.9 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 Peroxidase_2 PF01328.17 KIK57599.1 - 3e-49 168.1 0.0 3.6e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 FAD_binding_3 PF01494.19 KIK57600.1 - 1.3e-09 37.8 0.0 1.8e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Dicty_REP PF05086.12 KIK57601.1 - 1.2 7.1 6.6 1.3 6.9 6.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Thaumatin PF00314.17 KIK57603.1 - 4e-53 180.2 6.3 2.7e-52 177.5 6.3 1.9 1 1 0 1 1 1 1 Thaumatin family ASF1_hist_chap PF04729.13 KIK57604.1 - 1.5e-59 200.4 0.0 1.8e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGEF PF00617.19 KIK57605.1 - 1e-27 97.5 0.1 1.2e-26 94.0 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIK57605.1 - 3.4e-08 33.6 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SET PF00856.28 KIK57606.1 - 7.9e-12 45.9 0.0 1.4e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 KIK57606.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain WD40 PF00400.32 KIK57607.1 - 1.4e-32 111.2 12.9 8.2e-13 48.6 0.3 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57607.1 - 5.2e-15 55.5 0.0 0.0012 19.2 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK57607.1 - 1.7e-09 37.1 0.1 0.053 12.5 0.0 3.0 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK57607.1 - 7.5e-06 24.5 0.0 0.0022 16.4 0.0 2.4 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK57607.1 - 7.8e-06 25.7 0.0 0.34 10.9 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK57607.1 - 7.7e-05 22.6 0.4 0.00055 19.8 0.4 2.5 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain PQQ PF01011.21 KIK57607.1 - 0.00029 20.6 0.3 0.62 10.1 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat Nup160 PF11715.8 KIK57607.1 - 0.0014 17.4 1.6 2.9 6.4 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK57607.1 - 0.0024 18.3 0.4 28 5.3 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain DUF4072 PF13284.6 KIK57607.1 - 0.0032 17.9 0.6 7.5 7.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4072) PQQ_2 PF13360.6 KIK57607.1 - 0.0037 16.9 3.3 0.025 14.2 1.3 2.0 1 1 0 2 2 2 1 PQQ-like domain DUF1707 PF08044.11 KIK57607.1 - 0.0089 16.1 0.0 5.5 7.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1707) DPPIV_N PF00930.21 KIK57607.1 - 0.058 12.1 0.0 0.86 8.3 0.0 2.2 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_like PF17005.5 KIK57607.1 - 0.083 12.2 0.0 25 4.0 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain WD40_3 PF15911.5 KIK57607.1 - 0.14 12.2 0.1 18 5.5 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KIK57607.1 - 1.3 8.8 4.2 49 3.7 0.1 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KIK57608.1 - 8.5e-05 23.0 0.0 0.00012 22.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK57608.1 - 0.00011 22.1 0.1 0.00019 21.4 0.1 1.4 1 1 0 1 1 1 1 NTPase NACHT PF05729.12 KIK57608.1 - 0.00046 20.1 0.2 0.00067 19.6 0.2 1.4 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 KIK57608.1 - 0.0006 19.7 0.2 0.0011 18.9 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK57608.1 - 0.0014 19.0 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK57608.1 - 0.0029 16.8 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK57608.1 - 0.0074 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KIK57608.1 - 0.0077 16.8 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK57608.1 - 0.011 15.9 0.1 0.013 15.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK57608.1 - 0.028 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK57608.1 - 0.028 13.9 0.3 0.063 12.8 0.1 1.5 1 1 1 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KIK57608.1 - 0.034 13.4 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KIK57608.1 - 0.041 13.9 0.3 0.071 13.2 0.3 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KIK57608.1 - 0.053 13.2 0.1 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Thymidylate kinase PhoH PF02562.16 KIK57608.1 - 0.059 12.8 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KIK57608.1 - 0.064 13.5 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KIK57608.1 - 0.093 12.0 0.0 10 5.3 0.0 2.1 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Cytidylate_kin PF02224.18 KIK57608.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 KIK57608.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK57610.1 - 0.00026 21.5 0.0 0.00028 21.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK57610.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK57610.1 - 0.036 14.6 0.2 0.044 14.3 0.2 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK57610.1 - 0.091 12.8 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KIK57610.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KIK57610.1 - 0.29 9.7 0.1 0.29 9.7 0.1 1.0 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.17 KIK57612.1 - 3.4e-07 30.4 0.3 5.2e-07 29.8 0.3 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Antimicrobial19 PF08225.11 KIK57612.1 - 0.22 11.2 1.5 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide DUF4364 PF14277.6 KIK57613.1 - 0.17 11.7 1.1 0.39 10.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) DUF4407 PF14362.6 KIK57613.1 - 3 7.1 8.8 6.7 6.0 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 KIK57615.1 - 8.3e-62 203.7 26.0 2.7e-12 47.0 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57615.1 - 3.9e-22 78.3 0.0 0.0048 17.2 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK57615.1 - 4.8e-12 45.5 0.1 0.77 9.8 0.0 5.3 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK57615.1 - 1e-11 44.4 1.4 0.25 10.3 0.0 5.3 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK57615.1 - 2.3e-08 33.6 4.8 1.1 9.3 0.0 6.0 6 0 0 6 6 6 1 PQQ enzyme repeat Gmad1 PF10647.9 KIK57615.1 - 2.8e-08 33.8 1.4 0.027 14.2 0.1 4.5 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK57615.1 - 3.2e-06 26.1 3.5 3.6 6.1 0.0 5.7 3 1 1 6 6 6 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK57615.1 - 1.5e-05 24.7 12.5 0.11 12.1 0.8 3.2 3 1 0 3 3 3 3 PQQ-like domain DUF4072 PF13284.6 KIK57615.1 - 7.8e-05 23.0 2.5 22 5.6 0.0 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF4072) DUF1707 PF08044.11 KIK57615.1 - 0.00025 21.0 0.0 25 5.0 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) WD40_3 PF15911.5 KIK57615.1 - 0.00032 20.6 2.9 27 4.9 0.0 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat Frtz PF11768.8 KIK57615.1 - 0.00047 18.6 0.0 1.2 7.3 0.0 4.1 3 2 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz DPPIV_N PF00930.21 KIK57615.1 - 0.00087 18.1 0.0 5.4 5.7 0.0 4.1 1 1 3 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region NifZ PF04319.13 KIK57615.1 - 0.015 15.1 0.3 6.9 6.5 0.0 3.8 3 1 1 4 4 4 0 NifZ domain Peptidase_S9_N PF02897.15 KIK57615.1 - 0.019 13.8 0.0 5.7 5.6 0.0 3.3 2 1 2 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Me-amine-dh_H PF06433.11 KIK57615.1 - 0.024 13.5 0.0 5.1 5.8 0.0 2.7 1 1 2 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) DUF3313 PF11769.8 KIK57615.1 - 0.087 12.6 0.4 4.9 6.9 0.0 3.4 5 1 0 5 5 5 0 Protein of unknown function (DUF3313) PQQ_3 PF13570.6 KIK57615.1 - 0.13 12.8 13.4 9.2 6.9 0.8 5.1 4 1 1 5 5 5 0 PQQ-like domain BAT PF15915.5 KIK57615.1 - 0.27 11.1 1.8 5.6 6.8 0.1 3.1 2 2 2 4 4 4 0 GAF and HTH_10 associated domain Proteasome_A_N PF10584.9 KIK57615.1 - 0.53 10.0 8.9 95 2.8 0.1 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CHAP PF05257.16 KIK57615.1 - 0.93 10.1 9.4 27 5.4 0.3 4.4 2 1 1 4 4 4 0 CHAP domain NACHT PF05729.12 KIK57616.1 - 6.1e-10 39.3 0.4 1.4e-09 38.0 0.4 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK57616.1 - 1.8e-06 28.5 0.0 2.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK57616.1 - 0.0002 21.3 0.1 0.00065 19.6 0.0 1.8 2 0 0 2 2 2 1 NTPase AAA PF00004.29 KIK57616.1 - 0.00041 20.8 0.1 0.00097 19.6 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK57616.1 - 0.00075 19.4 0.2 0.0016 18.4 0.2 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK57616.1 - 0.0015 17.8 0.4 0.0028 16.9 0.4 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK57616.1 - 0.0069 16.9 0.0 0.0098 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK57616.1 - 0.0081 16.5 0.1 0.026 14.9 0.1 1.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KIK57616.1 - 0.027 14.6 0.2 0.034 14.3 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK57616.1 - 0.033 14.5 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK57616.1 - 0.041 14.2 1.0 0.29 11.4 1.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK57616.1 - 0.053 12.7 0.2 0.089 12.0 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK57616.1 - 0.061 13.4 0.1 12 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIK57616.1 - 0.066 12.7 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KIK57616.1 - 0.071 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase CbiA PF01656.23 KIK57616.1 - 0.097 12.7 0.5 0.27 11.3 0.5 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 KIK57616.1 - 0.13 11.6 0.0 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KIK57616.1 - 0.2 11.3 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK57618.1 - 0.015 15.9 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 ABC transporter SET PF00856.28 KIK57619.1 - 9.5e-09 35.9 0.0 1.7e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 SET domain Retrotran_gag_2 PF14223.6 KIK57620.1 - 4e-14 52.4 0.2 6.4e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1664 PF07889.12 KIK57621.1 - 0.0028 17.7 1.3 0.019 15.0 1.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 KIK57621.1 - 0.019 14.8 0.5 0.032 14.0 0.5 1.4 1 0 0 1 1 1 0 Synaptobrevin Tape_meas_lam_C PF09718.10 KIK57621.1 - 0.029 14.5 8.6 2.6 8.3 0.5 3.6 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoO PF09769.9 KIK57621.1 - 0.054 13.4 0.2 0.61 10.1 0.0 2.4 1 1 2 3 3 3 0 Apolipoprotein O Ribosomal_L12 PF00542.19 KIK57621.1 - 0.067 13.5 1.1 0.24 11.8 0.4 2.3 2 1 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain YtxH PF12732.7 KIK57621.1 - 0.15 12.6 10.4 0.53 10.9 0.5 2.9 2 1 1 3 3 3 0 YtxH-like protein Myb_DNA-bind_2 PF08914.11 KIK57622.1 - 1.9e-09 37.5 3.5 5.6e-09 36.1 3.5 1.9 1 1 0 1 1 1 1 Rap1 Myb domain F-box PF00646.33 KIK57623.1 - 2e-05 24.4 0.4 4.8e-05 23.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK57623.1 - 2e-05 24.4 0.5 5.2e-05 23.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 KIK57624.1 - 4.3e-22 78.4 0.1 6.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK57624.1 - 9.1e-10 38.5 4.5 2e-09 37.4 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHHC PF01529.20 KIK57625.1 - 5e-34 117.3 2.6 5e-34 117.3 2.6 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF35_N PF12172.8 KIK57625.1 - 0.093 12.6 3.4 0.23 11.4 3.4 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Phage_holin_3_6 PF07332.11 KIK57625.1 - 2.5 8.2 7.0 1 9.4 1.0 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FAD_binding_2 PF00890.24 KIK57626.1 - 4.8e-55 187.3 0.5 5.1e-55 187.2 0.5 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK57626.1 - 2.5e-12 47.1 1.3 5.1e-12 46.1 1.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK57626.1 - 1.9e-09 37.1 1.8 1.1e-06 28.0 1.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIK57626.1 - 1.3e-08 34.4 2.2 3.2e-08 33.2 2.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK57626.1 - 4.8e-08 32.8 3.9 2.8e-07 30.2 3.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK57626.1 - 2.6e-05 24.7 2.2 0.0092 16.5 0.5 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK57626.1 - 3.5e-05 23.9 1.6 7.3e-05 22.9 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK57626.1 - 7.1e-05 22.2 1.9 0.00027 20.3 1.4 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK57626.1 - 0.00021 20.1 2.4 0.003 16.3 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIK57626.1 - 0.003 16.8 0.2 0.1 11.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIK57626.1 - 0.0049 16.2 0.7 0.0088 15.4 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIK57626.1 - 0.0061 17.0 0.0 0.056 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KIK57626.1 - 0.0077 15.5 0.7 0.015 14.5 0.7 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KIK57626.1 - 0.017 14.2 0.6 0.031 13.3 0.6 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 KIK57626.1 - 0.032 13.6 0.2 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase CTP_transf_like PF01467.26 KIK57627.1 - 2.6e-08 34.2 0.0 5.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KIK57627.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase Homez PF11569.8 KIK57627.1 - 0.19 11.2 0.0 0.48 9.9 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Glyco_hydro_7 PF00840.20 KIK57628.1 - 2e-197 656.2 14.2 2.4e-197 655.9 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KIK57628.1 - 1.2e-12 47.5 5.2 1.2e-12 47.5 5.2 4.6 5 0 0 5 5 5 1 Fungal cellulose binding domain Trefoil PF00088.18 KIK57628.1 - 0.2 11.6 6.9 2.8 7.9 1.3 3.1 2 0 0 2 2 2 0 Trefoil (P-type) domain Glyco_hydro_7 PF00840.20 KIK57629.1 - 2.3e-199 662.6 16.3 2.7e-199 662.4 16.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Trefoil PF00088.18 KIK57629.1 - 0.38 10.7 6.9 3 7.8 0.4 3.2 3 0 0 3 3 3 0 Trefoil (P-type) domain Ribosomal_L7Ae PF01248.26 KIK57630.1 - 8.4e-26 89.5 0.0 1e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KIK57630.1 - 0.00017 21.4 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KIK57630.1 - 0.0018 18.3 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 UQ_con PF00179.26 KIK57631.1 - 1.9e-48 163.7 0.0 2.1e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK57631.1 - 0.00019 21.1 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIK57631.1 - 0.15 12.3 0.6 0.28 11.5 0.6 1.7 1 1 0 1 1 1 0 RWD domain Mannosyl_trans PF05007.13 KIK57633.1 - 4.4e-72 243.1 14.9 9.3e-72 242.0 14.9 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KIK57633.1 - 1.3e-12 47.5 1.1 1.3e-12 47.5 1.1 2.2 1 1 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KIK57633.1 - 6.4e-07 29.3 7.8 6.4e-07 29.3 7.8 2.4 1 1 1 2 2 2 1 Glycosyltransferase family 87 Arf PF00025.21 KIK57634.1 - 3.8e-67 225.1 0.0 4.2e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK57634.1 - 1.3e-11 44.3 0.0 3.8e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIK57634.1 - 9.6e-11 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KIK57634.1 - 3e-08 33.9 0.0 1.2e-07 32.0 0.0 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIK57634.1 - 1.1e-07 31.9 0.0 1.9e-07 31.2 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KIK57634.1 - 1.2e-06 28.2 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIK57634.1 - 4.6e-05 22.9 0.0 5.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KIK57634.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIK57634.1 - 0.057 13.0 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase_Tyr PF07714.17 KIK57635.1 - 1.1e-28 100.3 0.0 5.9e-21 74.9 0.0 3.4 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KIK57635.1 - 5.9e-27 94.7 0.0 5.5e-21 75.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain DUF4238 PF14022.6 KIK57635.1 - 3.2e-08 33.4 0.0 1.5e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.23 KIK57635.1 - 0.00024 21.1 0.0 0.00098 19.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family SH3_9 PF14604.6 KIK57636.1 - 3.6e-14 52.3 0.1 7.4e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK57636.1 - 4.1e-14 51.9 0.3 9.6e-14 50.7 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.30 KIK57636.1 - 1.6e-12 47.7 0.0 3.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KIK57636.1 - 3.3e-12 46.8 0.3 7.3e-12 45.7 0.3 1.6 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 KIK57636.1 - 3.6e-12 46.2 0.0 6.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KIK57636.1 - 1.7e-08 34.0 0.0 3.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_Ste50p PF09235.10 KIK57636.1 - 0.013 15.7 0.4 0.026 14.8 0.4 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.16 KIK57636.1 - 0.031 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KIK57636.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1980 PF09323.10 KIK57636.1 - 5.5 6.9 8.5 1.5 8.7 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1713 PF08213.11 KIK57638.1 - 3.6e-07 30.0 25.2 5.5e-07 29.4 25.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) zf-C4_Topoisom PF01396.19 KIK57639.1 - 0.016 15.0 0.4 0.038 13.8 0.4 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger WD40 PF00400.32 KIK57640.1 - 1.8e-05 25.4 15.2 0.15 13.0 0.2 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57640.1 - 0.029 14.7 0.0 0.31 11.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cofilin_ADF PF00241.20 KIK57641.1 - 1e-18 67.3 0.0 1.1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.16 KIK57642.1 - 4.8e-24 85.0 21.6 3.4e-19 69.0 10.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 KIK57642.1 - 0.026 13.3 0.4 2.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Reduced folate carrier DUF3270 PF11674.8 KIK57642.1 - 4.3 7.6 7.1 2.3 8.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) PLA2_B PF01735.18 KIK57643.1 - 5.7e-101 338.3 0.0 7.2e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo_endo_phos PF03372.23 KIK57644.1 - 2.7e-07 30.4 0.0 1.1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_CA PF00484.19 KIK57645.1 - 1.9e-40 138.7 0.0 2.8e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L30_N PF08079.12 KIK57646.1 - 5.2e-29 100.3 16.2 5.2e-29 100.3 16.2 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KIK57646.1 - 1.7e-18 66.3 1.2 4e-18 65.0 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KIK57646.1 - 0.043 13.6 0.6 0.98 9.2 0.1 2.4 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter zf-MYND PF01753.18 KIK57647.1 - 2e-09 37.4 14.5 2e-09 37.4 14.5 2.8 4 0 0 4 4 4 1 MYND finger Alpha_GJ PF03229.13 KIK57647.1 - 0.11 13.0 2.4 0.33 11.5 2.4 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J Gly-zipper_YMGG PF13441.6 KIK57647.1 - 0.91 9.3 4.9 0.52 10.1 1.9 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper zf-C6H2 PF15801.5 KIK57647.1 - 2 8.8 15.4 1 9.7 12.8 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Herpes_pp85 PF04637.12 KIK57647.1 - 4 5.7 4.9 6.2 5.1 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Acetyltransf_2 PF00797.17 KIK57648.1 - 1.8e-22 80.3 0.0 1e-19 71.3 0.0 2.1 2 0 0 2 2 2 2 N-acetyltransferase SAICAR_synt PF01259.18 KIK57649.1 - 4.4e-99 331.2 0.0 5.3e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase PABP PF00658.18 KIK57649.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain adh_short_C2 PF13561.6 KIK57651.1 - 3.4e-61 206.8 1.5 4.2e-61 206.5 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK57651.1 - 4.2e-55 186.2 2.0 4.2e-55 186.2 2.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK57651.1 - 2.3e-10 40.7 1.2 3.3e-10 40.2 1.2 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK57651.1 - 0.028 13.6 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK57651.1 - 0.036 13.5 0.3 0.089 12.2 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIK57651.1 - 0.054 13.4 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KIK57652.1 - 2e-29 102.6 37.2 2.7e-21 75.9 6.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK57652.1 - 0.00012 20.6 0.9 0.00012 20.6 0.9 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 KIK57653.1 - 2.1e-08 33.9 4.4 9.2e-08 31.9 4.4 2.2 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK57653.1 - 0.31 11.5 13.6 11 6.6 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK57653.1 - 1.4 8.9 7.9 5.1 7.1 0.3 2.9 2 0 0 2 2 2 0 F-box domain TMEM154 PF15102.6 KIK57654.1 - 0.0051 16.7 0.4 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 TMEM154 protein family BatD PF13584.6 KIK57654.1 - 0.0082 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance RIFIN PF02009.16 KIK57654.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Rifin SIT PF15330.6 KIK57654.1 - 0.023 15.1 0.4 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Saf_2TM PF18303.1 KIK57654.1 - 0.1 12.2 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain TMEM51 PF15345.6 KIK57654.1 - 0.17 11.7 3.8 0.16 11.8 1.7 1.8 1 1 1 2 2 2 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 KIK57654.1 - 0.22 11.5 0.2 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PknG_rubred PF16919.5 KIK57654.1 - 1.5 9.0 6.9 0.36 11.0 2.3 2.3 3 0 0 3 3 3 0 Protein kinase G rubredoxin domain RicinB_lectin_2 PF14200.6 KIK57655.1 - 4.7e-05 24.0 2.0 0.0012 19.5 1.5 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.10 KIK57656.1 - 0.0015 17.9 1.8 0.0032 16.8 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KIK57656.1 - 0.0024 18.3 5.7 0.0024 18.3 5.7 2.3 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amnionless PF14828.6 KIK57656.1 - 0.0043 15.9 0.0 0.006 15.5 0.0 1.1 1 0 0 1 1 1 1 Amnionless TrbC PF04956.13 KIK57656.1 - 0.0056 16.9 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 TrbC/VIRB2 family Mid2 PF04478.12 KIK57656.1 - 0.024 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor BPD_transp_2 PF02653.16 KIK57656.1 - 0.043 13.0 1.6 3 6.9 0.2 2.3 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component CD34_antigen PF06365.12 KIK57656.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 KIK57656.1 - 0.14 13.0 0.0 0.31 11.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TrbL PF04610.14 KIK57656.1 - 0.6 9.8 3.4 1.2 8.9 3.4 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Herpes_gE PF02480.16 KIK57657.1 - 0.0018 17.1 0.1 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK57657.1 - 0.033 15.1 0.0 0.13 13.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 KIK57657.1 - 0.044 13.6 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4233 PF14017.6 KIK57657.1 - 0.044 14.1 2.4 0.76 10.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) BatA PF07584.11 KIK57657.1 - 0.15 12.5 1.1 0.36 11.2 0.1 2.0 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal TMEM154 PF15102.6 KIK57657.1 - 1.1 9.2 3.4 1.4 8.8 0.3 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 KIK57658.1 - 0.076 11.8 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA PF00004.29 KIK57659.1 - 3.5e-14 53.4 0.0 4.8e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 KIK57659.1 - 9.7e-14 51.3 0.0 2.4e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.6 KIK57659.1 - 6.4e-09 36.4 0.0 5.2e-08 33.5 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 KIK57659.1 - 8.7e-06 25.8 0.1 2e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KIK57659.1 - 8.8e-06 26.0 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK57659.1 - 0.0022 18.3 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK57659.1 - 0.028 14.2 2.1 0.038 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK57659.1 - 0.047 13.4 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK57659.1 - 0.067 12.3 0.0 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein PIF1 PF05970.14 KIK57659.1 - 0.095 11.8 0.0 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 PIF1-like helicase NTPase_1 PF03266.15 KIK57659.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 KIK57659.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KIK57659.1 - 0.16 11.8 0.1 1.5 8.6 0.1 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Spore_coat_CotO PF14153.6 KIK57659.1 - 0.68 9.8 12.3 0.4 10.6 9.1 2.2 1 1 1 2 2 2 0 Spore coat protein CotO Snf7 PF03357.21 KIK57660.1 - 2e-21 76.4 2.7 2.6e-21 76.0 2.7 1.1 1 0 0 1 1 1 1 Snf7 ATP-synt_DE_N PF02823.16 KIK57660.1 - 0.11 12.4 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SlyX PF04102.12 KIK57660.1 - 2.1 9.0 5.1 1.8 9.2 0.1 2.9 3 0 0 3 3 3 0 SlyX EphA2_TM PF14575.6 KIK57662.1 - 0.014 16.2 0.0 0.023 15.6 0.0 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK57662.1 - 0.02 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Alpha_GJ PF03229.13 KIK57662.1 - 0.025 15.1 0.7 0.025 15.1 0.7 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF2062 PF09835.9 KIK57662.1 - 0.067 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) PTP_tm PF18861.1 KIK57662.1 - 0.089 12.8 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MGC-24 PF05283.11 KIK57662.1 - 9.5 6.7 9.6 0.36 11.3 0.6 2.3 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HSP9_HSP12 PF04119.12 KIK57663.1 - 1.3e-25 89.6 4.8 1.9e-25 89.0 4.8 1.3 1 0 0 1 1 1 1 Heat shock protein 9/12 HET-s_218-289 PF11558.8 KIK57663.1 - 0.081 13.0 0.7 0.23 11.5 0.5 1.8 1 1 1 2 2 2 0 Het-s 218-289 RicinB_lectin_2 PF14200.6 KIK57664.1 - 3e-06 27.9 2.0 0.0052 17.5 0.1 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ribosomal_L26 PF16906.5 KIK57665.1 - 7.4e-37 125.7 4.6 1.1e-36 125.2 4.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KIK57665.1 - 4.9e-09 35.8 4.1 4.9e-09 35.8 4.1 1.8 2 0 0 2 2 2 1 KOW motif DUF4663 PF15668.5 KIK57665.1 - 0.048 12.7 0.5 0.052 12.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Methyltrans_RNA PF04452.14 KIK57665.1 - 0.085 12.2 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 RNA methyltransferase ATP-synt_D PF01813.17 KIK57666.1 - 4.1e-68 229.1 3.5 5.4e-68 228.7 3.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KIK57666.1 - 0.084 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) TRAPP PF04051.16 KIK57667.1 - 1.9e-35 121.7 0.0 2.3e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_S13 PF00416.22 KIK57668.1 - 1e-22 80.9 0.0 3.9e-12 46.7 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 IMS_HHH PF11798.8 KIK57668.1 - 0.064 13.6 0.0 0.83 10.1 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif SieB PF14163.6 KIK57668.1 - 0.17 11.3 0.1 0.57 9.7 0.0 2.0 2 1 0 2 2 2 0 Super-infection exclusion protein B XAP5 PF04921.14 KIK57669.1 - 1.1e-88 297.3 5.8 1.1e-88 297.3 5.8 2.3 2 1 0 2 2 2 1 XAP5, circadian clock regulator DUF2333 PF10095.9 KIK57669.1 - 3 6.8 5.7 4.3 6.3 5.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) WBS_methylT PF12589.8 KIK57670.1 - 8.4e-24 84.1 10.7 8.4e-24 84.1 10.7 1.5 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KIK57670.1 - 3.4e-09 37.2 0.0 6.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57670.1 - 1.7e-07 31.8 0.0 3.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK57670.1 - 7.9e-05 23.3 0.0 0.00023 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK57670.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57670.1 - 0.0023 17.8 0.0 0.0063 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KIK57670.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BCS1_N PF08740.11 KIK57671.1 - 1.2e-42 146.1 0.1 1.8e-42 145.5 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIK57671.1 - 5.3e-17 62.5 0.0 9.1e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK57671.1 - 0.0014 19.0 0.0 0.0055 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIK57671.1 - 0.0022 18.0 0.0 0.031 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KIK57671.1 - 0.005 16.0 0.0 3 6.9 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.6 KIK57671.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK57671.1 - 0.013 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KIK57671.1 - 0.014 15.0 0.0 0.059 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK57671.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIK57671.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIK57671.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KIK57671.1 - 0.062 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIK57671.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KIK57671.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KIK57672.1 - 2.9e-16 59.8 0.0 5.7e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DnaJ PF00226.31 KIK57672.1 - 2.6e-15 56.3 0.0 8.7e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 KIK57672.1 - 2.8e-08 34.1 0.0 1.7e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK57672.1 - 1e-06 28.9 0.1 2.2e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK57672.1 - 2.8e-05 24.2 0.0 0.009 16.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KIK57672.1 - 0.00021 21.6 0.0 0.13 12.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat DUF2336 PF10098.9 KIK57672.1 - 0.9 9.0 15.9 2.4 7.6 15.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) Asp-B-Hydro_N PF05279.11 KIK57672.1 - 1.1 9.3 15.9 1.7 8.6 15.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SRP-alpha_N PF04086.13 KIK57672.1 - 2.3 8.0 21.4 0.35 10.7 13.5 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Neur_chan_memb PF02932.16 KIK57672.1 - 4.6 7.2 5.2 2 8.4 1.6 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LUC7 PF03194.15 KIK57673.1 - 1.4e-70 237.8 4.3 1.8e-70 237.5 4.3 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Phage_Gp19 PF09355.10 KIK57674.1 - 1.9 8.9 4.2 14 6.1 0.5 2.6 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 UCH PF00443.29 KIK57675.1 - 6e-34 117.7 0.8 1.2e-33 116.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK57675.1 - 2.6e-20 73.3 0.3 2.1e-19 70.3 0.3 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIK57675.1 - 5.1e-09 35.8 0.2 1e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KIK57675.1 - 0.00083 19.9 0.2 1 10.0 0.0 3.3 3 0 0 3 3 3 2 DUSP domain Rad60-SLD PF11976.8 KIK57675.1 - 0.034 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Gaa1 PF04114.14 KIK57676.1 - 1e-110 371.2 6.9 1.3e-109 367.5 6.9 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Tom37 PF10568.9 KIK57677.1 - 9.6e-25 87.3 0.1 1.4e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KIK57677.1 - 5.3e-11 42.1 0.0 9.5e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK57677.1 - 5.5e-08 33.5 0.0 1.1e-07 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KIK57677.1 - 8.7e-06 25.7 0.1 2.3e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Sporozoite_P67 PF05642.11 KIK57678.1 - 0.041 12.0 0.8 0.059 11.4 0.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Exo_endo_phos PF03372.23 KIK57680.1 - 2.4e-13 50.2 0.0 4e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Caskin-Pro-rich PF16907.5 KIK57680.1 - 0.029 14.9 0.4 0.053 14.0 0.4 1.4 1 0 0 1 1 1 0 Proline rich region of Caskin proteins RLL PF10036.9 KIK57680.1 - 0.1 12.4 0.4 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein OTU PF02338.19 KIK57681.1 - 0.00048 20.6 0.0 0.00086 19.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 KIK57681.1 - 0.037 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIK57681.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FRG1 PF06229.12 KIK57682.1 - 3.6e-25 88.8 0.0 3.6e-25 88.8 0.0 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 KIK57682.1 - 0.0016 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Fascin domain BRF1 PF07741.13 KIK57682.1 - 9.2 6.7 10.6 23 5.4 7.3 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain Ras PF00071.22 KIK57684.1 - 5.1e-50 169.2 0.0 6.1e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK57684.1 - 5.1e-30 104.2 0.0 8e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK57684.1 - 7e-10 38.6 0.0 9.5e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK57684.1 - 0.00051 19.5 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK57684.1 - 0.0026 17.9 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIK57684.1 - 0.0059 15.8 1.2 1.1 8.3 0.2 2.5 2 1 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.22 KIK57684.1 - 0.017 15.5 0.1 0.15 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK57684.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KIK57684.1 - 0.029 13.8 0.2 0.049 13.1 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF5118 PF17162.4 KIK57684.1 - 0.037 13.8 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 KIK57684.1 - 0.049 13.4 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIK57684.1 - 0.068 13.1 0.1 9.3 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KIK57684.1 - 0.091 13.1 0.2 0.096 13.1 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIK57684.1 - 0.11 12.7 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 KIK57684.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain TsaE PF02367.17 KIK57684.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KIK57684.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Septin ATPase PF06745.13 KIK57684.1 - 0.19 11.0 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 KaiC MFS_1 PF07690.16 KIK57685.1 - 1.1e-48 166.0 39.1 3.7e-48 164.2 39.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK57685.1 - 8.6e-18 64.1 17.3 1.2e-17 63.6 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK57685.1 - 9.3e-15 54.4 12.0 9.3e-15 54.4 12.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 KIK57685.1 - 0.073 13.3 1.5 0.83 9.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) S1FA PF04689.13 KIK57685.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.8 3 0 0 3 3 3 0 DNA binding protein S1FA Ferric_reduct PF01794.19 KIK57686.1 - 3.8e-20 72.3 9.1 3.8e-20 72.3 9.1 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK57686.1 - 1.2e-12 47.8 0.0 3.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIK57686.1 - 3.2e-09 37.1 0.0 7.4e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Vac_ImportDeg PF09783.9 KIK57687.1 - 1.3e-54 184.4 0.1 1.2e-53 181.3 0.1 2.0 1 1 0 1 1 1 1 Vacuolar import and degradation protein zinc_ribbon_4 PF13717.6 KIK57687.1 - 0.22 11.5 1.5 0.58 10.1 1.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain FMO-like PF00743.19 KIK57688.1 - 2e-12 46.3 1.6 2.1e-10 39.6 1.6 3.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK57688.1 - 3.2e-11 43.3 0.0 9.1e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK57688.1 - 9.9e-11 41.4 0.0 3.8e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK57688.1 - 5.2e-09 35.8 0.7 1.6e-07 30.9 0.5 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK57688.1 - 1.1e-07 31.3 0.4 1.6e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIK57688.1 - 0.0001 22.0 0.0 0.00034 20.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK57688.1 - 0.00011 21.6 0.2 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KIK57688.1 - 0.0014 17.8 0.2 0.0024 17.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIK57688.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK57688.1 - 0.016 15.2 0.2 0.15 12.0 0.0 2.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.22 KIK57688.1 - 0.043 12.9 0.1 0.35 9.9 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Xylo_C PF12529.8 KIK57688.1 - 0.053 13.1 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Xylosyltransferase C terminal FAD_binding_3 PF01494.19 KIK57688.1 - 0.12 11.6 0.3 0.25 10.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KIK57688.1 - 0.2 11.0 0.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIK57688.1 - 3 8.5 5.5 0.32 11.6 0.2 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIK57689.1 - 7.3e-26 91.1 0.0 1e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57689.1 - 1.6e-12 47.3 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK57689.1 - 2.2e-07 30.0 0.0 3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK57689.1 - 0.0038 17.2 0.0 0.78 9.6 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family JmjC PF02373.22 KIK57690.1 - 1.5e-09 38.3 0.2 1.5e-09 38.3 0.2 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF5382 PF17354.2 KIK57690.1 - 0.11 11.3 0.2 0.18 10.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5382) ZapB PF06005.12 KIK57690.1 - 0.11 12.9 9.7 0.37 11.3 9.7 1.9 1 0 0 1 1 1 0 Cell division protein ZapB RecR PF02132.15 KIK57690.1 - 0.54 9.9 12.5 0.14 11.7 7.5 2.5 2 0 0 2 2 2 0 RecR protein zf-RING_5 PF14634.6 KIK57691.1 - 9.3e-08 31.9 5.3 1.6e-07 31.2 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C2HC5 PF06221.13 KIK57691.1 - 0.012 15.6 0.4 0.029 14.4 0.4 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF5094 PF17015.5 KIK57691.1 - 0.029 14.5 0.1 0.047 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TerY_C PF15616.6 KIK57691.1 - 0.25 11.5 3.4 1.1 9.4 1.8 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain THOC7 PF05615.13 KIK57691.1 - 0.35 11.2 4.0 0.69 10.2 4.0 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 ZapB PF06005.12 KIK57691.1 - 2.6 8.5 9.2 0.053 14.0 2.3 1.7 2 0 0 2 2 2 0 Cell division protein ZapB LEA_2 PF03168.13 KIK57692.1 - 1.1e-06 29.1 0.0 1.9e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KIK57692.1 - 0.0015 17.8 0.1 0.0023 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) GFA PF04828.14 KIK57693.1 - 2.4e-10 40.6 0.8 5.1e-10 39.6 0.8 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF726 PF05277.12 KIK57694.1 - 5.1e-89 298.6 1.9 8.4e-89 297.9 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_8 PF06259.12 KIK57694.1 - 0.0072 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase Cutinase PF01083.22 KIK57694.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 KIK57694.1 - 0.02 15.5 1.3 0.031 14.9 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family VirJ PF06057.11 KIK57694.1 - 0.058 13.3 0.1 2.2 8.1 0.0 3.1 3 2 0 4 4 4 0 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.20 KIK57694.1 - 0.11 12.1 0.0 0.72 9.4 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Sulf_transp PF04143.14 KIK57695.1 - 2.2e-07 30.8 25.8 2.8e-06 27.1 11.1 2.9 1 1 2 3 3 3 3 Sulphur transport ADH_zinc_N PF00107.26 KIK57696.1 - 2e-20 73.1 0.1 3.6e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK57696.1 - 6.5e-12 46.7 0.1 1.5e-11 45.4 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK57696.1 - 5.7e-07 29.4 0.0 1.2e-05 25.1 0.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KIK57696.1 - 0.064 13.4 0.2 0.22 11.7 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Pkinase PF00069.25 KIK57697.1 - 4.4e-33 114.8 0.0 1.6e-32 112.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57697.1 - 4.3e-12 45.9 0.0 1.7e-11 43.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KIK57697.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family P5CR_dimer PF14748.6 KIK57697.1 - 0.18 12.1 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation Pentapeptide_3 PF13576.6 KIK57697.1 - 1.2 9.3 5.5 0.42 10.8 0.6 2.4 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Torus PF16131.5 KIK57698.1 - 1.1e-06 29.3 0.1 2e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KIK57698.1 - 5.6e-06 26.2 2.1 2e-05 24.5 2.1 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KIK57698.1 - 0.00067 19.5 2.1 0.0023 17.8 2.1 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK57698.1 - 0.0016 18.2 1.8 0.0047 16.7 1.8 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KIK57698.1 - 0.0027 17.9 0.7 0.0068 16.6 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KIK57698.1 - 0.02 15.4 1.7 0.02 15.4 1.7 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NAD_binding_7 PF13241.6 KIK57699.1 - 8.2e-29 100.1 0.0 1.2e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIK57699.1 - 2e-19 69.0 0.1 3.2e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIK57699.1 - 2.6e-12 45.9 0.2 5.8e-12 44.8 0.2 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 KIK57699.1 - 0.0024 17.3 0.1 0.09 12.1 0.0 2.2 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.20 KIK57699.1 - 0.0026 17.8 0.0 0.0065 16.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KIK57699.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain RTC PF01137.21 KIK57700.1 - 8.6e-59 198.4 0.0 9.8e-59 198.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIK57700.1 - 1e-38 132.0 0.0 1.5e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain ThiF PF00899.21 KIK57701.1 - 3.4e-63 213.2 0.0 4.9e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KIK57701.1 - 2.9e-28 97.8 0.1 4.5e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KIK57701.1 - 0.0068 16.5 0.3 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIK57701.1 - 0.026 14.1 0.1 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KIK57701.1 - 0.047 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 KIK57701.1 - 0.1 13.2 0.1 0.27 11.9 0.1 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Ecm33 PF12454.8 KIK57701.1 - 0.15 12.2 2.8 0.33 11.1 2.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Sacchrp_dh_NADP PF03435.18 KIK57701.1 - 0.16 12.2 0.0 2.2 8.5 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KIK57701.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NPR2 PF06218.11 KIK57702.1 - 1.5e-94 317.3 4.2 6.1e-92 308.7 4.2 3.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 OGG_N PF07934.12 KIK57703.1 - 1.2e-31 109.3 0.0 1.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KIK57703.1 - 4.6e-15 56.0 0.0 8.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GATA PF00320.27 KIK57704.1 - 0.71 9.5 4.9 4.5 7.0 0.3 3.1 1 1 2 3 3 3 0 GATA zinc finger NMT_C PF02799.15 KIK57706.1 - 8.1e-80 267.3 0.0 1.2e-79 266.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KIK57706.1 - 2.9e-76 254.7 0.0 5.1e-76 253.9 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KIK57706.1 - 0.0023 18.0 0.1 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK57706.1 - 0.011 16.0 0.1 0.031 14.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family ParD PF09386.10 KIK57706.1 - 0.012 16.0 0.4 0.028 14.8 0.4 1.6 1 0 0 1 1 1 0 Antitoxin ParD HrcA_DNA-bdg PF03444.15 KIK57706.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Lipoprotein_2 PF00921.17 KIK57706.1 - 0.076 12.6 11.6 0.14 11.7 11.6 1.4 1 0 0 1 1 1 0 Borrelia lipoprotein TMEM214 PF10151.9 KIK57706.1 - 1.9 6.9 7.3 2.4 6.5 7.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Sigma70_ner PF04546.13 KIK57706.1 - 6.1 6.7 8.4 9.6 6.0 8.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region UFD1 PF03152.14 KIK57707.1 - 8.6e-68 227.2 0.0 1.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cpn60_TCP1 PF00118.24 KIK57708.1 - 1e-134 449.9 16.9 3.6e-134 448.1 16.9 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RhoGEF67_u2 PF16614.5 KIK57708.1 - 0.097 12.8 0.1 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 TMEM239 PF15841.5 KIK57710.1 - 0.12 12.2 0.2 0.18 11.7 0.0 1.4 2 0 0 2 2 2 0 Transmembrane protein 239 family Mito_carr PF00153.27 KIK57711.1 - 7.6e-46 154.0 1.9 3.1e-16 59.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.9 KIK57712.1 - 8e-21 74.3 0.0 9.2e-10 37.7 0.0 3.2 2 1 1 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.22 KIK57713.1 - 5.7e-23 81.5 2.8 9.8e-22 77.4 1.9 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 FAD_oxidored PF12831.7 KIK57714.1 - 0.015 14.6 0.0 0.046 13.1 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK57714.1 - 0.044 12.6 0.1 0.94 8.2 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK57714.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 KIK57716.1 - 9.3e-15 54.8 0.1 1.6e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIK57716.1 - 8.8e-06 25.5 0.0 2.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 LisH DUF4217 PF13959.6 KIK57716.1 - 0.13 12.5 0.2 30 4.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Methyltransf_2 PF00891.18 KIK57717.1 - 1e-20 74.0 0.0 4.1e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 KIK57717.1 - 0.00053 19.9 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain HARE-HTH PF05066.13 KIK57717.1 - 0.0071 16.7 0.1 0.019 15.4 0.1 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Dimerisation2 PF16864.5 KIK57717.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain RPA_C PF08784.11 KIK57717.1 - 0.051 14.2 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal PepSY_2 PF13670.6 KIK57717.1 - 0.065 13.2 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Methyltransf_16 PF10294.9 KIK57717.1 - 0.069 12.9 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase MTS PF05175.14 KIK57717.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KIK57717.1 - 0.11 13.3 0.0 0.41 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain SASRP1 PF15160.6 KIK57719.1 - 4.8 6.8 5.5 6.2 6.4 5.5 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 SNF2_N PF00176.23 KIK57721.1 - 4.1e-56 190.2 0.0 6.6e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KIK57721.1 - 2.9e-43 148.2 9.5 5.1e-43 147.3 9.5 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KIK57721.1 - 1.5e-16 60.7 0.0 3.9e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK57721.1 - 1.8e-06 28.1 0.0 5.9e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK57721.1 - 4.1e-05 22.9 0.0 9.3e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KIK57721.1 - 0.00015 21.0 0.0 0.0012 18.1 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DAO PF01266.24 KIK57722.1 - 1.6e-33 116.8 0.1 1.9e-33 116.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK57722.1 - 0.0024 17.2 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK57722.1 - 0.0037 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK57722.1 - 0.012 14.9 0.0 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK57722.1 - 0.057 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KIK57722.1 - 0.075 13.0 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KIK57722.1 - 0.085 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GYF PF02213.16 KIK57724.1 - 1e-06 28.3 2.3 2.5e-06 27.0 2.3 1.7 1 0 0 1 1 1 1 GYF domain PQ-loop PF04193.14 KIK57725.1 - 1.5e-38 130.3 9.3 1.5e-19 69.5 1.0 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KIK57725.1 - 0.054 13.5 2.5 0.096 12.7 0.5 2.3 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ins_P5_2-kin PF06090.12 KIK57726.1 - 1.5e-65 221.8 0.0 1.7e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Chromo PF00385.24 KIK57728.1 - 2.3e-10 40.2 2.6 4.1e-10 39.4 2.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2367 PF10164.9 KIK57729.1 - 3.8e-06 27.3 11.9 8.1e-06 26.3 11.9 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.9 KIK57729.1 - 0.03 14.6 4.0 0.038 14.3 4.0 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Tudor_2 PF18104.1 KIK57730.1 - 0.00035 20.2 0.0 0.00086 18.9 0.0 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 KIK57730.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 KIK57730.1 - 0.0042 17.3 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT_3 PF18428.1 KIK57730.1 - 0.0043 17.1 0.1 0.014 15.4 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PH_14 PF17787.1 KIK57730.1 - 0.0062 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 PH domain BRCT PF00533.26 KIK57730.1 - 0.0094 16.3 0.1 0.082 13.3 0.0 2.6 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain TUDOR_5 PF18359.1 KIK57730.1 - 0.15 11.8 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 PIRT PF15099.6 KIK57731.1 - 0.094 12.3 0.3 0.26 10.9 0.3 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Nuc_sug_transp PF04142.15 KIK57732.1 - 1e-98 330.4 18.1 1.3e-98 330.0 18.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KIK57732.1 - 4.8e-06 26.0 12.6 8.2e-06 25.2 12.6 1.3 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 KIK57732.1 - 5.8e-05 22.2 4.3 5.8e-05 22.2 4.3 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KIK57732.1 - 0.00093 19.4 4.6 0.00093 19.4 4.6 2.9 2 2 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KIK57732.1 - 0.013 14.8 18.5 0.18 11.0 18.5 2.2 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF202 PF02656.15 KIK57732.1 - 0.014 15.8 1.0 0.014 15.8 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PNTB PF02233.16 KIK57733.1 - 5.1e-176 586.1 24.5 5.1e-176 586.1 24.5 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KIK57733.1 - 7.6e-70 234.5 0.2 2.2e-69 233.0 0.2 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KIK57733.1 - 2.2e-44 151.1 0.0 4.8e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KIK57733.1 - 3.1e-32 110.9 2.6 3.1e-32 110.9 2.6 4.5 3 1 1 5 5 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KIK57733.1 - 5.5e-05 22.6 0.3 0.035 13.5 0.1 3.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KIK57733.1 - 0.0075 15.5 0.2 0.017 14.4 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KIK57733.1 - 0.014 15.4 0.2 0.1 12.6 0.2 2.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GIDA PF01134.22 KIK57733.1 - 0.02 14.0 0.8 0.032 13.3 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK57733.1 - 0.033 13.3 0.4 0.066 12.3 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain TPP_enzyme_M PF00205.22 KIK57733.1 - 0.053 13.3 0.2 0.46 10.2 0.1 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fumerase PF05681.14 KIK57733.1 - 0.12 11.8 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NAD_binding_8 PF13450.6 KIK57733.1 - 0.68 10.2 4.5 0.24 11.7 0.2 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DHDPS PF00701.22 KIK57734.1 - 1.7e-28 99.2 0.0 4.7e-28 97.7 0.0 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family TruB_N PF01509.18 KIK57735.1 - 2e-44 151.6 0.0 1.2e-43 149.1 0.0 1.9 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KIK57735.1 - 8.9e-05 22.6 0.0 0.00043 20.4 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Med16 PF11635.8 KIK57736.1 - 5.5e-05 21.3 2.6 0.00032 18.8 2.6 2.2 1 1 0 1 1 1 1 Mediator complex subunit 16 PIG-P PF08510.12 KIK57736.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 PIG-P PAC3 PF10178.9 KIK57737.1 - 0.0061 16.7 3.8 0.02 15.0 3.8 1.8 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 NCE101 PF11654.8 KIK57738.1 - 9.4e-19 66.9 0.1 1.3e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 NatB_MDM20 PF09797.9 KIK57739.1 - 3.1e-72 243.7 6.7 8.5e-72 242.2 3.7 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 KIK57739.1 - 7.2e-10 38.9 0.0 0.3 12.0 0.0 5.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK57739.1 - 1.3e-07 32.1 3.0 0.00014 22.3 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK57739.1 - 1e-05 26.1 0.1 0.2 12.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KIK57739.1 - 0.00074 20.0 4.1 0.015 15.8 0.4 4.1 4 1 1 5 5 4 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KIK57739.1 - 0.0012 19.0 8.3 0.051 13.8 0.2 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIK57739.1 - 0.0027 17.5 0.0 6.8 6.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK57739.1 - 0.0063 16.6 0.2 1.5 9.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KIK57739.1 - 0.023 14.1 0.3 0.049 13.0 0.3 1.5 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_7 PF13176.6 KIK57739.1 - 0.027 14.5 0.3 37 4.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK57739.1 - 0.17 12.0 1.0 7.6 6.7 0.3 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KIK57739.1 - 0.53 10.6 4.2 47 4.4 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat RPA_C PF08784.11 KIK57740.1 - 0.0018 18.9 0.0 0.0035 18.0 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal ORC6 PF05460.13 KIK57740.1 - 0.033 13.5 1.1 0.043 13.1 1.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) tRNA_anti-codon PF01336.25 KIK57740.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain ATG_C PF09333.11 KIK57741.1 - 5.1e-37 126.1 0.2 1.4e-36 124.7 0.2 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 KIK57741.1 - 7.2e-12 45.3 0.0 4.2e-11 42.8 0.0 2.3 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 KIK57741.1 - 3.1e-10 40.2 0.0 1.1e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KIK57741.1 - 0.00082 19.2 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Ribosomal_L24e PF01246.20 KIK57742.1 - 2e-32 111.2 6.2 2e-32 111.2 6.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Cytochrom_C550 PF14495.6 KIK57742.1 - 0.091 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-550 domain zf-FCS PF06467.14 KIK57742.1 - 0.11 12.5 4.1 0.19 11.7 4.1 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HAGH_C PF16123.5 KIK57742.1 - 0.18 12.4 1.9 0.26 11.9 0.3 2.0 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Inv-AAD PF18785.1 KIK57743.1 - 6.2e-28 97.2 0.0 8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KIK57743.1 - 1.3e-15 57.0 0.2 1.9e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK57743.1 - 0.0082 15.9 1.0 0.049 13.4 1.0 2.2 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KIK57743.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 APOBEC-like N-terminal domain SH2_2 PF14633.6 KIK57744.1 - 1.6e-72 243.4 0.4 1.6e-72 243.4 0.4 2.7 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 KIK57744.1 - 7.3e-31 106.6 0.0 1.4e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KIK57744.1 - 1.6e-28 99.4 0.0 5.4e-28 97.7 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KIK57744.1 - 7.8e-25 87.5 0.1 2.5e-24 85.9 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KIK57744.1 - 8.9e-20 71.1 35.1 8.9e-20 71.1 35.1 5.6 6 2 2 8 8 8 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KIK57744.1 - 6.9e-07 30.1 1.0 8.1e-06 26.7 1.0 2.8 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KIK57744.1 - 9.5e-06 25.6 0.0 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.7 KIK57744.1 - 0.0029 17.8 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SRP54 PF00448.22 KIK57746.1 - 1.1e-72 243.8 1.1 2.1e-72 242.9 1.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KIK57746.1 - 9.1e-29 100.0 0.4 9.1e-29 100.0 0.4 3.9 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 KIK57746.1 - 4.3e-19 68.5 4.1 1e-18 67.3 4.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KIK57746.1 - 0.00037 20.7 0.1 0.00075 19.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIK57746.1 - 0.00064 19.8 0.0 0.0025 17.8 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KIK57746.1 - 0.0022 17.0 0.5 0.0022 17.0 0.5 2.6 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KIK57746.1 - 0.0059 17.0 0.1 0.0059 17.0 0.1 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK57746.1 - 0.034 13.9 0.1 0.034 13.9 0.1 2.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KIK57746.1 - 0.058 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin HTH_ParB PF17762.1 KIK57746.1 - 0.16 11.8 2.0 3 7.7 0.3 2.7 2 0 0 2 2 2 0 HTH domain found in ParB protein 6PF2K PF01591.18 KIK57746.1 - 0.17 11.2 0.9 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KIK57746.1 - 0.27 11.0 1.3 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SurA_N PF09312.11 KIK57746.1 - 9.1 6.4 7.0 1.2 9.2 0.1 2.9 3 0 0 3 3 3 0 SurA N-terminal domain WD40 PF00400.32 KIK57747.1 - 4.9e-14 52.5 14.6 0.017 16.0 0.2 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57747.1 - 0.00013 22.2 0.1 1.2 9.4 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 KIK57747.1 - 0.048 12.3 7.7 0.1 11.1 7.7 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Methyltransf_23 PF13489.6 KIK57748.1 - 2e-13 50.5 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57748.1 - 4.5e-11 43.3 0.0 0.00018 22.2 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KIK57748.1 - 1.3e-10 41.3 0.0 0.00017 21.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57748.1 - 3.2e-10 40.5 0.0 2.1e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK57748.1 - 1.5e-05 25.6 0.0 0.079 13.7 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KIK57748.1 - 0.00041 19.9 0.0 0.0095 15.4 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KIK57748.1 - 0.00096 18.7 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIK57748.1 - 0.0018 17.7 0.0 0.095 12.0 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KIK57748.1 - 0.0024 17.2 0.0 0.17 11.2 0.0 2.5 2 1 0 2 2 2 1 O-methyltransferase domain Methyltransf_29 PF03141.16 KIK57748.1 - 0.0026 16.4 0.0 0.0074 14.9 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KIK57748.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KIK57748.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_8 PF05148.15 KIK57748.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Thymidylate_kin PF02223.17 KIK57750.1 - 4.2e-23 82.0 0.0 1.7e-20 73.5 0.0 2.1 1 1 0 1 1 1 1 Thymidylate kinase DUF3921 PF13060.6 KIK57750.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) ADH_zinc_N PF00107.26 KIK57751.1 - 4.4e-11 42.9 0.0 7.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK57751.1 - 3.5e-10 39.7 0.0 1.3e-09 37.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIK57751.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase MAF_flag10 PF01973.18 KIK57751.1 - 0.031 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 AlaDh_PNT_C PF01262.21 KIK57751.1 - 0.11 11.7 0.5 0.26 10.5 0.0 1.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 KIK57752.1 - 6.9e-10 39.0 0.1 1.4e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK57752.1 - 1.4e-07 31.4 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MAF_flag10 PF01973.18 KIK57752.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 PXA PF02194.15 KIK57753.1 - 3.3e-44 151.1 0.1 6.6e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 PXA domain DUF1722 PF08349.11 KIK57754.1 - 0.038 14.3 1.3 0.94 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) BST2 PF16716.5 KIK57754.1 - 0.27 11.8 1.8 0.63 10.7 1.8 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF739 PF05339.11 KIK57757.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF739) adh_short PF00106.25 KIK57758.1 - 2.4e-39 134.8 0.0 3.2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57758.1 - 6.9e-27 94.5 0.0 9.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIK57758.1 - 0.00047 20.1 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KIK57758.1 - 0.035 13.5 0.0 0.063 12.6 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KIK57759.1 - 2e-37 128.6 0.0 2.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57759.1 - 1.2e-24 87.2 0.0 1.5e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIK57759.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KIK57760.1 - 9.3e-38 129.6 0.0 1.4e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57760.1 - 1.3e-24 87.1 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIK57760.1 - 0.0041 17.0 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KIK57760.1 - 0.0049 16.3 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TPP_enzyme_M PF00205.22 KIK57760.1 - 0.012 15.4 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.22 KIK57761.1 - 2.5e-84 277.1 2.1 8.9e-22 76.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KIK57761.1 - 1.7e-25 89.0 1.4 6e-25 87.2 1.5 1.9 2 0 0 2 2 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KIK57761.1 - 4.3e-08 32.8 0.0 0.066 12.8 0.0 4.1 1 1 3 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK57761.1 - 0.00033 20.7 0.2 5.7 7.1 0.0 4.5 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK57761.1 - 0.0013 18.7 0.7 3.3 7.8 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK57761.1 - 0.0018 18.3 6.4 1.5 8.9 1.5 3.8 4 0 0 4 4 4 2 RNA binding motif YflT PF11181.8 KIK57761.1 - 0.0044 17.5 1.4 0.66 10.5 0.6 2.6 2 0 0 2 2 2 1 Heat induced stress protein YflT DUF4407 PF14362.6 KIK57761.1 - 0.0076 15.6 0.9 0.013 14.9 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) OB_RNB PF08206.11 KIK57761.1 - 0.0095 15.6 2.4 13 5.5 0.1 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain PNPase PF03726.14 KIK57761.1 - 0.065 13.7 2.1 0.25 11.9 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Erf4 PF10256.9 KIK57761.1 - 0.24 11.5 0.3 3.8 7.6 0.1 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Nefa_Nip30_N PF10187.9 KIK57761.1 - 0.44 10.9 6.3 0.34 11.3 0.4 2.6 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SKG6 PF08693.10 KIK57762.1 - 0.00064 19.1 0.8 0.0013 18.1 0.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 KIK57762.1 - 0.043 12.6 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KIK57762.1 - 0.049 13.5 0.2 0.092 12.7 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KIK57762.1 - 0.099 13.5 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KIK57762.1 - 0.17 11.7 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5305 PF17231.2 KIK57762.1 - 0.24 10.8 0.0 1.3 8.4 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Gly-zipper_Omp PF13488.6 KIK57762.1 - 0.28 11.2 10.7 0.8 9.8 10.7 1.7 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KIK57762.1 - 0.71 9.7 8.7 1.8 8.4 8.7 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Beta-APP PF03494.13 KIK57762.1 - 0.78 9.6 6.3 1.4 8.8 6.3 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SCAMP PF04144.13 KIK57763.1 - 1e-54 185.4 12.2 1.3e-54 185.1 12.2 1.0 1 0 0 1 1 1 1 SCAMP family Cys_rich_CPXG PF14255.6 KIK57764.1 - 0.021 14.7 2.8 0.2 11.6 0.1 2.8 2 1 0 2 2 2 0 Cysteine-rich CPXCG Apt1 PF10351.9 KIK57764.1 - 0.066 12.1 10.6 0.078 11.8 10.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KIK57764.1 - 0.24 10.5 17.2 0.3 10.2 17.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 KIK57764.1 - 0.58 8.9 5.2 0.66 8.7 5.2 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 KIK57764.1 - 1.4 8.8 19.8 1.8 8.4 19.8 1.1 1 0 0 1 1 1 0 SPX domain CDC45 PF02724.14 KIK57764.1 - 3.6 5.8 7.6 4.6 5.4 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 KIK57764.1 - 6.9 5.1 9.0 8.6 4.8 9.0 1.0 1 0 0 1 1 1 0 Utp14 protein Toxin_14 PF07829.11 KIK57764.1 - 9.6 6.2 10.0 10 6.1 4.8 2.9 2 1 0 2 2 2 0 Alpha-A conotoxin PIVA-like protein Epimerase PF01370.21 KIK57765.1 - 6.6e-07 29.0 0.2 1.2e-05 24.9 0.0 2.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK57765.1 - 0.0001 22.2 0.0 0.00029 20.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK57765.1 - 0.0057 15.7 0.0 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIK57765.1 - 0.0071 15.8 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KIK57765.1 - 0.0092 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIK57765.1 - 0.037 13.1 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KIK57765.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 KIK57765.1 - 0.2 10.8 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein ADK PF00406.22 KIK57766.1 - 2.2e-43 148.0 0.0 3.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIK57766.1 - 2.6e-20 73.2 0.0 7.3e-20 71.8 0.0 1.8 3 0 0 3 3 3 1 AAA domain ADK_lid PF05191.14 KIK57766.1 - 4e-14 52.3 0.0 6.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIK57766.1 - 1.7e-07 31.8 0.0 3.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK57766.1 - 0.00082 19.5 0.0 0.0022 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIK57766.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 KIK57766.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA PF00004.29 KIK57766.1 - 0.19 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Methyltransf_PK PF05891.12 KIK57767.1 - 1.9e-51 174.6 0.0 1.2e-28 100.1 0.0 2.4 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KIK57767.1 - 2.2e-08 34.7 0.0 0.012 16.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIK57767.1 - 1.8e-05 25.4 0.0 0.00041 21.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57767.1 - 2.5e-05 24.8 0.0 0.29 11.8 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Swi3 PF07962.12 KIK57768.1 - 7.9e-30 102.7 0.3 1.3e-29 102.0 0.3 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DUF2737 PF10930.8 KIK57768.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) DEAD PF00270.29 KIK57769.1 - 2.3e-52 177.3 0.0 7e-51 172.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK57769.1 - 6.5e-33 113.4 0.0 9.7e-32 109.6 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK57769.1 - 5e-08 33.1 0.0 2.2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KIK57769.1 - 0.0011 17.9 0.0 0.0059 15.4 0.0 2.1 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 KIK57769.1 - 0.021 15.2 0.1 6.8 7.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF2443 PF10398.9 KIK57769.1 - 0.056 13.5 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA PF00004.29 KIK57769.1 - 0.096 13.1 0.0 7.7 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GRP PF07172.11 KIK57769.1 - 0.42 11.3 24.7 1.2 9.9 24.7 1.8 1 0 0 1 1 1 0 Glycine rich protein family DnaJ PF00226.31 KIK57770.1 - 2.3e-10 40.4 0.1 5e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KIK57771.1 - 0.0009 20.0 8.2 0.014 16.2 1.2 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK57771.1 - 0.01 16.1 0.2 1.1 9.5 0.0 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain POT1PC PF16686.5 KIK57771.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Sybindin PF04099.12 KIK57772.1 - 1e-39 135.7 0.0 1.2e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KIK57772.1 - 1.8e-07 31.3 0.0 1.8e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SAP PF02037.27 KIK57775.1 - 3.9e-12 45.6 0.0 6.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain DUF2315 PF10231.9 KIK57776.1 - 9.4e-26 90.3 3.1 2.3e-25 89.1 3.1 1.6 1 1 0 1 1 1 1 Apoptogenic protein 1 Nucleoporin_C PF03177.14 KIK57777.1 - 5.6e-83 279.7 2.8 5.2e-81 273.2 1.5 2.4 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KIK57777.1 - 6e-13 48.3 0.0 8.2e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DNA_RNApol_7kD PF03604.13 KIK57778.1 - 6e-18 64.2 7.2 7.4e-18 63.9 7.2 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 KIK57778.1 - 0.0017 18.0 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KIK57778.1 - 0.0021 18.0 0.8 0.0029 17.6 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KIK57778.1 - 0.0079 16.2 0.3 0.0086 16.1 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NinF PF05810.12 KIK57778.1 - 0.0094 15.8 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 NinF protein zf-ISL3 PF14690.6 KIK57778.1 - 0.011 16.4 2.3 0.039 14.6 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.6 KIK57778.1 - 0.012 16.1 2.9 0.2 12.2 0.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KIK57778.1 - 0.017 15.2 3.8 0.042 14.0 3.7 1.8 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KIK57778.1 - 0.026 14.2 2.1 0.25 11.1 2.1 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc-ribbon_6 PF10005.9 KIK57778.1 - 0.026 15.2 0.3 0.046 14.4 0.3 1.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.6 KIK57778.1 - 0.035 14.0 6.0 0.5 10.3 0.2 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zf-C3HC PF07967.13 KIK57778.1 - 0.037 14.1 0.0 0.037 14.1 0.0 1.0 1 0 0 1 1 1 0 C3HC zinc finger-like MCM_OB PF17207.3 KIK57778.1 - 0.039 13.8 0.6 0.042 13.7 0.6 1.1 1 0 0 1 1 1 0 MCM OB domain TF_Zn_Ribbon PF08271.12 KIK57778.1 - 0.049 13.2 2.4 0.94 9.1 0.1 2.1 1 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 KIK57778.1 - 0.073 13.1 1.5 0.34 11.0 1.6 1.8 1 1 1 2 2 2 0 Zinc-ribbon zf-NADH-PPase PF09297.11 KIK57778.1 - 0.09 12.5 3.6 0.27 10.9 3.6 1.7 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KIK57778.1 - 0.094 12.7 2.2 0.12 12.3 1.7 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 KIK57778.1 - 0.1 12.2 2.2 4.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 KIK57778.1 - 0.17 11.4 2.6 1.3 8.5 2.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KIK57778.1 - 0.25 11.4 3.2 12 6.0 1.5 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rubredoxin_2 PF18073.1 KIK57778.1 - 0.27 11.0 3.9 4.9 7.0 0.5 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Histone PF00125.24 KIK57779.1 - 8.1e-23 81.2 3.7 9.8e-23 81.0 3.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK57779.1 - 6.5e-05 23.1 1.3 8.1e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIK57779.1 - 0.00028 21.3 0.0 0.00052 20.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIK57779.1 - 0.019 15.0 0.3 0.023 14.7 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein DAGK_cat PF00781.24 KIK57780.1 - 2.6e-24 85.2 0.0 5.7e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 KIK57780.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Alpha-amylase PF00128.24 KIK57781.1 - 8.6e-18 65.0 2.3 2.7e-17 63.3 0.8 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KIK57781.1 - 2e-15 57.2 0.0 3.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIK57781.1 - 1.7e-07 30.9 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ferric_reduct PF01794.19 KIK57782.1 - 6.2e-18 65.1 12.7 6.2e-18 65.1 12.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK57782.1 - 2.3e-13 50.5 0.0 6e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK57782.1 - 1.5e-10 41.1 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain HMA PF00403.26 KIK57783.1 - 3.5e-07 30.6 1.2 5.7e-07 29.9 1.2 1.4 1 1 0 1 1 1 1 Heavy-metal-associated domain AA_permease_2 PF13520.6 KIK57784.1 - 1.7e-68 231.4 40.7 2.1e-68 231.1 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK57784.1 - 5.1e-29 101.2 31.4 7.6e-29 100.6 31.4 1.2 1 0 0 1 1 1 1 Amino acid permease LYRIC PF15686.5 KIK57784.1 - 0.2 11.2 0.5 0.31 10.6 0.5 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family TRM PF02005.16 KIK57785.1 - 7.4e-121 403.9 0.0 1e-120 403.4 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KIK57785.1 - 0.011 15.5 0.1 0.061 13.1 0.1 2.0 1 1 0 1 1 1 0 Met-10+ like-protein OB_Dis3 PF17849.1 KIK57785.1 - 0.09 12.8 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) Pkinase PF00069.25 KIK57786.1 - 3.8e-68 229.7 0.0 5.4e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57786.1 - 4.5e-49 167.1 0.0 8.2e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 KIK57786.1 - 2e-14 53.7 0.0 4.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KIK57786.1 - 1.1e-13 51.1 0.0 2.3e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 KIK57786.1 - 3.6e-12 46.5 0.0 8.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 KIK57786.1 - 1.8e-07 30.8 0.1 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIK57786.1 - 0.0012 17.7 0.0 0.0012 17.7 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase SAM_4 PF18017.1 KIK57786.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Kdo PF06293.14 KIK57786.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4746 PF15928.5 KIK57786.1 - 5.1 6.4 8.8 9 5.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) N36 PF11438.8 KIK57787.1 - 0.17 11.7 0.0 28 4.6 0.0 2.6 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) Histone PF00125.24 KIK57788.1 - 5.7e-23 81.7 3.7 6.9e-23 81.4 3.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK57788.1 - 7.8e-05 22.9 1.6 8.1e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIK57788.1 - 0.00028 21.3 0.0 0.00052 20.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIK57788.1 - 0.015 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein PRCC PF10253.9 KIK57789.1 - 5.2e-28 99.3 1.3 5.2e-28 99.3 1.3 3.0 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.16 KIK57790.1 - 3e-32 111.9 28.0 3e-32 111.9 28.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2985 PF11204.8 KIK57790.1 - 0.019 15.1 2.7 0.95 9.7 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) DENN PF02141.21 KIK57790.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 DENN (AEX-3) domain SpoVAB PF13782.6 KIK57790.1 - 0.46 10.8 7.7 0.52 10.6 0.7 2.5 2 0 0 2 2 2 0 Stage V sporulation protein AB S10_plectin PF03501.15 KIK57792.1 - 1.2e-45 153.4 0.1 1.5e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 KIK57792.1 - 0.0095 15.8 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LAB_N PF07578.11 KIK57793.1 - 0.21 11.7 2.7 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DPM2 PF07297.12 KIK57794.1 - 5.6e-29 100.3 0.3 6.6e-29 100.0 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KIK57794.1 - 4.5e-06 26.6 0.3 5.1e-06 26.4 0.3 1.1 1 0 0 1 1 1 1 PIG-P LapA_dom PF06305.11 KIK57794.1 - 0.012 15.4 0.1 0.012 15.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain UNC-79 PF14776.6 KIK57795.1 - 0.00058 18.7 0.0 0.0017 17.2 0.0 1.7 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 C1_1 PF00130.22 KIK57795.1 - 0.025 14.5 21.9 0.058 13.3 10.3 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Xpo1 PF08389.12 KIK57795.1 - 0.043 13.9 0.1 0.25 11.4 0.1 2.3 1 0 0 1 1 1 0 Exportin 1-like protein DUF4211 PF13926.6 KIK57796.1 - 1.4e-32 112.7 0.0 6.5e-32 110.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) TFIID-18kDa PF02269.16 KIK57797.1 - 5.7e-21 74.4 0.0 8.3e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit RRM_1 PF00076.22 KIK57798.1 - 1.4e-15 56.9 0.1 4.3e-15 55.3 0.1 1.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK57798.1 - 2.6e-07 30.6 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 KIK57798.1 - 9.3e-05 22.3 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KIK57798.1 - 0.0033 17.4 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KIK57799.1 - 3.8e-14 52.7 0.0 4.3e-11 42.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57799.1 - 1.6e-08 34.2 0.0 2.7e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Vps55 PF04133.14 KIK57800.1 - 3.5e-42 143.1 6.2 3.9e-42 142.9 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRAPPC9-Trs120 PF08626.11 KIK57801.1 - 1.5e-197 658.6 0.0 6.6e-163 543.8 0.0 2.0 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF2040 PF09745.9 KIK57802.1 - 5.7e-39 132.9 20.6 5.7e-39 132.9 20.6 3.2 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Kinesin PF00225.23 KIK57803.1 - 1.3e-104 349.8 0.0 2.8e-104 348.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK57803.1 - 1.2e-21 77.2 0.0 3.3e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KIK57803.1 - 3.3e-05 24.3 0.0 3.3e-05 24.3 0.0 4.4 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KIK57803.1 - 0.04 14.0 13.1 1.8 8.6 0.2 4.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TetR_C_13 PF16925.5 KIK57803.1 - 0.31 11.0 1.6 2.5 8.0 0.3 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2852 PF11014.8 KIK57803.1 - 4 7.6 7.1 9.1 6.5 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) Elf1 PF05129.13 KIK57804.1 - 2.4e-29 101.2 0.9 3e-29 100.9 0.9 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KIK57804.1 - 0.0071 16.8 0.5 0.011 16.3 0.5 1.3 1 0 0 1 1 1 1 CHY zinc finger Nup96 PF12110.8 KIK57804.1 - 0.057 12.5 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Kinesin PF00225.23 KIK57805.1 - 5.3e-112 374.0 0.2 1.8e-111 372.3 0.2 2.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK57805.1 - 1.1e-27 96.8 0.0 3.8e-27 95.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 KIK57805.1 - 1.2e-05 25.2 2.8 1.2e-05 25.2 2.8 4.0 3 1 0 3 3 3 1 Protein of unknown function (DUF465) TMF_TATA_bd PF12325.8 KIK57805.1 - 0.01 16.1 7.7 0.01 16.1 7.7 5.1 2 2 3 5 5 5 1 TATA element modulatory factor 1 TATA binding TFA2_Winged_2 PF18121.1 KIK57805.1 - 0.82 9.4 3.8 3.7 7.3 1.1 3.6 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 Rop PF01815.16 KIK57805.1 - 0.88 9.5 6.8 0.29 11.0 2.8 2.4 2 1 0 2 2 2 0 Rop protein PUF PF00806.19 KIK57806.1 - 9.7e-58 188.7 0.5 6.6e-09 35.0 0.1 8.5 8 1 0 8 8 8 8 Pumilio-family RNA binding repeat Methyltransf_25 PF13649.6 KIK57807.1 - 0.00028 21.5 0.0 0.017 15.8 0.0 2.3 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KIK57808.1 - 1.9e-07 31.7 0.0 0.00013 22.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KIK57808.1 - 0.037 14.7 0.0 0.62 10.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF1905 PF08922.11 KIK57808.1 - 0.12 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Sec16_C PF12931.7 KIK57809.1 - 6.5e-104 347.8 0.0 9.3e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KIK57809.1 - 1.8e-29 102.7 0.1 6.7e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region OST3_OST6 PF04756.13 KIK57810.1 - 6e-94 314.7 0.0 6.8e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KIK57810.1 - 0.0025 17.8 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF2627 PF11118.8 KIK57810.1 - 0.37 11.4 4.8 3.3 8.4 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) DUF3792 PF12670.7 KIK57810.1 - 4.7 7.4 9.7 1.1 9.4 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) PI3_PI4_kinase PF00454.27 KIK57812.1 - 2e-33 116.3 0.0 3e-32 112.4 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KIK57812.1 - 0.03 14.3 0.4 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 KIK57812.1 - 0.076 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KIK57812.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Glyco_transf_15 PF01793.16 KIK57813.1 - 7.9e-123 409.8 5.5 9.6e-123 409.6 5.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 KIK57814.1 - 6.8e-121 403.5 7.6 8.3e-121 403.2 7.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 KIK57815.1 - 1.8e-81 273.6 2.6 2.1e-81 273.3 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin PapD-like PF14874.6 KIK57815.1 - 0.18 12.0 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Flagellar-associated PapD-like ICMT PF04140.14 KIK57816.1 - 2.7e-11 43.7 0.1 2.7e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK57816.1 - 6.3e-10 39.4 2.8 2.8e-09 37.3 0.2 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK57816.1 - 0.00049 19.0 0.3 0.00085 18.2 0.3 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ABC_tran PF00005.27 KIK57817.1 - 8.9e-22 78.1 0.0 1.5e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK57817.1 - 9.3e-08 32.2 0.2 0.00097 19.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK57817.1 - 0.001 18.6 0.1 0.063 12.7 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KIK57817.1 - 0.001 19.0 0.9 0.0018 18.3 0.1 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK57817.1 - 0.0038 17.6 0.1 0.0042 17.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KIK57817.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK57817.1 - 0.009 16.3 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK57817.1 - 0.023 14.6 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 KIK57817.1 - 0.024 14.8 0.0 0.4 10.9 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KIK57817.1 - 0.024 15.1 0.1 0.025 15.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK57817.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KIK57817.1 - 0.03 14.3 0.2 0.054 13.4 0.1 1.4 2 0 0 2 2 1 0 Rad17 P-loop domain TsaE PF02367.17 KIK57817.1 - 0.033 14.2 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KIK57817.1 - 0.035 13.8 0.1 0.073 12.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIK57817.1 - 0.043 13.5 0.5 0.081 12.6 0.2 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 KIK57817.1 - 0.08 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KIK57817.1 - 0.081 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIK57817.1 - 0.1 12.6 0.1 0.33 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIK57817.1 - 0.15 12.2 0.4 0.41 10.8 0.2 1.7 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KIK57817.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein CbiA PF01656.23 KIK57817.1 - 0.18 11.8 0.6 0.4 10.8 0.3 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KIK57817.1 - 0.2 12.1 0.8 0.29 11.5 0.1 1.6 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 KIK57817.1 - 0.22 12.0 0.3 1.7 9.1 0.2 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK57817.1 - 0.24 11.9 0.3 0.47 11.0 0.1 1.5 2 0 0 2 2 1 0 AAA domain Atg14 PF10186.9 KIK57818.1 - 0.0072 15.4 8.0 0.016 14.3 0.4 2.6 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Trans_reg_C PF00486.28 KIK57818.1 - 0.018 15.1 0.4 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF3130 PF11328.8 KIK57818.1 - 0.072 13.3 0.5 23 5.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 DUF4407 PF14362.6 KIK57818.1 - 0.12 11.7 16.2 4.2 6.6 13.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 KIK57818.1 - 0.15 12.1 18.1 0.42 10.6 6.5 2.7 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Bap31_Bap29_C PF18035.1 KIK57818.1 - 0.39 10.8 0.0 0.39 10.8 0.0 4.5 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Seryl_tRNA_N PF02403.22 KIK57818.1 - 0.59 10.4 20.9 0.086 13.1 5.9 4.0 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Sec34 PF04136.15 KIK57818.1 - 2.3 8.1 11.0 0.67 9.8 0.9 3.8 3 1 0 3 3 3 0 Sec34-like family DUF3450 PF11932.8 KIK57818.1 - 3.3 6.9 20.1 0.016 14.5 2.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) FemAB PF02388.16 KIK57818.1 - 4.9 5.9 9.0 9.7 4.9 2.4 2.4 2 0 0 2 2 2 0 FemAB family FUSC PF04632.12 KIK57818.1 - 7.4 5.0 12.2 1.2 7.6 1.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF745 PF05335.13 KIK57818.1 - 7.6 6.2 13.2 0.042 13.6 2.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF2418 PF10332.9 KIK57819.1 - 8.1e-29 100.0 0.9 1.5e-28 99.1 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF3552 PF12072.8 KIK57820.1 - 0.025 14.0 5.2 0.061 12.7 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Lzipper-MIP1 PF14389.6 KIK57820.1 - 0.041 14.2 0.6 1.3 9.4 0.0 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1090 PF06476.12 KIK57820.1 - 0.54 10.4 3.1 10 6.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) tRNA-synt_2d PF01409.20 KIK57821.1 - 1.5e-45 155.6 0.4 6.4e-25 88.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KIK57821.1 - 5.3e-13 49.2 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 KIK57822.1 - 2.1e-44 151.1 0.0 2.8e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 GrpE FTHFS PF01268.19 KIK57823.1 - 1.1e-257 855.7 0.0 1.7e-257 855.1 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KIK57823.1 - 1.7e-66 222.5 0.2 4.5e-66 221.1 0.2 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KIK57823.1 - 1.2e-36 125.5 0.8 2.9e-36 124.2 0.8 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain PNGaseA PF12222.8 KIK57824.1 - 5.1e-133 444.1 0.8 6.8e-133 443.7 0.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_45 PF14947.6 KIK57824.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix Pkinase PF00069.25 KIK57826.1 - 1.3e-09 37.8 0.0 5.5e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57826.1 - 0.00035 20.0 0.0 0.018 14.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase PNGaseA PF12222.8 KIK57827.1 - 2e-126 422.4 1.7 3.3e-126 421.6 1.7 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Prenyltransf PF01255.19 KIK57828.1 - 7.1e-71 238.3 0.0 9e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DDE_Tnp_IS240 PF13610.6 KIK57828.1 - 0.2 11.9 0.0 5.2 7.3 0.0 2.2 1 1 1 2 2 2 0 DDE domain PNGaseA PF12222.8 KIK57830.1 - 3.1e-117 392.1 5.8 4.7e-117 391.5 5.8 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Dimer_Tnp_hAT PF05699.14 KIK57831.1 - 2.5 8.0 7.2 14 5.5 1.3 3.6 2 1 1 3 3 3 0 hAT family C-terminal dimerisation region Pmp3 PF01679.17 KIK57832.1 - 4.4e-17 62.0 3.1 6.1e-17 61.6 3.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 KIK57832.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal BT1 PF03092.16 KIK57832.1 - 0.46 8.6 0.6 0.65 8.2 0.6 1.2 1 0 0 1 1 1 0 BT1 family zf-C2H2 PF00096.26 KIK57833.1 - 1.3e-21 75.8 26.4 3e-05 24.2 1.4 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK57833.1 - 2.5e-19 68.7 26.6 7.3e-07 29.3 1.9 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK57833.1 - 9.1e-12 44.8 22.1 0.0084 16.9 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 KIK57833.1 - 6.8e-06 26.6 5.0 1.2 9.8 0.0 4.2 2 1 2 4 4 4 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KIK57833.1 - 1.3e-05 25.4 0.0 5.1 7.5 0.0 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK57833.1 - 0.00019 21.7 3.7 0.36 11.3 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KIK57833.1 - 0.00056 19.6 15.5 0.081 12.7 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIK57833.1 - 0.011 15.7 2.9 1.2 9.2 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK57833.1 - 0.026 14.8 7.0 1.1 9.6 2.8 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-CGNR PF11706.8 KIK57833.1 - 0.092 12.6 9.1 5.9 6.8 0.2 4.3 4 0 0 4 4 4 0 CGNR zinc finger zf-LYAR PF08790.11 KIK57833.1 - 0.16 11.9 0.9 62 3.6 0.0 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger IBR PF01485.21 KIK57833.1 - 0.43 10.8 5.3 3.4 8.0 0.5 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 KIK57833.1 - 0.71 10.6 12.2 0.39 11.5 2.3 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.12 KIK57833.1 - 3.4 7.7 5.5 23 5.1 0.5 3.3 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 KIK57833.1 - 6.6 6.6 6.9 12 5.8 0.4 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type FBPase PF00316.20 KIK57834.1 - 2.7e-74 248.8 0.3 3.4e-74 248.4 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KIK57834.1 - 2.5e-05 23.9 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family GCIP PF13324.6 KIK57836.1 - 2.4e-37 129.0 0.4 2.4e-37 129.0 0.4 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting DUF4988 PF16378.5 KIK57836.1 - 0.0026 17.4 1.3 0.54 9.9 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function NPV_P10 PF05531.12 KIK57836.1 - 0.061 13.8 4.9 4 8.0 0.0 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Peptidase_M41 PF01434.18 KIK57837.1 - 4.7e-58 196.2 0.1 8.9e-58 195.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIK57837.1 - 3.8e-43 147.1 0.0 1.4e-42 145.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK57837.1 - 1.6e-11 43.8 0.2 4.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KIK57837.1 - 2.5e-05 24.3 0.1 0.00017 21.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK57837.1 - 4.7e-05 23.8 0.1 0.0057 17.0 0.1 2.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK57837.1 - 0.00016 22.0 0.6 0.11 12.7 0.1 3.0 4 0 0 4 4 2 1 AAA domain RuvB_N PF05496.12 KIK57837.1 - 0.00036 20.3 0.0 0.00094 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KIK57837.1 - 0.00046 19.5 0.3 0.0038 16.5 0.1 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 KIK57837.1 - 0.0066 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK57837.1 - 0.013 15.6 0.1 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK57837.1 - 0.026 15.1 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK57837.1 - 0.037 13.2 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 KIK57837.1 - 0.04 13.3 0.2 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 KIK57837.1 - 0.04 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK57837.1 - 0.048 13.0 2.3 0.051 13.0 0.4 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KIK57837.1 - 0.055 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KIK57837.1 - 0.061 13.1 0.3 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KIK57837.1 - 0.089 12.1 0.4 0.22 10.8 0.4 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KIK57837.1 - 0.091 12.3 4.6 0.21 11.1 0.6 2.8 2 1 1 3 3 3 0 AAA domain TsaE PF02367.17 KIK57837.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIK57837.1 - 0.12 12.3 2.3 0.19 11.6 0.1 2.4 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.26 KIK57837.1 - 0.15 11.8 0.2 0.65 9.7 0.2 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain DEAD_2 PF06733.15 KIK57838.1 - 1.7e-51 174.3 0.0 2.7e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KIK57838.1 - 7.2e-45 153.0 1.9 6.6e-39 133.6 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KIK57838.1 - 1.3e-43 149.1 0.0 2.5e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KIK57838.1 - 0.00041 20.4 0.1 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NAD_binding_6 PF08030.12 KIK57839.1 - 2.1e-23 83.2 0.0 3.3e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KIK57839.1 - 1.2e-17 64.2 3.4 4.1e-17 62.5 3.4 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK57839.1 - 9.8e-15 54.6 0.0 5.6e-14 52.2 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain Cellulase PF00150.18 KIK57840.1 - 1.2e-15 57.8 1.2 5.1e-15 55.6 1.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KIK57840.1 - 0.0014 18.4 0.4 0.24 11.0 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KIK57840.1 - 0.0014 17.8 0.1 0.0093 15.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KIK57840.1 - 0.0048 16.3 1.3 0.025 13.9 0.3 2.2 2 1 0 2 2 2 1 Beta-galactosidase TPR_12 PF13424.6 KIK57841.1 - 1e-05 25.7 7.5 0.14 12.5 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK57841.1 - 0.0048 16.9 0.1 3.4 8.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KIK57841.1 - 0.011 15.8 0.1 2.3 8.3 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 KIK57841.1 - 0.012 15.8 0.1 51 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 KIK57841.1 - 0.017 14.9 0.0 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 KIK57841.1 - 8 7.2 13.2 2.2 9.0 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Pro-kuma_activ PF09286.11 KIK57842.1 - 5.2e-35 120.8 0.1 8.5e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK57842.1 - 9.1e-07 28.4 0.1 1.5e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Subtilase family MtN3_slv PF03083.16 KIK57844.1 - 0.043 13.9 2.7 0.048 13.7 2.7 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange HSDR_N PF04313.14 KIK57846.1 - 0.00063 19.8 0.1 0.00084 19.3 0.1 1.2 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N_2 PF13588.6 KIK57846.1 - 0.0089 16.0 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) AOX PF01786.17 KIK57847.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase DUF3780 PF12635.7 KIK57850.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) zf-H2C2_2 PF13465.6 KIK57855.1 - 0.099 13.1 1.0 0.099 13.1 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DUF1936 PF09151.10 KIK57855.1 - 1.4 8.9 3.3 1.9 8.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) G-alpha PF00503.20 KIK57856.1 - 2.8e-121 405.0 0.1 3.3e-121 404.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK57856.1 - 5.4e-16 58.5 0.9 4.6e-11 42.5 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK57856.1 - 0.00038 19.9 0.8 0.025 14.0 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK57856.1 - 0.022 14.9 0.6 6.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 KIK57856.1 - 0.039 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 KIK57856.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK57856.1 - 0.075 13.1 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK57856.1 - 0.085 12.4 0.0 3.4 7.2 0.0 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KIK57856.1 - 0.094 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family CoA_transf_3 PF02515.17 KIK57859.1 - 3.4e-43 148.2 0.0 4.9e-39 134.5 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III EF-hand_7 PF13499.6 KIK57859.1 - 0.074 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF202 PF02656.15 KIK57860.1 - 2.4e-17 63.1 0.3 2.4e-17 63.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Colicin_M PF14859.6 KIK57860.1 - 0.039 13.1 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Colicin M DUF3784 PF12650.7 KIK57860.1 - 0.26 11.5 10.8 0.22 11.7 9.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) DUF3671 PF12420.8 KIK57860.1 - 0.66 10.1 7.6 0.75 9.9 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function 7tm_1 PF00001.21 KIK57860.1 - 0.87 8.9 6.6 1 8.6 6.6 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Golgin_A5 PF09787.9 KIK57860.1 - 2.3 7.6 4.4 3.1 7.2 4.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ribosomal_L33 PF00471.20 KIK57861.1 - 6.1e-08 33.0 0.0 7.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 KIK57861.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Orn_Arg_deC_N PF02784.16 KIK57864.1 - 8.4e-67 225.1 0.0 1e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIK57864.1 - 9.3e-11 41.8 0.0 1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain adh_short PF00106.25 KIK57865.1 - 1.2e-23 83.6 0.1 3.2e-22 78.9 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK57865.1 - 2.9e-16 59.7 0.0 3.4e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIK57865.1 - 1e-07 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK57865.1 - 3.7e-05 23.7 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK57865.1 - 0.062 12.8 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KIK57865.1 - 0.13 11.6 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FMO-like PF00743.19 KIK57866.1 - 1.3e-17 63.5 0.1 7.3e-15 54.4 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK57866.1 - 1.2e-16 60.8 0.0 1e-15 57.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK57866.1 - 5.2e-13 48.9 0.1 1.5e-09 37.6 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK57866.1 - 6.5e-12 45.2 0.0 8.9e-09 34.9 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK57866.1 - 4e-07 30.5 0.3 0.011 16.2 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK57866.1 - 9.7e-06 25.7 0.2 0.0007 19.8 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK57866.1 - 0.00066 19.1 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK57866.1 - 0.001 18.4 0.5 0.0047 16.2 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Mur_ligase PF01225.25 KIK57866.1 - 0.0097 16.2 0.0 2 8.8 0.0 2.5 2 0 0 2 2 2 1 Mur ligase family, catalytic domain GIDA PF01134.22 KIK57866.1 - 0.016 14.3 0.1 0.2 10.7 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIK57866.1 - 0.029 13.4 0.0 0.072 12.1 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KIK57866.1 - 0.036 14.1 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIK57866.1 - 0.056 12.5 0.5 0.11 11.6 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KIK57866.1 - 0.061 12.7 0.7 2.4 7.4 0.7 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KIK57866.1 - 0.069 12.7 0.0 1.5 8.3 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK57866.1 - 0.14 12.1 0.2 6.7 6.7 0.0 3.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding p450 PF00067.22 KIK57867.1 - 3.4e-46 157.9 0.0 8e-42 143.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIK57868.1 - 2e-50 171.9 0.0 3.9e-50 171.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KIK57869.1 - 7e-21 74.6 0.1 1.2e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK57869.1 - 2.6e-07 30.5 0.0 9.6e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIK57869.1 - 4.7e-07 30.9 0.0 1.3e-06 29.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK57869.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Cys_Met_Meta_PP PF01053.20 KIK57870.1 - 2.6e-19 69.0 0.0 3.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK57870.1 - 0.00055 19.2 0.0 0.0023 17.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Orn_Arg_deC_N PF02784.16 KIK57871.1 - 5.9e-62 209.2 0.0 8.1e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIK57871.1 - 7.6e-12 45.3 0.0 1.2e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Acetyltransf_10 PF13673.7 KIK57872.1 - 4.8e-05 23.3 0.0 8.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK57872.1 - 0.00014 22.2 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK57872.1 - 0.00091 19.3 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK57872.1 - 0.0091 16.2 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family AA_permease_2 PF13520.6 KIK57873.1 - 6.8e-40 137.2 49.0 1.2e-39 136.4 49.0 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK57873.1 - 2.7e-32 112.0 38.7 3.4e-32 111.7 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK57874.1 - 3.6e-37 128.2 50.8 4.7e-37 127.8 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK57874.1 - 3e-15 55.8 39.5 3.8e-15 55.4 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2651 PF10852.8 KIK57874.1 - 0.59 10.8 7.1 6 7.5 0.6 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) NmrA PF05368.13 KIK57878.1 - 4.7e-09 36.1 0.0 9.9e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KIK57878.1 - 6.5e-09 35.6 0.0 0.00038 20.0 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK57878.1 - 2.1e-08 34.3 0.0 3.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK57878.1 - 0.0065 15.7 0.0 0.066 12.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KIK57878.1 - 0.0066 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIK57878.1 - 0.026 13.5 0.0 0.075 12.0 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ketoacyl-synt PF00109.26 KIK57881.1 - 1.1e-74 251.2 0.0 8.1e-74 248.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK57881.1 - 5.9e-71 239.6 0.2 1.1e-70 238.7 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIK57881.1 - 2.1e-55 187.4 0.0 7.1e-55 185.7 0.0 2.0 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.22 KIK57881.1 - 1.8e-36 124.7 0.5 7.1e-36 122.8 0.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIK57881.1 - 4.9e-12 46.3 0.0 1.8e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIK57881.1 - 6.8e-12 45.6 0.0 3.2e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.6 KIK57881.1 - 3.1e-10 39.8 0.0 7e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KIK57881.1 - 0.00021 20.8 0.2 0.0006 19.2 0.2 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 KIK57881.1 - 0.00082 18.9 0.1 0.26 10.7 0.0 3.8 3 1 0 3 3 3 1 short chain dehydrogenase Pkinase_Tyr PF07714.17 KIK57884.1 - 4.3e-10 39.3 0.0 4.8e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK57884.1 - 1.7e-06 27.6 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK57885.1 - 4.4e-13 49.1 0.0 7.2e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK57885.1 - 2.9e-11 43.2 0.0 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SIR4_SID PF16991.5 KIK57889.1 - 0.016 15.3 1.1 0.029 14.4 1.1 1.5 1 0 0 1 1 1 0 Sir4 SID domain DUF4258 PF14076.6 KIK57889.1 - 0.18 12.2 0.4 0.35 11.3 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) Cas_St_Csn2 PF16813.5 KIK57890.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St CE2_N PF17996.1 KIK57892.1 - 0.00075 19.5 0.6 0.031 14.3 0.0 2.7 2 1 0 2 2 2 1 Carbohydrate esterase 2 N-terminal TMEM154 PF15102.6 KIK57892.1 - 0.076 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family MatE PF01554.18 KIK57893.1 - 1.5e-42 145.0 28.2 5.7e-23 81.3 6.6 3.4 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KIK57893.1 - 3.7e-07 30.3 0.7 3.7e-07 30.3 0.7 3.7 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 KIK57893.1 - 0.001 17.8 3.3 0.001 17.8 3.3 2.1 2 0 0 2 2 2 1 Lipid II flippase MurJ Spec3 PF15795.5 KIK57893.1 - 0.13 12.8 10.0 1.3 9.6 0.7 3.3 3 0 0 3 3 3 0 Ectodermal ciliogenesis protein G6PD_C PF02781.16 KIK57894.1 - 7.3e-96 320.8 0.0 9.9e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIK57894.1 - 2.7e-50 171.5 0.0 3.7e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain NAD_binding_1 PF00175.21 KIK57895.1 - 2.7e-25 89.1 0.0 5.5e-25 88.1 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK57895.1 - 8.5e-08 32.5 0.0 4.8e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK57895.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.6 KIK57897.1 - 8.1e-42 143.5 49.3 1e-41 143.2 49.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK57897.1 - 1.2e-19 70.3 40.2 1.6e-19 69.9 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease Csm1_N PF18504.1 KIK57898.1 - 0.83 10.0 4.9 0.45 10.9 1.9 2.1 1 1 0 1 1 1 0 Csm1 N-terminal domain OmpH PF03938.14 KIK57898.1 - 2.2 8.6 5.8 5.1 7.4 5.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tropomyosin PF00261.20 KIK57899.1 - 0.0046 16.4 3.0 0.0087 15.4 3.0 1.3 1 0 0 1 1 1 1 Tropomyosin DUF327 PF03885.13 KIK57899.1 - 0.011 15.7 0.3 0.019 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF648 PF04890.13 KIK57899.1 - 0.03 14.1 0.4 0.043 13.6 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) TSNAXIP1_N PF15739.5 KIK57899.1 - 0.075 13.4 3.0 0.13 12.6 3.0 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Peptidase_M75 PF09375.10 KIK57899.1 - 0.087 12.3 0.7 0.15 11.5 0.7 1.4 1 0 0 1 1 1 0 Imelysin TetR_C_27 PF17935.1 KIK57899.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HR1 PF02185.16 KIK57899.1 - 0.62 10.2 7.6 0.26 11.4 3.0 2.3 2 1 0 2 2 2 0 Hr1 repeat G6PD_C PF02781.16 KIK57900.1 - 2.5e-86 289.5 0.0 2.3e-56 191.1 0.0 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIK57900.1 - 6.5e-51 173.5 0.0 9.4e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain NAD_binding_1 PF00175.21 KIK57901.1 - 3.3e-24 85.6 0.0 5.4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK57901.1 - 1.8e-06 28.2 0.0 7.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK57901.1 - 0.0047 17.1 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_10 PF13374.6 KIK57901.1 - 0.097 12.6 0.4 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Zincin_2 PF10103.9 KIK57902.1 - 0.0053 16.1 0.3 0.011 15.0 0.3 1.4 1 0 0 1 1 1 1 Zincin-like metallopeptidase CxC2 PF18803.1 KIK57904.1 - 8.4e-22 77.4 1.1 1.4e-21 76.6 1.1 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases RecQ5 PF06959.11 KIK57905.1 - 0.0034 17.4 0.4 0.0045 17.0 0.4 1.1 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) DpnI_C PF17726.1 KIK57906.1 - 0.036 14.2 0.1 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Dam-replacing HTH domain DUF905 PF06006.12 KIK57908.1 - 0.12 12.4 0.8 7.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) PWWP PF00855.17 KIK57909.1 - 4.8e-19 68.6 0.8 8.9e-19 67.7 0.0 1.9 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 KIK57909.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Ndc1_Nup PF09531.10 KIK57909.1 - 2.6 6.6 4.7 3.3 6.3 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2849 PF11011.8 KIK57909.1 - 2.9 8.6 5.9 1.5 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) RR_TM4-6 PF06459.12 KIK57909.1 - 6.5 6.5 11.9 13 5.5 11.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NIF PF03031.18 KIK57911.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DUF1308 PF07000.11 KIK57912.1 - 0.018 15.0 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Tannase PF07519.11 KIK57913.1 - 9.7e-121 403.9 0.3 1.1e-120 403.7 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_A4 PF01828.17 KIK57914.1 - 1.5e-66 223.8 18.2 1.9e-66 223.5 18.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF2888 PF11135.8 KIK57914.1 - 0.086 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Peptidase_A4 PF01828.17 KIK57915.1 - 1.9e-64 217.0 17.5 1.9e-64 217.0 17.5 1.4 2 0 0 2 2 2 1 Peptidase A4 family Peptidase_A4 PF01828.17 KIK57916.1 - 1.3e-67 227.3 14.0 1.6e-67 227.0 14.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family Mfa1 PF17445.2 KIK57916.1 - 1.2 9.2 7.6 1.3 9.1 1.2 2.9 2 0 0 2 2 2 0 Mating factor A1 OPT PF03169.15 KIK57919.1 - 5.9e-104 348.9 41.8 1.7e-103 347.4 41.8 1.7 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DAHP_synth_2 PF01474.16 KIK57920.1 - 0.19 10.2 0.1 0.26 9.7 0.1 1.1 1 0 0 1 1 1 0 Class-II DAHP synthetase family FAD_binding_4 PF01565.23 KIK57921.1 - 9.1e-32 109.7 1.8 1.5e-31 109.0 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK57921.1 - 2.9e-14 52.9 0.3 2.9e-14 52.9 0.3 1.8 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.23 KIK57922.1 - 7.5e-30 103.5 1.2 1.2e-29 102.9 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK57922.1 - 1.6e-12 47.3 2.4 1.6e-12 47.3 2.4 2.3 2 0 0 2 2 2 1 Berberine and berberine like Abhydrolase_3 PF07859.13 KIK57923.1 - 2.3e-24 86.4 0.0 3.8e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK57923.1 - 1.4e-06 27.4 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase PAE PF03283.13 KIK57923.1 - 0.13 11.4 0.8 7.2 5.6 0.0 2.4 2 1 1 3 3 3 0 Pectinacetylesterase BBE PF08031.12 KIK57925.1 - 1.9e-12 47.1 2.5 1.9e-12 47.1 2.5 2.2 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.23 KIK57925.1 - 6.6e-12 45.3 0.2 1.1e-11 44.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.21 KIK57926.1 - 4.9e-71 239.3 0.1 5.5e-71 239.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 KIK57927.1 - 8.3e-07 29.0 14.7 8.3e-07 29.0 14.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KIK57928.1 - 6.4e-30 103.3 0.6 2.3e-29 101.5 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK57928.1 - 4.1e-12 46.2 0.0 5.6e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KIK57928.1 - 0.0082 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KIK57928.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FANCL_C PF11793.8 KIK57928.1 - 0.066 13.4 0.5 0.14 12.4 0.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain ADH_N_assoc PF13823.6 KIK57928.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Aldo_ket_red PF00248.21 KIK57929.1 - 6.7e-73 245.4 0.2 7.6e-73 245.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Herpes_US9 PF06072.11 KIK57930.1 - 0.0072 16.2 1.2 0.053 13.4 0.4 2.4 2 0 0 2 2 2 1 Alphaherpesvirus tegument protein US9 ERGIC_N PF13850.6 KIK57930.1 - 8.5 6.8 7.0 1.2 9.6 0.4 2.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Aldo_ket_red PF00248.21 KIK57931.1 - 2e-72 243.9 0.1 2.2e-72 243.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 2OG-FeII_Oxy_3 PF13640.6 KIK57933.1 - 3.7e-08 34.1 0.0 5.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KIK57933.1 - 0.095 12.9 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KIK57933.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Pkinase_Tyr PF07714.17 KIK57934.1 - 8.1e-11 41.7 0.0 3.5e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK57934.1 - 2.2e-10 40.3 0.0 5e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Neurensin PF14927.6 KIK57936.1 - 0.051 13.3 1.3 0.074 12.8 0.3 1.7 1 1 0 1 1 1 0 Neurensin DUF4870 PF09685.10 KIK57936.1 - 3.1 8.0 10.4 1 9.5 6.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Sec2p PF06428.11 KIK57937.1 - 6.3e-10 38.9 13.3 6.3e-10 38.9 13.3 3.3 3 1 1 4 4 3 1 GDP/GTP exchange factor Sec2p MRP-S26 PF14943.6 KIK57937.1 - 4.9e-05 23.3 6.7 8.6e-05 22.5 6.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 SKA1 PF07160.12 KIK57937.1 - 0.37 10.6 7.6 0.72 9.7 6.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 KIK57937.1 - 0.75 9.1 6.8 36 3.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KIK57937.1 - 0.83 9.7 3.2 8.1 6.5 1.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 KIK57937.1 - 1.1 9.6 14.5 2.8 8.3 14.5 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FemAB PF02388.16 KIK57937.1 - 1.3 7.8 5.5 2.1 7.1 5.5 1.2 1 0 0 1 1 1 0 FemAB family Golgin_A5 PF09787.9 KIK57937.1 - 1.4 8.3 14.3 2.7 7.4 13.6 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 KIK57937.1 - 1.5 8.9 22.8 0.8 9.8 19.4 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KIK57937.1 - 1.8 8.8 6.0 22 5.4 1.0 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.11 KIK57937.1 - 2 7.2 18.1 79 2.0 0.0 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KIK57937.1 - 2.2 8.4 24.6 19 5.4 0.0 4.2 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF1640 PF07798.11 KIK57937.1 - 2.4 8.2 16.4 0.49 10.4 12.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) BRE1 PF08647.11 KIK57937.1 - 6.9 6.8 16.9 1.4 9.1 12.2 2.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase COG2 PF06148.11 KIK57937.1 - 8 6.6 17.6 0.47 10.5 8.1 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KIK57937.1 - 8.1 6.9 11.1 7.5 7.0 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 KIK57937.1 - 8.8 5.3 9.5 17 4.4 9.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 KIK57937.1 - 9.1 4.8 10.2 18 3.8 9.6 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A SPC25 PF06703.11 KIK57940.1 - 0.18 11.6 4.1 0.27 11.0 2.3 2.3 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) NACHT PF05729.12 KIK57943.1 - 6.6e-07 29.4 0.1 4.8e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK57943.1 - 0.0006 19.1 0.0 0.0083 15.3 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 KIK57943.1 - 0.0013 18.7 0.1 0.1 12.6 0.1 2.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK57943.1 - 0.0034 16.7 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK57943.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK57943.1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KIK57943.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIK57943.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK57943.1 - 0.072 13.5 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Cactin_mid PF10312.9 KIK57943.1 - 0.16 11.7 1.2 0.16 11.7 0.2 1.5 2 0 0 2 2 2 0 Conserved mid region of cactin Zeta_toxin PF06414.12 KIK57943.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ank_4 PF13637.6 KIK57944.1 - 4.6e-20 71.7 2.6 2.9e-08 34.1 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK57944.1 - 2.9e-15 56.6 1.9 7.9e-07 29.6 0.2 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK57944.1 - 7e-11 41.4 3.0 0.0058 17.0 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIK57944.1 - 7.2e-11 42.0 6.7 0.0026 18.1 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KIK57944.1 - 7.2e-09 35.7 2.1 8.2e-05 22.8 0.2 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KIK57944.1 - 0.022 14.6 0.1 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain TbpB_B_D PF01298.18 KIK57944.1 - 0.18 12.2 2.9 0.84 10.0 1.0 2.5 1 1 1 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B FAD_binding_4 PF01565.23 KIK57945.1 - 8e-19 67.8 1.2 2.4e-18 66.2 0.7 2.0 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KIK57945.1 - 7.7e-09 35.5 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M24 PF00557.24 KIK57946.1 - 2.4e-44 151.6 0.0 3.3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KIK57946.1 - 7.8e-35 120.3 0.0 1.3e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KIK57946.1 - 4.4e-21 74.7 0.5 1.4e-20 73.1 0.5 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIK57946.1 - 1.5e-12 48.3 0.0 4.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M2 PF01401.18 KIK57947.1 - 0.069 11.8 2.1 0.092 11.4 2.1 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF4050 PF13259.6 KIK57947.1 - 0.13 12.5 10.5 0.028 14.8 6.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Hydin_ADK PF17213.3 KIK57947.1 - 0.47 10.7 6.5 1.4 9.1 6.3 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain EIID-AGA PF03613.14 KIK57949.1 - 0.1 11.7 3.9 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component DUF2955 PF11168.8 KIK57949.1 - 0.3 10.9 8.3 0.25 11.2 1.4 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2955) p450 PF00067.22 KIK57951.1 - 1.6e-73 248.1 0.0 4.6e-73 246.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Herpes_BLRF2 PF05812.12 KIK57951.1 - 0.039 14.1 0.1 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein FAD_binding_4 PF01565.23 KIK57952.1 - 1.3e-21 76.8 2.5 1.6e-21 76.5 1.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KIK57952.1 - 3.1e-08 33.6 0.0 6.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Bystin PF05291.11 KIK57952.1 - 0.27 10.5 0.1 0.43 9.8 0.1 1.2 1 0 0 1 1 1 0 Bystin Ndc1_Nup PF09531.10 KIK57955.1 - 1.4 7.5 6.7 1.9 7.1 6.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NAD_binding_1 PF00175.21 KIK57956.1 - 7.9e-22 78.0 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK57956.1 - 6.4e-09 36.1 0.0 5.7e-07 29.8 0.0 2.7 2 1 1 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK57956.1 - 0.0054 16.9 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain HTH_31 PF13560.6 KIK57956.1 - 0.0085 16.4 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Pec_lyase_C PF00544.19 KIK57960.1 - 5.7e-31 107.7 8.2 7.7e-31 107.3 8.2 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIK57960.1 - 2.2e-08 34.1 10.4 1.9e-06 27.8 3.7 2.4 2 1 0 2 2 2 2 Right handed beta helix region DUF2470 PF10615.9 KIK57961.1 - 1.5e-19 70.4 0.0 2.6e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KIK57961.1 - 2.9e-07 30.7 5.0 4.5e-07 30.1 5.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) p450 PF00067.22 KIK57962.1 - 4e-44 151.1 0.0 6.2e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribo_biogen_C PF04034.13 KIK57962.1 - 0.057 13.2 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal Mid2 PF04478.12 KIK57963.1 - 0.0034 17.2 0.2 0.0034 17.2 0.2 2.2 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 KIK57963.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 KIK57963.1 - 0.038 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 KIK57963.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gly-zipper_Omp PF13488.6 KIK57963.1 - 1.8 8.6 11.1 0.046 13.7 3.1 2.1 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KIK57963.1 - 3.9 7.4 11.8 0.045 13.6 2.0 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Arf PF00025.21 KIK57964.1 - 1.4e-24 86.5 0.0 2.3e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK57964.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK57964.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IBR PF01485.21 KIK57966.1 - 1.3e-12 47.7 21.1 6.6e-09 35.9 17.2 4.5 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIK57966.1 - 0.0014 18.4 5.1 0.0014 18.4 5.1 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK57966.1 - 0.0078 16.2 5.6 0.0078 16.2 5.6 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK57966.1 - 9.1 6.7 34.8 0.063 13.6 6.6 3.6 3 0 0 3 3 3 0 Ring finger domain Annexin PF00191.20 KIK57970.1 - 3.6e-16 59.0 0.0 3e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Annexin AAA_16 PF13191.6 KIK57975.1 - 0.00064 20.1 0.0 0.00088 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK57975.1 - 0.0012 18.8 0.5 0.0049 16.8 0.5 1.9 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 KIK57975.1 - 0.025 14.5 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 KIK57975.1 - 0.035 14.3 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK57975.1 - 0.05 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KIK57975.1 - 0.054 13.8 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK57975.1 - 0.057 13.3 0.1 0.087 12.7 0.1 1.6 1 1 0 1 1 1 0 NTPase AAA_7 PF12775.7 KIK57975.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HHH_7 PF14635.6 KIK57975.1 - 0.076 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNA_helicase PF00910.22 KIK57975.1 - 0.089 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KIK57975.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 KIK57975.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KIK57975.1 - 0.14 12.6 0.1 0.25 11.8 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GKAP PF03359.13 KIK57976.1 - 0.0018 17.9 0.1 0.0021 17.7 0.1 1.1 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein CCDC106 PF15794.5 KIK57976.1 - 1 9.1 5.2 1.3 8.7 5.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Transketolase_N PF00456.21 KIK57977.1 - 1.6e-15 56.9 1.5 2.6e-14 52.9 1.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KIK57977.1 - 7.1e-08 32.4 0.0 6.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KIK57977.1 - 1.2e-05 25.1 0.2 3.2e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIK57977.1 - 5.7e-05 22.2 0.0 8.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KIK57977.1 - 0.00043 20.1 0.1 0.0019 18.0 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NACHT PF05729.12 KIK57978.1 - 0.00011 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK57978.1 - 0.00023 21.6 0.0 0.00031 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK57978.1 - 0.0075 16.6 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 KIK57978.1 - 0.033 14.1 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK57978.1 - 0.038 13.1 0.1 0.054 12.6 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK57978.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK57978.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK57978.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KIK57978.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 KIK57978.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK57978.1 - 0.22 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein APS_kinase PF01583.20 KIK57978.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KIK57979.1 - 5.1e-06 26.5 0.2 3.8e-05 23.7 0.1 1.9 1 1 1 2 2 2 1 NACHT domain TniB PF05621.11 KIK57979.1 - 0.076 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DLEU7 PF15760.5 KIK57979.1 - 0.18 11.3 0.2 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 Leukemia-associated protein 7 Radial_spoke_3 PF06098.11 KIK57980.1 - 0.23 10.7 0.0 0.23 10.7 0.0 2.6 3 1 1 4 4 4 0 Radial spoke protein 3 DUF829 PF05705.14 KIK57981.1 - 2.8e-25 89.6 0.0 5.5e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 KIK57981.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 KIK57981.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF829 PF05705.14 KIK57983.1 - 6.8e-47 160.4 0.0 9.6e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 KIK57983.1 - 0.029 13.9 0.0 0.068 12.6 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 KIK57983.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Cyclin_N PF00134.23 KIK57986.1 - 5.7e-13 48.7 0.0 1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK57986.1 - 9.6e-06 26.0 0.0 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin DUF4604 PF15377.6 KIK57988.1 - 7.9e-19 68.7 6.6 1.3e-18 68.0 6.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) NACHT PF05729.12 KIK57989.1 - 2.3e-13 50.4 0.0 5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK57989.1 - 0.00074 19.9 0.0 0.0021 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK57989.1 - 0.0015 18.9 0.0 0.07 13.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KIK57989.1 - 0.015 15.7 0.0 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK57989.1 - 0.042 14.1 0.0 0.16 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK57989.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TniB PF05621.11 KIK57989.1 - 0.087 12.2 0.0 0.63 9.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein ATPase_2 PF01637.18 KIK57989.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SNARE PF05739.19 KIK57990.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SNARE domain HrpB7 PF09486.10 KIK57990.1 - 0.051 14.0 2.5 0.33 11.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.16 KIK57990.1 - 0.67 10.2 4.6 2.8 8.2 0.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Haspin_kinase PF12330.8 KIK57991.1 - 0.0049 15.9 0.0 0.0062 15.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK57991.1 - 0.037 13.9 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GST_N PF02798.20 KIK57993.1 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK57993.1 - 4.6e-09 36.6 0.0 8.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK57993.1 - 4.2e-08 33.4 0.0 8.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK57993.1 - 3e-07 30.5 0.0 5.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK57993.1 - 0.00018 21.5 0.0 0.0004 20.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain HN PF00423.19 KIK57994.1 - 0.03 13.2 0.1 0.048 12.4 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Spem1 PF15670.5 KIK57994.1 - 0.074 12.6 0.5 0.12 11.9 0.5 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Herpes_gI PF01688.17 KIK57996.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I FYTT PF07078.11 KIK57996.1 - 0.11 11.8 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Forty-two-three protein MatE PF01554.18 KIK58000.1 - 5.6e-47 159.4 36.1 8e-28 97.1 10.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KIK58000.1 - 1.2e-05 25.4 10.0 1.2e-05 25.4 10.0 4.2 2 1 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Phage_Gp23 PF10669.9 KIK58000.1 - 0.27 11.6 0.9 0.49 10.7 0.4 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) UPF0242 PF06785.11 KIK58000.1 - 0.44 10.6 1.8 0.63 10.1 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Gti1_Pac2 PF09729.9 KIK58001.1 - 4e-36 124.8 0.0 1e-27 97.4 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Ferric_reduct PF01794.19 KIK58003.1 - 1.2e-18 67.5 7.4 1.2e-18 67.5 7.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK58003.1 - 2.5e-09 37.4 0.0 8.4e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK58003.1 - 5.6e-07 29.6 0.0 2e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain EmrE PF13536.6 KIK58003.1 - 0.0091 15.6 0.6 0.023 14.3 0.6 1.6 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter Ni_hydr_CYTB PF01292.20 KIK58003.1 - 1.8 8.2 9.2 0.053 13.1 1.8 2.0 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Gti1_Pac2 PF09729.9 KIK58005.1 - 4.5e-26 92.0 0.0 4.9e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family COesterase PF00135.28 KIK58006.1 - 5e-81 273.1 0.0 6.4e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK58006.1 - 1.8e-07 31.2 0.9 2.2e-06 27.7 0.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK58006.1 - 0.045 14.3 0.4 0.084 13.5 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.28 KIK58008.1 - 1.8e-83 281.2 0.0 2.6e-83 280.6 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK58008.1 - 2.7e-06 27.4 0.4 3.2e-05 23.9 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold RL11D PF11088.8 KIK58008.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 COesterase PF00135.28 KIK58009.1 - 3.4e-84 283.6 0.0 4.3e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK58009.1 - 3.8e-07 30.2 0.9 4.8e-06 26.6 0.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK58009.1 - 0.018 15.7 0.2 0.033 14.8 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kdo PF06293.14 KIK58010.1 - 0.0075 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_10 PF00331.20 KIK58011.1 - 6.2e-100 334.4 0.0 7e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Arv1 PF04161.13 KIK58012.1 - 2.2e-38 132.5 0.0 3.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family zf-ZPR1 PF03367.13 KIK58013.1 - 2e-112 372.3 0.0 4.6e-57 192.3 0.0 2.5 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KIK58013.1 - 0.0017 18.4 1.3 2 8.5 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIK58013.1 - 0.0018 18.2 3.1 0.48 10.5 0.1 3.0 2 1 0 2 2 2 2 Double zinc ribbon DUF2688 PF10892.8 KIK58013.1 - 0.043 13.3 3.3 2.6 7.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) Zn-ribbon_8 PF09723.10 KIK58013.1 - 0.054 13.6 4.0 3 8.0 0.0 3.5 3 1 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KIK58013.1 - 0.085 12.9 0.9 7.1 6.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbons Ribosomal_L37e PF01907.19 KIK58013.1 - 0.12 12.5 5.8 1.3 9.3 0.0 3.6 4 0 0 4 4 4 0 Ribosomal protein L37e zinc_ribbon_2 PF13240.6 KIK58013.1 - 0.13 12.0 12.1 9.5 6.1 0.5 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF5627 PF18620.1 KIK58014.1 - 0.01 15.7 0.6 0.02 14.7 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5627) Crystall_2 PF09076.10 KIK58014.1 - 0.11 12.4 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Beta/Gamma crystallin HgmA PF04209.13 KIK58015.1 - 1.4e-154 514.9 0.6 6e-139 463.4 0.1 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase COX2-transmemb PF09125.10 KIK58016.1 - 0.015 15.1 1.3 1 9.2 0.0 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Ring_hydroxyl_A PF00848.19 KIK58017.1 - 0.19 11.7 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) MatE PF01554.18 KIK58018.1 - 1.9e-12 47.1 33.7 1.8e-07 31.0 7.9 3.9 2 1 1 3 3 3 2 MatE UPF0242 PF06785.11 KIK58018.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Gti1_Pac2 PF09729.9 KIK58022.1 - 0.044 13.9 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TPR_10 PF13374.6 KIK58024.1 - 1.1e-61 203.2 2.6 3.4e-15 55.4 0.0 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58024.1 - 2.7e-43 146.1 7.0 1.2e-17 64.0 0.3 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58024.1 - 1.1e-15 56.4 4.4 0.0029 17.5 0.1 4.5 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58024.1 - 2.2e-15 55.5 8.9 0.00044 20.2 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58024.1 - 7.6e-13 47.7 5.4 0.043 13.7 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58024.1 - 3.7e-10 39.7 0.6 6.7e-10 38.8 0.6 1.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 KIK58024.1 - 8.9e-09 35.1 6.6 0.5 10.9 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58024.1 - 1.8e-07 30.8 3.5 0.28 11.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58024.1 - 2e-07 31.4 0.6 0.98 10.0 0.1 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat DUF4919 PF16266.5 KIK58024.1 - 4e-05 23.7 0.5 0.4 10.6 0.0 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4919) DUF1897 PF09005.10 KIK58024.1 - 0.0013 18.2 0.4 6.1 6.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1897) TPR_14 PF13428.6 KIK58024.1 - 0.0036 18.0 0.1 1.2e+02 3.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fibritin_C PF07921.12 KIK58024.1 - 0.0072 16.4 0.0 27 5.0 0.0 3.8 1 1 2 4 4 4 0 Fibritin C-terminal region SERTA PF06031.13 KIK58024.1 - 0.011 15.4 2.1 28 4.5 0.0 4.2 4 0 0 4 4 4 0 SERTA motif TPR_16 PF13432.6 KIK58024.1 - 0.013 16.1 0.4 8.2 7.2 0.1 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat DASH_Dam1 PF08653.10 KIK58024.1 - 0.05 13.4 0.8 25 4.8 0.0 4.1 4 1 0 4 4 4 0 DASH complex subunit Dam1 F1F0-ATPsyn_F PF10791.9 KIK58024.1 - 0.064 13.7 0.0 29 5.2 0.0 3.1 1 1 2 3 3 3 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi NSP2-B_epitope PF14757.6 KIK58024.1 - 0.088 12.5 0.1 13 5.4 0.0 2.7 1 1 2 3 3 3 0 Immunogenic region of nsp2 protein of arterivirus polyprotein TPR_3 PF07720.12 KIK58024.1 - 0.33 11.0 2.6 7.3 6.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_19 PF13245.6 KIK58025.1 - 0.026 14.9 0.1 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK58025.1 - 0.14 12.4 0.0 0.9 9.8 0.0 2.4 2 1 1 3 3 3 0 AAA domain DUF1645 PF07816.11 KIK58026.1 - 0.0038 17.8 0.0 0.0052 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) APH PF01636.23 KIK58027.1 - 2e-05 24.6 0.4 0.00051 20.0 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIK58027.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK58027.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK58027.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 KIK58027.1 - 0.13 11.5 0.0 0.41 9.9 0.0 1.7 1 1 1 2 2 2 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 KIK58027.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_20 PF00728.22 KIK58028.1 - 2.6e-20 73.1 0.0 7.7e-18 65.0 0.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KIK58028.1 - 6e-05 23.8 0.0 0.00013 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 TPR_10 PF13374.6 KIK58029.1 - 1.8e-73 240.6 11.4 1.9e-08 33.9 0.0 9.9 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58029.1 - 9.5e-56 186.0 9.2 1.1e-09 38.4 0.0 8.0 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58029.1 - 1.4e-19 69.0 27.0 0.0086 15.9 0.3 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58029.1 - 1.4e-15 56.1 16.5 0.074 13.3 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58029.1 - 1.5e-13 49.7 23.3 0.24 11.6 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK58029.1 - 3.4e-13 49.4 9.3 1.8 8.7 0.0 9.0 9 0 0 9 9 9 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KIK58029.1 - 1.6e-10 40.3 12.2 13 6.1 0.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat YqaH PF17448.2 KIK58029.1 - 6.1e-10 39.3 0.4 0.95 9.8 0.0 6.5 2 2 5 7 7 7 1 Uncharacterized YqaH-like Rapsyn_N PF10579.9 KIK58029.1 - 1.5e-09 37.8 8.8 15 5.8 0.0 8.7 6 2 3 9 9 9 0 Rapsyn N-terminal myristoylation and linker region DUF4188 PF13826.6 KIK58029.1 - 1.3e-08 35.2 3.7 0.13 12.6 0.1 7.1 2 2 5 7 7 7 1 Domain of unknown function (DUF4188) PPR PF01535.20 KIK58029.1 - 1.4e-08 34.4 12.7 3.2 8.2 0.1 8.8 9 0 0 9 9 9 1 PPR repeat TPR_20 PF14561.6 KIK58029.1 - 2.9e-08 33.9 2.4 17 5.9 0.0 7.6 2 2 7 9 9 8 0 Tetratricopeptide repeat DUF3400 PF11880.8 KIK58029.1 - 4.1e-08 32.6 0.1 7 6.3 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF3400) ANAPC3 PF12895.7 KIK58029.1 - 4.6e-08 33.2 4.0 0.12 12.6 0.1 6.3 1 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Foie-gras_1 PF11817.8 KIK58029.1 - 3.5e-06 26.8 8.1 9.7 5.7 0.0 6.6 5 2 0 7 7 7 0 Foie gras liver health family 1 Paf67 PF10255.9 KIK58029.1 - 9e-06 24.9 0.0 5 6.0 0.0 3.8 1 1 3 4 4 4 1 RNA polymerase I-associated factor PAF67 SRP_TPR_like PF17004.5 KIK58029.1 - 1.1e-05 25.4 5.3 16 5.6 0.1 6.8 1 1 5 6 6 6 0 Putative TPR-like repeat R-HINP1I PF11463.8 KIK58029.1 - 2.8e-05 23.7 0.4 30 4.0 0.0 5.9 1 1 6 7 7 7 0 R.HinP1I restriction endonuclease TPR_16 PF13432.6 KIK58029.1 - 0.00011 22.8 3.1 28 5.5 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KIK58029.1 - 0.00026 21.0 6.7 4.6 7.3 0.1 5.1 3 2 2 5 5 5 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_9 PF13371.6 KIK58029.1 - 0.00029 20.9 0.1 24 5.2 0.0 5.9 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58029.1 - 0.00047 20.5 0.0 1.7e+02 3.3 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3395 PF11875.8 KIK58029.1 - 0.0044 16.9 0.0 20 5.0 0.0 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3395) TPR_6 PF13174.6 KIK58029.1 - 0.023 15.3 8.0 26 5.7 0.0 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF5588 PF17826.1 KIK58029.1 - 0.029 13.2 0.8 2.2 7.1 0.0 3.9 2 1 2 5 5 5 0 Family of unknown function (DUF5588) TIG_2 PF18020.1 KIK58029.1 - 0.031 14.9 0.2 1.5e+02 3.1 0.0 4.8 2 2 4 6 6 6 0 TIG domain found in plexin DUF5341 PF17276.2 KIK58029.1 - 0.053 13.7 2.8 23 5.1 0.1 4.2 1 1 3 5 5 5 0 Family of unknown function (DUF5341) DUF3895 PF13034.6 KIK58029.1 - 0.068 13.2 0.1 27 4.9 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3895) ACP_PD PF04336.12 KIK58029.1 - 0.14 12.6 11.2 6.9 7.1 0.5 4.9 1 1 5 6 6 6 0 Acyl carrier protein phosphodiesterase Umbravirus_LDM PF04817.12 KIK58029.1 - 0.19 11.0 0.0 59 2.9 0.0 4.1 5 1 1 6 6 6 0 Umbravirus long distance movement (LDM) family TPR_17 PF13431.6 KIK58029.1 - 0.74 10.3 20.2 74 4.1 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK58029.1 - 0.84 9.4 10.9 8.4 6.2 0.1 5.9 8 0 0 8 8 8 0 TPR repeat SPOB_a PF14689.6 KIK58029.1 - 1.1 9.0 10.2 3.2 7.5 0.0 5.1 6 0 0 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_10 PF13374.6 KIK58035.1 - 1e-119 387.7 25.7 1.2e-09 37.7 0.0 13.4 14 0 0 14 14 13 13 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58035.1 - 5.8e-81 266.8 41.2 1.9e-11 44.1 0.1 11.0 2 1 10 12 12 12 12 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58035.1 - 2.4e-30 102.1 33.7 0.12 12.7 0.0 13.1 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58035.1 - 1.1e-28 97.8 60.0 0.014 15.2 0.3 13.2 13 0 0 13 13 13 11 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK58035.1 - 1.7e-15 56.9 17.2 2.9 8.0 0.0 12.6 4 3 9 13 13 13 2 Rapsyn N-terminal myristoylation and linker region YqaH PF17448.2 KIK58035.1 - 2.4e-14 53.4 2.8 4.5 7.6 0.0 10.0 1 1 12 13 13 13 2 Uncharacterized YqaH-like TPR_2 PF07719.17 KIK58035.1 - 3.4e-14 51.7 50.9 0.56 10.5 0.2 13.1 13 0 0 13 13 13 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK58035.1 - 1.1e-13 51.2 9.4 0.67 10.2 0.1 8.6 2 2 5 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF4188 PF13826.6 KIK58035.1 - 3.9e-12 46.6 11.1 9.8 6.5 0.1 10.0 1 1 7 9 9 9 0 Domain of unknown function (DUF4188) DUF3400 PF11880.8 KIK58035.1 - 1.1e-11 44.1 5.2 14 5.3 0.0 11.4 12 0 0 12 12 12 0 Domain of unknown function (DUF3400) TPR_7 PF13176.6 KIK58035.1 - 2.3e-11 42.9 33.8 1.6 8.9 0.0 12.8 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_20 PF14561.6 KIK58035.1 - 4.5e-11 42.9 16.7 34 4.9 0.0 11.9 1 1 11 12 12 12 0 Tetratricopeptide repeat PPR PF01535.20 KIK58035.1 - 1.3e-10 40.7 17.2 6.3 7.3 0.0 12.3 13 0 0 13 13 13 1 PPR repeat Foie-gras_1 PF11817.8 KIK58035.1 - 2.2e-10 40.6 18.8 16 5.0 0.0 11.5 11 1 0 12 12 12 0 Foie gras liver health family 1 FlbT PF07378.11 KIK58035.1 - 2.6e-10 40.5 20.5 0.69 10.0 0.2 8.7 1 1 10 11 11 11 4 Flagellar protein FlbT Fis1_TPR_C PF14853.6 KIK58035.1 - 4.6e-09 36.2 21.2 0.72 10.0 0.0 11.8 13 0 0 13 13 13 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KIK58035.1 - 3.6e-08 33.8 15.8 5.6 7.5 0.0 9.3 1 1 9 11 11 11 2 Tetratricopeptide repeat LPD22 PF18834.1 KIK58035.1 - 1.6e-07 31.4 0.0 11 6.3 0.0 7.1 4 2 3 8 8 8 0 Large polyvalent protein associated domain 22 DUF5341 PF17276.2 KIK58035.1 - 7.1e-07 29.6 17.7 5.8 7.1 0.0 8.2 2 2 5 9 9 9 1 Family of unknown function (DUF5341) Paf67 PF10255.9 KIK58035.1 - 3.2e-05 23.1 7.1 0.52 9.2 0.1 4.7 1 1 5 6 6 6 3 RNA polymerase I-associated factor PAF67 FapA PF03961.13 KIK58035.1 - 5.6e-05 21.9 13.2 0.052 12.2 0.5 3.9 1 1 3 4 4 4 2 Flagellar Assembly Protein A TPR_4 PF07721.14 KIK58035.1 - 0.00019 21.7 0.0 3.1e+02 2.5 0.0 7.5 10 0 0 10 10 7 0 Tetratricopeptide repeat SeqA_N PF17206.3 KIK58035.1 - 0.0056 16.0 0.0 4.5 6.7 0.0 5.5 10 0 0 10 10 9 1 SeqA protein N-terminal domain CheX PF13690.6 KIK58035.1 - 0.46 10.7 14.8 47 4.3 0.0 7.6 6 4 2 9 9 9 0 Chemotaxis phosphatase CheX ACP_PD PF04336.12 KIK58035.1 - 0.56 10.6 27.1 5.4 7.5 1.0 6.9 1 1 5 8 8 8 0 Acyl carrier protein phosphodiesterase PBP1_TM PF14812.6 KIK58038.1 - 0.078 13.4 19.5 2.1 8.8 11.2 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.8 KIK58038.1 - 3.3 8.2 21.6 0.93 10.0 9.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Anophelin PF10731.9 KIK58038.1 - 7 6.6 7.2 32 4.4 1.4 3.6 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito SPT6_acidic PF14632.6 KIK58038.1 - 8.6 7.0 20.2 20 5.8 0.1 3.5 2 1 0 2 2 2 0 Acidic N-terminal SPT6 NACHT PF05729.12 KIK58040.1 - 1.5e-10 41.3 0.0 1e-09 38.5 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58040.1 - 0.0019 18.6 0.0 0.0049 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK58040.1 - 0.04 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KIK58040.1 - 0.069 13.6 0.0 0.37 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIK58040.1 - 0.083 12.3 0.0 1.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_25 PF13481.6 KIK58040.1 - 0.15 11.6 0.0 1 8.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KIK58040.1 - 0.19 12.0 0.0 3.2 8.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK58040.1 - 0.2 11.6 0.0 7.7 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1479 PF07350.12 KIK58041.1 - 6.4e-126 420.5 0.0 7.6e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KIK58041.1 - 1e-05 25.9 0.0 0.0025 18.1 0.0 2.6 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Tubulin PF00091.25 KIK58042.1 - 1.8e-61 207.8 0.0 2.6e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK58042.1 - 1e-35 122.6 0.0 1.7e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIK58042.1 - 1.4e-05 25.4 3.4 3.5e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KIK58042.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KIK58042.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like NACHT PF05729.12 KIK58043.1 - 5.3e-08 32.9 0.0 3.6e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58043.1 - 0.0014 19.0 0.0 0.0068 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 KIK58043.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK58043.1 - 0.014 15.8 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RHD3 PF05879.12 KIK58043.1 - 0.026 12.7 0.0 0.036 12.2 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) AAA_25 PF13481.6 KIK58043.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIK58043.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK58043.1 - 0.17 12.2 0.0 0.53 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase UPF0016 PF01169.19 KIK58044.1 - 0.11 12.8 4.4 0.077 13.3 1.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 Glyco_hydro_61 PF03443.14 KIK58046.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 DUF410 PF04190.13 KIK58047.1 - 4.1e-72 243.1 0.0 5.1e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) PsiA PF06952.11 KIK58048.1 - 0.18 11.1 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 PsiA protein Sigma_reg_N PF13800.6 KIK58049.1 - 0.03 14.6 0.8 0.062 13.6 0.8 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PsiA PF06952.11 KIK58052.1 - 0.18 11.1 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 PsiA protein MFS_2 PF13347.6 KIK58055.1 - 8.4e-12 44.4 18.9 8.4e-12 44.4 18.9 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KIK58055.1 - 4e-07 29.3 29.2 4e-07 29.3 29.2 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.16 KIK58055.1 - 0.18 10.0 8.9 0.005 15.1 2.4 1.7 2 0 0 2 2 2 0 BT1 family DUF1688 PF07958.11 KIK58056.1 - 1.2e-175 584.3 0.0 1.4e-175 584.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 KIK58056.1 - 1.6e-05 24.6 0.0 0.00055 19.6 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family FAD_binding_4 PF01565.23 KIK58057.1 - 5.4e-22 78.0 1.7 8.8e-22 77.3 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK58057.1 - 4.2e-11 42.8 1.2 9e-11 41.7 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KIK58057.1 - 0.1 12.0 0.1 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding NACHT PF05729.12 KIK58058.1 - 1.6e-13 50.9 0.0 2.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58058.1 - 1.5e-05 25.4 0.0 5.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK58058.1 - 0.0012 19.2 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK58058.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KIK58058.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK58058.1 - 0.029 14.8 0.1 0.15 12.5 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KIK58058.1 - 0.042 13.4 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK58058.1 - 0.049 13.4 0.1 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KIK58058.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KIK58058.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 KIK58058.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KIK58058.1 - 0.25 11.0 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase F-box-like PF12937.7 KIK58061.1 - 0.00015 21.6 0.9 0.00042 20.2 0.9 1.8 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK58061.1 - 0.013 15.4 0.5 0.021 14.8 0.3 1.3 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.33 KIK58061.1 - 0.38 10.7 9.4 0.2 11.6 4.2 2.6 2 1 0 2 2 2 0 F-box domain G6PD_N PF00479.22 KIK58062.1 - 0.12 13.0 0.1 0.56 10.8 0.1 2.0 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Dimer_Tnp_hAT PF05699.14 KIK58066.1 - 0.36 10.6 3.2 17 5.3 0.0 3.0 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 KIK58068.1 - 1.8e-11 44.0 0.0 8.7e-11 41.7 0.0 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_16 PF13191.6 KIK58070.1 - 0.13 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pyr_redox_3 PF13738.6 KIK58071.1 - 1.1e-13 51.1 0.0 2e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK58071.1 - 1.3e-12 47.0 0.0 2.4e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK58071.1 - 3.1e-12 46.3 0.0 8.6e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK58071.1 - 6.4e-09 35.4 0.1 1.6e-05 24.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK58071.1 - 2.8e-06 27.8 0.1 0.0086 16.6 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK58071.1 - 3.4e-05 23.6 0.7 0.04 13.5 0.0 3.4 2 2 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK58071.1 - 9.1e-05 22.6 0.7 0.002 18.3 0.5 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK58071.1 - 0.0013 17.9 0.0 0.24 10.4 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KIK58071.1 - 0.0037 16.6 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KIK58071.1 - 0.0074 16.3 4.6 9.3 6.2 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KIK58071.1 - 0.045 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK58071.1 - 0.083 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIK58071.1 - 0.13 10.9 1.6 0.3 9.7 0.2 2.2 3 0 0 3 3 3 0 HI0933-like protein p450 PF00067.22 KIK58072.1 - 6.3e-52 176.8 0.0 1.1e-51 176.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ATG13 PF10033.9 KIK58073.1 - 3.7e-43 147.9 0.0 5.9e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 A2M PF00207.22 KIK58074.1 - 0.073 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin family Glyco_hydro_47 PF01532.20 KIK58077.1 - 3e-123 412.1 0.0 3.4e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 KIK58077.1 - 0.085 12.4 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus HSBP1 PF06825.12 KIK58079.1 - 4.7e-20 71.2 3.2 6.2e-20 70.8 3.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 FdhE PF04216.12 KIK58079.1 - 0.0024 17.8 0.5 0.0028 17.6 0.5 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Baculo_PEP_C PF04513.12 KIK58079.1 - 0.016 15.2 0.2 0.021 14.9 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BORCS6 PF10157.9 KIK58079.1 - 0.084 13.1 0.4 0.097 12.9 0.4 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 NPV_P10 PF05531.12 KIK58079.1 - 0.11 12.9 0.9 0.23 11.9 0.9 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.21 KIK58080.1 - 3.7e-39 134.7 0.0 5.5e-37 127.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Gti1_Pac2 PF09729.9 KIK58082.1 - 7.2e-50 169.6 4.5 3.9e-48 163.9 1.0 2.6 2 1 0 2 2 2 1 Gti1/Pac2 family Tfb2 PF03849.14 KIK58083.1 - 1.9e-135 451.4 0.0 2.3e-135 451.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KIK58083.1 - 1e-24 86.7 0.9 2.5e-24 85.5 0.4 2.0 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KIK58083.1 - 0.00079 19.6 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Arc_C PF18162.1 KIK58083.1 - 0.085 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Arc C-lobe Ank_4 PF13637.6 KIK58084.1 - 1.1e-19 70.4 0.0 8.4e-14 51.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK58084.1 - 7.9e-18 64.8 0.0 9.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK58084.1 - 1.8e-16 59.8 0.0 8.6e-07 29.1 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK58084.1 - 5.5e-16 58.4 0.0 1.6e-08 34.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK58084.1 - 1.2e-14 53.0 0.0 4.3e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIK58085.1 - 8.5e-16 57.8 0.4 7.6e-06 26.1 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK58085.1 - 4.8e-15 55.7 0.0 7.2e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK58085.1 - 7.1e-15 54.7 0.7 0.0031 17.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KIK58085.1 - 3.3e-14 53.2 0.0 1e-13 51.7 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK58085.1 - 1.6e-12 46.4 0.1 0.0044 17.4 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Chi-conotoxin PF16981.5 KIK58085.1 - 0.015 15.6 0.1 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily FYRN PF05964.14 KIK58085.1 - 0.046 13.6 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 F/Y-rich N-terminus COesterase PF00135.28 KIK58088.1 - 1.2e-85 288.4 1.8 2.8e-84 283.8 1.8 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK58088.1 - 2.5e-10 40.6 0.7 1.6e-09 37.9 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK58089.1 - 4e-09 35.9 0.0 4.6e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KIK58090.1 - 1.5e-86 291.3 0.9 1.5e-85 288.1 0.9 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK58090.1 - 1.3e-10 41.5 0.6 6.8e-10 39.2 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK58090.1 - 0.32 9.8 0.5 0.79 8.5 0.1 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase FliC_SP PF12613.8 KIK58090.1 - 0.65 10.5 3.8 1.6 9.3 3.8 1.6 1 0 0 1 1 1 0 Flagellin structural protein COesterase PF00135.28 KIK58091.1 - 1.5e-88 298.0 0.1 1.9e-88 297.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK58091.1 - 1.3e-09 38.2 0.6 5.2e-09 36.3 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_16 PF00722.21 KIK58092.1 - 1.3e-17 63.8 1.4 1.5e-17 63.6 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Goodbye PF17109.5 KIK58093.1 - 6.3e-17 62.2 1.1 2.6e-16 60.1 0.0 2.6 3 0 0 3 3 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KIK58093.1 - 2.8e-11 43.6 0.0 6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58093.1 - 1e-06 29.2 0.0 3.3e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KIK58093.1 - 1.1e-05 25.5 0.2 8.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK58093.1 - 4.7e-05 23.7 0.2 0.00034 20.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK58093.1 - 0.00029 21.2 0.1 0.0016 18.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.14 KIK58093.1 - 0.0009 18.6 0.5 0.0031 16.8 0.1 2.1 2 0 0 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.27 KIK58093.1 - 0.0014 19.1 0.0 0.019 15.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter DUF2075 PF09848.9 KIK58093.1 - 0.0027 17.0 0.6 0.069 12.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KIK58093.1 - 0.0047 17.3 0.1 0.082 13.3 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK58093.1 - 0.0086 15.8 0.2 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain OmdA PF13376.6 KIK58093.1 - 0.011 15.7 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated NB-ARC PF00931.22 KIK58093.1 - 0.015 14.5 0.2 0.051 12.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 KIK58093.1 - 0.017 15.1 1.0 0.55 10.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KIK58093.1 - 0.038 14.5 1.6 1 9.9 0.1 3.4 3 1 0 3 3 2 0 AAA domain DUF1858 PF08984.11 KIK58093.1 - 0.074 13.2 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) DUF1906 PF08924.11 KIK58093.1 - 0.12 12.5 0.0 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) NAD_binding_6 PF08030.12 KIK58093.1 - 3.4 7.8 5.6 8.3 6.5 0.6 3.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain NPV_P10 PF05531.12 KIK58093.1 - 7.1 7.2 7.9 3.5 8.1 0.0 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2585 PF10755.9 KIK58097.1 - 0.049 13.4 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) RVT_1 PF00078.27 KIK58101.1 - 1.6e-08 34.4 0.0 1.8e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RF-1 PF00472.20 KIK58102.1 - 3.1e-21 75.5 0.8 4e-21 75.1 0.8 1.1 1 0 0 1 1 1 1 RF-1 domain PriX PF18689.1 KIK58102.1 - 0.013 15.9 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 Primase X Pox_G9-A16 PF03003.16 KIK58102.1 - 0.033 13.9 0.6 0.058 13.1 0.6 1.3 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 PHtD_u1 PF16645.5 KIK58102.1 - 0.86 10.1 3.9 5 7.6 3.9 2.2 1 1 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein NUC205 PF08168.11 KIK58104.1 - 0.08 12.5 0.4 0.2 11.2 0.4 1.6 1 0 0 1 1 1 0 NUC205 domain CAP_N PF01213.19 KIK58107.1 - 0.03 13.8 1.9 0.031 13.7 1.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Metal_resist PF13801.6 KIK58107.1 - 0.078 13.2 0.2 0.11 12.7 0.2 1.1 1 0 0 1 1 1 0 Heavy-metal resistance VIR_N PF15912.5 KIK58107.1 - 0.17 11.5 0.3 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Mito_fiss_reg PF05308.11 KIK58107.1 - 0.28 11.3 0.5 0.28 11.3 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Nsp1_C PF05064.13 KIK58108.1 - 0.0034 17.2 0.4 0.0056 16.5 0.4 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region YojJ PF10372.9 KIK58108.1 - 0.0084 16.2 1.6 0.034 14.2 0.1 2.3 1 1 1 2 2 2 1 Bacterial membrane-spanning protein N-terminus MscS_porin PF12795.7 KIK58108.1 - 0.023 14.3 5.2 0.034 13.7 5.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2730 PF10805.8 KIK58108.1 - 0.028 14.5 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 KIK58108.1 - 0.051 13.6 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 KIK58108.1 - 0.14 12.4 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Vps51 PF08700.11 KIK58108.1 - 0.14 12.3 1.0 0.28 11.3 1.0 1.6 1 1 0 1 1 1 0 Vps51/Vps67 SKA2 PF16740.5 KIK58108.1 - 0.33 10.8 2.7 7.7 6.3 1.4 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 KIK58108.1 - 1.3 9.6 7.5 4.6 7.8 4.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1996 PF09362.10 KIK58110.1 - 2.6e-74 250.2 2.3 2.6e-74 250.2 2.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) AAA_22 PF13401.6 KIK58111.1 - 0.018 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK58111.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KIK58114.1 - 0.083 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK58114.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 KIK58114.1 - 0.19 10.6 0.1 0.25 10.2 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain BofC_C PF08955.10 KIK58116.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 BofC C-terminal domain Helicase_C PF00271.31 KIK58118.1 - 1.3e-08 35.2 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box-like PF12937.7 KIK58120.1 - 0.023 14.6 0.0 0.083 12.8 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.6 KIK58120.1 - 0.058 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain HMw1_D2 PF18254.1 KIK58120.1 - 0.099 13.0 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 HMW1 domain 2 zf-C2HC5 PF06221.13 KIK58121.1 - 1.4e-15 57.0 6.4 2.1e-15 56.4 6.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type F-box-like PF12937.7 KIK58122.1 - 1.2e-09 37.9 0.2 2.2e-09 37.1 0.2 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK58122.1 - 0.5 10.3 3.0 2.1 8.3 3.0 1.9 1 1 0 1 1 1 0 F-box domain CHAT PF12770.7 KIK58124.1 - 1.7e-39 136.0 0.1 5.4e-39 134.3 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIK58124.1 - 1.5e-37 126.4 22.5 0.00098 18.9 0.1 13.3 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_11 PF13414.6 KIK58124.1 - 1.1e-14 53.8 4.7 0.14 11.9 0.0 10.9 13 0 0 13 13 13 3 TPR repeat TPR_8 PF13181.6 KIK58124.1 - 5.8e-14 51.1 0.3 1.1 9.7 0.0 11.2 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58124.1 - 3.7e-10 39.9 15.5 1.9 8.9 0.0 10.6 7 4 5 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58124.1 - 5.3e-09 35.5 3.2 1.3 9.3 0.0 9.3 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58124.1 - 3.5e-08 32.9 5.5 3.2 7.7 0.1 8.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK58124.1 - 5.8e-06 26.7 22.5 3.1 8.8 0.0 11.5 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58124.1 - 9.3e-05 22.2 2.8 77 3.7 0.0 7.7 8 1 0 8 8 7 0 Tetratricopeptide repeat CRISPR_Cse2 PF09485.10 KIK58124.1 - 0.0001 22.8 18.8 7.8 7.0 0.0 8.7 2 1 6 9 9 9 2 CRISPR-associated protein Cse2 (CRISPR_cse2) Surfac_D-trimer PF09006.11 KIK58124.1 - 0.0072 16.2 0.0 13 5.8 0.0 5.2 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation DUF4855 PF16147.5 KIK58124.1 - 0.013 14.6 0.1 7.5 5.5 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4855) DUF4326 PF14216.6 KIK58124.1 - 0.024 15.4 0.1 2e+02 2.8 0.0 5.9 4 2 2 6 6 6 0 Domain of unknown function (DUF4326) DUF4404 PF14357.6 KIK58124.1 - 0.13 12.9 8.2 83 3.9 0.0 6.2 6 2 2 8 8 6 0 Domain of unknown function (DUF4404) CorA PF01544.18 KIK58124.1 - 4.4 6.5 4.9 1.3 8.3 0.7 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GST_C PF00043.25 KIK58125.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KIK58125.1 - 0.79 9.7 6.1 0.64 10.0 2.2 3.0 3 1 0 3 3 3 0 F-box-like F-box-like PF12937.7 KIK58126.1 - 3.5e-08 33.2 0.1 1e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK58126.1 - 0.022 14.6 0.7 0.06 13.2 0.1 2.1 2 0 0 2 2 2 0 F-box domain Antimicrobial11 PF08106.11 KIK58126.1 - 2.2 8.5 10.2 7.2 6.8 4.6 2.6 2 0 0 2 2 2 0 Formaecin family R3H PF01424.22 KIK58127.1 - 5.5e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KIK58127.1 - 3.2e-07 30.3 32.6 2.1e-05 24.5 14.7 12.6 12 2 0 12 12 12 7 NF-X1 type zinc finger zf-NF-X1 PF01422.17 KIK58128.1 - 0.0029 17.6 25.4 0.01 15.9 6.6 10.3 12 0 0 12 12 12 4 NF-X1 type zinc finger Snapin_Pallidin PF14712.6 KIK58130.1 - 6.3e-06 26.5 0.9 0.053 13.9 0.6 2.4 2 0 0 2 2 2 2 Snapin/Pallidin Nsp1_C PF05064.13 KIK58130.1 - 3.9e-05 23.4 0.6 6.9e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 KIK58130.1 - 6.5e-05 23.0 15.8 6.5e-05 23.0 15.8 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KIK58130.1 - 0.0002 21.4 0.5 0.00043 20.3 0.3 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF1664) XhlA PF10779.9 KIK58130.1 - 0.00026 21.1 2.5 0.084 13.1 0.3 2.6 1 1 1 2 2 2 2 Haemolysin XhlA MscS_porin PF12795.7 KIK58130.1 - 0.00038 20.1 9.1 0.0011 18.6 9.2 1.6 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF2730 PF10805.8 KIK58130.1 - 0.002 18.2 1.0 0.021 14.9 1.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 KIK58130.1 - 0.0027 17.3 0.6 0.0032 17.1 0.6 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Vps51 PF08700.11 KIK58130.1 - 0.0036 17.3 0.3 0.008 16.2 0.3 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Tropomyosin_1 PF12718.7 KIK58130.1 - 0.0038 17.4 0.6 0.006 16.7 0.6 1.2 1 0 0 1 1 1 1 Tropomyosin like zf-ZPR1 PF03367.13 KIK58130.1 - 0.0049 16.7 2.8 0.18 11.6 0.9 2.9 1 1 2 3 3 3 1 ZPR1 zinc-finger domain Spc7 PF08317.11 KIK58130.1 - 0.0056 15.6 0.1 0.0079 15.1 0.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 KIK58130.1 - 0.012 15.8 0.0 0.7 10.2 0.0 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain HemX PF04375.14 KIK58130.1 - 0.014 14.7 0.6 0.023 14.0 0.6 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase COG5 PF10392.9 KIK58130.1 - 0.017 15.3 0.4 0.033 14.4 0.4 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Noelin-1 PF12308.8 KIK58130.1 - 0.023 14.6 0.7 0.075 13.0 0.5 2.0 1 1 0 1 1 1 0 Neurogenesis glycoprotein DUF3450 PF11932.8 KIK58130.1 - 0.024 14.0 0.2 0.037 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tropomyosin PF00261.20 KIK58130.1 - 0.025 14.0 0.5 0.038 13.4 0.5 1.2 1 0 0 1 1 1 0 Tropomyosin NPV_P10 PF05531.12 KIK58130.1 - 0.025 15.0 5.6 0.19 12.2 4.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4349 PF14257.6 KIK58130.1 - 0.025 14.0 0.6 0.037 13.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Prefoldin_2 PF01920.20 KIK58130.1 - 0.031 14.2 0.3 0.23 11.4 0.0 2.4 1 1 1 2 2 2 0 Prefoldin subunit CLZ PF16526.5 KIK58130.1 - 0.037 14.4 1.0 0.25 11.7 0.3 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Filament PF00038.21 KIK58130.1 - 0.044 13.4 0.6 0.064 12.8 0.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein Vac_Fusion PF02346.16 KIK58130.1 - 0.044 13.4 0.5 5.5 6.7 0.0 2.6 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 EzrA PF06160.12 KIK58130.1 - 0.045 11.9 0.2 0.057 11.6 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Myosin_tail_1 PF01576.19 KIK58130.1 - 0.051 11.4 0.2 0.066 11.0 0.2 1.0 1 0 0 1 1 1 0 Myosin tail DUF745 PF05335.13 KIK58130.1 - 0.068 12.9 0.3 0.17 11.6 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Sec2p PF06428.11 KIK58130.1 - 0.07 13.1 4.0 0.38 10.7 1.5 2.5 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 KIK58130.1 - 0.081 12.9 2.1 0.34 10.9 1.3 2.0 1 1 0 1 1 1 0 Laminin Domain II YojJ PF10372.9 KIK58130.1 - 0.087 12.9 0.1 4.7 7.4 0.0 2.8 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF16 PF01519.16 KIK58130.1 - 0.11 13.1 2.8 0.21 12.1 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 BST2 PF16716.5 KIK58130.1 - 0.15 12.7 2.9 0.15 12.7 1.5 1.7 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 KIK58130.1 - 0.16 12.0 1.6 0.22 11.5 0.9 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding DHR10 PF18595.1 KIK58130.1 - 0.16 12.1 1.8 0.32 11.1 1.3 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Sugarporin_N PF11471.8 KIK58130.1 - 0.16 11.9 0.1 6 6.9 0.0 2.5 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension FPP PF05911.11 KIK58130.1 - 0.17 10.1 0.1 0.18 9.9 0.1 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 KIK58130.1 - 0.25 11.8 2.9 2.2 8.8 0.4 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 KIK58130.1 - 0.25 11.5 5.4 0.6 10.3 5.4 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF948 PF06103.11 KIK58130.1 - 7.9 6.8 8.1 28 5.0 4.7 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MMU163 PF17119.5 KIK58131.1 - 0.036 13.2 0.3 0.051 12.7 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Goodbye PF17109.5 KIK58133.1 - 4.1e-10 40.2 0.0 5.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Goodbye PF17109.5 KIK58135.1 - 4.3e-20 72.4 0.2 1.5e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain DUF1906 PF08924.11 KIK58135.1 - 0.0066 16.6 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1906) NPV_P10 PF05531.12 KIK58135.1 - 0.028 14.9 0.6 8.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IgaA PF07095.11 KIK58138.1 - 0.049 11.6 0.6 0.07 11.1 0.6 1.2 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA YTH PF04146.15 KIK58140.1 - 8.7e-40 136.4 0.0 2.7e-39 134.8 0.0 1.9 1 0 0 1 1 1 1 YT521-B-like domain HSP70 PF00012.20 KIK58141.1 - 0.0014 16.9 0.1 0.0037 15.5 0.1 1.6 1 1 0 1 1 1 1 Hsp70 protein Tropomyosin_1 PF12718.7 KIK58142.1 - 0.017 15.3 4.4 0.028 14.6 4.4 1.2 1 0 0 1 1 1 0 Tropomyosin like ADIP PF11559.8 KIK58142.1 - 0.024 14.7 2.3 0.46 10.6 5.2 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KIK58142.1 - 0.026 13.8 2.5 0.041 13.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 KIK58142.1 - 0.12 13.1 0.7 0.24 12.1 0.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KIK58142.1 - 0.17 11.7 4.3 0.34 10.7 4.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Zn_clus PF00172.18 KIK58143.1 - 0.014 15.5 1.5 0.029 14.5 1.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin_1 PF12718.7 KIK58144.1 - 0.0065 16.6 1.6 0.014 15.6 1.6 1.4 1 0 0 1 1 1 1 Tropomyosin like DivIC PF04977.15 KIK58144.1 - 0.38 10.6 7.0 0.96 9.3 6.4 1.9 2 0 0 2 2 2 0 Septum formation initiator JAKMIP_CC3 PF16034.5 KIK58144.1 - 1.4 8.8 5.5 3.2 7.6 3.8 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain FlaC_arch PF05377.11 KIK58144.1 - 1.9 8.9 4.9 1.5 9.2 2.7 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ATP_bind_3 PF01171.20 KIK58145.1 - 2e-39 135.2 0.0 3e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family TPR_10 PF13374.6 KIK58146.1 - 6.8e-54 178.4 1.1 7.3e-10 38.4 0.0 7.9 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58146.1 - 9.1e-53 176.5 11.1 4.2e-11 43.0 0.0 6.0 3 2 4 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58146.1 - 1.6e-15 56.2 5.8 0.45 10.4 0.1 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58146.1 - 8e-15 53.7 3.6 0.4 11.0 0.0 6.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58146.1 - 3.1e-14 51.9 13.5 0.15 12.1 0.0 6.7 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58146.1 - 1.8e-12 46.3 5.7 2 8.7 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58146.1 - 1.8e-10 40.4 6.9 1.5 9.3 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58146.1 - 3.3e-08 33.4 0.0 6.5 7.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 KIK58146.1 - 5.5e-08 32.8 0.1 21 5.3 0.0 6.3 4 2 3 7 7 6 0 Rapsyn N-terminal myristoylation and linker region Phage_term_smal PF05944.12 KIK58146.1 - 9e-08 32.2 0.0 10 6.1 0.0 5.9 3 1 3 6 6 6 0 Phage small terminase subunit ANAPC3 PF12895.7 KIK58146.1 - 1.4e-07 31.7 0.0 0.052 13.8 0.0 3.8 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KIK58146.1 - 6e-07 29.6 0.0 1.1 9.3 0.0 4.3 1 1 3 4 4 4 4 Domain of Unknown Function (DUF3856) PPR PF01535.20 KIK58146.1 - 7.1e-07 29.1 3.1 47 4.5 0.0 6.8 7 0 0 7 7 7 0 PPR repeat Type_III_YscG PF09477.10 KIK58146.1 - 1.1e-06 28.7 0.3 0.24 11.5 0.0 4.5 3 2 1 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_19 PF14559.6 KIK58146.1 - 1.6e-06 28.5 0.6 0.53 10.8 0.0 4.4 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_5 PF12688.7 KIK58146.1 - 4.1e-06 27.0 0.1 2 8.6 0.0 3.9 1 1 2 3 3 3 2 Tetratrico peptide repeat DUF3400 PF11880.8 KIK58146.1 - 7.8e-06 25.3 0.1 7.6 6.2 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3400) TPR_16 PF13432.6 KIK58146.1 - 8.6e-06 26.3 0.3 1e+02 3.7 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat YqaH PF17448.2 KIK58146.1 - 1.7e-05 25.1 0.0 6.4 7.2 0.0 4.8 2 2 3 5 5 5 0 Uncharacterized YqaH-like TPR_20 PF14561.6 KIK58146.1 - 2.4e-05 24.6 0.8 41 4.6 0.0 5.2 2 2 3 5 5 5 0 Tetratricopeptide repeat SPOB_a PF14689.6 KIK58146.1 - 7.4e-05 22.4 4.5 32 4.3 0.0 6.1 7 0 0 7 7 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain Wzy_C_2 PF11846.8 KIK58146.1 - 0.0013 18.7 2.4 58 3.5 0.0 5.5 5 1 1 7 7 6 0 Virulence factor membrane-bound polymerase, C-terminal DUF4866 PF16160.5 KIK58146.1 - 0.0031 16.9 0.4 0.55 9.5 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4866) TPR_6 PF13174.6 KIK58146.1 - 0.0041 17.7 1.3 1.8e+02 3.1 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat MCPVI PF02993.14 KIK58146.1 - 0.005 16.7 0.6 7.4 6.3 0.0 3.5 1 1 2 4 4 4 0 Minor capsid protein VI TPR_3 PF07720.12 KIK58146.1 - 0.011 15.7 1.0 1.5e+02 2.5 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58146.1 - 0.012 15.0 1.1 0.62 9.4 0.1 3.3 1 1 2 3 3 3 0 MalT-like TPR region R-HINP1I PF11463.8 KIK58146.1 - 0.026 14.0 0.0 26 4.2 0.0 3.9 3 1 2 5 5 5 0 R.HinP1I restriction endonuclease ACP_PD PF04336.12 KIK58146.1 - 0.077 13.4 1.2 11 6.5 0.0 3.7 1 1 4 5 5 5 0 Acyl carrier protein phosphodiesterase NB-ARC PF00931.22 KIK58147.1 - 6e-05 22.3 0.2 0.00045 19.5 0.2 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK58147.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK58147.1 - 0.0074 16.6 0.0 0.044 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KIK58147.1 - 0.01 15.4 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KIK58147.1 - 0.016 15.2 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 KIK58147.1 - 0.079 12.9 0.1 0.16 11.9 0.1 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Abhydrolase_1 PF00561.20 KIK58148.1 - 5e-05 23.1 0.0 0.0061 16.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK58148.1 - 0.00013 22.7 0.0 0.00016 22.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK58148.1 - 0.00021 20.7 0.0 0.0017 17.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KIK58148.1 - 0.013 15.2 0.1 0.078 12.6 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KIK58148.1 - 0.013 15.0 0.0 0.065 12.7 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIK58148.1 - 0.015 15.1 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 KIK58148.1 - 0.078 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Phage_Coat_A PF05357.13 KIK58148.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage Coat Protein A Abhydrolase_5 PF12695.7 KIK58148.1 - 0.15 11.8 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.11 KIK58148.1 - 0.2 10.9 0.0 6 6.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KIK58149.1 - 6.1e-12 46.6 1.0 7.5e-12 46.3 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK58149.1 - 4.4e-11 42.9 0.0 8.9e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK58149.1 - 1e-09 38.0 0.0 1.8e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIK58149.1 - 0.001 18.9 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KIK58149.1 - 0.012 15.3 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S9 PF00326.21 KIK58149.1 - 0.034 13.6 0.0 6.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 KIK58149.1 - 0.2 11.3 0.0 0.81 9.3 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) SRP40_C PF05022.12 KIK58150.1 - 4.4e-26 91.5 2.7 4.4e-26 91.5 2.7 2.9 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.11 KIK58150.1 - 0.046 13.7 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 LisH UB2H PF14814.6 KIK58150.1 - 0.15 12.1 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain DMRL_synthase PF00885.19 KIK58151.1 - 1.9e-57 193.1 0.0 2.4e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Gtr1_RagA PF04670.12 KIK58152.1 - 2.1e-87 292.3 0.0 3.1e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK58152.1 - 3.9e-08 33.5 0.0 8.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK58152.1 - 4.8e-07 29.4 0.0 8.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KIK58152.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KIK58152.1 - 4.1e-06 26.9 0.0 7.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIK58152.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIK58152.1 - 0.14 11.9 0.1 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KIK58152.1 - 0.14 12.0 0.2 4.8 7.1 0.1 2.6 3 0 0 3 3 3 0 RsgA GTPase SR-25 PF10500.9 KIK58152.1 - 0.62 9.6 10.9 1.1 8.8 10.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 KIK58152.1 - 0.78 9.4 8.3 1.1 8.9 8.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 BRCT_2 PF16589.5 KIK58153.1 - 4.1e-05 23.9 0.0 0.00029 21.2 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIK58153.1 - 4.1e-05 23.7 0.7 0.00019 21.6 0.7 2.1 1 1 0 1 1 1 1 Rap1 Myb domain PGA2 PF07543.12 KIK58153.1 - 4.6 7.2 17.3 3.7 7.5 4.5 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 Lin-8 PF03353.15 KIK58153.1 - 9.6 5.7 15.6 0.43 10.1 4.5 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MFS_1 PF07690.16 KIK58154.1 - 7.9e-23 80.9 22.0 5.2e-18 65.1 5.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK58154.1 - 1.3e-06 27.6 1.3 1.3e-06 27.6 1.3 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KIK58154.1 - 0.00044 18.7 1.3 0.012 14.0 0.8 2.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 KIK58154.1 - 0.013 13.8 0.1 0.013 13.8 0.1 2.1 2 1 0 2 2 2 0 BT1 family Pkinase PF00069.25 KIK58156.1 - 1.3e-40 139.5 0.0 1.7e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK58156.1 - 1.7e-15 57.0 0.0 4.8e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK58156.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like BTB PF00651.31 KIK58157.1 - 0.024 14.8 0.0 0.72 10.1 0.0 2.3 3 0 0 3 3 3 0 BTB/POZ domain GDA1_CD39 PF01150.17 KIK58158.1 - 8.5e-100 334.4 0.0 4e-99 332.2 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KIK58158.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family WSK PF03832.13 KIK58158.1 - 0.48 10.1 3.0 1 9.1 3.0 1.5 1 0 0 1 1 1 0 WSK motif Atg14 PF10186.9 KIK58159.1 - 0.0027 16.8 9.6 0.0041 16.3 9.6 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KIK58159.1 - 0.045 14.0 16.3 0.095 12.9 16.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KIK58159.1 - 0.12 12.4 13.1 0.26 11.4 13.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nsp1_C PF05064.13 KIK58159.1 - 0.25 11.2 6.3 0.19 11.5 3.9 2.1 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF4407 PF14362.6 KIK58159.1 - 0.57 9.5 8.8 0.98 8.7 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KIK58159.1 - 1.2 8.6 12.0 1.1 8.8 10.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 KIK58159.1 - 1.2 9.2 15.9 0.66 10.1 7.8 2.6 1 1 1 2 2 2 0 Tropomyosin like Dynamin_M PF01031.20 KIK58161.1 - 4.1e-29 101.7 0.4 1.4e-28 99.9 0.4 1.8 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK58161.1 - 1.8e-27 96.5 0.0 6.2e-27 94.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KIK58161.1 - 9.8e-12 44.9 0.4 9.5e-11 41.7 0.5 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK58161.1 - 7.4e-06 26.0 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK58161.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK58161.1 - 0.029 14.7 1.6 0.07 13.5 0.0 2.5 3 1 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 KIK58161.1 - 0.069 13.4 0.0 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KIK58161.1 - 0.39 10.4 2.0 0.82 9.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_M PF01031.20 KIK58162.1 - 3.4e-29 102.0 0.0 6.6e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK58162.1 - 5e-27 95.0 0.0 1.7e-26 93.3 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KIK58162.1 - 1.7e-07 31.3 0.0 6.6e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK58162.1 - 0.00052 20.1 0.2 0.0058 16.7 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ribosomal_S26e PF01283.19 KIK58165.1 - 5.1e-52 174.9 10.6 5.9e-52 174.7 10.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KIK58165.1 - 0.0065 16.4 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc binding domain Fer4_7 PF12838.7 KIK58165.1 - 0.029 14.9 1.4 0.8 10.3 0.4 2.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ifi-6-16 PF06140.13 KIK58167.1 - 0.0071 16.2 30.5 0.083 12.8 30.5 2.3 1 1 0 1 1 1 1 Interferon-induced 6-16 family F-box-like PF12937.7 KIK58167.1 - 0.011 15.6 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 F-box-like SF3A3 PF16837.5 KIK58167.1 - 0.032 14.7 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Aldo_ket_red PF00248.21 KIK58169.1 - 5.5e-51 173.5 0.0 6.3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexokinase_1 PF00349.21 KIK58169.1 - 0.057 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Hexokinase zf-BED PF02892.15 KIK58171.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger BUD22 PF09073.10 KIK58172.1 - 1.1 8.5 8.0 1.6 8.0 8.0 1.2 1 0 0 1 1 1 0 BUD22 Lipase_GDSL_2 PF13472.6 KIK58173.1 - 1.2e-28 100.7 0.0 1.8e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK58173.1 - 9.4e-17 61.6 0.0 1.3e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Caskin-Pro-rich PF16907.5 KIK58175.1 - 0.27 11.8 3.4 0.51 10.9 3.4 1.4 1 0 0 1 1 1 0 Proline rich region of Caskin proteins SDA1 PF05285.12 KIK58176.1 - 2.3 7.6 7.6 2.9 7.2 7.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIK58176.1 - 6 6.1 11.5 8.1 5.7 11.5 1.1 1 0 0 1 1 1 0 BUD22 VPS28 PF03997.12 KIK58178.1 - 2.6e-70 236.0 0.0 3e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Sensor_TM1 PF13755.6 KIK58179.1 - 0.2 11.4 1.4 0.37 10.5 1.4 1.4 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF1275 PF06912.11 KIK58181.1 - 7.7e-30 104.3 9.2 9.6e-30 103.9 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KIK58181.1 - 0.84 8.5 18.3 0.019 13.9 1.7 2.7 2 1 0 3 3 3 0 Major Facilitator Superfamily F-box-like PF12937.7 KIK58182.1 - 0.016 15.1 0.3 0.049 13.5 0.3 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KIK58182.1 - 0.031 14.7 0.2 50 4.5 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Rep_fac-A_C PF08646.10 KIK58183.1 - 7.5e-51 171.7 2.5 2.9e-47 160.1 0.2 2.8 4 0 0 4 4 4 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KIK58183.1 - 3.8e-35 119.7 0.6 2.1e-34 117.4 0.1 2.4 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KIK58183.1 - 3.6e-19 68.7 0.0 8.9e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KIK58183.1 - 4.6e-14 52.2 0.4 1.3e-12 47.5 0.0 3.1 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KIK58183.1 - 0.00063 17.7 0.1 0.019 12.9 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5521) DUF4799 PF16056.5 KIK58183.1 - 0.019 14.1 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) DUF4539 PF15072.6 KIK58183.1 - 0.02 14.9 0.0 0.098 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) zinc-ribbons_6 PF07191.12 KIK58183.1 - 0.13 12.3 0.9 0.24 11.4 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbons Aldo_ket_red PF00248.21 KIK58186.1 - 1.1e-50 172.5 0.0 1.3e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SKG6 PF08693.10 KIK58187.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 KIK58187.1 - 0.034 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity LapA_dom PF06305.11 KIK58187.1 - 0.051 13.4 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain p450 PF00067.22 KIK58188.1 - 5.9e-47 160.5 0.0 8e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KIK58189.1 - 3e-20 72.4 4.5 5.1e-20 71.6 4.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK58189.1 - 0.0003 20.9 12.1 0.0003 20.9 12.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_US12 PF05363.12 KIK58189.1 - 0.027 15.2 0.8 16 6.3 0.1 3.4 3 0 0 3 3 3 0 Herpesvirus US12 family DUF4094 PF13334.6 KIK58189.1 - 0.05 14.0 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF1192 PF06698.11 KIK58189.1 - 0.32 11.1 2.5 3.2 7.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 KIK58189.1 - 0.36 11.1 1.4 0.91 9.8 1.4 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain IDO PF01231.18 KIK58190.1 - 1.5e-120 402.9 0.0 1.7e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ECH_2 PF16113.5 KIK58191.1 - 1.9e-110 369.5 0.0 2.3e-110 369.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KIK58191.1 - 3e-23 82.4 0.0 1.4e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase FliG_N PF14842.6 KIK58191.1 - 0.13 12.8 0.0 0.53 10.9 0.0 2.0 2 0 0 2 2 2 0 FliG N-terminal domain CAP_GLY PF01302.25 KIK58192.1 - 1e-19 70.3 0.2 2.3e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 KIK58192.1 - 1.3e-10 41.1 0.0 5e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KIK58192.1 - 1.8e-07 30.8 16.5 0.0055 16.4 7.4 5.0 4 2 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KIK58192.1 - 5e-05 23.6 23.0 0.12 12.8 8.3 5.6 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 KIK58194.1 - 7.4e-26 89.8 0.1 2.4e-13 49.7 0.3 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK58194.1 - 0.0026 17.8 0.0 0.083 13.0 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIK58194.1 - 0.0043 17.0 0.0 0.29 11.1 0.0 2.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KIK58194.1 - 0.034 14.1 0.1 2 8.5 0.0 2.8 3 1 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.8 KIK58194.1 - 0.056 13.5 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 Aminotran_5 PF00266.19 KIK58195.1 - 5.2e-92 308.6 0.0 6.2e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK58195.1 - 7.1e-07 28.8 0.1 9.9e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KIK58195.1 - 0.00012 21.5 0.1 0.00026 20.4 0.2 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIK58195.1 - 0.0073 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme p450 PF00067.22 KIK58196.1 - 6e-42 144.0 0.0 8.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_6 PF01341.17 KIK58197.1 - 2.3e-103 346.1 0.1 3e-103 345.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KIK58197.1 - 1.3e-14 53.8 10.1 3.4e-14 52.5 10.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1681 PF07933.14 KIK58198.1 - 2.7e-54 182.9 0.0 3.2e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CSN8_PSD8_EIF3K PF10075.9 KIK58199.1 - 5.4e-14 52.4 0.0 7.5e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 KIK58199.1 - 0.058 13.9 0.0 0.21 12.1 0.0 1.8 1 1 1 2 2 2 0 PCI domain PPR_long PF17177.4 KIK58199.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP NIF PF03031.18 KIK58200.1 - 4.2e-19 68.8 0.0 6.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KIK58200.1 - 7.1e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family NUDIX PF00293.28 KIK58202.1 - 8.6e-10 38.8 0.0 2e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIK58202.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain CheC PF04509.12 KIK58202.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 CheC-like family F-box-like PF12937.7 KIK58204.1 - 6.1e-08 32.4 0.1 6.1e-08 32.4 0.1 2.5 3 0 0 3 3 3 1 F-box-like Vps52 PF04129.12 KIK58204.1 - 0.096 11.4 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family EF-hand_4 PF12763.7 KIK58205.1 - 0.048 13.6 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand CwfJ_C_2 PF04676.14 KIK58206.1 - 4e-34 117.5 0.0 1.6e-33 115.5 0.0 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KIK58206.1 - 2.8e-26 91.8 0.0 4.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 WD40 PF00400.32 KIK58209.1 - 7.7e-105 339.9 56.8 1.2e-09 38.6 0.5 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58209.1 - 4.7e-42 142.2 7.7 0.011 16.1 0.0 12.5 1 1 12 13 13 13 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58209.1 - 2.2e-15 56.5 11.2 0.048 12.6 0.1 9.9 6 4 5 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK58209.1 - 1.2e-13 50.2 0.0 0.12 10.7 0.0 7.9 5 1 2 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK58209.1 - 6.3e-11 42.1 0.0 0.14 11.5 0.0 5.2 4 2 2 6 6 6 3 WD40-like domain PD40 PF07676.12 KIK58209.1 - 2.9e-10 39.8 10.0 6.6 6.8 0.0 9.7 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK58209.1 - 1.4e-08 34.6 12.2 0.0027 17.3 0.6 3.9 1 1 0 3 3 3 3 PQQ-like domain Cuticle_4 PF15955.5 KIK58209.1 - 2.6e-07 31.2 0.0 6.1 7.6 0.0 6.6 9 0 0 9 9 7 1 Cuticle protein PQQ PF01011.21 KIK58209.1 - 3.4e-07 29.9 0.1 23 5.1 0.0 8.7 10 0 0 10 10 10 0 PQQ enzyme repeat Nup160 PF11715.8 KIK58209.1 - 4.8e-07 28.8 4.3 4.4 5.8 0.0 7.5 4 3 3 9 9 9 2 Nucleoporin Nup120/160 FCP1_C PF09309.10 KIK58209.1 - 0.0028 17.6 0.0 22 4.8 0.0 5.2 4 2 3 7 7 7 0 FCP1, C-terminal DUF1854 PF08909.11 KIK58209.1 - 0.0053 16.6 0.1 0.071 12.9 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1854) Coatomer_WDAD PF04053.14 KIK58209.1 - 0.078 12.0 0.2 0.83 8.6 0.0 2.6 2 1 0 2 2 2 0 Coatomer WD associated region Me-amine-dh_H PF06433.11 KIK58209.1 - 0.089 11.6 0.0 32 3.3 0.0 4.0 4 3 1 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) DCX PF03607.17 KIK58209.1 - 0.13 12.3 0.0 1.1e+02 3.0 0.0 4.6 7 0 0 7 7 6 0 Doublecortin Nbas_N PF15492.6 KIK58209.1 - 1.3 8.3 5.5 12 5.1 0.0 4.4 3 3 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 KIK58209.1 - 2.8 7.7 17.8 50 3.7 0.0 8.1 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KIK58210.1 - 0.00015 22.2 0.0 0.00018 22.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KIK58210.1 - 0.0019 18.1 0.1 0.0031 17.4 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.12 KIK58210.1 - 0.0025 17.8 0.0 0.004 17.1 0.0 1.4 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK58210.1 - 0.0048 17.3 0.2 0.0077 16.6 0.2 1.6 1 1 0 1 1 1 1 RNA helicase PIF1 PF05970.14 KIK58210.1 - 0.008 15.4 0.2 0.013 14.7 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_7 PF12775.7 KIK58210.1 - 0.0085 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 KIK58210.1 - 0.0086 16.6 0.2 0.012 16.1 0.2 1.4 1 1 0 1 1 1 1 ABC transporter TsaE PF02367.17 KIK58210.1 - 0.0099 15.9 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KIK58210.1 - 0.017 14.2 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KIK58210.1 - 0.017 15.0 0.1 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 KIK58210.1 - 0.028 14.8 0.1 0.061 13.8 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK58210.1 - 0.028 14.7 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK58210.1 - 0.033 13.9 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KIK58210.1 - 0.039 13.2 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KIK58210.1 - 0.043 14.0 0.2 0.066 13.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK58210.1 - 0.048 13.4 0.1 0.048 13.4 0.1 1.2 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK58210.1 - 0.049 13.7 0.3 0.091 12.8 0.3 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 KIK58210.1 - 0.065 13.1 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KIK58210.1 - 0.097 12.4 0.3 0.12 12.1 0.3 1.3 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 KIK58210.1 - 0.1 12.7 0.3 0.67 10.0 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIK58210.1 - 0.14 12.2 0.2 0.2 11.8 0.2 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Parvo_NS1 PF01057.17 KIK58210.1 - 0.15 11.1 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KIK58210.1 - 0.17 12.4 1.5 0.25 11.8 1.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK58210.1 - 0.19 12.3 0.7 0.26 11.8 0.7 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK58212.1 - 1.7e-06 28.0 0.0 2.5e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58212.1 - 0.0001 22.7 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIK58212.1 - 0.00036 20.7 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK58212.1 - 0.00051 20.5 0.1 0.0011 19.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK58212.1 - 0.00068 18.9 0.0 0.0015 17.8 0.0 1.4 1 1 0 2 2 2 1 NB-ARC domain PIF1 PF05970.14 KIK58212.1 - 0.00087 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.27 KIK58212.1 - 0.0019 18.7 0.0 0.0025 18.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 KIK58212.1 - 0.0031 17.9 0.2 0.0041 17.5 0.2 1.6 1 1 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KIK58212.1 - 0.0037 17.0 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK58212.1 - 0.0042 17.0 0.0 0.0067 16.4 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KIK58212.1 - 0.0054 16.6 0.1 0.0089 15.9 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_7 PF12775.7 KIK58212.1 - 0.0058 16.2 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KIK58212.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK58212.1 - 0.036 14.1 0.1 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIK58212.1 - 0.059 13.9 0.4 0.079 13.5 0.4 1.5 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK58212.1 - 0.068 12.9 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase PhoH PF02562.16 KIK58212.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 KIK58212.1 - 0.089 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KIK58212.1 - 0.091 12.7 0.1 0.097 12.6 0.1 1.4 1 1 0 1 1 1 0 NTPase DUF815 PF05673.13 KIK58212.1 - 0.091 11.9 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SRP54 PF00448.22 KIK58212.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KIK58212.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase 6PF2K PF01591.18 KIK58212.1 - 0.13 11.5 0.1 0.22 10.8 0.1 1.3 1 1 0 1 1 1 0 6-phosphofructo-2-kinase TniB PF05621.11 KIK58212.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KIK58212.1 - 0.16 11.7 0.3 0.15 11.7 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK58212.1 - 0.2 11.2 0.2 0.39 10.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK58212.1 - 0.21 10.8 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 KIK58212.1 - 0.22 11.6 0.5 0.56 10.3 0.3 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain CbiA PF01656.23 KIK58212.1 - 0.25 11.4 0.5 0.54 10.3 0.5 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 KIK58213.1 - 1.8e-108 351.3 47.4 8.7e-10 39.0 0.1 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58213.1 - 4.2e-41 139.2 4.6 0.00054 20.2 0.1 11.6 1 1 9 12 12 12 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58213.1 - 4.5e-17 62.0 5.9 0.078 11.9 0.0 8.4 4 3 3 8 8 8 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK58213.1 - 2.5e-15 55.8 0.0 0.038 12.3 0.0 7.2 4 2 4 8 8 8 6 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK58213.1 - 4.5e-11 42.4 13.1 4.8 7.3 0.0 10.1 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK58213.1 - 1.3e-09 38.2 0.0 0.033 14.1 0.0 4.1 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK58213.1 - 8.5e-08 31.9 0.0 0.14 11.4 0.0 5.3 1 1 5 7 7 7 3 WD40-like domain CHAP PF05257.16 KIK58213.1 - 1.7e-07 31.7 15.5 2.6 8.7 0.5 8.7 1 1 6 8 8 8 1 CHAP domain Gmad1 PF10647.9 KIK58213.1 - 2.3e-07 30.8 6.7 0.082 12.6 0.7 7.3 2 2 4 6 6 6 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK58213.1 - 9.7e-06 24.5 0.3 0.71 8.4 0.1 6.1 4 2 4 9 9 9 1 Nucleoporin Nup120/160 Cuticle_4 PF15955.5 KIK58213.1 - 1.3e-05 25.8 0.5 95 3.8 0.0 7.0 8 0 0 8 8 8 0 Cuticle protein PQQ PF01011.21 KIK58213.1 - 2.2e-05 24.1 0.3 7.5 6.7 0.0 7.0 8 0 0 8 8 8 1 PQQ enzyme repeat PQQ_2 PF13360.6 KIK58213.1 - 6.5e-05 22.6 9.1 0.19 11.2 0.9 4.0 2 2 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 KIK58213.1 - 0.00011 22.6 5.0 1.6 9.3 0.0 7.0 6 3 2 8 8 8 1 PQQ-like domain Ret2_MD PF18528.1 KIK58213.1 - 0.0012 19.2 0.2 36 4.8 0.0 5.5 3 1 2 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nucleoporin_N PF08801.11 KIK58213.1 - 0.0036 16.1 6.3 13 4.4 0.0 6.1 3 2 3 6 6 6 0 Nup133 N terminal like Peptidase_S9_N PF02897.15 KIK58213.1 - 0.0049 15.7 0.1 15 4.2 0.0 4.9 2 1 3 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 KIK58213.1 - 0.036 13.8 16.1 47 3.8 0.0 8.3 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature WD40_3 PF15911.5 KIK58213.1 - 0.16 12.0 0.6 2.6e+02 1.7 0.0 4.8 5 0 0 5 5 4 0 WD domain, G-beta repeat DUF374 PF04028.13 KIK58213.1 - 1.3 8.6 4.9 17 5.1 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF374) DNA_pol_phi PF04931.13 KIK58215.1 - 9.3 4.2 5.2 15 3.5 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi HMGL-like PF00682.19 KIK58216.1 - 8.9e-70 235.2 0.0 1.6e-69 234.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIK58216.1 - 1.5e-42 144.7 0.0 4e-21 75.3 0.0 2.5 2 1 0 2 2 2 2 LeuA allosteric (dimerisation) domain HU-CCDC81_euk_2 PF18289.1 KIK58216.1 - 0.046 13.9 0.0 14 6.0 0.0 3.5 3 0 0 3 3 3 0 CCDC81 eukaryotic HU domain 2 p450 PF00067.22 KIK58217.1 - 2.9e-31 108.7 0.0 3.9e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PDDEXK_1 PF12705.7 KIK58217.1 - 0.01 15.8 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Baculo_PEP_C PF04513.12 KIK58218.1 - 0.00032 20.8 13.0 0.0016 18.5 7.7 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Peripla_BP_2 PF01497.18 KIK58218.1 - 0.0041 16.7 0.0 0.005 16.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Ran-binding PF05508.11 KIK58218.1 - 0.024 13.6 0.1 0.033 13.2 0.1 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Rac1 PF09632.10 KIK58218.1 - 0.046 12.9 0.3 0.046 12.9 0.3 1.5 2 0 0 2 2 2 0 Rac1-binding domain RPW8 PF05659.11 KIK58218.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NPV_P10 PF05531.12 KIK58218.1 - 1.1 9.8 4.9 2.2 8.8 4.0 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein F-box-like PF12937.7 KIK58221.1 - 4.9e-10 39.2 1.4 9.3e-10 38.3 1.4 1.5 1 0 0 1 1 1 1 F-box-like SAS4 PF15460.6 KIK58221.1 - 0.028 14.5 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 F-box PF00646.33 KIK58221.1 - 0.061 13.2 0.4 0.061 13.2 0.4 2.6 3 1 0 3 3 3 0 F-box domain Vps52 PF04129.12 KIK58221.1 - 0.065 12.0 0.1 0.078 11.7 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family Aspzincin_M35 PF14521.6 KIK58221.1 - 0.15 12.6 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase F-box-like PF12937.7 KIK58222.1 - 6.5e-10 38.7 0.7 1.8e-09 37.3 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK58222.1 - 0.05 13.5 0.9 0.39 10.7 0.7 2.4 2 1 0 2 2 2 0 F-box domain Attacin_N PF03768.15 KIK58223.1 - 0.11 12.7 0.8 0.11 12.7 0.8 2.5 2 0 0 2 2 2 0 Attacin, N-terminal region Transformer PF06495.11 KIK58224.1 - 0.0011 19.2 19.0 0.0015 18.7 19.0 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein DUF4614 PF15391.6 KIK58224.1 - 0.031 14.3 1.6 0.037 14.0 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) ORC6 PF05460.13 KIK58224.1 - 0.28 10.4 3.1 0.27 10.4 3.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.14 KIK58224.1 - 0.43 8.8 1.5 0.48 8.6 1.5 1.0 1 0 0 1 1 1 0 CDC45-like protein KAR9 PF08580.10 KIK58224.1 - 1 7.8 5.9 1.2 7.5 5.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 tRNA-synt_1c PF00749.21 KIK58225.1 - 5.6e-111 370.4 0.0 7.6e-111 370.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KIK58225.1 - 2.9e-39 134.7 0.2 5.2e-39 133.9 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 KIK58225.1 - 0.00015 22.0 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK58225.1 - 0.00073 19.5 0.1 0.0018 18.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KIK58225.1 - 0.0012 18.3 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.6 KIK58225.1 - 0.017 15.3 0.0 0.06 13.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MCM PF00493.23 KIK58229.1 - 4.4e-106 353.0 0.0 8.4e-106 352.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK58229.1 - 9.1e-29 99.9 0.3 1.7e-28 99.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK58229.1 - 3.7e-22 78.5 1.9 9e-22 77.3 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK58229.1 - 2.5e-20 73.0 2.1 6.6e-20 71.6 2.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KIK58229.1 - 4.4e-09 36.5 0.1 6.8e-07 29.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIK58229.1 - 3.9e-08 32.9 0.1 1.1e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 KIK58229.1 - 1.6e-05 25.4 1.5 4.2e-05 24.1 0.6 2.2 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KIK58229.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIK58229.1 - 0.015 15.2 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 KIK58229.1 - 0.03 14.0 0.0 0.85 9.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain TBCC_N PF16752.5 KIK58229.1 - 0.14 12.6 2.5 0.12 12.9 0.4 2.0 2 0 0 2 2 1 0 Tubulin-specific chaperone C N-terminal domain DNA_methylase PF00145.17 KIK58230.1 - 1.8e-57 195.2 0.0 6.3e-57 193.4 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIK58230.1 - 6.7e-17 61.5 0.6 1.2e-11 44.6 0.1 2.6 2 0 0 2 2 2 2 BAH domain Cons_hypoth95 PF03602.15 KIK58230.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RHSP PF07999.11 KIK58232.1 - 0.00029 19.8 0.3 0.0072 15.2 0.3 2.1 1 1 0 1 1 1 1 Retrotransposon hot spot protein BTRD1 PF17660.1 KIK58233.1 - 2.5e-50 168.1 20.8 1.1e-16 60.3 0.6 5.7 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 Beta-lactamase PF00144.24 KIK58233.1 - 4.3e-31 108.4 0.5 7.3e-31 107.6 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase Proteasome PF00227.26 KIK58234.1 - 1e-47 162.1 0.1 1.2e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KIK58234.1 - 1.3e-11 43.7 1.8 1.3e-11 43.7 1.8 2.1 2 1 1 3 3 3 2 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 KIK58234.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus zf-C2H2_4 PF13894.6 KIK58235.1 - 3.9e-07 30.4 14.1 0.085 13.7 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK58235.1 - 1.1e-06 28.7 19.7 0.00084 19.7 0.2 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK58235.1 - 0.01 16.3 0.8 0.01 16.3 0.8 3.7 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIK58235.1 - 0.037 14.3 6.4 1.3 9.3 1.0 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon BAG6 PF12057.8 KIK58235.1 - 0.067 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Zn_ribbon_SprT PF17283.2 KIK58235.1 - 0.079 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 KIK58235.1 - 0.11 12.6 4.3 0.4 10.7 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger GAGA PF09237.11 KIK58235.1 - 2.7 7.9 5.2 1.8 8.4 0.5 2.9 3 0 0 3 3 3 0 GAGA factor FOXP-CC PF16159.5 KIK58235.1 - 4.3 8.0 5.1 8.9 7.0 0.3 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain F-box-like PF12937.7 KIK58236.1 - 1.5e-12 47.2 0.9 1.5e-12 47.2 0.9 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK58236.1 - 7.2e-06 25.8 0.8 7.2e-06 25.8 0.8 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIK58236.1 - 0.2 12.1 4.3 19 5.8 0.1 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) p450 PF00067.22 KIK58237.1 - 1.6e-53 182.1 0.0 2.2e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK58238.1 - 5e-08 32.1 0.1 5.4e-08 32.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 KIK58239.1 - 5.4e-62 205.8 2.8 1e-21 76.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KIK58241.1 - 3.8e-65 220.4 0.0 1.3e-64 218.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FNIP PF05725.12 KIK58241.1 - 0.029 14.5 0.2 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 FNIP Repeat Thiamine_BP PF01910.17 KIK58242.1 - 2.3e-27 94.7 0.0 2.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 KIK58242.1 - 0.00021 21.7 0.0 0.00027 21.4 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family Amidase PF01425.21 KIK58244.1 - 7.6e-67 226.2 0.0 3.9e-66 223.9 0.0 2.0 1 1 0 1 1 1 1 Amidase Amidase PF01425.21 KIK58245.1 - 5.9e-68 229.9 0.0 6.6e-67 226.4 0.0 2.2 1 1 0 1 1 1 1 Amidase DUF1479 PF07350.12 KIK58246.1 - 2.1e-125 418.7 0.0 2.6e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KIK58246.1 - 0.028 14.7 0.0 0.71 10.1 0.0 2.7 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) Ras PF00071.22 KIK58247.1 - 2.7e-59 199.4 0.2 3.4e-59 199.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK58247.1 - 1.8e-37 128.2 0.1 3.1e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK58247.1 - 8.5e-16 57.9 0.1 1.1e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK58247.1 - 8.7e-07 28.5 0.1 1.1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KIK58247.1 - 4.2e-06 26.4 0.3 8.6e-05 22.2 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK58247.1 - 7.5e-06 26.0 0.1 5e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK58247.1 - 1.5e-05 24.5 0.3 1.9e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIK58247.1 - 0.00021 21.2 0.0 0.055 13.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIK58247.1 - 0.0058 16.2 0.3 0.33 10.5 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KIK58247.1 - 0.007 16.1 1.7 0.074 12.8 1.7 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 KIK58247.1 - 0.03 14.2 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DLIC PF05783.11 KIK58247.1 - 0.054 12.3 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 KIK58247.1 - 0.055 13.5 0.0 2.4 8.2 0.0 2.5 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 KIK58247.1 - 0.06 12.8 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KIK58247.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Mito_carr PF00153.27 KIK58248.1 - 6.4e-09 35.6 0.1 0.00037 20.3 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein TMEM117 PF15113.6 KIK58248.1 - 0.029 13.3 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 TMEM117 protein family Peptidase_S8 PF00082.22 KIK58249.1 - 9.4e-32 110.5 2.4 1.4e-31 109.9 2.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KIK58249.1 - 3.7e-27 94.2 1.3 4.7e-27 93.8 0.4 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain PGF-CTERM PF18204.1 KIK58249.1 - 0.033 14.2 3.6 0.073 13.1 3.6 1.6 1 0 0 1 1 1 0 PGF-CTERM motif Peptidase_S8_N PF16361.5 KIK58249.1 - 0.054 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family PEP-CTERM PF07589.11 KIK58249.1 - 0.13 12.4 3.4 0.55 10.4 3.4 2.1 1 0 0 1 1 1 0 PEP-CTERM motif S8_pro-domain PF16470.5 KIK58249.1 - 0.91 10.3 3.0 1.6 9.5 0.6 2.6 2 1 0 2 2 2 0 Peptidase S8 pro-domain APG9 PF04109.16 KIK58252.1 - 1.7e-210 700.0 8.3 2e-210 699.8 8.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2207 PF09972.9 KIK58252.1 - 0.94 8.2 2.3 20 3.8 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PI3_PI4_kinase PF00454.27 KIK58253.1 - 4.1e-36 125.1 0.1 1.5e-33 116.7 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KIK58253.1 - 2.2e-23 82.6 0.0 8.3e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TetR_C_13 PF16925.5 KIK58253.1 - 0.056 13.4 0.1 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4135 PF13575.6 KIK58253.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) AA_permease_2 PF13520.6 KIK58257.1 - 1.4e-74 251.4 31.7 1.4e-74 251.4 31.7 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK58257.1 - 3.7e-19 68.7 31.5 6.1e-19 68.0 31.5 1.3 1 1 0 1 1 1 1 Amino acid permease WD40 PF00400.32 KIK58261.1 - 1.1e-117 380.5 62.5 4.3e-10 40.0 0.4 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58261.1 - 2.5e-48 162.3 5.4 0.019 15.3 0.0 12.0 1 1 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58261.1 - 4.2e-27 93.5 17.5 0.16 12.0 0.0 12.5 12 0 0 12 12 12 9 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK58261.1 - 1.5e-19 70.1 6.4 0.2 10.6 0.0 11.6 9 3 3 12 12 12 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK58261.1 - 1.4e-09 38.1 11.8 1.3 9.6 0.0 9.0 2 2 9 11 11 11 3 PQQ-like domain Proteasome_A_N PF10584.9 KIK58261.1 - 3.5e-09 36.2 27.0 9.1 6.1 0.0 12.1 12 0 0 12 12 12 3 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KIK58261.1 - 1.1e-08 34.3 2.4 3.4 6.2 0.0 8.7 7 3 3 10 10 10 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK58261.1 - 1.2e-07 31.4 0.0 5.1 6.3 0.0 7.2 3 2 5 9 9 9 1 WD40-like domain Ret2_MD PF18528.1 KIK58261.1 - 1.5e-07 31.7 0.1 25 5.3 0.0 8.6 1 1 10 11 11 11 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KIK58261.1 - 6.8e-07 28.0 0.0 5 5.3 0.0 6.6 5 3 1 6 6 6 3 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK58261.1 - 4.2e-06 25.8 1.7 4 6.1 0.0 6.6 3 3 4 7 7 7 2 Prolyl oligopeptidase, N-terminal beta-propeller domain nos_propeller PF18764.1 KIK58261.1 - 0.0015 18.4 7.8 26 4.8 0.0 8.3 10 0 0 10 10 10 0 Nitrous oxide reductase propeller repeat DUF4873 PF16170.5 KIK58261.1 - 0.018 15.3 3.7 1.2 9.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4873) DPPIV_N PF00930.21 KIK58261.1 - 0.029 13.1 2.5 30 3.2 0.0 6.3 5 2 2 8 8 8 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4265 PF14085.6 KIK58261.1 - 0.16 11.9 6.9 17 5.4 0.0 5.8 8 1 2 10 10 9 0 Domain of unknown function (DUF4265) AAA_16 PF13191.6 KIK58262.1 - 1.5e-05 25.4 0.0 2.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK58262.1 - 3.1e-05 24.0 0.4 5.1e-05 23.3 0.4 1.4 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK58262.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK58262.1 - 0.00078 19.8 0.0 0.0063 16.9 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KIK58262.1 - 0.0024 17.6 0.0 0.0036 17.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK58262.1 - 0.0036 16.5 0.0 0.0048 16.1 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KIK58262.1 - 0.0042 16.4 0.2 0.0062 15.8 0.2 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.29 KIK58262.1 - 0.0063 16.9 0.4 0.017 15.6 0.4 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK58262.1 - 0.0082 16.7 0.1 0.015 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK58262.1 - 0.0086 16.4 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK58262.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_5 PF07728.14 KIK58262.1 - 0.019 15.0 0.0 0.6 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KIK58262.1 - 0.023 15.0 0.1 0.062 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK58262.1 - 0.025 14.7 0.3 0.033 14.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK58262.1 - 0.026 13.6 0.9 0.062 12.4 0.1 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KIK58262.1 - 0.03 14.9 0.0 0.047 14.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KIK58262.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF815 PF05673.13 KIK58262.1 - 0.058 12.5 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIK58262.1 - 0.078 12.5 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK58262.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NOA36 PF06524.12 KIK58265.1 - 1.4 8.2 7.2 2.1 7.6 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4407 PF14362.6 KIK58265.1 - 2 7.7 5.7 0.84 8.9 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AA_permease_2 PF13520.6 KIK58266.1 - 9.8e-65 219.0 24.0 1.5e-64 218.4 24.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK58266.1 - 4.3e-14 52.0 25.2 6.8e-14 51.3 25.2 1.3 1 1 0 1 1 1 1 Amino acid permease WD40 PF00400.32 KIK58267.1 - 5.9e-32 109.2 2.8 1.2e-09 38.6 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58267.1 - 2.9e-11 43.5 0.0 0.0066 16.7 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58267.1 - 1.9e-05 24.5 2.5 0.38 10.8 0.2 3.7 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK58267.1 - 0.0001 21.4 0.0 1.5 7.7 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK58267.1 - 0.035 13.8 0.7 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KIK58267.1 - 0.078 11.6 0.0 14 4.2 0.0 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 KIK58267.1 - 0.13 10.5 0.0 2.8 6.2 0.0 2.5 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK58268.1 - 7.9e-08 32.4 0.8 4.1e-07 30.1 0.0 2.4 2 1 1 3 3 3 1 NACHT domain AAA_16 PF13191.6 KIK58268.1 - 1.7e-05 25.3 0.0 6.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain WD40 PF00400.32 KIK58268.1 - 5.9e-05 23.8 0.2 0.00016 22.4 0.2 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA PF00004.29 KIK58268.1 - 0.0015 18.9 0.2 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KIK58268.1 - 0.0035 16.6 0.2 0.0095 15.2 0.2 1.6 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 KIK58268.1 - 0.0042 16.3 0.1 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 KIK58268.1 - 0.0085 16.5 0.0 0.044 14.2 0.0 2.2 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 KIK58268.1 - 0.0086 16.0 0.0 0.0086 16.0 0.0 3.0 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIK58268.1 - 0.034 13.8 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK58268.1 - 0.035 14.4 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK58268.1 - 0.04 13.1 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KIK58268.1 - 0.057 13.2 0.9 2.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KIK58268.1 - 0.064 13.8 0.0 0.26 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK58268.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK58268.1 - 0.09 12.8 0.3 4.3 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KIK58268.1 - 0.14 12.0 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AA_permease_2 PF13520.6 KIK58271.1 - 3e-58 197.6 28.2 8e-58 196.3 25.9 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK58271.1 - 9.4e-13 47.6 21.4 1.5e-12 46.9 21.4 1.3 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.32 KIK58272.1 - 1.6e-38 130.0 15.0 5.9e-10 39.6 0.3 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58272.1 - 1.5e-15 57.3 0.3 0.012 15.9 0.0 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58272.1 - 2.2e-06 27.5 6.7 0.59 10.1 0.1 4.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK58272.1 - 8e-05 22.5 1.9 0.0097 15.7 0.3 3.2 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK58272.1 - 0.00035 20.0 0.0 8.6 5.6 0.0 3.4 3 0 0 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 KIK58272.1 - 0.0005 19.1 0.1 6.5 5.6 0.0 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK58272.1 - 0.096 12.4 3.4 63 3.4 0.0 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Cuticle_4 PF15955.5 KIK58272.1 - 0.12 13.1 0.8 68 4.3 0.0 3.9 4 0 0 4 4 4 0 Cuticle protein AAA_16 PF13191.6 KIK58273.1 - 8.4e-07 29.5 0.0 9.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK58273.1 - 7.5e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KIK58273.1 - 1.9e-05 24.6 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK58273.1 - 0.00017 21.9 0.0 0.00023 21.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK58273.1 - 0.0003 20.1 0.0 0.00039 19.7 0.0 1.2 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK58273.1 - 0.001 19.5 0.1 0.0021 18.5 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KIK58273.1 - 0.0015 17.6 0.1 0.0029 16.8 0.1 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KIK58273.1 - 0.0034 17.9 0.0 0.0047 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK58273.1 - 0.0039 17.7 0.0 0.0056 17.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KIK58273.1 - 0.0067 16.2 0.1 0.0067 16.2 0.1 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK58273.1 - 0.0098 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KIK58273.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KIK58273.1 - 0.011 15.5 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase APS_kinase PF01583.20 KIK58273.1 - 0.018 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PIF1 PF05970.14 KIK58273.1 - 0.026 13.7 0.1 0.04 13.1 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase Zeta_toxin PF06414.12 KIK58273.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 KIK58273.1 - 0.032 14.2 0.1 0.041 13.8 0.1 1.5 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 KIK58273.1 - 0.056 13.6 0.3 0.069 13.3 0.3 1.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK58273.1 - 0.062 12.5 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 KIK58273.1 - 0.07 13.0 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2095 PF09868.9 KIK58273.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Sigma54_activ_2 PF14532.6 KIK58273.1 - 0.085 13.0 0.0 0.73 10.0 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KIK58273.1 - 0.086 13.3 0.2 0.24 11.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK58273.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK58273.1 - 0.12 11.6 0.3 0.26 10.5 0.1 1.5 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.16 KIK58273.1 - 0.17 11.3 0.1 0.2 11.1 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein CbiA PF01656.23 KIK58273.1 - 0.22 11.6 0.4 0.44 10.6 0.2 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3963 PF13124.6 KIK58274.1 - 0.034 14.1 0.4 0.055 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AA_permease_2 PF13520.6 KIK58277.1 - 2.6e-73 247.3 32.9 3.7e-73 246.8 32.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK58277.1 - 7.6e-18 64.4 30.7 1.2e-17 63.7 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease NACHT PF05729.12 KIK58278.1 - 8.8e-07 29.0 0.4 1.3e-06 28.4 0.4 1.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58278.1 - 1.1e-05 25.9 0.0 1.5e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK58278.1 - 0.00069 19.9 0.0 0.00095 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK58278.1 - 0.00079 19.9 0.3 0.002 18.5 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KIK58278.1 - 0.00082 18.7 0.5 0.0011 18.2 0.5 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 KIK58278.1 - 0.0026 17.0 0.0 0.0029 16.9 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK58278.1 - 0.0063 16.9 0.1 0.03 14.7 0.0 2.0 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KIK58278.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK58278.1 - 0.025 14.8 0.0 0.03 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK58278.1 - 0.033 14.2 0.0 0.76 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK58278.1 - 0.033 13.9 0.0 0.04 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK58278.1 - 0.073 13.4 0.1 0.13 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK58278.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 KIK58278.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KIK58278.1 - 0.18 11.5 0.5 0.33 10.7 0.2 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KIK58278.1 - 0.47 10.5 2.4 0.99 9.4 0.1 2.1 2 1 0 2 2 2 0 Helicase HerA, central domain CENP-F_leu_zip PF10473.9 KIK58281.1 - 0.049 13.7 1.3 0.11 12.6 1.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CBFD_NFYB_HMF PF00808.23 KIK58283.1 - 7.9e-09 35.7 0.1 1.3e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KIK58283.1 - 0.015 15.4 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF4407 PF14362.6 KIK58283.1 - 8.9 5.6 7.2 0.78 9.0 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.6 KIK58284.1 - 1.4e-05 24.9 28.3 0.0001 22.1 14.3 2.7 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK58284.1 - 0.00033 20.5 11.6 0.00033 20.5 11.6 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C2H2_jaz PF12171.8 KIK58284.1 - 0.0013 18.9 19.2 0.0085 16.4 1.7 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.6 KIK58284.1 - 0.0022 18.3 17.4 0.0022 18.3 17.4 3.0 2 2 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK58284.1 - 0.0028 17.4 17.9 0.0028 17.4 17.9 3.5 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 KIK58284.1 - 0.0029 18.3 22.7 0.03 15.1 0.9 4.9 5 0 0 5 5 4 2 C2H2-type zinc finger zf-C3HC4 PF00097.25 KIK58284.1 - 0.0082 16.0 17.0 0.0082 16.0 17.0 3.2 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK58284.1 - 0.011 15.6 7.0 0.027 14.4 7.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 KIK58284.1 - 0.019 15.4 23.1 0.15 12.5 1.4 4.9 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.6 KIK58284.1 - 0.029 14.4 8.6 0.029 14.4 8.6 3.6 2 2 1 3 3 3 0 RING-type zinc-finger FYVE PF01363.21 KIK58284.1 - 0.045 13.9 20.3 0.025 14.7 7.8 3.2 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.6 KIK58284.1 - 0.38 10.7 9.9 0.97 9.4 0.8 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C3HC4_4 PF15227.6 KIK58284.1 - 0.78 9.9 24.7 0.23 11.7 8.3 4.4 4 1 1 5 5 4 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KIK58284.1 - 3.3 7.0 9.8 0.11 11.9 3.0 1.9 2 1 0 2 2 2 0 Rtf2 RING-finger Zn-C2H2_12 PF18112.1 KIK58284.1 - 5.3 7.6 11.7 6.3 7.4 0.3 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Apc15p PF05841.11 KIK58286.1 - 0.0072 17.1 0.5 0.013 16.3 0.0 1.6 2 0 0 2 2 2 1 Apc15p protein Na_trans_assoc PF06512.13 KIK58286.1 - 0.025 14.9 7.5 0.03 14.6 7.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DHHA1 PF02272.19 KIK58286.1 - 0.079 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 DHHA1 domain RRN3 PF05327.11 KIK58286.1 - 5.6 5.4 8.8 8.7 4.7 8.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.13 KIK58287.1 - 2.2e-17 63.6 0.0 3.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK58287.1 - 2.2e-14 53.1 0.0 4.6e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK58287.1 - 0.07 12.0 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF1682 PF07946.14 KIK58288.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Abhydrolase_1 PF00561.20 KIK58289.1 - 6.4e-15 55.5 0.0 9.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK58289.1 - 9.7e-13 49.2 0.0 1.3e-12 48.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK58289.1 - 1.1e-05 24.8 0.0 0.00015 21.1 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 TAP42 PF04177.12 KIK58290.1 - 1.9e-87 293.4 0.2 2.2e-87 293.2 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family ELM2 PF01448.24 KIK58290.1 - 0.048 14.4 0.0 0.21 12.3 0.0 2.2 1 1 0 1 1 1 0 ELM2 domain FMO-like PF00743.19 KIK58291.1 - 1.6e-21 76.3 0.0 3.4e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK58291.1 - 5.6e-10 39.0 0.0 7.5e-08 32.0 0.0 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK58291.1 - 1.1e-08 35.1 1.1 0.00035 20.3 0.1 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK58291.1 - 7.6e-08 31.9 0.0 0.00033 20.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK58291.1 - 2.1e-06 27.8 0.1 0.00014 21.9 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK58291.1 - 9e-05 22.6 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIK58291.1 - 0.0013 17.9 0.0 3 6.9 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Glu_dehyd_C PF16912.5 KIK58291.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Amino_oxidase PF01593.24 KIK58291.1 - 0.036 13.4 0.2 7.4 5.7 0.0 3.2 3 1 1 4 4 4 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KIK58291.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KIK58291.1 - 0.076 13.6 0.1 0.58 10.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAT PF03417.16 KIK58296.1 - 1.7e-23 83.5 0.0 3.2e-23 82.6 0.0 1.4 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Transket_pyr PF02779.24 KIK58297.1 - 1.6e-33 115.8 0.1 1.3e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIK58297.1 - 4.9e-23 81.3 0.0 2.8e-17 62.7 0.0 2.3 2 0 0 2 2 2 2 Transketolase, C-terminal domain O-FucT PF10250.9 KIK58300.1 - 8.9e-05 22.3 0.0 0.00049 19.9 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pro-kuma_activ PF09286.11 KIK58301.1 - 6.8e-30 104.2 0.1 1.2e-29 103.5 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK58301.1 - 2.2e-06 27.2 2.4 4.2e-06 26.2 2.4 1.4 1 0 0 1 1 1 1 Subtilase family GPI-anchored PF10342.9 KIK58302.1 - 3.1e-10 40.7 0.0 4.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cu-oxidase PF00394.22 KIK58304.1 - 1.5e-37 129.1 0.0 4.6e-37 127.6 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK58304.1 - 2.1e-34 118.2 0.1 2e-32 111.8 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK58304.1 - 1.2e-27 96.3 0.1 1.2e-25 89.9 0.0 2.7 2 0 0 2 2 2 1 Multicopper oxidase Peptidase_M28 PF04389.17 KIK58307.1 - 2.7e-36 125.1 0.0 6.6e-36 123.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 WD40 PF00400.32 KIK58309.1 - 4.7e-128 413.3 57.7 1.6e-09 38.2 0.3 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58309.1 - 8.8e-45 150.9 7.2 0.031 14.6 0.0 14.6 2 1 12 15 15 14 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58309.1 - 1.2e-20 72.9 21.8 2.6 8.1 0.0 13.4 14 0 0 14 14 13 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK58309.1 - 1.2e-18 67.2 0.1 2.8 6.8 0.0 12.6 11 3 3 14 14 14 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK58309.1 - 8.9e-12 44.9 0.0 0.81 9.0 0.0 6.7 4 1 4 8 8 8 4 WD40-like domain Nup160 PF11715.8 KIK58309.1 - 1e-06 27.7 8.8 3.4 6.2 0.0 9.8 5 3 8 13 13 13 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KIK58309.1 - 6.3e-05 22.6 23.5 18 5.2 0.0 11.1 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KIK58309.1 - 7.5e-05 22.7 0.0 0.0003 20.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK58309.1 - 0.00029 21.3 0.0 0.00078 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK58309.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PQQ_3 PF13570.6 KIK58309.1 - 0.006 17.0 14.7 13 6.4 0.1 8.0 4 2 5 9 9 9 0 PQQ-like domain AAA_30 PF13604.6 KIK58309.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK58309.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK58309.1 - 0.04 13.1 0.1 0.073 12.2 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KIK58309.1 - 0.047 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 KIK58309.1 - 0.059 13.1 0.0 15 5.3 0.0 3.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIK58309.1 - 0.11 12.9 0.0 0.53 10.7 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KIK58309.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK58309.1 - 0.15 11.9 0.1 0.42 10.5 0.1 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase SGL PF08450.12 KIK58310.1 - 7.9e-09 35.4 0.1 2.5e-08 33.8 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Ykof PF07615.11 KIK58310.1 - 0.063 13.8 0.0 10 6.7 0.0 2.4 2 0 0 2 2 2 0 YKOF-related Family Reg_prop PF07494.11 KIK58310.1 - 0.17 12.2 0.1 2.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Two component regulator propeller Peptidase_M28 PF04389.17 KIK58311.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M28 WD40 PF00400.32 KIK58313.1 - 6.4e-127 409.8 55.6 3.4e-10 40.3 0.1 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58313.1 - 2.5e-52 175.1 9.7 0.0002 21.6 0.0 12.0 2 2 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58313.1 - 1.5e-28 98.1 16.3 0.88 9.6 0.2 12.8 12 0 0 12 12 12 10 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK58313.1 - 9.7e-20 70.8 0.7 3.6 6.5 0.0 11.6 10 2 2 12 12 12 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK58313.1 - 3.3e-11 43.4 21.2 0.2 11.4 0.2 8.9 1 1 6 7 7 7 7 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK58313.1 - 6e-11 42.2 0.0 2.4 7.4 0.0 7.8 2 1 9 11 11 11 3 WD40-like domain Proteasome_A_N PF10584.9 KIK58313.1 - 2.4e-10 39.9 17.7 6 6.6 0.1 11.9 12 0 0 12 12 12 1 Proteasome subunit A N-terminal signature Ret2_MD PF18528.1 KIK58313.1 - 2.6e-08 34.1 0.0 38 4.7 0.0 9.0 2 2 10 12 12 12 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KIK58313.1 - 1.8e-05 23.3 0.0 40 2.3 0.0 7.6 8 2 2 10 10 10 0 WD repeat-containing and planar cell polarity effector protein Fritz MMS1_N PF10433.9 KIK58313.1 - 2.4e-05 23.2 0.0 0.79 8.3 0.0 4.9 2 2 3 5 5 5 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cuticle_4 PF15955.5 KIK58313.1 - 0.00016 22.3 14.9 4.7 8.0 0.0 7.2 9 0 0 9 9 8 3 Cuticle protein Peptidase_S9_N PF02897.15 KIK58313.1 - 0.009 14.8 1.8 11 4.7 0.0 5.1 3 3 4 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 KIK58313.1 - 0.11 11.1 11.4 15 4.0 0.0 7.7 5 3 5 11 11 11 0 Nucleoporin Nup120/160 Rpn3_C PF08375.11 KIK58313.1 - 0.13 12.7 0.0 1.2e+02 3.2 0.0 4.7 5 0 0 5 5 5 0 Proteasome regulatory subunit C-terminal DUF1513 PF07433.11 KIK58313.1 - 0.99 8.4 3.6 17 4.3 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) DUF4875 PF16175.5 KIK58313.1 - 6.2 7.0 19.3 66 3.7 0.1 8.3 4 3 6 12 12 12 0 Domain of unknown function (DUF4875) DUF202 PF02656.15 KIK58314.1 - 0.00063 20.1 0.3 0.00094 19.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) RTA1 PF04479.13 KIK58314.1 - 0.0067 16.1 0.0 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Phage_holin_3_6 PF07332.11 KIK58314.1 - 0.078 13.0 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Meckelin PF09773.9 KIK58314.1 - 0.098 10.7 0.1 0.12 10.5 0.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) MARVEL PF01284.23 KIK58314.1 - 0.13 12.2 0.4 0.17 11.9 0.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain MgtC PF02308.16 KIK58314.1 - 0.15 12.4 0.1 0.19 12.1 0.1 1.1 1 0 0 1 1 1 0 MgtC family Cadherin_C_2 PF16492.5 KIK58314.1 - 0.19 12.5 0.0 0.36 11.6 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RCR PF12273.8 KIK58315.1 - 0.15 12.7 10.3 0.2 12.3 10.3 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CAP_N PF01213.19 KIK58315.1 - 4.7 6.6 5.7 5.4 6.4 5.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_C14 PF00656.22 KIK58316.1 - 1.2e-53 182.6 0.0 1.9e-53 182.0 0.0 1.3 1 1 0 1 1 1 1 Caspase domain SH2_2 PF14633.6 KIK58316.1 - 0.00049 19.6 0.3 0.00083 18.8 0.3 1.3 1 0 0 1 1 1 1 SH2 domain Raptor_N PF14538.6 KIK58316.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Peptidase_C13 PF01650.18 KIK58316.1 - 0.17 11.4 0.6 3 7.3 0.0 2.6 2 1 1 3 3 3 0 Peptidase C13 family Transp_cyt_pur PF02133.15 KIK58317.1 - 4.7e-82 276.1 39.8 1.5e-81 274.5 39.8 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin peroxidase PF00141.23 KIK58318.1 - 2.6e-20 73.1 0.1 4.7e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 KIK58318.1 - 0.083 12.9 0.8 0.4 10.7 0.1 2.2 1 1 1 2 2 2 0 Photosystem I psaG / psaK WD40 PF00400.32 KIK58319.1 - 1.4e-10 41.6 7.3 0.0023 18.7 0.1 6.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58319.1 - 9.1e-06 25.9 0.0 0.005 17.1 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK58319.1 - 0.0054 15.3 0.0 0.014 13.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK58319.1 - 0.81 9.7 0.0 0.81 9.7 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat p450 PF00067.22 KIK58322.1 - 3.8e-65 220.4 0.0 7.1e-65 219.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KIK58323.1 - 6.6e-13 48.8 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK58323.1 - 6.3e-07 29.3 0.0 6.4e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK58323.1 - 0.00016 22.7 0.0 0.001 20.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK58323.1 - 0.031 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase eIF3m_C_helix PF18005.1 KIK58323.1 - 0.081 12.6 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix ADH_zinc_N PF00107.26 KIK58324.1 - 6.3e-14 52.1 0.1 1.1e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK58324.1 - 0.00027 20.8 0.0 0.0019 18.0 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK58324.1 - 0.0057 17.7 0.0 0.01 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase eIF3m_C_helix PF18005.1 KIK58324.1 - 0.028 14.1 0.2 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix ADH_N_2 PF16884.5 KIK58324.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short PF00106.25 KIK58325.1 - 1.5e-35 122.4 0.6 2.8e-35 121.6 0.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK58325.1 - 5.9e-33 114.4 1.1 1.2e-32 113.3 1.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK58325.1 - 7.1e-09 35.8 0.2 1.5e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK58325.1 - 0.0033 17.3 0.2 0.0097 15.8 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIK58325.1 - 0.0068 16.9 1.7 0.34 11.5 0.1 3.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 KIK58325.1 - 0.019 14.4 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIK58325.1 - 0.039 13.3 0.0 0.077 12.4 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK58325.1 - 0.096 12.1 0.1 0.49 9.8 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KIK58327.1 - 5.3e-07 29.4 0.3 5.3e-07 29.4 0.3 3.5 4 1 0 4 4 4 1 F-box-like F-box PF00646.33 KIK58327.1 - 0.036 14.0 0.3 12 5.9 0.0 3.8 3 1 1 4 4 4 0 F-box domain LRR_4 PF12799.7 KIK58327.1 - 0.048 14.1 1.4 4.3 7.9 0.5 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_1 PF00232.18 KIK58329.1 - 1.2e-104 350.2 0.0 1.7e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 WD40 PF00400.32 KIK58330.1 - 1.5e-93 304.1 37.8 1.7e-09 38.1 0.4 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58330.1 - 1.3e-33 115.1 3.5 1.4e-05 25.3 0.0 10.8 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58330.1 - 3.3e-15 55.6 7.3 0.28 11.2 0.0 9.7 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK58330.1 - 7.8e-13 48.1 3.1 0.29 10.1 0.0 8.8 3 2 7 10 10 10 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK58330.1 - 3.1e-11 42.7 7.1 0.56 8.8 0.0 9.3 8 3 2 10 10 10 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KIK58330.1 - 2.3e-06 27.6 0.6 21 5.2 0.0 8.3 10 1 0 10 10 10 0 Ciliary BBSome complex subunit 2, middle region DUF4072 PF13284.6 KIK58330.1 - 4.7e-06 26.9 0.9 53 4.4 0.0 8.4 11 0 0 11 11 11 0 Domain of unknown function (DUF4072) DUF4265 PF14085.6 KIK58330.1 - 0.00097 19.1 0.5 11 6.1 0.0 5.2 5 2 1 6 6 5 1 Domain of unknown function (DUF4265) eIF2A PF08662.11 KIK58330.1 - 0.0011 18.9 0.1 0.38 10.6 0.0 3.6 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF4784 PF16023.5 KIK58330.1 - 0.0017 17.4 0.0 6.8 5.5 0.0 4.6 2 1 2 5 5 5 1 Domain of unknown function (DUF4784) WD40_like PF17005.5 KIK58330.1 - 0.0018 17.7 0.0 50 3.1 0.0 5.5 6 0 0 6 6 6 0 WD40-like domain Glyco_hydro_30C PF17189.4 KIK58330.1 - 0.02 15.1 8.2 1.1 9.5 0.2 5.1 4 3 1 5 5 5 0 Glycosyl hydrolase family 30 beta sandwich domain Peptidase_S9_N PF02897.15 KIK58330.1 - 0.025 13.4 3.1 6.2 5.5 0.0 4.9 4 3 2 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 KIK58330.1 - 0.088 12.5 1.5 62 3.4 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Me-amine-dh_H PF06433.11 KIK58330.1 - 0.097 11.5 0.0 43 2.8 0.0 4.3 4 3 2 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.6 KIK58330.1 - 0.15 11.3 1.0 7.8 5.7 0.0 3.6 2 2 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal CinA PF02464.17 KIK58331.1 - 6.5e-27 94.0 0.0 3.8e-26 91.5 0.0 1.9 1 1 0 1 1 1 1 Competence-damaged protein Acetyltransf_1 PF00583.25 KIK58332.1 - 6.7e-13 48.9 0.0 8.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK58332.1 - 1.6e-10 41.0 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK58332.1 - 1.7e-09 37.9 0.0 2.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK58332.1 - 0.014 15.4 0.0 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein DUF444 PF04285.12 KIK58333.1 - 0.027 13.6 0.3 0.059 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF444) DUF908 PF06012.12 KIK58333.1 - 8.2 5.7 8.6 11 5.3 8.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) adh_short PF00106.25 KIK58335.1 - 3e-37 128.0 0.8 5.5e-37 127.1 0.3 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK58335.1 - 1.4e-34 119.7 0.3 3e-34 118.6 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK58335.1 - 1.7e-08 34.6 0.1 4e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.27 KIK58335.1 - 0.00069 20.1 0.8 0.0075 16.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KIK58335.1 - 0.0011 18.5 0.1 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK58335.1 - 0.0012 18.3 0.1 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KIK58335.1 - 0.0017 18.2 0.1 0.0051 16.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KIK58335.1 - 0.003 17.0 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HATPase_c PF02518.26 KIK58335.1 - 0.04 14.4 1.1 2 9.0 0.1 2.4 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ADH_zinc_N PF00107.26 KIK58336.1 - 2.2e-15 56.8 0.0 1.7e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK58336.1 - 1.8e-07 31.0 0.0 2.8e-06 27.2 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK58336.1 - 1.6e-06 29.2 0.0 4e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK58336.1 - 0.047 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Sec63 PF02889.16 KIK58337.1 - 4.9e-30 104.6 0.2 8e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIK58337.1 - 3.7e-25 88.7 0.0 4.5e-24 85.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK58337.1 - 3.4e-11 43.4 0.0 8.5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK58337.1 - 0.00016 22.0 0.0 0.00065 20.0 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK58337.1 - 0.013 15.8 0.3 0.12 12.7 0.3 2.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK58337.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIK58337.1 - 0.029 13.4 0.0 0.094 11.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 KIK58337.1 - 0.061 13.7 0.0 0.23 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain CKS PF01111.19 KIK58338.1 - 1.6e-34 118.0 0.6 2e-34 117.6 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16 PF00675.20 KIK58339.1 - 4.7e-14 52.6 0.0 4.4e-13 49.5 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK58339.1 - 2.9e-08 33.9 0.0 6.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 KIK58340.1 - 6.5e-90 301.2 0.3 2.1e-88 296.3 0.1 2.2 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KIK58340.1 - 3.6e-37 127.6 1.4 1.2e-36 125.9 0.1 2.5 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK58340.1 - 1.8e-22 80.2 0.0 1.5e-09 38.2 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain KDZ PF18758.1 KIK58341.1 - 6.4e-25 88.1 1.2 7e-25 87.9 1.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Ste5 PF11610.8 KIK58344.1 - 0.052 13.4 8.6 0.58 10.1 0.6 2.8 2 1 1 3 3 3 0 Scaffold protein Ste5, Fus3-binding region Retrotrans_gag PF03732.17 KIK58346.1 - 5.8e-07 29.7 0.0 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK58346.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) ELFV_dehydrog PF00208.21 KIK58347.1 - 1.3e-72 244.5 0.3 1.5e-72 244.2 0.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KIK58347.1 - 4.7e-50 168.8 0.0 8.5e-50 168.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NOGCT PF08155.11 KIK58347.1 - 0.075 13.0 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 NOGCT (NUC087) domain Microtub_bind PF13931.6 KIK58348.1 - 2.9 8.3 6.2 42 4.5 0.1 3.2 2 2 1 3 3 3 0 Kinesin-associated microtubule-binding Pec_lyase_C PF00544.19 KIK58349.1 - 3.2e-27 95.5 1.3 1.1e-26 93.8 0.1 2.0 1 1 1 2 2 2 1 Pectate lyase RVT_1 PF00078.27 KIK58350.1 - 0.062 12.8 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Transp_cyt_pur PF02133.15 KIK58351.1 - 4.2e-27 95.0 35.9 7.2e-27 94.2 35.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Flavin_Reduct PF01613.18 KIK58354.1 - 1.9e-15 57.3 0.2 2.9e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Amidohydro_3 PF07969.11 KIK58355.1 - 0.086 12.3 0.0 0.086 12.3 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase family p450 PF00067.22 KIK58356.1 - 8.4e-49 166.5 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_3 PF07969.11 KIK58357.1 - 9e-16 58.4 0.0 9.1e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIK58357.1 - 5.7e-08 32.5 0.0 6.5e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family p450 PF00067.22 KIK58359.1 - 1.5e-57 195.4 0.0 2e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_3 PF07969.11 KIK58361.1 - 9.9e-79 266.0 0.0 1.3e-78 265.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIK58361.1 - 6e-14 52.1 0.0 5e-12 45.8 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family YflT PF11181.8 KIK58361.1 - 0.061 13.8 0.0 9.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Heat induced stress protein YflT p450 PF00067.22 KIK58362.1 - 1.1e-45 156.3 0.0 1.4e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DER1 PF04511.15 KIK58363.1 - 0.00033 20.6 0.1 0.00043 20.3 0.1 1.1 1 0 0 1 1 1 1 Der1-like family p450 PF00067.22 KIK58364.1 - 6.1e-57 193.4 0.0 8.3e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DER1 PF04511.15 KIK58365.1 - 3.7e-32 111.8 1.2 4.6e-32 111.5 1.2 1.0 1 0 0 1 1 1 1 Der1-like family p450 PF00067.22 KIK58366.1 - 1.3e-48 165.9 0.0 1.7e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.6 KIK58369.1 - 1.9e-06 28.1 7.9 3.5e-06 27.2 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KIK58369.1 - 1.7e-05 24.9 4.1 3.6e-05 23.9 4.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KIK58369.1 - 0.0026 17.8 1.4 0.0058 16.7 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK58369.1 - 0.0065 16.7 7.0 0.014 15.6 7.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain PP28 PF10252.9 KIK58369.1 - 0.055 13.9 0.8 1 9.9 1.6 2.4 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Zn_ribbon_17 PF17120.5 KIK58369.1 - 0.096 12.3 5.0 0.2 11.3 5.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KIK58369.1 - 0.1 12.9 6.6 0.21 11.9 6.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KIK58369.1 - 0.15 12.0 8.4 0.26 11.2 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KIK58369.1 - 0.22 11.7 6.0 0.41 10.8 6.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 KIK58369.1 - 0.26 11.2 7.9 0.5 10.3 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KIK58369.1 - 0.61 10.0 4.3 0.34 10.8 2.1 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4589 PF15252.6 KIK58369.1 - 1.7 8.6 10.0 0.076 13.0 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) zf-RING_4 PF14570.6 KIK58369.1 - 4.5 7.1 5.2 8.4 6.3 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ArsP_1 PF03773.13 KIK58373.1 - 0.056 12.6 0.1 0.59 9.2 0.0 1.9 2 0 0 2 2 2 0 Predicted permease Rhabdo_M2 PF04785.12 KIK58381.1 - 0.015 14.7 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 gag_pre-integrs PF13976.6 KIK58386.1 - 2.1e-06 27.5 0.1 3.3e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KIK58386.1 - 0.077 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Cro PF09048.10 KIK58395.1 - 0.0059 16.6 0.1 0.35 11.0 0.0 2.8 2 1 1 3 3 3 1 Cro Glyco_hydro_15 PF00723.21 KIK58401.1 - 0.0037 16.1 0.0 0.0094 14.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 NACHT PF05729.12 KIK58405.1 - 0.00019 21.4 0.0 0.00029 20.8 0.0 1.4 1 1 0 1 1 1 1 NACHT domain YdjC PF04794.12 KIK58405.1 - 0.068 13.2 0.0 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 YdjC-like protein DEAD PF00270.29 KIK58405.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 KIK58406.1 - 5.8e-05 23.1 0.0 7.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK58406.1 - 6e-05 23.5 0.0 7.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK58406.1 - 0.0017 18.7 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIK58406.1 - 0.0085 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KIK58406.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KIK58406.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_PrkA PF08298.11 KIK58406.1 - 0.021 13.8 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain AAA_7 PF12775.7 KIK58406.1 - 0.031 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIK58406.1 - 0.044 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK58406.1 - 0.046 14.2 0.0 0.062 13.7 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK58406.1 - 0.049 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KIK58406.1 - 0.071 13.6 0.0 0.085 13.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KIK58406.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KIK58406.1 - 0.081 12.4 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KIK58406.1 - 0.081 12.2 0.1 0.34 10.2 0.0 1.8 1 1 1 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 KIK58406.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KIK58406.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 KIK58406.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_25 PF13481.6 KIK58406.1 - 0.18 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK58406.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KIK58406.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 KIK58406.1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KIK58407.1 - 1.5e-35 122.5 0.5 3.8e-35 121.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK58407.1 - 7.1e-19 68.2 0.1 4e-17 62.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK58407.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TOBE PF03459.17 KIK58407.1 - 0.14 12.5 0.0 0.55 10.6 0.0 2.0 1 1 0 1 1 1 0 TOBE domain DUF1390 PF07150.11 KIK58407.1 - 0.2 11.3 0.2 0.67 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) bZIP_1 PF00170.21 KIK58408.1 - 0.00027 20.9 10.6 0.00049 20.1 10.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK58408.1 - 0.00059 19.9 11.9 0.00095 19.2 11.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.9 KIK58408.1 - 0.061 11.9 8.6 0.073 11.6 8.6 1.0 1 0 0 1 1 1 0 Macoilin family CCD PF07860.11 KIK58408.1 - 4.3 7.4 5.9 5.1 7.1 2.6 2.2 1 1 1 2 2 2 0 WisP family C-Terminal Region ABC_tran PF00005.27 KIK58409.1 - 3.8e-42 144.1 0.2 8.1e-26 91.2 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK58409.1 - 1.7e-40 139.5 27.0 3.4e-21 76.1 6.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK58409.1 - 1.1e-11 44.7 4.9 0.011 15.2 2.8 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK58409.1 - 2.2e-06 28.2 0.7 0.073 13.5 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK58409.1 - 4.8e-06 26.6 5.5 0.11 12.3 0.4 4.2 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK58409.1 - 4.9e-06 26.2 0.3 0.087 12.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK58409.1 - 1.1e-05 26.1 0.2 0.0083 16.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK58409.1 - 1.4e-05 24.8 0.0 0.28 10.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KIK58409.1 - 9.9e-05 21.5 7.6 0.0047 16.0 0.1 3.3 2 1 0 3 3 3 2 Type II/IV secretion system protein AAA_22 PF13401.6 KIK58409.1 - 0.00013 22.2 0.2 0.76 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIK58409.1 - 0.0011 19.0 0.6 0.11 12.6 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK58409.1 - 0.0017 18.3 0.2 0.9 9.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KIK58409.1 - 0.0021 17.6 0.1 0.94 9.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 KIK58409.1 - 0.0023 17.6 1.4 0.63 9.6 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KIK58409.1 - 0.0026 17.7 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 KIK58409.1 - 0.0038 16.1 0.1 0.34 9.6 0.0 2.4 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF87 PF01935.17 KIK58409.1 - 0.0048 17.0 0.8 0.072 13.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Pox_A32 PF04665.12 KIK58409.1 - 0.01 15.3 0.7 1.5 8.2 0.0 2.6 2 0 0 2 2 2 1 Poxvirus A32 protein DEAD PF00270.29 KIK58409.1 - 0.012 15.4 0.3 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 KIK58409.1 - 0.013 15.9 0.0 0.57 10.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KIK58409.1 - 0.021 14.9 1.7 3.2 7.8 0.2 2.4 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KIK58409.1 - 0.04 14.5 0.0 2.9 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK58409.1 - 0.042 13.6 0.0 8.5 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK58409.1 - 0.055 13.2 0.4 12 5.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK58409.1 - 0.06 13.3 0.5 59 3.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KIK58409.1 - 0.067 12.5 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MeaB PF03308.16 KIK58409.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KIK58409.1 - 0.09 12.5 0.3 22 4.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 KIK58409.1 - 0.12 11.3 0.3 5.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KIK58409.1 - 0.16 11.2 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 KIK58409.1 - 0.26 10.5 0.9 2.3 7.4 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KIK58410.1 - 5.4e-41 140.3 0.2 3.4e-26 92.4 0.2 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK58410.1 - 8.6e-21 74.8 23.0 9.1e-08 32.1 0.1 3.6 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KIK58410.1 - 3.8e-09 36.3 2.6 0.13 11.7 0.0 5.1 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KIK58410.1 - 4e-06 26.1 0.6 0.014 14.5 0.0 3.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_25 PF13481.6 KIK58410.1 - 5.9e-06 26.0 0.1 0.63 9.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIK58410.1 - 1.2e-05 25.8 0.2 0.076 13.4 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIK58410.1 - 8.5e-05 22.2 1.2 0.21 11.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK58410.1 - 0.00056 20.5 0.8 0.11 13.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK58410.1 - 0.00063 20.0 0.5 2.1 8.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_21 PF13304.6 KIK58410.1 - 0.00066 19.6 2.9 2.7 7.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KIK58410.1 - 0.0033 17.5 1.8 0.017 15.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 KIK58410.1 - 0.0072 16.4 0.1 6 6.9 0.2 2.4 2 0 0 2 2 2 2 Dynamin family cobW PF02492.19 KIK58410.1 - 0.013 15.1 1.4 1.3 8.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KIK58410.1 - 0.016 14.7 0.3 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KIK58410.1 - 0.019 14.5 1.2 1.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KIK58410.1 - 0.027 14.4 0.2 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Adeno_IVa2 PF02456.15 KIK58410.1 - 0.034 13.0 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.18 KIK58410.1 - 0.043 13.2 0.3 4 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KIK58410.1 - 0.045 14.3 0.0 10 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK58410.1 - 0.048 13.7 2.4 0.36 10.9 0.1 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 KIK58410.1 - 0.057 12.3 0.5 9.8 5.0 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KIK58410.1 - 0.084 12.6 0.3 9.4 6.0 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 KIK58410.1 - 0.088 13.2 0.2 3.5 8.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIK58410.1 - 0.2 11.3 0.3 12 5.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK58410.1 - 0.24 11.4 0.6 34 4.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) dCMP_cyt_deam_1 PF00383.23 KIK58411.1 - 1.8e-08 34.1 0.1 4.1e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK58411.1 - 7.8e-06 25.7 0.0 6.7e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KIK58411.1 - 0.045 13.8 1.4 0.12 12.4 1.4 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Cyclase PF04199.13 KIK58412.1 - 4e-13 49.8 0.0 5.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.25 KIK58413.1 - 2.3e-12 46.8 0.1 3.5e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK58413.1 - 2.8e-05 23.8 0.0 6.1e-05 22.7 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KIK58413.1 - 0.058 12.5 0.2 0.35 9.9 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 KIK58413.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 KR domain DDE_Tnp_4 PF13359.6 KIK58415.1 - 4.8e-10 39.3 0.0 5.1e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2428 PF10350.9 KIK58416.1 - 0.00021 20.7 4.1 0.00031 20.1 4.1 1.3 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) X PF00739.19 KIK58416.1 - 0.055 13.6 5.3 0.07 13.3 4.7 1.4 1 1 0 1 1 1 0 Trans-activation protein X Retrotran_gag_2 PF14223.6 KIK58417.1 - 7.9e-10 38.5 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KIK58417.1 - 0.077 12.7 3.6 0.16 11.7 3.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK58417.1 - 1.5 9.1 6.5 0.67 10.1 4.1 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KIK58422.1 - 0.0053 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 KIK58422.1 - 0.19 11.9 1.4 0.46 10.7 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF3394 PF11874.8 KIK58422.1 - 0.2 11.3 0.7 0.44 10.2 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) HMMR_N PF15905.5 KIK58424.1 - 0.011 15.2 4.7 0.018 14.5 4.7 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Peptidase_S49_N PF08496.10 KIK58424.1 - 0.011 15.7 0.2 0.032 14.3 0.2 1.6 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK58424.1 - 0.033 14.6 5.6 0.049 14.1 5.6 1.2 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KIK58424.1 - 0.046 12.6 6.5 0.066 12.1 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KIK58424.1 - 0.13 10.2 0.6 0.17 9.8 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 KIK58424.1 - 0.14 12.2 4.8 3.3 7.9 0.3 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF812 PF05667.11 KIK58424.1 - 0.15 10.9 5.4 0.19 10.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PKcGMP_CC PF16808.5 KIK58424.1 - 0.43 10.5 6.0 6 6.8 0.4 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK58424.1 - 0.51 10.7 7.0 1.3 9.4 3.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KIK58424.1 - 0.92 9.6 12.6 2.7 8.0 6.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KIK58424.1 - 6.9 7.2 10.3 0.99 9.9 4.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF745 PF05335.13 KIK58425.1 - 0.087 12.5 5.2 1.7 8.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 KIK58425.1 - 0.14 12.2 5.6 0.25 11.4 5.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ThiC-associated PF13667.6 KIK58429.1 - 0.1 12.4 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 ThiC-associated domain UCH_C PF18031.1 KIK58431.1 - 0.031 14.2 2.0 6.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases DDE_Tnp_4 PF13359.6 KIK58432.1 - 0.0013 18.4 0.0 0.075 12.7 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease C2-set PF05790.15 KIK58433.1 - 0.007 16.5 0.4 0.29 11.3 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin C2-set domain KDZ PF18758.1 KIK58434.1 - 5.1e-20 72.1 1.7 5.7e-20 71.9 1.7 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Plavaka PF18759.1 KIK58438.1 - 2.2e-11 43.6 0.1 3.4e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK58439.1 - 8.6e-33 113.9 0.2 1e-32 113.7 0.2 1.1 1 0 0 1 1 1 1 Plavaka transposase SRF-TF PF00319.18 KIK58445.1 - 4.5e-22 77.3 0.1 6.8e-22 76.7 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TPR_10 PF13374.6 KIK58446.1 - 2e-68 224.6 16.9 4.6e-14 51.8 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58446.1 - 3.9e-56 187.3 15.5 5.3e-17 61.9 0.5 4.8 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58446.1 - 6.3e-16 57.5 0.7 0.024 15.0 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58446.1 - 7e-15 55.2 7.0 3.3e-08 33.3 3.4 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KIK58446.1 - 1.5e-13 49.9 6.3 0.03 14.1 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58446.1 - 5.6e-13 47.9 7.8 0.058 13.5 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58446.1 - 3.2e-12 45.6 9.5 0.031 14.5 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58446.1 - 6.8e-11 41.4 10.5 0.003 17.5 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58446.1 - 1.1e-09 37.9 0.0 1.8 9.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK58446.1 - 3.8e-09 37.0 0.0 0.62 10.8 0.0 4.9 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58446.1 - 1.6e-07 31.7 0.0 1.1 9.8 0.0 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 KIK58446.1 - 2.9e-07 30.3 8.1 5.2 7.6 0.1 5.4 5 0 0 5 5 5 2 PPR repeat DUF1897 PF09005.10 KIK58446.1 - 2.3e-05 23.8 7.5 3.1 7.4 0.1 5.2 5 0 0 5 5 5 2 Domain of unknown function (DUF1897) DUF4919 PF16266.5 KIK58446.1 - 7.8e-05 22.7 0.3 8.3 6.3 0.0 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4919) SSI PF00720.17 KIK58446.1 - 0.00047 20.1 0.9 3.6 7.6 0.1 3.8 2 1 2 4 4 4 1 Subtilisin inhibitor-like RPN7 PF10602.9 KIK58446.1 - 0.00095 18.9 2.7 3.4 7.4 0.2 3.6 2 1 2 4 4 4 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 KIK58446.1 - 0.00096 19.8 2.1 52 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Meckelin PF09773.9 KIK58446.1 - 0.0012 17.0 0.3 3.3 5.7 0.1 3.0 1 1 2 3 3 3 2 Meckelin (Transmembrane protein 67) ECSCR PF15820.5 KIK58446.1 - 0.0036 17.1 0.0 39 4.1 0.0 4.4 1 1 4 5 5 5 0 Endothelial cell-specific chemotaxis regulator TPR_11 PF13414.6 KIK58446.1 - 0.006 16.2 4.3 9.4 6.0 0.0 4.5 5 0 0 5 5 5 0 TPR repeat PPR_2 PF13041.6 KIK58446.1 - 0.038 14.2 2.5 56 4.0 0.0 4.8 5 0 0 5 5 5 0 PPR repeat family EP400_N PF15790.5 KIK58446.1 - 0.27 10.0 6.8 11 4.7 0.1 3.7 1 1 4 5 5 5 0 E1A-binding protein p400, N-terminal DUF5569 PF17729.1 KIK58446.1 - 1.8 8.4 7.1 20 5.0 0.1 3.5 1 1 3 4 4 4 0 Family of unknown function (DUF5569) PPR_1 PF12854.7 KIK58446.1 - 9.3 6.1 19.6 51 3.7 0.1 5.9 5 1 0 5 5 5 0 PPR repeat FATC PF02260.20 KIK58446.1 - 9.6 6.1 6.2 1.5e+02 2.3 0.1 4.1 4 0 0 4 4 4 0 FATC domain HTH_23 PF13384.6 KIK58448.1 - 6.1e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KIK58448.1 - 1.3e-05 25.4 0.0 2.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 KIK58448.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KIK58448.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 KIK58448.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) TPR_10 PF13374.6 KIK58450.1 - 3.5e-70 230.1 5.1 4.1e-13 48.7 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58450.1 - 1.4e-68 227.1 16.3 3.4e-17 62.5 0.3 5.0 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58450.1 - 6.8e-18 63.7 0.5 0.032 14.6 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58450.1 - 5.4e-16 57.4 7.0 0.027 14.6 0.0 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58450.1 - 1.8e-14 53.8 19.5 1.7e-08 34.3 2.4 2.8 1 1 2 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 KIK58450.1 - 3e-14 52.0 6.6 0.08 13.2 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58450.1 - 3.9e-14 51.8 6.1 0.19 11.6 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58450.1 - 4.8e-14 51.3 9.0 0.26 11.4 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58450.1 - 2.2e-11 43.3 0.0 0.17 12.6 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58450.1 - 5e-08 33.3 0.9 0.57 10.7 0.0 4.9 1 1 4 5 5 5 3 Tetratricopeptide repeat PPR PF01535.20 KIK58450.1 - 1.4e-05 25.0 10.7 5.5 7.5 0.1 5.7 6 0 0 6 6 5 2 PPR repeat RPN7 PF10602.9 KIK58450.1 - 2.1e-05 24.3 4.7 3.3 7.4 0.2 4.8 2 2 2 5 5 5 3 26S proteasome subunit RPN7 TPR_16 PF13432.6 KIK58450.1 - 2.3e-05 25.0 0.0 2.5 8.8 0.0 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK58450.1 - 6.7e-05 23.4 1.8 2 9.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Elong_Iki1 PF10483.9 KIK58450.1 - 0.012 15.1 0.0 1.3 8.4 0.0 2.3 1 1 0 1 1 1 0 Elongator subunit Iki1 DUF1897 PF09005.10 KIK58450.1 - 0.12 11.9 0.7 24 4.5 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) PPR_1 PF12854.7 KIK58450.1 - 0.39 10.5 5.9 54 3.6 0.1 4.4 4 0 0 4 4 4 0 PPR repeat PPR_2 PF13041.6 KIK58450.1 - 0.69 10.2 3.8 2.3e+02 2.1 0.0 4.6 5 0 0 5 5 5 0 PPR repeat family Ysc84 PF04366.12 KIK58454.1 - 0.0063 16.3 0.0 0.0063 16.3 0.0 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator SRF-TF PF00319.18 KIK58454.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Ras PF00071.22 KIK58459.1 - 0.042 13.5 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Ras family TPR_10 PF13374.6 KIK58462.1 - 3.3e-15 55.4 0.6 1e-07 31.6 0.1 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58462.1 - 4.1e-13 49.4 0.1 4.8e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58462.1 - 3.8e-05 23.2 0.3 4.1e-05 23.1 0.3 1.0 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KIK58462.1 - 0.0013 18.7 0.1 0.99 9.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58462.1 - 0.003 17.3 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58462.1 - 0.0087 16.6 0.0 7.3 7.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58462.1 - 0.0087 16.2 0.3 1.4 9.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58462.1 - 0.03 14.4 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58462.1 - 0.036 14.5 0.1 0.91 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK58462.1 - 0.096 12.4 0.3 7.8 6.3 0.1 2.2 2 0 0 2 2 2 0 TPR repeat TPR_3 PF07720.12 KIK58462.1 - 0.13 12.3 0.1 9.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58463.1 - 3.8e-25 88.0 0.8 3e-15 56.3 0.2 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK58463.1 - 2.2e-23 81.4 1.1 9.1e-13 47.6 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58463.1 - 3e-07 30.4 0.1 0.02 15.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58463.1 - 9.2e-06 25.3 0.1 0.027 14.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58463.1 - 1.1e-05 25.2 0.3 0.13 12.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58463.1 - 1.1e-05 25.0 0.5 1.2e-05 24.9 0.5 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KIK58463.1 - 3.4e-05 23.6 0.2 0.0081 16.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58463.1 - 5.4e-05 22.9 0.3 0.26 11.4 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58463.1 - 0.0086 16.6 0.0 0.18 12.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4919 PF16266.5 KIK58463.1 - 0.011 15.7 0.1 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) TPR_19 PF14559.6 KIK58463.1 - 0.022 15.3 0.0 4.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK58463.1 - 0.031 14.0 0.2 2.1 8.0 0.0 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 PPR PF01535.20 KIK58463.1 - 0.042 14.1 0.1 4.3 7.8 0.0 2.3 2 0 0 2 2 2 0 PPR repeat S10_plectin PF03501.15 KIK58463.1 - 0.097 12.8 0.3 8.9 6.5 0.0 2.0 1 1 1 2 2 2 0 Plectin/S10 domain TPR_3 PF07720.12 KIK58463.1 - 0.15 12.1 0.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L18p PF00861.22 KIK58463.1 - 0.16 12.4 0.0 0.56 10.6 0.0 1.7 1 1 1 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RILP PF11461.8 KIK58463.1 - 0.99 9.7 5.6 1.5 9.1 1.8 2.3 2 1 0 2 2 2 0 Rab interacting lysosomal protein FATC PF02260.20 KIK58463.1 - 1.1 9.1 4.0 8.2 6.3 0.1 2.5 3 0 0 3 3 3 0 FATC domain TPR_10 PF13374.6 KIK58466.1 - 8.4e-72 235.3 3.9 5.5e-12 45.2 0.0 7.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58466.1 - 7.9e-69 227.9 19.0 2.6e-16 59.7 0.1 5.7 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58466.1 - 1.7e-19 70.4 8.1 1.5e-07 31.2 0.1 2.9 1 1 2 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 KIK58466.1 - 6.7e-15 54.0 8.6 0.014 15.3 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58466.1 - 3.3e-14 52.0 12.7 0.2 11.5 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58466.1 - 4.7e-14 51.3 14.3 0.055 13.6 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58466.1 - 1.3e-13 50.0 11.9 0.23 11.8 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58466.1 - 9.7e-13 47.6 0.5 0.26 11.8 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58466.1 - 1.4e-09 37.7 0.0 0.24 12.1 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58466.1 - 2.8e-09 37.3 1.8 0.69 10.5 0.1 6.0 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK58466.1 - 0.00029 21.4 0.0 16 6.2 0.1 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK58466.1 - 0.00043 20.9 6.1 34 5.6 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2577 PF10844.8 KIK58466.1 - 0.0071 16.5 2.7 3.4 8.0 0.2 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2577) TPR_11 PF13414.6 KIK58466.1 - 0.0092 15.6 12.7 5.3 6.8 0.0 5.9 7 0 0 7 7 7 1 TPR repeat TPR_20 PF14561.6 KIK58466.1 - 0.046 14.1 0.0 6.6 7.1 0.0 3.8 4 1 1 5 5 4 0 Tetratricopeptide repeat MCPVI PF02993.14 KIK58466.1 - 0.053 13.3 1.0 0.74 9.6 0.1 2.7 1 1 2 3 3 3 0 Minor capsid protein VI PPR PF01535.20 KIK58466.1 - 0.053 13.8 12.8 30 5.1 0.1 6.4 7 0 0 7 7 6 0 PPR repeat BOFC_N PF08977.10 KIK58466.1 - 0.082 12.9 0.0 19 5.4 0.0 4.1 5 0 0 5 5 5 0 Bypass of Forespore C, N terminal Alpha-mann_mid PF09261.11 KIK58466.1 - 0.083 13.0 0.2 0.43 10.8 0.0 2.4 1 1 1 2 2 2 0 Alpha mannosidase middle domain DUF1897 PF09005.10 KIK58466.1 - 0.086 12.3 5.2 3.9 7.0 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) TPR_6 PF13174.6 KIK58466.1 - 1.2 9.9 5.4 2.9e+02 2.5 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 KIK58466.1 - 1.8 9.3 8.5 54 4.5 0.1 5.2 5 2 0 5 5 5 0 Cytochrome b562 ABC_tran PF00005.27 KIK58469.1 - 2.5e-40 138.2 0.1 3.3e-24 85.9 0.1 2.6 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK58469.1 - 8.7e-39 133.8 37.9 6.2e-21 75.3 11.0 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK58469.1 - 2e-10 40.5 0.0 0.036 13.5 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIK58469.1 - 5e-06 26.2 0.0 0.098 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIK58469.1 - 8.3e-06 26.4 1.9 0.0012 19.3 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK58469.1 - 9e-06 25.3 0.6 0.044 13.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KIK58469.1 - 1.6e-05 24.2 0.0 0.011 14.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KIK58469.1 - 1.7e-05 25.3 0.1 0.087 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK58469.1 - 0.00011 22.1 8.2 0.064 13.1 0.5 4.0 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIK58469.1 - 0.00057 20.2 0.1 1.1 9.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK58469.1 - 0.0014 19.2 0.0 0.75 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK58469.1 - 0.0016 18.0 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK58469.1 - 0.0026 17.5 0.1 2 8.1 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein cobW PF02492.19 KIK58469.1 - 0.004 16.8 0.7 0.29 10.7 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 KIK58469.1 - 0.005 16.3 0.6 2.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Poxvirus A32 protein RsgA_GTPase PF03193.16 KIK58469.1 - 0.0068 16.3 0.1 3.9 7.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KIK58469.1 - 0.0078 16.3 3.0 0.11 12.6 0.5 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_11 PF13086.6 KIK58469.1 - 0.0084 15.9 0.0 0.023 14.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TrwB_AAD_bind PF10412.9 KIK58469.1 - 0.011 14.7 2.2 1.3 7.8 0.1 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KIK58469.1 - 0.013 15.5 2.0 0.38 10.9 0.1 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase ResIII PF04851.15 KIK58469.1 - 0.014 15.4 0.0 2.6 8.0 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Adeno_IVa2 PF02456.15 KIK58469.1 - 0.02 13.7 0.1 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 KIK58469.1 - 0.031 14.2 0.5 7.5 6.4 0.1 2.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KIK58469.1 - 0.033 13.9 0.0 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK58469.1 - 0.034 13.4 0.0 4.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KIK58469.1 - 0.062 13.7 0.0 2.5 8.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK58469.1 - 0.098 12.6 0.5 21 5.0 0.0 2.8 3 0 0 3 3 2 0 NTPase FtsK_SpoIIIE PF01580.18 KIK58469.1 - 0.13 11.6 0.1 18 4.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KIK58469.1 - 0.13 12.4 0.0 15 5.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK58469.1 - 0.15 12.1 0.3 27 4.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KIK58469.1 - 0.17 11.1 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) 60KD_IMP PF02096.20 KIK58469.1 - 1.1 9.2 5.6 0.34 10.8 2.0 2.1 2 0 0 2 2 1 0 60Kd inner membrane protein DUF4939 PF16297.5 KIK58471.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KIK58471.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon gag protein DNA_repr_REX1B PF14966.6 KIK58471.1 - 0.025 15.2 0.0 0.071 13.8 0.0 1.7 2 0 0 2 2 2 0 DNA repair REX1-B TPR_10 PF13374.6 KIK58473.1 - 3.1e-115 373.4 13.0 1.1e-11 44.1 0.0 11.0 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58473.1 - 2e-97 319.6 34.0 5e-15 55.5 0.3 9.1 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58473.1 - 3.1e-32 112.3 44.2 1.5e-09 37.7 3.3 4.7 1 1 5 6 6 6 6 MalT-like TPR region TPR_17 PF13431.6 KIK58473.1 - 2.8e-27 93.1 9.4 0.15 12.5 0.1 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58473.1 - 1.1e-23 81.3 24.2 0.017 15.2 0.1 10.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58473.1 - 6e-23 79.1 29.4 0.047 13.9 0.1 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58473.1 - 3.9e-21 73.9 24.2 0.05 13.4 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58473.1 - 1.7e-18 65.2 13.8 0.38 10.9 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58473.1 - 9.6e-15 53.6 0.0 0.73 10.6 0.0 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK58473.1 - 2.4e-14 53.7 0.0 1.2 9.9 0.0 8.5 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58473.1 - 1.2e-11 44.9 7.5 0.1 13.1 0.0 8.6 1 1 10 11 11 11 2 Tetratricopeptide repeat RPN7 PF10602.9 KIK58473.1 - 1e-07 31.9 14.3 0.7 9.6 0.1 6.8 2 2 4 8 8 8 5 26S proteasome subunit RPN7 PPR PF01535.20 KIK58473.1 - 1.5e-07 31.2 24.6 5 7.6 0.1 10.6 10 1 1 11 11 11 1 PPR repeat TPR_3 PF07720.12 KIK58473.1 - 4.2e-05 23.4 12.3 2.2 8.3 0.1 7.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK58473.1 - 0.00019 22.0 5.3 87 4.4 0.0 8.1 9 1 1 10 10 9 0 Tetratricopeptide repeat ATPgrasp_N PF18130.1 KIK58473.1 - 0.0013 19.2 2.4 28 5.4 0.0 5.5 6 0 0 6 6 6 0 ATP-grasp N-terminal domain EP400_N PF15790.5 KIK58473.1 - 0.0017 17.3 2.2 0.72 8.6 0.0 4.0 4 1 1 5 5 5 1 E1A-binding protein p400, N-terminal TPR_11 PF13414.6 KIK58473.1 - 0.0079 15.9 10.6 27 4.5 0.1 7.9 9 0 0 9 9 9 0 TPR repeat BOFC_N PF08977.10 KIK58473.1 - 0.012 15.5 0.0 12 6.0 0.0 4.5 5 0 0 5 5 4 0 Bypass of Forespore C, N terminal ADH_zinc_N PF00107.26 KIK58473.1 - 0.086 12.8 0.7 65 3.5 0.0 4.5 5 1 1 6 6 6 0 Zinc-binding dehydrogenase TPR_6 PF13174.6 KIK58473.1 - 0.1 13.3 3.8 3.2e+02 2.3 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4810 PF16068.5 KIK58473.1 - 0.28 11.8 6.2 50 4.5 0.0 5.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4810) Pterin_4a PF01329.19 KIK58473.1 - 2 8.6 11.4 25 5.1 0.1 5.6 5 3 3 8 8 7 0 Pterin 4 alpha carbinolamine dehydratase DED PF01335.21 KIK58473.1 - 2.5 8.4 8.1 1.8 8.9 0.1 4.3 3 3 0 3 3 3 0 Death effector domain TPR_10 PF13374.6 KIK58474.1 - 1.2e-97 317.5 19.1 1.9e-11 43.5 0.1 10.0 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58474.1 - 1.9e-95 313.2 49.1 5e-17 62.0 0.7 7.9 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58474.1 - 1e-22 81.0 21.0 1.6e-08 34.3 3.5 4.0 1 1 3 4 4 4 4 MalT-like TPR region TPR_2 PF07719.17 KIK58474.1 - 1.5e-18 65.3 24.9 0.011 15.8 0.1 8.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58474.1 - 1e-17 63.2 8.6 0.95 10.0 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58474.1 - 5e-17 60.6 17.3 0.042 13.9 0.1 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58474.1 - 6.4e-16 57.4 26.3 0.036 13.9 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58474.1 - 3.7e-13 48.5 24.4 0.21 11.9 0.2 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58474.1 - 1.4e-10 40.7 0.0 0.015 15.8 0.1 7.4 10 0 0 10 10 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK58474.1 - 2e-08 34.7 6.5 0.14 12.8 0.0 6.8 6 3 1 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58474.1 - 9.6e-05 22.8 14.1 1.7 9.2 0.1 6.8 3 3 5 8 8 8 1 Tetratricopeptide repeat RPN7 PF10602.9 KIK58474.1 - 0.00014 21.6 9.9 0.84 9.3 0.8 5.3 2 1 4 6 6 6 2 26S proteasome subunit RPN7 TPR_3 PF07720.12 KIK58474.1 - 0.0034 17.3 15.0 3.7 7.7 0.3 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 KIK58474.1 - 0.0062 16.7 16.2 79 3.8 0.0 8.0 8 1 0 8 8 8 0 PPR repeat DHDPS PF00701.22 KIK58474.1 - 0.013 14.3 10.3 0.73 8.5 0.1 5.4 1 1 5 7 7 7 0 Dihydrodipicolinate synthetase family HopA1 PF17914.1 KIK58474.1 - 0.052 13.3 1.7 60 3.3 0.1 4.3 4 1 1 5 5 5 0 HopA1 effector protein family TPR_14 PF13428.6 KIK58474.1 - 0.39 11.7 11.3 55 5.0 0.1 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Spore_YpjB PF09577.10 KIK58474.1 - 1.4 8.7 6.1 7.3 6.3 0.4 3.6 2 1 1 5 5 5 0 Sporulation protein YpjB (SpoYpjB) TPR_6 PF13174.6 KIK58474.1 - 2.7 8.8 8.7 26 5.7 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat EP400_N PF15790.5 KIK58474.1 - 3 6.6 5.9 23 3.7 0.1 3.7 2 1 3 5 5 5 0 E1A-binding protein p400, N-terminal DUF1040 PF06288.13 KIK58474.1 - 5.8 7.4 10.8 3 8.3 0.2 4.1 2 2 2 5 5 5 0 Protein of unknown function (DUF1040) ABC_tran PF00005.27 KIK58475.1 - 3.3e-13 50.3 0.0 4.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK58475.1 - 0.082 12.3 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain HLH PF00010.26 KIK58476.1 - 5.4e-18 64.7 0.3 3.7e-10 39.6 0.0 3.8 3 1 1 4 4 4 2 Helix-loop-helix DNA-binding domain TPR_10 PF13374.6 KIK58479.1 - 1.5e-85 279.1 10.8 4.2e-13 48.7 0.0 9.0 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58479.1 - 1e-65 217.9 18.8 5.1e-13 49.1 0.1 6.9 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58479.1 - 3.1e-17 61.6 6.2 0.055 13.9 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58479.1 - 1.4e-14 53.0 22.1 0.21 11.9 0.3 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58479.1 - 4.5e-14 52.6 10.6 1.6e-05 24.4 0.4 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 KIK58479.1 - 2.4e-13 49.3 20.8 0.1 12.5 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58479.1 - 1.7e-12 46.4 8.4 0.027 14.5 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 KIK58479.1 - 1.6e-09 37.5 0.0 3.6 8.5 0.0 6.4 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58479.1 - 1.7e-07 30.8 17.3 0.71 10.1 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat RPN7 PF10602.9 KIK58479.1 - 6.1e-07 29.3 8.7 0.011 15.4 0.0 5.1 1 1 4 6 6 6 2 26S proteasome subunit RPN7 TPR_19 PF14559.6 KIK58479.1 - 2e-05 25.0 4.9 1.5 9.4 0.0 6.5 1 1 7 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK58479.1 - 0.0003 21.3 0.3 30 5.8 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KIK58479.1 - 0.0017 18.4 25.6 1.1 9.7 0.1 7.8 8 0 0 8 8 8 1 PPR repeat TPR_16 PF13432.6 KIK58479.1 - 0.016 15.8 0.0 58 4.5 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1897 PF09005.10 KIK58479.1 - 0.017 14.6 1.0 30 4.2 0.0 4.7 6 0 0 6 6 6 0 Domain of unknown function (DUF1897) SSI PF00720.17 KIK58479.1 - 0.12 12.3 1.6 6.7 6.7 0.0 3.4 1 1 3 4 4 4 0 Subtilisin inhibitor-like IKBKB_SDD PF18397.1 KIK58479.1 - 0.21 10.9 4.1 29 3.8 0.0 4.5 3 2 2 5 5 5 0 IQBAL scaffold dimerization domain PPR_1 PF12854.7 KIK58479.1 - 0.44 10.3 13.5 25 4.7 0.2 6.7 7 0 0 7 7 7 0 PPR repeat Spore_YpjB PF09577.10 KIK58479.1 - 0.88 9.3 3.1 21 4.8 0.1 3.0 3 0 0 3 3 3 0 Sporulation protein YpjB (SpoYpjB) DUF1040 PF06288.13 KIK58479.1 - 5.8 7.4 9.5 4.2 7.8 0.4 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF1040) CxC1 PF18802.1 KIK58480.1 - 0.0011 19.1 0.2 0.0014 18.8 0.2 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIK58480.1 - 0.064 13.4 0.1 0.082 13.1 0.1 1.2 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK58481.1 - 6e-23 81.6 1.0 7.2e-23 81.4 1.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Retrotrans_gag PF03732.17 KIK58482.1 - 0.011 16.0 0.7 0.026 14.8 0.1 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 KIK58485.1 - 2e-05 24.6 0.1 2.8e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KIK58486.1 - 2.4e-05 24.5 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 KIK58487.1 - 0.00013 22.2 1.4 0.0033 17.7 0.0 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein RuvA_C PF07499.13 KIK58487.1 - 0.18 12.3 0.4 27 5.3 0.0 2.5 2 0 0 2 2 2 0 RuvA, C-terminal domain TPR_10 PF13374.6 KIK58488.1 - 1.4e-52 174.3 15.3 2.3e-14 52.7 0.0 8.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KIK58488.1 - 1.2e-43 147.2 5.1 1.7e-12 47.4 0.0 6.0 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58488.1 - 1.7e-10 40.3 4.5 0.0067 16.6 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK58488.1 - 1e-09 37.7 2.9 0.084 12.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58488.1 - 1.6e-08 34.3 2.4 0.0017 17.8 0.2 2.8 1 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KIK58488.1 - 3.4e-06 26.6 4.2 1.3 9.0 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK58488.1 - 0.00083 19.6 9.7 0.63 10.5 0.1 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK58488.1 - 0.004 17.6 0.6 26 5.4 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58488.1 - 0.014 15.5 2.0 25 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MCPVI PF02993.14 KIK58488.1 - 0.036 13.9 0.3 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Minor capsid protein VI WD40_alt PF14077.6 KIK58488.1 - 4.7 7.1 6.2 18 5.3 0.3 3.6 4 0 0 4 4 4 0 Alternative WD40 repeat motif Bac_DnaA_C PF08299.11 KIK58489.1 - 0.02 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix ABC_tran PF00005.27 KIK58490.1 - 1.3e-24 87.2 0.1 2.5e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIK58490.1 - 3.4e-06 26.9 5.0 5.3e-06 26.3 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF87 PF01935.17 KIK58490.1 - 0.0032 17.6 0.2 0.0089 16.1 0.2 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_25 PF13481.6 KIK58490.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIK58490.1 - 0.085 12.3 0.6 12 5.3 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KIK58490.1 - 0.096 12.4 0.1 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 KIK58490.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KIK58490.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK58490.1 - 0.14 11.9 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 KIK58491.1 - 0.056 13.1 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region WD40 PF00400.32 KIK58493.1 - 1.4e-121 392.8 40.8 1.8e-11 44.4 0.0 12.8 14 0 0 14 14 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58493.1 - 4.3e-39 132.7 6.1 0.0024 18.1 0.0 10.5 2 2 9 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK58493.1 - 3.3e-26 92.4 0.5 3.6e-05 23.7 0.0 5.3 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK58493.1 - 9.1e-14 51.5 4.2 1.9 7.8 0.0 8.9 6 2 3 9 9 9 4 WD40-like domain PD40 PF07676.12 KIK58493.1 - 1.4e-13 50.4 0.4 13 5.9 0.0 10.6 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK58493.1 - 5.3e-12 45.2 11.9 0.34 9.5 0.1 8.9 3 3 7 10 10 10 6 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK58493.1 - 1.2e-11 44.1 10.2 2.8 6.8 0.0 9.4 2 2 8 10 10 10 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK58493.1 - 9.1e-09 34.3 10.3 0.00024 19.7 0.3 4.6 1 1 2 3 3 3 3 Cytochrome D1 heme domain nos_propeller PF18764.1 KIK58493.1 - 2.9e-08 33.5 20.5 8.1 6.4 0.0 10.2 11 0 0 11 11 11 1 Nitrous oxide reductase propeller repeat potato_inhibit PF00280.18 KIK58493.1 - 8.3e-08 32.8 0.2 40 5.0 0.0 8.4 5 2 5 10 10 10 0 Potato inhibitor I family NHL PF01436.21 KIK58493.1 - 2.4e-06 27.3 18.5 33 4.7 0.0 10.6 11 0 0 11 11 11 0 NHL repeat Peptidase_S9_N PF02897.15 KIK58493.1 - 8.5e-05 21.5 0.9 0.46 9.2 0.1 5.2 3 2 2 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DsbC_N PF10411.9 KIK58493.1 - 0.0013 18.1 14.0 1.2e+02 2.3 0.0 9.5 11 0 0 11 11 11 0 Disulfide bond isomerase protein N-terminus zf-LYAR PF08790.11 KIK58493.1 - 0.02 14.8 0.2 2.6 8.1 0.1 3.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger MRJP PF03022.16 KIK58493.1 - 0.051 12.9 2.3 0.63 9.4 0.1 3.2 2 2 2 4 4 4 0 Major royal jelly protein DUF4019 PF13211.6 KIK58493.1 - 3.5 8.1 7.2 19 5.7 0.1 5.3 5 2 3 8 8 8 0 Protein of unknown function (DUF4019) Peptidase_S49_N PF08496.10 KIK58499.1 - 0.0012 18.9 0.2 0.0019 18.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal HMMR_N PF15905.5 KIK58499.1 - 0.0043 16.6 3.5 0.0058 16.2 3.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Lectin_N PF03954.14 KIK58499.1 - 0.0063 16.3 2.3 0.17 11.6 0.6 2.4 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Sec2p PF06428.11 KIK58499.1 - 0.058 13.4 5.7 0.037 14.0 2.9 1.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 KIK58499.1 - 0.07 12.0 4.1 0.097 11.5 4.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KIK58499.1 - 0.078 12.8 7.8 0.11 12.3 7.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PKcGMP_CC PF16808.5 KIK58499.1 - 0.12 12.3 5.3 5.7 6.9 0.3 2.7 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran_Xtn PF12848.7 KIK58499.1 - 0.18 11.8 1.3 0.34 11.0 1.3 1.4 1 0 0 1 1 1 0 ABC transporter MPS2 PF17060.5 KIK58499.1 - 0.27 10.5 2.8 0.41 9.9 2.8 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Csm1_N PF18504.1 KIK58499.1 - 1.1 9.7 5.0 32 5.0 2.3 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Med9 PF07544.13 KIK58499.1 - 1.8 8.7 5.0 2.2 8.4 0.7 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 KIK58499.1 - 5.3 7.1 10.3 17 5.5 5.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Retrotrans_gag PF03732.17 KIK58501.1 - 8.1e-07 29.2 0.0 1.9e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK58501.1 - 5.7e-05 23.0 3.8 0.00011 22.1 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Isy1 PF06246.12 KIK58503.1 - 0.042 13.4 0.7 0.05 13.2 0.7 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Retrotrans_gag PF03732.17 KIK58504.1 - 0.0085 16.4 0.0 0.0097 16.2 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein Cauli_VI PF01693.16 KIK58505.1 - 0.00015 22.0 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin FOG_N PF15888.5 KIK58505.1 - 0.03 14.7 0.1 3.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Folded gastrulation N-terminus Phage_integrase PF00589.22 KIK58508.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 Phage integrase family RVT_3 PF13456.6 KIK58509.1 - 0.037 13.8 0.0 0.054 13.3 0.0 1.4 1 1 0 1 1 1 0 Reverse transcriptase-like MFS_1 PF07690.16 KIK58511.1 - 7e-27 94.3 33.1 9.5e-27 93.8 33.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 KIK58513.1 - 6.1e-144 463.6 55.8 2.2e-11 44.1 0.2 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58513.1 - 3.3e-41 139.5 12.6 0.00064 20.0 0.0 13.3 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK58513.1 - 3.1e-19 69.6 1.1 0.0023 17.9 0.0 6.5 1 1 7 8 8 8 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK58513.1 - 3.9e-14 52.2 17.2 1.4 7.5 0.0 10.7 5 3 6 11 11 11 7 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK58513.1 - 1.3e-13 51.0 4.6 4.8 6.4 0.0 10.4 8 3 2 11 11 11 3 WD40-like domain Ge1_WD40 PF16529.5 KIK58513.1 - 1.2e-12 47.5 13.1 0.17 10.8 0.0 10.7 1 1 11 13 13 13 3 WD40 region of Ge1, enhancer of mRNA-decapping protein HARP PF07443.13 KIK58513.1 - 2.9e-07 30.0 0.1 1.3 8.7 0.0 7.1 7 0 0 7 7 7 1 HepA-related protein (HARP) SdiA-regulated PF06977.11 KIK58513.1 - 2.8e-06 26.7 0.0 1.5 8.0 0.0 5.5 3 1 2 5 5 5 1 SdiA-regulated PD40 PF07676.12 KIK58513.1 - 9.4e-06 25.4 19.2 11 6.0 0.0 10.1 11 0 0 11 11 10 1 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK58513.1 - 0.0002 21.2 20.5 7.3 6.6 0.0 9.7 11 0 0 11 11 11 1 Nitrous oxide reductase propeller repeat IKI3 PF04762.12 KIK58513.1 - 0.00087 17.4 8.2 0.016 13.2 0.8 2.8 2 2 0 2 2 2 2 IKI3 family COPI_C PF06957.11 KIK58513.1 - 0.0029 16.4 0.0 2.1 7.0 0.0 4.3 4 2 1 5 5 5 1 Coatomer (COPI) alpha subunit C-terminus TFIIIC_delta PF12657.7 KIK58513.1 - 0.0054 16.7 5.9 0.23 11.4 0.0 3.7 3 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term AsnC_trans_reg PF01037.21 KIK58513.1 - 0.034 14.1 0.6 47 4.1 0.0 5.7 8 0 0 8 8 8 0 Lrp/AsnC ligand binding domain DUF3648 PF12364.8 KIK58513.1 - 7.3 6.8 6.3 5.6 7.2 0.6 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3648) SIP1 PF04938.12 KIK58515.1 - 0.19 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Hydrophobin PF01185.18 KIK58516.1 - 4.3e-24 84.9 8.5 5e-24 84.7 8.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 KIK58516.1 - 0.058 14.1 5.8 0.78 10.5 0.5 2.6 3 0 0 3 3 3 0 Ion channel inhibitory toxin Defensin_beta PF00711.19 KIK58516.1 - 4.3 7.4 11.5 0.95 9.5 1.8 2.3 2 0 0 2 2 2 0 Beta defensin RVT_1 PF00078.27 KIK58517.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrophobin PF01185.18 KIK58519.1 - 6.1e-16 58.8 1.6 7.7e-16 58.5 1.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin WD40 PF00400.32 KIK58520.1 - 4.3e-27 93.8 0.4 5.1e-09 36.6 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.11 KIK58520.1 - 8.7e-12 45.3 0.0 3.5e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KIK58520.1 - 3.1e-08 33.8 0.0 0.046 14.0 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK58520.1 - 1.3e-05 24.0 0.8 0.044 12.4 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK58520.1 - 6.9e-05 22.7 0.0 0.44 10.5 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK58520.1 - 0.00038 19.9 0.0 0.69 9.2 0.0 2.7 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KIK58520.1 - 0.011 14.7 0.1 0.63 8.9 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DsbC_N PF10411.9 KIK58520.1 - 0.018 14.5 0.2 8.8 5.9 0.0 3.2 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus nos_propeller PF18764.1 KIK58520.1 - 0.024 14.5 0.1 8.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Cytochrom_D1 PF02239.16 KIK58520.1 - 0.037 12.6 0.0 0.18 10.3 0.0 1.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain NHL PF01436.21 KIK58520.1 - 0.075 13.1 0.4 40 4.5 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Big_4 PF07532.11 KIK58520.1 - 1.3 8.8 4.1 18 5.2 0.0 3.4 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 4) Hydrophobin PF01185.18 KIK58521.1 - 1.1e-22 80.4 6.9 1.5e-22 80.0 6.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin ELP6 PF09807.9 KIK58521.1 - 0.24 10.8 0.3 0.29 10.5 0.3 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 Penaeidin PF05927.11 KIK58521.1 - 0.49 11.2 7.5 0.41 11.4 2.1 2.2 2 0 0 2 2 2 0 Penaeidin Pkinase_Tyr PF07714.17 KIK58522.1 - 0.0038 16.6 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK58522.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KIK58523.1 - 3.2e-24 85.6 0.0 4.9e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK58523.1 - 1.8e-22 80.0 0.0 2.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FmdA_AmdA PF03069.15 KIK58524.1 - 4.9e-61 206.6 0.0 8.2e-37 126.9 0.1 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family G-alpha PF00503.20 KIK58525.1 - 6.8e-95 318.2 1.0 8.3e-95 317.9 1.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK58525.1 - 1.5e-11 44.0 0.7 1.4e-06 27.9 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 KIK58525.1 - 0.0062 16.8 0.0 5.2 7.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Phage_cap_E PF03864.15 KIK58525.1 - 0.0087 15.3 0.6 0.015 14.5 0.6 1.3 1 0 0 1 1 1 1 Phage major capsid protein E AAA_29 PF13555.6 KIK58525.1 - 0.011 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KIK58525.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ank_4 PF13637.6 KIK58526.1 - 1.8e-08 34.7 0.1 0.086 13.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK58526.1 - 1.4e-05 25.3 0.3 0.013 16.0 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KIK58526.1 - 3.6e-05 24.3 0.0 5.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK58526.1 - 3.9e-05 23.7 0.1 0.43 11.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK58526.1 - 0.00027 21.2 0.3 7.1 7.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) NFACT-C PF11923.8 KIK58527.1 - 0.079 12.9 0.0 23 5.0 0.0 3.5 4 0 0 4 4 4 0 NFACT protein C-terminal domain GMC_oxred_N PF00732.19 KIK58528.1 - 1.2e-64 218.6 0.0 1.8e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK58528.1 - 5.2e-35 121.1 0.0 9.7e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK58528.1 - 2.7e-06 26.7 0.1 4.3e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KIK58528.1 - 0.0015 17.8 0.1 0.0037 16.5 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIK58528.1 - 0.0017 17.5 1.3 0.016 14.3 1.3 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK58528.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK58528.1 - 0.036 13.1 0.1 0.69 8.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KIK58528.1 - 0.053 12.2 0.4 0.088 11.5 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FNIP_M PF14637.6 KIK58529.1 - 0.085 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Hydrophobin PF01185.18 KIK58530.1 - 2e-24 86.0 8.2 2.2e-24 85.9 8.2 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK58534.1 - 2.4e-23 82.6 9.7 3.2e-23 82.1 9.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin ECSCR PF15820.5 KIK58536.1 - 0.15 11.9 0.4 0.37 10.7 0.4 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Cortexin PF11057.8 KIK58536.1 - 2.5 8.0 5.3 0.74 9.7 1.4 2.1 2 0 0 2 2 2 0 Cortexin of kidney DUF3516 PF12029.8 KIK58537.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Brr6_like_C_C PF10104.9 KIK58539.1 - 0.0094 15.7 0.1 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain WBP-1 PF11669.8 KIK58539.1 - 0.053 14.2 0.1 6.6 7.4 0.0 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 CCB1 PF12046.8 KIK58539.1 - 0.058 12.7 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B PepSY_TM PF03929.16 KIK58539.1 - 0.07 12.8 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 PepSY-associated TM region RicinB_lectin_2 PF14200.6 KIK58543.1 - 9.3e-11 42.3 0.0 3.2e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like IL31 PF15209.6 KIK58544.1 - 0.065 13.0 0.3 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Interleukin 31 Tup_N PF08581.10 KIK58544.1 - 0.84 10.0 5.6 21 5.5 0.2 3.5 2 1 0 2 2 2 0 Tup N-terminal CD34_antigen PF06365.12 KIK58545.1 - 0.034 13.7 0.3 0.098 12.2 0.2 1.9 1 1 0 1 1 1 0 CD34/Podocalyxin family Baculo_PEP_C PF04513.12 KIK58546.1 - 0.00038 20.5 0.1 0.75 9.8 0.1 2.6 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus PhaP_Bmeg PF09602.10 KIK58546.1 - 0.019 14.9 2.1 0.076 12.9 0.2 2.6 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CdvA PF18822.1 KIK58546.1 - 0.054 13.3 2.6 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DUF2730 PF10805.8 KIK58546.1 - 0.061 13.4 0.0 0.3 11.2 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF883 PF05957.13 KIK58546.1 - 0.062 13.9 4.7 2.8 8.6 0.4 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SKA2 PF16740.5 KIK58546.1 - 0.32 10.8 3.0 0.7 9.7 0.2 2.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 IMD PF08397.11 KIK58546.1 - 0.4 10.0 4.5 0.17 11.3 0.2 2.3 2 1 1 3 3 3 0 IRSp53/MIM homology domain Filament PF00038.21 KIK58546.1 - 0.76 9.3 8.8 0.13 11.8 0.3 2.9 2 2 0 2 2 2 0 Intermediate filament protein WXG100 PF06013.12 KIK58546.1 - 0.92 9.8 4.4 22 5.4 0.3 4.1 3 1 2 5 5 4 0 Proteins of 100 residues with WXG FlxA PF14282.6 KIK58546.1 - 1.1 9.3 5.0 6.7 6.8 0.0 3.2 4 0 0 4 4 4 0 FlxA-like protein TipAS PF07739.13 KIK58546.1 - 1.9 9.0 6.1 0.73 10.4 0.9 2.8 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain DUF4795 PF16043.5 KIK58546.1 - 2.9 7.5 6.7 22 4.6 5.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) RIO1 PF01163.22 KIK58549.1 - 1.3e-05 24.9 0.1 1.6e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KIK58549.1 - 6.7e-05 22.4 0.4 7.8e-05 22.2 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KIK58549.1 - 0.00068 19.3 0.1 0.00079 19.1 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIK58549.1 - 0.0034 17.3 0.6 0.0034 17.3 0.6 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK58549.1 - 0.0039 16.6 2.6 0.0051 16.2 2.6 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pentapeptide_4 PF13599.6 KIK58549.1 - 0.048 13.8 0.3 1.3 9.2 0.4 2.1 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Pkinase_Tyr PF07714.17 KIK58549.1 - 0.077 12.3 0.2 0.087 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF5334 PF17268.2 KIK58549.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5334) DUF536 PF04394.14 KIK58550.1 - 0.011 15.6 5.4 1.6 8.7 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF536 DUF2730 PF10805.8 KIK58551.1 - 0.0079 16.3 3.3 0.018 15.1 0.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2730) DUF2312 PF10073.9 KIK58551.1 - 0.073 12.7 1.9 0.81 9.4 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) RNA_polI_A14 PF08203.11 KIK58551.1 - 0.24 12.1 1.1 1.1 10.1 0.1 2.6 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 V_ATPase_I PF01496.19 KIK58551.1 - 1.7 6.5 9.1 7.5 4.3 9.1 2.1 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2605 PF10792.9 KIK58551.1 - 1.8 8.5 5.7 6.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) zf-C4H2 PF10146.9 KIK58551.1 - 3 8.1 6.1 4.5 7.5 0.4 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein NPV_P10 PF05531.12 KIK58551.1 - 3.5 8.1 12.8 1.9 9.0 0.9 4.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF5320 PF17253.2 KIK58551.1 - 4.8 8.3 5.1 50 5.0 0.3 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5320) SlyX PF04102.12 KIK58551.1 - 6.5 7.5 9.5 32 5.2 0.5 4.3 4 1 0 4 4 4 0 SlyX RPW8 PF05659.11 KIK58551.1 - 7.4 6.3 9.9 8.5 6.1 0.0 3.4 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Thaumatin PF00314.17 KIK58552.1 - 4.1e-72 242.3 15.5 4.7e-72 242.1 15.5 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK58552.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-1,3-glucanase PQQ PF01011.21 KIK58552.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat SR-25 PF10500.9 KIK58553.1 - 0.0038 16.9 1.5 0.0041 16.8 1.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Heliorhodopsin PF18761.1 KIK58554.1 - 0.00079 18.8 2.5 0.0031 16.9 0.6 2.1 2 0 0 2 2 2 1 Heliorhodopsin DUF1345 PF07077.11 KIK58554.1 - 0.69 9.6 7.1 1.5 8.5 0.2 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1345) Pro_isomerase PF00160.21 KIK58556.1 - 1.8e-45 155.1 0.1 2e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SnoaL_2 PF12680.7 KIK58558.1 - 0.079 13.6 0.7 0.47 11.1 0.7 1.9 1 1 0 1 1 1 0 SnoaL-like domain zf-MYND PF01753.18 KIK58560.1 - 1.4e-07 31.5 18.2 3.3e-07 30.3 18.2 1.6 1 0 0 1 1 1 1 MYND finger DUF3824 PF12868.7 KIK58560.1 - 0.13 12.9 0.5 0.28 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Pkinase_Tyr PF07714.17 KIK58561.1 - 9e-35 120.2 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK58561.1 - 1.6e-29 103.1 0.0 2.6e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK58561.1 - 0.019 14.9 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK58563.1 - 3.6e-39 134.6 0.0 4.4e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK58563.1 - 2.5e-29 102.5 0.0 3.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK58563.1 - 0.0043 17.0 0.2 0.016 15.1 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK58563.1 - 0.045 13.0 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.25 KIK58564.1 - 6.7e-22 77.9 0.0 1.8e-21 76.5 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK58564.1 - 1.6e-16 60.6 0.1 9.6e-16 58.0 0.1 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KIK58564.1 - 0.0032 17.4 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1786 PF08735.10 KIK58564.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Nuc_N PF14448.6 KIK58564.1 - 0.029 14.2 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 Nuclease N terminal TFIID_NTD2 PF04494.15 KIK58564.1 - 0.2 11.9 0.0 3.9 7.7 0.0 2.5 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain CAP PF00188.26 KIK58565.1 - 1.2e-20 74.6 1.4 1.5e-20 74.3 1.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family adh_short PF00106.25 KIK58566.1 - 4.3e-26 91.6 0.0 6.8e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK58566.1 - 2.5e-23 82.9 0.0 3.5e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK58566.1 - 7.6e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 KIK58566.1 - 0.0074 16.2 0.1 0.024 14.5 0.0 1.9 2 1 0 2 2 2 1 YjeF-related protein N-terminus NmrA PF05368.13 KIK58566.1 - 0.033 13.8 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family Pkinase PF00069.25 KIK58567.1 - 7.5e-30 104.2 0.0 3.9e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK58567.1 - 5.3e-08 32.4 0.5 8.8e-06 25.2 0.0 2.6 3 1 0 3 3 3 2 Protein tyrosine kinase Sacchrp_dh_NADP PF03435.18 KIK58568.1 - 1.2e-17 64.4 0.1 2.3e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KIK58568.1 - 3.1e-05 24.4 0.1 0.00014 22.3 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KIK58568.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIK58568.1 - 0.0046 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK58568.1 - 0.0049 16.4 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 KIK58568.1 - 0.0096 16.6 0.1 0.034 14.8 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase MULE PF10551.9 KIK58569.1 - 0.0045 17.4 0.0 0.0096 16.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FYRC PF05965.14 KIK58570.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus WD40 PF00400.32 KIK58572.1 - 5.6e-144 463.7 31.4 6e-11 42.7 0.0 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58572.1 - 3.8e-40 136.1 14.7 0.011 16.0 0.0 13.4 1 1 11 13 13 13 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK58572.1 - 2e-21 76.7 6.1 0.00022 21.2 0.0 6.8 1 1 7 8 8 8 7 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK58572.1 - 2.8e-18 65.9 17.5 0.35 9.4 0.0 12.3 4 3 8 14 14 14 8 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK58572.1 - 1.2e-16 61.0 3.9 1.1 8.6 0.0 12.2 9 3 4 13 13 13 3 WD40-like domain PD40 PF07676.12 KIK58572.1 - 1.4e-13 50.3 0.3 30 4.7 0.0 12.8 14 0 0 14 14 14 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK58572.1 - 1.7e-12 47.0 19.3 7.6 6.5 0.0 12.2 12 1 1 13 13 12 1 Nitrous oxide reductase propeller repeat Ge1_WD40 PF16529.5 KIK58572.1 - 1.6e-08 33.9 7.9 6.9 5.5 0.0 10.6 2 1 12 14 14 14 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DsbC_N PF10411.9 KIK58572.1 - 1.6e-07 30.6 11.4 51 3.4 0.0 12.5 14 0 0 14 14 14 0 Disulfide bond isomerase protein N-terminus NHL PF01436.21 KIK58572.1 - 0.00052 19.9 11.4 88 3.4 0.0 10.1 12 0 0 12 12 12 0 NHL repeat Lipase_2 PF01674.18 KIK58572.1 - 0.0039 16.7 0.1 38 3.7 0.0 5.5 5 2 3 8 8 8 0 Lipase (class 2) Colicin_D PF11429.8 KIK58572.1 - 0.023 15.2 6.7 1.5 9.4 0.1 5.4 6 1 1 7 7 7 0 Colicin D NACHT PF05729.12 KIK58572.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Phi29_Phage_SSB PF17427.2 KIK58572.1 - 0.12 12.6 3.2 10 6.3 0.1 5.4 6 2 0 6 6 6 0 Phage Single-stranded DNA-binding protein DUF5122 PF17164.4 KIK58572.1 - 0.27 11.6 18.9 1.5e+02 2.8 0.0 9.6 12 0 0 12 12 11 0 Domain of unknown function (DUF5122) beta-propeller Cuticle_4 PF15955.5 KIK58572.1 - 0.37 11.5 5.5 5.6e+02 1.3 0.0 6.8 9 0 0 9 9 9 0 Cuticle protein Phage_sheath_1 PF04984.14 KIK58572.1 - 0.78 9.6 4.6 1.7e+02 1.9 0.0 6.0 6 1 1 7 7 7 0 Phage tail sheath protein subtilisin-like domain RPE65 PF03055.15 KIK58575.1 - 6.2e-17 61.9 0.0 6.9e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sugar_tr PF00083.24 KIK58576.1 - 1.2e-113 380.4 22.8 1.4e-113 380.2 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK58576.1 - 1.3e-20 73.7 30.0 1.3e-20 73.7 30.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RicinB_lectin_2 PF14200.6 KIK58577.1 - 1.3e-08 35.5 16.5 2e-08 34.8 4.4 2.5 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SASP PF00269.20 KIK58578.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type Toxin_38 PF14866.6 KIK58579.1 - 0.0042 17.3 0.1 0.007 16.6 0.1 1.3 1 0 0 1 1 1 1 Potassium channel toxin Sporozoite_P67 PF05642.11 KIK58579.1 - 3 5.8 18.1 3.5 5.6 18.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2HC5 PF06221.13 KIK58583.1 - 0.065 13.2 0.3 0.065 13.2 0.3 1.8 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 KIK58583.1 - 0.19 11.7 4.7 5.9 7.0 0.4 2.6 1 1 1 2 2 2 0 Double zinc ribbon Alpha_kinase PF02816.18 KIK58584.1 - 1.5e-08 35.0 0.1 1.7e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 Alpha-kinase family DDE_3 PF13358.6 KIK58585.1 - 6.1e-05 22.8 0.0 7.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Bunya_G2 PF03563.13 KIK58586.1 - 0.059 12.6 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DUF4519 PF15012.6 KIK58586.1 - 4.5 7.5 6.2 9 6.6 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) zf-RING_2 PF13639.6 KIK58587.1 - 3.8e-08 33.5 9.4 6e-08 32.9 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK58587.1 - 1.6e-07 31.0 5.8 2.5e-07 30.5 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK58587.1 - 9e-06 25.5 7.0 1.4e-05 24.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK58587.1 - 2e-05 24.3 9.7 3.4e-05 23.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK58587.1 - 0.0013 18.7 5.5 0.0025 17.8 5.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK58587.1 - 0.012 15.4 7.3 0.025 14.5 7.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK58587.1 - 0.019 14.9 6.2 0.031 14.2 6.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KIK58587.1 - 0.18 11.5 7.3 0.39 10.5 7.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Rad50_zn_hook PF04423.14 KIK58587.1 - 0.41 10.5 1.6 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 KIK58587.1 - 0.59 10.5 5.2 1.4 9.3 5.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KIK58587.1 - 2.8 7.7 4.9 5.6 6.7 4.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger Homeodomain PF00046.29 KIK58588.1 - 5.9e-06 26.0 1.3 1.1e-05 25.2 1.3 1.5 1 0 0 1 1 1 1 Homeodomain zf_ZIC PF18366.1 KIK58593.1 - 5.4e-05 23.2 0.4 0.00088 19.3 0.1 2.3 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 KIK58593.1 - 0.00048 20.4 4.5 0.00074 19.8 4.5 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KIK58593.1 - 0.00091 19.6 13.2 0.11 13.0 0.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK58593.1 - 0.0029 18.3 15.6 0.12 13.3 1.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger NTF2 PF02136.20 KIK58593.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain FOXP-CC PF16159.5 KIK58593.1 - 0.26 11.9 8.6 1.7 9.3 2.1 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain RSS_P20 PF11757.8 KIK58595.1 - 0.004 17.6 0.1 0.0058 17.0 0.1 1.3 1 0 0 1 1 1 1 Suppressor of RNA silencing P21-like N-terminal domain HemY_N PF07219.13 KIK58599.1 - 1.9 8.7 14.2 0.051 13.8 5.4 2.9 3 1 1 4 4 4 0 HemY protein N-terminus STE3 PF02076.15 KIK58599.1 - 4.7 6.3 14.5 0.032 13.4 4.3 2.1 2 1 0 2 2 2 0 Pheromone A receptor DUF3810 PF12725.7 KIK58599.1 - 7.4 5.8 7.2 1.1 8.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Tad PF13400.6 KIK58601.1 - 0.046 14.0 0.5 0.046 14.0 0.5 3.1 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like HemY_N PF07219.13 KIK58601.1 - 0.16 12.2 1.9 0.75 10.0 0.4 2.6 2 0 0 2 2 2 0 HemY protein N-terminus Ninjurin PF04923.12 KIK58601.1 - 1.3 9.0 4.4 0.88 9.5 2.2 1.8 2 0 0 2 2 2 0 Ninjurin DUF5134 PF17197.4 KIK58601.1 - 5.8 6.8 6.4 14 5.6 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) GWT1 PF06423.12 KIK58602.1 - 0.015 15.4 0.9 0.082 13.0 0.2 2.4 1 1 1 2 2 2 0 GWT1 DUF1345 PF07077.11 KIK58603.1 - 0.18 11.5 6.8 0.43 10.3 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) Wzy_C PF04932.15 KIK58603.1 - 0.35 10.5 7.6 0.18 11.4 0.4 2.7 2 1 0 2 2 2 0 O-Antigen ligase GWT1 PF06423.12 KIK58603.1 - 0.6 10.2 7.0 5.5 7.1 4.5 2.8 1 1 1 2 2 2 0 GWT1 DUF4293 PF14126.6 KIK58603.1 - 0.87 9.8 11.4 19 5.5 11.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Frizzled PF01534.17 KIK58603.1 - 0.92 8.5 13.2 0.63 9.0 8.3 2.4 2 1 1 3 3 3 0 Frizzled/Smoothened family membrane region DUF1218 PF06749.12 KIK58603.1 - 3.2 8.3 14.0 1 9.9 1.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) ATP-synt_I PF03899.15 KIK58603.1 - 5.1 7.5 18.6 0.19 12.1 4.2 3.3 2 1 1 3 3 3 0 ATP synthase I chain OST3_OST6 PF04756.13 KIK58603.1 - 5.9 6.1 6.9 1.5 8.1 0.3 2.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Pkinase_fungal PF17667.1 KIK58604.1 - 1.1e-37 129.8 0.0 6.6e-33 114.1 0.0 2.6 1 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK58604.1 - 3.5e-06 26.6 0.5 4.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KIK58604.1 - 0.0034 17.3 0.1 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2605 PF10792.9 KIK58604.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) PHC2_SAM_assoc PF16616.5 KIK58604.1 - 3 8.7 8.7 5.8 7.8 8.7 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Sugar_tr PF00083.24 KIK58606.1 - 4.9e-79 266.3 15.3 6e-79 266.0 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK58606.1 - 3.7e-29 101.8 28.0 3.7e-29 101.8 28.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M28 PF04389.17 KIK58607.1 - 2e-27 96.1 2.0 1.3e-26 93.5 2.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK58607.1 - 4.6e-08 33.0 0.1 7.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KIK58607.1 - 0.00063 18.9 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Phosphoesterase PF04185.14 KIK58607.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoesterase family F-box PF00646.33 KIK58609.1 - 1.8e-07 30.8 0.1 3.7e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK58609.1 - 5e-07 29.5 0.2 9.5e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK58609.1 - 0.0024 17.8 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 F-box COesterase PF00135.28 KIK58610.1 - 8.7e-85 285.5 0.0 1.2e-84 285.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK58610.1 - 0.00017 21.2 0.1 0.00028 20.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIK58610.1 - 0.03 14.2 0.0 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold 2OG-FeII_Oxy_2 PF13532.6 KIK58611.1 - 6.9e-29 101.4 0.1 8.6e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase_fungal PF17667.1 KIK58613.1 - 3.7e-39 134.7 0.0 1.7e-33 116.0 0.0 2.7 1 1 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK58613.1 - 1.2e-06 28.1 0.6 1.3e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KIK58613.1 - 0.0041 17.1 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK58613.1 - 0.12 11.6 0.3 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase MAGE_N PF12440.8 KIK58613.1 - 2.2 9.0 5.7 3.9 8.2 5.7 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Acyltransferase PF01553.21 KIK58616.1 - 1.5e-15 57.0 0.0 1.2e-06 28.2 0.0 2.8 3 0 0 3 3 3 2 Acyltransferase Oleosin PF01277.17 KIK58616.1 - 0.16 11.7 5.0 0.036 13.8 1.2 1.9 2 0 0 2 2 2 0 Oleosin DPBB_1 PF03330.18 KIK58617.1 - 1.7e-07 31.4 0.0 1.2e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIK58617.1 - 0.00025 20.9 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Barwin family DUF35_N PF12172.8 KIK58617.1 - 0.029 14.2 2.2 0.22 11.4 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CoA_transf_3 PF02515.17 KIK58619.1 - 1.7e-106 356.5 0.0 2e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III ABM PF03992.16 KIK58620.1 - 0.0013 18.8 0.1 0.24 11.5 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 KIK58620.1 - 0.039 14.2 0.2 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 DUF1479 PF07350.12 KIK58621.1 - 4.7e-145 483.5 0.0 5.6e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Coleoptericin PF06286.11 KIK58621.1 - 0.054 13.6 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Coleoptericin DDE_3 PF13358.6 KIK58622.1 - 0.00049 19.9 0.1 0.00088 19.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease NACHT PF05729.12 KIK58623.1 - 3.9e-06 26.9 0.1 5.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KIK58623.1 - 0.038 13.2 0.1 0.051 12.8 0.1 1.2 1 0 0 1 1 1 0 KAP family P-loop domain FliS PF02561.14 KIK58623.1 - 0.072 13.4 0.1 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliS Hamartin PF04388.12 KIK58624.1 - 1.7 7.2 8.4 2.1 6.9 8.4 1.2 1 0 0 1 1 1 0 Hamartin protein RTA1 PF04479.13 KIK58626.1 - 3.5e-19 69.3 0.0 3.3e-13 49.7 0.0 3.0 2 1 0 2 2 2 2 RTA1 like protein RTA1 PF04479.13 KIK58627.1 - 1.1e-61 208.0 1.7 1.1e-61 208.0 1.7 1.4 2 0 0 2 2 2 1 RTA1 like protein F-box-like PF12937.7 KIK58628.1 - 0.0015 18.4 0.1 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like Lipoprotein_2 PF00921.17 KIK58630.1 - 0.00022 20.9 0.0 0.00039 20.1 0.0 1.4 2 0 0 2 2 2 1 Borrelia lipoprotein DLH PF01738.18 KIK58632.1 - 9.7e-17 61.2 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Ni_hydr_CYTB PF01292.20 KIK58633.1 - 0.095 12.3 0.4 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 NACHT PF05729.12 KIK58634.1 - 1.3e-09 38.2 4.4 1.7e-09 37.8 0.4 3.0 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KIK58634.1 - 5.6e-08 33.4 0.1 2e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KIK58634.1 - 0.00035 19.9 6.9 0.043 13.1 0.0 2.9 2 1 0 3 3 3 2 KAP family P-loop domain NB-ARC PF00931.22 KIK58634.1 - 0.0012 18.1 1.0 0.0074 15.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KIK58634.1 - 0.0021 18.3 0.1 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK58634.1 - 0.0045 17.4 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KIK58634.1 - 0.032 14.7 0.2 0.5 10.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KIK58634.1 - 0.047 13.6 0.0 0.28 11.1 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KIK58634.1 - 0.05 13.3 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 KIK58634.1 - 0.08 12.8 0.1 0.48 10.3 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 KIK58634.1 - 0.094 12.8 0.0 2.5 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain T3SS_needle_E PF08988.10 KIK58634.1 - 0.16 12.1 0.7 4.9 7.4 0.1 2.8 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Latarcin PF10279.9 KIK58634.1 - 0.19 12.2 2.9 12 6.4 0.2 2.7 2 0 0 2 2 2 0 Latarcin precursor p450 PF00067.22 KIK58635.1 - 3.9e-54 184.1 0.0 4.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDP-OH_P_transf PF01066.21 KIK58636.1 - 2.5e-18 66.6 0.0 2.5e-18 66.6 0.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1708 PF08101.11 KIK58636.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) p450 PF00067.22 KIK58637.1 - 1.3e-57 195.6 0.0 1.6e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK58638.1 - 4.7e-12 45.4 0.0 5.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDP-OH_P_transf PF01066.21 KIK58639.1 - 1.2e-10 42.0 0.0 1.2e-10 42.0 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_79C PF16862.5 KIK58642.1 - 1.6e-18 67.5 3.5 6.6e-18 65.5 0.2 2.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Phage_holin_5_2 PF16079.5 KIK58644.1 - 0.22 11.9 1.8 1.1e+02 3.3 0.1 3.5 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Pirin PF02678.16 KIK58645.1 - 5.6e-27 93.9 0.2 8.6e-27 93.2 0.2 1.2 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KIK58645.1 - 1.7e-09 37.2 0.6 3.2e-07 29.9 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 KIK58645.1 - 0.00015 21.9 0.0 0.0042 17.2 0.0 2.8 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain DUF2263 PF10021.9 KIK58646.1 - 1.6e-21 77.2 0.1 3e-13 50.4 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KIK58646.1 - 0.0032 17.5 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain ABC2_membrane PF01061.24 KIK58647.1 - 1.3e-32 113.0 22.7 2.5e-32 112.0 22.7 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KIK58647.1 - 9e-28 97.5 0.0 1.7e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK58647.1 - 3.2e-06 27.2 0.0 0.058 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 KIK58647.1 - 2.2e-05 24.7 9.2 2.2e-05 24.7 9.2 4.4 4 0 0 4 4 4 2 EGF-like domain AAA_29 PF13555.6 KIK58647.1 - 0.00051 19.7 0.2 0.0013 18.4 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK58647.1 - 0.0023 17.9 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KIK58647.1 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIK58647.1 - 0.0092 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KIK58647.1 - 0.043 14.1 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK58647.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK58647.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK58647.1 - 0.082 13.2 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIK58647.1 - 0.11 11.9 0.0 2.3 7.6 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KIK58647.1 - 0.16 11.1 26.6 0.061 12.4 23.8 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein TniB PF05621.11 KIK58647.1 - 0.22 10.9 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein MARVEL PF01284.23 KIK58648.1 - 1.3 9.1 6.8 1.9 8.5 0.8 2.4 2 1 0 2 2 2 0 Membrane-associating domain Ferric_reduct PF01794.19 KIK58648.1 - 5.8 7.1 12.5 2 8.5 9.2 2.0 1 1 1 2 2 2 0 Ferric reductase like transmembrane component p450 PF00067.22 KIK58649.1 - 4.8e-13 48.7 0.0 5e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bromodomain PF00439.25 KIK58649.1 - 0.024 14.7 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain DOT1 PF08123.13 KIK58651.1 - 4.4e-23 81.9 0.0 5.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KIK58651.1 - 0.013 16.2 0.1 0.027 15.2 0.1 1.5 1 1 1 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 KIK58651.1 - 0.039 13.0 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.22 KIK58654.1 - 1.8e-72 244.6 0.0 2.7e-71 240.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Anoctamin PF04547.12 KIK58655.1 - 1.4e-104 350.5 0.1 1.6e-104 350.2 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel OPT PF03169.15 KIK58656.1 - 2.5e-129 432.7 56.0 2.8e-129 432.5 56.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Arginase PF00491.21 KIK58657.1 - 2.5e-87 292.9 0.2 3.2e-87 292.6 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIK58657.1 - 0.0024 18.1 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain RPE65 PF03055.15 KIK58658.1 - 1.2e-109 367.6 0.0 1.4e-109 367.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein p450 PF00067.22 KIK58662.1 - 5.6e-05 22.1 0.1 0.0086 14.9 0.0 2.8 3 0 0 3 3 3 2 Cytochrome P450 p450 PF00067.22 KIK58663.1 - 1.9e-51 175.2 0.0 1.6e-50 172.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK58665.1 - 2.6e-44 151.7 0.0 3.8e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Yippee-Mis18 PF03226.14 KIK58666.1 - 0.12 12.6 1.5 1.1 9.5 0.5 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Isochorismatase PF00857.20 KIK58667.1 - 6.6e-18 65.5 0.1 9.3e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family 2-Hacid_dh_C PF02826.19 KIK58668.1 - 2e-49 167.3 0.0 3.1e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK58668.1 - 9.4e-20 70.6 0.0 1.2e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK58668.1 - 5.2e-06 26.7 0.0 1.7e-05 25.0 0.0 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3884 PF13024.6 KIK58668.1 - 0.0013 18.2 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3884) Shikimate_DH PF01488.20 KIK58668.1 - 0.005 16.9 0.0 0.071 13.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK58668.1 - 0.036 14.5 0.1 1.4 9.4 0.0 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding FSH1 PF03959.13 KIK58669.1 - 5.5e-48 163.4 0.0 6.4e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KIK58669.1 - 4.4e-05 23.4 0.1 2.1 8.1 0.1 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIK58669.1 - 0.00063 20.4 0.0 0.032 14.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK58669.1 - 0.0012 18.6 0.0 0.083 12.5 0.0 2.9 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIK58669.1 - 0.15 11.9 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KIK58671.1 - 1.2e-19 70.4 46.7 7e-19 68.0 44.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Retrotrans_gag PF03732.17 KIK58676.1 - 9.6e-07 29.0 0.0 3.2e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK58676.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) RuvA_C PF07499.13 KIK58676.1 - 0.76 10.3 2.5 41 4.7 0.0 3.2 3 0 0 3 3 3 0 RuvA, C-terminal domain PH_9 PF15410.6 KIK58678.1 - 4.5e-17 62.5 0.0 7.4e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK58678.1 - 0.0053 17.3 0.0 0.0083 16.6 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF2278 PF10042.9 KIK58678.1 - 0.046 13.7 0.0 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) LRRC37 PF15779.5 KIK58679.1 - 0.094 13.1 3.1 0.12 12.8 3.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family AcetylCoA_hydro PF02550.15 KIK58680.1 - 6.2e-33 114.4 0.0 1.1e-32 113.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIK58680.1 - 8e-31 107.1 0.0 2.3e-30 105.6 0.0 1.8 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain WD40 PF00400.32 KIK58681.1 - 1.1e-129 418.5 91.3 2.3e-10 40.9 1.0 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58681.1 - 3.4e-37 126.6 23.2 0.0043 17.3 0.1 13.8 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK58681.1 - 3.7e-18 65.9 19.2 0.0034 16.8 0.1 8.5 3 2 6 9 9 9 7 WD40-like domain Frtz PF11768.8 KIK58681.1 - 1.5e-08 33.4 4.1 2.3 6.4 0.1 8.9 1 1 7 10 10 10 2 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK58681.1 - 4.5e-08 32.0 17.5 0.034 12.7 0.2 5.5 3 2 1 5 5 5 3 Cytochrome D1 heme domain NACHT PF05729.12 KIK58681.1 - 1.4e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF727 PF05303.12 KIK58681.1 - 0.0006 19.8 2.5 26 4.9 0.0 6.7 5 3 3 8 8 8 0 Protein of unknown function (DUF727) PQQ_3 PF13570.6 KIK58681.1 - 0.0013 19.1 19.4 11 6.6 0.0 9.9 12 0 0 12 12 10 1 PQQ-like domain Ge1_WD40 PF16529.5 KIK58681.1 - 0.016 14.2 18.9 0.37 9.7 1.2 8.0 1 1 6 8 8 8 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coat_X PF07552.11 KIK58681.1 - 0.034 14.0 3.6 1.1 9.1 0.1 4.5 4 0 0 4 4 4 0 Spore Coat Protein X and V domain NB-ARC PF00931.22 KIK58681.1 - 0.06 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Kelch_6 PF13964.6 KIK58681.1 - 0.062 13.6 15.1 4.4 7.8 0.2 6.8 7 0 0 7 7 6 0 Kelch motif AAA PF00004.29 KIK58681.1 - 0.16 12.4 0.0 0.59 10.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KIK58681.1 - 9 6.4 18.3 97 3.1 0.0 9.3 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Cep57_CLD_2 PF14197.6 KIK58682.1 - 0.021 14.9 1.3 0.038 14.1 1.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 MRFAP1 PF15155.6 KIK58683.1 - 0.012 16.1 0.6 0.018 15.6 0.6 1.2 1 0 0 1 1 1 0 MORF4 family-associated protein1 Transgly_assoc PF04226.13 KIK58683.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein WD40 PF00400.32 KIK58685.1 - 3e-07 31.0 0.5 0.0083 17.0 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58685.1 - 0.0013 19.0 0.0 0.057 13.7 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CUE PF02845.16 KIK58686.1 - 0.044 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 CUE domain SlyX PF04102.12 KIK58687.1 - 0.0088 16.6 0.3 0.037 14.7 0.3 2.1 1 0 0 1 1 1 1 SlyX GCR1_C PF12550.8 KIK58687.1 - 0.054 13.8 0.4 0.14 12.5 0.4 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes PPP4R2 PF09184.11 KIK58687.1 - 1.8 8.1 7.7 3 7.4 7.7 1.2 1 0 0 1 1 1 0 PPP4R2 F-box-like PF12937.7 KIK58688.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like Transposase_21 PF02992.14 KIK58691.1 - 6.3e-09 35.4 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF3302 PF11742.8 KIK58691.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) DUF1770 PF08589.10 KIK58692.1 - 1.8e-06 28.8 1.5 1.8e-06 28.8 1.5 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) NAD_binding_4 PF07993.12 KIK58693.1 - 6.7e-26 91.0 0.0 9.2e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK58693.1 - 4.1e-07 29.7 0.0 1.1e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK58693.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK58693.1 - 0.024 13.7 0.0 0.29 10.1 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIK58693.1 - 0.03 13.5 0.0 0.059 12.5 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PI-PLC-X PF00388.19 KIK58693.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Tri3 PF07428.11 KIK58694.1 - 1.2e-20 73.8 0.0 4.2e-20 72.1 0.0 1.7 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 WES_acyltransf PF03007.16 KIK58694.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Gemini_AC4_5_2 PF08464.10 KIK58696.1 - 0.094 12.7 1.1 3 7.8 0.1 2.8 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region Toxin_6 PF05453.12 KIK58696.1 - 5.1 7.6 7.7 16 6.0 7.7 1.9 1 0 0 1 1 1 0 BmTXKS1/BmP02 toxin family FYDLN_acid PF09538.10 KIK58697.1 - 0.26 12.0 0.0 0.46 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BTB PF00651.31 KIK58700.1 - 0.0002 21.5 0.1 0.0012 19.0 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain Stealth_CR4 PF17103.5 KIK58701.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 PX PF00787.24 KIK58702.1 - 1.6e-13 50.6 0.0 2.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 PX domain Putative_PNPOx PF01243.20 KIK58703.1 - 2.5e-05 24.4 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3144 PF11342.8 KIK58704.1 - 0.07 13.4 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) RVT_2 PF07727.14 KIK58705.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cupredoxin_1 PF13473.6 KIK58705.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain HET-S PF17108.5 KIK58706.1 - 1.7 8.5 5.5 26 4.7 0.0 3.6 4 0 0 4 4 4 0 N-terminal small S protein of HET, non-prionic TBCC_N PF16752.5 KIK58711.1 - 0.016 15.6 0.4 0.023 15.1 0.1 1.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF2408 PF10303.9 KIK58711.1 - 0.041 14.5 0.4 0.16 12.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Allexi_40kDa PF05549.11 KIK58711.1 - 0.052 13.1 0.5 0.057 12.9 0.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF5344 PF17279.2 KIK58711.1 - 0.089 13.4 1.5 0.13 12.9 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Ntox28 PF15605.6 KIK58712.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 28 MEDS PF14417.6 KIK58712.1 - 0.061 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF5455 PF17537.2 KIK58712.1 - 0.19 12.1 0.1 0.19 12.1 0.1 4.3 5 1 0 5 5 5 0 Family of unknown function (DUF5455) Arm PF00514.23 KIK58713.1 - 2.4e-31 106.8 4.8 1.9e-11 43.6 0.2 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KIK58713.1 - 1.2e-17 63.2 0.2 2.1e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KIK58713.1 - 0.00014 22.3 0.1 0.25 11.9 0.0 2.8 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KIK58713.1 - 0.00023 21.5 0.0 0.48 10.8 0.0 2.5 1 1 0 2 2 2 2 HEAT repeats V-ATPase_H_C PF11698.8 KIK58713.1 - 0.0019 18.3 0.1 0.16 12.1 0.0 2.7 2 1 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.22 KIK58713.1 - 0.0021 18.2 0.1 0.84 10.1 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.20 KIK58713.1 - 0.013 14.1 0.1 0.25 9.9 0.0 2.4 1 1 0 2 2 2 0 Adaptin N terminal region Arm_2 PF04826.13 KIK58713.1 - 0.023 14.2 0.3 0.91 8.9 0.0 2.1 2 0 0 2 2 2 0 Armadillo-like Katanin_con80 PF13925.6 KIK58713.1 - 0.048 13.7 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Mo25 PF08569.11 KIK58713.1 - 0.052 12.9 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Mo25-like DMP12 PF16779.5 KIK58713.1 - 0.077 13.0 0.0 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 DNA-mimic protein DUF2868 PF11067.8 KIK58715.1 - 0.028 14.0 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) NmrA PF05368.13 KIK58717.1 - 4.3e-25 88.6 0.0 5.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK58717.1 - 1.3e-07 31.7 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding p450 PF00067.22 KIK58719.1 - 9e-30 103.8 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cytokin_check_N PF10407.9 KIK58719.1 - 0.13 12.2 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus OST-HTH PF12872.7 KIK58720.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 OST-HTH/LOTUS domain UPF0182 PF03699.13 KIK58720.1 - 0.37 8.9 2.1 0.54 8.3 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF3413 PF11893.8 KIK58720.1 - 3 7.0 9.1 6.6 5.8 8.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) DUF3290 PF11694.8 KIK58721.1 - 0.0011 18.9 3.4 0.0012 18.9 1.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3290) DUF2678 PF10856.8 KIK58721.1 - 0.0044 16.9 2.0 0.0044 16.9 2.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2678) DUF4131 PF13567.6 KIK58721.1 - 0.18 11.5 5.1 0.54 9.9 2.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Spem1 PF15670.5 KIK58721.1 - 0.3 10.6 0.1 0.51 9.9 0.1 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 LapA_dom PF06305.11 KIK58721.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2721 PF11026.8 KIK58721.1 - 3.3 7.6 8.5 0.81 9.6 4.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) IBV_3C PF03620.13 KIK58722.1 - 0.23 11.9 2.4 0.21 12.1 0.3 2.2 2 0 0 2 2 2 0 IBV 3C protein DUF1180 PF06679.12 KIK58724.1 - 0.0018 18.7 1.5 0.0018 18.7 1.5 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1180) TRAP_alpha PF03896.16 KIK58724.1 - 0.26 10.5 0.0 0.38 9.9 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3283 PF11686.8 KIK58730.1 - 0.072 13.0 0.7 2.1 8.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3283) Amidase_3 PF01520.18 KIK58731.1 - 0.0011 19.1 0.1 0.0031 17.6 0.1 2.1 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase zf-CCHC PF00098.23 KIK58732.1 - 5.4e-06 26.3 1.4 1.1e-05 25.2 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIK58732.1 - 0.012 15.3 1.4 0.019 14.7 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 KIK58733.1 - 8.1e-05 22.4 0.0 0.01 15.6 0.0 2.3 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIK58733.1 - 0.0093 16.5 0.0 0.026 15.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK58733.1 - 0.018 15.7 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 KIK58733.1 - 0.11 12.2 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease p450 PF00067.22 KIK58736.1 - 6.7e-40 137.2 0.0 9.6e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KIK58738.1 - 1.2e-25 90.5 0.0 1.5e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK58738.1 - 3.4e-08 33.6 0.0 4.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Putative_PNPOx PF01243.20 KIK58743.1 - 0.015 15.5 0.0 0.083 13.1 0.0 2.0 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.7 KIK58745.1 - 0.0008 19.3 1.4 0.0022 17.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK58745.1 - 0.0012 18.7 1.0 0.0038 17.1 1.0 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK58745.1 - 0.0078 16.1 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 F-box CcmD PF04995.14 KIK58748.1 - 0.017 15.2 0.2 0.031 14.4 0.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) LPG_synthase_TM PF03706.13 KIK58748.1 - 0.042 13.4 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region zf-C2H2_6 PF13912.6 KIK58748.1 - 0.1 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger VSP PF03302.13 KIK58748.1 - 0.16 10.8 0.2 0.2 10.5 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein LapA_dom PF06305.11 KIK58748.1 - 0.26 11.1 0.3 0.43 10.4 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pheromone PF08015.11 KIK58750.1 - 4.8e-05 24.3 4.7 0.00016 22.6 4.7 1.8 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 KIK58751.1 - 0.0012 19.8 3.2 0.0024 18.9 3.2 1.5 1 1 0 1 1 1 1 Fungal mating-type pheromone F-box-like PF12937.7 KIK58753.1 - 1.8e-05 24.5 0.2 5e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK58753.1 - 0.00048 19.9 0.5 0.0013 18.5 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK58753.1 - 0.018 14.9 0.6 0.039 13.8 0.1 1.9 2 0 0 2 2 2 0 F-box PRANC PF09372.10 KIK58753.1 - 0.044 14.1 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 PRANC domain STE3 PF02076.15 KIK58755.1 - 6.8e-112 373.4 18.9 8.4e-112 373.1 18.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor TNV_CP PF03898.13 KIK58755.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein Pheromone PF08015.11 KIK58756.1 - 0.00059 20.8 1.8 0.00079 20.4 1.8 1.2 1 0 0 1 1 1 1 Fungal mating-type pheromone Con-6 PF10346.9 KIK58757.1 - 1.9e-13 50.2 0.2 2.5e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 Conidiation protein 6 Pheromone PF08015.11 KIK58758.1 - 0.0022 19.0 1.1 0.01 16.9 1.1 2.1 1 1 0 1 1 1 1 Fungal mating-type pheromone Peptidase_M56 PF05569.11 KIK58759.1 - 0.14 11.3 4.0 1.9 7.6 0.2 2.5 2 1 0 2 2 2 0 BlaR1 peptidase M56 DUF3290 PF11694.8 KIK58760.1 - 1.4 8.9 4.8 1.8 8.5 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4131 PF13567.6 KIK58760.1 - 4.3 7.0 8.9 0.092 12.4 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Pheromone PF08015.11 KIK58761.1 - 0.0043 18.1 0.1 0.0059 17.6 0.1 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone DUF1129 PF06570.11 KIK58762.1 - 0.065 12.7 2.3 0.19 11.2 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4079 PF13301.6 KIK58762.1 - 0.32 11.1 5.3 0.57 10.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3290 PF11694.8 KIK58762.1 - 1.3 8.9 3.6 0.83 9.6 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) F-box-like PF12937.7 KIK58764.1 - 0.00077 19.3 0.1 0.0033 17.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK58764.1 - 0.0019 18.0 1.3 0.0046 16.8 0.2 2.3 2 0 0 2 2 2 1 F-box domain Sld5 PF05916.11 KIK58764.1 - 0.028 14.9 0.0 0.053 14.0 0.0 1.7 1 1 0 1 1 1 0 GINS complex protein Pheromone PF08015.11 KIK58766.1 - 5.9e-07 30.4 0.4 8.4e-07 29.9 0.4 1.3 1 0 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 KIK58767.1 - 8.6e-102 340.2 22.8 1e-101 340.0 22.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.11 KIK58768.1 - 3e-12 47.4 1.1 3.6e-12 47.1 1.1 1.1 1 0 0 1 1 1 1 Fungal mating-type pheromone HMW1C_N PF18071.1 KIK58770.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 HMW1C N-terminal PAS PF00989.25 KIK58773.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold Glyco_hydro_16 PF00722.21 KIK58774.1 - 7e-06 25.6 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 F-box-like PF12937.7 KIK58776.1 - 0.0002 21.2 0.0 0.00058 19.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK58776.1 - 0.0006 19.6 0.1 0.0006 19.6 0.1 2.4 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 KIK58776.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KIK58777.1 - 8.1e-06 25.6 0.5 2.4e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK58777.1 - 0.00023 20.9 0.1 0.00053 19.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 KIK58777.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 PRANC domain DUF4638 PF15472.6 KIK58777.1 - 0.025 14.3 0.1 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4638) SNF2_N PF00176.23 KIK58778.1 - 6.9e-46 156.6 0.0 1.9e-45 155.1 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KIK58778.1 - 5e-06 26.3 12.0 8.8e-06 25.5 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK58778.1 - 7e-06 25.8 9.3 1.2e-05 25.0 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK58778.1 - 7.7e-06 25.7 9.2 1.5e-05 24.8 9.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK58778.1 - 0.00022 21.5 15.3 0.00041 20.6 15.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK58778.1 - 0.00024 21.0 13.9 0.00044 20.2 13.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK58778.1 - 0.0035 17.1 12.8 0.0065 16.3 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KIK58778.1 - 0.019 15.3 0.2 0.056 13.8 0.0 1.9 2 0 0 2 2 1 0 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KIK58778.1 - 0.061 13.6 8.5 0.14 12.5 8.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain TFIIA PF03153.13 KIK58778.1 - 0.25 11.3 9.8 0.63 10.0 5.1 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit zf-RING_6 PF14835.6 KIK58778.1 - 0.31 11.0 4.4 0.72 9.8 4.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KIK58778.1 - 0.5 10.0 9.4 0.95 9.1 9.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KIK58778.1 - 0.6 10.2 10.1 1.5 8.9 10.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PilO PF04350.13 KIK58778.1 - 0.63 10.2 3.9 2.3 8.4 3.9 1.9 1 0 0 1 1 1 0 Pilus assembly protein, PilO zf-C3HC4_4 PF15227.6 KIK58778.1 - 2.8 8.2 10.0 5.7 7.2 10.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KIK58778.1 - 3.4 7.8 6.2 11 6.2 6.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF485 PF04341.12 KIK58779.1 - 8.9 6.4 11.6 9.5 6.2 3.9 3.2 2 1 1 3 3 3 0 Protein of unknown function, DUF485 DUF1652 PF07865.11 KIK58780.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF805 PF05656.14 KIK58780.1 - 0.25 11.8 3.6 1.5 9.3 2.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4381 PF14316.6 KIK58780.1 - 0.49 10.6 3.7 0.45 10.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ETX_MTX2 PF03318.13 KIK58781.1 - 1.5e-09 38.0 8.7 2.2e-09 37.4 8.7 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 KIK58781.1 - 8.7e-09 35.1 1.7 1.3e-08 34.5 1.7 1.2 1 0 0 1 1 1 1 Aerolysin toxin CBM65_1 PF18259.1 KIK58781.1 - 0.071 13.3 1.5 1.4 9.1 0.1 2.8 2 1 0 3 3 3 0 Carbohydrate binding module 65 domain 1 DUF5329 PF17263.2 KIK58783.1 - 0.014 15.6 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5329) PilO PF04350.13 KIK58783.1 - 0.11 12.6 3.2 0.2 11.8 3.2 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF1754 PF08555.10 KIK58783.1 - 0.11 13.3 4.8 0.22 12.3 4.8 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF1722 PF08349.11 KIK58783.1 - 0.14 12.4 0.5 0.34 11.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Herpes_IE68 PF02479.16 KIK58783.1 - 0.14 11.7 0.4 0.26 10.9 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus immediate early protein Use1 PF09753.9 KIK58783.1 - 0.62 9.7 8.7 1.1 8.9 8.7 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Vfa1 PF08432.10 KIK58783.1 - 3.9 7.8 5.6 5.7 7.2 5.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Prefoldin PF02996.17 KIK58785.1 - 1.3e-27 96.0 0.5 2.1e-25 89.0 0.3 2.4 1 1 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 KIK58785.1 - 0.21 12.0 3.9 0.6 10.5 0.1 3.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PS_Dcarbxylase PF02666.15 KIK58786.1 - 1.1e-38 132.9 0.0 1.5e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KIK58786.1 - 8.7e-32 110.0 0.0 1.4e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Viral_helicase1 PF01443.18 KIK58790.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RRM_1 PF00076.22 KIK58791.1 - 1.4e-70 233.0 0.1 1.6e-14 53.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK58791.1 - 1.5e-05 24.7 0.0 0.02 14.8 0.0 4.3 5 0 0 5 5 5 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIK58791.1 - 0.0042 17.1 0.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KIK58791.1 - 0.012 15.7 0.0 3.3 7.9 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 RRM_Rrp7 PF17799.1 KIK58791.1 - 0.038 13.8 1.4 6.3 6.6 0.1 4.1 5 1 0 5 5 5 0 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KIK58792.1 - 1.2e-16 60.2 0.1 5.3e-08 32.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PS_Dcarbxylase PF02666.15 KIK58793.1 - 7.4e-40 136.6 0.0 1.1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KIK58793.1 - 9.6e-36 122.8 0.0 1.4e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RRM_1 PF00076.22 KIK58794.1 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF565 PF04483.12 KIK58796.1 - 0.12 12.9 0.6 0.12 12.9 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF565) MerE PF05052.12 KIK58796.1 - 0.2 11.6 4.1 0.067 13.1 1.1 1.8 2 0 0 2 2 2 0 MerE protein Syndecan PF01034.20 KIK58796.1 - 1.1 9.2 2.7 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Syndecan domain YlaH PF14036.6 KIK58800.1 - 0.0051 17.1 0.9 0.011 16.1 0.9 1.5 1 0 0 1 1 1 1 YlaH-like protein STE3 PF02076.15 KIK58801.1 - 6.4e-115 383.3 20.2 7.7e-115 383.1 20.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KIK58802.1 - 4.8e-48 163.8 12.3 6.3e-48 163.4 12.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Colicin_V PF02674.16 KIK58802.1 - 9.2 6.2 8.9 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 Colicin V production protein GREB1 PF15782.5 KIK58808.1 - 6.9 3.6 18.8 8.2 3.4 18.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Retrotran_gag_2 PF14223.6 KIK58812.1 - 0.00069 19.3 0.5 0.00088 19.0 0.5 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Minor_capsid_3 PF12691.7 KIK58813.1 - 0.18 12.1 2.0 9.9 6.6 0.7 3.0 1 1 1 2 2 2 0 Minor capsid protein from bacteriophage Glyco_hydro_7 PF00840.20 KIK58814.1 - 8.1e-199 660.8 13.7 9.2e-199 660.6 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Trefoil PF00088.18 KIK58814.1 - 0.38 10.7 8.4 4.6 7.2 1.1 3.1 3 0 0 3 3 3 0 Trefoil (P-type) domain TFIIE_alpha PF02002.17 KIK58815.1 - 3.3e-06 26.9 1.0 4.9e-06 26.4 1.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit CsiV PF10972.8 KIK58815.1 - 0.069 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV TF_Zn_Ribbon PF08271.12 KIK58815.1 - 0.089 12.3 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 KIK58815.1 - 0.095 12.6 0.6 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 KIK58816.1 - 1.8e-110 357.7 31.9 4.7e-10 39.9 0.0 11.4 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58816.1 - 3.8e-52 174.6 14.0 0.00011 22.4 0.0 11.1 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK58816.1 - 1.8e-21 75.5 3.2 0.26 11.3 0.1 11.3 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK58816.1 - 3.1e-11 42.3 0.0 2.2 6.5 0.0 8.8 6 3 0 8 8 8 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK58816.1 - 9.9e-10 37.9 12.2 6 5.7 0.0 10.0 2 2 9 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK58816.1 - 4.7e-08 33.3 0.5 3.3 8.3 0.0 7.6 6 2 3 9 9 9 1 PQQ-like domain Me-amine-dh_H PF06433.11 KIK58816.1 - 6.8e-07 28.5 0.0 4.1 6.2 0.0 5.6 2 1 4 7 7 7 2 Methylamine dehydrogenase heavy chain (MADH) WD40_like PF17005.5 KIK58816.1 - 1.6e-06 27.7 0.1 25 4.1 0.0 7.7 6 4 2 10 10 10 0 WD40-like domain Nup160 PF11715.8 KIK58816.1 - 3.2e-06 26.1 0.1 2.5 6.7 0.0 6.7 4 3 5 9 9 9 1 Nucleoporin Nup120/160 PQQ PF01011.21 KIK58816.1 - 3.8e-06 26.6 0.0 1e+02 3.1 0.0 7.7 9 0 0 9 9 8 0 PQQ enzyme repeat FeThRed_A PF02941.15 KIK58816.1 - 9.8e-06 25.6 3.9 14 5.9 0.0 7.0 3 2 5 8 8 8 0 Ferredoxin thioredoxin reductase variable alpha chain DUF3553 PF12073.8 KIK58816.1 - 1.3e-05 24.8 4.9 24 4.8 0.0 7.9 9 0 0 9 9 8 0 Protein of unknown function (DUF3553) DUF4221 PF13970.6 KIK58816.1 - 0.00057 19.5 0.0 1.7 8.2 0.0 4.2 2 1 4 6 6 6 1 Domain of unknown function (DUF4221) Peptidase_S9_N PF02897.15 KIK58816.1 - 0.00065 18.6 0.5 2.2 7.0 0.0 4.8 2 2 0 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 KIK58816.1 - 0.0069 16.0 6.6 77 3.1 0.0 8.0 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature 5-FTHF_cyc-lig PF01812.20 KIK58816.1 - 0.16 11.8 0.0 1.6e+02 2.0 0.0 4.9 6 1 1 7 7 7 0 5-formyltetrahydrofolate cyclo-ligase family DUF4279 PF14106.6 KIK58816.1 - 0.17 12.1 2.0 34 4.7 0.0 4.1 3 2 3 6 6 5 0 Domain of unknown function (DUF4279) DUF1797 PF08796.10 KIK58816.1 - 0.2 11.7 0.0 4.7 7.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Nucleoporin_N PF08801.11 KIK58816.1 - 0.36 9.5 4.7 1.8 7.2 0.2 3.7 2 1 0 4 4 4 0 Nup133 N terminal like Cuticle_4 PF15955.5 KIK58816.1 - 7.7 7.3 17.3 61 4.4 0.1 8.0 10 1 0 11 11 10 0 Cuticle protein F-box-like PF12937.7 KIK58817.1 - 0.04 13.8 0.1 0.14 12.1 0.1 2.0 1 1 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIK58819.1 - 0.0029 17.5 2.8 0.0029 17.5 2.8 2.3 2 1 0 2 2 2 1 F-box-like Pkinase PF00069.25 KIK58820.1 - 0.0069 15.8 0.0 0.0098 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Cellulase PF00150.18 KIK58821.1 - 1.4e-31 110.0 0.0 2.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Myb_DNA-binding PF00249.31 KIK58822.1 - 9.5e-08 32.1 0.0 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK58822.1 - 1.5e-07 31.5 0.0 2e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KIK58822.1 - 0.25 11.4 0.1 0.48 10.5 0.1 1.4 1 0 0 1 1 1 0 SLIDE Pyr_redox_2 PF07992.14 KIK58823.1 - 3.2e-34 118.5 0.0 4e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK58823.1 - 1e-14 54.8 0.0 3e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK58823.1 - 1.9e-06 28.0 0.6 0.03 14.3 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIK58823.1 - 0.00018 20.8 0.0 0.25 10.4 0.0 3.1 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIK58823.1 - 0.00096 18.8 7.0 1.2 8.6 0.2 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK58823.1 - 0.0029 16.9 0.0 0.0064 15.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK58823.1 - 0.004 17.3 0.4 0.056 13.7 0.0 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK58823.1 - 0.0062 15.6 0.2 7.8 5.4 0.0 3.5 3 1 1 4 4 4 1 Lycopene cyclase protein DUF498 PF04430.14 KIK58823.1 - 0.031 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) CBP_BcsQ PF06564.12 KIK58823.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ FAD_binding_3 PF01494.19 KIK58823.1 - 0.12 11.6 0.5 1.6 7.9 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KIK58823.1 - 0.2 10.5 1.1 21 3.8 0.0 3.2 3 1 0 4 4 4 0 Tryptophan halogenase GIDA PF01134.22 KIK58823.1 - 0.54 9.3 2.9 2.2 7.3 0.0 2.8 3 1 0 3 3 3 0 Glucose inhibited division protein A MMR_HSR1 PF01926.23 KIK58824.1 - 7.9e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK58824.1 - 5.3e-06 26.4 0.5 0.001 19.0 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KIK58824.1 - 3.3e-05 23.2 0.9 0.028 13.6 0.1 2.4 2 0 0 2 2 2 2 G-protein alpha subunit Septin PF00735.18 KIK58824.1 - 8e-05 22.1 0.9 0.00066 19.0 0.8 2.2 1 1 0 1 1 1 1 Septin DUF815 PF05673.13 KIK58824.1 - 0.00022 20.5 0.1 0.00042 19.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Roc PF08477.13 KIK58824.1 - 0.0033 17.6 0.1 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIK58824.1 - 0.0043 16.9 1.3 0.091 12.5 0.5 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KIK58824.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.16 KIK58824.1 - 0.0068 15.8 0.2 0.089 12.1 0.0 2.5 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 KIK58824.1 - 0.014 14.9 0.3 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIK58824.1 - 0.015 15.6 0.1 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KIK58824.1 - 0.016 15.8 0.7 0.035 14.6 0.7 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KIK58824.1 - 0.016 15.6 0.3 0.062 13.7 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 KIK58824.1 - 0.017 14.2 0.1 0.047 12.8 0.1 1.7 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 KIK58824.1 - 0.033 13.8 1.0 1 9.0 0.0 2.6 2 1 0 2 2 2 0 Ras family Dynamin_N PF00350.23 KIK58824.1 - 0.058 13.4 0.7 0.22 11.6 0.7 2.0 1 1 0 1 1 1 0 Dynamin family AAA_24 PF13479.6 KIK58824.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK58824.1 - 0.097 12.6 1.3 0.4 10.5 1.3 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Gtr1_RagA PF04670.12 KIK58824.1 - 0.13 11.5 1.6 0.29 10.5 1.6 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 KIK58824.1 - 0.14 11.2 0.4 0.31 10.0 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein F-box-like PF12937.7 KIK58825.1 - 0.00039 20.2 2.3 0.0026 17.6 2.3 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK58825.1 - 0.12 12.9 7.2 13 6.4 0.4 4.5 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK58825.1 - 2.6 8.0 10.1 1.2 9.1 1.5 3.6 3 1 0 3 3 3 0 F-box domain TPR_12 PF13424.6 KIK58826.1 - 3.6e-48 161.7 33.1 5.7e-13 49.0 0.6 4.9 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK58826.1 - 4.9e-33 110.6 25.8 0.00045 20.1 0.0 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.28 KIK58826.1 - 3.1e-31 105.9 30.7 0.00031 20.4 0.3 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIK58826.1 - 2.5e-24 83.4 34.3 0.0012 18.8 0.5 8.4 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK58826.1 - 1.3e-17 64.2 10.6 2.8e-08 33.5 0.9 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 KIK58826.1 - 9.6e-15 54.0 10.6 0.3 12.0 0.0 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK58826.1 - 8.4e-14 50.7 21.4 0.021 14.2 0.0 7.3 7 0 0 7 7 7 4 SHNi-TPR TPR_7 PF13176.6 KIK58826.1 - 9.1e-14 50.4 18.2 0.09 12.9 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat SNAP PF14938.6 KIK58826.1 - 9.6e-14 51.5 10.9 8.3e-07 28.7 1.0 3.1 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 KIK58826.1 - 9.2e-13 48.5 31.6 0.075 13.5 0.2 6.2 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KIK58826.1 - 2.2e-11 43.2 21.2 0.048 13.6 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK58826.1 - 9.8e-11 42.1 15.0 0.094 13.4 0.3 7.3 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK58826.1 - 3.3e-10 39.5 23.1 1.2 8.9 0.2 8.6 8 0 0 8 8 8 3 TPR repeat TPR_21 PF09976.9 KIK58826.1 - 9.5e-10 38.5 19.4 0.0042 16.8 0.4 4.5 2 2 2 4 4 4 4 Tetratricopeptide repeat-like domain RPN7 PF10602.9 KIK58826.1 - 2.8e-09 36.9 15.6 0.18 11.5 0.4 5.8 1 1 6 7 7 7 5 26S proteasome subunit RPN7 FlaC_arch PF05377.11 KIK58826.1 - 7.1e-09 35.9 6.2 17 5.9 0.0 7.7 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) TPR_6 PF13174.6 KIK58826.1 - 3.9e-08 33.4 20.2 2.7 8.8 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat UPF0054 PF02130.17 KIK58826.1 - 1.6e-06 27.9 1.4 14 5.5 0.0 5.9 1 1 4 5 5 5 0 Uncharacterized protein family UPF0054 FRB_dom PF08771.11 KIK58826.1 - 6.6e-06 26.5 6.7 0.011 16.1 0.2 4.3 2 2 3 5 5 5 1 FKBP12-rapamycin binding domain TRPM_tetra PF16519.5 KIK58826.1 - 7.7e-06 25.9 14.0 8 6.7 0.1 7.5 7 0 0 7 7 7 0 Tetramerisation domain of TRPM ANAPC3 PF12895.7 KIK58826.1 - 4.2e-05 23.7 15.6 0.64 10.3 0.5 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 HetR_C PF18460.1 KIK58826.1 - 0.00016 21.5 8.6 6.9 6.7 0.0 6.4 2 1 6 8 8 8 0 Heterocyst differentiation regulator C-terminal Hood domain DUF695 PF05117.12 KIK58826.1 - 0.00018 21.7 5.1 22 5.2 0.0 5.8 4 2 2 6 6 6 0 Family of unknown function (DUF695) Ribosomal_L16 PF00252.18 KIK58826.1 - 0.00026 21.0 4.3 5.5 7.0 0.0 5.5 1 1 5 6 6 6 0 Ribosomal protein L16p/L10e T4SS PF07996.11 KIK58826.1 - 0.00046 20.6 16.4 0.6 10.5 1.0 4.4 1 1 2 4 4 4 2 Type IV secretion system proteins Syntaxin-6_N PF09177.11 KIK58826.1 - 0.00052 20.5 8.8 2.7 8.6 0.2 4.6 1 1 4 6 6 6 1 Syntaxin 6, N-terminal Cystatin PF00031.21 KIK58826.1 - 0.00053 20.2 7.5 34 4.8 0.0 6.4 7 0 0 7 7 7 0 Cystatin domain TPR_9 PF13371.6 KIK58826.1 - 0.0029 17.7 7.4 18 5.5 0.3 6.3 2 2 4 6 6 6 0 Tetratricopeptide repeat DUF1529 PF07485.11 KIK58826.1 - 0.0038 17.1 0.1 19 5.2 0.0 3.6 3 1 2 5 5 5 0 Domain of Unknown Function (DUF1259) Wzy_C_2 PF11846.8 KIK58826.1 - 0.0061 16.5 3.9 2.1 8.2 0.1 3.2 1 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal ABC_tran_CTD PF16326.5 KIK58826.1 - 0.016 15.4 31.6 6.3 7.1 2.8 7.2 3 2 2 6 6 6 0 ABC transporter C-terminal domain FliD_N PF02465.18 KIK58826.1 - 0.022 15.4 24.6 5 7.9 1.0 6.8 1 1 5 6 6 6 0 Flagellar hook-associated protein 2 N-terminus HOCHOB PF17943.1 KIK58826.1 - 0.023 15.4 0.2 5 7.9 0.0 3.7 1 1 3 5 5 5 0 Homeobox-cysteine loop-homeobox DUF4122 PF13498.6 KIK58826.1 - 0.047 13.4 10.5 0.66 9.6 0.4 3.5 2 2 1 4 4 4 0 Domain of unknown function (DUF4122) DUF4810 PF16068.5 KIK58826.1 - 0.079 13.5 8.1 1.1e+02 3.4 0.0 6.0 7 0 0 7 7 7 0 Domain of unknown function (DUF4810) DUF2304 PF10066.9 KIK58826.1 - 0.094 12.9 10.1 2.6 8.3 0.1 5.6 6 1 1 7 7 5 0 Uncharacterized conserved protein (DUF2304) IL22 PF14565.6 KIK58826.1 - 0.15 12.3 7.8 13 6.0 0.1 4.2 2 2 2 4 4 4 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor TPR_17 PF13431.6 KIK58826.1 - 0.16 12.4 12.1 38 5.0 0.1 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat CorA PF01544.18 KIK58826.1 - 0.17 11.1 15.8 0.64 9.3 2.5 2.6 1 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF4606 PF15379.6 KIK58826.1 - 0.18 12.0 0.5 13 6.1 0.0 3.5 2 2 4 6 6 6 0 Domain of unknown function (DUF4606) MCC-bdg_PDZ PF10506.9 KIK58826.1 - 0.27 11.3 17.3 5.5 7.1 0.8 6.5 4 3 3 7 7 7 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AhpC-TSA_2 PF13911.6 KIK58826.1 - 0.5 10.5 5.3 5.4e+02 0.7 5.3 4.3 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1110 PF06533.12 KIK58826.1 - 0.77 9.7 7.1 1.9 8.4 0.7 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1110) XisI PF08869.11 KIK58826.1 - 2.6 8.4 5.3 2.1e+02 2.3 0.1 5.1 6 1 1 7 7 7 0 XisI protein Exonuc_VII_S PF02609.16 KIK58826.1 - 7.2 6.8 31.3 4 7.6 0.2 7.2 8 0 0 8 8 8 0 Exonuclease VII small subunit DUF2225 PF09986.9 KIK58826.1 - 9 5.9 11.4 19 4.9 1.6 3.7 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) IBR PF01485.21 KIK58827.1 - 7.4e-07 29.3 6.4 7.4e-07 29.3 6.4 4.1 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIK58827.1 - 1.5e-05 25.3 4.4 1.5e-05 25.3 4.4 4.3 3 2 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK58827.1 - 0.0002 21.3 0.2 0.0002 21.3 0.2 5.0 3 3 1 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK58827.1 - 0.00035 20.4 3.9 0.00035 20.4 3.9 4.2 3 2 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK58827.1 - 0.0014 18.4 3.7 0.0014 18.4 3.7 5.5 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK58827.1 - 0.052 13.3 0.9 0.052 13.3 0.9 3.3 3 0 0 3 3 3 0 RING-like zinc finger Cys_rich_KTR PF14205.6 KIK58827.1 - 0.2 11.5 0.1 0.2 11.5 0.1 3.9 4 1 0 4 4 4 0 Cysteine-rich KTR zf_UBZ PF18439.1 KIK58827.1 - 0.22 11.1 16.8 2.4 7.8 0.1 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KIK58827.1 - 0.55 10.2 0.1 0.55 10.2 0.1 5.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type PCI PF01399.27 KIK58828.1 - 1.5e-10 41.5 0.9 1.4e-08 35.2 0.1 2.3 2 0 0 2 2 2 2 PCI domain Med16 PF11635.8 KIK58828.1 - 0.096 10.6 1.3 0.11 10.4 0.1 1.6 2 0 0 2 2 2 0 Mediator complex subunit 16 Ank_2 PF12796.7 KIK58830.1 - 4e-43 145.9 32.1 1.4e-10 41.6 0.4 6.0 4 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 KIK58830.1 - 3e-36 122.3 28.8 0.0017 18.7 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 KIK58830.1 - 3.9e-34 116.6 9.6 5.7e-05 23.6 0.1 10.4 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK58830.1 - 3.3e-33 109.9 24.4 0.0043 17.4 0.0 13.1 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 KIK58830.1 - 2.4e-20 72.3 12.9 0.0072 16.6 0.0 7.6 6 1 1 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.12 KIK58830.1 - 2.9e-09 37.0 0.0 7.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Acetyltransf_7 PF13508.7 KIK58830.1 - 2.2e-05 24.8 17.9 14 6.2 0.2 9.7 1 1 2 4 4 4 0 Acetyltransferase (GNAT) domain UvrD_C_2 PF13538.6 KIK58830.1 - 0.00037 20.3 0.4 7.5 6.5 0.0 5.2 7 0 0 7 7 6 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KIK58830.1 - 0.00079 19.8 0.0 0.064 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Borealin PF10512.9 KIK58830.1 - 0.007 16.3 0.2 41 4.2 0.0 5.3 6 0 0 6 6 6 0 Cell division cycle-associated protein 8 AAA_14 PF13173.6 KIK58830.1 - 0.0087 16.1 0.0 0.1 12.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KIK58830.1 - 0.019 14.2 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KIK58830.1 - 0.024 15.0 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 KIK58830.1 - 0.044 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 KIK58830.1 - 0.087 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KIK58830.1 - 0.11 12.4 0.3 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Molydop_binding PF01568.21 KIK58830.1 - 0.11 12.5 0.2 18 5.4 0.0 3.9 4 0 0 4 4 4 0 Molydopterin dinucleotide binding domain PCI PF01399.27 KIK58831.1 - 1.3e-05 25.6 0.2 3.5e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 PCI domain TPR_MalT PF17874.1 KIK58831.1 - 0.029 13.8 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 MalT-like TPR region TNFR_16_TM PF18422.1 KIK58832.1 - 3.7 7.6 6.4 0.35 10.9 0.8 2.2 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4618 PF15397.6 KIK58834.1 - 0.13 11.7 2.7 0.18 11.2 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SlyX PF04102.12 KIK58834.1 - 0.18 12.5 0.1 0.18 12.5 0.1 2.4 2 0 0 2 2 2 0 SlyX DUF4763 PF15960.5 KIK58834.1 - 0.37 10.1 2.9 0.6 9.4 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) PKcGMP_CC PF16808.5 KIK58834.1 - 0.87 9.5 3.6 1.7 8.6 3.6 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Glyco_hydro_100 PF12899.7 KIK58835.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Alkaline and neutral invertase MFS_1 PF07690.16 KIK58836.1 - 9.9e-24 83.9 11.5 9.9e-24 83.9 11.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SelK_SelG PF10961.8 KIK58836.1 - 0.14 12.7 0.0 0.44 11.2 0.0 1.8 1 0 0 1 1 1 0 Selenoprotein SelK_SelG SLATT_5 PF18160.1 KIK58838.1 - 0.076 12.3 2.2 0.15 11.4 1.0 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUP PF00674.18 KIK58839.1 - 0.023 14.8 0.6 0.091 12.9 0.6 2.1 1 0 0 1 1 1 0 DUP family AA_permease_2 PF13520.6 KIK58841.1 - 3e-80 270.1 37.8 3.8e-80 269.8 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK58841.1 - 6.8e-13 48.0 28.3 1.3e-12 47.1 28.3 1.5 1 0 0 1 1 1 1 Amino acid permease DUF4208 PF13907.6 KIK58847.1 - 0.087 13.3 0.1 0.3 11.6 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF3740 PF12548.8 KIK58849.1 - 0.024 15.1 1.3 0.069 13.6 1.3 1.8 1 0 0 1 1 1 0 Sulfatase protein DUF693 PF05113.13 KIK58849.1 - 0.039 13.2 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF693) F-box-like PF12937.7 KIK58850.1 - 2.4e-08 33.7 0.6 1e-07 31.7 0.3 2.2 3 0 0 3 3 3 1 F-box-like DUF5536 PF17688.1 KIK58850.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5536) OTT_1508_deam PF14441.6 KIK58852.1 - 6.8e-09 35.6 0.1 1.7e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_S49_N PF08496.10 KIK58855.1 - 0.035 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fez1 PF06818.15 KIK58855.1 - 0.072 13.5 9.5 0.076 13.5 7.6 1.8 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KIK58855.1 - 0.11 11.4 9.7 0.17 10.7 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LRS4 PF10422.9 KIK58855.1 - 0.43 10.1 6.4 0.7 9.4 6.4 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Csm1_N PF18504.1 KIK58855.1 - 0.49 10.8 10.2 0.38 11.1 2.0 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain YscO-like PF16789.5 KIK58855.1 - 0.74 9.8 9.5 1.2 9.2 9.5 1.2 1 0 0 1 1 1 0 YscO-like protein Sec2p PF06428.11 KIK58855.1 - 0.77 9.8 11.6 0.4 10.7 2.0 2.9 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF1635 PF07795.11 KIK58855.1 - 1 9.2 5.1 0.14 12.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Cauli_AT PF03233.13 KIK58855.1 - 1.1 9.2 3.2 2.2 8.2 0.3 2.2 1 1 1 2 2 2 0 Aphid transmission protein DUF641 PF04859.12 KIK58855.1 - 1.3 9.4 7.7 0.77 10.1 3.7 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) KASH_CCD PF14662.6 KIK58855.1 - 1.5 8.6 12.2 3.6 7.4 12.1 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CC2-LZ PF16516.5 KIK58855.1 - 2 8.8 9.2 8.8 6.8 3.7 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PKcGMP_CC PF16808.5 KIK58855.1 - 2.5 8.0 16.9 0.88 9.5 0.3 4.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 KIK58855.1 - 2.6 8.2 16.9 1.2e+02 2.8 16.9 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KIK58855.1 - 3 7.9 13.3 0.49 10.4 5.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 KIK58855.1 - 3.3 7.5 6.9 4.7 7.0 1.1 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spore_III_AB PF09548.10 KIK58855.1 - 3.7 7.6 6.3 9.7 6.3 1.6 2.7 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) ADIP PF11559.8 KIK58855.1 - 9.4 6.3 10.5 28 4.8 9.7 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4633 PF15464.6 KIK58857.1 - 0.067 13.3 1.7 0.098 12.8 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4633) Plavaka PF18759.1 KIK58858.1 - 3.6e-10 39.6 0.0 4.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase BssC_TutF PF08201.11 KIK58860.1 - 0.021 14.9 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 BssC/TutF protein GCM PF03615.15 KIK58866.1 - 0.0033 17.3 0.7 0.0064 16.4 0.7 1.4 1 0 0 1 1 1 1 GCM motif protein p450 PF00067.22 KIK58869.1 - 5.9e-39 134.1 0.0 7.2e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK58872.1 - 2.6e-34 118.8 0.1 4.3e-34 118.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK58873.1 - 0.00014 20.8 0.0 0.00015 20.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metal_resist PF13801.6 KIK58873.1 - 0.16 12.2 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Plavaka PF18759.1 KIK58877.1 - 4.3e-44 151.1 1.0 2.4e-22 79.6 0.1 2.0 1 1 1 2 2 2 2 Plavaka transposase DUF515 PF04415.12 KIK58878.1 - 7.4 4.8 8.0 8.6 4.6 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Peptidase_S49_N PF08496.10 KIK58879.1 - 0.00033 20.8 0.8 0.00064 19.8 0.8 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal KASH_CCD PF14662.6 KIK58879.1 - 0.0047 16.8 7.8 0.0071 16.2 7.8 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KIK58879.1 - 0.0056 17.2 4.7 0.0079 16.7 4.7 1.2 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KIK58879.1 - 0.025 13.5 8.5 0.039 12.8 8.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KIK58879.1 - 0.048 13.7 11.6 0.94 9.5 2.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KIK58879.1 - 0.11 11.8 3.9 0.21 10.9 3.9 1.4 1 0 0 1 1 1 0 FAM76 protein Bacillus_HBL PF05791.11 KIK58879.1 - 0.13 12.1 1.9 0.21 11.4 1.9 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 KIK58879.1 - 0.14 12.3 1.0 0.25 11.5 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KIK58879.1 - 0.16 11.4 8.5 0.22 10.9 8.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ATG19_autophagy PF12744.7 KIK58879.1 - 0.17 11.0 1.4 0.29 10.3 1.4 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding YbhQ PF11076.8 KIK58879.1 - 0.24 11.4 2.7 0.68 10.0 2.7 1.8 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ PKcGMP_CC PF16808.5 KIK58879.1 - 0.4 10.6 11.7 0.36 10.7 0.9 2.9 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran_Xtn PF12848.7 KIK58879.1 - 0.45 10.6 4.8 0.93 9.6 4.8 1.4 1 0 0 1 1 1 0 ABC transporter DUF724 PF05266.14 KIK58879.1 - 0.47 10.3 6.1 0.78 9.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Spc34 PF08657.10 KIK58879.1 - 0.64 9.8 4.5 1.1 9.0 4.5 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 ADIP PF11559.8 KIK58879.1 - 1.1 9.3 7.3 2.4 8.2 6.9 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 KIK58879.1 - 1.1 9.2 12.2 0.076 13.0 3.3 2.6 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 KIK58879.1 - 1.2 8.4 10.1 0.27 10.5 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 KIK58879.1 - 1.5 9.2 7.8 3.8 7.8 7.1 2.1 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) XLF PF09302.11 KIK58879.1 - 1.8 8.7 6.2 13 5.9 1.2 2.3 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component SlyX PF04102.12 KIK58879.1 - 2 9.1 8.7 7.9 7.2 5.0 2.7 1 1 2 3 3 3 0 SlyX Atg14 PF10186.9 KIK58879.1 - 2.1 7.3 7.2 4.1 6.4 7.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 KIK58879.1 - 2.7 8.1 7.3 1.6 8.9 1.0 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Csm1_N PF18504.1 KIK58879.1 - 4.4 7.7 10.7 4.7 7.6 0.9 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF327 PF03885.13 KIK58880.1 - 0.0088 16.0 0.5 0.015 15.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF327) DUF848 PF05852.11 KIK58880.1 - 0.017 15.3 0.5 0.032 14.4 0.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Na_trans_assoc PF06512.13 KIK58882.1 - 0.035 14.4 4.9 0.042 14.1 4.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Pacs-1 PF10254.9 KIK58882.1 - 0.28 10.1 0.6 0.33 9.9 0.6 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Zip PF02535.22 KIK58882.1 - 0.42 9.8 0.8 0.49 9.6 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pyr_redox_3 PF13738.6 KIK58883.1 - 0.0066 15.7 0.0 0.58 9.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK58883.1 - 0.071 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK58883.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BAR_3 PF16746.5 KIK58886.1 - 0.0018 18.1 2.3 0.073 12.8 0.8 2.2 2 0 0 2 2 2 2 BAR domain of APPL family Wx5_PLAF3D7 PF09688.10 KIK58886.1 - 0.081 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) DUF4618 PF15397.6 KIK58886.1 - 0.093 12.1 3.3 0.056 12.9 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Peptidase_S49_N PF08496.10 KIK58887.1 - 0.0039 17.3 0.2 0.0063 16.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK58887.1 - 0.026 13.4 5.8 0.036 12.9 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KIK58887.1 - 0.026 14.3 0.6 0.081 12.7 0.7 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FAM76 PF16046.5 KIK58887.1 - 0.038 13.4 1.2 0.056 12.8 1.2 1.2 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 KIK58887.1 - 0.06 13.4 9.7 0.77 9.8 1.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KIK58887.1 - 0.084 12.7 7.9 2.8 7.9 0.8 3.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_GP20 PF06810.11 KIK58887.1 - 0.66 9.8 5.7 3.9 7.3 0.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.8 KIK58887.1 - 0.7 10.0 7.0 8.5 6.4 5.3 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 KIK58887.1 - 0.7 9.9 8.5 0.28 11.2 2.2 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Csm1_N PF18504.1 KIK58887.1 - 0.86 10.0 9.9 1.5 9.2 1.0 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain ABC_tran_Xtn PF12848.7 KIK58887.1 - 1.2 9.3 4.0 2.2 8.4 4.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF641 PF04859.12 KIK58887.1 - 5.4 7.4 8.6 2.8 8.3 0.8 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.12 KIK58888.1 - 0.0062 16.6 1.0 0.0062 16.6 1.0 3.8 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein DUF2647 PF10839.8 KIK58888.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) RGCC PF15151.6 KIK58888.1 - 0.092 13.0 0.1 0.092 13.0 0.1 2.8 2 1 0 2 2 2 0 Response gene to complement 32 protein family FPP PF05911.11 KIK58888.1 - 0.58 8.3 29.4 0.01 14.1 20.8 1.9 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil IATP PF04568.12 KIK58888.1 - 6.2 7.3 8.4 0.55 10.7 2.4 2.3 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP AAA_13 PF13166.6 KIK58890.1 - 0.00066 18.5 4.6 0.00075 18.3 4.6 1.0 1 0 0 1 1 1 1 AAA domain BAR_2 PF10455.9 KIK58890.1 - 0.0031 16.7 3.9 0.0034 16.6 3.9 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF489 PF04356.12 KIK58890.1 - 0.017 15.2 0.3 0.019 15.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Gp-FAR-1 PF05823.12 KIK58890.1 - 0.017 15.4 3.1 0.074 13.4 2.8 1.9 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Csm1_N PF18504.1 KIK58890.1 - 0.049 14.0 2.6 0.049 14.0 2.6 2.5 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF3450 PF11932.8 KIK58890.1 - 0.054 12.8 4.4 0.062 12.6 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cnn_1N PF07989.11 KIK58890.1 - 0.054 13.6 11.1 6.7 7.0 11.1 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Occludin_ELL PF07303.13 KIK58890.1 - 0.077 13.7 2.4 0.091 13.5 1.4 1.5 1 1 1 2 2 2 0 Occludin homology domain FAM76 PF16046.5 KIK58890.1 - 0.083 12.2 5.5 0.1 11.9 5.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4472 PF14739.6 KIK58890.1 - 0.092 13.5 6.4 0.12 13.1 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) CP12 PF02672.15 KIK58890.1 - 0.095 13.5 1.5 7.9 7.3 0.2 2.2 2 0 0 2 2 2 0 CP12 domain PCRF PF03462.18 KIK58890.1 - 0.14 12.0 3.6 0.16 11.8 3.6 1.1 1 0 0 1 1 1 0 PCRF domain DUF948 PF06103.11 KIK58890.1 - 0.18 12.1 3.5 0.13 12.5 0.7 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mac PF12464.8 KIK58890.1 - 0.19 12.0 1.2 0.24 11.6 0.1 1.8 2 1 0 2 2 2 0 Maltose acetyltransferase ArAE_2_N PF10337.9 KIK58890.1 - 0.76 8.7 2.9 0.85 8.6 2.9 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Arm-DNA-bind_5 PF17293.2 KIK58890.1 - 0.95 9.9 6.6 4.4 7.8 6.6 1.9 1 1 0 1 1 1 0 Arm DNA-binding domain TolA_bind_tri PF16331.5 KIK58890.1 - 2.3 8.3 10.8 4.8 7.3 10.8 1.5 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF16 PF01519.16 KIK58890.1 - 4.9 7.7 10.0 23 5.5 10.0 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 Retrotrans_gag PF03732.17 KIK58891.1 - 1.3e-07 31.7 0.0 3.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK58891.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Cast PF10174.9 KIK58893.1 - 0.00018 19.9 7.3 0.00023 19.5 7.3 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Fez1 PF06818.15 KIK58893.1 - 0.0052 17.3 8.7 0.0084 16.6 8.7 1.3 1 0 0 1 1 1 1 Fez1 HMMR_N PF15905.5 KIK58893.1 - 0.017 14.7 8.4 0.029 13.9 8.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK58893.1 - 0.026 13.4 11.7 0.04 12.8 11.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KIK58893.1 - 0.043 13.7 1.1 0.11 12.3 1.3 1.6 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) KASH_CCD PF14662.6 KIK58893.1 - 0.053 13.4 10.4 0.091 12.6 10.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 KIK58893.1 - 0.06 13.3 13.8 0.4 10.7 6.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Peptidase_S49_N PF08496.10 KIK58893.1 - 0.11 12.6 2.8 0.064 13.3 0.8 1.6 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Spc42p PF11544.8 KIK58893.1 - 0.21 11.6 1.6 13 5.9 0.0 2.9 2 1 1 3 3 3 0 Spindle pole body component Spc42p DUF4503 PF14951.6 KIK58893.1 - 0.24 9.8 1.8 0.4 9.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF4201 PF13870.6 KIK58893.1 - 0.3 10.8 8.0 1.2 8.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Csm1_N PF18504.1 KIK58893.1 - 0.37 11.2 13.6 0.68 10.3 4.6 2.6 1 1 0 2 2 2 0 Csm1 N-terminal domain ADIP PF11559.8 KIK58893.1 - 0.46 10.6 13.9 1.7 8.7 2.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIK58893.1 - 0.57 9.5 8.0 0.84 8.9 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KIK58893.1 - 0.82 9.9 19.2 1.2 9.3 4.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 KIK58893.1 - 1.3 9.4 8.8 0.62 10.4 2.4 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3391 PF11871.8 KIK58893.1 - 1.3 9.5 5.2 2.7 8.6 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) PKcGMP_CC PF16808.5 KIK58893.1 - 1.6 8.7 10.8 3.4 7.6 0.7 3.5 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec2p PF06428.11 KIK58893.1 - 3 7.9 11.7 0.33 11.0 1.4 2.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p BRE1 PF08647.11 KIK58893.1 - 4.8 7.3 12.4 5.5 7.1 4.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 KIK58893.1 - 8.6 6.1 11.6 4.7 7.0 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 KIK58893.1 - 8.8 6.9 22.3 2 8.9 6.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Troponin PF00992.20 KIK58893.1 - 9 6.6 11.5 2.4 8.4 3.2 2.3 1 1 1 2 2 2 0 Troponin 5-FTHF_cyc-lig PF01812.20 KIK58894.1 - 2.8e-17 63.2 0.0 3.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF4919 PF16266.5 KIK58896.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) HR1 PF02185.16 KIK58897.1 - 2.6 8.2 4.6 0.74 10.0 1.2 1.7 2 0 0 2 2 2 0 Hr1 repeat HMMR_N PF15905.5 KIK58898.1 - 0.0083 15.6 4.6 0.013 15.0 4.6 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 KIK58898.1 - 0.035 14.6 3.9 0.056 13.9 3.9 1.2 1 0 0 1 1 1 0 Fez1 APG6_N PF17675.1 KIK58898.1 - 0.062 13.8 7.5 0.13 12.8 7.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 KIK58898.1 - 0.084 13.1 5.7 1.5 9.0 1.2 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 KIK58898.1 - 0.089 12.7 4.0 3.2 7.7 1.4 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KIK58898.1 - 0.09 11.6 5.9 0.15 10.9 5.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KIK58898.1 - 0.099 13.0 11.2 0.21 12.0 4.9 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Sec2p PF06428.11 KIK58898.1 - 0.1 12.5 6.0 0.095 12.7 0.6 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Transcrip_act PF04949.13 KIK58898.1 - 0.2 11.6 4.1 0.094 12.6 1.7 1.6 2 0 0 2 2 2 0 Transcriptional activator Phage_GP20 PF06810.11 KIK58898.1 - 0.6 9.9 3.4 4.2 7.2 0.1 2.2 1 1 0 2 2 2 0 Phage minor structural protein GP20 LRS4 PF10422.9 KIK58898.1 - 1.1 8.8 4.6 2 7.9 4.6 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMF_DNA_bd PF12329.8 KIK58898.1 - 1.3 9.1 6.9 0.73 9.9 1.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KIK58898.1 - 1.4 8.2 9.8 0.073 12.4 1.5 2.3 2 1 0 2 2 2 0 FAM76 protein ADIP PF11559.8 KIK58898.1 - 8 6.5 7.6 2.4 8.2 1.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-B_dimeris PF09026.10 KIK58900.1 - 0.032 14.6 1.4 0.032 14.6 1.4 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain E_Pc_C PF06752.12 KIK58901.1 - 0.42 10.7 3.8 0.56 10.3 3.8 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus CENP-Q PF13094.6 KIK58904.1 - 0.069 13.4 0.1 0.09 13.0 0.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Hydrolase_4 PF12146.8 KIK58905.1 - 8.9e-08 31.7 0.1 6e-06 25.7 0.1 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KIK58905.1 - 2.8e-07 30.4 0.0 4.3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KIK58905.1 - 3.1e-05 24.7 1.5 4.6e-05 24.1 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK58905.1 - 3.6e-05 23.5 0.0 0.0091 15.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KIK58905.1 - 0.008 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF4303 PF14136.6 KIK58909.1 - 0.23 11.2 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Arg_repressor PF01316.21 KIK58909.1 - 0.23 11.2 0.1 0.61 9.9 0.0 1.7 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain GTF2I PF02946.14 KIK58910.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.6 1 1 1 2 2 2 1 GTF2I-like repeat DUF2322 PF10084.9 KIK58911.1 - 0.02 14.9 0.3 0.093 12.8 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) HTH_18 PF12833.7 KIK58911.1 - 0.14 12.4 0.1 0.86 9.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_2 PF00891.18 KIK58916.1 - 7e-23 81.0 0.1 1.9e-22 79.6 0.0 1.6 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KIK58916.1 - 0.0044 16.9 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK58916.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KIK58916.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK58916.1 - 0.023 15.4 0.0 0.044 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK58916.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KIK58917.1 - 2.7e-10 40.3 0.2 4.3e-09 36.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK58917.1 - 0.00019 20.8 0.1 0.0012 18.2 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S49_N PF08496.10 KIK58918.1 - 0.0024 17.9 0.4 0.0051 16.9 0.4 1.5 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Transcrip_act PF04949.13 KIK58918.1 - 0.017 15.0 2.9 0.027 14.3 2.9 1.3 1 0 0 1 1 1 0 Transcriptional activator Spc7 PF08317.11 KIK58918.1 - 0.031 13.2 11.1 0.044 12.7 11.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec2p PF06428.11 KIK58918.1 - 0.04 13.9 6.2 0.038 14.0 2.3 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p KASH_CCD PF14662.6 KIK58918.1 - 0.17 11.7 9.6 0.32 10.8 9.6 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 KIK58918.1 - 0.37 10.8 14.3 2 8.5 2.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KIK58918.1 - 0.56 10.6 9.3 2.4 8.6 1.6 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Dzip-like_N PF13815.6 KIK58918.1 - 1.5 8.8 9.8 0.36 10.8 3.7 2.5 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal APG6_N PF17675.1 KIK58918.1 - 1.9 9.0 16.4 0.3 11.6 9.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 KIK58918.1 - 2.5 7.4 9.3 0.3 10.4 3.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) CC2-LZ PF16516.5 KIK58918.1 - 7.1 7.1 9.1 9.4 6.7 1.1 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF648 PF04890.13 KIK58919.1 - 0.0063 16.3 0.3 0.009 15.8 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF648) Sipho_Gp157 PF05565.11 KIK58919.1 - 0.027 14.5 0.5 0.048 13.7 0.5 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF745 PF05335.13 KIK58919.1 - 0.058 13.1 4.9 0.73 9.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 KIK58919.1 - 0.098 12.8 4.7 0.17 12.0 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TED_complement PF07678.14 KIK58919.1 - 0.12 11.4 0.2 0.16 11.0 0.2 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain Fib_alpha PF08702.10 KIK58919.1 - 1.3 9.2 4.3 4.1 7.6 0.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 KIK58919.1 - 7.4 7.3 9.3 11 6.8 1.7 3.1 1 1 2 3 3 3 0 SlyX Retrotrans_gag PF03732.17 KIK58921.1 - 4.4e-07 30.1 0.2 8.7e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK58921.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF648 PF04890.13 KIK58922.1 - 0.022 14.6 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF745 PF05335.13 KIK58922.1 - 0.086 12.6 3.6 1.1 9.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KIK58923.1 - 0.0098 14.8 9.2 0.0093 14.9 8.1 1.4 2 0 0 2 2 2 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KIK58923.1 - 0.07 13.1 10.4 0.28 11.2 6.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KIK58923.1 - 0.12 12.2 13.7 1.9 8.4 0.1 3.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bacillus_HBL PF05791.11 KIK58923.1 - 0.14 12.0 1.1 0.36 10.6 0.8 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) LRS4 PF10422.9 KIK58923.1 - 0.23 11.0 6.7 0.4 10.2 6.7 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fez1 PF06818.15 KIK58923.1 - 0.3 11.5 9.0 0.5 10.8 9.0 1.3 1 0 0 1 1 1 0 Fez1 DUF641 PF04859.12 KIK58923.1 - 0.48 10.8 5.5 0.91 9.9 2.9 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Latarcin PF10279.9 KIK58923.1 - 0.69 10.4 2.9 28 5.2 4.3 2.5 2 0 0 2 2 2 0 Latarcin precursor CC2-LZ PF16516.5 KIK58923.1 - 0.71 10.3 10.6 5.4 7.4 0.9 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Csm1_N PF18504.1 KIK58923.1 - 1.7 9.0 10.4 1.7 9.0 3.6 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain Retrotran_gag_2 PF14223.6 KIK58924.1 - 3.7e-14 52.6 0.3 4.8e-14 52.2 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1708 PF08101.11 KIK58925.1 - 0.00061 19.1 0.0 0.0054 15.9 0.0 2.4 3 1 0 3 3 3 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KIK58925.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.6 2 0 0 2 2 2 0 RhoGAP domain DUF3915 PF13054.6 KIK58925.1 - 0.017 15.1 3.1 0.051 13.6 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PET117 PF15786.5 KIK58925.1 - 1.1 9.6 8.3 3.6 7.9 8.3 1.9 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial SGL PF08450.12 KIK58926.1 - 4.7e-05 23.1 0.0 7.3e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIK58926.1 - 0.0073 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Arylesterase HAD_2 PF13419.6 KIK58927.1 - 3.6e-11 43.5 0.0 5.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK58927.1 - 1.9e-05 25.1 0.0 5.9e-05 23.5 0.0 1.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KIK58927.1 - 0.0036 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) Hydrolase_like PF13242.6 KIK58927.1 - 0.0045 17.0 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like MFS_1 PF07690.16 KIK58928.1 - 6.5e-34 117.4 49.2 6.5e-34 117.4 49.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK58928.1 - 3.5e-13 48.9 23.1 4.7e-13 48.4 23.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK58928.1 - 3.9e-09 35.9 11.6 3.9e-09 35.9 11.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.22 KIK58930.1 - 2.3e-68 231.0 0.0 2.8e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 KIK58931.1 - 5.4e-09 36.0 0.1 1.5e-08 34.5 0.1 1.6 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIK58931.1 - 5.7e-06 26.5 0.0 5.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Arylesterase Acyl-CoA_dh_M PF02770.19 KIK58932.1 - 0.031 14.5 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain FAD_binding_3 PF01494.19 KIK58933.1 - 1.8e-10 40.7 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK58933.1 - 6e-09 36.0 0.4 4.1e-08 33.2 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK58933.1 - 1.5e-08 34.8 0.0 4.1e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK58933.1 - 4e-07 29.5 0.0 6.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK58933.1 - 5.9e-07 29.0 0.2 4.1e-06 26.2 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK58933.1 - 4.3e-06 25.7 0.0 1.3e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIK58933.1 - 2.6e-05 24.7 0.1 0.00058 20.4 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK58933.1 - 0.00027 20.2 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIK58933.1 - 0.00048 19.5 0.1 0.0024 17.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK58933.1 - 0.0012 18.2 0.0 0.007 15.7 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIK58933.1 - 0.0048 16.5 0.2 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MCRA PF06100.11 KIK58933.1 - 0.013 14.3 0.1 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 MCRA family TrkA_N PF02254.18 KIK58933.1 - 0.015 15.6 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 KIK58933.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KIK58933.1 - 0.025 14.2 0.2 0.05 13.2 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KIK58933.1 - 0.049 12.7 0.1 0.092 11.8 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KIK58933.1 - 0.13 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK58933.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-MYND PF01753.18 KIK58934.1 - 2.2e-10 40.4 6.9 3.8e-10 39.7 6.9 1.4 1 0 0 1 1 1 1 MYND finger DUF1805 PF08827.11 KIK58934.1 - 0.036 14.4 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) zf-C6H2 PF15801.5 KIK58934.1 - 0.22 11.8 6.8 0.54 10.6 6.8 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Viral_helicase1 PF01443.18 KIK58936.1 - 0.0051 16.6 0.1 0.056 13.2 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KIK58936.1 - 0.014 14.5 0.4 0.21 10.7 0.1 2.5 1 1 1 2 2 2 0 PIF1-like helicase Ham1p_like PF01725.16 KIK58936.1 - 0.037 14.0 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Ham1 family UvrD_C_2 PF13538.6 KIK58936.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KIK58936.1 - 0.081 10.8 0.1 0.13 10.2 0.1 1.2 1 0 0 1 1 1 0 Helicase PIF1 PF05970.14 KIK58937.1 - 4.2e-11 42.6 0.0 5.1e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK58937.1 - 2.3e-08 34.0 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK58937.1 - 0.00012 22.5 0.0 0.00025 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KIK58937.1 - 0.028 13.4 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIK58937.1 - 0.028 14.8 0.0 0.032 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KIK58937.1 - 0.11 11.6 0.0 0.87 8.6 0.0 1.9 1 1 1 2 2 2 0 Type II/IV secretion system protein IIGP PF05049.13 KIK58937.1 - 0.14 11.2 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) CbiA PF01656.23 KIK58937.1 - 0.17 12.0 0.1 0.29 11.2 0.1 1.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KIK58937.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 KIK58938.1 - 0.0034 17.6 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.6 KIK58941.1 - 0.0062 16.9 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KIK58941.1 - 0.018 15.1 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK58941.1 - 0.037 14.3 0.1 0.24 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK58941.1 - 0.1 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain HNF-1A_C PF04813.12 KIK58946.1 - 0.087 13.6 0.3 0.14 13.0 0.3 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Pyridoxal_deC PF00282.19 KIK58947.1 - 2.7e-24 85.6 0.0 3.6e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KIK58947.1 - 0.0003 20.1 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIK58947.1 - 0.0015 17.9 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIK58947.1 - 0.033 13.1 0.1 0.086 11.8 0.1 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Fib_alpha PF08702.10 KIK58948.1 - 3.9 7.6 7.6 17 5.6 2.0 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-T_C PF15511.6 KIK58949.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK58949.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK58949.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK58949.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK58949.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK58949.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3435 PF11917.8 KIK58950.1 - 0.13 11.2 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) AhpC-TSA PF00578.21 KIK58952.1 - 8.3e-36 122.6 0.0 1.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK58952.1 - 2.7e-14 53.1 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIK58952.1 - 4.8e-11 42.3 0.0 8.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KIK58952.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC KDZ PF18758.1 KIK58953.1 - 8.5e-46 156.3 0.0 1.9e-45 155.2 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK58955.1 - 2.3e-27 95.3 0.6 2.3e-27 95.3 0.6 1.7 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK58955.1 - 0.00014 22.0 0.5 0.00029 20.9 0.5 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Myb_DNA-binding PF00249.31 KIK58956.1 - 9.2e-38 128.2 4.4 8.4e-12 45.1 0.1 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK58956.1 - 3.9e-26 91.1 0.6 4.2e-13 49.3 0.2 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 KIK58956.1 - 0.00017 21.6 0.0 1 9.5 0.1 3.0 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KIK58956.1 - 0.00045 20.4 0.0 0.25 11.5 0.0 3.3 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 KIK58956.1 - 0.00087 19.1 0.0 1.8 8.5 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 KIK58956.1 - 0.0057 16.7 0.0 1.7 8.7 0.0 2.8 3 0 0 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 KIK58956.1 - 0.011 15.9 1.6 3.1 8.1 0.0 2.5 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Cauli_VI PF01693.16 KIK58959.1 - 9.3e-08 32.3 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Phosphoesterase PF04185.14 KIK58961.1 - 0.065 12.4 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoesterase family Voltage_CLC PF00654.20 KIK58963.1 - 0.046 13.0 6.7 0.06 12.6 6.7 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel DUF1700 PF08006.11 KIK58963.1 - 0.8 9.2 6.2 0.89 9.1 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Claudin_3 PF06653.11 KIK58963.1 - 0.91 9.4 10.6 0.18 11.7 5.3 2.0 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DDE_Tnp_4 PF13359.6 KIK58964.1 - 2.5e-08 33.7 0.1 1.2e-06 28.3 0.1 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease ATG16 PF08614.11 KIK58965.1 - 0.026 14.8 4.3 0.078 13.2 4.3 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Coat_F PF07875.12 KIK58965.1 - 0.038 14.2 1.1 0.15 12.4 0.2 2.3 2 0 0 2 2 2 0 Coat F domain Voltage_CLC PF00654.20 KIK58966.1 - 0.051 12.8 9.9 0.0088 15.3 4.6 1.9 2 0 0 2 2 2 0 Voltage gated chloride channel LapA_dom PF06305.11 KIK58966.1 - 0.64 9.9 6.3 0.56 10.1 3.1 2.7 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain Pro_isomerase PF00160.21 KIK58968.1 - 2.2e-47 161.3 0.1 2.4e-47 161.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMC_oxred_N PF00732.19 KIK58969.1 - 9.9e-63 212.2 0.0 1.3e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK58969.1 - 3.4e-37 128.2 0.0 5.9e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK58969.1 - 0.00016 21.8 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK58969.1 - 0.0044 16.1 0.1 0.0088 15.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KIK58969.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK58969.1 - 0.013 14.8 0.1 0.027 13.7 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK58969.1 - 0.019 14.6 0.0 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK58969.1 - 0.071 12.2 0.1 0.14 11.3 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain VipB PF05943.12 KIK58969.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath Trp_halogenase PF04820.14 KIK58969.1 - 0.14 11.0 0.2 0.47 9.3 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GST_N_3 PF13417.6 KIK58970.1 - 1.3e-11 44.8 0.4 6.1e-11 42.6 0.4 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK58970.1 - 3.1e-11 43.4 0.0 6.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK58970.1 - 1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK58970.1 - 0.00018 21.7 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK58970.1 - 0.064 13.4 0.0 0.2 11.9 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GMC_oxred_N PF00732.19 KIK58972.1 - 6.6e-63 212.8 0.0 8.2e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK58972.1 - 9.6e-39 133.2 0.0 1.7e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK58972.1 - 0.00041 20.5 0.1 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK58972.1 - 0.0034 16.5 0.0 0.0091 15.1 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KIK58972.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK58972.1 - 0.01 15.5 0.0 0.057 13.0 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK58972.1 - 0.014 14.6 0.1 0.049 12.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK58972.1 - 0.054 12.6 0.1 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain VipB PF05943.12 KIK58972.1 - 0.18 10.6 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath Trp_halogenase PF04820.14 KIK58972.1 - 0.19 10.6 0.2 0.48 9.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase BTB PF00651.31 KIK58973.1 - 0.0039 17.4 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain GMC_oxred_N PF00732.19 KIK58974.1 - 1.2e-60 205.4 0.0 1.7e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK58974.1 - 1.7e-37 129.1 0.0 2.7e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Aldo_ket_red PF00248.21 KIK58975.1 - 9.5e-68 228.5 0.0 1.1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IBR PF01485.21 KIK58976.1 - 1.9e-15 56.8 31.9 1.8e-08 34.5 9.9 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIK58976.1 - 7.5e-07 29.1 7.5 7.5e-07 29.1 7.5 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK58976.1 - 5.8e-06 26.4 6.8 5.8e-06 26.4 6.8 3.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIK58976.1 - 9.6e-05 22.2 5.3 9.6e-05 22.2 5.3 3.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK58976.1 - 0.00019 21.2 4.4 0.00019 21.2 4.4 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK58976.1 - 0.00044 20.0 4.9 0.00044 20.0 4.9 4.1 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK58976.1 - 0.00046 20.5 5.7 0.00046 20.5 5.7 4.0 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KIK58976.1 - 0.0077 16.2 6.2 0.0077 16.2 6.2 4.1 3 1 1 4 4 4 1 zinc-RING finger domain GMC_oxred_N PF00732.19 KIK58977.1 - 1.8e-61 208.1 0.0 2.3e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK58977.1 - 8.9e-34 117.1 0.0 1.5e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK58977.1 - 0.0004 20.6 0.0 0.0095 16.1 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK58977.1 - 0.00085 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK58977.1 - 0.0014 17.9 0.0 0.16 11.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK58977.1 - 0.0016 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIK58977.1 - 0.0057 15.8 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK58977.1 - 0.027 14.1 0.0 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK58977.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KIK58977.1 - 0.17 11.1 0.0 0.77 8.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KIK58978.1 - 9.4e-70 235.1 0.0 1.1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OPT PF03169.15 KIK58979.1 - 1.6e-185 618.3 62.0 1.4e-184 615.2 62.0 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.20 KIK58979.1 - 4.4 6.8 5.4 0.58 9.7 0.6 2.0 2 0 0 2 2 2 0 E1-E2 ATPase adh_short_C2 PF13561.6 KIK58980.1 - 5.1e-58 196.4 1.1 6.3e-58 196.1 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK58980.1 - 7.9e-53 178.8 1.2 7.9e-53 178.8 1.2 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK58980.1 - 1.5e-10 41.2 0.7 2.2e-10 40.8 0.7 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KIK58980.1 - 0.016 15.3 0.3 0.047 13.8 0.3 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIK58980.1 - 0.048 13.5 0.1 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KIK58980.1 - 0.093 12.2 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KIK58981.1 - 3.4e-61 206.8 0.3 3.9e-61 206.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK58981.1 - 2.4e-55 187.0 0.2 2.4e-55 187.0 0.2 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK58981.1 - 1.5e-09 38.0 0.2 2.2e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK58981.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK58981.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KIK58981.1 - 0.024 14.5 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2247 PF10004.9 KIK58981.1 - 0.056 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Ldh_1_N PF00056.23 KIK58981.1 - 0.083 13.0 0.4 0.21 11.7 0.4 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KIK58982.1 - 5.9e-63 212.6 0.4 7.1e-63 212.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK58982.1 - 4.7e-55 186.1 1.4 4.7e-55 186.1 1.4 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK58982.1 - 6.3e-12 45.8 1.2 9.1e-12 45.2 1.2 1.2 1 0 0 1 1 1 1 KR domain HU-HIG PF18291.1 KIK58982.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif YcgL PF05166.13 KIK58982.1 - 0.059 13.7 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 YcgL domain adh_short_C2 PF13561.6 KIK58983.1 - 7.6e-65 218.7 0.2 9.2e-65 218.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK58983.1 - 8.4e-56 188.5 0.8 8.4e-56 188.5 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK58983.1 - 2.8e-11 43.7 0.4 3.9e-11 43.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK58983.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YcgL PF05166.13 KIK58983.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 YcgL domain adh_short_C2 PF13561.6 KIK58984.1 - 6.2e-64 215.8 0.2 7.5e-64 215.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK58984.1 - 4.9e-54 182.7 0.7 6e-54 182.5 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK58984.1 - 2.5e-08 34.0 0.8 3.5e-08 33.6 0.8 1.3 1 0 0 1 1 1 1 KR domain YcgL PF05166.13 KIK58984.1 - 0.19 12.1 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 YcgL domain Inositol_P PF00459.25 KIK58985.1 - 1.5e-55 188.6 0.1 5.2e-55 186.9 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family PilP PF04351.13 KIK58985.1 - 0.11 12.5 0.1 0.55 10.2 0.1 1.9 2 0 0 2 2 2 0 Pilus assembly protein, PilP Pyridoxal_deC PF00282.19 KIK58986.1 - 7.3e-20 71.0 0.0 4e-14 52.1 0.0 3.2 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KIK58986.1 - 0.025 13.9 0.0 0.051 12.8 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.32 KIK58987.1 - 8.1e-123 396.8 50.2 2.3e-10 40.9 0.0 12.6 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58987.1 - 1.4e-41 140.7 4.8 0.0057 16.9 0.0 11.9 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58987.1 - 3.1e-27 95.4 18.1 0.077 11.9 0.1 11.9 1 1 11 12 12 12 10 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK58987.1 - 2.7e-11 43.4 1.6 2.6 7.3 0.0 9.3 7 3 0 9 9 9 2 WD40-like domain PD40 PF07676.12 KIK58987.1 - 3.2e-11 42.8 21.2 5.5 7.0 0.0 10.2 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK58987.1 - 1.7e-09 36.9 8.3 4.7 5.7 0.1 9.0 5 2 5 10 10 10 2 Nucleoporin Nup120/160 NACHT PF05729.12 KIK58987.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.6 KIK58987.1 - 1.3e-06 28.0 15.6 0.46 9.8 0.1 8.6 3 3 6 9 9 9 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK58987.1 - 8.8e-05 21.0 0.0 6.9 4.8 0.0 6.2 2 2 7 9 9 9 1 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK58987.1 - 0.00018 21.9 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Nucleoporin_N PF08801.11 KIK58987.1 - 0.00062 18.6 6.3 0.16 10.7 0.0 5.0 2 1 4 6 6 6 1 Nup133 N terminal like Me-amine-dh_H PF06433.11 KIK58987.1 - 0.017 14.0 0.0 27 3.5 0.0 4.2 2 2 3 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) WD40_3 PF15911.5 KIK58987.1 - 0.017 15.1 3.4 3.7e+02 1.2 0.0 7.8 11 0 0 11 11 10 0 WD domain, G-beta repeat DUF4279 PF14106.6 KIK58987.1 - 0.024 14.9 0.1 4.1 7.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) RNA_helicase PF00910.22 KIK58987.1 - 0.035 14.5 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIK58987.1 - 0.043 14.1 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK58987.1 - 0.05 12.8 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KIK58987.1 - 0.052 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK58987.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIK58987.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK58987.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 NTPase Chordopox_A13L PF05961.11 KIK58990.1 - 0.044 14.0 0.4 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Ntox33 PF15533.6 KIK58990.1 - 0.059 13.9 0.4 0.093 13.2 0.4 1.3 1 0 0 1 1 1 0 Bacterial toxin 33 DUF2749 PF10907.8 KIK58990.1 - 1.4 9.1 6.7 1.7 8.9 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) WD40 PF00400.32 KIK58991.1 - 2.3e-122 395.4 47.9 1.7e-10 41.3 0.0 17.3 17 0 0 17 17 17 16 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58991.1 - 9.3e-53 176.5 2.7 5.6e-05 23.4 0.0 15.6 1 1 15 16 16 16 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58991.1 - 3.8e-40 137.8 24.7 0.0059 15.6 0.0 15.0 3 3 10 15 15 15 13 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK58991.1 - 4.2e-21 74.4 21.0 0.0077 16.1 0.0 14.7 15 0 0 15 15 15 4 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK58991.1 - 2.7e-13 49.4 24.5 0.61 8.7 0.0 11.8 5 4 5 13 13 13 5 Nucleoporin Nup120/160 Gmad1 PF10647.9 KIK58991.1 - 1.5e-11 44.6 30.2 6.1e-07 29.4 4.6 8.2 3 2 3 7 7 7 3 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.11 KIK58991.1 - 1.8e-11 44.3 0.5 0.002 18.1 0.0 5.7 2 2 4 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK58991.1 - 7.4e-10 38.6 15.1 2.6 7.3 0.0 10.8 4 3 8 13 13 13 4 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KIK58991.1 - 2.2e-09 37.2 6.1 3.2 7.8 0.0 10.4 10 1 0 11 11 11 1 WD domain, G-beta repeat Me-amine-dh_H PF06433.11 KIK58991.1 - 1.1e-06 27.7 0.1 2.6 6.8 0.0 5.0 4 1 2 6 6 6 3 Methylamine dehydrogenase heavy chain (MADH) Peptidase_S9_N PF02897.15 KIK58991.1 - 4.2e-06 25.8 3.0 12 4.5 0.0 7.3 3 3 8 11 11 11 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK58991.1 - 2.6e-05 22.7 0.0 0.13 10.6 0.0 4.7 5 1 0 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF3748 PF12566.8 KIK58991.1 - 6.6e-05 22.9 1.7 31 4.5 0.0 7.7 9 4 1 11 11 9 0 Protein of unknown function (DUF3748) DPPIV_N PF00930.21 KIK58991.1 - 0.0001 21.2 4.3 0.82 8.4 0.1 6.8 5 4 2 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_like PF17005.5 KIK58991.1 - 0.00015 21.2 0.1 9.4 5.5 0.0 6.1 7 0 0 7 7 7 0 WD40-like domain IKI3 PF04762.12 KIK58991.1 - 0.00051 18.2 0.1 2 6.3 0.0 4.4 4 1 0 4 4 4 1 IKI3 family DpaA_N PF16924.5 KIK58991.1 - 0.029 14.5 0.0 54 3.9 0.0 5.3 5 2 3 8 8 8 0 Dipicolinate synthase subunit A N-terminal domain Cuticle_4 PF15955.5 KIK58991.1 - 0.11 13.2 2.1 2.7e+02 2.3 0.0 6.4 7 1 1 8 8 7 0 Cuticle protein PQQ_2 PF13360.6 KIK58991.1 - 0.16 11.5 29.8 3.5 7.2 4.7 6.7 1 1 3 4 4 4 0 PQQ-like domain TruB_C PF09142.11 KIK58991.1 - 0.63 9.9 2.4 50 3.8 0.0 5.1 8 0 0 8 8 7 0 tRNA Pseudouridine synthase II, C terminal DUF4596 PF15363.6 KIK58991.1 - 3.1 8.1 9.7 8.5 6.7 0.2 6.0 6 0 0 6 6 5 0 Domain of unknown function (DUF4596) WD40 PF00400.32 KIK58992.1 - 8.8e-22 77.0 5.4 1.3e-06 29.0 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.12 KIK58992.1 - 7.7e-10 38.9 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK58992.1 - 7.4e-07 28.9 0.3 1.6 8.8 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK58992.1 - 2.3e-06 27.8 0.0 0.049 13.9 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIK58992.1 - 0.00035 20.4 2.9 0.00091 19.0 2.8 1.9 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 KIK58992.1 - 0.0056 15.7 0.2 1.8 7.4 0.0 3.4 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NTPase_1 PF03266.15 KIK58992.1 - 0.0094 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 KIK58992.1 - 0.013 15.8 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK58992.1 - 0.023 13.9 0.2 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KIK58992.1 - 0.04 14.4 3.6 0.33 11.4 2.4 2.6 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK58992.1 - 0.04 14.3 0.2 0.14 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase TFIIIC_delta PF12657.7 KIK58992.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term AAA_18 PF13238.6 KIK58992.1 - 0.094 13.3 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RPW8 PF05659.11 KIK58992.1 - 0.13 12.0 0.5 0.4 10.4 0.2 1.9 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.32 KIK58994.1 - 4.4e-90 293.2 39.2 6.2e-10 39.5 0.1 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58994.1 - 2.5e-38 130.2 0.0 0.00019 21.7 0.0 10.8 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58994.1 - 1.3e-32 113.1 13.2 0.014 14.4 0.0 10.9 1 1 9 11 11 11 10 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK58994.1 - 9.1e-13 48.2 8.4 1.1 8.5 0.0 9.5 2 2 7 9 9 9 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK58994.1 - 1.5e-11 43.7 12.2 0.43 9.1 2.5 8.8 3 2 5 8 8 8 5 Nucleoporin Nup120/160 PD40 PF07676.12 KIK58994.1 - 3.8e-10 39.4 27.5 4.5 7.3 0.1 11.0 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK58994.1 - 9.7e-08 32.1 18.0 0.044 13.5 0.5 6.0 1 1 4 5 5 5 4 Lipoprotein LpqB beta-propeller domain Ret2_MD PF18528.1 KIK58994.1 - 0.00012 22.4 0.2 53 4.3 0.0 6.4 2 2 6 8 8 8 0 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40_3 PF15911.5 KIK58994.1 - 0.00074 19.5 3.0 1.7e+02 2.3 0.0 7.7 9 0 0 9 9 9 0 WD domain, G-beta repeat HARP PF07443.13 KIK58994.1 - 0.018 14.6 0.2 4.7 6.9 0.0 4.0 4 0 0 4 4 4 0 HepA-related protein (HARP) DUF727 PF05303.12 KIK58994.1 - 0.03 14.4 0.2 27 4.9 0.0 4.3 5 1 0 5 5 5 0 Protein of unknown function (DUF727) Big_3_5 PF16640.5 KIK58994.1 - 1.5 9.1 23.0 1.8 8.8 0.6 6.4 4 2 3 7 7 7 0 Bacterial Ig-like domain (group 3) WD40 PF00400.32 KIK58995.1 - 2e-74 243.6 46.2 1.3e-09 38.5 0.1 14.1 13 1 0 13 13 13 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58995.1 - 1.8e-29 101.9 2.8 0.019 15.2 0.0 9.3 2 1 7 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58995.1 - 4.9e-23 81.6 8.2 0.00082 18.4 0.0 9.9 3 3 4 9 9 9 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK58995.1 - 1.1e-12 47.5 17.2 4 7.5 0.0 12.3 13 0 0 13 13 13 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK58995.1 - 2e-08 33.9 4.0 0.98 8.7 0.0 7.0 3 1 3 7 7 7 2 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.12 KIK58995.1 - 7.8e-08 32.4 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KIK58995.1 - 5.3e-06 25.4 13.3 0.89 8.1 0.1 8.3 5 3 4 10 10 10 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK58995.1 - 0.00032 19.6 5.5 0.66 8.6 0.1 4.2 2 1 3 5 5 5 3 Nup133 N terminal like RNA_helicase PF00910.22 KIK58995.1 - 0.017 15.5 0.2 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Frtz PF11768.8 KIK58995.1 - 0.019 13.3 0.0 8.4 4.6 0.0 3.7 4 1 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK58995.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain WD40_3 PF15911.5 KIK58995.1 - 0.077 13.0 1.5 1.8e+02 2.2 0.1 5.3 7 0 0 7 7 7 0 WD domain, G-beta repeat AAA_23 PF13476.6 KIK58995.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TFIIIC_delta PF12657.7 KIK58995.1 - 0.21 11.5 6.1 1.8 8.5 0.1 4.0 4 1 1 5 5 5 0 Transcription factor IIIC subunit delta N-term Big_3_5 PF16640.5 KIK58995.1 - 0.31 11.2 4.0 5.4 7.3 0.4 3.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) rOmpB PF12334.8 KIK58995.1 - 0.68 9.4 6.8 11 5.4 0.5 3.5 1 1 2 3 3 3 0 Rickettsia outer membrane protein B WD40 PF00400.32 KIK58998.1 - 5.9e-118 381.4 49.3 1.2e-09 38.6 0.5 14.1 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK58998.1 - 2.1e-47 159.4 0.5 9.2e-05 22.7 0.0 13.5 1 1 12 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK58998.1 - 1.7e-42 145.5 19.0 0.00018 20.6 0.1 13.4 2 2 9 13 13 13 12 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK58998.1 - 1.6e-24 85.3 21.9 1.4 9.0 0.1 13.9 14 0 0 14 14 14 9 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK58998.1 - 5.1e-12 45.2 18.3 0.025 13.3 0.1 9.9 4 3 6 11 11 11 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK58998.1 - 2.1e-11 43.7 16.3 1.3 8.3 0.1 11.0 2 2 11 14 14 14 5 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK58998.1 - 8.2e-11 42.1 0.2 0.011 15.7 0.0 5.7 2 2 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A Peptidase_S9_N PF02897.15 KIK58998.1 - 5.5e-07 28.7 0.7 2.9 6.6 0.0 6.7 4 3 4 8 8 8 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK58998.1 - 9.7e-07 27.5 0.0 0.033 12.5 0.0 4.6 4 2 1 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 KIK58998.1 - 7.3e-06 25.9 2.6 3.5 7.7 0.0 7.7 8 0 0 8 8 8 1 WD domain, G-beta repeat IKI3 PF04762.12 KIK58998.1 - 0.00022 19.4 0.3 1.5 6.7 0.0 4.1 4 2 1 5 5 5 2 IKI3 family Ret2_MD PF18528.1 KIK58998.1 - 0.0016 18.8 0.3 83 3.7 0.0 6.5 5 4 5 10 10 10 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Me-amine-dh_H PF06433.11 KIK58998.1 - 0.0053 15.7 0.0 2.6 6.8 0.0 3.4 3 1 0 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) FLgD_tudor PF13861.6 KIK58998.1 - 0.052 13.8 0.1 1.3e+02 2.9 0.0 4.5 4 0 0 4 4 4 0 FlgD Tudor-like domain WD40_like PF17005.5 KIK58998.1 - 0.23 10.8 0.0 67 2.7 0.0 3.7 3 1 0 4 4 4 0 WD40-like domain NACHT PF05729.12 KIK58999.1 - 5.7e-06 26.3 0.0 7.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK58999.1 - 0.0036 17.2 0.0 0.0078 16.1 0.0 1.4 1 1 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KIK58999.1 - 0.0072 16.7 0.1 0.017 15.5 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_23 PF13476.6 KIK58999.1 - 0.026 15.0 0.0 0.029 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK58999.1 - 0.032 14.6 0.0 0.039 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KIK58999.1 - 0.036 14.6 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK58999.1 - 0.054 13.6 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK58999.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KIK58999.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KIK58999.1 - 0.078 13.2 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK58999.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 KIK58999.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK58999.1 - 0.15 11.1 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK58999.1 - 0.16 12.4 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK58999.1 - 0.22 12.0 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KIK58999.1 - 0.24 11.1 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK59002.1 - 1.5e-145 468.7 73.1 1.9e-10 41.1 0.0 22.1 22 1 0 22 22 20 19 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59002.1 - 5.5e-61 202.9 4.9 0.0046 17.2 0.0 19.6 2 2 17 20 20 20 15 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59002.1 - 8.6e-53 179.4 30.4 0.0031 16.5 0.0 19.5 4 4 13 19 19 19 17 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59002.1 - 2e-28 97.7 40.2 0.18 11.8 0.2 22.1 23 0 0 23 23 23 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK59002.1 - 6.8e-19 68.6 31.9 9e-06 25.6 3.7 9.8 2 2 6 9 9 9 5 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 KIK59002.1 - 1e-15 57.8 22.1 0.78 9.0 0.0 15.0 4 2 11 18 18 18 4 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK59002.1 - 1.2e-13 51.4 4.9 0.0032 17.4 0.0 6.9 5 1 2 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK59002.1 - 3.4e-11 42.5 30.1 1.6 7.2 0.1 14.0 5 5 10 16 16 16 4 Nucleoporin Nup120/160 DUF5046 PF16465.5 KIK59002.1 - 6e-08 32.4 2.9 2 7.8 0.0 7.7 5 2 2 9 9 9 1 Domain of unknown function (DUF5046) Frtz PF11768.8 KIK59002.1 - 2e-05 23.1 0.0 0.97 7.7 0.0 5.8 4 2 5 10 10 10 1 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK59002.1 - 0.00014 20.8 1.5 15 4.2 0.0 6.6 5 2 1 7 7 7 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK59002.1 - 0.00039 20.2 2.8 18 5.5 0.0 7.1 7 0 0 7 7 7 0 PQQ enzyme repeat DUF3748 PF12566.8 KIK59002.1 - 0.00057 19.8 3.5 63 3.6 0.0 8.4 8 5 3 11 11 9 0 Protein of unknown function (DUF3748) Ret2_MD PF18528.1 KIK59002.1 - 0.0018 18.6 2.0 23 5.5 0.0 7.9 6 4 6 12 12 12 0 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40_3 PF15911.5 KIK59002.1 - 0.0054 16.7 14.5 97 3.1 0.0 10.4 14 0 0 14 14 12 0 WD domain, G-beta repeat Me-amine-dh_H PF06433.11 KIK59002.1 - 0.0087 15.0 0.1 24 3.6 0.0 4.7 3 1 1 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) WD40_like PF17005.5 KIK59002.1 - 0.01 15.2 1.3 51 3.0 0.1 5.9 6 1 1 7 7 7 0 WD40-like domain DUF1207 PF06727.11 KIK59002.1 - 0.039 12.9 0.3 0.36 9.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1207) DUF1652 PF07865.11 KIK59002.1 - 0.12 12.2 0.0 8 6.4 0.0 4.2 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) UN_NPL4 PF11543.8 KIK59002.1 - 0.41 11.2 2.7 2.6e+02 2.2 0.0 5.8 8 0 0 8 8 5 0 Nuclear pore localisation protein NPL4 DUF4072 PF13284.6 KIK59002.1 - 5 7.7 10.8 15 6.1 0.0 6.9 11 0 0 11 11 8 0 Domain of unknown function (DUF4072) NACHT PF05729.12 KIK59003.1 - 1.7e-06 28.0 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK59003.1 - 0.0023 17.8 0.0 0.0046 16.9 0.0 1.4 1 1 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KIK59003.1 - 0.0041 17.5 0.0 0.0075 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KIK59003.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK59003.1 - 0.027 14.7 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK59003.1 - 0.038 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK59003.1 - 0.04 14.5 0.0 0.05 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK59003.1 - 0.046 14.1 0.0 0.05 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK59003.1 - 0.056 12.6 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 KIK59003.1 - 0.065 13.7 0.0 0.071 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK59003.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK59003.1 - 0.079 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 KIK59003.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KIK59003.1 - 0.098 13.1 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KIK59003.1 - 0.2 11.3 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase WD40 PF00400.32 KIK59005.1 - 2.5e-91 297.1 39.3 8.5e-10 39.1 0.1 11.4 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59005.1 - 1.9e-37 127.4 0.1 0.00018 21.7 0.0 10.5 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59005.1 - 4.3e-32 111.4 12.8 0.0029 16.6 0.0 10.9 1 1 6 11 11 11 10 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK59005.1 - 2.4e-12 46.8 9.1 0.68 9.2 0.0 9.5 2 2 8 10 10 10 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK59005.1 - 1e-11 44.2 13.6 0.13 10.9 1.3 8.7 3 2 5 9 9 9 6 Nucleoporin Nup120/160 PD40 PF07676.12 KIK59005.1 - 1.1e-10 41.2 25.0 2.9 7.9 0.1 10.9 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 KIK59005.1 - 0.0088 16.0 4.4 2.4e+02 1.8 0.0 7.3 9 0 0 9 9 9 0 WD domain, G-beta repeat PsbN PF02468.15 KIK59005.1 - 0.03 14.2 0.5 1.1 9.2 0.0 3.4 4 0 0 4 4 4 0 Photosystem II reaction centre N protein (psbN) WD40_like PF17005.5 KIK59005.1 - 0.28 10.5 0.1 46 3.2 0.0 3.7 5 0 0 5 5 5 0 WD40-like domain Big_3_5 PF16640.5 KIK59005.1 - 4.3 7.6 17.0 5 7.4 0.3 5.8 4 2 3 7 7 7 0 Bacterial Ig-like domain (group 3) WD40 PF00400.32 KIK59006.1 - 3.4e-53 176.4 35.3 2.5e-07 31.2 0.1 11.6 11 1 1 12 12 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59006.1 - 5.5e-23 81.1 0.1 0.033 14.5 0.0 8.4 1 1 7 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59006.1 - 6.9e-18 64.7 4.2 0.00065 18.7 0.0 8.8 1 1 8 11 11 11 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59006.1 - 3.3e-15 55.6 12.9 0.004 17.0 0.0 10.5 12 0 0 12 12 12 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK59006.1 - 8.5e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Gmad1 PF10647.9 KIK59006.1 - 7.1e-06 25.9 13.1 0.18 11.5 2.1 6.4 2 2 2 4 4 4 3 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 KIK59006.1 - 2.1e-05 24.0 3.5 0.79 9.0 0.0 5.9 2 1 4 7 7 7 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KIK59006.1 - 0.00041 19.2 3.4 0.16 10.6 1.1 3.8 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 KIK59006.1 - 0.0023 16.6 4.7 4.4 5.8 0.1 5.8 4 3 2 7 7 7 1 Nucleoporin Nup120/160 WD40_3 PF15911.5 KIK59006.1 - 0.011 15.8 3.5 1.4e+02 2.6 0.1 6.6 8 0 0 8 8 8 0 WD domain, G-beta repeat RNA_helicase PF00910.22 KIK59006.1 - 0.011 16.1 0.1 0.093 13.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KIK59006.1 - 0.012 16.1 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KIK59006.1 - 0.049 14.1 0.7 0.15 12.5 0.1 1.9 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK59006.1 - 0.053 12.7 0.0 0.6 9.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Ribosomal_L4 PF00573.22 KIK59007.1 - 0.18 11.5 1.6 0.19 11.4 1.6 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family RRM_1 PF00076.22 KIK59007.1 - 0.2 11.5 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arena_ncap_C PF17290.2 KIK59008.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain WD40 PF00400.32 KIK59009.1 - 3.3e-105 341.0 41.2 9.6e-11 42.1 0.3 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59009.1 - 1.1e-42 144.2 2.0 0.023 15.0 0.0 11.0 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59009.1 - 1.7e-39 135.7 12.4 0.012 14.6 0.0 11.0 3 2 6 11 11 11 11 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK59009.1 - 6.2e-17 61.4 18.7 0.041 12.5 0.2 10.7 3 2 8 11 11 11 7 Nucleoporin Nup120/160 PD40 PF07676.12 KIK59009.1 - 1.1e-16 60.3 18.9 1.2 9.1 0.1 11.1 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK59009.1 - 5.9e-14 52.1 16.3 0.23 10.8 0.0 10.1 1 1 9 11 11 11 5 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK59009.1 - 3.3e-11 43.5 0.5 0.00016 21.6 0.0 5.2 1 1 5 6 6 6 3 Eukaryotic translation initiation factor eIF2A Peptidase_S9_N PF02897.15 KIK59009.1 - 1.6e-07 30.5 5.6 0.52 9.0 0.0 7.6 1 1 5 8 8 8 2 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40_3 PF15911.5 KIK59009.1 - 1.5e-06 28.1 2.5 2.8 8.0 0.0 8.3 11 0 0 11 11 11 1 WD domain, G-beta repeat Frtz PF11768.8 KIK59009.1 - 1.1e-05 24.0 0.0 0.32 9.2 0.0 5.0 3 1 2 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK59009.1 - 9.9e-05 21.8 0.0 0.74 9.1 0.0 4.8 4 2 1 6 6 6 1 WD40-like domain Me-amine-dh_H PF06433.11 KIK59009.1 - 0.0035 16.3 0.2 7.5 5.3 0.0 4.1 2 2 2 5 5 5 1 Methylamine dehydrogenase heavy chain (MADH) Ret2_MD PF18528.1 KIK59009.1 - 0.0057 17.0 0.3 48 4.4 0.0 5.8 2 2 7 9 9 9 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Glyoxalase_4 PF13669.6 KIK59009.1 - 0.009 16.3 0.1 12 6.3 0.0 3.8 2 2 1 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UN_NPL4 PF11543.8 KIK59009.1 - 0.074 13.5 3.5 59 4.2 0.0 6.1 10 0 0 10 10 9 0 Nuclear pore localisation protein NPL4 Phi29_Phage_SSB PF17427.2 KIK59009.1 - 0.08 13.1 0.1 10 6.3 0.0 4.1 3 1 2 6 6 6 0 Phage Single-stranded DNA-binding protein CN_hydrolase PF00795.22 KIK59009.1 - 0.31 10.3 5.1 7.6 5.8 0.0 4.6 5 1 1 6 6 6 0 Carbon-nitrogen hydrolase DUF5570 PF17731.1 KIK59009.1 - 5 7.2 30.2 61 3.7 0.1 9.3 2 1 5 11 11 11 0 Family of unknown function (DUF5570) NACHT PF05729.12 KIK59010.1 - 9.6e-06 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK59010.1 - 0.0035 17.3 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KIK59010.1 - 0.0091 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_23 PF13476.6 KIK59010.1 - 0.027 15.0 0.0 0.03 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK59010.1 - 0.042 14.4 0.0 0.058 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK59010.1 - 0.052 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIK59010.1 - 0.057 13.6 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK59010.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KIK59010.1 - 0.079 13.3 0.0 0.091 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK59010.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KIK59010.1 - 0.12 12.7 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK59010.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK59010.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK59010.1 - 0.2 12.1 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK59010.1 - 0.23 12.0 0.0 0.37 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.32 KIK59011.1 - 1.7e-45 152.0 19.1 3.6e-10 40.2 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59011.1 - 1.2e-20 73.6 0.0 0.022 15.0 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59011.1 - 1e-17 64.2 6.3 0.00031 19.8 0.0 6.0 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59011.1 - 1e-11 44.4 5.3 3.2 7.8 0.0 6.3 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59011.1 - 3e-05 22.9 4.7 0.0084 14.8 0.5 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK59011.1 - 0.0045 16.4 7.2 19 4.5 0.0 5.4 2 1 3 6 6 6 0 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KIK59011.1 - 0.013 15.5 0.6 6.4 6.9 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat UN_NPL4 PF11543.8 KIK59011.1 - 0.12 12.8 0.7 37 4.9 0.0 4.0 4 1 1 5 5 5 0 Nuclear pore localisation protein NPL4 Attacin_N PF03768.15 KIK59011.1 - 0.46 10.6 2.5 5.7 7.2 0.0 3.5 3 1 0 3 3 3 0 Attacin, N-terminal region FLgD_tudor PF13861.6 KIK59011.1 - 0.68 10.2 4.3 0.69 10.2 0.4 2.9 3 1 0 3 3 3 0 FlgD Tudor-like domain DUF5570 PF17731.1 KIK59011.1 - 0.89 9.7 8.1 50 4.0 0.1 4.4 3 1 2 5 5 5 0 Family of unknown function (DUF5570) Proteasome_A_N PF10584.9 KIK59011.1 - 1.1 9.0 17.9 10 5.9 0.2 6.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature p450 PF00067.22 KIK59012.1 - 2.2e-65 221.2 0.0 4.2e-65 220.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 CitMHS PF03600.16 KIK59012.1 - 0.067 12.4 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter DUF4516 PF14990.6 KIK59013.1 - 0.73 9.6 2.5 0.93 9.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) DUF2953 PF11167.8 KIK59013.1 - 1.1 9.3 4.6 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) DUF596 PF04591.12 KIK59014.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 DDOST_48kD PF03345.14 KIK59015.1 - 1.3e-113 380.0 0.0 1e-112 377.0 0.0 1.9 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta CcmD PF04995.14 KIK59016.1 - 0.011 15.8 1.4 0.011 15.8 1.4 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) NICE-1 PF15845.5 KIK59016.1 - 0.25 12.1 0.2 0.25 12.1 0.2 2.7 1 1 0 2 2 2 0 Cysteine-rich C-terminal 1 family DNA_pol_A_exo1 PF01612.20 KIK59019.1 - 2.7e-13 50.0 0.0 9.9e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease ADK PF00406.22 KIK59022.1 - 1.2e-57 194.3 0.0 1.4e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIK59022.1 - 1.9e-19 70.4 0.1 5.2e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KIK59022.1 - 1.7e-17 63.1 0.0 3.9e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIK59022.1 - 0.0049 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK59022.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SET PF00856.28 KIK59023.1 - 6e-13 49.5 0.1 3.2e-12 47.2 0.1 2.1 1 1 0 1 1 1 1 SET domain SET PF00856.28 KIK59024.1 - 2e-12 47.9 0.1 6.4e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 SET domain SET PF00856.28 KIK59025.1 - 2.1e-10 41.3 0.2 3.6e-09 37.2 0.2 2.3 1 1 0 1 1 1 1 SET domain F-box PF00646.33 KIK59026.1 - 1.2e-06 28.2 0.0 4e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK59026.1 - 3.2e-05 23.7 0.3 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIK59026.1 - 0.083 12.8 0.4 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 F-box F-box PF00646.33 KIK59027.1 - 4.6e-07 29.5 1.7 1.4e-06 28.0 0.0 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KIK59027.1 - 7.1e-06 25.8 0.0 7.1e-06 25.8 0.0 3.2 4 0 0 4 4 4 1 F-box-like F-box_4 PF15966.5 KIK59027.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.9 4 0 0 4 4 4 0 F-box PHD_4 PF16866.5 KIK59027.1 - 0.46 10.6 12.0 2.2 8.4 0.1 4.2 4 0 0 4 4 4 0 PHD-finger Rsm1 PF08600.10 KIK59027.1 - 0.74 10.0 3.1 1.6 8.9 0.6 2.9 3 0 0 3 3 3 0 Rsm1-like VCBS PF13517.6 KIK59028.1 - 1.2e-23 83.4 15.8 3.4e-09 37.2 1.2 5.9 3 3 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 KIK59028.1 - 0.0019 17.6 2.5 9.3 5.6 0.0 5.4 6 0 0 6 6 6 1 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 KIK59028.1 - 0.011 15.9 23.5 1.6 8.9 0.1 6.6 7 0 0 7 7 7 0 FG-GAP repeat Itfg2 PF15907.5 KIK59028.1 - 0.098 11.7 0.0 0.78 8.7 0.0 2.1 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Dockerin_1 PF00404.18 KIK59028.1 - 0.15 12.3 1.8 4.5 7.5 0.0 3.8 4 0 0 4 4 4 0 Dockerin type I domain DUF2724 PF10893.8 KIK59028.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) UDPG_MGDP_dh_N PF03721.14 KIK59029.1 - 9.5e-60 201.4 0.1 2.3e-59 200.1 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KIK59029.1 - 7.2e-35 119.6 0.1 1.7e-33 115.2 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KIK59029.1 - 5.9e-31 106.5 0.0 1.3e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 KIK59029.1 - 0.0031 18.0 0.0 3.3 8.3 0.0 3.2 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KIK59029.1 - 0.0033 17.4 0.3 3.6 7.6 0.1 2.7 2 1 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KIK59029.1 - 0.0041 17.4 0.1 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KIK59029.1 - 0.034 13.4 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIK59029.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIK59029.1 - 0.1 12.8 0.1 0.56 10.5 0.0 2.3 3 0 0 3 3 3 0 TrkA-N domain GFO_IDH_MocA PF01408.22 KIK59029.1 - 0.11 13.3 0.1 0.4 11.5 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold V_ATPase_I PF01496.19 KIK59030.1 - 0 1057.8 0.0 0 1057.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 KIK59030.1 - 3.6 8.3 5.9 4.4 8.0 2.0 2.8 3 0 0 3 3 3 0 SlyX IF4E PF01652.18 KIK59031.1 - 1.2e-49 168.2 0.0 1.8e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase_fungal PF17667.1 KIK59033.1 - 2.6e-17 62.7 0.0 3.1e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK59033.1 - 0.00035 20.0 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain VPDSG-CTERM PF18205.1 KIK59034.1 - 0.0012 18.6 2.3 0.0061 16.3 2.3 2.3 1 0 0 1 1 1 1 VPDSG-CTERM motif Amnionless PF14828.6 KIK59034.1 - 0.0024 16.8 1.9 0.0047 15.8 1.5 1.6 1 1 1 2 2 2 1 Amnionless SKG6 PF08693.10 KIK59034.1 - 0.0038 16.6 0.1 0.011 15.1 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ResB PF05140.14 KIK59034.1 - 0.01 14.6 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 ResB-like family CD34_antigen PF06365.12 KIK59034.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 CD34/Podocalyxin family HeLo PF14479.6 KIK59040.1 - 2.4e-31 109.2 0.1 3.3e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.8 KIK59040.1 - 0.0017 18.4 3.1 0.0032 17.5 0.6 2.7 3 1 0 3 3 3 1 Het-s 218-289 ABC_tran PF00005.27 KIK59042.1 - 8.1e-44 149.5 0.2 2.6e-21 76.6 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK59042.1 - 1.2e-17 64.7 1.7 2.3e-07 30.9 0.2 4.1 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK59042.1 - 1.2e-13 51.1 1.0 0.0024 17.3 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK59042.1 - 3.7e-08 33.0 0.2 0.0059 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KIK59042.1 - 1.3e-06 29.0 0.2 0.0043 17.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KIK59042.1 - 9.1e-06 25.9 0.0 0.0041 17.2 0.0 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KIK59042.1 - 1.2e-05 25.7 0.0 0.062 13.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KIK59042.1 - 2.5e-05 24.3 0.0 0.24 11.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK59042.1 - 4.6e-05 23.4 0.1 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KIK59042.1 - 5.1e-05 23.9 13.5 0.0049 17.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KIK59042.1 - 0.00011 22.5 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 KIK59042.1 - 0.00016 22.1 0.7 0.1 13.0 0.0 3.4 4 0 0 4 4 2 1 AAA ATPase domain AAA PF00004.29 KIK59042.1 - 0.00018 21.9 0.0 2.5 8.5 0.0 3.8 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Chromo PF00385.24 KIK59042.1 - 0.0002 21.2 0.5 0.00046 20.0 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 KIK59042.1 - 0.00027 21.2 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KIK59042.1 - 0.00052 20.0 0.6 0.6 10.0 0.1 2.8 2 1 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KIK59042.1 - 0.0006 20.0 0.0 2.1 8.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain HEAT_2 PF13646.6 KIK59042.1 - 0.00065 20.0 11.2 0.0088 16.4 0.2 3.5 3 1 0 3 3 2 1 HEAT repeats AAA_24 PF13479.6 KIK59042.1 - 0.0029 17.4 0.0 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KIK59042.1 - 0.0029 16.6 2.3 0.29 10.1 0.1 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 KIK59042.1 - 0.0032 17.7 0.1 1.9 8.8 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KIK59042.1 - 0.0033 17.0 0.3 3.1 7.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 KIK59042.1 - 0.0056 16.4 0.1 4.9 6.8 0.2 3.3 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KIK59042.1 - 0.0057 16.6 2.0 6.7 6.6 0.2 3.9 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KIK59042.1 - 0.0082 15.3 0.1 2.6 7.1 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KIK59042.1 - 0.012 14.9 0.2 4.1 6.5 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 KIK59042.1 - 0.017 15.3 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KIK59042.1 - 0.019 14.7 9.2 0.29 10.8 0.0 3.2 3 1 0 3 3 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KIK59042.1 - 0.026 14.2 3.1 4.1 7.0 0.0 4.2 4 1 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CLP1_P PF16575.5 KIK59042.1 - 0.038 13.8 0.1 12 5.7 0.0 3.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 KIK59042.1 - 0.046 13.6 0.1 7.5 6.4 0.0 3.0 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KIK59042.1 - 0.067 13.2 2.6 9.2 6.3 0.1 3.1 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4HB PF17947.1 KIK59042.1 - 0.076 13.1 0.4 0.28 11.2 0.0 2.2 2 0 0 2 2 1 0 Four helical bundle domain AAA_13 PF13166.6 KIK59042.1 - 0.088 11.4 3.6 1.8 7.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_27 PF13514.6 KIK59042.1 - 0.1 12.1 0.1 11 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain U3snoRNP10 PF12397.8 KIK59042.1 - 0.12 12.7 1.4 0.38 11.1 1.4 1.9 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Vac14_Fab1_bd PF12755.7 KIK59042.1 - 0.13 12.9 0.0 25 5.6 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region IstB_IS21 PF01695.17 KIK59042.1 - 0.14 11.9 0.1 42 3.8 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF3437 PF11919.8 KIK59042.1 - 0.15 12.0 0.2 1.4 8.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) cobW PF02492.19 KIK59042.1 - 0.16 11.6 2.3 11 5.6 0.1 3.5 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain HEAT_EZ PF13513.6 KIK59042.1 - 0.27 11.8 8.6 19 5.9 3.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat AAA_5 PF07728.14 KIK59042.1 - 0.87 9.6 4.4 13 5.8 0.1 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) HEAT PF02985.22 KIK59042.1 - 1.8 9.0 6.4 1e+02 3.6 0.0 4.8 5 0 0 5 5 3 0 HEAT repeat DUF596 PF04591.12 KIK59043.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 ECF_trnsprt PF12822.7 KIK59043.1 - 2.4 8.2 10.8 1.9e+02 2.1 10.8 2.4 1 1 0 1 1 1 0 ECF transporter, substrate-specific component MpPF26 PF07666.11 KIK59043.1 - 3.6 7.7 6.1 4.6 7.4 0.1 2.9 3 1 0 3 3 3 0 M penetrans paralogue family 26 4HBT PF03061.22 KIK59046.1 - 5.7e-11 42.6 0.0 8.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Lzipper-MIP1 PF14389.6 KIK59047.1 - 0.15 12.4 0.4 0.15 12.4 0.4 2.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Pkinase_fungal PF17667.1 KIK59048.1 - 4.1e-23 81.8 0.0 5.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK59048.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK59049.1 - 9.1e-23 80.7 0.1 1.1e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK59049.1 - 5.8e-06 25.9 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59049.1 - 0.027 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 KIK59049.1 - 0.055 13.4 0.7 0.077 12.9 0.7 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK59050.1 - 3.5e-20 72.2 0.0 4.5e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK59050.1 - 0.00046 19.6 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK59050.1 - 0.074 13.0 0.4 0.11 12.4 0.4 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK59050.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.7 KIK59052.1 - 0.0053 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF1691 PF07950.11 KIK59053.1 - 0.00014 22.5 3.2 0.0011 19.6 0.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) DUF979 PF06166.12 KIK59053.1 - 0.037 13.2 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) E1-E2_ATPase PF00122.20 KIK59054.1 - 2.1e-48 164.2 5.6 1e-47 162.0 2.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KIK59054.1 - 4.8e-20 72.7 0.0 3.9e-18 66.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIK59054.1 - 6e-20 71.7 19.7 3.6e-17 62.7 1.2 3.8 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KIK59054.1 - 6.6e-17 61.4 0.0 1.5e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIK59054.1 - 4.2e-16 58.4 0.0 1e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK59054.1 - 9.8e-05 22.2 0.5 0.014 15.1 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4181 PF13789.6 KIK59054.1 - 0.099 12.9 4.6 1.2 9.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF2269 PF10027.9 KIK59054.1 - 4.8 7.2 9.2 0.75 9.8 0.9 3.1 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) DUF4951 PF16309.5 KIK59055.1 - 0.075 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) DUF1772 PF08592.11 KIK59055.1 - 0.18 12.2 8.9 0.56 10.5 8.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Vma12 PF11712.8 KIK59056.1 - 1.1 9.3 6.9 0.24 11.4 0.4 2.4 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CBM_21 PF03370.13 KIK59057.1 - 5e-27 94.3 0.5 1e-26 93.3 0.5 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIK59057.1 - 1.3e-09 38.5 1.1 2.7e-09 37.5 1.1 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PLA2_B PF01735.18 KIK59058.1 - 0.14 10.6 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Glyco_hydro_79C PF16862.5 KIK59062.1 - 5.4e-08 33.7 0.0 1.4e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79C PF16862.5 KIK59064.1 - 6.6e-22 78.3 0.0 6.6e-22 78.3 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Methyltransf_23 PF13489.6 KIK59067.1 - 1.3e-16 60.8 0.0 1.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK59067.1 - 5.3e-15 55.8 0.0 1e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK59067.1 - 8.4e-15 55.3 0.0 2.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK59067.1 - 6e-13 48.9 0.0 9.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK59067.1 - 1.5e-12 48.1 0.0 3.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK59067.1 - 6e-09 35.6 0.1 2.6e-08 33.5 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIK59067.1 - 0.0012 18.5 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 KIK59067.1 - 0.0024 16.5 0.0 0.003 16.2 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 KIK59067.1 - 0.0028 18.7 0.0 0.011 16.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain CheR PF01739.18 KIK59067.1 - 0.053 13.0 0.0 0.2 11.1 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DREV PF05219.12 KIK59067.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase Cerato-platanin PF07249.12 KIK59068.1 - 2.9e-40 137.1 3.7 3.6e-40 136.8 3.7 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 KIK59068.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein Cerato-platanin PF07249.12 KIK59069.1 - 3.6e-40 136.8 4.2 4.5e-40 136.5 4.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 KIK59069.1 - 0.15 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein Cerato-platanin PF07249.12 KIK59070.1 - 4.4e-40 136.5 1.9 5.2e-40 136.3 1.9 1.0 1 0 0 1 1 1 1 Cerato-platanin ABC2_membrane PF01061.24 KIK59071.1 - 8.6e-34 116.8 21.6 8.6e-34 116.8 21.6 2.1 2 1 1 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 KIK59071.1 - 1e-24 87.6 0.0 1.5e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK59071.1 - 0.0014 18.6 0.1 0.0033 17.3 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIK59071.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIK59071.1 - 0.0019 18.1 0.3 0.34 10.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIK59071.1 - 0.0045 17.4 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK59071.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK59071.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KIK59071.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KIK59071.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MAP17 PF15807.5 KIK59071.1 - 0.024 14.9 0.1 0.024 14.9 0.1 1.7 2 0 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 IstB_IS21 PF01695.17 KIK59071.1 - 0.024 14.4 0.0 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KIK59071.1 - 0.029 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK59071.1 - 0.032 14.5 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KIK59071.1 - 0.035 13.8 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KIK59071.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 KIK59071.1 - 0.095 11.8 27.8 0.25 10.4 27.7 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 KIK59071.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK59071.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.4 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KIK59071.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIK59071.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIK59071.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KIK59071.1 - 0.24 11.6 1.1 2.5 8.4 0.1 3.0 3 1 0 3 3 1 0 Putative exonuclease SbcCD, C subunit Retrotran_gag_2 PF14223.6 KIK59073.1 - 6.7e-14 51.7 0.1 6.7e-14 51.7 0.1 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK59073.1 - 0.0016 18.0 2.6 0.0031 17.2 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KIK59073.1 - 0.0051 16.6 0.1 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type ASFV_J13L PF05568.11 KIK59074.1 - 0.2 11.4 0.7 0.35 10.6 0.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein COX17 PF05051.13 KIK59075.1 - 1.6e-20 73.2 4.8 2e-20 72.8 4.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) ATP1G1_PLM_MAT8 PF02038.16 KIK59075.1 - 0.12 11.9 2.3 0.16 11.4 2.3 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family ABC2_membrane PF01061.24 KIK59076.1 - 1.5e-37 129.1 19.1 1.5e-37 129.1 19.1 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 KIK59076.1 - 4.5e-25 88.8 0.0 8.3e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KIK59076.1 - 8.5e-05 21.8 25.5 9.1e-05 21.7 22.8 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KIK59076.1 - 0.0023 17.8 0.3 0.79 9.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIK59076.1 - 0.0032 17.4 0.1 0.0082 16.1 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIK59076.1 - 0.015 15.6 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK59076.1 - 0.036 13.8 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK59076.1 - 0.036 14.5 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KIK59076.1 - 0.044 14.3 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK59076.1 - 0.075 13.3 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK59076.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KIK59076.1 - 0.092 12.5 0.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 KIK59076.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KIK59076.1 - 0.14 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK59076.1 - 0.15 12.5 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK59076.1 - 0.24 11.3 0.0 0.54 10.2 0.0 1.5 1 0 0 1 1 1 0 NTPase ADH_zinc_N PF00107.26 KIK59077.1 - 4.1e-12 46.2 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK59077.1 - 1.2e-06 28.4 0.0 4.6e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK59079.1 - 2e-12 47.2 0.1 3.4e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK59079.1 - 6.7e-07 29.2 0.0 2.9e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DEAD PF00270.29 KIK59083.1 - 6.6e-05 22.7 0.0 8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ADH_N PF08240.12 KIK59084.1 - 8e-07 28.9 0.0 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK59084.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WD40 PF00400.32 KIK59086.1 - 1.1e-116 377.4 74.5 3.1e-10 40.5 0.4 14.0 14 0 0 14 14 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59086.1 - 6.1e-46 154.7 0.2 0.013 15.8 0.0 13.1 2 2 10 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59086.1 - 1e-21 77.3 15.9 0.47 9.3 0.0 12.9 2 1 5 13 13 13 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59086.1 - 2.6e-12 46.4 26.5 7.9 6.6 0.0 12.4 13 0 0 13 13 13 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59086.1 - 5.6e-09 35.2 13.6 1 7.9 0.1 10.8 8 2 3 12 12 12 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK59086.1 - 2.6e-08 33.6 0.4 10 5.4 0.0 7.6 6 3 2 8 8 8 0 WD40-like domain NACHT PF05729.12 KIK59086.1 - 3.1e-07 30.5 0.1 1e-06 28.8 0.1 1.7 1 1 0 1 1 1 1 NACHT domain PQQ PF01011.21 KIK59086.1 - 3.2e-06 26.8 13.3 23 5.1 0.1 10.9 13 0 0 13 13 12 0 PQQ enzyme repeat DPPIV_N PF00930.21 KIK59086.1 - 5.4e-05 22.1 0.1 0.61 8.8 0.0 5.1 3 1 3 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_16 PF13191.6 KIK59086.1 - 0.00052 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain WD40_3 PF15911.5 KIK59086.1 - 0.00076 19.4 7.4 32 4.6 0.0 8.1 8 0 0 8 8 8 0 WD domain, G-beta repeat Peptidase_S9_N PF02897.15 KIK59086.1 - 0.0012 17.7 2.0 15 4.2 0.0 5.7 2 2 3 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain potato_inhibit PF00280.18 KIK59086.1 - 0.0019 18.8 3.2 9.8 6.9 0.1 6.6 8 0 0 8 8 7 0 Potato inhibitor I family Parvo_NS1 PF01057.17 KIK59086.1 - 0.017 14.2 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cuticle_4 PF15955.5 KIK59086.1 - 0.042 14.6 0.3 1.9e+02 2.8 0.0 5.2 6 0 0 6 6 5 0 Cuticle protein NB-ARC PF00931.22 KIK59086.1 - 0.051 12.8 0.2 0.16 11.1 0.0 1.9 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 KIK59086.1 - 0.066 13.6 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK59086.1 - 0.087 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 KIK59086.1 - 0.18 12.0 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain PQQ_2 PF13360.6 KIK59086.1 - 1.7 8.1 27.0 7.4 6.1 9.0 4.9 1 1 2 3 3 3 0 PQQ-like domain F-box PF00646.33 KIK59089.1 - 1.7e-05 24.5 1.3 3.3e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK59089.1 - 0.0002 21.2 0.1 0.00077 19.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like Mt_ATP-synt_B PF05405.14 KIK59089.1 - 0.31 10.6 1.8 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cerato-platanin PF07249.12 KIK59090.1 - 5.4e-38 129.7 2.9 1.6e-37 128.3 2.9 1.6 1 1 0 1 1 1 1 Cerato-platanin Pkinase PF00069.25 KIK59091.1 - 3.9e-10 39.5 0.7 3.5e-06 26.6 0.2 2.9 2 2 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KIK59091.1 - 0.00028 19.8 0.1 0.00049 19.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KIK59091.1 - 0.025 13.9 0.1 0.094 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein tyrosine kinase APH PF01636.23 KIK59091.1 - 0.14 12.1 3.8 12 5.8 0.0 3.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 KIK59092.1 - 4e-13 49.0 0.1 6.3e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK59092.1 - 2e-08 34.2 12.8 3.3e-08 33.5 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KIK59092.1 - 0.11 13.1 0.4 0.46 11.2 0.3 2.1 2 0 0 2 2 2 0 SlyX Casc1_N PF15927.5 KIK59093.1 - 8.3 6.0 15.5 12 5.5 15.5 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Calcipressin PF04847.12 KIK59094.1 - 2e-29 102.7 0.1 2e-29 102.7 0.1 2.3 2 1 0 2 2 2 1 Calcipressin Ccdc124 PF06244.12 KIK59095.1 - 2.3e-28 99.3 20.7 2.3e-28 99.3 20.7 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Aa_trans PF01490.18 KIK59098.1 - 5.3e-28 97.9 21.6 8.5e-28 97.2 21.6 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 KIK59099.1 - 1.6e-18 67.1 0.0 1.8e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59099.1 - 5.9e-06 25.7 0.0 7.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2388 PF09498.10 KIK59100.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF789 PF05623.12 KIK59104.1 - 7.1 6.2 8.7 9.3 5.8 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DNA_pol_phi PF04931.13 KIK59104.1 - 8 4.4 4.9 10 4.1 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi IIGP PF05049.13 KIK59105.1 - 5.4e-23 81.7 0.4 1e-21 77.5 0.0 2.2 1 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK59105.1 - 3.9e-07 30.2 0.0 1.3e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK59105.1 - 0.00062 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK59105.1 - 0.00064 19.7 0.2 0.01 15.8 0.1 2.6 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 KIK59105.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK59105.1 - 0.017 14.9 0.5 0.031 14.0 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIK59105.1 - 0.021 14.2 0.0 0.062 12.6 0.0 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.6 KIK59105.1 - 0.028 14.2 0.1 0.06 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GBP PF02263.19 KIK59105.1 - 0.052 12.8 0.3 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Herpes_Helicase PF02689.14 KIK59105.1 - 0.064 11.2 0.2 0.25 9.2 0.0 1.9 2 0 0 2 2 2 0 Helicase AAA_22 PF13401.6 KIK59105.1 - 0.14 12.5 5.2 2.1 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KIK59105.1 - 0.33 11.0 0.2 0.33 11.0 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_16 PF13191.6 KIK59105.1 - 0.44 10.9 0.1 0.44 10.9 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 KIK59105.1 - 0.49 9.8 3.9 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.17 KIK59105.1 - 0.61 9.8 5.8 1.7 8.4 0.2 2.5 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein CAC1F_C PF16885.5 KIK59105.1 - 1.4 8.6 7.2 0.35 10.5 0.8 2.1 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term ABC_tran PF00005.27 KIK59105.1 - 1.4 9.5 10.2 0.43 11.1 4.2 2.9 2 1 0 2 2 2 0 ABC transporter Mt_ATP-synt_B PF05405.14 KIK59105.1 - 3.9 7.1 15.6 1.5 8.4 1.7 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3632 PF12311.8 KIK59106.1 - 4.8e-34 118.3 0.2 5.9e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans PF04082.18 KIK59107.1 - 2.7e-22 79.1 0.0 3.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF679 PF05078.12 KIK59107.1 - 0.16 11.9 0.1 0.47 10.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF679) COG2 PF06148.11 KIK59109.1 - 0.095 12.8 0.1 0.14 12.3 0.1 1.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 WD40 PF00400.32 KIK59110.1 - 3.9e-13 49.6 2.8 2.2e-09 37.8 0.2 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.12 KIK59110.1 - 1e-07 32.0 0.2 3e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 KIK59110.1 - 0.00052 20.3 0.3 0.26 11.6 0.0 3.2 2 1 1 3 3 2 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KIK59110.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK59110.1 - 0.0019 18.2 0.0 0.0079 16.1 0.0 2.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK59110.1 - 0.0032 17.9 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PsaL PF02605.15 KIK59110.1 - 0.012 15.3 0.1 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI NB-ARC PF00931.22 KIK59110.1 - 0.015 14.5 0.0 0.038 13.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KIK59110.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIK59110.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK59110.1 - 0.024 15.0 0.2 4 7.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK59110.1 - 0.034 14.0 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KIK59110.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 KIK59110.1 - 0.046 14.1 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KIK59110.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 KIK59110.1 - 0.058 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TFIIE_alpha PF02002.17 KIK59110.1 - 0.079 12.8 2.7 0.32 10.9 0.0 2.8 3 0 0 3 3 2 0 TFIIE alpha subunit Tim29 PF10171.9 KIK59110.1 - 0.087 12.3 0.1 0.45 10.0 0.0 2.2 1 1 2 3 3 3 0 Translocase of the Inner Mitochondrial membrane 29 AAA_33 PF13671.6 KIK59110.1 - 0.09 12.9 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain PheRS_DBD1 PF18552.1 KIK59110.1 - 0.11 12.3 0.2 0.33 10.8 0.2 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 1 DUF1678 PF07913.11 KIK59110.1 - 0.11 12.2 0.2 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) RsgA_GTPase PF03193.16 KIK59110.1 - 0.13 12.2 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KIK59110.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 KIK59114.1 - 0.039 14.0 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NACHT PF05729.12 KIK59115.1 - 1.1e-05 25.4 0.1 1.4e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK59115.1 - 1.7e-05 25.3 0.0 2.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK59115.1 - 8.1e-05 22.6 0.0 9.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK59115.1 - 0.00028 21.2 0.0 0.00039 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK59115.1 - 0.00058 19.1 0.0 0.00063 19.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Cytidylate_kin PF02224.18 KIK59115.1 - 0.00098 18.9 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase APS_kinase PF01583.20 KIK59115.1 - 0.0015 18.5 0.5 0.0059 16.5 0.1 2.0 2 1 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 KIK59115.1 - 0.0019 18.6 0.1 0.0034 17.8 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK59115.1 - 0.0029 18.1 0.0 0.0037 17.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 KIK59115.1 - 0.0047 17.3 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KIK59115.1 - 0.0063 16.0 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KIK59115.1 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.3 1 1 0 1 1 1 1 NTPase AAA_30 PF13604.6 KIK59115.1 - 0.012 15.3 0.1 0.013 15.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK59115.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 KIK59115.1 - 0.013 16.1 0.5 0.019 15.5 0.5 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK59115.1 - 0.041 13.0 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KIK59115.1 - 0.045 13.7 0.0 0.084 12.9 0.0 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIK59115.1 - 0.047 13.8 0.4 0.067 13.4 0.3 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIK59115.1 - 0.067 13.1 0.0 0.099 12.5 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 KIK59115.1 - 0.1 13.0 0.1 0.25 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK59115.1 - 0.13 11.3 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIK59115.1 - 0.13 11.8 0.5 0.29 10.7 0.5 1.8 1 1 0 1 1 1 0 AAA domain ADK PF00406.22 KIK59115.1 - 0.18 11.9 0.1 0.4 10.8 0.1 1.6 1 1 0 1 1 1 0 Adenylate kinase CbiA PF01656.23 KIK59115.1 - 0.25 11.4 0.5 0.48 10.5 0.2 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 KIK59116.1 - 4.8e-39 131.7 15.6 1.3e-10 41.6 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59116.1 - 9.8e-15 54.6 0.5 0.0015 18.8 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK59116.1 - 7.2e-07 29.0 0.2 0.39 10.7 0.0 3.9 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK59116.1 - 9.5e-05 21.9 0.0 0.33 10.3 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 KIK59116.1 - 0.00023 20.0 0.0 7.5 5.1 0.0 3.9 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK59116.1 - 0.0019 17.3 0.0 2.8 6.8 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CHAP PF05257.16 KIK59116.1 - 0.0032 18.0 3.3 2 9.0 0.1 3.8 1 1 3 4 4 4 1 CHAP domain PQQ_3 PF13570.6 KIK59116.1 - 0.011 16.2 1.3 10 6.8 0.1 3.8 2 2 2 4 4 4 0 PQQ-like domain NQRA_SLBB PF11973.8 KIK59116.1 - 0.088 13.4 1.3 7.8 7.2 0.0 4.2 2 2 2 4 4 4 0 NQRA C-terminal domain Ret2_MD PF18528.1 KIK59116.1 - 0.17 12.3 0.0 17 5.9 0.0 2.7 2 1 1 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain NACHT PF05729.12 KIK59121.1 - 1.6e-06 28.2 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK59121.1 - 0.00029 20.8 0.0 0.00043 20.3 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIK59121.1 - 0.00077 19.9 0.0 0.0011 19.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KIK59121.1 - 0.0012 18.6 0.1 0.0022 17.8 0.0 1.4 2 0 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 KIK59121.1 - 0.0017 18.8 0.2 0.0037 17.7 0.2 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK59121.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK59121.1 - 0.0025 17.0 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KIK59121.1 - 0.0035 17.1 0.0 0.0051 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK59121.1 - 0.0043 16.3 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.27 KIK59121.1 - 0.0053 17.3 0.0 0.0074 16.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 KIK59121.1 - 0.0064 16.4 0.2 0.023 14.6 0.1 1.9 2 1 0 2 2 2 1 Adenylylsulphate kinase DUF815 PF05673.13 KIK59121.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK59121.1 - 0.015 15.7 0.1 0.039 14.3 0.0 1.7 2 1 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 KIK59121.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 KIK59121.1 - 0.028 14.6 0.2 0.062 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK59121.1 - 0.032 13.5 1.2 0.075 12.3 0.9 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 KIK59121.1 - 0.035 14.1 0.1 1.4 8.9 0.0 2.5 1 1 2 3 3 3 0 AAA domain AAA_7 PF12775.7 KIK59121.1 - 0.051 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIK59121.1 - 0.055 14.0 0.0 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIK59121.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.9 1 1 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 KIK59121.1 - 0.086 12.6 0.5 0.15 11.8 0.3 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 KIK59121.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase TsaE PF02367.17 KIK59121.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KIK59121.1 - 0.13 12.7 0.1 0.28 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK59121.1 - 0.16 12.3 0.1 0.3 11.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK59122.1 - 2.5e-75 246.5 23.1 3.4e-10 40.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59122.1 - 8.8e-33 112.5 1.6 0.0019 18.5 0.0 7.0 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK59122.1 - 4.9e-23 80.5 3.4 0.18 11.8 0.0 7.4 7 0 0 7 7 7 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK59122.1 - 4.2e-12 45.7 0.0 1 8.2 0.0 6.8 3 2 2 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK59122.1 - 3e-11 43.6 2.3 0.061 13.1 0.1 6.5 1 1 4 5 5 5 4 Lipoprotein LpqB beta-propeller domain Ret2_MD PF18528.1 KIK59122.1 - 1.3e-09 38.3 0.0 3.3 8.2 0.0 6.4 1 1 5 6 6 6 2 RNA editing 3' terminal uridylyl transferase 2 middle domain Proteasome_A_N PF10584.9 KIK59122.1 - 2.1e-07 30.5 8.0 37 4.1 0.0 7.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature CHAP PF05257.16 KIK59122.1 - 7.6e-07 29.6 11.2 1 10.0 0.1 6.1 1 1 5 6 6 6 2 CHAP domain WD40_like PF17005.5 KIK59122.1 - 1e-06 28.3 0.0 0.18 11.1 0.0 5.2 4 1 2 6 6 6 1 WD40-like domain Nup160 PF11715.8 KIK59122.1 - 1.3e-06 27.4 0.1 8.3 4.9 0.0 5.8 6 1 1 7 7 7 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK59122.1 - 0.00018 21.9 3.2 8.7 7.0 0.1 5.1 4 1 2 6 6 6 1 PQQ-like domain DPPIV_N PF00930.21 KIK59122.1 - 0.006 15.4 0.0 12 4.5 0.0 5.1 4 2 1 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Frtz PF11768.8 KIK59122.1 - 0.0086 14.4 0.0 40 2.3 0.0 4.7 4 3 2 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5018 PF16410.5 KIK59122.1 - 0.019 13.7 0.0 3.2 6.4 0.0 3.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5018) 5-FTHF_cyc-lig PF01812.20 KIK59122.1 - 0.072 12.9 0.0 80 3.0 0.0 4.9 7 0 0 7 7 7 0 5-formyltetrahydrofolate cyclo-ligase family Cuticle_4 PF15955.5 KIK59122.1 - 0.083 13.6 3.0 3.5e+02 2.0 0.1 5.5 7 0 0 7 7 6 0 Cuticle protein Caroten_synth PF04240.12 KIK59122.1 - 0.2 11.5 0.2 72 3.1 0.0 3.4 4 0 0 4 4 4 0 Carotenoid biosynthesis protein KASH_CCD PF14662.6 KIK59123.1 - 2.1 8.1 12.6 4.9 6.9 12.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DDE_1 PF03184.19 KIK59124.1 - 7.7e-05 22.4 0.0 8.3e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RVT PF13966.6 KIK59125.1 - 0.00077 20.1 3.4 0.00077 20.1 3.4 2.4 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK59126.1 - 8.8e-06 25.4 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_35 PF14516.6 KIK59126.1 - 0.0043 15.9 0.1 0.18 10.6 0.0 2.0 2 0 0 2 2 2 2 AAA-like domain DUF4191 PF13829.6 KIK59127.1 - 0.028 13.8 0.4 0.17 11.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Ald_deCOase PF11266.8 KIK59130.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase Synapsin_N PF10581.9 KIK59130.1 - 0.54 10.2 2.0 0.77 9.8 0.0 2.3 3 0 0 3 3 3 0 Synapsin N-terminal Pet191_N PF10203.9 KIK59130.1 - 0.84 10.0 5.1 1.2 9.5 0.2 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF3435 PF11917.8 KIK59132.1 - 0.059 12.3 0.0 0.19 10.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3435) Phage_holin_2_3 PF16080.5 KIK59133.1 - 0.17 11.7 3.0 0.35 10.6 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 EMP70 PF02990.16 KIK59133.1 - 0.17 10.5 9.9 0.24 10.0 9.9 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Pribosyltran_N PF13793.6 KIK59134.1 - 6.3e-49 164.8 0.4 3.6e-48 162.3 0.1 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIK59134.1 - 5.8e-33 114.5 1.9 4.3e-16 59.5 0.0 3.3 2 1 1 3 3 3 3 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIK59134.1 - 2.9e-18 65.9 0.4 1.8e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 KIK59134.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_kinase PF00696.28 KIK59135.1 - 3.9e-43 147.8 4.6 1.9e-42 145.5 2.3 2.0 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 KIK59135.1 - 1.6e-07 31.2 0.3 0.00029 20.7 0.1 2.8 3 0 0 3 3 3 2 PUA domain Moricin PF06451.11 KIK59135.1 - 0.19 11.5 1.8 0.46 10.3 0.1 2.5 3 0 0 3 3 3 0 Moricin F-box PF00646.33 KIK59136.1 - 1e-05 25.3 0.0 3.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK59136.1 - 3.3e-05 23.7 0.0 0.00023 21.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like EnY2 PF10163.9 KIK59136.1 - 0.016 15.5 2.5 0.037 14.4 1.9 2.0 1 1 0 1 1 1 0 Transcription factor e(y)2 F-box_4 PF15966.5 KIK59136.1 - 0.062 13.2 0.2 1 9.3 0.0 2.7 2 0 0 2 2 2 0 F-box zf-C2HE PF16278.5 KIK59136.1 - 1.7 9.1 7.1 0.36 11.3 0.4 3.4 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger F-box PF00646.33 KIK59137.1 - 1.6e-05 24.7 0.0 6.3e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK59137.1 - 0.00047 20.0 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK59137.1 - 0.018 14.9 0.4 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 F-box ALP_N PF17989.1 KIK59137.1 - 0.21 11.8 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 Actin like proteins N terminal domain F-box-like PF12937.7 KIK59138.1 - 5.3e-06 26.2 0.0 3.8e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK59138.1 - 1.1e-05 25.2 0.1 3.4e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain Snapin_Pallidin PF14712.6 KIK59138.1 - 0.1 13.0 0.2 0.31 11.5 0.2 1.8 1 0 0 1 1 1 0 Snapin/Pallidin F-box_4 PF15966.5 KIK59138.1 - 0.11 12.4 4.8 0.47 10.3 0.0 3.1 3 0 0 3 3 3 0 F-box F-box-like PF12937.7 KIK59139.1 - 6.3e-06 26.0 0.3 6.5e-05 22.7 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK59139.1 - 1.1e-05 25.1 0.0 3.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain zf-PARP PF00645.18 KIK59139.1 - 0.042 14.7 4.1 0.13 13.1 0.0 3.2 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Speriolin_C PF15059.6 KIK59139.1 - 0.068 13.3 0.4 3.1 7.9 0.1 2.4 1 1 1 2 2 2 0 Speriolin C-terminus zf-C2HE PF16278.5 KIK59140.1 - 0.01 16.3 2.7 0.18 12.3 0.9 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CDC45 PF02724.14 KIK59141.1 - 0.71 8.1 3.8 0.76 8.0 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DOPA_dioxygen PF08883.11 KIK59142.1 - 1.9e-32 111.6 0.0 2.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Flp_N PF03930.14 KIK59142.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus F-box-like PF12937.7 KIK59143.1 - 2.5e-07 30.5 0.1 2.5e-07 30.5 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK59143.1 - 0.054 13.4 0.2 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK59144.1 - 4.7e-07 29.6 0.1 1.4e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK59144.1 - 0.029 14.3 0.1 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KIK59144.1 - 0.076 13.0 0.2 0.11 12.5 0.2 1.5 1 1 0 1 1 1 0 F-box-like domain ADH_zinc_N PF00107.26 KIK59145.1 - 1.3e-10 41.4 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK59145.1 - 1.4e-07 31.4 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK59145.1 - 0.00041 21.4 0.0 0.00073 20.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RTBV_P12 PF06361.11 KIK59145.1 - 0.019 15.4 0.0 0.074 13.5 0.0 1.9 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein ADH_zinc_N PF00107.26 KIK59146.1 - 2e-10 40.7 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK59146.1 - 1.1e-08 34.8 0.0 3.3e-08 33.4 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK59146.1 - 0.033 15.2 0.0 0.059 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase_fungal PF17667.1 KIK59148.1 - 6.1e-30 104.3 0.1 7e-24 84.4 0.1 2.2 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK59148.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59148.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK59149.1 - 6.8e-26 91.0 0.1 9.8e-24 83.9 0.2 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK59149.1 - 4.7e-05 22.9 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK59150.1 - 1.8e-24 86.3 0.0 3.1e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK59150.1 - 0.00042 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK59150.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 KIK59151.1 - 7.7e-21 74.7 0.0 5.1e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Cerato-platanin PF07249.12 KIK59152.1 - 3.7e-27 94.8 0.4 4.5e-27 94.5 0.4 1.1 1 0 0 1 1 1 1 Cerato-platanin Baculo_E66 PF04850.12 KIK59152.1 - 0.011 14.5 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein Cerato-platanin PF07249.12 KIK59153.1 - 7.8e-37 126.0 3.1 9.1e-37 125.8 3.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KIK59153.1 - 0.0053 16.6 1.4 0.0085 15.9 1.4 1.4 1 1 0 1 1 1 1 Barwin family DDE_1 PF03184.19 KIK59155.1 - 8e-19 68.0 0.0 1.3e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK59155.1 - 0.046 13.5 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease RHSP PF07999.11 KIK59156.1 - 0.017 14.0 0.4 0.92 8.2 0.4 2.1 1 1 0 1 1 1 0 Retrotransposon hot spot protein AAA_16 PF13191.6 KIK59156.1 - 0.073 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TetR_C_13 PF16925.5 KIK59156.1 - 0.16 11.9 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain p450 PF00067.22 KIK59158.1 - 3.6e-52 177.7 0.0 4.7e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MatE PF01554.18 KIK59159.1 - 1.6e-43 148.1 32.8 1e-24 87.0 7.3 3.7 4 0 0 4 4 4 3 MatE Polysacc_synt_C PF14667.6 KIK59159.1 - 1.3e-05 25.2 0.7 1.3e-05 25.2 0.7 3.7 4 1 0 5 5 5 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 KIK59159.1 - 1.9e-05 23.5 0.7 1.9e-05 23.5 0.7 2.4 2 0 0 2 2 2 1 Lipid II flippase MurJ zinc_ribbon_6 PF14599.6 KIK59160.1 - 0.02 14.9 0.4 0.042 13.9 0.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon DUF4711 PF15829.5 KIK59160.1 - 0.038 13.9 0.4 0.099 12.6 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4711) F-box PF00646.33 KIK59162.1 - 0.0001 22.0 0.5 0.00067 19.5 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK59162.1 - 0.00098 19.0 0.1 0.0064 16.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like Speriolin_C PF15059.6 KIK59162.1 - 0.0014 18.7 0.2 0.7 10.0 0.1 2.6 2 0 0 2 2 2 2 Speriolin C-terminus F-box-like PF12937.7 KIK59163.1 - 1.1e-07 31.6 0.1 8.9e-07 28.7 0.0 2.7 2 1 0 2 2 2 1 F-box-like F-box_5 PF18511.1 KIK59163.1 - 0.11 12.0 0.1 0.33 10.5 0.1 1.8 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KIK59164.1 - 0.013 15.4 0.3 0.83 9.6 0.0 2.8 2 0 0 2 2 2 0 F-box-like NO_synthase PF02898.15 KIK59164.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain Abhydrolase_1 PF00561.20 KIK59164.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.7 KIK59165.1 - 0.013 15.4 3.2 0.043 13.7 0.3 2.7 3 0 0 3 3 3 0 F-box-like Cyt-b5 PF00173.28 KIK59166.1 - 3.8e-21 75.0 0.6 8.5e-21 73.9 0.3 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KIK59166.1 - 1.1e-12 48.5 14.2 1.1e-12 48.5 14.2 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily p450 PF00067.22 KIK59167.1 - 1.3e-67 228.6 0.0 1.6e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK59169.1 - 6.7e-69 232.8 0.0 9.1e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK59170.1 - 3.6e-69 233.7 0.0 4.7e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK59171.1 - 9.6e-91 304.8 0.0 2.5e-59 201.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 YcgR_2 PF12945.7 KIK59171.1 - 0.014 15.5 0.0 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR DUF1965 PF09248.10 KIK59171.1 - 0.058 13.2 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) DUF4381 PF14316.6 KIK59172.1 - 0.082 13.1 0.1 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DctP PF03480.13 KIK59173.1 - 0.051 12.9 0.0 5.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Pkinase PF00069.25 KIK59174.1 - 9.2e-16 58.0 0.0 9.7e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59174.1 - 1.6e-05 24.3 0.0 1.7e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK59174.1 - 0.021 14.7 0.6 0.027 14.4 0.6 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK59174.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIN_8 PF18476.1 KIK59175.1 - 0.036 13.9 1.0 0.06 13.2 1.0 1.3 1 0 0 1 1 1 0 PIN like domain WD40 PF00400.32 KIK59176.1 - 5.8e-70 229.5 58.8 3.6e-10 40.3 1.4 10.3 11 0 0 11 11 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59176.1 - 8e-31 106.2 0.4 0.0031 17.8 0.0 8.5 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59176.1 - 4.4e-15 55.5 4.7 1 8.3 0.0 7.6 2 2 4 7 7 7 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59176.1 - 1.3e-09 37.7 10.9 6.8 6.8 0.0 7.9 8 0 0 8 8 8 4 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59176.1 - 8.1e-07 28.1 6.7 10 4.6 0.0 7.7 8 0 0 8 8 8 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK59176.1 - 9.4e-07 28.4 0.0 8.5 5.6 0.0 6.1 3 3 4 7 7 7 1 WD40-like domain NACHT PF05729.12 KIK59176.1 - 8.9e-06 25.7 0.3 6e-05 23.0 0.3 2.1 1 1 0 1 1 1 1 NACHT domain PQQ PF01011.21 KIK59176.1 - 3.7e-05 23.4 2.4 50 4.1 0.1 7.4 8 0 0 8 8 8 0 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK59176.1 - 0.0014 19.3 0.7 1.8e+02 2.9 0.0 5.8 7 0 0 7 7 5 0 Cuticle protein WD40_3 PF15911.5 KIK59176.1 - 0.0095 15.9 4.7 1e+02 3.0 0.0 6.7 8 0 0 8 8 7 0 WD domain, G-beta repeat AAA_16 PF13191.6 KIK59176.1 - 0.05 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK59176.1 - 0.07 12.3 0.4 0.37 9.9 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain PQQ_2 PF13360.6 KIK59176.1 - 0.075 12.6 15.9 3.3 7.2 1.1 4.5 1 1 2 4 4 4 0 PQQ-like domain DUF1843 PF08898.10 KIK59176.1 - 0.088 13.3 0.0 0.83 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Retrotran_gag_2 PF14223.6 KIK59177.1 - 1.4e-12 47.4 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AcetDehyd-dimer PF09290.11 KIK59177.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Abhydrolase_1 PF00561.20 KIK59179.1 - 6.9e-24 84.9 0.0 5.4e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK59179.1 - 6.3e-16 58.4 0.0 9.4e-14 51.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK59179.1 - 7e-14 52.9 0.3 1.5e-13 51.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KIK59179.1 - 5.7e-06 26.1 0.0 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KIK59179.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 KIK59179.1 - 0.0025 17.5 0.1 0.0046 16.6 0.1 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KIK59179.1 - 0.012 15.5 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Ndr PF03096.14 KIK59179.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.11 KIK59179.1 - 0.03 13.7 0.0 0.36 10.1 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pectate_lyase PF03211.13 KIK59180.1 - 5e-83 277.6 5.1 5.8e-83 277.4 5.1 1.0 1 0 0 1 1 1 1 Pectate lyase zf-C3HC4_3 PF13920.6 KIK59181.1 - 1.1e-08 34.8 5.5 1.6e-08 34.3 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK59181.1 - 2.8e-07 30.4 10.5 4.5e-07 29.7 10.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK59181.1 - 1.5e-05 24.8 11.2 2.4e-05 24.1 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK59181.1 - 2.2e-05 24.7 10.9 3.4e-05 24.1 10.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK59181.1 - 0.00062 19.6 8.4 0.0012 18.7 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK59181.1 - 0.0033 17.2 10.5 0.0066 16.3 10.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIK59181.1 - 0.025 14.4 7.0 0.05 13.4 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 KIK59181.1 - 0.026 14.5 6.4 0.11 12.5 6.4 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-RING_UBOX PF13445.6 KIK59181.1 - 0.051 13.6 10.5 0.1 12.6 10.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 KIK59181.1 - 0.12 12.4 6.4 0.32 11.0 6.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-CHY PF05495.12 KIK59181.1 - 0.13 12.7 3.8 0.29 11.7 3.8 1.5 1 0 0 1 1 1 0 CHY zinc finger SCO1-SenC PF02630.14 KIK59181.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Baculo_IE-1 PF05290.11 KIK59181.1 - 0.3 11.0 2.5 0.84 9.6 2.5 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 KIK59181.1 - 0.5 10.6 7.6 1.2 9.3 7.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CENP-K PF11802.8 KIK59181.1 - 1.1 8.7 18.2 0.61 9.6 15.5 1.6 1 1 1 2 2 2 0 Centromere-associated protein K DUF3811 PF11656.8 KIK59181.1 - 1.5 9.2 14.3 2.3e+02 2.2 14.3 2.5 1 1 0 1 1 1 0 YjbD family (DUF3811) APG6_N PF17675.1 KIK59181.1 - 2.6 8.6 24.1 6.8 7.2 24.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 KIK59181.1 - 4.5 8.0 10.1 13 6.5 10.0 1.9 1 1 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 KIK59181.1 - 5.2 4.8 6.3 6.9 4.5 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 KIK59181.1 - 6.9 6.9 23.3 0.12 12.6 12.8 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Pro_CA PF00484.19 KIK59181.1 - 9.3 6.5 8.9 1.3 9.3 0.0 2.5 2 1 0 2 2 2 0 Carbonic anhydrase zf-C3HC4_3 PF13920.6 KIK59182.1 - 4.5e-10 39.2 6.4 6.4e-10 38.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK59182.1 - 1.6e-08 34.3 10.3 2.7e-08 33.6 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK59182.1 - 2.6e-07 30.4 10.6 4.1e-07 29.7 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK59182.1 - 5.8e-07 29.7 10.3 9.4e-07 29.1 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK59182.1 - 6.9e-05 22.6 9.7 0.00012 21.9 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK59182.1 - 0.00022 21.0 10.2 0.00037 20.3 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIK59182.1 - 0.0017 18.1 7.2 0.0036 17.1 7.2 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KIK59182.1 - 0.0045 17.0 11.7 0.0082 16.1 11.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-CHY PF05495.12 KIK59182.1 - 0.024 15.1 6.4 0.039 14.5 6.4 1.3 1 0 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.12 KIK59182.1 - 0.06 13.3 10.0 0.11 12.5 8.2 2.0 1 1 1 2 2 2 0 zinc-ribbons zf-RING_11 PF17123.5 KIK59182.1 - 0.11 12.3 5.1 0.07 12.9 2.8 1.9 1 1 1 2 2 2 0 RING-like zinc finger BST2 PF16716.5 KIK59182.1 - 0.11 13.1 0.3 0.17 12.5 0.3 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF448 PF04296.13 KIK59182.1 - 0.15 11.9 1.2 1 9.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF448) zf-rbx1 PF12678.7 KIK59182.1 - 0.94 9.8 9.9 1.8 8.9 9.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KIK59182.1 - 1.2 9.4 9.7 2.8 8.2 9.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf_UBZ PF18439.1 KIK59182.1 - 1.4 8.6 6.2 2.2 8.0 0.0 3.1 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KIK59182.1 - 1.5 8.9 11.7 9.2 6.4 11.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KIK59182.1 - 3.1 7.8 7.4 50 4.0 7.4 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 KIK59182.1 - 3.2 7.8 9.6 1.5 8.9 2.2 2.4 1 1 1 2 2 2 0 Transposase zinc-binding domain ATG16 PF08614.11 KIK59183.1 - 0.00066 20.0 14.4 0.0008 19.7 14.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KIK59183.1 - 0.0086 16.5 2.2 0.022 15.2 2.2 1.8 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 KIK59183.1 - 0.018 14.4 11.1 0.022 14.1 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MCM3AP_GANP PF16769.5 KIK59183.1 - 0.018 13.3 4.0 0.021 13.1 4.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Laminin_II PF06009.12 KIK59183.1 - 0.024 14.7 2.8 0.024 14.7 2.8 2.0 1 1 1 2 2 2 0 Laminin Domain II HTH_Tnp_ISL3 PF13542.6 KIK59183.1 - 0.047 13.1 0.1 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Tmemb_cc2 PF10267.9 KIK59183.1 - 0.075 12.2 11.3 0.022 13.9 8.2 1.6 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein UPF0242 PF06785.11 KIK59183.1 - 0.11 12.6 8.6 0.14 12.2 8.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 KIK59183.1 - 0.87 9.7 24.7 1 9.4 24.7 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF99 PF01949.16 KIK59183.1 - 0.88 9.0 4.0 0.96 8.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF99 V_ATPase_I PF01496.19 KIK59183.1 - 1 7.2 5.1 1.1 7.1 5.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCRF PF03462.18 KIK59183.1 - 1.1 9.1 9.7 1.3 8.9 9.7 1.2 1 0 0 1 1 1 0 PCRF domain DUF2570 PF10828.8 KIK59183.1 - 1.2 9.0 7.3 1.7 8.5 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1664 PF07889.12 KIK59183.1 - 1.4 9.0 6.7 2.2 8.3 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SpoVR PF04293.13 KIK59183.1 - 2.6 6.6 6.5 3 6.4 6.5 1.0 1 0 0 1 1 1 0 SpoVR like protein TMPIT PF07851.13 KIK59183.1 - 2.6 7.2 6.7 3 7.0 6.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 KIK59183.1 - 3.2 6.2 7.2 3.4 6.1 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 KIK59183.1 - 3.5 8.3 18.8 0.51 11.0 10.7 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KIK59183.1 - 4.5 7.8 20.7 8.7 6.9 20.8 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region CorA PF01544.18 KIK59183.1 - 5.3 6.3 8.5 4.2 6.6 7.6 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF572 PF04502.13 KIK59183.1 - 5.3 6.6 13.4 6.3 6.3 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2205 PF10224.9 KIK59183.1 - 6.1 6.9 13.5 1 9.4 3.4 2.8 1 1 2 3 3 3 0 Short coiled-coil protein zf-RING_5 PF14634.6 KIK59184.1 - 1.5e-08 34.5 10.6 2.5e-08 33.8 10.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIK59184.1 - 1.1e-07 31.6 4.8 1.8e-07 30.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK59184.1 - 1.1e-05 25.2 6.8 1.9e-05 24.4 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK59184.1 - 3.9e-05 23.4 9.1 6.5e-05 22.7 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK59184.1 - 0.00013 22.2 9.0 0.00022 21.5 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK59184.1 - 0.0023 17.7 5.5 0.0052 16.6 5.5 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 EzrA PF06160.12 KIK59184.1 - 0.0078 14.4 10.7 0.023 12.9 10.7 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA zf-RING_UBOX PF13445.6 KIK59184.1 - 0.11 12.5 10.5 0.24 11.5 10.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger SCO1-SenC PF02630.14 KIK59184.1 - 0.13 12.2 1.2 0.21 11.5 0.1 1.9 2 1 0 2 2 2 0 SCO1/SenC zinc-ribbons_6 PF07191.12 KIK59184.1 - 0.15 12.1 6.4 1.5 8.8 6.4 2.2 1 1 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 KIK59184.1 - 0.33 10.8 8.4 0.61 9.9 8.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KIK59184.1 - 1.9 8.6 8.8 29 4.8 9.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 KIK59184.1 - 3.5 7.9 7.3 11 6.2 7.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING NPV_P10 PF05531.12 KIK59184.1 - 3.8 8.1 6.0 0.99 9.9 1.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein betaPIX_CC PF16523.5 KIK59184.1 - 7.5 6.5 13.4 1.8 8.4 7.5 2.4 1 1 1 2 2 2 0 betaPIX coiled coil Pyr_redox_2 PF07992.14 KIK59185.1 - 1.8e-14 53.7 0.0 3e-11 43.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK59185.1 - 4.9e-14 52.2 0.3 3.7e-10 39.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KIK59185.1 - 5.3e-14 51.5 0.0 8.8e-12 44.2 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK59185.1 - 1.7e-13 50.5 0.3 3.8e-11 42.8 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK59185.1 - 3.3e-08 33.6 0.0 1.1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK59185.1 - 5.5e-08 33.3 0.2 0.0066 17.0 0.4 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK59185.1 - 1.2e-05 25.4 0.0 0.41 10.6 0.0 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KIK59185.1 - 1.2e-05 25.1 0.8 0.019 14.6 0.1 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK59185.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK59185.1 - 0.0064 15.8 0.1 0.99 8.7 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KIK59185.1 - 0.024 13.7 0.1 0.054 12.6 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIK59185.1 - 0.048 12.9 0.6 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KIK59185.1 - 0.049 12.7 5.1 2.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KIK59185.1 - 0.06 13.8 0.1 16 6.0 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KIK59185.1 - 0.094 11.4 4.5 0.61 8.7 0.3 2.7 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KIK59185.1 - 0.16 11.0 0.8 1 8.4 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KIK59185.1 - 0.19 11.0 0.7 0.46 9.8 0.7 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KIK59185.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMP_synt_C PF00958.22 KIK59186.1 - 1.8e-45 152.9 0.1 3.7e-45 151.9 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KIK59186.1 - 1.1e-33 116.6 0.0 2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK59186.1 - 7.4e-10 38.9 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KIK59186.1 - 7.5e-10 38.3 0.3 4.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 KIK59186.1 - 0.0022 16.9 0.1 0.0038 16.1 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KIK59186.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KIK59186.1 - 0.0072 15.9 0.0 0.019 14.5 0.0 1.7 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 KIK59186.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.19 KIK59186.1 - 0.037 13.3 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 KIK59186.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family AMP-binding PF00501.28 KIK59187.1 - 3.9e-27 94.9 0.0 1.5e-26 93.0 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK59187.1 - 9e-27 93.8 0.0 1.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK59187.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK59187.1 - 0.012 15.5 0.2 0.085 12.7 0.0 2.3 3 0 0 3 3 3 0 NAD(P)H-binding PP-binding PF00550.25 KIK59187.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Oxidored_FMN PF00724.20 KIK59189.1 - 1.6e-67 228.2 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 KIK59190.1 - 5.1e-23 81.6 17.6 6.4e-19 68.1 7.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_UL49_2 PF04823.12 KIK59190.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein SPC25 PF06703.11 KIK59190.1 - 0.82 9.4 7.9 1.2 8.9 0.0 3.8 3 1 1 4 4 4 0 Microsomal signal peptidase 25 kDa subunit (SPC25) F-box-like PF12937.7 KIK59193.1 - 0.00013 21.7 0.3 0.00047 20.0 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KIK59193.1 - 0.12 12.0 0.2 0.27 10.8 0.2 1.6 1 0 0 1 1 1 0 F-box YoqO PF14037.6 KIK59194.1 - 0.23 12.0 2.8 1.1 9.8 2.0 1.9 1 1 0 1 1 1 0 YoqO-like protein Abhydrolase_1 PF00561.20 KIK59197.1 - 1.1e-13 51.4 0.0 6.9e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK59197.1 - 6.7e-09 35.4 0.0 9.4e-08 31.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK59197.1 - 1.5e-08 35.6 0.0 1.8e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIK59197.1 - 8e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIK59197.1 - 0.01 15.6 0.2 0.12 12.2 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase VbhA PF18495.1 KIK59197.1 - 0.061 13.2 0.8 0.11 12.3 0.8 1.4 1 0 0 1 1 1 0 Antitoxin VbhA DLH PF01738.18 KIK59197.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Med4 PF10018.9 KIK59201.1 - 0.022 14.5 1.3 0.7 9.5 0.2 2.5 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 PIG-P PF08510.12 KIK59201.1 - 0.04 13.8 0.5 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 PIG-P BAR PF03114.18 KIK59201.1 - 0.11 12.2 1.3 0.1 12.3 0.3 1.5 2 0 0 2 2 2 0 BAR domain gag_pre-integrs PF13976.6 KIK59205.1 - 3.1e-08 33.4 0.9 3.1e-08 33.4 0.9 1.7 2 0 0 2 2 2 1 GAG-pre-integrase domain Zn_Tnp_IS91 PF14319.6 KIK59205.1 - 0.048 13.7 0.6 0.067 13.2 0.6 1.3 1 1 0 1 1 1 0 Transposase zinc-binding domain Cellulase PF00150.18 KIK59208.1 - 1.4e-12 47.6 0.0 1.3e-08 34.6 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KIK59208.1 - 3e-06 27.7 0.1 1.6e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KIK59208.1 - 0.026 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Cellulase PF00150.18 KIK59209.1 - 4.6e-44 150.9 0.0 5.8e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK59209.1 - 2.1e-14 53.1 5.7 2.1e-14 53.1 5.7 3.5 4 0 0 4 4 4 1 Fungal cellulose binding domain Peptidase_M24 PF00557.24 KIK59210.1 - 0.053 13.2 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 CxC2 PF18803.1 KIK59211.1 - 5.1e-39 132.7 0.3 7e-39 132.3 0.3 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK59211.1 - 1.7e-07 31.4 0.1 2.6e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK59211.1 - 1.1e-05 25.2 0.0 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases DUF3678 PF12435.8 KIK59213.1 - 2.2 7.7 0.0 2.2 7.7 0.0 5.4 6 1 0 6 6 6 0 Protein of unknown function (DUF3678) TPR_12 PF13424.6 KIK59216.1 - 3.7e-16 59.2 5.7 7.1e-08 32.6 1.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.6 KIK59216.1 - 8.5e-07 28.7 4.6 1.9e-05 24.3 1.0 1.9 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KIK59216.1 - 0.00033 20.6 5.0 12 6.3 0.2 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat KNOX2 PF03791.13 KIK59216.1 - 0.0011 18.4 3.4 12 5.5 0.1 4.2 4 0 0 4 4 4 1 KNOX2 domain V-SNARE_C PF12352.8 KIK59216.1 - 0.0014 18.8 0.0 7.2 7.0 0.0 3.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DNA_pol_A_exoN PF18305.1 KIK59216.1 - 0.003 17.8 0.1 7.5 6.9 0.0 3.7 3 1 1 4 4 4 1 3' to 5' exonuclease C-terminal domain TPR_10 PF13374.6 KIK59216.1 - 0.0047 16.7 6.2 0.86 9.6 0.2 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat OEP PF02321.18 KIK59216.1 - 0.09 12.6 7.0 3.7 7.3 1.7 3.1 1 1 1 2 2 2 0 Outer membrane efflux protein DUF1547 PF07577.11 KIK59216.1 - 0.19 12.2 0.0 20 5.7 0.0 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1547) DUF4398 PF14346.6 KIK59216.1 - 0.94 10.1 11.5 10 6.8 1.5 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_1 PF00515.28 KIK59216.1 - 0.98 9.4 4.3 31 4.6 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Na_trans_cytopl PF11933.8 KIK59219.1 - 0.016 15.1 0.6 0.016 15.1 0.6 1.1 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel BAF1_ABF1 PF04684.13 KIK59221.1 - 0.058 12.5 0.0 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor LAG1-DNAbind PF09271.11 KIK59222.1 - 0.062 13.9 0.0 0.063 13.9 0.0 1.0 1 0 0 1 1 1 0 LAG1, DNA binding CpXC PF14353.6 KIK59226.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 CpXC protein Spem1 PF15670.5 KIK59227.1 - 0.048 13.2 0.8 0.088 12.4 0.8 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Sporozoite_P67 PF05642.11 KIK59227.1 - 0.12 10.4 15.5 0.19 9.8 15.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Na_Ca_ex PF01699.24 KIK59230.1 - 1e-15 58.0 34.9 1.9e-12 47.4 12.8 4.1 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KIK59230.1 - 3.1e-13 50.2 11.8 3.1e-13 50.2 11.8 4.1 4 0 0 4 4 4 1 Inner membrane component domain DUF4149 PF13664.6 KIK59230.1 - 0.045 14.1 0.3 0.045 14.1 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) SLATT_5 PF18160.1 KIK59230.1 - 0.13 11.5 0.2 0.61 9.4 0.2 2.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 p450 PF00067.22 KIK59231.1 - 1.3e-60 205.5 0.0 1.5e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK59232.1 - 5.6e-64 216.6 0.0 6.2e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DivIC PF04977.15 KIK59237.1 - 5.5 6.8 7.0 1.4 8.8 1.4 2.6 2 0 0 2 2 2 0 Septum formation initiator KDZ PF18758.1 KIK59239.1 - 0.00017 21.2 0.7 0.00021 21.0 0.7 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 KIK59240.1 - 9.4e-41 138.7 0.0 1.5e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases DUF1388 PF07142.12 KIK59241.1 - 0.034 14.1 0.9 0.077 13.0 0.9 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Yuri_gagarin PF15934.5 KIK59242.1 - 0.068 13.0 0.7 0.094 12.5 0.7 1.2 1 0 0 1 1 1 0 Yuri gagarin HAUS2 PF15003.6 KIK59243.1 - 0.0031 17.3 2.4 0.0031 17.3 2.4 1.4 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 2 HALZ PF02183.18 KIK59243.1 - 0.012 15.8 8.6 2.3 8.5 0.1 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 KIK59243.1 - 0.014 15.2 4.5 0.014 15.2 4.5 2.0 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KIK59243.1 - 0.06 13.5 6.8 0.42 10.7 0.5 3.2 3 1 0 3 3 3 0 bZIP transcription factor YabA PF06156.13 KIK59243.1 - 0.22 12.1 8.8 5.4 7.7 6.9 2.7 1 1 1 2 2 2 0 Initiation control protein YabA DivIVA PF05103.13 KIK59243.1 - 1 9.4 6.6 13 5.9 0.2 3.0 1 1 2 3 3 3 0 DivIVA protein TolA_bind_tri PF16331.5 KIK59243.1 - 2 8.5 10.4 0.97 9.6 7.4 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation Spc29 PF17082.5 KIK59243.1 - 2.7 7.8 5.2 21 4.8 0.3 2.7 1 1 2 3 3 3 0 Spindle Pole Component 29 UPF0449 PF15136.6 KIK59243.1 - 4.5 7.8 6.0 4 8.0 2.6 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 p450 PF00067.22 KIK59244.1 - 2.9e-65 220.8 0.0 3.9e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK59245.1 - 9.5e-69 232.3 0.0 1.2e-68 232.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Retrotran_gag_2 PF14223.6 KIK59246.1 - 6e-11 42.2 0.0 8.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DEC-1_N PF04625.13 KIK59246.1 - 0.021 13.9 2.4 0.024 13.7 2.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Prok-TraM PF09228.10 KIK59246.1 - 0.028 14.8 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM p450 PF00067.22 KIK59247.1 - 1.3e-05 24.1 0.0 1.5e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK59249.1 - 2.6e-66 224.3 0.0 3.1e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPRTase PF14681.6 KIK59250.1 - 3.9e-41 140.8 0.4 4.1e-40 137.4 0.1 2.2 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.7 KIK59250.1 - 1.3e-21 77.8 0.1 5.1e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KIK59250.1 - 1.8e-20 73.8 0.0 9.4e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK59250.1 - 1.1e-06 28.9 0.1 7.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Hydrolase PF00702.26 KIK59250.1 - 2.2e-06 28.1 0.2 5.7e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 KIK59250.1 - 3.1e-06 26.8 0.3 9e-06 25.3 0.3 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain KAP_NTPase PF07693.14 KIK59250.1 - 5.7e-06 25.8 0.0 3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 KAP family P-loop domain AAA_18 PF13238.6 KIK59250.1 - 0.00016 22.2 0.0 0.00075 20.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK59250.1 - 0.00034 21.0 0.0 0.0022 18.4 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain PRTase_2 PF15609.6 KIK59250.1 - 0.00066 19.2 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase Zeta_toxin PF06414.12 KIK59250.1 - 0.0014 17.9 0.1 0.0098 15.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Put_Phosphatase PF06888.12 KIK59250.1 - 0.002 17.5 0.1 0.0048 16.3 0.0 1.6 2 0 0 2 2 2 1 Putative Phosphatase KTI12 PF08433.10 KIK59250.1 - 0.006 16.1 0.0 0.073 12.5 0.0 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 KIK59250.1 - 0.0067 16.2 0.0 0.58 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIK59250.1 - 0.013 15.9 0.0 0.15 12.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIK59250.1 - 0.03 13.5 0.0 2.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KIK59250.1 - 0.04 13.1 0.0 0.098 11.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KIK59250.1 - 0.04 13.8 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KIK59250.1 - 0.042 13.9 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 KIK59250.1 - 0.049 12.6 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KIK59250.1 - 0.07 13.4 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIK59250.1 - 0.078 12.6 0.1 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KIK59250.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KIK59250.1 - 0.14 12.0 0.1 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Thymidylate_kin PF02223.17 KIK59250.1 - 0.17 11.5 0.0 3 7.5 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase CxC2 PF18803.1 KIK59252.1 - 0.018 15.2 0.1 0.021 15.0 0.1 1.1 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases DUF3483 PF11982.8 KIK59253.1 - 0.13 11.8 6.9 0.077 12.6 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) COX16 PF14138.6 KIK59253.1 - 0.31 11.6 0.7 8.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF2547 PF10818.8 KIK59256.1 - 0.26 12.2 3.1 0.58 11.1 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) SET PF00856.28 KIK59257.1 - 1.2e-10 42.0 0.0 1.2e-09 38.8 0.0 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KIK59257.1 - 0.024 15.3 0.0 3.5 8.3 0.0 2.5 2 0 0 2 2 2 0 SAF domain FAD_binding_1 PF00667.20 KIK59258.1 - 4.2e-55 186.7 0.0 1.3e-54 185.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIK59258.1 - 4.5e-31 108.0 0.5 4.5e-31 108.0 0.5 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KIK59258.1 - 4e-20 72.5 0.0 8.7e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FMO-like PF00743.19 KIK59259.1 - 2e-27 95.8 0.0 1.2e-26 93.3 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK59259.1 - 2.7e-22 79.4 0.0 3.2e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK59259.1 - 1.1e-14 54.4 0.0 1.8e-11 43.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK59259.1 - 6.2e-14 51.9 0.0 8.8e-11 41.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK59259.1 - 6.6e-07 29.8 0.1 0.024 15.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK59259.1 - 4.7e-06 26.7 0.0 0.0075 16.3 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KIK59259.1 - 9.9e-06 25.6 0.3 0.00097 19.2 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIK59259.1 - 8.8e-05 21.9 0.1 0.089 12.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIK59259.1 - 0.00013 22.2 0.1 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KIK59259.1 - 0.00029 20.6 0.0 1.4 8.4 0.0 3.4 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK59259.1 - 0.001 19.2 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK59259.1 - 0.0016 17.8 0.1 0.9 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KIK59259.1 - 0.0056 15.8 0.3 3.6 6.6 0.0 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KIK59259.1 - 0.014 15.8 0.0 0.44 11.0 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KIK59259.1 - 0.016 13.9 0.8 0.25 10.0 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein DUF498 PF04430.14 KIK59259.1 - 0.031 14.3 0.1 0.21 11.7 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF498/DUF598) ELFV_dehydrog PF00208.21 KIK59259.1 - 0.059 13.1 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Lycopene_cycl PF05834.12 KIK59259.1 - 0.061 12.4 0.2 1.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KIK59259.1 - 0.065 12.5 0.0 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.24 KIK59259.1 - 0.12 11.5 0.0 4.6 6.2 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain F420_oxidored PF03807.17 KIK59259.1 - 0.13 12.8 0.1 2.5 8.7 0.0 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIK59259.1 - 0.18 11.7 0.1 10 6.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Staph_opine_DH PF10100.9 KIK59259.1 - 0.22 10.1 0.1 1.2 7.8 0.0 1.9 2 0 0 2 2 2 0 Staphylopine dehydrogenase MoaE PF02391.17 KIK59260.1 - 0.00091 19.5 0.0 0.00097 19.4 0.0 1.0 1 0 0 1 1 1 1 MoaE protein GMC_oxred_N PF00732.19 KIK59261.1 - 6.8e-54 183.2 0.0 9.8e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK59261.1 - 4.2e-39 134.3 0.1 7.7e-39 133.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KIK59261.1 - 6.2e-05 22.3 0.2 0.0016 17.7 0.0 2.5 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 KIK59261.1 - 0.00025 20.7 0.0 0.00075 19.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK59261.1 - 0.0021 17.2 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK59261.1 - 0.0029 16.8 0.0 0.024 13.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK59261.1 - 0.0066 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK59261.1 - 0.0088 16.3 0.0 0.044 14.0 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK59261.1 - 0.041 13.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KIK59263.1 - 1.3e-51 175.8 0.0 1.8e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK59263.1 - 1.6e-37 129.2 0.1 2.9e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KIK59263.1 - 5.7e-05 22.5 0.1 0.002 17.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK59263.1 - 0.00025 20.7 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK59263.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK59263.1 - 0.0053 17.0 0.1 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK59263.1 - 0.0087 15.3 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK59263.1 - 0.015 14.4 0.0 0.048 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK59263.1 - 0.04 13.2 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK59264.1 - 6.9e-28 97.4 0.0 2e-19 69.4 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK59264.1 - 1.7e-24 86.7 0.0 2.3e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK59264.1 - 1.5e-18 67.1 0.0 8.9e-08 31.7 0.0 3.0 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK59264.1 - 9.1e-15 54.6 0.1 2.9e-10 39.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK59264.1 - 5.1e-08 33.4 0.0 0.022 15.3 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK59264.1 - 5.3e-06 26.5 0.5 0.0011 18.9 0.0 3.3 4 0 0 4 4 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIK59264.1 - 8.3e-06 25.9 0.0 0.026 14.6 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KIK59264.1 - 4.6e-05 23.6 0.0 0.017 15.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK59264.1 - 8.2e-05 22.0 0.0 0.07 12.5 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIK59264.1 - 0.00017 21.8 0.0 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KIK59264.1 - 0.00031 20.5 0.0 1.2 8.7 0.0 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK59264.1 - 0.00036 19.9 0.2 0.75 9.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain ELFV_dehydrog PF00208.21 KIK59264.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 KIK59264.1 - 0.0014 19.0 0.0 0.17 12.4 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.17 KIK59264.1 - 0.0016 19.0 0.0 0.19 12.3 0.0 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 KIK59264.1 - 0.0019 17.0 0.4 0.086 11.5 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein DUF498 PF04430.14 KIK59264.1 - 0.0041 17.2 0.6 0.15 12.1 0.0 3.3 5 0 0 5 5 4 1 Protein of unknown function (DUF498/DUF598) Lycopene_cycl PF05834.12 KIK59264.1 - 0.0042 16.2 0.2 0.52 9.3 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Phage_TAC_13 PF16459.5 KIK59264.1 - 0.07 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC GIDA PF01134.22 KIK59264.1 - 0.09 11.8 2.9 18 4.2 0.0 3.6 4 0 0 4 4 4 0 Glucose inhibited division protein A Thi4 PF01946.17 KIK59264.1 - 0.11 11.8 0.1 6.6 5.9 0.0 2.7 3 0 0 3 3 3 0 Thi4 family F-box-like PF12937.7 KIK59265.1 - 8.9e-06 25.5 0.9 3.9e-05 23.5 0.9 2.2 1 0 0 1 1 1 1 F-box-like cobW PF02492.19 KIK59267.1 - 2.5e-26 92.4 0.0 9.5e-26 90.4 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KIK59267.1 - 0.00055 19.0 0.1 0.021 13.8 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KIK59267.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIK59267.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK59267.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KIK59267.1 - 0.23 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Iwr1 PF08574.10 KIK59268.1 - 5e-11 43.4 10.0 5.3e-11 43.4 8.0 2.1 2 0 0 2 2 2 1 Transcription factor Iwr1 His_Phos_2 PF00328.22 KIK59269.1 - 0.00036 20.0 0.0 0.031 13.6 0.0 2.6 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) HCO3_cotransp PF00955.21 KIK59270.1 - 1.1e-70 238.9 11.7 2.2e-31 109.3 5.1 3.0 2 1 1 3 3 3 3 HCO3- transporter family F-box-like PF12937.7 KIK59272.1 - 3.3e-05 23.7 1.3 0.00013 21.8 1.3 2.1 1 0 0 1 1 1 1 F-box-like DUF1502 PF07397.11 KIK59275.1 - 0.49 10.3 4.5 8.4 6.3 0.3 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1502) F-box PF00646.33 KIK59276.1 - 4.9e-08 32.7 0.6 4.9e-08 32.7 0.6 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK59276.1 - 6.6e-06 25.9 0.2 2.8e-05 23.9 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK59276.1 - 0.0097 15.8 0.5 0.098 12.5 0.1 2.7 2 0 0 2 2 2 1 F-box Speriolin_C PF15059.6 KIK59276.1 - 0.04 14.1 0.7 0.5 10.5 0.3 2.7 1 1 2 3 3 3 0 Speriolin C-terminus Cys_Met_Meta_PP PF01053.20 KIK59278.1 - 2e-103 345.9 0.0 1.5e-79 267.3 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK59278.1 - 0.047 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Fungal_trans PF04082.18 KIK59279.1 - 8.6e-27 93.8 0.4 1.7e-26 92.9 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK59279.1 - 4.3e-08 33.1 8.5 6.9e-08 32.5 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.11 KIK59279.1 - 0.17 12.0 0.3 0.45 10.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) INCA1 PF15142.6 KIK59280.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 INCA1 MMR_HSR1 PF01926.23 KIK59281.1 - 1.7e-05 24.9 0.2 1.7e-05 24.9 0.2 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Caldesmon PF02029.15 KIK59281.1 - 3.2e-05 22.9 7.5 3.7e-05 22.7 7.5 1.1 1 0 0 1 1 1 1 Caldesmon IIGP PF05049.13 KIK59281.1 - 0.0014 17.7 0.1 0.0014 17.7 0.1 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 KIK59281.1 - 0.0065 16.6 0.2 0.0065 16.6 0.2 2.6 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 KIK59281.1 - 0.0068 16.9 0.0 0.0068 16.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 KIK59281.1 - 0.018 15.5 0.0 0.018 15.5 0.0 2.5 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 KIK59281.1 - 0.024 14.2 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KIK59281.1 - 0.026 14.8 3.4 0.058 13.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Gp-FAR-1 PF05823.12 KIK59281.1 - 0.042 14.2 16.5 0.071 13.5 14.9 1.9 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GAS PF13851.6 KIK59281.1 - 0.047 13.0 25.0 0.11 11.8 25.0 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SRPRB PF09439.10 KIK59281.1 - 0.053 12.9 0.0 0.053 12.9 0.0 3.0 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 KIK59281.1 - 0.12 12.8 0.9 1 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KIK59281.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain APG6_N PF17675.1 KIK59281.1 - 0.22 12.0 33.9 0.39 11.2 31.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KIK59281.1 - 0.23 11.7 28.4 0.12 12.6 24.9 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FapA PF03961.13 KIK59281.1 - 0.28 9.8 11.9 0.49 8.9 11.9 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_33 PF13671.6 KIK59281.1 - 0.36 11.0 3.0 0.77 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain FUSC PF04632.12 KIK59281.1 - 0.52 8.8 5.3 0.68 8.4 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATP_bind_1 PF03029.17 KIK59281.1 - 0.6 9.8 10.3 0.73 9.6 0.2 3.0 2 2 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 KIK59281.1 - 0.62 9.7 11.1 4.4 6.9 0.3 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 KIK59281.1 - 0.64 9.8 12.0 1.9 8.2 12.1 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK59281.1 - 0.72 9.9 21.3 0.19 11.8 1.1 4.0 2 2 1 3 3 2 0 Dynamin family ADIP PF11559.8 KIK59281.1 - 0.87 9.7 24.1 2.4 8.2 23.1 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DEK_C PF08766.11 KIK59281.1 - 1.4 8.9 9.4 0.16 12.0 1.2 2.9 3 0 0 3 3 2 0 DEK C terminal domain UPF0564 PF10595.9 KIK59281.1 - 1.5 7.8 20.2 2.2 7.3 20.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF4162 PF13732.6 KIK59281.1 - 1.5 9.6 7.3 0.59 10.9 3.4 2.3 2 2 0 2 2 1 0 Domain of unknown function (DUF4162) Presenilin PF01080.17 KIK59281.1 - 1.8 7.3 5.5 2.5 6.8 5.5 1.1 1 0 0 1 1 1 0 Presenilin CAF-1_p150 PF11600.8 KIK59281.1 - 2.1 8.0 31.7 3.4 7.3 31.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Lectin_N PF03954.14 KIK59281.1 - 2.7 7.8 10.1 0.62 9.8 5.7 2.3 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Snapin_Pallidin PF14712.6 KIK59281.1 - 3.9 8.0 16.0 0.083 13.3 4.9 2.5 1 1 1 2 2 2 0 Snapin/Pallidin G-alpha PF00503.20 KIK59281.1 - 5.3 6.1 9.6 2e+02 0.9 9.6 2.5 1 1 0 1 1 1 0 G-protein alpha subunit LCD1 PF09798.9 KIK59281.1 - 5.7 5.3 14.2 8.6 4.7 14.2 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4200 PF13863.6 KIK59281.1 - 6.4 7.2 32.9 0.76 10.2 28.2 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) MMR_HSR1 PF01926.23 KIK59283.1 - 6.1e-07 29.5 0.1 6.1e-07 29.5 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK59283.1 - 0.0047 17.5 5.5 0.021 15.3 0.0 2.5 2 1 0 2 2 2 1 ABC transporter DUF4407 PF14362.6 KIK59283.1 - 0.019 14.3 12.1 0.034 13.5 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gp-FAR-1 PF05823.12 KIK59283.1 - 0.024 15.0 10.0 0.042 14.2 10.0 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1640 PF07798.11 KIK59283.1 - 0.026 14.6 14.4 0.052 13.6 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FlaC_arch PF05377.11 KIK59283.1 - 0.028 14.8 3.8 0.29 11.6 1.2 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) PRP1_N PF06424.12 KIK59283.1 - 0.028 14.8 9.8 0.028 14.8 9.8 2.1 1 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Dynamin_N PF00350.23 KIK59283.1 - 0.045 13.8 18.8 0.094 12.8 0.5 3.9 2 2 2 4 4 4 0 Dynamin family APG6_N PF17675.1 KIK59283.1 - 0.051 14.1 32.7 0.18 12.3 32.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KIK59283.1 - 0.086 13.1 25.0 0.13 12.5 25.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KIK59283.1 - 0.8 9.2 9.2 1.3 8.5 9.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KIK59283.1 - 1 8.2 9.3 1.4 7.7 9.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4472 PF14739.6 KIK59283.1 - 1.2 9.9 21.4 3.4 8.4 20.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) CorA PF01544.18 KIK59283.1 - 1.4 8.2 9.0 2.1 7.6 9.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF5595 PF18077.1 KIK59283.1 - 1.5 8.9 10.6 2 8.6 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Ax_dynein_light PF10211.9 KIK59283.1 - 1.6 8.7 24.5 31 4.4 24.3 2.1 1 1 0 1 1 1 0 Axonemal dynein light chain Caldesmon PF02029.15 KIK59283.1 - 1.6 7.4 19.9 2.2 6.9 19.9 1.1 1 0 0 1 1 1 0 Caldesmon Fmp27_WPPW PF10359.9 KIK59283.1 - 1.7 7.4 12.8 2.5 6.8 12.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.19 KIK59283.1 - 1.8 6.4 8.9 2.5 5.9 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KIK59283.1 - 2.6 6.5 22.6 7.1 5.1 22.7 1.6 1 1 0 1 1 1 0 Macoilin family AAA_11 PF13086.6 KIK59283.1 - 4.9 6.9 10.8 7.7 6.2 10.8 1.3 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.6 KIK59283.1 - 5.8 6.2 11.5 15 4.8 11.5 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Jnk-SapK_ap_N PF09744.9 KIK59283.1 - 5.8 7.1 26.3 10 6.3 26.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 KIK59283.1 - 6.6 7.3 6.5 14 6.2 0.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 KIK59283.1 - 6.8 7.2 18.7 0.095 13.1 5.4 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Mod_r PF07200.13 KIK59283.1 - 7.2 6.7 25.8 78 3.3 25.8 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.6 KIK59283.1 - 8.5 6.8 29.0 28 5.2 29.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) SprA-related PF12118.8 KIK59283.1 - 9 5.3 14.6 14 4.7 14.6 1.2 1 0 0 1 1 1 0 SprA-related family MMR_HSR1 PF01926.23 KIK59285.1 - 2.3e-05 24.4 0.0 2.3e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase IIGP PF05049.13 KIK59285.1 - 0.00034 19.8 0.6 0.0013 17.9 0.2 2.0 1 1 1 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK59285.1 - 0.0029 18.1 0.0 0.0029 18.1 0.0 2.5 2 1 0 2 2 1 1 ABC transporter Rabaptin PF03528.15 KIK59285.1 - 0.015 14.0 15.8 0.021 13.6 15.8 1.1 1 0 0 1 1 1 0 Rabaptin RsgA_GTPase PF03193.16 KIK59285.1 - 0.021 14.7 1.8 0.067 13.1 0.4 2.5 2 1 0 2 2 2 0 RsgA GTPase LMBR1 PF04791.16 KIK59285.1 - 1.2 7.9 5.2 1.6 7.5 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DDRGK PF09756.9 KIK59285.1 - 1.3 8.6 22.6 2.2 7.8 22.6 1.4 1 0 0 1 1 1 0 DDRGK domain SOBP PF15279.6 KIK59285.1 - 1.3 9.5 5.5 1.9 9.0 5.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4407 PF14362.6 KIK59285.1 - 1.4 8.2 14.1 1.9 7.8 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KIK59285.1 - 1.5 7.3 12.3 2.2 6.8 12.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF87 PF01935.17 KIK59285.1 - 1.8 8.6 11.5 0.085 12.9 0.9 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain KBP_C PF12309.8 KIK59285.1 - 2.5 7.6 17.2 4.9 6.6 17.2 1.4 1 1 0 1 1 1 0 KIF-1 binding protein C terminal Dynamin_N PF00350.23 KIK59285.1 - 3.6 7.6 23.2 0.19 11.8 1.8 3.8 2 2 0 3 3 2 0 Dynamin family Phage_GP20 PF06810.11 KIK59285.1 - 4.1 7.2 20.7 10 5.9 20.7 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Oxidored_FMN PF00724.20 KIK59287.1 - 4.3e-70 236.7 0.0 5.2e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIK59287.1 - 0.0054 16.5 1.6 0.0081 15.9 0.2 2.0 2 0 0 2 2 2 1 Repeat of unknown function (DUF346) Oxidored_FMN PF00724.20 KIK59288.1 - 7.4e-71 239.2 0.0 9e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIK59288.1 - 0.0064 16.2 1.8 0.008 15.9 0.2 2.0 2 0 0 2 2 2 1 Repeat of unknown function (DUF346) F-box-like PF12937.7 KIK59289.1 - 9.6e-06 25.4 1.5 2.7e-05 24.0 1.5 1.8 1 1 0 1 1 1 1 F-box-like Rad50_zn_hook PF04423.14 KIK59289.1 - 0.073 12.9 0.2 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif FTSW_RODA_SPOVE PF01098.19 KIK59290.1 - 0.021 13.8 0.1 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Cell cycle protein RGS12_usC PF16612.5 KIK59290.1 - 0.047 14.1 0.2 0.083 13.3 0.2 1.4 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 YhhN PF07947.14 KIK59294.1 - 0.097 12.3 4.8 1.4 8.5 0.2 2.9 3 0 0 3 3 3 0 YhhN family Alpha_kinase PF02816.18 KIK59295.1 - 1.6e-12 47.9 0.1 3.5e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family rve PF00665.26 KIK59296.1 - 0.0015 18.8 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mor PF08765.11 KIK59296.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family RasGEF PF00617.19 KIK59298.1 - 4e-55 186.7 0.0 6.7e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK59298.1 - 3.7e-20 72.1 0.5 8.4e-20 71.0 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KIK59298.1 - 3.4e-15 55.4 0.1 7.1e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK59298.1 - 1.5e-12 47.2 0.1 2.8e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK59298.1 - 1.6e-11 43.7 0.0 3.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KIK59298.1 - 5.9e-08 32.7 0.3 0.005 16.9 0.2 2.6 2 0 0 2 2 2 2 WW domain Corona_nucleoca PF00937.18 KIK59298.1 - 0.41 9.6 6.1 0.098 11.7 0.4 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Glyoxal_oxid_N PF07250.11 KIK59299.1 - 6e-27 94.4 0.0 2.9e-26 92.1 0.0 2.1 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK59299.1 - 1.5e-21 76.5 0.0 4.8e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KIK59299.1 - 0.013 15.7 5.1 0.99 9.8 0.1 5.1 5 1 1 6 6 6 0 Kelch motif Kelch_4 PF13418.6 KIK59299.1 - 0.16 12.0 4.1 4.6 7.3 0.0 4.3 5 0 0 5 5 5 0 Galactose oxidase, central domain PTP_N PF12453.8 KIK59299.1 - 0.26 11.1 1.8 47 3.8 0.1 3.6 3 0 0 3 3 3 0 Protein tyrosine phosphatase N terminal Glyoxal_oxid_N PF07250.11 KIK59300.1 - 4.3e-26 91.6 0.0 1.8e-25 89.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK59300.1 - 3.3e-20 72.2 0.1 1.1e-19 70.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KIK59300.1 - 0.059 13.7 6.0 0.81 10.1 0.0 5.1 5 1 1 6 6 6 0 Kelch motif DASH_Dad1 PF08649.10 KIK59302.1 - 3.9e-22 78.2 0.5 4.7e-22 77.9 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KIK59302.1 - 0.022 14.7 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pkinase PF00069.25 KIK59303.1 - 1e-62 211.9 1.5 1.6e-62 211.3 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59303.1 - 4.8e-36 124.4 0.0 1.5e-35 122.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.16 KIK59303.1 - 5.6e-23 80.8 22.6 3.9e-14 52.5 5.4 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KIK59303.1 - 3.8e-20 71.5 29.8 1.6e-11 43.9 12.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KIK59303.1 - 1.3e-10 41.8 2.3 2.8e-10 40.7 0.7 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KIK59303.1 - 1.8e-06 28.2 0.0 3.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain C1_2 PF03107.16 KIK59303.1 - 0.82 10.0 23.1 3.8 7.9 6.5 2.4 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 KIK59303.1 - 1.3 9.2 13.7 1.2 9.3 2.2 2.9 2 1 0 2 2 2 0 Up-regulated During Septation Transp_cyt_pur PF02133.15 KIK59305.1 - 2.9e-44 151.6 35.4 3.8e-44 151.2 35.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Oxidored_q2 PF00420.24 KIK59305.1 - 0.53 10.0 10.1 3.9 7.2 0.6 2.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Dicty_CAR PF05462.11 KIK59307.1 - 0.096 11.8 6.2 0.06 12.5 3.1 1.8 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor MFS_1 PF07690.16 KIK59308.1 - 1.2e-39 136.3 38.2 1.2e-39 136.3 38.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK59308.1 - 0.0011 18.4 4.7 0.0011 18.4 4.7 3.0 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB DUF2244 PF10003.9 KIK59308.1 - 6.3 6.5 9.1 1.2 8.8 1.6 3.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Helicase_C_2 PF13307.6 KIK59311.1 - 7.6e-53 179.2 0.0 4.9e-52 176.6 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 KIK59311.1 - 1.4e-43 148.5 0.0 3.1e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KIK59311.1 - 0.0044 17.0 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CENP-Q PF13094.6 KIK59311.1 - 0.0082 16.4 1.8 0.0082 16.4 1.8 2.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DEAD PF00270.29 KIK59311.1 - 0.023 14.5 0.0 0.097 12.4 0.0 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 KIK59311.1 - 0.028 13.5 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KIK59311.1 - 0.075 12.5 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 KIK59311.1 - 0.09 12.6 0.9 1.2 8.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK59311.1 - 0.13 12.5 0.0 33 4.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK59311.1 - 0.14 11.8 0.6 0.63 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain Endosulfine PF04667.17 KIK59312.1 - 5e-26 90.6 0.2 8.6e-26 89.9 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region TP_methylase PF00590.20 KIK59319.1 - 5e-18 65.8 0.3 5e-08 33.1 0.0 2.8 2 1 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 KIK59319.1 - 4.6e-05 22.8 0.0 0.00015 21.2 0.0 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central LpqV PF17301.2 KIK59321.1 - 0.076 13.3 0.0 0.094 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative lipoprotein LpqV TP_methylase PF00590.20 KIK59323.1 - 1.3e-06 28.5 0.1 1.9e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4569 PF15133.6 KIK59324.1 - 0.01 15.6 1.7 0.011 15.5 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Syntaxin_2 PF14523.6 KIK59324.1 - 0.013 15.8 5.5 0.019 15.3 5.5 1.2 1 0 0 1 1 1 0 Syntaxin-like protein TP_methylase PF00590.20 KIK59328.1 - 1.4e-35 123.2 0.3 8.5e-19 68.3 0.1 2.6 3 0 0 3 3 3 2 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 KIK59328.1 - 4.8e-09 35.5 0.1 1e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 KIK59328.1 - 7.3e-09 36.0 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIK59328.1 - 8.9e-09 34.9 3.0 9.7e-08 31.5 0.3 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal NmrA PF05368.13 KIK59329.1 - 2.1e-28 99.4 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK59329.1 - 9.9e-10 38.6 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK59329.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GTP_EFTU PF00009.27 KIK59331.1 - 1.3e-55 188.0 0.1 2.8e-55 186.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIK59331.1 - 7.4e-17 61.2 0.0 2.6e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIK59331.1 - 7.6e-05 22.7 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KIK59331.1 - 7.9e-05 22.7 0.1 0.00015 21.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KIK59331.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU_D2 PF03144.25 KIK59331.1 - 0.031 14.7 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Ras PF00071.22 KIK59331.1 - 0.034 13.7 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras family EFG_IV PF03764.18 KIK59331.1 - 0.083 12.7 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Elongation factor G, domain IV DUF3429 PF11911.8 KIK59333.1 - 7.1e-39 133.4 15.5 1e-38 132.9 15.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) WD40 PF00400.32 KIK59334.1 - 3.1e-21 75.3 11.9 4.8e-11 43.0 0.6 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59334.1 - 7.8e-07 29.3 0.0 0.0021 18.3 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59334.1 - 9.7e-05 21.5 0.7 0.041 12.8 0.4 2.8 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59334.1 - 0.00035 20.4 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59334.1 - 0.016 13.9 3.1 0.37 9.4 0.4 2.8 1 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK59334.1 - 0.065 12.5 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 WD40-like domain PQQ PF01011.21 KIK59334.1 - 0.08 12.9 0.1 16 5.6 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK59334.1 - 0.11 11.3 0.3 0.99 8.1 0.0 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4072 PF13284.6 KIK59334.1 - 0.18 12.2 0.1 21 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) WD40 PF00400.32 KIK59335.1 - 2.8e-09 37.4 1.5 9.2e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.12 KIK59335.1 - 5.3e-05 23.2 0.4 0.00019 21.4 0.4 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK59335.1 - 0.00028 21.3 0.0 0.012 15.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KIK59335.1 - 0.01 16.1 0.1 0.19 12.0 0.0 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin_15 PF18403.1 KIK59335.1 - 0.043 13.7 1.4 0.11 12.4 0.0 2.3 2 2 0 2 2 2 0 Thioredoxin-like domain Mito_morph_reg PF14972.6 KIK59335.1 - 0.09 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator MiaE_2 PF13794.6 KIK59335.1 - 0.1 12.3 0.5 4 7.1 0.0 2.3 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like AAA_33 PF13671.6 KIK59335.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK59335.1 - 0.12 12.6 0.0 0.96 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 KIK59337.1 - 1.3e-82 269.5 54.7 2e-10 41.1 0.7 9.6 10 0 0 10 10 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59337.1 - 7.9e-32 109.4 0.0 0.0047 17.2 0.0 8.2 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59337.1 - 4.1e-20 72.0 3.5 0.025 13.6 0.0 8.1 2 1 5 8 8 8 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59337.1 - 2.6e-16 59.1 10.1 1.2 9.2 0.1 8.7 8 0 0 8 8 8 6 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59337.1 - 9.9e-09 34.4 6.3 4.6 5.8 0.0 8.1 8 1 1 9 9 9 3 Nucleoporin Nup120/160 ATP-sulfurylase PF01747.17 KIK59337.1 - 9.5e-08 31.8 0.1 6.8 6.1 0.0 6.1 7 0 0 7 7 7 1 ATP-sulfurylase Frtz PF11768.8 KIK59337.1 - 3e-07 29.2 0.0 2.5 6.3 0.0 6.0 3 2 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK59337.1 - 1e-06 28.3 0.0 15 4.8 0.0 6.6 7 1 0 7 7 7 0 WD40-like domain PQQ PF01011.21 KIK59337.1 - 0.00057 19.7 4.0 36 4.5 0.0 7.1 8 0 0 8 8 8 0 PQQ enzyme repeat PQQ_2 PF13360.6 KIK59337.1 - 0.0034 17.0 12.8 0.6 9.6 8.0 5.0 1 1 2 3 3 3 1 PQQ-like domain rOmpB PF12334.8 KIK59337.1 - 0.0071 15.9 10.3 24 4.3 0.1 6.5 5 2 1 7 7 7 0 Rickettsia outer membrane protein B DUF1652 PF07865.11 KIK59337.1 - 0.017 15.0 0.1 11 6.0 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) Me-amine-dh_H PF06433.11 KIK59337.1 - 0.033 13.1 0.0 15 4.3 0.0 3.5 1 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) WD40_3 PF15911.5 KIK59337.1 - 0.034 14.1 4.9 28 4.8 0.1 5.8 7 0 0 7 7 7 0 WD domain, G-beta repeat IF4E PF01652.18 KIK59337.1 - 0.075 12.8 0.0 18 5.1 0.0 3.3 3 0 0 3 3 3 0 Eukaryotic initiation factor 4E Methyltransf_10 PF05971.12 KIK59337.1 - 0.15 11.4 1.1 1.5 8.1 0.1 2.7 2 1 1 3 3 3 0 RNA methyltransferase Proteasome_A_N PF10584.9 KIK59337.1 - 1.2 8.8 17.3 98 2.8 0.0 7.6 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KIK59338.1 - 0.00079 19.8 0.0 0.00098 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK59338.1 - 0.0058 16.5 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 NTPase NACHT PF05729.12 KIK59338.1 - 0.0067 16.4 0.4 0.024 14.6 0.4 1.8 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 KIK59338.1 - 0.014 15.5 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK59338.1 - 0.02 14.8 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK59338.1 - 0.022 15.0 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK59338.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KIK59338.1 - 0.055 12.6 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KIK59338.1 - 0.062 13.1 0.2 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIK59338.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KIK59338.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK59338.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KIK59338.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KIK59338.1 - 0.26 11.8 0.6 0.29 11.7 0.6 1.4 1 1 0 1 1 1 0 AAA domain DUF3429 PF11911.8 KIK59339.1 - 1.4e-16 61.1 10.9 1.8e-15 57.5 10.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3429) WD40 PF00400.32 KIK59340.1 - 7.1e-28 96.3 18.1 2.5e-10 40.7 0.6 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59340.1 - 3.3e-09 36.9 0.0 0.062 13.6 0.0 3.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK59340.1 - 6.7e-05 22.7 0.4 1.6 8.8 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK59340.1 - 0.0001 21.4 0.1 0.23 10.4 0.0 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK59340.1 - 0.0003 20.2 0.0 0.036 13.4 0.0 2.1 1 1 1 2 2 2 2 WD40-like domain ATP-sulfurylase PF01747.17 KIK59340.1 - 0.055 12.9 0.0 19 4.6 0.0 2.9 3 0 0 3 3 3 0 ATP-sulfurylase Nbas_N PF15492.6 KIK59340.1 - 0.069 12.5 0.8 5.2 6.3 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal 2OG-FeII_Oxy_5 PF13759.6 KIK59340.1 - 0.09 13.2 0.7 75 3.8 0.1 3.1 3 0 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase PQQ PF01011.21 KIK59340.1 - 0.11 12.5 1.1 39 4.4 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat rOmpB PF12334.8 KIK59340.1 - 0.11 11.9 0.7 8.3 5.8 0.1 2.8 1 1 2 3 3 3 0 Rickettsia outer membrane protein B AAA_16 PF13191.6 KIK59341.1 - 9.1e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK59341.1 - 0.0049 16.8 0.3 0.018 15.0 0.3 1.8 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK59341.1 - 0.015 14.5 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KIK59341.1 - 0.028 14.6 0.1 0.051 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK59341.1 - 0.037 13.9 0.1 0.058 13.3 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK59341.1 - 0.038 13.9 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 NTPase PhoH PF02562.16 KIK59341.1 - 0.049 13.1 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KIK59341.1 - 0.055 14.0 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK59341.1 - 0.082 13.3 0.0 0.14 12.6 0.0 1.6 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 KIK59341.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK59341.1 - 0.093 12.4 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK59341.1 - 0.096 12.4 0.2 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KIK59341.1 - 0.13 12.7 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KIK59341.1 - 0.14 12.0 0.2 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KIK59341.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3429 PF11911.8 KIK59342.1 - 0.00027 21.2 5.6 0.0033 17.7 5.5 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3429) CD20 PF04103.15 KIK59343.1 - 0.0071 16.4 0.1 0.0098 16.0 0.0 1.5 1 1 0 1 1 1 1 CD20-like family DUF3094 PF11293.8 KIK59343.1 - 0.079 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) p450 PF00067.22 KIK59344.1 - 1.1e-83 281.6 0.0 1.2e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTV_P6 PF06706.11 KIK59345.1 - 0.012 15.3 1.7 0.034 13.8 1.7 1.7 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Atthog PF18800.1 KIK59345.1 - 0.11 12.3 11.8 0.5 10.3 2.0 2.2 1 1 1 2 2 2 0 Attenuator of Hedgehog RIBIOP_C PF04950.12 KIK59346.1 - 3.7e-81 272.8 0.0 2.6e-80 270.0 0.0 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIK59346.1 - 1.2e-30 105.5 0.0 4.8e-30 103.5 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KIK59346.1 - 2.3e-05 24.7 0.3 6.9e-05 23.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KIK59346.1 - 6.5e-05 23.4 0.0 0.00024 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIK59346.1 - 0.0004 20.6 1.2 0.00085 19.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KIK59346.1 - 0.00045 19.8 1.3 0.049 13.2 0.0 2.6 2 1 0 3 3 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KIK59346.1 - 0.00068 20.2 2.8 0.00083 19.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 KIK59346.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KIK59346.1 - 0.0018 18.3 0.1 0.0061 16.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KIK59346.1 - 0.0024 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIK59346.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK59346.1 - 0.011 16.1 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK59346.1 - 0.011 16.3 0.2 0.011 16.3 0.2 2.5 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KIK59346.1 - 0.012 14.9 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KIK59346.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK59346.1 - 0.02 15.2 0.1 0.054 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK59346.1 - 0.025 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK59346.1 - 0.025 14.6 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK59346.1 - 0.027 14.8 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIK59346.1 - 0.033 13.8 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIK59346.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIK59346.1 - 0.058 13.1 0.0 0.058 13.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KIK59346.1 - 0.079 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK59346.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KIK59346.1 - 0.4 10.6 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KIK59346.1 - 0.45 11.0 8.3 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MCRA PF06100.11 KIK59346.1 - 0.72 8.6 2.4 1 8.0 2.4 1.2 1 0 0 1 1 1 0 MCRA family SRP54 PF00448.22 KIK59346.1 - 3.5 7.2 6.4 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 KIK59346.1 - 8.6 6.1 16.1 0.79 9.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain Annexin PF00191.20 KIK59347.1 - 7.6e-61 202.1 1.3 1.1e-16 60.6 0.0 4.3 4 0 0 4 4 4 4 Annexin OST-HTH PF12872.7 KIK59347.1 - 0.0078 16.0 1.9 1.1 9.1 0.0 3.2 4 0 0 4 4 4 2 OST-HTH/LOTUS domain 2Fe-2S_thioredx PF01257.19 KIK59348.1 - 0.11 12.3 0.3 0.65 9.9 0.3 2.0 1 1 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Sugar_tr PF00083.24 KIK59349.1 - 0.00027 19.9 2.8 0.00063 18.7 2.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KIK59352.1 - 4.5e-49 167.5 10.8 6.3e-49 167.1 10.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK59352.1 - 1.3e-21 77.0 25.8 2.1e-21 76.3 25.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK59353.1 - 6.2e-18 64.8 32.1 6.2e-18 64.8 32.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK59353.1 - 7.3e-08 31.7 3.6 7.3e-08 31.7 3.6 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRIQK PF15168.6 KIK59353.1 - 0.47 10.4 1.8 0.92 9.5 0.1 2.2 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Myb_DNA-bind_2 PF08914.11 KIK59354.1 - 2e-10 40.7 1.5 5.7e-10 39.2 1.4 1.8 1 1 0 1 1 1 1 Rap1 Myb domain cobW PF02492.19 KIK59356.1 - 1.4e-43 148.6 0.0 1.8e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIK59356.1 - 6.2e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.23 KIK59356.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KIK59356.1 - 0.0051 17.0 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK59356.1 - 0.0077 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK59356.1 - 0.011 15.6 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KIK59356.1 - 0.021 14.4 1.9 0.97 8.9 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 KIK59356.1 - 0.083 11.9 0.0 0.46 9.4 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KIK59356.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pkinase_Tyr PF07714.17 KIK59358.1 - 3.2e-39 134.8 0.0 4.4e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK59358.1 - 2.3e-32 112.4 0.0 3.8e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK59358.1 - 0.01 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ADH_N PF08240.12 KIK59359.1 - 4.7e-24 84.4 0.3 9.6e-24 83.4 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK59359.1 - 1.1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DSPc PF00782.20 KIK59360.1 - 9.8e-26 90.1 0.0 1.6e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK59360.1 - 0.0083 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain UAA PF08449.11 KIK59361.1 - 5.1e-44 150.7 9.2 1.2e-42 146.2 7.6 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KIK59361.1 - 2.5e-07 30.9 24.7 8.1e-07 29.3 6.8 4.2 2 2 3 5 5 5 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KIK59361.1 - 0.011 14.9 1.5 1.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter TPT PF03151.16 KIK59361.1 - 0.024 14.0 5.7 0.13 11.6 0.7 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family CRT-like PF08627.10 KIK59361.1 - 0.025 13.5 5.9 1.2 8.0 0.6 2.4 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like PsbN PF02468.15 KIK59361.1 - 0.09 12.6 0.2 5 7.0 0.0 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) BCS1_N PF08740.11 KIK59362.1 - 7.3e-09 35.9 0.5 6.9e-06 26.2 0.2 2.6 1 1 0 1 1 1 1 BCS1 N terminal YlbE PF14003.6 KIK59362.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 YlbE-like protein ETRAMP PF09716.10 KIK59363.1 - 0.12 12.5 1.2 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_23 PF13489.6 KIK59365.1 - 1.7e-13 50.7 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK59365.1 - 1.9e-12 47.8 0.0 4.7e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK59365.1 - 1.3e-10 41.8 0.0 3.1e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK59365.1 - 1.9e-09 38.0 0.0 3.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK59365.1 - 0.0001 22.1 0.0 0.0006 19.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK59365.1 - 0.0015 18.1 0.0 0.0064 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KIK59365.1 - 0.0025 17.0 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KIK59365.1 - 0.0042 16.9 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 KIK59365.1 - 0.049 14.7 0.0 0.096 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 KIK59366.1 - 0.0014 18.4 0.7 0.0068 16.3 0.7 2.2 1 0 0 1 1 1 1 F-box-like DUF2427 PF10348.9 KIK59371.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) BBS2_N PF14781.6 KIK59372.1 - 0.0034 17.2 0.0 9.7 6.2 0.0 3.5 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.32 KIK59372.1 - 0.012 16.4 6.9 0.43 11.5 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Ank_2 PF12796.7 KIK59373.1 - 6.1e-11 42.8 0.0 6.6e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK59373.1 - 2.9e-07 30.6 0.0 0.35 11.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK59373.1 - 0.0011 19.5 0.0 0.026 15.1 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK59373.1 - 0.0022 18.4 0.1 14 6.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 KIK59373.1 - 0.12 12.4 0.0 0.78 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) SKG6 PF08693.10 KIK59374.1 - 0.0084 15.5 1.1 0.017 14.5 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 KIK59374.1 - 0.078 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless GalKase_gal_bdg PF10509.9 KIK59375.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature DUF5373 PF17343.2 KIK59376.1 - 0.17 11.7 8.3 0.22 11.4 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF5090 PF17009.5 KIK59376.1 - 9.8 6.1 13.5 12 5.9 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) GalKase_gal_bdg PF10509.9 KIK59378.1 - 0.035 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature IMUP PF15761.5 KIK59378.1 - 0.87 10.3 8.6 2.3 9.0 8.6 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein CoA_transf_3 PF02515.17 KIK59379.1 - 3.2e-116 388.5 0.0 3.7e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF3552 PF12072.8 KIK59380.1 - 5.2e-07 29.3 114.6 0.00048 19.6 26.2 5.5 2 2 3 5 5 5 4 Domain of unknown function (DUF3552) Ank_4 PF13637.6 KIK59381.1 - 7.7e-22 77.4 4.4 1.4e-08 35.1 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK59381.1 - 4.5e-21 75.2 5.0 1.2e-10 41.8 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KIK59381.1 - 2.1e-16 59.5 5.2 0.00071 19.9 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KIK59381.1 - 2.8e-14 51.8 0.6 0.0017 18.6 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK59381.1 - 4.9e-13 49.0 1.5 0.0016 18.7 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) BBP2 PF07642.11 KIK59381.1 - 0.012 14.8 0.3 0.015 14.5 0.2 1.3 1 1 0 1 1 1 0 Putative beta-barrel porin-2, OmpL-like. bbp2 Stanniocalcin PF03298.13 KIK59381.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Stanniocalcin family DUF1843 PF08898.10 KIK59381.1 - 1.4 9.5 6.3 33 5.1 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) Ank_4 PF13637.6 KIK59382.1 - 5.9e-14 52.2 0.3 7.2e-08 32.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK59382.1 - 3.4e-10 40.3 0.3 1.8e-09 38.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK59382.1 - 2e-09 37.4 1.1 0.00079 19.8 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIK59382.1 - 4.2e-07 29.8 0.1 0.029 14.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIK59382.1 - 0.00025 21.3 0.1 0.19 12.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KIK59382.1 - 0.047 13.6 0.2 6.5 6.7 0.1 2.1 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain HicA_toxin PF07927.12 KIK59382.1 - 0.1 12.6 0.0 5.4 7.1 0.0 2.1 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Nucleopor_Nup85 PF07575.13 KIK59382.1 - 0.18 10.4 0.0 0.21 10.1 0.0 1.0 1 0 0 1 1 1 0 Nup85 Nucleoporin Ank_2 PF12796.7 KIK59383.1 - 2.1e-10 41.0 0.3 2.6e-10 40.7 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK59383.1 - 4.1e-10 40.0 0.7 5.4e-10 39.6 0.4 1.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK59383.1 - 4.4e-08 32.8 0.9 0.00023 21.3 0.1 2.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIK59383.1 - 1.9e-07 31.2 5.0 0.00052 20.3 0.3 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK59383.1 - 0.00017 21.8 0.5 0.047 14.0 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 KIK59383.1 - 0.0042 17.0 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) DUF1843 PF08898.10 KIK59383.1 - 0.096 13.2 1.1 6.7 7.3 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) PYC_OADA PF02436.18 KIK59383.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain Transket_pyr PF02779.24 KIK59384.1 - 9.2e-68 227.4 0.0 1.6e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIK59384.1 - 1.8e-60 204.4 0.0 2.6e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KIK59384.1 - 6e-52 175.4 0.0 1.2e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KIK59384.1 - 2.1e-19 68.8 0.4 4.4e-19 67.8 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus GPI-anchored PF10342.9 KIK59385.1 - 0.00015 22.4 0.3 0.00021 22.0 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KIK59386.1 - 0.00043 21.0 0.6 0.00077 20.2 0.6 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hpt PF01627.23 KIK59389.1 - 5.2e-13 49.1 0.2 6.6e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 Hpt domain Pkinase_Tyr PF07714.17 KIK59390.1 - 2.9e-38 131.7 0.0 3.9e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK59390.1 - 3.7e-32 111.7 0.0 5.4e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK59390.1 - 0.0019 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK59390.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family HpcH_HpaI PF03328.14 KIK59391.1 - 2.4e-37 128.2 0.0 7.5e-37 126.6 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KIK59391.1 - 7.2e-14 51.7 0.0 1e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold GPI-anchored PF10342.9 KIK59393.1 - 0.00071 20.3 0.1 0.001 19.7 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NTP_transf_9 PF04248.12 KIK59394.1 - 1.3e-25 89.1 0.4 1.4e-25 89.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) AMP-binding PF00501.28 KIK59395.1 - 6e-79 265.6 0.0 7.6e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK59395.1 - 1.1e-15 58.3 2.5 1.1e-14 55.1 0.3 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain DAP3 PF10236.9 KIK59396.1 - 0.039 13.1 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MeaB PF03308.16 KIK59396.1 - 0.078 12.0 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FoP_duplication PF13865.6 KIK59399.1 - 4.4 7.9 5.8 14 6.4 5.8 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4448 PF14610.6 KIK59400.1 - 0.00028 20.7 2.0 0.0013 18.6 2.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1180 PF06679.12 KIK59400.1 - 0.00033 21.1 2.1 0.00033 21.1 2.1 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1180) Glycophorin_A PF01102.18 KIK59400.1 - 0.025 14.8 0.4 0.098 12.9 0.5 2.0 2 0 0 2 2 2 0 Glycophorin A TMEM154 PF15102.6 KIK59400.1 - 0.13 12.1 0.0 0.51 10.2 0.0 1.9 1 1 1 2 2 2 0 TMEM154 protein family Macoilin PF09726.9 KIK59400.1 - 9.9 4.6 7.3 14 4.1 7.3 1.2 1 0 0 1 1 1 0 Macoilin family BC10 PF06726.12 KIK59401.1 - 0.04 14.1 1.2 2.1 8.6 0.0 2.7 3 0 0 3 3 3 0 Bladder cancer-related protein BC10 AMP-binding PF00501.28 KIK59402.1 - 1e-73 248.4 0.0 1.2e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK59402.1 - 6.3e-16 59.1 0.0 1.8e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 KIK59403.1 - 5.5e-70 231.4 1.1 7.7e-26 89.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arfaptin PF06456.13 KIK59403.1 - 0.17 11.4 0.0 5.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Arfaptin-like domain Serine_protease PF18405.1 KIK59403.1 - 0.47 9.6 3.0 44 3.1 0.0 3.9 3 2 1 4 4 4 0 Gammaproteobacterial serine protease F-box-like PF12937.7 KIK59404.1 - 0.0066 16.3 1.0 0.017 15.0 1.0 1.7 1 0 0 1 1 1 1 F-box-like FMO-like PF00743.19 KIK59405.1 - 0.0003 19.3 0.0 0.0016 17.0 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Aminotran_1_2 PF00155.21 KIK59407.1 - 1.6e-31 109.8 0.0 2.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 KIK59408.1 - 1.4e-13 51.0 8.4 2.6e-05 24.9 1.4 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK59408.1 - 0.0093 15.0 0.2 1.5 7.7 0.0 2.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59408.1 - 0.78 9.8 6.0 8.3 6.5 0.1 3.7 3 2 0 3 3 3 0 WD40-like Beta Propeller Repeat Mito_fiss_reg PF05308.11 KIK59410.1 - 1.1 9.3 4.5 1.7 8.7 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator BTB PF00651.31 KIK59411.1 - 0.024 14.8 0.0 0.051 13.8 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain Headcase PF16002.5 KIK59411.1 - 0.12 11.8 0.1 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Headcase protein Arginase PF00491.21 KIK59412.1 - 1.3e-76 257.8 0.0 1.6e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family WD40 PF00400.32 KIK59413.1 - 7.7e-95 308.2 52.8 2e-09 37.9 2.5 13.1 11 2 2 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59413.1 - 1.7e-30 105.2 0.0 0.0013 19.0 0.0 10.7 2 1 10 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59413.1 - 3.6e-18 65.6 15.2 0.015 14.3 0.0 11.0 4 2 8 12 12 12 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59413.1 - 6.6e-18 64.2 20.1 0.26 11.3 0.2 10.3 11 0 0 11 11 11 6 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59413.1 - 1.4e-09 37.2 0.7 0.85 8.2 0.0 7.5 10 0 0 10 10 10 3 Nucleoporin Nup120/160 Gmad1 PF10647.9 KIK59413.1 - 3.5e-07 30.2 16.5 0.0069 16.2 0.9 8.7 2 1 3 6 6 6 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 KIK59413.1 - 5.7e-06 25.9 8.0 2.7 7.3 0.1 6.9 7 2 1 8 8 8 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK59413.1 - 0.00057 19.3 0.0 2.3 7.5 0.0 4.8 5 0 0 5 5 5 1 WD40-like domain Peptidase_S9_N PF02897.15 KIK59413.1 - 0.0012 17.7 0.0 20 3.8 0.0 4.7 4 0 0 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DHFR_2 PF06442.11 KIK59413.1 - 0.08 12.8 0.4 24 4.8 0.1 3.0 2 1 0 2 2 2 0 R67 dihydrofolate reductase DUF4265 PF14085.6 KIK59413.1 - 0.11 12.5 0.0 8.4 6.4 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4265) FCP1_C PF09309.10 KIK59413.1 - 0.29 11.0 0.0 25 4.6 0.0 3.5 3 1 0 4 4 4 0 FCP1, C-terminal Cuticle_4 PF15955.5 KIK59413.1 - 0.55 11.0 4.0 1.9e+02 2.8 0.0 5.3 7 0 0 7 7 5 0 Cuticle protein Proteasome_A_N PF10584.9 KIK59413.1 - 3 7.6 17.9 20 5.0 0.2 7.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK59414.1 - 4e-93 302.8 50.0 1.5e-09 38.3 0.2 12.3 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59414.1 - 3.5e-32 110.6 0.5 0.015 15.5 0.0 11.0 3 3 8 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59414.1 - 9.5e-27 93.8 13.3 0.042 12.8 0.0 11.7 2 2 9 12 12 12 10 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK59414.1 - 2.4e-16 59.2 21.8 0.95 9.5 0.2 11.5 12 0 0 12 12 12 7 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK59414.1 - 2.2e-11 43.1 2.9 0.03 13.0 0.0 7.1 8 0 0 8 8 8 4 Nucleoporin Nup120/160 Gmad1 PF10647.9 KIK59414.1 - 1.2e-07 31.8 12.0 0.17 11.6 0.2 7.5 1 1 1 3 3 3 3 Lipoprotein LpqB beta-propeller domain Frtz PF11768.8 KIK59414.1 - 0.0031 15.9 0.0 3.4 5.9 0.0 4.2 4 1 1 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Robl_LC7 PF03259.17 KIK59414.1 - 0.0039 16.9 0.1 40 4.1 0.0 4.5 5 0 0 5 5 5 0 Roadblock/LC7 domain bPH_4 PF06713.11 KIK59414.1 - 0.0043 17.1 0.0 2.7 8.1 0.0 4.2 4 1 0 4 4 4 1 Bacterial PH domain DUF727 PF05303.12 KIK59414.1 - 0.01 15.9 0.0 7.6 6.7 0.0 4.7 5 1 3 8 8 8 0 Protein of unknown function (DUF727) RNA_helicase PF00910.22 KIK59415.1 - 0.0012 19.2 0.0 0.0014 19.0 0.0 1.1 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KIK59415.1 - 0.002 18.6 0.0 0.002 18.6 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIK59415.1 - 0.0045 17.2 0.0 0.0057 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK59415.1 - 0.011 15.3 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KIK59415.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 KIK59415.1 - 0.015 15.8 0.0 0.019 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK59415.1 - 0.018 15.0 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIK59415.1 - 0.021 14.0 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KIK59415.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK59415.1 - 0.026 14.8 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIK59415.1 - 0.028 14.8 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK59415.1 - 0.041 14.3 0.0 0.047 14.1 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK59415.1 - 0.052 13.3 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 KIK59415.1 - 0.062 13.0 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 KIK59415.1 - 0.067 12.9 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK59415.1 - 0.12 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIK59415.1 - 0.13 12.1 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK59415.1 - 0.17 10.9 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KIK59415.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KIK59415.1 - 0.22 12.0 0.0 0.3 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KIK59415.1 - 0.25 11.4 0.0 0.33 11.0 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 KIK59416.1 - 1.1e-05 25.5 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK59416.1 - 0.0017 18.7 0.0 0.0025 18.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK59416.1 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KIK59416.1 - 0.0091 16.5 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK59416.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK59416.1 - 0.021 15.1 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK59416.1 - 0.037 14.4 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK59416.1 - 0.049 13.5 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KIK59416.1 - 0.056 12.6 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KIK59416.1 - 0.062 12.8 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KIK59416.1 - 0.087 12.5 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 KIK59416.1 - 0.097 13.1 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK59416.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 KIK59416.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK59416.1 - 0.17 11.8 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea BNR_2 PF13088.6 KIK59418.1 - 1e-14 54.5 5.7 6.1e-07 29.0 0.2 2.4 1 1 2 3 3 3 3 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KIK59418.1 - 7e-05 21.8 3.1 0.099 11.4 0.0 2.7 1 1 2 3 3 3 2 Sortilin, neurotensin receptor 3, BNR_4 PF15892.5 KIK59418.1 - 0.005 16.2 0.5 0.8 9.0 0.1 2.4 1 1 2 3 3 3 2 BNR repeat-containing family member BNR PF02012.20 KIK59418.1 - 0.029 14.3 12.8 5.1 7.5 0.4 4.8 4 0 0 4 4 4 0 BNR/Asp-box repeat Zn_clus PF00172.18 KIK59419.1 - 1.3e-05 25.2 9.1 2.4e-05 24.4 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VSP PF03302.13 KIK59419.1 - 0.0047 15.8 0.4 0.0061 15.5 0.4 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein AT_hook PF02178.19 KIK59420.1 - 1.2 9.2 8.3 0.17 11.8 3.7 2.1 2 0 0 2 2 2 0 AT hook motif MFS_1 PF07690.16 KIK59421.1 - 4.6e-35 121.2 30.9 4.6e-35 121.2 30.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PRT_C PF08372.10 KIK59421.1 - 0.0068 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Delta_lysin PF05372.11 KIK59421.1 - 0.058 12.7 0.4 0.12 11.7 0.4 1.5 1 0 0 1 1 1 0 Delta lysin family YpmT PF17431.2 KIK59421.1 - 8.5 6.5 7.9 0.32 11.1 0.7 2.5 3 0 0 3 3 3 0 Uncharacterized YmpT-like PikAIV_N PF18605.1 KIK59422.1 - 0.87 9.2 9.0 0.14 11.8 0.4 3.1 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF5059 PF16502.5 KIK59423.1 - 0.095 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5059) DUF4203 PF13886.6 KIK59424.1 - 0.63 9.7 8.4 0.3 10.7 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) CD52 PF15116.6 KIK59427.1 - 0.17 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 CAMPATH-1 antigen Peroxidase_2 PF01328.17 KIK59428.1 - 6.7e-52 176.7 0.0 8.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Dimer_Tnp_hAT PF05699.14 KIK59429.1 - 0.0043 16.8 0.1 0.0055 16.5 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region YaeQ PF07152.12 KIK59429.1 - 0.17 11.5 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 YaeQ protein Ribosomal_L7Ae PF01248.26 KIK59431.1 - 2.8e-28 97.5 2.5 3.5e-28 97.2 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4911 PF16256.5 KIK59431.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Acetyltransf_3 PF13302.7 KIK59432.1 - 1.5e-15 58.1 0.0 1.9e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK59432.1 - 1.5e-09 38.1 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIK59432.1 - 9e-08 32.4 0.0 1.2e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK59432.1 - 2.4e-06 27.5 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK59432.1 - 1.6e-05 24.7 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIK59432.1 - 5.2e-05 23.0 0.0 8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK59432.1 - 6.8e-05 23.2 0.0 9.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.7 KIK59434.1 - 3.8e-06 26.7 0.1 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK59434.1 - 0.11 13.0 10.3 15 6.2 0.6 5.6 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Glycolytic PF00274.19 KIK59435.1 - 1.2e-67 228.2 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I F-box-like PF12937.7 KIK59436.1 - 8.5e-06 25.6 0.2 1.3e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 F-box-like Putative_PNPOx PF01243.20 KIK59437.1 - 1.6e-23 82.7 0.0 3.4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KIK59437.1 - 5.2e-18 64.9 2.1 1.1e-17 63.8 2.1 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KIK59437.1 - 3.2e-05 24.5 0.0 5.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KIK59437.1 - 0.0061 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like HMMR_C PF15908.5 KIK59437.1 - 0.014 15.7 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Birna_VP5 PF03042.14 KIK59439.1 - 0.05 13.6 0.2 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Birnavirus VP5 protein Hydrophobin PF01185.18 KIK59441.1 - 1.1e-20 74.0 6.9 1.3e-20 73.8 6.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Sugar_tr PF00083.24 KIK59442.1 - 4.2e-78 263.2 24.8 5.2e-78 262.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK59442.1 - 1.2e-18 67.2 40.4 2.3e-15 56.4 16.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4139 PF13598.6 KIK59443.1 - 1.1e-34 120.1 0.3 2.8e-34 118.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIK59443.1 - 1.6e-18 66.9 0.5 2e-17 63.4 0.5 2.4 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF4139 PF13598.6 KIK59446.1 - 2.4e-26 92.8 0.1 4.9e-26 91.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIK59446.1 - 6e-15 55.5 0.0 2.5e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Thioredoxin_13 PF18401.1 KIK59446.1 - 0.04 13.8 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain CARDB PF07705.11 KIK59446.1 - 0.052 13.8 0.1 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 CARDB TPR_10 PF13374.6 KIK59447.1 - 1.6e-15 56.4 0.0 4.3e-06 26.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK59447.1 - 3.6e-13 49.6 0.0 2.9e-11 43.5 0.0 2.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK59447.1 - 7.5e-06 25.6 0.0 0.00086 19.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK59447.1 - 3.8e-05 23.5 0.0 0.014 15.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK59447.1 - 0.00011 21.9 0.1 0.0031 17.4 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK59447.1 - 0.00035 20.6 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK59447.1 - 0.011 16.4 0.0 0.17 12.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK59447.1 - 0.011 15.9 0.2 0.024 14.8 0.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KIK59447.1 - 0.019 15.3 0.2 0.14 12.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK59447.1 - 0.02 15.4 0.1 0.062 13.8 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK59447.1 - 0.027 14.2 0.2 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 TPR repeat MIT PF04212.18 KIK59447.1 - 0.029 14.4 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF4139 PF13598.6 KIK59449.1 - 5.2e-26 91.6 0.0 7.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIK59449.1 - 3.7e-14 52.9 0.1 2e-13 50.6 0.1 2.2 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) TPR_10 PF13374.6 KIK59450.1 - 1.9e-178 574.3 1.8 2.7e-11 43.0 0.0 25.5 24 1 1 25 25 25 24 Tetratricopeptide repeat TPR_12 PF13424.6 KIK59450.1 - 4e-154 501.2 26.5 1.2e-13 51.2 0.2 19.2 4 4 17 22 22 22 22 Tetratricopeptide repeat TPR_1 PF00515.28 KIK59450.1 - 6.5e-49 161.8 44.0 0.00096 18.9 0.1 22.0 23 0 0 23 23 23 13 Tetratricopeptide repeat TPR_2 PF07719.17 KIK59450.1 - 2.4e-43 142.8 39.1 0.0037 17.3 0.0 22.2 23 0 0 23 23 22 9 Tetratricopeptide repeat TPR_7 PF13176.6 KIK59450.1 - 7e-40 132.1 34.4 0.017 15.1 0.0 22.2 24 0 0 24 24 23 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIK59450.1 - 3.5e-38 126.6 42.0 0.012 15.7 0.1 21.2 23 0 0 23 23 22 9 Tetratricopeptide repeat TPR_4 PF07721.14 KIK59450.1 - 3e-25 86.2 0.0 2 9.3 0.0 15.3 17 0 0 17 17 14 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK59450.1 - 2.8e-18 66.3 0.1 2 9.1 0.1 14.8 17 2 1 18 18 15 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK59450.1 - 3.1e-18 65.1 28.3 2.2 9.1 0.1 19.2 23 0 0 23 23 19 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK59450.1 - 6.7e-17 61.5 19.2 0.0057 16.9 0.9 13.0 7 5 5 13 13 13 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIK59450.1 - 2.6e-15 55.8 9.3 14 6.8 0.0 15.8 18 1 1 19 19 14 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK59450.1 - 6.6e-15 55.4 30.2 0.18 12.3 0.3 15.0 9 5 10 19 19 18 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK59450.1 - 1e-14 54.3 18.5 1.6 8.8 0.0 14.5 16 1 1 17 17 16 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 KIK59450.1 - 1.3e-14 54.4 17.3 7.9e-05 22.2 2.0 8.0 2 2 3 7 7 7 4 MalT-like TPR region Rapsyn_N PF10579.9 KIK59450.1 - 3.8e-12 46.1 1.0 0.095 12.8 0.1 9.2 8 3 2 10 10 8 2 Rapsyn N-terminal myristoylation and linker region PPR PF01535.20 KIK59450.1 - 4e-11 42.4 16.9 26 5.3 0.0 16.6 20 0 0 20 20 18 0 PPR repeat TPR_17 PF13431.6 KIK59450.1 - 4.3e-10 39.2 50.3 3.2 8.4 0.1 18.2 22 0 0 22 22 18 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK59450.1 - 6.9e-09 35.2 25.8 0.64 9.8 0.2 14.3 17 0 0 17 17 16 1 TPR repeat TPR_9 PF13371.6 KIK59450.1 - 7.1e-08 32.5 8.7 17 5.7 0.0 10.8 9 2 4 13 13 13 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIK59450.1 - 1.8e-07 31.2 7.5 3.7 7.6 0.1 9.9 5 3 5 10 10 9 1 Putative TPR-like repeat RPN7 PF10602.9 KIK59450.1 - 2.3e-07 30.7 0.3 0.079 12.7 0.0 6.9 5 2 2 7 7 5 1 26S proteasome subunit RPN7 Paf67 PF10255.9 KIK59450.1 - 3.1e-07 29.7 0.0 0.56 9.1 0.0 6.1 5 2 2 7 7 7 1 RNA polymerase I-associated factor PAF67 DUF3856 PF12968.7 KIK59450.1 - 3.4e-06 27.2 6.4 0.8 9.8 0.1 9.2 7 6 3 11 11 9 1 Domain of Unknown Function (DUF3856) SNAP PF14938.6 KIK59450.1 - 0.00017 21.2 0.0 3 7.2 0.0 4.2 5 0 0 5 5 4 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 KIK59450.1 - 0.00021 21.3 8.6 0.35 11.0 0.2 7.3 7 2 2 9 9 6 1 MIT (microtubule interacting and transport) domain PAC3 PF10178.9 KIK59450.1 - 0.00029 20.9 0.1 0.85 9.8 0.0 5.3 5 1 0 5 5 4 1 Proteasome assembly chaperone 3 SPOB_a PF14689.6 KIK59450.1 - 0.0012 18.5 5.7 23 4.8 0.0 9.1 12 0 0 12 12 10 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF4188 PF13826.6 KIK59450.1 - 0.017 15.5 0.1 0.83 10.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) DUF4080 PF13311.6 KIK59450.1 - 0.041 14.1 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) TPR_3 PF07720.12 KIK59450.1 - 0.066 13.2 12.2 36 4.5 0.0 9.0 13 0 0 13 13 11 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KIK59450.1 - 0.1 12.9 29.8 3.6 7.9 0.1 12.2 6 4 8 16 16 15 0 Vacuolar sorting protein 39 domain 1 CBP PF12192.8 KIK59450.1 - 0.21 11.8 0.0 0.95 9.7 0.0 2.1 2 0 0 2 2 1 0 Fungal calcium binding protein DUF4139 PF13598.6 KIK59451.1 - 0.002 17.9 0.1 0.0028 17.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) PRR22 PF15776.5 KIK59451.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Proline-rich protein family 22 DUF4140 PF13600.6 KIK59452.1 - 2.8e-17 62.9 0.0 5.9e-17 61.9 0.0 1.5 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4139 PF13598.6 KIK59452.1 - 5.1e-16 59.0 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) HEPN-like_int PF18867.1 KIK59452.1 - 0.0027 17.6 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 HEPN-like integron domain DUF1776 PF08643.10 KIK59453.1 - 6.7e-19 68.4 0.1 1.1e-18 67.7 0.1 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-C3HC4_3 PF13920.6 KIK59461.1 - 7.7e-12 44.9 9.0 7.7e-12 44.9 9.0 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK59461.1 - 2.3e-08 33.8 8.3 2.3e-08 33.8 8.3 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KIK59461.1 - 1.3e-07 31.6 4.6 1.3e-07 31.6 4.6 2.6 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KIK59461.1 - 3.2e-05 24.2 8.6 3.2e-05 24.2 8.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIK59461.1 - 0.00098 18.9 9.3 0.00098 18.9 9.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KIK59461.1 - 0.0012 19.0 3.2 0.0012 19.0 3.2 3.5 3 0 0 3 3 2 1 FYVE-type zinc finger Rho_N PF07498.12 KIK59461.1 - 0.018 15.0 0.3 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain U79_P34 PF03064.16 KIK59461.1 - 0.094 12.1 6.0 0.16 11.3 6.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF572 PF04502.13 KIK59461.1 - 0.16 11.5 10.4 0.043 13.4 6.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) BUD22 PF09073.10 KIK59461.1 - 2.5 7.4 16.4 0.071 12.5 9.9 1.6 2 0 0 2 2 2 0 BUD22 MCU PF04678.13 KIK59461.1 - 2.6 8.1 4.9 4 7.5 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter zf-RING_UBOX PF13445.6 KIK59461.1 - 9 6.4 15.3 12 6.0 5.2 2.9 2 1 0 2 2 2 0 RING-type zinc-finger ApoB100_C PF12491.8 KIK59463.1 - 0.043 13.8 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal DUF202 PF02656.15 KIK59464.1 - 1 9.8 5.4 0.9 10.0 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF202 PF02656.15 KIK59465.1 - 3.7 8.0 10.3 0.5 10.8 2.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) ATP-synt_ab PF00006.25 KIK59467.1 - 6.4e-63 212.2 0.0 1.1e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIK59467.1 - 8.5e-22 77.5 1.2 8.5e-22 77.5 1.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KIK59467.1 - 0.0056 15.9 0.8 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KIK59467.1 - 0.02 15.3 0.0 0.42 11.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK59467.1 - 0.027 14.9 0.1 0.085 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIK59467.1 - 0.03 14.2 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KIK59467.1 - 0.035 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KIK59467.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KIK59467.1 - 0.071 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KIK59467.1 - 0.089 13.1 0.5 0.31 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK59467.1 - 0.17 12.4 0.2 0.59 10.6 0.2 1.9 1 0 0 1 1 1 0 ABC transporter T3SS_ATPase_C PF18269.1 KIK59467.1 - 0.23 11.3 0.7 0.99 9.3 0.7 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RTA1 PF04479.13 KIK59468.1 - 1.3e-59 201.3 3.4 1.3e-59 201.3 3.4 1.4 2 0 0 2 2 2 1 RTA1 like protein zf-MYND PF01753.18 KIK59469.1 - 5.6e-08 32.7 12.4 9.1e-08 32.1 12.4 1.4 1 0 0 1 1 1 1 MYND finger WASH-7_C PF14746.6 KIK59471.1 - 0.041 13.6 0.0 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF2730 PF10805.8 KIK59472.1 - 0.14 12.2 2.3 4.4 7.5 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF3561 PF12084.8 KIK59473.1 - 0.00053 20.0 3.0 0.00053 20.0 3.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3561) Gaa1 PF04114.14 KIK59473.1 - 0.0026 16.9 0.3 0.0032 16.6 0.3 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component MARVEL PF01284.23 KIK59474.1 - 0.00051 20.1 13.0 0.00069 19.7 13.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Pyr_redox_2 PF07992.14 KIK59475.1 - 1.5e-44 152.4 0.0 2.8e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK59475.1 - 7.7e-13 48.8 0.1 1.1e-08 35.5 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KIK59475.1 - 2.1e-12 45.7 3.9 3.2e-05 23.2 1.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KIK59475.1 - 1.3e-11 44.8 1.9 1e-07 32.3 0.8 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIK59475.1 - 4e-11 41.9 1.1 9.1e-05 21.8 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KIK59475.1 - 6.6e-11 41.2 0.7 1.1e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KIK59475.1 - 0.00027 20.7 0.9 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KIK59475.1 - 0.0052 17.1 0.6 2.3 8.6 0.1 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TrpP PF17099.5 KIK59476.1 - 0.0013 18.5 1.0 0.0019 18.0 1.0 1.1 1 0 0 1 1 1 1 Tryptophan transporter TrpP Myosin_head PF00063.21 KIK59478.1 - 1.4e-238 793.5 0.0 1.7e-238 793.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 KIK59478.1 - 0.0041 17.4 0.2 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.19 KIK59478.1 - 0.0095 15.8 0.3 0.018 14.9 0.3 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KIK59478.1 - 0.046 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KIK59478.1 - 0.053 12.8 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KIK59478.1 - 0.054 14.0 0.4 0.16 12.5 0.2 1.8 1 1 0 1 1 1 0 ABC transporter F-box-like PF12937.7 KIK59479.1 - 8.3e-05 22.4 0.3 0.0005 19.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK59480.1 - 4.4e-06 26.5 0.8 2.9e-05 23.9 0.0 2.9 4 0 0 4 4 4 1 F-box-like F-box-like PF12937.7 KIK59481.1 - 0.00014 21.6 0.5 0.00059 19.7 0.0 2.4 3 0 0 3 3 3 1 F-box-like Mss4 PF04421.13 KIK59482.1 - 7.9e-15 54.8 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Mss4 protein AAA PF00004.29 KIK59483.1 - 7.9e-15 55.5 0.0 2.5e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK59483.1 - 6.1e-07 29.5 0.0 4e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KIK59483.1 - 7.5e-06 25.8 0.0 3.4e-05 23.6 0.0 2.1 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK59483.1 - 0.00019 21.9 0.2 0.0047 17.3 0.0 3.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 KIK59483.1 - 0.00071 19.7 0.1 0.0032 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIK59483.1 - 0.00087 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIK59483.1 - 0.0013 19.1 0.1 0.0045 17.3 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KIK59483.1 - 0.0019 18.5 0.0 0.018 15.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK59483.1 - 0.0031 17.5 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIK59483.1 - 0.0035 17.3 0.1 0.23 11.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.6 KIK59483.1 - 0.014 15.0 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK59483.1 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DNA_pol3_delta PF06144.13 KIK59483.1 - 0.049 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KIK59483.1 - 0.052 12.9 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK59483.1 - 0.054 14.0 0.1 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK59483.1 - 0.073 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KIK59483.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK59483.1 - 0.11 12.9 0.0 0.35 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KIK59483.1 - 0.13 12.7 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK59483.1 - 0.13 11.4 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 KIK59483.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KIK59483.1 - 0.19 11.7 0.0 0.53 10.2 0.0 1.7 2 0 0 2 2 2 0 NTPase F-box-like PF12937.7 KIK59484.1 - 0.00021 21.1 0.2 0.068 13.1 0.0 3.6 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.7 KIK59485.1 - 2.5e-06 27.3 0.0 8.1e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK59486.1 - 7.3e-06 25.8 0.0 2.2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIK59487.1 - 1.3e-50 172.3 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59487.1 - 3e-27 95.6 0.0 3.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK59487.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK59487.1 - 0.0053 16.4 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK59487.1 - 0.0064 16.4 0.2 0.022 14.7 0.0 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK59487.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KIK59487.1 - 0.046 13.3 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase IMUP PF15761.5 KIK59487.1 - 7.6 7.3 7.8 14 6.4 0.4 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein CTP_transf_1 PF01148.20 KIK59488.1 - 0.012 15.4 0.3 0.021 14.6 0.1 1.5 1 1 0 1 1 1 0 Cytidylyltransferase family Orf78 PF06024.12 KIK59488.1 - 0.42 10.9 4.1 0.29 11.5 0.3 2.2 1 1 1 2 2 2 0 Orf78 (ac78) zf-ANAPC11 PF12861.7 KIK59489.1 - 4.7e-39 132.3 9.4 5.9e-39 132.0 9.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK59489.1 - 1.6e-21 76.4 11.1 2.5e-21 75.7 11.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIK59489.1 - 0.00014 22.1 16.7 0.0032 17.8 16.8 2.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK59489.1 - 0.026 14.6 8.5 0.065 13.3 8.5 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 KIK59489.1 - 0.035 13.9 1.7 0.051 13.4 1.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KIK59489.1 - 0.15 12.0 13.6 0.77 9.7 13.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK59489.1 - 0.16 12.0 14.1 23 5.0 15.8 2.9 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KIK59489.1 - 0.72 9.5 19.2 0.47 10.1 14.0 2.7 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KIK59489.1 - 2.7 7.9 17.8 5.4 7.0 14.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK59489.1 - 3.6 7.4 14.0 20 5.0 14.0 2.2 1 1 0 1 1 1 0 RING-like zinc finger Myticin-prepro PF10690.9 KIK59490.1 - 0.97 9.7 9.4 0.13 12.5 0.5 3.2 3 0 0 3 3 3 0 Myticin pre-proprotein from the mussel CLP1_N PF16573.5 KIK59491.1 - 5e-33 113.2 0.0 8.4e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KIK59491.1 - 5.7e-32 111.0 0.0 1.1e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KIK59491.1 - 3.7e-29 101.5 0.0 6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA PF00004.29 KIK59491.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK59491.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK59491.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KIK59491.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family MFS_1 PF07690.16 KIK59492.1 - 4.4e-26 91.6 32.6 1.1e-25 90.4 30.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Cad PF03596.13 KIK59492.1 - 0.095 12.6 2.4 0.34 10.8 0.0 2.6 2 0 0 2 2 2 0 Cadmium resistance transporter VirJ PF06057.11 KIK59492.1 - 0.12 12.3 0.0 4.2 7.2 0.0 2.5 2 1 1 3 3 3 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.16 KIK59493.1 - 1.4e-25 90.0 32.5 4.3e-25 88.4 31.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK59493.1 - 0.0009 18.6 4.7 0.0009 18.6 4.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB F-box-like PF12937.7 KIK59497.1 - 2.3e-06 27.4 1.2 6.3e-06 26.0 1.2 1.8 1 0 0 1 1 1 1 F-box-like Rho_N PF07498.12 KIK59498.1 - 0.063 13.2 0.1 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain XRCC4 PF06632.12 KIK59498.1 - 1.5 7.6 9.9 0.16 10.8 5.1 1.7 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 NOA36 PF06524.12 KIK59498.1 - 2.1 7.6 11.9 3.3 6.9 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KIK59498.1 - 8.5 4.3 7.3 10 4.1 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_Tyr PF07714.17 KIK59499.1 - 3.7e-48 164.1 0.0 4.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK59499.1 - 3.8e-47 160.9 0.0 4.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SAP PF02037.27 KIK59499.1 - 0.0021 17.8 0.3 0.0046 16.7 0.3 1.6 1 0 0 1 1 1 1 SAP domain APH PF01636.23 KIK59499.1 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK59499.1 - 0.016 14.0 0.1 0.038 12.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KIK59499.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIK59499.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Herpes_pp85 PF04637.12 KIK59499.1 - 6.7 5.0 5.9 10 4.4 5.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) F-box-like PF12937.7 KIK59501.1 - 0.0002 21.2 0.1 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK59502.1 - 1.2e-05 25.1 0.8 3.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like BPL_N PF09825.9 KIK59504.1 - 9.3e-29 100.7 0.0 2.3e-15 56.6 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KIK59504.1 - 3.2e-16 59.4 0.0 1.3e-13 51.0 0.0 2.3 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DJ-1_PfpI PF01965.24 KIK59505.1 - 1.5e-13 50.8 0.0 4.5e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK59505.1 - 6.6e-08 32.5 0.0 1.1e-07 31.7 0.0 1.3 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KIK59507.1 - 7.3e-15 55.1 0.0 1.4e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK59507.1 - 4.8e-06 26.4 0.0 8.1e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 ThiJ/PfpI family-like LMWPc PF01451.21 KIK59507.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase DJ-1_PfpI PF01965.24 KIK59508.1 - 1.5e-13 50.8 0.0 3.3e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK59508.1 - 0.0025 17.6 0.0 0.0097 15.6 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like LcrG PF07216.12 KIK59508.1 - 0.18 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 LcrG protein F-box-like PF12937.7 KIK59509.1 - 3.4e-06 26.8 0.7 1.3e-05 24.9 0.7 2.1 1 0 0 1 1 1 1 F-box-like SlyX PF04102.12 KIK59509.1 - 0.034 14.8 0.2 0.092 13.4 0.2 1.7 1 0 0 1 1 1 0 SlyX NPV_P10 PF05531.12 KIK59509.1 - 0.13 12.7 0.4 0.36 11.3 0.4 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CbtB PF09489.10 KIK59510.1 - 0.058 13.5 1.1 0.42 10.7 0.2 2.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF1129 PF06570.11 KIK59510.1 - 7.3 6.0 11.4 4.6 6.7 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 KIK59511.1 - 1.5e-29 103.0 17.6 1.5e-29 103.0 17.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.22 KIK59512.1 - 8.1e-86 288.3 0.0 1e-85 288.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK59512.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AAA PF00004.29 KIK59513.1 - 7.6e-40 136.4 0.2 4.3e-13 49.8 0.0 5.8 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KIK59513.1 - 2.1e-38 132.0 0.0 7.3e-38 130.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK59513.1 - 3.1e-23 82.9 50.4 1e-21 77.9 0.0 7.6 6 2 1 7 7 5 2 AAA domain AAA_lid_6 PF17866.1 KIK59513.1 - 8e-18 64.4 11.6 7.7e-12 45.2 0.2 4.2 3 0 0 3 3 2 2 AAA lid domain AAA_19 PF13245.6 KIK59513.1 - 1.7e-17 64.1 0.0 1.3e-06 28.8 0.0 5.9 5 1 0 5 5 4 4 AAA domain AAA_5 PF07728.14 KIK59513.1 - 4.3e-13 49.5 0.2 0.024 14.6 0.0 5.3 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK59513.1 - 8.4e-13 48.5 21.0 0.0039 16.9 0.0 7.0 6 1 0 7 7 6 4 AAA domain Mg_chelatase PF01078.21 KIK59513.1 - 1.3e-11 44.3 0.0 0.1 11.9 0.0 4.6 4 0 0 4 4 4 4 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIK59513.1 - 6.7e-09 35.7 0.1 0.052 13.3 0.0 4.7 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KIK59513.1 - 1.1e-08 34.9 0.3 0.28 10.9 0.0 5.5 5 0 0 5 5 5 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KIK59513.1 - 2.8e-08 33.8 0.1 0.033 13.9 0.0 5.3 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIK59513.1 - 1.1e-07 32.2 0.1 2.7 8.4 0.0 4.8 4 0 0 4 4 4 2 RNA helicase IstB_IS21 PF01695.17 KIK59513.1 - 1.7e-07 31.2 0.1 0.74 9.5 0.0 4.7 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_24 PF13479.6 KIK59513.1 - 2.3e-07 30.7 1.4 1.6 8.4 0.0 5.4 5 0 0 5 5 5 3 AAA domain Sigma54_activ_2 PF14532.6 KIK59513.1 - 3.9e-06 27.0 0.1 0.05 13.7 0.0 4.7 4 0 0 4 4 4 1 Sigma-54 interaction domain Torsin PF06309.11 KIK59513.1 - 2.2e-05 24.5 0.0 4.3 7.4 0.0 4.2 4 0 0 4 4 4 2 Torsin AAA_7 PF12775.7 KIK59513.1 - 4.2e-05 23.1 1.4 3 7.3 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_22 PF13401.6 KIK59513.1 - 0.00012 22.4 29.7 0.91 9.8 0.1 9.0 9 4 0 11 11 5 4 AAA domain UvrD_C PF13361.6 KIK59513.1 - 0.00012 21.6 5.5 2.1 7.7 0.0 4.3 4 1 0 4 4 3 2 UvrD-like helicase C-terminal domain NTPase_1 PF03266.15 KIK59513.1 - 0.00029 20.8 2.2 4.8 7.1 0.1 4.4 4 0 0 4 4 4 1 NTPase AAA_18 PF13238.6 KIK59513.1 - 0.00037 21.0 17.0 2 9.0 0.1 6.0 5 0 0 5 5 4 2 AAA domain TsaE PF02367.17 KIK59513.1 - 0.0021 18.0 0.6 1.2 9.2 0.0 3.7 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KIK59513.1 - 0.0041 17.5 32.4 0.051 14.0 0.0 6.8 6 1 0 6 6 4 2 AAA ATPase domain AAA_33 PF13671.6 KIK59513.1 - 0.0047 17.1 21.7 0.31 11.2 0.0 6.1 5 0 0 5 5 4 3 AAA domain ResIII PF04851.15 KIK59513.1 - 0.0067 16.4 12.5 0.09 12.8 0.0 5.7 7 0 0 7 7 5 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KIK59513.1 - 0.023 14.4 2.3 68 3.3 0.0 4.3 4 0 0 4 4 4 0 P-loop containing region of AAA domain SRP54 PF00448.22 KIK59513.1 - 0.08 12.6 1.7 11 5.6 0.0 4.3 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_32 PF13654.6 KIK59513.1 - 0.11 11.3 0.0 0.11 11.3 0.0 4.6 4 1 0 4 4 3 0 AAA domain 6PF2K PF01591.18 KIK59513.1 - 0.13 11.6 0.1 4.6 6.5 0.0 2.7 3 0 0 3 3 2 0 6-phosphofructo-2-kinase AAA_25 PF13481.6 KIK59513.1 - 0.47 10.0 11.7 20 4.7 0.0 5.9 6 0 0 6 6 5 0 AAA domain AAA_23 PF13476.6 KIK59513.1 - 4 7.9 0.0 4 7.9 0.0 6.0 6 1 0 6 6 5 0 AAA domain ATPase PF06745.13 KIK59513.1 - 7.2 5.9 14.7 2.2 7.5 0.0 4.9 5 0 0 5 5 4 0 KaiC KH_8 PF17903.1 KIK59515.1 - 1.5e-05 25.0 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KIK59515.1 - 0.0026 17.5 0.8 0.0059 16.4 0.8 1.6 1 0 0 1 1 1 1 KH domain DDE_1 PF03184.19 KIK59516.1 - 9.3e-17 61.2 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 KIK59516.1 - 0.00017 21.2 0.1 0.0004 20.1 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc3_2 PF01498.18 KIK59516.1 - 0.018 15.2 1.5 1.8 8.9 0.1 3.5 2 1 2 4 4 4 0 Transposase HTH_30 PF13556.6 KIK59516.1 - 0.03 14.1 0.2 0.12 12.1 0.1 2.0 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain FbpA PF05833.11 KIK59516.1 - 0.12 11.1 1.3 0.19 10.4 1.3 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ank_4 PF13637.6 KIK59517.1 - 0.00022 21.7 0.0 0.029 15.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK59517.1 - 0.0022 18.6 0.1 0.0073 16.9 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK59517.1 - 0.038 14.3 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3188 PF11384.8 KIK59517.1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Integrin_b_cyt PF08725.11 KIK59521.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Helitron_like_N PF14214.6 KIK59522.1 - 8.8e-10 39.1 0.0 9.2e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KIK59523.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK59524.1 - 7.5e-07 28.6 0.0 7.8e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK59524.1 - 4.1e-06 26.6 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK59524.1 - 2.5e-05 24.7 0.0 2.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK59524.1 - 5.7e-05 23.5 0.0 6.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIK59524.1 - 0.0042 16.4 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KIK59524.1 - 0.0055 17.0 0.0 0.0062 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KIK59524.1 - 0.022 14.0 0.0 0.024 13.9 0.0 1.0 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 KIK59524.1 - 0.075 12.8 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 KIK59524.1 - 0.075 12.8 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK59524.1 - 0.1 12.1 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KIK59524.1 - 0.1 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK59524.1 - 0.14 12.5 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.11 KIK59524.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Torsin SMC_N PF02463.19 KIK59524.1 - 0.17 11.3 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PIF1 PF05970.14 KIK59525.1 - 0.06 12.5 0.5 0.065 12.4 0.5 1.0 1 0 0 1 1 1 0 PIF1-like helicase Glyoxal_oxid_N PF07250.11 KIK59533.1 - 3.4e-35 121.4 0.0 3.9e-34 117.9 0.0 2.6 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK59533.1 - 4.9e-19 68.4 0.0 1.3e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KIK59533.1 - 0.0064 16.5 2.3 2.1 8.4 0.0 4.3 4 1 0 4 4 4 1 Galactose oxidase, central domain BiPBP_C PF06832.12 KIK59533.1 - 0.16 12.0 0.0 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Alph_Pro_TM PF09608.10 KIK59533.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) LDB19 PF13002.7 KIK59534.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Brix PF04427.18 KIK59535.1 - 1.6e-36 126.3 0.1 2e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain KH_1 PF00013.29 KIK59536.1 - 9.3e-44 147.1 8.4 3e-15 55.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIK59536.1 - 2e-16 59.6 6.3 9e-06 25.4 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIK59536.1 - 5.9e-07 29.3 1.3 0.063 13.2 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KIK59536.1 - 8e-05 22.7 5.8 0.3 11.2 0.1 3.6 3 0 0 3 3 3 3 NusA-like KH domain BMC PF00936.19 KIK59536.1 - 0.1 12.6 0.1 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 BMC domain A_deaminase PF00962.22 KIK59537.1 - 3e-30 105.7 0.0 1.5e-27 96.8 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KIK59537.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase family Glyco_transf_22 PF03901.17 KIK59538.1 - 4e-85 286.5 14.8 4.8e-85 286.3 14.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FliD_N PF02465.18 KIK59539.1 - 5.9 7.7 12.6 0.19 12.4 2.0 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Trp_syntA PF00290.20 KIK59540.1 - 3.2e-82 275.3 0.3 4.8e-82 274.7 0.3 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KIK59540.1 - 2.4e-46 158.5 0.3 3.8e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KIK59540.1 - 0.00026 20.5 0.1 0.00075 19.0 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KIK59540.1 - 0.00082 18.8 0.1 0.00082 18.8 0.1 1.7 2 1 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 KIK59540.1 - 0.1 11.9 0.4 0.34 10.2 0.1 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Trp_syntA PF00290.20 KIK59541.1 - 9.3e-86 286.9 0.4 1.4e-85 286.3 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KIK59541.1 - 1.6e-46 159.0 0.3 2.5e-46 158.4 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KIK59541.1 - 0.00017 21.2 0.1 0.00044 19.8 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KIK59541.1 - 0.06 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Asparaginase PF00710.20 KIK59542.1 - 2.1e-56 190.5 0.0 7.3e-56 188.7 0.0 2.0 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KIK59542.1 - 9.7e-32 109.6 0.0 2e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 KIK59542.1 - 6.5e-18 64.9 0.0 5.5e-09 36.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK59542.1 - 1.8e-16 60.4 0.1 1.7e-15 57.3 0.2 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK59542.1 - 1.9e-12 46.2 0.5 0.0027 18.0 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KIK59542.1 - 7.3e-12 45.2 3.6 1.4e-05 25.3 0.3 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK59542.1 - 3.2e-11 43.2 1.2 5.2e-08 33.0 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) IF-2B PF01008.17 KIK59543.1 - 1.3e-63 214.8 0.0 1.6e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family QSOX_Trx1 PF18108.1 KIK59543.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 QSOX Trx-like domain GTP_EFTU PF00009.27 KIK59544.1 - 8.4e-51 172.3 0.2 1.3e-50 171.7 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KIK59544.1 - 4.5e-44 149.0 0.1 1.1e-43 147.8 0.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KIK59544.1 - 1.8e-19 69.6 0.0 3.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK59544.1 - 5.6e-10 39.5 0.3 1.3e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK59544.1 - 5.3e-06 26.5 0.1 1.2e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KIK59544.1 - 1.8e-05 24.7 0.0 4.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KIK59544.1 - 0.0003 20.6 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KIK59544.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KIK59544.1 - 0.013 14.9 0.4 0.062 12.7 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 KIK59546.1 - 2.2e-08 34.3 0.0 3.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KIK59546.1 - 4.5e-06 26.5 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 KIK59546.1 - 8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU PF00009.27 KIK59547.1 - 4.6e-08 32.8 0.0 6.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SIL1 PF16782.5 KIK59547.1 - 0.087 12.0 0.0 0.094 11.9 0.0 1.0 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 cwf18 PF08315.12 KIK59549.1 - 5.3e-30 104.8 14.7 5.3e-30 104.8 14.7 1.8 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor Pyridox_ox_2 PF12900.7 KIK59549.1 - 0.022 14.7 0.4 0.04 13.9 0.4 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SIR4_SID PF16991.5 KIK59549.1 - 0.047 13.8 0.7 0.062 13.4 0.7 1.3 1 0 0 1 1 1 0 Sir4 SID domain Peptidase_C107 PF17222.3 KIK59549.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 S36_mt PF10937.8 KIK59550.1 - 2.1e-12 48.7 2.1 2.4e-06 29.1 1.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial Proteasome PF00227.26 KIK59551.1 - 5.2e-47 159.8 0.1 1.7e-46 158.1 0.1 1.7 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK59551.1 - 1.1e-14 53.7 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_1 PF04997.12 KIK59554.1 - 7e-88 295.0 0.0 1.1e-87 294.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIK59554.1 - 4e-81 272.3 0.1 6.3e-81 271.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIK59554.1 - 2.1e-71 239.5 0.0 5.2e-71 238.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIK59554.1 - 1.3e-39 135.7 0.1 1.2e-38 132.5 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KIK59554.1 - 7.2e-31 106.3 0.0 1.6e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 IRF PF00605.17 KIK59554.1 - 0.07 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Prominin PF05478.11 KIK59555.1 - 0.0043 15.1 0.7 0.0056 14.7 0.7 1.1 1 0 0 1 1 1 1 Prominin GIT_CC PF16559.5 KIK59555.1 - 0.013 15.3 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Imm49 PF15575.6 KIK59555.1 - 0.032 14.0 0.3 0.071 12.9 0.3 1.5 1 0 0 1 1 1 0 Immunity protein 49 Sigma70_ner PF04546.13 KIK59555.1 - 0.4 10.5 11.4 17 5.2 0.0 2.5 2 1 0 2 2 2 0 Sigma-70, non-essential region TMPIT PF07851.13 KIK59555.1 - 0.44 9.7 2.3 8.3 5.6 0.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein Baculo_PEP_C PF04513.12 KIK59555.1 - 0.65 10.0 2.9 1.8 8.6 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus G-gamma PF00631.22 KIK59556.1 - 2.7e-23 81.8 0.0 2.9e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.22 KIK59559.1 - 5.9e-22 77.4 0.1 6.6e-22 77.3 0.1 1.0 1 0 0 1 1 1 1 GGL domain Thioredoxin_2 PF13098.6 KIK59561.1 - 0.0058 17.1 0.0 0.0065 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KIK59561.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Cu_amine_oxid PF01179.20 KIK59562.1 - 9.8e-124 413.4 0.1 1.4e-123 412.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KIK59562.1 - 3.7e-06 26.6 0.2 1e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Peptidase_A4 PF01828.17 KIK59563.1 - 4.5e-68 228.8 17.9 5.2e-68 228.6 17.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family Maff2 PF12750.7 KIK59564.1 - 0.039 13.8 0.6 0.079 12.8 0.6 1.5 1 0 0 1 1 1 0 Maff2 family Cu_bind_like PF02298.17 KIK59564.1 - 0.13 12.3 0.5 0.4 10.7 0.5 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain F-box-like PF12937.7 KIK59566.1 - 4.1e-06 26.6 0.6 1.3e-05 25.0 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK59567.1 - 1.2e-06 28.2 0.1 4.6e-06 26.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like Myotub-related PF06602.14 KIK59568.1 - 2.8e-149 496.9 0.3 3.4e-149 496.6 0.3 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KIK59568.1 - 0.00033 20.5 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain S-AdoMet_synt_C PF02773.16 KIK59569.1 - 5.1e-67 224.1 0.3 2.1e-66 222.1 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KIK59569.1 - 3.5e-45 153.1 0.0 6.2e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KIK59569.1 - 1.7e-44 150.5 1.0 2.3e-44 150.1 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KIK59569.1 - 0.0026 16.6 0.8 0.16 10.8 0.2 2.2 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) His_Phos_1 PF00300.22 KIK59570.1 - 1.4e-26 93.4 1.3 3.3e-25 88.9 1.3 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 KIK59572.1 - 0.00036 20.4 0.1 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK59573.1 - 1.5e-05 24.8 0.0 4.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK59574.1 - 2.1e-06 27.5 0.0 5.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like UQ_con PF00179.26 KIK59575.1 - 9.6e-15 54.5 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK59575.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain CLN6 PF15156.6 KIK59576.1 - 0.024 14.0 0.2 0.027 13.8 0.2 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 F-box-like PF12937.7 KIK59577.1 - 1.2e-06 28.3 0.0 5.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like Hit1_C PF18268.1 KIK59577.1 - 0.067 13.3 0.1 14 6.0 0.1 2.4 2 0 0 2 2 2 0 Hit1 C-terminal MFS_1 PF07690.16 KIK59579.1 - 8.8e-25 87.4 31.4 1.3e-24 86.9 31.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.7 KIK59580.1 - 0.0012 18.7 0.3 0.0066 16.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like SRPRB PF09439.10 KIK59581.1 - 3.5e-16 59.1 0.0 4.4e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK59581.1 - 3.5e-06 27.1 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK59581.1 - 8.5e-05 22.1 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK59581.1 - 0.0015 18.1 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KIK59581.1 - 0.0043 16.6 0.0 0.014 14.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KIK59581.1 - 0.0059 16.0 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KIK59581.1 - 0.075 12.5 0.0 15 5.0 0.0 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KIK59581.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 KIK59583.1 - 9.6e-25 87.1 0.0 1.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KIK59583.1 - 2.8e-11 43.2 0.0 3.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK59583.1 - 1.8e-07 30.7 0.0 3.5e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK59583.1 - 3.6e-06 27.1 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KIK59583.1 - 0.00073 19.1 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region GTP_EFTU PF00009.27 KIK59583.1 - 0.0019 17.8 0.0 0.26 10.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KIK59583.1 - 0.0023 17.6 0.7 0.0092 15.7 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 KIK59583.1 - 0.0083 16.3 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIK59583.1 - 0.012 14.8 0.0 3.3 6.8 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 KIK59583.1 - 0.018 15.6 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK59583.1 - 0.041 13.0 0.0 0.081 12.0 0.0 1.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cation_ATPase_C PF00689.21 KIK59583.1 - 0.052 13.3 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus FeoB_N PF02421.18 KIK59583.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PP2C PF00481.21 KIK59583.1 - 0.094 12.3 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C AAA_16 PF13191.6 KIK59583.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PPV_E1_C PF00519.17 KIK59583.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase GST_C_6 PF17171.4 KIK59584.1 - 7.6e-15 54.5 0.0 1.7e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 KIK59584.1 - 0.0025 18.0 0.2 0.0062 16.8 0.1 1.7 1 1 1 2 2 2 1 SAM35, subunit of SAM coomplex GST_N_4 PF17172.4 KIK59584.1 - 0.011 16.4 0.0 1.4 9.7 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KIK59584.1 - 0.086 13.1 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 KIK59584.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TRAM_LAG1_CLN8 PF03798.16 KIK59585.1 - 4.4e-31 108.2 17.5 4.4e-31 108.2 17.5 1.5 2 0 0 2 2 2 1 TLC domain Ndc1_Nup PF09531.10 KIK59585.1 - 6.5 5.3 11.5 0.75 8.4 7.3 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup His_Phos_1 PF00300.22 KIK59586.1 - 7.1e-19 68.3 0.3 6e-18 65.2 0.0 2.1 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) GATase_6 PF13522.6 KIK59588.1 - 5.9e-12 45.9 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIK59588.1 - 5.4e-10 39.3 0.0 9.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KIK59588.1 - 1.3e-09 37.8 0.1 2.1e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KIK59588.1 - 1.7e-05 23.9 0.0 3.8e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Gti1_Pac2 PF09729.9 KIK59589.1 - 5.3e-30 104.9 0.1 4.8e-28 98.5 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Elongin_A PF06881.11 KIK59590.1 - 2.1e-19 70.0 0.0 6e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.32 KIK59591.1 - 9.8e-32 108.5 15.5 3.3e-07 30.9 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59591.1 - 8.4e-11 42.0 3.5 0.0014 18.9 0.1 4.4 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KIK59591.1 - 5.8e-05 22.2 0.8 0.53 9.2 0.1 4.0 4 0 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 KIK59591.1 - 0.027 13.6 0.3 0.081 12.0 0.1 1.7 2 0 0 2 2 2 0 Coatomer WD associated region DUF3095 PF11294.8 KIK59592.1 - 0.034 13.2 0.3 0.05 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) PLATZ PF04640.14 KIK59592.1 - 0.056 14.1 1.3 0.12 13.1 1.3 1.6 1 0 0 1 1 1 0 PLATZ transcription factor Ecl1 PF12855.7 KIK59592.1 - 0.1 13.7 53.5 1.8e+04 -6.7 53.5 3.3 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins Vps54 PF07928.12 KIK59593.1 - 1.2e-51 174.6 3.5 5.6e-51 172.5 3.5 2.2 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 KIK59593.1 - 2.6e-06 27.4 0.7 5e-06 26.5 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KIK59593.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex ATG16 PF08614.11 KIK59593.1 - 0.047 13.9 3.0 7.8 6.7 0.6 2.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) COG5 PF10392.9 KIK59593.1 - 0.14 12.4 2.0 0.26 11.5 0.1 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Utp21 PF04192.12 KIK59596.1 - 5.6e-58 196.2 0.7 9.4e-58 195.5 0.7 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KIK59596.1 - 6.3e-16 58.5 14.3 0.014 16.3 0.0 9.9 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59596.1 - 2e-15 56.9 0.0 0.0078 16.5 0.0 7.3 2 2 6 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KIK59596.1 - 0.00011 22.0 3.3 0.039 13.7 0.5 3.8 3 1 0 4 4 4 1 TUP1-like enhancer of split PQQ_2 PF13360.6 KIK59596.1 - 0.0013 18.3 0.3 0.0083 15.7 0.1 2.2 2 0 0 2 2 2 1 PQQ-like domain HRI1 PF16815.5 KIK59597.1 - 6e-39 134.1 2.0 7.4e-39 133.8 2.0 1.1 1 0 0 1 1 1 1 Protein HRI1 Skp1 PF01466.19 KIK59602.1 - 2.7e-29 101.0 0.5 4.7e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK59602.1 - 8.6e-25 86.7 1.4 1.3e-24 86.1 0.1 2.0 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KIK59602.1 - 0.00014 22.0 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_L27 PF01016.19 KIK59603.1 - 1.4e-33 114.7 1.3 1.9e-33 114.3 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3074 PF11274.8 KIK59604.1 - 2e-43 148.6 0.6 2.5e-43 148.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 KIK59604.1 - 0.00047 19.6 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3067 PF11267.8 KIK59604.1 - 0.014 15.9 0.2 8.9 7.0 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3067) YyzF PF14116.6 KIK59604.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 YyzF-like protein Gln-synt_C PF00120.24 KIK59605.1 - 2.5e-75 253.6 0.0 5.6e-75 252.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain WD40 PF00400.32 KIK59606.1 - 1e-06 29.4 0.1 0.13 13.2 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KIK59606.1 - 0.00092 19.6 0.0 2 9.0 0.0 3.6 3 0 0 3 3 3 1 PQQ-like domain Tim17 PF02466.19 KIK59607.1 - 0.11 12.9 0.8 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 KIK59607.1 - 0.71 10.0 6.7 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide mRNA_cap_enzyme PF01331.19 KIK59608.1 - 1.8e-49 168.2 0.0 2.4e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KIK59608.1 - 1e-31 109.8 0.0 1.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KIK59608.1 - 2.2e-12 47.0 0.0 3e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Cep57_MT_bd PF06657.13 KIK59609.1 - 7.6e-24 84.0 1.5 7.6e-24 84.0 1.5 4.5 3 1 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KIK59609.1 - 3.9e-05 23.6 3.2 3.9e-05 23.6 3.2 4.0 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Herpes_UL6 PF01763.16 KIK59609.1 - 0.27 9.7 2.3 0.44 9.0 2.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like TMF_TATA_bd PF12325.8 KIK59609.1 - 0.5 10.6 20.0 0.69 10.2 1.9 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding MCD_N PF17408.2 KIK59609.1 - 0.73 10.0 4.5 0.76 9.9 0.5 2.5 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Astro_capsid_p PF12226.8 KIK59609.1 - 1.6 7.8 12.0 4 6.5 12.0 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HeLo PF14479.6 KIK59609.1 - 1.6 8.5 6.7 2 8.2 5.1 2.0 2 0 0 2 2 2 0 Prion-inhibition and propagation CENP-O PF09496.10 KIK59609.1 - 1.9 8.4 7.6 1.1 9.2 0.3 2.6 2 1 0 2 2 2 0 Cenp-O kinetochore centromere component CLZ PF16526.5 KIK59609.1 - 5.2 7.5 10.7 0.72 10.3 0.5 4.0 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Glyco_hydro_10 PF00331.20 KIK59612.1 - 2.4e-106 355.4 0.1 3e-106 355.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KIK59612.1 - 1.6e-14 53.5 10.1 1.6e-14 53.5 10.1 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Sulfatase PF00884.23 KIK59613.1 - 2.5e-76 257.0 0.0 3.1e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KIK59613.1 - 0.0015 19.3 0.1 0.03 15.0 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KIK59613.1 - 0.0027 17.3 0.0 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KIK59613.1 - 0.0076 16.1 0.1 0.021 14.8 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 KIK59613.1 - 0.0088 16.3 0.0 0.027 14.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KIK59613.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 KIK59614.1 - 4.9e-91 305.9 19.2 5.6e-91 305.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK59614.1 - 2.1e-22 79.5 26.0 2.7e-16 59.5 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK59614.1 - 7e-06 24.7 2.4 7e-06 24.7 2.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 KIK59615.1 - 9.4e-05 22.2 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like ASFV_L11L PF05293.11 KIK59615.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein F-box-like PF12937.7 KIK59616.1 - 0.0022 17.9 0.1 0.0081 16.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like Ricin_B_lectin PF00652.22 KIK59617.1 - 3.4e-27 95.2 3.5 0.0003 21.0 0.0 5.9 3 3 4 7 7 7 7 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIK59617.1 - 2.9e-15 56.7 12.1 0.0025 18.5 0.0 6.8 6 0 0 6 6 6 5 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 KIK59617.1 - 0.0032 17.5 0.0 12 5.9 0.0 3.5 3 0 0 3 3 3 2 FIST C domain SH3_19 PF18597.1 KIK59617.1 - 0.11 12.3 0.0 29 4.6 0.0 3.1 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain Lum_binding PF00677.17 KIK59617.1 - 0.15 12.1 14.0 4.1 7.4 0.2 5.5 4 2 2 6 6 6 0 Lumazine binding domain DUF4813 PF16072.5 KIK59617.1 - 4.5 6.9 56.2 0.47 10.1 21.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4813) MARVEL PF01284.23 KIK59620.1 - 0.058 13.4 12.6 0.77 9.8 0.5 2.2 2 0 0 2 2 2 0 Membrane-associating domain Adeno_E3_CR2 PF02439.15 KIK59620.1 - 0.23 11.3 2.4 0.54 10.0 2.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DRIM PF07539.12 KIK59622.1 - 2.4e-180 600.9 6.8 2.4e-180 600.9 6.8 4.2 4 1 0 4 4 4 1 Down-regulated in metastasis ParcG PF10274.9 KIK59622.1 - 0.026 14.6 1.7 1.2 9.2 0.0 3.6 3 0 0 3 3 3 0 Parkin co-regulated protein MMS19_N PF14500.6 KIK59622.1 - 0.029 14.0 8.6 0.38 10.3 0.2 5.5 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 KIK59622.1 - 0.18 12.1 1.2 34 5.1 0.2 5.4 6 0 0 6 6 6 0 HEAT repeat DUF3361 PF11841.8 KIK59622.1 - 0.3 11.0 6.7 1.9 8.4 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) GGACT PF06094.12 KIK59623.1 - 2.6e-08 34.5 0.1 3.3e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KIK59623.1 - 4.8e-06 26.9 0.1 9e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 AIG2-like family STN1_2 PF09170.10 KIK59623.1 - 0.043 14.0 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Imm17 PF15562.6 KIK59623.1 - 0.069 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 17 DUF5504 PF17608.2 KIK59624.1 - 0.35 11.0 5.0 0.13 12.3 1.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5504) Proteasome PF00227.26 KIK59625.1 - 2.5e-49 167.3 0.1 3.1e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit AA_permease PF00324.21 KIK59626.1 - 1.1e-108 364.0 35.0 1.3e-108 363.7 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK59626.1 - 5.7e-15 55.1 43.1 7.6e-15 54.7 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.21 KIK59627.1 - 8.2e-40 136.8 0.3 2.7e-35 122.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family RBD PF02196.15 KIK59627.1 - 0.046 13.8 0.0 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 Raf-like Ras-binding domain LIM PF00412.22 KIK59628.1 - 2e-17 63.1 20.1 2.3e-11 43.8 5.4 3.9 4 0 0 4 4 4 2 LIM domain CxC6 PF18721.1 KIK59628.1 - 6.5 7.1 7.9 6.2 7.2 5.5 2.2 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases zf_UBZ PF18439.1 KIK59629.1 - 0.17 11.5 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Syja_N PF02383.18 KIK59630.1 - 3.3e-93 312.5 0.0 5.7e-93 311.7 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KIK59630.1 - 2.2e-33 114.4 0.0 1.4e-32 111.8 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase Pkinase PF00069.25 KIK59633.1 - 1.9e-14 53.6 0.0 2.3e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59633.1 - 5.3e-06 25.9 0.0 5.6e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase pPIWI_RE_Z PF18155.1 KIK59634.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 pPIWI RE three-gene island domain Z DMAP_binding PF06464.11 KIK59635.1 - 0.14 13.0 0.1 0.22 12.3 0.1 1.2 1 0 0 1 1 1 0 DMAP1-binding Domain DUF4906 PF16249.5 KIK59636.1 - 0.095 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) Collagen PF01391.18 KIK59638.1 - 6.9e-09 35.3 25.3 6.9e-09 35.3 25.3 2.1 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) RRM_1 PF00076.22 KIK59639.1 - 1.3e-25 89.0 0.0 1.4e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KIK59639.1 - 2.5e-21 74.1 0.0 7.5e-05 22.2 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KIK59639.1 - 1.5e-05 24.7 0.0 0.06 13.2 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 KIK59639.1 - 0.099 12.1 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif CDC50 PF03381.15 KIK59640.1 - 2.9e-92 309.2 0.1 3.9e-92 308.7 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ECF_trnsprt PF12822.7 KIK59640.1 - 0.53 10.4 3.5 6.5 6.8 0.6 2.3 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Gar1 PF04410.14 KIK59641.1 - 4.7e-37 127.1 0.0 5.9e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 KIK59642.1 - 9.6e-54 181.4 0.0 1.3e-42 145.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK59642.1 - 6.7e-09 35.4 4.4 3.4e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KIK59642.1 - 3.3e-07 30.8 0.4 0.006 17.0 0.0 4.2 5 0 0 5 5 4 1 AAA ATPase domain AAA_5 PF07728.14 KIK59642.1 - 7e-06 26.1 0.0 0.011 15.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK59642.1 - 1.7e-05 24.6 0.0 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIK59642.1 - 0.00012 22.6 0.0 0.024 15.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KIK59642.1 - 0.00088 18.6 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Vps4_C PF09336.10 KIK59642.1 - 0.00088 19.2 0.0 0.076 13.0 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KIK59642.1 - 0.0013 19.0 0.1 0.011 16.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KIK59642.1 - 0.0024 18.0 0.0 0.0092 16.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KIK59642.1 - 0.0029 17.6 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KIK59642.1 - 0.0044 16.7 0.0 0.98 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 KIK59642.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF815 PF05673.13 KIK59642.1 - 0.0089 15.2 0.0 0.91 8.6 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK59642.1 - 0.012 16.0 0.0 0.069 13.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KIK59642.1 - 0.013 15.5 0.1 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KIK59642.1 - 0.018 14.8 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KIK59642.1 - 0.022 14.3 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIK59642.1 - 0.029 13.8 0.3 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIK59642.1 - 0.039 13.5 1.6 0.1 12.2 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 KIK59642.1 - 0.049 13.4 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIK59642.1 - 0.051 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KIK59642.1 - 0.079 12.8 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIK59642.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KIK59642.1 - 0.18 12.1 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Copper-bind PF00127.20 KIK59644.1 - 0.00024 21.5 0.1 0.00048 20.5 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Hid1 PF12722.7 KIK59645.1 - 2.6e-181 604.8 0.0 3.1e-181 604.5 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KIK59645.1 - 5.1e-91 306.0 0.0 6.4e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DeoRC PF00455.22 KIK59645.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain AMP-binding PF00501.28 KIK59646.1 - 3e-78 263.3 0.0 3.9e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK59646.1 - 0.00026 21.9 0.0 0.0006 20.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 KIK59646.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 FeoA domain TPT PF03151.16 KIK59647.1 - 7.3e-09 35.4 16.8 1.1e-08 34.8 16.8 1.2 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF1270 PF06900.11 KIK59647.1 - 0.41 11.1 0.1 0.41 11.1 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1270) Glyco_transf_15 PF01793.16 KIK59648.1 - 5.6e-58 196.7 5.1 1.7e-36 126.1 0.1 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 KIK59649.1 - 7.7e-13 48.7 8.9 0.024 15.5 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat MAGE_N PF12440.8 KIK59649.1 - 0.0036 17.9 1.8 3.5 8.4 0.1 2.5 2 0 0 2 2 2 2 Melanoma associated antigen family N terminal Nup160 PF11715.8 KIK59649.1 - 0.04 12.6 0.5 0.15 10.7 0.3 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Y2_Tnp PF04986.13 KIK59649.1 - 0.47 10.5 1.0 32 4.5 0.0 2.9 3 0 0 3 3 3 0 Putative transposase Proteasome PF00227.26 KIK59650.1 - 1.2e-28 99.9 0.1 1.4e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DDE_Tnp_IS66 PF03050.14 KIK59650.1 - 0.18 11.2 0.0 0.38 10.2 0.0 1.4 2 0 0 2 2 2 0 Transposase IS66 family Acetyltransf_3 PF13302.7 KIK59651.1 - 4.5e-11 43.6 0.0 5.6e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK59651.1 - 7e-05 23.0 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family L31 PF09784.9 KIK59652.1 - 1.5e-41 140.9 0.0 1.7e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PRP21_like_P PF12230.8 KIK59653.1 - 2.2e-48 165.0 15.8 2.2e-48 165.0 15.8 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KIK59653.1 - 3.9e-33 113.2 0.7 2e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 KIK59653.1 - 1.1e-08 34.7 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 KIK59653.1 - 0.00017 21.1 0.2 0.00036 20.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF2407 PF10302.9 KIK59653.1 - 0.0025 18.3 0.1 0.0025 18.3 0.1 2.7 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KIK59653.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like E7 PF00527.18 KIK59653.1 - 0.63 10.3 8.5 1.9 8.7 0.2 3.0 3 0 0 3 3 3 0 E7 protein, Early protein UQ_con PF00179.26 KIK59655.1 - 4.8e-19 68.4 0.0 7.8e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK59655.1 - 0.029 14.6 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain Rubredoxin PF00301.20 KIK59655.1 - 0.53 10.4 0.1 0.53 10.4 0.1 2.0 3 0 0 3 3 3 0 Rubredoxin NYN PF01936.18 KIK59656.1 - 4e-22 79.3 0.0 6.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 NYN domain CHCH PF06747.13 KIK59657.1 - 2.2e-06 27.6 0.5 2.8e-06 27.3 0.5 1.1 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KIK59657.1 - 0.0029 17.6 0.6 0.0054 16.7 0.6 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CDH-cyt PF16010.5 KIK59658.1 - 3.1e-11 43.3 0.0 5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KIK59658.1 - 8.9e-11 42.1 4.2 1.6e-10 41.2 4.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KIK59658.1 - 7.4e-10 39.1 0.0 1.5e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 KIK59658.1 - 0.0038 17.4 5.8 0.0038 17.4 5.8 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF4079) BIV_Env PF05858.12 KIK59658.1 - 0.1 10.7 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) CBP_BcsF PF11120.8 KIK59658.1 - 1.1 9.5 4.7 22 5.3 0.1 3.1 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF Pet100 PF09803.9 KIK59659.1 - 4e-27 94.5 0.2 5.7e-27 94.0 0.2 1.2 1 0 0 1 1 1 1 Pet100 Cwf_Cwc_15 PF04889.12 KIK59659.1 - 0.16 11.7 6.1 0.19 11.4 6.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PALP PF00291.25 KIK59660.1 - 2.1e-48 165.2 0.1 2.5e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RolB_RolC PF02027.17 KIK59660.1 - 0.12 12.1 0.0 0.54 9.9 0.0 2.0 3 0 0 3 3 3 0 RolB/RolC glucosidase family Glyco_hydro_31 PF01055.26 KIK59661.1 - 7e-120 401.2 1.6 8.8e-120 400.8 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIK59661.1 - 9.5e-17 61.1 0.1 2.3e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Cmc1 PF08583.10 KIK59662.1 - 4.6e-14 52.2 6.2 5.7e-14 51.9 6.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KIK59662.1 - 0.099 12.9 1.5 0.11 12.7 1.5 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 KIK59662.1 - 1.4 9.1 5.9 1.1 9.4 0.3 2.5 3 0 0 3 3 3 0 CHCH domain Transketolase_N PF00456.21 KIK59663.1 - 1.6e-145 484.3 0.0 2.1e-145 483.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KIK59663.1 - 5.1e-41 140.3 0.0 8.2e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIK59663.1 - 8.9e-12 45.0 0.0 1.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIK59663.1 - 0.00055 19.2 0.0 0.00095 18.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KIK59663.1 - 0.029 13.3 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Terpene_synth PF01397.21 KIK59663.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain UCR_14kD PF02271.16 KIK59664.1 - 1.9e-40 136.9 1.1 2.2e-40 136.7 1.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.19 KIK59665.1 - 1.8e-54 183.4 0.0 2e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Transcrip_reg PF01709.20 KIK59666.1 - 1.4e-62 211.2 0.4 1.6e-62 211.0 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator Spore_III_AB PF09548.10 KIK59666.1 - 0.14 12.2 0.2 0.35 11.0 0.0 1.8 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RRM_1 PF00076.22 KIK59668.1 - 2.2e-28 97.9 0.0 3.5e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK59668.1 - 5e-10 39.4 0.1 0.00027 21.0 0.0 3.0 3 1 0 3 3 3 2 RNA recognition motif OB_RNB PF08206.11 KIK59668.1 - 0.13 12.0 0.3 1.3 8.8 0.1 2.5 1 1 1 2 2 2 0 Ribonuclease B OB domain Sulfate_transp PF00916.20 KIK59669.1 - 1e-116 389.8 14.5 1.3e-116 389.5 14.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIK59669.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KIK59669.1 - 0.00097 19.5 12.8 0.0035 17.7 2.5 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KIK59669.1 - 0.012 15.9 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 STAS domain WD40 PF00400.32 KIK59670.1 - 1.7e-25 88.8 7.7 2.5e-09 37.6 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK59670.1 - 9.9e-06 25.8 0.0 0.037 14.3 0.0 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK59670.1 - 0.0019 17.2 0.0 0.037 13.0 0.0 2.9 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FA_hydroxylase PF04116.13 KIK59671.1 - 5.1e-25 88.4 20.7 5.1e-25 88.4 20.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PIN_4 PF13638.6 KIK59672.1 - 1.1e-17 64.5 0.1 1.1e-17 64.5 0.1 1.9 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 KIK59672.1 - 3.1e-12 46.6 0.0 1.2e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF2721 PF11026.8 KIK59672.1 - 0.21 11.5 0.7 11 5.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RRN3 PF05327.11 KIK59672.1 - 1.2 7.6 4.0 6.1 5.3 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DBR1 PF05011.13 KIK59673.1 - 1.7e-40 138.7 0.0 3.6e-40 137.6 0.0 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KIK59673.1 - 1.1e-12 48.8 0.0 1.9e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK59673.1 - 0.079 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pyridoxal_deC PF00282.19 KIK59674.1 - 4.7e-63 213.1 0.0 7.1e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIK59674.1 - 2.8e-05 23.3 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V RNase_T PF00929.24 KIK59676.1 - 4.3e-15 56.7 0.0 3.1e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KIK59676.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like CMS1 PF14617.6 KIK59677.1 - 1.1e-76 257.5 0.8 1.4e-76 257.2 0.8 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit YqfQ PF14181.6 KIK59677.1 - 1 9.5 5.0 1.8 8.8 5.0 1.3 1 0 0 1 1 1 0 YqfQ-like protein AAA PF00004.29 KIK59678.1 - 2.4e-15 57.1 0.0 7.5e-15 55.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIK59678.1 - 3.3e-12 46.5 0.0 2.8e-10 40.2 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KIK59678.1 - 6.6e-12 45.7 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 KIK59678.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KIK59678.1 - 5.8e-06 26.6 0.0 4e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KIK59678.1 - 1.6e-05 25.1 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KIK59678.1 - 3e-05 24.5 0.1 0.00026 21.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KIK59678.1 - 3.5e-05 23.7 0.0 9.1e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK59678.1 - 0.00028 20.7 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KIK59678.1 - 0.0003 20.6 0.0 0.00092 19.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK59678.1 - 0.00038 20.5 0.0 0.002 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK59678.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIK59678.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK59678.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 KIK59678.1 - 0.0043 17.1 0.0 0.04 13.9 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK59678.1 - 0.0052 17.1 0.0 0.046 14.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK59678.1 - 0.0052 16.2 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KIK59678.1 - 0.016 14.5 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KIK59678.1 - 0.018 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KIK59678.1 - 0.046 13.5 0.2 0.62 9.8 0.0 2.5 2 1 0 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.13 KIK59678.1 - 0.047 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KIK59678.1 - 0.075 12.5 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 KIK59678.1 - 0.084 13.4 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK59678.1 - 0.092 13.3 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KIK59678.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KIK59678.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DNA_pol3_delta PF06144.13 KIK59678.1 - 0.21 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit CAF1A PF12253.8 KIK59679.1 - 8.8e-22 77.1 4.1 2.3e-21 75.7 4.1 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Codanin-1_C PF15296.6 KIK59679.1 - 0.17 12.0 3.6 0.56 10.3 3.6 1.9 1 0 0 1 1 1 0 Codanin-1 C-terminus FAA_hydrolase PF01557.18 KIK59680.1 - 4.8e-56 189.9 0.0 5.7e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Con-6 PF10346.9 KIK59681.1 - 1.2e-44 150.0 9.5 1.3e-14 53.9 1.5 3.1 3 0 0 3 3 3 3 Conidiation protein 6 Sigma70_r1_1 PF03979.14 KIK59681.1 - 0.00015 21.8 0.0 0.38 10.8 0.0 2.2 2 0 0 2 2 2 2 Sigma-70 factor, region 1.1 PASTA PF03793.19 KIK59681.1 - 0.00024 20.9 0.5 0.099 12.5 0.1 2.4 2 1 0 2 2 2 2 PASTA domain SpoIIIAH PF12685.7 KIK59681.1 - 0.01 15.7 6.2 0.043 13.7 0.5 2.7 1 1 1 2 2 2 0 SpoIIIAH-like protein Pyr_redox_2 PF07992.14 KIK59681.1 - 0.024 13.9 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EPSP_synthase PF00275.20 KIK59681.1 - 0.026 13.2 0.1 0.041 12.6 0.1 1.4 1 1 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF1539 PF07560.11 KIK59681.1 - 0.051 13.7 0.2 6.2 6.9 0.0 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) GA-like PF17573.2 KIK59681.1 - 0.12 12.3 2.3 7 6.7 0.2 2.6 3 0 0 3 3 3 0 GA-like domain Arm-DNA-bind_4 PF14657.6 KIK59681.1 - 0.22 11.3 0.5 21 4.9 0.0 2.6 2 0 0 2 2 2 0 Arm DNA-binding domain Linker_histone PF00538.19 KIK59682.1 - 9e-07 29.2 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family Rtt106 PF08512.12 KIK59683.1 - 0.045 14.2 0.3 0.13 12.7 0.1 1.8 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Chitin_synth_1 PF01644.17 KIK59686.1 - 4e-77 257.8 0.1 5.7e-77 257.3 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK59686.1 - 3.9e-28 97.2 0.0 1.3e-27 95.5 0.0 2.0 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK59686.1 - 8.2e-24 84.1 1.6 2.4e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK59686.1 - 0.0026 17.7 13.9 0.066 13.1 13.9 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 2Fe-2S_thioredx PF01257.19 KIK59688.1 - 3.9e-57 192.2 0.0 4.6e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.21 KIK59689.1 - 1.4e-42 146.1 0.2 2.3e-41 142.1 0.2 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RNase_P_p30 PF01876.16 KIK59690.1 - 3.1e-37 128.1 0.0 4.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Ndc80_HEC PF03801.13 KIK59692.1 - 3.3e-30 104.7 0.0 6.7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KIK59692.1 - 0.00027 20.9 2.4 0.00027 20.9 2.4 5.2 5 2 1 6 6 6 1 Domain of unknown function (DUF5595) Golgin_A5 PF09787.9 KIK59692.1 - 0.0039 16.7 10.9 0.0039 16.7 10.9 3.0 2 1 1 3 3 3 1 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 KIK59692.1 - 0.0089 16.2 5.2 0.0089 16.2 5.2 3.9 3 1 1 4 4 4 1 Tropomyosin like Nuf2 PF03800.14 KIK59692.1 - 0.053 13.6 0.3 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Nuf2 family NdhM PF10664.9 KIK59692.1 - 0.95 9.7 6.8 3.9 7.8 0.3 3.3 2 1 1 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M DUF4200 PF13863.6 KIK59692.1 - 4.3 7.8 41.5 3.4 8.1 1.8 4.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF2935 PF11155.8 KIK59692.1 - 5.6 7.3 9.1 3.3 8.0 1.1 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Lebercilin PF15619.6 KIK59692.1 - 8.3 6.0 35.1 0.55 9.9 18.9 3.7 2 2 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KIK59692.1 - 8.7 6.5 27.1 6.5 6.9 4.9 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIK59692.1 - 9.6 6.3 26.0 0.92 9.6 3.7 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Mog1 PF04603.12 KIK59693.1 - 1.7e-40 138.5 0.1 2.1e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF2383 PF09537.10 KIK59694.1 - 0.001 19.4 12.8 0.023 15.0 0.6 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF2383) NRBF2_MIT PF17169.4 KIK59694.1 - 0.013 15.7 1.4 0.013 15.7 1.4 2.2 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 Med21 PF11221.8 KIK59694.1 - 0.058 13.7 0.8 0.058 13.7 0.8 3.5 4 1 0 4 4 4 0 Subunit 21 of Mediator complex Fib_alpha PF08702.10 KIK59694.1 - 0.079 13.1 11.2 0.42 10.8 1.1 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 KIK59694.1 - 0.1 12.8 0.3 0.1 12.8 0.3 3.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 FapA PF03961.13 KIK59694.1 - 0.41 9.2 13.2 1.4 7.4 3.9 3.0 3 0 0 3 3 3 0 Flagellar Assembly Protein A PSD4 PF07631.11 KIK59694.1 - 1.2 9.7 4.9 0.79 10.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) DUF5320 PF17253.2 KIK59694.1 - 1.7 9.7 0.0 1.7 9.7 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF5595 PF18077.1 KIK59694.1 - 2.3 8.3 6.7 18 5.5 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF3972 PF13118.6 KIK59694.1 - 2.3 8.6 12.1 0.69 10.4 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) TSC22 PF01166.18 KIK59694.1 - 3.1 8.2 7.2 14 6.1 0.3 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family TolA_bind_tri PF16331.5 KIK59694.1 - 3.6 7.7 9.6 7 6.8 0.2 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KIK59694.1 - 5.5 7.5 9.2 24 5.4 1.2 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HECT PF00632.25 KIK59696.1 - 9.8e-94 314.3 0.0 1.3e-93 313.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIK59696.1 - 2e-36 123.7 17.4 4.2e-12 45.9 2.3 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIK59696.1 - 2.4e-20 72.7 0.2 6.9e-20 71.3 0.2 1.8 1 0 0 1 1 1 1 C2 domain Pox_MCEL PF03291.16 KIK59697.1 - 8.3e-89 298.0 0.0 1.1e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KIK59697.1 - 3.8e-15 56.4 0.0 9.4e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK59697.1 - 3.7e-14 52.8 0.0 5.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK59697.1 - 9.1e-13 48.8 0.0 1.6e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK59697.1 - 1.4e-10 41.6 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK59697.1 - 3.2e-09 36.8 0.0 5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIK59697.1 - 2.3e-05 23.7 0.0 5.5e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.14 KIK59697.1 - 0.00043 19.9 0.0 0.001 18.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KIK59697.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Polysacc_deac_1 PF01522.21 KIK59698.1 - 4.9e-25 87.8 0.0 1.8e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase ERAP1_C PF11838.8 KIK59699.1 - 2.6e-70 237.4 0.5 5.1e-70 236.5 0.5 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KIK59699.1 - 1.4e-67 227.5 0.0 2.3e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIK59699.1 - 3e-46 158.0 2.0 1.5e-45 155.7 1.8 2.2 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 KIK59699.1 - 0.021 15.2 0.0 0.32 11.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold Spc24 PF08286.11 KIK59700.1 - 3.5e-18 65.8 4.6 8.2e-18 64.6 0.0 2.4 2 1 1 3 3 3 1 Spc24 subunit of Ndc80 Med9 PF07544.13 KIK59700.1 - 0.059 13.5 4.4 4.5 7.4 0.2 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AvrM-A PF18241.1 KIK59700.1 - 0.067 13.6 3.1 0.13 12.6 3.1 1.4 1 0 0 1 1 1 0 Flax-rust effector AvrM-A RNA_pol_Rpb4 PF03874.16 KIK59700.1 - 0.16 12.3 3.7 0.32 11.3 3.9 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb4 FAM76 PF16046.5 KIK59700.1 - 0.23 10.8 3.0 0.28 10.5 3.0 1.2 1 0 0 1 1 1 0 FAM76 protein Sec2p PF06428.11 KIK59700.1 - 0.56 10.2 7.9 7.6 6.6 7.1 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 KIK59700.1 - 0.63 10.7 4.5 8.2 7.1 0.1 2.7 3 0 0 3 3 3 0 SlyX Fib_alpha PF08702.10 KIK59700.1 - 0.78 9.9 4.8 0.96 9.6 3.1 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KIK59700.1 - 1.3 8.2 4.6 1.7 7.8 4.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 KIK59700.1 - 1.6 8.8 11.3 0.11 12.6 2.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding T2SSM PF04612.12 KIK59700.1 - 2.4 8.2 7.9 6.2 6.8 3.2 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M OmpH PF03938.14 KIK59700.1 - 2.9 8.2 10.6 5.3 7.4 3.6 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) THOC7 PF05615.13 KIK59700.1 - 4.2 7.6 10.4 7.4 6.9 2.5 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DUF148 PF02520.17 KIK59700.1 - 4.4 7.4 8.5 14 5.9 6.8 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 DivIVA PF05103.13 KIK59700.1 - 4.8 7.3 12.9 4 7.5 4.9 1.9 1 1 1 2 2 2 0 DivIVA protein HSP70 PF00012.20 KIK59701.1 - 4e-237 788.2 5.6 4.8e-237 787.9 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK59701.1 - 7.7e-17 61.1 0.7 9.3e-16 57.5 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KIK59701.1 - 0.0076 15.8 0.1 2.1 7.8 0.1 2.6 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 KIK59701.1 - 0.0083 15.2 1.4 0.1 11.6 0.3 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KIK59701.1 - 0.036 13.3 0.2 0.086 12.1 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KIK59701.1 - 0.037 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Zincin_2 PF10103.9 KIK59701.1 - 0.049 12.9 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase StbA PF06406.11 KIK59701.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 StbA protein Ribosomal_S2 PF00318.20 KIK59702.1 - 6.7e-57 192.2 0.0 7.2e-32 110.4 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Phosphatase PF15698.5 KIK59702.1 - 0.062 12.4 0.2 0.31 10.1 0.0 2.1 2 1 0 2 2 2 0 Phosphatase Lipoprotein_16 PF03923.13 KIK59702.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized lipoprotein Chorismate_bind PF00425.18 KIK59703.1 - 5.4e-90 301.4 0.0 7.9e-90 300.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KIK59703.1 - 4.3e-28 98.3 0.0 2.3e-27 96.0 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region SHQ1 PF04925.15 KIK59704.1 - 2.7e-57 193.2 0.0 4.6e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 SHQ1 protein CBP4 PF07960.11 KIK59707.1 - 1.6e-10 41.0 0.0 1.6e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 KIK59707.1 - 0.0024 17.8 0.1 0.0037 17.1 0.1 1.3 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Spem1 PF15670.5 KIK59708.1 - 0.0075 15.9 3.1 0.018 14.7 3.1 1.6 1 0 0 1 1 1 1 Spermatid maturation protein 1 Nuc_sug_transp PF04142.15 KIK59709.1 - 2.9e-07 30.0 0.3 4.9e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KIK59709.1 - 2e-05 24.1 6.0 4e-05 23.1 0.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KIK59709.1 - 3.4e-05 24.0 27.7 7.1e-05 23.0 4.9 2.6 2 0 0 2 2 2 2 EamA-like transporter family SMP_LBD PF17047.5 KIK59709.1 - 0.086 12.3 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain CRT-like PF08627.10 KIK59709.1 - 1.4 7.8 8.9 0.54 9.1 1.6 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like zf-C3HC4_3 PF13920.6 KIK59710.1 - 0.0093 15.8 9.2 0.019 14.8 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FliO PF04347.13 KIK59710.1 - 0.052 13.9 0.0 0.2 11.9 0.0 2.1 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO Zn-C2H2_12 PF18112.1 KIK59710.1 - 0.18 12.3 0.6 0.43 11.1 0.6 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_2 PF13639.6 KIK59710.1 - 0.2 12.0 11.0 0.33 11.3 11.0 1.4 1 0 0 1 1 1 0 Ring finger domain E1-E2_ATPase PF00122.20 KIK59711.1 - 2.5e-53 180.3 6.3 8.5e-53 178.6 2.9 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIK59711.1 - 3.3e-45 154.1 9.6 3.3e-45 154.1 9.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIK59711.1 - 5.8e-24 85.6 0.9 3.5e-23 83.0 0.5 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK59711.1 - 2.5e-22 78.3 0.1 1.6e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KIK59711.1 - 3e-18 65.7 0.0 5.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK59711.1 - 3.3e-07 30.3 1.2 7.4e-06 25.9 1.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK59711.1 - 3.6e-06 27.5 0.0 8.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 KIK59711.1 - 0.099 12.6 0.4 8.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KIK59713.1 - 1.9e-11 44.1 0.0 2.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK59713.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK59713.1 - 5.5e-07 30.3 0.0 1e-06 29.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK59713.1 - 1.7e-06 28.6 0.0 2.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK59713.1 - 0.00038 20.3 0.0 0.00076 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK59713.1 - 0.23 10.8 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DPBB_1 PF03330.18 KIK59714.1 - 0.00027 21.1 0.1 0.00093 19.4 0.0 1.9 1 1 1 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KIK59714.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Barwin family SOG2 PF10428.9 KIK59714.1 - 5.5 6.1 21.4 7.5 5.6 21.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sec34 PF04136.15 KIK59715.1 - 3.8e-39 133.9 0.0 8.8e-39 132.8 0.0 1.7 1 0 0 1 1 1 1 Sec34-like family MFS_1 PF07690.16 KIK59716.1 - 1.9e-33 115.9 58.3 1.9e-33 115.9 58.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily CDP-OH_P_transf PF01066.21 KIK59716.1 - 0.15 12.8 0.2 0.15 12.8 0.2 4.0 4 2 0 4 4 4 0 CDP-alcohol phosphatidyltransferase DUF4519 PF15012.6 KIK59716.1 - 0.91 9.7 0.0 0.91 9.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Lipase_GDSL PF00657.22 KIK59717.1 - 6e-10 39.4 0.0 8.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK59717.1 - 0.00088 19.7 1.7 0.0019 18.6 0.9 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Rol_Rep_N PF18106.1 KIK59717.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain RCC1 PF00415.18 KIK59718.1 - 2.1e-19 69.9 3.2 5.3e-09 36.6 0.2 7.6 7 1 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK59718.1 - 2.2e-11 43.2 14.2 1.1e-06 28.3 0.2 6.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PQQ PF01011.21 KIK59718.1 - 0.086 12.8 0.0 0.33 10.9 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat AMP-binding PF00501.28 KIK59720.1 - 2.5e-17 62.6 0.0 3.6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.19 KIK59721.1 - 1e-21 77.1 0.1 1e-21 77.1 0.1 2.6 3 1 0 3 3 3 1 linker histone H1 and H5 family TFIIA PF03153.13 KIK59722.1 - 0.45 10.5 13.7 0.25 11.3 8.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RPA_C PF08784.11 KIK59723.1 - 1.5e-09 38.4 0.1 3.1e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KIK59723.1 - 1.6e-06 28.0 1.2 2.5e-06 27.4 1.2 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KIK59723.1 - 0.0021 17.9 0.6 0.0033 17.2 0.6 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti_2 PF13742.6 KIK59723.1 - 0.13 12.5 1.2 0.16 12.2 0.3 1.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Serinc PF03348.15 KIK59724.1 - 1.2e-153 512.0 10.0 1.4e-153 511.8 10.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Adaptin_N PF01602.20 KIK59725.1 - 3.2e-119 398.9 1.7 4.8e-119 398.3 1.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK59725.1 - 2.2e-16 60.3 5.3 2.2e-12 47.3 0.1 3.9 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK59725.1 - 4.6e-09 36.6 0.3 0.013 15.9 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KIK59725.1 - 1.4e-06 28.0 7.6 0.32 11.4 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat Mpp10 PF04006.12 KIK59725.1 - 3.5e-05 22.5 13.0 5e-05 21.9 13.0 1.2 1 0 0 1 1 1 1 Mpp10 protein HEAT_EZ PF13513.6 KIK59725.1 - 0.0097 16.4 2.1 8.7 7.0 0.1 5.8 7 1 1 8 8 8 1 HEAT-like repeat TIP120 PF08623.10 KIK59725.1 - 0.033 14.0 4.2 1.8 8.3 0.6 2.7 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) PPP4R2 PF09184.11 KIK59725.1 - 0.24 11.0 14.6 0.42 10.2 14.6 1.4 1 0 0 1 1 1 0 PPP4R2 MFS_1 PF07690.16 KIK59726.1 - 6.4e-42 143.7 30.8 6.4e-42 143.7 30.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIK59726.1 - 0.0024 16.8 1.1 0.0024 16.8 1.1 3.2 3 1 1 4 4 4 2 MFS_1 like family DUF5326 PF17260.2 KIK59726.1 - 0.2 11.8 3.2 21 5.4 1.5 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) MFS_1 PF07690.16 KIK59727.1 - 1.4e-38 132.7 28.5 1.4e-38 132.7 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Linker_histone PF00538.19 KIK59728.1 - 3.8e-25 88.0 1.1 7e-25 87.2 0.0 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family IBR PF01485.21 KIK59729.1 - 4.5e-07 30.0 31.8 6.4e-05 23.1 5.7 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KIK59729.1 - 1.6 9.0 0.0 1.6 9.0 0.0 5.3 6 0 0 6 6 6 0 zinc-ribbon Telomere_reg-2 PF10193.9 KIK59730.1 - 5.9e-32 110.4 0.2 1.2e-31 109.3 0.2 1.6 1 0 0 1 1 1 1 Telomere length regulation protein ZapC PF07126.12 KIK59730.1 - 0.091 12.3 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Cell-division protein ZapC Mistic PF11458.8 KIK59730.1 - 0.22 11.5 0.3 21 5.2 0.0 2.4 2 0 0 2 2 2 0 Membrane-integrating protein Mistic MT0933_antitox PF14013.6 KIK59730.1 - 0.24 11.7 1.9 7.2 7.0 0.8 2.3 2 0 0 2 2 2 0 MT0933-like antitoxin protein Sfi1 PF08457.10 KIK59731.1 - 1.3e-26 93.3 98.9 5.1e-15 55.0 73.5 5.0 1 1 2 3 3 3 3 Sfi1 spindle body protein DUF3078 PF11276.8 KIK59731.1 - 0.05 14.1 4.1 4.5 7.8 0.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3078) Alpha-2-MRAP_N PF06400.11 KIK59731.1 - 0.17 11.9 5.4 0.11 12.5 1.9 2.6 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain PIG-Y PF15159.6 KIK59732.1 - 1.6e-20 73.8 4.8 1.8e-20 73.6 4.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PSI_PsaF PF02507.15 KIK59732.1 - 0.05 13.4 0.2 0.055 13.3 0.2 1.1 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III ATG16 PF08614.11 KIK59733.1 - 0.00044 20.6 3.8 0.00047 20.4 3.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIK59733.1 - 0.0018 18.8 2.5 0.002 18.6 2.5 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 KIK59733.1 - 0.0042 16.4 1.4 0.0052 16.1 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KIK59733.1 - 0.0068 16.5 2.4 0.0079 16.3 2.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Rx_N PF18052.1 KIK59733.1 - 0.017 15.4 3.3 0.023 14.9 3.3 1.2 1 0 0 1 1 1 0 Rx N-terminal domain YabA PF06156.13 KIK59733.1 - 0.026 15.2 2.3 0.036 14.7 2.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Ax_dynein_light PF10211.9 KIK59733.1 - 0.032 14.2 5.3 0.043 13.8 5.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.14 KIK59733.1 - 0.032 14.5 3.8 0.045 14.1 3.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.18 KIK59733.1 - 0.056 13.7 2.6 0.056 13.7 2.6 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4140 PF13600.6 KIK59733.1 - 0.06 13.8 1.4 0.077 13.4 1.4 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FAA_hydro_N_2 PF18288.1 KIK59733.1 - 0.076 13.4 0.2 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 TMF_DNA_bd PF12329.8 KIK59733.1 - 0.076 13.0 9.6 0.12 12.4 9.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 KIK59733.1 - 0.079 13.3 3.4 0.13 12.6 3.4 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 KIK59733.1 - 0.22 12.0 8.7 0.36 11.3 8.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB V_ATPase_I PF01496.19 KIK59733.1 - 0.24 9.3 0.6 0.28 9.1 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.16 KIK59733.1 - 0.34 9.4 2.3 0.45 9.0 2.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.15 KIK59733.1 - 0.39 10.5 8.9 0.62 9.9 8.5 1.5 1 1 0 1 1 1 0 Septum formation initiator Spc24 PF08286.11 KIK59733.1 - 0.54 10.5 4.5 0.83 9.9 4.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 KIK59733.1 - 0.64 10.1 4.9 1 9.5 4.9 1.3 1 0 0 1 1 1 0 Swi5 ox_reductase_C PF08635.10 KIK59734.1 - 4.6e-74 246.8 0.2 6.8e-74 246.2 0.2 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KIK59734.1 - 2e-22 80.3 0.0 7e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK59734.1 - 0.0042 17.1 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NES_C_h PF18208.1 KIK59734.1 - 0.16 12.2 0.0 0.56 10.5 0.0 1.8 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Peptidase_A4 PF01828.17 KIK59735.1 - 2.7e-66 223.0 15.7 4.2e-66 222.4 15.7 1.3 1 0 0 1 1 1 1 Peptidase A4 family zf-C2HE PF16278.5 KIK59736.1 - 1.8e-16 60.3 1.5 2.7e-16 59.7 0.3 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KIK59736.1 - 2.5e-13 50.5 0.7 1.9e-12 47.7 0.7 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIK59736.1 - 1.8e-08 35.0 0.2 1.2e-07 32.3 0.2 2.1 1 1 0 1 1 1 1 HIT domain Dynein_light PF01221.18 KIK59736.1 - 0.0059 16.9 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 Dynein light chain type 1 Hira PF07569.11 KIK59736.1 - 0.077 12.7 0.8 0.14 11.8 0.8 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split RabGAP-TBC PF00566.18 KIK59737.1 - 6.6e-43 146.9 6.2 3.4e-40 138.0 3.4 2.5 1 1 1 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KIK59737.1 - 2.5e-07 30.3 0.0 1.5e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Rab-binding domain (RBD) Ribosomal_S21e PF01249.18 KIK59738.1 - 3e-40 136.2 0.1 3.3e-40 136.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF917 PF06032.12 KIK59738.1 - 0.068 12.0 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF917) FAA_hydrolase PF01557.18 KIK59739.1 - 1.9e-53 181.4 0.0 2.5e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 2OG-FeII_Oxy_2 PF13532.6 KIK59740.1 - 3e-31 109.2 0.0 1.1e-29 104.0 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily LETM1 PF07766.13 KIK59741.1 - 4.3e-103 344.3 0.7 4.3e-103 344.3 0.7 2.1 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KIK59741.1 - 0.0012 18.6 0.5 0.0084 15.8 0.0 2.7 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 KIK59741.1 - 0.0023 18.4 1.0 0.19 12.2 0.0 4.0 3 1 2 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK59741.1 - 0.004 17.0 0.0 2.5 8.3 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KIK59741.1 - 0.071 12.7 0.0 0.77 9.4 0.0 2.8 2 0 0 2 2 2 0 EF hand ALMT PF11744.8 KIK59741.1 - 2.7 6.7 6.8 4.6 6.0 6.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter SHR3_chaperone PF08229.11 KIK59742.1 - 1.8e-38 131.4 0.0 2.1e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.6 KIK59742.1 - 0.035 14.5 0.1 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) RsfS PF02410.15 KIK59743.1 - 2.2e-06 28.0 0.0 3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation G-patch PF01585.23 KIK59745.1 - 1.1e-10 41.2 2.5 2.9e-10 39.9 2.5 1.7 1 0 0 1 1 1 1 G-patch domain ANAPC_CDC26 PF10471.9 KIK59745.1 - 0.1 13.5 2.6 1.8 9.5 0.6 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 FAD_binding_2 PF00890.24 KIK59746.1 - 5.2e-126 421.1 3.0 6.5e-126 420.8 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIK59746.1 - 1.1e-42 145.0 0.1 1.7e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 KIK59746.1 - 1.3e-05 24.5 2.0 0.0097 15.0 2.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIK59746.1 - 1.4e-05 24.5 1.4 0.0018 17.6 0.6 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK59746.1 - 4.2e-05 22.9 0.1 0.032 13.5 0.0 2.6 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 KIK59746.1 - 0.0027 17.0 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIK59746.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KIK59746.1 - 0.052 13.1 1.4 0.15 11.6 1.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK59746.1 - 0.16 10.7 2.9 0.43 9.2 0.6 2.6 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK59746.1 - 1.9 7.7 3.5 2.8 7.1 1.3 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RabGAP-TBC PF00566.18 KIK59747.1 - 2.5e-31 109.0 0.2 6.8e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fungal_trans PF04082.18 KIK59748.1 - 4.8e-15 55.3 0.0 1.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK59748.1 - 0.00012 22.1 13.1 0.00023 21.2 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T4SS PF07996.11 KIK59748.1 - 0.027 14.9 0.2 0.045 14.2 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins DUF1003 PF06210.11 KIK59748.1 - 0.074 13.2 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) PhoD PF09423.10 KIK59749.1 - 2.1e-102 342.8 2.0 2.5e-102 342.5 2.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KIK59749.1 - 4.8e-23 81.5 0.0 1e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KIK59749.1 - 0.00032 21.2 0.1 0.00099 19.6 0.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain HSP70 PF00012.20 KIK59750.1 - 1.9e-260 865.2 4.7 2.2e-260 865.0 4.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK59750.1 - 8.7e-16 57.6 0.1 2.1e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KIK59750.1 - 0.0022 17.7 0.0 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KIK59750.1 - 0.032 13.5 1.1 0.063 12.5 0.3 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 KIK59750.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein Raco_middle PF17651.1 KIK59750.1 - 0.13 12.0 0.0 7.9 6.1 0.0 3.0 3 0 0 3 3 3 0 RACo middle region HbrB PF08539.11 KIK59751.1 - 7.7e-28 97.6 0.0 1.2e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Oxygenase-NA PF09859.9 KIK59751.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Creb_binding PF09030.10 KIK59751.1 - 2.1 9.1 7.3 0.22 12.2 0.5 2.3 2 0 0 2 2 2 0 Creb binding B56 PF01603.20 KIK59752.1 - 2.1e-191 636.4 4.5 2.5e-191 636.2 4.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Citrate_synt PF00285.21 KIK59754.1 - 5.6e-98 328.3 0.0 6.8e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sec66 PF09802.9 KIK59755.1 - 2.1e-55 187.1 0.0 2.7e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SKG6 PF08693.10 KIK59755.1 - 0.021 14.2 0.7 0.036 13.5 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain USP7_ICP0_bdg PF12436.8 KIK59756.1 - 8.2e-81 270.8 0.1 7.1e-80 267.8 0.0 2.5 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KIK59756.1 - 1.6e-67 227.2 2.5 1.4e-64 217.6 0.1 3.0 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KIK59756.1 - 3e-49 167.8 0.1 4.8e-49 167.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK59756.1 - 1.7e-20 73.8 0.0 3.7e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KIK59756.1 - 1.1e-07 32.0 0.0 5.7e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 KIK59756.1 - 0.0058 16.4 0.2 0.8 9.5 0.0 4.0 4 0 0 4 4 4 1 Ubiquitin family Rad17 PF03215.15 KIK59756.1 - 0.04 13.8 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain CRPV_capsid PF08762.10 KIK59756.1 - 0.15 11.7 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 CRPV capsid protein like DNA_primase_lrg PF04104.14 KIK59758.1 - 4.8e-75 252.4 0.0 6.8e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CDP-OH_P_transf PF01066.21 KIK59759.1 - 1.3e-11 45.1 2.1 1.5e-11 44.9 0.3 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SMC_Nse1 PF07574.13 KIK59760.1 - 1.3e-32 113.3 2.6 1.3e-32 113.3 2.6 2.3 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KIK59760.1 - 6.7e-11 42.3 12.7 1.1e-10 41.6 12.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KIK59760.1 - 6.8e-06 26.3 9.9 1.2e-05 25.6 9.9 1.4 1 0 0 1 1 1 1 Ring finger domain NOA36 PF06524.12 KIK59760.1 - 1.8e-05 24.3 12.3 3.1e-05 23.5 12.3 1.3 1 0 0 1 1 1 1 NOA36 protein zf-HC5HC2H PF13771.6 KIK59760.1 - 0.0069 16.6 7.1 0.018 15.3 7.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIK59760.1 - 0.013 15.6 3.8 0.028 14.6 3.8 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_2 PF13923.6 KIK59760.1 - 0.018 14.9 10.3 0.029 14.2 10.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SAPS PF04499.15 KIK59760.1 - 0.29 9.9 4.7 0.45 9.2 4.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-RING_10 PF16685.5 KIK59760.1 - 0.43 10.8 6.2 0.74 10.0 6.2 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 KIK59760.1 - 0.58 10.1 9.0 0.99 9.3 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK59760.1 - 1.1 9.7 9.2 2.8 8.3 9.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF4746 PF15928.5 KIK59760.1 - 2 7.8 11.3 3.2 7.1 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PHD PF00628.29 KIK59760.1 - 2.8 7.9 9.7 9.8 6.2 9.9 1.9 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KIK59760.1 - 5.2 7.0 9.8 4.4 7.3 8.0 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 KIK59760.1 - 8.5 6.3 9.4 7.1 6.5 7.3 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain eIF3_subunit PF08597.10 KIK59760.1 - 9.5 6.0 23.5 19 5.1 23.5 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AAA PF00004.29 KIK59761.1 - 1.1e-35 123.0 0.0 2e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK59761.1 - 4e-10 39.3 0.0 9.4e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK59761.1 - 3.1e-06 27.7 0.0 0.0054 17.1 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 KIK59761.1 - 0.00026 21.5 0.0 0.035 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK59761.1 - 0.00072 19.6 0.4 0.016 15.2 0.1 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK59761.1 - 0.00077 19.5 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KIK59761.1 - 0.001 19.3 0.5 0.043 14.1 0.1 2.8 2 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KIK59761.1 - 0.0015 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 KIK59761.1 - 0.0026 16.8 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_24 PF13479.6 KIK59761.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK59761.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KIK59761.1 - 0.032 14.2 0.2 0.27 11.2 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KIK59761.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein IPT PF01745.16 KIK59761.1 - 0.063 12.7 0.1 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_28 PF13521.6 KIK59761.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK59761.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KIK59761.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 KIK59761.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KIK59761.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIK59761.1 - 0.16 11.4 0.0 3.2 7.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 KIK59761.1 - 0.2 12.1 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ion_trans PF00520.31 KIK59763.1 - 0.00033 20.0 0.1 0.00043 19.6 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein FUN14 PF04930.15 KIK59766.1 - 2.8e-18 66.1 2.1 3.8e-18 65.7 2.1 1.2 1 0 0 1 1 1 1 FUN14 family Methyltr_RsmB-F PF01189.17 KIK59768.1 - 1.6e-76 256.4 0.0 2.1e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KIK59768.1 - 2.3e-08 34.4 0.0 7.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KIK59768.1 - 0.00037 20.3 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KIK59768.1 - 0.0033 17.2 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KIK59768.1 - 0.029 15.1 0.0 0.083 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KIK59768.1 - 0.046 13.8 0.1 0.091 12.9 0.1 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KIK59768.1 - 0.057 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KIK59768.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SUR7 PF06687.12 KIK59769.1 - 1.4e-22 80.4 15.2 1.7e-22 80.1 15.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family PMP22_Claudin PF00822.20 KIK59769.1 - 0.2 11.5 7.6 2.6 7.9 0.1 2.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF4293 PF14126.6 KIK59769.1 - 3 8.1 10.1 24 5.2 10.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) W2 PF02020.18 KIK59771.1 - 5.3e-12 45.7 0.6 5.3e-12 45.7 0.6 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KIK59771.1 - 1.1e-11 43.9 10.2 0.00039 20.0 4.7 3.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KIK59771.1 - 8e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KIK59771.1 - 1.7e-06 27.2 0.3 3.7e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KIK59771.1 - 0.00024 21.5 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KIK59771.1 - 0.001 17.3 3.2 0.0017 16.5 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KIK59771.1 - 0.016 14.9 16.5 0.22 11.3 4.6 4.4 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Polyoma_lg_T_C PF06431.11 KIK59771.1 - 7.9 5.2 6.1 20 3.9 6.1 1.6 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Pmp3 PF01679.17 KIK59772.1 - 3.1e-24 84.9 6.2 3.4e-24 84.8 6.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Abhydrolase_3 PF07859.13 KIK59773.1 - 3.7e-10 40.0 0.0 4.9e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK59773.1 - 0.00012 22.8 0.2 0.00016 22.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK59773.1 - 0.053 12.8 0.0 2.2 7.5 0.0 2.3 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIK59773.1 - 0.12 11.9 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aminotran_5 PF00266.19 KIK59774.1 - 9.4e-12 44.6 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.19 KIK59775.1 - 6.4e-10 38.8 0.0 9.5e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KIK59775.1 - 0.0027 16.8 0.0 0.021 13.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase AT_hook PF02178.19 KIK59776.1 - 1.8e-06 27.1 54.1 0.0046 16.7 4.7 4.6 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.13 KIK59777.1 - 1.1e-14 55.2 0.1 2.6e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KIK59777.1 - 0.0046 16.7 0.4 0.018 14.7 0.4 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase PF00069.25 KIK59778.1 - 3.7e-46 157.6 0.0 5e-45 153.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK59778.1 - 2.9e-28 98.9 0.0 5e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK59778.1 - 0.0052 16.7 0.0 0.026 14.4 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Adeno_E1B_55K_N PF04623.12 KIK59778.1 - 1.2 9.9 3.7 26 5.6 0.3 3.8 4 0 0 4 4 4 0 Adenovirus E1B protein N-terminus Amidohydro_1 PF01979.20 KIK59779.1 - 6.2e-70 236.2 0.0 1e-69 235.5 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK59779.1 - 7e-12 45.6 0.1 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KIK59779.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase SLD5_C PF16922.5 KIK59780.1 - 9.8e-12 44.9 0.0 2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KIK59780.1 - 0.00022 21.7 2.6 0.0016 18.8 2.6 2.1 1 1 0 1 1 1 1 GINS complex protein Methyltransf_16 PF10294.9 KIK59781.1 - 3.2e-17 62.8 0.0 2.9e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KIK59781.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) XLF PF09302.11 KIK59781.1 - 0.1 12.8 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Lipase_3 PF01764.25 KIK59782.1 - 4.8e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK59782.1 - 0.0011 19.6 0.1 0.0014 19.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KIK59782.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 KIK59782.1 - 0.031 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK59782.1 - 0.049 12.9 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIK59782.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK59782.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RhoGEF PF00621.20 KIK59783.1 - 1.6e-18 67.6 0.1 9.3e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Far-17a_AIG1 PF04750.14 KIK59784.1 - 1.5e-30 106.1 2.2 1.8e-30 105.8 2.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Lyase_1 PF00206.20 KIK59785.1 - 5.8e-95 318.3 0.0 9e-95 317.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KIK59785.1 - 3.4e-25 88.6 0.1 9.3e-25 87.2 0.1 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Syntaxin PF00804.25 KIK59786.1 - 2.2e-34 118.9 7.9 3.7e-34 118.1 7.9 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KIK59786.1 - 8.2e-09 35.3 0.1 1.9e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KIK59786.1 - 1.6e-07 31.6 11.0 2.1e-07 31.2 5.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein VitD-bind_III PF09164.10 KIK59786.1 - 0.0037 17.2 0.1 0.0091 16.0 0.1 1.6 1 0 0 1 1 1 1 Vitamin D binding protein, domain III Spectrin PF00435.21 KIK59786.1 - 0.0083 16.6 4.5 0.93 10.0 0.0 3.0 3 0 0 3 3 3 2 Spectrin repeat MCPsignal PF00015.21 KIK59786.1 - 0.01 15.7 1.5 0.01 15.7 1.5 2.3 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Use1 PF09753.9 KIK59786.1 - 0.016 14.9 4.3 0.026 14.3 4.0 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 DASH_Dam1 PF08653.10 KIK59786.1 - 0.089 12.6 0.3 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 SKA1 PF07160.12 KIK59786.1 - 0.17 11.7 8.9 0.079 12.8 1.0 2.7 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Ribosomal_S11 PF00411.19 KIK59786.1 - 0.3 11.5 2.1 17 5.9 0.2 3.1 3 0 0 3 3 3 0 Ribosomal protein S11 DUF4988 PF16378.5 KIK59786.1 - 0.41 10.3 5.4 14 5.3 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function DUF2939 PF11159.8 KIK59786.1 - 0.58 10.6 3.5 1.2 9.6 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Vac_Fusion PF02346.16 KIK59786.1 - 0.67 9.6 2.9 0.87 9.3 0.1 2.5 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF948 PF06103.11 KIK59786.1 - 0.73 10.1 5.5 3.8 7.8 0.5 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) End3 PF12761.7 KIK59786.1 - 1.3 9.2 13.7 0.44 10.7 2.1 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FUSC PF04632.12 KIK59786.1 - 1.7 7.1 6.6 0.32 9.5 1.7 1.9 1 1 0 2 2 2 0 Fusaric acid resistance protein family DUF16 PF01519.16 KIK59786.1 - 2 9.0 7.2 0.44 11.1 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4094 PF13334.6 KIK59786.1 - 2.2 8.7 5.4 7.5 7.0 1.2 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4094) V-SNARE PF05008.15 KIK59786.1 - 9.2 6.7 14.9 0.31 11.5 0.7 3.7 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-AN1 PF01428.16 KIK59787.1 - 1.5e-10 41.1 6.8 1.5e-10 41.1 6.8 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 KIK59787.1 - 0.0022 17.7 0.6 0.0022 17.7 0.6 1.9 2 0 0 2 2 2 1 Rubredoxin metal binding domain IBR PF01485.21 KIK59787.1 - 0.03 14.6 8.4 0.033 14.4 7.5 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Aminotran_1_2 PF00155.21 KIK59788.1 - 8.6e-89 298.2 0.0 9.8e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_8C PF08437.10 KIK59788.1 - 0.18 11.9 0.2 0.5 10.5 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 8 C-terminal HEAT_2 PF13646.6 KIK59789.1 - 4e-14 52.8 8.5 0.0038 17.6 0.3 7.5 5 3 3 8 8 8 4 HEAT repeats HEAT PF02985.22 KIK59789.1 - 3.2e-13 48.7 14.9 0.82 10.1 0.0 10.0 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.6 KIK59789.1 - 1.1e-09 38.6 11.3 0.089 13.3 0.0 7.3 7 0 0 7 7 7 3 HEAT-like repeat Cnd1 PF12717.7 KIK59789.1 - 0.00018 21.6 0.2 0.029 14.4 0.0 3.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF1981 PF09324.10 KIK59789.1 - 0.011 15.6 0.0 0.91 9.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Adaptin_N PF01602.20 KIK59789.1 - 0.016 13.8 0.4 0.47 8.9 0.1 2.6 1 1 0 2 2 2 0 Adaptin N terminal region TMEM251 PF15190.6 KIK59790.1 - 0.035 14.1 0.8 0.069 13.1 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 251 DUF4064 PF13273.6 KIK59790.1 - 3.2 8.1 9.0 2.1 8.7 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) EMC3_TMCO1 PF01956.16 KIK59790.1 - 5 6.8 6.3 0.5 10.1 0.6 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Zn_clus PF00172.18 KIK59791.1 - 2.9 8.1 11.9 1.5 9.0 2.7 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CDP-OH_P_transf PF01066.21 KIK59795.1 - 1.5e-12 48.1 0.3 1.5e-12 48.1 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Asn_synthase PF00733.21 KIK59796.1 - 5e-94 315.9 0.1 4.2e-56 191.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KIK59796.1 - 1.3e-33 115.5 0.0 2.1e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIK59796.1 - 1.1e-27 96.9 0.0 1.8e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KIK59796.1 - 0.00069 19.1 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 KIK59796.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KIK59796.1 - 0.013 14.6 0.0 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 NAD synthase Voldacs PF03517.13 KIK59797.1 - 9.8e-32 110.0 0.1 1.4e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF4611 PF15387.6 KIK59797.1 - 1.7 8.9 7.9 0.2 11.9 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DEAD PF00270.29 KIK59798.1 - 2.7e-45 154.3 0.0 2.2e-44 151.3 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK59798.1 - 2.5e-28 98.7 0.1 6.4e-27 94.1 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK59798.1 - 9.8e-05 22.4 0.1 0.00028 21.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CAP_N PF01213.19 KIK59798.1 - 1.1 8.6 6.8 2.3 7.6 6.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF_assoc_2 PF08356.12 KIK59799.1 - 0.0005 20.0 0.1 0.00067 19.6 0.1 1.2 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KIK59799.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 EF hand associated EF-hand_8 PF13833.6 KIK59799.1 - 0.058 13.2 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Toprim_4 PF13662.6 KIK59799.1 - 0.21 12.1 0.0 0.29 11.7 0.0 1.2 1 0 0 1 1 1 0 Toprim domain MFS_1 PF07690.16 KIK59800.1 - 4.2e-15 55.5 34.0 1.7e-13 50.2 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ist1 PF03398.14 KIK59802.1 - 2e-43 148.2 0.0 3.1e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KIK59802.1 - 5.2e-07 29.5 0.0 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PIG-H PF10181.9 KIK59803.1 - 6.9e-18 64.3 0.0 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ALG3 PF05208.13 KIK59804.1 - 2.2e-139 464.9 11.8 2.7e-139 464.6 11.8 1.0 1 0 0 1 1 1 1 ALG3 protein DEAD PF00270.29 KIK59805.1 - 5.7e-50 169.5 0.0 9.4e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK59805.1 - 9.4e-31 106.4 0.0 4.4e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK59805.1 - 5.7e-06 26.4 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 KIK59806.1 - 2.9e-41 141.0 0.0 1.1e-40 139.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK59806.1 - 2.3e-09 37.0 0.0 7.1e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KIK59806.1 - 2.3e-08 34.1 0.0 6.7e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK59806.1 - 7.4e-08 33.0 1.0 2.7e-05 24.6 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KIK59806.1 - 1.8e-06 28.2 0.0 4.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KIK59806.1 - 2.3e-06 27.0 0.0 5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 KIK59806.1 - 8.3e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_28 PF13521.6 KIK59806.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KIK59806.1 - 0.00055 19.2 0.0 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 KIK59806.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIK59806.1 - 0.00073 19.5 0.0 0.014 15.4 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KIK59806.1 - 0.0008 19.4 0.0 0.0042 17.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KIK59806.1 - 0.00099 19.4 2.4 0.013 15.8 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KIK59806.1 - 0.001 19.6 0.0 0.02 15.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KIK59806.1 - 0.002 18.5 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KIK59806.1 - 0.0022 17.9 0.1 0.017 15.1 0.0 2.4 3 0 0 3 3 2 1 NTPase AAA_7 PF12775.7 KIK59806.1 - 0.0027 17.3 0.1 0.019 14.5 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KIK59806.1 - 0.004 16.9 0.1 0.0091 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK59806.1 - 0.0069 16.5 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK59806.1 - 0.0086 15.8 0.1 0.023 14.4 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein CENP-F_leu_zip PF10473.9 KIK59806.1 - 0.009 16.0 0.3 0.019 15.0 0.3 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mg_chelatase PF01078.21 KIK59806.1 - 0.0096 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK59806.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIK59806.1 - 0.012 15.0 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KIK59806.1 - 0.013 15.1 0.4 0.058 13.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KIK59806.1 - 0.02 14.8 0.1 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KIK59806.1 - 0.027 14.2 0.1 0.054 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIK59806.1 - 0.038 13.8 0.1 0.075 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AFG1_ATPase PF03969.16 KIK59806.1 - 0.04 12.8 0.1 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 KIK59806.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK59806.1 - 0.083 13.4 0.1 0.5 10.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KIK59806.1 - 0.085 12.8 2.0 0.66 9.8 0.0 2.9 4 1 0 4 4 4 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK59806.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 KIK59806.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 KIK59806.1 - 0.21 10.9 1.3 0.5 9.7 0.0 2.1 3 0 0 3 3 3 0 KaiC SKG6 PF08693.10 KIK59808.1 - 0.0032 16.8 2.6 0.008 15.6 2.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KIK59808.1 - 0.012 15.5 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 KIK59808.1 - 0.022 13.6 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2062 PF09835.9 KIK59808.1 - 0.022 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) BatD PF13584.6 KIK59808.1 - 0.022 13.6 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance PRIMA1 PF16101.5 KIK59808.1 - 0.025 14.6 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Herpes_gE PF02480.16 KIK59808.1 - 0.035 12.9 0.1 0.036 12.8 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 KIK59808.1 - 0.039 13.5 0.1 0.062 12.9 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 KIK59808.1 - 0.047 13.6 0.5 0.061 13.2 0.5 1.1 1 0 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.6 KIK59808.1 - 0.093 12.6 2.8 0.42 10.4 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 51 Peptidase_M56 PF05569.11 KIK59808.1 - 0.12 11.6 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4381 PF14316.6 KIK59808.1 - 0.14 12.4 0.2 0.19 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KIK59808.1 - 0.15 12.9 0.0 0.28 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 KIK59808.1 - 0.25 11.3 1.7 0.3 11.0 1.7 1.3 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mucin15 PF15672.5 KIK59808.1 - 4.3 6.7 11.1 4.9 6.5 7.2 2.0 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 NAC PF01849.18 KIK59809.1 - 1.8e-19 69.5 0.0 4e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 NAC domain Zip PF02535.22 KIK59809.1 - 0.11 11.6 0.5 0.12 11.6 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 KIK59809.1 - 6.2 6.2 13.5 9 5.6 13.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Methyltransf_11 PF08241.12 KIK59810.1 - 2.1e-05 25.1 0.0 7.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK59810.1 - 7.1e-05 23.4 0.0 0.0002 22.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK59810.1 - 0.0078 16.0 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK59810.1 - 0.03 15.1 0.0 0.057 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_28_C PF04101.16 KIK59811.1 - 5e-29 101.4 0.0 6e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain P5CR_dimer PF14748.6 KIK59812.1 - 3.7e-39 133.1 1.6 3.1e-38 130.2 0.8 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KIK59812.1 - 2.4e-10 40.9 0.1 4.2e-08 33.7 0.0 2.5 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.22 KIK59815.1 - 1.9e-11 43.6 0.0 4.9e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAPPC10 PF12584.8 KIK59816.1 - 8.5e-34 116.5 0.1 1.9e-33 115.3 0.1 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Aminotran_5 PF00266.19 KIK59817.1 - 4.3e-34 118.1 0.0 2.8e-33 115.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V HSP90 PF00183.18 KIK59819.1 - 3.9e-229 761.8 23.2 5e-229 761.5 23.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KIK59819.1 - 1.3e-14 54.7 0.1 2.3e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK59819.1 - 6.2e-10 39.0 0.2 1.6e-09 37.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Trimer_CC PF08954.11 KIK59820.1 - 0.025 14.2 4.0 0.23 11.0 0.8 3.3 2 0 0 2 2 2 0 Trimerisation motif DUF1727 PF08353.10 KIK59820.1 - 0.028 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) DUF1664 PF07889.12 KIK59820.1 - 0.16 12.0 11.2 1.9 8.5 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KIK59820.1 - 0.22 11.7 12.4 0.82 9.8 3.2 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KIK59820.1 - 0.57 10.6 30.6 0.17 12.3 9.1 3.1 1 1 2 3 3 3 0 Fez1 FH2 PF02181.23 KIK59820.1 - 0.82 8.7 15.2 0.66 9.0 0.5 3.4 2 1 0 3 3 3 0 Formin Homology 2 Domain XhlA PF10779.9 KIK59820.1 - 2.1 8.6 7.8 7.2 6.9 0.1 3.6 3 0 0 3 3 3 0 Haemolysin XhlA Tropomyosin_1 PF12718.7 KIK59820.1 - 4.9 7.3 29.0 2.2 8.4 2.2 3.4 1 1 2 3 3 3 0 Tropomyosin like TMPIT PF07851.13 KIK59820.1 - 6.1 6.0 14.8 0.98 8.6 4.3 2.7 1 1 1 2 2 2 0 TMPIT-like protein GAS PF13851.6 KIK59820.1 - 6.5 6.1 28.6 4.2 6.7 1.9 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Oxidored_FMN PF00724.20 KIK59821.1 - 1.6e-67 228.2 0.0 2e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIK59821.1 - 0.18 11.2 0.0 1.6 8.1 0.0 2.2 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel SNRNP27 PF08648.12 KIK59822.1 - 1.1e-30 105.4 1.9 2.3e-30 104.4 1.9 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF5305 PF17231.2 KIK59822.1 - 0.64 9.4 4.9 0.3 10.5 2.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) SUI1 PF01253.22 KIK59823.1 - 2e-28 98.7 0.2 2.7e-28 98.3 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.11 KIK59824.1 - 0.049 13.7 9.7 0.27 11.2 9.7 2.1 1 1 0 1 1 1 0 rRNA processing PPP4R2 PF09184.11 KIK59825.1 - 7.3e-24 84.9 0.0 9.4e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 PAP2 PF01569.21 KIK59826.1 - 1.6e-31 108.9 2.7 1.6e-31 108.9 2.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF2339 PF10101.9 KIK59826.1 - 0.024 13.3 0.8 0.032 12.8 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TspO_MBR PF03073.15 KIK59826.1 - 0.067 13.3 0.5 0.067 13.3 0.5 1.8 2 0 0 2 2 2 0 TspO/MBR family TF_Zn_Ribbon PF08271.12 KIK59827.1 - 0.0039 16.7 0.7 0.0087 15.6 0.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 KIK59827.1 - 0.028 14.4 0.4 0.17 12.0 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Glycos_transf_1 PF00534.20 KIK59828.1 - 1.6e-19 70.1 0.0 2.7e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK59828.1 - 4.3e-12 46.6 0.0 7.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIK59828.1 - 0.0023 18.3 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_3_3 PF13750.6 KIK59828.1 - 0.024 14.3 0.2 0.06 13.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DNA_pol_phi PF04931.13 KIK59830.1 - 2.2e-232 773.4 10.3 3.2e-232 772.9 10.3 1.2 1 0 0 1 1 1 1 DNA polymerase phi TPR_14 PF13428.6 KIK59830.1 - 0.0035 18.0 0.4 0.96 10.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2281 PF10047.9 KIK59830.1 - 0.029 15.1 0.6 1.5 9.5 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2281) SDA1 PF05285.12 KIK59830.1 - 0.75 9.2 19.6 1.7 8.0 19.6 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK59830.1 - 1.9 6.6 17.1 4 5.5 17.1 1.4 1 0 0 1 1 1 0 Nop14-like family Asp PF00026.23 KIK59831.1 - 4.4e-19 69.0 0.5 2.6e-08 33.7 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK59831.1 - 0.0012 19.1 0.0 0.0047 17.2 0.0 2.1 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK59831.1 - 0.015 16.0 0.1 3.4 8.4 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease MutS_V PF00488.21 KIK59832.1 - 2.3e-68 230.0 2.0 2.8e-68 229.6 0.1 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIK59832.1 - 9.6e-38 130.3 0.6 2.5e-37 129.0 0.6 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIK59832.1 - 3.9e-25 88.3 0.1 7.1e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIK59832.1 - 2.7e-09 37.4 0.3 1.3e-08 35.2 0.3 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KIK59832.1 - 0.00026 21.3 0.1 0.00068 19.9 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV Neuregulin PF02158.15 KIK59832.1 - 0.0059 16.0 4.5 0.46 9.8 3.8 2.2 2 0 0 2 2 2 2 Neuregulin intracellular region ATP12 PF07542.11 KIK59833.1 - 6.5e-42 142.7 0.3 1.2e-41 141.8 0.0 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein SIKE PF05769.11 KIK59834.1 - 1.2e-06 28.6 17.1 6.7e-06 26.2 9.9 2.4 2 0 0 2 2 2 2 SIKE family TACC_C PF05010.14 KIK59834.1 - 0.007 16.2 6.7 0.007 16.2 6.7 1.7 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ZapD PF07072.11 KIK59834.1 - 0.014 15.2 3.7 0.025 14.3 3.1 1.7 1 1 0 1 1 1 0 Cell division protein Tho2 PF11262.8 KIK59834.1 - 0.11 11.6 5.2 0.19 10.9 5.2 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nsp1_C PF05064.13 KIK59834.1 - 0.4 10.5 10.4 0.037 13.8 3.7 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region OmpH PF03938.14 KIK59834.1 - 1 9.7 9.1 2.2 8.6 9.1 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KIK59834.1 - 1.4 8.7 9.8 0.18 11.6 1.6 2.9 3 1 0 3 3 3 0 Septum formation initiator TMPIT PF07851.13 KIK59834.1 - 1.9 7.7 8.6 0.33 10.2 5.1 1.4 2 0 0 2 2 2 0 TMPIT-like protein DUF4578 PF15147.6 KIK59834.1 - 1.9 9.4 6.9 5.4 7.9 1.6 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4578) DUF4407 PF14362.6 KIK59834.1 - 2.9 7.2 8.0 4 6.7 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NYD-SP28_assoc PF14775.6 KIK59834.1 - 4.2 7.6 14.8 2.5 8.3 1.1 3.6 3 1 0 3 3 3 0 Sperm tail C-terminal domain Prominin PF05478.11 KIK59834.1 - 4.3 5.2 8.5 5.6 4.8 8.5 1.1 1 0 0 1 1 1 0 Prominin Phage_Mu_Gam PF07352.12 KIK59834.1 - 5 7.0 8.4 0.25 11.2 2.0 2.1 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein TerB_C PF15615.6 KIK59834.1 - 6.6 7.0 13.5 0.32 11.3 6.7 2.3 1 1 2 3 3 3 0 TerB-C domain DUF1043 PF06295.12 KIK59834.1 - 8.9 6.3 10.8 5.6 7.0 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Nt_Gln_amidase PF09764.9 KIK59835.1 - 2e-59 200.3 0.4 2.4e-59 200.1 0.4 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase UQ_con PF00179.26 KIK59840.1 - 8.6e-42 142.1 0.2 9.7e-42 141.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK59840.1 - 2.8e-05 23.8 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIK59840.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KIK59840.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 RWD domain TAFII55_N PF04658.13 KIK59841.1 - 2.3e-54 183.5 0.2 2.3e-54 183.5 0.2 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF4032 PF13224.6 KIK59841.1 - 0.004 17.0 0.6 0.0086 16.0 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) PKcGMP_CC PF16808.5 KIK59841.1 - 0.41 10.5 9.7 0.2 11.5 0.9 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SDA1 PF05285.12 KIK59841.1 - 0.77 9.1 25.8 1.1 8.6 25.8 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIK59841.1 - 1.2 8.4 24.7 0.024 14.0 17.9 1.7 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KIK59841.1 - 4.8 5.3 27.8 6.7 4.8 27.8 1.2 1 0 0 1 1 1 0 Nop14-like family Protoglobin PF11563.8 KIK59842.1 - 9.4e-38 129.6 0.0 1.1e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Protoglobin SPRY PF00622.28 KIK59843.1 - 1.2e-09 38.3 0.0 1.2e-06 28.6 0.0 3.1 3 0 0 3 3 3 2 SPRY domain MMS1_N PF10433.9 KIK59844.1 - 2.2e-54 184.9 0.0 5.1e-54 183.7 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIK59844.1 - 1.4e-49 169.2 0.0 1e-48 166.3 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region UPF0139 PF03669.13 KIK59847.1 - 0.037 13.9 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) PhoD PF09423.10 KIK59848.1 - 0.05 12.6 0.0 0.41 9.6 0.0 2.3 3 0 0 3 3 3 0 PhoD-like phosphatase NMU PF02070.15 KIK59848.1 - 5 7.1 5.7 8.8 6.3 2.1 2.8 2 0 0 2 2 2 0 Neuromedin U CAP_N PF01213.19 KIK59849.1 - 2e-100 336.4 0.4 2.6e-100 336.0 0.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KIK59849.1 - 3.9e-57 192.3 4.4 5.8e-57 191.7 4.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KIK59849.1 - 0.029 14.1 4.7 0.084 12.6 4.7 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C RF-1 PF00472.20 KIK59850.1 - 4.9e-24 84.5 3.7 4.9e-24 84.5 3.7 1.7 1 1 1 2 2 2 1 RF-1 domain Complex1_LYR_2 PF13233.6 KIK59850.1 - 0.65 10.8 6.0 0.096 13.5 0.5 2.3 2 1 0 2 2 2 0 Complex1_LYR-like Linker_histone PF00538.19 KIK59851.1 - 3.2e-23 81.9 0.5 1e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family Cbl_N3 PF02762.14 KIK59851.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain zf-MYND PF01753.18 KIK59852.1 - 1.1e-08 35.0 13.8 2.1e-08 34.1 13.8 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIK59852.1 - 5.3 7.2 11.5 34 4.6 11.5 2.2 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 EI24 PF07264.11 KIK59853.1 - 1.3e-39 136.3 9.9 1.7e-39 135.9 9.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) tRNA_int_endo PF01974.17 KIK59854.1 - 1.8e-14 53.5 0.0 3.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Lipase_GDSL_2 PF13472.6 KIK59855.1 - 4.2e-24 85.9 0.3 6.9e-24 85.2 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK59855.1 - 5.1e-12 46.2 0.0 7.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.20 KIK59856.1 - 2.6e-13 50.4 0.0 5.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF1666 PF07891.12 KIK59857.1 - 0.056 13.1 0.1 0.069 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) PEX11 PF05648.14 KIK59857.1 - 0.074 12.5 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Tyrosinase PF00264.20 KIK59858.1 - 8.7e-57 192.9 2.0 1.8e-56 191.9 0.1 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIK59858.1 - 2.7e-37 128.2 0.0 4.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF2433 PF10360.9 KIK59859.1 - 0.24 11.5 2.3 0.31 11.1 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2433) Yuri_gagarin PF15934.5 KIK59859.1 - 0.59 9.9 9.5 0.26 11.1 5.3 2.2 1 1 1 2 2 2 0 Yuri gagarin Exonuc_VII_L PF02601.15 KIK59859.1 - 0.72 9.4 17.1 0.1 12.1 5.8 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 KIK59859.1 - 1.2 8.2 18.0 3.3 6.7 3.1 3.1 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RPW8 PF05659.11 KIK59859.1 - 1.4 8.6 6.7 4.7 6.9 0.3 3.4 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 COG2 PF06148.11 KIK59859.1 - 1.5 8.9 17.2 5 7.2 0.9 4.2 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KIK59859.1 - 2.8 6.8 25.6 0.86 8.4 4.9 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF615 PF04751.14 KIK59859.1 - 2.8 7.9 14.4 1.6 8.7 3.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF615) Matrilin_ccoil PF10393.9 KIK59859.1 - 2.9 7.8 5.2 17 5.3 0.2 4.0 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin T7SS_ESX_EspC PF10824.8 KIK59859.1 - 3 8.4 11.2 12 6.5 0.9 3.4 3 2 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Cpn60_TCP1 PF00118.24 KIK59860.1 - 1.2e-145 485.9 12.4 1.4e-145 485.7 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KIK59860.1 - 0.00026 20.6 0.2 0.0007 19.1 0.1 1.8 2 1 0 2 2 2 1 Telomere recombination DUF2326 PF10088.9 KIK59860.1 - 0.087 12.6 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) ECH_1 PF00378.20 KIK59861.1 - 5.5e-26 91.4 0.0 6.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK59861.1 - 3.9e-17 62.7 0.0 4.5e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AA_permease PF00324.21 KIK59862.1 - 9.2e-127 423.5 37.7 1.1e-126 423.2 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK59862.1 - 5.6e-33 114.4 42.3 7.3e-33 114.0 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease 2-oxoacid_dh PF00198.23 KIK59863.1 - 2e-48 164.9 0.0 7.4e-48 163.0 0.0 1.9 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK59863.1 - 1.3e-19 69.8 0.2 2.2e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIK59863.1 - 1.9e-14 53.7 0.0 3.9e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIK59863.1 - 0.00012 21.8 0.2 0.0016 18.3 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KIK59863.1 - 0.00041 21.0 0.3 0.0043 17.7 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 KIK59863.1 - 0.0041 16.3 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion CLTH PF10607.9 KIK59865.1 - 1.7e-20 73.4 0.0 3.7e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KIK59865.1 - 4.5e-07 29.8 0.1 8.9e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KIK59865.1 - 0.00015 21.3 0.3 0.00034 20.1 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 KIK59865.1 - 0.0062 16.4 0.5 0.013 15.4 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK59865.1 - 0.011 16.0 0.3 0.021 15.1 0.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KIK59865.1 - 0.017 15.1 0.3 0.034 14.1 0.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK59865.1 - 0.023 14.6 0.3 0.049 13.5 0.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIK59865.1 - 0.047 13.5 1.1 0.047 13.5 1.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KIK59865.1 - 0.072 13.0 0.7 0.13 12.1 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BORCS6 PF10157.9 KIK59865.1 - 0.091 13.0 0.4 0.2 11.9 0.4 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Pellino PF04710.14 KIK59865.1 - 0.1 11.2 0.2 0.15 10.7 0.2 1.2 1 0 0 1 1 1 0 Pellino DASH_Dad2 PF08654.10 KIK59865.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 zf-C3HC4_4 PF15227.6 KIK59865.1 - 0.12 12.5 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MDM10 PF12519.8 KIK59865.1 - 0.13 11.1 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CRM1_C PF08767.11 KIK59866.1 - 1.6e-133 444.8 0.3 1.6e-133 444.8 0.3 3.4 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KIK59866.1 - 1.9e-41 141.6 8.4 2.4e-40 138.0 8.2 3.1 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIK59866.1 - 3.9e-34 116.1 3.7 1e-33 114.8 3.7 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIK59866.1 - 1.6e-30 105.0 1.2 1.6e-30 105.0 1.2 2.8 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIK59866.1 - 1.4e-18 66.1 2.4 1.4e-18 66.1 2.4 2.0 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIK59866.1 - 4.7e-13 48.8 0.0 2.2e-12 46.7 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KIK59866.1 - 0.03 14.3 0.4 0.44 10.4 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) ABC_transp_aux PF09822.9 KIK59866.1 - 0.055 12.9 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Vac14_Fab1_bd PF12755.7 KIK59866.1 - 0.24 12.0 1.2 7.4 7.2 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Pre-PUA PF17832.1 KIK59867.1 - 1.5e-24 86.4 0.1 2.4e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KIK59867.1 - 1.4e-13 50.6 0.0 2.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 PUA domain TPR_1 PF00515.28 KIK59869.1 - 7.3e-28 95.2 2.0 2.4e-07 30.3 0.1 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK59869.1 - 6e-27 91.6 7.0 0.00027 20.8 0.1 9.8 10 0 0 10 10 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK59869.1 - 1e-21 76.9 10.7 2.9e-14 53.0 1.5 5.3 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIK59869.1 - 1.4e-19 68.6 1.4 0.036 14.3 0.0 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK59869.1 - 4.8e-19 68.6 5.2 6.8e-06 26.5 0.0 7.0 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIK59869.1 - 7.7e-17 61.7 14.1 1e-05 26.1 0.0 7.6 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIK59869.1 - 1.2e-16 60.1 2.4 0.018 14.7 0.0 8.0 7 2 2 9 9 9 4 TPR repeat TPR_14 PF13428.6 KIK59869.1 - 8e-16 57.4 11.1 0.086 13.7 0.0 9.9 4 1 6 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK59869.1 - 1.6e-15 56.2 0.8 0.024 15.0 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK59869.1 - 1.9e-14 53.7 8.0 0.00027 21.2 0.0 7.4 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 KIK59869.1 - 1.9e-08 34.4 10.4 1.9 9.3 0.0 8.7 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK59869.1 - 2.1e-07 31.0 6.9 0.53 10.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK59869.1 - 2e-06 27.4 5.7 0.54 10.4 0.0 7.0 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK59869.1 - 0.0007 18.9 3.3 0.3 10.3 0.4 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat PPTA PF01239.22 KIK59869.1 - 0.003 17.3 0.1 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.6 KIK59869.1 - 0.11 12.4 4.5 47 4.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 KIK59869.1 - 0.12 11.3 0.1 6.7 5.6 0.0 2.5 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 KIK59869.1 - 0.14 11.9 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KIK59869.1 - 1.7 9.5 9.6 49 5.0 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Rep_3 PF01051.21 KIK59870.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Initiator Replication protein MFS_1 PF07690.16 KIK59871.1 - 4.5e-41 140.9 27.4 4.5e-41 140.9 27.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK59871.1 - 3.5e-09 36.0 14.4 3.5e-09 36.0 14.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK59871.1 - 1.8e-05 23.4 4.0 3.1e-05 22.6 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 KIK59871.1 - 0.0095 14.6 2.0 0.0095 14.6 2.0 2.7 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_3 PF05977.13 KIK59871.1 - 0.045 12.1 5.1 0.093 11.1 5.1 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Aldo_ket_red PF00248.21 KIK59872.1 - 6.8e-49 166.6 0.0 7.8e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTU PF02338.19 KIK59873.1 - 1.4e-23 83.8 0.0 4e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KIK59873.1 - 1.2e-05 24.9 0.0 0.057 12.9 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain Adaptin_N PF01602.20 KIK59874.1 - 7e-123 410.9 3.1 9.3e-123 410.5 3.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK59874.1 - 2e-55 187.2 1.6 5.3e-52 176.1 0.1 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK59874.1 - 1.4e-13 51.1 10.4 3.1e-07 30.7 0.7 5.3 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.22 KIK59874.1 - 9.4e-10 37.9 4.4 0.064 13.5 0.0 6.4 8 0 0 8 8 8 3 HEAT repeat Arm PF00514.23 KIK59874.1 - 3.8e-05 23.6 1.0 0.19 11.8 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 KIK59874.1 - 0.0012 18.2 0.1 0.29 10.3 0.1 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KIK59874.1 - 0.0013 19.1 4.5 10 6.7 0.1 6.0 7 0 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 KIK59874.1 - 0.0096 15.5 0.0 0.18 11.3 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal U3snoRNP10 PF12397.8 KIK59874.1 - 0.035 14.5 0.0 0.21 12.0 0.0 2.3 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Cu_bind_like PF02298.17 KIK59875.1 - 0.00011 22.1 0.1 0.00026 20.9 0.1 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KIK59875.1 - 0.068 13.6 0.7 0.22 12.0 0.7 1.8 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family RAP1 PF07218.11 KIK59875.1 - 7.2 4.8 13.9 10 4.2 13.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pyr_redox_2 PF07992.14 KIK59878.1 - 6.1e-11 42.1 0.0 3.1e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 KIK59878.1 - 0.0027 17.0 0.1 0.005 16.1 0.1 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.6 KIK59878.1 - 0.0072 16.3 0.3 4.6 7.2 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KIK59878.1 - 0.021 14.4 0.6 2.5 7.6 0.2 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase PI-PLC-X PF00388.19 KIK59879.1 - 6e-48 162.1 0.0 1.5e-47 160.8 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIK59879.1 - 4.1e-41 139.9 0.0 1.1e-40 138.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIK59879.1 - 3.3e-05 24.1 0.0 0.23 11.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_10 PF14788.6 KIK59879.1 - 0.0002 21.2 0.1 0.00056 19.7 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KIK59879.1 - 0.061 13.8 1.1 0.24 11.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair PH_14 PF17787.1 KIK59879.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain SPX PF03105.19 KIK59879.1 - 0.87 9.4 10.4 0.04 13.9 1.1 2.2 2 0 0 2 2 2 0 SPX domain RNase_PH PF01138.21 KIK59880.1 - 4.6e-32 111.3 0.1 8.8e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK59880.1 - 8.6e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 B12-binding_2 PF02607.17 KIK59880.1 - 0.06 13.8 0.0 0.084 13.3 0.0 1.4 1 1 0 1 1 1 0 B12 binding domain MSC PF09402.10 KIK59881.1 - 4e-90 302.7 0.0 5.6e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KIK59881.1 - 1.1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain UEV PF05743.13 KIK59882.1 - 9.2e-24 83.6 0.0 1.6e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KIK59882.1 - 9.3e-18 63.9 0.0 2.4e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Vps23 core domain Fib_alpha PF08702.10 KIK59882.1 - 0.33 11.1 2.1 3.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TEA PF01285.18 KIK59883.1 - 6.6e-15 54.9 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain DUF2457 PF10446.9 KIK59883.1 - 0.26 10.4 7.0 0.35 9.9 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOC3p PF07540.11 KIK59884.1 - 1.3e-31 108.9 0.6 3e-31 107.7 0.1 2.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KIK59884.1 - 2.4e-18 66.8 0.3 9.8e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family DUF4477 PF14780.6 KIK59885.1 - 1.7e-05 24.5 0.3 1.9e-05 24.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) DUF4477 PF14780.6 KIK59886.1 - 0.002 17.8 0.9 0.0028 17.3 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) CLASP_N PF12348.8 KIK59888.1 - 5.2e-27 94.9 0.4 2.3e-07 30.6 0.0 4.8 4 1 0 4 4 4 4 CLASP N terminal Cnd1 PF12717.7 KIK59888.1 - 2.3e-11 44.0 0.2 0.044 13.8 0.0 7.1 6 2 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK59888.1 - 1.2e-08 34.5 13.3 0.1 12.9 0.0 9.9 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 KIK59888.1 - 2.8e-07 30.8 13.6 3.1 8.2 0.0 8.9 7 1 2 9 9 9 2 HEAT repeats Nipped-B_C PF12830.7 KIK59888.1 - 0.0019 18.2 0.1 1.8 8.5 0.0 3.0 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 KIK59888.1 - 0.022 15.2 6.8 7.5 7.2 0.0 6.1 5 1 2 7 7 7 0 HEAT-like repeat TIP120 PF08623.10 KIK59888.1 - 0.024 14.4 0.0 14 5.4 0.0 4.7 6 0 0 6 6 6 0 TATA-binding protein interacting (TIP20) MMS19_N PF14500.6 KIK59888.1 - 0.065 12.8 9.8 5.3 6.5 0.3 6.2 5 2 3 8 8 8 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 KIK59888.1 - 0.099 12.8 0.8 6.2 7.1 0.0 3.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 VHS PF00790.19 KIK59888.1 - 0.1 12.4 0.4 13 5.6 0.0 3.3 3 0 0 3 3 3 0 VHS domain TAN PF11640.8 KIK59888.1 - 0.14 12.3 8.1 0.4 10.8 0.0 4.6 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair Acyltransferase PF01553.21 KIK59889.1 - 2.1e-13 50.1 0.0 3.3e-06 26.7 0.0 2.8 3 0 0 3 3 3 2 Acyltransferase GPDPase_memb PF10110.9 KIK59889.1 - 0.078 11.7 3.1 0.13 11.1 3.1 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Peptidase_M24 PF00557.24 KIK59891.1 - 1.1e-52 178.8 0.0 1.4e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KIK59891.1 - 1.8e-15 57.0 5.4 3.6e-15 56.0 5.4 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KIK59891.1 - 0.023 14.8 5.7 0.049 13.7 5.7 1.6 1 0 0 1 1 1 0 MYND finger RecR PF02132.15 KIK59891.1 - 0.36 10.4 2.7 1.1 8.9 2.7 1.8 1 0 0 1 1 1 0 RecR protein zf-HIT PF04438.16 KIK59891.1 - 0.62 10.0 6.5 1.1 9.2 6.5 1.5 1 0 0 1 1 1 0 HIT zinc finger Peptidase_M24 PF00557.24 KIK59893.1 - 1.9e-52 178.0 0.0 2.6e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 IF-2B PF01008.17 KIK59895.1 - 7.1e-56 189.5 0.0 1.4e-55 188.5 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family HisKA PF00512.25 KIK59895.1 - 0.0044 17.0 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PGBA_N PF15436.6 KIK59895.1 - 0.091 12.4 0.1 18 4.8 0.0 2.7 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA N-terminal PALP PF00291.25 KIK59895.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-RING_6 PF14835.6 KIK59896.1 - 1.2 9.1 8.2 0.21 11.5 3.4 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Cyclin_N PF00134.23 KIK59897.1 - 7e-13 48.4 0.3 1.3e-12 47.6 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KIK59897.1 - 0.00031 20.7 0.0 0.00098 19.1 0.0 1.7 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KIK59897.1 - 0.0018 18.3 0.2 0.75 9.9 0.1 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain UNC-79 PF14776.6 KIK59899.1 - 0.031 13.0 5.0 0.038 12.8 5.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Ribosomal_S27e PF01667.17 KIK59899.1 - 0.35 10.6 3.7 0.38 10.5 1.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 Ribosomal_S21 PF01165.20 KIK59900.1 - 1.2e-13 50.5 0.7 2.2e-13 49.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 RWD PF05773.22 KIK59901.1 - 3.8e-17 62.7 0.4 9.9e-17 61.3 0.4 1.7 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KIK59901.1 - 2.5e-06 27.9 11.8 6.9e-06 26.5 11.8 1.8 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 ketoacyl-synt PF00109.26 KIK59901.1 - 0.13 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Spc7_C2 PF15577.6 KIK59901.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Spc7_C2 Peptidase_C37 PF05416.12 KIK59901.1 - 3.7 6.0 7.7 4.4 5.7 7.7 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf-CCCH_2 PF14608.6 KIK59902.1 - 0.011 16.2 0.3 0.025 15.0 0.3 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CSTF2_hinge PF14327.6 KIK59902.1 - 0.059 13.8 4.1 5.2 7.6 2.0 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 zf-CCCH PF00642.24 KIK59902.1 - 0.14 12.1 3.9 1.2 9.2 2.3 2.6 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK59902.1 - 1.7 8.8 10.7 0.21 11.7 0.5 2.8 3 0 0 3 3 3 0 Zinc finger domain Antimicrobial_5 PF08026.11 KIK59903.1 - 0.54 10.4 9.6 0.31 11.2 3.4 3.9 2 0 0 2 2 2 0 Bee antimicrobial peptide TSC22 PF01166.18 KIK59904.1 - 0.024 14.9 0.5 0.051 13.9 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 KIK59904.1 - 9.3 6.1 7.0 0.64 9.8 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator adh_short PF00106.25 KIK59905.1 - 5.1e-49 166.4 1.2 7e-49 165.9 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK59905.1 - 2.5e-31 109.0 2.4 3.3e-31 108.7 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK59905.1 - 4.3e-13 49.6 0.8 5.5e-13 49.2 0.8 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK59905.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Helicase_RecD PF05127.14 KIK59905.1 - 0.0046 16.8 0.1 0.0088 15.9 0.0 1.4 2 0 0 2 2 2 1 Helicase SET PF00856.28 KIK59906.1 - 0.00045 20.6 0.0 0.00088 19.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Disaggr_repeat PF06848.11 KIK59906.1 - 0.055 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Disaggregatase related repeat Sec61_beta PF03911.16 KIK59907.1 - 0.089 12.8 0.4 0.089 12.8 0.4 2.1 2 0 0 2 2 2 0 Sec61beta family PAP2 PF01569.21 KIK59909.1 - 3.9e-13 49.4 4.5 5.6e-13 48.8 4.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIK59909.1 - 0.00081 19.5 0.5 0.01 16.0 0.0 2.1 2 0 0 2 2 2 1 Divergent PAP2 family 7TMR-DISM_7TM PF07695.11 KIK59909.1 - 0.023 14.6 3.2 1.4 8.8 0.0 2.5 2 1 0 2 2 2 0 7TM diverse intracellular signalling PgaD PF13994.6 KIK59909.1 - 0.09 12.8 0.8 0.22 11.5 0.8 1.6 1 0 0 1 1 1 0 PgaD-like protein DnaJ PF00226.31 KIK59910.1 - 1.7e-22 79.3 2.4 6e-22 77.5 2.4 2.0 1 0 0 1 1 1 1 DnaJ domain GET2 PF08690.10 KIK59910.1 - 0.86 9.2 4.4 2.3 7.8 4.4 1.7 1 0 0 1 1 1 0 GET complex subunit GET2 RAI16-like PF10257.9 KIK59911.1 - 4.1e-68 229.9 0.1 6.2e-68 229.3 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TerB_C PF15615.6 KIK59911.1 - 3 8.1 8.3 8.8 6.6 0.0 3.1 3 0 0 3 3 3 0 TerB-C domain KLRAQ PF10205.9 KIK59912.1 - 0.89 9.8 13.3 0.69 10.2 5.2 3.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 KIK59912.1 - 2.7 6.5 8.8 5 5.6 1.2 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Fez1 PF06818.15 KIK59912.1 - 5.2 7.5 24.8 0.12 12.8 4.2 3.0 2 1 0 3 3 3 0 Fez1 DMPK_coil PF08826.10 KIK59912.1 - 6.5 7.0 26.7 0.91 9.7 2.4 4.6 2 2 2 4 4 4 0 DMPK coiled coil domain like Torus PF16131.5 KIK59913.1 - 9.3e-41 138.9 2.2 1.7e-40 138.1 2.2 1.4 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.6 KIK59913.1 - 1.3e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KIK59913.1 - 0.00053 19.8 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KIK59913.1 - 0.16 12.1 5.4 0.3 11.2 5.4 1.5 1 0 0 1 1 1 0 Zinc finger domain Glucan_synthase PF02364.15 KIK59915.1 - 0 1322.9 0.0 0 1322.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIK59915.1 - 4.3e-41 140.3 0.0 1.2e-40 138.8 0.0 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Pro-kuma_activ PF09286.11 KIK59918.1 - 4.7e-35 121.0 0.1 7.7e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK59918.1 - 7.2e-06 25.5 0.1 1.2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family SpoIIE PF07228.12 KIK59919.1 - 7e-09 35.9 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIK59919.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C Kinesin PF00225.23 KIK59920.1 - 1.3e-65 221.5 0.0 2.6e-65 220.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK59920.1 - 1.1e-09 38.3 0.0 2.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TPR_11 PF13414.6 KIK59920.1 - 0.0076 15.9 0.3 0.016 14.9 0.3 1.5 1 0 0 1 1 1 1 TPR repeat CRAL_TRIO PF00650.20 KIK59921.1 - 2.8e-31 108.4 0.2 4.9e-31 107.6 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK59921.1 - 0.00097 19.3 0.6 0.0026 17.9 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain zinc_ribbon_4 PF13717.6 KIK59921.1 - 0.01 15.7 0.2 0.026 14.4 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain RIG-I_C-RD PF11648.8 KIK59921.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of RIG-I zinc_ribbon_5 PF13719.6 KIK59921.1 - 0.23 11.2 0.2 0.23 11.2 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon domain DUF2457 PF10446.9 KIK59923.1 - 0.47 9.5 7.4 0.57 9.3 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CRAL_TRIO PF00650.20 KIK59924.1 - 2e-06 27.6 0.0 3.8e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain TILa PF12714.7 KIK59927.1 - 0.044 13.7 2.6 0.068 13.1 2.6 1.3 1 0 0 1 1 1 0 TILa domain CRAL_TRIO PF00650.20 KIK59928.1 - 1e-28 100.1 0.4 8.5e-23 80.8 0.0 2.5 2 1 1 3 3 3 2 CRAL/TRIO domain DUF2457 PF10446.9 KIK59930.1 - 0.091 11.9 1.3 0.12 11.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CRAL_TRIO PF00650.20 KIK59931.1 - 3.4e-35 121.1 0.0 4.4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK59936.1 - 2.2e-30 105.5 0.1 3.8e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK59938.1 - 1.7e-29 102.6 0.1 3.6e-29 101.5 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK59938.1 - 0.049 13.8 0.4 0.15 12.3 0.4 1.9 1 1 0 1 1 1 0 CRAL/TRIO, N-terminal domain TamB PF04357.13 KIK59941.1 - 0.65 9.2 1.8 3.6 6.7 0.5 2.0 1 1 1 2 2 2 0 TamB, inner membrane protein subunit of TAM complex CRAL_TRIO PF00650.20 KIK59942.1 - 3.1e-32 111.5 0.3 4.8e-32 110.9 0.1 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain DUF2457 PF10446.9 KIK59944.1 - 0.0011 18.2 0.4 0.0014 17.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CRAL_TRIO PF00650.20 KIK59945.1 - 4.2e-32 111.1 0.2 9.1e-32 110.0 0.1 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK59945.1 - 7.8e-08 32.4 0.7 1.8e-07 31.2 0.7 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain YtkA PF13115.6 KIK59946.1 - 0.13 12.9 0.3 12 6.6 0.0 2.3 2 0 0 2 2 2 0 YtkA-like CRAL_TRIO PF00650.20 KIK59947.1 - 1.1e-17 64.2 0.0 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 CRAL/TRIO domain Ribosomal_S21 PF01165.20 KIK59947.1 - 0.2 11.4 0.0 5.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S21 KASH_CCD PF14662.6 KIK59952.1 - 0.022 14.6 1.9 0.022 14.6 1.9 2.4 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DNA_mis_repair PF01119.19 KIK59952.1 - 0.085 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain LRRFIP PF09738.9 KIK59952.1 - 0.17 11.3 8.0 0.28 10.6 8.0 1.3 1 0 0 1 1 1 0 LRRFIP family Filament PF00038.21 KIK59952.1 - 0.27 10.8 6.5 0.52 9.8 6.5 1.4 1 0 0 1 1 1 0 Intermediate filament protein HTH_Tnp_Tc3_2 PF01498.18 KIK59954.1 - 0.04 14.2 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 Transposase Toxin_7 PF05980.12 KIK59955.1 - 0.11 12.8 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Toxin 7 DEAD PF00270.29 KIK59958.1 - 3.9e-11 43.0 0.0 4.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK59958.1 - 4.9e-05 23.4 0.0 5.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KIK59958.1 - 0.0057 15.5 0.1 0.14 10.9 0.0 2.0 2 0 0 2 2 2 2 Type IV secretory system Conjugative DNA transfer AAA_30 PF13604.6 KIK59958.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain CRAL_TRIO PF00650.20 KIK59959.1 - 1.5e-07 31.3 0.5 3.3e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain DUF667 PF05018.13 KIK59960.1 - 0.017 14.8 0.0 0.021 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF667) gag_pre-integrs PF13976.6 KIK59962.1 - 1.2e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain CRAL_TRIO PF00650.20 KIK59963.1 - 1.3e-07 31.5 0.1 2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK59964.1 - 4.9e-16 58.8 0.0 5.8e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain MOZART1 PF12554.8 KIK59965.1 - 0.074 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated KASH_CCD PF14662.6 KIK59969.1 - 0.0053 16.6 1.5 0.0053 16.6 1.5 2.4 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH BBS1 PF14779.6 KIK59969.1 - 0.034 13.6 1.2 0.072 12.5 1.2 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Phage_GP20 PF06810.11 KIK59969.1 - 0.18 11.6 3.2 0.19 11.5 0.5 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KIK59969.1 - 0.33 11.0 15.4 0.73 9.9 4.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KIK59969.1 - 0.35 10.9 3.3 4.1 7.5 0.4 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FapA PF03961.13 KIK59969.1 - 1.1 7.8 2.9 1.6 7.2 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Wtap PF17098.5 KIK59969.1 - 4.8 7.1 11.7 9.3 6.2 10.1 2.3 2 1 0 2 2 2 0 WTAP/Mum2p family Ank_2 PF12796.7 KIK59970.1 - 1e-14 54.8 1.0 1.5e-09 38.3 0.1 3.4 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK59970.1 - 6.2e-13 49.0 1.4 4.6e-07 30.2 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK59970.1 - 3.7e-10 39.1 3.8 0.037 14.6 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KIK59970.1 - 3.9e-09 36.6 0.2 9.3e-05 22.6 0.2 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK59970.1 - 2e-06 28.0 4.2 0.0053 17.1 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat CRAL_TRIO PF00650.20 KIK59972.1 - 6.3e-25 87.8 0.1 4.3e-23 81.8 0.1 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KIK59972.1 - 0.0031 17.7 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PBECR3 PF18812.1 KIK59972.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 CRAL_TRIO PF00650.20 KIK59974.1 - 7.3e-28 97.3 0.7 2.6e-22 79.2 0.0 2.4 2 1 1 3 3 3 2 CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK59978.1 - 4e-29 101.4 0.0 8.4e-29 100.3 0.0 1.5 1 1 1 2 2 2 1 CRAL/TRIO domain YtkA PF13115.6 KIK59980.1 - 0.2 12.3 0.2 19 5.9 0.0 2.3 2 0 0 2 2 2 0 YtkA-like CRAL_TRIO PF00650.20 KIK59981.1 - 7.8e-37 126.4 0.2 2.7e-36 124.7 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain Phosducin PF02114.16 KIK59982.1 - 3.1e-17 62.4 1.0 2.2e-08 33.3 0.6 3.2 2 1 0 2 2 2 2 Phosducin DUF4818 PF16089.5 KIK59983.1 - 5.2 7.6 13.5 0.82 10.1 7.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4818) GDI PF00996.18 KIK59984.1 - 7.4e-48 163.1 0.0 1.6e-47 162.0 0.0 1.5 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KIK59984.1 - 5.5e-05 23.3 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glyco_hydro_43 PF04616.14 KIK59985.1 - 1.8e-25 89.8 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF4234 PF14018.6 KIK59986.1 - 0.044 13.9 16.0 0.047 13.8 1.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Med13_C PF06333.12 KIK59991.1 - 7.6e-63 212.8 8.7 1.5e-62 211.8 8.7 1.4 1 1 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain SOG2 PF10428.9 KIK59992.1 - 0.034 13.4 12.3 0.31 10.2 2.9 2.5 2 0 0 2 2 2 0 RAM signalling pathway protein CDC45 PF02724.14 KIK59992.1 - 0.037 12.3 3.1 0.063 11.6 3.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Med13_N PF11597.8 KIK59993.1 - 3.2e-14 53.1 0.3 3.7e-13 49.6 0.3 2.2 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal NACHT PF05729.12 KIK59994.1 - 2.2e-09 37.5 0.0 6.1e-08 32.7 0.0 2.7 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK59994.1 - 2.8e-05 24.6 0.0 9.9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK59994.1 - 0.0022 18.4 0.0 0.057 13.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KIK59994.1 - 0.021 15.3 0.0 0.76 10.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIK59994.1 - 0.037 13.4 0.0 1 8.7 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein ATPase_2 PF01637.18 KIK59994.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK59994.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KIK59994.1 - 0.11 12.8 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK59994.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Herpes_UL73 PF03554.13 KIK59995.1 - 0.023 14.7 1.9 0.06 13.4 1.9 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein NACHT PF05729.12 KIK59996.1 - 5e-06 26.5 0.0 6.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK59996.1 - 0.00011 22.7 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK59996.1 - 0.0034 17.3 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ResIII PF04851.15 KIK59996.1 - 0.0089 16.1 0.0 4.2 7.3 0.0 2.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit TsaE PF02367.17 KIK59996.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIK59996.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK59996.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KIK59996.1 - 0.04 13.0 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KIK59996.1 - 0.052 13.3 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK59996.1 - 0.053 13.8 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK59996.1 - 0.09 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase PF06745.13 KIK59996.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 KIK59996.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 KIK59996.1 - 0.19 11.5 0.1 0.37 10.6 0.1 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 KIK59997.1 - 1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK59997.1 - 6.3e-05 23.4 0.0 7.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK59997.1 - 0.00082 19.3 0.0 0.001 19.0 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK59997.1 - 0.0015 17.7 0.2 0.0021 17.2 0.2 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK59997.1 - 0.0022 18.3 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KIK59997.1 - 0.0023 18.0 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KIK59997.1 - 0.003 17.8 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK59997.1 - 0.0031 17.2 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK59997.1 - 0.0091 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KIK59997.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KIK59997.1 - 0.021 14.3 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.20 KIK59997.1 - 0.025 14.5 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK59997.1 - 0.03 13.5 0.0 0.063 12.5 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KIK59997.1 - 0.041 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK59997.1 - 0.078 13.5 0.0 0.094 13.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KIK59997.1 - 0.081 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIK59997.1 - 0.086 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KIK59997.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK59997.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 KIK59997.1 - 0.18 11.4 0.6 0.34 10.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 KIK59997.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 KIK59998.1 - 0.00094 19.1 0.0 0.0021 18.0 0.0 1.6 1 1 1 2 2 2 1 NACHT domain Methyltransf_2 PF00891.18 KIK59999.1 - 1e-22 80.5 0.6 7.4e-22 77.7 0.6 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KIK59999.1 - 0.0055 17.4 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK59999.1 - 0.0085 16.8 0.0 0.081 13.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KIK59999.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CRAL_TRIO PF00650.20 KIK60005.1 - 6.5e-36 123.4 0.0 1.2e-35 122.5 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK60005.1 - 1.7e-10 40.9 0.7 4.3e-10 39.6 0.7 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain APH PF01636.23 KIK60006.1 - 5.7e-11 42.8 0.1 5.3e-10 39.6 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIK60006.1 - 0.019 13.9 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) gag_pre-integrs PF13976.6 KIK60008.1 - 5.6e-08 32.5 0.0 7.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain Ribosomal_L5 PF00281.19 KIK60009.1 - 0.0023 18.2 0.1 0.0032 17.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L5 Linker_histone PF00538.19 KIK60009.1 - 0.061 13.7 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 linker histone H1 and H5 family Complex1_51K PF01512.17 KIK60010.1 - 1.7e-47 161.1 0.0 2.6e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KIK60010.1 - 7.3e-31 106.1 1.1 1.3e-30 105.3 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KIK60010.1 - 5.5e-08 32.6 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 KIK60010.1 - 0.13 12.3 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DAO PF01266.24 KIK60011.1 - 4.5e-26 92.3 0.0 5.2e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK60011.1 - 3.2e-05 24.1 0.1 7.2e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIK60011.1 - 0.00024 21.5 0.0 0.0005 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIK60011.1 - 0.00061 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK60011.1 - 0.001 19.6 0.0 0.0039 17.7 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK60011.1 - 0.0013 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK60011.1 - 0.0028 17.0 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK60011.1 - 0.004 16.3 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIK60011.1 - 0.0047 16.2 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIK60011.1 - 0.028 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KIK60011.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIK60011.1 - 0.055 12.2 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein IlvN PF07991.12 KIK60011.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 KIK60011.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ACT_7 PF13840.6 KIK60012.1 - 0.07 12.9 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 ACT domain Col_cuticle_N PF01484.17 KIK60013.1 - 3.5 7.7 6.0 9.4 6.4 1.6 2.1 1 1 1 2 2 2 0 Nematode cuticle collagen N-terminal domain Acetyltransf_3 PF13302.7 KIK60014.1 - 3.3e-18 66.7 0.0 4.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK60014.1 - 7.6e-11 42.3 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIK60014.1 - 3.5e-09 37.0 0.0 4.1e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK60014.1 - 8.6e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK60014.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK60014.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF3658 PF12395.8 KIK60015.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF3328 PF11807.8 KIK60016.1 - 1.1e-33 116.9 1.1 1.2e-33 116.8 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tht1 PF04163.12 KIK60017.1 - 1.8e-05 23.7 0.2 2e-05 23.6 0.2 1.0 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Dicty_CAR PF05462.11 KIK60023.1 - 0.0011 18.2 2.3 0.0011 18.1 1.5 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor ODV-E18 PF10717.9 KIK60023.1 - 0.083 12.8 0.2 0.083 12.8 0.2 2.5 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 ACOX PF01756.19 KIK60024.1 - 1.1e-35 122.9 0.0 2.2e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KIK60024.1 - 6.3e-17 62.3 0.0 1.3e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KIK60024.1 - 1.3e-07 31.7 0.0 3.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KIK60024.1 - 0.018 15.3 0.2 0.04 14.1 0.2 1.7 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AAA_18 PF13238.6 KIK60025.1 - 5.9e-07 30.1 0.0 8.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK60025.1 - 6.6e-06 26.3 0.0 9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KIK60025.1 - 0.0004 20.3 0.0 0.00078 19.3 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KIK60025.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK60025.1 - 0.082 13.2 0.0 0.29 11.5 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK60026.1 - 0.019 15.4 0.0 0.021 15.2 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK60026.1 - 0.035 13.3 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KIK60026.1 - 0.091 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 KIK60026.1 - 0.13 11.8 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KIK60026.1 - 0.16 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain BetaGal_dom4_5 PF13364.6 KIK60027.1 - 9.6e-05 22.9 0.4 0.27 11.8 0.0 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Bac_rhamnosid_N PF08531.10 KIK60027.1 - 9.7e-05 22.3 0.6 0.0061 16.4 0.0 3.1 3 0 0 3 3 3 1 Alpha-L-rhamnosidase N-terminal domain PA14 PF07691.12 KIK60027.1 - 0.00069 19.4 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 PA14 domain OTCace PF00185.24 KIK60028.1 - 2.8e-43 147.7 0.0 4e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KIK60028.1 - 3.2e-43 147.3 0.0 4.8e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Bacteroid_pep PF14406.6 KIK60038.1 - 0.17 12.3 1.1 7.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Bacteroidetes Cauli_VI PF01693.16 KIK60039.1 - 6.6e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Cauli_VI PF01693.16 KIK60040.1 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin C5HCH PF17982.1 KIK60040.1 - 0.88 9.8 4.0 12 6.1 0.3 2.4 2 0 0 2 2 2 0 NSD Cys-His rich domain MG2 PF01835.19 KIK60041.1 - 0.11 12.9 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 MG2 domain KDZ PF18758.1 KIK60042.1 - 1.1e-28 100.4 0.2 2.9e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase GST_N_3 PF13417.6 KIK60044.1 - 4.6e-14 52.6 0.0 8.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK60044.1 - 1.4e-11 44.5 0.0 3.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK60044.1 - 2.6e-09 37.3 0.0 5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK60044.1 - 0.012 15.6 0.0 0.071 13.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ImpE PF07024.13 KIK60044.1 - 0.052 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 ImpE protein GST_C_5 PF16865.5 KIK60044.1 - 0.081 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5077 PF16871.5 KIK60046.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) UPF0506 PF11703.8 KIK60047.1 - 9.7e-05 22.7 13.4 9.7e-05 22.7 13.4 1.5 1 1 0 1 1 1 1 UPF0506 Toxin_12 PF07740.12 KIK60047.1 - 0.2 12.4 16.4 3 8.6 7.2 2.6 1 1 1 2 2 2 0 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 KIK60047.1 - 2.7 8.2 22.0 0.21 11.7 3.9 2.4 3 0 0 3 3 3 0 I2-superfamily conotoxins Dickkopf_N PF04706.12 KIK60047.1 - 4.7 7.8 16.2 53 4.4 16.2 2.2 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Toxin_29 PF08116.11 KIK60047.1 - 8.9 6.4 20.9 0.7 9.9 2.9 3.2 2 1 0 2 2 2 0 PhTx neurotoxin family SurA_N_3 PF13624.6 KIK60049.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 SurA N-terminal domain DUF601 PF04642.12 KIK60050.1 - 0.033 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Ifi-6-16 PF06140.13 KIK60050.1 - 0.037 13.9 1.9 0.069 13.1 1.9 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family PEP-utilisers_N PF05524.13 KIK60050.1 - 0.048 13.8 0.4 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal HD PF01966.22 KIK60051.1 - 2.5e-08 34.2 0.0 3.9e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 HD domain OTCace PF00185.24 KIK60052.1 - 7.2e-42 143.1 0.0 9.7e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KIK60052.1 - 1.4e-21 77.0 0.0 2.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain AChE_tetra PF08674.10 KIK60053.1 - 1.7 8.4 5.0 9.1 6.1 0.1 2.3 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain PepSY_like PF11396.8 KIK60054.1 - 0.045 14.3 0.5 0.83 10.3 0.1 2.1 1 1 1 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Retrotrans_gag PF03732.17 KIK60055.1 - 2.5e-06 27.7 0.3 6.2e-05 23.2 0.2 2.3 1 1 0 1 1 1 1 Retrotransposon gag protein HEPN_Cthe2314 PF18730.1 KIK60055.1 - 0.0077 16.3 0.1 0.0096 16.0 0.1 1.1 1 0 0 1 1 1 1 Cthe_2314-like HEPN DUF4890 PF16231.5 KIK60056.1 - 0.17 12.4 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Cu_amine_oxidN2 PF02727.16 KIK60057.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Dimer_Tnp_hAT PF05699.14 KIK60059.1 - 3.2e-05 23.6 0.0 3.3e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK60060.1 - 0.045 14.1 0.1 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Ifi-6-16 PF06140.13 KIK60061.1 - 0.0024 17.8 1.5 0.0051 16.7 1.4 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family PEP-utilisers_N PF05524.13 KIK60061.1 - 0.068 13.3 0.2 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF601 PF04642.12 KIK60061.1 - 0.099 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 HD PF01966.22 KIK60062.1 - 7.4e-09 35.9 0.0 1.3e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 HD domain Caa3_CtaG PF09678.10 KIK60063.1 - 0.0096 15.4 0.4 0.0096 15.4 0.4 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) tRNA-synt_1 PF00133.22 KIK60063.1 - 0.22 9.7 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Acyl-CoA_dh_M PF02770.19 KIK60064.1 - 0.0041 17.3 0.0 0.0075 16.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KIK60064.1 - 0.076 13.2 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_3 PF07859.13 KIK60065.1 - 2.5e-20 73.2 0.0 4.1e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK60065.1 - 1.7e-15 56.8 0.0 2.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 KIK60066.1 - 2e-21 76.6 0.1 2.5e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family p450 PF00067.22 KIK60067.1 - 1.5e-54 185.5 0.0 2e-45 155.4 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIK60069.1 - 7.8e-77 259.0 0.1 2.2e-76 257.5 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 ATP-synt_J PF04911.12 KIK60069.1 - 0.09 12.4 0.5 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 ATP synthase j chain DUF1201 PF06716.11 KIK60070.1 - 0.12 12.5 2.9 0.18 11.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) MFS_1 PF07690.16 KIK60071.1 - 6.1e-25 87.9 52.7 2.9e-19 69.2 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_16 PF13191.6 KIK60073.1 - 0.0031 17.9 0.0 0.004 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK60073.1 - 0.0054 16.7 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK60073.1 - 0.0092 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 KIK60073.1 - 0.033 13.3 0.1 0.042 12.9 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KIK60073.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIK60073.1 - 0.039 13.4 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 KIK60073.1 - 0.061 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 KIK60073.1 - 0.064 13.2 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KIK60073.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK60073.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK60073.1 - 0.16 11.9 0.0 0.3 10.9 0.0 1.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 KIK60073.1 - 0.26 11.0 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK60074.1 - 0.00039 20.4 0.0 0.0008 19.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain CAS_CSE1 PF03378.15 KIK60075.1 - 3.6e-99 332.2 0.0 6.5e-99 331.4 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KIK60075.1 - 9.6e-90 301.1 0.0 2.4e-89 299.7 0.0 1.7 1 1 0 1 1 1 1 Cse1 IBN_N PF03810.19 KIK60075.1 - 5.9e-13 48.5 1.0 1e-10 41.3 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KIK60075.1 - 0.0015 18.6 0.3 0.028 14.5 0.0 3.3 3 1 0 3 3 3 1 Exportin 1-like protein SapB_2 PF03489.17 KIK60075.1 - 0.36 11.0 1.7 3.5 7.8 0.3 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 PS_Dcarbxylase PF02666.15 KIK60076.1 - 3.4e-48 163.9 0.0 4.6e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NACHT PF05729.12 KIK60078.1 - 2.4e-11 43.8 0.0 1.5e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK60078.1 - 3.2e-06 27.7 0.0 7.5e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK60078.1 - 0.015 15.6 0.0 0.16 12.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK60078.1 - 0.019 15.4 0.0 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 KIK60078.1 - 0.045 13.2 0.0 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA PF00004.29 KIK60078.1 - 0.14 12.6 0.1 0.79 10.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIK60078.1 - 0.22 11.2 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPRTase PF14681.6 KIK60079.1 - 2.1e-77 259.3 0.0 2.6e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIK60079.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain G6PD_C PF02781.16 KIK60080.1 - 2.8e-78 263.1 0.0 5.6e-40 137.4 0.0 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIK60080.1 - 1.1e-55 189.1 0.0 1.5e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3173 PF11372.8 KIK60082.1 - 1.8e-05 24.5 0.2 7.5 6.5 0.0 4.8 3 2 1 4 4 4 2 Domain of unknown function (DUF3173) DUF3911 PF13050.6 KIK60082.1 - 0.43 10.7 3.3 3.3 7.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3911) Motilin_assoc PF04643.12 KIK60082.1 - 1.1 9.2 8.2 80 3.2 0.1 4.4 5 0 0 5 5 5 0 Motilin/ghrelin-associated peptide AAA_16 PF13191.6 KIK60084.1 - 9.2e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK60084.1 - 0.00087 19.2 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK60084.1 - 0.0079 16.6 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIK60084.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK60084.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KIK60085.1 - 4.4e-05 23.5 0.0 5.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Abhydrolase_1 PF00561.20 KIK60086.1 - 3.3e-15 56.4 0.5 2.6e-14 53.5 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK60086.1 - 1.3e-13 52.1 4.4 2.5e-13 51.1 4.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK60086.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 WD40 PF00400.32 KIK60088.1 - 0.015 16.1 0.6 0.23 12.4 0.1 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2724 PF10893.8 KIK60088.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) APH PF01636.23 KIK60090.1 - 0.093 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_trans_2_3 PF13632.6 KIK60091.1 - 2.2e-52 177.8 3.5 8.9e-52 175.9 3.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK60091.1 - 0.0046 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK60091.1 - 0.0087 15.9 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 COX7a PF02238.15 KIK60091.1 - 0.24 11.8 3.3 6.5 7.2 0.7 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII DUF4598 PF15370.6 KIK60091.1 - 0.51 10.8 1.6 11 6.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) Glyco_trans_2_3 PF13632.6 KIK60092.1 - 0.033 14.1 0.9 0.13 12.1 0.3 2.3 2 1 0 2 2 2 0 Glycosyl transferase family group 2 Ank_2 PF12796.7 KIK60095.1 - 8.5e-29 100.0 6.8 1.4e-22 80.1 2.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60095.1 - 1.6e-23 82.1 2.3 6.1e-07 29.6 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KIK60095.1 - 1.7e-22 79.5 3.4 2.1e-10 40.9 0.2 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK60095.1 - 5.8e-22 77.5 4.6 7.5e-07 29.3 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK60095.1 - 4.2e-20 69.7 1.3 5.5e-05 23.3 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Goodbye PF17109.5 KIK60096.1 - 4.2e-17 62.7 0.3 1.4e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NPV_P10 PF05531.12 KIK60096.1 - 0.00082 19.8 5.2 0.58 10.7 0.1 3.5 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KIK60096.1 - 0.0029 17.6 3.7 0.22 11.5 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) Taxilin PF09728.9 KIK60096.1 - 0.023 13.9 1.8 0.034 13.3 1.8 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF1204 PF06721.11 KIK60096.1 - 0.088 12.2 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) AAA_16 PF13191.6 KIK60096.1 - 0.095 13.1 0.1 0.34 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Glyco_trans_2_3 PF13632.6 KIK60099.1 - 1.7e-11 44.4 1.0 9.4e-10 38.7 1.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Ig_6 PF18452.1 KIK60101.1 - 0.0019 17.7 0.1 0.0034 16.9 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Goodbye PF17109.5 KIK60102.1 - 5.3e-20 72.1 0.1 1.5e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain CAMP_factor PF07373.11 KIK60102.1 - 0.086 12.4 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 CAMP factor (Cfa) PhaP_Bmeg PF09602.10 KIK60102.1 - 0.15 11.9 2.9 5.2 7.0 0.1 2.7 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) NPV_P10 PF05531.12 KIK60102.1 - 0.3 11.6 2.8 56 4.3 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glyco_trans_2_3 PF13632.6 KIK60103.1 - 4.1e-13 49.7 0.6 6.4e-13 49.1 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Goodbye PF17109.5 KIK60106.1 - 1.4e-14 54.6 0.2 3e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NPV_P10 PF05531.12 KIK60106.1 - 0.03 14.8 1.4 0.85 10.1 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glyco_trans_2_3 PF13632.6 KIK60108.1 - 6.7e-07 29.4 0.0 9.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIK60108.1 - 0.00087 19.1 0.0 0.0018 18.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK60108.1 - 0.0089 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 FAD_binding_3 PF01494.19 KIK60110.1 - 5.1e-16 58.9 1.2 3.2e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KIK60110.1 - 0.0099 15.5 0.4 0.018 14.7 0.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK60110.1 - 0.01 15.1 0.2 0.51 9.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK60110.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK60110.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding WD40 PF00400.32 KIK60113.1 - 1.4e-29 101.7 19.3 3.5e-09 37.1 0.0 5.6 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK60113.1 - 4.1e-07 30.2 0.3 0.076 13.3 0.0 3.6 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK60113.1 - 4.7e-05 23.2 1.4 1.3 9.1 0.1 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat YdjM PF04307.14 KIK60113.1 - 0.038 13.3 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase PHB_acc_N PF07879.11 KIK60113.1 - 0.18 11.9 0.1 2.6 8.2 0.0 2.7 4 0 0 4 4 4 0 PHB/PHA accumulation regulator DNA-binding domain FCP1_C PF09309.10 KIK60113.1 - 0.21 11.4 0.0 17 5.2 0.0 2.7 1 1 2 3 3 3 0 FCP1, C-terminal Sdh_cyt PF01127.22 KIK60114.1 - 1.5e-24 86.4 1.2 1.9e-24 86.0 1.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M28 PF04389.17 KIK60116.1 - 4.7e-19 68.9 0.0 6.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK60116.1 - 1.7e-07 31.2 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 stn_TNFRSF12A PF12191.8 KIK60117.1 - 0.14 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DAP10 PF07213.11 KIK60117.1 - 0.14 12.1 0.2 0.39 10.7 0.1 1.7 1 1 1 2 2 2 0 DAP10 membrane protein MIR PF02815.19 KIK60120.1 - 0.024 14.5 0.1 0.025 14.4 0.1 1.0 1 0 0 1 1 1 0 MIR domain COPIIcoated_ERV PF07970.12 KIK60121.1 - 2.5e-22 79.8 1.6 3.3e-22 79.4 1.6 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter MULE PF10551.9 KIK60122.1 - 1.7e-06 28.3 0.0 5.7e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain FAD_binding_4 PF01565.23 KIK60124.1 - 3.1e-07 30.2 1.2 5.3e-07 29.5 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain Ank_2 PF12796.7 KIK60125.1 - 6.7e-18 65.1 9.7 3.2e-10 40.5 2.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60125.1 - 6.7e-16 57.9 17.6 1.4e-05 25.3 0.6 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KIK60125.1 - 2e-15 55.3 9.5 1.1e-05 25.3 0.3 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KIK60125.1 - 6.1e-14 52.2 7.5 1.2e-06 28.9 0.5 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK60125.1 - 4.1e-13 49.3 7.0 2e-05 24.8 0.4 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Tox-PL-2 PF15643.6 KIK60125.1 - 0.098 12.8 5.0 2.3 8.4 0.1 3.2 2 1 2 4 4 4 0 Papain fold toxin 2 COPIIcoated_ERV PF07970.12 KIK60126.1 - 6e-30 104.7 0.7 8.1e-30 104.3 0.7 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter FAD_binding_4 PF01565.23 KIK60129.1 - 6.7e-27 93.9 3.0 1e-26 93.3 3.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK60129.1 - 1.5e-12 47.4 0.1 2.8e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like SPX PF03105.19 KIK60132.1 - 2.8e-36 126.3 5.8 9.7e-25 88.3 0.0 2.1 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KIK60132.1 - 2.9e-32 112.1 47.1 1.7e-28 99.7 25.0 2.1 2 1 1 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.19 KIK60132.1 - 6.9e-32 111.1 25.7 9.8e-32 110.6 25.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region KilA-N PF04383.13 KIK60134.1 - 0.0039 17.0 0.1 1.7 8.6 0.0 2.2 2 0 0 2 2 2 2 KilA-N domain Orn_Arg_deC_N PF02784.16 KIK60135.1 - 5.4e-77 258.5 0.0 7.1e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIK60135.1 - 2.3e-15 56.6 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PTPA PF03095.15 KIK60137.1 - 6.3e-100 334.5 0.0 7.5e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ku PF02735.16 KIK60138.1 - 3.7e-38 131.3 0.0 1.6e-37 129.2 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KIK60138.1 - 4.3e-23 82.2 0.0 8.3e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KIK60138.1 - 6.9e-14 52.3 0.0 1.8e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KIK60138.1 - 1.3e-12 47.1 0.0 3.1e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 SAP domain Tyrosinase PF00264.20 KIK60139.1 - 3.3e-31 109.3 5.3 4.3e-31 108.9 5.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase F-box-like PF12937.7 KIK60140.1 - 0.00015 21.6 0.7 0.00043 20.1 0.3 2.1 2 0 0 2 2 2 1 F-box-like LRR_9 PF14580.6 KIK60140.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat F-box PF00646.33 KIK60140.1 - 0.033 14.1 0.1 0.13 12.2 0.1 2.1 1 0 0 1 1 1 0 F-box domain Glutaredoxin PF00462.24 KIK60141.1 - 4.6e-19 68.4 0.0 6e-18 64.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KIK60141.1 - 1.9e-05 24.6 0.0 6.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 KIK60141.1 - 7.3e-05 22.7 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE SH3BGR PF04908.15 KIK60141.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 KIK60141.1 - 0.033 14.6 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 KIK60141.1 - 0.041 14.3 0.0 0.92 10.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Phosducin PF02114.16 KIK60141.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosducin Isochorismatase PF00857.20 KIK60142.1 - 3.3e-13 50.2 0.0 3.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family COPIIcoated_ERV PF07970.12 KIK60143.1 - 4.1e-36 124.9 0.6 6.2e-36 124.3 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIK60143.1 - 2.4e-21 75.9 0.0 4e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Goodbye PF17109.5 KIK60144.1 - 1e-10 42.1 0.1 1e-10 42.1 0.1 2.3 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain DUF1664 PF07889.12 KIK60144.1 - 0.0063 16.6 1.9 0.38 10.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KIK60144.1 - 0.026 15.0 5.4 4.3 7.9 0.0 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FixS PF03597.15 KIK60145.1 - 0.023 14.4 0.7 2.1 8.1 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF2615 PF11027.8 KIK60145.1 - 0.082 13.1 0.3 4.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF1181 PF06680.11 KIK60145.1 - 0.87 9.4 4.4 7.2 6.4 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1181) Goodbye PF17109.5 KIK60146.1 - 7e-14 52.3 0.2 2.6e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KIK60146.1 - 9.8e-11 41.8 0.0 2.5e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK60146.1 - 5.5e-07 30.1 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK60146.1 - 5e-06 26.6 0.2 2.3e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK60146.1 - 0.00031 21.0 0.0 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2309 PF10070.9 KIK60146.1 - 0.0015 17.0 0.1 0.0028 16.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) RNA_helicase PF00910.22 KIK60146.1 - 0.0016 18.8 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KIK60146.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 KIK60146.1 - 0.019 15.4 4.6 7.3 7.1 0.0 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KIK60146.1 - 0.049 13.7 3.4 1.2 9.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Nnf1 PF03980.14 KIK60146.1 - 0.052 13.9 0.2 0.21 12.0 0.2 2.0 1 0 0 1 1 1 0 Nnf1 AAA_14 PF13173.6 KIK60146.1 - 0.099 12.7 0.1 0.97 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Glyco_trans_2_3 PF13632.6 KIK60147.1 - 4.3e-08 33.3 0.0 4.6e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 TEX12 PF15219.6 KIK60147.1 - 0.05 13.9 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Testis-expressed 12 COPIIcoated_ERV PF07970.12 KIK60149.1 - 7.2e-30 104.5 1.0 5.4e-29 101.6 1.0 1.9 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter Goodbye PF17109.5 KIK60150.1 - 4.6e-18 65.8 0.1 8e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NPV_P10 PF05531.12 KIK60150.1 - 0.0009 19.7 0.4 0.54 10.7 0.0 2.3 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Mlp PF03304.13 KIK60150.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Mlp lipoprotein family Mu-like_Pro PF10123.9 KIK60150.1 - 0.062 12.9 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein MIT PF04212.18 KIK60151.1 - 1e-05 25.5 1.0 0.62 10.2 0.1 3.6 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KIK60151.1 - 0.00027 21.2 11.4 3.2 8.1 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK60151.1 - 0.0023 17.8 0.4 1.2 9.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60151.1 - 0.018 15.1 9.0 12 6.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60151.1 - 0.066 13.1 6.9 14 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK60151.1 - 2.4 9.2 7.4 52 5.1 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 KIK60152.1 - 3.6e-26 91.5 2.4 5.5e-26 91.0 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK60152.1 - 8.9e-10 38.5 0.1 1.7e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like MAP17 PF15807.5 KIK60154.1 - 0.031 14.5 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 UPF0560 PF10577.9 KIK60154.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TED_complement PF07678.14 KIK60159.1 - 0.16 11.0 0.3 0.26 10.3 0.3 1.2 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF3584 PF12128.8 KIK60159.1 - 0.41 8.1 4.9 0.59 7.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Herpes_gE PF02480.16 KIK60161.1 - 0.11 11.2 0.3 0.35 9.6 0.0 1.8 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E TPR_10 PF13374.6 KIK60164.1 - 3.7e-117 379.5 14.5 4.9e-12 45.3 0.0 11.9 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK60164.1 - 1.2e-101 333.1 45.0 1.2e-16 60.7 0.1 9.5 1 1 8 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60164.1 - 7.5e-26 88.1 26.6 0.042 14.0 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK60164.1 - 2.3e-22 79.8 11.7 9.7e-12 44.9 3.5 2.7 1 1 0 2 2 2 2 MalT-like TPR region TPR_17 PF13431.6 KIK60164.1 - 9.1e-22 75.8 11.7 0.23 11.9 0.0 11.1 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60164.1 - 1.2e-20 72.4 27.6 0.32 10.9 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 KIK60164.1 - 3.5e-15 54.8 27.3 0.15 12.1 0.0 11.2 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_4 PF07721.14 KIK60164.1 - 1.5e-14 53.0 0.0 1.1 10.0 0.0 9.3 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK60164.1 - 1.8e-12 46.4 31.8 1.1 9.6 0.1 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat Ribosomal_L18p PF00861.22 KIK60164.1 - 2e-11 44.3 0.0 10 6.5 0.0 8.8 1 1 9 10 10 10 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TPR_3 PF07720.12 KIK60164.1 - 4.3e-10 39.4 4.9 1.7 8.8 0.0 7.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIK60164.1 - 1e-09 38.8 0.0 4 8.2 0.0 7.8 3 2 6 9 9 8 1 Tetratricopeptide repeat RPN7 PF10602.9 KIK60164.1 - 2e-09 37.4 4.4 0.33 10.6 0.0 6.5 3 2 5 8 8 8 3 26S proteasome subunit RPN7 TPR_19 PF14559.6 KIK60164.1 - 1.4e-07 31.9 15.6 5.1 7.7 0.1 8.4 2 2 8 10 10 10 1 Tetratricopeptide repeat PPR PF01535.20 KIK60164.1 - 6.1e-07 29.3 22.9 0.42 11.0 0.1 10.1 10 0 0 10 10 10 1 PPR repeat ATPgrasp_N PF18130.1 KIK60164.1 - 1.2e-05 25.7 4.5 96 3.6 0.1 8.2 9 1 1 10 10 10 0 ATP-grasp N-terminal domain Spore_YpjB PF09577.10 KIK60164.1 - 6.1e-05 22.9 1.4 6.4 6.5 0.0 4.7 2 2 0 4 4 4 1 Sporulation protein YpjB (SpoYpjB) TPR_14 PF13428.6 KIK60164.1 - 0.00021 21.9 10.6 1.7e+02 3.4 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK60164.1 - 0.0016 18.8 0.3 1.8e+02 2.6 0.0 6.6 8 1 1 9 9 9 0 Tetratricopeptide repeat Flu_NS2 PF00601.19 KIK60164.1 - 0.017 15.4 7.8 2 8.8 0.3 5.9 2 2 2 4 4 4 0 Influenza non-structural protein (NS2) MORN_2 PF07661.13 KIK60164.1 - 0.098 12.9 0.7 15 6.2 0.0 3.8 4 0 0 4 4 2 0 MORN repeat variant PDU_like PF15953.5 KIK60164.1 - 0.11 12.6 0.0 13 5.8 0.0 3.8 3 0 0 3 3 3 0 Putative propanediol utilisation EP400_N PF15790.5 KIK60164.1 - 0.68 8.7 1.4 42 2.8 0.0 3.3 4 1 0 4 4 4 0 E1A-binding protein p400, N-terminal TPR_11 PF13414.6 KIK60164.1 - 4.1 7.2 20.0 33 4.3 0.1 8.3 10 0 0 10 10 9 0 TPR repeat PPR_2 PF13041.6 KIK60164.1 - 5.2 7.4 8.6 67 3.8 0.0 6.3 10 0 0 10 10 10 0 PPR repeat family DUF1129 PF06570.11 KIK60166.1 - 0.022 14.3 0.8 0.17 11.3 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) ORC4_C PF14629.6 KIK60166.1 - 0.024 14.0 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Cyt_c_ox_IV PF12270.8 KIK60166.1 - 0.077 13.1 1.3 0.14 12.3 1.3 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase subunit IV TACI-CRD2 PF09305.10 KIK60167.1 - 0.11 12.6 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 TACI, cysteine-rich domain TPR_10 PF13374.6 KIK60168.1 - 5e-93 302.8 0.1 3.3e-11 42.7 0.0 9.2 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK60168.1 - 6.6e-75 247.4 13.8 1.6e-16 60.3 0.1 8.7 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.6 KIK60168.1 - 8e-24 82.3 5.4 0.17 12.3 0.0 8.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60168.1 - 1.4e-23 81.0 11.0 0.016 15.2 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60168.1 - 3.5e-21 74.1 11.4 0.0067 16.2 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK60168.1 - 2.7e-17 61.4 7.1 0.044 13.8 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK60168.1 - 4.1e-15 56.0 0.3 9.7e-05 21.9 0.2 3.3 1 1 2 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 KIK60168.1 - 1.4e-14 53.0 18.8 0.012 15.8 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK60168.1 - 6e-11 42.7 0.3 1.3 9.6 0.0 7.1 1 1 7 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK60168.1 - 5.4e-09 35.8 0.0 5.6 7.9 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 KIK60168.1 - 4.9e-08 32.7 16.3 1.6 9.2 0.0 7.9 8 0 0 8 8 8 2 PPR repeat TPR_16 PF13432.6 KIK60168.1 - 1.4e-06 28.8 0.0 25 5.6 0.0 6.5 5 2 3 8 8 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK60168.1 - 5.4e-06 26.3 3.8 2.5 8.2 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.9 KIK60168.1 - 3.3e-05 23.6 1.2 2.8 7.6 0.0 4.7 2 2 5 7 7 7 2 26S proteasome subunit RPN7 Spore_YpjB PF09577.10 KIK60168.1 - 0.00015 21.6 0.6 3.8 7.2 0.0 4.8 4 2 1 5 5 5 1 Sporulation protein YpjB (SpoYpjB) MORN_2 PF07661.13 KIK60168.1 - 0.00071 19.5 2.0 9.4 6.8 0.1 5.0 5 0 0 5 5 4 0 MORN repeat variant ECSCR PF15820.5 KIK60168.1 - 0.071 12.9 0.1 68 3.4 0.0 4.5 4 2 2 6 6 6 0 Endothelial cell-specific chemotaxis regulator TPR_11 PF13414.6 KIK60168.1 - 0.1 12.3 6.9 38 4.1 0.1 6.1 7 0 0 7 7 7 0 TPR repeat Phage_base_V PF04717.12 KIK60168.1 - 0.2 11.6 0.8 69 3.4 0.0 4.2 4 2 1 5 5 4 0 Type VI secretion system, phage-baseplate injector TPR_6 PF13174.6 KIK60168.1 - 6.7 7.6 5.9 4.6e+02 1.8 0.0 5.2 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF2944 PF11161.8 KIK60169.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) IATP PF04568.12 KIK60170.1 - 1.2 9.6 6.8 3 8.3 6.8 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Trypan_PARP PF05887.11 KIK60170.1 - 2.2 8.2 12.2 4.5 7.2 12.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPPK_C PF12555.8 KIK60174.1 - 0.093 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal YHYH PF14240.6 KIK60175.1 - 0.056 13.4 0.4 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 YHYH protein MUG113 PF13455.6 KIK60179.1 - 9.3e-08 32.6 0.1 2.3e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK60179.1 - 0.00036 21.0 0.0 0.00063 20.3 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain DcuC PF03606.15 KIK60182.1 - 0.007 14.9 1.0 0.0093 14.5 1.0 1.1 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier MAP17 PF15807.5 KIK60182.1 - 0.0088 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LPG_synthase_TM PF03706.13 KIK60182.1 - 0.029 13.9 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region UPF0560 PF10577.9 KIK60182.1 - 0.06 11.9 0.0 0.088 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TPR_10 PF13374.6 KIK60183.1 - 8e-77 251.3 1.0 2.3e-10 40.0 0.0 8.0 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK60183.1 - 3.4e-68 225.9 15.3 2.8e-14 53.1 0.1 6.7 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KIK60183.1 - 1.8e-23 80.8 7.2 0.048 13.7 0.0 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60183.1 - 5.4e-22 76.6 8.1 0.039 13.8 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60183.1 - 3.4e-21 73.6 4.5 0.22 11.7 0.0 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 KIK60183.1 - 4.6e-20 70.5 1.5 0.47 11.0 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK60183.1 - 5.7e-20 69.8 15.9 0.049 13.9 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK60183.1 - 9.2e-17 61.4 3.0 7.8e-06 25.5 0.1 3.0 1 1 2 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 KIK60183.1 - 3.6e-10 40.2 0.8 11 6.7 0.0 6.9 2 1 5 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK60183.1 - 3.7e-10 39.4 0.0 15 6.6 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KIK60183.1 - 5.8e-10 38.7 11.6 3.1 8.2 0.0 7.2 7 0 0 7 7 7 2 PPR repeat TPR_16 PF13432.6 KIK60183.1 - 4e-08 33.8 0.1 6.9 7.4 0.0 6.4 3 2 4 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KIK60183.1 - 1.1e-05 25.2 0.2 5 6.8 0.0 4.2 2 1 2 4 4 4 2 26S proteasome subunit RPN7 DUF1897 PF09005.10 KIK60183.1 - 0.0002 20.8 4.0 6.9 6.2 0.0 5.4 7 0 0 7 7 7 1 Domain of unknown function (DUF1897) TPR_14 PF13428.6 KIK60183.1 - 0.0013 19.4 5.6 54 5.0 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_5 PF12688.7 KIK60183.1 - 0.0032 17.7 5.6 0.044 14.0 0.1 3.9 2 2 1 4 4 4 1 Tetratrico peptide repeat TPR_11 PF13414.6 KIK60183.1 - 0.0042 16.7 6.2 22 4.9 0.0 6.1 7 0 0 7 7 7 0 TPR repeat Spore_YpjB PF09577.10 KIK60183.1 - 0.019 14.8 0.3 3 7.6 0.0 3.1 3 1 0 3 3 3 0 Sporulation protein YpjB (SpoYpjB) ATPgrasp_N PF18130.1 KIK60183.1 - 0.021 15.4 0.3 40 4.8 0.0 3.9 4 1 0 4 4 4 0 ATP-grasp N-terminal domain SPOB_a PF14689.6 KIK60183.1 - 0.4 10.4 10.2 16 5.3 0.0 5.4 6 0 0 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_6 PF13174.6 KIK60183.1 - 4.2 8.2 7.5 5.1e+02 1.7 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK60185.1 - 4.8e-239 767.0 4.8 2.4e-11 43.1 0.0 21.0 21 0 0 21 21 21 20 Tetratricopeptide repeat TPR_12 PF13424.6 KIK60185.1 - 6.6e-195 631.9 68.6 1.2e-15 57.6 0.2 17.2 1 1 19 20 20 20 20 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60185.1 - 4e-56 182.7 33.8 0.022 14.9 0.0 20.0 20 0 0 20 20 20 15 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK60185.1 - 3.8e-50 171.2 39.9 8.7e-11 41.8 2.5 6.8 1 1 8 9 9 9 9 MalT-like TPR region TPR_17 PF13431.6 KIK60185.1 - 1.4e-49 163.0 14.5 0.17 12.3 0.0 20.2 20 0 0 20 20 20 12 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60185.1 - 9.3e-45 148.7 42.6 0.27 11.1 0.1 20.2 20 0 0 20 20 20 17 Tetratricopeptide repeat TPR_7 PF13176.6 KIK60185.1 - 4.4e-44 145.3 32.4 0.085 12.9 0.0 20.0 20 0 0 20 20 20 10 Tetratricopeptide repeat TPR_8 PF13181.6 KIK60185.1 - 3.5e-29 98.5 55.1 0.17 12.1 0.1 18.7 19 0 0 19 19 19 9 Tetratricopeptide repeat TPR_4 PF07721.14 KIK60185.1 - 1.5e-24 84.0 0.0 3.3 8.6 0.0 16.8 19 0 0 19 19 17 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK60185.1 - 1.4e-21 76.7 6.1 2.2 8.8 0.0 14.4 4 4 13 18 18 17 4 Tetratricopeptide repeat Ribosomal_L18p PF00861.22 KIK60185.1 - 6e-21 75.0 0.0 7.5 7.0 0.0 16.1 1 1 18 19 19 19 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TPR_16 PF13432.6 KIK60185.1 - 1.2e-19 70.6 0.0 8.5 7.1 0.0 14.6 4 3 11 15 15 14 1 Tetratricopeptide repeat PPR PF01535.20 KIK60185.1 - 2.6e-13 49.2 52.6 0.58 10.5 0.1 17.7 20 0 0 20 20 20 3 PPR repeat RPN7 PF10602.9 KIK60185.1 - 4.5e-13 49.3 13.5 0.98 9.1 0.1 11.4 4 4 7 13 13 13 2 26S proteasome subunit RPN7 TPR_3 PF07720.12 KIK60185.1 - 5.9e-13 48.5 5.1 1.8 8.7 0.0 11.5 13 0 0 13 13 13 2 Tetratricopeptide repeat MORN_2 PF07661.13 KIK60185.1 - 8.7e-07 28.5 5.5 25 5.5 0.1 7.8 6 0 0 6 6 6 0 MORN repeat variant ATPgrasp_ST PF14397.6 KIK60185.1 - 0.025 13.8 0.1 78 2.4 0.0 6.4 9 0 0 9 9 9 0 Sugar-transfer associated ATP-grasp BRO1 PF03097.18 KIK60185.1 - 0.13 11.0 4.7 15 4.3 0.0 5.2 6 0 0 6 6 6 0 BRO1-like domain PPR_2 PF13041.6 KIK60185.1 - 0.22 11.7 16.6 60 4.0 0.0 9.3 11 1 1 12 12 10 0 PPR repeat family DUF1802 PF08819.11 KIK60185.1 - 2.1 8.2 4.5 1e+02 2.6 0.0 5.4 7 0 0 7 7 6 0 Domain of unknown function (DUF1802) EP400_N PF15790.5 KIK60185.1 - 2.8 6.7 7.1 37 3.0 0.0 5.1 4 2 2 6 6 6 0 E1A-binding protein p400, N-terminal ResIII PF04851.15 KIK60186.1 - 0.0027 17.7 0.1 0.0076 16.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KIK60186.1 - 0.0064 15.7 0.1 0.017 14.3 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain Fib_succ_major PF09603.10 KIK60186.1 - 0.013 16.2 0.0 0.028 15.1 0.0 1.6 1 1 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) Picorna_P3A PF06363.11 KIK60186.1 - 0.03 14.2 0.1 0.086 12.7 0.1 1.7 1 0 0 1 1 1 0 Picornaviridae P3A protein AAA_16 PF13191.6 KIK60186.1 - 0.037 14.4 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KIK60186.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KIK60186.1 - 0.065 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KIK60186.1 - 0.076 13.3 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain LytR_C PF13399.6 KIK60186.1 - 0.11 13.4 0.0 0.3 12.1 0.0 1.7 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator AAA_30 PF13604.6 KIK60186.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK60188.1 - 0.0043 17.5 0.0 0.0048 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.17 KIK60188.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK60188.1 - 0.05 14.0 0.0 0.08 13.3 0.0 1.4 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK60188.1 - 0.052 13.1 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIK60188.1 - 0.057 14.0 0.1 0.089 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK60188.1 - 0.066 13.1 0.1 0.082 12.8 0.1 1.1 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KIK60188.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.6 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK60188.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase TniB PF05621.11 KIK60188.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 KIK60188.1 - 0.12 11.7 0.1 0.63 9.3 0.1 1.9 2 0 0 2 2 2 0 KaiC Fungal_trans PF04082.18 KIK60190.1 - 1.3e-22 80.1 0.2 4.5e-22 78.3 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK60190.1 - 2e-08 34.2 10.8 3.2e-08 33.6 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.22 KIK60191.1 - 3.9e-45 153.2 0.2 3.1e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KIK60191.1 - 4.2e-30 103.3 0.3 8.2e-15 54.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KIK60191.1 - 6.6e-10 38.5 0.0 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KIK60191.1 - 2.3e-08 34.0 0.0 2.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain ARD PF03079.14 KIK60191.1 - 2.5e-06 27.8 0.0 0.02 15.1 0.0 2.3 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.18 KIK60191.1 - 1.4e-05 25.0 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 KIK60191.1 - 0.001 18.8 0.0 0.15 11.7 0.0 2.5 3 0 0 3 3 3 1 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.12 KIK60191.1 - 0.017 15.3 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Ectoine synthase DUF1971 PF09313.11 KIK60191.1 - 0.12 12.4 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) Cupin_4 PF08007.12 KIK60191.1 - 0.13 11.7 0.0 5.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein DcpS_C PF11969.8 KIK60192.1 - 1.4e-20 73.9 0.1 1.7e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIK60192.1 - 3e-08 34.3 0.7 6.4e-08 33.2 0.7 1.5 1 1 0 1 1 1 1 HIT domain Kazal_1 PF00050.21 KIK60192.1 - 0.048 13.7 0.3 0.083 12.9 0.3 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Acetyltransf_7 PF13508.7 KIK60195.1 - 1.2e-07 32.1 0.1 2.8e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK60195.1 - 1.3e-05 25.4 0.0 4.5e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK60195.1 - 1.5e-05 24.9 0.9 0.17 11.9 0.0 2.9 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK60195.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KIK60196.1 - 1.3e-06 28.8 0.0 2.7e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK60196.1 - 6.6e-05 22.8 0.2 0.32 11.0 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK60196.1 - 0.00034 20.8 0.0 0.0009 19.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_5 PF13857.6 KIK60196.1 - 0.00059 20.1 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK60196.1 - 0.019 15.5 0.0 0.069 13.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK60196.1 - 0.021 15.4 0.1 1.8 9.2 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KIK60196.1 - 0.043 14.3 0.0 0.17 12.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Forkhead PF00250.18 KIK60197.1 - 5.6e-19 68.2 0.0 1.3e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain PDCD7 PF16021.5 KIK60197.1 - 0.041 13.0 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 YL1 PF05764.13 KIK60198.1 - 0.00013 22.2 6.4 0.00017 21.8 6.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 KIK60198.1 - 0.069 11.4 4.6 0.082 11.2 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KIK60198.1 - 0.19 11.1 10.6 0.25 10.7 10.6 1.1 1 0 0 1 1 1 0 SDA1 AF-4 PF05110.13 KIK60198.1 - 0.24 9.5 4.7 0.28 9.2 4.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.12 KIK60198.1 - 2 6.5 11.5 2.4 6.2 11.5 1.0 1 0 0 1 1 1 0 Nop14-like family TAF PF02969.17 KIK60199.1 - 0.17 12.1 0.2 5.9 7.1 0.0 3.0 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) Amidohydro_1 PF01979.20 KIK60200.1 - 9.3e-34 117.3 0.0 1.2e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK60200.1 - 2.9e-14 53.4 0.2 6e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Pterin_bind PF00809.22 KIK60200.1 - 0.012 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme MR_MLE_C PF13378.6 KIK60200.1 - 0.074 12.6 0.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 Enolase C-terminal domain-like ADH_N PF08240.12 KIK60201.1 - 1.3e-23 82.9 0.1 3.3e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK60201.1 - 1.8e-16 60.3 0.0 3.3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK60201.1 - 2.3e-09 38.4 0.0 4.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK60201.1 - 0.016 14.7 0.5 0.028 13.9 0.5 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KIK60201.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 KIK60202.1 - 4.1e-27 95.1 17.0 1.6e-19 70.0 11.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK60202.1 - 5.5e-08 32.1 9.3 1.1e-07 31.1 9.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK60202.1 - 0.00011 21.7 5.8 0.00011 21.7 5.8 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB F-box-like PF12937.7 KIK60203.1 - 6.5e-05 22.8 1.3 6.5e-05 22.8 1.3 2.6 2 0 0 2 2 2 1 F-box-like Hus1 PF04005.12 KIK60204.1 - 2.7e-77 259.8 2.8 3e-77 259.6 2.8 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.16 KIK60204.1 - 6.7e-05 22.1 0.2 0.00012 21.3 0.2 1.4 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 LegC3_N PF18654.1 KIK60204.1 - 0.064 12.5 0.3 0.064 12.5 0.3 1.5 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain DUF2663 PF10864.8 KIK60205.1 - 0.59 10.5 2.3 1.5 9.3 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF3810 PF12725.7 KIK60205.1 - 0.67 9.2 3.1 1.2 8.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) G-alpha PF00503.20 KIK60207.1 - 2.2e-46 158.6 0.2 5.2e-41 141.0 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KIK60207.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Abhydrolase_6 PF12697.7 KIK60208.1 - 2.2e-27 97.1 0.0 3.9e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK60208.1 - 1.1e-08 34.6 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK60208.1 - 1.3e-08 34.9 0.0 2.5e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK60208.1 - 0.00074 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KIK60208.1 - 0.0043 17.2 0.0 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 KIK60208.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KIK60211.1 - 1.9e-23 83.0 42.5 2e-15 56.6 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK60211.1 - 3.7e-13 49.2 15.8 7.6e-13 48.1 15.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.16 KIK60211.1 - 0.00036 18.9 2.1 0.12 10.5 0.0 2.1 2 0 0 2 2 2 2 BT1 family Mit_ribos_Mrp51 PF11709.8 KIK60211.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Pkinase_fungal PF17667.1 KIK60212.1 - 1e-07 31.1 0.0 1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK60212.1 - 0.015 14.7 0.0 0.068 12.5 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK60212.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK60212.1 - 0.2 11.6 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK60213.1 - 0.082 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyoxalase_3 PF13468.6 KIK60215.1 - 4.4e-23 82.3 0.0 7.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain PKD_2 PF16407.5 KIK60215.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 PKD-like family UbiA PF01040.18 KIK60219.1 - 2.2e-23 82.8 11.6 2.9e-23 82.5 11.6 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KIK60220.1 - 4e-57 194.0 0.0 5e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribo_biogen_C PF04034.13 KIK60220.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal DUF1295 PF06966.12 KIK60221.1 - 1.1e-13 51.2 0.1 1.5e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KIK60221.1 - 0.00043 19.2 3.4 0.0011 17.8 3.4 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KIK60221.1 - 0.016 15.2 0.7 0.023 14.7 0.7 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KIK60221.1 - 0.04 14.4 0.1 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Erf4 PF10256.9 KIK60225.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF5607 PF18355.1 KIK60225.1 - 0.069 13.6 0.1 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5607) DUF2717 PF10911.8 KIK60225.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) DUF1201 PF06716.11 KIK60227.1 - 8.4 6.5 8.0 3 7.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) KleE PF17394.2 KIK60228.1 - 1.7 8.9 7.4 0.13 12.5 1.3 2.3 2 1 0 2 2 2 0 Uncharacterized KleE stable inheritance protein IncE PF17627.2 KIK60229.1 - 0.13 12.3 5.5 4.5 7.3 2.4 2.6 2 0 0 2 2 2 0 Inclusion membrane protein E NmrA PF05368.13 KIK60230.1 - 4.8e-14 52.5 0.0 6.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK60230.1 - 3.1e-11 43.5 0.0 4.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KIK60230.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KIK60230.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFA PF04828.14 KIK60231.1 - 6.8e-13 48.8 0.0 9.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cation_efflux PF01545.21 KIK60232.1 - 1.7e-43 148.7 10.3 2.2e-43 148.3 10.3 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KIK60232.1 - 0.0051 16.0 0.8 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF2043 PF09740.9 KIK60232.1 - 0.17 12.6 0.0 0.31 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2043) DUF5325 PF17259.2 KIK60232.1 - 0.61 10.0 6.1 0.064 13.1 1.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Glyco_hydro_7 PF00840.20 KIK60233.1 - 1.6e-196 653.2 18.8 1.9e-196 653.0 18.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FlaE PF07559.14 KIK60233.1 - 0.0034 17.9 1.4 0.0034 17.9 1.4 2.4 2 1 0 2 2 2 1 Flagellar basal body protein FlaE MFS_1 PF07690.16 KIK60234.1 - 6e-28 97.8 36.9 9.7e-28 97.1 33.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK60234.1 - 2.8e-15 56.1 10.9 3.7e-15 55.8 10.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2530 PF10745.9 KIK60234.1 - 9.1 6.6 8.5 0.36 11.1 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 KIK60236.1 - 1.6e-15 56.9 10.9 1.6e-15 56.9 10.9 3.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK60236.1 - 3e-11 42.8 5.2 3e-11 42.8 5.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK60237.1 - 2.1e-32 112.4 62.4 6.9e-29 100.9 31.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK60237.1 - 6.7e-12 45.0 14.7 1e-11 44.4 14.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK60237.1 - 0.00023 19.8 0.6 0.00038 19.0 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Disulph_isomer PF06491.11 KIK60239.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase DivIC PF04977.15 KIK60239.1 - 6.7 6.6 11.2 2.3e+02 1.7 12.2 2.3 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 KIK60240.1 - 5.4e-32 111.1 59.9 5.3e-28 98.0 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK60240.1 - 0.00028 19.4 0.8 0.00047 18.7 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Viral_Beta_CD PF04530.12 KIK60241.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.7 3 1 1 4 4 4 0 Viral Beta C/D like family G-alpha PF00503.20 KIK60242.1 - 1.1e-66 225.5 1.3 1.3e-66 225.2 1.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK60242.1 - 5.3e-06 26.0 0.6 2.8e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family FAD_binding_4 PF01565.23 KIK60242.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF3417 PF11897.8 KIK60242.1 - 0.15 12.5 0.4 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF4139 PF13598.6 KIK60243.1 - 1.3e-25 90.4 0.0 1e-24 87.4 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIK60243.1 - 7.1e-13 48.8 0.0 2.1e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 KIK60243.1 - 1.3e-05 25.9 75.3 0.00091 20.0 25.7 3.9 1 1 2 3 3 3 3 Nucleoporin FG repeat region CP2 PF04516.15 KIK60243.1 - 0.098 11.9 0.2 0.24 10.7 0.2 1.6 1 0 0 1 1 1 0 CP2 transcription factor COX6B PF02297.17 KIK60244.1 - 4.8e-22 78.0 2.3 6.3e-22 77.6 2.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SOBP PF15279.6 KIK60245.1 - 9.8 6.7 12.4 16 6.0 12.4 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein N-glycanase_C PF09113.10 KIK60249.1 - 0.058 13.2 0.2 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Peptide-N-glycosidase F, C terminal GCM PF03615.15 KIK60250.1 - 0.00051 19.9 1.5 0.0012 18.8 1.5 1.5 1 0 0 1 1 1 1 GCM motif protein PHD PF00628.29 KIK60250.1 - 4.1 7.4 9.8 0.5 10.3 5.2 2.0 2 0 0 2 2 2 0 PHD-finger WD40 PF00400.32 KIK60252.1 - 2.1e-112 363.8 89.2 2.9e-10 40.6 0.2 14.9 15 0 0 15 15 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK60252.1 - 1.7e-23 82.7 25.1 0.0032 17.7 0.1 11.6 1 1 11 13 13 13 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK60252.1 - 1.5e-12 47.5 17.1 0.035 13.4 0.4 8.0 3 1 2 7 7 7 5 WD40-like domain NACHT PF05729.12 KIK60252.1 - 1.1e-07 31.9 0.0 3.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK60252.1 - 4e-06 27.3 0.0 1.6e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Frtz PF11768.8 KIK60252.1 - 5e-06 25.1 4.4 0.53 8.5 0.1 5.9 1 1 7 8 8 8 2 WD repeat-containing and planar cell polarity effector protein Fritz NB-ARC PF00931.22 KIK60252.1 - 3.6e-05 23.1 0.0 7.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Ge1_WD40 PF16529.5 KIK60252.1 - 0.00041 19.4 11.3 1.5 7.7 0.0 7.1 3 2 4 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1258 PF06869.12 KIK60252.1 - 0.0012 18.4 1.7 19 4.7 0.0 5.0 2 2 3 6 6 6 0 Protein of unknown function (DUF1258) PD40 PF07676.12 KIK60252.1 - 0.0059 16.5 0.2 1.5e+02 2.4 0.0 5.8 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.22 KIK60252.1 - 0.012 16.0 0.1 0.25 11.8 0.0 2.8 2 1 1 3 3 3 0 RNA helicase TMF_DNA_bd PF12329.8 KIK60252.1 - 0.019 15.0 0.2 0.038 14.0 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_22 PF13401.6 KIK60252.1 - 0.072 13.4 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK60252.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Citrate_ly_lig PF08218.11 KIK60252.1 - 0.15 11.7 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain AAA PF00004.29 KIK60252.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Retrotran_gag_2 PF14223.6 KIK60253.1 - 3e-16 59.3 0.4 4.4e-16 58.8 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Macoilin PF09726.9 KIK60253.1 - 0.058 12.0 6.8 0.07 11.7 6.8 1.1 1 0 0 1 1 1 0 Macoilin family gag_pre-integrs PF13976.6 KIK60254.1 - 7.1e-07 29.0 1.3 7.1e-07 29.0 1.3 1.5 2 0 0 2 2 2 1 GAG-pre-integrase domain Hyr1 PF15789.5 KIK60255.1 - 1.4 8.5 4.1 1.4 8.5 2.5 1.8 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 CDC45 PF02724.14 KIK60257.1 - 0.25 9.6 7.8 0.33 9.2 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_3 PF13358.6 KIK60258.1 - 2.8e-07 30.4 0.0 2.9e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK60259.1 - 1.3e-07 31.4 0.4 1.5e-07 31.3 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_4 PF01565.23 KIK60261.1 - 2.5e-23 82.4 0.4 4.1e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK60261.1 - 1.1e-05 25.5 0.3 2.5e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like RT_RNaseH_2 PF17919.1 KIK60263.1 - 7e-10 38.8 0.0 9.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK60263.1 - 1.7e-09 37.9 0.0 5.6e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Aldo_ket_red PF00248.21 KIK60264.1 - 5.6e-76 255.6 0.0 6.3e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KIK60265.1 - 5.9e-61 206.4 0.0 8.3e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK60265.1 - 9.5e-34 117.0 0.2 1.5e-33 116.4 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK60265.1 - 7.4e-05 22.9 0.1 0.00058 20.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK60265.1 - 0.0024 17.5 0.3 0.071 12.7 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK60265.1 - 0.0052 16.1 0.0 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK60265.1 - 0.01 15.0 0.7 2.6 7.0 0.5 2.3 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIK60265.1 - 0.018 14.1 0.2 0.088 11.8 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein KDZ PF18758.1 KIK60266.1 - 0.0022 17.6 5.1 0.0025 17.4 5.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase IRF-2BP1_2 PF11261.8 KIK60266.1 - 1.1 8.9 6.1 0.16 11.6 1.4 2.0 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Terpene_synth_C PF03936.16 KIK60267.1 - 2.5e-05 23.8 0.0 3.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIK60267.1 - 0.0076 15.2 0.1 0.078 11.8 0.0 2.0 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) p450 PF00067.22 KIK60268.1 - 2.9e-70 237.3 0.0 1.9e-69 234.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK60269.1 - 2.6e-58 197.9 0.0 6.4e-58 196.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK60270.1 - 6.6e-48 163.6 0.0 1.7e-46 159.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Chromo_2 PF18704.1 KIK60270.1 - 1.7 9.0 3.4 22 5.4 0.0 2.8 3 0 0 3 3 3 0 Chromatin organization modifier domain 2 PIF1 PF05970.14 KIK60271.1 - 1.1e-21 77.4 0.0 1.2e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KIK60272.1 - 1.7e-20 73.5 0.1 1.9e-20 73.3 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK60272.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain zf-CCCH_6 PF18585.1 KIK60272.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 AAA_19 PF13245.6 KIK60272.1 - 0.17 12.2 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain RVP_2 PF08284.11 KIK60275.1 - 0.0048 16.7 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease THDPS_N_2 PF14805.6 KIK60275.1 - 0.019 15.2 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DDE_3 PF13358.6 KIK60277.1 - 0.089 12.6 0.0 0.097 12.4 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Sel1 PF08238.12 KIK60278.1 - 1.4e-18 66.9 11.0 4.8e-06 27.1 0.3 6.2 6 0 0 6 6 6 4 Sel1 repeat TPR_8 PF13181.6 KIK60278.1 - 0.002 18.2 0.3 0.68 10.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60278.1 - 0.0085 16.1 10.5 0.06 13.5 0.0 5.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60278.1 - 0.032 14.1 7.4 2.6 8.0 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK60278.1 - 0.8 10.4 3.8 20 6.0 0.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK60278.1 - 7.7 7.6 6.6 61 4.8 0.0 4.7 5 1 2 7 7 7 0 Tetratricopeptide repeat Hexapep PF00132.24 KIK60279.1 - 1.2e-08 34.3 19.3 9.9e-05 21.9 3.1 4.8 4 1 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIK60279.1 - 1.4e-05 24.7 12.1 0.0033 17.1 1.4 3.9 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KIK60279.1 - 0.0015 17.6 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase STT3 PF02516.14 KIK60280.1 - 2.1e-144 482.1 35.8 3.7e-139 464.8 32.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ceramidase_alk PF04734.13 KIK60282.1 - 2.3e-211 702.8 0.0 2.8e-211 702.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KIK60282.1 - 5e-53 179.4 0.4 8.5e-53 178.7 0.4 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal TEA PF01285.18 KIK60284.1 - 3.6e-22 78.2 0.0 5.9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain MS_channel PF00924.18 KIK60286.1 - 4e-17 62.5 0.6 7.6e-17 61.5 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIK60286.1 - 5.6e-06 25.5 0.1 1.3e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIK60286.1 - 5.1e-05 22.9 0.1 0.00015 21.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KIK60286.1 - 0.00071 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KIK60286.1 - 0.0018 17.7 0.1 0.0052 16.2 0.1 1.8 1 0 0 1 1 1 1 EF hand DUF2207 PF09972.9 KIK60286.1 - 0.018 13.8 0.5 0.11 11.3 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SUR7 PF06687.12 KIK60286.1 - 0.12 12.0 5.9 1.1 8.8 0.8 2.4 2 0 0 2 2 2 0 SUR7/PalI family ABC_membrane PF00664.23 KIK60287.1 - 2.4e-63 214.4 31.7 1e-33 117.2 6.8 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK60287.1 - 8.1e-55 185.1 0.0 6.3e-33 114.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK60287.1 - 3.2e-07 30.0 0.0 0.024 14.1 0.0 3.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK60287.1 - 3.4e-05 24.3 0.9 0.0089 16.4 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KIK60287.1 - 0.0002 21.4 0.8 0.075 13.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KIK60287.1 - 0.00068 19.5 3.7 2 8.2 0.1 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIK60287.1 - 0.0038 17.2 0.2 2.1 8.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF4574 PF15141.6 KIK60287.1 - 0.0044 16.9 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA_29 PF13555.6 KIK60287.1 - 0.011 15.5 0.7 0.5 10.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KIK60287.1 - 0.019 15.0 1.5 3.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 KIK60287.1 - 0.025 14.7 5.7 0.85 9.7 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_ATPase PF09818.9 KIK60287.1 - 0.036 12.9 0.0 0.087 11.6 0.0 1.6 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 KIK60287.1 - 0.042 14.4 0.4 8 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK60287.1 - 0.074 12.8 0.5 10 5.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK60287.1 - 0.22 10.8 0.2 11 5.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KIK60287.1 - 0.23 11.0 1.6 3 7.4 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KIK60287.1 - 0.37 11.1 2.9 11 6.2 0.1 3.4 2 1 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 KIK60288.1 - 1.9e-64 216.7 0.0 2.5e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KIK60288.1 - 6.1e-08 33.2 0.2 2.3e-07 31.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIK60288.1 - 2.4e-06 27.7 0.0 2.7e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK60288.1 - 0.00022 21.1 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIK60288.1 - 0.00032 21.0 0.0 0.00048 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK60288.1 - 0.0014 19.2 0.0 0.0049 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK60288.1 - 0.0016 18.5 0.0 0.06 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK60288.1 - 0.0025 18.2 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KIK60288.1 - 0.003 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 KIK60288.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK60288.1 - 0.017 15.7 0.0 0.018 15.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIK60288.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KIK60288.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK60288.1 - 0.027 14.4 0.1 0.19 11.6 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KIK60288.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KIK60288.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 KIK60288.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KIK60288.1 - 0.048 14.1 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK60288.1 - 0.05 12.8 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 KIK60288.1 - 0.066 12.4 0.0 0.4 9.9 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 KIK60288.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK60288.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WEMBL PF05701.11 KIK60288.1 - 0.072 11.8 0.1 0.095 11.4 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light AAA_24 PF13479.6 KIK60288.1 - 0.089 12.5 0.0 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KIK60288.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.3 1 1 0 1 1 1 0 Septin Pkinase PF00069.25 KIK60289.1 - 9.3e-63 212.0 0.0 2.1e-62 210.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60289.1 - 2.2e-32 112.3 0.0 3.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK60289.1 - 2.8e-09 36.7 0.0 4.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK60289.1 - 1.9e-05 23.6 0.0 3.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK60289.1 - 0.0007 19.0 2.3 0.0008 18.8 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK60289.1 - 0.0044 17.0 0.3 0.01 15.8 0.3 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK60289.1 - 0.038 13.6 0.1 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIK60289.1 - 0.086 11.8 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF4212 PF13937.6 KIK60290.1 - 3.9 7.9 12.9 6.5 7.2 9.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) GDP_Man_Dehyd PF16363.5 KIK60292.1 - 6.4e-43 147.4 0.0 1.2e-42 146.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK60292.1 - 1.7e-41 142.3 0.0 2.4e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK60292.1 - 1.3e-11 44.1 0.0 7.5e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIK60292.1 - 2.3e-11 43.3 0.0 1.3e-09 37.4 0.0 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIK60292.1 - 8.7e-10 38.2 0.1 1.8e-08 33.9 0.0 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KIK60292.1 - 4.3e-06 26.7 0.1 1.2e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KIK60292.1 - 6.2e-05 22.3 0.0 0.00029 20.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KIK60292.1 - 0.018 14.5 0.0 0.55 9.7 0.0 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KIK60292.1 - 0.11 12.4 0.0 3 7.7 0.0 2.4 1 1 0 1 1 1 0 NAD(P)H-binding Nitroreductase PF00881.24 KIK60293.1 - 9.1e-28 97.4 0.0 1.3e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIK60293.1 - 2e-08 34.1 0.3 0.0044 16.6 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase Pyr_redox_2 PF07992.14 KIK60294.1 - 2.1e-28 99.4 0.0 2.8e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK60294.1 - 9.2e-13 48.6 0.5 2.4e-09 37.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK60294.1 - 2.3e-06 27.7 0.6 0.017 15.1 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK60294.1 - 8.8e-06 25.2 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK60294.1 - 0.00012 21.3 0.2 1.3 8.0 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KIK60294.1 - 0.00075 18.5 0.6 0.014 14.3 0.1 2.7 4 0 0 4 4 4 1 Tryptophan halogenase Thi4 PF01946.17 KIK60294.1 - 0.0019 17.5 0.4 0.38 10.0 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KIK60294.1 - 0.002 17.8 7.0 0.85 9.1 2.4 3.5 1 1 3 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIK60294.1 - 0.0056 15.9 0.2 2.1 7.4 0.0 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KIK60294.1 - 0.0089 14.8 0.3 0.55 8.9 0.0 3.0 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.6 KIK60294.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KIK60294.1 - 0.063 13.5 1.0 10 6.4 0.1 2.7 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_3 PF01494.19 KIK60294.1 - 0.088 12.0 1.4 0.15 11.3 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KIK60294.1 - 0.12 12.5 0.0 25 4.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK60294.1 - 0.17 12.2 0.4 36 4.6 0.1 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 KIK60294.1 - 0.27 10.3 5.9 1.1 8.2 0.0 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KIK60295.1 - 5.7e-58 196.6 0.0 7.2e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK60295.1 - 4.8e-29 101.7 0.1 8e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK60295.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Spt5-NGN PF03439.13 KIK60297.1 - 2.3e-21 75.5 0.0 4.8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KIK60297.1 - 1.8e-17 62.6 27.8 4.9e-07 29.5 1.2 5.9 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.8 KIK60297.1 - 3.4e-17 63.2 11.4 3.4e-17 63.2 11.4 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KIK60297.1 - 1.2e-11 45.0 45.1 1.2e-09 38.6 16.8 3.9 2 2 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 SAGA-Tad1 PF12767.7 KIK60299.1 - 9.5e-25 87.7 0.2 1.4e-24 87.1 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KIK60299.1 - 0.0086 15.9 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family PTCB-BRCT PF12738.7 KIK60300.1 - 5e-22 77.6 0.1 3e-11 43.1 0.0 2.8 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KIK60300.1 - 2.7e-14 53.3 0.0 8.3e-08 32.5 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIK60300.1 - 5.8e-05 23.4 0.0 0.037 14.4 0.0 3.3 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIK60300.1 - 0.00014 22.1 0.0 0.0086 16.3 0.0 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Mito_carr PF00153.27 KIK60301.1 - 6.7e-67 221.5 0.5 4.7e-23 80.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK60301.1 - 0.0084 15.3 0.7 0.97 8.5 0.0 3.1 2 1 1 3 3 3 2 Gammaproteobacterial serine protease KduI PF04962.12 KIK60301.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 KduI/IolB family Pribosyltran PF00156.27 KIK60302.1 - 2.3e-06 27.2 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain p450 PF00067.22 KIK60303.1 - 4.3e-58 197.2 0.0 5.4e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_25 PF17933.1 KIK60303.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2897 PF11446.8 KIK60304.1 - 0.037 13.9 4.4 0.055 13.4 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pollen_allerg_2 PF01620.16 KIK60304.1 - 0.063 13.5 0.5 0.076 13.2 0.5 1.1 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) zf-C3HC4_3 PF13920.6 KIK60305.1 - 4.8e-08 32.7 4.5 1.7e-07 30.9 4.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 KIK60305.1 - 5.9e-08 33.4 11.5 2.8e-06 28.0 0.6 3.4 2 1 1 3 3 3 2 Torus domain zf-C3HC4 PF00097.25 KIK60305.1 - 7e-08 32.2 2.6 2.6e-07 30.4 2.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 KIK60305.1 - 5.2e-07 29.3 34.2 0.00061 19.5 9.0 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger zf-RING_2 PF13639.6 KIK60305.1 - 3.3e-06 27.3 5.8 3.3e-06 27.3 5.8 2.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK60305.1 - 3.5e-06 26.9 3.4 6.6e-06 26.1 2.2 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK60305.1 - 5e-06 26.4 4.5 5e-06 26.4 4.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KIK60305.1 - 1.6e-05 24.8 11.7 1.6e-05 24.8 11.7 5.0 4 1 0 4 4 4 1 Zinc finger domain zf-CCCH PF00642.24 KIK60305.1 - 0.00021 21.1 27.5 0.00093 19.1 4.5 3.7 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KIK60305.1 - 0.0013 19.2 31.3 0.056 13.9 2.7 3.7 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-C3HC4_2 PF13923.6 KIK60305.1 - 0.0041 16.9 1.1 0.0041 16.9 1.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK60305.1 - 0.0047 17.2 3.3 0.0047 17.2 3.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain YyzF PF14116.6 KIK60305.1 - 0.029 14.4 0.3 3.1 7.9 0.1 2.7 2 0 0 2 2 2 0 YyzF-like protein zf-C3HC4_4 PF15227.6 KIK60305.1 - 0.23 11.7 6.5 1 9.6 6.5 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIK60305.1 - 0.23 11.3 11.2 0.033 14.1 5.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KIK60305.1 - 0.74 10.0 6.1 3.7 7.8 6.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KIK60305.1 - 1.8 8.7 11.4 1.6 8.9 5.6 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CCCH_3 PF15663.5 KIK60305.1 - 7.6 6.8 15.5 1.9 8.8 3.4 3.3 2 1 1 3 3 3 0 Zinc-finger containing family PAT1 PF09770.9 KIK60307.1 - 4.8e-98 329.5 80.3 1.9e-95 320.9 80.3 3.9 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 hDGE_amylase PF14701.6 KIK60308.1 - 1.2e-160 535.4 0.0 1.5e-160 535.1 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KIK60308.1 - 4.4e-123 411.0 0.0 5.8e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KIK60308.1 - 1.7e-79 267.1 0.0 2.3e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KIK60308.1 - 1.2e-23 83.0 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme PDZ_6 PF17820.1 KIK60308.1 - 0.0076 16.1 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 1 PDZ domain Pkinase PF00069.25 KIK60309.1 - 3.2e-63 213.6 0.0 3.9e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60309.1 - 2.2e-23 82.9 0.0 8.4e-23 81.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK60309.1 - 0.0036 16.6 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK60309.1 - 0.0043 16.1 0.1 0.007 15.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIK60309.1 - 0.035 13.2 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIK60309.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase S_100 PF01023.19 KIK60309.1 - 0.39 10.5 3.2 0.41 10.4 1.9 1.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain UCR_6-4kD PF08997.10 KIK60311.1 - 0.035 14.0 2.1 0.31 11.0 0.2 3.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein CPSase_L_D2 PF02786.17 KIK60312.1 - 9.9e-81 270.3 0.1 1.9e-80 269.3 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KIK60312.1 - 9.7e-67 224.6 0.0 1.8e-66 223.7 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KIK60312.1 - 6.3e-40 136.2 0.1 1.3e-39 135.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK60312.1 - 1.7e-30 105.3 0.0 6.4e-30 103.4 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KIK60312.1 - 8.3e-27 94.4 0.0 1.8e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KIK60312.1 - 4.9e-17 61.5 7.2 1.1e-16 60.4 5.9 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIK60312.1 - 1.2e-10 41.1 6.0 4.3e-05 23.2 0.2 2.8 3 0 0 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KIK60312.1 - 5.1e-10 39.2 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIK60312.1 - 4.8e-08 32.8 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KIK60312.1 - 3.2e-06 27.3 0.0 8.5e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KIK60312.1 - 2e-05 25.3 2.0 0.24 12.1 0.3 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KIK60312.1 - 3.7e-05 23.0 1.7 0.0059 15.8 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 KIK60312.1 - 0.00039 20.0 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KIK60312.1 - 0.00091 19.1 2.9 0.0048 16.8 0.9 3.1 4 1 0 4 4 4 1 Glycine cleavage H-protein RnfC_N PF13375.6 KIK60312.1 - 0.002 18.0 2.3 0.026 14.5 2.0 2.6 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain RimK PF08443.11 KIK60312.1 - 0.0035 16.9 0.0 0.015 14.9 0.0 2.1 2 1 0 2 2 1 1 RimK-like ATP-grasp domain NQRA PF05896.11 KIK60312.1 - 0.0044 16.5 0.9 0.011 15.2 0.9 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 KIK60312.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KIK60312.1 - 0.025 13.8 0.0 0.061 12.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KIK60312.1 - 0.028 14.4 1.1 0.51 10.3 1.2 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.22 KIK60312.1 - 0.1 12.8 1.1 3.3 8.0 1.1 3.3 1 1 0 1 1 1 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 KIK60312.1 - 0.11 12.3 0.3 0.75 9.6 0.1 2.4 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NMO PF03060.15 KIK60313.1 - 1.3e-40 139.9 1.4 1.9e-39 136.0 1.4 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK60313.1 - 4.7e-06 25.8 0.2 0.038 13.0 0.0 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK60313.1 - 8.5e-06 25.0 0.2 1.1e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KIK60313.1 - 0.054 12.7 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase WD40 PF00400.32 KIK60314.1 - 2.1e-13 50.5 12.4 2.3e-05 25.0 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat PAP_central PF04928.17 KIK60319.1 - 0.14 11.1 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain HET PF06985.11 KIK60320.1 - 0.00011 22.6 0.0 0.00011 22.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C12 PF01088.21 KIK60321.1 - 6.6e-53 179.6 0.0 8.1e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1640 PF07798.11 KIK60322.1 - 2.8e-59 200.1 11.0 3.3e-59 199.9 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DotU PF09850.9 KIK60322.1 - 0.00012 21.8 1.7 1 9.0 0.0 3.1 3 0 0 3 3 3 2 Type VI secretion system protein DotU KIAA1430 PF13879.6 KIK60322.1 - 0.031 15.0 5.0 0.057 14.2 5.0 1.5 1 0 0 1 1 1 0 KIAA1430 homologue Phage_GP20 PF06810.11 KIK60322.1 - 0.041 13.7 11.7 0.051 13.4 11.7 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Uso1_p115_C PF04871.13 KIK60322.1 - 0.47 10.8 12.6 0.13 12.6 8.3 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KIK60322.1 - 0.98 9.9 6.3 0.25 11.7 0.9 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KIK60322.1 - 6.7 6.9 10.1 1.3 9.2 1.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fungal_TACC PF12709.7 KIK60322.1 - 9.6 6.7 12.1 9.1 6.8 4.6 3.1 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins FA_hydroxylase PF04116.13 KIK60323.1 - 2.3e-22 79.8 9.0 2.3e-22 79.8 9.0 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Rcd1 PF04078.13 KIK60324.1 - 3.9e-125 416.4 4.5 4.4e-125 416.2 4.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Abhydrolase_3 PF07859.13 KIK60326.1 - 4.6e-18 65.8 0.0 8.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK60326.1 - 2.6e-13 49.6 0.0 8.5e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KIK60326.1 - 0.049 13.4 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1295 PF06966.12 KIK60327.1 - 5.3e-50 170.1 2.5 7.7e-50 169.6 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK60327.1 - 9.2e-05 22.8 0.5 0.00059 20.2 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK60327.1 - 0.00013 22.3 0.0 0.00013 22.3 0.0 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KIK60327.1 - 0.0002 21.4 0.3 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Say1_Mug180 PF10340.9 KIK60328.1 - 5.5e-17 61.7 0.0 4e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KIK60328.1 - 1.4e-15 57.7 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK60328.1 - 0.21 10.4 0.1 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Thaumatin PF00314.17 KIK60329.1 - 1.5e-05 24.7 7.5 0.0016 18.1 2.5 3.0 1 1 1 2 2 2 2 Thaumatin family DNA_ligase_A_M PF01068.21 KIK60331.1 - 2.5e-21 76.3 0.1 2.9e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK60331.1 - 2.2e-14 54.2 0.0 4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KIK60331.1 - 0.0022 18.3 0.0 0.0071 16.7 0.0 1.9 1 1 0 1 1 1 1 RNA ligase ADH_zinc_N PF00107.26 KIK60332.1 - 2.2e-17 63.2 0.0 6.1e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK60332.1 - 4.3e-07 31.1 0.0 8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK60332.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain baeRF_family3 PF18845.1 KIK60332.1 - 0.042 14.1 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 DUF3395 PF11875.8 KIK60333.1 - 0.00059 19.7 0.0 0.00087 19.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) Methyltransf_11 PF08241.12 KIK60335.1 - 3.9e-19 69.1 0.0 1.3e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK60335.1 - 4.2e-19 69.0 0.0 1.5e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK60335.1 - 1e-15 57.9 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK60335.1 - 3.5e-12 46.5 0.0 6.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK60335.1 - 1.5e-10 40.8 0.0 5.9e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KIK60335.1 - 4.2e-10 39.4 0.0 8.6e-10 38.4 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIK60335.1 - 4.4e-10 40.2 0.0 1.2e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK60335.1 - 2.5e-06 27.2 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KIK60335.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KIK60335.1 - 0.0006 19.7 0.0 0.02 14.8 0.0 2.3 1 1 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.14 KIK60335.1 - 0.0032 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 KIK60335.1 - 0.0046 16.1 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KIK60335.1 - 0.0046 16.7 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KIK60335.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Sterol_MT_C PF08498.10 KIK60335.1 - 0.011 16.1 0.5 0.19 12.1 0.1 2.4 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal PrmA PF06325.13 KIK60335.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 KIK60335.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 KIK60335.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 KIK60336.1 - 0.011 15.7 1.0 0.011 15.7 1.0 2.8 2 1 0 2 2 2 0 F-box-like DIOX_N PF14226.6 KIK60337.1 - 6.3e-26 91.4 0.0 1.1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK60337.1 - 1e-16 61.2 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5320 PF17253.2 KIK60338.1 - 0.017 16.2 4.8 0.22 12.6 1.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) API5 PF05918.11 KIK60338.1 - 0.2 10.4 15.1 1.5 7.5 7.5 2.2 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Sds3 PF08598.11 KIK60339.1 - 2.9e-16 60.1 1.3 7.7e-16 58.8 1.4 1.5 1 1 1 2 2 2 1 Sds3-like Ribosomal_60s PF00428.19 KIK60341.1 - 3.7e-15 56.3 0.1 4.2e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KIK60341.1 - 0.032 14.6 0.7 0.035 14.4 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain FANCI_S1-cap PF14674.6 KIK60341.1 - 0.053 13.6 0.2 0.095 12.8 0.2 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap Ribosomal_60s PF00428.19 KIK60342.1 - 3e-27 95.0 8.9 3.6e-27 94.8 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KIK60342.1 - 0.0012 19.1 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain Phage-MuB_C PF09077.11 KIK60342.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Mu B transposition protein, C terminal UBA_6 PF18039.1 KIK60342.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain RibD_C PF01872.17 KIK60342.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Ribosomal_S19 PF00203.21 KIK60343.1 - 1.3e-32 111.5 0.3 2.1e-32 110.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KIK60343.1 - 0.0072 16.4 0.0 0.0083 16.2 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH ATP19 PF11022.8 KIK60345.1 - 1.6e-20 73.2 0.4 2.1e-20 72.9 0.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Ribosomal_S27e PF01667.17 KIK60346.1 - 0.012 15.3 6.7 1.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein S27 DZR PF12773.7 KIK60346.1 - 0.024 14.7 5.3 3.1 7.9 0.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon DUF2767 PF10965.8 KIK60346.1 - 0.17 11.9 0.6 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) zf-UDP PF14569.6 KIK60346.1 - 3.7 7.7 13.1 9.9 6.4 0.1 3.0 3 1 0 3 3 3 0 Zinc-binding RING-finger PLATZ PF04640.14 KIK60346.1 - 6.2 7.5 7.0 10 6.8 4.1 2.6 2 1 0 2 2 2 0 PLATZ transcription factor DPCD PF14913.6 KIK60347.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 DPCD protein family TPD52 PF04201.15 KIK60348.1 - 0.28 10.8 4.3 3.9 7.1 0.9 2.9 3 0 0 3 3 3 0 Tumour protein D52 family Fungal_trans PF04082.18 KIK60349.1 - 9e-16 57.7 0.1 1.7e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK60349.1 - 8.4e-05 22.6 9.3 0.00015 21.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KIK60349.1 - 0.013 15.9 0.2 0.013 15.9 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ExoD PF06055.12 KIK60349.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD zf-C2H2_4 PF13894.6 KIK60349.1 - 3.9 8.6 5.9 0.81 10.7 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger ARD PF03079.14 KIK60351.1 - 3.7e-14 53.2 0.1 7.2e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIK60351.1 - 2.4e-07 30.4 0.1 4.2e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 KIK60351.1 - 0.017 15.5 0.0 0.037 14.5 0.0 1.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase AraC_binding PF02311.19 KIK60351.1 - 0.047 13.6 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK60351.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KIK60351.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.4 1 1 0 1 1 1 0 Cupin Pkinase PF00069.25 KIK60354.1 - 9.2e-63 212.1 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60354.1 - 6.3e-26 91.2 0.0 1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK60354.1 - 0.0052 16.1 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK60354.1 - 0.012 14.5 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK60354.1 - 0.032 14.2 0.9 0.19 11.6 0.3 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family S_100 PF01023.19 KIK60354.1 - 0.055 13.2 1.1 0.14 11.8 1.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Kdo PF06293.14 KIK60354.1 - 0.11 11.8 0.2 0.24 10.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KIK60356.1 - 2.9e-15 56.0 0.0 7.6e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK60356.1 - 1.3e-09 38.0 9.8 2e-09 37.4 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 KIK60356.1 - 0.035 14.1 8.8 0.08 12.9 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) polyprenyl_synt PF00348.17 KIK60357.1 - 9.7e-86 287.0 0.0 1.3e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 KIK60358.1 - 3.3e-64 216.8 0.0 4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60358.1 - 1.2e-26 93.6 0.0 1.7e-26 93.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK60358.1 - 0.00068 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK60358.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK60358.1 - 0.0081 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK60358.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KIK60358.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KIK60358.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DHHC PF01529.20 KIK60359.1 - 4.1e-33 114.3 6.4 4.1e-33 114.3 6.4 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KIK60359.1 - 1.7e-32 111.8 0.1 1.5e-15 57.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK60359.1 - 9.7e-28 95.9 0.4 3.6e-10 39.9 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KIK60359.1 - 6.3e-26 89.6 0.1 8.7e-06 26.0 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KIK60359.1 - 8.7e-23 80.4 0.8 3.3e-07 30.7 0.3 5.8 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK60359.1 - 5.2e-22 75.6 0.9 0.00011 22.3 0.0 6.1 7 0 0 7 7 7 4 Ankyrin repeat ChapFlgA_N PF17656.1 KIK60360.1 - 0.024 14.8 0.7 0.3 11.3 0.2 2.4 2 1 0 2 2 2 0 FlgA N-terminal domain Period_C PF12114.8 KIK60360.1 - 1.5 8.4 10.5 2 7.9 10.5 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region EMP24_GP25L PF01105.24 KIK60361.1 - 1.6e-51 174.9 1.0 1.8e-51 174.7 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PAP_RNA-bind PF04926.15 KIK60361.1 - 0.028 14.0 0.4 0.057 13.1 0.2 1.6 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain DUF3578 PF12102.8 KIK60361.1 - 0.065 12.8 0.1 0.099 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) Cas_VVA1548 PF09652.10 KIK60361.1 - 0.11 12.7 0.4 0.27 11.5 0.4 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) MctB PF11382.8 KIK60361.1 - 0.12 12.1 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB RhoGAP PF00620.27 KIK60363.1 - 2.5e-36 124.8 0.0 4.7e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KIK60363.1 - 2.5e-25 88.5 28.4 1.3e-10 41.3 7.6 4.6 5 0 0 5 5 5 4 LIM domain SLC35F PF06027.12 KIK60364.1 - 1.2e-93 313.9 18.4 1.5e-93 313.6 18.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KIK60364.1 - 3.9e-09 35.9 0.6 3.9e-09 35.9 0.6 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KIK60364.1 - 0.00093 19.4 24.7 0.05 13.8 8.1 2.7 2 1 1 3 3 3 2 EamA-like transporter family DUF2628 PF10947.8 KIK60364.1 - 7 7.1 12.9 3.5 8.1 3.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) V-ATPase_G PF03179.15 KIK60365.1 - 1.2e-35 122.2 16.7 1.5e-35 121.9 16.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Seryl_tRNA_N PF02403.22 KIK60365.1 - 0.069 13.4 10.3 0.063 13.5 8.2 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArAE_2_N PF10337.9 KIK60365.1 - 0.28 10.2 3.7 0.31 10.0 3.7 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CHASE6_C PF17150.4 KIK60365.1 - 0.49 11.1 3.9 4.1 8.1 0.1 2.3 1 1 1 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain ATP-synt_B PF00430.18 KIK60365.1 - 1.3 9.1 18.6 0.59 10.2 15.2 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF1542 PF07564.11 KIK60365.1 - 2.3 8.4 13.2 0.46 10.6 0.9 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) Symplekin_C PF12295.8 KIK60366.1 - 8e-62 208.6 0.6 2.7e-61 206.9 0.6 2.0 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KIK60366.1 - 8.8e-50 169.4 2.4 2.8e-49 167.8 2.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT PF02985.22 KIK60366.1 - 0.0015 18.6 0.3 1.5 9.3 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat V-ATPase_H_C PF11698.8 KIK60366.1 - 0.071 13.2 0.3 47 4.1 0.0 3.6 3 0 0 3 3 3 0 V-ATPase subunit H Pkinase PF00069.25 KIK60367.1 - 2.4e-57 194.3 0.0 1.2e-56 192.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60367.1 - 9.9e-28 97.1 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK60367.1 - 0.0013 17.8 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK60367.1 - 0.0048 16.3 0.1 0.0093 15.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK60367.1 - 0.051 13.5 1.2 0.26 11.2 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DDE_1 PF03184.19 KIK60369.1 - 8.1e-05 22.4 0.0 9.1e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1122 PF06557.11 KIK60369.1 - 0.019 14.4 0.0 0.8 9.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1122) Sushi_2 PF09014.10 KIK60369.1 - 0.047 13.6 1.8 0.11 12.4 0.4 2.0 1 1 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain DDE_1 PF03184.19 KIK60370.1 - 2.6e-07 30.5 0.0 3e-07 30.2 0.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 KIK60371.1 - 2.9e-06 27.4 0.0 7.4e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK60371.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4939) Flu_B_M2 PF04772.12 KIK60372.1 - 0.016 15.4 1.5 0.025 14.8 0.9 1.6 1 1 1 2 2 2 0 Influenza B matrix protein 2 (BM2) DUF4666 PF15697.5 KIK60372.1 - 0.022 15.4 0.1 0.035 14.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) HA2 PF04408.23 KIK60372.1 - 0.15 12.3 2.6 0.21 11.9 2.6 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Pkinase PF00069.25 KIK60374.1 - 2.7e-56 190.8 0.0 5.2e-56 189.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60374.1 - 9.5e-25 87.3 0.0 4.3e-24 85.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RGCC PF15151.6 KIK60374.1 - 0.0082 16.4 0.3 0.03 14.6 0.3 1.9 1 0 0 1 1 1 1 Response gene to complement 32 protein family Haspin_kinase PF12330.8 KIK60374.1 - 0.023 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK60374.1 - 0.064 13.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK60374.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ParA PF10609.9 KIK60376.1 - 3e-95 318.3 0.0 3.8e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK60376.1 - 2.4e-08 34.1 0.0 6.8e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK60376.1 - 3.2e-05 23.2 1.7 0.0022 17.2 0.1 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KIK60376.1 - 0.0011 18.9 0.2 0.0092 15.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KIK60376.1 - 0.0032 17.3 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KIK60376.1 - 0.0036 16.8 0.0 0.0092 15.5 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KIK60376.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KIK60376.1 - 0.017 14.6 0.0 1.6 8.1 0.0 2.6 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KIK60376.1 - 0.022 14.7 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KIK60376.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 KIK60376.1 - 0.089 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Phosphoesterase PF04185.14 KIK60377.1 - 3.1e-75 253.6 0.0 4.3e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family CrtC PF07143.11 KIK60378.1 - 0.042 14.5 0.0 0.055 14.1 0.0 1.2 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain Spo7_2_N PF15407.6 KIK60379.1 - 0.046 13.3 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Sporulation protein family 7 UPF0014 PF03649.13 KIK60383.1 - 3.6e-69 232.8 19.2 4.7e-69 232.4 19.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) RPAP1_C PF08620.10 KIK60384.1 - 1.5e-18 66.7 0.1 5.2e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 RPAP1-like, C-terminal Asp PF00026.23 KIK60385.1 - 1.7e-35 123.0 0.0 2.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK60385.1 - 2.9e-07 30.9 6.4 0.0065 16.7 5.1 4.0 3 1 0 3 3 3 2 Xylanase inhibitor N-terminal zf-C2H2_4 PF13894.6 KIK60389.1 - 0.099 13.5 9.3 0.65 11.0 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DLIC PF05783.11 KIK60389.1 - 0.16 10.7 0.4 0.25 10.1 0.4 1.2 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) zf-met PF12874.7 KIK60389.1 - 0.39 11.2 5.3 11 6.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK60390.1 - 0.079 13.8 9.4 0.12 13.3 0.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KIK60390.1 - 0.17 12.3 0.5 0.17 12.3 0.5 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIK60390.1 - 1.7 9.3 8.7 2.1 9.0 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK60391.1 - 0.046 14.6 8.6 0.2 12.6 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KIK60391.1 - 0.12 12.8 3.2 0.43 11.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PcF PF09461.10 KIK60391.1 - 0.32 11.4 3.2 6.5 7.2 0.3 2.3 2 0 0 2 2 2 0 Phytotoxin PcF protein zf-C2H2 PF00096.26 KIK60391.1 - 6.6 7.4 11.2 3.7 8.2 1.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Lyase_1 PF00206.20 KIK60394.1 - 1e-114 383.2 0.0 1.3e-61 208.7 0.0 2.1 2 0 0 2 2 2 2 Lyase FumaraseC_C PF10415.9 KIK60394.1 - 5.4e-20 71.6 0.1 1.1e-19 70.5 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus RRM_1 PF00076.22 KIK60395.1 - 1e-31 108.5 1.9 2.5e-15 56.0 0.1 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK60395.1 - 6.5e-06 26.2 0.0 0.0007 19.7 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 KIK60395.1 - 0.00074 19.3 0.0 0.87 9.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KIK60395.1 - 0.0026 17.6 0.0 0.77 9.7 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Myc_N PF01056.18 KIK60396.1 - 1.8 8.4 4.7 1.9 8.3 4.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Fis1_TPR_C PF14853.6 KIK60397.1 - 1.2e-22 79.7 0.4 2.3e-22 78.8 0.4 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KIK60397.1 - 1.5e-15 56.5 0.0 2.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KIK60397.1 - 0.00075 19.4 0.4 0.0015 18.5 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK60397.1 - 0.017 15.0 0.4 0.032 14.0 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK60397.1 - 0.053 14.2 0.1 0.17 12.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TraI_2_C PF07515.11 KIK60397.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term Gram_pos_anchor PF00746.21 KIK60397.1 - 0.76 9.8 3.1 1.2 9.1 3.1 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_M50B PF13398.6 KIK60398.1 - 1.6e-42 145.5 15.9 1.8e-42 145.2 15.9 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Histone PF00125.24 KIK60399.1 - 1.1e-16 61.4 0.5 1.3e-16 61.1 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK60399.1 - 2.1e-13 49.8 0.7 3.6e-13 49.0 0.7 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK60399.1 - 9.8e-08 32.2 0.1 1.6e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3071 PF11268.8 KIK60399.1 - 0.0045 17.1 0.0 0.0074 16.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3071) TFIID-18kDa PF02269.16 KIK60399.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Peptidase_M20 PF01546.28 KIK60400.1 - 2.4e-30 105.8 0.0 2.1e-29 102.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK60400.1 - 3.2e-12 46.3 0.0 6.9e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK60400.1 - 0.0036 17.0 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 ABC_tran PF00005.27 KIK60401.1 - 1.5e-26 93.5 0.0 4e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK60401.1 - 9.3e-10 38.8 0.3 0.00038 20.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK60401.1 - 1.1e-05 25.3 0.0 5.4e-05 23.1 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KIK60401.1 - 2.7e-05 23.7 0.0 0.13 11.7 0.2 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK60401.1 - 0.00039 21.0 0.1 0.00072 20.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK60401.1 - 0.0018 18.0 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK60401.1 - 0.0043 17.5 0.0 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK60401.1 - 0.0061 16.8 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KIK60401.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KIK60401.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK60401.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_27 PF13514.6 KIK60401.1 - 0.044 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KIK60401.1 - 0.047 13.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.7 KIK60401.1 - 0.05 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 KIK60401.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KIK60401.1 - 0.055 13.4 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain HMG_box PF00505.19 KIK60403.1 - 0.016 15.6 0.1 0.037 14.4 0.1 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box RhoGAP PF00620.27 KIK60405.1 - 1.6e-10 41.0 0.1 5.6e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KIK60405.1 - 1.6e-08 34.5 0.0 3.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KIK60405.1 - 5.7e-07 29.7 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain PX PF00787.24 KIK60406.1 - 9.3e-19 67.5 0.0 1.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KIK60406.1 - 3.6e-16 59.3 0.0 1.8e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 KIK60406.1 - 1.3e-06 27.9 0.0 2.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Sugar_tr PF00083.24 KIK60407.1 - 3.8e-88 296.3 28.5 4.3e-88 296.2 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK60407.1 - 2.5e-35 122.0 26.3 2.5e-35 122.0 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ERCC4 PF02732.15 KIK60408.1 - 6.7e-19 68.6 0.0 1.7e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 ERCC4 domain MOZART1 PF12554.8 KIK60410.1 - 3.1e-26 90.9 0.5 3.8e-26 90.6 0.5 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated XPC-binding PF09280.11 KIK60410.1 - 0.013 15.3 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 XPC-binding domain Zds_C PF08632.10 KIK60411.1 - 8.8e-29 99.0 0.9 1.6e-28 98.2 0.9 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term STE3 PF02076.15 KIK60413.1 - 1.3e-65 221.5 12.4 1.6e-65 221.2 12.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pkinase PF00069.25 KIK60414.1 - 6.4e-25 88.0 0.0 8.8e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60414.1 - 2.8e-06 26.8 0.0 1.7e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KIK60414.1 - 0.083 12.8 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tma16 PF11176.8 KIK60415.1 - 8.4e-44 149.0 2.0 1.1e-43 148.6 2.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 SF3b1 PF08920.10 KIK60417.1 - 3.8e-21 75.8 1.9 3.8e-21 75.8 1.9 2.5 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KIK60417.1 - 8.5e-10 38.9 9.6 0.012 16.0 0.1 7.6 4 2 3 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 KIK60417.1 - 1.6e-08 34.9 7.8 0.013 16.0 0.0 7.6 9 1 1 10 10 10 2 HEAT-like repeat HEAT PF02985.22 KIK60417.1 - 7.5e-08 32.0 11.7 0.06 13.6 0.1 9.7 12 0 0 12 12 10 1 HEAT repeat Adaptin_N PF01602.20 KIK60417.1 - 4.2e-07 28.9 1.1 0.036 12.6 0.0 3.3 3 0 0 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KIK60417.1 - 1.1e-06 29.1 1.4 1.2 9.8 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIK60417.1 - 2.6e-05 24.3 8.7 0.53 10.3 0.0 6.5 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 KIK60417.1 - 6.1e-05 22.8 0.7 2 8.0 0.0 4.9 4 1 1 5 5 5 2 NUC173 domain UME PF08064.13 KIK60417.1 - 0.0004 20.2 0.3 0.8 9.6 0.0 4.8 5 2 2 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 KIK60417.1 - 0.00067 19.3 1.7 1.5 8.3 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal DUF3110 PF11360.8 KIK60417.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 KIK60417.1 - 0.12 11.5 2.0 4.3 6.4 0.0 3.4 4 0 0 4 4 4 0 Dopey, N-terminal dsrm PF00035.26 KIK60418.1 - 1.3e-07 32.2 0.0 2.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KIK60418.1 - 3.2e-06 27.3 0.0 5.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK60418.1 - 0.029 15.0 0.0 0.065 13.9 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease III domain zf_CCCH_4 PF18345.1 KIK60419.1 - 1.2e-27 95.0 63.1 8.8e-06 25.6 0.8 6.4 6 0 0 6 6 6 6 Zinc finger domain zf-CCCH PF00642.24 KIK60419.1 - 1.2e-26 92.0 43.3 7.1e-06 25.8 0.8 6.5 6 0 0 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK60419.1 - 8.2e-23 79.7 51.0 2.3e-06 27.3 5.8 6.6 6 0 0 6 6 6 5 CCCH-type zinc finger Torus PF16131.5 KIK60419.1 - 1.9e-15 57.5 34.5 0.00011 22.9 0.0 6.8 5 1 2 7 7 6 5 Torus domain RRM_1 PF00076.22 KIK60419.1 - 3.5e-11 42.7 0.0 0.011 15.5 0.0 4.6 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 KIK60419.1 - 1e-07 32.1 49.8 0.1 13.1 1.7 6.5 6 0 0 6 6 6 6 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIK60419.1 - 6.9e-07 29.5 25.6 1.6e-05 25.0 8.0 5.4 4 1 1 5 5 5 2 Zinc-finger containing family IBR PF01485.21 KIK60419.1 - 1.4e-06 28.5 17.2 3.2e-06 27.3 7.7 2.6 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIK60419.1 - 1.5e-05 24.8 2.9 1.5e-05 24.8 2.9 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK60419.1 - 0.0015 18.8 1.7 0.0015 18.8 1.7 3.7 4 0 0 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK60419.1 - 0.0028 17.5 2.2 0.0028 17.5 2.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK60419.1 - 0.031 14.3 5.1 0.03 14.3 1.6 2.8 2 0 0 2 2 2 0 RING-type zinc-finger CHASE8 PF17152.4 KIK60419.1 - 0.031 14.5 0.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Periplasmic sensor domain SPOR PF05036.13 KIK60419.1 - 0.036 14.5 0.1 1.7 9.1 0.0 2.8 3 0 0 3 3 3 0 Sporulation related domain Adaptin_N PF01602.20 KIK60420.1 - 3.2e-144 481.4 8.3 3.7e-144 481.1 8.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KIK60420.1 - 7.1e-22 77.8 0.3 1.6e-21 76.7 0.3 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KIK60420.1 - 4.8e-07 30.0 9.5 7.1e-06 26.1 0.3 3.8 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK60420.1 - 0.0015 18.8 3.4 0.93 9.9 0.1 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KIK60420.1 - 0.002 18.2 0.6 37 5.0 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat MMS19_N PF14500.6 KIK60420.1 - 0.016 14.8 0.4 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RICTOR_M PF14666.6 KIK60420.1 - 0.07 12.9 0.1 0.42 10.4 0.0 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain NopRA1 PF16201.5 KIK60420.1 - 0.086 12.4 0.1 3.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Peptidase_M73 PF12389.8 KIK60420.1 - 0.089 12.6 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Myb_DNA-bind_6 PF13921.6 KIK60421.1 - 2.4e-39 133.4 7.5 2.4e-15 56.5 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK60421.1 - 2.7e-39 133.1 9.3 6.8e-16 58.2 0.6 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 KIK60421.1 - 0.00015 21.8 1.2 0.42 10.7 0.4 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 KIK60421.1 - 0.00033 20.8 0.7 0.1 12.8 0.2 2.8 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 KIK60421.1 - 0.00038 20.6 0.0 0.63 10.3 0.0 3.8 4 0 0 4 4 4 1 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 KIK60421.1 - 0.0012 18.7 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 KIK60421.1 - 0.014 15.4 0.0 1.1 9.3 0.0 2.6 2 1 1 3 3 3 0 SLIDE Melibiase_2 PF16499.5 KIK60422.1 - 1.1e-21 77.3 0.9 4.9e-11 42.3 1.2 2.1 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIK60422.1 - 1.7e-09 37.6 0.2 3.6e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 KIK60422.1 - 0.045 13.0 0.0 0.18 11.1 0.0 1.9 1 1 0 1 1 1 0 Glycoside hydrolase 97 Usp PF00582.26 KIK60423.1 - 9.3e-13 48.9 0.0 1.3e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family ABC_tran PF00005.27 KIK60425.1 - 6.7e-28 97.9 0.0 2.2e-27 96.2 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK60425.1 - 3.6e-09 36.9 0.1 0.0021 17.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK60425.1 - 4.8e-07 29.4 0.0 0.018 14.4 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK60425.1 - 1.5e-05 24.9 0.0 0.0011 18.7 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIK60425.1 - 0.0005 20.6 0.1 0.00088 19.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK60425.1 - 0.00062 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK60425.1 - 0.0035 17.6 0.0 0.031 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK60425.1 - 0.0057 17.1 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KIK60425.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KIK60425.1 - 0.026 14.3 0.0 0.069 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KIK60425.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK60425.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KIK60425.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Polysacc_deac_1 PF01522.21 KIK60426.1 - 8.8e-28 96.7 0.0 1.4e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIK60426.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SSP160 PF06933.11 KIK60426.1 - 0.071 11.3 14.5 0.11 10.7 14.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pox_A12 PF04651.13 KIK60426.1 - 0.089 12.8 1.0 0.15 12.1 1.0 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Sporozoite_P67 PF05642.11 KIK60426.1 - 0.16 10.0 4.2 0.22 9.6 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GMC_oxred_N PF00732.19 KIK60427.1 - 1.7e-58 198.4 0.0 2.2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK60427.1 - 1.7e-27 96.7 0.0 2.6e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK60427.1 - 0.00017 21.7 0.1 0.00086 19.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK60427.1 - 0.00029 20.2 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK60427.1 - 0.0021 17.2 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KIK60427.1 - 0.0078 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK60427.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK60427.1 - 0.021 14.0 0.0 0.079 12.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KIK60427.1 - 0.066 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMN_red PF03358.15 KIK60428.1 - 2.2e-10 40.5 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIK60428.1 - 1.3e-05 25.0 0.0 1.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KIK60428.1 - 0.028 14.6 0.2 0.34 11.1 0.2 2.2 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.7 KIK60428.1 - 0.039 14.2 0.0 0.071 13.3 0.0 1.4 1 1 0 1 1 1 0 Flavodoxin domain Carb_anhydrase PF00194.21 KIK60429.1 - 1.7e-23 83.5 0.0 1.3e-21 77.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase FSH1 PF03959.13 KIK60430.1 - 7.5e-51 172.8 0.0 8.6e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KIK60430.1 - 1.9e-05 24.6 0.0 0.063 13.1 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KIK60430.1 - 0.0011 18.7 0.0 4.6 6.8 0.0 3.1 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK60430.1 - 0.0014 19.3 0.0 0.006 17.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KIK60430.1 - 0.13 11.8 0.0 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 PE-PPE domain Dynein_light PF01221.18 KIK60431.1 - 1.8e-39 133.9 0.8 2.1e-39 133.7 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DcpS PF05652.12 KIK60432.1 - 1.4e-09 38.7 0.0 1.6e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KIK60433.1 - 1.2e-23 83.8 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KIK60433.1 - 0.00043 21.1 0.3 0.00075 20.3 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Myb_DNA-binding PF00249.31 KIK60434.1 - 3.9e-41 139.0 10.4 7.9e-14 51.6 0.5 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK60434.1 - 1.4e-29 102.1 3.0 4.3e-14 52.5 0.2 3.2 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIK60434.1 - 1e-07 31.7 0.2 0.0012 18.7 0.0 3.1 3 1 0 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KIK60434.1 - 0.0021 18.2 3.3 0.14 12.3 0.1 3.1 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 KIK60434.1 - 0.0053 17.1 4.8 0.24 11.8 0.3 3.3 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KIK60434.1 - 0.0086 16.4 2.7 0.73 10.2 0.1 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KIK60434.1 - 0.032 14.3 0.6 12 6.0 0.0 2.9 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3606 PF12244.8 KIK60434.1 - 0.094 12.7 0.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) PriCT_2 PF08707.11 KIK60434.1 - 0.71 10.3 5.2 0.49 10.8 0.4 2.8 2 1 1 3 3 3 0 Primase C terminal 2 (PriCT-2) GST_C PF00043.25 KIK60435.1 - 1.6e-11 44.2 0.0 1.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK60435.1 - 0.0016 18.6 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ACC_central PF08326.12 KIK60436.1 - 2.7e-245 816.1 0.0 3.7e-245 815.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KIK60436.1 - 8.7e-169 562.3 0.0 1.1e-168 561.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KIK60436.1 - 1.8e-51 174.6 0.0 3.5e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIK60436.1 - 6.6e-29 100.7 0.1 1.6e-28 99.4 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK60436.1 - 5.7e-21 74.7 0.0 8.6e-20 70.9 0.0 2.8 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIK60436.1 - 4.5e-16 58.4 0.0 9.6e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KIK60436.1 - 0.002 18.2 0.0 0.0063 16.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIK60436.1 - 0.018 14.6 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIK60436.1 - 0.019 14.5 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIK60436.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Ig_C17orf99 PF17736.1 KIK60436.1 - 0.16 12.0 0.0 0.55 10.3 0.0 1.9 1 0 0 1 1 1 0 C17orf99 Ig domain FAD_binding_3 PF01494.19 KIK60437.1 - 1.3e-21 77.3 0.0 1.7e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK60437.1 - 1.4e-05 25.2 0.5 3.9e-05 23.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK60437.1 - 0.0001 21.7 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK60437.1 - 0.00039 19.4 0.1 0.0057 15.5 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 KIK60437.1 - 0.0017 18.0 0.8 0.0073 15.9 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KIK60437.1 - 0.016 14.3 0.0 0.041 12.9 0.0 1.6 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 KIK60437.1 - 0.018 14.1 1.0 0.034 13.2 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIK60437.1 - 0.14 10.8 0.2 0.23 10.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK60437.1 - 0.15 11.3 0.0 0.44 9.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK60437.1 - 0.16 12.0 0.0 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding CN_hydrolase PF00795.22 KIK60438.1 - 1.4e-39 136.0 0.0 2.1e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KIK60438.1 - 3.7e-23 81.9 0.0 3.5e-22 78.7 0.0 2.3 2 1 0 2 2 2 1 NAD synthase PBP1_TM PF14812.6 KIK60439.1 - 0.092 13.1 10.9 1.6 9.1 4.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 KIK60439.1 - 0.16 13.0 9.8 0.076 14.0 3.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM176 PF14851.6 KIK60439.1 - 1.9 8.2 7.9 0.89 9.2 2.0 2.1 2 0 0 2 2 2 0 FAM176 family RRM_1 PF00076.22 KIK60441.1 - 2.1e-08 33.8 0.0 5.3e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1e PF01406.19 KIK60442.1 - 3.7e-130 433.7 0.4 6e-130 433.0 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KIK60442.1 - 1.3e-07 30.7 0.8 0.0001 21.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIK60442.1 - 8.6e-06 24.3 0.9 0.00066 18.0 0.0 3.0 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KIK60442.1 - 0.00063 20.2 0.0 0.00063 20.2 0.0 2.6 3 0 0 3 3 3 1 DALR domain tRNA-synt_1c PF00749.21 KIK60442.1 - 0.13 11.1 0.9 0.45 9.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF4230 PF14014.6 KIK60442.1 - 4.4 7.6 6.1 10 6.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4230) HNH_2 PF13391.6 KIK60445.1 - 1e-09 38.4 0.0 2.2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF808 PF05661.12 KIK60446.1 - 0.054 12.6 0.0 0.062 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) HALZ PF02183.18 KIK60449.1 - 0.026 14.7 3.1 0.05 13.8 1.6 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper FUSC PF04632.12 KIK60449.1 - 0.048 12.2 3.7 0.062 11.8 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.13 KIK60449.1 - 0.054 13.6 4.9 5.7 7.0 0.1 3.3 3 0 0 3 3 3 0 DivIVA protein Hemerythrin PF01814.23 KIK60449.1 - 0.087 13.4 5.7 0.36 11.5 0.5 2.9 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Phage_Mu_Gam PF07352.12 KIK60449.1 - 0.14 12.1 0.8 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF5082 PF16888.5 KIK60449.1 - 0.22 11.8 5.2 0.31 11.3 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) MutS_III PF05192.18 KIK60449.1 - 0.27 11.4 8.2 0.12 12.6 5.7 1.7 1 1 0 1 1 1 0 MutS domain III Seryl_tRNA_N PF02403.22 KIK60449.1 - 0.5 10.6 5.3 1.8 8.8 0.3 3.5 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KIK60449.1 - 0.83 9.7 3.9 11 6.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 KIK60449.1 - 1 7.9 3.5 7.8 5.0 0.1 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A GAS PF13851.6 KIK60449.1 - 1.3 8.3 7.8 1.5 8.2 1.6 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CREPT PF16566.5 KIK60449.1 - 2 8.6 7.7 0.8 9.9 2.9 2.3 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Cep57_MT_bd PF06657.13 KIK60449.1 - 2.2 8.8 9.5 0.29 11.6 0.5 3.2 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.10 KIK60449.1 - 3.4 7.8 5.6 4.6 7.4 2.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1614 PF07758.11 KIK60450.1 - 0.075 13.0 0.0 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) Peptidase_M20 PF01546.28 KIK60455.1 - 1.6e-24 86.8 0.0 2.5e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK60455.1 - 1.4e-14 53.9 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-H2C2_2 PF13465.6 KIK60456.1 - 5.9e-20 70.7 51.4 1.9e-06 28.0 0.3 8.5 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK60456.1 - 5.5e-18 64.1 40.8 0.00033 21.3 1.1 8.9 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK60456.1 - 2.1e-17 62.5 67.9 6.8e-06 26.3 1.3 10.4 11 1 0 11 11 10 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK60456.1 - 6.4e-08 32.7 12.5 0.0081 16.4 0.3 5.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KIK60456.1 - 9.4e-07 29.4 42.0 0.0021 18.7 2.1 7.7 3 2 4 7 7 7 4 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KIK60456.1 - 7.7e-05 22.4 1.0 7.7e-05 22.4 1.0 5.4 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIK60456.1 - 0.00061 19.7 29.1 0.16 12.0 1.1 7.2 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIK60456.1 - 0.027 14.8 23.2 0.73 10.2 7.3 4.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 KIK60456.1 - 0.11 12.6 0.3 0.11 12.6 0.3 5.5 6 0 0 6 6 6 0 Zic proteins zinc finger domain zf-met PF12874.7 KIK60456.1 - 0.37 11.2 20.3 1.2 9.6 1.6 5.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KIK60456.1 - 4.1 7.4 16.8 2.6 8.0 0.1 5.7 6 0 0 6 6 6 0 zinc-finger of a C2HC-type CTP_transf_like PF01467.26 KIK60457.1 - 6.8e-18 65.2 0.0 9.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like P34-Arc PF04045.14 KIK60458.1 - 2.4e-108 361.4 0.1 2.8e-108 361.2 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Tweety PF04906.13 KIK60458.1 - 0.022 13.5 0.1 0.03 13.0 0.1 1.1 1 0 0 1 1 1 0 Tweety Pkinase PF00069.25 KIK60459.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK60459.1 - 2.4e-36 125.4 0.0 4e-36 124.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK60459.1 - 1.8e-07 30.4 0.3 2.8e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KIK60459.1 - 0.004 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK60459.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KIK60459.1 - 0.024 14.6 0.4 0.057 13.3 0.2 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK60459.1 - 0.03 13.9 0.2 0.047 13.3 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DNA_ligase_A_M PF01068.21 KIK60460.1 - 9.1e-52 175.7 0.1 2.5e-51 174.2 0.1 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK60460.1 - 4.3e-40 137.9 0.2 9.7e-40 136.7 0.1 1.7 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KIK60460.1 - 4.7e-21 75.0 0.0 1.9e-10 41.0 0.0 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KIK60460.1 - 1.9e-14 54.3 1.2 4.8e-13 49.7 0.2 2.6 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 KIK60460.1 - 1.7e-13 51.0 0.8 5e-13 49.5 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KIK60460.1 - 8.8e-07 29.2 0.0 0.069 13.5 0.0 3.1 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIK60460.1 - 0.0068 16.3 0.0 0.14 12.2 0.0 2.8 3 0 0 3 3 3 1 twin BRCT domain Forkhead PF00250.18 KIK60461.1 - 1.9e-25 88.9 0.0 3.7e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain AICARFT_IMPCHas PF01808.18 KIK60462.1 - 5.7e-89 298.5 0.0 7.4e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KIK60462.1 - 3e-24 85.0 0.0 5.4e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain MTS PF05175.14 KIK60464.1 - 3e-07 30.2 0.0 2e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Pkinase PF00069.25 KIK60467.1 - 1.2e-06 28.1 0.0 1.2e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK60467.1 - 3.2e-06 26.7 0.2 3.2e-06 26.7 0.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK60467.1 - 4.3e-06 26.8 0.1 4.3e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK60467.1 - 0.00037 20.1 0.2 0.00041 20.0 0.2 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIK60467.1 - 0.01 15.4 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK60467.1 - 0.011 15.1 0.1 0.012 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK60467.1 - 0.013 14.4 0.0 0.013 14.4 0.0 1.0 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK60467.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIK60467.1 - 0.2 10.9 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like HEAT PF02985.22 KIK60469.1 - 9.4e-16 56.6 11.8 0.049 13.9 0.1 10.5 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 KIK60469.1 - 1.3e-12 48.0 18.2 0.00013 22.4 0.1 11.0 12 1 1 13 13 12 1 HEAT-like repeat HEAT_2 PF13646.6 KIK60469.1 - 2.4e-11 43.9 6.6 0.56 10.6 0.0 9.1 6 2 4 11 11 11 3 HEAT repeats Cnd1 PF12717.7 KIK60469.1 - 9.1e-08 32.3 0.1 0.0031 17.6 0.0 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KIK60469.1 - 4.8e-07 29.6 0.3 5.3e-06 26.3 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KIK60469.1 - 2.6e-06 27.5 3.0 3.6 7.5 0.1 7.9 7 3 3 10 10 10 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 KIK60469.1 - 8.8e-06 25.6 0.1 0.36 10.6 0.1 4.5 3 2 0 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 KIK60469.1 - 1.5e-05 25.1 1.5 0.023 14.8 0.0 4.6 4 1 0 4 4 3 1 Exportin 1-like protein IFRD PF05004.13 KIK60469.1 - 2.2e-05 23.7 1.5 0.1 11.7 0.0 4.1 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 KIK60469.1 - 9.4e-05 22.1 0.4 0.63 9.6 0.0 5.1 5 1 1 6 6 6 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 KIK60469.1 - 0.00041 20.9 0.1 0.61 10.7 0.0 4.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KIK60469.1 - 0.0074 15.5 7.9 5.1 6.1 0.0 5.8 7 1 1 8 8 8 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KIK60469.1 - 0.029 14.5 0.3 57 3.9 0.0 4.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KIK60469.1 - 0.043 13.3 0.1 5.4 6.5 0.1 3.8 4 0 0 4 4 4 0 Tti2 family Cohesin_HEAT PF12765.7 KIK60469.1 - 0.11 12.9 0.1 0.82 10.0 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion He_PIG PF05345.12 KIK60470.1 - 3.6e-08 33.4 3.4 3.6e-08 33.4 3.4 4.9 6 0 0 6 6 6 1 Putative Ig domain FAD_binding_3 PF01494.19 KIK60472.1 - 2.7e-17 63.1 0.6 3.2e-07 29.9 0.1 2.9 1 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK60472.1 - 5.2e-06 25.8 0.1 0.0009 18.4 0.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 KIK60472.1 - 3.9e-05 22.9 0.0 6.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KIK60472.1 - 0.0031 17.2 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK60472.1 - 0.0044 15.9 0.1 0.06 12.2 0.2 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KIK60472.1 - 0.0048 16.2 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK60472.1 - 0.0054 16.0 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK60472.1 - 0.023 15.3 0.3 0.14 12.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK60472.1 - 0.03 14.3 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK60472.1 - 0.19 12.0 1.6 0.33 11.2 0.3 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sec6 PF06046.13 KIK60473.1 - 1.5e-148 495.8 6.9 1.5e-148 495.8 6.9 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Fes1 PF08609.10 KIK60473.1 - 0.12 13.3 2.2 0.35 11.8 0.1 3.0 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 Dynein_light PF01221.18 KIK60473.1 - 1 9.7 5.0 4.6 7.6 1.5 3.2 2 0 0 2 2 2 0 Dynein light chain type 1 GIT1_C PF12205.8 KIK60474.1 - 0.062 13.4 1.9 0.094 12.8 1.9 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Sox_N PF12444.8 KIK60474.1 - 0.083 14.0 0.9 0.28 12.3 0.2 2.1 2 0 0 2 2 2 0 Sox developmental protein N terminal DUF948 PF06103.11 KIK60474.1 - 0.11 12.7 0.2 1.4 9.2 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 KIK60474.1 - 0.11 11.0 0.4 0.13 10.8 0.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family baeRF_family12 PF18856.1 KIK60474.1 - 0.58 10.7 5.3 1.7 9.2 0.2 2.5 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 ISG65-75 PF11727.8 KIK60474.1 - 0.64 9.2 5.3 1.3 8.2 5.0 1.5 1 1 1 2 2 2 0 Invariant surface glycoprotein Ku_C PF03730.14 KIK60474.1 - 1.3 9.8 5.6 0.7 10.6 2.4 2.1 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Nup35_RRM PF05172.13 KIK60476.1 - 3.1e-07 30.3 0.0 1.2e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KIK60476.1 - 8.4e-05 22.5 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif AIP3 PF03915.13 KIK60478.1 - 1e-149 499.1 5.0 1.7e-149 498.4 5.0 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4834 PF16118.5 KIK60478.1 - 0.17 12.9 0.3 0.86 10.6 0.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Fib_alpha PF08702.10 KIK60478.1 - 1.5 9.0 13.7 11 6.2 0.7 4.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KIK60478.1 - 1.6 9.2 13.5 0.061 13.8 2.6 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 KIK60478.1 - 1.7 9.3 11.3 8.3 7.0 3.3 4.2 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Syntaxin PF00804.25 KIK60478.1 - 2.2 7.9 17.8 0.24 11.0 2.0 3.8 3 1 1 4 4 4 0 Syntaxin LPP PF04728.13 KIK60478.1 - 2.3 8.6 6.9 68 4.0 2.3 3.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper OmpH PF03938.14 KIK60478.1 - 3.2 8.1 15.8 0.27 11.6 1.4 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DMPK_coil PF08826.10 KIK60478.1 - 7 6.8 8.1 4 7.6 0.2 3.6 4 0 0 4 4 4 0 DMPK coiled coil domain like DUF5082 PF16888.5 KIK60478.1 - 7.7 6.8 10.4 9.7 6.5 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF1772 PF08592.11 KIK60480.1 - 0.78 10.1 5.0 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KIK60481.1 - 4.9e-39 134.2 41.6 4.8e-36 124.4 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4212 PF13937.6 KIK60481.1 - 0.035 14.5 0.7 0.035 14.5 0.7 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF4212) DUF3367 PF11847.8 KIK60481.1 - 0.34 8.7 3.2 0.49 8.2 3.2 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase NACHT PF05729.12 KIK60482.1 - 0.0019 18.1 0.1 0.0048 16.8 0.1 1.7 2 0 0 2 2 2 1 NACHT domain Adenosine_kin PF04008.14 KIK60482.1 - 0.058 13.2 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Adenosine specific kinase PhoH PF02562.16 KIK60482.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Ank_4 PF13637.6 KIK60483.1 - 7.3e-29 99.8 6.7 1.3e-05 25.7 0.5 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK60483.1 - 6.8e-26 90.7 16.9 4.9e-13 49.5 5.1 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60483.1 - 3.5e-22 77.8 30.4 0.00037 20.8 0.8 6.9 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KIK60483.1 - 2e-20 70.7 14.9 0.0039 17.6 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KIK60483.1 - 6.1e-05 23.2 14.0 0.24 11.8 0.7 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Mic1 PF07035.12 KIK60483.1 - 0.00011 21.9 3.2 2.9 7.6 0.0 5.1 2 1 3 5 5 5 1 Colon cancer-associated protein Mic1-like FLgD_tudor PF13861.6 KIK60483.1 - 0.0018 18.5 0.0 2.3 8.5 0.2 3.6 2 2 0 2 2 2 2 FlgD Tudor-like domain YajC PF02699.15 KIK60483.1 - 0.041 13.8 5.9 32 4.5 0.0 5.1 1 1 5 6 6 6 0 Preprotein translocase subunit DUF555 PF04475.12 KIK60483.1 - 0.083 13.2 6.5 20 5.5 0.0 4.5 2 1 4 6 6 6 0 Protein of unknown function (DUF555) Amidinotransf PF02274.17 KIK60483.1 - 0.091 11.8 0.5 0.38 9.8 0.2 2.1 1 1 0 1 1 1 0 Amidinotransferase NdhO PF11910.8 KIK60483.1 - 0.1 12.8 1.0 63 3.9 0.0 4.1 4 1 1 5 5 5 0 Cyanobacterial and plant NDH-1 subunit O tRNA_anti_2 PF13742.6 KIK60483.1 - 0.24 11.6 0.9 6.1 7.1 0.0 3.2 2 1 1 3 3 3 0 OB-fold nucleic acid binding domain Arg_repressor PF01316.21 KIK60483.1 - 0.82 9.5 9.6 56 3.6 0.1 5.4 6 0 0 6 6 6 0 Arginine repressor, DNA binding domain Melibiase_2 PF16499.5 KIK60484.1 - 2.2e-15 56.6 1.7 1.1e-07 31.3 1.4 2.2 1 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIK60484.1 - 1.1e-09 38.2 0.1 2.5e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 KIK60484.1 - 0.0095 15.2 0.0 0.075 12.3 0.0 2.0 1 1 0 1 1 1 1 Glycoside hydrolase 97 Aminotran_1_2 PF00155.21 KIK60485.1 - 7.5e-22 78.0 0.0 9e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIK60485.1 - 1.3e-08 34.1 0.0 3.3e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Glyco_hydro_16 PF00722.21 KIK60486.1 - 4.9e-24 84.8 0.3 6.5e-24 84.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.32 KIK60487.1 - 5.3e-102 330.9 62.0 1.1e-10 41.9 0.1 14.8 14 0 0 14 14 14 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK60487.1 - 1.9e-32 111.4 5.8 0.013 15.8 0.0 11.8 2 2 9 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK60487.1 - 2.6e-21 76.0 9.0 0.0022 17.0 0.0 10.8 2 2 8 11 11 11 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK60487.1 - 4.8e-13 48.3 0.0 0.012 14.0 0.0 6.1 2 1 5 7 7 7 4 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK60487.1 - 2.9e-12 46.2 15.3 1.4 8.9 0.1 10.9 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK60487.1 - 1.4e-07 31.6 0.0 3.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KIK60487.1 - 2e-05 24.1 0.1 1.9 7.8 0.0 4.8 4 1 0 4 4 4 1 WD40-like domain AAA_16 PF13191.6 KIK60487.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK60487.1 - 0.0093 15.9 3.1 0.26 11.3 0.0 4.4 5 0 0 5 5 5 1 PQQ enzyme repeat APS_kinase PF01583.20 KIK60487.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK60487.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KIK60487.1 - 0.14 11.3 0.1 0.46 9.6 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain Ribosomal_L23 PF00276.20 KIK60488.1 - 5.4e-11 42.7 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Metallophos PF00149.28 KIK60489.1 - 2e-14 54.6 0.1 4.1e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF953 PF06110.11 KIK60489.1 - 0.057 13.0 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) BTB PF00651.31 KIK60491.1 - 0.0045 17.2 0.1 0.0092 16.2 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain p450 PF00067.22 KIK60492.1 - 2.4e-66 224.4 0.0 6e-34 117.6 0.1 2.5 2 1 0 2 2 2 2 Cytochrome P450 DHO_dh PF01180.21 KIK60493.1 - 6.7e-96 321.0 0.0 8.1e-96 320.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KIK60493.1 - 0.01 14.9 0.1 0.071 12.1 0.3 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KIK60493.1 - 0.063 12.7 0.3 0.16 11.3 0.2 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase SAM_Ste50p PF09235.10 KIK60493.1 - 0.079 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Velvet PF11754.8 KIK60494.1 - 1.2e-35 123.7 0.0 1.7e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor 4HBT PF03061.22 KIK60496.1 - 0.00082 19.7 0.1 0.0016 18.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KIK60496.1 - 0.061 13.5 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) HMG_box PF00505.19 KIK60497.1 - 9e-13 48.4 2.1 1.6e-12 47.7 2.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK60497.1 - 7.2e-11 42.5 3.1 1.4e-10 41.6 3.1 1.4 1 0 0 1 1 1 1 HMG-box domain GramPos_pilinD1 PF16555.5 KIK60497.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain Peptidase_C14 PF00656.22 KIK60498.1 - 9.3e-05 22.5 0.0 0.00021 21.3 0.0 1.6 2 0 0 2 2 2 1 Caspase domain Peptidase_C13 PF01650.18 KIK60498.1 - 0.00044 19.9 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family zf-RING_UBOX PF13445.6 KIK60499.1 - 2e-08 34.1 0.5 4.9e-08 32.9 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK60499.1 - 2.6e-07 30.5 0.5 5.7e-07 29.4 0.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK60499.1 - 5.9e-07 29.2 0.6 5.9e-07 29.2 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK60499.1 - 2e-06 27.9 0.7 2e-06 27.9 0.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KIK60499.1 - 3e-05 23.8 0.9 0.0051 16.6 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK60499.1 - 4.6e-05 23.2 2.1 0.00018 21.3 2.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK60499.1 - 0.00027 21.2 5.9 0.0021 18.4 5.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 KIK60499.1 - 0.00069 19.4 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIK60499.1 - 0.033 14.1 1.2 0.4 10.6 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 GD_AH_C PF04295.13 KIK60499.1 - 0.067 12.0 0.3 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus HAP1_N PF04849.13 KIK60499.1 - 0.069 12.3 7.2 0.13 11.4 7.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region MMADHC PF10229.9 KIK60499.1 - 0.18 11.5 2.8 0.3 10.8 2.8 1.3 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein DUF883 PF05957.13 KIK60499.1 - 0.33 11.6 3.7 4.7 7.9 0.0 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2570 PF10828.8 KIK60499.1 - 0.71 9.7 5.2 1.2 9.0 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) zf-RING_11 PF17123.5 KIK60499.1 - 0.77 9.6 2.7 1.6 8.5 2.7 1.5 1 0 0 1 1 1 0 RING-like zinc finger FAM76 PF16046.5 KIK60499.1 - 0.84 8.9 9.7 1.3 8.3 9.7 1.3 1 0 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 KIK60499.1 - 0.95 8.6 4.3 1.6 7.9 4.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 KIK60499.1 - 2.6 8.6 9.8 6.2 7.4 9.8 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-RING_4 PF14570.6 KIK60499.1 - 9.6 6.1 6.2 1.1e+02 2.7 6.2 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Arginosuc_synth PF00764.19 KIK60500.1 - 9.4e-156 519.0 0.0 1.1e-155 518.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KIK60500.1 - 0.00048 19.7 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIK60500.1 - 0.012 14.4 0.0 0.026 13.3 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase Pro-kuma_activ PF09286.11 KIK60501.1 - 3.2e-35 121.5 0.2 2.2e-34 118.8 0.1 2.2 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK60501.1 - 1.8e-05 24.1 0.6 1.8e-05 24.1 0.6 1.9 2 0 0 2 2 2 1 Subtilase family PTS_2-RNA PF01885.16 KIK60502.1 - 5.5e-21 75.4 0.0 6.9e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family SIR2 PF02146.17 KIK60503.1 - 4.4e-62 209.1 0.0 6.7e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KIK60503.1 - 1.3e-06 28.3 0.3 5.1e-05 23.1 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KIK60503.1 - 0.0061 16.3 0.2 1.9 8.2 0.0 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Histone PF00125.24 KIK60505.1 - 2.9e-46 157.1 5.8 6.8e-46 155.9 5.8 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK60505.1 - 3e-05 24.3 0.1 4.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK60505.1 - 7e-05 22.9 0.1 0.00012 22.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK60505.1 - 0.00083 19.6 0.1 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIK60505.1 - 0.0081 16.8 3.1 0.012 16.2 3.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIK60505.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KIK60506.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK60506.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK60506.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK60506.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK60506.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK60506.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Nucleopor_Nup85 PF07575.13 KIK60507.1 - 3.4e-59 200.9 0.0 4.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin RhoGAP PF00620.27 KIK60508.1 - 7.1e-49 165.5 0.2 1.9e-48 164.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KIK60508.1 - 2.3e-14 53.4 0.9 1.6e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PCRF PF03462.18 KIK60508.1 - 6.1e-05 23.0 4.1 0.00011 22.1 2.5 2.1 2 0 0 2 2 2 1 PCRF domain PspA_IM30 PF04012.12 KIK60508.1 - 0.015 14.9 6.2 0.033 13.8 6.2 1.5 1 0 0 1 1 1 0 PspA/IM30 family TBCA PF02970.16 KIK60508.1 - 0.034 14.5 8.3 0.027 14.8 5.5 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A Golgin_A5 PF09787.9 KIK60508.1 - 0.054 12.9 6.6 0.079 12.4 5.5 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF5344 PF17279.2 KIK60508.1 - 0.068 13.8 2.9 4 8.1 2.6 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Baculo_PEP_C PF04513.12 KIK60508.1 - 0.077 13.0 3.1 10 6.1 0.5 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KIK60508.1 - 0.09 12.8 1.6 5.3 7.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Topo_Zn_Ribbon PF08272.11 KIK60508.1 - 0.098 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Fib_alpha PF08702.10 KIK60508.1 - 0.11 12.7 5.8 0.069 13.3 3.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KIK60508.1 - 0.41 10.7 3.2 1.6 8.9 1.9 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA2 PF16740.5 KIK60508.1 - 0.44 10.3 3.8 0.56 10.0 1.9 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FapA PF03961.13 KIK60508.1 - 0.48 9.0 5.0 0.51 8.9 4.0 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A ApoLp-III PF07464.11 KIK60508.1 - 0.56 10.3 3.8 0.93 9.6 2.3 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TMPIT PF07851.13 KIK60508.1 - 0.65 9.2 4.2 1.3 8.2 4.2 1.5 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 KIK60508.1 - 1.2 7.9 9.0 0.76 8.6 7.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KIK60508.1 - 3.6 7.1 8.2 0.47 10.0 3.9 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit IFT20 PF14931.6 KIK60508.1 - 4.1 7.6 8.0 6.8 6.9 7.0 2.0 2 1 0 2 2 1 0 Intraflagellar transport complex B, subunit 20 DUF4407 PF14362.6 KIK60508.1 - 8.9 5.6 7.6 17 4.6 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 KIK60509.1 - 2e-08 34.0 0.1 7.2e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK60509.1 - 3.5e-05 23.6 0.0 0.0015 18.3 0.0 3.1 2 2 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIK60509.1 - 0.13 12.1 0.6 0.5 10.3 0.0 2.2 2 1 1 3 3 3 0 F-box CENP-T_C PF15511.6 KIK60510.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK60510.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK60510.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK60510.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK60510.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK60510.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KIK60511.1 - 3.2e-48 163.4 1.8 4.2e-48 163.0 1.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK60511.1 - 3.1e-05 24.3 0.1 4.8e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK60511.1 - 7e-05 22.9 0.1 0.00012 22.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK60511.1 - 0.00091 19.5 0.1 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIK60511.1 - 0.0026 18.3 1.8 0.0036 17.9 1.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIK60511.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Asp PF00026.23 KIK60512.1 - 1.2e-67 228.6 4.2 1.7e-67 228.1 4.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK60512.1 - 8.7e-12 45.6 1.5 4e-09 37.0 1.5 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ChiC PF06483.11 KIK60512.1 - 0.03 14.3 0.2 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 Chitinase C Asp_protease_2 PF13650.6 KIK60512.1 - 0.033 14.8 0.2 2.1 9.1 0.1 3.2 2 1 0 2 2 2 0 Aspartyl protease WD40 PF00400.32 KIK60513.1 - 2e-21 75.9 14.4 2e-06 28.4 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK60513.1 - 9e-09 35.5 0.1 0.27 11.6 0.0 4.4 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK60513.1 - 0.019 13.9 0.0 0.04 12.9 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CE2_N PF17996.1 KIK60514.1 - 0.0024 17.9 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Cecropin PF00272.19 KIK60514.1 - 0.22 11.3 0.3 0.35 10.6 0.3 1.3 1 0 0 1 1 1 0 Cecropin family Adeno_E3_CR2 PF02439.15 KIK60514.1 - 0.26 11.1 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rhomboid PF01694.22 KIK60517.1 - 1.5e-14 54.2 6.6 1.2e-09 38.4 2.9 2.1 2 0 0 2 2 2 2 Rhomboid family Rhomboid PF01694.22 KIK60519.1 - 4.3e-17 62.5 14.4 4.3e-16 59.2 14.4 2.3 1 1 0 1 1 1 1 Rhomboid family NFRKB_winged PF14465.6 KIK60519.1 - 0.0063 16.7 0.2 0.013 15.7 0.2 1.5 1 0 0 1 1 1 1 NFRKB Winged Helix-like zf-MYND PF01753.18 KIK60521.1 - 4.2e-11 42.8 13.6 6.6e-11 42.1 13.6 1.3 1 0 0 1 1 1 1 MYND finger ProRS-C_1 PF09180.11 KIK60521.1 - 0.0094 16.1 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal zf-C6H2 PF15801.5 KIK60521.1 - 0.026 14.8 7.6 0.05 13.9 7.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Methyltransf_16 PF10294.9 KIK60522.1 - 2.9e-21 76.0 0.0 4.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK60522.1 - 1.5e-07 31.4 0.0 3.3e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIK60522.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KIK60522.1 - 0.026 15.2 0.1 0.073 13.8 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK60522.1 - 0.029 15.1 0.0 0.076 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KIK60522.1 - 0.069 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Nnf1 PF03980.14 KIK60523.1 - 7.7e-15 55.2 1.9 1.2e-14 54.6 1.9 1.3 1 0 0 1 1 1 1 Nnf1 Prominin PF05478.11 KIK60523.1 - 0.0015 16.6 0.3 0.0017 16.4 0.3 1.0 1 0 0 1 1 1 1 Prominin Spc24 PF08286.11 KIK60523.1 - 0.0097 16.1 1.5 0.018 15.3 0.3 1.9 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Chalcone_2 PF16035.5 KIK60523.1 - 0.04 13.7 0.2 0.055 13.2 0.2 1.2 1 0 0 1 1 1 0 Chalcone isomerase like APG6_N PF17675.1 KIK60523.1 - 0.041 14.4 7.9 0.065 13.8 7.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KIK60523.1 - 0.23 11.2 5.2 0.098 12.4 1.5 2.0 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 KIK60523.1 - 0.35 11.3 6.3 0.11 13.0 2.5 2.0 2 0 0 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 KIK60523.1 - 2.3 8.6 5.9 3.2 8.1 0.8 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-RING_2 PF13639.6 KIK60524.1 - 2.7e-08 34.0 6.4 1.5e-07 31.6 3.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIK60524.1 - 5.1e-07 29.9 3.0 5.1e-07 29.9 3.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIK60524.1 - 1.7e-06 27.8 8.2 3.4e-06 26.8 3.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK60524.1 - 6.8e-05 22.5 4.1 0.0075 16.0 0.8 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 KIK60524.1 - 0.00034 20.5 1.4 0.00077 19.4 1.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK60524.1 - 0.00054 19.8 2.5 0.00054 19.8 2.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK60524.1 - 0.0006 19.6 1.8 0.0006 19.6 1.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK60524.1 - 0.00076 19.3 1.4 0.0016 18.2 1.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIK60524.1 - 0.0014 18.6 1.0 0.0042 17.1 1.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK60524.1 - 0.015 14.9 1.5 0.035 13.7 1.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KIK60524.1 - 0.11 12.4 1.1 0.29 11.0 1.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KIK60524.1 - 0.13 12.0 3.2 0.37 10.5 3.2 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.6 KIK60524.1 - 1.3 9.1 9.3 0.071 13.1 2.1 2.5 3 0 0 3 3 2 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KIK60524.1 - 2 8.5 5.9 0.6 10.2 2.6 1.9 2 0 0 2 2 1 0 Zinc-finger FANCL_C PF11793.8 KIK60524.1 - 3.3 8.0 4.8 12 6.2 3.2 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain DNA_pol_A_exo1 PF01612.20 KIK60525.1 - 1.2e-13 51.2 0.0 2.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Paf67 PF10255.9 KIK60525.1 - 0.018 14.0 0.3 0.03 13.3 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 PPC PF04151.15 KIK60527.1 - 0.71 11.0 4.5 0.77 10.9 2.0 2.4 1 1 1 2 2 2 0 Bacterial pre-peptidase C-terminal domain PCM1_C PF15717.5 KIK60528.1 - 0.008 14.9 0.8 0.0093 14.7 0.8 1.1 1 0 0 1 1 1 1 Pericentriolar material 1 C terminus Sec20 PF03908.13 KIK60531.1 - 0.075 13.0 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Sec20 Merozoite_SPAM PF07133.11 KIK60534.1 - 0.0031 17.5 2.3 0.0044 17.0 2.3 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) BH4 PF02180.17 KIK60535.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 CFEM PF05730.11 KIK60536.1 - 4.6e-16 58.7 15.6 5.5e-16 58.4 15.6 1.1 1 0 0 1 1 1 1 CFEM domain EHN PF06441.12 KIK60538.1 - 2.7e-33 114.6 0.1 2.2e-32 111.6 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK60538.1 - 1.8e-10 40.9 0.1 2.7e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK60538.1 - 5.2e-05 23.9 5.6 9.8e-05 23.1 5.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KIK60539.1 - 1.7e-33 115.2 0.1 1.2e-32 112.5 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK60539.1 - 8.7e-11 41.9 0.1 1.5e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK60539.1 - 0.00057 20.5 2.3 0.0016 19.1 2.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KIK60541.1 - 3.4e-28 98.2 0.0 4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Cas9-BH PF16593.5 KIK60543.1 - 0.047 13.4 1.0 0.047 13.4 1.0 2.2 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 Hydrophobin PF01185.18 KIK60545.1 - 2.8e-20 72.7 9.5 3.4e-20 72.5 9.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CLIP_SPH_mas PF18398.1 KIK60545.1 - 0.62 10.5 7.9 4.6 7.7 0.9 2.4 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade Hydrophobin PF01185.18 KIK60546.1 - 1.5e-19 70.4 7.6 4.4e-19 68.9 7.6 1.7 1 1 0 1 1 1 1 Fungal hydrophobin ECF-ribofla_trS PF07155.12 KIK60546.1 - 0.0095 15.9 0.3 0.016 15.2 0.3 1.4 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component Hydrophobin PF01185.18 KIK60547.1 - 2.1e-20 73.1 10.9 2.5e-20 72.9 10.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK60548.1 - 6.8e-13 49.1 0.8 7.4e-13 48.9 0.8 1.0 1 0 0 1 1 1 1 Fungal hydrophobin F_bP_aldolase PF01116.20 KIK60549.1 - 3.8e-91 305.5 0.0 4.2e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.11 KIK60549.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Torsin CPSase_L_D2 PF02786.17 KIK60549.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RRN3 PF05327.11 KIK60551.1 - 0.001 17.7 0.6 0.0012 17.4 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 MAGI_u5 PF16666.5 KIK60551.1 - 0.049 13.8 3.5 0.14 12.3 3.5 1.7 1 0 0 1 1 1 0 Unstructured region on MAGI FBPase_3 PF01950.16 KIK60551.1 - 0.11 11.6 0.0 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 Fructose-1,6-bisphosphatase ACP_syn_III_C PF08541.10 KIK60552.1 - 0.054 13.7 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal gag-asp_proteas PF13975.6 KIK60553.1 - 1.7e-07 31.7 0.0 2.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK60553.1 - 5.3e-06 27.0 0.0 9.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIK60553.1 - 0.0081 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DDE_3 PF13358.6 KIK60556.1 - 0.00024 20.9 0.1 0.00028 20.7 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AbiH PF14253.6 KIK60556.1 - 0.016 15.1 0.2 0.027 14.4 0.1 1.3 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF648 PF04890.13 KIK60559.1 - 0.075 12.8 0.5 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) zf-CCHC PF00098.23 KIK60560.1 - 8.1e-05 22.5 3.8 0.00015 21.7 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 KIK60560.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) FoP_duplication PF13865.6 KIK60560.1 - 1.5 9.4 5.0 0.66 10.6 0.6 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zf-C2HC5 PF06221.13 KIK60563.1 - 0.068 13.2 0.1 0.085 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FUSC-like PF12805.7 KIK60563.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Peptidase_S49_N PF08496.10 KIK60565.1 - 0.011 15.8 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LRS4 PF10422.9 KIK60565.1 - 0.021 14.4 8.3 0.034 13.7 8.3 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 HMMR_N PF15905.5 KIK60565.1 - 0.044 13.2 9.2 0.076 12.5 9.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 KIK60565.1 - 0.074 13.1 11.1 0.82 9.7 1.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.6 KIK60565.1 - 0.14 12.3 2.8 0.22 11.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_1 PF00170.21 KIK60565.1 - 0.14 12.3 6.9 4.5 7.4 2.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor YlbD_coat PF14071.6 KIK60565.1 - 0.15 12.4 2.2 0.37 11.1 2.2 1.6 1 0 0 1 1 1 0 Putative coat protein DUF1664 PF07889.12 KIK60565.1 - 0.15 12.1 2.7 0.27 11.3 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KIK60565.1 - 0.23 11.3 5.8 5.1 7.0 0.2 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3450 PF11932.8 KIK60565.1 - 0.27 10.5 13.0 0.079 12.2 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec2p PF06428.11 KIK60565.1 - 0.35 10.9 9.9 0.13 12.2 3.2 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 KIK60565.1 - 0.94 9.6 7.9 2.6 8.1 7.9 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KIK60565.1 - 1.2 9.3 7.2 4.8 7.4 7.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KIK60565.1 - 1.6 8.9 13.5 4.4 7.5 13.5 1.7 1 1 0 1 1 1 0 Tropomyosin like Csm1_N PF18504.1 KIK60565.1 - 1.6 9.1 11.0 8.4 6.8 0.8 2.5 1 1 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 KIK60565.1 - 3.9 7.9 8.8 12 6.4 8.7 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FAM76 PF16046.5 KIK60565.1 - 4.4 6.6 12.0 0.082 12.2 2.3 2.1 2 0 0 2 2 2 0 FAM76 protein Med9 PF07544.13 KIK60565.1 - 4.7 7.4 7.8 5.1 7.3 1.1 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BRE1 PF08647.11 KIK60565.1 - 9.3 6.4 11.6 2.7 8.1 3.3 2.2 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4768 PF15989.5 KIK60566.1 - 0.079 12.9 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4768) NuA4 PF09340.10 KIK60566.1 - 0.17 11.8 0.2 0.31 10.9 0.2 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF745 PF05335.13 KIK60566.1 - 0.25 11.0 3.0 5.8 6.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF648 PF04890.13 KIK60567.1 - 0.051 13.3 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF745 PF05335.13 KIK60567.1 - 0.42 10.3 2.6 10 5.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) HR1 PF02185.16 KIK60567.1 - 2 8.6 5.1 0.68 10.1 0.7 2.2 2 0 0 2 2 2 0 Hr1 repeat LRS4 PF10422.9 KIK60568.1 - 0.007 16.0 8.9 0.014 15.0 8.9 1.5 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Sec2p PF06428.11 KIK60568.1 - 0.013 15.5 1.5 0.013 15.5 1.5 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HMMR_N PF15905.5 KIK60568.1 - 0.02 14.4 10.5 0.035 13.6 10.5 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 KIK60568.1 - 0.029 13.7 2.5 0.048 13.0 2.5 1.3 1 0 0 1 1 1 0 FAM76 protein Peptidase_S49_N PF08496.10 KIK60568.1 - 0.031 14.4 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cnn_1N PF07989.11 KIK60568.1 - 0.04 14.1 0.3 0.04 14.1 0.3 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Bacillus_HBL PF05791.11 KIK60568.1 - 0.11 12.3 3.3 0.18 11.6 3.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 KIK60568.1 - 0.27 11.4 4.0 0.6 10.3 4.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KIK60568.1 - 0.61 10.7 4.0 1.8 9.3 3.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA DUF16 PF01519.16 KIK60568.1 - 1.1 9.7 4.1 2.4 8.7 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 KIK60568.1 - 4 7.5 12.9 8.5 6.5 0.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Integrase_H2C2 PF17921.1 KIK60573.1 - 1.3e-09 38.0 1.0 1.9e-09 37.5 1.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain PKD_channel PF08016.12 KIK60573.1 - 0.0045 15.7 0.9 0.0047 15.7 0.9 1.0 1 0 0 1 1 1 1 Polycystin cation channel FAM176 PF14851.6 KIK60574.1 - 0.017 14.7 1.7 0.023 14.4 1.7 1.2 1 0 0 1 1 1 0 FAM176 family Trypan_PARP PF05887.11 KIK60574.1 - 0.024 14.6 2.5 0.028 14.4 2.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 KIK60574.1 - 0.56 8.2 9.1 0.58 8.2 9.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM177 PF14774.6 KIK60574.1 - 0.72 10.2 5.6 0.9 9.9 5.6 1.2 1 0 0 1 1 1 0 FAM177 family Nucleo_P87 PF07267.11 KIK60574.1 - 0.94 8.3 6.3 1 8.1 6.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 KIK60574.1 - 1.8 6.7 11.2 2.1 6.4 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KIK60574.1 - 1.9 7.0 6.7 2.1 6.8 6.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 KIK60574.1 - 2.5 7.3 12.3 2.9 7.1 12.3 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KIK60574.1 - 10 4.3 8.7 11 4.2 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Occludin_ELL PF07303.13 KIK60575.1 - 0.63 10.8 5.2 1 10.1 2.7 2.6 2 1 0 2 2 2 0 Occludin homology domain RicinB_lectin_2 PF14200.6 KIK60576.1 - 2.7e-05 24.8 0.8 0.00096 19.8 0.7 2.1 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like AAA_16 PF13191.6 KIK60577.1 - 9.3e-08 32.6 0.0 3.6e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK60577.1 - 0.00029 20.8 0.8 0.081 12.8 0.2 2.4 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 KIK60577.1 - 0.0027 18.1 0.0 0.016 15.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KIK60577.1 - 0.0043 17.1 0.1 0.01 15.9 0.1 1.6 1 0 0 1 1 1 1 Torsin AAA_25 PF13481.6 KIK60577.1 - 0.0044 16.6 0.1 0.012 15.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KIK60577.1 - 0.017 14.3 0.1 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 KIK60577.1 - 0.086 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK60577.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK60577.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KIK60577.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KIK60577.1 - 0.16 11.1 0.0 0.45 9.7 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain Retrotran_gag_2 PF14223.6 KIK60578.1 - 4.2e-08 33.0 0.0 5.8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TAXi_C PF14541.6 KIK60579.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal ADIP PF11559.8 KIK60580.1 - 0.0015 18.6 5.1 0.0018 18.4 2.7 1.9 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 KIK60580.1 - 0.015 15.0 4.6 0.032 13.9 4.6 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4763 PF15960.5 KIK60580.1 - 0.026 13.8 2.5 0.045 13.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 KIK60580.1 - 0.03 13.2 3.1 0.048 12.5 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5471 PF17565.2 KIK60581.1 - 0.083 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5471) Val_tRNA-synt_C PF10458.9 KIK60581.1 - 0.12 12.7 0.3 9.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF745 PF05335.13 KIK60581.1 - 0.31 10.8 5.6 0.058 13.1 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sec2p PF06428.11 KIK60581.1 - 0.94 9.5 5.6 0.96 9.5 1.6 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Asp_protease_2 PF13650.6 KIK60582.1 - 0.00043 20.9 0.0 0.00071 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK60582.1 - 0.0032 18.0 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK60582.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease SASA PF03629.18 KIK60583.1 - 0.092 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase RicinB_lectin_2 PF14200.6 KIK60586.1 - 0.092 13.5 0.0 0.44 11.3 0.1 1.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 KIK60587.1 - 0.029 15.1 0.1 0.23 12.2 0.1 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ribosom_S30AE_C PF16321.5 KIK60587.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus DUF3612 PF12268.8 KIK60589.1 - 0.05 13.7 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3612) zf-CCHC PF00098.23 KIK60591.1 - 0.00012 22.0 3.8 0.00025 21.0 3.8 1.6 1 0 0 1 1 1 1 Zinc knuckle BAR_3 PF16746.5 KIK60592.1 - 0.00095 18.9 5.4 0.03 14.0 2.0 2.3 2 0 0 2 2 2 2 BAR domain of APPL family DUF648 PF04890.13 KIK60592.1 - 0.0088 15.8 0.3 0.013 15.3 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF648) Tox-ODYAM1 PF15642.6 KIK60592.1 - 0.073 12.0 0.7 0.1 11.6 0.7 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TSNAXIP1_N PF15739.5 KIK60592.1 - 0.079 13.3 3.9 0.2 12.0 3.8 1.6 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Amidinotransf PF02274.17 KIK60592.1 - 0.094 11.8 0.9 0.13 11.3 0.9 1.2 1 0 0 1 1 1 0 Amidinotransferase DUF745 PF05335.13 KIK60592.1 - 0.2 11.4 3.3 2.1 8.0 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK60592.1 - 0.4 10.6 3.7 5.5 6.9 0.3 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 KIK60592.1 - 2.1 7.7 11.2 0.062 12.8 5.2 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 SlyX PF04102.12 KIK60592.1 - 6.1 7.5 8.4 11 6.7 0.6 3.3 2 1 1 3 3 3 0 SlyX UPF0242 PF06785.11 KIK60592.1 - 6.5 6.8 9.2 0.5 10.4 4.6 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_S49_N PF08496.10 KIK60593.1 - 0.0077 16.3 0.6 0.013 15.5 0.6 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Fib_alpha PF08702.10 KIK60593.1 - 0.037 14.2 2.6 0.086 13.0 2.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 KIK60593.1 - 0.058 12.8 2.8 0.09 12.1 2.8 1.3 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 KIK60593.1 - 0.069 12.0 10.1 0.09 11.6 10.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KIK60593.1 - 0.092 12.6 0.8 0.25 11.2 0.7 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Csm1_N PF18504.1 KIK60593.1 - 0.095 13.1 8.6 0.86 10.0 1.8 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain ABC_tran_Xtn PF12848.7 KIK60593.1 - 0.1 12.7 2.0 0.19 11.8 2.0 1.4 1 0 0 1 1 1 0 ABC transporter Sec2p PF06428.11 KIK60593.1 - 0.22 11.5 7.5 0.15 12.1 3.1 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.8 KIK60593.1 - 0.6 10.1 12.5 0.46 10.5 3.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KIK60593.1 - 0.93 9.4 8.7 4.4 7.2 0.4 3.0 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 KIK60593.1 - 1 9.6 9.3 4.1 7.6 2.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KIK60593.1 - 2 8.5 9.1 5.5 7.0 2.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CC2-LZ PF16516.5 KIK60593.1 - 6.4 7.2 9.2 12 6.3 1.7 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LRS4 PF10422.9 KIK60593.1 - 9.6 5.7 12.2 1.7 8.1 8.3 1.7 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 RicinB_lectin_2 PF14200.6 KIK60594.1 - 4.9e-05 24.0 0.8 0.0019 18.9 0.6 2.1 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like gag-asp_proteas PF13975.6 KIK60597.1 - 1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK60597.1 - 1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIK60597.1 - 0.0099 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Cupin_4 PF08007.12 KIK60599.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 KIK60599.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase OTT_1508_deam PF14441.6 KIK60601.1 - 4.5e-09 36.2 0.1 1e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF1658 PF07871.11 KIK60602.1 - 0.62 10.1 3.8 24 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1658) 2OG-FeII_Oxy PF03171.20 KIK60603.1 - 0.15 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Plavaka PF18759.1 KIK60604.1 - 6.5e-15 55.2 0.1 8.4e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK60605.1 - 3.9e-62 210.4 0.0 4.6e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK60606.1 - 2.2e-14 53.4 0.4 4.2e-14 52.5 0.4 1.4 1 0 0 1 1 1 1 Plavaka transposase HAP2-GCS1 PF10699.9 KIK60609.1 - 0.055 13.5 0.1 0.22 11.5 0.1 2.1 1 0 0 1 1 1 0 Male gamete fusion factor Ribosomal_L2 PF00181.23 KIK60609.1 - 0.18 11.8 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain CxC2 PF18803.1 KIK60611.1 - 1.4e-14 54.1 1.2 9e-13 48.3 1.2 2.6 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases RicinB_lectin_2 PF14200.6 KIK60612.1 - 3.2e-07 31.0 1.1 6.5e-05 23.6 0.1 2.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 KIK60614.1 - 0.015 16.0 0.0 0.016 15.9 0.0 1.1 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like CAMSAP_CC1 PF17095.5 KIK60614.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Pox_Ag35 PF03286.14 KIK60618.1 - 0.38 10.5 8.2 0.6 9.9 8.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 KIK60618.1 - 0.87 7.8 5.9 0.99 7.6 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KIK60618.1 - 2.2 7.5 10.5 3.5 6.9 10.5 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KIK60618.1 - 2.3 6.2 9.7 3.3 5.7 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen S-antigen PF05756.11 KIK60619.1 - 0.0095 16.3 0.3 0.023 15.1 0.3 1.6 1 0 0 1 1 1 1 S-antigen protein TFIIF_alpha PF05793.12 KIK60619.1 - 2.2 6.8 6.8 2.4 6.7 6.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.16 KIK60621.1 - 0.012 14.9 3.6 0.02 14.1 3.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.18 KIK60621.1 - 0.063 13.2 2.4 0.097 12.6 2.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 KIK60621.1 - 0.098 10.9 7.6 0.16 10.1 7.6 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KIK60621.1 - 0.19 9.8 14.9 0.33 9.0 13.5 1.8 2 0 0 2 2 2 0 DNA polymerase phi Med17 PF10156.9 KIK60621.1 - 0.87 8.2 5.9 1.2 7.7 5.9 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RPA43_OB PF17875.1 KIK60621.1 - 0.92 10.1 8.7 0.11 13.1 3.7 1.9 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Astro_capsid_p PF12226.8 KIK60621.1 - 2.3 7.3 7.1 3.6 6.7 7.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein WRNPLPNID PF15017.6 KIK60621.1 - 5.5 7.9 19.9 2.9 8.8 13.9 2.9 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box CDC45 PF02724.14 KIK60621.1 - 9.7 4.3 9.3 16 3.7 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein KDZ PF18758.1 KIK60623.1 - 7.9e-08 32.2 0.2 1.1e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK60624.1 - 7.7e-29 100.9 2.0 8.7e-29 100.7 2.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MaoC_dehydrat_N PF13452.6 KIK60626.1 - 1.5e-06 28.4 0.0 4.1e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAM75 PF14650.6 KIK60631.1 - 3.7 7.0 10.8 4.3 6.8 10.8 1.3 1 0 0 1 1 1 0 FAM75 family Alpha_kinase PF02816.18 KIK60634.1 - 1.9e-12 47.7 0.4 2.1e-12 47.5 0.4 1.0 1 0 0 1 1 1 1 Alpha-kinase family Plavaka PF18759.1 KIK60638.1 - 5.2e-05 22.6 0.1 6.9e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Elongin_A PF06881.11 KIK60640.1 - 0.095 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4718 PF15842.5 KIK60641.1 - 0.83 9.4 4.6 2.6 7.8 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4718) Gemini_AC4_5 PF04807.12 KIK60642.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Nop14 PF04147.12 KIK60642.1 - 6.8 4.8 34.5 9.3 4.3 34.5 1.2 1 0 0 1 1 1 0 Nop14-like family NPL PF17800.1 KIK60644.1 - 3.3e-07 30.8 0.0 4.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain DUF1068 PF06364.12 KIK60647.1 - 0.018 14.9 0.5 0.031 14.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) WD40 PF00400.32 KIK60648.1 - 0.039 14.8 3.3 0.49 11.4 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK60648.1 - 0.14 11.8 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain RunxI PF08504.11 KIK60649.1 - 0.062 14.0 2.8 3.1 8.5 1.0 2.1 2 0 0 2 2 2 0 Runx inhibition domain AAA_lid_3 PF17862.1 KIK60651.1 - 0.062 13.1 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA+ lid domain Peptidase_C48 PF02902.19 KIK60653.1 - 7.6e-13 48.8 0.0 8.2e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C39 PF03412.15 KIK60653.1 - 0.08 12.8 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase C39 family Hex_IIIa PF02455.16 KIK60653.1 - 0.13 11.0 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SYCE1 PF15233.6 KIK60655.1 - 0.0069 16.5 3.7 0.012 15.6 3.7 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 CdvA PF18822.1 KIK60655.1 - 0.0073 16.1 1.9 0.012 15.4 1.9 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain TSNAXIP1_N PF15739.5 KIK60655.1 - 0.037 14.4 2.3 0.037 14.4 2.3 1.5 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus HALZ PF02183.18 KIK60655.1 - 1.4 9.2 7.8 0.22 11.7 1.2 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Utp21 PF04192.12 KIK60656.1 - 0.002 17.7 0.1 0.0035 16.9 0.1 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Ubiquitin_2 PF14560.6 KIK60659.1 - 0.16 12.4 0.9 13 6.3 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain LMBR1 PF04791.16 KIK60661.1 - 0.027 13.4 3.8 0.033 13.1 3.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein KASH_CCD PF14662.6 KIK60663.1 - 0.0037 17.1 3.9 0.0057 16.5 3.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KIK60663.1 - 0.015 14.2 2.3 0.021 13.7 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_S49_N PF08496.10 KIK60663.1 - 0.023 14.8 0.1 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec2p PF06428.11 KIK60663.1 - 0.029 14.3 2.1 0.059 13.3 0.4 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p PKcGMP_CC PF16808.5 KIK60663.1 - 0.042 13.7 3.9 4.9 7.1 0.2 2.8 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 KIK60663.1 - 0.075 12.5 2.1 0.11 12.0 2.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spore_III_AB PF09548.10 KIK60663.1 - 0.09 12.9 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LRS4 PF10422.9 KIK60663.1 - 0.096 12.2 2.0 0.15 11.6 2.0 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Phage_GP20 PF06810.11 KIK60663.1 - 0.13 12.1 2.1 8.1 6.2 0.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Med9 PF07544.13 KIK60663.1 - 0.77 9.9 2.3 6.2 7.0 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Csm1_N PF18504.1 KIK60663.1 - 0.87 10.0 4.5 8.5 6.8 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FAM76 PF16046.5 KIK60663.1 - 4.5 6.5 8.9 0.37 10.1 0.2 2.2 2 0 0 2 2 2 0 FAM76 protein DUF648 PF04890.13 KIK60664.1 - 0.17 11.6 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Retrotrans_gag PF03732.17 KIK60665.1 - 3.5e-09 36.8 0.1 1e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein F-box-like PF12937.7 KIK60666.1 - 4.8e-05 23.2 2.1 0.00011 22.0 2.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK60666.1 - 0.04 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 F-box domain WD40 PF00400.32 KIK60668.1 - 0.009 16.8 0.1 0.099 13.6 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK60668.1 - 0.12 11.9 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain Tox-REase-2 PF15646.6 KIK60669.1 - 0.12 12.6 0.2 0.32 11.2 0.1 1.7 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 SR-25 PF10500.9 KIK60670.1 - 0.031 13.9 2.2 0.044 13.4 2.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_C48 PF02902.19 KIK60671.1 - 5.9e-28 98.2 0.2 1e-27 97.4 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4218 PF13960.6 KIK60673.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) NPL PF17800.1 KIK60677.1 - 0.00048 20.7 0.0 0.0014 19.2 0.0 1.7 2 0 0 2 2 2 1 Nucleoplasmin-like domain DUF5481 PF17578.2 KIK60678.1 - 0.11 12.9 0.8 0.14 12.6 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5481) Phage_30_3 PF08010.11 KIK60680.1 - 0.055 13.3 1.0 0.085 12.7 0.6 1.6 1 1 1 2 2 2 0 Bacteriophage protein GP30.3 YabA PF06156.13 KIK60680.1 - 0.064 13.9 9.5 1.5 9.5 1.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF1002 PF06207.11 KIK60680.1 - 0.065 12.8 3.1 0.081 12.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) RIG-I_C PF18119.1 KIK60680.1 - 0.13 12.3 5.0 0.19 11.7 1.3 2.1 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain Fmp27_WPPW PF10359.9 KIK60680.1 - 0.18 10.6 5.7 0.21 10.4 5.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Lectin_N PF03954.14 KIK60680.1 - 0.52 10.1 3.9 0.47 10.2 1.4 1.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain ADIP PF11559.8 KIK60680.1 - 0.76 9.8 14.8 1.4 9.0 3.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fungal_TACC PF12709.7 KIK60680.1 - 0.86 10.1 8.8 1.9 9.0 1.5 2.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins VIT1 PF01988.19 KIK60680.1 - 0.91 9.4 2.4 1.2 9.0 2.4 1.2 1 0 0 1 1 1 0 VIT family DUF4407 PF14362.6 KIK60680.1 - 2.2 7.6 7.7 2.9 7.2 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alpha_kinase PF02816.18 KIK60683.1 - 2.5e-09 37.5 0.1 6.3e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 Alpha-kinase family DUF3029 PF11230.8 KIK60684.1 - 0.16 10.3 0.0 0.45 8.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3029) Pea-VEAacid PF08111.11 KIK60684.1 - 0.26 11.7 1.2 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Pea-VEAacid family PIF1 PF05970.14 KIK60685.1 - 3.8e-11 42.8 0.2 5.1e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK60685.1 - 2.4e-07 30.7 0.2 3.2e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK60685.1 - 3.4e-05 23.4 0.2 4.3e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KIK60685.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK60685.1 - 0.00017 22.0 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK60685.1 - 0.0002 21.7 0.5 0.00059 20.2 0.1 1.7 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 KIK60685.1 - 0.00095 19.7 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 KIK60685.1 - 0.0023 18.3 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 KIK60685.1 - 0.0037 16.7 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIK60685.1 - 0.006 16.9 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK60685.1 - 0.0061 16.5 0.1 0.0068 16.3 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KIK60685.1 - 0.015 14.3 0.1 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KIK60685.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 KIK60685.1 - 0.019 14.5 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KIK60685.1 - 0.023 14.7 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KIK60685.1 - 0.027 14.9 0.3 0.048 14.1 0.1 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK60685.1 - 0.028 14.3 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 KIK60685.1 - 0.032 14.2 0.0 0.04 13.8 0.0 1.3 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 KIK60685.1 - 0.038 13.8 0.2 0.062 13.1 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK60685.1 - 0.055 13.2 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_35 PF14516.6 KIK60685.1 - 0.062 12.1 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ATPase_2 PF01637.18 KIK60685.1 - 0.076 12.9 0.1 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 KIK60685.1 - 0.084 11.7 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_33 PF13671.6 KIK60685.1 - 0.11 12.6 0.1 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpb1_5 PF04998.17 KIK60686.1 - 6e-87 291.5 0.1 7.9e-87 291.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 KIK60686.1 - 6.1e-36 123.7 0.0 2.7e-35 121.6 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KIK60686.1 - 2.9e-32 111.5 0.6 5.9e-32 110.5 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_6 PF04992.14 KIK60686.1 - 2.1e-26 93.0 0.5 8.9e-15 55.0 0.2 2.7 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.17 KIK60686.1 - 1.1e-22 80.0 0.2 7.7e-22 77.3 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_2 PF00623.20 KIK60686.1 - 4.4e-15 56.3 0.0 1.2e-08 35.4 0.0 3.3 1 1 2 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KIK60686.1 - 2.2e-13 50.3 0.0 4.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_R PF05001.13 KIK60686.1 - 0.11 12.9 52.2 0.028 14.8 8.0 5.5 4 1 1 5 5 5 0 RNA polymerase Rpb1 C-terminal repeat E1_FCCH PF16190.5 KIK60691.1 - 0.086 13.0 1.8 4.3 7.6 1.8 2.3 1 1 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain BOFC_N PF08977.10 KIK60697.1 - 0.16 12.0 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal DUF963 PF06131.11 KIK60701.1 - 0.0042 16.5 4.9 0.0042 16.5 4.9 2.9 2 1 0 2 2 2 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) IMP2_C PF18591.1 KIK60706.1 - 0.15 11.9 0.3 15 5.6 0.1 2.2 1 1 1 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Strabismus PF06638.11 KIK60709.1 - 0.038 12.7 2.6 0.056 12.1 2.6 1.2 1 0 0 1 1 1 0 Strabismus protein Creatinase_N_2 PF16189.5 KIK60710.1 - 1.2e-42 145.8 0.0 6.4e-42 143.4 0.0 2.2 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KIK60710.1 - 1.1e-39 136.3 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KIK60710.1 - 2.3e-25 88.4 0.6 3e-23 81.7 0.2 2.6 2 0 0 2 2 2 2 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIK60710.1 - 1.6e-14 54.7 0.0 1.6e-13 51.5 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Polysacc_deac_1 PF01522.21 KIK60711.1 - 5.6e-28 97.3 0.0 8.6e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIK60711.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 AAA_11 PF13086.6 KIK60713.1 - 2e-25 90.1 0.0 7.9e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK60713.1 - 9.3e-12 45.1 0.0 5.5e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.8 KIK60713.1 - 8.5e-10 38.7 2.3 0.0014 18.9 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding AAA_19 PF13245.6 KIK60713.1 - 1.4e-09 38.4 0.0 2e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain zf-met PF12874.7 KIK60713.1 - 8.3e-06 26.0 5.3 0.012 16.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type UvrD-helicase PF00580.21 KIK60713.1 - 1.1e-05 25.1 0.0 0.006 16.1 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain zf-C2H2_2 PF12756.7 KIK60713.1 - 6.2e-05 23.3 3.0 0.18 12.1 0.0 3.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) PhoH PF02562.16 KIK60713.1 - 0.00012 21.7 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KIK60713.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK60713.1 - 0.025 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.6 KIK60713.1 - 0.057 14.3 2.0 18 6.5 0.1 3.3 3 0 0 3 3 2 0 C2H2-type zinc finger DUF2075 PF09848.9 KIK60713.1 - 0.075 12.3 0.0 0.87 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KIK60713.1 - 0.083 12.6 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KIK60713.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 KIK60713.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase PIF1 PF05970.14 KIK60713.1 - 0.12 11.6 0.0 5 6.2 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_7 PF12775.7 KIK60713.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_12 PF13087.6 KIK60714.1 - 1.1e-30 106.8 0.0 1.3e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain DUF3873 PF12989.7 KIK60714.1 - 0.06 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Mt_ATP_synt PF15704.5 KIK60714.1 - 0.15 11.9 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit AAA_12 PF13087.6 KIK60715.1 - 6.2e-47 159.8 0.0 1.3e-46 158.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK60715.1 - 7.8e-26 91.4 0.0 8.6e-12 45.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain zf-C2H2_jaz PF12171.8 KIK60715.1 - 3.5e-12 46.3 9.9 1.8e-05 24.9 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding AAA_30 PF13604.6 KIK60715.1 - 1.5e-10 41.1 0.0 4.9e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK60715.1 - 7.6e-09 36.1 0.0 7.6e-08 32.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain zf-met PF12874.7 KIK60715.1 - 2e-07 31.2 15.8 0.00059 20.1 1.2 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type UvrD-helicase PF00580.21 KIK60715.1 - 3.4e-06 26.8 0.0 0.0085 15.7 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KIK60715.1 - 9.2e-05 22.0 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein zf-C2H2_2 PF12756.7 KIK60715.1 - 0.00011 22.5 5.9 0.044 14.1 0.2 3.3 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) Viral_helicase1 PF01443.18 KIK60715.1 - 0.0015 18.3 0.0 8.8 6.0 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase zf-C2H2_4 PF13894.6 KIK60715.1 - 0.0075 17.0 5.0 0.19 12.7 0.2 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger ResIII PF04851.15 KIK60715.1 - 0.0081 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KIK60715.1 - 0.013 15.4 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Helicase UvrD_C_2 PF13538.6 KIK60715.1 - 0.02 14.7 0.3 0.15 11.9 0.3 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain zf-C2H2 PF00096.26 KIK60715.1 - 0.021 15.3 0.4 0.021 15.3 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA_22 PF13401.6 KIK60715.1 - 0.027 14.7 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK60715.1 - 0.054 13.9 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KIK60715.1 - 0.067 12.4 0.0 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATPase_2 PF01637.18 KIK60715.1 - 0.09 12.7 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KIK60715.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1917 PF08939.10 KIK60718.1 - 6.1e-22 78.8 1.1 3.8e-19 69.6 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1917) YqgF PF14639.6 KIK60718.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 MFS_1 PF07690.16 KIK60719.1 - 2.1e-23 82.8 44.6 7.2e-23 81.1 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ChAPs PF09295.10 KIK60721.1 - 1.4e-142 475.4 0.0 3.9e-141 470.6 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KIK60721.1 - 0.00012 22.5 0.0 0.082 13.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60721.1 - 0.0046 17.0 2.7 2.9 8.2 0.1 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIK60721.1 - 0.006 15.8 0.3 0.78 8.9 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.8 KIK60721.1 - 0.015 14.2 0.0 0.27 10.1 0.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 KIK60721.1 - 0.054 13.7 0.0 1 9.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BAR_2 PF10455.9 KIK60721.1 - 0.06 12.5 0.3 0.9 8.6 0.1 2.1 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Golgin_A5 PF09787.9 KIK60723.1 - 0.00051 19.6 6.6 0.00051 19.6 6.6 1.6 1 1 1 2 2 2 1 Golgin subfamily A member 5 DUF2046 PF09755.9 KIK60723.1 - 0.0012 18.2 0.4 0.0012 18.2 0.4 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) NRBF2 PF08961.10 KIK60723.1 - 0.0026 17.4 2.9 0.0026 17.4 2.9 2.9 2 1 1 3 3 3 1 Nuclear receptor-binding factor 2, autophagy regulator Rootletin PF15035.6 KIK60723.1 - 0.0081 16.2 14.8 0.013 15.5 13.3 1.9 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion Jnk-SapK_ap_N PF09744.9 KIK60723.1 - 0.0096 16.2 6.6 0.0096 16.2 6.6 2.0 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 MapZ_EC1 PF18041.1 KIK60723.1 - 0.027 14.7 0.4 0.058 13.6 0.0 1.6 2 0 0 2 2 2 0 MapZ extracellular domain 1 HALZ PF02183.18 KIK60723.1 - 0.063 13.5 1.5 0.063 13.5 1.5 4.1 2 1 2 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KIK60723.1 - 0.11 12.6 0.6 0.11 12.6 0.6 2.8 2 1 2 4 4 4 0 bZIP transcription factor Spc7 PF08317.11 KIK60723.1 - 0.17 10.7 10.4 0.018 13.9 3.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.6 KIK60723.1 - 0.27 10.8 8.0 0.41 10.2 8.0 1.4 1 1 0 1 1 1 0 TMCO5 family OmpH PF03938.14 KIK60723.1 - 0.71 10.2 4.9 0.24 11.7 0.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PRKG1_interact PF15898.5 KIK60723.1 - 1.3 10.0 15.8 1.7 9.6 9.7 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DASH_Hsk3 PF08227.11 KIK60723.1 - 1.8 9.0 6.4 48 4.4 0.1 3.5 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like YabA PF06156.13 KIK60723.1 - 6.5 7.4 11.7 13 6.5 8.2 2.8 2 1 0 2 2 2 0 Initiation control protein YabA DUF2046 PF09755.9 KIK60724.1 - 0.014 14.7 4.7 0.026 13.8 4.7 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Cnn_1N PF07989.11 KIK60724.1 - 0.1 12.8 0.3 0.1 12.8 0.3 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KIK60724.1 - 1.8 9.2 4.1 1.4 9.6 1.3 2.0 1 1 0 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 KIK60724.1 - 2 8.9 5.8 0.45 10.9 0.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 KIK60724.1 - 3 8.0 12.7 0.51 10.5 2.2 3.2 3 0 0 3 3 3 0 Basic region leucine zipper ATG16 PF08614.11 KIK60724.1 - 3.1 8.0 11.7 0.65 10.2 1.4 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) p450 PF00067.22 KIK60729.1 - 3.7e-36 124.9 0.0 5.1e-35 121.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2046 PF09755.9 KIK60730.1 - 1.4e-12 47.5 14.1 4.5e-12 45.8 11.7 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Myc-LZ PF02344.15 KIK60730.1 - 0.027 14.5 2.7 0.22 11.6 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain Wtap PF17098.5 KIK60730.1 - 0.15 12.0 6.9 0.35 10.8 6.9 1.6 1 1 0 1 1 1 0 WTAP/Mum2p family FlaC_arch PF05377.11 KIK60730.1 - 0.5 10.8 0.1 0.5 10.8 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KIK60730.1 - 1 8.6 5.8 1.5 8.1 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKG6 PF08693.10 KIK60731.1 - 0.021 14.2 0.5 0.065 12.7 0.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 KIK60731.1 - 0.037 13.7 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2207 PF09972.9 KIK60731.1 - 0.22 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MGC-24 PF05283.11 KIK60731.1 - 5.2 7.5 18.5 0.38 11.2 10.2 3.0 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AA_kinase PF00696.28 KIK60732.1 - 3.7e-38 131.5 0.0 1.3e-37 129.7 0.0 1.9 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KIK60732.1 - 1.9e-08 34.0 2.0 5.4e-05 22.9 0.1 3.2 4 0 0 4 4 4 2 ACT domain ACT PF01842.25 KIK60732.1 - 3.3e-07 30.0 0.6 0.04 13.7 0.0 2.8 2 0 0 2 2 2 2 ACT domain dsrm PF00035.26 KIK60732.1 - 0.068 13.9 0.3 0.17 12.6 0.3 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif p450 PF00067.22 KIK60733.1 - 1.3e-54 185.7 0.0 1.8e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ACT_7 PF13840.6 KIK60734.1 - 2e-07 30.7 0.1 2.3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 KIK60734.1 - 3.4e-05 23.5 0.1 4.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 ACT domain p450 PF00067.22 KIK60735.1 - 7.7e-55 186.5 0.0 1e-54 186.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK60736.1 - 2.4e-56 191.4 0.0 3.2e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KDZ PF18758.1 KIK60737.1 - 6.4e-41 140.4 7.4 9.1e-23 81.0 0.1 3.1 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK60737.1 - 5.6e-34 116.5 0.7 1.5e-33 115.2 0.7 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK60737.1 - 1.4e-05 25.2 0.4 3.8e-05 23.8 0.4 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Myb_DNA-bind_6 PF13921.6 KIK60739.1 - 2.2e-15 56.6 4.8 3.6e-13 49.6 0.8 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK60739.1 - 2e-14 53.5 9.1 4e-09 36.5 0.5 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KIK60739.1 - 0.032 14.4 0.6 0.049 13.8 0.2 1.6 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Ank PF00023.30 KIK60741.1 - 1.7e-15 56.7 6.3 0.0062 16.9 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KIK60741.1 - 7.5e-14 52.1 1.8 2e-09 37.9 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK60741.1 - 1e-13 51.5 0.1 0.00041 20.9 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK60741.1 - 7.9e-11 41.2 0.1 1.1 10.0 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KIK60741.1 - 0.0072 16.6 0.1 0.87 10.0 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) YajC PF02699.15 KIK60741.1 - 0.06 13.2 3.7 23 5.0 0.1 3.7 1 1 2 4 4 4 0 Preprotein translocase subunit Arg_repressor PF01316.21 KIK60741.1 - 0.075 12.8 3.1 5.9 6.7 0.1 3.8 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain HTH_22 PF13309.6 KIK60741.1 - 0.13 12.4 0.0 5 7.3 0.0 3.1 3 0 0 3 3 3 0 HTH domain ParBc PF02195.18 KIK60742.1 - 0.065 13.5 0.3 0.1 12.9 0.3 1.3 1 0 0 1 1 1 0 ParB-like nuclease domain CD45 PF12567.8 KIK60747.1 - 0.049 13.6 0.4 0.081 12.9 0.4 1.3 1 0 0 1 1 1 0 Leukocyte receptor CD45 NACHT PF05729.12 KIK60750.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATP-synt_ab PF00006.25 KIK60750.1 - 0.0054 16.4 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 KIK60750.1 - 0.0096 16.4 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 KIK60750.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK60750.1 - 0.014 15.7 0.0 0.031 14.7 0.0 1.6 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.15 KIK60750.1 - 0.017 15.1 0.4 0.044 13.8 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK60750.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK60750.1 - 0.025 14.9 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KIK60750.1 - 0.045 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIK60750.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK60750.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PATR PF12951.7 KIK60750.1 - 0.78 9.9 3.7 1.2 9.3 0.7 2.4 2 0 0 2 2 2 0 Passenger-associated-transport-repeat Ank_4 PF13637.6 KIK60751.1 - 8.1e-25 86.9 0.4 2.8e-07 31.0 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK60751.1 - 5.2e-17 62.2 2.2 4e-09 36.9 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60751.1 - 1.3e-15 57.1 2.5 0.00044 20.6 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KIK60751.1 - 6.6e-12 44.5 0.4 0.038 14.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KIK60751.1 - 0.00044 20.5 0.3 4.3 7.8 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF3710 PF12502.8 KIK60751.1 - 0.071 12.8 0.9 8.5 6.0 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3710) DUF1985 PF09331.11 KIK60754.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) RVT_1 PF00078.27 KIK60756.1 - 1.4e-06 28.0 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NACHT PF05729.12 KIK60759.1 - 7.8e-08 32.4 0.8 1.8e-07 31.2 0.7 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK60759.1 - 1.4e-05 25.5 0.3 3.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK60759.1 - 2.3e-05 24.7 0.1 8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIK60759.1 - 4.6e-05 23.5 1.6 0.0043 17.1 0.4 3.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KIK60759.1 - 0.0023 18.4 0.1 0.0066 17.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KIK60759.1 - 0.021 14.0 1.0 0.05 12.8 1.0 1.7 1 1 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KIK60759.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KIK60759.1 - 0.051 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF2075 PF09848.9 KIK60759.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SPATIAL PF15256.6 KIK60759.1 - 0.12 12.7 0.4 0.28 11.5 0.2 1.7 2 0 0 2 2 2 0 SPATIAL KAP_NTPase PF07693.14 KIK60759.1 - 0.94 8.7 4.8 6.3 5.9 0.4 2.6 2 1 1 3 3 3 0 KAP family P-loop domain Ank_2 PF12796.7 KIK60760.1 - 2.6e-18 66.4 1.3 2e-13 50.7 0.6 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK60760.1 - 7.8e-14 51.9 0.0 5.6e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK60760.1 - 3.3e-13 48.5 0.0 0.00078 19.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KIK60760.1 - 7.5e-13 48.3 0.0 0.00018 21.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KIK60760.1 - 1e-06 28.9 0.0 0.0035 17.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1966 PF09260.11 KIK60760.1 - 0.0073 16.6 0.1 0.35 11.2 0.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1966) Ank_2 PF12796.7 KIK60763.1 - 4.8e-13 49.5 3.9 5.9e-10 39.6 0.8 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60763.1 - 2.9e-12 46.4 0.7 0.00074 19.9 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KIK60763.1 - 3.6e-10 40.2 0.1 0.00046 20.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK60763.1 - 2.1e-09 36.8 0.2 0.0084 16.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KIK60763.1 - 0.00029 21.1 0.3 5.4 7.5 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF3710 PF12502.8 KIK60763.1 - 0.12 12.1 0.7 55 3.4 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3710) DUF643 PF04867.12 KIK60764.1 - 0.079 13.6 0.0 0.36 11.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF643) Utp12 PF04003.12 KIK60764.1 - 0.12 12.7 0.8 0.3 11.4 0.7 1.7 1 1 0 1 1 1 0 Dip2/Utp12 Family CorA PF01544.18 KIK60764.1 - 0.19 11.0 4.8 0.22 10.8 3.9 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein BAR_3 PF16746.5 KIK60764.1 - 1.2 8.8 9.6 0.62 9.7 2.3 2.1 2 0 0 2 2 2 0 BAR domain of APPL family TFIIA PF03153.13 KIK60764.1 - 9.8 6.1 30.3 0.016 15.2 16.3 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit FCH PF00611.23 KIK60765.1 - 8.7e-15 54.8 0.4 8.7e-15 54.8 0.4 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIK60765.1 - 8e-10 38.2 0.1 1.5e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK60765.1 - 5.3e-09 35.8 0.1 9.7e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK60765.1 - 1.9e-05 24.3 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain NABP PF07990.12 KIK60765.1 - 0.00011 21.9 1.9 0.0002 21.1 1.9 1.4 1 0 0 1 1 1 1 Nucleic acid binding protein NABP Uteroglobin PF01099.17 KIK60765.1 - 4.1 7.8 5.3 8.2 6.8 0.1 2.9 3 0 0 3 3 3 0 Uteroglobin family Glyco_hydro_16 PF00722.21 KIK60766.1 - 5e-19 68.4 1.4 5e-19 68.4 1.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ank_2 PF12796.7 KIK60767.1 - 2.6e-15 56.8 0.2 2.9e-09 37.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK60767.1 - 2.9e-07 30.7 0.1 0.016 15.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK60767.1 - 1.9e-06 27.7 0.1 0.081 13.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIK60767.1 - 1.3e-05 25.4 1.1 0.01 16.3 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KIK60767.1 - 6.7e-05 23.4 0.1 0.00015 22.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF1772 PF08592.11 KIK60768.1 - 0.34 11.2 3.5 3.6 7.9 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) p450 PF00067.22 KIK60769.1 - 1.8e-73 247.9 0.0 6.4e-73 246.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Uso1_p115_head PF04869.14 KIK60771.1 - 1e-45 156.3 0.0 8.3e-37 127.0 0.0 2.9 3 0 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KIK60771.1 - 2.8e-16 60.0 19.3 6.3e-16 58.9 19.3 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 KIK60771.1 - 0.0035 17.4 8.5 0.19 11.8 2.2 2.5 2 0 0 2 2 2 2 TolA binding protein trimerisation Spc7 PF08317.11 KIK60771.1 - 0.012 14.5 6.0 0.018 13.9 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3818 PF12825.7 KIK60771.1 - 0.022 13.8 1.7 0.036 13.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) ABC_tran_CTD PF16326.5 KIK60771.1 - 0.035 14.3 4.2 16 5.8 0.0 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 KIK60771.1 - 0.091 12.1 2.1 0.15 11.3 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 KIK60771.1 - 0.11 12.8 11.2 1.3 9.4 3.5 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Bap31_Bap29_C PF18035.1 KIK60771.1 - 0.11 12.5 6.6 0.57 10.2 6.5 2.4 2 0 0 2 2 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2570 PF10828.8 KIK60771.1 - 0.21 11.4 5.2 0.6 10.0 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SBF2 PF12335.8 KIK60771.1 - 0.26 10.9 1.5 0.52 9.9 1.5 1.4 1 0 0 1 1 1 0 Myotubularin protein ADIP PF11559.8 KIK60771.1 - 0.33 11.0 6.5 0.73 9.9 6.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MAGI_u1 PF16663.5 KIK60771.1 - 1.1 9.4 3.7 3.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Unstructured region on MAGI DUF4140 PF13600.6 KIK60771.1 - 1.5 9.3 5.3 3.8 8.0 5.3 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KIK60771.1 - 2.2 8.8 13.2 4.3 7.9 13.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KIK60771.1 - 8.9 7.0 9.8 5.8 7.6 1.2 2.8 2 0 0 2 2 2 0 SlyX Glyco_hydr_30_2 PF14587.6 KIK60772.1 - 4e-23 82.6 0.0 7.8e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Orthopox_F14 PF06076.12 KIK60776.1 - 0.025 14.8 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus F14 protein EF_TS PF00889.19 KIK60778.1 - 0.06 12.9 1.0 0.46 10.1 0.0 2.1 1 1 1 2 2 2 0 Elongation factor TS MukF_C PF17193.4 KIK60781.1 - 0.0049 17.0 0.1 0.009 16.2 0.1 1.4 1 0 0 1 1 1 1 MukF C-terminal domain Glyco_hydro_43 PF04616.14 KIK60783.1 - 9.5e-20 71.1 12.9 4.7e-11 42.5 0.1 3.1 3 0 0 3 3 3 2 Glycosyl hydrolases family 43 DUF4981 PF16353.5 KIK60783.1 - 0.011 16.2 0.1 0.023 15.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) Amidase PF01425.21 KIK60784.1 - 1.6e-82 277.9 0.0 2e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Cwf_Cwc_15 PF04889.12 KIK60785.1 - 2.7e-82 276.2 29.5 3e-82 276.1 29.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KIK60785.1 - 0.04 12.1 29.9 0.049 11.9 29.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIK60785.1 - 0.046 13.2 32.4 0.058 12.8 32.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIK60785.1 - 1.7 7.9 30.0 2.1 7.6 30.0 1.1 1 0 0 1 1 1 0 BUD22 MFAP1 PF06991.11 KIK60785.1 - 6.4 6.6 38.2 19 5.0 38.2 1.7 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DNA_pol_phi PF04931.13 KIK60785.1 - 6.9 4.6 38.2 9.4 4.2 38.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 KIK60785.1 - 7.6 5.2 13.0 9 4.9 13.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Aldo_ket_red PF00248.21 KIK60786.1 - 5e-48 163.8 0.2 3.8e-47 160.9 0.2 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-bind_6 PF13921.6 KIK60787.1 - 7.7e-37 125.4 4.2 1.2e-15 57.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK60787.1 - 4.6e-36 122.8 6.2 1.8e-11 44.0 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK60787.1 - 0.0019 18.6 5.3 3.4 8.1 0.8 4.0 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIK60787.1 - 0.047 13.6 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KIK60787.1 - 0.11 12.7 0.0 25 5.1 0.0 3.2 3 0 0 3 3 3 0 Rap1 Myb domain Bac_A_amyl_C PF18612.1 KIK60791.1 - 0.0063 16.3 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Bacterial Alpha amylase C-terminal domain Gln-synt_C PF00120.24 KIK60795.1 - 9e-73 245.2 0.0 1.2e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KIK60795.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain DUF2235 PF09994.9 KIK60796.1 - 1.1e-94 317.0 0.0 1.5e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK60797.1 - 1.1e-94 317.0 0.0 1.5e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK60798.1 - 2.7e-94 315.8 0.1 4.1e-94 315.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 KIK60799.1 - 1e-28 100.6 1.1 5.4e-20 71.9 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Neur_chan_memb PF02932.16 KIK60799.1 - 0.085 12.9 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAD_binding_4 PF01565.23 KIK60801.1 - 2e-10 40.5 0.0 0.00041 20.1 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 KIK60801.1 - 6.2e-09 35.8 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KIK60801.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.14 KIK60801.1 - 0.028 14.2 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase SPX PF03105.19 KIK60801.1 - 7 6.5 14.4 9.8 6.0 14.4 1.2 1 0 0 1 1 1 0 SPX domain RhoGEF PF00621.20 KIK60802.1 - 1.2e-31 110.4 0.0 1.9e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CENP-H PF05837.12 KIK60802.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) LysM PF01476.20 KIK60803.1 - 2.6e-19 69.0 0.0 5.6e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 LysM domain GRDB PF07355.12 KIK60803.1 - 0.25 10.6 0.9 3.8 6.7 0.1 2.0 1 1 1 2 2 2 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) LysM PF01476.20 KIK60804.1 - 3.6e-24 84.5 0.1 1.9e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 LysM domain GRDB PF07355.12 KIK60804.1 - 0.0028 17.0 0.1 0.87 8.8 0.0 2.0 1 1 1 2 2 2 2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) LysM PF01476.20 KIK60809.1 - 1.7e-20 72.8 0.0 4e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 LysM domain Phage_CI_repr PF07022.13 KIK60809.1 - 0.04 14.0 0.1 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain HTH_3 PF01381.22 KIK60809.1 - 0.12 12.4 0.0 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix LysM PF01476.20 KIK60810.1 - 6.7e-14 51.7 0.0 5.9e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 KIK60811.1 - 1.8e-15 56.7 0.0 1.4e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 KIK60812.1 - 1e-15 57.5 0.0 5.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 LysM domain E1-E2_ATPase PF00122.20 KIK60813.1 - 4.4e-48 163.2 0.1 4.4e-48 163.2 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIK60813.1 - 1.3e-37 129.3 1.5 2.6e-37 128.3 1.5 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIK60813.1 - 9e-18 65.3 1.9 6.1e-09 36.5 0.2 3.4 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK60813.1 - 8.7e-13 48.2 0.0 3.4e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIK60813.1 - 1.4e-08 34.3 0.0 2.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK60813.1 - 5.8e-05 22.9 2.3 0.00038 20.3 1.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 KIK60813.1 - 0.001 19.0 0.2 0.0056 16.6 0.0 2.3 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC DUF2127 PF09900.9 KIK60813.1 - 0.1 12.8 0.1 0.36 11.1 0.1 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) SH3_9 PF14604.6 KIK60815.1 - 4e-06 26.6 0.1 4.3e-06 26.5 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK60815.1 - 1e-05 25.0 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 SH3 domain hSH3 PF14603.6 KIK60815.1 - 4.6e-05 23.8 0.0 5e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KIK60815.1 - 0.067 12.9 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Variant SH3 domain DNApol_Exo PF18136.1 KIK60816.1 - 0.097 11.8 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Caskin-Pro-rich PF16907.5 KIK60819.1 - 1.2 9.8 5.2 0.59 10.7 0.3 2.0 2 0 0 2 2 2 0 Proline rich region of Caskin proteins EbsA PF17255.2 KIK60823.1 - 0.0037 17.6 0.2 0.0045 17.3 0.2 1.2 1 0 0 1 1 1 1 EbsA-like protein Retrotran_gag_2 PF14223.6 KIK60824.1 - 2.4e-14 53.2 0.2 2.9e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Com_YlbF PF06133.11 KIK60824.1 - 0.083 13.5 1.2 0.12 13.0 1.2 1.2 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Xpo1 PF08389.12 KIK60825.1 - 0.11 12.5 0.4 0.35 10.9 0.1 1.7 2 0 0 2 2 2 0 Exportin 1-like protein GSK-3_bind PF05350.12 KIK60826.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding DUF4722 PF15849.5 KIK60828.1 - 0.18 11.5 0.2 0.3 10.8 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4722) RNase_H PF00075.24 KIK60832.1 - 1.8e-14 54.1 1.6 2.4e-12 47.3 1.6 2.3 1 1 0 1 1 1 1 RNase H DUF1648 PF07853.11 KIK60835.1 - 0.66 9.7 5.7 0.11 12.2 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Ank_4 PF13637.6 KIK60838.1 - 2e-42 143.0 26.5 2.8e-08 34.1 0.1 7.7 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK60838.1 - 5.2e-36 123.1 19.5 4.8e-11 43.1 0.7 4.3 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60838.1 - 1.5e-28 97.9 27.5 0.0027 18.1 0.2 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KIK60838.1 - 1.2e-27 92.9 19.1 0.0096 16.4 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KIK60838.1 - 1.8e-16 60.0 16.1 5.1e-05 23.5 0.1 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Amidinotransf PF02274.17 KIK60838.1 - 0.0032 16.6 2.2 3.3 6.7 1.0 3.6 2 1 0 2 2 2 2 Amidinotransferase Mic1 PF07035.12 KIK60838.1 - 0.12 12.1 5.3 16 5.2 0.1 4.0 2 2 2 4 4 4 0 Colon cancer-associated protein Mic1-like TOBE PF03459.17 KIK60838.1 - 0.43 10.9 3.3 64 4.0 0.0 4.5 5 0 0 5 5 5 0 TOBE domain Spore_III_AB PF09548.10 KIK60840.1 - 0.089 12.9 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF1168 PF06658.12 KIK60840.1 - 0.22 11.3 0.2 0.22 11.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) IMUP PF15761.5 KIK60840.1 - 9.2 7.0 12.6 1.9 9.2 7.7 2.0 1 1 1 2 2 2 0 Immortalisation up-regulated protein zf-C2H2 PF00096.26 KIK60841.1 - 9.8e-06 25.7 9.4 0.016 15.6 7.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK60841.1 - 0.018 15.9 8.1 0.22 12.5 4.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK60841.1 - 0.065 13.3 1.2 0.12 12.4 1.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KIK60841.1 - 1.1 9.8 5.1 0.95 9.9 2.4 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ank_4 PF13637.6 KIK60843.1 - 1.2e-15 57.6 0.0 2.1e-10 40.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK60843.1 - 5.6e-11 42.9 0.1 6.4e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK60843.1 - 5.7e-11 42.4 0.3 0.0027 18.1 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KIK60843.1 - 7.7e-09 35.1 0.0 0.0047 17.3 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KIK60843.1 - 1.2e-05 25.5 0.5 0.0014 18.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1966 PF09260.11 KIK60843.1 - 0.045 14.0 0.0 5.2 7.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) DUF3710 PF12502.8 KIK60843.1 - 0.095 12.4 0.1 2.3 7.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3710) NACHT PF05729.12 KIK60845.1 - 0.069 13.1 0.4 0.097 12.6 0.4 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIK60845.1 - 0.1 12.4 0.3 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_hydr_30_2 PF14587.6 KIK60846.1 - 1.4e-21 77.5 0.0 2.4e-20 73.5 0.0 2.0 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Phage_GPO PF05929.11 KIK60849.1 - 0.023 14.4 0.6 0.037 13.6 0.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IKI3 PF04762.12 KIK60852.1 - 2.9e-219 730.5 0.0 8.4e-118 394.7 0.0 3.1 2 1 1 3 3 3 3 IKI3 family Se-cys_synth_N PF12390.8 KIK60852.1 - 0.16 12.2 0.2 0.57 10.5 0.2 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal DUF2975 PF11188.8 KIK60853.1 - 0.98 9.3 8.9 1.3 8.9 4.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DpnI_C PF17726.1 KIK60857.1 - 0.14 12.3 0.1 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 Dam-replacing HTH domain RecQ5 PF06959.11 KIK60858.1 - 0.022 14.8 0.2 0.028 14.4 0.2 1.1 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) CxC2 PF18803.1 KIK60859.1 - 2.8e-21 75.7 1.0 4.6e-21 75.0 1.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases RNR_Alpha PF17975.1 KIK60862.1 - 0.023 15.2 0.1 0.05 14.1 0.1 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain COG2 PF06148.11 KIK60862.1 - 0.069 13.2 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4726 PF15855.5 KIK60862.1 - 0.33 11.2 2.3 0.41 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) zf-MYND PF01753.18 KIK60863.1 - 1.1e-07 31.9 7.0 1.9e-07 31.0 7.0 1.4 1 0 0 1 1 1 1 MYND finger PHD PF00628.29 KIK60865.1 - 1.5e-05 24.8 6.2 1.5e-05 24.8 6.2 2.0 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KIK60865.1 - 0.0032 17.7 2.2 0.0045 17.2 0.1 2.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIK60865.1 - 0.02 15.1 1.3 0.067 13.4 0.7 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain Efg1 PF10153.9 KIK60867.1 - 6.7e-36 123.1 13.4 6.7e-36 123.1 13.4 2.4 3 0 0 3 3 3 1 rRNA-processing protein Efg1 BTB PF00651.31 KIK60868.1 - 3.7e-06 27.1 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain SPX PF03105.19 KIK60868.1 - 0.017 15.1 0.0 0.17 11.7 0.0 2.1 1 1 0 1 1 1 0 SPX domain DUF2273 PF10031.9 KIK60869.1 - 0.11 12.5 2.9 0.19 11.8 2.9 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) EMC1_C PF07774.13 KIK60871.1 - 2.4e-60 203.9 0.1 4.2e-60 203.1 0.1 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal EMC1_C PF07774.13 KIK60873.1 - 1.9e-76 256.5 0.4 3.5e-76 255.6 0.4 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KIK60873.1 - 1.1e-08 35.0 6.1 0.0014 18.3 0.4 3.6 3 2 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KIK60873.1 - 0.0022 17.8 0.3 0.26 11.3 0.1 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat F-box-like PF12937.7 KIK60874.1 - 3e-07 30.2 0.2 5.6e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like NLE PF08154.12 KIK60875.1 - 6.5e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KIK60875.1 - 4.5e-13 49.5 22.0 0.22 12.5 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KIK60875.1 - 0.00011 21.0 0.3 0.0081 14.8 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 zf-CSL PF05207.13 KIK60878.1 - 0.043 13.5 2.3 0.089 12.5 2.3 1.5 1 0 0 1 1 1 0 CSL zinc finger UPF0547 PF10571.9 KIK60878.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PseudoU_synth_2 PF00849.22 KIK60879.1 - 1.2e-27 96.9 0.0 1.8e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPP_enzyme_N PF02776.18 KIK60882.1 - 4.1e-55 186.0 0.0 1.8e-54 183.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIK60882.1 - 1.4e-45 154.8 0.2 2.6e-44 150.7 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK60882.1 - 4.7e-41 139.7 0.3 1.7e-40 137.9 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain GTP_EFTU PF00009.27 KIK60884.1 - 1.6e-66 223.6 0.6 2.2e-66 223.1 0.6 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIK60884.1 - 1.9e-33 114.8 0.0 9.5e-33 112.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KIK60884.1 - 1.1e-23 83.0 0.0 2.4e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIK60884.1 - 3.2e-14 52.7 0.0 7.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIK60884.1 - 9.5e-13 48.3 0.0 3.1e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK60884.1 - 1.8e-06 28.0 0.3 4.4e-06 26.8 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TPP_enzyme_N PF02776.18 KIK60885.1 - 1.9e-55 187.1 0.0 1.5e-54 184.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIK60885.1 - 1.4e-44 151.6 0.6 2e-43 147.8 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK60885.1 - 3.7e-41 140.1 0.3 1.4e-40 138.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain B12-binding PF02310.19 KIK60885.1 - 0.052 13.6 0.0 4.1 7.5 0.0 3.5 4 0 0 4 4 4 0 B12 binding domain Aminotran_5 PF00266.19 KIK60886.1 - 2e-20 73.1 0.0 4.9e-18 65.2 0.0 2.9 3 0 0 3 3 3 2 Aminotransferase class-V DUF5549 PF17703.1 KIK60886.1 - 0.092 12.4 0.0 1.9 8.1 0.0 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5549) p450 PF00067.22 KIK60887.1 - 2e-49 168.6 0.0 2.7e-34 118.7 0.1 2.5 2 1 0 2 2 2 2 Cytochrome P450 DUF1796 PF08795.10 KIK60887.1 - 0.054 13.5 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) p450 PF00067.22 KIK60888.1 - 6.1e-60 203.3 0.1 1.3e-30 106.6 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 Dioxygenase_N PF04444.14 KIK60888.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus DASH_Duo1 PF08651.10 KIK60888.1 - 0.083 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 p450 PF00067.22 KIK60889.1 - 1.6e-73 248.1 0.0 5.7e-73 246.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Pkinase_fungal PF17667.1 KIK60891.1 - 1.6e-51 175.4 0.0 2.4e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK60891.1 - 0.00018 21.0 0.0 0.00068 19.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain PQ-loop PF04193.14 KIK60892.1 - 9.3e-32 108.6 3.8 1.2e-15 57.0 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK60892.1 - 0.0091 16.8 1.8 0.36 11.6 0.1 2.8 2 1 1 3 3 3 1 ER lumen protein retaining receptor HlyIII PF03006.20 KIK60892.1 - 0.067 12.9 4.2 0.11 12.2 3.9 1.5 1 1 0 1 1 1 0 Haemolysin-III related DUF3180 PF11377.8 KIK60892.1 - 0.23 11.6 3.7 7.5 6.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) LAB_N PF07578.11 KIK60892.1 - 7.6 6.7 7.9 18 5.5 0.2 2.8 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain PQ-loop PF04193.14 KIK60894.1 - 3.3e-31 106.8 4.2 5.6e-15 54.8 0.6 2.8 2 1 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK60894.1 - 0.0068 17.2 0.4 0.44 11.3 0.0 2.6 2 1 0 2 2 2 1 ER lumen protein retaining receptor MtN3_slv PF03083.16 KIK60894.1 - 0.073 13.1 3.4 3.3 7.8 0.3 2.8 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Herpes_US9 PF06072.11 KIK60894.1 - 0.11 12.4 2.0 1 9.3 0.2 2.7 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 HlyIII PF03006.20 KIK60894.1 - 0.42 10.3 3.7 0.13 11.9 0.6 1.7 2 0 0 2 2 2 0 Haemolysin-III related PQ-loop PF04193.14 KIK60896.1 - 3.8e-32 109.9 2.0 5.2e-15 55.0 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK60896.1 - 0.0085 16.9 0.4 0.87 10.4 0.0 2.6 2 1 0 2 2 2 1 ER lumen protein retaining receptor MtN3_slv PF03083.16 KIK60896.1 - 0.068 13.2 1.7 2.4 8.3 0.2 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange HlyIII PF03006.20 KIK60896.1 - 0.14 11.9 1.5 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Haemolysin-III related Herpes_US9 PF06072.11 KIK60896.1 - 2.1 8.3 3.8 3.8 7.4 0.1 2.6 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 PQ-loop PF04193.14 KIK60897.1 - 7.5e-31 105.7 2.9 2.1e-14 53.0 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK60897.1 - 0.0083 17.0 0.4 0.15 12.8 0.0 2.6 2 1 0 2 2 2 1 ER lumen protein retaining receptor CBM_1 PF00734.18 KIK60898.1 - 1.9e-12 46.9 11.6 4.4e-12 45.7 11.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KIK60898.1 - 7.9e-10 39.4 0.8 1.2e-09 38.9 0.8 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK60898.1 - 2.5e-06 27.6 0.0 4.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.22 KIK60899.1 - 4.7e-13 48.7 0.0 5.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK60900.1 - 0.0027 16.5 0.1 0.011 14.5 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 Retrotran_gag_2 PF14223.6 KIK60901.1 - 1.9e-11 43.8 0.7 2.4e-11 43.5 0.7 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DEC-1_N PF04625.13 KIK60901.1 - 2.8 6.8 5.6 3 6.8 5.6 1.3 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region PQ-loop PF04193.14 KIK60902.1 - 9.9e-31 105.3 2.6 6.4e-15 54.7 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK60902.1 - 0.0025 18.6 0.2 0.22 12.3 0.0 2.6 2 1 0 2 2 2 1 ER lumen protein retaining receptor NNMT_PNMT_TEMT PF01234.17 KIK60903.1 - 0.034 13.3 0.1 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CBM_1 PF00734.18 KIK60904.1 - 1.6e-14 53.5 12.2 2.9e-14 52.7 12.2 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KIK60905.1 - 7.6e-07 29.7 0.5 1.1e-06 29.2 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK60905.1 - 0.0017 18.3 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SCO1-SenC PF02630.14 KIK60905.1 - 0.058 13.3 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC p450 PF00067.22 KIK60906.1 - 1.6e-68 231.5 0.0 5.1e-68 229.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Esterase_phd PF10503.9 KIK60907.1 - 8e-25 87.6 0.1 1.1e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KIK60907.1 - 4.7e-13 48.8 8.8 4.7e-13 48.8 8.8 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KIK60907.1 - 6.6e-10 38.8 1.0 9.9e-10 38.2 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIK60907.1 - 0.014 15.0 1.7 0.022 14.4 1.2 1.6 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.28 KIK60907.1 - 0.046 12.6 0.2 0.065 12.1 0.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family GLTP PF08718.11 KIK60909.1 - 0.08 13.2 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF4040 PF13244.6 KIK60909.1 - 0.1 12.8 0.3 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) SRP72 PF08492.12 KIK60909.1 - 3 8.3 4.4 0.71 10.3 0.7 1.8 2 0 0 2 2 2 0 SRP72 RNA-binding domain Peptidase_S28 PF05577.12 KIK60910.1 - 9.6e-49 166.3 0.0 4e-48 164.3 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KIK60910.1 - 0.0017 17.1 0.0 0.0033 16.2 0.0 1.5 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 KIK60910.1 - 0.0077 15.7 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DegS PF05384.11 KIK60911.1 - 0.021 14.3 0.3 0.035 13.6 0.3 1.3 1 0 0 1 1 1 0 Sensor protein DegS MOLO1 PF17175.4 KIK60920.1 - 0.016 15.4 0.1 0.11 12.7 0.1 1.9 1 1 1 2 2 2 0 Modulator of levamisole receptor-1 Herpes_UL16 PF03044.14 KIK60920.1 - 0.036 13.4 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family zf-MYND PF01753.18 KIK60921.1 - 0.00056 19.9 19.1 0.0017 18.4 19.1 1.9 1 0 0 1 1 1 1 MYND finger HEPN_DZIP3 PF18738.1 KIK60921.1 - 0.019 14.7 0.1 0.065 13.0 0.1 1.9 1 1 0 1 1 1 0 DZIP3/ hRUL138-like HEPN DNA_pol_phi PF04931.13 KIK60922.1 - 3.4 5.6 6.9 4.2 5.3 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KIK60922.1 - 4.4 5.4 6.6 4.9 5.2 6.6 1.0 1 0 0 1 1 1 0 Nop14-like family Arm PF00514.23 KIK60924.1 - 3.6e-56 185.6 15.0 4.1e-12 45.7 0.3 9.1 8 1 1 9 9 9 7 Armadillo/beta-catenin-like repeat IBB PF01749.20 KIK60924.1 - 8.3e-18 64.6 1.0 2.2e-17 63.3 1.0 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KIK60924.1 - 9.9e-14 50.6 0.5 2.6e-13 49.3 0.5 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KIK60924.1 - 7.8e-12 45.4 2.2 3.4e-07 30.6 0.1 4.4 2 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KIK60924.1 - 2.6e-11 43.7 0.1 0.00036 20.9 0.0 4.8 4 1 0 4 4 4 2 HEAT repeats Malate_synthase PF01274.22 KIK60924.1 - 5.4e-07 28.3 0.0 8.6e-07 27.6 0.0 1.2 1 0 0 1 1 1 1 Malate synthase HEAT PF02985.22 KIK60924.1 - 1.2e-06 28.3 0.1 0.23 11.8 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat V-ATPase_H_C PF11698.8 KIK60924.1 - 0.0025 17.9 0.2 2.6 8.2 0.0 3.6 3 1 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 KIK60924.1 - 0.0035 16.9 1.5 2.1 7.8 0.6 3.3 3 0 0 3 3 3 1 Armadillo-like HEAT_PBS PF03130.16 KIK60924.1 - 0.045 14.4 0.8 2.1 9.3 0.1 3.4 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat Neuraminidase PF18413.1 KIK60924.1 - 0.19 11.4 0.5 0.34 10.6 0.5 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain RICTOR_V PF14668.6 KIK60924.1 - 0.27 11.5 4.0 4.9 7.5 0.1 3.5 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3948 PF13134.6 KIK60924.1 - 0.36 10.6 2.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Abhydrolase_1 PF00561.20 KIK60925.1 - 1.2e-14 54.6 0.0 4.2e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK60925.1 - 0.00036 19.9 0.0 0.00091 18.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIK60925.1 - 0.00048 19.7 0.0 0.002 17.6 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.14 KIK60925.1 - 0.051 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family PUA_3 PF17785.1 KIK60929.1 - 0.12 12.1 0.0 1.2 9.0 0.0 2.5 2 1 0 2 2 2 0 PUA-like domain KOW PF00467.29 KIK60929.1 - 0.24 11.4 4.1 2.2 8.4 0.7 2.7 2 0 0 2 2 2 0 KOW motif zf-RING_UBOX PF13445.6 KIK60930.1 - 8e-07 29.0 9.6 1.3e-06 28.3 8.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK60930.1 - 1.2e-05 25.0 10.2 0.00014 21.7 11.3 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK60930.1 - 4.1e-05 23.4 12.6 8.1e-05 22.4 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK60930.1 - 0.00019 21.5 13.7 0.0004 20.5 13.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIK60930.1 - 0.00022 21.1 11.6 0.00042 20.2 11.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK60930.1 - 0.0068 16.7 10.7 0.015 15.6 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK60930.1 - 0.02 14.7 10.0 0.038 13.9 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KIK60930.1 - 0.25 11.5 6.2 0.64 10.2 6.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 KIK60930.1 - 0.37 10.9 8.2 2.9 8.1 8.1 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KIK60930.1 - 0.72 9.8 3.3 1.5 8.7 3.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIK60930.1 - 4.2 7.3 11.1 20 5.1 11.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DDE_1 PF03184.19 KIK60931.1 - 0.0002 21.0 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIK60932.1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease TcfC PF16967.5 KIK60939.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 E-set like domain GvpL_GvpF PF06386.11 KIK60943.1 - 0.007 16.3 0.9 0.0083 16.1 0.9 1.1 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF Spectrin_like PF18373.1 KIK60943.1 - 0.016 15.2 0.5 0.04 14.0 0.2 1.9 2 0 0 2 2 2 0 Spectrin like domain DUF484 PF04340.12 KIK60943.1 - 0.034 13.8 2.0 0.045 13.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Elf4 PF07011.11 KIK60943.1 - 0.062 13.2 2.5 0.16 11.9 0.2 2.1 2 0 0 2 2 2 0 Early Flowering 4 domain DEC-1_N PF04625.13 KIK60946.1 - 1.4 7.9 5.1 1.8 7.5 5.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CDC45 PF02724.14 KIK60947.1 - 7.9 4.6 12.3 10 4.3 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2461 PF09365.10 KIK60949.1 - 3.4e-75 252.6 0.0 5.2e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PBP1_TM PF14812.6 KIK60949.1 - 1.8 9.0 37.1 4.5 7.7 10.9 3.5 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_11 PF13414.6 KIK60953.1 - 3e-17 62.0 2.7 0.46 10.2 0.0 9.6 10 0 0 10 10 10 4 TPR repeat TPR_1 PF00515.28 KIK60953.1 - 6.5e-13 47.9 18.6 0.015 15.1 0.3 9.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK60953.1 - 4.9e-12 46.0 17.0 0.033 14.5 0.3 9.2 8 3 2 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK60953.1 - 6.5e-12 44.7 0.2 0.16 12.2 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60953.1 - 3.5e-09 36.1 11.6 0.4 10.9 0.3 9.1 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK60953.1 - 4.7e-07 30.1 1.5 2.9 9.0 0.1 7.1 10 0 0 10 10 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK60953.1 - 1.5e-05 24.7 11.9 1.6 8.7 0.0 8.5 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK60953.1 - 2.4e-05 23.9 0.9 0.003 17.0 0.1 2.8 1 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KIK60953.1 - 0.00073 19.4 5.2 2.3 8.4 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KIK60953.1 - 0.0013 18.7 6.3 63 3.8 0.2 7.4 9 0 0 9 9 9 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 KIK60953.1 - 0.0016 17.9 0.1 0.62 9.4 0.0 3.2 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP MAS20 PF02064.15 KIK60953.1 - 0.0069 16.5 0.4 2.2 8.4 0.0 4.5 5 0 0 5 5 5 1 MAS20 protein import receptor DUF5588 PF17826.1 KIK60953.1 - 0.015 14.2 2.2 0.11 11.3 0.1 2.9 2 1 0 3 3 3 0 Family of unknown function (DUF5588) Exonuc_VII_S PF02609.16 KIK60953.1 - 0.06 13.4 2.1 2.4 8.3 0.0 4.0 5 0 0 5 5 3 0 Exonuclease VII small subunit TPR_16 PF13432.6 KIK60953.1 - 0.12 13.0 0.3 7.8 7.2 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK60953.1 - 0.15 12.6 2.1 4.3 7.9 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK60953.1 - 1.8 8.2 7.6 38 3.9 0.1 4.1 3 1 2 5 5 5 0 26S proteasome subunit RPN7 CHAT PF12770.7 KIK60954.1 - 1.8e-29 103.1 0.0 2.5e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Peptidase_C14 PF00656.22 KIK60956.1 - 9.9e-21 74.8 0.0 1.9e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 KIK60956.1 - 0.0026 17.2 0.1 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 CHAT domain Blt1 PF12754.7 KIK60956.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain Glyco_hydro_30 PF02055.16 KIK60957.1 - 7.6e-26 90.9 4.2 1.1e-25 90.4 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIK60957.1 - 2.1e-14 53.5 1.3 3.3e-14 52.8 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KIK60957.1 - 9.5e-05 22.2 0.2 0.0082 15.8 0.1 2.3 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 KIK60957.1 - 0.00095 18.8 1.3 0.0016 18.0 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Lipase_GDSL PF00657.22 KIK60959.1 - 1e-05 25.6 0.0 3.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK60959.1 - 3.9e-05 24.1 1.6 7.1e-05 23.3 1.6 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-CCHC PF00098.23 KIK60960.1 - 4.9e-06 26.4 1.8 7.5e-06 25.8 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KIK60960.1 - 0.025 14.5 0.8 0.037 14.0 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 KIK60960.1 - 0.073 13.5 6.8 0.21 12.0 6.4 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Retrotran_gag_2 PF14223.6 KIK60961.1 - 1.3e-09 37.8 0.0 1.5e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PhoLip_ATPase_C PF16212.5 KIK60962.1 - 0.011 15.4 1.4 0.011 15.4 1.4 1.9 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Ferric_reduct PF01794.19 KIK60962.1 - 0.021 14.9 4.1 0.082 13.0 4.1 2.1 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF2561 PF10812.8 KIK60965.1 - 0.028 14.4 2.5 0.057 13.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF1129 PF06570.11 KIK60965.1 - 0.28 10.7 0.1 0.28 10.7 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) ARD PF03079.14 KIK60967.1 - 4.1e-41 140.8 0.0 4.8e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIK60967.1 - 3.7e-09 36.2 0.0 6.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIK60967.1 - 2.4e-05 24.3 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIK60967.1 - 0.0035 17.0 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KIK60967.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) F-box-like PF12937.7 KIK60968.1 - 1.2e-07 31.5 1.3 2.8e-07 30.3 1.3 1.7 1 1 0 1 1 1 1 F-box-like RNase_T PF00929.24 KIK60969.1 - 3.7e-11 43.8 0.0 7.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease HCV_capsid PF01543.17 KIK60969.1 - 0.012 15.8 1.7 0.045 13.9 1.7 2.0 1 0 0 1 1 1 0 Hepatitis C virus capsid protein AAR2 PF05282.11 KIK60969.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAR2 protein DNA_pol_A_exo1 PF01612.20 KIK60969.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 1 0 1 1 1 0 3'-5' exonuclease CHAT PF12770.7 KIK60970.1 - 1.9e-39 135.8 0.7 3.6e-39 134.9 0.7 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK60970.1 - 0.00013 21.8 2.8 0.33 10.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK60970.1 - 0.0012 18.8 0.1 1.2 9.4 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK60970.1 - 0.0086 16.8 4.6 7.1 7.7 0.0 5.6 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK60970.1 - 0.085 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 TPR repeat Alpha_L_fucos PF01120.17 KIK60972.1 - 4.3e-83 279.7 1.2 5.6e-83 279.3 1.2 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase FlgD_ig PF13860.6 KIK60972.1 - 0.12 12.2 0.2 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 FlgD Ig-like domain GMC_oxred_N PF00732.19 KIK60975.1 - 1.7e-64 218.1 0.0 2.2e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK60975.1 - 1.3e-34 119.8 0.0 2.2e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK60975.1 - 0.00078 19.6 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK60975.1 - 0.0012 18.0 1.1 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK60975.1 - 0.0077 15.3 0.5 0.0077 15.3 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KIK60975.1 - 0.064 12.8 1.1 0.14 11.7 1.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK60975.1 - 0.092 12.0 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK60975.1 - 0.51 9.1 2.2 0.36 9.6 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase ING PF12998.7 KIK60976.1 - 5.6e-17 62.2 0.3 8.1e-17 61.7 0.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIK60976.1 - 2.8e-05 23.9 6.7 4.5e-05 23.2 6.7 1.3 1 0 0 1 1 1 1 PHD-finger LegC3_N PF18654.1 KIK60976.1 - 0.024 13.9 2.0 0.038 13.2 2.0 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Metalloenzyme PF01676.18 KIK60976.1 - 0.05 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1081 PF06448.11 KIK60976.1 - 0.055 13.9 0.1 16 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1081) Lipoprotein_7 PF01540.16 KIK60976.1 - 0.056 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein N_NLPC_P60 PF12912.7 KIK60976.1 - 0.16 12.3 0.3 0.43 10.9 0.2 1.7 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term PHD_2 PF13831.6 KIK60976.1 - 0.34 10.5 3.0 0.66 9.6 3.0 1.5 1 0 0 1 1 1 0 PHD-finger Apolipoprotein PF01442.18 KIK60976.1 - 0.38 10.6 5.9 6.8 6.5 4.6 2.3 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain F-box-like PF12937.7 KIK60979.1 - 1.5e-07 31.2 1.3 4e-07 29.8 0.5 2.2 2 1 0 2 2 2 1 F-box-like RhoGAP PF00620.27 KIK60980.1 - 6.5e-44 149.4 0.0 1.5e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KIK60980.1 - 6.9e-11 42.7 0.0 6.3e-09 36.3 0.0 2.8 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIK60980.1 - 8.3e-06 26.0 0.0 9.7e-05 22.6 0.0 2.9 2 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.29 KIK60980.1 - 9.4e-06 26.1 0.0 0.001 19.6 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KIK60980.1 - 3.4e-05 24.2 0.0 0.00029 21.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain adh_short PF00106.25 KIK60982.1 - 2.7e-33 115.1 0.1 3.7e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK60982.1 - 8.3e-16 58.3 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK60982.1 - 3e-06 27.3 0.2 7.2e-06 26.0 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK60982.1 - 6.4e-06 25.8 0.0 2.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GATase_4 PF13230.6 KIK60983.1 - 4.1e-20 71.8 0.1 1.8e-19 69.7 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KIK60983.1 - 3.3e-11 43.5 0.0 8.7e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain NIF PF03031.18 KIK60987.1 - 4.8e-42 143.4 0.2 8.4e-42 142.6 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Sperm_Ag_HE2 PF05324.13 KIK60987.1 - 0.071 13.6 1.0 0.19 12.2 1.0 1.7 1 0 0 1 1 1 0 Sperm antigen HE2 adh_short PF00106.25 KIK60989.1 - 1.4e-05 24.6 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK60989.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KIK60990.1 - 0.00028 20.4 0.0 0.00028 20.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK60990.1 - 0.0025 17.4 0.0 0.0025 17.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M28 PF04389.17 KIK60992.1 - 7.9e-23 81.2 0.0 1.4e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK60992.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SLC3A2_N PF16028.5 KIK60992.1 - 8 6.1 10.6 0.057 13.0 0.6 2.6 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Trp_oprn_chp PF09534.10 KIK60994.1 - 0.05 13.4 0.4 0.055 13.3 0.4 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Trp_oprn_chp PF09534.10 KIK60995.1 - 0.015 15.1 1.7 0.022 14.6 1.7 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mito_carr PF00153.27 KIK60998.1 - 2.4e-48 162.0 0.7 7.1e-18 64.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HSP20 PF00011.21 KIK60999.1 - 3.8e-24 84.8 0.0 4.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK60999.1 - 4.2e-10 39.0 0.0 5.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 KIK60999.1 - 0.1 12.7 0.1 16 5.7 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal CS PF04969.16 KIK60999.1 - 0.1 13.6 0.0 0.14 13.2 0.0 1.2 1 0 0 1 1 1 0 CS domain BON PF04972.17 KIK60999.1 - 0.12 12.7 0.0 0.88 9.9 0.0 2.0 2 0 0 2 2 2 0 BON domain HSP20 PF00011.21 KIK61000.1 - 4.5e-24 84.5 0.7 7.9e-24 83.8 0.4 1.5 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK61000.1 - 4.3e-10 39.0 0.0 7.3e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KIK61000.1 - 0.016 16.2 0.0 0.028 15.5 0.0 1.4 1 0 0 1 1 1 0 CS domain FKBP26_C PF18046.1 KIK61000.1 - 0.083 13.0 0.1 10 6.3 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal A1_Propeptide PF07966.12 KIK61005.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 A1 Propeptide RRM_1 PF00076.22 KIK61008.1 - 9.6e-31 105.4 2.7 4.5e-09 36.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK61008.1 - 0.0001 22.3 0.1 0.41 10.7 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KIK61008.1 - 0.00023 21.0 0.0 2.7 7.9 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KIK61008.1 - 0.00029 20.4 0.0 0.058 13.0 0.0 3.1 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 KIK61008.1 - 0.036 14.7 0.0 7 7.4 0.0 3.4 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 KIK61008.1 - 0.062 13.4 0.0 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif WD40 PF00400.32 KIK61009.1 - 5.9e-15 55.4 0.5 0.072 14.0 0.0 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK61009.1 - 4.6e-05 23.6 0.0 0.1 12.9 0.0 5.4 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK61009.1 - 9.5e-05 22.2 0.1 12 6.0 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK61009.1 - 0.0042 16.1 0.5 6.5 5.6 0.0 4.2 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KIK61009.1 - 0.11 11.5 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain CC2D2AN-C2 PF15625.6 KIK61009.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain NACHT PF05729.12 KIK61010.1 - 6.9e-10 39.1 0.8 4.5e-09 36.4 0.8 2.1 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 KIK61010.1 - 1.1e-06 28.5 0.1 3.1e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KIK61010.1 - 2.6e-06 27.9 0.0 3.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61010.1 - 4.3e-06 27.0 0.0 7.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK61010.1 - 1.1e-05 25.9 0.2 2.1e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK61010.1 - 9.1e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain CobA_CobO_BtuR PF02572.15 KIK61010.1 - 0.00013 22.2 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_5 PF07728.14 KIK61010.1 - 0.00022 21.2 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ATPase PF06745.13 KIK61010.1 - 0.01 15.2 0.6 0.027 13.8 0.6 1.6 1 1 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 KIK61010.1 - 0.015 14.6 1.5 0.038 13.2 0.8 1.8 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.13 KIK61010.1 - 0.017 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KIK61010.1 - 0.033 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK61010.1 - 0.072 13.1 0.2 0.53 10.3 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK61010.1 - 0.087 13.4 0.3 0.85 10.2 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK61010.1 - 0.12 11.9 0.1 0.53 9.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIK61010.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Goodbye PF17109.5 KIK61011.1 - 0.021 15.3 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain ABC_tran_CTD PF16326.5 KIK61011.1 - 0.034 14.4 0.1 0.1 12.9 0.1 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain HisKA PF00512.25 KIK61011.1 - 0.12 12.5 0.4 2.5 8.2 0.0 2.7 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Ldr_toxin PF13940.6 KIK61014.1 - 1.1 9.4 5.2 0.58 10.3 2.7 1.8 2 1 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Helicase_C PF00271.31 KIK61015.1 - 5e-07 30.1 0.0 1.6e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK61015.1 - 7.4e-06 25.8 0.1 3.2e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK61015.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NUDE_C PF04880.13 KIK61016.1 - 3.8 8.0 5.1 5.8 7.4 5.1 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region HMG_box PF00505.19 KIK61017.1 - 3.5e-14 53.0 1.4 7.3e-14 51.9 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK61017.1 - 1.2e-05 25.8 0.3 3.1e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain Nnf1 PF03980.14 KIK61019.1 - 0.0056 17.0 0.1 0.0078 16.6 0.1 1.1 1 0 0 1 1 1 1 Nnf1 XRN_N PF03159.18 KIK61019.1 - 0.0098 15.3 1.7 0.012 15.0 1.7 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ATP-synt_C PF00137.21 KIK61020.1 - 0.04 14.3 1.4 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 ATP synthase subunit C Rax2 PF12768.7 KIK61020.1 - 0.067 12.6 0.1 0.097 12.1 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2768 PF10966.8 KIK61020.1 - 0.92 10.0 8.5 0.46 11.0 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) Pkinase PF00069.25 KIK61021.1 - 0.0022 17.4 0.0 0.0024 17.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK61021.1 - 0.031 14.2 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_1 PF00036.32 KIK61023.1 - 1.5e-24 83.6 2.3 7.2e-07 28.3 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KIK61023.1 - 8.2e-23 78.3 1.3 6.5e-07 28.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KIK61023.1 - 6.2e-21 74.6 0.3 1.8e-09 37.9 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIK61023.1 - 9.7e-19 66.0 1.5 2.4e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIK61023.1 - 1.2e-12 47.4 6.2 3.1e-05 23.7 0.1 5.2 3 3 2 5 5 5 5 EF-hand domain pair OTT_1508_deam PF14441.6 KIK61024.1 - 0.00069 19.6 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase KN_motif PF12075.8 KIK61025.1 - 0.031 14.1 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 KN motif Shisa PF13908.6 KIK61026.1 - 1.8 8.8 5.5 8.6 6.6 5.7 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Aminotran_5 PF00266.19 KIK61027.1 - 8.8e-17 61.1 0.1 2.6e-16 59.6 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIK61027.1 - 2e-05 24.0 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK61027.1 - 0.00057 18.5 0.0 0.0017 17.0 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Phage_spike_2 PF18781.1 KIK61027.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Phage spike trimer DegT_DnrJ_EryC1 PF01041.17 KIK61027.1 - 0.15 11.3 0.5 1.3 8.3 0.5 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FIBP PF05427.11 KIK61027.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) Bromodomain PF00439.25 KIK61029.1 - 4.6e-20 71.5 0.1 2.9e-19 68.9 0.1 2.3 1 1 1 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KIK61029.1 - 2.3e-05 24.3 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Pkinase_fungal PF17667.1 KIK61031.1 - 9.8e-46 156.3 0.0 3.9e-45 154.3 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK61031.1 - 0.00018 21.0 0.0 0.00047 19.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain NOA36 PF06524.12 KIK61031.1 - 2.7 7.2 7.4 4.7 6.4 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 KIK61031.1 - 3.2 6.8 7.2 5.4 6.1 7.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein AROS PF15684.5 KIK61031.1 - 7.3 7.2 9.7 0.11 13.0 1.4 2.3 2 1 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 ABC2_membrane PF01061.24 KIK61032.1 - 8.4e-76 254.1 49.9 4.6e-40 137.3 16.8 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIK61032.1 - 7.6e-38 130.1 0.0 8.6e-18 65.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIK61032.1 - 9.6e-35 118.4 14.8 2.3e-29 101.1 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK61032.1 - 1.8e-18 66.9 0.1 5.4e-18 65.4 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KIK61032.1 - 1e-07 32.3 0.1 0.012 15.9 0.1 3.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK61032.1 - 1.2e-07 32.3 0.1 0.00075 19.9 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK61032.1 - 1.3e-06 28.4 0.2 0.00011 22.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KIK61032.1 - 1.5e-05 24.7 0.1 0.00072 19.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KIK61032.1 - 9e-05 21.7 54.7 0.0038 16.4 27.5 4.0 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KIK61032.1 - 0.00014 21.2 10.0 0.00014 21.2 10.0 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KIK61032.1 - 0.00017 21.6 0.1 0.047 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK61032.1 - 0.00033 20.4 0.4 0.24 11.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KIK61032.1 - 0.00046 20.1 0.4 0.13 12.1 0.3 2.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KIK61032.1 - 0.00094 19.7 0.0 0.18 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIK61032.1 - 0.0013 18.8 0.2 0.69 10.0 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KIK61032.1 - 0.0063 16.7 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIK61032.1 - 0.0064 16.0 0.0 0.16 11.4 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIK61032.1 - 0.012 15.3 0.3 1.3 8.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK61032.1 - 0.015 14.9 1.9 0.45 10.1 0.7 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KIK61032.1 - 0.015 14.5 0.0 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KIK61032.1 - 0.027 14.7 0.4 2.1 8.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK61032.1 - 0.029 14.7 0.0 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 KIK61032.1 - 0.032 13.5 0.0 8.3 5.6 0.2 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 KIK61032.1 - 0.05 14.0 0.0 8.9 6.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK61032.1 - 0.054 13.4 0.1 16 5.4 0.2 2.8 3 0 0 3 3 3 0 NTPase SbcCD_C PF13558.6 KIK61032.1 - 0.1 12.8 0.1 6 7.2 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.6 KIK61032.1 - 0.11 12.9 0.1 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK61032.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KIK61032.1 - 0.16 11.8 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 KIK61032.1 - 0.21 11.6 1.3 0.54 10.3 0.1 2.2 3 0 0 3 3 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 KIK61032.1 - 0.22 10.3 0.2 0.44 9.3 0.2 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PduV-EutP PF10662.9 KIK61032.1 - 0.27 11.0 0.8 5.5 6.7 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2188 PF09954.9 KIK61035.1 - 0.029 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Mod_r PF07200.13 KIK61036.1 - 0.013 15.6 0.1 0.99 9.5 0.0 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TUG-UBL1 PF11470.8 KIK61036.1 - 0.036 14.3 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain Carb_kinase PF01256.17 KIK61036.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase DUF918 PF06033.11 KIK61036.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) WD40 PF00400.32 KIK61038.1 - 2e-17 63.2 17.7 9.1e-05 23.2 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK61038.1 - 6.2e-13 48.9 2.4 3.5e-05 24.0 0.1 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK61038.1 - 0.00052 20.0 0.1 0.036 13.9 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK61038.1 - 0.14 11.0 0.1 0.67 8.9 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK61040.1 - 4.2e-11 43.1 0.7 1.7e-10 41.1 0.2 2.3 2 1 0 2 2 1 1 NACHT domain WD40 PF00400.32 KIK61040.1 - 3e-08 34.2 2.6 0.35 11.8 0.0 5.5 6 0 0 6 6 4 2 WD domain, G-beta repeat AAA_22 PF13401.6 KIK61040.1 - 7.8e-08 32.7 0.3 7.5e-07 29.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIK61040.1 - 1.1e-05 25.9 0.2 8e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KIK61040.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK61040.1 - 0.0035 16.6 0.0 0.0068 15.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 KIK61040.1 - 0.0038 16.8 0.0 2.9 7.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KIK61040.1 - 0.0079 16.6 0.0 0.022 15.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIK61040.1 - 0.0091 15.4 0.0 0.079 12.4 0.0 2.2 1 1 0 1 1 1 1 Bacterial TniB protein ANAPC4_WD40 PF12894.7 KIK61040.1 - 0.013 15.8 1.5 0.3 11.4 0.0 3.9 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain IstB_IS21 PF01695.17 KIK61040.1 - 0.022 14.5 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 KIK61040.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 KIK61040.1 - 0.19 11.7 0.2 39 4.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KIK61040.1 - 0.2 12.1 0.3 3.2 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KIK61041.1 - 4.5e-80 269.6 0.0 6.1e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KIK61041.1 - 2.1e-26 92.9 0.0 3.3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIK61041.1 - 1.5e-23 83.6 0.0 3.4e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KIK61041.1 - 3.1e-08 34.2 0.0 8.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIK61041.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain ALO PF04030.14 KIK61043.1 - 1.2e-28 100.7 1.2 1.7e-28 100.2 1.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK61043.1 - 1.4e-22 79.9 0.0 2.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.7 KIK61045.1 - 5.4e-08 32.6 2.8 2.3e-07 30.6 0.6 2.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK61045.1 - 0.11 12.9 1.5 23 5.6 0.1 3.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) 2OG-FeII_Oxy PF03171.20 KIK61046.1 - 0.0026 18.2 0.0 0.0073 16.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK61046.1 - 0.027 15.2 0.0 0.057 14.2 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal NAD_kinase PF01513.21 KIK61049.1 - 3.4e-62 210.3 0.0 4.6e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KIK61049.1 - 0.034 13.7 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain IPK PF03770.16 KIK61050.1 - 3.5e-55 186.9 0.0 4.9e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase TPR_12 PF13424.6 KIK61054.1 - 3e-08 33.8 3.2 2.2e-06 27.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK61054.1 - 2.7e-06 27.1 4.1 0.021 14.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KIK61054.1 - 0.011 15.5 0.4 0.3 10.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KIK61054.1 - 0.015 15.5 0.5 0.065 13.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3895 PF13034.6 KIK61054.1 - 0.018 15.0 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) TPR_1 PF00515.28 KIK61054.1 - 0.035 13.9 3.7 0.042 13.7 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK61054.1 - 0.072 13.9 0.9 16 6.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK61054.1 - 0.15 12.1 0.2 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 KIK61054.1 - 0.16 11.4 0.8 7.6 5.9 0.1 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 KIK61054.1 - 1.3 9.3 4.1 16 5.8 0.5 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PAP2_3 PF14378.6 KIK61055.1 - 3.8e-23 82.2 15.7 3.8e-23 82.2 15.7 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KIK61055.1 - 5.4e-07 29.5 7.3 5.4e-07 29.5 7.3 2.3 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 KIK61055.1 - 1.4 9.5 9.8 0.24 12.0 4.6 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal EthD PF07110.11 KIK61056.1 - 0.0093 17.1 0.0 0.041 15.0 0.0 2.0 1 1 0 1 1 1 1 EthD domain Fungal_lectin PF07938.12 KIK61059.1 - 8.3e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal fucose-specific lectin Glyco_hydro_31 PF01055.26 KIK61061.1 - 2e-141 472.2 3.8 3.2e-141 471.5 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIK61061.1 - 1.8e-17 63.4 0.1 5.9e-17 61.7 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KIK61061.1 - 1.6e-05 25.1 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Prot_ATP_OB_N PF17758.1 KIK61061.1 - 0.029 14.0 0.1 0.1 12.3 0.1 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain FMO-like PF00743.19 KIK61062.1 - 6.1e-18 64.5 0.0 1.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK61062.1 - 8.6e-11 41.9 0.0 1.5e-08 34.7 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK61062.1 - 9.1e-11 41.5 0.0 1.5e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK61062.1 - 9.8e-11 41.4 0.0 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK61062.1 - 4.2e-07 29.4 0.0 7.7e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK61062.1 - 7.9e-07 29.6 0.0 0.031 14.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK61062.1 - 0.00031 19.5 0.1 0.93 8.1 0.0 3.3 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 KIK61062.1 - 0.00039 20.1 1.1 1.4 8.4 0.0 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK61062.1 - 0.00045 20.2 0.1 2.5 8.1 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 KIK61062.1 - 0.0012 18.2 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KIK61062.1 - 0.0017 17.4 0.0 0.11 11.5 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIK61062.1 - 0.005 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK61062.1 - 0.018 14.4 0.0 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIK61062.1 - 0.082 13.4 0.0 4.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 KIK61062.1 - 0.089 12.1 0.0 2.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KIK61062.1 - 0.15 11.1 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KIK61062.1 - 0.18 10.9 0.1 19 4.2 0.0 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A N2227 PF07942.12 KIK61063.1 - 1e-61 208.5 0.0 2.2e-61 207.4 0.0 1.5 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KIK61063.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61063.1 - 0.0019 18.8 0.0 0.13 12.9 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK61063.1 - 0.0024 18.6 0.0 0.011 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61063.1 - 0.0025 18.4 0.0 0.2 12.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61063.1 - 0.061 13.1 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_22 PF13383.6 KIK61066.1 - 1.4e-21 77.2 0.0 1.8e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KIK61066.1 - 4e-11 43.2 0.0 5.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 KIK61067.1 - 5.8e-20 71.9 0.0 7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KIK61067.1 - 4e-08 33.5 0.0 5.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain FCH PF00611.23 KIK61068.1 - 1.1e-17 64.1 0.0 5.7e-17 61.8 0.0 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIK61068.1 - 4.8e-10 38.9 0.1 9.1e-10 38.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK61068.1 - 3e-08 33.4 0.1 5.8e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK61068.1 - 0.00028 20.5 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK61069.1 - 6.6e-12 44.9 0.1 1.2e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK61069.1 - 4.5e-09 36.0 0.1 7.5e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK61069.1 - 2.9e-06 26.9 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK61070.1 - 1.1e-24 85.7 0.6 5e-12 45.2 0.1 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KIK61070.1 - 1e-19 70.1 1.9 2.8e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KIK61070.1 - 3.1e-14 52.4 0.0 2.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain TrkA_C PF02080.21 KIK61070.1 - 0.0063 16.3 0.1 0.47 10.3 0.0 2.6 3 0 0 3 3 3 1 TrkA-C domain CD99L2 PF12301.8 KIK61071.1 - 0.015 15.6 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF5081 PF16887.5 KIK61072.1 - 0.048 12.7 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) Dehydratase_hem PF13816.6 KIK61073.1 - 0.034 13.6 0.0 0.039 13.4 0.0 1.0 1 0 0 1 1 1 0 Haem-containing dehydratase SWIB PF02201.18 KIK61074.1 - 0.098 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain DUF648 PF04890.13 KIK61075.1 - 0.028 14.2 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) HR1 PF02185.16 KIK61075.1 - 0.03 14.5 2.5 0.058 13.5 2.5 1.6 1 1 0 1 1 1 0 Hr1 repeat TPX2 PF06886.11 KIK61075.1 - 0.4 11.0 4.1 0.64 10.3 4.1 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) PKcGMP_CC PF16808.5 KIK61076.1 - 0.00072 19.4 4.2 0.37 10.7 0.8 2.7 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK61076.1 - 0.033 14.3 0.4 0.051 13.6 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Csm1_N PF18504.1 KIK61076.1 - 1.7 9.0 8.7 2.3 8.6 0.3 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain Clat_adaptor_s PF01217.20 KIK61080.1 - 3.9e-16 59.3 0.0 6.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_5 PF13306.6 KIK61082.1 - 0.28 11.1 1.7 0.64 10.0 0.3 2.2 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) zf-CHY PF05495.12 KIK61085.1 - 1.7e-14 54.1 15.8 4e-14 52.8 15.8 1.6 1 1 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 KIK61085.1 - 0.0022 17.8 6.1 0.97 9.4 0.0 3.2 2 1 1 3 3 3 2 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KIK61085.1 - 0.022 14.7 9.9 1.7 8.7 6.2 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cys_rich_KTR PF14205.6 KIK61085.1 - 0.15 11.9 6.9 3.3 7.6 0.1 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR SP2 PF03014.14 KIK61085.1 - 0.24 9.8 0.4 0.26 9.7 0.4 1.0 1 0 0 1 1 1 0 Structural protein 2 DpnI PF06044.12 KIK61085.1 - 0.75 9.4 5.7 0.59 9.7 2.0 1.9 1 1 1 2 2 2 0 Dam-replacing family NOB1_Zn_bind PF08772.11 KIK61085.1 - 0.9 9.7 8.5 0.12 12.5 4.3 1.8 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 KIK61085.1 - 1.1 9.3 10.8 0.85 9.7 7.5 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Evr1_Alr PF04777.13 KIK61085.1 - 4.3 7.9 9.3 21 5.7 9.3 2.2 1 1 0 1 1 1 0 Erv1 / Alr family F-box-like PF12937.7 KIK61087.1 - 0.00037 20.3 0.3 0.00037 20.3 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK61088.1 - 1.2e-09 37.9 1.4 1.4e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK61088.1 - 0.033 14.1 0.4 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 F-box domain YccV-like PF08755.11 KIK61088.1 - 0.21 12.1 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KIK61090.1 - 3.5e-09 36.4 0.1 3.5e-09 36.4 0.1 2.6 3 0 0 3 3 3 1 F-box-like DUF4351 PF14261.6 KIK61092.1 - 0.027 14.5 0.1 0.06 13.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) Porphobil_deam PF01379.20 KIK61093.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain GATA PF00320.27 KIK61095.1 - 2.2e-24 84.7 18.4 1.3e-12 47.1 6.2 2.8 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KIK61095.1 - 4e-11 42.6 0.4 8.7e-11 41.5 0.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KIK61095.1 - 0.00059 19.9 2.7 0.27 11.4 0.3 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Cytochrom_c3_2 PF14537.6 KIK61095.1 - 0.017 15.6 2.8 0.57 10.7 0.5 2.7 2 0 0 2 2 2 0 Cytochrome c3 HypA PF01155.19 KIK61095.1 - 0.023 14.7 1.7 0.42 10.6 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 KIK61095.1 - 0.03 14.4 1.4 1 9.4 0.2 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TDP43_N PF18694.1 KIK61095.1 - 0.052 13.4 0.1 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 KIK61095.1 - 0.28 11.2 6.8 4.6 7.3 7.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KIK61095.1 - 0.71 9.8 7.0 4.7 7.1 1.5 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 KIK61095.1 - 0.92 9.5 6.7 3.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cytochrome_C7 PF14522.6 KIK61095.1 - 3.2 7.8 9.5 4.4 7.4 6.0 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Auto_anti-p27 PF06677.12 KIK61095.1 - 4.2 7.6 6.2 4.6 7.5 1.1 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) FOXP-CC PF16159.5 KIK61097.1 - 0.92 10.2 5.6 2.1 9.0 0.3 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIK61097.1 - 1.3 10.0 7.1 61 4.9 0.5 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK61098.1 - 0.00088 19.9 7.5 0.16 12.6 0.1 3.1 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIK61098.1 - 0.036 14.9 17.5 0.054 14.3 4.5 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIK61098.1 - 3.3 7.8 5.6 7.8 6.6 0.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KIK61100.1 - 5.9e-05 23.6 11.4 0.012 16.4 3.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK61100.1 - 0.00031 21.3 6.6 0.093 13.4 0.2 2.8 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK61100.1 - 0.0036 17.7 11.4 0.11 13.0 3.8 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type Toxin_8 PF07365.12 KIK61100.1 - 0.033 14.4 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 Alpha conotoxin precursor zf-C2H2_8 PF15909.5 KIK61100.1 - 0.047 14.0 0.6 0.22 11.8 0.5 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon FAD_binding_3 PF01494.19 KIK61102.1 - 4.8e-26 91.8 0.0 2.2e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK61102.1 - 1.1e-05 25.5 1.1 2.9e-05 24.2 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK61102.1 - 2.1e-05 23.6 0.1 4.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK61102.1 - 0.00059 19.2 0.3 0.003 16.9 0.2 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK61102.1 - 0.003 17.6 0.3 1.5 8.8 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KIK61102.1 - 0.0036 17.0 1.6 0.015 14.9 0.7 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KIK61102.1 - 0.0052 15.9 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 KIK61102.1 - 0.0059 17.1 0.2 0.11 13.0 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK61102.1 - 0.027 13.7 0.0 0.069 12.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KIK61102.1 - 0.33 10.0 3.2 0.53 9.3 3.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIK61102.1 - 0.48 9.1 1.6 1.1 7.9 1.1 1.7 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KIK61103.1 - 5e-39 134.0 6.1 1.5e-36 126.0 6.1 3.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIK61103.1 - 5.8e-32 110.2 0.0 1.1e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain OCD_Mu_crystall PF02423.15 KIK61103.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF2680 PF10925.8 KIK61103.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) NAD_binding_2 PF03446.15 KIK61103.1 - 0.13 12.4 0.9 0.87 9.7 0.5 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_3_C PF01915.22 KIK61104.1 - 6.7e-52 176.4 0.0 1.1e-51 175.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK61104.1 - 1.8e-44 152.4 0.0 3e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK61104.1 - 5.6e-18 64.8 0.0 1.6e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_28 PF00295.17 KIK61105.1 - 1.3e-60 205.2 18.4 1.7e-60 204.8 18.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1565 PF07602.11 KIK61105.1 - 1.2e-05 24.8 19.7 0.00015 21.2 19.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) NosD PF05048.13 KIK61105.1 - 0.004 16.5 12.2 0.0077 15.5 12.0 1.7 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) MUG113 PF13455.6 KIK61106.1 - 2.5e-15 56.9 0.0 7.3e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK61106.1 - 3.1e-09 37.3 0.0 4.7e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 T5orf172 domain Glyco_hydro_11 PF00457.17 KIK61107.1 - 8.5e-68 227.5 4.6 9.8e-68 227.3 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MUG113 PF13455.6 KIK61108.1 - 1.4e-14 54.5 0.0 3.3e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK61108.1 - 2.9e-11 43.8 0.0 3.1e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain WRC PF08879.10 KIK61108.1 - 0.049 13.3 0.7 0.12 12.1 0.7 1.6 1 0 0 1 1 1 0 WRC T5orf172 PF10544.9 KIK61110.1 - 3.5e-09 37.1 0.1 9e-07 29.4 0.0 3.2 3 0 0 3 3 3 2 T5orf172 domain MUG113 PF13455.6 KIK61110.1 - 4.8e-08 33.6 0.1 2.3e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 CUE PF02845.16 KIK61111.1 - 5.1e-12 45.3 0.0 8.5e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain SpoVAD PF07451.11 KIK61111.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Cue1_U7BR PF18499.1 KIK61111.1 - 0.11 12.5 0.9 0.24 11.4 0.8 1.5 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Pro-kuma_activ PF09286.11 KIK61113.1 - 1.2e-46 158.6 0.0 1.9e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK61113.1 - 0.00064 19.1 2.1 0.0013 18.1 2.1 1.4 1 0 0 1 1 1 1 Subtilase family Annexin PF00191.20 KIK61115.1 - 5.2e-07 29.6 0.5 1.7e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Annexin Annexin PF00191.20 KIK61116.1 - 8.9e-15 54.5 0.0 1.3e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Annexin Pro-kuma_activ PF09286.11 KIK61117.1 - 1.7e-42 145.1 0.2 3e-42 144.3 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK61117.1 - 6.6e-07 28.9 2.0 1.2e-06 28.1 2.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF2145 PF09916.9 KIK61117.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Glyco_hydro_28 PF00295.17 KIK61120.1 - 3e-64 217.1 16.1 3.5e-64 216.9 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1565 PF07602.11 KIK61120.1 - 3.6e-07 29.8 17.5 4.4e-07 29.5 14.6 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) NosD PF05048.13 KIK61120.1 - 0.035 13.4 18.1 0.12 11.6 18.1 2.1 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) ID PF18543.1 KIK61120.1 - 0.059 13.4 2.3 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Intracellular delivery domain SWM_repeat PF13753.6 KIK61120.1 - 9.8 6.4 7.7 48 4.2 0.7 3.6 2 1 1 3 3 3 0 Putative flagellar system-associated repeat Phage_TAC_2 PF06894.11 KIK61122.1 - 0.06 13.1 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Cyclase PF04199.13 KIK61127.1 - 1.9e-27 96.2 0.0 2.3e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase ATG16 PF08614.11 KIK61128.1 - 1.6e-05 25.2 4.6 1.6e-05 25.2 4.6 3.4 3 0 0 3 3 2 2 Autophagy protein 16 (ATG16) COG2 PF06148.11 KIK61128.1 - 0.0039 17.3 2.5 0.0039 17.3 2.5 2.5 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.6 KIK61128.1 - 0.019 15.4 3.8 7.6 7.0 0.0 3.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Rab3-GTPase_cat PF13890.6 KIK61128.1 - 0.1 12.2 1.3 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit LIF_OSM PF01291.17 KIK61128.1 - 0.19 11.9 3.8 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 LIF / OSM family DUF1664 PF07889.12 KIK61128.1 - 0.2 11.7 5.8 0.24 11.4 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 KIK61128.1 - 0.53 9.2 9.8 0.046 12.7 2.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Mod_r PF07200.13 KIK61128.1 - 1.1 9.4 18.1 0.94 9.6 5.8 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Laminin_II PF06009.12 KIK61128.1 - 3.9 7.5 9.0 0.42 10.6 3.9 2.0 2 0 0 2 2 2 0 Laminin Domain II Macoilin PF09726.9 KIK61128.1 - 3.9 5.9 14.9 0.019 13.6 3.7 2.5 2 1 0 2 2 2 0 Macoilin family CENP-F_leu_zip PF10473.9 KIK61128.1 - 4 7.4 27.4 0.099 12.7 10.7 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIK61128.1 - 4.8 6.0 19.1 0.37 9.6 7.5 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KIK61128.1 - 7.8 6.3 21.7 10 5.9 1.0 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KIK61128.1 - 8.9 6.7 17.3 66 3.9 17.3 2.2 1 1 0 1 1 1 0 Fez1 HNH_2 PF13391.6 KIK61130.1 - 8.7e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease APH PF01636.23 KIK61131.1 - 3.2e-05 24.0 0.2 8.4e-05 22.6 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family HNH_2 PF13391.6 KIK61132.1 - 0.0074 16.4 0.1 0.022 14.9 0.1 2.0 1 1 0 1 1 1 1 HNH endonuclease RSN1_7TM PF02714.15 KIK61133.1 - 6.5e-61 206.0 30.0 1.3e-33 116.5 12.5 2.6 2 1 1 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIK61133.1 - 2.7e-39 135.2 0.0 4.2e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK61133.1 - 3e-34 118.0 0.2 3e-34 118.0 0.2 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Sulfate_transp PF00916.20 KIK61134.1 - 5.8e-87 291.9 13.4 5.8e-87 291.9 13.4 1.6 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 KIK61134.1 - 7.9e-15 54.5 0.0 1.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIK61134.1 - 0.0034 17.7 0.0 0.0079 16.5 0.0 1.7 1 0 0 1 1 1 1 STAS domain XPG_N PF00752.17 KIK61136.1 - 0.0033 17.9 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain BUD22 PF09073.10 KIK61136.1 - 1.8 7.8 11.6 0.82 8.9 8.4 1.9 2 0 0 2 2 2 0 BUD22 eIF-3c_N PF05470.12 KIK61136.1 - 5.1 5.3 8.3 8.5 4.5 8.3 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BcrAD_BadFG PF01869.20 KIK61137.1 - 4.7e-10 39.4 0.0 2.6e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KIK61137.1 - 0.24 10.9 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Cornichon PF03311.14 KIK61138.1 - 1.2e-52 177.4 10.7 1.4e-52 177.2 10.7 1.0 1 0 0 1 1 1 1 Cornichon protein Pombe_5TM PF09437.10 KIK61140.1 - 0.047 13.3 3.4 0.063 12.9 3.4 1.1 1 0 0 1 1 1 0 Pombe specific 5TM protein Methyltransf_2 PF00891.18 KIK61141.1 - 5.3e-19 68.4 0.0 3.2e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KIK61141.1 - 0.00013 22.6 0.0 0.00055 20.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK61141.1 - 0.0012 19.5 0.0 0.0094 16.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61141.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF1264 PF06884.11 KIK61141.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) MTS PF05175.14 KIK61141.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIK61141.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KIK61141.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase AMP-binding PF00501.28 KIK61143.1 - 2.1e-88 296.8 0.0 2.7e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK61143.1 - 1e-12 48.8 0.8 1.9e-12 47.9 0.8 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIK61144.1 - 1.2e-80 271.2 0.0 1.3e-66 225.0 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KIK61144.1 - 9.3e-15 55.4 0.2 3.3e-14 53.6 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 KIK61145.1 - 4.2e-09 36.1 0.0 6.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK61145.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KIK61145.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_1_2 PF00155.21 KIK61149.1 - 3.6e-37 128.4 0.0 4.9e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 KIK61149.1 - 0.002 16.8 0.0 0.0028 16.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Cys_Met_Meta_PP PF01053.20 KIK61149.1 - 0.093 11.2 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.25 KIK61150.1 - 6.2e-39 133.5 0.0 7.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK61150.1 - 1.4e-29 103.3 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK61150.1 - 2.9e-09 37.1 0.1 4.1e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK61150.1 - 0.092 12.2 0.4 0.74 9.2 0.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MerT PF02411.15 KIK61155.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 MerT mercuric transport protein BTB PF00651.31 KIK61157.1 - 0.00016 21.9 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIK61158.1 - 9.5e-05 22.6 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_17 PF04724.13 KIK61160.1 - 2.3e-136 454.5 0.0 2.7e-136 454.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 zf-MYND PF01753.18 KIK61161.1 - 8.5e-09 35.4 13.7 2.4e-08 33.9 13.7 1.8 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 KIK61161.1 - 0.033 13.7 3.2 0.061 12.8 3.2 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-Mss51 PF13824.6 KIK61161.1 - 1.3 9.1 6.0 3.3 7.9 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KIK61161.1 - 6.5 7.2 10.3 14 6.1 10.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ATP19 PF11022.8 KIK61162.1 - 2.7 8.4 4.5 1.5 9.3 1.8 2.1 1 1 1 2 2 2 0 ATP synthase subunit K Nairo_nucleo PF02477.15 KIK61163.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein Evr1_Alr PF04777.13 KIK61164.1 - 2.5e-28 98.5 0.2 3.3e-28 98.1 0.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Abhydrolase_1 PF00561.20 KIK61165.1 - 3.1e-10 40.1 0.0 2.1e-09 37.4 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK61165.1 - 7.5e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PALP PF00291.25 KIK61169.1 - 2.6e-36 125.6 0.2 3.1e-36 125.3 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Dyp_perox PF04261.12 KIK61171.1 - 1.4e-10 40.7 0.0 1.3e-09 37.6 0.0 2.3 2 1 0 2 2 2 1 Dyp-type peroxidase family Dyp_perox PF04261.12 KIK61172.1 - 5.3e-09 35.5 0.0 1.6e-07 30.6 0.0 2.8 2 1 0 2 2 2 1 Dyp-type peroxidase family F-box-like PF12937.7 KIK61173.1 - 1.3e-07 31.4 2.9 2.5e-07 30.5 0.8 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK61173.1 - 0.0005 19.9 0.7 0.037 13.9 0.1 2.9 2 0 0 2 2 2 2 F-box domain DUF5588 PF17826.1 KIK61174.1 - 0.58 9.0 2.7 0.82 8.5 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5588) MAP65_ASE1 PF03999.12 KIK61176.1 - 0.012 14.3 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MCC-bdg_PDZ PF10506.9 KIK61179.1 - 0.06 13.4 0.6 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PUA PF01472.20 KIK61179.1 - 0.11 12.5 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 PUA domain Miga PF10265.9 KIK61180.1 - 0.045 12.7 0.7 0.055 12.4 0.7 1.0 1 0 0 1 1 1 0 Mitoguardin ketoacyl-synt PF00109.26 KIK61181.1 - 6.3e-53 179.9 0.6 2.1e-52 178.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK61181.1 - 7.6e-40 137.3 0.0 1.4e-39 136.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIK61181.1 - 5.1e-33 114.5 0.0 9.9e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KIK61181.1 - 6e-31 106.9 0.0 1.1e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIK61181.1 - 3.6e-30 105.2 0.0 1.1e-29 103.6 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 KIK61181.1 - 5.6e-20 71.5 0.2 1.7e-06 28.3 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KIK61181.1 - 5.6e-14 52.7 0.0 5.7e-13 49.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KIK61181.1 - 4.7e-13 49.6 0.0 1.2e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KIK61181.1 - 7.2e-11 42.2 0.0 2.1e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61181.1 - 2.3e-09 37.2 0.0 9.8e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61181.1 - 1.2e-08 35.5 0.0 1.2e-07 32.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61181.1 - 2.4e-08 34.6 0.0 2e-06 28.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Thioesterase PF00975.20 KIK61181.1 - 1.6e-05 25.1 0.0 0.00022 21.4 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain ACP_syn_III PF08545.10 KIK61181.1 - 0.00016 21.4 0.1 0.00061 19.6 0.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.18 KIK61181.1 - 0.0038 16.6 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KIK61181.1 - 0.0051 16.5 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase adh_short PF00106.25 KIK61181.1 - 0.0076 15.7 1.5 0.035 13.6 0.2 2.6 2 1 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KIK61181.1 - 0.052 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KIK61182.1 - 6.7e-14 53.0 0.0 9.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF478 PF04334.12 KIK61183.1 - 0.45 10.6 2.7 0.43 10.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF478) AMP-binding PF00501.28 KIK61184.1 - 7.7e-79 265.3 0.0 9.3e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK61184.1 - 8.5e-13 49.1 0.0 1.9e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIK61185.1 - 4.9e-29 101.2 0.1 4e-28 98.2 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK61185.1 - 3.3e-18 65.8 0.0 8.9e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KIK61185.1 - 3.1e-05 24.3 0.0 7.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIK61185.1 - 0.13 11.7 0.0 0.55 9.6 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RVT_3 PF13456.6 KIK61188.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_thumb PF06817.14 KIK61189.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase thumb domain NAD_binding_4 PF07993.12 KIK61193.1 - 3.2e-09 36.4 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KIK61193.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KIK61193.1 - 0.051 13.0 0.0 0.093 12.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TauD PF02668.16 KIK61194.1 - 7.1e-34 117.8 0.0 1.1e-33 117.2 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KIK61195.1 - 8.7e-15 54.5 37.5 8.7e-15 54.5 37.5 1.8 1 1 2 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK61195.1 - 3.7e-10 39.7 5.9 3.7e-10 39.7 5.9 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KIK61195.1 - 4.5e-05 22.5 11.8 4.5e-05 22.5 11.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TPIP1 PF15338.6 KIK61195.1 - 0.076 13.1 1.1 0.16 12.1 0.2 1.9 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 DUF4097 PF13349.6 KIK61197.1 - 0.00015 21.2 5.4 0.0011 18.3 3.5 2.6 2 1 0 3 3 3 1 Putative adhesin Phage_Gp19 PF09355.10 KIK61197.1 - 0.016 15.6 0.6 0.22 12.0 0.6 2.6 1 1 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 PH PF00169.29 KIK61198.1 - 1.6e-05 25.3 0.0 6.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 PH domain Peroxidase_2 PF01328.17 KIK61199.1 - 1.5e-46 159.3 0.0 2e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 KIK61200.1 - 1.6e-45 156.0 0.0 2.1e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Caleosin PF05042.13 KIK61200.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Caleosin related protein Peroxidase_2 PF01328.17 KIK61201.1 - 1.9e-48 165.5 0.0 2.4e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 KIK61202.1 - 3.2e-50 171.2 0.0 4.2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 LCAT PF02450.15 KIK61203.1 - 4.2e-78 263.2 1.2 3.5e-71 240.4 0.4 2.3 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase PspB PF06667.12 KIK61204.1 - 0.019 15.0 0.1 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Phage shock protein B AIM5 PF17050.5 KIK61205.1 - 6.4e-05 23.7 0.0 8.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DOG1 PF14144.6 KIK61205.1 - 0.025 14.8 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 Seed dormancy control Trp_halogenase PF04820.14 KIK61206.1 - 2.5e-31 109.0 0.0 1.7e-14 53.5 0.0 2.8 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK61206.1 - 4.8e-14 52.4 0.0 1.8e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK61206.1 - 7.2e-07 29.3 0.2 6.6e-06 26.3 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK61206.1 - 1e-05 25.3 0.1 0.0071 16.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK61206.1 - 0.00015 20.7 0.0 0.00038 19.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KIK61206.1 - 0.00015 22.2 0.0 0.0061 17.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK61206.1 - 0.00019 20.8 0.1 0.00037 19.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK61206.1 - 0.003 16.7 0.0 0.0059 15.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK61206.1 - 0.0033 16.8 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK61206.1 - 0.009 15.3 0.2 0.045 13.0 0.1 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK61206.1 - 0.011 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KIK61206.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KIK61206.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK61206.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KIK61206.1 - 0.11 11.5 0.0 0.27 10.2 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KIK61207.1 - 6.9e-22 77.9 1.4 3.4e-12 46.0 0.0 3.0 2 2 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK61207.1 - 2.6e-13 49.9 0.0 1.1e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK61207.1 - 9e-05 22.6 0.2 0.00031 20.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK61207.1 - 0.00041 19.2 0.2 0.0006 18.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIK61207.1 - 0.0005 19.3 0.2 0.00081 18.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK61207.1 - 0.00057 19.4 0.4 0.001 18.5 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK61207.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK61207.1 - 0.0014 18.3 0.3 0.0069 16.0 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK61207.1 - 0.0026 17.1 0.1 0.0047 16.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KIK61207.1 - 0.0098 15.0 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KIK61207.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIK61207.1 - 0.048 12.9 0.3 0.093 12.0 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KIK61208.1 - 2.9e-46 158.0 0.0 1.6e-45 155.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family LNS2 PF08235.13 KIK61208.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Aldo_ket_red PF00248.21 KIK61209.1 - 2.5e-47 161.5 0.0 2.3e-46 158.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Solute_trans_a PF03619.16 KIK61210.1 - 2.1e-84 283.2 13.6 2.6e-84 282.9 13.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 KIK61210.1 - 0.027 14.7 0.8 0.027 14.7 0.8 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Fer4_9 PF13187.6 KIK61211.1 - 3.9 7.7 8.8 0.4 10.9 2.7 2.2 2 1 1 3 3 2 0 4Fe-4S dicluster domain Myb_DNA-bind_2 PF08914.11 KIK61216.1 - 1.1e-12 47.9 12.2 8.1e-06 25.9 1.9 3.5 3 0 0 3 3 3 3 Rap1 Myb domain Myb_DNA-binding PF00249.31 KIK61216.1 - 0.00081 19.5 0.0 14 6.0 0.1 3.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF3342 PF11822.8 KIK61216.1 - 0.04 14.1 0.1 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) YcaO PF02624.16 KIK61216.1 - 0.05 12.9 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Mcm10 PF09332.11 KIK61216.1 - 0.078 12.4 3.1 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Mcm10 replication factor Myb_DNA-bind_5 PF13873.6 KIK61216.1 - 2 8.5 6.3 8.7 6.5 0.0 4.1 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain p450 PF00067.22 KIK61217.1 - 7.8e-11 41.4 0.0 9e-11 41.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK61218.1 - 3.6e-47 161.2 0.0 4.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF325 PF03804.13 KIK61218.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.7 2 0 0 2 2 2 0 Viral proteins of unknown function CdiI_2 PF18593.1 KIK61218.1 - 0.071 13.8 0.3 1.4 9.6 0.0 2.3 2 0 0 2 2 2 0 CdiI immunity protein tRNA-synt_2 PF00152.20 KIK61222.1 - 3.2e-85 286.0 0.0 5e-85 285.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK61222.1 - 5.5e-12 45.5 0.1 1.3e-11 44.3 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Casc1_N PF15927.5 KIK61222.1 - 0.0031 17.2 5.7 0.0073 16.0 5.3 1.7 1 1 1 2 2 2 1 Cancer susceptibility candidate 1 N-terminus tRNA_anti_2 PF13742.6 KIK61222.1 - 0.0064 16.7 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HIN PF02760.15 KIK61222.1 - 0.019 14.7 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain Ins134_P3_kin PF05770.11 KIK61222.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain DUF1204 PF06721.11 KIK61222.1 - 0.054 12.9 6.0 0.085 12.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) OspE PF02471.17 KIK61222.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Borrelia outer surface protein E F-box-like PF12937.7 KIK61223.1 - 5.7e-07 29.3 1.4 1.5e-06 28.0 1.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK61223.1 - 0.0018 18.1 0.3 0.0071 16.2 0.3 2.2 1 0 0 1 1 1 1 F-box domain Orthopox_A5L PF06193.11 KIK61224.1 - 0.048 13.1 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like CxC4 PF18717.1 KIK61225.1 - 2.9e-44 150.1 0.0 8e-44 148.7 0.0 1.8 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK61225.1 - 5.9e-05 22.8 1.2 0.0001 22.0 1.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4687 PF15747.5 KIK61226.1 - 3.7 8.0 12.7 4.2 7.9 8.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) LPD13 PF18825.1 KIK61227.1 - 0.057 13.2 0.2 0.081 12.7 0.2 1.5 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 13 DivIC PF04977.15 KIK61227.1 - 0.42 10.4 3.2 0.62 9.9 3.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Rep_fac-A_3 PF08661.11 KIK61228.1 - 2.9e-06 27.6 0.1 4.4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Ribosomal_L13e PF01294.18 KIK61229.1 - 0.016 15.1 0.3 0.024 14.5 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L13e HALZ PF02183.18 KIK61229.1 - 0.018 15.3 4.2 0.2 11.9 0.4 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KIK61229.1 - 0.038 14.1 9.8 5.7 7.1 0.6 3.3 2 1 1 3 3 3 0 bZIP transcription factor RNA_helicase PF00910.22 KIK61229.1 - 0.061 13.7 0.1 0.13 12.7 0.1 1.5 1 1 0 1 1 1 0 RNA helicase DUF4446 PF14584.6 KIK61229.1 - 0.073 13.1 0.7 0.13 12.2 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DivIC PF04977.15 KIK61229.1 - 0.3 10.9 3.6 0.28 11.0 0.3 2.5 1 1 2 3 3 3 0 Septum formation initiator YabA PF06156.13 KIK61229.1 - 0.52 11.0 8.8 1.7 9.3 0.9 2.7 1 1 1 2 2 2 0 Initiation control protein YabA F-box-like PF12937.7 KIK61231.1 - 0.00091 19.1 0.1 0.0024 17.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like HTH_23 PF13384.6 KIK61233.1 - 2.1e-07 30.6 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KIK61233.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KIK61233.1 - 0.00019 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 KIK61233.1 - 0.00024 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.20 KIK61233.1 - 0.0042 17.4 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Transposase PAX PF00292.18 KIK61233.1 - 0.0089 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KIK61233.1 - 0.017 15.7 0.0 0.28 11.8 0.0 2.3 1 1 1 2 2 2 0 Homeodomain-like domain DUF2802 PF10975.8 KIK61233.1 - 0.02 15.0 0.1 0.049 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) GerE PF00196.19 KIK61233.1 - 0.087 12.4 0.2 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 KIK61233.1 - 0.089 12.9 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MerR_1 PF13411.6 KIK61233.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 MerR HTH family regulatory protein HTH_38 PF13936.6 KIK61233.1 - 0.22 11.3 0.1 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PapA_C PF16911.5 KIK61234.1 - 0.063 13.3 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus zf-CCHC_4 PF14392.6 KIK61234.1 - 0.36 10.6 4.2 0.61 9.9 4.2 1.3 1 0 0 1 1 1 0 Zinc knuckle GIT_CC PF16559.5 KIK61235.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RVT_2 PF07727.14 KIK61235.1 - 0.055 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2749 PF10907.8 KIK61237.1 - 0.084 13.0 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Hydrolase_4 PF12146.8 KIK61239.1 - 7.6e-54 182.5 0.0 1.1e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK61239.1 - 9e-14 52.6 0.0 1.2e-13 52.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK61239.1 - 3.9e-10 39.8 0.0 6.6e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK61239.1 - 1.2e-05 24.9 0.2 0.041 13.4 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KIK61239.1 - 0.00026 20.6 0.0 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF900 PF05990.12 KIK61239.1 - 0.00095 18.7 0.2 0.0058 16.2 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 KIK61239.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KIK61239.1 - 0.024 14.4 0.2 0.43 10.4 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase RMMBL PF07521.12 KIK61239.1 - 0.042 13.8 0.1 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Esterase_phd PF10503.9 KIK61239.1 - 0.07 12.6 0.0 9.2 5.7 0.0 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase PGAP1 PF07819.13 KIK61239.1 - 0.083 12.6 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein DUF1749 PF08538.10 KIK61239.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) FSH1 PF03959.13 KIK61239.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.11 KIK61239.1 - 0.19 11.1 0.0 0.95 8.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGP_phosphatase PF09419.10 KIK61240.1 - 1.4e-41 141.9 0.0 2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KIK61240.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like PGP_phosphatase PF09419.10 KIK61241.1 - 3.9e-07 29.9 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase FAD_oxidored PF12831.7 KIK61241.1 - 0.0005 19.5 0.0 0.0022 17.4 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK61241.1 - 0.0016 17.4 0.0 0.042 12.7 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase Hydrolase_like PF13242.6 KIK61241.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Pyr_redox_2 PF07992.14 KIK61241.1 - 0.18 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK61242.1 - 0.00024 20.6 0.0 0.00066 19.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK61242.1 - 0.085 11.7 0.0 0.74 8.6 0.0 2.3 2 1 1 3 3 3 0 Tryptophan halogenase OPT PF03169.15 KIK61243.1 - 6.4e-180 599.8 42.6 7.7e-180 599.6 42.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.9 KIK61243.1 - 0.53 9.0 11.3 1.5 7.5 4.0 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) KinB_sensor PF16767.5 KIK61244.1 - 0.066 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Trp_halogenase PF04820.14 KIK61246.1 - 0.012 14.5 0.0 0.79 8.5 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.7 KIK61246.1 - 0.13 11.5 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 KIK61247.1 - 0.0068 17.0 0.1 0.0083 16.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KIK61247.1 - 0.028 13.1 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 KIK61247.1 - 0.048 13.3 0.0 0.071 12.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold ABC_membrane PF00664.23 KIK61248.1 - 1.3e-52 179.2 2.5 1.7e-52 178.7 2.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIK61248.1 - 1.4e-30 106.6 0.0 3.5e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK61248.1 - 5.1e-05 22.8 1.3 0.011 15.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK61248.1 - 0.015 15.7 1.3 0.062 13.7 0.5 2.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KIK61248.1 - 0.025 13.9 0.1 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KIK61248.1 - 0.035 14.2 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 KIK61248.1 - 0.06 13.1 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK61248.1 - 0.077 12.8 0.2 14 5.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system GerPC PF10737.9 KIK61249.1 - 0.011 15.8 6.2 0.02 14.9 6.2 1.5 1 0 0 1 1 1 0 Spore germination protein GerPC DUF826 PF05696.11 KIK61249.1 - 0.03 14.4 3.7 0.12 12.5 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Golgin_A5 PF09787.9 KIK61249.1 - 0.03 13.8 11.7 0.047 13.2 11.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 BEN PF10523.9 KIK61249.1 - 0.03 14.5 0.4 0.061 13.6 0.4 1.5 1 0 0 1 1 1 0 BEN domain Asp-B-Hydro_N PF05279.11 KIK61249.1 - 0.035 14.2 2.9 0.048 13.7 2.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1515 PF07439.11 KIK61249.1 - 0.041 13.9 3.4 4.8 7.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Plasmid_RAQPRD PF09686.10 KIK61249.1 - 0.056 13.7 0.1 0.056 13.7 0.1 3.3 3 1 1 4 4 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Herpes_UL92 PF03048.14 KIK61249.1 - 0.068 13.0 0.7 0.11 12.3 0.7 1.3 1 0 0 1 1 1 0 UL92 family HI0933_like PF03486.14 KIK61249.1 - 0.17 10.5 2.5 0.24 10.0 2.5 1.2 1 0 0 1 1 1 0 HI0933-like protein PrmC_N PF17827.1 KIK61249.1 - 0.17 12.5 1.2 0.55 10.9 0.4 2.1 2 0 0 2 2 2 0 PrmC N-terminal domain LCIB_C_CA PF18599.1 KIK61249.1 - 0.39 10.0 4.3 4.5 6.5 1.4 2.9 1 1 2 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF445 PF04286.12 KIK61249.1 - 0.51 10.1 7.8 1 9.1 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) HIP1_clath_bdg PF16515.5 KIK61249.1 - 1 10.0 11.8 5.9 7.6 9.3 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YgaB PF14182.6 KIK61249.1 - 1.8 9.0 13.3 9.1 6.8 0.3 3.4 1 1 2 3 3 3 0 YgaB-like protein Fib_alpha PF08702.10 KIK61249.1 - 2.1 8.5 12.6 2.4 8.3 8.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PRP1_N PF06424.12 KIK61249.1 - 3.6 8.0 6.6 6.3 7.2 6.1 1.5 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal TMPIT PF07851.13 KIK61249.1 - 4 6.6 6.3 6.9 5.8 6.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein YojJ PF10372.9 KIK61249.1 - 9.6 6.4 11.4 1.1 9.4 0.9 3.5 2 2 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Sde2_N_Ubi PF13019.6 KIK61251.1 - 3.7e-52 176.5 0.2 3.7e-52 176.5 0.2 1.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain SnoaL_2 PF12680.7 KIK61252.1 - 7.3e-09 36.2 0.0 8.2e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KIK61252.1 - 2.4e-06 27.7 0.0 2.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIK61252.1 - 0.013 15.9 0.0 0.015 15.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL PF07366.12 KIK61252.1 - 0.044 13.6 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Amino_oxidase PF01593.24 KIK61253.1 - 6.9e-47 160.8 0.0 1e-46 160.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK61253.1 - 2.7e-13 49.9 0.1 5.5e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK61253.1 - 1.1e-06 28.1 0.4 5e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK61253.1 - 9.7e-06 26.1 0.7 7.7e-05 23.2 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK61253.1 - 1.3e-05 25.0 4.2 5.4e-05 22.9 2.8 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK61253.1 - 0.00018 21.5 1.4 0.078 13.0 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KIK61253.1 - 0.00064 19.0 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KIK61253.1 - 0.0018 17.1 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KIK61253.1 - 0.0018 17.6 0.1 0.0029 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KIK61253.1 - 0.012 15.5 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK61253.1 - 0.019 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KIK61253.1 - 0.023 13.8 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KIK61253.1 - 0.031 13.6 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FMO-like PF00743.19 KIK61253.1 - 0.19 10.1 0.2 0.3 9.5 0.2 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Ank_5 PF13857.6 KIK61254.1 - 1.3e-15 57.3 0.3 3.9e-08 33.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK61254.1 - 4.7e-12 46.2 2.3 2.7e-06 27.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK61254.1 - 1.2e-10 41.8 0.2 3.4e-10 40.4 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK61254.1 - 2.4e-08 33.6 0.1 0.001 19.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIK61254.1 - 6.2e-08 32.7 0.8 0.00011 22.4 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Helo_like_N PF17111.5 KIK61254.1 - 3.1e-05 23.4 1.2 6.1e-05 22.5 1.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NUDIX PF00293.28 KIK61255.1 - 5.4e-15 55.6 0.0 9.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIK61255.1 - 1.1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIK61255.1 - 0.0014 18.2 2.0 0.0026 17.4 2.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain A2M PF00207.22 KIK61256.1 - 0.0053 16.6 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Fibrinogen_aC PF12160.8 KIK61256.1 - 0.061 13.2 0.4 0.22 11.4 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha C domain DUF3112 PF11309.8 KIK61257.1 - 0.23 10.9 2.5 0.58 9.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) PBP1_TM PF14812.6 KIK61257.1 - 0.69 10.3 13.8 0.69 10.3 2.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ubiquitin PF00240.23 KIK61258.1 - 7e-07 28.9 0.4 3.8e-06 26.6 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIK61258.1 - 7.4e-06 26.3 0.2 3.1e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain PI3K_rbd PF00794.18 KIK61258.1 - 0.0046 17.1 0.0 0.0057 16.8 0.0 1.1 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain RAWUL PF16207.5 KIK61258.1 - 0.0064 17.1 0.0 0.0076 16.9 0.0 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 KIK61258.1 - 0.018 14.8 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4431 PF14485.6 KIK61258.1 - 0.025 14.4 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) UN_NPL4 PF11543.8 KIK61258.1 - 0.069 13.6 0.0 0.082 13.4 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CFEM PF05730.11 KIK61259.1 - 1.1e-10 41.4 14.1 2e-10 40.6 14.1 1.4 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 KIK61259.1 - 1.3 7.5 6.6 1.3 7.4 6.6 1.1 1 0 0 1 1 1 0 Macoilin family TP_methylase PF00590.20 KIK61261.1 - 2.2e-23 83.3 0.0 4.7e-23 82.3 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases RNA_pol_inhib PF16857.5 KIK61261.1 - 0.027 14.2 0.3 0.062 13.1 0.3 1.6 1 0 0 1 1 1 0 RNA polymerase inhibitor CE2_N PF17996.1 KIK61262.1 - 0.011 15.7 0.1 0.89 9.6 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Gly-zipper_Omp PF13488.6 KIK61262.1 - 0.025 14.5 0.3 0.066 13.2 0.2 1.7 2 0 0 2 2 2 0 Glycine zipper DUF4064 PF13273.6 KIK61262.1 - 0.044 14.1 0.1 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Rick_17kDa_Anti PF05433.15 KIK61262.1 - 0.051 13.4 0.2 0.051 13.4 0.2 1.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ntox30 PF15532.6 KIK61262.1 - 0.14 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 30 Orf78 PF06024.12 KIK61262.1 - 0.2 12.0 0.0 0.53 10.6 0.0 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Glycophorin_A PF01102.18 KIK61263.1 - 0.0036 17.5 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A CE2_N PF17996.1 KIK61263.1 - 0.0053 16.7 0.7 0.25 11.3 0.1 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Ank_4 PF13637.6 KIK61264.1 - 4.7e-53 176.9 9.4 2.3e-10 40.8 0.0 6.2 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK61264.1 - 6.6e-49 164.4 7.4 2.7e-16 59.9 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK61264.1 - 3.4e-39 128.3 4.1 0.00033 20.9 0.0 8.6 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KIK61264.1 - 7.8e-33 112.1 3.0 3.5e-08 33.6 0.1 7.6 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KIK61264.1 - 9.2e-32 108.1 9.8 0.00093 19.5 0.0 8.2 7 1 1 8 8 8 7 Ankyrin repeat NACHT PF05729.12 KIK61265.1 - 2e-12 47.3 0.0 4e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK61265.1 - 0.00012 22.3 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK61265.1 - 0.00088 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KIK61265.1 - 0.0018 17.6 0.3 0.33 10.1 0.1 2.1 1 1 1 2 2 2 2 KAP family P-loop domain NB-ARC PF00931.22 KIK61265.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain LuxQ-periplasm PF09308.10 KIK61265.1 - 0.016 14.7 0.2 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 LuxQ, periplasmic DEAD PF00270.29 KIK61265.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KIK61265.1 - 0.13 12.7 0.6 0.43 11.0 0.1 2.4 2 1 0 2 2 2 0 RNA helicase Sigma_reg_N PF13800.6 KIK61265.1 - 8.4 6.8 6.5 13 6.2 0.1 3.1 2 1 1 3 3 3 0 Sigma factor regulator N-terminal CE2_N PF17996.1 KIK61267.1 - 0.00015 21.7 0.5 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Protocadherin PF08374.11 KIK61267.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 KIK61267.1 - 0.022 15.6 0.0 0.041 14.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rick_17kDa_Anti PF05433.15 KIK61267.1 - 0.032 14.1 6.0 0.059 13.2 6.0 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain TMEM51 PF15345.6 KIK61267.1 - 0.038 13.8 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FAM176 PF14851.6 KIK61267.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Gly-zipper_Omp PF13488.6 KIK61267.1 - 0.22 11.6 7.9 0.45 10.5 7.9 1.4 1 0 0 1 1 1 0 Glycine zipper Shisa PF13908.6 KIK61267.1 - 0.36 11.0 2.0 0.75 10.0 0.5 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 KIK61267.1 - 0.39 10.5 4.6 0.74 9.6 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mfa1 PF17445.2 KIK61267.1 - 0.74 9.9 6.6 2.4 8.2 6.6 1.9 1 0 0 1 1 1 0 Mating factor A1 SdrD_B PF17210.3 KIK61267.1 - 0.88 9.8 4.0 0.75 10.0 1.2 2.2 2 0 0 2 2 2 0 SdrD B-like domain Gly-zipper_YMGG PF13441.6 KIK61267.1 - 1.4 8.7 8.2 0.5 10.2 5.5 1.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper Coiled PF05710.12 KIK61267.1 - 2.6 8.9 13.5 0.13 13.2 3.4 3.0 3 0 0 3 3 3 0 Coiled coil CE2_N PF17996.1 KIK61268.1 - 6.7e-05 22.8 0.2 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Adeno_E3_CR2 PF02439.15 KIK61268.1 - 0.017 14.9 0.2 0.031 14.1 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KIK61268.1 - 0.024 14.0 1.7 0.053 12.9 1.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PGF-CTERM PF18204.1 KIK61268.1 - 1.2 9.2 4.4 2.3 8.3 4.4 1.5 1 0 0 1 1 1 0 PGF-CTERM motif CE2_N PF17996.1 KIK61269.1 - 0.072 13.1 0.2 3.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal SUR7 PF06687.12 KIK61270.1 - 1e-11 44.9 12.2 1.3e-11 44.5 12.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family EIIC-GAT PF03611.14 KIK61270.1 - 0.66 9.0 15.0 0.0095 15.1 7.3 1.7 2 0 0 2 2 2 0 PTS system sugar-specific permease component DUF3742 PF12553.8 KIK61270.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3742) Glyco_hydro_12 PF01670.16 KIK61271.1 - 1.2e-39 136.5 14.0 1.5e-39 136.2 14.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PPV_E2_C PF00511.17 KIK61271.1 - 0.34 11.1 8.1 3 8.1 0.3 2.3 1 1 1 2 2 2 0 E2 (early) protein, C terminal TPR_11 PF13414.6 KIK61273.1 - 5.3e-05 22.8 0.0 5.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 KIK61273.1 - 0.001 19.0 0.3 0.0059 16.6 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK61273.1 - 0.0036 17.9 0.0 0.0043 17.7 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_21 PF09976.9 KIK61273.1 - 0.014 15.1 0.0 0.014 15.1 0.0 1.0 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 KIK61273.1 - 0.049 13.5 0.2 0.078 12.8 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK61273.1 - 0.098 12.7 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat zf-CSL PF05207.13 KIK61274.1 - 0.097 12.4 0.3 3.6 7.4 0.1 2.3 2 0 0 2 2 2 0 CSL zinc finger HSP70 PF00012.20 KIK61275.1 - 6.8e-256 850.2 19.7 2.1e-255 848.6 19.7 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK61275.1 - 1.5e-14 53.6 6.5 1.1e-12 47.4 0.9 2.9 3 0 0 3 3 3 2 MreB/Mbl protein LCM PF04072.14 KIK61276.1 - 6.4e-23 81.7 0.0 1.5e-22 80.5 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase CE2_N PF17996.1 KIK61277.1 - 9.7e-07 28.8 0.2 0.0043 17.0 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Ntox30 PF15532.6 KIK61277.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 30 CBM_35 PF16990.5 KIK61277.1 - 1.7 8.9 5.0 1.7 8.9 0.9 2.3 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) CE2_N PF17996.1 KIK61279.1 - 0.0053 16.7 0.0 2.4 8.2 0.0 2.6 2 1 1 3 3 3 2 Carbohydrate esterase 2 N-terminal DUF5554 PF17709.1 KIK61282.1 - 0.03 14.4 0.0 0.038 14.1 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5554) CE2_N PF17996.1 KIK61283.1 - 3e-05 24.0 0.4 0.073 13.1 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Cript PF10235.9 KIK61284.1 - 0.034 14.7 0.1 0.049 14.2 0.1 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Glyco_transf_22 PF03901.17 KIK61287.1 - 5e-24 85.3 7.8 3e-22 79.4 2.2 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family FAD_binding_4 PF01565.23 KIK61288.1 - 1.5e-05 24.8 1.4 1.8e-05 24.5 1.4 1.1 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK61289.1 - 2e-08 34.2 0.1 3.9e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Catalase PF00199.19 KIK61290.1 - 5.4e-170 565.6 0.0 6.9e-170 565.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK61290.1 - 9.5e-17 61.0 0.1 2.2e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KIK61290.1 - 3.1e-13 49.6 0.1 5.8e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KIK61290.1 - 7.5e-09 35.6 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family FGGY_N PF00370.21 KIK61293.1 - 5.5e-66 222.6 0.2 8.5e-64 215.4 0.2 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIK61293.1 - 1.6e-60 204.3 1.1 1.6e-60 204.3 1.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain MIP PF00230.20 KIK61295.1 - 2.9e-47 161.3 8.7 3.5e-47 161.0 8.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Methyltransf_23 PF13489.6 KIK61296.1 - 1.6e-11 44.4 0.0 2.4e-11 43.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61296.1 - 3.8e-08 33.9 0.0 6.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61296.1 - 2e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61296.1 - 4.1e-05 23.4 0.0 5.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61296.1 - 0.0021 18.7 0.0 0.0038 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK61297.1 - 5.9e-15 55.5 0.0 8.3e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61297.1 - 3.1e-07 31.0 0.0 5.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61297.1 - 0.0026 17.1 0.0 0.0097 15.3 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK61297.1 - 0.019 15.6 0.0 0.036 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61297.1 - 0.042 13.6 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61298.1 - 2.7e-08 34.4 0.0 5.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK61298.1 - 5.8e-08 32.7 0.0 8.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61298.1 - 0.0017 17.8 0.0 0.004 16.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK61298.1 - 0.0033 18.1 0.0 0.0077 16.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61298.1 - 0.068 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MIP PF00230.20 KIK61299.1 - 1.5e-46 158.9 10.8 1.8e-46 158.7 10.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein GPI-anchored PF10342.9 KIK61301.1 - 1.3e-05 25.9 0.4 1.6e-05 25.5 0.4 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MoCF_biosynth PF00994.24 KIK61302.1 - 1.3e-31 109.1 0.0 3.3e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Probable molybdopterin binding domain Imp-YgjV PF10688.9 KIK61305.1 - 0.0049 16.7 8.6 0.078 12.8 0.8 2.8 2 1 1 3 3 3 2 Bacterial inner membrane protein TMEM210 PF15195.6 KIK61305.1 - 0.018 15.5 0.3 0.045 14.2 0.3 1.7 1 0 0 1 1 1 0 TMEM210 family DUF423 PF04241.15 KIK61307.1 - 4.2 7.6 7.2 0.83 9.9 0.2 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF423) TAL_FSA PF00923.19 KIK61309.1 - 2.2e-44 151.9 0.0 2.7e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GPI-anchored PF10342.9 KIK61310.1 - 1.3e-08 35.5 4.4 1.3e-08 35.5 4.4 2.2 1 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4690 PF15756.5 KIK61310.1 - 0.037 14.6 5.2 0.037 14.6 5.2 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Ank_2 PF12796.7 KIK61312.1 - 0.045 14.3 0.0 0.085 13.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK61312.1 - 0.081 13.3 0.0 0.63 10.4 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF5118 PF17162.4 KIK61313.1 - 0.0096 15.7 0.7 0.023 14.5 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5118) DUF2183 PF09949.9 KIK61315.1 - 6e-19 68.2 0.0 9.8e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KIK61315.1 - 0.11 11.9 0.0 9.3 5.6 0.0 2.6 3 0 0 3 3 3 0 LNS2 (Lipin/Ned1/Smp2) ATP-synt PF00231.19 KIK61317.1 - 2.2e-13 50.6 0.4 0.00018 21.3 0.0 3.0 1 1 1 2 2 2 2 ATP synthase Ank_4 PF13637.6 KIK61321.1 - 0.019 15.5 0.1 0.43 11.2 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK61321.1 - 0.034 14.5 0.1 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK61321.1 - 0.1 13.2 0.0 8.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KIK61322.1 - 2.8e-05 24.6 0.0 0.00012 22.6 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK61322.1 - 0.00011 22.5 0.1 1.2 9.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KIK61322.1 - 0.00011 22.7 0.2 0.087 13.4 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK61322.1 - 0.00033 20.9 1.9 0.57 10.9 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIK61322.1 - 0.047 14.0 0.1 0.41 11.0 0.1 2.3 1 1 0 1 1 1 0 Ankyrin repeats (many copies) DUF1658 PF07871.11 KIK61323.1 - 0.032 14.1 1.5 0.11 12.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1658) ATP-synt PF00231.19 KIK61325.1 - 0.0029 17.4 0.0 0.0029 17.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase Ank_2 PF12796.7 KIK61329.1 - 6.8e-28 97.1 1.1 5.1e-10 39.8 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK61329.1 - 1.6e-18 66.8 0.7 2.8e-11 43.7 0.0 3.3 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK61329.1 - 3e-16 59.2 0.3 1.3e-06 28.6 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK61329.1 - 1e-14 53.2 0.3 0.00058 20.1 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KIK61329.1 - 6e-09 36.0 1.2 0.0039 17.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat DUF1843 PF08898.10 KIK61329.1 - 0.02 15.4 0.9 0.91 10.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF2183 PF09949.9 KIK61330.1 - 0.00011 22.5 0.4 0.00016 22.0 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CybS PF05328.12 KIK61331.1 - 1.3e-41 141.4 0.1 1.6e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit CybS PF05328.12 KIK61332.1 - 2.8e-37 127.4 0.5 3.4e-37 127.1 0.5 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit CLN3 PF02487.17 KIK61333.1 - 9.5e-107 357.5 0.2 1.2e-106 357.2 0.2 1.1 1 0 0 1 1 1 1 CLN3 protein OTT_1508_deam PF14441.6 KIK61335.1 - 0.96 9.5 5.9 0.22 11.5 1.3 2.4 3 0 0 3 3 3 0 OTT_1508-like deaminase Fungal_trans PF04082.18 KIK61336.1 - 3.3e-18 65.7 0.0 8.3e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK61336.1 - 0.00036 20.6 14.9 0.00075 19.6 14.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pinin_SDK_memA PF04696.13 KIK61336.1 - 0.077 13.1 21.7 0.24 11.5 21.7 1.8 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Cupin_2 PF07883.11 KIK61337.1 - 1.8e-09 37.1 0.2 8.9e-09 34.9 0.1 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KIK61337.1 - 2.9e-05 23.7 0.1 6.5e-05 22.6 0.0 1.8 1 1 0 2 2 2 1 Cupin AraC_binding PF02311.19 KIK61337.1 - 0.0034 17.3 0.1 0.0049 16.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK61337.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EutQ PF06249.12 KIK61337.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cutinase PF01083.22 KIK61338.1 - 1.1e-46 159.0 0.2 1.3e-46 158.8 0.2 1.0 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KIK61338.1 - 0.01 15.4 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF563 PF04577.14 KIK61339.1 - 2.7e-16 60.3 0.0 1.9e-15 57.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF563) CemA PF03040.14 KIK61339.1 - 0.23 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 CemA family RRM_1 PF00076.22 KIK61341.1 - 4.9e-15 55.1 0.0 9e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK61341.1 - 0.026 14.6 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif RICTOR_phospho PF14665.6 KIK61341.1 - 1.2 9.5 5.4 1.1 9.6 3.3 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site DAO PF01266.24 KIK61343.1 - 2.9e-63 214.6 1.2 3.5e-63 214.3 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK61343.1 - 8.8e-06 25.2 0.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK61343.1 - 5.2e-05 22.5 0.2 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KIK61343.1 - 0.00045 20.2 0.4 0.019 14.9 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK61343.1 - 0.001 19.3 0.1 0.0024 18.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK61343.1 - 0.0013 17.8 0.0 0.58 9.2 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KIK61343.1 - 0.0019 17.6 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Sacchrp_dh_NADP PF03435.18 KIK61343.1 - 0.026 14.8 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KIK61343.1 - 0.06 13.9 0.0 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK61343.1 - 0.11 11.3 0.1 2 7.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK61343.1 - 0.12 11.6 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK61343.1 - 0.22 10.7 0.2 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SAP PF02037.27 KIK61345.1 - 0.00025 20.7 0.9 0.00025 20.7 0.9 2.0 2 0 0 2 2 2 1 SAP domain LETM1 PF07766.13 KIK61345.1 - 0.25 10.6 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 LETM1-like protein Pyr_redox_2 PF07992.14 KIK61346.1 - 2.8e-47 161.4 0.0 3.4e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK61346.1 - 3.2e-09 37.2 0.0 7.2e-08 32.9 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK61346.1 - 0.012 14.9 0.1 7 5.8 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WH1 PF00568.23 KIK61347.1 - 4.9e-06 26.5 0.1 8.7e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 WH1 domain PBD PF00786.28 KIK61347.1 - 0.0022 18.3 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KIK61349.1 - 1.7e-23 83.1 0.0 2.1e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Smg4_UPF3 PF03467.15 KIK61351.1 - 1e-54 185.2 0.9 1e-54 185.2 0.9 2.5 4 0 0 4 4 4 1 Smg-4/UPF3 family DUF4121 PF13497.6 KIK61351.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) DUF3915 PF13054.6 KIK61351.1 - 0.28 11.2 0.8 2.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SmAKAP PF15127.6 KIK61351.1 - 9.7 7.5 8.5 10 7.4 0.1 3.1 3 0 0 3 3 3 0 Small membrane A-kinase anchor protein Methyltransf_23 PF13489.6 KIK61352.1 - 2.2e-13 50.4 0.0 3e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61352.1 - 3.8e-09 37.1 0.0 6.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61352.1 - 8.2e-05 23.2 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61352.1 - 9.4e-05 21.9 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61352.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK61352.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SYF2 PF08231.12 KIK61354.1 - 1.5e-60 204.2 9.1 1.5e-60 204.2 9.1 1.9 2 1 0 2 2 2 1 SYF2 splicing factor Muted PF14942.6 KIK61354.1 - 0.94 9.8 14.3 0.5 10.7 9.3 2.3 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein ALS2CR8 PF15299.6 KIK61354.1 - 1.3 8.9 7.4 3 7.7 7.4 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 5_nucleotid PF05761.14 KIK61354.1 - 2.1 7.1 9.9 0.096 11.6 0.3 2.1 2 0 0 2 2 2 0 5' nucleotidase family Band_7_C PF16200.5 KIK61355.1 - 0.041 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of band_7 AT_hook PF02178.19 KIK61355.1 - 0.42 10.6 22.8 4.5 7.5 0.7 4.3 3 0 0 3 3 3 0 AT hook motif Adap_comp_sub PF00928.21 KIK61356.1 - 0.003 17.0 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF1450 PF07293.11 KIK61357.1 - 0.088 12.6 0.0 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1450) Adap_comp_sub PF00928.21 KIK61358.1 - 0.04 13.3 0.0 8.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Adaptor complexes medium subunit family EF-hand_1 PF00036.32 KIK61362.1 - 0.018 14.6 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KIK61362.1 - 0.03 14.8 0.4 0.047 14.1 0.4 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KIK61362.1 - 0.069 13.1 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain TPR_17 PF13431.6 KIK61364.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat DEAD PF00270.29 KIK61367.1 - 1.7e-20 73.5 0.0 6.3e-12 45.6 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK61367.1 - 2.6e-12 47.1 4.0 2.6e-09 37.4 0.0 3.1 3 1 1 4 4 4 2 Helicase conserved C-terminal domain Fungal_trans PF04082.18 KIK61368.1 - 1.5e-17 63.5 0.0 2.9e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK61368.1 - 0.00056 20.0 13.2 0.001 19.1 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2027 PF09640.10 KIK61368.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) FSH1 PF03959.13 KIK61369.1 - 2.1e-44 151.7 0.0 2.4e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIK61369.1 - 0.021 14.5 0.0 3.6 7.1 0.0 2.4 1 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK61369.1 - 0.1 11.9 0.0 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KIK61369.1 - 0.12 11.9 0.0 0.73 9.3 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.22 KIK61370.1 - 2.9e-46 157.7 0.1 3.3e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KIK61370.1 - 0.044 13.3 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Pam17 PF08566.10 KIK61370.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 VirJ PF06057.11 KIK61370.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Fungal_trans PF04082.18 KIK61371.1 - 0.00018 20.7 6.8 0.00042 19.4 6.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RBR PF17208.3 KIK61371.1 - 3.4 8.4 6.3 7.8 7.3 6.3 1.5 1 0 0 1 1 1 0 RNA binding Region DUF1687 PF07955.11 KIK61374.1 - 0.043 14.3 0.3 0.98 9.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) Whi5 PF08528.11 KIK61375.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Whi5 like Thaumatin PF00314.17 KIK61377.1 - 2.9e-72 242.8 12.0 3.3e-72 242.6 12.0 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK61377.1 - 0.0002 20.7 2.1 0.0003 20.2 0.1 1.9 2 0 0 2 2 2 1 Beta-1,3-glucanase Thaumatin PF00314.17 KIK61378.1 - 2.6e-68 229.9 6.5 2.8e-68 229.7 6.5 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK61378.1 - 0.00044 19.6 2.3 0.0097 15.2 0.0 2.1 2 0 0 2 2 2 2 Beta-1,3-glucanase Thaumatin PF00314.17 KIK61379.1 - 5.6e-74 248.4 10.3 6.4e-74 248.2 10.3 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK61379.1 - 2.8e-05 23.6 1.6 0.00052 19.4 0.1 2.1 2 0 0 2 2 2 2 Beta-1,3-glucanase Glucan_synthase PF02364.15 KIK61380.1 - 0 1306.8 0.0 0 1306.5 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIK61380.1 - 2.7e-43 147.4 0.2 8e-43 145.9 0.2 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 F-box-like PF12937.7 KIK61382.1 - 2.1e-05 24.3 2.0 3.2e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK61382.1 - 0.00075 19.8 2.2 4.8 7.8 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KIK61383.1 - 2.7e-24 85.7 0.0 4.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Velvet PF11754.8 KIK61384.1 - 8.5e-42 143.8 0.1 1.1e-41 143.5 0.1 1.1 1 0 0 1 1 1 1 Velvet factor Axin_b-cat_bind PF08833.10 KIK61384.1 - 5 7.3 8.7 8.2 6.6 0.5 3.0 2 0 0 2 2 2 0 Axin beta-catenin binding domain Sod_Fe_C PF02777.18 KIK61386.1 - 3.8e-37 126.5 0.5 5.9e-37 125.9 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIK61386.1 - 5.2e-31 106.9 3.7 5.2e-31 106.9 3.7 2.0 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cytochrome_P460 PF16694.5 KIK61386.1 - 0.057 13.8 0.4 0.13 12.6 0.4 1.7 1 1 0 1 1 1 0 Cytochrome P460 Smg4_UPF3 PF03467.15 KIK61387.1 - 5.8e-07 29.7 0.0 6.5e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Smg-4/UPF3 family RTX PF02382.15 KIK61387.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein F-box-like PF12937.7 KIK61388.1 - 0.01 15.7 0.6 0.05 13.5 0.2 2.4 2 0 0 2 2 2 0 F-box-like DUF2207 PF09972.9 KIK61389.1 - 0.021 13.6 0.1 0.022 13.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SieB PF14163.6 KIK61389.1 - 0.096 12.2 0.9 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF2618 PF10940.8 KIK61389.1 - 0.12 12.2 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) LysM PF01476.20 KIK61392.1 - 7.1e-19 67.6 0.0 6.8e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 LysM domain Phage_CI_repr PF07022.13 KIK61392.1 - 0.013 15.6 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain TIL PF01826.17 KIK61392.1 - 0.13 12.5 5.0 0.17 12.2 0.6 2.7 3 0 0 3 3 3 0 Trypsin Inhibitor like cysteine rich domain Peptidase_C1 PF00112.23 KIK61392.1 - 1.5 8.9 3.8 1.3 9.1 0.1 2.0 1 1 1 2 2 2 0 Papain family cysteine protease Spo7 PF03907.13 KIK61394.1 - 3.1e-43 147.8 0.0 5e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 KIK61394.1 - 0.0065 16.9 0.3 0.0065 16.9 0.3 2.4 2 1 0 2 2 2 1 Transmembrane protein 188 DUF4131 PF13567.6 KIK61395.1 - 0.0058 16.3 0.1 0.007 16.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) PrgI PF12666.7 KIK61395.1 - 0.024 15.4 0.7 0.034 14.9 0.7 1.2 1 0 0 1 1 1 0 PrgI family protein Asparaginase PF00710.20 KIK61397.1 - 0.012 15.1 0.3 0.019 14.5 0.3 1.2 1 0 0 1 1 1 0 Asparaginase, N-terminal ETF_QO PF05187.13 KIK61398.1 - 6.5e-34 116.2 0.2 6.7e-27 93.7 0.1 2.4 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KIK61398.1 - 7.3e-06 26.1 0.1 2.7e-05 24.3 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK61398.1 - 0.00017 21.3 0.6 0.0059 16.2 0.3 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK61398.1 - 0.0024 17.1 0.1 0.0037 16.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK61398.1 - 0.0025 17.1 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KIK61398.1 - 0.012 14.8 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KIK61398.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK61398.1 - 0.013 14.8 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK61398.1 - 0.017 13.9 0.1 0.028 13.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Fer4_7 PF12838.7 KIK61398.1 - 0.021 15.4 0.3 0.049 14.2 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 KIK61398.1 - 0.054 13.5 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fer4_10 PF13237.6 KIK61398.1 - 0.14 12.3 0.6 0.29 11.3 0.6 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 KIK61398.1 - 0.2 10.7 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIK61398.1 - 0.22 10.5 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_6 PF12837.7 KIK61398.1 - 2.3 8.5 4.3 1.4 9.1 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Glyco_hydro_20 PF00728.22 KIK61401.1 - 1.9e-79 267.6 0.0 2.5e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIK61401.1 - 1.4e-14 55.0 0.0 2.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIK61401.1 - 1.9e-08 35.1 0.0 8.8e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 EspB PF05802.11 KIK61401.1 - 0.0096 15.9 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 1 Enterobacterial EspB protein F-box-like PF12937.7 KIK61402.1 - 3.9e-06 26.7 5.3 1.4e-05 24.9 5.3 2.0 1 1 0 1 1 1 1 F-box-like Actino_peptide PF14408.6 KIK61403.1 - 0.12 12.5 1.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes SKG6 PF08693.10 KIK61404.1 - 0.0074 15.7 0.6 0.014 14.8 0.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CE2_N PF17996.1 KIK61404.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal CD34_antigen PF06365.12 KIK61404.1 - 0.022 14.4 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Syndecan PF01034.20 KIK61404.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KIK61404.1 - 0.078 13.9 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KIK61404.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 KIK61404.1 - 0.12 12.3 1.1 0.31 11.0 1.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SIT PF15330.6 KIK61404.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Adeno_E3_CR2 PF02439.15 KIK61404.1 - 0.25 11.1 0.6 0.47 10.3 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Methyltransf_23 PF13489.6 KIK61405.1 - 1.8e-11 44.2 0.0 2.4e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61405.1 - 8.3e-08 32.8 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61405.1 - 2.4e-05 23.8 0.0 0.00011 21.6 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61405.1 - 0.00039 20.3 0.0 0.00075 19.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61405.1 - 0.0042 17.7 0.0 0.0083 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK61406.1 - 3.6e-10 39.9 0.0 1.3e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61406.1 - 3.8e-08 33.9 0.0 6.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61406.1 - 1.7e-05 24.3 0.0 5.1e-05 22.7 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61406.1 - 0.00033 20.5 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61406.1 - 0.0061 17.2 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK61406.1 - 0.076 13.8 0.0 0.29 11.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK61407.1 - 1.1e-09 38.4 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61407.1 - 1.2e-05 25.9 0.0 3e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61407.1 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61407.1 - 0.034 13.9 0.0 0.064 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61407.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MNHE PF01899.16 KIK61408.1 - 0.45 10.3 6.5 0.67 9.7 6.5 1.4 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit TB2_DP1_HVA22 PF03134.19 KIK61410.1 - 2.4e-20 72.2 2.0 4e-20 71.5 2.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Phage_Coat_Gp8 PF05371.12 KIK61411.1 - 0.29 10.9 1.7 0.61 9.9 1.7 1.6 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Yippee-Mis18 PF03226.14 KIK61414.1 - 0.53 10.5 0.1 0.53 10.5 0.1 1.9 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Peptidase_S8 PF00082.22 KIK61415.1 - 2.1e-36 125.7 4.6 3.4e-36 125.1 4.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KIK61415.1 - 7.4e-21 74.0 0.1 1.8e-20 72.8 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain FAD_binding_4 PF01565.23 KIK61416.1 - 7.3e-17 61.4 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK61416.1 - 3.4e-07 30.3 0.5 8.2e-07 29.0 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like LRR_8 PF13855.6 KIK61417.1 - 2.5e-48 161.7 55.4 6.8e-10 38.6 1.8 10.2 7 2 5 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 KIK61417.1 - 3.1e-46 154.6 55.9 3.1e-07 30.6 0.4 12.6 9 2 4 14 14 14 11 Leucine Rich repeats (2 copies) PP2C PF00481.21 KIK61417.1 - 3.7e-39 134.9 0.0 8.6e-39 133.7 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_1 PF00560.33 KIK61417.1 - 2.4e-09 36.4 54.3 1.3 9.9 0.2 16.8 18 1 0 18 18 18 4 Leucine Rich Repeat LRR_9 PF14580.6 KIK61417.1 - 4.3e-06 26.3 12.6 0.35 10.3 0.3 5.6 5 1 2 7 7 7 3 Leucine-rich repeat LRR_6 PF13516.6 KIK61417.1 - 3.5e-05 23.5 58.7 1.3 9.3 0.2 14.6 16 0 0 16 16 16 5 Leucine Rich repeat Pkinase_Tyr PF07714.17 KIK61418.1 - 1.9e-36 125.7 0.0 3.4e-36 124.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK61418.1 - 2.8e-29 102.3 0.0 4.1e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK61418.1 - 0.004 16.5 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK61418.1 - 0.0084 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK61418.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK61418.1 - 0.026 14.4 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.7 KIK61419.1 - 1.9e-50 168.0 60.2 3.1e-06 27.4 0.4 12.6 9 1 6 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK61419.1 - 2.6e-46 155.2 58.9 2.7e-09 36.6 0.2 10.4 7 3 4 12 12 12 11 Leucine rich repeat PP2C PF00481.21 KIK61419.1 - 2.8e-41 141.9 0.0 5.6e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 KIK61419.1 - 3.6e-08 33.1 19.0 0.007 15.9 0.3 6.1 3 3 4 7 7 7 3 Leucine-rich repeat LRR_1 PF00560.33 KIK61419.1 - 1.2e-05 25.2 62.3 1.1 10.1 0.3 16.5 18 1 1 19 19 19 5 Leucine Rich Repeat LRR_6 PF13516.6 KIK61419.1 - 3.2e-05 23.6 58.2 0.088 12.9 0.2 14.9 17 0 0 17 17 17 4 Leucine Rich repeat PalH PF08733.10 KIK61420.1 - 0.012 14.6 7.3 0.4 9.6 0.1 2.2 2 0 0 2 2 2 0 PalH/RIM21 VirB8 PF04335.13 KIK61420.1 - 0.21 11.4 2.0 0.48 10.2 0.1 2.4 2 0 0 2 2 2 0 VirB8 protein Meth_synt_2 PF01717.18 KIK61421.1 - 2.7e-113 378.5 0.0 3.8e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIK61421.1 - 0.0019 17.8 0.0 0.0045 16.5 0.0 1.6 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KIK61421.1 - 0.0058 16.3 0.4 0.013 15.2 0.4 1.6 1 0 0 1 1 1 1 Short C-terminal domain DNA_pol3_theta PF06440.11 KIK61421.1 - 0.056 13.1 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, theta subunit LRR_4 PF12799.7 KIK61422.1 - 2.4e-44 148.6 62.5 4e-06 27.1 0.3 11.9 8 3 2 11 11 11 10 Leucine Rich repeats (2 copies) PP2C PF00481.21 KIK61422.1 - 6e-43 147.3 0.0 1.3e-42 146.2 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KIK61422.1 - 3.7e-42 141.9 68.6 8.7e-10 38.2 4.3 11.7 7 3 5 12 12 12 10 Leucine rich repeat LRR_9 PF14580.6 KIK61422.1 - 1.3e-08 34.5 17.4 0.0072 15.9 1.2 6.1 4 2 1 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 KIK61422.1 - 1.4e-05 24.8 51.0 0.37 11.0 0.4 13.1 14 0 0 14 14 14 4 Leucine Rich repeat LRR_1 PF00560.33 KIK61422.1 - 1.6e-05 24.8 56.6 0.58 10.9 0.9 15.9 16 1 0 16 16 16 4 Leucine Rich Repeat LRR_5 PF13306.6 KIK61422.1 - 0.0027 17.7 0.4 4.9 7.1 0.0 3.4 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) AAA_lid_4 PF17864.1 KIK61422.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain BBE PF08031.12 KIK61423.1 - 0.06 13.5 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Berberine and berberine like PalH PF08733.10 KIK61424.1 - 0.00081 18.5 8.5 0.18 10.8 0.1 2.1 2 0 0 2 2 2 2 PalH/RIM21 VirB8 PF04335.13 KIK61424.1 - 0.12 12.2 1.4 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 VirB8 protein Meth_synt_2 PF01717.18 KIK61426.1 - 4e-148 493.0 0.0 4.3e-144 479.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIK61426.1 - 2e-115 385.6 0.0 1.5e-109 366.4 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KIK61426.1 - 3.8 7.4 6.5 0.48 10.2 0.9 2.5 2 0 0 2 2 2 0 Short C-terminal domain R3H PF01424.22 KIK61432.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 R3H domain A_amylase_inhib PF01356.19 KIK61432.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase inhibitor DUF373 PF04123.13 KIK61433.1 - 0.0034 16.9 1.7 0.0034 16.9 1.7 1.7 1 1 0 2 2 2 1 Domain of unknown function (DUF373) P5-ATPase PF12409.8 KIK61433.1 - 0.056 13.6 3.2 0.069 13.3 1.0 2.2 2 0 0 2 2 2 0 P5-type ATPase cation transporter DUF4690 PF15756.5 KIK61433.1 - 0.23 12.1 0.2 0.23 12.1 0.2 2.5 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Bac_export_2 PF01312.19 KIK61433.1 - 9.7 5.3 8.9 14 4.7 1.4 2.2 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Fes1 PF08609.10 KIK61434.1 - 2.2e-28 99.0 3.1 2.2e-28 99.0 3.1 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 KIK61434.1 - 0.00056 19.2 0.0 0.00077 18.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 KIK61434.1 - 0.00064 20.1 3.8 0.0059 17.0 0.3 3.5 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 KIK61434.1 - 0.002 18.2 0.1 1.1 9.7 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 KIK61434.1 - 0.025 14.6 0.0 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK61434.1 - 0.026 15.0 2.9 7.5 7.2 0.0 3.9 4 1 0 4 4 4 0 HEAT-like repeat DUF5561 PF17716.1 KIK61434.1 - 0.056 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5561) Ank_2 PF12796.7 KIK61436.1 - 3.6e-31 107.6 7.0 3.7e-16 59.5 3.8 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK61436.1 - 6.7e-19 68.0 3.9 7.7e-09 35.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK61436.1 - 5.5e-17 61.4 7.4 3.8e-06 27.1 0.5 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KIK61436.1 - 3.6e-15 54.6 6.5 6e-06 26.2 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KIK61436.1 - 9.2e-14 51.3 7.2 4.1e-06 27.0 0.2 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Goodbye PF17109.5 KIK61437.1 - 4.1e-18 66.0 0.3 1.8e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NPV_P10 PF05531.12 KIK61437.1 - 0.015 15.7 6.0 9.9 6.7 0.0 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Terminase_2 PF03592.16 KIK61437.1 - 0.045 14.2 0.7 0.094 13.2 0.3 1.7 2 0 0 2 2 2 0 Terminase small subunit DUF4860 PF16152.5 KIK61438.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4860) Transp_cyt_pur PF02133.15 KIK61440.1 - 0.00014 20.8 1.7 0.065 12.0 0.3 2.3 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin SUFU PF05076.13 KIK61442.1 - 0.086 12.8 0.4 0.2 11.6 0.1 1.7 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) DUF3684 PF12449.8 KIK61443.1 - 3.1e-09 35.3 0.1 3.2e-09 35.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Transp_cyt_pur PF02133.15 KIK61445.1 - 1.8e-37 129.2 36.4 4e-36 124.7 36.4 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5316 PF17247.2 KIK61447.1 - 0.5 10.4 4.0 3 7.9 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5316) SPC25 PF06703.11 KIK61447.1 - 7.5 6.3 10.7 1.6 8.5 0.8 2.6 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Oxidored_FMN PF00724.20 KIK61448.1 - 2.9e-75 253.7 0.0 1.2e-69 235.2 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KIK61449.1 - 4.6e-95 318.8 0.0 5.4e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Methyltransf_23 PF13489.6 KIK61450.1 - 1.6e-10 41.0 0.0 2.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61450.1 - 7.1e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61450.1 - 4.9e-05 22.8 0.0 8.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK61450.1 - 0.0015 19.1 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61450.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK61451.1 - 3.5e-12 46.5 0.0 5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61451.1 - 2.4e-07 31.4 0.0 3.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61451.1 - 0.00061 19.2 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61451.1 - 0.0013 18.5 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61451.1 - 0.0053 17.4 0.0 0.0086 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK61452.1 - 2.5e-12 46.9 0.0 5.4e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61452.1 - 2e-06 28.4 0.0 3.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61452.1 - 3.8e-05 23.2 0.0 8.6e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61452.1 - 0.0049 16.7 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61452.1 - 0.017 15.8 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KIK61452.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KIK61453.1 - 3.7e-10 39.9 0.0 8.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61453.1 - 6.1e-06 26.8 0.0 9.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61453.1 - 0.00087 18.7 0.1 0.014 14.7 0.1 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK61453.1 - 0.033 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61453.1 - 0.061 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIK61453.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KIK61455.1 - 1.8e-13 50.6 0.0 2.3e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61455.1 - 1.5e-07 32.0 0.0 2.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK61455.1 - 1.5e-06 27.7 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK61455.1 - 0.0014 19.2 0.0 0.0024 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK61455.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Abhydrolase_6 PF12697.7 KIK61456.1 - 2.5e-05 25.0 1.6 5.3e-05 23.9 1.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK61456.1 - 0.051 12.8 0.0 8.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Glyco_transf_15 PF01793.16 KIK61457.1 - 3.8e-110 368.2 7.1 4.6e-110 367.9 7.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase BNR PF02012.20 KIK61457.1 - 0.094 12.8 0.3 0.23 11.6 0.3 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat VPS13 PF16908.5 KIK61458.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Glyco_transf_15 PF01793.16 KIK61459.1 - 2.4e-14 53.3 8.5 8.2e-08 31.9 0.7 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase VPS13 PF16908.5 KIK61460.1 - 0.042 13.6 0.2 0.09 12.6 0.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal DUF4164 PF13747.6 KIK61460.1 - 4 7.8 7.1 0.47 10.8 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Pkinase_fungal PF17667.1 KIK61461.1 - 9.5e-34 116.8 0.0 1.2e-28 100.1 0.1 2.1 2 0 0 2 2 2 2 Fungal protein kinase VPS13 PF16908.5 KIK61463.1 - 0.0013 18.6 0.3 0.0038 17.1 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Gp-FAR-1 PF05823.12 KIK61463.1 - 0.43 10.9 3.2 0.94 9.8 0.7 2.5 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CENP-Q PF13094.6 KIK61463.1 - 1.4 9.1 4.6 3.7 7.7 0.1 3.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HIP1_clath_bdg PF16515.5 KIK61463.1 - 4.3 8.0 8.0 1.8 9.3 2.4 3.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TBCC_N PF16752.5 KIK61463.1 - 8 6.9 13.2 21 5.6 0.0 5.1 5 1 1 6 6 6 0 Tubulin-specific chaperone C N-terminal domain UBN_AB PF14075.6 KIK61464.1 - 2.9e-09 37.0 1.0 2.9e-09 37.0 1.0 2.6 2 1 0 2 2 2 1 Ubinuclein conserved middle domain ZapB PF06005.12 KIK61464.1 - 0.0074 16.7 3.7 0.0074 16.7 3.7 3.7 3 0 0 3 3 3 2 Cell division protein ZapB betaPIX_CC PF16523.5 KIK61464.1 - 0.052 13.4 8.4 0.55 10.1 3.3 2.9 1 1 1 2 2 2 0 betaPIX coiled coil bZIP_1 PF00170.21 KIK61464.1 - 0.06 13.5 0.7 0.06 13.5 0.7 3.4 3 1 0 3 3 3 0 bZIP transcription factor Bap31_Bap29_C PF18035.1 KIK61464.1 - 0.1 12.6 8.8 0.05 13.6 2.5 3.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pre-PUA PF17832.1 KIK61464.1 - 3 8.6 7.2 1.4 9.6 0.2 3.5 2 2 1 3 3 3 0 Pre-PUA-like domain Ubiquitin_5 PF18037.1 KIK61464.1 - 4.5 7.7 9.4 16 5.9 1.0 3.5 3 0 0 3 3 3 0 Ubiquitin-like domain UBN_AB PF14075.6 KIK61465.1 - 3.5e-22 79.2 1.6 3.5e-22 79.2 1.6 3.1 2 2 1 3 3 3 1 Ubinuclein conserved middle domain THOC7 PF05615.13 KIK61465.1 - 0.0098 16.2 4.4 0.0098 16.2 4.4 3.9 3 1 0 4 4 4 1 Tho complex subunit 7 TcpS PF17456.2 KIK61465.1 - 0.01 15.9 1.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Lectin_N PF03954.14 KIK61465.1 - 0.67 9.7 7.8 19 5.0 0.6 3.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain PBP1_TM PF14812.6 KIK61465.1 - 7.2 7.1 11.0 16 5.9 6.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UBN_AB PF14075.6 KIK61466.1 - 3.5e-15 56.3 6.5 1.8e-10 40.9 1.3 2.5 1 1 1 2 2 2 2 Ubinuclein conserved middle domain TipAS PF07739.13 KIK61466.1 - 0.021 15.4 0.2 0.069 13.7 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DinI PF06183.13 KIK61466.1 - 0.027 14.8 0.0 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 DinI-like family AAA PF00004.29 KIK61467.1 - 1.4e-16 61.1 0.0 4.5e-15 56.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIK61467.1 - 0.00017 20.8 0.0 0.00032 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK61467.1 - 0.00045 20.7 0.0 0.00068 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIK61467.1 - 0.0031 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KIK61467.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KIK61467.1 - 0.0098 16.4 0.0 0.022 15.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KIK61467.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK61467.1 - 0.014 15.3 0.0 0.092 12.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KIK61467.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KIK61467.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BCS1_N PF08740.11 KIK61467.1 - 0.041 13.9 0.2 0.096 12.7 0.1 1.6 2 0 0 2 2 1 0 BCS1 N terminal RNA_helicase PF00910.22 KIK61467.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 KIK61467.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 KIK61467.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 KIK61467.1 - 0.082 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 KIK61467.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KIK61467.1 - 0.09 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK61467.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIK61467.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KIK61467.1 - 0.15 12.6 0.1 1.1 9.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIK61467.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Polysacc_deac_1 PF01522.21 KIK61468.1 - 2.1e-21 76.1 0.0 4.8e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide deacetylase Secretin_N_2 PF07655.13 KIK61468.1 - 0.13 12.8 8.1 0.72 10.4 5.5 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain AAA PF00004.29 KIK61469.1 - 6.8e-16 58.9 0.0 5.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KIK61469.1 - 2.3e-13 50.5 0.0 2.2e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 BCS1 N terminal DUF815 PF05673.13 KIK61469.1 - 0.00044 19.5 0.0 0.0008 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK61469.1 - 0.00063 20.2 0.0 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KIK61469.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KIK61469.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KIK61469.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK61469.1 - 0.027 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KIK61469.1 - 0.028 14.4 0.0 0.098 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KIK61469.1 - 0.048 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KIK61469.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KIK61469.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KIK61469.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ATPase PF06745.13 KIK61469.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiC ATP-synt_ab PF00006.25 KIK61469.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KIK61469.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KIK61469.1 - 0.2 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIK61469.1 - 0.23 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Polysacc_deac_1 PF01522.21 KIK61470.1 - 2.3e-24 85.7 0.0 4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Secretin_N_2 PF07655.13 KIK61470.1 - 0.03 14.9 8.4 0.16 12.5 5.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF2407 PF10302.9 KIK61471.1 - 0.12 13.0 1.7 0.33 11.5 1.7 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF4404 PF14357.6 KIK61471.1 - 2.2 9.0 12.3 2.7 8.7 1.7 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) Fib_alpha PF08702.10 KIK61471.1 - 8.1 6.6 11.9 7.9 6.7 0.1 3.2 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Acetyltransf_1 PF00583.25 KIK61472.1 - 1.6e-06 28.4 0.0 2.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK61472.1 - 1.8e-05 25.0 0.0 5.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK61472.1 - 5.1e-05 23.2 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK61472.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pkinase_fungal PF17667.1 KIK61474.1 - 0.0093 14.8 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase UBN_AB PF14075.6 KIK61475.1 - 2.8e-20 73.0 2.7 2.8e-20 73.0 2.7 2.8 2 1 0 2 2 2 1 Ubinuclein conserved middle domain ING PF12998.7 KIK61475.1 - 4.6 7.9 12.8 2.6 8.7 2.1 4.0 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding KDZ PF18758.1 KIK61478.1 - 1.8e-06 27.7 1.3 2e-06 27.6 1.3 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase UCH_1 PF13423.6 KIK61478.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CxC4 PF18717.1 KIK61479.1 - 1.5e-44 151.0 0.9 3e-44 150.1 0.3 1.9 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases zf-TFIIB PF13453.6 KIK61479.1 - 0.0077 15.5 0.9 2.7 7.4 0.0 2.6 2 0 0 2 2 2 2 Transcription factor zinc-finger APG6_N PF17675.1 KIK61480.1 - 0.0027 18.2 1.5 0.0033 17.9 1.5 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Oxidored_FMN PF00724.20 KIK61480.1 - 0.068 12.4 0.0 0.072 12.4 0.0 1.0 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.7 KIK61484.1 - 2.9e-06 27.1 0.1 0.00016 21.5 0.0 3.4 3 0 0 3 3 3 1 F-box-like NOG1_N PF17835.1 KIK61484.1 - 0.051 13.6 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain F-box PF00646.33 KIK61484.1 - 0.084 12.8 1.6 0.26 11.2 0.0 2.7 3 0 0 3 3 3 0 F-box domain CDC48_N PF02359.18 KIK61486.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain DUF1866 PF08952.11 KIK61488.1 - 0.046 13.6 0.3 0.086 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) YdfA_immunity PF12127.8 KIK61488.1 - 1.1 8.3 4.0 1.5 7.8 4.0 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial KASH_CCD PF14662.6 KIK61488.1 - 1.2 8.9 23.5 0.038 13.8 5.3 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Asp-B-Hydro_N PF05279.11 KIK61488.1 - 2.6 8.1 12.3 4 7.4 12.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIA PF03153.13 KIK61488.1 - 3.3 7.6 13.5 3.2 7.7 12.8 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBN_AB PF14075.6 KIK61489.1 - 5.4e-18 65.5 3.2 2e-17 63.6 0.1 2.9 2 1 0 2 2 2 1 Ubinuclein conserved middle domain DUF4686 PF15742.5 KIK61489.1 - 0.0096 15.1 14.8 0.014 14.5 14.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) ZapB PF06005.12 KIK61489.1 - 0.024 15.1 23.1 0.19 12.2 3.6 3.2 2 1 0 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 KIK61489.1 - 0.13 11.4 12.8 0.31 10.1 12.2 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 KIK61489.1 - 0.23 12.4 11.3 2.9 8.9 0.0 3.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain XRCC4 PF06632.12 KIK61489.1 - 0.28 10.0 11.6 0.53 9.1 11.6 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 KASH_CCD PF14662.6 KIK61489.1 - 0.37 10.6 18.4 0.29 11.0 5.6 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH PKcGMP_CC PF16808.5 KIK61489.1 - 0.47 10.3 10.2 0.083 12.8 3.4 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MAD PF05557.13 KIK61489.1 - 0.53 8.6 18.1 0.084 11.2 6.5 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein UPF0242 PF06785.11 KIK61489.1 - 0.68 10.0 14.9 0.63 10.1 13.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KIK61489.1 - 1.3 8.3 8.7 2.7 7.3 8.7 1.5 1 0 0 1 1 1 0 FAM76 protein bZIP_1 PF00170.21 KIK61489.1 - 1.6 8.9 18.1 1.4 9.0 1.7 4.1 3 1 1 4 4 3 0 bZIP transcription factor FUSC PF04632.12 KIK61489.1 - 1.6 7.1 3.2 2.4 6.6 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 KIK61489.1 - 1.8 7.1 7.4 2.9 6.4 7.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Leu_zip PF15294.6 KIK61489.1 - 1.8 8.0 16.1 4.4 6.7 4.4 2.3 1 1 1 2 2 2 0 Leucine zipper TMF_TATA_bd PF12325.8 KIK61489.1 - 2.4 8.4 14.0 6.2 7.1 13.3 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Wtap PF17098.5 KIK61489.1 - 3.1 7.7 14.0 7.5 6.5 5.6 2.7 1 1 1 2 2 2 0 WTAP/Mum2p family Fez1 PF06818.15 KIK61489.1 - 3.1 8.2 16.6 6.2 7.2 16.6 1.4 1 0 0 1 1 1 0 Fez1 Tropomyosin_1 PF12718.7 KIK61489.1 - 3.9 7.6 20.3 15 5.8 4.5 2.1 1 1 1 2 2 2 0 Tropomyosin like SlyX PF04102.12 KIK61489.1 - 5.9 7.6 10.1 3.5 8.3 3.8 3.2 2 1 1 3 3 3 0 SlyX EphA2_TM PF14575.6 KIK61490.1 - 0.018 15.9 0.6 0.033 15.0 0.6 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KIK61490.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.12 KIK61490.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Popeye PF04831.13 KIK61493.1 - 9.1 6.5 7.5 0.4 10.9 0.7 2.2 2 0 0 2 2 2 0 Popeye protein conserved region CE2_N PF17996.1 KIK61494.1 - 1.9e-06 27.8 0.0 7.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Orf78 PF06024.12 KIK61494.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) SKG6 PF08693.10 KIK61494.1 - 0.0017 17.8 0.8 0.0031 16.9 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KIK61494.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 CD34_antigen PF06365.12 KIK61494.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 KIK61494.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 KIK61494.1 - 0.04 13.8 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Rifin DUF4448 PF14610.6 KIK61494.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 KIK61494.1 - 0.13 12.0 0.6 0.22 11.3 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KIK61494.1 - 0.13 13.1 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 KIK61494.1 - 0.15 11.8 0.1 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Iso_dh PF00180.20 KIK61495.1 - 1.6e-15 57.2 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CE2_N PF17996.1 KIK61498.1 - 1.2e-06 28.5 0.0 4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal TMEM154 PF15102.6 KIK61498.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 KIK61498.1 - 0.023 14.1 0.5 0.038 13.4 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KIK61498.1 - 0.099 12.4 1.3 0.16 11.7 1.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM51 PF15345.6 KIK61498.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Syndecan PF01034.20 KIK61498.1 - 0.18 11.7 0.6 0.36 10.8 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KIK61498.1 - 0.19 12.6 0.0 0.37 11.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 KIK61498.1 - 0.21 11.4 0.0 0.3 10.9 0.0 1.1 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 KIK61498.1 - 0.24 10.2 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless Iso_dh PF00180.20 KIK61499.1 - 4.4e-73 246.4 0.0 5.3e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sof1 PF04158.14 KIK61503.1 - 3.5e-27 94.5 8.9 6.6e-27 93.6 8.9 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KIK61503.1 - 1.9e-24 85.4 11.2 5.1e-08 33.5 0.4 6.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK61503.1 - 2.6e-08 34.0 0.0 0.87 9.9 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_28 PF00295.17 KIK61504.1 - 4.6e-40 137.6 1.4 8.3e-40 136.8 1.4 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 PknG_rubred PF16919.5 KIK61505.1 - 9.4 6.4 8.1 98 3.1 8.1 2.4 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain NAD_binding_6 PF08030.12 KIK61511.1 - 5.1e-37 127.4 0.0 1e-36 126.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK61511.1 - 4.5e-23 81.4 0.0 9.6e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIK61511.1 - 2.3e-18 66.5 10.5 2.3e-18 66.5 10.5 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KIK61511.1 - 0.18 12.5 0.0 3 8.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain COX14 PF14880.6 KIK61511.1 - 1.4 8.8 3.1 3.9 7.4 1.3 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Glycos_transf_3 PF00591.21 KIK61512.1 - 8.9e-76 254.8 0.0 1.1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIK61512.1 - 3.9e-05 23.4 0.0 8.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain TPP_enzyme_N PF02776.18 KIK61513.1 - 4.1e-37 127.4 0.2 9.5e-37 126.2 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIK61513.1 - 3.8e-13 49.5 0.0 2.5e-12 46.9 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK61513.1 - 1.1e-05 25.2 0.0 0.00011 21.9 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 KIK61513.1 - 0.00053 18.9 0.1 0.0008 18.3 0.1 1.2 1 0 0 1 1 1 1 XFP N-terminal domain Vps26 PF03643.15 KIK61514.1 - 9.2e-130 431.6 2.4 1.1e-129 431.4 2.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KIK61514.1 - 0.00018 21.6 0.6 0.12 12.4 0.0 3.2 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SGL PF08450.12 KIK61515.1 - 4.8e-06 26.3 0.4 0.012 15.2 0.1 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region MRJP PF03022.16 KIK61515.1 - 0.045 13.1 0.2 0.24 10.7 0.1 2.1 2 1 1 3 3 3 0 Major royal jelly protein PQQ PF01011.21 KIK61515.1 - 0.06 13.3 0.2 0.19 11.7 0.2 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Aminotran_3 PF00202.21 KIK61516.1 - 1e-109 366.9 0.0 1.3e-109 366.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIK61516.1 - 4e-05 23.0 0.0 5.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2_4 PF13894.6 KIK61517.1 - 1.3e-05 25.6 6.2 0.023 15.5 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK61517.1 - 5.1e-05 23.5 0.5 7.2e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 KIK61517.1 - 0.00056 20.2 4.0 0.017 15.4 0.3 2.7 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KIK61517.1 - 0.0028 18.3 3.4 0.036 14.7 0.4 2.6 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 KIK61517.1 - 0.0031 17.8 5.4 0.0054 17.0 5.4 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KIK61517.1 - 0.006 16.2 1.6 0.044 13.4 0.6 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KIK61517.1 - 0.0091 16.3 3.7 0.025 14.9 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KIK61517.1 - 0.011 16.2 7.8 0.049 14.1 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-RAG1 PF10426.9 KIK61517.1 - 0.015 15.4 4.2 0.17 12.1 0.0 3.1 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain zf-H2C2_2 PF13465.6 KIK61517.1 - 0.046 14.2 9.0 6.7 7.3 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Gin PF10764.9 KIK61517.1 - 0.078 13.0 1.0 0.25 11.3 0.3 2.1 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-TRAF PF02176.18 KIK61517.1 - 0.12 13.0 7.9 8.2 7.2 0.9 3.0 1 1 0 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.15 KIK61517.1 - 0.34 11.0 3.2 0.31 11.1 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger Pkinase_Tyr PF07714.17 KIK61518.1 - 0.097 11.9 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase O-ag_pol_Wzy PF14296.6 KIK61519.1 - 0.032 12.9 0.1 0.037 12.7 0.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Alpha_kinase PF02816.18 KIK61521.1 - 2.8e-16 60.2 0.9 4.3e-16 59.6 0.9 1.3 1 1 0 1 1 1 1 Alpha-kinase family DUF648 PF04890.13 KIK61522.1 - 0.0047 16.7 0.5 0.0066 16.3 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF648) DUF327 PF03885.13 KIK61522.1 - 0.021 14.8 0.9 0.035 14.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) HNF-1_N PF04814.13 KIK61528.1 - 0.6 10.7 3.5 0.61 10.7 2.7 1.4 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus GPHH PF16905.5 KIK61529.1 - 0.097 12.5 0.2 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated OTT_1508_deam PF14441.6 KIK61532.1 - 0.001 19.1 0.3 0.0021 18.0 0.3 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Pkinase PF00069.25 KIK61533.1 - 6.5e-37 127.3 0.0 7.2e-15 55.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61533.1 - 1.1e-13 51.1 0.2 0.00038 19.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase PrmA PF06325.13 KIK61533.1 - 0.09 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Snurportin1 PF11538.8 KIK61534.1 - 0.00011 22.3 2.0 0.00022 21.4 2.0 1.5 1 0 0 1 1 1 1 Snurportin1 WD40 PF00400.32 KIK61535.1 - 1.3e-17 63.8 7.8 0.0026 18.6 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK61535.1 - 9.6e-08 32.2 0.5 0.98 9.8 0.1 4.3 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK61535.1 - 0.011 14.7 0.1 4.8 6.0 0.1 3.5 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HEV_ORF1 PF02444.16 KIK61535.1 - 0.11 13.1 0.1 13 6.4 0.0 2.3 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) GMC_oxred_N PF00732.19 KIK61537.1 - 1.4e-64 218.3 0.0 2e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK61537.1 - 4.4e-34 118.1 0.1 6.8e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIK61537.1 - 0.0018 17.6 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK61537.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KIK61537.1 - 0.016 14.4 0.0 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK61537.1 - 0.032 13.3 0.2 0.053 12.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK61537.1 - 0.039 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK61537.1 - 0.045 13.3 0.1 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK61537.1 - 0.11 11.6 0.4 6.1 5.8 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Acetyltransf_9 PF13527.7 KIK61538.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK61538.1 - 0.13 12.2 0.0 6.8 6.7 0.0 2.7 3 0 0 3 3 3 0 FR47-like protein LSM PF01423.22 KIK61539.1 - 3.7e-19 68.2 1.4 4.7e-19 67.8 1.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK61539.1 - 0.0032 17.6 0.1 0.0041 17.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 KIK61539.1 - 0.014 15.2 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain PCNA_N PF00705.18 KIK61540.1 - 7e-52 174.5 2.8 1.6e-51 173.3 2.8 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KIK61540.1 - 3.8e-36 124.1 0.2 4.2e-17 62.5 0.1 2.6 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KIK61540.1 - 7e-05 22.4 0.0 0.00076 19.0 0.0 2.4 2 1 0 2 2 2 1 Rad9 Coilin_N PF15862.5 KIK61540.1 - 0.018 14.9 0.0 0.018 14.9 0.0 3.1 1 1 2 3 3 3 0 Coilin N-terminus GREB1 PF15782.5 KIK61540.1 - 0.084 10.0 3.7 0.087 9.9 3.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop14 PF04147.12 KIK61540.1 - 0.46 8.6 41.6 0.66 8.1 41.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF908 PF06012.12 KIK61540.1 - 0.94 8.8 5.1 1.4 8.2 5.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Raftlin PF15250.6 KIK61540.1 - 1.1 8.0 12.4 1.6 7.4 12.4 1.3 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.10 KIK61540.1 - 2.2 7.5 40.3 3.5 6.9 40.3 1.3 1 0 0 1 1 1 0 BUD22 PMSR PF01625.21 KIK61541.1 - 9.7e-59 197.9 0.3 1.2e-58 197.7 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CTK3_C PF12350.8 KIK61542.1 - 0.05 13.8 2.2 0.18 11.9 2.2 2.0 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Mus7 PF09462.10 KIK61545.1 - 1e-42 146.9 1.0 8.3e-42 143.8 1.0 2.2 1 1 0 1 1 1 1 Mus7/MMS22 family MMS22L_N PF14910.6 KIK61545.1 - 0.027 12.9 0.5 0.043 12.3 0.5 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal APG6_N PF17675.1 KIK61545.1 - 0.4 11.2 12.6 2.8 8.5 0.4 2.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Polysacc_deac_1 PF01522.21 KIK61546.1 - 2.3e-27 95.3 0.0 3.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1561 PF07598.11 KIK61546.1 - 0.021 13.0 0.0 0.03 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) SDH_alpha PF03313.15 KIK61547.1 - 2.9e-101 338.5 0.3 3.9e-101 338.1 0.3 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KIK61547.1 - 2.8e-28 99.2 0.0 8.4e-28 97.7 0.0 1.8 1 1 0 1 1 1 1 Serine dehydratase beta chain RhoGAP PF00620.27 KIK61548.1 - 8.3e-43 145.8 0.0 1.5e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KIK61548.1 - 6.6e-16 58.7 0.0 2.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 PH domain PX PF00787.24 KIK61548.1 - 1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 KIK61548.1 - 0.0071 16.6 0.1 0.077 13.3 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain GCIP PF13324.6 KIK61548.1 - 0.51 9.9 3.7 1.2 8.6 3.7 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4637 PF15470.6 KIK61548.1 - 9.7 5.9 12.1 43 3.8 12.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ribosomal_L5_C PF00673.21 KIK61549.1 - 1e-23 83.3 0.0 1.7e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus GMC_oxred_N PF00732.19 KIK61550.1 - 2e-56 191.6 0.0 2.8e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK61550.1 - 3.9e-28 98.8 0.1 5.9e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK61550.1 - 0.00028 21.1 0.0 0.00089 19.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK61550.1 - 0.00035 19.8 0.0 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK61550.1 - 0.0017 17.5 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK61550.1 - 0.0035 17.0 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK61550.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK61550.1 - 0.039 13.2 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KIK61550.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Cytochrom_C1 PF02167.15 KIK61551.1 - 6.6e-97 323.5 0.0 8e-97 323.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KIK61551.1 - 0.00073 19.8 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KIK61551.1 - 0.0066 17.6 0.1 0.018 16.2 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c PET117 PF15786.5 KIK61551.1 - 0.15 12.3 0.2 0.3 11.4 0.2 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial CytochromB561_N PF09786.9 KIK61551.1 - 0.39 9.7 3.3 0.51 9.3 3.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Clathrin PF00637.20 KIK61552.1 - 6e-202 661.6 31.1 1.3e-31 109.4 0.3 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KIK61552.1 - 1.5e-36 122.9 0.8 5.7e-06 26.4 0.1 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KIK61552.1 - 4.3e-30 103.4 0.1 2.3e-29 101.1 0.0 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 KIK61552.1 - 1.7e-11 43.2 0.1 1.7e-11 43.2 0.1 3.3 4 0 0 4 4 4 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KIK61552.1 - 0.0018 17.4 9.0 0.75 8.8 0.1 4.7 5 0 0 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.6 KIK61552.1 - 0.0069 16.3 11.1 1.1 9.5 0.1 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK61552.1 - 0.032 15.0 17.0 0.83 10.6 0.1 8.4 8 1 1 9 9 8 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KIK61552.1 - 0.046 14.0 9.8 1.2 9.4 0.1 5.7 6 1 0 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 KIK61552.1 - 0.067 13.0 8.4 23 5.0 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK61552.1 - 0.76 10.0 11.7 69 3.9 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK61552.1 - 0.86 10.0 10.5 7.9 7.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1771 PF08590.10 KIK61553.1 - 6.3e-16 58.5 7.0 1.2e-15 57.6 7.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KIK61553.1 - 2.6e-09 36.8 9.3 2.1e-07 30.7 1.9 2.8 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KIK61553.1 - 4.2e-08 32.9 7.4 3.1e-06 27.0 0.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIK61553.1 - 4.3e-08 33.8 3.9 1.4e-06 29.0 0.1 2.6 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KIK61553.1 - 3.3e-05 23.6 16.9 0.00013 21.7 1.5 3.4 3 1 0 3 3 3 2 CCCH-type zinc finger Smr PF01713.21 KIK61553.1 - 4.7e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 KIK61553.1 - 0.00031 21.1 6.4 0.14 12.7 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIK61553.1 - 0.0012 19.1 3.4 0.54 10.5 0.2 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 KIK61553.1 - 0.0051 16.5 3.7 0.095 12.4 0.5 2.3 2 0 0 2 2 2 1 Putative zinc-finger domain HAD_2 PF13419.6 KIK61554.1 - 4.1e-21 75.9 0.0 5.8e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK61554.1 - 2.4e-07 31.2 0.0 2e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK61554.1 - 6.6e-05 22.9 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIK61554.1 - 0.00016 22.2 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Vitelline_membr PF10542.9 KIK61554.1 - 0.13 12.1 0.1 0.44 10.4 0.1 1.9 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region PI3K_p85B PF02192.16 KIK61554.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain Abhydrolase_6 PF12697.7 KIK61555.1 - 6.2e-17 62.9 0.6 7.9e-17 62.6 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family NIR_SIR PF01077.22 KIK61556.1 - 2.3e-46 157.2 0.0 1.8e-43 147.8 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIK61556.1 - 3.8e-33 113.1 0.1 5.5e-17 61.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KIK61556.1 - 3.3e-26 92.2 0.0 5.8e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Fungal_trans PF04082.18 KIK61557.1 - 1.3e-20 73.5 0.4 3.2e-20 72.3 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK61557.1 - 8.9e-07 28.9 6.4 1.6e-06 28.1 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FH2 PF02181.23 KIK61558.1 - 3e-05 23.3 7.1 0.004 16.3 1.8 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain Fez1 PF06818.15 KIK61558.1 - 0.0004 20.9 1.4 0.055 13.9 0.6 2.1 2 0 0 2 2 2 1 Fez1 ATG16 PF08614.11 KIK61558.1 - 0.00094 19.5 10.9 0.089 13.0 7.5 2.4 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Taxilin PF09728.9 KIK61558.1 - 0.001 18.3 4.0 0.0022 17.2 0.4 2.0 2 0 0 2 2 2 1 Myosin-like coiled-coil protein Atg14 PF10186.9 KIK61558.1 - 0.0022 17.1 5.7 0.074 12.1 2.7 2.3 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KIK61558.1 - 0.0072 15.3 11.7 0.13 11.1 0.2 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein ERM PF00769.19 KIK61558.1 - 0.018 14.9 7.4 0.15 11.8 3.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4618 PF15397.6 KIK61558.1 - 0.02 14.4 8.3 0.019 14.4 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 KIK61558.1 - 0.034 14.7 9.6 2.2 8.8 6.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2388 PF09498.10 KIK61558.1 - 0.093 12.7 0.4 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) TPR_MLP1_2 PF07926.12 KIK61558.1 - 0.11 12.5 14.0 0.33 11.0 0.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4062 PF13271.6 KIK61558.1 - 0.15 12.4 0.9 8.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) Filament PF00038.21 KIK61558.1 - 0.2 11.2 10.0 0.7 9.4 3.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein KxDL PF10241.9 KIK61558.1 - 0.27 11.6 4.6 1.5 9.2 2.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Metal_resist PF13801.6 KIK61558.1 - 0.57 10.4 8.2 0.19 11.9 3.2 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Sec8_exocyst PF04048.14 KIK61558.1 - 0.63 9.9 3.1 5.9 6.8 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2267 PF10025.9 KIK61558.1 - 0.7 10.2 5.4 0.15 12.4 1.5 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2267) COG2 PF06148.11 KIK61558.1 - 0.76 9.9 8.3 2.7 8.1 0.8 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.8 KIK61558.1 - 0.77 7.2 7.5 0.37 8.2 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 KIK61558.1 - 0.81 8.5 6.2 1.5 7.6 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 KIK61558.1 - 0.82 9.9 6.7 3.6 7.8 3.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.6 KIK61558.1 - 0.97 9.6 15.1 17 5.5 9.8 3.1 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.6 KIK61558.1 - 1.6 8.4 12.6 12 5.6 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Swi5 PF07061.11 KIK61558.1 - 1.7 8.8 4.5 3 8.0 0.2 2.4 2 0 0 2 2 2 0 Swi5 Mitofilin PF09731.9 KIK61558.1 - 1.8 7.3 8.8 0.18 10.6 3.5 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein YscO-like PF16789.5 KIK61558.1 - 2.3 8.2 10.0 1.9 8.5 2.7 2.1 2 0 0 2 2 2 0 YscO-like protein DUF1664 PF07889.12 KIK61558.1 - 2.4 8.2 4.4 19 5.3 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KIK61558.1 - 2.5 7.9 10.0 1.3 8.8 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 KIK61558.1 - 3.3 7.0 13.7 6.7 6.0 6.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 KIK61558.1 - 3.3 7.8 13.5 3.5 7.8 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin like SOGA PF11365.8 KIK61558.1 - 4.5 8.5 10.7 5.5 8.2 7.1 2.4 2 0 0 2 2 2 0 Protein SOGA DUF1090 PF06476.12 KIK61558.1 - 4.8 7.3 8.4 6.9 6.8 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) BRE1 PF08647.11 KIK61558.1 - 5.5 7.1 10.2 7.9 6.6 4.5 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DMPK_coil PF08826.10 KIK61558.1 - 9.2 6.5 11.0 11 6.3 4.3 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like Ras PF00071.22 KIK61559.1 - 3.4e-52 176.3 0.0 3.9e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK61559.1 - 1.3e-20 73.8 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK61559.1 - 7.1e-08 32.1 0.0 8.4e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK61559.1 - 0.00036 20.0 0.0 0.00079 18.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK61559.1 - 0.0092 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Skp1_POZ PF03931.15 KIK61559.1 - 0.014 15.5 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain RsgA_GTPase PF03193.16 KIK61559.1 - 0.025 14.5 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KIK61559.1 - 0.047 13.0 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KIK61559.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 KIK61560.1 - 1.7e-10 40.4 1.1 6e-10 38.6 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Carla_C4 PF01623.17 KIK61560.1 - 3 7.8 6.7 7.2 6.6 6.7 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Cation_efflux PF01545.21 KIK61561.1 - 3.4e-41 141.2 32.6 3.4e-41 141.2 32.6 3.1 3 1 0 3 3 3 1 Cation efflux family PX PF00787.24 KIK61563.1 - 3.3e-22 78.6 3.4 8.9e-22 77.2 0.0 3.3 4 0 0 4 4 4 1 PX domain Vps5 PF09325.10 KIK61563.1 - 2.5e-08 33.7 7.9 0.0002 21.0 0.8 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KIK61563.1 - 0.0014 18.3 5.9 0.0037 16.9 0.6 2.1 2 0 0 2 2 2 1 BAR domain DUF4391 PF14335.6 KIK61563.1 - 0.0057 16.4 0.7 0.014 15.2 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4391) Exonuc_VII_L PF02601.15 KIK61563.1 - 0.25 10.9 2.8 1.9 8.0 0.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KIK61563.1 - 0.28 11.7 1.4 1.5 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Sec8_exocyst PF04048.14 KIK61563.1 - 0.84 9.5 4.5 3.6 7.5 0.6 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF5339 PF17274.2 KIK61563.1 - 2.2 9.2 4.3 1.3 10.0 0.9 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5339) AAA_33 PF13671.6 KIK61564.1 - 2.6e-14 53.6 0.2 5.4e-12 46.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 KIK61564.1 - 6.2e-05 23.1 0.0 0.0001 22.4 0.0 1.5 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KIK61564.1 - 0.00036 21.1 0.0 0.016 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KIK61564.1 - 0.006 16.5 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase APS_kinase PF01583.20 KIK61564.1 - 0.0074 16.2 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 KIK61564.1 - 0.017 14.6 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 KIK61564.1 - 0.083 13.3 0.0 0.16 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain CPT PF07931.12 KIK61564.1 - 0.1 12.5 0.0 0.84 9.5 0.0 2.0 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 KIK61564.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 KIK61564.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KIK61564.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 KIK61564.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain VirE PF05272.11 KIK61564.1 - 0.24 11.1 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TPR_11 PF13414.6 KIK61565.1 - 6.9e-17 60.9 8.2 2.9e-06 26.8 0.1 4.5 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.17 KIK61565.1 - 1.8e-16 58.9 2.7 1.8e-06 27.6 0.0 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK61565.1 - 9.3e-16 56.9 0.4 2.5e-07 30.2 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK61565.1 - 6.4e-14 52.3 1.1 2.4e-06 28.1 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK61565.1 - 2e-11 44.2 0.6 0.00022 21.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK61565.1 - 9.3e-11 41.6 0.8 0.002 18.8 0.0 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK61565.1 - 1.4e-10 40.8 0.2 0.067 13.6 0.0 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK61565.1 - 4.6e-10 39.6 1.9 0.0036 17.6 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK61565.1 - 1.6e-08 34.1 2.5 0.0061 16.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK61565.1 - 5.9e-08 32.3 5.0 0.0013 18.6 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK61565.1 - 1.6e-05 25.3 0.4 0.027 15.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK61565.1 - 1.7e-05 24.2 0.1 2.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK61565.1 - 4.1e-05 23.7 0.8 0.056 13.7 0.3 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIK61565.1 - 5.9e-05 22.8 4.8 0.63 10.2 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat MIT PF04212.18 KIK61565.1 - 0.00036 20.5 2.8 1.3 9.1 0.0 3.2 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KIK61565.1 - 0.0015 18.9 0.2 0.74 10.6 0.0 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KIK61565.1 - 0.0063 16.8 0.6 0.027 14.8 0.1 2.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK61565.1 - 0.018 15.2 0.1 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KIK61565.1 - 0.027 14.5 0.1 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.6 KIK61565.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 KIK61565.1 - 0.049 13.1 1.1 2.6 7.4 0.1 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_5 PF12688.7 KIK61565.1 - 0.1 12.9 0.0 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat Tim17 PF02466.19 KIK61566.1 - 1.6e-25 89.6 7.0 2.1e-25 89.2 7.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Velvet PF11754.8 KIK61567.1 - 6.1e-20 72.2 5.8 1.5e-10 41.4 0.1 3.0 2 1 1 3 3 3 2 Velvet factor Velvet PF11754.8 KIK61568.1 - 0.013 15.5 0.0 0.014 15.4 0.0 1.0 1 0 0 1 1 1 0 Velvet factor CYSTM PF12734.7 KIK61569.1 - 3.3e-08 33.7 16.3 3.3e-08 33.7 16.3 4.0 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance DUF4813 PF16072.5 KIK61569.1 - 0.0059 16.3 17.4 0.0065 16.2 17.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) GRP PF07172.11 KIK61569.1 - 8.4 7.2 11.1 12 6.7 11.1 1.2 1 0 0 1 1 1 0 Glycine rich protein family Mito_carr PF00153.27 KIK61570.1 - 3.3e-28 97.5 9.0 8.1e-17 60.9 0.1 3.6 3 2 0 3 3 3 3 Mitochondrial carrier protein MRG PF05712.13 KIK61571.1 - 3.2e-54 183.2 0.3 4.2e-54 182.9 0.3 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KIK61571.1 - 1.1e-10 41.2 0.3 1.9e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KIK61571.1 - 0.037 13.9 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SHR3_chaperone PF08229.11 KIK61572.1 - 1.2e-45 154.8 0.2 1.3e-45 154.7 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 SCA7 PF08313.12 KIK61573.1 - 2.6e-29 100.9 0.2 2.6e-29 100.9 0.2 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain Plasmodium_Vir PF05795.11 KIK61573.1 - 0.29 10.5 5.1 0.38 10.1 5.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MAS20 PF02064.15 KIK61573.1 - 0.54 10.4 10.1 0.8 9.8 9.1 1.8 1 1 1 2 2 2 0 MAS20 protein import receptor DUF4407 PF14362.6 KIK61573.1 - 2.9 7.2 5.5 4.1 6.7 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 KIK61574.1 - 7.4e-33 114.8 0.1 1.2e-32 114.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KIK61574.1 - 0.0041 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain TRAUB PF08164.12 KIK61575.1 - 1.4e-30 105.7 0.3 3.7e-30 104.3 0.3 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KIK61575.1 - 1.2e-26 94.0 0.4 1.2e-26 94.0 0.4 2.6 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Pox_mRNA-cap PF03341.13 KIK61575.1 - 0.041 13.2 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit PMC2NT PF08066.12 KIK61575.1 - 0.18 12.5 2.2 0.59 10.9 0.3 2.9 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Aminotran_5 PF00266.19 KIK61576.1 - 8.8e-26 90.7 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KIK61576.1 - 0.0018 18.3 1.0 0.015 15.3 0.1 2.4 2 1 0 2 2 2 1 B12 binding domain F-box-like PF12937.7 KIK61577.1 - 1.9e-09 37.2 0.1 5.7e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like NIR_SIR PF01077.22 KIK61578.1 - 8.4e-54 181.4 0.1 1.4e-48 164.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIK61578.1 - 2e-33 114.0 0.1 1.3e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KIK61578.1 - 2.6e-32 112.0 0.0 6.9e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KIK61578.1 - 0.087 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain POR_N PF01855.19 KIK61578.1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PQ-loop PF04193.14 KIK61579.1 - 1.1e-19 70.0 9.5 5.9e-14 51.6 1.7 3.6 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK61579.1 - 0.0076 17.1 4.4 0.0076 17.1 4.4 1.5 1 1 0 1 1 1 1 ER lumen protein retaining receptor Metallophos PF00149.28 KIK61580.1 - 2.3e-39 136.0 0.4 2.9e-39 135.7 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK61580.1 - 7.9e-21 74.3 0.3 1.7e-20 73.2 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Dynamin_M PF01031.20 KIK61582.1 - 5.6e-36 124.2 0.0 1.3e-35 123.0 0.0 1.5 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK61582.1 - 1.6e-30 106.4 0.0 2.9e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK61582.1 - 3.4e-13 49.6 0.2 8.8e-13 48.2 0.1 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK61582.1 - 4.4e-06 26.7 0.1 7.2e-05 22.8 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIK61582.1 - 0.036 14.3 0.3 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain RE_SinI PF09570.10 KIK61582.1 - 0.076 12.2 0.1 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 SinI restriction endonuclease AAA_29 PF13555.6 KIK61582.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK61582.1 - 0.16 12.5 0.0 0.58 10.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter SH3_1 PF00018.28 KIK61584.1 - 7.3e-19 67.1 2.2 2.6e-08 33.3 0.1 2.9 2 1 0 2 2 2 2 SH3 domain SAM_1 PF00536.30 KIK61584.1 - 1.6e-13 50.9 0.0 3.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KIK61584.1 - 1.9e-13 50.1 1.1 9.6e-06 25.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.17 KIK61584.1 - 1.1e-11 44.7 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KIK61584.1 - 4.1e-07 29.6 0.3 9.1e-05 22.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 KIK61584.1 - 7.1e-07 29.8 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KIK61584.1 - 0.0013 19.0 3.7 0.24 11.7 0.3 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain DUF5632 PF18646.1 KIK61584.1 - 0.046 13.8 0.3 0.14 12.3 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5632) rve_3 PF13683.6 KIK61584.1 - 0.099 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain CTK3 PF12243.8 KIK61585.1 - 1.5e-29 102.5 0.0 2.4e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KIK61585.1 - 6.9e-25 87.0 4.0 1.2e-24 86.2 4.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus F-box-like PF12937.7 KIK61586.1 - 0.05 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like BRAP2 PF07576.12 KIK61587.1 - 7.2e-29 99.9 0.0 1.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KIK61587.1 - 1.1e-19 70.5 4.4 2.5e-19 69.4 4.4 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KIK61587.1 - 8e-08 32.5 9.6 8e-08 32.5 9.6 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK61587.1 - 1.3e-06 28.1 9.8 3.3e-06 26.8 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK61587.1 - 2.8e-05 23.7 5.1 8.5e-05 22.2 5.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KIK61587.1 - 2.9e-05 24.0 3.0 2.9e-05 24.0 3.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK61587.1 - 3.4e-05 23.6 8.0 3.4e-05 23.6 8.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK61587.1 - 8.4e-05 22.8 5.8 8.4e-05 22.8 5.8 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain RRM_1 PF00076.22 KIK61587.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KIK61587.1 - 0.0021 17.9 7.1 0.0021 17.9 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UBP_var PF17807.1 KIK61587.1 - 0.0084 15.8 0.8 0.017 14.8 0.8 1.5 1 0 0 1 1 1 1 Variant UBP zinc finger zf-RING_5 PF14634.6 KIK61587.1 - 0.016 15.2 6.7 0.016 15.2 6.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain TerY_C PF15616.6 KIK61587.1 - 0.016 15.3 0.7 0.016 15.3 0.7 2.7 3 0 0 3 3 3 0 TerY-C metal binding domain zf-ANAPC11 PF12861.7 KIK61587.1 - 0.016 15.2 4.0 0.035 14.2 4.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIK61587.1 - 0.086 12.6 6.5 0.2 11.5 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3584 PF12128.8 KIK61587.1 - 0.11 9.9 11.8 0.17 9.3 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2968 PF11180.8 KIK61587.1 - 0.18 11.4 11.7 0.082 12.5 5.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Macoilin PF09726.9 KIK61587.1 - 1.6 7.2 9.7 2.5 6.5 9.7 1.2 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 KIK61587.1 - 2.1 6.7 10.1 3 6.2 10.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF724 PF05266.14 KIK61587.1 - 2.6 7.9 11.7 4.3 7.1 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.6 KIK61587.1 - 3.6 6.9 17.6 6 6.2 17.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KIK61587.1 - 4.1 7.4 22.6 35 4.4 7.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 KIK61587.1 - 4.4 8.0 13.4 2.4 8.8 2.1 3.5 2 1 2 4 4 3 0 Bone marrow stromal antigen 2 Prok-RING_4 PF14447.6 KIK61587.1 - 5.1 7.0 21.8 0.86 9.5 10.5 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 MCU PF04678.13 KIK61587.1 - 7.4 6.6 9.1 2.7 8.1 5.9 1.8 1 1 1 2 2 2 0 Mitochondrial calcium uniporter SPX PF03105.19 KIK61587.1 - 9.8 6.0 11.6 18 5.1 11.6 1.7 1 1 0 1 1 1 0 SPX domain NUDIX PF00293.28 KIK61588.1 - 2.7e-11 43.6 0.0 4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Vma12 PF11712.8 KIK61589.1 - 4.4e-11 43.0 0.0 5.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5337 PF17272.2 KIK61589.1 - 0.036 13.9 0.5 0.055 13.3 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Cytochrome-c551 PF10643.9 KIK61589.1 - 0.099 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF2749 PF10907.8 KIK61589.1 - 0.12 12.5 2.1 0.16 12.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) DUF4231 PF14015.6 KIK61589.1 - 0.18 12.2 1.4 0.47 11.0 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Atx10homo_assoc PF09759.9 KIK61590.1 - 5.6e-24 84.0 0.0 1.6e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Leo1 PF04004.13 KIK61591.1 - 1.9e-49 167.7 0.4 1.9e-49 167.7 0.4 2.1 3 0 0 3 3 3 1 Leo1-like protein Cnd2 PF05786.14 KIK61593.1 - 9.2e-169 563.6 19.8 3.5e-168 561.7 19.8 1.7 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KIK61593.1 - 0.085 13.1 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Ribosomal_L7Ae PF01248.26 KIK61594.1 - 2.8e-22 78.3 0.0 3.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Actin PF00022.19 KIK61595.1 - 4.4e-40 137.5 0.0 5.7e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 Actin DNA_pol_B PF00136.21 KIK61596.1 - 9.7e-148 492.7 0.8 1.3e-147 492.2 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KIK61596.1 - 4.5e-87 292.3 0.0 1.7e-86 290.4 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KIK61596.1 - 1e-17 64.3 7.9 2.3e-17 63.2 7.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KIK61596.1 - 0.0022 16.9 1.1 0.0044 16.0 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KIK61596.1 - 0.0046 16.7 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-ACC PF17848.1 KIK61596.1 - 3.2 7.9 6.4 3 8.0 0.1 3.0 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain PMM PF03332.13 KIK61597.1 - 1.5e-105 351.8 0.6 1.8e-105 351.6 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KIK61597.1 - 0.0003 20.6 0.0 0.011 15.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KIK61597.1 - 0.0065 16.0 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HCBP_related PF06594.11 KIK61597.1 - 0.037 14.0 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain bVLRF1 PF18826.1 KIK61598.1 - 6.2e-68 227.4 0.0 2e-67 225.7 0.0 1.9 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_3 PF13606.6 KIK61598.1 - 0.019 15.5 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_aberr PF17017.5 KIK61599.1 - 1.1 9.3 6.5 2.5 8.2 3.2 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger DUF2457 PF10446.9 KIK61599.1 - 3.6 6.6 6.5 6.6 5.7 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAC3_GANP PF03399.16 KIK61600.1 - 7.4e-23 81.4 2.2 4.1e-21 75.6 2.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KIK61600.1 - 5.6e-07 29.6 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EF-hand_2 PF09068.11 KIK61600.1 - 7e-05 23.0 0.5 0.063 13.4 0.1 2.4 2 0 0 2 2 2 2 EF hand tRNA-synt_2 PF00152.20 KIK61601.1 - 2.8e-70 236.9 0.0 1e-68 231.8 0.0 2.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) LIM PF00412.22 KIK61602.1 - 2.7e-27 94.8 27.2 1e-11 44.9 9.4 4.2 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 KIK61602.1 - 0.39 10.3 15.0 1.4 8.6 3.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Iso_dh PF00180.20 KIK61603.1 - 6.1e-86 288.7 0.0 7.5e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 KIK61604.1 - 3e-20 72.5 40.6 1.4e-19 70.2 40.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK61604.1 - 2.9e-11 43.3 4.3 4.3e-11 42.7 4.3 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pre-SET PF05033.16 KIK61605.1 - 1.4e-20 73.9 6.4 3.7e-20 72.6 6.4 1.7 1 0 0 1 1 1 1 Pre-SET motif SET PF00856.28 KIK61605.1 - 2e-08 34.8 0.0 2e-08 34.8 0.0 2.7 2 1 0 2 2 2 1 SET domain DnaJ PF00226.31 KIK61606.1 - 3.9e-21 74.9 1.4 6.9e-21 74.1 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain Mlf1IP PF10248.9 KIK61606.1 - 0.011 15.7 0.5 0.02 14.8 0.5 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein HD_assoc PF13286.6 KIK61607.1 - 0.092 13.3 0.7 0.092 13.3 0.7 2.2 2 1 0 2 2 2 0 Phosphohydrolase-associated domain Nucleocap_ssRNA PF11128.8 KIK61607.1 - 0.11 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Raf1_N PF18578.1 KIK61607.1 - 0.22 12.0 7.7 0.89 10.1 0.5 2.6 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain Jnk-SapK_ap_N PF09744.9 KIK61607.1 - 8.2 6.6 35.5 0.17 12.1 11.6 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 F-box-like PF12937.7 KIK61608.1 - 3.1e-09 36.6 0.2 7.4e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK61608.1 - 0.00031 20.5 1.8 0.00055 19.7 0.1 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIK61608.1 - 0.089 13.2 0.7 19 5.8 1.4 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-CSL PF05207.13 KIK61609.1 - 3.1e-21 74.9 0.5 3.1e-21 74.9 0.5 1.6 2 0 0 2 2 2 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KIK61609.1 - 0.0023 18.0 0.7 0.0044 17.1 0.7 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Lar_restr_allev PF14354.6 KIK61609.1 - 0.048 14.1 0.1 0.073 13.5 0.1 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.6 KIK61609.1 - 0.1 12.5 0.6 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Tyr-DNA_phospho PF06087.12 KIK61610.1 - 8.8e-54 183.0 0.0 1.9e-53 181.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KIK61610.1 - 0.00038 20.2 8.6 0.0016 18.2 1.9 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 KIK61610.1 - 0.00063 19.6 0.3 0.021 14.7 0.4 2.8 2 1 0 2 2 2 1 PLD-like domain Myc_N PF01056.18 KIK61610.1 - 1.7 8.5 11.5 13 5.6 8.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region GATA PF00320.27 KIK61611.1 - 9.5e-26 89.1 20.3 5.1e-14 51.6 5.7 3.3 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIK61611.1 - 0.02 14.4 2.4 0.68 9.5 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding NMD3 PF04981.13 KIK61611.1 - 0.02 14.4 4.3 0.52 9.7 0.3 2.1 1 1 1 2 2 2 0 NMD3 family Cytochrom_c3_2 PF14537.6 KIK61611.1 - 0.035 14.6 5.8 0.57 10.7 6.4 2.2 1 1 1 2 2 2 0 Cytochrome c3 zf-RRPl_C4 PF17026.5 KIK61611.1 - 0.039 14.1 1.7 1.6 8.9 3.0 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type OrfB_Zn_ribbon PF07282.11 KIK61611.1 - 0.1 12.5 13.7 0.24 11.3 1.8 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KIK61611.1 - 0.18 11.7 7.3 2.4 8.1 0.7 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 KIK61611.1 - 0.22 11.6 9.3 6.1 6.9 1.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon ArfGap PF01412.18 KIK61611.1 - 0.25 11.4 3.0 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KIK61611.1 - 6.5 7.0 6.5 24 5.2 0.9 2.8 2 2 0 2 2 2 0 Zinc ribbon domain SHNi-TPR PF10516.9 KIK61614.1 - 8.1e-15 54.0 0.2 1.4e-12 46.9 0.0 2.6 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KIK61614.1 - 4e-11 43.0 5.5 4.5e-06 26.9 0.8 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK61614.1 - 1.2e-06 28.2 1.0 0.033 14.3 0.5 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK61614.1 - 7.2e-06 25.6 0.8 0.02 14.7 1.3 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK61614.1 - 0.00039 20.2 0.1 0.16 11.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK61614.1 - 0.0013 18.7 0.5 0.6 10.3 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK61614.1 - 0.0015 18.6 5.8 0.45 10.9 1.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK61614.1 - 0.012 15.2 4.5 8.4 6.2 4.3 4.0 3 1 0 3 3 3 0 TPR repeat MCPVI PF02993.14 KIK61614.1 - 0.013 15.3 1.3 0.022 14.6 1.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI TPR_19 PF14559.6 KIK61614.1 - 0.043 14.3 0.1 0.043 14.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK61614.1 - 0.2 11.7 3.0 0.98 9.5 1.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CAP_N PF01213.19 KIK61614.1 - 4.1 6.8 10.5 0.041 13.4 1.6 2.1 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) N terminal TPR_16 PF13432.6 KIK61614.1 - 5.6 7.7 16.1 0.059 14.0 2.2 4.6 5 1 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KIK61614.1 - 6.5 6.9 11.7 0.051 13.6 1.7 2.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain CFEM PF05730.11 KIK61615.1 - 2.5e-08 33.9 13.2 3.9e-08 33.3 13.2 1.3 1 0 0 1 1 1 1 CFEM domain DUF1180 PF06679.12 KIK61615.1 - 0.59 10.5 4.9 0.91 9.9 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ANTH PF07651.16 KIK61616.1 - 2.5e-51 174.3 0.0 3.4e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 KIK61616.1 - 0.0014 19.0 47.0 0.0014 19.0 47.0 9.9 1 1 5 6 6 6 1 Domain of unknown function (DUF1720) ENTH PF01417.20 KIK61616.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 ENTH domain adh_short PF00106.25 KIK61617.1 - 2.9e-36 124.7 0.0 4.7e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK61617.1 - 8.5e-26 90.9 0.0 5.8e-21 75.1 0.0 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK61617.1 - 1.4e-05 25.1 0.4 7.2e-05 22.8 0.0 2.2 3 0 0 3 3 3 1 KR domain DUF1776 PF08643.10 KIK61617.1 - 0.029 13.8 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ApbA PF02558.16 KIK61617.1 - 0.063 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KIK61617.1 - 0.18 11.2 0.1 0.78 9.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FGGY_C PF02782.16 KIK61618.1 - 7.1e-59 198.9 1.7 1.2e-58 198.2 1.7 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIK61618.1 - 3.7e-55 187.2 0.0 1.5e-53 181.9 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_hydro_47 PF01532.20 KIK61619.1 - 1.7e-132 442.6 0.0 2.2e-132 442.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PI-PLC-X PF00388.19 KIK61621.1 - 1.5e-55 186.8 0.0 2.6e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIK61621.1 - 8.1e-42 142.2 0.2 3.7e-41 140.1 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.6 KIK61621.1 - 1.7e-08 34.7 2.6 3.2e-07 30.7 0.5 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KIK61621.1 - 3.8e-06 26.0 0.3 0.15 11.7 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_like PF09279.11 KIK61621.1 - 8.1e-05 23.0 1.1 0.00017 22.0 1.1 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KIK61621.1 - 0.00019 21.7 0.0 0.0023 18.2 0.0 2.5 1 1 0 1 1 1 1 C2 domain EF-hand_8 PF13833.6 KIK61621.1 - 0.0005 19.9 0.4 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KIK61621.1 - 0.0008 19.2 0.6 0.35 10.9 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 KIK61621.1 - 0.0071 16.2 0.4 0.026 14.4 0.4 2.1 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 KIK61621.1 - 0.014 15.4 0.4 0.064 13.2 0.4 2.1 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PH_12 PF16457.5 KIK61621.1 - 0.15 12.6 2.7 0.18 12.3 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF647 PF04884.14 KIK61622.1 - 9.6e-72 241.5 0.9 1.3e-71 241.0 0.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis FHA PF00498.26 KIK61623.1 - 0.0012 19.1 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK61623.1 - 0.021 15.1 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Pes-10 PF07149.11 KIK61623.1 - 5.8 5.9 9.2 10 5.1 9.2 1.2 1 0 0 1 1 1 0 Pes-10 Aldedh PF00171.22 KIK61624.1 - 2.8e-12 45.9 5.3 1e-09 37.4 4.0 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 KIK61624.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) UBD PF16455.5 KIK61624.1 - 0.15 12.3 0.2 0.45 10.8 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-binding domain Unstab_antitox PF09720.10 KIK61624.1 - 0.16 12.1 0.8 0.37 10.9 0.8 1.6 1 0 0 1 1 1 0 Putative addiction module component CDC24 PF06395.11 KIK61625.1 - 8.6e-08 32.3 0.0 5.2e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.6 KIK61625.1 - 1.9e-06 28.2 0.0 4.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CH PF00307.31 KIK61625.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain ATP-synt_ab PF00006.25 KIK61628.1 - 2.7e-73 246.2 0.0 3.7e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KIK61628.1 - 1.5e-42 144.9 0.0 2.4e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KIK61628.1 - 9.8e-18 64.4 1.2 2.4e-17 63.2 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 KIK61629.1 - 1.9e-26 92.2 1.1 2.3e-26 92.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 KIK61629.1 - 0.059 13.4 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 UvrA interaction domain FF PF01846.19 KIK61630.1 - 7e-34 115.8 11.1 1e-12 48.0 0.1 5.9 5 0 0 5 5 5 5 FF domain WW PF00397.26 KIK61630.1 - 2.3e-11 43.6 17.5 5.5e-06 26.4 6.2 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KIK61630.1 - 0.0037 17.9 11.7 0.016 15.8 0.1 4.7 5 0 0 5 5 5 1 p190-A and -B Rho GAPs FF domain Tmemb_14 PF03647.13 KIK61631.1 - 8.7e-19 68.1 5.7 1e-18 67.9 5.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C stn_TNFRSF12A PF12191.8 KIK61632.1 - 0.0067 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Insulin_TMD PF17870.1 KIK61632.1 - 0.0097 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KIK61632.1 - 0.045 14.6 0.0 0.1 13.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 KIK61632.1 - 0.14 12.0 0.4 0.51 10.2 0.0 2.0 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Big_9 PF17963.1 KIK61632.1 - 5.5 7.8 9.7 2.5 8.9 3.4 2.9 2 1 1 3 3 3 0 Bacterial Ig domain TMEM154 PF15102.6 KIK61633.1 - 0.001 19.0 0.4 0.001 19.0 0.4 2.4 1 1 1 2 2 2 1 TMEM154 protein family Presenilin PF01080.17 KIK61633.1 - 0.003 16.4 1.0 0.0041 15.9 1.0 1.3 1 0 0 1 1 1 1 Presenilin SPX PF03105.19 KIK61633.1 - 0.0062 16.5 14.2 0.008 16.1 14.2 1.2 1 0 0 1 1 1 1 SPX domain RCR PF12273.8 KIK61633.1 - 0.0071 17.0 4.6 0.0076 16.9 0.0 2.5 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Apt1 PF10351.9 KIK61633.1 - 0.0074 15.2 8.7 0.01 14.7 8.7 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Insulin_TMD PF17870.1 KIK61633.1 - 0.049 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Podoplanin PF05808.11 KIK61633.1 - 4.7 7.3 6.4 10 6.2 6.1 1.8 1 1 0 1 1 1 0 Podoplanin DUF2408 PF10303.9 KIK61634.1 - 1.3e-63 213.6 6.7 2.2e-42 144.8 0.0 5.2 5 0 0 5 5 5 4 Protein of unknown function (DUF2408) Laminin_II PF06009.12 KIK61634.1 - 0.00052 20.0 6.4 0.03 14.3 0.7 3.9 4 0 0 4 4 4 1 Laminin Domain II Laminin_I PF06008.14 KIK61634.1 - 0.0029 17.3 0.6 0.059 13.1 0.1 2.3 1 1 0 2 2 2 1 Laminin Domain I Lebercilin PF15619.6 KIK61634.1 - 0.0048 16.6 3.6 0.011 15.4 2.3 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease N1221 PF07923.13 KIK61634.1 - 0.0085 15.3 0.2 0.017 14.3 0.2 1.5 1 0 0 1 1 1 1 N1221-like protein FH2 PF02181.23 KIK61634.1 - 0.015 14.4 0.2 0.074 12.2 0.3 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain APG17 PF04108.12 KIK61634.1 - 0.021 14.0 6.3 0.053 12.6 0.8 2.7 1 1 2 3 3 3 0 Autophagy protein Apg17 PriC PF07445.12 KIK61634.1 - 0.05 13.5 1.8 0.16 11.9 1.8 1.8 1 1 0 1 1 1 0 Primosomal replication protein priC Fez1 PF06818.15 KIK61634.1 - 0.098 13.1 0.7 0.28 11.6 0.7 1.8 1 0 0 1 1 1 0 Fez1 ZapA PF05164.13 KIK61634.1 - 0.12 12.9 0.6 1.6 9.2 0.0 2.9 2 1 0 2 2 2 0 Cell division protein ZapA GrpE PF01025.19 KIK61634.1 - 0.12 12.1 0.8 0.47 10.1 0.3 2.3 3 0 0 3 3 3 0 GrpE Caprin-1_dimer PF18293.1 KIK61634.1 - 0.14 12.6 1.1 0.3 11.6 0.1 2.1 2 0 0 2 2 2 0 Caprin-1 dimerization domain NPV_P10 PF05531.12 KIK61634.1 - 0.33 11.5 4.9 10 6.6 0.3 4.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KIK61634.1 - 0.4 10.2 5.1 0.29 10.7 1.4 2.5 1 1 2 3 3 3 0 Intermediate filament protein Med9 PF07544.13 KIK61634.1 - 0.43 10.7 4.9 2.2 8.4 0.0 4.0 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 HAP1_N PF04849.13 KIK61634.1 - 0.59 9.3 7.7 3.2 6.9 0.2 3.1 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF4201 PF13870.6 KIK61634.1 - 2 8.1 8.5 7 6.3 2.9 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) LMP PF04778.12 KIK61634.1 - 2.2 8.2 5.8 0.38 10.7 0.7 2.2 3 0 0 3 3 2 0 LMP repeated region ATG16 PF08614.11 KIK61634.1 - 3.1 8.0 6.8 2.7 8.2 3.9 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CorA PF01544.18 KIK61634.1 - 3.8 6.7 8.8 0.38 10.0 1.3 2.6 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein BLOC1_2 PF10046.9 KIK61634.1 - 7.1 7.0 7.5 5.5 7.4 0.8 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KIK61635.1 - 2e-45 154.5 31.7 2.3e-45 154.3 31.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KIK61635.1 - 2.2e-10 40.4 31.5 0.00038 19.9 2.3 3.1 1 1 2 3 3 3 3 Tropomyosin DHR10 PF18595.1 KIK61635.1 - 0.0002 21.4 36.2 0.0093 16.0 11.4 2.6 2 1 0 2 2 2 2 Designed helical repeat protein 10 domain KELK PF15796.5 KIK61635.1 - 0.0005 20.5 8.1 0.0005 20.5 8.1 3.6 2 2 2 4 4 4 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Uso1_p115_C PF04871.13 KIK61635.1 - 0.0011 19.3 14.7 0.0011 19.3 14.7 2.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region HrpB7 PF09486.10 KIK61635.1 - 0.0062 16.9 20.1 0.057 13.8 7.8 2.2 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 KIK61635.1 - 0.0069 15.8 32.9 0.018 14.4 14.2 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KIK61635.1 - 0.02 14.4 30.8 0.024 14.1 30.8 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cep57_CLD_2 PF14197.6 KIK61635.1 - 0.05 13.7 2.4 0.05 13.7 2.4 4.2 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 TAFH PF07531.14 KIK61635.1 - 0.055 13.6 0.8 0.055 13.6 0.8 2.4 2 0 0 2 2 2 0 NHR1 homology to TAF FliD_C PF07195.12 KIK61635.1 - 0.1 12.0 16.4 0.15 11.5 7.3 2.5 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Jnk-SapK_ap_N PF09744.9 KIK61635.1 - 0.1 12.8 32.6 0.076 13.2 15.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KIK61635.1 - 0.13 12.3 15.3 0.051 13.6 7.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KIK61635.1 - 0.15 12.5 32.6 0.11 12.8 16.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 KIK61635.1 - 0.15 12.6 38.0 0.2 12.2 22.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KIK61635.1 - 0.19 11.9 33.4 0.38 11.0 15.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DLP_helical PF18709.1 KIK61635.1 - 0.23 10.6 16.5 0.41 9.8 16.5 1.5 1 1 0 1 1 1 0 Dynamin-like helical domain FPP PF05911.11 KIK61635.1 - 0.31 9.2 27.0 0.36 9.0 27.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil ERM PF00769.19 KIK61635.1 - 0.48 10.2 34.5 0.74 9.6 31.2 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Flagellin_C PF00700.21 KIK61635.1 - 0.51 10.7 5.4 0.95 9.9 0.8 2.7 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region EzrA PF06160.12 KIK61635.1 - 0.54 8.4 23.5 0.085 11.0 11.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HGD-D PF06050.13 KIK61635.1 - 0.56 9.9 4.0 0.34 10.6 2.2 1.5 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Lectin_N PF03954.14 KIK61635.1 - 0.57 9.9 13.4 0.4 10.4 2.9 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain KMP11 PF03037.16 KIK61635.1 - 0.59 10.9 8.8 0.28 12.0 4.4 2.3 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 T3SSipB PF16535.5 KIK61635.1 - 0.7 10.4 18.1 0.3 11.6 7.4 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB HOOK PF05622.12 KIK61635.1 - 0.8 7.8 28.7 0.91 7.6 28.7 1.0 1 0 0 1 1 1 0 HOOK protein HetR_C PF18460.1 KIK61635.1 - 0.87 9.6 9.3 7.8 6.5 0.3 2.8 1 1 2 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Fez1 PF06818.15 KIK61635.1 - 0.91 9.9 27.8 3.7 8.0 27.8 1.8 1 1 0 1 1 1 0 Fez1 TMF_DNA_bd PF12329.8 KIK61635.1 - 0.92 9.5 32.3 4.3 7.4 11.7 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KIK61635.1 - 0.94 8.3 32.4 0.85 8.4 15.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KIK61635.1 - 0.96 9.5 18.1 3 8.0 2.0 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CREPT PF16566.5 KIK61635.1 - 1.2 9.3 22.7 2.2 8.4 7.0 2.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BRE1 PF08647.11 KIK61635.1 - 1.2 9.3 28.4 0.16 12.1 12.1 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 KIK61635.1 - 1.2 8.7 31.7 1.1 8.9 28.8 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HisKA_3 PF07730.13 KIK61635.1 - 1.4 9.5 10.8 16 6.1 0.3 3.3 1 1 1 2 2 2 0 Histidine kinase PI3K_P85_iSH2 PF16454.5 KIK61635.1 - 1.4 8.5 25.1 0.65 9.6 6.4 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Laminin_II PF06009.12 KIK61635.1 - 1.5 8.8 19.2 0.19 11.8 4.7 2.6 1 1 1 2 2 2 0 Laminin Domain II DASH_Spc19 PF08287.11 KIK61635.1 - 1.6 8.6 23.4 2.7 7.9 7.6 2.5 1 1 1 2 2 2 0 Spc19 DUF2408 PF10303.9 KIK61635.1 - 2.1 8.9 22.0 1.5 9.4 8.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF3584 PF12128.8 KIK61635.1 - 2.2 5.7 28.0 1.2 6.5 13.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Aconitase_C PF00694.19 KIK61635.1 - 2.9 8.2 6.7 0.54 10.6 2.1 1.9 2 0 0 2 2 2 0 Aconitase C-terminal domain ADIP PF11559.8 KIK61635.1 - 3.1 7.9 31.1 3 7.9 5.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIK61635.1 - 3.3 7.0 22.1 12 5.2 22.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.18 KIK61635.1 - 3.4 7.4 24.8 2.8 7.7 10.2 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein CHDCT2 PF08074.11 KIK61635.1 - 3.7 7.7 11.1 4.6 7.4 4.7 2.2 1 1 0 2 2 2 0 CHDCT2 (NUC038) domain Csm1_N PF18504.1 KIK61635.1 - 3.7 7.9 27.6 3.2 8.1 8.0 3.7 1 1 2 3 3 3 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 KIK61635.1 - 4 7.4 34.9 41 4.2 12.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 KIK61635.1 - 4.1 7.7 28.1 7.1 6.9 4.1 4.1 1 1 4 5 5 5 0 Haemolysin XhlA CLZ PF16526.5 KIK61635.1 - 4.1 7.8 27.3 6.5 7.2 6.9 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 KIK61635.1 - 6 5.3 7.1 6.5 5.2 7.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 KIK61635.1 - 6.8 7.0 32.0 4.4 7.6 17.8 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Sec34 PF04136.15 KIK61635.1 - 7.2 6.5 14.4 0.93 9.4 5.4 2.3 2 1 0 2 2 2 0 Sec34-like family TMF_TATA_bd PF12325.8 KIK61635.1 - 7.7 6.8 28.4 7.4 6.8 11.6 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HHV-5_US34A PF17087.5 KIK61635.1 - 8.1 6.7 8.5 0.56 10.4 2.2 2.2 2 1 0 2 2 2 0 Herpesvirus US34A protein family She9_MDM33 PF05546.11 KIK61635.1 - 8.6 6.1 22.7 0.45 10.3 5.4 3.1 1 1 2 3 3 3 0 She9 / Mdm33 family Syntaxin_2 PF14523.6 KIK61635.1 - 8.6 6.8 19.5 0.42 11.0 11.0 2.2 1 1 1 2 2 2 0 Syntaxin-like protein TPR_MLP1_2 PF07926.12 KIK61635.1 - 9.1 6.4 35.8 15 5.7 12.1 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC53 PF10152.9 KIK61635.1 - 9.9 6.6 12.5 1.9e+02 2.4 11.9 2.2 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex SelR PF01641.18 KIK61636.1 - 2.6e-52 176.0 0.1 2.9e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 KIK61636.1 - 0.0067 16.5 1.4 0.099 12.8 0.4 2.8 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 ADD_ATRX PF17981.1 KIK61636.1 - 0.11 12.3 0.0 0.8 9.6 0.0 2.0 2 0 0 2 2 2 0 Cysteine Rich ADD domain DZR PF12773.7 KIK61636.1 - 0.13 12.3 2.5 3.9 7.6 0.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-ACC PF17848.1 KIK61636.1 - 0.16 12.1 1.2 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain IF4E PF01652.18 KIK61637.1 - 3.3e-50 170.0 0.0 4.6e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kei1 PF08552.11 KIK61638.1 - 8.6e-52 175.8 5.7 1.5e-51 175.0 5.7 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 CAF20 PF17052.5 KIK61639.1 - 8 6.6 6.6 3.2 7.9 2.6 2.2 2 0 0 2 2 2 0 Cap associated factor Brix PF04427.18 KIK61640.1 - 1.7e-25 90.3 0.0 2.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain Med4 PF10018.9 KIK61641.1 - 4.2e-22 78.8 0.1 5.9e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CENP-H PF05837.12 KIK61641.1 - 0.0082 16.5 2.6 0.013 15.9 2.6 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Muted PF14942.6 KIK61641.1 - 0.021 15.2 0.7 0.028 14.8 0.7 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Herpes_UL25 PF01499.16 KIK61641.1 - 0.14 10.7 0.2 0.17 10.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family HAUS6_N PF14661.6 KIK61641.1 - 0.19 11.3 1.0 0.32 10.5 1.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MMS19_C PF12460.8 KIK61642.1 - 6.4e-115 384.6 0.5 1e-113 380.6 0.0 2.4 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KIK61642.1 - 1.6e-98 329.5 0.6 4.5e-95 318.2 0.0 3.7 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KIK61642.1 - 1.5e-05 25.3 2.7 3.5 8.1 0.0 5.3 4 2 1 5 5 5 3 HEAT repeats Neurochondrin PF05536.11 KIK61642.1 - 0.015 13.7 1.4 3.2 6.0 0.2 3.7 3 1 0 3 3 3 0 Neurochondrin GIT_SHD PF08518.11 KIK61642.1 - 0.14 11.8 1.4 0.29 10.8 1.4 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT FAM150 PF15129.6 KIK61643.1 - 0.17 12.1 0.2 0.41 10.8 0.2 1.6 1 0 0 1 1 1 0 FAM150 family GFO_IDH_MocA PF01408.22 KIK61644.1 - 6.7e-21 75.3 0.0 1.1e-20 74.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK61644.1 - 0.00034 20.6 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DXP_reductoisom PF02670.16 KIK61644.1 - 0.035 14.8 0.0 0.061 14.0 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KIK61644.1 - 0.095 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DPBB_1 PF03330.18 KIK61646.1 - 0.00017 21.8 0.7 0.00017 21.8 0.7 2.3 2 1 0 2 2 2 1 Lytic transglycolase DPBB_1 PF03330.18 KIK61647.1 - 0.0035 17.6 0.5 0.0079 16.5 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase DSPc PF00782.20 KIK61648.1 - 1.1e-24 86.7 0.0 1.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KIK61648.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KIK61648.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2492 PF10678.9 KIK61648.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) Peptidase_A17 PF05380.13 KIK61648.1 - 0.16 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase CRAL_TRIO PF00650.20 KIK61649.1 - 5.2e-29 101.0 0.0 7.7e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK61649.1 - 2.7e-05 24.3 0.0 7.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPT PF03151.16 KIK61651.1 - 8.1e-57 192.8 20.7 9.9e-57 192.5 20.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KIK61651.1 - 1.4e-11 44.1 21.6 1.8e-11 43.8 21.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIK61651.1 - 8.3e-11 42.2 34.2 3.1e-07 30.6 13.6 2.7 2 1 0 2 2 2 2 EamA-like transporter family HEAT PF02985.22 KIK61652.1 - 0.15 12.4 11.9 20 5.8 0.0 8.2 9 0 0 9 9 9 0 HEAT repeat Ribosomal_S4e PF00900.20 KIK61653.1 - 1e-35 121.4 0.1 2.3e-35 120.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KIK61653.1 - 3e-25 87.6 0.2 5.3e-25 86.8 0.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KIK61653.1 - 3.2e-21 75.1 5.8 7.9e-21 73.9 5.8 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KIK61653.1 - 2.3e-09 36.8 0.2 6.5e-09 35.4 0.0 1.9 3 0 0 3 3 3 1 S4 domain KOW PF00467.29 KIK61653.1 - 1.3e-05 25.0 1.8 1.3e-05 25.0 1.8 2.2 2 0 0 2 2 2 1 KOW motif Sec63 PF02889.16 KIK61654.1 - 5.4e-23 81.5 0.1 1.3e-22 80.3 0.0 1.6 2 0 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.31 KIK61654.1 - 4.6e-15 55.5 0.4 1.2e-14 54.1 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain LEM PF03020.15 KIK61654.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 LEM domain DUF3107 PF11305.8 KIK61654.1 - 0.078 13.2 0.1 17 5.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3107) Paf1 PF03985.13 KIK61655.1 - 3e-65 220.9 0.6 4.6e-65 220.3 0.6 1.2 1 0 0 1 1 1 1 Paf1 TPR_2 PF07719.17 KIK61655.1 - 1.5e-06 27.9 4.3 0.035 14.2 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK61655.1 - 2.4e-05 23.9 0.3 2.5 8.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK61655.1 - 0.0038 17.5 0.0 8.7 7.0 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK61655.1 - 0.0058 17.1 0.0 21 5.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK61655.1 - 0.008 16.3 0.1 15 6.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK61655.1 - 0.016 15.5 0.2 2.3 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4494 PF14902.6 KIK61655.1 - 0.1 12.4 1.4 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4494) WD40 PF00400.32 KIK61656.1 - 1.9e-08 34.8 2.1 0.13 13.1 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat CPSF_A PF03178.15 KIK61656.1 - 0.1 11.9 0.0 0.64 9.3 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region Nup160 PF11715.8 KIK61656.1 - 0.1 11.2 0.0 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ZZ PF00569.17 KIK61657.1 - 1.3e-15 57.0 51.9 5.8e-07 29.2 2.4 6.2 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 KIK61657.1 - 9e-09 35.2 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KIK61657.1 - 0.018 15.3 51.5 0.031 14.6 2.0 5.7 4 1 1 5 5 5 0 C1 domain Yippee-Mis18 PF03226.14 KIK61657.1 - 0.17 12.1 0.1 0.17 12.1 0.1 4.4 3 1 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Synapsin_N PF10581.9 KIK61657.1 - 5 7.1 6.3 60 3.7 0.2 3.5 3 0 0 3 3 3 0 Synapsin N-terminal ZZ PF00569.17 KIK61658.1 - 1.9e-10 40.3 38.4 2.8e-07 30.2 2.8 5.2 5 1 0 5 5 5 3 Zinc finger, ZZ type C1_2 PF03107.16 KIK61658.1 - 6.2e-05 23.2 33.1 0.03 14.7 0.1 5.3 3 1 1 4 4 4 3 C1 domain PB1 PF00564.24 KIK61658.1 - 0.0023 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DZR PF12773.7 KIK61658.1 - 0.35 10.9 34.1 0.14 12.2 0.5 5.7 4 2 0 4 4 4 0 Double zinc ribbon AAA_5 PF07728.14 KIK61659.1 - 3e-61 205.4 0.0 1e-27 96.8 0.0 3.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK61659.1 - 0.067 13.6 0.6 13 6.1 0.0 4.1 4 1 1 5 5 5 0 AAA ATPase domain Mg_chelatase PF01078.21 KIK61659.1 - 0.12 11.8 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PHF5 PF03660.14 KIK61660.1 - 1.9e-52 175.9 7.9 2.1e-52 175.7 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KIK61660.1 - 0.038 11.9 4.8 0.042 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KIK61660.1 - 0.42 10.7 15.0 1.6 8.8 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KIK61660.1 - 2 8.8 17.7 0.37 11.1 2.7 2.6 1 1 1 2 2 2 0 C1 domain Voltage_CLC PF00654.20 KIK61661.1 - 9.5e-83 278.4 29.0 9.5e-83 278.4 29.0 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel Methyltransf_28 PF02636.17 KIK61662.1 - 1.4e-39 136.3 0.0 2.1e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KIK61662.1 - 2.3e-05 23.6 0.0 0.00016 20.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KIK61662.1 - 2.7e-05 24.8 0.0 0.0078 16.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61662.1 - 0.0049 17.5 0.0 0.048 14.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_33 PF10017.9 KIK61662.1 - 0.006 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent PRMT5 PF05185.16 KIK61662.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase NepR PF18557.1 KIK61662.1 - 0.087 12.5 0.2 17 5.2 0.2 2.7 2 0 0 2 2 2 0 Anti-sigma factor NepR FANCI_HD2 PF14680.6 KIK61662.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 Methyltransf_25 PF13649.6 KIK61663.1 - 1.4e-12 48.2 0.0 4.3e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61663.1 - 1.2e-10 41.9 0.0 2.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61663.1 - 9.1e-08 32.0 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIK61663.1 - 0.026 13.9 0.0 0.052 13.0 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB MTS PF05175.14 KIK61663.1 - 0.068 12.7 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_L37ae PF01780.19 KIK61664.1 - 1.1e-42 144.0 9.1 1.2e-42 143.8 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KIK61664.1 - 0.00037 20.4 2.4 0.00062 19.7 2.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KIK61664.1 - 0.0037 16.6 1.5 0.52 9.8 0.0 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Elf1 PF05129.13 KIK61664.1 - 0.0073 16.3 1.6 0.011 15.7 1.6 1.4 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 KIK61664.1 - 0.013 15.9 0.2 0.02 15.3 0.2 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_13 PF17977.1 KIK61664.1 - 0.016 15.3 1.5 0.023 14.8 1.5 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-BED PF02892.15 KIK61664.1 - 0.066 13.2 3.6 0.77 9.8 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 KIK61664.1 - 0.077 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIK61664.1 - 0.36 11.3 6.1 0.36 11.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 KIK61664.1 - 0.37 10.9 5.6 1.8 8.7 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger adh_short PF00106.25 KIK61665.1 - 9.6e-22 77.4 0.0 8.4e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK61665.1 - 3.2e-13 49.8 0.0 4.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK61665.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KIK61665.1 - 0.0062 16.6 0.1 0.041 13.9 0.1 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KIK61666.1 - 1.8e-26 92.8 0.1 2.6e-25 89.0 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK61666.1 - 2.2e-16 60.1 0.1 4.9e-16 59.0 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK61666.1 - 2.9e-07 30.6 0.1 4.4e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KIK61666.1 - 0.00024 21.2 0.4 0.00054 20.0 0.4 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KIK61666.1 - 0.00083 18.6 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DRMBL PF07522.14 KIK61667.1 - 2.6e-31 108.1 0.0 4.8e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KIK61667.1 - 1.6e-06 27.8 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK61667.1 - 0.12 12.4 0.8 0.24 11.4 0.8 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Glyco_hydro_47 PF01532.20 KIK61668.1 - 2.8e-133 445.2 0.0 4.1e-133 444.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.13 KIK61669.1 - 2.8e-28 98.3 0.2 5.1e-28 97.5 0.0 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Pkinase PF00069.25 KIK61670.1 - 2.7e-74 249.9 0.0 3.2e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61670.1 - 5.3e-32 111.1 0.0 2e-31 109.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KIK61670.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK61670.1 - 0.032 13.2 0.0 0.4 9.6 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIK61670.1 - 0.036 13.4 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like zf-RanBP PF00641.18 KIK61671.1 - 3.4e-13 48.6 24.3 0.00017 20.9 3.5 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KIK61671.1 - 0.074 13.1 9.0 5.9 7.0 0.1 4.8 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger DZR PF12773.7 KIK61671.1 - 3.2 7.8 16.4 6.8 6.8 7.8 2.8 1 1 1 2 2 2 0 Double zinc ribbon PHD_2 PF13831.6 KIK61671.1 - 6.2 6.5 5.7 28 4.4 0.1 3.3 3 0 0 3 3 3 0 PHD-finger NADH-u_ox-rdase PF10785.9 KIK61672.1 - 3.4e-31 107.8 5.1 5.2e-30 104.0 5.1 2.1 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KIK61672.1 - 7.2e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TOBE PF03459.17 KIK61674.1 - 0.098 13.0 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 TOBE domain MFS_1 PF07690.16 KIK61675.1 - 3.4e-28 98.6 48.8 1.1e-24 87.0 39.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK61675.1 - 0.017 14.4 28.0 0.15 11.3 27.2 2.4 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KIK61677.1 - 5.7e-28 97.8 50.9 6.2e-24 84.6 41.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK61677.1 - 0.019 14.3 30.8 0.058 12.7 26.6 2.6 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB HECT PF00632.25 KIK61678.1 - 2e-80 270.6 0.0 2.9e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KIK61678.1 - 0.015 15.3 2.3 0.55 10.4 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Nse4-Nse3_bdg PF15412.6 KIK61678.1 - 0.016 15.3 0.6 0.11 12.6 0.4 2.6 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE UIM PF02809.20 KIK61678.1 - 0.33 11.0 1.6 1.5 8.9 1.6 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif Aminotran_3 PF00202.21 KIK61679.1 - 4.9e-79 265.9 0.0 6.1e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III C_GCAxxG_C_C PF09719.10 KIK61679.1 - 0.28 11.5 5.8 1.9 8.8 0.1 3.3 1 1 2 3 3 3 0 Putative redox-active protein (C_GCAxxG_C_C) PRP1_N PF06424.12 KIK61680.1 - 1.9e-49 167.9 4.7 1.9e-49 167.9 4.7 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KIK61680.1 - 1.4e-30 103.3 27.4 0.00072 20.2 0.2 14.1 4 3 10 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.6 KIK61680.1 - 9.5e-22 77.3 12.8 0.0092 16.5 0.1 8.7 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIK61680.1 - 5.5e-14 52.5 10.5 1.4e-05 25.6 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK61680.1 - 6.9e-08 32.0 5.1 7.3 7.0 0.0 8.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK61680.1 - 1.2e-05 25.3 2.7 0.13 12.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK61680.1 - 3.9e-05 23.7 0.9 18 6.0 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK61680.1 - 0.00037 20.9 9.2 6.7 7.6 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK61680.1 - 0.00063 19.7 4.7 13 6.3 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.8 KIK61680.1 - 0.0018 17.3 9.5 0.16 10.9 0.1 4.3 4 1 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KIK61680.1 - 0.0049 16.6 0.5 33 4.5 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK61680.1 - 0.023 14.4 0.4 3.3 7.5 0.1 4.5 6 0 0 6 6 6 0 TPR repeat TPR_12 PF13424.6 KIK61680.1 - 0.048 14.0 12.0 6.8 7.1 0.1 6.1 5 2 0 6 6 6 0 Tetratricopeptide repeat Thioredoxin_3 PF13192.6 KIK61680.1 - 0.23 11.5 0.6 6.6 6.9 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin domain GNAT_acetyltr_2 PF13718.6 KIK61681.1 - 1.3e-85 286.4 0.0 2.6e-85 285.4 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KIK61681.1 - 1.7e-63 214.5 0.1 3.3e-63 213.5 0.1 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KIK61681.1 - 2.9e-55 186.9 0.0 1.2e-54 184.9 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KIK61681.1 - 3.8e-33 113.3 0.0 8.9e-33 112.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) dsrm PF00035.26 KIK61682.1 - 3e-07 31.0 0.0 3.3e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif CNH PF00780.22 KIK61684.1 - 1.9e-75 254.0 0.0 3.2e-75 253.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KIK61684.1 - 7.2e-35 120.9 0.0 1.2e-34 120.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KIK61684.1 - 2.5e-33 115.0 0.1 6.5e-33 113.7 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIK61684.1 - 1.7e-14 53.6 0.1 3.5e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KIK61684.1 - 0.0057 16.5 0.1 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain SecA_DEAD PF07517.14 KIK61684.1 - 0.065 12.5 0.1 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain Polysacc_deac_1 PF01522.21 KIK61685.1 - 5.4e-30 103.8 0.0 9.7e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIK61685.1 - 0.0064 15.7 0.0 0.013 14.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Carn_acyltransf PF00755.20 KIK61686.1 - 3.3e-172 574.2 0.0 3.9e-172 573.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sec1 PF00995.23 KIK61687.1 - 4.3e-125 419.2 0.0 5.1e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.29 KIK61688.1 - 1.5e-42 145.2 0.0 2.5e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK61688.1 - 3.3e-14 52.4 0.2 6.9e-14 51.4 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KIK61688.1 - 1.9e-10 40.5 1.0 2.9e-10 40.0 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KIK61688.1 - 1.4e-07 32.0 0.0 8.8e-05 22.9 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KIK61688.1 - 2.5e-07 30.8 0.2 2.9e-06 27.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK61688.1 - 9.3e-06 25.9 0.0 3.2e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KIK61688.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK61688.1 - 9e-05 22.8 0.1 0.0047 17.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KIK61688.1 - 0.0012 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 KIK61688.1 - 0.0017 18.0 0.1 0.0064 16.1 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KIK61688.1 - 0.0018 18.8 0.0 0.0079 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIK61688.1 - 0.0034 16.8 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KIK61688.1 - 0.0038 17.2 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KIK61688.1 - 0.0044 16.8 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK61688.1 - 0.0045 17.4 0.0 0.0086 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KIK61688.1 - 0.0057 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIK61688.1 - 0.0067 16.6 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK61688.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KIK61688.1 - 0.0078 16.0 0.2 0.048 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF4200 PF13863.6 KIK61688.1 - 0.012 16.0 1.8 0.029 14.8 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Sigma54_activat PF00158.26 KIK61688.1 - 0.014 15.1 0.0 0.047 13.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIK61688.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK61688.1 - 0.018 14.5 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 KIK61688.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK61688.1 - 0.021 15.3 1.0 12 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK61688.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIK61688.1 - 0.025 14.2 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 KIK61688.1 - 0.026 14.8 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK61688.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 KIK61688.1 - 0.048 13.0 1.0 0.17 11.2 0.0 2.3 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 KIK61688.1 - 0.062 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIK61688.1 - 0.062 12.9 0.4 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KIK61688.1 - 0.073 12.9 1.5 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK61688.1 - 0.08 12.2 0.6 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KIK61688.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_S10 PF00450.22 KIK61689.1 - 3.8e-63 214.3 0.0 4.2e-62 210.9 0.0 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase GCFC PF07842.12 KIK61690.1 - 2.6e-78 263.4 8.0 3.6e-78 263.0 8.0 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KIK61690.1 - 3.3e-15 56.3 9.2 3.3e-15 56.3 9.2 2.5 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KIK61690.1 - 2.7e-14 52.7 1.2 5.9e-14 51.7 1.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIK61690.1 - 1.7e-07 31.2 1.7 8.3e-07 29.0 1.7 2.2 1 0 0 1 1 1 1 G-patch domain CRAL_TRIO_2 PF13716.6 KIK61692.1 - 1.1e-29 103.3 1.2 1.5e-29 102.9 0.3 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KIK61692.1 - 2.5e-29 102.1 0.0 4.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 KIK61692.1 - 5.3e-05 23.0 0.2 0.00029 20.6 0.2 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain TgMIC1 PF11476.8 KIK61692.1 - 0.0052 16.5 0.6 0.011 15.5 0.6 1.4 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 AMP-binding PF00501.28 KIK61693.1 - 5e-73 246.1 0.0 6.8e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK61693.1 - 2.3e-06 28.5 0.2 7.3e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HCNGP PF07818.13 KIK61694.1 - 4.3e-24 85.0 0.2 8.6e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 HCNGP-like protein TMEM51 PF15345.6 KIK61695.1 - 0.079 12.8 0.8 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 TMEM154 PF15102.6 KIK61695.1 - 0.13 12.1 0.6 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 KIK61695.1 - 0.27 12.2 0.0 0.27 12.2 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cyto_heme_lyase PF01265.17 KIK61696.1 - 2.4e-83 280.1 11.3 3.1e-82 276.4 11.3 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Pro_isomerase PF00160.21 KIK61697.1 - 4.9e-26 91.9 0.0 6.8e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans PF04082.18 KIK61699.1 - 5e-05 22.5 0.1 9.3e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK61699.1 - 0.4 10.9 3.8 0.86 9.8 3.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.29 KIK61700.1 - 3.7e-07 30.6 0.0 1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Atg14 PF10186.9 KIK61701.1 - 5.8e-42 143.9 0.0 9.9e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Herpes_UL6 PF01763.16 KIK61701.1 - 0.0057 15.2 0.0 0.0078 14.8 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like THOC7 PF05615.13 KIK61701.1 - 0.0081 16.4 1.3 0.015 15.6 1.3 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 YscO PF07321.12 KIK61701.1 - 0.015 15.3 2.6 0.024 14.6 2.6 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO APG6_N PF17675.1 KIK61701.1 - 0.049 14.2 0.5 0.089 13.3 0.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region EzrA PF06160.12 KIK61701.1 - 0.051 11.8 0.3 0.072 11.3 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Prominin PF05478.11 KIK61701.1 - 0.15 10.0 0.6 0.23 9.4 0.6 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 KIK61701.1 - 0.19 9.2 3.7 0.27 8.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 KIK61701.1 - 0.26 11.5 8.1 0.038 14.2 3.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KIK61701.1 - 0.3 11.1 3.7 0.55 10.3 3.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-UBR PF02207.20 KIK61701.1 - 0.31 11.2 1.8 0.52 10.5 1.8 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Spc7 PF08317.11 KIK61701.1 - 0.33 9.8 2.7 2.5 6.9 1.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Thiolase_N PF00108.23 KIK61702.1 - 2.6e-74 249.9 0.4 5.3e-74 248.9 0.4 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK61702.1 - 2.5e-42 143.4 0.4 4.8e-42 142.5 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK61702.1 - 1.5e-05 24.8 1.5 8.1e-05 22.3 0.7 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK61702.1 - 0.021 14.7 0.9 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Egh16-like PF11327.8 KIK61703.1 - 5.4e-43 147.5 0.4 6.5e-43 147.3 0.4 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor FlaC_arch PF05377.11 KIK61705.1 - 0.0037 17.6 2.0 0.0037 17.6 2.0 3.4 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Nsp1 PF11501.8 KIK61705.1 - 0.016 15.3 0.3 0.057 13.5 0.0 2.1 2 0 0 2 2 2 0 Non structural protein Nsp1 FlgM PF04316.13 KIK61705.1 - 0.084 13.2 3.9 0.1 13.0 1.0 2.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM tRNA-synt_1e PF01406.19 KIK61705.1 - 0.16 11.3 5.3 0.27 10.6 5.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Nup54 PF13874.6 KIK61705.1 - 0.24 11.5 15.7 0.059 13.5 11.2 2.2 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 KIK61705.1 - 1.2 9.2 11.9 1.3 9.1 6.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cep57_CLD PF14073.6 KIK61705.1 - 2.2 8.2 19.3 3.4 7.7 18.9 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF4162 PF13732.6 KIK61705.1 - 3.5 8.4 8.6 4.7 8.0 1.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4162) DUF5320 PF17253.2 KIK61705.1 - 4.1 8.5 4.9 1.3 10.2 1.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) PH PF00169.29 KIK61706.1 - 1.2e-14 54.7 0.0 1.8e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KIK61706.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KIK61706.1 - 0.025 14.9 0.1 2.2 8.7 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Flg_new PF09479.10 KIK61706.1 - 0.24 11.6 1.4 10 6.4 0.1 2.4 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Herpes_MCP PF03122.14 KIK61706.1 - 0.25 8.7 0.0 0.28 8.6 0.0 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein Pkinase_Tyr PF07714.17 KIK61707.1 - 6.3e-31 107.6 0.0 8.7e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK61707.1 - 1.2e-28 100.3 0.0 2.3e-28 99.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KIK61707.1 - 0.0014 18.6 1.5 0.0028 17.6 0.8 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK61707.1 - 0.0019 17.6 0.8 0.0035 16.7 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK61707.1 - 0.0023 17.6 0.1 0.0046 16.6 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIK61707.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DnaJ-X PF14308.6 KIK61709.1 - 7.3e-62 208.5 0.7 7.3e-62 208.5 0.7 2.5 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIK61709.1 - 6.6e-25 87.0 1.8 6.6e-25 87.0 1.8 2.4 2 0 0 2 2 2 1 DnaJ domain DUF3450 PF11932.8 KIK61709.1 - 0.11 11.8 9.1 0.028 13.7 4.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) CDC45 PF02724.14 KIK61709.1 - 2.6 6.2 10.8 0.42 8.9 4.5 2.1 2 0 0 2 2 2 0 CDC45-like protein Peptidase_M20 PF01546.28 KIK61710.1 - 5.1e-11 42.7 0.1 7.1e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK61710.1 - 2.2e-09 37.2 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain FAT PF02259.23 KIK61711.1 - 4.9e-116 387.7 13.4 1.1e-115 386.6 12.1 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KIK61711.1 - 2.2e-66 224.2 0.1 4.7e-66 223.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KIK61711.1 - 2.8e-56 189.9 7.5 3.6e-53 179.8 0.3 5.6 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KIK61711.1 - 1.6e-40 137.5 0.6 1.6e-40 137.5 0.6 4.1 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KIK61711.1 - 2.3e-18 66.4 13.2 6.3e-06 26.5 0.0 9.7 10 0 0 10 10 10 4 HEAT repeats FATC PF02260.20 KIK61711.1 - 1.4e-16 60.0 0.4 4e-16 58.5 0.4 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KIK61711.1 - 1.8e-13 49.5 13.8 0.0025 17.9 0.0 11.8 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 KIK61711.1 - 4.5e-09 36.5 3.1 0.0092 16.0 0.1 4.9 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK61711.1 - 8.8e-09 35.7 10.6 0.19 12.3 0.1 10.8 9 2 2 11 11 10 1 HEAT-like repeat TPR_19 PF14559.6 KIK61711.1 - 7.5e-07 29.6 0.7 0.26 11.8 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 KIK61711.1 - 1.1e-05 25.9 0.1 1.3e+02 3.3 0.0 7.8 8 0 0 8 8 8 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KIK61711.1 - 0.00027 19.6 9.9 0.66 8.5 1.9 5.1 2 1 1 3 3 3 2 Adaptin N terminal region TPR_2 PF07719.17 KIK61711.1 - 0.00036 20.4 0.9 5 7.5 0.1 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK61711.1 - 0.00064 19.6 1.9 0.17 12.0 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3384 PF11864.8 KIK61711.1 - 0.0028 16.6 0.0 0.1 11.5 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) TPR_14 PF13428.6 KIK61711.1 - 0.0097 16.7 1.5 0.64 11.0 0.0 4.8 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK61711.1 - 0.092 12.9 3.8 2.1 8.5 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK61711.1 - 0.58 10.8 2.7 6.8 7.4 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 KIK61711.1 - 1.1 9.5 5.9 62 3.8 0.0 5.7 6 1 1 7 7 6 0 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 KIK61711.1 - 3.2 7.8 6.6 3.1 7.9 0.0 4.4 7 1 0 7 7 5 0 Parkin co-regulated protein Actin PF00022.19 KIK61712.1 - 7.1e-27 94.0 0.0 7e-12 44.7 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 KIK61712.1 - 1.3e-12 47.6 0.0 8.8e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KIK61712.1 - 0.0001 21.3 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 KIK61712.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Cell division protein FtsA FOXP-CC PF16159.5 KIK61713.1 - 0.016 15.8 0.6 0.016 15.8 0.6 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK61713.1 - 0.064 13.7 2.3 0.13 12.8 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type RCC1 PF00415.18 KIK61714.1 - 2.6e-20 72.8 3.2 0.00039 21.0 0.0 6.4 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK61714.1 - 1.3e-10 40.8 18.7 0.00011 21.8 0.3 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KIK61714.1 - 0.026 14.4 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 F-box-like PH_12 PF16457.5 KIK61716.1 - 8.7e-33 113.7 0.0 1.8e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KIK61716.1 - 7.4e-25 87.7 0.0 1.5e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KIK61716.1 - 3.1e-23 82.8 0.0 5.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family TUG-UBL1 PF11470.8 KIK61716.1 - 0.02 15.1 0.3 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 TUG ubiquitin-like domain MTHFR PF02219.17 KIK61717.1 - 2.9e-106 355.0 0.0 4e-106 354.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF202 PF02656.15 KIK61718.1 - 0.0004 20.8 4.4 0.00078 19.8 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF624 PF04854.14 KIK61718.1 - 0.052 13.7 0.2 0.061 13.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF624 CopD PF05425.13 KIK61718.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.1 1 1 0 2 2 2 0 Copper resistance protein D CDC27 PF09507.10 KIK61721.1 - 7.2e-37 127.8 56.4 1.7e-35 123.3 40.4 2.2 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Aa_trans PF01490.18 KIK61722.1 - 2.9e-83 279.9 24.3 3.3e-83 279.7 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIK61722.1 - 3.7e-05 22.9 15.7 3.7e-05 22.9 15.7 2.0 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family ATP-synt_8 PF00895.20 KIK61722.1 - 0.051 14.0 0.5 0.22 12.0 0.5 2.2 1 0 0 1 1 1 0 ATP synthase protein 8 SUZ PF12752.7 KIK61723.1 - 2.3e-13 50.7 0.5 2.3e-13 50.7 0.5 6.7 6 1 0 6 6 6 1 SUZ domain R3H PF01424.22 KIK61723.1 - 0.0036 17.2 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 R3H domain FGGY_N PF00370.21 KIK61724.1 - 3.6e-24 85.7 0.0 2.2e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIK61724.1 - 1.3e-17 64.2 0.0 3.9e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PseudoU_synth_1 PF01416.20 KIK61725.1 - 1.6e-11 44.6 0.0 1.4e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase TcpQ PF10671.9 KIK61725.1 - 0.012 15.8 0.1 0.045 13.9 0.1 1.9 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q RNA_pol_Rpb4 PF03874.16 KIK61726.1 - 2e-18 66.9 0.5 3e-18 66.3 0.5 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb4 RPN6_N PF18055.1 KIK61727.1 - 8.7e-45 151.9 6.4 1.1e-44 151.6 4.1 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KIK61727.1 - 1.9e-16 60.5 1.3 8.3e-16 58.4 0.1 2.4 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KIK61727.1 - 5.4e-11 42.0 0.5 1.7e-10 40.5 0.5 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KIK61727.1 - 0.00017 21.4 6.2 2.6 8.3 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK61727.1 - 0.00087 18.8 4.2 0.019 14.3 4.2 2.4 1 1 1 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 KIK61727.1 - 0.013 15.6 0.9 17 5.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Fanconi_C PF02106.15 KIK61727.1 - 0.056 12.2 2.9 0.085 11.6 2.9 1.3 1 0 0 1 1 1 0 Fanconi anaemia group C protein TPR_1 PF00515.28 KIK61727.1 - 0.26 11.2 1.8 19 5.3 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Mid2 PF04478.12 KIK61728.1 - 0.00011 22.1 1.0 0.00024 21.0 1.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rootletin PF15035.6 KIK61728.1 - 0.089 12.8 4.1 0.15 12.0 4.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Paf67 PF10255.9 KIK61729.1 - 0.0036 16.4 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF1264 PF06884.11 KIK61730.1 - 5.5e-65 218.1 0.0 8.4e-65 217.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Mid2 PF04478.12 KIK61730.1 - 0.0021 17.9 0.6 0.0051 16.6 0.6 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 KIK61730.1 - 0.029 14.6 0.4 0.029 14.6 0.4 2.0 2 0 0 2 2 2 0 Glycophorin A Syndecan PF01034.20 KIK61730.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Tup_N PF08581.10 KIK61730.1 - 1.8 8.9 7.5 15 6.0 1.1 2.5 2 0 0 2 2 2 0 Tup N-terminal DUF1712 PF08217.11 KIK61731.1 - 4.6e-19 68.4 0.0 6.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-CCCH PF00642.24 KIK61732.1 - 5.3e-10 39.0 18.2 0.00011 22.0 1.3 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK61732.1 - 0.00099 19.1 20.5 2.5 8.3 0.8 5.7 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH_3 PF15663.5 KIK61732.1 - 0.012 15.8 2.1 0.012 15.8 2.1 3.3 1 1 2 3 3 3 0 Zinc-finger containing family Torus PF16131.5 KIK61732.1 - 0.078 13.7 0.5 0.078 13.7 0.5 3.9 1 1 3 4 4 4 0 Torus domain CDC45 PF02724.14 KIK61732.1 - 0.39 9.0 2.6 0.47 8.7 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 KIK61732.1 - 1.1 9.1 12.0 0.21 11.5 8.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 KIK61732.1 - 2.3 8.7 13.2 5.5 7.4 13.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Trp_halogenase PF04820.14 KIK61733.1 - 6.7e-27 94.4 2.2 1.6e-13 50.3 0.3 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK61733.1 - 3.1e-16 59.6 0.0 4.4e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK61733.1 - 3e-08 33.5 0.0 4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK61733.1 - 1.3e-06 28.6 1.4 7.3e-06 26.1 0.2 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK61733.1 - 7.2e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK61733.1 - 0.00027 19.8 0.1 0.00038 19.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIK61733.1 - 0.00054 19.2 0.9 0.0013 17.9 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KIK61733.1 - 0.00062 20.3 0.1 0.0025 18.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK61733.1 - 0.0025 17.5 1.2 0.096 12.2 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK61733.1 - 0.004 16.3 0.6 0.0072 15.5 0.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIK61733.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIK61733.1 - 0.082 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF285 PF03382.14 KIK61733.1 - 0.24 11.2 1.5 5.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 UCH PF00443.29 KIK61734.1 - 1.9e-62 211.1 0.0 4.1e-62 210.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KIK61734.1 - 3e-14 53.4 0.6 2.4e-13 50.5 0.0 2.7 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 KIK61734.1 - 1.8e-10 40.9 0.4 1e-05 25.3 0.0 3.5 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 KIK61734.1 - 0.2 11.1 2.0 5.6 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TAFII28 PF04719.14 KIK61735.1 - 4.2e-34 116.5 0.1 5.4e-34 116.1 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KIK61735.1 - 0.0016 18.7 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3742 PF12553.8 KIK61737.1 - 1.4 9.0 4.8 0.57 10.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) F-box-like PF12937.7 KIK61738.1 - 1.2e-08 34.7 1.5 3.5e-08 33.2 1.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK61738.1 - 0.0065 16.9 2.4 2.1 8.9 0.0 4.6 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) Coatomer_E PF04733.14 KIK61739.1 - 4.5e-42 144.5 0.1 5.4e-42 144.2 0.1 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.6 KIK61739.1 - 5.5e-06 26.6 1.1 0.17 12.2 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK61739.1 - 1.4e-05 24.9 2.3 1.2 9.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK61739.1 - 1.8e-05 25.2 7.3 0.12 12.9 0.5 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK61739.1 - 0.0006 20.3 3.4 16 6.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK61739.1 - 0.0031 18.0 0.6 4.9 8.1 1.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK61739.1 - 0.0077 16.4 0.5 0.51 10.7 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK61739.1 - 0.01 15.2 0.0 7.2 5.9 0.0 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_14 PF13428.6 KIK61739.1 - 0.015 16.0 8.8 15 6.7 0.5 5.0 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK61739.1 - 0.019 14.8 1.3 5.1 7.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KIK61739.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 KIK61739.1 - 0.036 14.7 10.7 0.28 11.9 0.1 4.3 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK61739.1 - 0.21 11.7 0.1 0.21 11.7 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat An_peroxidase PF03098.15 KIK61740.1 - 5.5e-34 117.6 0.0 1.9e-22 79.6 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KIK61740.1 - 1e-08 34.4 0.0 1.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_q2 PF00420.24 KIK61740.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF676 PF05057.14 KIK61741.1 - 3.7e-40 137.8 0.0 5.5e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KIK61741.1 - 0.00012 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIK61741.1 - 0.00031 21.4 0.0 0.00052 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KIK61741.1 - 0.0078 16.1 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KIK61741.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KIK61741.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family RMMBL PF07521.12 KIK61741.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain RAP1 PF07218.11 KIK61741.1 - 2.3 6.4 6.3 3.1 6.0 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 KIK61742.1 - 6.4e-74 248.6 0.0 8.5e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61742.1 - 4.7e-49 167.0 0.0 7.4e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KIK61742.1 - 6.2e-23 80.9 0.1 1.4e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KIK61742.1 - 1.7e-05 23.8 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK61742.1 - 0.0036 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK61742.1 - 0.0068 15.8 0.1 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK61742.1 - 0.066 13.1 0.3 0.68 9.8 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 KIK61742.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain ATP_bind_1 PF03029.17 KIK61743.1 - 4.7e-74 249.2 0.0 5.8e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KIK61743.1 - 0.0012 19.0 0.0 0.0031 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIK61743.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 KIK61743.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RRM_1 PF00076.22 KIK61744.1 - 8.7e-25 86.3 0.0 3.7e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KIK61744.1 - 0.11 12.5 0.0 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_5 PF13893.6 KIK61744.1 - 0.12 12.0 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 KIK61745.1 - 3.4e-57 194.1 0.1 8.3e-57 192.9 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KIK61745.1 - 1.8e-21 76.8 0.8 1.8e-21 76.8 0.8 3.8 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KIK61745.1 - 4e-07 29.8 0.0 9.2e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KIK61745.1 - 0.0073 16.7 0.0 7.9 6.9 0.0 4.9 3 0 0 3 3 3 1 HEAT repeats Cohesin_HEAT PF12765.7 KIK61745.1 - 0.074 13.4 0.1 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KIK61745.1 - 4.1 7.9 11.6 0.63 10.4 0.0 5.6 7 0 0 7 7 7 0 HEAT repeat PALP PF00291.25 KIK61746.1 - 9.2e-50 169.7 0.9 1.1e-49 169.5 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PMT PF02366.18 KIK61747.1 - 1.3e-82 277.1 15.6 1.3e-82 277.1 15.6 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIK61747.1 - 1.9e-61 207.1 4.3 1.9e-61 207.1 4.3 3.3 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIK61747.1 - 1.3e-17 64.2 0.8 2.2e-17 63.5 0.8 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIK61747.1 - 1.1e-06 29.0 11.0 1.1e-06 29.0 11.0 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PH_10 PF15411.6 KIK61748.1 - 2.3e-25 89.2 0.0 4.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KIK61748.1 - 5.7e-07 30.0 0.1 4.8e-05 23.7 0.0 2.7 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIK61748.1 - 4.1e-06 26.8 0.0 0.0015 18.5 0.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_UBOX PF13445.6 KIK61748.1 - 0.00018 21.5 1.3 0.00044 20.2 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK61748.1 - 0.00021 21.6 1.5 0.00054 20.2 1.8 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK61748.1 - 0.0013 18.6 0.3 0.0027 17.6 0.3 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK61748.1 - 0.21 11.5 0.1 0.45 10.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK61748.1 - 0.35 10.7 4.6 0.28 11.0 2.5 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK61748.1 - 1.1 9.2 2.5 5.2 7.0 2.7 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 KIK61749.1 - 1.1e-14 54.3 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 PX domain HlyIII PF03006.20 KIK61750.1 - 1.5e-38 132.8 17.0 2.1e-38 132.3 17.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related CREPT PF16566.5 KIK61750.1 - 0.14 12.4 2.4 1 9.5 1.7 2.4 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Pept_tRNA_hydro PF01195.19 KIK61751.1 - 1.1e-23 84.1 0.0 1.4e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase tRNA-synt_2 PF00152.20 KIK61753.1 - 1.4e-89 300.3 0.0 2.4e-89 299.5 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK61753.1 - 2e-07 30.9 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain F-box-like PF12937.7 KIK61754.1 - 3.3e-07 30.1 2.7 1.1e-06 28.4 2.7 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK61754.1 - 1.7 8.6 11.6 3.8 7.5 4.2 3.9 3 1 0 3 3 3 0 F-box domain Dus PF01207.17 KIK61755.1 - 6.1e-52 176.6 0.0 9.9e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 KIK61755.1 - 2.5e-05 24.1 6.5 0.049 13.6 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK61755.1 - 0.0006 19.6 10.0 0.035 13.9 3.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KIK61755.1 - 0.0091 16.7 2.4 0.28 11.9 0.2 2.4 2 0 0 2 2 2 1 Torus domain Herpes_U44 PF04533.13 KIK61755.1 - 0.044 13.4 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpes virus U44 protein G8 PF10162.9 KIK61755.1 - 0.046 13.8 0.2 0.08 13.0 0.2 1.4 1 0 0 1 1 1 0 G8 domain zf_CCCH_4 PF18345.1 KIK61755.1 - 0.34 11.0 10.2 2.7 8.2 0.6 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 KIK61755.1 - 1.8 9.1 5.2 3.8 8.1 0.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Dynactin_p22 PF07426.11 KIK61757.1 - 1e-14 54.8 0.2 1.7e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Dynactin subunit p22 CHIP_TPR_N PF18391.1 KIK61757.1 - 0.019 15.7 1.2 0.061 14.1 0.1 2.3 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DIM1 PF02966.16 KIK61757.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 WcbI PF18588.1 KIK61758.1 - 3.8 7.1 7.3 0.34 10.5 2.2 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI E1-E2_ATPase PF00122.20 KIK61759.1 - 1.4e-48 164.8 4.3 3.5e-48 163.5 4.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIK61759.1 - 8.3e-27 94.8 1.1 9.8e-27 94.6 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIK61759.1 - 1.3e-25 89.6 0.0 8.5e-12 45.3 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIK61759.1 - 0.0035 17.1 0.5 0.0081 15.9 0.3 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4841 PF16129.5 KIK61759.1 - 0.0079 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4841) DeoC PF01791.9 KIK61760.1 - 6.4e-12 45.6 1.2 8.8e-12 45.1 1.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DAHP_snth_FXD PF18152.1 KIK61760.1 - 0.018 14.9 0.0 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain His_biosynth PF00977.21 KIK61760.1 - 0.027 13.9 0.4 0.84 9.0 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein SNF5 PF04855.12 KIK61761.1 - 5.4e-61 206.4 0.0 9.1e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Pox_Ag35 PF03286.14 KIK61761.1 - 0.092 12.5 1.5 0.36 10.6 0.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 KIK61761.1 - 1.3 7.8 6.2 2.2 7.1 6.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CENP-B_dimeris PF09026.10 KIK61761.1 - 5.1 7.5 10.4 17 5.8 5.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1992 PF09350.10 KIK61762.1 - 2.1e-20 72.7 0.1 6e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Methyltransf_23 PF13489.6 KIK61763.1 - 1.7e-23 83.3 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK61763.1 - 1.1e-20 74.1 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK61763.1 - 4.7e-18 65.7 0.0 8.5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK61763.1 - 7.1e-17 62.0 0.0 1.2e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK61763.1 - 1.3e-16 60.8 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK61763.1 - 3e-09 36.6 0.0 4.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KIK61763.1 - 6.6e-07 29.0 0.0 9.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KIK61763.1 - 2.9e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KIK61763.1 - 9.3e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KIK61763.1 - 0.0001 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KIK61763.1 - 0.00038 19.9 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KIK61763.1 - 0.00075 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KIK61763.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIK61763.1 - 0.002 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 KIK61763.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 KIK61763.1 - 0.041 13.0 0.0 0.068 12.2 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Chlamy_scaf PF09675.10 KIK61763.1 - 0.046 14.1 0.1 7 7.1 0.0 2.8 3 1 0 3 3 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) DREV PF05219.12 KIK61763.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase AdoMet_MTase PF07757.13 KIK61763.1 - 0.19 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ShlB PF03865.13 KIK61764.1 - 0.0086 15.6 1.4 1.2 8.5 0.2 2.5 2 0 0 2 2 2 2 Haemolysin secretion/activation protein ShlB/FhaC/HecB Fil_haemagg_2 PF13332.6 KIK61764.1 - 0.029 14.5 14.2 0.27 11.3 1.2 2.7 2 0 0 2 2 2 0 Hemagglutinin repeat Gluconate_2-dh3 PF13618.6 KIK61764.1 - 0.062 13.5 2.8 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 AAA_2 PF07724.14 KIK61765.1 - 2.1e-47 161.4 0.0 4.4e-44 150.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIK61765.1 - 4.3e-34 116.6 6.1 4.8e-34 116.4 0.5 2.7 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KIK61765.1 - 4.5e-22 77.9 4.0 3.4e-21 75.1 0.3 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIK61765.1 - 7.5e-21 74.9 0.1 4.4e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK61765.1 - 3.4e-17 62.7 0.0 1.3e-10 41.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK61765.1 - 4.7e-13 49.9 1.1 7.3e-05 23.2 0.1 4.5 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KIK61765.1 - 4.3e-09 36.8 3.2 0.0016 18.7 0.0 4.7 5 2 0 5 5 4 2 AAA domain Sigma54_activat PF00158.26 KIK61765.1 - 8e-08 32.2 0.0 5.6e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIK61765.1 - 2.6e-06 27.0 0.2 0.11 11.9 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK61765.1 - 2.7e-06 27.9 0.1 0.17 12.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KIK61765.1 - 3.4e-06 27.7 4.4 0.42 11.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KIK61765.1 - 4.4e-06 26.8 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIK61765.1 - 8.1e-06 25.5 0.0 0.044 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIK61765.1 - 1.4e-05 25.1 0.2 0.073 13.0 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_24 PF13479.6 KIK61765.1 - 2.1e-05 24.4 0.0 0.039 13.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIK61765.1 - 2.3e-05 24.2 0.0 0.19 11.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 KIK61765.1 - 5.6e-05 22.9 1.8 0.53 10.0 0.2 3.8 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KIK61765.1 - 6.4e-05 23.3 0.1 0.38 11.0 0.0 3.7 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KIK61765.1 - 6.5e-05 23.5 3.3 0.016 15.7 0.0 3.4 3 1 0 3 3 3 1 ABC transporter Roc PF08477.13 KIK61765.1 - 0.00028 21.1 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KIK61765.1 - 0.0007 20.0 0.0 2.3 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_21 PF13304.6 KIK61765.1 - 0.0013 18.6 5.0 4.8 6.9 0.5 3.6 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KIK61765.1 - 0.0015 18.5 10.8 0.11 12.4 0.2 4.8 3 2 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KIK61765.1 - 0.0081 15.9 0.0 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK61765.1 - 0.011 15.7 0.0 0.86 9.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.18 KIK61765.1 - 0.011 15.6 0.0 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein NTPase_1 PF03266.15 KIK61765.1 - 0.013 15.4 0.3 7.7 6.4 0.0 3.7 4 0 0 4 4 4 0 NTPase AAA_19 PF13245.6 KIK61765.1 - 0.013 15.8 0.2 0.37 11.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK61765.1 - 0.014 15.2 0.1 0.98 9.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KIK61765.1 - 0.014 15.4 0.0 8.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIK61765.1 - 0.02 15.0 0.0 4.9 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KIK61765.1 - 0.026 14.1 0.1 0.87 9.1 0.0 3.0 3 1 0 3 3 2 0 AAA domain SRP54 PF00448.22 KIK61765.1 - 0.03 14.0 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.6 KIK61765.1 - 0.047 13.5 0.3 0.49 10.2 0.0 2.7 2 1 0 2 2 1 0 DNA polymerase III, delta subunit T2SSE PF00437.20 KIK61765.1 - 0.049 12.7 0.0 0.83 8.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein EcoEI_R_C PF08463.10 KIK61765.1 - 0.053 13.6 2.4 0.13 12.3 2.4 1.7 1 0 0 1 1 1 0 EcoEI R protein C-terminal AAA_3 PF07726.11 KIK61765.1 - 0.056 13.3 0.0 14 5.5 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KIK61765.1 - 0.074 12.8 0.0 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 KIK61765.1 - 0.076 13.4 0.0 25 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK61765.1 - 0.078 12.2 0.1 5.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin ATP_bind_1 PF03029.17 KIK61765.1 - 0.086 12.6 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KIK61765.1 - 0.14 12.3 0.0 29 4.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ResIII PF04851.15 KIK61765.1 - 0.14 12.2 0.3 40 4.2 0.0 3.3 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 KIK61765.1 - 0.26 11.0 2.6 13 5.4 1.8 3.0 2 1 0 2 2 2 0 AAA ATPase domain FapA PF03961.13 KIK61765.1 - 0.56 8.8 5.4 0.64 8.5 3.9 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Prefoldin PF02996.17 KIK61765.1 - 2 8.3 8.3 11 5.9 0.4 4.4 4 1 0 4 4 4 0 Prefoldin subunit DUF4349 PF14257.6 KIK61765.1 - 3.5 7.0 14.5 0.094 12.1 4.5 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4349) ADH_N PF08240.12 KIK61766.1 - 8.5e-26 90.0 1.3 1.6e-25 89.1 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK61766.1 - 3.8e-16 59.3 0.0 5.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK61766.1 - 9e-06 25.3 0.1 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ICMT PF04140.14 KIK61767.1 - 1.6e-13 50.9 0.1 1e-12 48.3 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK61767.1 - 4.5e-13 49.5 1.0 2.5e-12 47.1 0.4 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK61767.1 - 0.00021 20.2 0.4 0.00035 19.5 0.4 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KIK61768.1 - 1.5e-13 51.0 2.0 8e-13 48.6 0.0 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK61768.1 - 1.8e-12 47.6 0.7 1.6e-11 44.5 0.3 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK61768.1 - 0.00064 18.6 0.4 0.00092 18.1 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF202 PF02656.15 KIK61768.1 - 0.096 13.1 1.8 0.28 11.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DinB_2 PF12867.7 KIK61769.1 - 0.076 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily Pkinase PF00069.25 KIK61770.1 - 1.8e-59 201.2 0.0 2.5e-58 197.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61770.1 - 4.3e-23 81.9 0.4 2.3e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK61770.1 - 1.8e-05 23.9 0.1 2.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK61770.1 - 0.0047 16.3 0.3 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK61770.1 - 0.021 14.1 3.6 0.019 14.3 0.5 2.4 2 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KIK61770.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIK61770.1 - 0.041 12.7 0.5 0.066 12.0 0.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIK61770.1 - 0.054 13.4 3.5 0.58 10.0 0.5 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KIK61770.1 - 0.48 11.2 2.1 1.2 9.9 2.1 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain WD40 PF00400.32 KIK61772.1 - 1.2e-44 149.4 15.8 8.1e-08 32.8 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat PRP4 PF08799.11 KIK61772.1 - 2.1e-14 52.7 1.3 3.8e-14 51.9 1.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KIK61772.1 - 3.1e-14 53.0 0.0 0.18 12.1 0.0 6.2 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK61772.1 - 1.4e-05 24.5 0.0 0.078 12.3 0.0 3.8 5 0 0 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KIK61772.1 - 0.0062 15.5 0.0 56 2.5 0.0 4.2 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK61772.1 - 0.009 15.4 0.1 3.6 6.8 0.0 3.2 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PKD_channel PF08016.12 KIK61773.1 - 0.0023 16.7 16.5 0.022 13.4 0.3 2.2 2 0 0 2 2 2 2 Polycystin cation channel Haem_degrading PF03928.14 KIK61774.1 - 3.6e-39 133.5 0.1 4.2e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 Haem-degrading RNA_pol_L PF01193.24 KIK61774.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DAO PF01266.24 KIK61775.1 - 1e-39 137.2 0.0 1.1e-39 137.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK61775.1 - 2.5e-05 24.4 0.0 6.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK61775.1 - 0.00023 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIK61775.1 - 0.0071 15.6 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK61775.1 - 0.0074 16.3 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KIK61775.1 - 0.029 13.7 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIK61775.1 - 0.045 13.0 0.0 0.52 9.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIK61775.1 - 0.25 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 MCRA family K_oxygenase PF13434.6 KIK61775.1 - 0.27 10.3 0.0 0.48 9.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TFIIS_M PF07500.14 KIK61776.1 - 2.6e-18 66.5 1.1 2.6e-18 66.5 1.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KIK61776.1 - 4.3e-12 46.2 0.0 7.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 SPOC domain Pkinase PF00069.25 KIK61777.1 - 2.5e-70 236.9 0.0 5.6e-70 235.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61777.1 - 4.8e-51 173.5 0.0 7.3e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 KIK61777.1 - 3.6e-09 36.8 0.0 7.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 KIK61777.1 - 4.9e-07 29.5 5.3 8.4e-07 28.8 5.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KIK61777.1 - 0.011 15.3 7.6 0.021 14.4 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CDC24 PF06395.11 KIK61777.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin Seadorna_VP7 PF07387.11 KIK61777.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIK61777.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KIK61777.1 - 0.16 11.3 0.0 0.78 9.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like PHD PF00628.29 KIK61777.1 - 8.7 6.3 8.0 17 5.4 8.0 1.4 1 0 0 1 1 1 0 PHD-finger LRR_8 PF13855.6 KIK61780.1 - 1.2e-50 169.1 53.3 5.5e-11 42.1 2.0 10.5 6 3 4 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KIK61780.1 - 2e-50 167.9 60.1 4e-06 27.1 0.0 12.2 9 2 3 12 12 12 11 Leucine Rich repeats (2 copies) PP2C PF00481.21 KIK61780.1 - 4.5e-42 144.5 0.0 1.9e-41 142.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 KIK61780.1 - 3.1e-23 82.3 0.0 5.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KIK61780.1 - 1e-07 31.6 16.4 0.081 12.4 1.0 6.1 3 3 4 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 KIK61780.1 - 2.8e-07 30.1 57.7 3.2 8.7 0.3 16.9 17 1 0 17 17 17 3 Leucine Rich Repeat LRR_6 PF13516.6 KIK61780.1 - 4.1e-07 29.5 54.2 0.27 11.4 0.2 13.5 13 0 0 13 13 13 7 Leucine Rich repeat CTP_synth_N PF06418.14 KIK61781.1 - 1.7e-122 407.8 0.7 2.2e-122 407.5 0.7 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KIK61781.1 - 1.2e-51 175.2 0.0 2.1e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK61781.1 - 0.0022 17.8 0.2 0.017 14.9 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KIK61781.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK61781.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase RRM_1 PF00076.22 KIK61782.1 - 6e-16 58.0 0.0 8.5e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3915 PF13054.6 KIK61782.1 - 6.1 6.9 8.8 16 5.5 8.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) F-box-like PF12937.7 KIK61784.1 - 6.8e-07 29.1 0.3 1.3e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK61784.1 - 3.7e-06 26.7 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK61784.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box Glyco_hydro_18 PF00704.28 KIK61785.1 - 1.6e-13 51.1 0.5 3.2e-13 50.1 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pyr_redox_2 PF07992.14 KIK61786.1 - 1.2e-31 110.1 0.0 1.6e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK61786.1 - 3.8e-14 53.0 0.0 2e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK61786.1 - 0.00017 20.8 0.0 0.026 13.7 0.0 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK61786.1 - 0.00037 20.5 0.3 1 9.4 0.1 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK61786.1 - 0.00074 18.9 0.0 0.00074 18.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK61786.1 - 0.0016 18.7 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK61786.1 - 0.0052 16.4 1.1 11 5.5 0.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KIK61786.1 - 0.02 15.2 0.1 3.5 7.9 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain Lycopene_cycl PF05834.12 KIK61786.1 - 0.023 13.7 0.4 1.5 7.8 0.1 2.7 2 1 1 3 3 3 0 Lycopene cyclase protein Syntaxin PF00804.25 KIK61787.1 - 3.9e-33 114.8 8.6 5.6e-33 114.3 8.6 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KIK61787.1 - 5.9e-09 35.8 0.7 1.2e-08 34.8 0.7 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KIK61787.1 - 3.6e-06 27.3 14.2 3.7e-06 27.3 7.4 2.6 2 1 1 3 3 3 1 Syntaxin-like protein Spectrin PF00435.21 KIK61787.1 - 0.0017 18.8 6.2 0.096 13.2 0.0 3.0 3 1 0 3 3 3 2 Spectrin repeat LMBR1 PF04791.16 KIK61787.1 - 0.04 12.8 11.2 0.16 10.9 11.2 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein VitD-bind_III PF09164.10 KIK61787.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III MCPsignal PF00015.21 KIK61787.1 - 0.14 12.0 6.6 0.034 14.0 1.6 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.11 KIK61787.1 - 0.19 12.3 9.6 0.1 13.2 1.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 KIK61787.1 - 0.31 11.4 6.0 1.4 9.2 1.8 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4094 PF13334.6 KIK61787.1 - 0.34 11.4 3.7 7.8 7.0 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF4988 PF16378.5 KIK61787.1 - 0.46 10.1 5.1 0.66 9.6 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function Laminin_II PF06009.12 KIK61787.1 - 0.48 10.4 9.1 2.1 8.3 0.2 2.7 3 0 0 3 3 3 0 Laminin Domain II SKA1 PF07160.12 KIK61787.1 - 0.97 9.2 10.8 0.1 12.4 1.8 2.5 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MCU PF04678.13 KIK61787.1 - 1 9.5 5.4 0.27 11.3 1.1 2.0 1 1 1 2 2 2 0 Mitochondrial calcium uniporter OapA_N PF08525.11 KIK61787.1 - 1.2 9.1 5.4 2.2 8.3 5.4 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif V-SNARE PF05008.15 KIK61787.1 - 1.7 9.1 14.3 0.51 10.7 0.6 4.0 3 3 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Wbp11 PF09429.10 KIK61787.1 - 2.6 8.5 8.1 2 8.9 0.6 2.9 2 1 1 3 3 3 0 WW domain binding protein 11 TMPIT PF07851.13 KIK61787.1 - 2.6 7.2 8.3 6.3 5.9 1.5 2.2 2 0 0 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.19 KIK61787.1 - 4.3 5.1 12.7 1.7 6.5 9.0 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 KIK61787.1 - 4.6 6.9 9.5 0.98 9.1 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) End3 PF12761.7 KIK61787.1 - 5.8 7.0 12.5 1.3 9.1 3.5 2.7 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 CdvA PF18822.1 KIK61787.1 - 6.2 6.7 9.9 1.2 9.0 0.1 3.3 3 2 0 3 3 3 0 CdvA-like coiled-coil domain DUF16 PF01519.16 KIK61787.1 - 6.2 7.4 9.1 0.24 11.9 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Herpes_US9 PF06072.11 KIK61787.1 - 8.1 6.4 7.7 0.2 11.6 0.9 1.8 2 0 0 2 2 1 0 Alphaherpesvirus tegument protein US9 YnfE PF17452.2 KIK61787.1 - 8.3 6.8 7.7 3.9 7.8 0.1 3.2 2 2 1 3 3 3 0 Uncharacterized YnfE-like Tektin PF03148.14 KIK61788.1 - 0.0017 17.2 4.4 0.0023 16.8 4.4 1.1 1 0 0 1 1 1 1 Tektin family Tropomyosin_1 PF12718.7 KIK61788.1 - 0.0053 16.9 2.4 0.0081 16.3 2.4 1.2 1 0 0 1 1 1 1 Tropomyosin like Med30 PF11315.8 KIK61788.1 - 0.008 16.4 1.1 0.14 12.3 0.0 2.1 1 1 1 2 2 2 1 Mediator complex subunit 30 DUF1664 PF07889.12 KIK61788.1 - 0.013 15.6 3.4 0.03 14.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHC_N2 PF08393.13 KIK61788.1 - 0.015 14.4 1.7 0.024 13.8 1.7 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 FlaC_arch PF05377.11 KIK61788.1 - 0.017 15.5 2.9 0.47 10.9 0.2 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 KIK61788.1 - 0.019 13.9 0.5 0.024 13.5 0.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Apolipoprotein PF01442.18 KIK61788.1 - 0.02 14.8 3.5 0.059 13.2 3.6 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IFT57 PF10498.9 KIK61788.1 - 0.025 13.6 2.3 0.032 13.2 2.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myosin_tail_1 PF01576.19 KIK61788.1 - 0.031 12.1 3.3 0.038 11.8 3.3 1.1 1 0 0 1 1 1 0 Myosin tail Sec34 PF04136.15 KIK61788.1 - 0.033 14.1 5.2 0.11 12.3 1.2 2.1 1 1 1 2 2 2 0 Sec34-like family TACC_C PF05010.14 KIK61788.1 - 0.038 13.8 1.8 0.052 13.3 1.8 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Vps54_N PF10475.9 KIK61788.1 - 0.056 12.7 1.9 0.14 11.4 1.8 1.6 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Fib_alpha PF08702.10 KIK61788.1 - 0.07 13.3 5.0 0.11 12.7 5.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KIK61788.1 - 0.093 13.2 4.4 0.7 10.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 KIK61788.1 - 0.11 12.1 3.8 0.2 11.2 0.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region Tup_N PF08581.10 KIK61788.1 - 0.11 12.8 3.4 5.1 7.5 0.1 2.3 1 1 1 2 2 2 0 Tup N-terminal Cortex-I_coil PF09304.10 KIK61788.1 - 0.12 12.6 2.9 2 8.7 0.3 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil YabA PF06156.13 KIK61788.1 - 0.12 13.0 1.3 16 6.2 0.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 KIK61788.1 - 0.13 10.9 1.5 0.16 10.6 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 KIK61788.1 - 0.15 12.1 6.9 0.65 10.0 6.7 1.8 1 1 1 2 2 2 0 Laminin Domain II Sec3_C_2 PF15278.6 KIK61788.1 - 0.16 12.3 2.9 9.9 6.6 0.3 2.3 1 1 1 2 2 2 0 Sec3 exocyst complex subunit Baculo_PEP_C PF04513.12 KIK61788.1 - 0.19 11.8 4.2 0.73 9.9 4.2 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad2 PF08654.10 KIK61788.1 - 0.21 12.0 2.4 0.89 10.0 2.0 1.9 1 1 1 2 2 2 0 DASH complex subunit Dad2 Cauli_AT PF03233.13 KIK61788.1 - 0.23 11.4 2.3 0.34 10.8 0.8 1.8 1 1 1 2 2 2 0 Aphid transmission protein RPW8 PF05659.11 KIK61788.1 - 0.26 11.0 2.3 5.8 6.6 0.5 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2203 PF09969.9 KIK61788.1 - 0.33 11.7 1.6 1.2 9.9 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 KIK61788.1 - 0.35 10.1 4.7 0.37 10.0 3.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein TBCA PF02970.16 KIK61788.1 - 0.48 10.8 3.3 9.9 6.6 1.2 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor A Seryl_tRNA_N PF02403.22 KIK61788.1 - 0.53 10.5 5.6 9.3 6.5 0.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 KIK61788.1 - 0.56 10.5 4.1 4.9 7.5 1.4 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-Q PF13094.6 KIK61788.1 - 0.7 10.1 6.5 1.7 8.8 6.5 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec2p PF06428.11 KIK61788.1 - 0.78 9.7 6.2 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Sec20 PF03908.13 KIK61788.1 - 1.2 9.1 14.4 6.8 6.7 0.9 3.2 2 1 1 3 3 3 0 Sec20 SlyX PF04102.12 KIK61788.1 - 1.4 9.5 5.5 7.1 7.3 0.8 2.5 1 1 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.8 KIK61788.1 - 1.5 8.9 5.8 1.2 9.2 1.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 KIK61788.1 - 1.5 6.6 4.4 1.9 6.4 4.4 1.3 1 1 0 1 1 1 0 Prominin HR1 PF02185.16 KIK61788.1 - 1.6 8.9 7.5 94 3.2 7.5 2.3 1 1 0 1 1 1 0 Hr1 repeat Vps5 PF09325.10 KIK61789.1 - 6.5e-50 169.9 8.5 1.5e-48 165.5 8.5 2.4 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIK61789.1 - 2.9e-23 82.0 0.0 1.7e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR PF03114.18 KIK61789.1 - 0.058 13.0 4.5 0.78 9.3 4.5 2.2 1 1 0 1 1 1 0 BAR domain Arfaptin PF06456.13 KIK61789.1 - 0.076 12.6 1.4 0.13 11.8 0.5 1.7 2 0 0 2 2 2 0 Arfaptin-like domain BAR_3_WASP_bdg PF10456.9 KIK61789.1 - 0.1 12.0 0.6 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein F-box-like PF12937.7 KIK61790.1 - 2.2e-07 30.6 4.3 1.6e-06 27.9 2.7 2.5 1 1 1 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK61790.1 - 0.0084 16.5 0.3 0.046 14.2 0.1 4.2 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 KIK61792.1 - 1.9e-05 24.9 3.8 0.2 12.1 0.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK61792.1 - 0.015 15.0 3.7 0.057 13.2 0.1 3.1 2 1 1 3 3 3 0 Leucine rich repeat PMG PF05287.12 KIK61792.1 - 0.029 14.4 0.1 0.045 13.8 0.0 1.3 1 1 0 1 1 1 0 PMG protein LRR_6 PF13516.6 KIK61792.1 - 0.042 13.9 0.1 10 6.5 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeat DWNN PF08783.11 KIK61793.1 - 5.2e-28 97.1 0.2 1.3e-27 95.8 0.2 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KIK61793.1 - 2.2e-09 37.0 4.6 2.2e-09 37.0 4.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KIK61793.1 - 6.1e-07 29.2 1.7 6.1e-07 29.2 1.7 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KIK61793.1 - 0.0091 15.8 8.9 0.0091 15.8 8.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 KIK61793.1 - 0.012 15.6 0.9 0.036 14.0 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle DNA_pol3_a_NII PF11490.8 KIK61793.1 - 0.036 13.9 1.3 0.11 12.4 1.3 1.8 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II zf-CCHC_5 PF14787.6 KIK61793.1 - 0.039 13.7 0.7 0.039 13.7 0.7 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger MBR1 PF17058.5 KIK61793.1 - 0.32 11.2 4.5 0.24 11.7 2.0 1.9 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 CDK2AP PF09806.9 KIK61793.1 - 0.72 9.9 10.5 1.1 9.3 7.4 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein zf-RING_2 PF13639.6 KIK61793.1 - 8.5 6.8 16.6 0.21 11.9 10.2 1.6 2 0 0 2 2 2 0 Ring finger domain UDPGT PF00201.18 KIK61794.1 - 8.8e-20 71.0 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK61794.1 - 0.0024 17.9 0.0 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KIK61796.1 - 3.3e-18 65.8 0.0 5.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK61796.1 - 0.0025 17.8 0.0 0.0072 16.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ERG4_ERG24 PF01222.17 KIK61797.1 - 1.2e-130 436.1 24.9 1.4e-130 435.9 24.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK61797.1 - 2.6e-06 27.2 3.1 5.4e-06 26.1 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK61797.1 - 0.00011 22.6 0.7 0.0039 17.6 0.1 2.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Asp PF00026.23 KIK61798.1 - 1.8e-37 129.4 0.6 7.3e-24 84.8 1.6 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK61798.1 - 4.1e-06 27.1 2.5 0.00016 22.0 2.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ubiquitin PF00240.23 KIK61800.1 - 4.7e-18 64.7 0.3 7.7e-18 64.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK61800.1 - 4.6e-09 36.0 0.3 7.6e-09 35.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KIK61800.1 - 1.3e-08 34.6 0.1 1.3e-08 34.6 0.1 2.9 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.9 KIK61800.1 - 6.4e-06 26.7 0.1 1.1e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 KIK61800.1 - 7.5e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK61800.1 - 0.034 14.3 0.1 0.077 13.1 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RPN13_C PF16550.5 KIK61800.1 - 0.068 13.4 4.4 0.75 10.0 0.4 2.6 1 1 1 2 2 2 0 UCH-binding domain Ubiquitin_4 PF18036.1 KIK61800.1 - 0.085 12.9 0.6 0.43 10.7 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KIK61800.1 - 0.2 12.1 0.3 0.53 10.8 0.3 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain XPC-binding PF09280.11 KIK61800.1 - 2.3 8.0 19.1 20 5.0 10.1 3.8 3 1 0 3 3 3 0 XPC-binding domain STI1 PF17830.1 KIK61800.1 - 9 6.3 19.8 1.1 9.3 7.1 3.6 3 1 0 3 3 3 0 STI1 domain TraH_2 PF06871.11 KIK61801.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 TraH_2 Pkinase PF00069.25 KIK61802.1 - 4.2e-19 68.9 0.0 4.5e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61802.1 - 4.3e-09 36.0 0.0 4.5e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KIK61802.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KIK61802.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KIK61802.1 - 0.22 10.8 0.0 0.22 10.8 0.0 1.0 1 0 0 1 1 1 0 Kinase-like BtpA PF03437.15 KIK61804.1 - 0.059 12.8 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 BtpA family DUF2162 PF09930.9 KIK61804.1 - 0.086 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) F-box-like PF12937.7 KIK61805.1 - 1.2e-07 31.4 0.7 4.5e-07 29.7 0.7 2.1 1 0 0 1 1 1 1 F-box-like DUF2095 PF09868.9 KIK61805.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) LRR_8 PF13855.6 KIK61805.1 - 0.99 9.2 3.7 9.4 6.1 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat MMgT PF10270.9 KIK61806.1 - 1.8e-14 53.9 0.0 2.2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Zw10 PF06248.13 KIK61807.1 - 8.2e-15 54.4 0.1 9.8e-09 34.3 0.4 3.0 3 1 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KIK61807.1 - 2.8e-09 37.0 0.1 7.5e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal CHASE3 PF05227.13 KIK61807.1 - 0.27 11.2 2.5 4.1 7.3 0.0 3.0 3 1 0 3 3 3 0 CHASE3 domain polyprenyl_synt PF00348.17 KIK61808.1 - 3.1e-62 209.9 0.0 3.2e-58 196.8 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase PCP PF02429.15 KIK61808.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein Glycophorin_A PF01102.18 KIK61809.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A HhH-GPD PF00730.25 KIK61810.1 - 4.6e-12 46.3 0.0 7.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIK61810.1 - 0.03 14.2 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif RED_N PF07808.13 KIK61811.1 - 1e-15 58.0 9.1 1e-15 58.0 9.1 2.5 3 0 0 3 3 3 1 RED-like protein N-terminal region DNA_methylase PF00145.17 KIK61812.1 - 4e-55 187.5 0.0 1.5e-54 185.6 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIK61812.1 - 1.5e-20 73.3 0.1 4e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 BAH domain Cons_hypoth95 PF03602.15 KIK61812.1 - 0.035 13.8 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-C3HC4 PF00097.25 KIK61812.1 - 3.7 7.5 5.3 0.66 9.9 1.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MBOAT PF03062.19 KIK61813.1 - 1.2e-35 123.5 27.8 1.6e-34 119.8 19.5 3.2 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KIK61813.1 - 0.0041 17.3 3.0 0.0041 17.3 3.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F-box PF00646.33 KIK61815.1 - 4.9e-07 29.5 0.4 1.1e-06 28.3 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK61815.1 - 1.8e-06 27.7 0.0 4.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 KIK61815.1 - 9.1e-05 22.3 0.2 0.00018 21.4 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 KIK61815.1 - 0.00096 19.2 0.2 0.0018 18.3 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KIK61815.1 - 0.0022 17.9 0.2 0.007 16.3 0.2 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK61815.1 - 0.0026 17.5 0.1 0.0044 16.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK61815.1 - 0.0056 17.4 0.3 0.017 15.9 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK61815.1 - 0.013 16.1 0.1 0.13 12.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box_4 PF15966.5 KIK61815.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 F-box TPR_16 PF13432.6 KIK61815.1 - 0.082 13.6 0.2 0.16 12.6 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SelP_N PF04592.14 KIK61815.1 - 0.19 11.1 3.7 0.41 10.0 3.7 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4451 PF14616.6 KIK61817.1 - 5.2e-08 33.1 2.4 0.088 13.0 0.1 3.9 3 1 1 4 4 4 4 Domain of unknown function (DUF4451) zf-Di19 PF05605.12 KIK61817.1 - 0.0058 16.9 1.3 25 5.2 0.0 3.7 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIK61817.1 - 2.2 8.8 5.4 3.9 8.1 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DZR PF12773.7 KIK61817.1 - 4.7 7.3 5.2 12 6.0 0.1 3.4 4 0 0 4 4 4 0 Double zinc ribbon Aldo_ket_red PF00248.21 KIK61818.1 - 1.1e-46 159.3 0.0 1.3e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ESCRT-II PF05871.12 KIK61818.1 - 0.0087 16.3 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit DnaJ PF00226.31 KIK61819.1 - 3.1e-23 81.7 0.1 6.6e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KIK61819.1 - 3.1e-20 72.4 0.3 3.1e-20 72.4 0.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1977) Tau95_N PF17682.1 KIK61819.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Tau95 Triple barrel domain Macoilin PF09726.9 KIK61819.1 - 1 7.8 6.9 1.6 7.2 6.9 1.2 1 0 0 1 1 1 0 Macoilin family NCE101 PF11654.8 KIK61820.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Non-classical export protein 1 WD40 PF00400.32 KIK61821.1 - 1.9e-09 38.0 5.1 0.35 11.8 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF2070 PF09843.9 KIK61822.1 - 4.8 5.4 8.2 4.8 5.4 8.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) F-box-like PF12937.7 KIK61823.1 - 5e-09 35.9 2.3 8.8e-09 35.1 0.9 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK61823.1 - 0.049 14.1 1.7 17 6.0 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK61823.1 - 0.81 9.6 3.3 5 7.1 3.3 2.2 1 1 0 1 1 1 0 F-box domain p450 PF00067.22 KIK61824.1 - 1.8e-54 185.2 0.0 2.1e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.6 KIK61826.1 - 3.5e-08 33.6 0.0 4.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK61826.1 - 0.00057 19.2 0.0 0.00057 19.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK61826.1 - 0.0012 17.4 0.0 0.0014 17.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 KIK61826.1 - 0.0023 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK61826.1 - 0.007 15.6 0.1 0.0094 15.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK61826.1 - 0.017 14.4 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KIK61826.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK61826.1 - 0.017 15.6 0.0 0.026 15.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIK61826.1 - 0.034 13.5 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIK61826.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK61826.1 - 0.25 10.4 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIK61826.1 - 0.3 9.8 0.0 0.38 9.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Phage_integrase PF00589.22 KIK61827.1 - 7.6e-05 22.6 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KIK61827.1 - 0.21 11.9 0.0 0.46 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FMO-like PF00743.19 KIK61828.1 - 4.9e-28 97.8 0.0 1.2e-17 63.5 0.0 3.8 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK61828.1 - 8.3e-13 48.2 0.0 3.1e-11 43.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK61828.1 - 9.2e-12 44.8 0.0 1e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK61828.1 - 2.3e-07 30.9 0.1 1.3e-06 28.5 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK61828.1 - 3e-05 24.5 1.3 0.062 13.9 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK61828.1 - 0.00037 19.7 0.2 0.0045 16.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KIK61828.1 - 0.019 14.2 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KIK61828.1 - 0.059 12.9 1.5 0.13 11.8 0.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK61828.1 - 0.079 12.9 0.1 1.1 9.2 0.0 2.9 3 2 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KIK61828.1 - 0.21 10.8 0.7 0.44 9.7 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain CwfJ_C_1 PF04677.15 KIK61829.1 - 1.7e-28 98.9 0.0 2.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 KIK61829.1 - 2.2e-24 84.9 15.1 7.8e-10 38.4 0.8 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 KIK61829.1 - 2e-10 41.4 0.0 4.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KIK61829.1 - 2.2e-10 40.1 9.5 0.0044 17.0 0.0 3.7 3 0 0 3 3 3 3 Zinc knuckle Zn_ribbon_SprT PF17283.2 KIK61829.1 - 1.1 9.2 5.0 20 5.2 0.1 3.2 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-CCHC_3 PF13917.6 KIK61829.1 - 2.5 8.2 6.9 44 4.1 2.5 3.3 2 1 1 3 3 3 0 Zinc knuckle DUF237 PF03072.14 KIK61830.1 - 0.00083 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF237) SelP_N PF04592.14 KIK61831.1 - 1.1 8.7 6.5 1.3 8.4 6.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1492 PF07374.11 KIK61832.1 - 0.11 12.7 2.5 0.14 12.3 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Tautomerase_2 PF14552.6 KIK61832.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Tautomerase enzyme PFU PF09070.11 KIK61833.1 - 1e-42 144.9 0.2 1.8e-42 144.1 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KIK61833.1 - 3.1e-32 110.1 16.2 7.7e-07 29.7 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat PUL PF08324.11 KIK61833.1 - 5.3e-32 111.1 0.0 7.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.6 KIK61833.1 - 4.6e-06 26.6 0.0 0.033 14.2 0.0 3.2 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region F-box-like PF12937.7 KIK61834.1 - 6.7e-07 29.1 0.0 2.6e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK61834.1 - 0.34 11.4 13.2 4.7 7.8 0.3 5.4 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) HicB PF05534.12 KIK61835.1 - 0.052 13.4 0.3 23 4.9 0.0 3.3 3 0 0 3 3 3 0 HicB family GIT_CC PF16559.5 KIK61835.1 - 0.092 12.6 0.5 0.22 11.4 0.5 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor F-box-like PF12937.7 KIK61837.1 - 7.4e-06 25.8 0.1 2e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Ferric_reduct PF01794.19 KIK61838.1 - 2.3e-14 53.6 10.5 2.3e-14 53.6 10.5 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK61838.1 - 7.3e-14 51.8 0.0 1.9e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NTPase_1 PF03266.15 KIK61842.1 - 0.0072 16.2 0.0 0.046 13.6 0.0 1.8 1 1 1 2 2 2 1 NTPase RNA_helicase PF00910.22 KIK61842.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KIK61842.1 - 0.02 14.8 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIK61842.1 - 0.068 12.3 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KIK61842.1 - 0.095 13.2 0.8 0.1 13.1 0.8 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KIK61842.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KIK61842.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KIK61842.1 - 0.15 12.5 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIK61842.1 - 0.18 11.9 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK61842.1 - 0.19 12.2 0.1 0.25 11.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK61843.1 - 2.8e-76 249.5 53.7 1.3e-10 41.7 0.3 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK61843.1 - 9e-38 128.5 2.6 0.0049 17.1 0.0 10.5 3 2 8 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK61843.1 - 1.2e-18 66.5 21.0 1.1 9.3 0.0 11.3 11 0 0 11 11 11 6 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK61843.1 - 8.6e-18 64.4 18.7 0.075 12.0 0.0 10.3 3 3 5 10 10 10 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK61843.1 - 1.8e-09 37.7 10.9 0.035 13.9 0.2 6.5 3 2 2 5 5 5 3 Lipoprotein LpqB beta-propeller domain Frtz PF11768.8 KIK61843.1 - 3.5e-08 32.2 0.0 0.0062 14.9 0.0 4.6 4 2 1 5 5 5 3 WD repeat-containing and planar cell polarity effector protein Fritz Ret2_MD PF18528.1 KIK61843.1 - 1e-05 25.8 0.6 41 4.7 0.0 7.4 4 3 5 9 9 9 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nup160 PF11715.8 KIK61843.1 - 1.5e-05 23.8 12.8 0.12 11.0 0.1 6.4 4 3 3 7 7 7 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK61843.1 - 0.00034 20.0 0.3 4.1 6.7 0.0 5.1 4 2 0 4 4 4 1 WD40-like domain PQQ PF01011.21 KIK61843.1 - 0.0021 17.9 2.5 11 6.1 0.0 5.5 7 0 0 7 7 7 1 PQQ enzyme repeat Nbas_N PF15492.6 KIK61843.1 - 0.0054 16.1 6.7 2.6 7.3 0.0 6.1 4 3 4 8 8 8 1 Neuroblastoma-amplified sequence, N terminal rOmpB PF12334.8 KIK61843.1 - 0.15 11.6 11.3 5.2 6.5 0.1 5.7 4 2 1 7 7 7 0 Rickettsia outer membrane protein B WD40_3 PF15911.5 KIK61843.1 - 0.76 9.8 3.7 1e+02 3.0 0.0 5.5 8 0 0 8 8 8 0 WD domain, G-beta repeat Aha1_N PF09229.11 KIK61844.1 - 1.7e-30 106.0 0.1 2.9e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KIK61844.1 - 9.3e-14 51.7 0.0 1.9e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein CE2_N PF17996.1 KIK61846.1 - 0.00027 20.9 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal DUF3149 PF11346.8 KIK61846.1 - 0.055 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Pkinase PF00069.25 KIK61847.1 - 6.9e-10 38.7 0.2 2e-08 33.9 0.2 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK61847.1 - 2e-09 37.1 2.2 7.9e-07 28.6 2.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK61847.1 - 0.011 15.0 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK61847.1 - 0.014 14.2 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Septin PF00735.18 KIK61848.1 - 8.9e-114 379.5 1.2 1.1e-113 379.3 1.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIK61848.1 - 2.5e-08 34.0 0.1 5.2e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK61848.1 - 4.7e-07 29.3 0.0 8.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK61848.1 - 1.5e-06 28.2 0.3 2.9e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIK61848.1 - 1.9e-06 27.5 0.6 0.00028 20.5 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KIK61848.1 - 7.1e-05 22.1 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Dynamin_N PF00350.23 KIK61848.1 - 0.00019 21.6 0.7 0.14 12.2 0.2 2.4 1 1 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 KIK61848.1 - 0.00066 19.1 0.0 0.0041 16.5 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KIK61848.1 - 0.0013 19.2 0.0 0.0032 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIK61848.1 - 0.003 18.1 0.4 0.0043 17.6 0.4 1.6 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KIK61848.1 - 0.0039 16.6 0.2 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region T2SSE PF00437.20 KIK61848.1 - 0.0045 16.1 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.12 KIK61848.1 - 0.0045 16.7 0.0 3.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIK61848.1 - 0.0055 16.2 0.1 0.062 12.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Ras PF00071.22 KIK61848.1 - 0.023 14.3 0.5 0.065 12.8 0.1 2.0 2 0 0 2 2 2 0 Ras family Roc PF08477.13 KIK61848.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK61848.1 - 0.029 14.7 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KIK61848.1 - 0.031 13.3 0.2 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KIK61848.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KIK61848.1 - 0.043 13.8 0.1 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIK61848.1 - 0.068 12.3 0.3 0.44 9.6 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 KIK61848.1 - 0.13 12.7 0.6 0.25 11.8 0.6 1.6 1 1 0 1 1 1 0 AAA domain Amnionless PF14828.6 KIK61851.1 - 0.0019 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Amnionless Mid2 PF04478.12 KIK61851.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cupin_5 PF06172.11 KIK61851.1 - 0.14 12.4 0.0 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily (DUF985) EphA2_TM PF14575.6 KIK61851.1 - 0.18 12.7 0.0 0.45 11.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4482 PF14818.6 KIK61851.1 - 0.21 12.4 3.5 0.48 11.3 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) FlxA PF14282.6 KIK61853.1 - 0.00074 19.5 0.7 0.00076 19.4 0.7 1.2 1 0 0 1 1 1 1 FlxA-like protein DUF2383 PF09537.10 KIK61853.1 - 0.0049 17.2 0.2 0.0056 17.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) MerR-DNA-bind PF09278.11 KIK61853.1 - 0.0082 16.7 1.0 0.012 16.2 1.0 1.3 1 0 0 1 1 1 1 MerR, DNA binding Prefoldin PF02996.17 KIK61853.1 - 0.021 14.7 0.3 0.029 14.3 0.3 1.1 1 0 0 1 1 1 0 Prefoldin subunit HOOK PF05622.12 KIK61853.1 - 0.028 12.6 0.0 0.028 12.6 0.0 1.0 1 0 0 1 1 1 0 HOOK protein L31 PF09784.9 KIK61853.1 - 0.1 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 FlxA PF14282.6 KIK61854.1 - 0.00047 20.1 1.2 1.1 9.3 0.9 2.7 2 0 0 2 2 2 2 FlxA-like protein Adeno_E3_CR2 PF02439.15 KIK61854.1 - 0.014 15.1 0.2 0.027 14.2 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SlyX PF04102.12 KIK61854.1 - 0.026 15.1 2.0 0.59 10.8 0.0 2.4 2 0 0 2 2 2 0 SlyX EphA2_TM PF14575.6 KIK61854.1 - 0.1 13.5 0.0 0.29 12.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4482 PF14818.6 KIK61854.1 - 0.18 12.7 0.9 0.54 11.1 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Prefoldin PF02996.17 KIK61854.1 - 1.7 8.6 3.4 30 4.6 0.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit Pico_P1A PF02226.16 KIK61854.1 - 2.5 8.2 7.1 0.32 11.1 0.2 2.9 2 1 1 3 3 3 0 Picornavirus coat protein (VP4) PKcGMP_CC PF16808.5 KIK61854.1 - 5.1 7.0 7.0 9.2 6.2 7.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KIK61855.1 - 0.0045 17.6 7.1 0.033 14.8 0.1 2.4 2 0 0 2 2 2 1 SlyX DUF4140 PF13600.6 KIK61855.1 - 0.036 14.5 1.5 4.4 7.8 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TrbC PF04956.13 KIK61855.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 TrbC/VIRB2 family CD34_antigen PF06365.12 KIK61855.1 - 0.067 12.8 0.4 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 CD34/Podocalyxin family HOOK PF05622.12 KIK61855.1 - 0.078 11.1 3.3 0.21 9.7 0.7 1.9 1 1 0 2 2 2 0 HOOK protein Adeno_E3_CR2 PF02439.15 KIK61855.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LPP PF04728.13 KIK61855.1 - 0.15 12.5 5.8 1.4 9.3 0.5 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 KIK61855.1 - 0.78 10.0 4.8 7.2 6.9 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 KIK61855.1 - 2.5 8.5 6.0 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain HemX PF04375.14 KIK61855.1 - 2.8 7.1 7.2 4.6 6.4 7.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FAD_binding_3 PF01494.19 KIK61856.1 - 7.9e-12 45.1 0.0 1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK61856.1 - 0.00064 19.9 0.1 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK61856.1 - 0.0056 16.3 0.1 1.1 8.8 0.0 2.7 2 2 1 3 3 3 2 FAD dependent oxidoreductase AAA_12 PF13087.6 KIK61858.1 - 9.6e-59 198.4 0.0 1.1e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK61858.1 - 8.2e-09 35.6 0.1 1.2e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK61858.1 - 3e-05 23.9 0.0 0.019 14.7 0.0 2.1 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Ribosomal_S13_N PF08069.12 KIK61858.1 - 0.0027 17.7 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain DUF2075 PF09848.9 KIK61858.1 - 0.059 12.6 0.3 7.2 5.7 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KIK61858.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase MFS_1 PF07690.16 KIK61860.1 - 1.2e-32 113.2 26.6 1.8e-32 112.6 26.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CBF PF03914.17 KIK61861.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 CBF/Mak21 family DUF996 PF06195.13 KIK61861.1 - 0.14 12.4 8.7 1.9 8.8 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF2244 PF10003.9 KIK61861.1 - 0.42 10.3 0.0 0.42 10.3 0.0 2.3 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) CBF PF03914.17 KIK61862.1 - 0.023 14.8 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 CBF/Mak21 family Ac76 PF05814.11 KIK61862.1 - 0.11 12.6 3.8 0.11 12.5 0.3 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Ac76 PF05814.11 KIK61863.1 - 0.052 13.6 0.5 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 Orf76 (Ac76) AhpC-TSA PF00578.21 KIK61866.1 - 3.2e-36 124.0 0.0 4.2e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK61866.1 - 4.1e-15 55.8 0.0 5.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIK61866.1 - 4.7e-11 42.4 0.0 8.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KIK61866.1 - 0.038 13.9 0.0 0.097 12.6 0.0 1.6 2 0 0 2 2 2 0 SCO1/SenC CBM60 PF16841.5 KIK61867.1 - 0.0072 16.7 0.2 0.019 15.4 0.2 1.7 1 0 0 1 1 1 1 Ca-dependent carbohydrate-binding module xylan-binding HORMA PF02301.18 KIK61869.1 - 2.8e-63 213.3 0.0 4.8e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 HORMA domain MarR PF01047.22 KIK61869.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 MarR family MFS_1 PF07690.16 KIK61870.1 - 7.6e-13 48.1 20.6 9e-10 38.0 18.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK61870.1 - 0.14 11.0 9.5 0.094 11.6 0.5 2.4 1 1 1 2 2 2 0 Sugar (and other) transporter L6_membrane PF05805.12 KIK61871.1 - 0.0016 18.0 1.6 0.0021 17.7 1.6 1.1 1 0 0 1 1 1 1 L6 membrane protein His_Phos_1 PF00300.22 KIK61872.1 - 1.7e-27 96.4 1.2 8.1e-27 94.2 1.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Na_Ca_ex PF01699.24 KIK61873.1 - 7.9e-39 133.0 37.3 2.8e-22 79.3 13.0 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein 6PGD PF00393.19 KIK61874.1 - 7.4e-94 314.4 0.0 9e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIK61874.1 - 5e-26 91.8 0.0 9.4e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase BTB PF00651.31 KIK61875.1 - 0.0041 17.3 0.1 0.0097 16.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-RVT PF13966.6 KIK61876.1 - 9.6e-07 29.4 3.2 2.7e-06 28.0 3.2 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KIK61876.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNase H AbiJ_NTD4 PF18863.1 KIK61876.1 - 0.11 12.9 1.8 0.18 12.2 1.8 1.5 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 BTB PF00651.31 KIK61878.1 - 0.0024 18.1 0.0 0.006 16.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain CdAMP_rec PF06153.11 KIK61879.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyclic-di-AMP receptor Sec63 PF02889.16 KIK61881.1 - 4e-14 52.4 0.0 1.6e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KIK61881.1 - 2.6e-06 27.3 0.0 8.9e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase BTB PF00651.31 KIK61884.1 - 0.00091 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Hva1_TUDOR PF11160.8 KIK61885.1 - 4.9e-09 36.2 2.6 4.9e-09 36.2 2.6 1.4 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain BTB PF00651.31 KIK61886.1 - 0.0081 16.4 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain OFeT_1 PF16955.5 KIK61886.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter His_Phos_2 PF00328.22 KIK61887.1 - 6.2e-49 167.3 0.0 7.6e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hva1_TUDOR PF11160.8 KIK61888.1 - 1.8e-18 66.4 3.5 2.5e-18 66.0 3.5 1.2 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Chitin_synth_2 PF03142.15 KIK61889.1 - 3.5e-17 62.2 0.1 3.7e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Chitin synthase Peptidase_C14 PF00656.22 KIK61890.1 - 2e-22 80.4 0.0 2.8e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain GATA PF00320.27 KIK61891.1 - 2.1e-14 52.8 6.7 4.3e-14 51.8 6.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KIK61891.1 - 1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KIK61891.1 - 0.00017 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KIK61891.1 - 0.004 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 KIK61891.1 - 0.009 16.1 0.3 0.019 15.1 0.3 1.6 1 0 0 1 1 1 1 Zinc ribbon domain zf-piccolo PF05715.13 KIK61891.1 - 0.17 12.0 1.6 19 5.5 2.7 2.3 1 1 1 2 2 2 0 Piccolo Zn-finger Rubredoxin_2 PF18073.1 KIK61891.1 - 0.32 10.8 3.0 1 9.1 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF1180 PF06679.12 KIK61891.1 - 0.4 11.1 1.2 0.61 10.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) adh_short_C2 PF13561.6 KIK61892.1 - 6.2e-58 196.1 0.2 7.8e-58 195.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK61892.1 - 1.1e-44 152.2 1.0 3.3e-44 150.7 1.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK61892.1 - 2.7e-11 43.7 0.1 5e-11 42.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK61892.1 - 0.00019 21.0 0.3 0.00084 18.9 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIK61892.1 - 0.00021 20.5 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KIK61892.1 - 0.09 11.8 0.0 0.16 10.9 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Kinesin PF00225.23 KIK61893.1 - 9.5e-98 327.2 0.0 4.3e-56 190.3 0.0 5.4 4 1 1 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 KIK61893.1 - 2.5e-23 82.6 0.0 1.4e-22 80.2 0.0 2.4 1 0 0 1 1 1 1 Microtubule binding DUF641 PF04859.12 KIK61893.1 - 0.0077 16.6 9.1 0.0077 16.6 9.1 14.3 5 3 8 16 16 16 3 Plant protein of unknown function (DUF641) DUF2247 PF10004.9 KIK61893.1 - 1.7 8.4 6.6 0.53 10.1 0.7 3.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) MotB_plug PF13677.6 KIK61894.1 - 0.37 10.4 3.5 0.64 9.7 3.5 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB TMEM171 PF15471.6 KIK61894.1 - 3.5 6.5 5.1 5.4 5.9 5.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 COesterase PF00135.28 KIK61899.1 - 6.6e-89 299.1 0.0 4.9e-88 296.2 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK61899.1 - 0.00098 19.0 0.1 0.0035 17.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK61899.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KIK61900.1 - 1.2e-86 291.7 0.0 3.4e-85 286.9 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK61900.1 - 1.2e-05 25.3 0.1 0.077 12.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK61900.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family TMCCDC2 PF15844.5 KIK61901.1 - 1 9.3 9.0 1.4 8.8 4.7 2.7 1 1 1 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 TMEM208_SND2 PF05620.11 KIK61901.1 - 1.6 8.5 7.8 0.11 12.3 1.1 2.3 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DHBP_synthase PF00926.19 KIK61903.1 - 2.4e-81 271.8 0.0 2.9e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Spherulin4 PF12138.8 KIK61904.1 - 4.8e-56 190.1 0.1 5.6e-56 189.9 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Spherulin4 PF12138.8 KIK61905.1 - 1.9e-61 207.8 0.0 2.2e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Oxidored_q2 PF00420.24 KIK61906.1 - 0.057 13.0 0.6 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MtN3_slv PF03083.16 KIK61906.1 - 0.22 11.6 0.3 0.22 11.6 0.3 1.7 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange KASH PF10541.9 KIK61907.1 - 0.015 15.5 1.3 7.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain NACHT PF05729.12 KIK61908.1 - 3.7e-09 36.7 0.0 7.2e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61908.1 - 6e-07 30.0 0.0 9.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61908.1 - 1.3e-06 28.8 0.0 2.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK61908.1 - 3.9e-05 23.7 0.0 5.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK61908.1 - 0.00025 20.4 0.1 0.52 9.5 0.0 2.1 1 1 0 2 2 2 2 KAP family P-loop domain AAA_7 PF12775.7 KIK61908.1 - 0.0066 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK61908.1 - 0.0095 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 KIK61908.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK61908.1 - 0.044 14.3 0.0 0.076 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK61908.1 - 0.068 12.3 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KIK61908.1 - 0.074 12.8 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK61908.1 - 0.094 12.7 0.2 1.2 9.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF659 PF04937.15 KIK61911.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EPL1 PF10513.9 KIK61912.1 - 1.2e-19 71.3 0.1 1.2e-19 71.3 0.1 3.6 4 2 1 5 5 5 1 Enhancer of polycomb-like Dus PF01207.17 KIK61914.1 - 3.8e-68 229.9 0.0 4.9e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 KIK61914.1 - 0.00043 20.1 0.1 0.013 15.3 0.0 2.2 1 1 1 2 2 2 2 SOR/SNZ family ThiG PF05690.14 KIK61914.1 - 0.00045 19.6 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Mannitol_dh_C PF08125.13 KIK61916.1 - 4e-45 154.2 0.0 6e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KIK61916.1 - 8.8e-22 77.9 1.4 1.5e-21 77.1 0.0 2.1 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain HGTP_anticodon PF03129.20 KIK61916.1 - 0.056 13.6 0.0 2.8 8.2 0.0 3.1 3 0 0 3 3 3 0 Anticodon binding domain Baculo_E56 PF04639.12 KIK61916.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope UDPG_MGDP_dh_N PF03721.14 KIK61916.1 - 0.1 12.2 0.2 0.26 10.8 0.2 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_oprn_chp PF09534.10 KIK61918.1 - 0.096 12.5 1.3 0.15 11.9 1.3 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ADK PF00406.22 KIK61919.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Adenylate kinase WD40 PF00400.32 KIK61921.1 - 1.3e-66 218.9 34.4 2.5e-10 40.8 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK61921.1 - 9.7e-26 89.9 1.9 0.0016 18.7 0.1 6.8 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK61921.1 - 8.7e-19 67.6 3.1 0.0036 16.3 0.1 7.3 2 1 4 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK61921.1 - 6.5e-12 45.7 0.0 0.0053 16.7 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK61921.1 - 1.8e-08 34.1 15.7 5.2 7.1 0.0 8.1 8 0 0 8 8 8 4 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK61921.1 - 7.5e-08 32.0 0.0 0.01 15.2 0.0 3.9 1 1 3 4 4 4 3 WD40-like domain Cytochrom_D1 PF02239.16 KIK61921.1 - 1.1e-07 30.7 0.7 0.04 12.5 0.0 3.5 2 2 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 KIK61921.1 - 1.6e-07 30.4 10.7 0.067 11.8 0.0 5.0 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Frtz PF11768.8 KIK61921.1 - 6.5e-07 28.0 0.0 0.00069 18.1 0.0 3.6 2 2 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK61921.1 - 0.00026 20.6 8.0 0.023 14.3 2.5 2.7 1 1 1 2 2 2 2 PQQ-like domain DUF1513 PF07433.11 KIK61921.1 - 0.0022 17.2 1.0 8.2 5.4 0.0 3.6 1 1 4 5 5 5 1 Protein of unknown function (DUF1513) Nbas_N PF15492.6 KIK61921.1 - 0.0056 16.0 2.5 12 5.1 0.0 4.2 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KIK61921.1 - 0.035 13.0 1.0 9.2 5.1 0.0 3.3 1 1 3 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 KIK61921.1 - 0.44 10.3 8.0 63 3.4 0.0 5.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KIK61921.1 - 0.51 10.9 10.0 22 5.7 0.6 5.3 6 0 0 6 6 6 0 PQQ-like domain Trp_oprn_chp PF09534.10 KIK61922.1 - 2.1 8.1 12.8 0.68 9.7 8.5 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pro-kuma_activ PF09286.11 KIK61923.1 - 6.9e-28 97.7 0.2 1.2e-27 96.9 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Pro-kuma_activ PF09286.11 KIK61924.1 - 6.5e-34 117.3 4.5 3.6e-33 114.8 1.9 2.7 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK61924.1 - 0.001 18.4 1.1 0.0018 17.6 0.4 1.7 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.11 KIK61925.1 - 4.5e-32 111.3 0.4 4.1e-31 108.2 0.8 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain EPL1 PF10513.9 KIK61927.1 - 8.8e-20 71.7 0.3 8.8e-20 71.7 0.3 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like Peptidase_A4 PF01828.17 KIK61928.1 - 1.7e-60 204.1 13.9 2.1e-60 203.8 13.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.17 KIK61929.1 - 1.1e-58 198.2 17.6 1.3e-58 197.9 17.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family WW PF00397.26 KIK61930.1 - 0.011 15.8 2.2 0.025 14.6 2.2 1.7 1 0 0 1 1 1 0 WW domain RTC4 PF14474.6 KIK61932.1 - 1.6e-23 83.1 0.0 3.4e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Gate PF07670.14 KIK61933.1 - 1.8 8.9 6.8 27 5.1 6.8 2.4 1 1 0 1 1 1 0 Nucleoside recognition Trp_oprn_chp PF09534.10 KIK61934.1 - 0.046 13.5 1.5 0.086 12.6 1.5 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NACHT PF05729.12 KIK61935.1 - 9.3e-10 38.7 0.0 2.5e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61935.1 - 4.4e-08 33.7 0.0 7.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61935.1 - 1.9e-05 25.0 0.0 4.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK61935.1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK61935.1 - 0.0039 16.5 0.1 2.1 7.5 0.0 2.1 1 1 1 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.22 KIK61935.1 - 0.0061 16.9 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KIK61935.1 - 0.058 13.9 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIK61935.1 - 0.083 13.3 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK61935.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIK61935.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Glyco_transf_4 PF13439.6 KIK61937.1 - 0.095 12.7 0.2 0.1 12.6 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NACHT PF05729.12 KIK61939.1 - 3e-10 40.3 0.0 6.9e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61939.1 - 7.9e-09 36.1 0.0 9.9e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK61939.1 - 2.4e-05 24.4 0.0 3.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK61939.1 - 0.00013 22.2 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Nrf1_DNA-bind PF10491.9 KIK61939.1 - 0.0041 16.8 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 RNA_helicase PF00910.22 KIK61939.1 - 0.0049 17.2 0.0 0.0091 16.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA PF00004.29 KIK61939.1 - 0.024 15.1 0.0 0.052 14.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK61939.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK61939.1 - 0.19 10.9 1.1 4.9 6.3 0.2 2.4 1 1 2 3 3 3 0 KAP family P-loop domain APS_kinase PF01583.20 KIK61939.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase COE1_DBD PF16422.5 KIK61940.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain zf-MYND PF01753.18 KIK61942.1 - 0.23 11.6 15.8 1.3 9.1 4.0 2.7 2 1 0 2 2 2 0 MYND finger NACHT PF05729.12 KIK61945.1 - 5.6e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK61945.1 - 1e-05 26.0 0.0 2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK61945.1 - 2.9e-05 24.1 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK61945.1 - 0.00038 19.8 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 KAP family P-loop domain AAA_7 PF12775.7 KIK61945.1 - 0.00087 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KIK61945.1 - 0.00091 19.5 0.0 0.0078 16.5 0.0 2.3 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 KIK61945.1 - 0.001 19.5 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 KIK61945.1 - 0.0023 18.4 0.0 0.017 15.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK61945.1 - 0.0051 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Parvo_NS1 PF01057.17 KIK61945.1 - 0.023 13.8 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 KIK61945.1 - 0.03 14.3 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 KIK61945.1 - 0.052 13.7 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.6 KIK61945.1 - 0.075 12.7 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain OrgA_MxiK PF09482.10 KIK61945.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) AAA_19 PF13245.6 KIK61945.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK61945.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_mis_repair PF01119.19 KIK61945.1 - 0.17 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain NACHT PF05729.12 KIK61949.1 - 1.6e-07 31.4 0.2 9.3e-07 28.9 0.2 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61949.1 - 3.5e-07 30.7 0.0 6.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61949.1 - 0.0018 18.6 0.0 0.0052 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KIK61949.1 - 0.0018 17.6 0.1 0.27 10.4 0.0 2.1 1 1 1 2 2 2 2 KAP family P-loop domain ATPase_2 PF01637.18 KIK61949.1 - 0.006 16.5 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK61949.1 - 0.0082 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KIK61949.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK61949.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KIK61949.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KIK61949.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK61949.1 - 0.18 12.2 0.0 0.39 11.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RINGv PF12906.7 KIK61950.1 - 1.4e-17 63.5 7.7 1.9e-17 63.1 7.7 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIK61950.1 - 0.00044 20.5 9.5 0.00065 20.0 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KIK61950.1 - 0.0058 16.4 5.6 0.0097 15.7 5.6 1.4 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIK61950.1 - 0.035 14.2 4.8 0.056 13.5 4.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YyzF PF14116.6 KIK61950.1 - 0.046 13.7 4.3 3.2 7.9 0.1 2.2 2 0 0 2 2 2 0 YyzF-like protein DUF2695 PF10905.8 KIK61950.1 - 0.071 13.3 0.1 0.28 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2695) RecR PF02132.15 KIK61950.1 - 0.79 9.3 5.0 1.3 8.6 0.7 2.4 2 0 0 2 2 2 0 RecR protein zf-RING-like PF08746.11 KIK61950.1 - 1.6 9.1 9.4 3.1 8.2 9.4 1.6 1 1 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KIK61950.1 - 4.4 7.7 11.3 10 6.5 10.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain NACHT PF05729.12 KIK61953.1 - 9.3e-09 35.4 0.1 3e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61953.1 - 1.8e-07 31.7 0.1 3.4e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK61953.1 - 2.2e-05 24.5 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK61953.1 - 0.00093 19.5 0.0 0.0028 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK61953.1 - 0.0044 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK61953.1 - 0.0071 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.14 KIK61953.1 - 0.016 14.4 0.0 3.5 6.8 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.14 KIK61953.1 - 0.033 14.2 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIK61953.1 - 0.1 13.0 0.0 0.34 11.4 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_mis_repair PF01119.19 KIK61953.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain RINGv PF12906.7 KIK61955.1 - 0.00023 21.2 0.1 0.00036 20.6 0.1 1.3 1 0 0 1 1 1 1 RING-variant domain NACHT PF05729.12 KIK61956.1 - 1.1e-07 31.9 0.0 3.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61956.1 - 0.00012 22.5 0.0 0.00019 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61956.1 - 0.00026 21.3 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK61956.1 - 0.00047 20.1 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK61956.1 - 0.0042 16.4 0.8 0.096 11.9 0.1 2.0 1 1 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 KIK61956.1 - 0.0097 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 KIK61956.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KIK61956.1 - 0.019 15.4 0.0 0.056 13.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK61956.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK61956.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK61956.1 - 0.18 10.8 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KIK61957.1 - 4.7e-11 42.9 0.0 8.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61957.1 - 2.9e-06 27.8 0.1 6.1e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61957.1 - 7.2e-05 23.1 0.0 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK61957.1 - 0.0029 17.6 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK61957.1 - 0.0048 16.2 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain Parvo_NS1 PF01057.17 KIK61957.1 - 0.0063 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK61957.1 - 0.038 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ELYS PF13934.6 KIK61957.1 - 0.074 13.0 0.0 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 Nuclear pore complex assembly AAA PF00004.29 KIK61957.1 - 0.16 12.4 0.0 0.5 10.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Acetyltransf_1 PF00583.25 KIK61958.1 - 0.038 14.2 0.0 0.098 12.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family VMA21 PF09446.10 KIK61959.1 - 0.028 14.5 1.7 0.053 13.6 1.7 1.4 1 0 0 1 1 1 0 VMA21-like domain NACHT PF05729.12 KIK61960.1 - 6e-07 29.5 0.3 2.4e-06 27.6 0.3 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61960.1 - 8.3e-06 26.3 0.0 3.2e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61960.1 - 8e-05 22.9 0.0 0.00025 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK61960.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF257 PF03192.13 KIK61960.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 RNA_helicase PF00910.22 KIK61960.1 - 0.033 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KIK61960.1 - 0.093 12.7 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KIK61960.1 - 0.11 11.8 0.2 6.6 5.9 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 KIK61960.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK61960.1 - 0.15 11.6 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KIK61962.1 - 1e-10 42.3 0.1 1.9e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK61962.1 - 2e-09 37.6 0.3 6e-09 36.0 0.3 1.7 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK61962.1 - 0.00067 19.6 0.0 0.00097 19.1 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK61962.1 - 0.0013 19.0 0.0 0.0038 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Nrf1_DNA-bind PF10491.9 KIK61962.1 - 0.0052 16.5 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 RNA_helicase PF00910.22 KIK61962.1 - 0.018 15.5 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KIK61962.1 - 0.037 13.3 0.4 3.8 6.7 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.14 KIK61962.1 - 0.061 13.3 0.0 0.28 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIK61962.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK61962.1 - 0.066 12.9 0.1 0.18 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK61962.1 - 0.18 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain BRK PF07533.16 KIK61965.1 - 0.015 14.9 0.0 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 BRK domain Acetyltransf_1 PF00583.25 KIK61965.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK61965.1 - 0.18 12.2 0.0 0.49 10.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dicty_REP PF05086.12 KIK61967.1 - 0.3 9.0 1.5 0.43 8.5 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pheromone PF08015.11 KIK61967.1 - 2 9.5 8.3 18 6.5 0.3 3.2 3 0 0 3 3 3 0 Fungal mating-type pheromone Acetyltransf_1 PF00583.25 KIK61968.1 - 6.8e-08 32.8 0.0 9.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK61968.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK61968.1 - 4.9e-05 23.7 0.0 8.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK61968.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein DUF4672 PF15716.5 KIK61969.1 - 0.067 12.8 0.4 0.089 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) TFIIE-A_C PF11521.8 KIK61969.1 - 4.8 7.6 7.0 9.6 6.6 7.0 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Smr PF01713.21 KIK61970.1 - 1.6e-08 34.8 0.4 8.6e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 KIK61970.1 - 6.1e-08 32.9 6.0 1.1e-07 32.1 6.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DUF2015 PF09435.10 KIK61971.1 - 1.4e-36 124.7 0.1 1.7e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FeoA PF04023.14 KIK61977.1 - 0.085 13.1 0.1 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 FeoA domain Chromo_shadow PF01393.19 KIK61978.1 - 8e-18 64.3 0.6 2e-15 56.6 0.1 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KIK61978.1 - 6.2e-10 38.8 0.6 6.2e-10 38.8 0.6 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain SET_assoc PF11767.8 KIK61978.1 - 0.11 12.2 0.2 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SOBP PF15279.6 KIK61978.1 - 0.22 12.1 5.1 0.29 11.7 5.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MCM_bind PF09739.9 KIK61978.1 - 2.3 6.6 11.8 3.1 6.1 11.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RRM_1 PF00076.22 KIK61979.1 - 3.6e-15 55.5 0.1 5.4e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK61979.1 - 0.056 13.5 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KIK61979.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-MYND PF01753.18 KIK61980.1 - 2.4e-08 33.9 12.1 4.7e-08 33.0 12.1 1.5 1 0 0 1 1 1 1 MYND finger Vfa1 PF08432.10 KIK61980.1 - 1.1 9.5 3.6 1.6 9.1 3.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-Mss51 PF13824.6 KIK61980.1 - 5 7.3 9.8 66 3.7 10.2 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.7 KIK61981.1 - 0.00066 19.5 3.6 0.00079 19.3 1.7 2.3 2 0 0 2 2 2 1 F-box-like BAR_3_WASP_bdg PF10456.9 KIK61981.1 - 0.099 12.1 0.2 3.6 7.0 0.0 2.4 3 0 0 3 3 3 0 WASP-binding domain of Sorting nexin protein LRR_4 PF12799.7 KIK61981.1 - 1.7 9.1 6.5 3.8 8.1 0.5 4.6 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK61981.1 - 5.1 7.1 8.6 1.7 8.6 3.1 3.0 3 0 0 3 3 3 0 F-box domain RINGv PF12906.7 KIK61982.1 - 5.7e-16 58.4 7.7 1.1e-15 57.5 7.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIK61982.1 - 0.023 15.0 9.5 0.039 14.3 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KIK61982.1 - 1.8 8.4 7.9 3.2 7.6 7.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIK61982.1 - 2 8.5 4.7 3.9 7.6 4.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIK61982.1 - 7 6.6 6.8 12 5.8 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.12 KIK61983.1 - 3.2e-07 30.4 0.1 1.6e-06 28.1 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61983.1 - 1.8e-06 28.5 0.0 7.8e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61983.1 - 0.0023 18.2 0.0 0.015 15.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KIK61983.1 - 0.0027 17.7 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK61983.1 - 0.01 16.2 0.0 0.032 14.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK61983.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 KIK61983.1 - 0.58 9.9 2.8 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III, delta subunit NACHT PF05729.12 KIK61985.1 - 0.006 16.5 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain COE1_DBD PF16422.5 KIK61985.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain G-alpha PF00503.20 KIK61988.1 - 1.6e-103 346.6 0.0 1.9e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK61988.1 - 6e-05 22.6 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Dimer_Tnp_hAT PF05699.14 KIK61989.1 - 3.5e-08 33.1 0.2 3.8e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ALMT PF11744.8 KIK61990.1 - 1.1 8.0 3.2 1.5 7.5 3.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CagY_I PF14585.6 KIK61991.1 - 0.18 11.9 1.8 8.7 6.5 0.1 2.5 2 0 0 2 2 2 0 CagY type 1 repeat Retrotran_gag_2 PF14223.6 KIK61992.1 - 1.8e-07 30.9 0.4 2.5e-07 30.4 0.4 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NACHT PF05729.12 KIK61993.1 - 3.4e-08 33.6 0.2 2.1e-07 31.0 0.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61993.1 - 1.4e-07 32.1 0.0 4.4e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK61993.1 - 0.00033 20.9 0.0 0.0016 18.7 0.0 2.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK61993.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK61993.1 - 0.023 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KIK61993.1 - 0.11 12.2 0.1 0.43 10.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KIK61995.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Pro-kuma_activ PF09286.11 KIK61996.1 - 3.2e-36 124.7 1.4 1.1e-35 122.9 0.4 2.3 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK61996.1 - 2.6e-05 23.6 1.0 4.7e-05 22.8 0.3 1.7 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.11 KIK61997.1 - 4.5e-31 108.0 1.4 6e-31 107.6 0.5 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK61997.1 - 1.2e-05 24.8 3.3 2.2e-05 23.9 3.3 1.4 1 0 0 1 1 1 1 Subtilase family NACHT PF05729.12 KIK61998.1 - 3.1e-10 40.2 0.0 7.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK61998.1 - 5.1e-08 33.5 0.1 1.4e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK61998.1 - 4.9e-06 26.6 0.0 8.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK61998.1 - 0.0012 19.1 0.0 0.0057 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK61998.1 - 0.009 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.14 KIK61998.1 - 0.042 13.1 0.7 5.6 6.1 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain AAA PF00004.29 KIK61998.1 - 0.057 13.8 0.0 0.18 12.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK61998.1 - 0.092 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK61998.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KIK61998.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KIK61998.1 - 0.17 12.4 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Lyase_8 PF02278.18 KIK62001.1 - 6.8e-66 222.4 1.2 1.1e-65 221.7 1.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KIK62001.1 - 3.5e-23 82.0 0.0 6.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KIK62001.1 - 3e-07 30.8 0.0 8.8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain F-box-like PF12937.7 KIK62002.1 - 5.2e-08 32.7 1.8 1.7e-07 31.0 1.8 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK62003.1 - 4.4e-08 32.9 0.6 1.2e-07 31.5 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK62004.1 - 8.4e-09 35.2 2.0 2.2e-08 33.9 2.0 1.8 1 0 0 1 1 1 1 F-box-like PTS_2-RNA PF01885.16 KIK62005.1 - 1.2e-65 221.0 0.0 1.4e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ribosomal_L16 PF00252.18 KIK62006.1 - 9.5e-46 155.1 0.0 1.2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAS_9 PF13426.7 KIK62007.1 - 5.5e-25 87.6 0.0 7.9e-15 55.0 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 KIK62007.1 - 4.9e-18 65.2 0.0 3.3e-08 33.7 0.0 4.3 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 KIK62007.1 - 1.7e-13 50.5 0.0 0.00027 20.9 0.0 4.7 5 0 0 5 5 5 3 PAS fold PAS_4 PF08448.10 KIK62007.1 - 7.3e-09 35.9 0.0 2.2e-05 24.7 0.0 3.6 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KIK62007.1 - 0.00021 21.2 0.0 0.046 13.8 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 KIK62007.1 - 0.0013 18.8 0.0 0.46 10.6 0.0 2.9 3 0 0 3 3 3 1 PAS domain DLH PF01738.18 KIK62008.1 - 3.8e-23 82.2 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KIK62008.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIK62008.1 - 0.0051 16.3 0.2 0.32 10.5 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIK62008.1 - 0.085 12.5 0.0 12 5.4 0.0 2.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold F-box-like PF12937.7 KIK62009.1 - 1.1e-07 31.7 1.6 2.9e-07 30.3 1.6 1.8 1 1 0 1 1 1 1 F-box-like FEZ PF07763.13 KIK62009.1 - 0.066 13.0 0.0 0.091 12.5 0.0 1.1 1 0 0 1 1 1 0 FEZ-like protein F-box-like PF12937.7 KIK62010.1 - 1.4e-06 28.0 1.2 5.5e-06 26.2 1.2 2.1 1 1 0 1 1 1 1 F-box-like DUF2730 PF10805.8 KIK62010.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) F-box-like PF12937.7 KIK62011.1 - 9.6e-06 25.4 0.1 2.6e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 F-box-like Glutaredoxin PF00462.24 KIK62012.1 - 1.2e-16 60.6 0.0 1.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Herpes_ori_bp PF02399.15 KIK62012.1 - 0.19 9.7 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein zf-DNL PF05180.12 KIK62013.1 - 1.2e-29 102.0 0.1 1.7e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 KIK62013.1 - 1.3 9.0 4.6 9.1 6.3 0.4 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain adh_short PF00106.25 KIK62014.1 - 3.2e-37 127.9 0.0 3.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK62014.1 - 3.5e-30 105.3 0.0 4.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK62014.1 - 1e-11 45.1 1.6 4.4e-11 43.0 1.6 2.1 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KIK62014.1 - 0.2 10.6 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIK62015.1 - 1.4e-36 125.8 0.1 1.7e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK62015.1 - 8.4e-28 97.5 0.1 1.1e-27 97.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK62015.1 - 3.7e-10 40.0 1.2 1e-09 38.6 1.2 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KIK62015.1 - 0.033 13.2 0.0 0.1 11.6 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MCPsignal PF00015.21 KIK62015.1 - 0.048 13.5 0.4 0.071 12.9 0.4 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2183 PF09949.9 KIK62022.1 - 0.00011 22.4 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF1806 PF08830.10 KIK62023.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1806) BC10 PF06726.12 KIK62026.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 DUF1493 PF07377.12 KIK62030.1 - 0.099 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2183 PF09949.9 KIK62033.1 - 7.6e-24 83.9 0.3 2.4e-14 53.4 0.0 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2183) zf-primase PF09329.11 KIK62034.1 - 0.38 10.6 4.0 0.76 9.6 0.1 2.4 2 0 0 2 2 2 0 Primase zinc finger FOXP-CC PF16159.5 KIK62034.1 - 2.2 9.0 7.0 11 6.8 2.6 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain Zn_clus PF00172.18 KIK62035.1 - 9.2e-07 28.9 5.2 2.4e-06 27.6 5.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Doppel PF11466.8 KIK62037.1 - 0.091 12.4 3.7 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Prion-like protein Doppel Brix PF04427.18 KIK62038.1 - 1.2e-10 41.8 0.0 1.9e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Brix PF04427.18 KIK62039.1 - 0.00014 22.0 0.0 0.00042 20.5 0.0 1.7 1 1 0 1 1 1 1 Brix domain zf-TAZ PF02135.16 KIK62040.1 - 0.14 12.6 1.9 0.27 11.7 1.9 1.5 1 0 0 1 1 1 0 TAZ zinc finger zf-C2H2_4 PF13894.6 KIK62040.1 - 1.6 9.7 6.8 19 6.4 2.7 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK62040.1 - 2.3 8.9 6.0 11 6.7 2.6 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF737 PF05300.11 KIK62042.1 - 0.018 15.4 1.0 0.021 15.2 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PGC7_Stella PF15549.6 KIK62042.1 - 0.072 13.1 1.7 0.093 12.7 1.7 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain FAM199X PF15814.5 KIK62042.1 - 0.21 10.6 3.3 0.27 10.2 3.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X WRC PF08879.10 KIK62046.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 WRC zf-C2H2_4 PF13894.6 KIK62046.1 - 2.8 9.0 9.0 2.6 9.1 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger WRC PF08879.10 KIK62048.1 - 0.068 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 WRC zf-TAZ PF02135.16 KIK62048.1 - 0.11 13.0 1.6 0.2 12.1 1.6 1.4 1 0 0 1 1 1 0 TAZ zinc finger zf-C2H2_4 PF13894.6 KIK62048.1 - 1.3 10.1 6.9 18 6.5 2.7 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK62048.1 - 2.2 9.0 5.8 11 6.8 2.5 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-primase PF09329.11 KIK62048.1 - 8.9 6.2 6.6 3.4 7.6 0.1 2.6 2 1 0 2 2 2 0 Primase zinc finger Brix PF04427.18 KIK62049.1 - 1.4e-30 106.9 0.0 2e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.7 KIK62050.1 - 4.9e-05 23.1 3.8 0.0002 21.2 3.8 2.0 1 1 0 1 1 1 1 F-box-like Zn_clus PF00172.18 KIK62051.1 - 1.6e-06 28.1 5.2 3.1e-06 27.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK62051.1 - 0.01 14.9 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain She9_MDM33 PF05546.11 KIK62053.1 - 5.6e-74 248.2 9.2 9e-74 247.6 9.2 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family DUF16 PF01519.16 KIK62053.1 - 0.0018 18.8 9.1 0.0025 18.3 0.9 2.4 2 0 0 2 2 2 1 Protein of unknown function DUF16 Glyco_hydro_67N PF03648.14 KIK62053.1 - 0.0026 18.0 0.2 0.009 16.3 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Put_Phosphatase PF06888.12 KIK62053.1 - 0.12 11.8 0.5 9.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Putative Phosphatase DUF948 PF06103.11 KIK62053.1 - 0.14 12.5 5.5 0.068 13.4 1.9 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 KIK62053.1 - 0.47 10.8 6.3 1.2 9.4 2.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KIK62053.1 - 0.81 9.7 7.0 0.27 11.3 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SurA_N_2 PF13623.6 KIK62053.1 - 2.6 7.9 7.4 1.3 8.9 0.3 3.1 3 0 0 3 3 3 0 SurA N-terminal domain NPV_P10 PF05531.12 KIK62053.1 - 3.7 8.1 6.6 3.7 8.1 2.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NUDIX PF00293.28 KIK62054.1 - 2.3e-09 37.4 0.1 3.3e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain OPT PF03169.15 KIK62055.1 - 3e-152 508.4 50.7 9.3e-96 321.8 30.0 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein DUF2370 PF10176.9 KIK62055.1 - 0.46 10.1 3.3 0.83 9.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Golgin_A5 PF09787.9 KIK62056.1 - 0.013 15.0 1.5 0.016 14.7 1.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 PTS_2-RNA PF01885.16 KIK62057.1 - 4.2e-10 40.0 0.0 4.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family HIG_1_N PF04588.13 KIK62058.1 - 5.1e-16 58.6 0.4 7.2e-16 58.2 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Glyco_hydro_47 PF01532.20 KIK62059.1 - 7.8e-142 473.4 0.0 9.1e-142 473.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 F-box-like PF12937.7 KIK62060.1 - 0.00011 22.0 6.0 0.00081 19.2 6.0 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK62061.1 - 2.3e-05 24.2 4.5 0.00015 21.6 4.5 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK62061.1 - 0.19 11.6 3.0 3.8 7.5 0.1 2.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK62062.1 - 0.00011 22.0 5.4 0.00033 20.5 5.4 1.8 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK62063.1 - 0.00026 20.8 6.7 0.0014 18.5 6.7 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK62065.1 - 2e-05 24.4 3.3 7.1e-05 22.6 3.3 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK62066.1 - 2.6e-05 24.0 7.0 0.00017 21.4 7.0 2.4 1 1 0 1 1 1 1 F-box-like YukD PF08817.10 KIK62066.1 - 0.12 13.1 0.0 0.87 10.3 0.0 2.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD F-box-like PF12937.7 KIK62067.1 - 3.9e-06 26.7 3.6 3.5e-05 23.6 3.6 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK62067.1 - 0.14 12.1 3.6 3.1 7.8 0.2 2.5 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK62069.1 - 1.1e-06 28.4 0.3 2.6e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 KIK62070.1 - 0.00014 21.7 0.6 0.32 11.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK62070.1 - 0.0039 17.4 0.3 0.21 11.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TMEM119 PF15724.5 KIK62070.1 - 0.031 14.3 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 TMEM119 family TPR_1 PF00515.28 KIK62070.1 - 0.096 12.5 0.4 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK62070.1 - 0.099 12.3 0.1 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 TPR repeat adh_short PF00106.25 KIK62073.1 - 5.4e-35 120.6 0.0 6.6e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK62073.1 - 4.8e-26 91.8 0.0 5.8e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK62073.1 - 4.5e-08 33.2 0.1 1.2e-07 31.8 0.1 1.6 1 1 0 1 1 1 1 KR domain RA PF00788.23 KIK62074.1 - 3e-14 53.4 0.1 4.3e-12 46.5 0.0 3.4 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KIK62074.1 - 2.3e-07 30.3 0.1 2.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIK62074.1 - 0.0028 17.5 1.0 0.0086 15.9 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain Par3_HAL_N_term PF12053.8 KIK62074.1 - 0.015 15.5 0.4 0.88 9.8 0.0 2.9 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins NdhM PF10664.9 KIK62074.1 - 0.13 12.5 1.6 0.76 10.1 0.1 2.8 2 1 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M CbiM PF01891.16 KIK62076.1 - 0.15 11.8 6.0 0.22 11.3 6.0 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Flavin_Reduct PF01613.18 KIK62078.1 - 3e-06 27.4 0.1 0.016 15.2 0.3 2.0 1 1 1 2 2 2 2 Flavin reductase like domain Flavin_Reduct PF01613.18 KIK62079.1 - 8.1e-32 110.4 0.1 9.6e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_76 PF03663.14 KIK62081.1 - 5.1e-05 23.0 0.0 0.00022 20.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.14 KIK62082.1 - 1.5e-13 51.0 4.5 3.2e-12 46.6 0.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 MFS_1 PF07690.16 KIK62083.1 - 1.9e-31 109.3 35.8 2.4e-30 105.6 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_47 PF01532.20 KIK62084.1 - 1e-141 473.0 0.0 1.2e-141 472.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1563 PF07599.11 KIK62084.1 - 4 7.6 5.5 5.3 7.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) Sds3 PF08598.11 KIK62085.1 - 5.9e-05 23.2 3.6 0.00019 21.5 3.6 1.8 1 1 0 1 1 1 1 Sds3-like Ank_2 PF12796.7 KIK62086.1 - 2.2e-28 98.6 1.2 1.1e-13 51.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK62086.1 - 1.6e-26 92.3 0.6 1.8e-11 44.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK62086.1 - 1.2e-21 76.2 5.3 3.1e-05 24.2 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK62086.1 - 1.2e-21 76.4 1.5 5e-06 26.7 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK62086.1 - 2.2e-20 70.6 0.2 0.00042 20.5 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat CDCA PF18484.1 KIK62086.1 - 0.045 13.6 0.2 0.12 12.2 0.0 1.7 1 1 1 2 2 2 0 Cadmium carbonic anhydrase repeat Ank_2 PF12796.7 KIK62087.1 - 2.7e-28 98.4 1.4 1.3e-13 51.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK62087.1 - 1.8e-26 92.2 0.6 2e-11 44.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK62087.1 - 1.5e-21 76.2 1.5 5.5e-06 26.6 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KIK62087.1 - 1.5e-21 75.8 5.3 3.4e-05 24.1 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KIK62087.1 - 2.8e-20 70.3 0.2 0.00045 20.4 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat CDCA PF18484.1 KIK62087.1 - 0.049 13.5 0.2 0.14 12.0 0.1 1.7 1 1 1 2 2 2 0 Cadmium carbonic anhydrase repeat Ank_4 PF13637.6 KIK62088.1 - 5.2e-29 100.2 0.9 2.6e-14 53.4 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK62088.1 - 7.3e-29 100.2 2.4 3.2e-14 53.3 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK62088.1 - 1.4e-27 94.8 6.3 4.5e-06 26.9 0.3 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KIK62088.1 - 9.3e-27 90.2 0.9 8.9e-06 25.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK62088.1 - 6.5e-23 80.5 4.7 2.6e-05 24.4 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) HTH_38 PF13936.6 KIK62088.1 - 0.036 13.8 0.0 0.49 10.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M73 PF12389.8 KIK62088.1 - 0.07 13.0 0.1 4.2 7.1 0.0 2.2 2 1 0 2 2 2 0 Camelysin metallo-endopeptidase Ank_4 PF13637.6 KIK62089.1 - 5.3e-44 148.0 8.1 8.7e-14 51.7 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK62089.1 - 9.4e-29 99.8 0.6 2.8e-16 59.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK62089.1 - 4.4e-25 87.0 4.3 5.8e-07 29.7 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KIK62089.1 - 7.5e-24 81.2 1.0 1.4e-05 25.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KIK62089.1 - 3e-20 72.0 6.5 7.4e-09 35.7 0.1 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) ANT PF03374.14 KIK62089.1 - 0.0031 17.8 0.0 4.6 7.6 0.0 2.9 1 1 2 3 3 3 1 Phage antirepressor protein KilAC domain Polyoma_agno PF01736.16 KIK62089.1 - 0.14 11.9 0.0 4.5 7.1 0.0 2.6 1 1 2 3 3 3 0 Polyomavirus agnoprotein RicinB_lectin_2 PF14200.6 KIK62091.1 - 1e-15 58.2 11.0 2.3e-06 28.3 3.3 2.8 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK62091.1 - 0.0014 18.8 0.0 0.005 17.1 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain BcrAD_BadFG PF01869.20 KIK62091.1 - 0.021 14.3 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HCBP_related PF06594.11 KIK62091.1 - 0.065 13.2 0.9 1.1 9.2 0.6 2.4 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain SH3_1 PF00018.28 KIK62093.1 - 8.9e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK62093.1 - 5.6e-05 22.9 0.2 0.00067 19.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_10 PF17902.1 KIK62093.1 - 0.18 11.9 0.1 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 SH3 domain Goodbye PF17109.5 KIK62096.1 - 7.5e-11 42.5 0.2 1e-10 42.1 0.2 1.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain FliN_N PF16973.5 KIK62096.1 - 0.067 13.0 2.4 0.085 12.7 0.8 2.0 1 1 1 2 2 2 0 Flagellar motor switch protein FliN N-terminal WD40 PF00400.32 KIK62100.1 - 2e-23 82.2 10.4 4.3e-09 36.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62100.1 - 9.5e-14 51.5 0.0 0.0012 19.1 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62100.1 - 5.1e-07 29.5 0.1 0.33 10.9 0.0 3.6 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK62100.1 - 5.4e-06 26.4 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK62100.1 - 1.2e-05 25.8 0.0 3.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK62100.1 - 6.6e-05 23.3 0.1 0.00096 19.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK62100.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KIK62100.1 - 0.053 14.1 0.1 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK62100.1 - 0.063 12.4 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KIK62100.1 - 0.064 12.5 0.0 0.23 10.7 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin HMD PF03201.16 KIK62100.1 - 0.083 13.1 0.2 8.7 6.6 0.0 2.9 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase IstB_IS21 PF01695.17 KIK62100.1 - 0.13 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIK62100.1 - 0.15 12.3 0.0 0.8 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain Goodbye PF17109.5 KIK62101.1 - 1.5e-07 31.9 0.0 2.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain IF4E PF01652.18 KIK62101.1 - 0.0025 17.6 0.2 0.0032 17.3 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1031 PF06275.11 KIK62101.1 - 0.059 13.6 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF1708 PF08101.11 KIK62103.1 - 9.1e-05 21.8 0.0 0.021 14.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1708) S_2TMBeta PF18153.1 KIK62105.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain WD40 PF00400.32 KIK62106.1 - 9.1e-48 159.2 11.5 3.4e-10 40.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62106.1 - 2.8e-18 66.0 0.0 0.0016 18.7 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62106.1 - 9.4e-08 31.8 4.2 1.1 9.3 0.0 4.7 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK62106.1 - 2e-07 31.5 0.0 5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK62106.1 - 6.7e-06 26.6 0.1 0.00012 22.6 0.1 3.0 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 KIK62106.1 - 0.00016 20.7 0.0 0.53 9.2 0.0 3.8 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK62106.1 - 0.0019 18.2 0.2 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KIK62106.1 - 0.0039 17.7 0.1 0.021 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK62106.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK62106.1 - 0.0071 15.6 0.2 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 KIK62106.1 - 0.016 14.4 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KIK62106.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 KIK62106.1 - 0.038 14.0 0.4 0.071 13.1 0.2 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK62106.1 - 0.043 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytochrom_D1 PF02239.16 KIK62106.1 - 0.059 11.9 0.0 0.21 10.1 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 KIK62106.1 - 0.061 11.6 0.0 46 2.1 0.0 3.5 3 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Fim-adh_lectin PF09222.10 KIK62106.1 - 0.063 12.8 0.1 0.32 10.5 0.0 2.1 1 1 0 2 2 2 0 Fimbrial adhesin F17-AG, lectin domain PQQ PF01011.21 KIK62106.1 - 0.088 12.8 0.0 66 3.7 0.0 4.3 5 0 0 5 5 5 0 PQQ enzyme repeat Proteasome_A_N PF10584.9 KIK62106.1 - 0.12 12.1 2.7 64 3.4 0.1 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature ATPase PF06745.13 KIK62106.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 KaiC WD40 PF00400.32 KIK62111.1 - 3.4e-32 109.9 10.6 7.8e-11 42.4 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62111.1 - 2.6e-12 46.8 0.1 0.0012 19.1 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62111.1 - 9.1e-08 31.9 0.3 0.25 11.3 0.0 3.5 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK62111.1 - 2.4e-06 26.7 0.1 0.17 10.8 0.0 3.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK62111.1 - 0.0009 17.7 0.0 0.028 12.8 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK62111.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 WD40-like domain Proteasome_A_N PF10584.9 KIK62111.1 - 0.057 13.1 1.1 31 4.3 0.0 3.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DHFR_2 PF06442.11 KIK62111.1 - 0.12 12.2 0.1 15 5.5 0.0 2.9 1 1 2 3 3 3 0 R67 dihydrofolate reductase AAA_16 PF13191.6 KIK62112.1 - 0.00035 21.0 0.0 0.0004 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK62112.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK62112.1 - 0.0037 16.6 0.0 0.0067 15.7 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KIK62112.1 - 0.0062 17.1 0.0 0.009 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK62112.1 - 0.014 14.5 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIK62112.1 - 0.028 14.4 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 KIK62112.1 - 0.028 13.6 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.14 KIK62112.1 - 0.04 13.1 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase IstB_IS21 PF01695.17 KIK62112.1 - 0.043 13.5 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIK62112.1 - 0.044 14.1 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK62112.1 - 0.096 13.1 0.1 0.13 12.7 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK62112.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KIK62112.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK62112.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Goodbye PF17109.5 KIK62113.1 - 1.3e-09 38.5 0.0 7.9e-09 36.0 0.0 2.2 2 1 0 2 2 2 1 fungal STAND N-terminal Goodbye domain WD40 PF00400.32 KIK62116.1 - 5.4e-126 406.8 73.2 1.2e-09 38.6 0.4 15.2 16 0 0 16 16 16 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62116.1 - 4.7e-52 174.2 11.0 0.0017 18.6 0.0 14.1 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62116.1 - 1.9e-27 94.5 16.8 0.49 10.4 0.0 14.4 15 0 0 15 15 15 9 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK62116.1 - 2.3e-19 69.2 0.0 0.67 8.2 0.0 12.2 7 3 1 10 10 10 7 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK62116.1 - 9.8e-14 51.0 9.5 1.7 7.5 0.0 12.5 5 3 9 14 14 14 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK62116.1 - 8.8e-10 38.4 0.0 1.4 8.2 0.0 8.9 7 3 5 12 12 12 2 WD40-like domain Proteasome_A_N PF10584.9 KIK62116.1 - 8.6e-06 25.3 19.1 11 5.8 0.1 11.1 12 0 0 12 12 12 1 Proteasome subunit A N-terminal signature PQQ PF01011.21 KIK62116.1 - 1.7e-05 24.5 0.0 95 3.2 0.0 8.2 9 0 0 9 9 9 0 PQQ enzyme repeat DHFR_2 PF06442.11 KIK62116.1 - 0.0065 16.3 4.5 14 5.6 0.0 6.1 8 0 0 8 8 8 1 R67 dihydrofolate reductase Me-amine-dh_H PF06433.11 KIK62116.1 - 0.13 11.1 0.0 16 4.3 0.0 3.9 4 1 1 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 KIK62117.1 - 0.00014 22.3 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK62117.1 - 0.00068 19.2 0.0 0.00089 18.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK62117.1 - 0.0023 17.2 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KIK62117.1 - 0.0039 17.7 0.0 0.0085 16.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KIK62117.1 - 0.0049 16.1 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KIK62117.1 - 0.0057 16.4 0.1 0.0076 16.0 0.1 1.3 1 1 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.22 KIK62117.1 - 0.0058 15.8 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.15 KIK62117.1 - 0.023 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 KIK62117.1 - 0.026 13.7 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA PF00004.29 KIK62117.1 - 0.084 13.3 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK62117.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK62117.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NifW PF03206.14 KIK62117.1 - 0.13 12.8 0.1 0.65 10.6 0.0 2.0 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Torsin PF06309.11 KIK62117.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Torsin Goodbye PF17109.5 KIK62118.1 - 0.0056 17.1 0.0 0.0092 16.4 0.0 1.3 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain DUF2829 PF11195.8 KIK62118.1 - 0.099 12.9 0.4 0.16 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2829) DUF3352 PF11832.8 KIK62118.1 - 0.11 11.1 0.2 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) STAT2_C PF12188.8 KIK62118.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Spore_SspJ PF09575.10 KIK62118.1 - 0.18 12.2 4.4 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) DUF2738 PF10927.8 KIK62120.1 - 0.046 12.8 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2738) Glyco_hydro_92 PF07971.12 KIK62122.1 - 7.9e-126 420.7 0.0 9.3e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK62122.1 - 1.2e-56 192.3 0.6 3.6e-56 190.7 0.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_92 PF07971.12 KIK62123.1 - 6.6e-127 424.2 0.0 7.7e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK62123.1 - 2.5e-55 187.9 0.6 4.8e-55 187.1 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_79C PF16862.5 KIK62124.1 - 3.5e-13 50.3 0.0 7.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain MFS_1 PF07690.16 KIK62125.1 - 6.2e-27 94.4 25.3 6.2e-27 94.4 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GFA PF04828.14 KIK62127.1 - 4.1e-18 65.5 0.0 6.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DpnI PF06044.12 KIK62127.1 - 0.29 10.8 1.5 0.56 9.8 1.5 1.4 1 1 0 1 1 1 0 Dam-replacing family GFA PF04828.14 KIK62128.1 - 2.8e-19 69.3 0.2 4.8e-19 68.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.14 KIK62129.1 - 1.5e-17 63.7 0.2 2.3e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ECH_1 PF00378.20 KIK62130.1 - 1.8e-32 112.7 0.0 2.2e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK62130.1 - 9.8e-15 54.9 0.0 5.1e-14 52.5 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF2927 PF11150.8 KIK62130.1 - 0.078 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) Mito_carr PF00153.27 KIK62131.1 - 2.3e-58 194.1 2.4 1.4e-20 73.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 KIK62131.1 - 1.3 9.0 4.4 9 6.3 0.2 2.8 3 0 0 3 3 3 0 Colicin V production protein PsiF_repeat PF07769.14 KIK62133.1 - 0.15 12.0 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 psiF repeat WD40 PF00400.32 KIK62138.1 - 1.2e-121 393.0 31.4 7.7e-10 39.2 0.0 12.3 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62138.1 - 8.3e-51 170.2 2.1 0.00073 19.8 0.0 12.3 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62138.1 - 4.3e-33 112.6 1.0 0.17 11.9 0.0 12.4 12 0 0 12 12 12 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK62138.1 - 5.7e-22 78.1 0.5 0.26 10.2 0.0 11.5 1 1 10 12 12 12 6 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK62138.1 - 3.9e-12 46.5 0.0 0.02 14.8 0.0 5.1 1 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A DHFR_2 PF06442.11 KIK62138.1 - 2e-10 40.4 2.4 0.21 11.5 0.0 8.1 6 2 3 9 9 8 1 R67 dihydrofolate reductase Frtz PF11768.8 KIK62138.1 - 2.7e-09 35.9 0.0 1 7.6 0.0 8.2 5 3 1 7 7 7 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK62138.1 - 1.3e-06 28.0 0.0 38 3.5 0.0 8.2 6 4 4 10 10 10 0 WD40-like domain PQQ_2 PF13360.6 KIK62138.1 - 1.7e-06 27.8 9.0 0.072 12.7 0.1 4.2 1 1 3 4 4 4 3 PQQ-like domain Proteasome_A_N PF10584.9 KIK62138.1 - 1e-05 25.1 18.4 40 4.0 0.1 10.6 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KIK62138.1 - 1.1e-05 25.7 0.6 31 5.2 0.1 6.4 7 0 0 7 7 7 0 PQQ-like domain Nup160 PF11715.8 KIK62138.1 - 6.8e-05 21.7 0.0 29 3.1 0.0 6.5 7 1 1 8 8 8 0 Nucleoporin Nup120/160 AAA_16 PF13191.6 KIK62138.1 - 7.9e-05 23.1 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CHAP PF05257.16 KIK62138.1 - 0.0001 22.8 13.9 11 6.6 0.1 8.1 2 2 4 7 7 7 0 CHAP domain NACHT PF05729.12 KIK62138.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain PQQ PF01011.21 KIK62138.1 - 0.00034 20.4 0.0 16 5.7 0.0 7.2 10 0 0 10 10 9 0 PQQ enzyme repeat AAA PF00004.29 KIK62138.1 - 0.0011 19.4 0.1 0.0043 17.5 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK62138.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KIK62138.1 - 0.019 14.1 0.0 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KIK62138.1 - 0.019 15.5 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_gyraseB_C PF00986.21 KIK62138.1 - 0.042 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus DUF4672 PF15716.5 KIK62143.1 - 0.089 12.4 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) Ank_2 PF12796.7 KIK62144.1 - 3.2e-17 62.9 16.0 1.5e-09 38.3 3.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK62144.1 - 2.2e-11 44.0 1.9 5.7e-05 23.6 0.0 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK62144.1 - 5.5e-10 38.6 6.5 0.36 11.5 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 KIK62144.1 - 4.6e-09 36.4 0.1 1.6e-08 34.7 0.0 2.0 2 1 0 2 2 2 1 NACHT domain Ank PF00023.30 KIK62144.1 - 2.3e-07 30.9 13.4 0.4 11.2 0.2 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK62144.1 - 5.3e-05 23.4 5.5 0.039 14.3 0.4 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KIK62144.1 - 0.00079 19.8 0.0 0.0082 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KIK62144.1 - 0.0018 17.6 0.1 0.015 14.5 0.1 2.4 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KIK62144.1 - 0.0037 16.5 0.0 0.0064 15.8 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain DUF2075 PF09848.9 KIK62144.1 - 0.0065 15.8 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KIK62144.1 - 0.0068 16.8 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KIK62144.1 - 0.0072 16.4 0.0 0.1 12.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 KIK62144.1 - 0.059 13.6 0.2 0.52 10.6 0.0 2.6 4 0 0 4 4 4 0 AAA domain Ank_2 PF12796.7 KIK62147.1 - 6.5e-56 186.9 71.8 8.1e-12 45.6 4.4 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK62147.1 - 4e-44 148.5 19.7 4.5e-07 30.3 0.2 10.9 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 KIK62147.1 - 3.2e-32 109.5 41.4 0.0035 17.7 0.2 11.3 10 1 1 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 KIK62147.1 - 2e-29 98.3 25.8 0.026 15.1 0.1 11.6 12 0 0 12 12 11 9 Ankyrin repeat Ank_5 PF13857.6 KIK62147.1 - 3.8e-18 65.3 28.2 0.004 17.4 0.3 8.9 5 3 4 9 9 9 8 Ankyrin repeats (many copies) DUF3447 PF11929.8 KIK62147.1 - 2.3e-09 37.1 0.3 2.8 8.0 0.1 6.4 3 3 2 7 7 7 2 Domain of unknown function (DUF3447) YajC PF02699.15 KIK62147.1 - 5.1e-05 23.1 19.2 0.35 10.8 0.1 7.7 2 2 7 9 9 9 2 Preprotein translocase subunit Mic1 PF07035.12 KIK62147.1 - 0.0026 17.5 8.9 17 5.1 0.1 7.1 4 3 3 8 8 8 0 Colon cancer-associated protein Mic1-like DUF240 PF03086.14 KIK62147.1 - 0.0033 17.3 0.1 7.2 6.6 0.0 4.7 5 1 1 6 6 6 1 Domain of unknown function (DUF240) UDPG_MGDP_dh_C PF03720.15 KIK62147.1 - 0.066 13.6 2.8 51 4.4 0.0 6.1 6 1 1 7 7 7 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UTP15_C PF09384.10 KIK62147.1 - 0.078 12.7 0.8 59 3.3 0.0 4.5 4 1 2 6 6 6 0 UTP15 C terminal TbpB_B_D PF01298.18 KIK62147.1 - 0.26 11.7 19.1 0.18 12.2 0.9 4.8 2 2 4 6 6 6 0 C-lobe and N-lobe beta barrels of Tf-binding protein B DUF4424 PF14415.6 KIK62147.1 - 1.9 7.7 5.4 46 3.1 0.0 3.9 2 1 3 5 5 5 0 Domain of unknown function (DUF4424) NdhO PF11910.8 KIK62147.1 - 2.4 8.4 3.7 59 3.9 0.0 4.2 4 2 1 5 5 5 0 Cyanobacterial and plant NDH-1 subunit O Arg_repressor PF01316.21 KIK62147.1 - 5.5 6.8 19.5 23 4.8 0.1 7.8 9 1 0 9 9 9 0 Arginine repressor, DNA binding domain F-box-like PF12937.7 KIK62148.1 - 0.00043 20.1 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like NACHT PF05729.12 KIK62150.1 - 0.015 15.2 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AhpC-TSA PF00578.21 KIK62150.1 - 0.017 15.0 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family DUF3187 PF11383.8 KIK62151.1 - 0.035 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) PHD PF00628.29 KIK62152.1 - 0.0011 18.8 10.0 0.0021 17.9 10.0 1.5 1 0 0 1 1 1 1 PHD-finger Shadoo PF14999.6 KIK62152.1 - 0.16 12.1 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DivIC PF04977.15 KIK62157.1 - 0.33 10.8 0.7 26 4.6 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Lzipper-MIP1 PF14389.6 KIK62157.1 - 0.81 10.0 3.6 1.7 9.0 1.0 2.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CxC4 PF18717.1 KIK62161.1 - 3e-46 156.5 0.0 4.8e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases TetR_C_23 PF17931.1 KIK62161.1 - 0.25 11.4 0.0 0.36 11.0 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain KDZ PF18758.1 KIK62162.1 - 0.00058 19.5 0.8 0.00068 19.3 0.8 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase T5orf172 PF10544.9 KIK62163.1 - 0.00076 20.0 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KIK62163.1 - 0.0012 19.5 0.0 0.0031 18.1 0.0 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Sugar_tr PF00083.24 KIK62166.1 - 5.2e-78 262.9 25.5 6e-78 262.7 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK62166.1 - 1.7e-30 106.1 57.9 8.4e-27 94.0 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Choline_kinase PF01633.20 KIK62167.1 - 0.058 13.0 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1996 PF09362.10 KIK62169.1 - 7.1e-44 150.5 0.1 7.8e-35 121.0 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) Ank_4 PF13637.6 KIK62171.1 - 1.5e-16 60.5 0.5 0.00023 21.7 0.3 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK62171.1 - 1.5e-14 54.4 1.4 5.3e-09 36.5 0.7 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK62171.1 - 1.1e-12 46.9 5.3 0.029 14.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KIK62171.1 - 7.5e-11 42.0 8.4 0.043 14.3 0.2 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK62171.1 - 4.3e-07 30.1 2.0 0.042 14.2 0.2 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) YajC PF02699.15 KIK62171.1 - 0.00037 20.3 0.7 12 5.9 0.0 3.9 2 1 2 4 4 4 2 Preprotein translocase subunit RTC4 PF14474.6 KIK62171.1 - 0.014 15.5 0.1 2.9 8.1 0.0 2.9 1 1 2 3 3 3 0 RTC4-like domain TbpB_B_D PF01298.18 KIK62171.1 - 0.025 15.0 3.8 1.4 9.3 1.3 2.8 2 1 1 3 3 3 0 C-lobe and N-lobe beta barrels of Tf-binding protein B PHB_acc PF05233.13 KIK62171.1 - 0.091 12.8 0.1 11 6.1 0.0 2.9 3 0 0 3 3 3 0 PHB accumulation regulatory domain RNA_GG_bind PF10258.9 KIK62171.1 - 0.48 10.5 2.8 12 6.0 0.1 3.3 1 1 3 4 4 4 0 PHAX RNA-binding domain DUF1843 PF08898.10 KIK62171.1 - 7.3 7.2 8.2 1.1e+02 3.5 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) DUF2686 PF10887.8 KIK62176.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Helitron_like_N PF14214.6 KIK62180.1 - 4.5e-10 40.1 0.1 4.4e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK62181.1 - 0.55 9.3 3.3 2.4 7.2 0.7 2.7 2 2 0 2 2 2 0 PIF1-like helicase zf-MYND PF01753.18 KIK62183.1 - 1.3e-08 34.8 9.1 2.3e-08 34.0 9.1 1.4 1 0 0 1 1 1 1 MYND finger RXT2_N PF08595.11 KIK62184.1 - 0.011 15.8 6.7 0.011 15.8 6.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Afi1 PF07792.12 KIK62184.1 - 2.5 8.6 19.6 2.3 8.7 11.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Vfa1 PF08432.10 KIK62184.1 - 4.3 7.6 22.0 1.4 9.3 11.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4820 PF16091.5 KIK62184.1 - 4.7 6.5 11.2 7.6 5.8 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) AP3D1 PF06375.11 KIK62187.1 - 0.038 14.2 4.7 0.043 14.1 4.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Dimer_Tnp_hAT PF05699.14 KIK62188.1 - 0.00038 20.2 0.0 0.00047 19.9 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ank_4 PF13637.6 KIK62189.1 - 2.4e-08 34.4 0.1 0.00073 20.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK62189.1 - 2.2e-07 31.4 3.8 8.3e-06 26.3 1.8 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK62189.1 - 0.0012 19.1 0.7 2.4 9.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KIK62189.1 - 0.0024 18.2 1.2 0.48 11.0 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.12 KIK62190.1 - 2.6e-11 43.7 0.0 4.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK62190.1 - 0.00024 21.5 0.0 0.00038 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KIK62190.1 - 0.0013 18.7 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK62190.1 - 0.0079 16.6 0.2 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 RNA helicase AhpC-TSA PF00578.21 KIK62190.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family NB-ARC PF00931.22 KIK62190.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KIK62190.1 - 0.03 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 KIK62190.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 KIK62190.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK62190.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein VIT PF08487.10 KIK62195.1 - 5.5e-26 91.0 0.2 3.3e-25 88.5 0.0 2.2 1 1 1 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK62195.1 - 1.2e-21 77.2 0.0 1.1e-20 74.1 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KIK62195.1 - 5.5e-12 46.3 0.0 1.4e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK62195.1 - 8.8e-10 39.2 0.0 2.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIK62195.1 - 2e-05 24.1 0.0 4.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Pkinase PF00069.25 KIK62197.1 - 3e-15 56.3 0.0 1.4e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62197.1 - 5.1e-08 32.5 0.0 9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK62197.1 - 0.01 14.6 4.8 0.037 12.8 4.8 1.9 1 1 0 1 1 1 0 Fungal protein kinase PIP49_C PF12260.8 KIK62197.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 SRP-alpha_N PF04086.13 KIK62197.1 - 5.3 6.9 13.9 7.9 6.3 13.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Proteasome PF00227.26 KIK62198.1 - 2e-56 190.5 0.1 2.5e-56 190.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK62198.1 - 6.9e-14 51.2 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Alpha-amylase PF00128.24 KIK62199.1 - 2.8e-18 66.6 1.9 7.3e-17 61.9 0.5 2.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KIK62199.1 - 2.7e-14 53.5 0.1 4.8e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIK62199.1 - 5.4e-07 29.3 0.0 9.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 AhpC-TSA PF00578.21 KIK62201.1 - 0.033 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family SMC_N PF02463.19 KIK62203.1 - 0.0012 18.3 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain 4HBT_2 PF13279.6 KIK62204.1 - 0.041 14.4 0.0 0.066 13.7 0.0 1.5 1 1 0 1 1 1 0 Thioesterase-like superfamily NYD-SP28 PF14772.6 KIK62205.1 - 0.025 14.6 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Sperm tail VIT PF08487.10 KIK62206.1 - 6.4e-25 87.5 1.3 6.6e-24 84.3 0.0 2.8 2 1 1 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK62206.1 - 5.8e-16 58.8 0.0 1e-13 51.5 0.0 3.3 2 1 0 2 2 2 1 von Willebrand factor type A domain Glyco_transf_5 PF08323.11 KIK62206.1 - 4.7e-11 42.9 0.0 8.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain VWA_2 PF13519.6 KIK62206.1 - 1.7e-06 28.6 0.0 8.3e-05 23.2 0.0 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KIK62206.1 - 8e-06 26.2 0.0 0.006 16.8 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Glycos_transf_1 PF00534.20 KIK62206.1 - 0.0016 18.0 0.0 1.3 8.5 0.0 3.0 4 0 0 4 4 4 2 Glycosyl transferases group 1 VWA_CoxE PF05762.14 KIK62206.1 - 0.016 14.6 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KIK62206.1 - 0.15 12.0 0.4 0.63 10.0 0.0 2.3 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain Sec23_trunk PF04811.15 KIK62206.1 - 0.19 11.3 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain NTP_transf_3 PF12804.7 KIK62208.1 - 0.075 13.4 0.0 0.075 13.4 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Ank_2 PF12796.7 KIK62212.1 - 4.6e-30 104.0 26.4 1.2e-10 41.8 2.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK62212.1 - 3.1e-23 81.8 3.8 9.7e-05 22.8 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK62212.1 - 3.4e-18 63.9 9.5 0.098 13.3 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KIK62212.1 - 1.8e-16 59.7 19.2 0.016 15.6 0.2 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KIK62212.1 - 3.3e-10 40.0 14.5 0.0017 18.6 0.2 5.3 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Mic1 PF07035.12 KIK62212.1 - 0.015 15.0 0.0 14 5.3 0.0 3.8 1 1 2 4 4 4 0 Colon cancer-associated protein Mic1-like DUF3710 PF12502.8 KIK62212.1 - 0.029 14.1 3.9 33 4.1 0.2 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3710) DUF3344 PF11824.8 KIK62212.1 - 0.056 13.0 3.4 11 5.6 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3344) Toprim_3 PF13362.6 KIK62212.1 - 0.16 12.3 7.3 7.3 7.0 0.1 3.1 2 1 1 3 3 3 0 Toprim domain PorB PF11565.8 KIK62212.1 - 1.5 9.3 8.6 93 3.5 0.4 4.2 1 1 3 4 4 4 0 Alpha helical Porin B Dimer_Tnp_hAT PF05699.14 KIK62213.1 - 2.8e-07 30.2 0.1 2.9e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_Rrp7 PF17799.1 KIK62214.1 - 0.022 14.6 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain AhpC-TSA PF00578.21 KIK62216.1 - 0.0012 18.7 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family NACHT PF05729.12 KIK62216.1 - 0.0082 16.1 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 NACHT domain zinc_ribbon_5 PF13719.6 KIK62216.1 - 0.17 11.7 0.6 0.43 10.4 0.1 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Ank_4 PF13637.6 KIK62217.1 - 2.9e-29 101.1 1.7 9.2e-06 26.1 0.1 8.5 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK62217.1 - 3.7e-27 94.7 9.5 4.9e-10 39.9 0.3 4.9 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK62217.1 - 6.7e-20 69.1 9.4 0.072 13.7 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KIK62217.1 - 3e-15 55.9 24.2 0.1 13.1 0.0 9.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KIK62217.1 - 6.1e-11 42.3 9.8 0.037 14.3 0.1 6.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) YajC PF02699.15 KIK62217.1 - 0.0085 16.0 11.1 38 4.3 0.0 6.8 2 2 5 7 7 7 0 Preprotein translocase subunit PHB_acc PF05233.13 KIK62217.1 - 0.042 13.9 2.0 1.2e+02 2.8 0.0 5.2 6 0 0 6 6 6 0 PHB accumulation regulatory domain RTC4 PF14474.6 KIK62217.1 - 0.37 11.0 11.8 13 6.0 0.0 5.6 1 1 7 8 8 8 0 RTC4-like domain PorB PF11565.8 KIK62217.1 - 4 7.9 11.3 46 4.5 0.0 5.0 2 2 2 5 5 5 0 Alpha helical Porin B WD40 PF00400.32 KIK62219.1 - 1.8e-122 395.7 42.0 7.6e-10 39.2 0.2 14.1 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62219.1 - 1.6e-57 191.8 14.8 0.0021 18.3 0.1 13.1 2 2 10 13 13 13 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62219.1 - 4.7e-25 86.9 17.0 0.73 9.9 0.0 14.1 15 0 0 15 15 14 5 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK62219.1 - 3.6e-17 62.9 0.1 0.00077 19.4 0.0 6.3 2 2 5 7 7 7 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK62219.1 - 5.3e-15 55.2 13.2 0.67 8.9 0.0 11.4 3 3 8 12 12 12 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK62219.1 - 9.2e-13 47.4 1.4 0.086 11.4 0.0 5.7 3 2 2 6 6 6 5 Cytochrome D1 heme domain Frtz PF11768.8 KIK62219.1 - 1.4e-10 40.2 0.0 4.1 5.6 0.0 8.8 5 3 5 10 10 10 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK62219.1 - 5.2e-10 39.3 21.0 0.0049 16.5 0.6 5.4 1 1 3 4 4 4 4 PQQ-like domain WD40_like PF17005.5 KIK62219.1 - 1.1e-09 38.1 0.0 1.3 8.3 0.0 7.0 5 2 2 7 7 7 2 WD40-like domain PQQ PF01011.21 KIK62219.1 - 2.2e-08 33.6 0.0 15 5.8 0.0 9.9 11 0 0 11 11 11 0 PQQ enzyme repeat FeThRed_A PF02941.15 KIK62219.1 - 3.8e-08 33.3 4.7 0.53 10.5 0.0 7.9 6 2 4 11 11 11 1 Ferredoxin thioredoxin reductase variable alpha chain PQQ_3 PF13570.6 KIK62219.1 - 2.5e-06 27.8 0.9 61 4.3 0.0 8.1 6 3 3 9 9 9 0 PQQ-like domain Nup160 PF11715.8 KIK62219.1 - 0.00017 20.4 5.4 12 4.3 0.0 7.3 2 2 6 10 10 10 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KIK62219.1 - 0.00022 20.8 17.1 5.4 6.8 0.1 10.6 14 0 0 14 14 13 1 Proteasome subunit A N-terminal signature Me-amine-dh_H PF06433.11 KIK62219.1 - 0.0003 19.8 0.1 0.48 9.2 0.1 4.7 3 2 0 5 5 5 1 Methylamine dehydrogenase heavy chain (MADH) CNH PF00780.22 KIK62219.1 - 0.00069 19.3 0.0 58 3.2 0.0 6.6 6 3 3 9 9 9 0 CNH domain 3-dmu-9_3-mt PF06983.13 KIK62219.1 - 0.003 18.1 1.3 8.6 6.9 0.0 6.2 6 3 4 10 10 7 0 3-demethylubiquinone-9 3-methyltransferase DUF5018 PF16410.5 KIK62219.1 - 0.015 14.0 0.1 3.5 6.2 0.0 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF5018) Fim-adh_lectin PF09222.10 KIK62219.1 - 0.028 13.9 2.5 12 5.4 0.0 5.0 5 2 0 5 5 5 0 Fimbrial adhesin F17-AG, lectin domain Utp8 PF10395.9 KIK62219.1 - 0.035 12.6 0.4 2.9 6.3 0.0 3.8 3 2 2 5 5 5 0 Utp8 family Peptidase_S9_N PF02897.15 KIK62219.1 - 0.045 12.5 9.8 11 4.6 0.0 6.3 5 4 3 8 8 8 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Rpn3_C PF08375.11 KIK62219.1 - 0.067 13.6 0.0 47 4.5 0.0 4.5 4 0 0 4 4 4 0 Proteasome regulatory subunit C-terminal DUF5114 PF17141.4 KIK62219.1 - 0.095 13.2 2.7 11 6.6 0.0 4.7 4 3 2 6 6 5 0 Domain of unknown function (DUF5114) zf-C2H2_6 PF13912.6 KIK62219.1 - 0.1 12.7 0.3 27 4.9 0.0 3.3 3 0 0 3 3 2 0 C2H2-type zinc finger DUF4469 PF14734.6 KIK62219.1 - 2.2 8.5 4.1 41 4.4 0.0 4.8 4 4 3 7 7 6 0 Domain of unknown function (DUF4469) with IG-like fold Helitron_like_N PF14214.6 KIK62224.1 - 1e-21 78.0 0.0 2.6e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK62224.1 - 3.6e-14 52.7 0.0 3.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 KIK62224.1 - 0.0039 16.9 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK62224.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MdcG PF10620.9 KIK62227.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG Acetyltransf_1 PF00583.25 KIK62228.1 - 3.8e-05 23.9 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK62228.1 - 0.00047 20.5 0.0 0.00069 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK62228.1 - 0.00072 19.6 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIK62228.1 - 0.0012 18.9 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK62228.1 - 0.0032 17.4 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK62228.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 KIK62228.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase DUF1772 PF08592.11 KIK62229.1 - 1.1e-30 106.7 2.3 1.4e-30 106.4 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SRTM1 PF15872.5 KIK62230.1 - 0.058 13.5 0.9 0.058 13.5 0.9 2.4 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 VIT PF08487.10 KIK62231.1 - 2e-05 24.7 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DUF4246 PF14033.6 KIK62232.1 - 1.9e-76 258.1 0.0 2.3e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Rotamase PF00639.21 KIK62233.1 - 3e-21 76.2 0.1 4.1e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KIK62233.1 - 1.7e-18 67.2 0.0 2.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KIK62233.1 - 1.7e-09 37.6 0.4 4.3e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KIK62233.1 - 0.00055 20.8 0.0 0.00077 20.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 KIK62233.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 WW domain MFS_1 PF07690.16 KIK62234.1 - 2.8e-15 56.1 48.2 1.8e-09 37.0 21.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK62234.1 - 0.044 12.6 26.7 0.043 12.7 9.9 3.4 2 2 0 2 2 2 0 Sugar (and other) transporter Acetyltransf_1 PF00583.25 KIK62235.1 - 1.4e-09 38.1 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIK62235.1 - 6.2e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK62235.1 - 6.9e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK62235.1 - 1.4e-05 25.4 0.0 3.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK62235.1 - 0.00048 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK62235.1 - 0.0022 18.1 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KIK62235.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK62235.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KIK62235.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase UCH PF00443.29 KIK62237.1 - 1.8e-54 184.9 0.0 2.7e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK62237.1 - 3.4e-27 95.9 7.9 2.8e-22 79.7 0.7 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Phage_r1t_holin PF16945.5 KIK62237.1 - 0.025 14.7 0.7 0.11 12.8 0.7 2.1 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Peptidase_C98 PF15499.6 KIK62237.1 - 0.061 12.8 3.2 0.1 12.0 1.4 2.1 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MOSC PF03473.17 KIK62238.1 - 4.7e-24 84.9 0.0 7.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KIK62238.1 - 2.9e-17 62.7 0.0 4.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain F-box PF00646.33 KIK62242.1 - 0.046 13.6 0.6 0.11 12.4 0.6 1.7 1 0 0 1 1 1 0 F-box domain DUF2263 PF10021.9 KIK62243.1 - 3.1e-17 63.3 0.0 4.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF2891 PF11199.8 KIK62243.1 - 0.24 10.3 0.0 0.4 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) WD40 PF00400.32 KIK62244.1 - 3.6e-78 255.5 47.3 2.5e-09 37.6 0.2 11.7 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62244.1 - 3.8e-27 94.4 0.1 0.0007 19.8 0.0 9.9 1 1 10 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK62244.1 - 2.5e-13 49.7 6.7 0.028 13.4 0.0 8.5 3 3 5 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK62244.1 - 8.3e-07 28.8 12.7 3.4 7.7 0.1 9.0 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK62244.1 - 1.3e-06 27.3 1.5 1.4 7.4 0.1 6.7 7 1 1 8 8 8 1 Nucleoporin Nup120/160 NACHT PF05729.12 KIK62244.1 - 2.1e-06 27.7 0.0 5.8e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Frtz PF11768.8 KIK62244.1 - 8.6e-06 24.3 0.0 0.041 12.2 0.0 4.1 4 1 1 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK62244.1 - 0.00023 21.6 0.0 0.001 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain PQQ PF01011.21 KIK62244.1 - 0.003 17.4 0.1 5.7 7.0 0.0 4.5 4 0 0 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 KIK62244.1 - 0.0033 16.8 0.8 1.1 8.6 0.0 4.0 4 1 0 4 4 4 1 WD40-like domain AAA_19 PF13245.6 KIK62244.1 - 0.0056 17.0 0.6 7.7 6.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain Nucleoporin_N PF08801.11 KIK62244.1 - 0.028 13.2 5.2 2 7.1 0.3 4.5 2 2 2 5 5 5 0 Nup133 N terminal like Nbas_N PF15492.6 KIK62244.1 - 0.064 12.6 8.2 3.9 6.7 0.0 5.7 5 3 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal UvrD-helicase PF00580.21 KIK62244.1 - 0.086 12.3 3.8 0.24 10.9 1.7 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 KIK62244.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 KIK62244.1 - 0.21 11.5 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC2_membrane PF01061.24 KIK62247.1 - 1.3e-70 237.1 51.2 4.3e-40 137.4 18.9 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIK62247.1 - 7.3e-33 114.0 0.0 6.8e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIK62247.1 - 1.5e-16 60.0 9.2 4.2e-13 49.0 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK62247.1 - 5.9e-11 42.8 0.7 1.8e-10 41.2 0.7 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 KIK62247.1 - 9.4e-06 26.2 0.0 0.0046 17.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK62247.1 - 0.0001 22.7 0.1 0.13 12.6 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK62247.1 - 0.00015 22.0 5.0 0.35 11.1 0.1 3.7 4 2 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KIK62247.1 - 0.00037 20.7 0.8 0.034 14.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KIK62247.1 - 0.0011 18.5 0.5 0.4 10.3 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KIK62247.1 - 0.0014 18.1 0.0 0.0095 15.4 0.0 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIK62247.1 - 0.0042 17.0 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KIK62247.1 - 0.0059 16.2 0.2 0.13 11.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIK62247.1 - 0.0072 16.2 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KIK62247.1 - 0.008 16.6 4.9 0.65 10.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 KIK62247.1 - 0.0095 16.2 2.2 0.38 11.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KIK62247.1 - 0.017 14.9 0.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain HDV_ag PF01517.18 KIK62247.1 - 0.055 13.3 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen AAA_19 PF13245.6 KIK62247.1 - 0.076 13.3 2.5 1.4 9.2 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK62247.1 - 0.34 10.6 7.5 2.4 7.8 0.0 3.5 4 1 0 4 4 4 0 AAA domain Colicin-DNase PF12639.7 KIK62247.1 - 2.5 9.0 5.7 29 5.6 1.7 2.6 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin EF-hand_6 PF13405.6 KIK62248.1 - 2.5e-05 23.9 0.1 0.094 12.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIK62248.1 - 0.00025 21.5 0.5 0.00025 21.5 0.5 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KIK62248.1 - 0.013 15.0 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.16 KIK62249.1 - 7e-11 41.7 31.7 7e-11 41.7 31.7 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily Phytoreo_Pns PF05451.11 KIK62249.1 - 0.008 15.4 0.2 0.019 14.1 0.1 1.6 2 0 0 2 2 2 1 Phytoreovirus nonstructural protein Pns10/11 Inositol_P PF00459.25 KIK62250.1 - 4.5e-67 226.4 0.0 5.2e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family ECH_1 PF00378.20 KIK62252.1 - 3.3e-36 124.9 0.0 3.9e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK62252.1 - 1e-13 51.5 0.0 4.4e-13 49.4 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Hydrophobin PF01185.18 KIK62253.1 - 2.9e-13 50.3 10.4 4.5e-13 49.6 10.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK62254.1 - 6.2e-14 52.4 11.6 9.7e-14 51.8 11.6 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK62255.1 - 5.7e-05 23.7 0.2 0.0001 22.9 0.2 1.4 1 0 0 1 1 1 1 Fungal hydrophobin Met_gamma_lyase PF06838.11 KIK62256.1 - 0.086 11.3 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Hydrophobin PF01185.18 KIK62257.1 - 2.8e-05 24.7 0.4 4.5e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK62258.1 - 2.4e-13 50.5 12.1 3.7e-13 49.9 12.1 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK62259.1 - 3.7e-13 49.9 12.4 5.7e-13 49.3 12.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK62260.1 - 0.00077 20.1 0.2 0.0019 18.8 0.2 1.7 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK62263.1 - 0.00021 21.8 0.4 0.00043 20.8 0.4 1.7 1 1 0 1 1 1 1 Fungal hydrophobin Transposase_23 PF03017.14 KIK62263.1 - 5.7 7.0 6.2 2 8.4 0.2 2.7 2 1 1 3 3 3 0 TNP1/EN/SPM transposase Hydrophobin PF01185.18 KIK62265.1 - 0.00024 21.7 0.2 0.00048 20.7 0.1 1.5 1 1 0 1 1 1 1 Fungal hydrophobin Transposase_23 PF03017.14 KIK62265.1 - 9 6.3 7.5 1.5 8.8 0.8 2.7 2 1 1 3 3 3 0 TNP1/EN/SPM transposase Hydrophobin PF01185.18 KIK62266.1 - 8.7e-12 45.5 5.5 8.9e-12 45.5 4.7 1.4 1 1 0 1 1 1 1 Fungal hydrophobin DUF726 PF05277.12 KIK62267.1 - 2.3e-109 365.4 2.0 3.7e-109 364.8 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 KIK62267.1 - 0.056 13.1 0.5 0.86 9.2 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold RAP1 PF07218.11 KIK62267.1 - 4.8 5.3 6.9 7.7 4.7 6.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.16 KIK62268.1 - 3.2e-21 75.6 47.0 4.2e-17 62.1 28.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CDP-OH_P_transf PF01066.21 KIK62271.1 - 8.2e-18 64.9 0.1 8.2e-18 64.9 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF218 PF02698.17 KIK62273.1 - 2.6e-12 46.9 0.0 5.7e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 DUF218 domain Exo70 PF03081.15 KIK62274.1 - 0.0064 15.6 2.3 0.019 14.0 0.1 2.0 1 1 0 2 2 2 1 Exo70 exocyst complex subunit EcoRI_methylase PF13651.6 KIK62274.1 - 0.057 12.6 0.3 0.096 11.9 0.3 1.3 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Suf PF05843.14 KIK62274.1 - 0.085 12.8 6.3 0.14 12.1 6.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Exonuc_VII_L PF02601.15 KIK62274.1 - 0.095 12.3 1.3 0.16 11.5 1.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pox_G5 PF04599.12 KIK62274.1 - 0.13 11.2 0.6 0.23 10.4 0.6 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein THOC7 PF05615.13 KIK62274.1 - 0.26 11.5 6.6 0.54 10.5 6.6 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 AhpC-TSA_2 PF13911.6 KIK62275.1 - 4.6e-20 71.8 0.0 6.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KIK62275.1 - 2e-07 30.8 0.0 2.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIK62275.1 - 7.6e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 KIK62275.1 - 0.0067 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF5562 PF17717.1 KIK62276.1 - 0.15 12.0 0.7 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5562) SelK_SelG PF10961.8 KIK62276.1 - 0.18 12.4 2.2 0.2 12.3 0.2 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Pam17 PF08566.10 KIK62276.1 - 0.59 10.0 2.1 4 7.3 0.4 2.4 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 Tmemb_170 PF10190.9 KIK62277.1 - 1.8 9.0 9.9 0.15 12.4 4.2 2.1 2 0 0 2 2 2 0 Putative transmembrane protein 170 PHO4 PF01384.20 KIK62277.1 - 2.3 7.2 11.2 6 5.8 11.1 1.6 1 1 0 1 1 1 0 Phosphate transporter family ABC_export PF16962.5 KIK62278.1 - 4.8 5.5 16.5 7.5 4.9 16.5 1.3 1 1 0 1 1 1 0 Putative ABC exporter EcoRI_methylase PF13651.6 KIK62279.1 - 0.096 11.9 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI THOC7 PF05615.13 KIK62279.1 - 0.27 11.5 6.4 0.52 10.6 5.6 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1151 PF06625.11 KIK62279.1 - 0.76 9.7 5.5 1.3 9.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) NPL4 PF05021.15 KIK62280.1 - 1.3e-89 300.6 0.0 1.5e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-RanBP PF00641.18 KIK62280.1 - 0.00027 20.2 1.3 0.0005 19.3 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 KIK62280.1 - 0.15 11.9 1.9 0.26 11.1 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain NmrA PF05368.13 KIK62281.1 - 4e-34 118.2 0.0 4.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK62281.1 - 4.1e-11 43.1 0.0 6.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK62281.1 - 1.6e-05 24.5 0.1 3.5e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK62281.1 - 0.00026 21.3 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KIK62281.1 - 0.026 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK62281.1 - 0.036 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KIK62282.1 - 2.5e-35 122.1 63.8 6.1e-27 94.5 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 KIK62282.1 - 0.024 14.8 0.1 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.22 KIK62283.1 - 3.3e-59 200.8 0.0 4.5e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KIK62284.1 - 6.5e-76 256.0 26.7 7.5e-76 255.8 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK62284.1 - 2.8e-29 102.1 57.1 2.4e-26 92.5 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIK62284.1 - 7.6e-06 24.7 1.6 7.6e-06 24.7 1.6 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein SPATA25 PF15218.6 KIK62285.1 - 0.019 14.7 0.7 0.033 14.0 0.1 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 25 PRIMA1 PF16101.5 KIK62285.1 - 0.092 12.8 0.0 0.092 12.8 0.0 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SKN1 PF03935.15 KIK62286.1 - 5e-184 612.4 4.3 5.8e-184 612.2 4.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PRIMA1 PF16101.5 KIK62287.1 - 0.0068 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 SPATA25 PF15218.6 KIK62287.1 - 0.017 14.9 0.5 0.054 13.2 0.1 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 25 MAGE_N PF12440.8 KIK62287.1 - 2.9 8.6 8.7 0.089 13.5 1.6 2.2 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal SKN1 PF03935.15 KIK62288.1 - 1.6e-187 623.9 5.4 1.9e-187 623.7 5.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aldo_ket_red PF00248.21 KIK62290.1 - 7.6e-68 228.9 0.0 1e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_23 PF13489.6 KIK62291.1 - 5.3e-11 42.6 0.0 9.1e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62291.1 - 3.7e-07 30.8 0.0 1.2e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK62291.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIK62291.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KIK62291.1 - 0.14 12.9 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 KIK62291.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.7 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Spherulin4 PF12138.8 KIK62292.1 - 4.2e-28 98.6 0.1 5.2e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glutaredoxin PF00462.24 KIK62294.1 - 1.3e-16 60.6 0.1 1.7e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 KIK62294.1 - 0.00019 21.4 0.1 0.00023 21.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK62294.1 - 0.00057 20.3 0.2 0.00078 19.9 0.2 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIK62294.1 - 0.0045 17.1 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_4 PF13462.6 KIK62294.1 - 0.01 16.0 1.0 1.3 9.2 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.6 KIK62294.1 - 0.038 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 KIK62294.1 - 0.049 14.1 0.0 0.062 13.7 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KIK62294.1 - 0.06 13.4 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.21 KIK62294.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DSBA PF01323.20 KIK62294.1 - 0.069 12.9 0.3 0.26 11.1 0.3 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Toxin-deaminase PF14424.6 KIK62294.1 - 0.076 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases LRR_4 PF12799.7 KIK62295.1 - 0.022 15.2 0.6 39 4.9 0.0 4.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.6 KIK62295.1 - 0.062 13.3 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KIK62295.1 - 0.12 12.3 0.6 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 KIK62296.1 - 0.04 14.4 3.2 0.5 10.9 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Methyltransf_2 PF00891.18 KIK62297.1 - 1.5e-24 86.4 0.0 3.8e-23 81.9 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KIK62297.1 - 0.00043 20.9 0.0 0.00089 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK62297.1 - 0.0022 17.8 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK62297.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KIK62297.1 - 0.027 15.1 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KIK62297.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KIK62298.1 - 8.1e-26 90.6 0.0 4.8e-23 81.6 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KIK62298.1 - 1.6e-05 24.7 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62298.1 - 0.00035 21.2 0.0 0.00074 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK62298.1 - 0.0091 15.6 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 KIK62298.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 KIK62298.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 KIK62298.1 - 0.15 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SnoaL PF07366.12 KIK62299.1 - 1e-25 90.0 0.0 1.1e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIK62299.1 - 6e-11 42.9 0.0 7.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Phage_CRI PF05144.14 KIK62299.1 - 0.16 11.3 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI Methyltransf_2 PF00891.18 KIK62301.1 - 1.7e-26 92.8 0.0 2e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KIK62301.1 - 3.9e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62301.1 - 0.00058 20.5 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK62301.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 KIK62301.1 - 0.12 11.7 0.1 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 KIK62301.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase SnoaL PF07366.12 KIK62302.1 - 7.2e-29 100.2 0.0 8e-29 100.0 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIK62302.1 - 5.5e-13 49.4 0.0 6.6e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4904 PF16247.5 KIK62302.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) CE2_N PF17996.1 KIK62303.1 - 2.4e-06 27.5 0.4 0.02 14.9 0.1 2.6 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal zf-NOSIP PF15906.5 KIK62308.1 - 0.00019 21.5 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Glyco_hydro_92 PF07971.12 KIK62310.1 - 7.4e-121 404.3 0.0 9.9e-121 403.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK62310.1 - 6.1e-39 134.3 0.1 9.2e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Methyltransf_2 PF00891.18 KIK62312.1 - 4.6e-20 71.8 0.0 2.9e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIK62312.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIK62312.1 - 0.0013 19.4 0.0 0.004 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIK62312.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KIK62312.1 - 0.02 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK62312.1 - 0.05 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF948 PF06103.11 KIK62313.1 - 0.0084 16.4 0.2 0.21 11.9 0.3 2.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) SesA PF17107.5 KIK62313.1 - 0.026 14.7 2.0 0.049 13.8 1.1 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases STN1_2 PF09170.10 KIK62313.1 - 0.087 13.0 0.9 0.14 12.3 0.9 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Taxilin PF09728.9 KIK62313.1 - 0.18 10.9 7.0 0.98 8.5 3.8 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein LOH1CR12 PF10158.9 KIK62313.1 - 0.22 11.6 2.2 0.38 10.8 1.2 1.8 1 1 0 2 2 2 0 Tumour suppressor protein Claudin_3 PF06653.11 KIK62314.1 - 0.037 14.0 5.0 0.052 13.5 5.0 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF1772 PF08592.11 KIK62314.1 - 0.087 13.1 0.2 0.099 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3446 PF11928.8 KIK62316.1 - 0.85 10.0 10.9 0.057 13.7 2.8 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain RT_RNaseH_2 PF17919.1 KIK62317.1 - 4.4e-09 36.3 0.0 5.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK62317.1 - 9.9e-09 35.4 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1772 PF08592.11 KIK62320.1 - 0.018 15.3 0.2 0.023 15.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) zf-RVT PF13966.6 KIK62321.1 - 5.6e-07 30.2 2.0 9.2e-07 29.5 1.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK62322.1 - 5.3e-06 26.1 0.0 8.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KIK62325.1 - 1.2e-127 412.0 42.8 1.3e-10 41.7 0.1 14.0 13 1 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62325.1 - 8.6e-38 128.5 17.1 0.0032 17.7 0.0 11.4 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK62325.1 - 1.1e-21 77.6 2.3 1.4e-05 25.1 0.1 5.8 2 1 4 7 7 7 6 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK62325.1 - 8.5e-17 61.4 8.4 0.51 9.6 0.1 10.7 9 2 2 11 11 11 4 WD40-like domain Nup160 PF11715.8 KIK62325.1 - 8.7e-13 47.8 18.7 1.4 7.5 0.0 11.1 5 3 7 12 12 12 4 Nucleoporin Nup120/160 PD40 PF07676.12 KIK62325.1 - 2.5e-09 36.8 0.0 6.4 6.8 0.0 7.8 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK62325.1 - 1.4e-07 31.6 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KIK62325.1 - 2e-07 30.3 5.4 9.5 5.1 0.0 8.7 4 3 5 10 10 10 0 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 KIK62325.1 - 9.2e-07 28.7 25.5 1.2 9.1 0.1 10.8 11 1 1 12 12 12 1 Nitrous oxide reductase propeller repeat AAA_16 PF13191.6 KIK62325.1 - 6e-06 26.7 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SecA_PP_bind PF01043.20 KIK62325.1 - 4.7e-05 24.0 7.1 63 4.3 0.0 8.3 11 1 0 12 12 9 0 SecA preprotein cross-linking domain COPI_C PF06957.11 KIK62325.1 - 0.00073 18.4 0.0 18 4.0 0.0 5.3 1 1 5 7 7 7 0 Coatomer (COPI) alpha subunit C-terminus Frtz PF11768.8 KIK62325.1 - 0.0024 16.3 0.0 34 2.6 0.0 4.9 2 1 2 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz DsbC_N PF10411.9 KIK62325.1 - 0.0034 16.8 9.9 69 3.0 0.0 8.5 10 0 0 10 10 10 0 Disulfide bond isomerase protein N-terminus ATPase_2 PF01637.18 KIK62325.1 - 0.0058 16.6 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK62325.1 - 0.0091 16.4 0.0 0.037 14.5 0.0 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK62325.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Imm17 PF15562.6 KIK62325.1 - 0.038 13.9 0.0 33 4.5 0.0 4.5 5 0 0 5 5 5 0 Immunity protein 17 NB-ARC PF00931.22 KIK62325.1 - 0.074 12.2 0.0 0.26 10.4 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain DUF2534 PF10749.9 KIK62326.1 - 0.095 12.9 0.3 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) ATP-synt_G PF04718.15 KIK62327.1 - 0.00058 20.6 0.0 0.0014 19.4 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit WD40 PF00400.32 KIK62329.1 - 1.6e-130 421.1 27.7 1.1e-11 45.0 0.1 12.4 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62329.1 - 4.9e-50 167.8 10.8 0.00032 20.9 0.1 12.2 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK62329.1 - 7.1e-20 71.7 0.9 0.00048 20.0 0.1 5.9 1 1 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK62329.1 - 9.5e-15 54.7 3.2 3.7 6.8 0.0 10.5 9 3 3 12 12 12 4 WD40-like domain Ge1_WD40 PF16529.5 KIK62329.1 - 3.2e-12 46.1 9.0 5.9 5.7 0.0 11.6 2 1 11 13 13 13 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK62329.1 - 3.2e-11 42.6 11.6 1.2 7.7 0.0 9.5 3 2 6 11 11 11 5 Nucleoporin Nup120/160 PD40 PF07676.12 KIK62329.1 - 2.7e-10 39.9 0.0 32 4.6 0.0 9.7 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK62329.1 - 2.2e-07 30.7 14.3 19 5.2 0.0 9.7 11 0 0 11 11 11 0 Nitrous oxide reductase propeller repeat Peptidase_S9_N PF02897.15 KIK62329.1 - 4.5e-06 25.7 2.6 2.4 6.8 0.0 6.4 2 2 6 8 8 8 2 Prolyl oligopeptidase, N-terminal beta-propeller domain NHL PF01436.21 KIK62329.1 - 0.00021 21.2 12.8 36 4.6 0.0 9.2 10 0 0 10 10 10 0 NHL repeat DsbC_N PF10411.9 KIK62329.1 - 0.0067 15.9 1.6 1.7e+02 1.7 0.0 6.2 6 0 0 6 6 6 0 Disulfide bond isomerase protein N-terminus Frtz PF11768.8 KIK62329.1 - 0.0075 14.6 0.0 41 2.3 0.0 5.2 4 3 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4596 PF15363.6 KIK62329.1 - 0.6 10.4 6.2 4 7.8 0.1 5.0 6 0 0 6 6 5 0 Domain of unknown function (DUF4596) Cuticle_4 PF15955.5 KIK62329.1 - 0.61 10.8 7.4 2e+02 2.8 0.0 6.1 8 0 0 8 8 7 0 Cuticle protein Phage_sheath_1 PF04984.14 KIK62329.1 - 3.2 7.6 7.0 1.2e+02 2.5 0.3 6.0 8 1 0 8 8 8 0 Phage tail sheath protein subtilisin-like domain Ceramidase_alk PF04734.13 KIK62331.1 - 7.5 5.1 5.7 7.8 5.0 5.7 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal ATP-synt_G PF04718.15 KIK62333.1 - 1.2e-12 48.5 1.2 2.4e-12 47.6 1.2 1.5 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit WD40 PF00400.32 KIK62334.1 - 1.7e-152 490.7 39.2 2.4e-10 40.8 0.3 15.3 14 1 1 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62334.1 - 1.3e-41 140.7 14.6 0.03 14.6 0.0 13.9 2 2 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK62334.1 - 9.5e-24 84.3 2.1 0.00036 20.5 0.1 6.6 1 1 4 7 7 7 6 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK62334.1 - 9.2e-18 64.3 3.7 1.9 7.3 0.0 12.4 4 2 9 14 14 14 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK62334.1 - 1.1e-17 64.3 1.3 0.089 12.1 0.0 11.1 10 3 1 11 11 11 4 WD40-like domain Nup160 PF11715.8 KIK62334.1 - 2.9e-15 55.9 19.3 0.25 10.0 0.1 11.7 6 5 5 12 12 12 7 Nucleoporin Nup120/160 PD40 PF07676.12 KIK62334.1 - 2.7e-12 46.3 0.0 36 4.5 0.0 11.9 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK62334.1 - 1.7e-05 24.6 14.6 26 4.8 0.0 10.5 12 1 0 13 13 13 0 Nitrous oxide reductase propeller repeat NHL PF01436.21 KIK62334.1 - 0.00013 21.8 24.1 13 6.0 0.1 11.8 14 0 0 14 14 13 0 NHL repeat DsbC_N PF10411.9 KIK62334.1 - 0.0022 17.4 15.1 2.4e+02 1.3 0.0 11.0 13 0 0 13 13 13 0 Disulfide bond isomerase protein N-terminus SdiA-regulated PF06977.11 KIK62334.1 - 0.0032 16.7 0.0 5.6 6.1 0.0 5.0 3 2 2 5 5 5 1 SdiA-regulated COPI_C PF06957.11 KIK62334.1 - 0.16 10.7 0.0 41 2.8 0.0 4.0 3 1 2 5 5 5 0 Coatomer (COPI) alpha subunit C-terminus Imm17 PF15562.6 KIK62334.1 - 0.18 11.7 0.0 1.2e+02 2.7 0.0 5.3 8 0 0 8 8 8 0 Immunity protein 17 DUF2574 PF10836.8 KIK62334.1 - 0.31 10.9 2.3 47 3.9 0.0 4.9 4 1 1 5 5 5 0 Protein of unknown function (DUF2574) LRR_10 PF18805.1 KIK62334.1 - 0.57 9.9 9.9 40 3.9 0.2 6.4 6 1 1 7 7 7 0 Leucine-rich repeat RTC4 PF14474.6 KIK62337.1 - 0.0054 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Transposase_mut PF00872.18 KIK62338.1 - 0.026 13.4 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Dopey_N PF04118.14 KIK62340.1 - 0.023 13.8 0.1 0.028 13.5 0.1 1.1 1 0 0 1 1 1 0 Dopey, N-terminal Arnt_C PF18583.1 KIK62340.1 - 0.035 13.7 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain FMN_red PF03358.15 KIK62340.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 NADPH-dependent FMN reductase RVT_3 PF13456.6 KIK62342.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase-like DUF1657 PF07870.11 KIK62346.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Pex19 PF04614.12 KIK62347.1 - 2.2e-59 201.2 14.7 2.2e-59 201.2 14.7 1.4 2 0 0 2 2 2 1 Pex19 protein family Adeno_terminal PF02459.15 KIK62347.1 - 0.049 12.0 0.4 0.07 11.5 0.4 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Pup PF05639.11 KIK62347.1 - 0.14 13.1 0.4 0.14 13.1 0.4 3.2 3 1 1 4 4 4 0 Pup-like protein CSN5_C PF18323.1 KIK62347.1 - 0.38 11.7 5.2 12 6.9 0.5 2.7 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Orthopox_F14 PF06076.12 KIK62347.1 - 0.61 10.4 3.3 11 6.3 0.2 2.6 2 1 0 2 2 2 0 Orthopoxvirus F14 protein YtxH PF12732.7 KIK62347.1 - 0.93 10.1 4.5 6.9 7.3 4.5 2.4 1 1 0 1 1 1 0 YtxH-like protein SLX9 PF15341.6 KIK62347.1 - 4.6 7.6 15.9 4.1 7.8 2.0 3.6 2 1 0 3 3 3 0 Ribosome biogenesis protein SLX9 O-FucT PF10250.9 KIK62348.1 - 7.3e-07 29.2 0.0 1.8e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase GDP_Man_Dehyd PF16363.5 KIK62349.1 - 2.3e-149 497.3 0.0 2.7e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK62349.1 - 2.4e-70 236.8 0.0 3.8e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK62349.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CENP-Q PF13094.6 KIK62350.1 - 0.032 14.5 0.7 0.032 14.5 0.7 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lzipper-MIP1 PF14389.6 KIK62350.1 - 0.057 13.7 1.9 3.3 8.1 0.3 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.11 KIK62350.1 - 0.47 9.3 4.6 0.055 12.4 0.3 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein SCP2 PF02036.17 KIK62351.1 - 1.4e-25 89.7 0.4 1.9e-25 89.3 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIK62351.1 - 1.6e-05 25.2 0.6 2.2e-05 24.8 0.6 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Cupredoxin_1 PF13473.6 KIK62351.1 - 0.019 15.1 0.1 0.097 12.8 0.1 1.9 1 1 0 1 1 1 0 Cupredoxin-like domain SCP_3 PF17844.1 KIK62351.1 - 0.052 13.3 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial SCP ortholog Ribosomal_L2_C PF03947.18 KIK62352.1 - 6.8e-48 162.0 0.7 1.2e-47 161.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIK62352.1 - 2.8e-23 81.7 0.2 5e-23 80.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain XPG_N PF00752.17 KIK62353.1 - 1.3e-34 118.7 0.0 2.5e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIK62353.1 - 3e-29 101.2 0.0 7.7e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KIK62353.1 - 2.9e-06 27.8 0.0 8e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Med8 PF10232.9 KIK62353.1 - 0.16 11.6 1.3 0.17 11.4 0.3 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Fe_dep_repr_C PF02742.15 KIK62353.1 - 0.35 11.0 2.2 3.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain Phosphodiest PF01663.22 KIK62354.1 - 6.8e-11 42.3 0.3 1.4e-10 41.3 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KIK62354.1 - 0.14 11.5 0.1 0.62 9.4 0.2 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily TatD_DNase PF01026.21 KIK62357.1 - 8e-42 143.4 0.0 9.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 KIK62357.1 - 0.016 15.0 0.2 0.64 9.7 0.0 3.1 1 1 1 2 2 2 0 Amidohydrolase ATR13 PF16829.5 KIK62357.1 - 0.047 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Ribosomal_S10 PF00338.22 KIK62358.1 - 5.7e-29 100.2 0.0 2.5e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e RF-1 PF00472.20 KIK62358.1 - 0.02 14.8 1.0 0.04 13.8 1.0 1.5 1 0 0 1 1 1 0 RF-1 domain Abhydrolase_1 PF00561.20 KIK62359.1 - 0.00032 20.4 0.0 0.14 11.8 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK62359.1 - 0.00061 19.3 0.0 0.0026 17.3 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.9 KIK62359.1 - 0.00077 18.2 0.0 0.0014 17.4 0.0 1.4 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.10 KIK62359.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.8 KIK62359.1 - 0.16 11.2 0.1 1.2 8.4 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PHD PF00628.29 KIK62360.1 - 3.8e-07 29.9 8.8 7.6e-07 28.9 8.8 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIK62360.1 - 0.006 16.8 1.5 0.02 15.1 1.5 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain ANAPC10 PF03256.16 KIK62361.1 - 1.9e-46 158.0 0.0 2.4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KIK62361.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain ThiF PF00899.21 KIK62362.1 - 7e-64 215.5 0.0 1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KIK62362.1 - 1.1e-11 45.2 0.0 2.6e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 KIK62362.1 - 0.072 13.2 0.0 0.23 11.5 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK62362.1 - 0.12 12.6 0.1 0.38 11.0 0.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UBX PF00789.20 KIK62363.1 - 1.4e-12 47.6 0.2 2.6e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 UBX domain PITH PF06201.13 KIK62364.1 - 1.4e-40 139.0 0.0 1.7e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain VID27 PF08553.10 KIK62364.1 - 0.06 12.4 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Glyco_hydro_18 PF00704.28 KIK62365.1 - 1.3e-23 84.2 0.3 4.2e-23 82.6 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DLH PF01738.18 KIK62366.1 - 4.6e-17 62.3 0.1 5.2e-17 62.1 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 KIK62367.1 - 1.9e-11 43.5 0.0 4.1e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK62367.1 - 3e-07 30.4 12.3 3e-07 30.4 12.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 KIK62368.1 - 3.6e-14 53.2 2.2 4.3e-14 52.9 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KIK62369.1 - 5.5e-14 52.6 0.1 6.6e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HYR PF02494.16 KIK62369.1 - 0.022 15.1 0.1 9.1 6.7 0.0 2.4 2 0 0 2 2 2 0 HYR domain CBM_5_12 PF02839.14 KIK62369.1 - 0.4 11.4 8.9 2.2 9.0 2.7 3.6 2 0 0 2 2 2 0 Carbohydrate binding domain Sporozoite_P67 PF05642.11 KIK62369.1 - 1.5 6.8 3.4 2 6.4 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Frag1 PF10277.9 KIK62372.1 - 5.8e-36 124.1 6.6 5.8e-36 124.1 6.6 2.5 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family cobW PF02492.19 KIK62373.1 - 2e-39 135.0 0.0 2.6e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIK62373.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 KIK62373.1 - 0.056 13.7 0.2 0.57 10.5 0.2 2.9 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 KIK62373.1 - 0.06 13.0 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KIK62373.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1574 PF07611.11 KIK62373.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1574) Pox_A32 PF04665.12 KIK62373.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 KIK62373.1 - 0.074 13.0 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KIK62373.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK62373.1 - 0.52 10.4 1.8 0.9 9.6 0.2 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SKG6 PF08693.10 KIK62374.1 - 0.0052 16.2 0.2 0.013 14.9 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Apc15p PF05841.11 KIK62374.1 - 7.1 7.5 8.2 2.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Apc15p protein DnaJ PF00226.31 KIK62376.1 - 5.5e-15 55.3 0.5 1.7e-14 53.7 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain eIF-1a PF01176.19 KIK62377.1 - 2e-23 81.9 0.1 2.9e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L37e PF01907.19 KIK62378.1 - 5.4e-26 90.5 13.9 8.8e-26 89.8 13.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KIK62378.1 - 0.0086 16.1 0.6 0.014 15.4 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 KIK62378.1 - 0.031 14.3 0.4 0.038 14.1 0.4 1.3 1 0 0 1 1 1 0 SelR domain HypA PF01155.19 KIK62378.1 - 0.039 14.0 0.3 0.055 13.5 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KIK62378.1 - 0.52 9.8 3.5 5.1 6.6 3.5 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 KIK62378.1 - 2.1 7.9 4.8 4.4 6.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon Esterase_phd PF10503.9 KIK62379.1 - 1.8e-06 27.6 0.0 5.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.12 KIK62379.1 - 0.00029 19.6 0.0 0.053 12.2 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KIK62379.1 - 0.00063 19.3 0.2 0.023 14.1 0.1 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIK62379.1 - 0.015 15.1 0.2 0.083 12.7 0.2 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KIK62379.1 - 0.071 12.7 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KIK62379.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Complex1_LYR PF05347.15 KIK62380.1 - 1.1e-09 38.1 1.6 1.5e-08 34.6 0.2 2.5 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIK62380.1 - 0.0023 18.6 0.6 0.0036 18.0 0.6 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Sugar_tr PF00083.24 KIK62381.1 - 9.3e-52 176.4 23.5 1.1e-51 176.1 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK62381.1 - 2.3e-19 69.6 30.9 2.3e-19 69.6 30.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 KIK62383.1 - 4.9e-19 69.2 0.0 7.8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK62383.1 - 2.1e-15 57.1 0.0 1.7e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF572 PF04502.13 KIK62384.1 - 7e-69 233.0 0.3 8.2e-69 232.7 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) ARID PF01388.21 KIK62385.1 - 4.5e-12 46.5 0.1 2.7e-11 44.0 0.0 2.5 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 KIK62385.1 - 0.00087 19.5 0.0 0.00087 19.5 0.0 4.3 6 0 0 6 6 6 1 Mediator complex subunit 15 SNARE_assoc PF09335.11 KIK62387.1 - 7.5e-11 42.6 5.8 2e-10 41.2 5.8 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein SAD_SRA PF02182.17 KIK62389.1 - 6e-13 48.8 0.0 6.4e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 SAD/SRA domain SAD_SRA PF02182.17 KIK62390.1 - 8.6e-15 54.8 0.2 9.3e-15 54.7 0.2 1.0 1 0 0 1 1 1 1 SAD/SRA domain Peptidase_S10 PF00450.22 KIK62391.1 - 1.6e-60 205.7 0.0 2.1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Epimerase PF01370.21 KIK62392.1 - 4.8e-20 72.0 0.0 6.7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK62392.1 - 5.6e-17 62.1 0.0 7.7e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK62392.1 - 1.1e-10 41.8 0.0 3.5e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK62392.1 - 2.7e-10 39.7 0.0 3.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIK62392.1 - 9.5e-06 24.9 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIK62392.1 - 5.3e-05 22.5 0.1 0.00011 21.5 0.1 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK62392.1 - 7.9e-05 22.3 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK62392.1 - 9.2e-05 22.0 0.1 0.00014 21.4 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KIK62392.1 - 0.092 11.9 0.0 0.66 9.1 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein adh_short_C2 PF13561.6 KIK62392.1 - 0.16 11.5 0.1 0.4 10.2 0.1 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.20 KIK62392.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TT_ORF2 PF02957.15 KIK62394.1 - 0.56 11.1 4.2 2 9.4 4.2 1.9 1 0 0 1 1 1 0 TT viral ORF2 p450 PF00067.22 KIK62396.1 - 2.3e-58 198.1 0.3 2.6e-57 194.6 0.3 2.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2597 PF10772.9 KIK62397.1 - 0.18 11.9 0.0 0.58 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) Ribosomal_L10 PF00466.20 KIK62398.1 - 1.1e-24 86.4 0.5 1.2e-23 83.1 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KIK62398.1 - 9e-23 80.1 0.1 1.7e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KIK62398.1 - 2.2e-21 76.2 8.7 2.2e-21 76.2 8.7 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Glyco_transf_20 PF00982.21 KIK62399.1 - 1.5e-185 617.4 0.0 6.9e-139 463.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KIK62399.1 - 0.00031 21.2 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIK62399.1 - 0.026 14.0 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Cation_ATPase_C PF00689.21 KIK62401.1 - 4.1e-47 160.2 9.2 4.1e-47 160.2 9.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIK62401.1 - 1.9e-35 122.1 0.1 1.9e-35 122.1 0.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIK62401.1 - 1.7e-18 66.5 0.0 3.3e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK62401.1 - 4.1e-14 53.4 0.2 1.6e-13 51.5 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK62401.1 - 1.1e-08 34.6 0.3 7.8e-08 31.9 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK62401.1 - 0.00032 20.5 0.3 0.019 14.7 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Insulin_TMD PF17870.1 KIK62401.1 - 1.6 8.9 4.0 15 5.8 1.6 2.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment RPN7 PF10602.9 KIK62402.1 - 1.6e-47 161.4 0.1 3e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIK62402.1 - 9.2e-16 58.3 0.1 9.9e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KIK62402.1 - 0.0036 17.3 1.0 0.72 10.1 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Sigma70_r4 PF04545.16 KIK62402.1 - 0.067 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_14 PF13428.6 KIK62402.1 - 0.15 13.0 3.6 17 6.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5633 PF18656.1 KIK62402.1 - 0.49 10.3 0.1 0.49 10.3 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5633) DUF2370 PF10176.9 KIK62403.1 - 3.1e-66 223.2 0.0 5.1e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) UPF0061 PF02696.14 KIK62404.1 - 5.2e-100 335.4 0.0 1.2e-99 334.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Pirin PF02678.16 KIK62405.1 - 1e-29 102.7 0.2 1.9e-29 101.8 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KIK62405.1 - 1.9e-25 89.2 0.0 7.1e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KIK62405.1 - 0.01 15.5 0.3 0.04 13.6 0.3 2.0 2 0 0 2 2 2 0 Cupin domain p450 PF00067.22 KIK62406.1 - 2e-63 214.8 0.0 2.6e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC PF07967.13 KIK62407.1 - 8.5e-28 97.0 0.0 2.1e-25 89.3 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KIK62407.1 - 2.5e-13 50.0 1.0 1e-07 32.0 0.0 3.5 3 1 0 3 3 3 2 Rsm1-like DM PF00751.18 KIK62407.1 - 0.0084 16.0 0.7 1.4 8.8 0.1 2.6 2 0 0 2 2 2 2 DM DNA binding domain Actin PF00022.19 KIK62408.1 - 2e-87 293.4 0.0 1e-85 287.8 0.0 2.0 1 1 0 1 1 1 1 Actin DUF1778 PF08681.11 KIK62408.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) GATA PF00320.27 KIK62409.1 - 4.9e-09 35.7 3.6 8.5e-09 34.9 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-C4H2 PF10146.9 KIK62409.1 - 1.5 9.1 4.6 2.6 8.3 4.6 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein G_path_suppress PF15991.5 KIK62409.1 - 6.1 6.9 7.6 11 6.0 7.5 1.6 1 1 0 1 1 1 0 G-protein pathway suppressor APG17 PF04108.12 KIK62410.1 - 5.5e-78 262.8 13.5 6.4e-78 262.6 13.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4763 PF15960.5 KIK62410.1 - 0.00068 19.0 4.6 0.00068 19.0 4.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) RasGAP_C PF03836.15 KIK62410.1 - 0.018 15.1 4.7 0.51 10.5 0.0 2.8 2 1 0 2 2 2 0 RasGAP C-terminus DUF3106 PF11304.8 KIK62410.1 - 0.043 14.3 8.0 0.67 10.4 0.1 3.7 5 0 0 5 5 4 0 Protein of unknown function (DUF3106) RNA_pol_Rpc34 PF05158.12 KIK62410.1 - 0.095 12.1 0.1 0.095 12.1 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit Med29 PF11568.8 KIK62410.1 - 0.22 11.7 2.9 0.59 10.4 1.0 2.5 2 1 0 2 2 2 0 Mediator complex subunit 29 Sec8_exocyst PF04048.14 KIK62410.1 - 0.47 10.3 8.7 1 9.3 3.0 3.3 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain V-SNARE_C PF12352.8 KIK62410.1 - 0.58 10.5 4.4 12 6.3 0.6 3.5 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus BLOC1_2 PF10046.9 KIK62410.1 - 0.81 10.0 7.4 2.4 8.5 2.0 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KIK62410.1 - 0.87 9.7 13.1 1.1 9.4 6.0 2.5 2 0 0 2 2 2 0 Tropomyosin like LMBR1 PF04791.16 KIK62410.1 - 0.88 8.4 6.0 1.4 7.7 0.8 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein NPV_P10 PF05531.12 KIK62410.1 - 0.93 10.0 6.3 6.3 7.3 0.6 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein GCN5L1 PF06320.13 KIK62410.1 - 1 9.6 6.8 4.4 7.5 1.5 2.9 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF3450 PF11932.8 KIK62410.1 - 1.7 7.9 18.8 0.62 9.3 0.9 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) FUSC PF04632.12 KIK62410.1 - 1.9 6.9 9.5 0.88 8.0 5.9 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 KIK62410.1 - 2.3 9.0 8.5 33 5.3 0.0 3.8 3 1 1 4 4 3 0 Occludin homology domain Spc7 PF08317.11 KIK62410.1 - 4.7 6.0 17.0 0.17 10.7 7.2 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein Sec34 PF04136.15 KIK62410.1 - 5.8 6.8 12.0 11 5.9 1.3 3.7 3 1 1 4 4 4 0 Sec34-like family Phage_GP20 PF06810.11 KIK62410.1 - 7 6.4 9.5 6.2 6.6 1.9 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 ZapB PF06005.12 KIK62410.1 - 7.5 7.1 19.7 0.26 11.7 3.3 3.6 3 0 0 3 3 3 0 Cell division protein ZapB LysM PF01476.20 KIK62411.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 LysM domain zf-RING_5 PF14634.6 KIK62411.1 - 2.4 8.2 9.3 4.1 7.4 9.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PRK PF00485.18 KIK62412.1 - 0.0029 17.4 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KIK62412.1 - 0.0037 17.7 0.0 0.0048 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KIK62412.1 - 0.0084 15.1 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KIK62412.1 - 0.0091 16.5 0.1 0.073 13.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK62412.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK62412.1 - 0.023 14.9 0.0 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KIK62412.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 KIK62412.1 - 0.091 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-C2H2 PF00096.26 KIK62415.1 - 8.6e-09 35.4 6.3 0.00022 21.5 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK62415.1 - 2.2e-06 27.8 0.3 2.2e-06 27.8 0.3 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK62415.1 - 9.6e-05 22.9 7.4 0.042 14.7 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK62415.1 - 0.00059 19.5 2.1 0.09 12.5 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KIK62415.1 - 0.0014 18.3 0.1 0.0014 18.3 0.1 2.0 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KIK62415.1 - 0.0051 16.7 1.7 0.0051 16.7 1.7 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 KIK62415.1 - 0.089 13.2 0.5 14 6.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF4653 PF15546.6 KIK62415.1 - 0.091 12.4 1.3 0.13 11.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) zf-C2H2_jaz PF12171.8 KIK62415.1 - 0.19 12.1 0.1 22 5.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EthD PF07110.11 KIK62416.1 - 1.4e-05 26.1 0.2 0.16 13.1 0.0 2.5 2 1 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KIK62416.1 - 0.08 13.4 0.0 4.4 7.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4286) RAP1 PF07218.11 KIK62417.1 - 1.6 6.9 4.0 2.2 6.4 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRM_1 PF00076.22 KIK62418.1 - 6.8e-09 35.4 0.2 0.0024 17.6 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EthD PF07110.11 KIK62419.1 - 2.2e-05 25.5 0.3 0.27 12.4 0.0 2.8 2 1 0 2 2 2 2 EthD domain EIF_2_alpha PF07541.12 KIK62420.1 - 2.1e-36 124.5 0.0 3.5e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KIK62420.1 - 2.1e-12 47.2 1.0 3.9e-12 46.3 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DUF2944 PF11161.8 KIK62420.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DPBB_1 PF03330.18 KIK62421.1 - 3.7e-06 27.1 0.5 9.9e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KIK62421.1 - 3.6e-05 23.6 0.2 7.4e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Barwin family DUF3695 PF12494.8 KIK62421.1 - 0.038 13.9 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) zf-HC3 PF16827.5 KIK62421.1 - 0.063 13.5 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 zinc-finger Pol_alpha_B_N PF08418.10 KIK62421.1 - 0.13 12.2 2.4 0.15 12.0 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MSA-2c PF12238.8 KIK62421.1 - 0.2 11.6 6.4 0.3 11.0 6.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c SPX PF03105.19 KIK62421.1 - 0.9 9.4 4.8 1.1 9.1 4.8 1.1 1 0 0 1 1 1 0 SPX domain Hamartin PF04388.12 KIK62421.1 - 2.7 6.6 6.3 3 6.4 6.3 1.1 1 0 0 1 1 1 0 Hamartin protein Isochorismatase PF00857.20 KIK62422.1 - 2.4e-33 115.8 0.0 2.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Get5_C PF18514.1 KIK62422.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Get5 C-terminal domain RA PF00788.23 KIK62423.1 - 0.087 13.5 0.0 0.44 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Glyco_transf_28 PF03033.20 KIK62425.1 - 1.6e-17 63.8 0.0 4.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIK62425.1 - 1.5e-06 27.3 0.0 2.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK62425.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF5327 PF17261.2 KIK62426.1 - 0.086 13.6 0.2 0.16 12.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5327) BTB PF00651.31 KIK62427.1 - 6.6e-12 45.7 0.0 8.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Nup_retrotrp_bd PF10599.9 KIK62427.1 - 9.5 7.0 9.3 0.3 11.8 1.9 2.3 3 0 0 3 3 3 0 Retro-transposon transporting motif Cpn60_TCP1 PF00118.24 KIK62428.1 - 1.2e-84 284.7 3.2 2.2e-84 283.9 3.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family p450 PF00067.22 KIK62429.1 - 8.7e-70 235.7 0.0 1.9e-69 234.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF1894 PF08979.11 KIK62429.1 - 0.024 15.0 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) Metallophos PF00149.28 KIK62431.1 - 1.1e-12 48.9 0.3 6.3e-12 46.4 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KIK62431.1 - 0.037 12.3 0.3 0.14 10.4 0.0 2.0 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase Ank_2 PF12796.7 KIK62432.1 - 1.2e-23 83.5 0.5 4.6e-10 39.9 0.0 4.7 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK62432.1 - 2.7e-19 69.3 6.5 1.4e-05 25.5 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK62432.1 - 8e-17 61.1 4.4 3.3e-06 27.3 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK62432.1 - 4e-14 51.3 4.2 4.4e-05 23.6 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KIK62432.1 - 3.1e-13 49.5 7.7 0.00014 22.1 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Phage_Coat_B PF05356.11 KIK62432.1 - 0.094 12.6 0.4 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Phage Coat protein B TAP_C PF03943.13 KIK62433.1 - 3.4e-15 55.4 0.4 1.4e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 TAP C-terminal domain NTF2 PF02136.20 KIK62433.1 - 3.8e-06 27.5 0.0 2.6e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KIK62433.1 - 0.38 10.5 7.5 1 9.1 5.3 2.7 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KIK62433.1 - 1.9 9.1 10.0 0.79 10.2 3.2 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Vps39_1 PF10366.9 KIK62434.1 - 2.4e-28 98.6 0.5 3.2e-26 91.7 0.0 3.6 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KIK62434.1 - 3.7e-22 78.8 0.1 8e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KIK62434.1 - 2.7e-17 63.0 4.1 1.9e-13 50.5 1.5 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS CNH PF00780.22 KIK62434.1 - 2.1e-10 40.7 0.0 9.8e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 CNH domain TPR_19 PF14559.6 KIK62434.1 - 0.00016 22.1 3.0 0.0018 18.7 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat WD40_like PF17005.5 KIK62434.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain TPR_4 PF07721.14 KIK62434.1 - 0.072 13.8 1.4 4 8.4 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK62434.1 - 0.11 13.4 5.5 66 4.7 0.0 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK62434.1 - 0.29 11.4 3.7 8.7 6.7 0.0 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KIK62434.1 - 0.36 11.5 2.3 4.9 7.9 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK62434.1 - 0.43 10.5 11.8 1.1 9.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK62434.1 - 0.68 10.3 14.1 8.8 6.7 0.0 5.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK62434.1 - 8 6.8 14.2 11 6.5 0.2 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Glyco_hydro_3_C PF01915.22 KIK62435.1 - 1.8e-48 165.2 0.1 4.9e-48 163.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK62435.1 - 1.3e-26 93.8 0.0 7.8e-26 91.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK62435.1 - 1.5e-20 73.1 0.0 2.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Senescence PF06911.12 KIK62436.1 - 2.6e-46 158.2 3.8 3.6e-46 157.8 3.8 1.2 1 0 0 1 1 1 1 Senescence-associated protein Corona_S2 PF01601.16 KIK62437.1 - 0.034 12.6 0.3 0.04 12.4 0.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Colicin_im PF03857.13 KIK62437.1 - 0.054 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Colicin immunity protein DUF1295 PF06966.12 KIK62438.1 - 3.3e-44 151.2 0.1 4.1e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK62438.1 - 0.00026 21.4 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KIK62438.1 - 0.0031 16.4 0.0 0.0054 15.5 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KIK62438.1 - 0.011 16.1 0.1 0.041 14.3 0.0 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Steroid_dh PF02544.16 KIK62438.1 - 0.027 14.4 0.5 0.074 13.0 0.2 1.8 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase TLP-20 PF06088.11 KIK62439.1 - 0.003 17.5 0.1 0.08 12.8 0.0 2.1 2 0 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Myb_DNA-binding PF00249.31 KIK62439.1 - 0.0068 16.6 0.3 0.011 16.0 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sugar_tr PF00083.24 KIK62441.1 - 8.5e-38 130.4 34.2 1.6e-20 73.4 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK62441.1 - 3.1e-19 69.1 40.3 5.8e-15 55.1 13.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIK62442.1 - 0.0015 18.4 0.2 0.0056 16.6 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK62442.1 - 0.038 14.0 0.3 0.29 11.1 0.0 2.5 3 0 0 3 3 3 0 F-box-like domain Sugar_tr PF00083.24 KIK62445.1 - 7.9e-33 114.0 28.5 3.6e-19 69.0 6.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK62445.1 - 9.3e-21 74.1 37.9 3e-14 52.7 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK62446.1 - 2.5e-34 118.9 30.7 2.3e-20 72.9 9.6 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK62446.1 - 2e-18 66.4 42.6 9.3e-13 47.8 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK62448.1 - 2.4e-35 122.3 28.4 1.1e-21 77.3 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK62448.1 - 2.7e-17 62.8 43.8 7.6e-15 54.7 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KIK62448.1 - 0.53 10.1 3.2 46 3.9 0.0 3.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Sld5 PF05916.11 KIK62449.1 - 3.9e-06 27.3 0.0 5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein His_Phos_2 PF00328.22 KIK62450.1 - 0.17 11.2 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) MafB19-deam PF14437.6 KIK62451.1 - 3.2e-22 78.7 0.0 4.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KIK62451.1 - 5.7e-22 77.5 0.0 8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KIK62451.1 - 0.00079 19.5 0.2 0.01 15.9 0.2 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KIK62451.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 KIK62451.1 - 0.0033 17.4 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 KIK62451.1 - 0.0045 17.1 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KIK62451.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.4 2 0 0 2 2 2 1 APOBEC3 APOBEC2 PF18772.1 KIK62451.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC1 PF18769.1 KIK62451.1 - 0.024 14.9 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 APOBEC_N PF08210.11 KIK62451.1 - 0.053 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF3830 PF12903.7 KIK62451.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3830) Inv-AAD PF18785.1 KIK62451.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase SIR2 PF02146.17 KIK62452.1 - 3e-31 108.7 0.0 8e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 Sir2 family BCDHK_Adom3 PF10436.9 KIK62453.1 - 1.5e-65 220.0 0.0 5.1e-65 218.2 0.0 1.9 2 1 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIK62453.1 - 5e-12 46.3 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK62453.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRM_3 PF08777.11 KIK62454.1 - 4e-10 39.7 0.0 0.0033 17.5 0.0 3.7 2 2 0 2 2 2 2 RNA binding motif Ribosomal_L4 PF00573.22 KIK62454.1 - 0.0012 18.6 0.4 0.24 11.0 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L4/L1 family RRM_1 PF00076.22 KIK62454.1 - 0.0026 17.5 0.9 2.2 8.2 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arb1 PF09692.10 KIK62456.1 - 0.21 10.7 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 UDPGT PF00201.18 KIK62457.1 - 2.5e-15 56.3 0.1 7.7e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK62457.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain p450 PF00067.22 KIK62458.1 - 2.9e-60 204.3 0.0 3.6e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Carn_acyltransf PF00755.20 KIK62459.1 - 3e-161 538.0 0.0 3.4e-161 537.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CBP_BcsO PF17037.5 KIK62459.1 - 0.007 16.6 0.2 0.012 15.8 0.2 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsO Glyco_transf_90 PF05686.12 KIK62460.1 - 1.4e-18 67.0 0.1 6.1e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 90 SNF2_N PF00176.23 KIK62461.1 - 3.1e-52 177.4 0.1 1.1e-51 175.7 0.0 1.8 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK62461.1 - 3.7e-18 65.9 0.0 6.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK62461.1 - 0.012 15.4 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase SOG2 PF10428.9 KIK62461.1 - 0.7 9.0 13.9 1.1 8.4 13.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 KIK62462.1 - 0.0012 18.7 0.2 0.0071 16.2 0.0 2.5 2 1 0 2 2 2 1 F-box-like LisH_TPL PF17814.1 KIK62462.1 - 0.04 13.6 0.7 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 LisH-like dimerisation domain F-box PF00646.33 KIK62462.1 - 0.072 13.0 0.0 0.072 13.0 0.0 2.6 3 0 0 3 3 3 0 F-box domain F-box PF00646.33 KIK62463.1 - 8.3e-05 22.4 0.1 0.0003 20.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK62463.1 - 0.00018 21.3 0.1 0.00065 19.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LisH_TPL PF17814.1 KIK62463.1 - 0.21 11.3 0.7 24 4.7 0.0 2.7 2 0 0 2 2 2 0 LisH-like dimerisation domain AAA PF00004.29 KIK62464.1 - 1.9e-10 41.2 0.0 4.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK62464.1 - 9.1e-10 38.9 0.1 2.2e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK62464.1 - 4.2e-09 37.0 0.0 2.9e-07 31.0 0.0 2.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK62464.1 - 4.3e-05 23.5 0.1 0.00011 22.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 KIK62464.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_14 PF13173.6 KIK62464.1 - 0.0017 18.4 0.0 0.0051 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK62464.1 - 0.0027 18.1 0.1 0.014 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK62464.1 - 0.0044 17.4 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 KIK62464.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.8 2 1 0 2 2 1 1 ATPase domain predominantly from Archaea ResIII PF04851.15 KIK62464.1 - 0.0056 16.7 0.0 0.0093 16.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 KIK62464.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KIK62464.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 KIK62464.1 - 0.016 14.1 0.0 0.38 9.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KIK62464.1 - 0.035 13.4 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KIK62464.1 - 0.047 13.2 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 KIK62464.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_5 PF07728.14 KIK62464.1 - 0.057 13.4 0.1 0.47 10.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KIK62464.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KIK62464.1 - 0.094 12.1 0.0 1.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Barstar PF01337.18 KIK62464.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Barstar (barnase inhibitor) AAA_35 PF14516.6 KIK62464.1 - 0.11 11.3 0.0 0.57 9.0 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.15 KIK62464.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase ABC_membrane PF00664.23 KIK62471.1 - 2.6e-69 233.9 25.4 8.3e-38 130.6 13.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK62471.1 - 4.1e-52 176.3 0.0 9.6e-31 107.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK62471.1 - 2.7e-08 33.5 3.8 0.0037 16.7 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK62471.1 - 2.1e-05 25.0 0.9 0.16 12.4 0.1 3.8 3 1 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 KIK62471.1 - 3.1e-05 24.0 1.3 0.02 14.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KIK62471.1 - 5.1e-05 22.6 1.3 0.0047 16.2 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KIK62471.1 - 0.0001 22.3 0.8 0.38 10.6 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KIK62471.1 - 0.00012 22.0 0.8 0.11 12.3 0.1 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK62471.1 - 0.00015 21.4 1.6 0.12 12.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK62471.1 - 0.0019 18.5 4.5 2.7 8.3 0.7 3.7 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIK62471.1 - 0.0084 16.6 5.5 0.63 10.5 0.2 3.2 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KIK62471.1 - 0.014 15.4 0.6 0.65 10.0 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KIK62471.1 - 0.014 15.2 4.1 13 5.5 0.4 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KIK62471.1 - 0.015 15.2 1.8 0.33 10.9 0.4 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KIK62471.1 - 0.016 14.9 0.2 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KIK62471.1 - 0.018 15.1 0.3 2.4 8.1 0.0 3.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Roc PF08477.13 KIK62471.1 - 0.019 15.2 1.6 5.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KIK62471.1 - 0.025 14.1 1.1 3 7.3 0.2 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KIK62471.1 - 0.032 14.1 0.9 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 KIK62471.1 - 0.039 12.9 1.1 2.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KIK62471.1 - 0.088 12.9 4.0 0.25 11.4 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 KIK62471.1 - 0.1 12.2 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIK62471.1 - 0.1 12.3 1.6 2.3 7.8 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain cobW PF02492.19 KIK62471.1 - 0.11 12.1 2.2 0.94 9.0 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 KIK62471.1 - 0.11 12.1 0.2 19 4.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 KIK62471.1 - 0.17 11.6 5.7 6.9 6.3 0.4 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KIK62471.1 - 0.17 11.1 3.1 3.5 6.7 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KIK62471.1 - 0.23 11.4 1.0 9 6.2 0.0 2.6 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 KIK62471.1 - 0.24 11.4 6.7 1.8 8.6 0.3 2.8 3 0 0 3 3 2 0 Dynamin family PduV-EutP PF10662.9 KIK62471.1 - 0.24 11.1 0.9 5.2 6.8 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.9 KIK62471.1 - 0.91 8.4 3.4 2.1 7.1 0.4 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 KIK62471.1 - 1.1 9.4 3.0 49 4.1 0.4 3.4 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 KIK62472.1 - 5.5e-26 91.5 0.0 7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62472.1 - 2.8e-12 46.5 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK62472.1 - 1.1e-08 34.2 0.0 1.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK62472.1 - 3.8e-05 23.7 0.0 0.049 13.5 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family WD40 PF00400.32 KIK62473.1 - 9.8e-19 67.4 9.8 0.00024 21.8 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62473.1 - 5.2e-06 26.7 0.0 0.00021 21.5 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 KIK62473.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat eIF2A PF08662.11 KIK62473.1 - 0.024 14.5 0.0 0.84 9.5 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK62473.1 - 0.03 12.7 0.0 0.67 8.2 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz F-box-like PF12937.7 KIK62474.1 - 1e-08 34.9 2.8 2.6e-08 33.6 2.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK62474.1 - 0.0019 18.0 2.1 0.011 15.5 2.1 2.4 1 1 0 1 1 1 1 F-box domain DSBA PF01323.20 KIK62475.1 - 4.1e-23 82.2 0.0 4.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KIK62475.1 - 0.0077 16.3 0.5 0.039 14.0 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin domain Thioredoxin_5 PF13743.6 KIK62475.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Pkinase PF00069.25 KIK62480.1 - 3.9e-60 203.4 0.0 5.3e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62480.1 - 2.9e-31 108.7 0.0 1.1e-30 106.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK62480.1 - 5.4e-05 22.1 0.0 8.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK62480.1 - 0.00042 19.7 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK62480.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 KIK62481.1 - 2.1e-18 66.3 8.4 0.003 18.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62481.1 - 2.6e-10 40.5 0.0 0.0033 17.7 0.0 4.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK62481.1 - 0.00025 20.5 0.0 0.0041 16.5 0.0 2.4 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 KIK62481.1 - 0.037 12.3 0.0 2.4 6.4 0.0 2.4 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK62481.1 - 0.055 12.1 0.0 0.13 10.8 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 6PF2K PF01591.18 KIK62483.1 - 3e-68 229.4 0.0 4.3e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIK62483.1 - 2.4e-36 125.2 0.0 4.8e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIK62483.1 - 0.00012 22.3 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Methyltransf_32 PF13679.6 KIK62483.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain KTI12 PF08433.10 KIK62483.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF2110 PF09883.9 KIK62483.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) GBP PF02263.19 KIK62483.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Frag1 PF10277.9 KIK62484.1 - 1.9e-41 142.0 15.7 2.2e-41 141.8 15.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1461 PF07314.11 KIK62484.1 - 0.016 15.1 9.5 0.76 9.7 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) DUF3754 PF12576.8 KIK62484.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3754) DUF5453 PF17534.2 KIK62484.1 - 1.5 8.7 11.6 0.029 14.3 2.8 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5453) DUF202 PF02656.15 KIK62484.1 - 2.7 8.5 18.6 0.31 11.5 0.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF202) EI24 PF07264.11 KIK62484.1 - 3 8.1 22.0 11 6.2 22.0 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) C2 PF00168.30 KIK62485.1 - 1.3e-13 51.2 0.1 2.5e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 C2 domain CCDC50_N PF15295.6 KIK62485.1 - 3.3 7.9 20.6 3 8.0 0.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus DEAD PF00270.29 KIK62486.1 - 3.5e-38 131.1 0.0 8.2e-38 129.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK62486.1 - 9.4e-23 80.7 0.1 7.7e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK62486.1 - 1.2e-09 38.4 0.0 3e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KIK62486.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 KIK62486.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK62486.1 - 0.11 12.7 2.4 3 8.1 0.0 3.1 4 0 0 4 4 4 0 AAA domain Flavi_DEAD PF07652.14 KIK62486.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 KIK62486.1 - 0.88 8.9 6.5 0.9 8.8 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit COesterase PF00135.28 KIK62488.1 - 9.4e-82 275.5 0.4 1.4e-77 261.8 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK62488.1 - 1.1e-07 31.9 0.4 6.3e-07 29.5 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold GBP_C PF02841.14 KIK62490.1 - 6.5 6.1 23.8 2.2 7.6 19.5 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 KIK62491.1 - 9.1e-13 48.3 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK62491.1 - 0.00063 19.8 0.1 0.1 12.7 0.2 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KIK62491.1 - 0.0018 18.2 0.0 0.0084 16.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KIK62491.1 - 0.0035 16.7 0.0 0.0066 15.8 0.0 1.4 1 1 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KIK62491.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B COesterase PF00135.28 KIK62492.1 - 5.3e-82 276.3 0.6 2.1e-78 264.5 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK62492.1 - 5.4e-08 33.0 0.4 3.1e-07 30.5 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK62492.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-HIT PF04438.16 KIK62493.1 - 4.5e-09 36.0 9.3 8.2e-09 35.2 9.3 1.4 1 0 0 1 1 1 1 HIT zinc finger Arylsulfotran_2 PF14269.6 KIK62494.1 - 2.5e-55 188.0 2.1 3.9e-55 187.4 2.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK62494.1 - 7.6e-10 38.2 0.4 7.6e-09 34.9 0.4 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 KIK62495.1 - 1.3e-53 182.3 2.1 1.7e-53 181.9 2.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK62495.1 - 4.2e-12 45.7 0.2 4.8e-11 42.2 0.2 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 KIK62497.1 - 1.5e-52 178.9 0.5 2e-52 178.4 0.5 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK62497.1 - 4.9e-11 42.2 1.8 6.2e-09 35.2 0.3 3.9 3 1 0 4 4 4 1 Arylsulfotransferase (ASST) MaAIMP_sms PF16951.5 KIK62497.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Putative methionine and alanine importer, small subunit Arylsulfotran_2 PF14269.6 KIK62498.1 - 3e-50 171.3 0.0 6.6e-50 170.2 0.0 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK62498.1 - 1.2e-13 50.7 0.2 6.1e-12 45.1 0.0 3.1 4 1 0 4 4 4 1 Arylsulfotransferase (ASST) SRP_TPR_like PF17004.5 KIK62501.1 - 1.5e-13 50.8 3.0 2.4e-13 50.1 3.0 1.4 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_19 PF14559.6 KIK62501.1 - 5e-08 33.3 3.6 0.19 12.3 0.0 3.5 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK62501.1 - 1.5e-07 30.9 5.5 0.044 13.9 1.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK62501.1 - 3.9e-07 30.2 4.6 0.016 15.4 3.5 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIK62501.1 - 5.8e-05 23.6 1.1 2.5 9.1 0.0 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK62501.1 - 8.2e-05 23.0 1.2 0.24 12.1 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat SRP72 PF08492.12 KIK62501.1 - 0.00012 22.4 0.2 0.00012 22.4 0.2 2.0 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_15 PF13429.6 KIK62501.1 - 0.00027 20.3 3.6 0.11 11.7 2.1 2.1 1 1 0 2 2 2 2 Tetratricopeptide repeat DUF2225 PF09986.9 KIK62501.1 - 0.00074 19.3 1.0 0.0011 18.7 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_1 PF00515.28 KIK62501.1 - 0.0013 18.5 5.6 1.5 8.8 1.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIK62501.1 - 0.0018 18.8 0.2 3 8.3 0.0 2.4 2 1 0 2 2 2 2 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KIK62501.1 - 0.003 17.6 0.1 4.5 7.4 0.0 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KIK62501.1 - 0.0059 16.9 4.7 0.02 15.2 3.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK62501.1 - 0.0093 16.3 2.5 0.13 12.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK62501.1 - 0.013 15.4 2.1 0.51 10.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK62501.1 - 0.013 14.8 3.0 0.089 12.1 2.9 1.9 1 1 1 2 2 2 0 MalT-like TPR region TPR_9 PF13371.6 KIK62501.1 - 0.016 15.3 0.1 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK62501.1 - 0.042 14.5 1.7 6.2 7.6 0.6 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat DUF4011 PF13195.6 KIK62501.1 - 0.06 13.3 0.2 0.093 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF627 PF04781.12 KIK62501.1 - 0.069 13.2 0.0 0.59 10.2 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF627) TPR_8 PF13181.6 KIK62501.1 - 0.17 12.2 1.5 1.4e+02 3.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK62501.1 - 0.45 10.6 10.9 0.055 13.5 3.8 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.20 KIK62502.1 - 4.1e-129 430.4 0.0 6.2e-129 429.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KIK62502.1 - 2.3e-14 53.4 0.5 2.3e-14 53.4 0.5 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK62502.1 - 2.5e-06 27.8 0.2 7.9e-05 23.0 0.0 2.6 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KIK62502.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 KIK62502.1 - 0.002 16.8 0.0 0.0056 15.3 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KIK62502.1 - 0.0076 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Terpene_synth_C PF03936.16 KIK62503.1 - 0.00031 20.2 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.19 KIK62504.1 - 5.8e-32 109.4 0.2 1.9e-31 107.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KIK62504.1 - 4.8e-28 97.6 0.1 8.1e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KIK62504.1 - 0.0029 17.6 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease SurA_N_2 PF13623.6 KIK62504.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain WD40 PF00400.32 KIK62505.1 - 3.4e-18 65.7 1.9 0.00095 19.9 0.0 5.6 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62505.1 - 4.9e-10 39.6 0.0 0.11 12.8 0.0 4.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK62505.1 - 0.47 10.5 4.2 59 3.8 0.1 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MitoNEET_N PF10660.9 KIK62506.1 - 0.01 15.9 0.2 0.02 14.9 0.2 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus RAP1 PF07218.11 KIK62507.1 - 0.039 12.2 6.8 0.094 11.0 6.6 1.8 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF5044 PF16447.5 KIK62507.1 - 0.065 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) MOZ_SAS PF01853.18 KIK62508.1 - 2.1e-67 226.3 0.1 3e-67 225.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIK62508.1 - 2e-20 72.1 2.2 2.4e-20 71.9 0.3 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KIK62508.1 - 0.066 13.3 0.8 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.6 KIK62510.1 - 0.00022 21.5 0.6 0.00033 21.0 0.6 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Ras PF00071.22 KIK62511.1 - 2.1e-58 196.5 0.1 2.5e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK62511.1 - 2.8e-20 72.7 0.0 5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK62511.1 - 1.6e-08 34.2 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK62511.1 - 3.1e-05 24.0 0.0 0.05 13.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIK62511.1 - 3.5e-05 23.4 0.1 6.7e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK62511.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK62511.1 - 0.0055 16.2 0.1 0.014 14.9 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 KIK62511.1 - 0.056 12.6 0.4 1.5 7.9 0.3 2.0 1 1 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KIK62511.1 - 0.088 12.6 2.1 0.56 9.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ser_hydrolase PF06821.13 KIK62511.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase BLOC1_2 PF10046.9 KIK62513.1 - 0.067 13.5 1.5 24 5.3 0.0 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HNHc_6 PF16784.5 KIK62513.1 - 0.09 12.3 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Putative HNHc nuclease TMF_DNA_bd PF12329.8 KIK62513.1 - 1.8 8.6 5.5 1.5 8.9 1.0 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CIA30 PF08547.12 KIK62514.1 - 1.5e-23 83.6 0.0 2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KIK62514.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain Git3 PF11710.8 KIK62516.1 - 1.7 8.4 10.8 3.4 7.4 10.8 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 IMS PF00817.20 KIK62517.1 - 3.1e-41 140.8 0.0 1.6e-40 138.5 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KIK62517.1 - 1.2e-12 48.6 0.0 2.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KIK62517.1 - 1.7e-05 24.3 5.1 0.0058 16.2 0.9 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KIK62517.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif zf-H2C2_2 PF13465.6 KIK62517.1 - 0.035 14.6 0.6 0.084 13.3 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 KIK62517.1 - 0.045 13.7 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain CpXC PF14353.6 KIK62517.1 - 0.17 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 CpXC protein Pyr_redox_2 PF07992.14 KIK62519.1 - 5.1e-53 180.2 2.0 6.6e-53 179.9 2.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KIK62519.1 - 2.4e-18 65.8 0.1 5.8e-18 64.6 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 KIK62519.1 - 3.3e-11 43.0 0.2 6e-10 38.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK62519.1 - 5.2e-10 39.7 6.2 2.1e-08 34.6 0.7 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KIK62519.1 - 2.3e-07 31.2 0.0 7.8e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KIK62519.1 - 8.5e-07 28.9 0.0 3.1e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KIK62519.1 - 0.0059 15.8 0.1 1.7 7.7 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KIK62519.1 - 0.011 16.1 0.5 0.61 10.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KIK62519.1 - 0.036 12.8 0.3 1.8 7.1 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK62519.1 - 0.049 13.6 0.4 12 5.8 0.0 3.1 2 1 0 3 3 3 0 FAD-NAD(P)-binding Mannosyl_trans3 PF11051.8 KIK62519.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Pkinase PF00069.25 KIK62520.1 - 1.7e-48 165.3 0.0 2.4e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62520.1 - 5.3e-19 68.5 0.0 8.9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIK62520.1 - 0.052 13.1 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 KIK62520.1 - 0.11 12.4 0.2 0.34 10.8 0.2 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIK62520.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ThuA PF06283.11 KIK62521.1 - 1.2e-59 202.1 0.1 1.4e-59 201.9 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation LytTR PF04397.15 KIK62522.1 - 0.15 12.3 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 LytTr DNA-binding domain DUF5051 PF16473.5 KIK62523.1 - 0.066 13.2 0.1 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like Asp PF00026.23 KIK62524.1 - 4.8e-68 229.9 2.3 5.7e-68 229.6 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK62524.1 - 6.2e-11 42.8 0.8 4.8e-09 36.7 1.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal ECH_1 PF00378.20 KIK62525.1 - 1.7e-25 89.8 0.0 2.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK62525.1 - 8.8e-10 38.6 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase B12-binding_2 PF02607.17 KIK62525.1 - 0.043 14.2 0.2 16 6.0 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain Peptidase_S49 PF01343.18 KIK62525.1 - 0.061 13.3 0.1 14 5.6 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 Pkinase PF00069.25 KIK62527.1 - 1.8e-22 80.0 0.1 6.7e-10 38.8 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62527.1 - 0.0097 15.2 0.1 0.13 11.5 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase TF_AP-2 PF03299.14 KIK62528.1 - 0.2 11.6 0.8 0.42 10.6 0.1 1.8 2 0 0 2 2 2 0 Transcription factor AP-2 Response_reg PF00072.24 KIK62531.1 - 9.5e-17 61.2 0.0 2.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KIK62531.1 - 1.3e-16 61.1 0.6 6.1e-16 58.9 0.2 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIK62531.1 - 1.3e-13 50.7 0.2 4.2e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KIK62531.1 - 4.1e-11 43.7 0.1 5.5e-06 27.0 0.0 2.9 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KIK62531.1 - 0.0016 18.8 0.0 0.63 10.4 0.0 2.8 2 0 0 2 2 2 2 GAF domain zf-RING_6 PF14835.6 KIK62532.1 - 0.0065 16.3 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF3990 PF13151.6 KIK62533.1 - 1.2e-05 25.0 0.0 2.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3990) PARP PF00644.20 KIK62533.1 - 0.074 12.6 0.6 0.26 10.9 0.3 2.0 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Hamartin PF04388.12 KIK62533.1 - 2.7 6.6 13.3 3.1 6.3 13.3 1.2 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 KIK62533.1 - 4.3 5.9 12.0 5.5 5.5 12.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-box-like PF12937.7 KIK62536.1 - 9.6e-05 22.2 0.1 0.00027 20.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like HMGL-like PF00682.19 KIK62537.1 - 5.4e-81 272.0 0.4 8e-81 271.5 0.4 1.3 1 0 0 1 1 1 1 HMGL-like UDG PF03167.19 KIK62539.1 - 6.8e-21 74.9 0.1 3.3e-20 72.7 0.1 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.21 KIK62540.1 - 0.00028 20.9 7.1 0.00045 20.2 7.1 1.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK62540.1 - 0.00032 20.7 2.1 0.00032 20.7 2.1 1.5 2 0 0 2 2 2 1 Basic region leucine zipper HAP1_N PF04849.13 KIK62540.1 - 0.018 14.2 0.3 0.02 14.1 0.3 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TSC22 PF01166.18 KIK62540.1 - 0.019 15.3 0.2 0.027 14.8 0.2 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KIK62540.1 - 0.021 14.7 0.6 0.034 14.0 0.6 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BMFP PF04380.13 KIK62540.1 - 0.15 12.6 3.1 0.23 12.0 3.1 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity Methyltr_RsmB-F PF01189.17 KIK62541.1 - 4.3e-26 91.8 0.0 8.7e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F ABC_transp_aux PF09822.9 KIK62541.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Fibrillarin PF01269.17 KIK62541.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DnaJ_C PF01556.18 KIK62542.1 - 1.4e-37 129.1 0.0 2e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK62542.1 - 8.9e-21 73.8 0.5 1.7e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK62542.1 - 3.1e-12 46.7 22.2 5.1e-12 46.0 22.2 1.4 1 0 0 1 1 1 1 DnaJ central domain RPT PF13446.6 KIK62542.1 - 0.022 14.6 0.0 0.094 12.7 0.0 2.0 1 1 1 2 2 2 0 A repeated domain in UCH-protein GP38 PF05268.11 KIK62542.1 - 1.5 8.4 9.6 2.8 7.5 8.4 2.0 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 Anti-TRAP PF15777.5 KIK62542.1 - 1.7 8.7 18.8 0.94 9.5 4.3 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KIK62542.1 - 3.3 7.8 13.7 5.7 7.0 1.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Astro_capsid_p PF12226.8 KIK62542.1 - 7.2 5.7 7.7 3.4 6.7 5.5 1.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein RAG2_PHD PF13341.6 KIK62543.1 - 0.043 13.9 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 RAG2 PHD domain Transport_MerF PF11431.8 KIK62543.1 - 0.1 12.5 2.8 0.11 12.4 1.1 1.7 1 1 1 2 2 2 0 Membrane transport protein MerF GMC_oxred_N PF00732.19 KIK62544.1 - 5.5e-66 223.0 0.0 7.5e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK62544.1 - 7.1e-35 120.6 0.0 1.2e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK62544.1 - 0.0029 16.7 0.1 0.0043 16.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK62544.1 - 0.0042 16.7 0.4 0.012 15.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK62544.1 - 0.0044 17.2 0.1 0.016 15.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK62544.1 - 0.041 13.1 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIK62544.1 - 0.058 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KIK62544.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KIK62544.1 - 0.097 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK62544.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK62544.1 - 0.21 10.3 0.1 0.3 9.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KIK62544.1 - 0.59 8.9 2.3 0.25 10.1 0.2 1.4 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 KIK62545.1 - 2.5e-09 37.0 0.1 2.8e-09 36.8 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK62545.1 - 0.00078 18.6 0.1 0.00089 18.4 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK62545.1 - 0.0019 18.4 0.1 0.0026 17.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK62545.1 - 0.003 16.8 0.0 0.0033 16.7 0.0 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK62545.1 - 0.0058 16.3 0.4 0.0065 16.1 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK62545.1 - 0.015 14.2 0.2 0.017 14.0 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK62545.1 - 0.016 14.5 0.2 0.017 14.3 0.2 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK62545.1 - 0.018 14.2 0.2 0.019 14.0 0.2 1.0 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIK62545.1 - 0.041 12.6 0.1 0.044 12.5 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KIK62545.1 - 0.056 13.7 0.1 0.07 13.4 0.1 1.1 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KIK62545.1 - 0.12 11.6 0.2 0.14 11.4 0.2 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_C PF05199.13 KIK62546.1 - 5e-39 134.1 0.0 7.4e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK62546.1 - 6.1e-27 94.8 0.0 8.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Paf67 PF10255.9 KIK62547.1 - 2e-134 448.6 0.0 3.5e-133 444.5 0.0 2.0 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KIK62547.1 - 0.019 15.0 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1129 PF06570.11 KIK62548.1 - 0.00088 18.8 1.4 0.00088 18.8 1.4 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1129) DUF1295 PF06966.12 KIK62550.1 - 8.9e-28 97.4 10.1 1.2e-23 83.8 3.0 3.5 3 1 0 3 3 3 3 Protein of unknown function (DUF1295) GMC_oxred_C PF05199.13 KIK62551.1 - 7.9e-37 127.0 0.0 1.2e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK62551.1 - 6.6e-35 120.9 0.0 9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK62552.1 - 2.5e-09 36.9 0.1 2.8e-09 36.8 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK62552.1 - 0.0007 18.7 0.1 0.00081 18.5 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK62552.1 - 0.0017 18.5 0.1 0.0024 18.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK62552.1 - 0.0024 17.1 0.1 0.0028 17.0 0.1 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK62552.1 - 0.0041 16.7 0.3 0.0047 16.6 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK62552.1 - 0.0093 15.2 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK62552.1 - 0.015 14.4 0.2 0.016 14.3 0.2 1.0 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIK62552.1 - 0.02 13.8 0.2 0.022 13.6 0.2 1.0 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KIK62552.1 - 0.037 12.7 0.1 0.04 12.6 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KIK62552.1 - 0.049 13.9 0.1 0.064 13.5 0.1 1.1 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KIK62552.1 - 0.11 11.7 0.2 0.12 11.6 0.2 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ANKH PF07260.11 KIK62552.1 - 0.12 11.5 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) GMC_oxred_N PF00732.19 KIK62553.1 - 3.4e-41 141.5 0.0 4.7e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK62553.1 - 2e-39 135.4 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK62554.1 - 1.1e-65 222.0 0.0 1.4e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK62554.1 - 4.2e-37 127.8 0.0 6.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK62554.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK62554.1 - 0.0085 15.2 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK62554.1 - 0.038 13.1 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KIK62554.1 - 0.044 13.4 0.1 0.091 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK62554.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KIK62554.1 - 0.094 11.9 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KIK62555.1 - 9.3e-52 176.2 0.0 4.8e-50 170.6 0.0 2.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK62555.1 - 9.8e-37 126.7 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK62557.1 - 8.7e-39 133.3 0.0 1.2e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK62557.1 - 8.2e-26 91.1 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK62558.1 - 6.3e-63 212.9 0.0 8e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK62558.1 - 1.3e-37 129.6 0.0 1.8e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK62558.1 - 0.00026 21.2 0.0 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK62558.1 - 0.0028 16.9 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KIK62558.1 - 0.0081 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK62558.1 - 0.0095 15.5 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK62558.1 - 0.024 13.9 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK62558.1 - 0.076 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIK62558.1 - 0.2 10.5 0.1 0.34 9.7 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Methyltransf_11 PF08241.12 KIK62559.1 - 1.6e-11 44.7 0.0 3.4e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62559.1 - 9.6e-10 39.0 0.0 3.2e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK62559.1 - 3.8e-06 26.8 0.0 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK62559.1 - 1.1e-05 26.1 0.0 3.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIK62559.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_28 PF02636.17 KIK62559.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 KIK62559.1 - 0.11 13.5 0.0 0.27 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPGT PF00201.18 KIK62564.1 - 7.8e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NACHT PF05729.12 KIK62566.1 - 0.0049 16.8 0.1 0.025 14.5 0.1 2.0 1 1 1 2 2 2 1 NACHT domain NACHT PF05729.12 KIK62567.1 - 0.0001 22.3 0.1 0.00015 21.7 0.1 1.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK62567.1 - 0.0002 21.8 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK62567.1 - 0.0015 18.9 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KIK62567.1 - 0.0099 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK62567.1 - 0.059 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KIK62567.1 - 0.067 12.3 0.2 0.084 11.9 0.2 1.3 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KIK62567.1 - 0.079 12.7 0.4 0.2 11.3 0.3 1.7 1 1 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 KIK62567.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KIK62567.1 - 0.1 12.2 1.8 0.39 10.3 0.1 2.0 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK62567.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIK62567.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK62567.1 - 0.17 11.8 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ALG3 PF05208.13 KIK62568.1 - 0.18 11.2 0.1 0.23 10.8 0.1 1.1 1 0 0 1 1 1 0 ALG3 protein PGI PF00342.19 KIK62568.1 - 0.23 10.0 0.0 0.87 8.1 0.0 1.7 1 1 1 2 2 2 0 Phosphoglucose isomerase Pro-kuma_activ PF09286.11 KIK62569.1 - 1.6e-26 93.3 0.3 4.2e-22 79.0 0.1 3.2 2 1 1 3 3 3 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK62569.1 - 1.1e-06 28.2 1.6 2.1e-06 27.2 0.6 1.8 2 0 0 2 2 2 1 Subtilase family Peptidase_M16_C PF05193.21 KIK62569.1 - 0.018 15.0 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF5609 PF18429.1 KIK62569.1 - 0.19 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) NCA2 PF08637.10 KIK62570.1 - 6.5e-74 248.7 0.0 6.3e-71 238.9 0.0 3.1 2 1 0 2 2 2 2 ATP synthase regulation protein NCA2 HCV_NS5a_C PF12941.7 KIK62570.1 - 0.065 13.1 2.7 0.095 12.5 2.7 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Gti1_Pac2 PF09729.9 KIK62572.1 - 1.5e-37 129.5 0.1 2e-37 129.0 0.1 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KIK62573.1 - 4.4e-34 118.2 4.0 7.9e-26 91.3 0.2 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family WD40 PF00400.32 KIK62574.1 - 5.8e-26 90.2 14.3 3.6e-06 27.6 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62574.1 - 9.9e-11 41.8 0.0 0.024 14.9 0.0 5.4 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1442 PF07279.11 KIK62574.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) PQQ_2 PF13360.6 KIK62574.1 - 0.044 13.4 3.1 0.57 9.7 1.1 2.8 2 1 1 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 KIK62574.1 - 0.047 12.7 0.0 9.6 5.1 0.0 2.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK62574.1 - 0.15 12.1 2.3 15 5.7 0.1 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK62574.1 - 1.4 9.5 14.7 9.1 6.9 0.0 4.9 3 2 2 5 5 5 0 PQQ-like domain Pectinesterase PF01095.19 KIK62575.1 - 1.8e-43 148.4 5.6 2.3e-43 148.0 5.6 1.0 1 0 0 1 1 1 1 Pectinesterase PI3K_1B_p101 PF10486.9 KIK62576.1 - 0.46 8.2 5.4 0.67 7.7 5.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Abhydrolase_3 PF07859.13 KIK62577.1 - 1.6e-13 51.0 0.0 2.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK62577.1 - 6.7e-12 45.0 2.0 3.6e-11 42.6 2.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KIK62577.1 - 9.6e-07 28.0 0.0 1.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK62577.1 - 3.3e-06 26.3 0.0 4.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 KIK62577.1 - 4e-05 24.3 0.6 9.5e-05 23.1 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 KIK62577.1 - 0.0028 16.2 0.1 0.024 13.2 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 KIK62577.1 - 0.003 17.3 0.1 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIK62577.1 - 0.065 12.5 2.2 1.1 8.5 1.8 2.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIK62577.1 - 0.14 11.6 0.2 0.69 9.3 0.0 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Methyltransf_25 PF13649.6 KIK62578.1 - 2.3e-05 25.0 0.0 0.00094 19.8 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK62578.1 - 0.11 13.2 0.0 0.64 10.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62579.1 - 5.6e-05 23.8 0.0 0.025 15.3 0.0 2.3 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KIK62579.1 - 0.14 12.9 0.0 1.7 9.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62580.1 - 0.00028 21.5 0.0 0.024 15.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KIK62581.1 - 3.3e-12 46.9 0.0 5.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62581.1 - 3.3e-11 43.7 0.0 5.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK62581.1 - 2.2e-06 28.3 0.0 3.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK62581.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KIK62581.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CCDC32 PF14989.6 KIK62581.1 - 0.057 13.4 0.1 0.12 12.3 0.1 1.5 2 0 0 2 2 2 0 Coiled-coil domain containing 32 Methyltransf_16 PF10294.9 KIK62581.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 KIK62581.1 - 0.11 12.3 0.0 0.81 9.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 KIK62581.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_3 PF01494.19 KIK62582.1 - 3.4e-09 36.4 1.8 0.0012 18.1 1.1 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK62582.1 - 3.6e-08 33.0 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK62582.1 - 1.3e-07 31.5 3.7 4.7e-07 29.7 2.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK62582.1 - 3e-06 26.6 0.3 5.3e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK62582.1 - 7e-06 26.2 1.1 1.6e-05 25.0 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK62582.1 - 0.0013 18.1 0.2 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KIK62582.1 - 0.0019 17.0 0.7 0.0048 15.7 0.9 1.5 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.18 KIK62582.1 - 0.0033 17.3 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KIK62582.1 - 0.0034 17.4 0.0 0.041 13.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK62582.1 - 0.0044 17.5 0.3 0.028 15.0 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK62582.1 - 0.0074 15.4 0.5 0.012 14.7 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIK62582.1 - 0.016 14.3 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KIK62582.1 - 0.03 13.9 0.2 0.051 13.1 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KIK62582.1 - 0.068 12.4 0.3 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIK62582.1 - 0.086 12.1 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK62582.1 - 0.11 12.9 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK62582.1 - 0.18 11.1 0.3 0.32 10.3 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIK62582.1 - 0.22 10.8 2.8 0.42 9.9 2.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK62582.1 - 0.23 10.3 0.0 0.79 8.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.21 KIK62583.1 - 9.4e-68 228.2 0.0 1.3e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KIK62583.1 - 2.3e-20 73.6 0.0 5e-20 72.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KIK62583.1 - 3.4e-07 30.7 0.1 7.4e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KIK62583.1 - 0.0061 17.0 0.0 0.04 14.4 0.0 2.4 3 1 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIK62583.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KIK62585.1 - 2.6e-47 160.5 0.0 3.7e-46 156.7 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIK62585.1 - 1.7e-38 132.1 0.0 2.8e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KIK62585.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-ISL3 PF14690.6 KIK62586.1 - 0.16 12.7 0.4 0.58 10.9 0.4 2.0 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PI3Ka PF00613.20 KIK62587.1 - 3.4e-51 173.3 0.0 5.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KIK62587.1 - 2.9e-46 158.3 0.0 1.8e-30 106.5 0.0 2.7 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KIK62587.1 - 5.9e-39 133.2 0.0 1e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Peptidase_M20 PF01546.28 KIK62590.1 - 8.6e-31 107.2 0.0 1.3e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK62590.1 - 2.2e-09 37.2 0.0 1e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK62590.1 - 4.5e-05 23.2 0.0 0.00012 21.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK62592.1 - 1.8e-30 106.2 0.0 2.7e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK62592.1 - 3.1e-09 36.7 0.1 2e-08 34.1 0.1 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK62592.1 - 0.0002 21.1 0.1 0.00054 19.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Glyco_hydro_18 PF00704.28 KIK62594.1 - 1.3e-13 51.4 0.0 1.7e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SH3_9 PF14604.6 KIK62595.1 - 3.3e-13 49.3 0.2 5.1e-13 48.6 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK62595.1 - 3e-11 42.8 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK62595.1 - 3.8e-11 42.4 0.5 5.5e-11 41.9 0.5 1.3 1 0 0 1 1 1 1 SH3 domain PARP PF00644.20 KIK62596.1 - 0.0091 15.6 0.7 0.25 10.9 0.0 2.7 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain DZR PF12773.7 KIK62596.1 - 0.19 11.7 7.1 1.5 8.9 0.3 2.8 2 0 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.6 KIK62596.1 - 0.27 11.7 9.0 0.91 9.9 0.4 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar RPAP2_Rtr1 PF04181.13 KIK62596.1 - 3.9 7.9 8.1 0.5 10.7 0.7 2.8 2 1 1 3 3 3 0 Rtr1/RPAP2 family NACHT PF05729.12 KIK62597.1 - 0.0091 15.9 0.1 0.04 13.8 0.0 1.9 1 1 0 2 2 2 1 NACHT domain NACHT PF05729.12 KIK62598.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK62598.1 - 0.091 13.1 0.0 0.091 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain zf-CCHC PF00098.23 KIK62600.1 - 0.00081 19.4 1.1 0.0024 17.9 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle Rota_NS53 PF00981.17 KIK62600.1 - 0.01 14.8 3.1 0.012 14.6 3.1 1.1 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) RVT_3 PF13456.6 KIK62601.1 - 0.045 13.6 0.0 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 Reverse transcriptase-like TauD PF02668.16 KIK62603.1 - 2.5e-36 125.8 0.2 5e-22 79.0 0.1 2.3 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIK62603.1 - 1.6e-15 57.5 0.3 1.3e-13 51.3 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF971) CsiD PF08943.10 KIK62603.1 - 0.0083 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 CsiD HoxA13_N PF12284.8 KIK62604.1 - 0.14 12.8 0.1 0.2 12.3 0.1 1.2 1 0 0 1 1 1 0 Hox protein A13 N terminal VHS PF00790.19 KIK62612.1 - 4.2e-37 127.1 0.0 2.2e-36 124.8 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KIK62612.1 - 1.4e-17 63.7 0.1 7.8e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KIK62612.1 - 0.0026 17.3 0.2 0.0089 15.6 0.2 1.9 1 0 0 1 1 1 1 GGA N-GAT domain F-box-like PF12937.7 KIK62613.1 - 0.00022 21.0 3.1 0.00046 20.0 3.1 1.6 1 1 0 1 1 1 1 F-box-like DUF1192 PF06698.11 KIK62613.1 - 0.0055 16.7 0.4 0.008 16.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) SKA2 PF16740.5 KIK62613.1 - 0.034 13.9 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 KIK62613.1 - 0.056 13.2 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KIK62613.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AhpC-TSA PF00578.21 KIK62615.1 - 2.1e-10 40.6 0.0 1.1e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Polyoma_coat2 PF00761.20 KIK62615.1 - 0.027 14.2 0.2 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein FeoB_Cyto PF17910.1 KIK62615.1 - 0.036 14.6 0.9 0.075 13.6 0.1 1.9 2 0 0 2 2 2 0 FeoB cytosolic helical domain DASH_Dam1 PF08653.10 KIK62615.1 - 0.062 13.1 3.7 6.6 6.6 0.2 3.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 SlyX PF04102.12 KIK62615.1 - 0.11 13.2 6.9 13 6.5 0.0 3.6 3 0 0 3 3 3 0 SlyX GerPC PF10737.9 KIK62615.1 - 0.11 12.5 1.0 0.21 11.6 0.3 1.7 2 0 0 2 2 2 0 Spore germination protein GerPC RPW8 PF05659.11 KIK62615.1 - 0.63 9.7 5.4 0.14 11.9 0.4 2.3 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NUDIX PF00293.28 KIK62616.1 - 5.9e-08 32.8 0.0 1.7e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Trp_halogenase PF04820.14 KIK62617.1 - 0.02 13.7 0.0 6.8 5.4 0.0 2.9 2 1 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.7 KIK62617.1 - 0.21 10.9 0.0 1.2 8.4 0.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF563 PF04577.14 KIK62619.1 - 2.8e-26 93.0 0.4 7.2e-26 91.6 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) NUDIX PF00293.28 KIK62620.1 - 4.4e-09 36.5 0.0 1.1e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain AMP-binding PF00501.28 KIK62621.1 - 2.1e-83 280.3 0.0 2.7e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK62621.1 - 1.7e-12 48.1 0.0 4.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1748 PF08520.10 KIK62622.1 - 8.8e-23 80.0 0.0 9.7e-23 79.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) LSPR PF06049.12 KIK62622.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Coagulation Factor V LSPD Repeat DHDPS PF00701.22 KIK62623.1 - 1.2e-32 112.8 0.0 2.1e-32 112.0 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KIK62623.1 - 0.032 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase PUD1_2 PF18457.1 KIK62623.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 Sipho_Gp37 PF14594.6 KIK62623.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein NACHT PF05729.12 KIK62624.1 - 1.6e-12 47.6 1.2 1.4e-10 41.3 0.5 2.9 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK62624.1 - 1.1e-06 29.1 0.0 4e-06 27.3 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK62624.1 - 0.00039 20.9 0.0 0.0023 18.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK62624.1 - 0.0012 19.2 0.0 0.0043 17.4 0.0 2.0 1 1 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KIK62624.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK62624.1 - 0.007 16.6 0.2 0.069 13.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KIK62624.1 - 0.0078 15.3 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KIK62624.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK62624.1 - 0.023 14.0 0.2 0.12 11.6 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 KIK62624.1 - 0.025 15.1 0.5 0.33 11.5 0.5 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK62624.1 - 0.031 14.3 0.0 0.32 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK62624.1 - 0.042 13.6 0.0 0.066 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK62624.1 - 0.073 12.8 0.0 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KIK62624.1 - 0.091 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK62624.1 - 0.14 12.4 0.1 0.7 10.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK62624.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DHDPS PF00701.22 KIK62625.1 - 0.03 13.0 0.0 0.037 12.7 0.0 1.0 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family NACHT PF05729.12 KIK62626.1 - 3.7e-09 36.7 0.1 2.3e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK62626.1 - 0.0039 17.6 0.0 0.0097 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KIK62626.1 - 0.033 13.9 0.0 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK62626.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KIK62626.1 - 0.2 12.1 0.0 1.8 9.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Retrotran_gag_2 PF14223.6 KIK62627.1 - 0.0079 15.9 0.6 0.0098 15.6 0.6 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_WhiA PF02650.14 KIK62628.1 - 0.0015 18.9 0.2 0.0025 18.1 0.2 1.3 1 0 0 1 1 1 1 WhiA C-terminal HTH domain Asp_protease_2 PF13650.6 KIK62629.1 - 0.00014 22.5 0.0 0.00045 20.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK62629.1 - 0.00097 19.6 0.0 0.0075 16.8 0.0 2.3 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KIK62629.1 - 0.019 15.2 0.1 0.16 12.3 0.1 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF999 PF06198.11 KIK62630.1 - 0.024 14.6 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF999) HPS6 PF15702.5 KIK62632.1 - 0.11 10.5 0.2 0.16 10.0 0.2 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein Acetyltransf_3 PF13302.7 KIK62634.1 - 4.3e-12 46.9 0.0 5.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK62634.1 - 0.0023 18.1 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Dyp_perox PF04261.12 KIK62635.1 - 1.5e-06 27.4 0.1 5.3e-05 22.4 0.2 2.7 2 2 0 2 2 2 2 Dyp-type peroxidase family Amino_oxidase PF01593.24 KIK62636.1 - 4.7e-37 128.3 0.0 5.9e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK62636.1 - 1.6e-08 34.7 0.2 4.4e-08 33.3 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK62636.1 - 8e-05 22.0 0.2 0.00086 18.6 0.2 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK62636.1 - 0.0038 16.5 0.1 0.0078 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK62636.1 - 0.0038 16.0 0.2 0.0079 14.9 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIK62636.1 - 0.04 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK62636.1 - 0.07 12.2 0.6 0.19 10.8 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KIK62636.1 - 0.098 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK62636.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KIK62636.1 - 0.14 11.2 0.2 0.42 9.6 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Dyp_perox PF04261.12 KIK62637.1 - 4.3e-08 32.5 0.1 6.5e-07 28.6 0.1 2.6 2 1 0 2 2 2 1 Dyp-type peroxidase family DHDPS PF00701.22 KIK62638.1 - 1.5e-22 79.7 0.0 1.9e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3570 PF12094.8 KIK62638.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) PEP_mutase PF13714.6 KIK62638.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.16 KIK62639.1 - 3.3e-18 65.7 71.2 1.2e-13 50.7 40.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK62639.1 - 5.4e-06 25.5 27.7 0.0044 15.9 9.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Y2_Tnp PF04986.13 KIK62640.1 - 0.13 12.2 1.4 0.24 11.5 1.4 1.3 1 0 0 1 1 1 0 Putative transposase COesterase PF00135.28 KIK62641.1 - 1.1e-86 291.8 0.0 1.5e-86 291.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK62641.1 - 5.7e-06 26.3 0.1 1.7e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold RRM_1 PF00076.22 KIK62644.1 - 0.0079 16.0 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA PF00578.21 KIK62646.1 - 8.5e-09 35.4 0.0 4.1e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family RPW8 PF05659.11 KIK62646.1 - 0.015 14.9 0.5 0.015 14.9 0.5 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FeoB_Cyto PF17910.1 KIK62646.1 - 0.041 14.4 0.3 0.13 12.9 0.3 1.8 1 0 0 1 1 1 0 FeoB cytosolic helical domain GerPC PF10737.9 KIK62646.1 - 0.1 12.7 1.3 0.15 12.1 0.3 1.7 2 0 0 2 2 2 0 Spore germination protein GerPC SPA PF08616.10 KIK62649.1 - 9.8e-06 25.5 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 KIK62649.1 - 0.091 12.7 0.0 2 8.3 0.0 2.5 1 1 0 1 1 1 0 DENN (AEX-3) domain ERO1 PF04137.15 KIK62650.1 - 1.2e-113 379.9 0.0 1.4e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Glyco_hydro_43 PF04616.14 KIK62651.1 - 5.4e-11 42.3 0.7 1.2e-10 41.2 0.5 1.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 AhpC-TSA PF00578.21 KIK62652.1 - 4.4e-09 36.3 0.0 2.6e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family DASH_Dam1 PF08653.10 KIK62652.1 - 0.0061 16.3 4.6 0.34 10.8 0.3 2.8 2 0 0 2 2 2 2 DASH complex subunit Dam1 FeoB_Cyto PF17910.1 KIK62652.1 - 0.021 15.4 0.3 0.068 13.7 0.3 1.8 1 0 0 1 1 1 0 FeoB cytosolic helical domain RPW8 PF05659.11 KIK62652.1 - 0.044 13.5 0.3 0.044 13.5 0.3 2.5 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Polyoma_coat2 PF00761.20 KIK62652.1 - 0.052 13.3 0.7 0.1 12.3 0.7 1.6 1 0 0 1 1 1 0 Polyomavirus coat protein SlyX PF04102.12 KIK62652.1 - 0.35 11.5 9.3 6.6 7.4 0.9 3.6 3 0 0 3 3 3 0 SlyX 7TM_GPCR_Sri PF10327.9 KIK62653.1 - 0.0052 16.0 0.1 0.0054 16.0 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri UDPGT PF00201.18 KIK62654.1 - 4e-15 55.6 0.0 7.4e-15 54.7 0.1 1.3 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK62654.1 - 0.047 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DASH_Dam1 PF08653.10 KIK62655.1 - 0.2 11.5 0.2 0.63 9.9 0.2 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 RT_RNaseH PF17917.1 KIK62656.1 - 7e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KIK62656.1 - 0.041 13.9 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase HNF-1_N PF04814.13 KIK62659.1 - 2.7 8.5 5.4 3.1 8.4 5.4 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PRCC PF10253.9 KIK62659.1 - 2.8 8.7 9.4 4.1 8.1 9.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ABC_tran_CTD PF16326.5 KIK62663.1 - 3.3e-06 27.3 14.6 0.034 14.4 0.7 3.6 2 1 1 3 3 3 3 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 KIK62663.1 - 0.0004 20.3 23.5 0.00051 20.0 1.7 3.5 3 1 0 3 3 3 1 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 KIK62663.1 - 0.00044 20.6 1.0 0.00044 20.6 1.0 3.0 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CCDC144C PF14915.6 KIK62663.1 - 0.0013 17.9 0.9 0.0013 17.9 0.9 2.2 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DUF5082 PF16888.5 KIK62663.1 - 0.0043 17.3 10.3 0.19 12.0 3.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) FlxA PF14282.6 KIK62663.1 - 0.0044 17.0 10.2 0.36 10.9 0.3 2.4 2 0 0 2 2 2 2 FlxA-like protein DUF4140 PF13600.6 KIK62663.1 - 0.01 16.2 7.8 0.079 13.4 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SKA1 PF07160.12 KIK62663.1 - 0.013 15.3 8.4 0.34 10.7 0.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4472 PF14739.6 KIK62663.1 - 0.015 16.0 1.2 0.015 16.0 1.2 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4472) Lzipper-MIP1 PF14389.6 KIK62663.1 - 0.015 15.5 9.0 0.23 11.8 0.4 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF5595 PF18077.1 KIK62663.1 - 0.016 15.3 1.1 0.016 15.3 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) APG6_N PF17675.1 KIK62663.1 - 0.019 15.5 0.9 0.019 15.5 0.9 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KIK62663.1 - 0.027 14.7 17.2 0.077 13.2 0.5 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 GPS2_interact PF15784.5 KIK62663.1 - 0.039 14.4 13.7 0.64 10.5 0.2 2.7 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF3156 PF11354.8 KIK62663.1 - 0.067 13.1 0.9 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) GrpE PF01025.19 KIK62663.1 - 0.071 12.8 12.9 0.086 12.5 1.4 2.3 2 0 0 2 2 2 0 GrpE MbeD_MobD PF04899.12 KIK62663.1 - 0.091 12.9 2.5 0.16 12.1 0.1 2.4 2 0 0 2 2 2 0 MbeD/MobD like DUF3450 PF11932.8 KIK62663.1 - 0.1 11.9 9.7 0.4 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 KIK62663.1 - 0.11 12.6 0.5 5.9 6.9 0.0 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KIK62663.1 - 0.11 12.8 9.2 0.21 11.9 0.3 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KIK62663.1 - 0.11 12.9 3.0 0.89 10.1 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KIK62663.1 - 0.16 11.3 16.1 0.28 10.5 1.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KIK62663.1 - 0.17 12.1 12.3 4.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 KIK62663.1 - 0.17 12.2 15.0 0.13 12.6 6.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KIK62663.1 - 0.18 11.6 12.4 0.37 10.6 0.4 2.8 2 1 0 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.13 KIK62663.1 - 0.18 12.3 11.8 0.5 10.8 0.2 2.7 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MctB PF11382.8 KIK62663.1 - 0.18 11.4 3.3 0.34 10.6 0.1 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Lebercilin PF15619.6 KIK62663.1 - 0.21 11.2 20.9 0.39 10.3 9.2 2.8 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 KIK62663.1 - 0.24 11.1 13.8 0.33 10.7 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1192 PF06698.11 KIK62663.1 - 0.24 11.5 8.1 0.27 11.3 2.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) STAT_alpha PF01017.20 KIK62663.1 - 0.31 10.9 12.7 5.6 6.8 0.1 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Filament PF00038.21 KIK62663.1 - 0.32 10.5 15.7 0.27 10.8 0.7 2.2 2 0 0 2 2 2 0 Intermediate filament protein zf-CpG_bind_C PF12269.8 KIK62663.1 - 0.34 10.6 8.8 2.7 7.7 3.7 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Med4 PF10018.9 KIK62663.1 - 0.36 10.5 13.1 1.4 8.6 0.6 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 ADIP PF11559.8 KIK62663.1 - 0.43 10.7 17.1 0.14 12.2 0.9 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding HTH_35 PF13693.6 KIK62663.1 - 0.58 10.2 2.7 2.4 8.3 0.4 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2408 PF10303.9 KIK62663.1 - 0.58 10.7 10.6 3.2 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) HAUS-augmin3 PF14932.6 KIK62663.1 - 0.63 9.6 13.6 4 6.9 0.5 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4094 PF13334.6 KIK62663.1 - 0.63 10.5 8.9 0.93 10.0 0.7 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4094) CASP_C PF08172.12 KIK62663.1 - 0.66 9.3 11.0 0.41 10.0 2.0 2.1 2 0 0 2 2 2 0 CASP C terminal Prefoldin_2 PF01920.20 KIK62663.1 - 0.74 9.8 15.3 0.21 11.6 0.9 2.9 2 1 0 2 2 2 0 Prefoldin subunit TRAF_BIRC3_bd PF16673.5 KIK62663.1 - 0.74 9.6 12.1 2.2 8.2 0.1 3.1 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Phasin PF05597.11 KIK62663.1 - 0.8 9.7 7.7 8.2 6.5 2.5 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Csm1_N PF18504.1 KIK62663.1 - 0.92 9.9 14.0 0.19 12.1 1.5 2.7 2 1 0 2 2 2 0 Csm1 N-terminal domain Cluap1 PF10234.9 KIK62663.1 - 1 8.7 15.7 0.27 10.6 0.6 2.3 2 1 0 2 2 2 0 Clusterin-associated protein-1 DUF2203 PF09969.9 KIK62663.1 - 1.1 10.0 9.4 2.5 8.9 4.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 KIK62663.1 - 1.1 9.2 16.7 0.13 12.2 0.5 2.8 2 1 0 2 2 2 0 Axonemal dynein light chain DUF4391 PF14335.6 KIK62663.1 - 1.2 8.8 9.5 1.4 8.6 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) CENP-Q PF13094.6 KIK62663.1 - 1.3 9.2 15.1 2.2 8.5 1.6 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DLP_helical PF18709.1 KIK62663.1 - 1.3 8.1 9.7 1.7 7.8 3.9 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain Spc7 PF08317.11 KIK62663.1 - 1.4 7.7 17.0 0.64 8.9 0.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GTA_holin_3TM PF11351.8 KIK62663.1 - 1.5 9.4 5.5 2.1 8.9 1.1 2.4 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release YlqD PF11068.8 KIK62663.1 - 1.5 9.2 13.4 1.5 9.2 0.4 2.3 2 0 0 2 2 2 0 YlqD protein Osmo_CC PF08946.10 KIK62663.1 - 2.2 8.6 8.4 1 9.7 0.1 2.7 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Prefoldin PF02996.17 KIK62663.1 - 2.2 8.2 12.0 0.92 9.4 0.4 3.0 2 1 1 3 3 3 0 Prefoldin subunit Snf7 PF03357.21 KIK62663.1 - 2.3 7.8 15.8 7.5 6.1 0.7 3.4 2 1 0 2 2 2 0 Snf7 Fzo_mitofusin PF04799.13 KIK62663.1 - 2.7 7.5 9.2 4.4 6.8 3.7 2.4 2 1 0 2 2 2 0 fzo-like conserved region BRE1 PF08647.11 KIK62663.1 - 3.3 7.8 17.2 0.24 11.5 1.0 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase BRI3BP PF14965.6 KIK62663.1 - 3.9 7.0 5.2 0.97 8.9 0.1 2.3 2 1 1 3 3 3 0 Negative regulator of p53/TP53 CC2-LZ PF16516.5 KIK62663.1 - 4.3 7.8 13.9 0.2 12.0 0.6 2.7 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ERM PF00769.19 KIK62663.1 - 4.3 7.1 20.0 14 5.4 19.9 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4200 PF13863.6 KIK62663.1 - 4.4 7.7 20.9 7.5 7.0 2.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ACCA PF03255.14 KIK62663.1 - 5 7.0 8.3 9.4 6.1 2.9 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit UPF0242 PF06785.11 KIK62663.1 - 5.3 7.1 16.1 6.6 6.8 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KIK62663.1 - 5.3 7.6 12.4 6.1 7.4 0.4 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 Tropomyosin_1 PF12718.7 KIK62663.1 - 6.4 6.9 19.6 0.35 11.0 0.9 2.6 2 1 0 2 2 2 0 Tropomyosin like SlyX PF04102.12 KIK62663.1 - 6.6 7.4 11.0 2.2 9.0 0.1 3.2 2 1 1 3 3 3 0 SlyX LapA_dom PF06305.11 KIK62663.1 - 7.8 6.4 9.6 1.2 9.0 0.1 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF641 PF04859.12 KIK62663.1 - 8.2 6.8 13.0 5.4 7.4 6.6 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KIK62663.1 - 9.5 6.7 11.1 4.8 7.6 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.15 KIK62663.1 - 9.9 6.6 13.2 26 5.3 8.4 2.9 2 1 1 3 3 2 0 Vesicle transport v-SNARE protein N-terminus Hira PF07569.11 KIK62664.1 - 3.1e-15 56.5 0.0 4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 TUP1-like enhancer of split YcaO_C PF18381.1 KIK62664.1 - 0.25 11.2 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Cellulase PF00150.18 KIK62666.1 - 5.9e-27 94.8 0.8 8.6e-27 94.3 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK62666.1 - 1.6e-12 47.1 3.1 1.6e-12 47.1 3.1 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KIK62666.1 - 4.2e-05 22.8 0.0 0.00015 21.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KIK62666.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 KIK62667.1 - 2.3e-23 83.0 0.9 3.7e-23 82.4 0.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK62667.1 - 8.1e-13 48.1 6.6 8.1e-13 48.1 6.6 2.9 4 0 0 4 4 4 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KIK62667.1 - 0.00039 19.6 0.0 0.00072 18.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KIK62667.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.5 1 1 0 1 1 1 0 Beta-galactosidase TraX PF05857.11 KIK62668.1 - 0.93 9.5 8.6 2.1 8.4 8.6 1.7 1 1 0 1 1 1 0 TraX protein Inhibitor_I66 PF16850.5 KIK62669.1 - 2.4e-26 92.3 0.0 2.7e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 zf-C3HC4_3 PF13920.6 KIK62672.1 - 3.2e-06 26.9 6.4 3.2e-06 26.9 6.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 KIK62672.1 - 0.082 12.7 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK62672.1 - 1 10.0 13.2 5.9 7.6 1.6 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-RING_2 PF13639.6 KIK62672.1 - 3.2 8.2 19.6 0.74 10.2 8.4 2.6 2 0 0 2 2 2 0 Ring finger domain Retrotran_gag_2 PF14223.6 KIK62673.1 - 6.2e-09 35.6 0.5 1.6e-08 34.3 0.2 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KIK62673.1 - 0.25 11.1 2.8 0.42 10.4 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK62673.1 - 0.99 9.6 6.0 2.2 8.5 6.0 1.6 1 0 0 1 1 1 0 Zinc knuckle NPIP PF06409.11 KIK62674.1 - 0.12 11.4 0.6 0.21 10.6 0.6 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Peptidase_C14 PF00656.22 KIK62677.1 - 1.4e-19 71.0 0.0 2.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIK62677.1 - 0.16 12.0 0.0 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 KIK62678.1 - 3.8e-22 79.4 0.0 9e-22 78.2 0.0 1.5 2 0 0 2 2 2 1 Caspase domain DUF5623 PF18536.1 KIK62680.1 - 0.058 13.7 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Glyco_transf_8 PF01501.20 KIK62682.1 - 8.8e-13 48.4 0.0 1.8e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_C14 PF00656.22 KIK62683.1 - 1.9e-15 57.5 0.0 1.2e-13 51.7 0.0 2.3 1 1 0 1 1 1 1 Caspase domain FecCD PF01032.18 KIK62685.1 - 0.11 11.5 8.4 0.05 12.6 4.9 1.9 1 1 1 2 2 2 0 FecCD transport family Fun_ATP-synt_8 PF05933.13 KIK62687.1 - 0.26 11.5 5.6 1.1 9.5 5.6 2.2 1 1 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) DUF5408 PF17402.2 KIK62688.1 - 0.039 13.8 0.3 0.089 12.7 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Methyltransf_2 PF00891.18 KIK62690.1 - 3.4e-21 75.5 0.0 2.5e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain RPA_C PF08784.11 KIK62690.1 - 0.01 16.4 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal HTH_Mga PF08280.11 KIK62690.1 - 0.014 15.4 0.0 0.093 12.8 0.0 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain MTS PF05175.14 KIK62690.1 - 0.089 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Trp_halogenase PF04820.14 KIK62692.1 - 5.8e-33 114.4 0.5 4.8e-16 58.7 0.6 3.0 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK62692.1 - 1.9e-14 53.7 0.0 9.2e-14 51.4 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KIK62692.1 - 7.8e-08 32.1 0.1 1.8e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK62692.1 - 1.2e-05 25.4 0.1 5.1e-05 23.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK62692.1 - 1.6e-05 24.3 0.0 3.6e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK62692.1 - 3.9e-05 23.4 0.2 0.012 15.3 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK62692.1 - 0.00062 18.6 0.1 0.0011 17.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KIK62692.1 - 0.00073 18.7 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK62692.1 - 0.0009 18.4 0.1 0.0026 16.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIK62692.1 - 0.023 14.0 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KIK62692.1 - 0.033 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIK62692.1 - 0.12 11.6 0.2 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK62692.1 - 0.17 10.9 0.4 0.26 10.3 0.4 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.22 KIK62693.1 - 5.9e-72 242.9 0.0 1.7e-71 241.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIK62695.1 - 1.1e-26 93.6 49.9 1.8e-21 76.5 40.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KIK62695.1 - 0.19 9.9 14.2 0.32 9.3 14.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Aminotran_5 PF00266.19 KIK62697.1 - 3.2e-39 134.9 0.0 1.9e-31 109.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF3530 PF12048.8 KIK62697.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) p450 PF00067.22 KIK62698.1 - 5.2e-82 276.0 0.0 6.6e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK62699.1 - 2.9e-33 113.4 23.0 6.4e-06 26.8 0.0 9.6 9 1 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62699.1 - 3.8e-25 88.0 0.4 0.005 17.1 0.0 7.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK62699.1 - 2e-09 36.9 0.0 1.1 8.1 0.0 6.9 3 1 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK62699.1 - 0.00019 20.8 0.0 1.6 8.0 0.0 3.5 4 1 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 KIK62699.1 - 0.00063 18.5 6.3 0.96 8.0 0.0 4.3 4 2 2 6 6 6 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK62699.1 - 0.0018 18.2 2.3 3.4 7.7 0.0 5.3 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KIK62699.1 - 0.041 14.4 3.0 4.1 8.0 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain PQQ PF01011.21 KIK62699.1 - 0.11 12.5 0.5 2.5 8.2 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat FBA PF04300.13 KIK62699.1 - 0.15 11.7 0.0 9.8 5.8 0.0 2.3 2 0 0 2 2 2 0 F-box associated region IKI3 PF04762.12 KIK62699.1 - 0.24 9.3 0.2 1.3 6.9 0.0 1.9 2 0 0 2 2 2 0 IKI3 family BTB PF00651.31 KIK62700.1 - 0.09 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 BTB/POZ domain Presenilin PF01080.17 KIK62702.1 - 0.42 9.3 4.7 0.18 10.6 1.0 1.9 2 0 0 2 2 2 0 Presenilin UCH PF00443.29 KIK62703.1 - 7.6e-23 81.3 0.0 9e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK62703.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 KIK62704.1 - 2.9e-23 81.7 18.4 4.9e-05 24.0 0.0 7.7 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62704.1 - 1.1e-11 44.9 0.4 0.0064 16.8 0.0 4.9 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK62704.1 - 8.8e-06 24.9 0.1 3.4 6.5 0.0 4.1 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK62704.1 - 7.8e-05 23.0 0.2 0.0022 18.4 0.0 3.1 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KIK62704.1 - 0.039 12.6 0.3 10 4.6 0.0 3.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK62704.1 - 0.19 11.0 0.0 0.94 8.7 0.0 2.1 1 1 0 1 1 1 0 WD40-like domain WD40 PF00400.32 KIK62705.1 - 2.9e-31 107.0 19.3 3.7e-06 27.6 0.0 7.5 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62705.1 - 2.2e-22 79.2 0.8 0.003 17.8 0.0 6.0 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK62705.1 - 1.2e-09 37.6 0.1 0.67 8.9 0.0 5.9 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK62705.1 - 2.9e-06 26.9 0.0 0.12 11.7 0.0 3.8 2 2 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 KIK62705.1 - 2.3e-05 23.3 2.4 0.24 10.0 0.0 4.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK62705.1 - 5.3e-05 23.0 9.4 1.8 8.6 0.0 6.0 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KIK62705.1 - 0.005 14.9 0.2 1.8 6.5 0.0 2.3 1 1 0 2 2 2 2 IKI3 family FBA PF04300.13 KIK62705.1 - 0.0079 15.9 0.0 4.9 6.8 0.0 2.4 2 0 0 2 2 2 2 F-box associated region PQQ_2 PF13360.6 KIK62705.1 - 0.009 15.6 1.4 0.045 13.3 0.3 2.5 1 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KIK62705.1 - 0.051 13.5 0.3 1.3 9.1 0.1 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat ArlS_N PF18719.1 KIK62705.1 - 0.2 11.9 0.0 17 5.6 0.0 2.5 2 1 0 2 2 2 0 ArlS sensor domain Amidase PF01425.21 KIK62706.1 - 2.7e-85 287.0 0.0 6.4e-85 285.8 0.0 1.5 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 KIK62707.1 - 1.4e-32 113.0 27.0 1.4e-32 113.0 27.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK62707.1 - 2.7e-30 105.6 21.5 1e-29 103.7 21.5 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Fucokinase PF07959.12 KIK62710.1 - 0.021 13.8 0.1 0.089 11.7 0.1 1.8 1 1 1 2 2 2 0 L-fucokinase F-box-like PF12937.7 KIK62711.1 - 5.5e-05 23.0 0.3 0.00018 21.3 0.3 1.9 1 1 0 1 1 1 1 F-box-like DUF4349 PF14257.6 KIK62711.1 - 0.02 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ABC_tran_CTD PF16326.5 KIK62711.1 - 0.033 14.4 0.1 0.057 13.7 0.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 KIK62711.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) AKNA PF12443.8 KIK62711.1 - 0.17 12.5 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor Cytochrom_C_2 PF01322.20 KIK62712.1 - 0.028 15.3 0.8 0.054 14.4 0.4 1.6 2 0 0 2 2 2 0 Cytochrome C' BA14K PF07886.11 KIK62715.1 - 0.57 10.1 4.6 1.6 8.7 4.6 1.7 1 0 0 1 1 1 0 BA14K-like protein ADH_zinc_N PF00107.26 KIK62716.1 - 6e-10 39.2 0.0 9.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK62716.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MAF_flag10 PF01973.18 KIK62716.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 F-box-like PF12937.7 KIK62717.1 - 6.6e-08 32.3 4.1 1.8e-07 30.9 4.1 1.8 1 1 0 1 1 1 1 F-box-like ARD PF03079.14 KIK62718.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 1 0 1 1 1 0 ARD/ARD' family FMO-like PF00743.19 KIK62719.1 - 1.3e-20 73.3 0.0 3.1e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK62719.1 - 5e-20 72.0 0.0 1.9e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK62719.1 - 4e-15 55.8 0.2 3.9e-12 46.0 0.0 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK62719.1 - 1e-12 47.9 0.0 0.0011 18.3 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK62719.1 - 0.00015 22.2 0.1 0.2 12.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK62719.1 - 0.0018 18.3 1.4 1.3 9.0 0.0 3.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIK62719.1 - 0.0022 17.4 0.1 0.39 10.0 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KIK62719.1 - 0.0083 15.3 0.1 0.33 10.0 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK62719.1 - 0.015 15.5 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIK62719.1 - 0.04 14.3 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 KIK62719.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 KIK62719.1 - 0.044 12.9 0.1 0.2 10.7 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 KIK62719.1 - 0.057 12.7 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KIK62719.1 - 0.065 12.8 0.0 0.44 10.1 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK62719.1 - 0.089 11.5 0.2 0.32 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KIK62719.1 - 0.13 11.3 0.0 3.4 6.6 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein HARP PF07443.13 KIK62719.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) Shikimate_DH PF01488.20 KIK62719.1 - 0.17 11.9 0.0 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Prok-JAB PF14464.6 KIK62721.1 - 0.099 12.4 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain F-box-like PF12937.7 KIK62722.1 - 5.7e-09 35.7 0.7 1.9e-08 34.1 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK62722.1 - 0.0008 19.2 0.5 0.0008 19.2 0.5 1.7 2 0 0 2 2 2 1 F-box domain Syntaxin-6_N PF09177.11 KIK62722.1 - 0.078 13.5 0.1 0.25 11.9 0.1 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Csm1_N PF18504.1 KIK62722.1 - 0.095 13.1 0.5 0.15 12.4 0.5 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain RasGAP_C PF03836.15 KIK62722.1 - 0.11 12.7 0.3 0.14 12.3 0.3 1.1 1 0 0 1 1 1 0 RasGAP C-terminus Prefoldin PF02996.17 KIK62722.1 - 0.14 12.0 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit zf-C4H2 PF10146.9 KIK62723.1 - 4.3e-08 33.7 10.0 4.3e-08 33.7 10.0 3.0 2 2 0 2 2 2 1 Zinc finger-containing protein Abhydrolase_6 PF12697.7 KIK62724.1 - 1.5e-11 45.3 0.0 3e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK62724.1 - 0.35 10.5 1.7 3.3 7.3 0.3 2.7 2 2 0 2 2 2 0 alpha/beta hydrolase fold F-box-like PF12937.7 KIK62725.1 - 8.6e-10 38.4 1.9 2.6e-09 36.8 1.9 1.9 1 0 0 1 1 1 1 F-box-like FMO-like PF00743.19 KIK62726.1 - 6.3e-24 84.3 0.0 3e-23 82.1 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK62726.1 - 2.2e-22 79.7 0.0 6.4e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK62726.1 - 8.2e-16 58.1 0.0 3.6e-10 39.6 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK62726.1 - 2.5e-13 49.9 0.0 1e-10 41.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK62726.1 - 2.2e-06 28.1 0.0 0.15 12.6 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIK62726.1 - 1e-05 25.0 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KIK62726.1 - 6.8e-05 22.6 0.0 0.37 10.3 0.0 3.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK62726.1 - 0.00038 20.5 2.0 0.081 12.9 0.1 3.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK62726.1 - 0.00045 19.4 0.1 1.3 8.0 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK62726.1 - 0.00051 19.2 0.0 0.17 10.9 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 KIK62726.1 - 0.00052 20.1 0.1 0.3 11.1 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KIK62726.1 - 0.00056 20.1 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK62726.1 - 0.0009 18.4 0.4 1.2 8.2 0.0 3.6 4 0 0 4 4 4 1 Glucose inhibited division protein A TrkA_N PF02254.18 KIK62726.1 - 0.0015 18.7 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.18 KIK62726.1 - 0.0024 17.8 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK62726.1 - 0.004 16.4 0.2 0.08 12.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK62726.1 - 0.016 13.9 0.4 0.36 9.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KIK62726.1 - 0.14 11.4 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HARP PF07443.13 KIK62726.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) IlvN PF07991.12 KIK62726.1 - 0.18 11.4 0.1 0.63 9.6 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amidase PF01425.21 KIK62727.1 - 6.1e-83 279.3 0.0 4.6e-81 273.1 0.0 2.0 1 1 0 1 1 1 1 Amidase FMO-like PF00743.19 KIK62728.1 - 7.6e-23 80.7 0.0 1.7e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK62728.1 - 1.4e-22 80.3 0.0 1.5e-20 73.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK62728.1 - 2.3e-16 59.9 0.0 2.3e-11 43.5 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK62728.1 - 2e-13 50.2 0.0 7e-11 41.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KIK62728.1 - 2.8e-06 26.8 0.2 0.032 13.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIK62728.1 - 5.9e-06 26.7 0.1 0.047 14.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK62728.1 - 0.00015 21.8 0.1 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KIK62728.1 - 0.00034 20.3 0.0 0.94 9.0 0.0 2.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK62728.1 - 0.00035 19.8 1.0 0.22 10.6 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KIK62728.1 - 0.00043 20.3 2.4 0.08 12.9 0.1 2.7 3 1 0 3 3 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KIK62728.1 - 0.0005 19.3 1.5 0.7 8.9 0.0 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK62728.1 - 0.0014 18.8 0.0 0.075 13.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KIK62728.1 - 0.0018 18.5 0.1 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.18 KIK62728.1 - 0.0049 16.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK62728.1 - 0.0071 15.6 0.5 0.06 12.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK62728.1 - 0.012 14.4 1.7 0.25 10.0 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KIK62728.1 - 0.026 13.6 0.1 1.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KIK62728.1 - 0.034 13.4 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ARD PF03079.14 KIK62729.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family ARD PF03079.14 KIK62733.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_1 PF00190.22 KIK62733.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin ARD PF03079.14 KIK62735.1 - 0.00013 22.2 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Glyco_hydro_61 PF03443.14 KIK62736.1 - 2.3e-53 181.2 0.0 2.8e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KIK62736.1 - 4.2e-13 49.0 9.9 4.2e-13 49.0 9.9 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF3123 PF11321.8 KIK62736.1 - 0.13 12.9 5.3 0.23 12.1 4.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Glyco_hydro_61 PF03443.14 KIK62737.1 - 3.4e-54 183.9 0.1 4.1e-54 183.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KIK62737.1 - 1.1e-11 44.4 12.2 1.1e-11 44.4 12.2 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KIK62737.1 - 0.89 9.9 2.9 1.2 9.5 0.5 2.1 2 0 0 2 2 2 0 Toxin 7 LRR_4 PF12799.7 KIK62739.1 - 0.36 11.3 9.8 2.1 8.9 0.0 5.3 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK62739.1 - 1.7 9.5 3.8 2.2e+02 3.1 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4064 PF13273.6 KIK62740.1 - 0.77 10.1 6.6 5.5 7.3 6.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) ECF_trnsprt PF12822.7 KIK62742.1 - 0.023 14.8 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 ECF transporter, substrate-specific component COX4 PF02936.14 KIK62745.1 - 0.026 14.6 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV ABM PF03992.16 KIK62746.1 - 8.5e-07 29.0 0.1 0.00012 22.1 0.1 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 KIK62746.1 - 0.0032 17.8 0.1 0.46 10.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) NitrOD1 PF18549.1 KIK62746.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Nitrosopumilus output domain 1 DUF4937 PF16291.5 KIK62746.1 - 0.034 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 UCR_UQCRX_QCR9 PF05365.12 KIK62747.1 - 0.12 12.4 1.5 0.19 11.7 1.5 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Phlebovirus_NSM PF07246.11 KIK62747.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M KxDL PF10241.9 KIK62747.1 - 0.16 12.2 1.3 0.43 10.9 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Tropomyosin PF00261.20 KIK62747.1 - 0.16 11.3 5.6 0.38 10.1 5.6 1.6 1 1 0 1 1 1 0 Tropomyosin MtrE PF04206.12 KIK62749.1 - 0.065 12.6 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E Phage_integrase PF00589.22 KIK62750.1 - 0.037 13.8 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family Fungal_KA1 PF16797.5 KIK62752.1 - 0.069 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal kinase associated-1 domain HLH PF00010.26 KIK62753.1 - 1.9e-08 34.2 1.6 1.9e-08 34.2 1.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NpwBP PF12622.7 KIK62753.1 - 0.036 14.8 0.9 0.12 13.1 0.9 1.9 1 0 0 1 1 1 0 mRNA biogenesis factor Glyco_hydro_92 PF07971.12 KIK62755.1 - 1.1e-106 357.6 0.0 1.3e-106 357.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK62755.1 - 9.9e-48 163.1 5.5 1.5e-47 162.5 5.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain adh_short PF00106.25 KIK62756.1 - 1.6e-26 93.0 0.2 4.9e-23 81.6 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK62756.1 - 1.3e-16 60.9 0.0 6.6e-15 55.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK62756.1 - 3.3e-07 30.4 0.2 2e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK62756.1 - 8.8e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK62756.1 - 0.0021 17.5 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase SPO22 PF08631.10 KIK62756.1 - 0.059 12.8 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Remorin_N PF03766.13 KIK62756.1 - 0.14 12.2 0.7 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Remorin, N-terminal region adh_short PF00106.25 KIK62758.1 - 1.8e-11 43.9 0.1 2.3e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK62758.1 - 8e-08 32.4 0.1 9.7e-08 32.1 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK62758.1 - 9e-06 25.4 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KIK62758.1 - 0.0002 20.9 0.0 0.00024 20.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK62758.1 - 0.0091 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KIK62758.1 - 0.013 16.1 0.2 0.019 15.5 0.2 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1491 PF07372.12 KIK62758.1 - 0.013 15.9 0.0 0.029 14.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) Wax2_C PF12076.8 KIK62758.1 - 0.048 13.4 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 WAX2 C-terminal domain 3HCDH_N PF02737.18 KIK62758.1 - 0.066 13.1 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK62758.1 - 0.11 12.5 0.2 1.1 9.3 0.1 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KIK62759.1 - 3.7e-05 23.3 0.1 0.084 12.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase OCC1 PF15506.6 KIK62759.1 - 0.046 13.8 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 OCC1 family FMO-like PF00743.19 KIK62761.1 - 4.9e-18 64.8 0.1 1.3e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK62761.1 - 6.3e-12 45.4 0.0 3.8e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK62761.1 - 1.2e-11 44.4 0.0 8.8e-10 38.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK62761.1 - 1.7e-10 41.0 0.0 7.1e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIK62761.1 - 7.9e-10 38.4 0.0 8e-09 35.1 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK62761.1 - 5.8e-06 26.4 0.0 2.7 8.0 0.1 4.7 5 0 0 5 5 5 2 FAD-NAD(P)-binding DAO PF01266.24 KIK62761.1 - 7.4e-06 25.8 0.1 0.12 12.0 0.0 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK62761.1 - 1.3e-05 25.7 0.0 0.14 12.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK62761.1 - 0.0034 17.5 0.0 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KIK62761.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIK62761.1 - 0.19 12.2 0.0 1.7 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HicB-like_2 PF15970.5 KIK62762.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Med26 PF08711.11 KIK62762.1 - 0.22 11.6 0.5 0.61 10.2 0.5 1.8 1 1 0 1 1 1 0 TFIIS helical bundle-like domain GLTSCR1 PF15249.6 KIK62764.1 - 0.14 12.7 0.1 0.49 10.9 0.0 1.9 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein Hva1_TUDOR PF11160.8 KIK62765.1 - 2.8e-21 75.4 2.5 3.5e-21 75.1 2.5 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain DUF1918 PF08940.11 KIK62765.1 - 0.048 13.3 0.7 1.7 8.3 0.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1918) Fez1 PF06818.15 KIK62766.1 - 0.016 15.6 4.6 0.038 14.5 4.6 1.5 1 0 0 1 1 1 0 Fez1 Cep57_CLD_2 PF14197.6 KIK62766.1 - 0.047 13.8 0.6 0.047 13.8 0.6 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 GPI-anchored PF10342.9 KIK62767.1 - 9.5e-09 35.9 0.1 1.1e-08 35.7 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SCPU PF05229.15 KIK62769.1 - 0.12 12.8 0.7 0.12 12.8 0.7 2.0 2 0 0 2 2 2 0 Spore Coat Protein U domain SRRM_C PF15230.6 KIK62769.1 - 2.3 8.9 0.0 2.3 8.9 0.0 3.1 3 0 0 3 3 3 0 Serine/arginine repetitive matrix protein C-terminus Membrane_bind PF14564.6 KIK62770.1 - 0.26 11.7 1.7 9.4 6.7 0.0 2.6 2 1 1 3 3 3 0 Membrane binding DUF515 PF04415.12 KIK62770.1 - 3.1 6.1 6.1 4.3 5.6 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ARL6IP6 PF15062.6 KIK62771.1 - 2.4 8.3 6.3 12 6.1 0.2 3.0 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix DUF3792 PF12670.7 KIK62774.1 - 0.012 15.8 4.8 0.069 13.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Keratin_assoc PF09775.9 KIK62774.1 - 0.023 14.4 2.2 0.033 13.9 0.3 1.9 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Stevor PF17410.2 KIK62774.1 - 0.036 13.6 0.4 0.045 13.3 0.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 KIK62774.1 - 0.068 14.1 0.0 0.19 12.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KIK62774.1 - 0.071 13.9 0.2 0.28 12.0 0.0 2.2 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Mid2 PF04478.12 KIK62774.1 - 0.095 12.5 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2207 PF09972.9 KIK62774.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 KIK62774.1 - 7.9 6.5 6.7 0.38 10.7 0.7 1.9 2 0 0 2 2 2 0 Syndecan domain Bac_transf PF02397.16 KIK62776.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.3 1 1 0 1 1 1 0 Bacterial sugar transferase FHA PF00498.26 KIK62777.1 - 2.3e-07 31.1 0.0 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KIK62777.1 - 0.061 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain F-box-like PF12937.7 KIK62778.1 - 5.7e-08 32.5 6.0 1.9e-07 30.8 1.3 2.9 2 0 0 2 2 2 2 F-box-like PAP_assoc PF03828.19 KIK62779.1 - 5.4e-16 58.6 0.0 1.5e-15 57.1 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIK62779.1 - 6.1e-10 39.3 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIK62779.1 - 0.024 14.7 0.2 0.051 13.7 0.0 1.6 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase YTH PF04146.15 KIK62780.1 - 3.7e-38 131.1 1.7 1.3e-20 74.0 0.1 2.0 1 1 1 2 2 2 2 YT521-B-like domain TFIID_30kDa PF03540.13 KIK62780.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Peroxidase_ext PF11895.8 KIK62782.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal peroxidase extension region dsrm PF00035.26 KIK62783.1 - 8.7e-09 36.0 0.0 1.6e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KIK62783.1 - 0.00031 20.9 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK62783.1 - 0.025 15.2 0.0 0.11 13.1 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease III domain HTH_30 PF13556.6 KIK62783.1 - 0.03 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain dsrm PF00035.26 KIK62784.1 - 2.2e-08 34.7 0.0 4.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KIK62784.1 - 0.053 14.1 0.0 0.37 11.4 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK62784.1 - 0.069 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease-III-like dsrm PF00035.26 KIK62785.1 - 4.5e-08 33.7 0.0 8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KIK62785.1 - 0.11 13.1 0.0 0.83 10.3 0.0 2.2 1 1 0 1 1 1 0 Ribonuclease III domain p450 PF00067.22 KIK62787.1 - 1.2e-62 212.2 0.0 1.6e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1940 PF09155.10 KIK62788.1 - 0.067 13.3 0.1 0.087 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) KleE PF17394.2 KIK62789.1 - 0.17 12.1 3.5 0.22 11.8 2.3 1.8 1 1 0 1 1 1 0 Uncharacterized KleE stable inheritance protein KleE PF17394.2 KIK62792.1 - 0.073 13.3 2.8 0.19 11.9 2.8 1.8 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein F-box-like PF12937.7 KIK62793.1 - 2e-05 24.4 3.5 3.2e-05 23.7 0.3 2.5 2 0 0 2 2 2 1 F-box-like CE2_N PF17996.1 KIK62795.1 - 0.00017 21.6 0.4 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Mid2 PF04478.12 KIK62795.1 - 0.0033 17.3 0.1 0.0066 16.3 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DcuC PF03606.15 KIK62795.1 - 0.006 15.1 0.3 0.0084 14.6 0.3 1.1 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DUF2207 PF09972.9 KIK62795.1 - 0.019 13.7 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 KIK62795.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 KIK62795.1 - 0.2 11.2 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Lipase_GDSL_2 PF13472.6 KIK62796.1 - 8.7e-09 36.0 0.0 1.2e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK62796.1 - 1.5e-07 31.6 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cyclin PF08613.11 KIK62800.1 - 1.9e-08 34.8 0.0 2.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIK62800.1 - 8.1e-08 32.1 0.0 1.7e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2420 PF10336.9 KIK62801.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) adh_short PF00106.25 KIK62802.1 - 1.2e-37 129.2 0.8 1.9e-37 128.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK62802.1 - 2.2e-36 125.6 0.3 5.3e-36 124.3 0.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK62802.1 - 1.3e-10 41.5 0.5 2.6e-10 40.5 0.3 1.7 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KIK62802.1 - 0.00029 20.3 0.1 0.00049 19.6 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 KIK62802.1 - 0.00034 21.1 2.8 0.022 15.3 0.1 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KIK62802.1 - 0.0014 18.6 0.1 0.003 17.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KIK62802.1 - 0.0022 17.5 0.2 0.011 15.2 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK62802.1 - 0.0063 15.6 0.8 0.034 13.2 0.1 2.2 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIK62802.1 - 0.02 14.0 0.1 0.04 13.0 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 KIK62802.1 - 0.03 14.2 0.2 0.057 13.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ta0938 PF11494.8 KIK62802.1 - 0.046 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 Ta0938 BRCC36_C PF18110.1 KIK62802.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain NAD_binding_7 PF13241.6 KIK62802.1 - 0.13 12.7 0.2 0.39 11.2 0.3 1.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Pkinase PF00069.25 KIK62803.1 - 9.4e-60 202.2 0.0 1.2e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62803.1 - 2.1e-26 92.8 0.0 3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK62803.1 - 1.4e-05 24.6 0.0 0.00068 19.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIK62803.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK62803.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIK62804.1 - 2.6e-65 220.4 0.0 2.9e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62804.1 - 5.7e-29 101.2 0.0 7.1e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK62804.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK62804.1 - 0.0006 18.7 0.0 0.00096 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK62804.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK62804.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.25 KIK62805.1 - 3.8e-42 144.0 0.4 5e-42 143.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK62805.1 - 6.4e-33 114.2 0.1 8.7e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK62805.1 - 6e-12 45.8 1.3 1.2e-10 41.5 1.3 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK62805.1 - 5.2e-06 26.1 1.0 1.2e-05 24.9 1.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK62805.1 - 6.3e-05 22.5 0.1 9.9e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIK62805.1 - 0.005 16.3 0.3 0.056 12.8 0.3 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Methyltransf_31 PF13847.6 KIK62805.1 - 0.0095 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_4 PF13439.6 KIK62805.1 - 0.0096 15.9 0.0 4.4 7.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase Family 4 NAD_binding_10 PF13460.6 KIK62805.1 - 0.01 15.7 0.3 0.021 14.7 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK62805.1 - 0.011 14.9 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_25 PF13649.6 KIK62805.1 - 0.012 16.3 0.0 0.032 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIK62805.1 - 0.018 14.4 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_trans_4_2 PF13477.6 KIK62805.1 - 0.018 15.0 0.1 0.43 10.6 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferase 4-like Polysacc_synt_2 PF02719.15 KIK62805.1 - 0.021 14.0 0.3 0.039 13.1 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein YjeF_N PF03853.15 KIK62805.1 - 0.037 13.9 0.1 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3Beta_HSD PF01073.19 KIK62805.1 - 0.055 12.5 0.4 0.56 9.2 0.1 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KIK62805.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GST_N_3 PF13417.6 KIK62806.1 - 2.4e-12 47.1 0.1 7.2e-12 45.6 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK62806.1 - 9.6e-10 38.6 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK62806.1 - 1.6e-05 25.0 0.0 3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK62806.1 - 1.8e-05 24.8 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK62806.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TrbC PF04956.13 KIK62807.1 - 1.3 9.3 4.6 1.8 8.9 1.1 2.0 1 1 1 2 2 2 0 TrbC/VIRB2 family GST_N_3 PF13417.6 KIK62808.1 - 9.7e-13 48.3 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK62808.1 - 1e-10 41.7 0.0 2.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK62808.1 - 7.4e-06 26.1 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK62808.1 - 1.6e-05 25.0 0.0 4.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK62808.1 - 9.1e-05 22.4 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK62808.1 - 0.079 13.3 0.0 0.65 10.4 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIK62808.1 - 0.12 13.1 0.0 0.51 11.1 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain Hva1_TUDOR PF11160.8 KIK62809.1 - 4.8e-17 61.9 1.3 6e-17 61.6 1.3 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain zf-H2C2_2 PF13465.6 KIK62810.1 - 2.6e-07 30.8 2.1 2.6e-07 30.8 2.1 3.8 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK62810.1 - 2.9e-05 24.5 15.3 0.00068 20.3 3.1 3.9 4 1 0 4 4 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK62810.1 - 6.9e-05 23.1 16.5 0.00019 21.7 3.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK62810.1 - 0.0029 17.8 1.8 0.22 11.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KIK62810.1 - 0.0085 16.2 11.9 0.0085 16.2 11.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.12 KIK62810.1 - 0.011 16.0 5.6 1.5 9.2 0.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KIK62810.1 - 0.011 16.0 0.3 0.011 16.0 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK62810.1 - 0.039 13.9 0.6 0.039 13.9 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1 PF03811.13 KIK62810.1 - 0.18 11.6 9.2 0.54 10.0 9.2 1.9 1 0 0 1 1 1 0 InsA N-terminal domain zf-BED PF02892.15 KIK62810.1 - 0.28 11.2 7.0 0.23 11.5 2.3 2.7 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KIK62810.1 - 0.34 10.7 8.0 0.38 10.5 2.9 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KIK62810.1 - 0.39 11.1 6.3 0.87 10.0 0.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 KIK62810.1 - 7.8 6.6 16.3 4 7.5 1.5 2.3 2 0 0 2 2 2 0 zinc-ribbons PBP1_TM PF14812.6 KIK62811.1 - 0.21 12.0 5.2 0.48 10.8 5.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KIK62811.1 - 0.28 10.5 3.5 0.54 9.5 3.5 1.4 1 0 0 1 1 1 0 NOA36 protein SUIM_assoc PF16619.5 KIK62811.1 - 3.1 7.9 10.6 14 5.9 10.6 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cyclin_N PF00134.23 KIK62812.1 - 1.9e-12 47.0 0.0 2.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK62812.1 - 1.2e-05 25.7 0.0 1.6e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin CsbD PF05532.12 KIK62813.1 - 3.6e-05 23.6 2.4 3.6e-05 23.6 2.4 2.1 2 0 0 2 2 2 1 CsbD-like Gly-zipper_Omp PF13488.6 KIK62813.1 - 0.0077 16.2 16.5 0.0077 16.2 16.5 3.9 3 2 2 5 5 5 2 Glycine zipper Gly-zipper_YMGG PF13441.6 KIK62813.1 - 0.017 14.9 17.6 0.017 14.9 17.6 3.5 2 1 3 5 5 5 0 YMGG-like Gly-zipper Aldo_ket_red PF00248.21 KIK62814.1 - 6.2e-42 143.8 0.1 2.3e-41 141.9 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family HILPDA PF15220.6 KIK62815.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated GST_N_3 PF13417.6 KIK62816.1 - 5.1e-12 46.0 0.2 1.3e-11 44.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK62816.1 - 3.4e-09 36.9 0.0 7.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK62816.1 - 3.8e-06 27.0 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK62816.1 - 1.4e-05 25.3 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK62816.1 - 5.2e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK62816.1 - 0.0098 16.2 0.0 0.097 13.0 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KIK62816.1 - 0.031 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein F-box-like PF12937.7 KIK62817.1 - 5e-06 26.3 0.0 0.00015 21.6 0.0 3.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK62817.1 - 1.9e-05 24.4 0.1 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.18 KIK62818.1 - 0.0044 17.1 8.0 0.0087 16.2 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4381 PF14316.6 KIK62819.1 - 0.00018 21.8 0.9 0.00029 21.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 KIK62819.1 - 0.0069 15.2 0.3 0.011 14.5 0.3 1.4 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK62819.1 - 0.0085 16.9 0.8 0.013 16.4 0.8 1.5 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 KIK62819.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MHYT PF03707.16 KIK62819.1 - 0.035 14.3 0.2 0.059 13.5 0.2 1.3 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Stevor PF17410.2 KIK62819.1 - 0.047 13.2 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4834 PF16118.5 KIK62819.1 - 0.11 13.5 0.1 0.2 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5305 PF17231.2 KIK62819.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OATP PF03137.20 KIK62819.1 - 0.16 10.2 0.0 0.17 10.1 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CD34_antigen PF06365.12 KIK62819.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 KIK62819.1 - 2.2 8.2 6.4 0.49 10.3 0.2 2.1 1 1 1 2 2 2 0 TMEM154 protein family OppC_N PF12911.7 KIK62819.1 - 8.9 6.4 6.3 0.91 9.5 0.5 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C FAA_hydrolase PF01557.18 KIK62820.1 - 4.1e-58 196.6 0.0 4.7e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KIK62820.1 - 0.00025 20.8 1.8 0.0029 17.4 0.2 2.3 1 1 1 2 2 2 1 KH domain Nucleo_P87 PF07267.11 KIK62822.1 - 0.053 12.4 4.8 0.06 12.2 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.32 KIK62829.1 - 3.2e-167 537.3 48.7 1.5e-12 47.8 0.1 15.8 15 0 0 15 15 15 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62829.1 - 4.9e-39 132.5 18.3 0.0081 16.4 0.1 14.5 1 1 14 15 15 15 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK62829.1 - 5.3e-26 91.7 6.8 0.00026 21.0 0.0 6.9 2 2 5 7 7 7 6 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK62829.1 - 1.5e-13 50.7 1.8 0.14 11.4 0.0 9.1 8 4 1 9 9 9 2 WD40-like domain Nup160 PF11715.8 KIK62829.1 - 2.6e-13 49.5 33.0 0.024 13.3 0.4 12.8 5 5 10 15 15 15 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK62829.1 - 4e-12 45.7 19.4 3.8 6.4 0.0 12.5 2 1 12 15 15 15 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK62829.1 - 1.3e-08 34.6 3.1 29 4.8 0.0 10.9 13 0 0 13 13 12 0 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK62829.1 - 7.7e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain nos_propeller PF18764.1 KIK62829.1 - 3.4e-06 26.9 19.7 47 4.0 0.0 11.6 13 0 0 13 13 13 0 Nitrous oxide reductase propeller repeat SdiA-regulated PF06977.11 KIK62829.1 - 3.9e-06 26.3 0.0 3.8 6.7 0.0 5.4 3 3 3 6 6 6 2 SdiA-regulated AAA_16 PF13191.6 KIK62829.1 - 0.00023 21.6 0.0 0.00058 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KIK62829.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase DsbC_N PF10411.9 KIK62829.1 - 0.0034 16.8 7.8 92 2.6 0.0 8.5 11 0 0 11 11 11 0 Disulfide bond isomerase protein N-terminus Cuticle_4 PF15955.5 KIK62829.1 - 0.026 15.2 2.6 3e+02 2.2 0.0 7.5 11 0 0 11 11 10 0 Cuticle protein AAA_22 PF13401.6 KIK62829.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK62829.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KIK62829.1 - 0.12 12.9 0.0 0.55 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4596 PF15363.6 KIK62829.1 - 5.9 7.2 30.8 1.6 9.0 0.1 8.8 10 0 0 10 10 10 0 Domain of unknown function (DUF4596) F-box PF00646.33 KIK62830.1 - 0.0075 16.1 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK62830.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KIK62830.1 - 0.026 14.4 0.3 0.061 13.2 0.3 1.7 1 0 0 1 1 1 0 F-box-like Not3 PF04065.15 KIK62831.1 - 2.2e-71 240.0 18.8 3.3e-71 239.4 18.8 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Plasmid_RAQPRD PF09686.10 KIK62831.1 - 0.65 10.3 3.2 2.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PulA_N1 PF17999.1 KIK62831.1 - 2.1 9.1 0.0 2.1 9.1 0.0 3.0 3 0 0 3 3 3 0 Pullulanase N1-terminal domain CE2_N PF17996.1 KIK62832.1 - 0.00049 20.0 0.1 0.073 13.1 0.0 3.0 3 1 0 3 3 3 1 Carbohydrate esterase 2 N-terminal EphA2_TM PF14575.6 KIK62832.1 - 0.096 13.6 0.1 0.16 12.9 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KIK62832.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 KIK62832.1 - 0.22 10.3 0.2 0.31 9.8 0.2 1.1 1 0 0 1 1 1 0 Amnionless GPI-anchored PF10342.9 KIK62834.1 - 2.1e-07 31.6 0.2 2.9e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DAHP_synth_2 PF01474.16 KIK62835.1 - 1.8e-200 666.0 0.0 2.1e-200 665.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DAHP_synth_2 PF01474.16 KIK62837.1 - 4.3e-136 453.9 0.0 5.1e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Pam17 PF08566.10 KIK62838.1 - 8.6e-59 198.1 0.0 1.6e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 CE2_N PF17996.1 KIK62839.1 - 0.00013 22.0 0.2 0.0026 17.8 0.1 2.9 3 1 0 3 3 3 1 Carbohydrate esterase 2 N-terminal Chromate_transp PF02417.15 KIK62839.1 - 0.0029 17.8 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Chromate transporter Mid2 PF04478.12 KIK62839.1 - 0.003 17.4 0.3 0.0056 16.5 0.0 1.6 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF2207 PF09972.9 KIK62839.1 - 0.069 11.9 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rick_17kDa_Anti PF05433.15 KIK62839.1 - 0.075 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain MgtE PF01769.16 KIK62839.1 - 0.11 12.9 1.4 0.48 10.8 0.1 2.2 2 0 0 2 2 2 0 Divalent cation transporter Amnionless PF14828.6 KIK62839.1 - 0.17 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 KIK62839.1 - 0.24 11.3 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Rifin CE2_N PF17996.1 KIK62840.1 - 0.00037 20.5 0.2 0.0046 16.9 0.0 2.5 2 1 0 2 2 2 1 Carbohydrate esterase 2 N-terminal stn_TNFRSF12A PF12191.8 KIK62840.1 - 0.0019 18.4 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Amnionless PF14828.6 KIK62840.1 - 0.017 14.0 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KIK62840.1 - 0.044 13.2 1.2 0.095 12.1 1.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF347 PF03988.12 KIK62840.1 - 0.067 13.4 0.4 0.16 12.2 0.4 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Mid2 PF04478.12 KIK62840.1 - 0.084 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KIK62840.1 - 0.088 12.7 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KIK62840.1 - 0.21 12.5 0.6 0.41 11.6 0.6 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.12 KIK62841.1 - 0.021 15.0 0.9 0.036 14.3 0.3 1.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Rax2 PF12768.7 KIK62841.1 - 0.033 13.7 0.1 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PlyB_C PF18684.1 KIK62841.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Pleurotolysin B C-terminal domain GPI-anchored PF10342.9 KIK62842.1 - 2.3e-08 34.7 0.9 3.5e-08 34.1 0.9 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIK62842.1 - 0.089 12.6 0.7 0.15 11.8 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KIK62843.1 - 1.3e-07 32.3 0.1 2.1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIK62843.1 - 0.031 14.1 1.1 0.052 13.3 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) CDC45 PF02724.14 KIK62843.1 - 0.11 10.7 14.5 0.13 10.6 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KIK62843.1 - 1.1 7.9 5.2 1.1 8.0 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 KIK62843.1 - 9.6 5.9 12.4 14 5.5 12.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein WD40 PF00400.32 KIK62844.1 - 5.6e-29 99.8 19.6 0.00056 20.7 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIK62844.1 - 1.3e-15 57.0 1.0 2.4e-15 56.2 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK62844.1 - 8.7e-10 38.2 0.2 1.8e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KIK62844.1 - 2.7e-06 27.6 0.0 0.78 10.1 0.0 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK62844.1 - 2.3e-05 23.3 0.3 0.013 14.2 0.0 2.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 CDC4_D PF16856.5 KIK62844.1 - 0.0059 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain WD40_like PF17005.5 KIK62844.1 - 0.022 14.1 0.0 0.074 12.4 0.0 1.7 2 1 0 2 2 2 0 WD40-like domain Serglycin PF04360.12 KIK62844.1 - 0.18 11.7 1.2 0.77 9.7 1.2 2.1 1 0 0 1 1 1 0 Serglycin Gcn1_N PF12074.8 KIK62847.1 - 4.7e-68 230.1 0.0 3.6e-67 227.2 0.0 2.7 1 1 0 1 1 1 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KIK62847.1 - 3.2e-33 110.9 17.1 0.14 12.5 0.1 18.9 20 0 0 20 20 18 8 HEAT repeat HEAT_EZ PF13513.6 KIK62847.1 - 2.7e-28 98.0 23.4 0.00077 19.9 0.0 17.2 14 4 6 20 20 18 6 HEAT-like repeat HEAT_2 PF13646.6 KIK62847.1 - 7.3e-24 84.0 32.4 0.00021 21.6 0.1 13.5 9 2 5 15 15 14 6 HEAT repeats Cnd1 PF12717.7 KIK62847.1 - 1.9e-10 41.0 0.0 0.75 9.8 0.0 8.9 7 2 4 11 11 11 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KIK62847.1 - 6.2e-10 39.0 0.0 0.001 18.7 0.0 5.8 4 2 1 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 KIK62847.1 - 4.5e-06 25.5 0.2 0.34 9.4 0.0 5.8 6 1 1 7 7 7 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KIK62847.1 - 1.2e-05 25.8 0.0 3.1 8.5 0.0 5.6 4 1 1 5 5 4 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KIK62847.1 - 0.00016 20.9 2.9 18 4.3 0.0 7.2 7 2 1 8 8 8 0 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KIK62847.1 - 0.00079 19.6 0.9 35 4.6 0.0 6.4 9 0 0 9 9 5 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KIK62847.1 - 0.0014 18.6 1.2 0.13 12.2 0.0 4.6 6 0 0 6 6 5 1 Myosin-binding striated muscle assembly central DUF3437 PF11919.8 KIK62847.1 - 0.0017 18.2 0.7 2.9 7.8 0.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Cohesin_HEAT PF12765.7 KIK62847.1 - 0.0028 17.9 5.1 6.1 7.2 0.0 5.3 5 0 0 5 5 4 1 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.6 KIK62847.1 - 0.0072 16.7 1.2 0.056 13.8 0.1 3.0 3 0 0 3 3 3 1 FANCI solenoid 2 IFRD PF05004.13 KIK62847.1 - 0.0077 15.4 14.6 1.6 7.8 0.0 7.5 8 2 0 9 9 9 2 Interferon-related developmental regulator (IFRD) NUC173 PF08161.12 KIK62847.1 - 0.026 14.2 0.7 1.4 8.5 0.0 4.3 5 1 0 5 5 4 0 NUC173 domain DUF3730 PF12530.8 KIK62847.1 - 0.029 13.9 0.2 0.65 9.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) DRIM PF07539.12 KIK62847.1 - 0.033 12.5 4.0 19 3.4 0.1 5.9 6 1 1 7 7 7 0 Down-regulated in metastasis DUF4042 PF13251.6 KIK62847.1 - 0.18 11.5 0.5 29 4.3 0.0 4.4 4 2 0 4 4 2 0 Domain of unknown function (DUF4042) DUF2267 PF10025.9 KIK62847.1 - 0.29 11.4 4.0 12 6.2 3.2 4.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) RabGAP-TBC PF00566.18 KIK62848.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TMA7 PF09072.10 KIK62849.1 - 0.039 14.8 0.5 0.06 14.2 0.5 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 Sec34 PF04136.15 KIK62849.1 - 0.09 12.7 2.2 0.15 11.9 2.2 1.4 1 1 0 1 1 1 0 Sec34-like family HDV_ag PF01517.18 KIK62849.1 - 0.15 11.9 0.4 0.19 11.5 0.4 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen XhlA PF10779.9 KIK62849.1 - 0.3 11.3 2.7 5.9 7.2 2.2 2.5 2 1 0 2 2 2 0 Haemolysin XhlA PA-IIL PF07472.11 KIK62850.1 - 0.002 18.4 0.0 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 Fucose-binding lectin II (PA-IIL) RepB PF07506.11 KIK62851.1 - 0.037 14.1 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein Tcp10_C PF07202.13 KIK62852.1 - 0.0083 16.1 0.0 0.023 14.7 0.0 1.6 2 0 0 2 2 2 1 T-complex protein 10 C-terminus DUF4184 PF13803.6 KIK62854.1 - 0.021 14.6 3.5 0.024 14.3 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) Pox_vIL-18BP PF05566.12 KIK62854.1 - 0.084 13.1 0.6 0.18 12.0 0.6 1.6 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein PA-IIL PF07472.11 KIK62857.1 - 0.0041 17.4 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Fucose-binding lectin II (PA-IIL) PA-IIL PF07472.11 KIK62858.1 - 0.017 15.4 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) Mit_ribos_Mrp51 PF11709.8 KIK62861.1 - 3.3e-12 46.7 1.8 1.4e-11 44.6 1.7 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit XPG_I PF00867.18 KIK62862.1 - 1.3e-12 47.9 0.0 1.7e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 XPG I-region SAP PF02037.27 KIK62865.1 - 5.6e-08 32.4 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF1819 PF08849.11 KIK62867.1 - 0.014 15.2 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF167 PF02594.16 KIK62868.1 - 0.011 15.8 0.1 0.029 14.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 GN3L_Grn1 PF08701.11 KIK62869.1 - 0.18 11.9 0.1 0.22 11.7 0.1 1.1 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase FHIPEP PF00771.20 KIK62870.1 - 0.00077 18.1 0.4 0.00082 18.0 0.4 1.0 1 0 0 1 1 1 1 FHIPEP family DivIVA PF05103.13 KIK62870.1 - 0.016 15.3 0.7 0.21 11.7 0.1 2.0 1 1 1 2 2 2 0 DivIVA protein Prefoldin PF02996.17 KIK62870.1 - 0.02 14.8 2.7 0.17 11.8 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit CCDC92 PF14916.6 KIK62870.1 - 0.098 12.4 0.1 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Peptidase_M41 PF01434.18 KIK62870.1 - 0.13 12.1 1.1 0.17 11.7 0.4 1.5 2 0 0 2 2 2 0 Peptidase family M41 DUF2205 PF10224.9 KIK62870.1 - 0.25 11.4 2.8 6.4 6.8 0.1 2.5 3 0 0 3 3 3 0 Short coiled-coil protein DMPK_coil PF08826.10 KIK62870.1 - 0.59 10.3 4.6 9.5 6.4 0.5 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Vta1_C PF18097.1 KIK62871.1 - 0.035 13.8 0.3 0.29 10.8 0.0 2.4 2 1 1 3 3 3 0 Vta1 C-terminal domain CENP-Q PF13094.6 KIK62871.1 - 0.061 13.5 0.3 0.069 13.3 0.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DDE_Tnp_IS1595 PF12762.7 KIK62874.1 - 0.13 12.3 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 ISXO2-like transposase domain Lyase_aromatic PF00221.19 KIK62875.1 - 0.0098 14.6 1.2 0.011 14.4 1.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase ARD PF03079.14 KIK62876.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 ARD/ARD' family Glutaredoxin2_C PF04399.13 KIK62878.1 - 0.064 13.1 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Baculo_PEP_C PF04513.12 KIK62879.1 - 0.031 14.3 13.2 0.095 12.7 13.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EI24 PF07264.11 KIK62879.1 - 0.12 12.6 8.9 0.16 12.2 8.9 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Collagen_mid PF15984.5 KIK62879.1 - 0.24 11.1 14.7 0.74 9.5 14.0 2.0 1 1 0 1 1 1 0 Bacterial collagen, middle region DUF2545 PF10810.8 KIK62879.1 - 1.6 9.0 11.8 5.7 7.2 10.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2545) Glutaredoxin2_C PF04399.13 KIK62883.1 - 0.097 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain NolB PF17398.2 KIK62884.1 - 0.032 14.6 1.4 0.044 14.2 1.4 1.3 1 0 0 1 1 1 0 Nodulation protein NolB Baculo_PEP_C PF04513.12 KIK62885.1 - 0.037 14.1 10.8 0.37 10.8 10.6 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF726 PF05277.12 KIK62885.1 - 0.11 11.4 6.7 1.5 7.7 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF726) DUF2545 PF10810.8 KIK62885.1 - 0.39 10.9 8.8 4.7 7.4 6.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2545) Baculo_PEP_C PF04513.12 KIK62886.1 - 0.067 13.2 12.3 0.21 11.6 12.2 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 KIK62887.1 - 2.2e-39 132.7 35.4 2.3e-06 28.2 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK62887.1 - 3.9e-07 30.3 0.0 0.51 10.7 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KIK62887.1 - 7.4e-07 29.0 0.1 1.7e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like Sporozoite_P67 PF05642.11 KIK62887.1 - 3.3e-05 22.2 13.8 3.3e-05 22.2 13.8 3.5 2 1 1 4 4 4 1 Sporozoite P67 surface antigen F-box PF00646.33 KIK62887.1 - 0.001 18.9 0.2 0.001 18.9 0.2 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KIK62887.1 - 0.0022 16.7 6.2 9.7 4.7 0.1 5.5 5 1 1 6 6 6 2 Nucleoporin Nup120/160 Hamartin PF04388.12 KIK62887.1 - 9.9 4.7 13.7 20 3.7 13.7 1.4 1 0 0 1 1 1 0 Hamartin protein Arrestin_N PF00339.29 KIK62889.1 - 1.3e-07 31.8 0.0 1.9e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIK62889.1 - 0.048 14.1 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Tyr_Deacylase PF02580.16 KIK62890.1 - 2.1e-55 187.2 0.0 2.3e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 KIK62891.1 - 6.4e-53 179.3 0.0 7e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans PF04082.18 KIK62893.1 - 4.2e-17 62.1 0.4 7.6e-17 61.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK62893.1 - 1.9e-05 24.7 7.5 3.9e-05 23.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIK62894.1 - 5.5e-09 35.8 1.5 2.7e-07 30.4 0.1 3.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIK62894.1 - 0.00044 20.1 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 F-box F-box PF00646.33 KIK62894.1 - 0.48 10.4 5.3 0.49 10.3 0.1 3.3 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 KIK62894.1 - 6.2 7.4 9.4 27 5.4 1.5 5.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK62895.1 - 2.7e-08 33.6 1.7 1e-07 31.7 0.1 2.9 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 KIK62895.1 - 0.024 14.4 1.8 0.18 11.6 1.8 2.6 1 0 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 KIK62895.1 - 0.12 12.8 15.3 0.58 10.7 0.6 5.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK62896.1 - 2.8e-06 27.1 0.0 1.2e-05 25.1 0.0 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK62896.1 - 0.04 14.3 15.1 0.66 10.5 1.0 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Radical_SAM_C PF16199.5 KIK62897.1 - 1e-29 102.3 0.0 2.1e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KIK62897.1 - 4.7e-17 62.9 0.1 1.8e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KIK62897.1 - 3.7e-10 40.1 0.1 7.6e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK62897.1 - 1.1e-06 28.6 0.1 2.5e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK62897.1 - 0.00032 21.1 0.2 0.0021 18.5 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK62897.1 - 0.043 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PAN_3 PF08277.12 KIK62898.1 - 7.8 6.4 6.2 0.85 9.5 0.4 2.4 3 0 0 3 3 3 0 PAN-like domain MMM1 PF10296.9 KIK62899.1 - 4.4e-11 42.4 0.0 4.4e-06 26.0 0.0 3.0 3 0 0 3 3 3 3 Maintenance of mitochondrial morphology protein 1 Hva1_TUDOR PF11160.8 KIK62900.1 - 5e-19 68.2 3.6 6e-19 68.0 3.6 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain DUF1918 PF08940.11 KIK62900.1 - 0.053 13.1 0.6 2.9 7.6 0.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1918) DUF237 PF03072.14 KIK62903.1 - 0.055 13.5 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF237) Retrotrans_gag PF03732.17 KIK62906.1 - 4.3e-07 30.1 0.1 1e-06 28.9 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK62906.1 - 0.00011 22.1 3.8 0.00019 21.4 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 KIK62906.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) UPF0242 PF06785.11 KIK62907.1 - 0.16 12.1 4.0 0.27 11.3 4.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 KIK62907.1 - 0.38 10.4 4.1 2.1 8.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fez1 PF06818.15 KIK62908.1 - 0.00046 20.7 5.3 0.00054 20.5 5.3 1.0 1 0 0 1 1 1 1 Fez1 Csm1_N PF18504.1 KIK62908.1 - 0.00054 20.2 8.0 0.019 15.3 3.3 2.9 1 1 2 3 3 3 1 Csm1 N-terminal domain HMMR_N PF15905.5 KIK62908.1 - 0.0011 18.5 3.3 0.0014 18.2 3.3 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Peptidase_S49_N PF08496.10 KIK62908.1 - 0.0074 16.4 1.9 0.0079 16.3 0.1 1.8 1 1 1 2 2 2 1 Peptidase family S49 N-terminal Spc42p PF11544.8 KIK62908.1 - 0.0075 16.2 4.7 1.1 9.3 2.6 3.0 1 1 1 2 2 2 1 Spindle pole body component Spc42p PKcGMP_CC PF16808.5 KIK62908.1 - 0.0085 15.9 13.7 0.2 11.5 1.6 3.6 3 1 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KIK62908.1 - 0.0089 14.9 6.3 0.012 14.5 6.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KIK62908.1 - 0.0093 15.9 10.1 0.079 13.0 6.7 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 KIK62908.1 - 0.016 15.0 6.0 0.032 14.1 1.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 KASH_CCD PF14662.6 KIK62908.1 - 0.02 14.8 7.9 0.03 14.2 7.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 KIK62908.1 - 0.024 13.7 3.5 0.026 13.6 3.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1635 PF07795.11 KIK62908.1 - 0.027 14.4 0.3 0.027 14.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) AAA_13 PF13166.6 KIK62908.1 - 0.04 12.6 0.7 0.045 12.4 0.7 1.0 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KIK62908.1 - 0.052 13.0 4.8 0.068 12.6 4.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 KIK62908.1 - 0.061 13.8 9.2 0.078 13.5 9.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Lebercilin PF15619.6 KIK62908.1 - 0.074 12.7 10.1 0.12 12.0 10.1 1.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 KIK62908.1 - 0.096 12.4 9.0 1.5 8.5 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 KIK62908.1 - 0.096 13.0 8.0 0.29 11.4 5.3 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF2460 PF09343.10 KIK62908.1 - 0.12 11.9 0.6 0.2 11.1 0.6 1.3 1 1 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) FAM76 PF16046.5 KIK62908.1 - 0.12 11.7 6.3 0.33 10.3 5.8 1.7 1 1 1 2 2 2 0 FAM76 protein PEP-utilisers_N PF05524.13 KIK62908.1 - 0.13 12.5 5.6 0.45 10.7 5.6 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 KIK62908.1 - 0.21 12.3 4.1 0.18 12.5 1.8 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Syntaphilin PF15290.6 KIK62908.1 - 0.27 10.9 7.7 0.39 10.3 7.5 1.4 1 1 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp CC2-LZ PF16516.5 KIK62908.1 - 0.4 11.1 7.8 2 8.9 3.7 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HBS1_N PF08938.10 KIK62908.1 - 0.46 10.8 3.6 3.3 8.1 3.6 2.2 1 1 0 1 1 1 0 HBS1 N-terminus Dzip-like_N PF13815.6 KIK62908.1 - 0.89 9.5 4.4 0.43 10.6 1.8 1.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ATG16 PF08614.11 KIK62908.1 - 2.5 8.3 13.6 0.5 10.6 7.8 1.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Rho_Binding PF08912.11 KIK62908.1 - 3 8.7 8.8 1 10.2 3.6 2.1 1 1 0 2 2 2 0 Rho Binding ZapB PF06005.12 KIK62908.1 - 8.4 6.9 14.2 6 7.4 9.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 KIK62908.1 - 9.1 6.3 9.1 16 5.6 9.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KDZ PF18758.1 KIK62910.1 - 6e-13 48.9 0.0 7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK62911.1 - 1.1e-12 48.1 0.0 1.3e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Cauli_VI PF01693.16 KIK62914.1 - 2.7e-05 24.4 0.0 5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin FdhE PF04216.12 KIK62914.1 - 0.012 15.5 3.6 0.016 15.1 3.6 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Mu-like_Pro PF10123.9 KIK62914.1 - 0.065 12.8 1.3 0.08 12.5 1.3 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein SpoVAE PF14097.6 KIK62914.1 - 0.098 12.3 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Cauli_VI PF01693.16 KIK62916.1 - 0.00074 19.8 0.1 0.0019 18.4 0.1 1.8 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyco_tran_28_C PF04101.16 KIK62917.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain bZIP_1 PF00170.21 KIK62918.1 - 1.9e-05 24.7 10.9 9.4e-05 22.4 5.9 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KIK62918.1 - 0.00028 20.9 6.7 0.00028 20.9 6.7 2.2 1 1 1 2 2 2 1 Basic region leucine zipper CENP-H PF05837.12 KIK62918.1 - 0.0068 16.8 3.1 0.012 16.0 3.1 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) bZIP_Maf PF03131.17 KIK62918.1 - 0.074 13.6 5.0 0.15 12.6 5.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor XhlA PF10779.9 KIK62918.1 - 0.14 12.3 1.9 1.2 9.4 1.2 2.2 1 1 1 2 2 2 0 Haemolysin XhlA bZIP_2 PF07716.15 KIK62920.1 - 1.4e-06 28.2 12.7 3.2e-06 27.1 11.2 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK62920.1 - 3.4e-05 23.8 12.6 0.00044 20.3 12.6 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIK62920.1 - 0.019 15.5 7.2 0.052 14.1 7.2 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor CENP-H PF05837.12 KIK62920.1 - 0.028 14.8 6.7 0.067 13.6 6.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ax_dynein_light PF10211.9 KIK62920.1 - 0.075 13.0 7.5 0.14 12.1 7.5 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain SKA2 PF16740.5 KIK62920.1 - 0.1 12.4 2.3 0.21 11.4 2.3 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TMPIT PF07851.13 KIK62920.1 - 0.23 10.7 3.0 0.36 10.0 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein PspB PF06667.12 KIK62920.1 - 0.33 11.0 4.4 0.8 9.8 0.4 2.4 1 1 1 2 2 2 0 Phage shock protein B FlaC_arch PF05377.11 KIK62920.1 - 0.41 11.1 2.8 1.6 9.2 2.8 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KIK62920.1 - 1.3 8.8 6.1 4.1 7.2 3.1 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF444 PF04285.12 KIK62920.1 - 3 6.8 7.7 2.6 7.0 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF444) XhlA PF10779.9 KIK62920.1 - 3.3 8.0 5.5 1.7 8.9 1.9 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Uso1_p115_C PF04871.13 KIK62920.1 - 5.5 7.4 14.4 0.58 10.5 4.8 2.8 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_9 PF13371.6 KIK62921.1 - 1.5e-06 28.3 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 KIK62921.1 - 0.0081 16.6 6.1 0.0081 16.6 6.1 2.1 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger TPR_14 PF13428.6 KIK62921.1 - 0.068 14.0 0.0 3.3 8.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK62921.1 - 0.069 13.0 0.0 3.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK62921.1 - 0.11 12.7 0.8 0.38 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK62921.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CCCH_3 PF15663.5 KIK62921.1 - 0.68 10.2 4.6 2 8.6 4.6 1.7 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 KIK62921.1 - 2.4 8.2 11.0 0.57 10.2 6.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK62921.1 - 2.8 7.9 15.2 0.82 9.5 7.2 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger TPR_9 PF13371.6 KIK62922.1 - 0.00056 20.0 0.1 0.0012 19.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK62922.1 - 0.0026 17.8 1.9 0.0046 17.1 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK62922.1 - 0.12 12.3 2.6 6.7 6.7 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH_3 PF15663.5 KIK62922.1 - 0.84 9.9 3.7 5.1 7.4 3.7 2.1 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KIK62922.1 - 1.4 9.5 11.0 3.5 8.2 1.3 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KIK62922.1 - 3.3 7.7 6.2 6.5 6.8 0.4 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK62922.1 - 3.8 7.7 4.9 24 5.1 0.6 2.8 2 1 0 2 2 2 0 Zinc finger domain AhpC-TSA_2 PF13911.6 KIK62923.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme bZIP_1 PF00170.21 KIK62924.1 - 1.6e-05 24.9 7.6 2.8e-05 24.1 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK62924.1 - 0.00029 20.8 8.6 0.00052 20.0 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Pro_racemase PF05544.11 KIK62925.1 - 3.3e-58 197.3 0.0 3.6e-57 193.9 0.0 2.1 1 1 0 1 1 1 1 Proline racemase HicA_toxin PF07927.12 KIK62926.1 - 4.1e-07 29.9 0.0 8.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fungal_trans PF04082.18 KIK62927.1 - 0.018 14.1 0.0 0.048 12.7 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK62927.1 - 0.14 12.3 5.7 0.26 11.4 5.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DHOase PF12890.7 KIK62930.1 - 0.17 11.8 0.8 0.38 10.7 0.3 1.7 2 0 0 2 2 2 0 Dihydro-orotase-like DUF4174 PF13778.6 KIK62930.1 - 0.23 11.9 1.8 0.73 10.3 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Mito_carr PF00153.27 KIK62931.1 - 3.5e-14 52.5 0.1 5.5e-07 29.4 0.1 3.3 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF2196 PF09962.9 KIK62932.1 - 5.4e-22 77.5 4.4 7.9e-22 77.0 4.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Ham1p_like PF01725.16 KIK62933.1 - 2.9e-57 193.6 0.0 3.3e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family BTB PF00651.31 KIK62935.1 - 0.0002 21.6 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KIK62936.1 - 2e-31 109.2 29.8 3.2e-31 108.5 29.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KIK62937.1 - 2.5e-19 70.3 0.8 3.4e-19 69.8 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK62937.1 - 3.7e-14 52.7 1.4 9.3e-14 51.4 0.2 2.3 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KIK62937.1 - 0.17 12.5 0.0 0.46 11.1 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TPR_2 PF07719.17 KIK62938.1 - 3.4e-07 29.9 0.6 0.00021 21.2 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK62938.1 - 9.4e-07 28.4 1.6 0.0008 19.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Geminin PF07412.12 KIK62938.1 - 0.0022 17.8 0.2 0.0038 17.0 0.2 1.4 1 0 0 1 1 1 1 Geminin TPR_8 PF13181.6 KIK62938.1 - 0.13 12.6 0.4 2.3 8.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SAPS PF04499.15 KIK62939.1 - 2.1e-109 366.5 0.0 2.7e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Defensin_propep PF00879.18 KIK62940.1 - 0.019 15.3 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Defensin propeptide CtaG_Cox11 PF04442.14 KIK62942.1 - 4.2e-55 185.9 0.0 1.9e-54 183.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Longin PF13774.6 KIK62942.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain ALO PF04030.14 KIK62943.1 - 1.3e-07 31.7 2.2 2.5e-07 30.8 2.2 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK62943.1 - 4.5e-07 29.7 0.1 1.1e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Chol_subst-bind PF09129.11 KIK62943.1 - 0.0051 15.8 5.2 0.015 14.2 1.1 2.7 2 1 0 2 2 2 1 Cholesterol oxidase, substrate-binding p450 PF00067.22 KIK62944.1 - 3.6e-77 260.1 0.0 6.9e-77 259.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Vac17 PF17321.2 KIK62944.1 - 0.033 13.6 0.2 0.046 13.2 0.2 1.1 1 0 0 1 1 1 0 Vacuole-related protein 17 Glyco_hydro_85 PF03644.13 KIK62945.1 - 2.4e-76 257.1 0.0 2.9e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 p450 PF00067.22 KIK62946.1 - 2.1e-28 99.3 0.0 4.1e-18 65.4 0.0 3.6 3 1 0 3 3 3 2 Cytochrome P450 GSHPx PF00255.19 KIK62948.1 - 1.8e-37 127.2 0.1 2.3e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KIK62948.1 - 6.7e-05 22.8 0.1 0.00029 20.7 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK62948.1 - 0.004 16.9 0.1 0.01 15.6 0.1 1.7 1 1 0 1 1 1 1 Redoxin Baculo_LEF-3 PF05847.11 KIK62948.1 - 0.07 12.3 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Phosphonate-bd PF12974.7 KIK62951.1 - 6.2e-05 22.7 0.0 8.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KIK62951.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.7 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 KIK62951.1 - 0.003 17.3 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 KIK62951.1 - 0.0044 16.5 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family LysR_substrate PF03466.20 KIK62951.1 - 0.21 10.9 0.0 3.8 6.8 0.0 2.0 2 0 0 2 2 2 0 LysR substrate binding domain ANAPC3 PF12895.7 KIK62952.1 - 7.4e-06 26.1 9.9 0.0014 18.8 1.9 2.8 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIK62952.1 - 0.00079 19.4 14.7 0.45 10.7 1.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK62952.1 - 0.0015 19.0 5.3 0.0031 18.0 0.8 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.20 KIK62952.1 - 0.0016 18.5 1.6 1.4 9.3 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_17 PF13431.6 KIK62952.1 - 0.0073 16.6 2.4 0.18 12.2 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK62952.1 - 0.018 15.3 4.7 1.9 8.9 0.0 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK62952.1 - 0.021 15.6 3.3 0.49 11.3 0.4 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KIK62952.1 - 0.082 13.3 4.4 0.13 12.7 4.2 1.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain PPR_2 PF13041.6 KIK62952.1 - 0.1 12.8 3.1 0.92 9.8 0.1 3.2 3 0 0 3 3 3 0 PPR repeat family TPR_6 PF13174.6 KIK62952.1 - 0.58 10.9 9.5 3.7 8.4 0.7 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK62952.1 - 3.7 8.0 8.6 1.5 9.2 1.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK62952.1 - 4.4 7.3 11.9 7.3 6.6 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Phage_tail_NK PF16532.5 KIK62954.1 - 0.052 13.2 0.2 0.095 12.3 0.2 1.4 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales ADH_zinc_N PF00107.26 KIK62956.1 - 3e-28 98.4 0.0 6.7e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK62956.1 - 9.4e-19 68.8 0.0 1.9e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK62956.1 - 6.1e-05 22.9 0.0 0.0002 21.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PA PF02225.22 KIK62956.1 - 0.0019 18.2 0.0 0.081 13.0 0.0 2.6 1 1 1 2 2 2 1 PA domain TrkA_N PF02254.18 KIK62956.1 - 0.06 13.6 0.3 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain TIMELESS PF04821.14 KIK62957.1 - 2.8e-79 266.3 1.4 2.8e-79 266.3 1.4 2.2 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KIK62957.1 - 9.2e-12 44.9 0.1 9.2e-12 44.9 0.1 3.7 2 1 1 4 4 4 1 Timeless protein C terminal region tRNA_lig_CPD PF08302.11 KIK62957.1 - 0.068 12.6 1.9 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain ADH_zinc_N PF00107.26 KIK62958.1 - 7.2e-29 100.4 0.1 1.6e-28 99.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK62958.1 - 5.1e-18 66.4 0.0 8.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK62958.1 - 4.1e-06 26.6 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIK62958.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain CMAS PF02353.20 KIK62958.1 - 0.071 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PA PF02225.22 KIK62958.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 PA domain Abhydrolase_3 PF07859.13 KIK62959.1 - 1.8e-18 67.2 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK62959.1 - 3e-07 30.2 0.0 0.0089 15.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KIK62959.1 - 0.00013 21.0 0.0 0.00026 20.0 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KIK62959.1 - 0.0024 17.7 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KIK62960.1 - 1.8e-17 63.9 0.0 6.4e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK62960.1 - 2e-09 37.3 0.0 0.00016 21.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIK62960.1 - 4.7e-06 26.6 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK62960.1 - 0.0087 15.0 0.0 0.017 14.0 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family p450 PF00067.22 KIK62961.1 - 3e-75 253.7 0.0 5.7e-75 252.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3140 PF11338.8 KIK62961.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DUF4793 PF16041.5 KIK62962.1 - 0.18 12.0 0.5 0.51 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) Sad1_UNC PF07738.13 KIK62963.1 - 3.3e-23 82.2 0.0 2.1e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal ABC_membrane PF00664.23 KIK62964.1 - 9.3e-48 163.2 35.0 2.7e-27 96.1 10.6 3.4 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK62964.1 - 2.2e-42 144.8 0.1 1.5e-26 93.5 0.0 3.2 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KIK62964.1 - 1.1e-09 38.1 4.3 0.015 14.7 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KIK62964.1 - 2e-05 24.8 1.8 0.018 15.1 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 KIK62964.1 - 0.00017 21.3 2.3 0.19 11.5 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK62964.1 - 0.00024 21.7 0.9 0.062 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KIK62964.1 - 0.00035 20.0 1.1 0.14 11.5 0.2 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 KIK62964.1 - 0.0004 20.8 0.1 1.7 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KIK62964.1 - 0.00099 18.2 0.0 0.59 9.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KIK62964.1 - 0.0012 18.4 0.4 1.8 8.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 KIK62964.1 - 0.0029 17.5 5.3 2.3 7.9 0.3 4.1 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIK62964.1 - 0.0037 17.3 1.1 0.27 11.3 0.1 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 KIK62964.1 - 0.004 16.1 1.6 0.42 9.5 0.2 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 KIK62964.1 - 0.0054 16.3 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 KIK62964.1 - 0.0076 15.1 0.7 0.26 10.0 0.1 2.8 2 1 0 2 2 2 1 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 KIK62964.1 - 0.0081 16.1 0.8 4.3 7.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Pox_A32 PF04665.12 KIK62964.1 - 0.027 13.9 4.5 2.3 7.6 0.3 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.6 KIK62964.1 - 0.032 14.5 0.7 14 5.9 0.3 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIK62964.1 - 0.047 13.4 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KIK62964.1 - 0.05 14.0 0.1 25 5.3 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KIK62964.1 - 0.065 13.3 1.6 9.8 6.2 0.4 2.6 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.14 KIK62964.1 - 0.091 12.8 0.6 22 5.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIK62964.1 - 0.094 12.4 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KIK62964.1 - 0.11 12.5 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Roc PF08477.13 KIK62964.1 - 0.12 12.6 0.2 25 5.1 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KIK62964.1 - 0.14 12.6 0.8 32 5.0 0.0 3.0 3 0 0 3 3 2 0 RNA helicase cobW PF02492.19 KIK62964.1 - 0.23 11.0 1.7 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIK62964.1 - 0.43 10.5 1.6 21 5.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Abhydrolase_1 PF00561.20 KIK62966.1 - 4.6e-07 29.7 0.0 3.1e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK62966.1 - 0.0015 17.9 0.1 0.0094 15.2 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK62967.1 - 1.9e-33 116.2 0.0 2.9e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK62967.1 - 6.4e-11 42.0 0.0 1.7e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK62967.1 - 1.4e-09 38.9 0.0 1.8e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIK62967.1 - 0.0088 15.5 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF4112 PF13430.6 KIK62968.1 - 3.3e-28 98.0 0.3 4.4e-28 97.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Cpn60_TCP1 PF00118.24 KIK62969.1 - 1.3e-155 518.8 2.0 1.5e-155 518.6 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 KIK62970.1 - 2e-36 126.4 0.6 2.7e-36 126.0 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK62970.1 - 0.00081 19.8 0.1 0.0017 18.8 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KIK62970.1 - 0.045 13.4 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Endomucin PF07010.12 KIK62972.1 - 0.21 11.5 10.8 0.35 10.8 10.8 1.4 1 0 0 1 1 1 0 Endomucin Osw5 PF17062.5 KIK62972.1 - 0.28 11.3 2.2 0.68 10.1 2.2 1.6 1 0 0 1 1 1 0 Outer spore wall 5 Abhydrolase_6 PF12697.7 KIK62973.1 - 4.6e-14 53.5 0.1 7.7e-14 52.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KIK62974.1 - 3.8e-14 53.8 0.2 6.1e-14 53.1 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family HD_3 PF13023.6 KIK62975.1 - 1.5e-40 138.9 0.9 1.7e-40 138.6 0.9 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KIK62975.1 - 6.9e-10 39.0 0.2 1e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KIK62975.1 - 0.0091 16.2 0.4 0.016 15.4 0.4 1.4 1 0 0 1 1 1 1 HD domain DUF4765 PF15962.5 KIK62975.1 - 0.22 9.4 0.1 0.27 9.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) CRAL_TRIO PF00650.20 KIK62976.1 - 2.1e-30 105.5 0.0 3.2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK62976.1 - 5.4e-16 58.5 0.6 5.4e-16 58.5 0.6 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIK62976.1 - 0.024 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain NARP1 PF12569.8 KIK62976.1 - 0.086 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.14 KIK62976.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase PI-PLC-X PF00388.19 KIK62977.1 - 5.7e-43 146.0 0.0 1e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIK62977.1 - 2e-28 99.0 0.0 3.6e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIK62977.1 - 3.2e-07 30.6 0.1 7.4e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain DPM3 PF08285.11 KIK62979.1 - 4.6e-32 110.1 0.1 5.1e-32 109.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SlyX PF04102.12 KIK62982.1 - 0.01 16.4 4.7 0.63 10.7 2.9 2.9 2 1 0 2 2 2 0 SlyX Tropomyosin PF00261.20 KIK62982.1 - 0.011 15.2 5.8 0.022 14.1 5.8 1.4 1 0 0 1 1 1 0 Tropomyosin Spc7 PF08317.11 KIK62982.1 - 0.038 12.9 1.6 0.062 12.2 1.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3618 PF12277.8 KIK62982.1 - 0.042 14.1 2.2 0.18 12.1 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Atg14 PF10186.9 KIK62982.1 - 0.043 12.9 1.5 0.081 12.0 1.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KIK62982.1 - 0.26 11.5 10.0 0.087 13.0 6.5 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DASH_Spc19 PF08287.11 KIK62982.1 - 0.9 9.4 8.8 0.69 9.8 5.1 2.2 1 1 1 2 2 2 0 Spc19 ADIP PF11559.8 KIK62982.1 - 1.3 9.1 6.8 3 7.9 6.7 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA PF00004.29 KIK62983.1 - 8.4e-42 142.7 0.0 1.5e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK62983.1 - 1.8e-10 40.6 0.0 3.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIK62983.1 - 1.5e-09 37.5 0.2 3e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIK62983.1 - 1.4e-05 25.3 0.0 3.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK62983.1 - 2.3e-05 24.7 0.2 0.03 14.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KIK62983.1 - 3.7e-05 23.0 0.0 6.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK62983.1 - 0.0002 21.8 0.3 0.009 16.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KIK62983.1 - 0.0004 20.4 0.2 0.0022 18.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK62983.1 - 0.00052 19.8 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 KIK62983.1 - 0.0057 16.3 0.2 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_3 PF07726.11 KIK62983.1 - 0.0064 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIK62983.1 - 0.0074 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KIK62983.1 - 0.013 14.8 0.2 0.27 10.6 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.6 KIK62983.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK62983.1 - 0.027 15.0 0.8 0.044 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KIK62983.1 - 0.035 13.9 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KIK62983.1 - 0.049 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KIK62983.1 - 0.062 13.5 0.3 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIK62983.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KIK62983.1 - 0.13 11.9 0.3 0.37 10.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK62983.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK62983.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Yip1 PF04893.17 KIK62984.1 - 6.1e-14 52.1 16.4 9e-14 51.6 16.4 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KIK62984.1 - 0.15 11.8 8.5 0.23 11.2 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Citrate_synt PF00285.21 KIK62985.1 - 7.8e-122 406.8 0.0 9.5e-122 406.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF4816 PF16086.5 KIK62985.1 - 0.11 12.5 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) TRI5 PF06330.11 KIK62989.1 - 8.6e-17 61.0 0.0 1.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF815 PF05673.13 KIK62989.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Tir_receptor_N PF07490.11 KIK62989.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Fae PF08714.11 KIK62989.1 - 0.094 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) TRI5 PF06330.11 KIK62990.1 - 1.7e-13 50.2 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) ATP_synt_H PF05493.13 KIK62991.1 - 1.3e-19 70.4 9.1 1.6e-19 70.1 9.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H CBP_BcsF PF11120.8 KIK62991.1 - 0.013 15.6 0.9 0.013 15.6 0.9 1.9 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsF DUF4131 PF13567.6 KIK62991.1 - 0.18 11.5 5.1 0.19 11.4 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Vps39_2 PF10367.9 KIK62992.1 - 3.3e-09 37.2 0.0 1e-08 35.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KIK62992.1 - 0.0074 16.6 0.5 0.036 14.4 0.5 2.2 1 1 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KIK62992.1 - 0.066 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Region in Clathrin and VPS RMI1_N PF08585.12 KIK62993.1 - 2.1e-30 106.1 0.0 2.8e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Herpes_UL56 PF04534.12 KIK62994.1 - 0.069 12.6 0.2 0.075 12.5 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL56 protein MIF4G PF02854.19 KIK62995.1 - 1e-28 100.5 1.1 1.6e-28 99.8 1.1 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KIK62995.1 - 3.7e-20 72.0 0.0 1.2e-19 70.3 0.0 2.0 1 0 0 1 1 1 1 MA3 domain Methyltransf_31 PF13847.6 KIK62996.1 - 5.6e-17 61.9 0.0 7.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK62996.1 - 9.1e-07 29.5 0.0 1.4e-05 25.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK62996.1 - 3.6e-06 27.7 0.0 9.4e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK62996.1 - 1.7e-05 24.7 0.0 3.4e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK62996.1 - 2.5e-05 23.9 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KIK62996.1 - 0.00065 20.3 0.0 0.0075 16.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIK62996.1 - 0.0065 16.5 0.0 0.0082 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIK62996.1 - 0.0098 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 KIK62996.1 - 0.024 13.5 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pkinase PF00069.25 KIK62997.1 - 2.6e-66 223.7 0.0 3.5e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK62997.1 - 8.8e-24 84.2 0.0 4.4e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK62997.1 - 1e-06 28.0 0.1 1.7e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK62997.1 - 0.00049 20.1 0.2 0.00067 19.6 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK62997.1 - 0.018 14.1 0.0 0.043 12.9 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 KIK62997.1 - 0.13 11.5 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like XPG_N PF00752.17 KIK62998.1 - 2.7e-29 101.6 0.0 5.6e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIK62998.1 - 8.9e-25 86.9 0.0 3e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 KIK62998.1 - 0.0015 18.0 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KIK62998.1 - 0.022 15.3 0.0 0.2 12.2 0.0 2.6 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DUF3285 PF11688.8 KIK62999.1 - 0.18 11.8 0.7 0.35 10.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Methyltransf_25 PF13649.6 KIK63000.1 - 9.9e-15 55.0 0.0 1.9e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK63000.1 - 8.1e-11 42.4 0.0 1.7e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK63000.1 - 5e-08 32.6 0.0 7.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIK63000.1 - 1.6e-07 31.3 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63000.1 - 1.9e-06 28.5 0.0 3.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK63000.1 - 2.6e-05 24.1 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK63000.1 - 0.00067 19.3 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KIK63000.1 - 0.001 18.6 0.0 0.0021 17.5 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KIK63000.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KIK63000.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Peptidase_M24 PF00557.24 KIK63001.1 - 4.3e-15 56.0 0.1 5.9e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pcc1 PF09341.10 KIK63002.1 - 1.1e-23 83.1 1.3 1.2e-23 83.0 1.3 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 XRN_M PF17846.1 KIK63002.1 - 0.027 13.4 0.1 0.03 13.3 0.1 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Pam16 PF03656.13 KIK63003.1 - 0.00059 19.8 0.0 0.00073 19.6 0.0 1.1 1 0 0 1 1 1 1 Pam16 Dyp_perox PF04261.12 KIK63003.1 - 0.00081 18.5 0.0 0.00091 18.3 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DnaJ PF00226.31 KIK63003.1 - 0.0009 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Fe-ADH PF00465.19 KIK63004.1 - 1.1e-72 244.8 1.6 1.3e-72 244.6 1.6 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIK63004.1 - 3.4e-12 46.6 0.6 5.3e-12 46.0 0.4 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Pec_lyase_C PF00544.19 KIK63005.1 - 1.2e-12 47.9 11.3 5.5e-11 42.5 11.3 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIK63005.1 - 4.4e-07 29.9 20.3 1.1e-05 25.4 11.0 2.4 1 1 1 2 2 2 2 Right handed beta helix region Lyase_catalyt PF09093.11 KIK63005.1 - 0.23 10.6 0.6 0.32 10.1 0.6 1.1 1 0 0 1 1 1 0 Lyase, catalytic Med25_VWA PF11265.8 KIK63006.1 - 0.0045 16.8 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Tektin PF03148.14 KIK63006.1 - 0.82 8.4 2.9 1.2 7.8 2.9 1.1 1 0 0 1 1 1 0 Tektin family Bud13 PF09736.9 KIK63012.1 - 1.2e-55 187.9 12.0 1.2e-55 187.9 12.0 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex SPT16 PF08644.11 KIK63012.1 - 0.87 9.8 3.6 1.7 8.9 3.6 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Glutaredoxin PF00462.24 KIK63013.1 - 4.4e-16 58.8 0.0 6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KIK63013.1 - 0.095 13.1 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KIK63013.1 - 0.11 13.0 0.3 0.28 11.7 0.3 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KIK63013.1 - 0.12 12.4 0.0 0.32 11.1 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin domain MFS_1 PF07690.16 KIK63015.1 - 3.7e-16 59.0 20.4 3.7e-16 59.0 20.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK63015.1 - 0.00017 20.6 1.2 0.00037 19.5 1.2 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MerE PF05052.12 KIK63015.1 - 0.014 15.3 0.4 0.045 13.7 0.4 1.8 1 0 0 1 1 1 0 MerE protein PDH PF02153.17 KIK63016.1 - 9.8e-13 47.7 0.0 1.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 KIK63016.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KIK63016.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIK63016.1 - 0.0034 17.9 0.1 0.012 16.2 0.1 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIK63016.1 - 0.0036 17.2 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIK63016.1 - 0.0043 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KIK63016.1 - 0.0055 16.8 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KIK63016.1 - 0.0077 16.4 0.0 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cellulase PF00150.18 KIK63017.1 - 1.7e-45 155.6 0.0 2.2e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK63017.1 - 6.6e-14 51.6 9.9 6.6e-14 51.6 9.9 3.5 4 0 0 4 4 4 1 Fungal cellulose binding domain SARAF PF06682.12 KIK63018.1 - 3.8e-60 204.3 0.6 4.6e-60 204.0 0.6 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis OPT PF03169.15 KIK63019.1 - 8.3e-120 401.3 23.6 9.6e-120 401.1 23.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BTB PF00651.31 KIK63020.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain tRNA-synt_1g PF09334.11 KIK63021.1 - 1.6e-129 432.1 0.0 2e-129 431.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KIK63021.1 - 1.8e-06 28.0 6.8 3.5e-06 27.1 6.8 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KIK63021.1 - 0.0089 14.3 0.0 0.24 9.6 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK63021.1 - 0.021 14.8 0.0 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA DUF1289 PF06945.13 KIK63021.1 - 0.16 11.8 2.6 1.8 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) zinc-ribbons_6 PF07191.12 KIK63021.1 - 0.62 10.1 5.6 1.5 8.8 5.6 1.7 1 0 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.9 KIK63021.1 - 0.71 10.0 3.2 0.47 10.6 0.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.7 KIK63021.1 - 1 9.4 6.5 2.8 8.0 6.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon DUF1793 PF08760.11 KIK63022.1 - 3.2e-32 112.3 1.2 3.3e-32 112.2 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) MFS_1 PF07690.16 KIK63023.1 - 1.8e-21 76.4 16.8 1.9e-17 63.2 13.0 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIK63023.1 - 1.5e-05 23.6 0.3 1.5e-05 23.6 0.3 2.0 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L31e PF01198.19 KIK63024.1 - 3.3e-35 120.2 0.1 4.7e-35 119.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e Rubrerythrin PF02915.17 KIK63027.1 - 0.0011 19.3 2.6 0.0011 19.3 2.6 1.8 2 0 0 2 2 2 1 Rubrerythrin MtrA PF04208.14 KIK63027.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A BAR_3 PF16746.5 KIK63027.1 - 0.17 11.5 2.6 0.29 10.8 2.6 1.3 1 0 0 1 1 1 0 BAR domain of APPL family HSP20 PF00011.21 KIK63029.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK63029.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA UvrD-helicase PF00580.21 KIK63032.1 - 2.6e-66 224.3 0.0 4.9e-66 223.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KIK63032.1 - 6.8e-57 193.4 0.0 6.6e-56 190.2 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIK63032.1 - 7e-34 117.3 0.1 1.6e-33 116.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK63032.1 - 2e-13 49.9 0.1 4.7e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIK63032.1 - 2.2e-08 34.1 1.2 0.068 12.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIK63032.1 - 1.9e-06 27.7 0.1 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KIK63032.1 - 0.00042 20.0 0.0 0.013 15.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KIK63032.1 - 0.00065 19.6 0.2 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKN1 PF03935.15 KIK63034.1 - 3.2e-185 616.3 9.5 3.8e-185 616.1 9.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sugar_tr PF00083.24 KIK63035.1 - 3e-119 398.8 24.8 3.8e-119 398.5 24.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63035.1 - 3.1e-25 88.9 75.6 2.5e-20 72.7 37.3 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Peptidase_C14 PF00656.22 KIK63037.1 - 1.9e-65 221.3 0.1 2.3e-65 221.0 0.1 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIK63037.1 - 0.12 12.4 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Metallophos PF00149.28 KIK63038.1 - 6.3e-12 46.4 0.2 1.1e-11 45.6 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK63038.1 - 5.8e-07 29.9 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KIK63038.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily PsbI PF02532.14 KIK63038.1 - 0.14 12.1 1.0 0.72 9.8 1.5 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) FBPase_2 PF06874.11 KIK63038.1 - 0.19 10.0 0.3 0.87 7.8 0.3 1.8 1 1 1 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Peroxin-3 PF04882.12 KIK63039.1 - 9.3e-102 341.4 1.2 1.1e-101 341.2 1.2 1.0 1 0 0 1 1 1 1 Peroxin-3 Herpes_U59 PF04529.12 KIK63039.1 - 0.011 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus U59 protein PAP1 PF08601.10 KIK63039.1 - 4.3 7.0 8.5 6.6 6.4 8.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4798 PF16055.5 KIK63039.1 - 6.4 7.1 6.2 0.3 11.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4798) GGACT PF06094.12 KIK63040.1 - 6.2e-13 49.4 0.0 9.2e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like CTU2 PF10288.9 KIK63041.1 - 1.2e-14 54.5 3.3 2.3e-14 53.6 0.7 2.6 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DZR PF12773.7 KIK63041.1 - 0.26 11.4 4.4 3 8.0 0.1 3.0 2 2 1 3 3 3 0 Double zinc ribbon Paired_CXXCH_1 PF09699.10 KIK63041.1 - 0.43 10.4 1.9 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-C3HC4_3 PF13920.6 KIK63041.1 - 5.4 7.0 10.8 0.65 9.9 1.2 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPRTase PF14681.6 KIK63042.1 - 1.5e-42 145.4 0.0 2.2e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KIK63042.1 - 4.3e-12 46.2 0.0 6.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Lipase_GDSL_2 PF13472.6 KIK63043.1 - 3.7e-10 40.5 0.4 4.9e-10 40.1 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK63043.1 - 0.0041 17.1 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UPF0731 PF14982.6 KIK63044.1 - 0.17 12.1 3.0 0.59 10.3 3.0 2.0 1 0 0 1 1 1 0 UPF0731 family Atrophin-1 PF03154.15 KIK63044.1 - 4.6 5.4 11.6 7.8 4.6 11.6 1.4 1 0 0 1 1 1 0 Atrophin-1 family COX5B PF01215.19 KIK63045.1 - 4.2e-40 136.4 0.0 4.5e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KIK63045.1 - 0.026 14.6 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger domain Na_Ca_ex PF01699.24 KIK63046.1 - 1.5e-22 80.2 33.4 5.9e-16 58.8 15.6 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF2627 PF11118.8 KIK63046.1 - 0.5 11.0 3.8 32 5.2 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) Ribosomal_S11 PF00411.19 KIK63047.1 - 2.9e-47 159.6 1.5 3.6e-47 159.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Cellulase PF00150.18 KIK63051.1 - 4.1e-11 42.8 0.2 4.1e-11 42.8 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF883 PF05957.13 KIK63052.1 - 8.1 7.1 13.5 19 6.0 2.5 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4585 PF15232.6 KIK63053.1 - 0.24 11.5 1.8 0.4 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) ADH_N_2 PF16884.5 KIK63054.1 - 3.9e-28 97.5 0.0 6.8e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIK63054.1 - 5.2e-18 65.3 0.0 7.8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK63054.1 - 3.8e-07 31.2 0.0 6.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KIK63054.1 - 0.049 13.3 0.4 0.079 12.7 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 KIK63054.1 - 0.065 12.7 0.4 0.13 11.7 0.4 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 KIK63054.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L1 PF00687.21 KIK63055.1 - 1.7e-46 158.5 2.3 2e-46 158.3 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Adeno_E3_CR2 PF02439.15 KIK63056.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KIK63056.1 - 0.13 13.1 0.0 0.23 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KIK63056.1 - 0.17 11.8 1.3 0.31 11.0 1.3 1.3 1 0 0 1 1 1 0 Syndecan domain Sugar_tr PF00083.24 KIK63057.1 - 2.6e-110 369.4 24.3 3.7e-110 368.9 24.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63057.1 - 1.6e-24 86.5 69.8 5.8e-19 68.2 34.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Prolactin_RP PF15172.6 KIK63058.1 - 0.12 12.1 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Prolactin-releasing peptide Alpha_kinase PF02816.18 KIK63059.1 - 1.8e-16 60.8 0.0 2.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Sugar_tr PF00083.24 KIK63060.1 - 3e-107 359.3 23.9 3.9e-107 358.9 23.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63060.1 - 2.1e-19 69.7 45.3 3.8e-13 49.1 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hc1 PF07432.13 KIK63062.1 - 0.21 12.0 0.0 0.34 11.3 0.0 1.2 1 0 0 1 1 1 0 Histone H1-like protein Hc1 LysE PF01810.18 KIK63064.1 - 0.22 11.0 0.1 0.31 10.5 0.1 1.2 1 0 0 1 1 1 0 LysE type translocator PIP5K PF01504.18 KIK63065.1 - 2e-46 158.4 0.0 2.4e-37 128.7 0.1 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase NAP PF00956.18 KIK63065.1 - 0.07 12.3 0.1 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) DnaJ PF00226.31 KIK63066.1 - 3.5e-20 71.9 0.9 8.9e-20 70.6 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain DDHD PF02862.17 KIK63066.1 - 0.024 14.8 0.8 0.038 14.1 0.8 1.4 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 KIK63066.1 - 7.2 5.0 13.6 11 4.4 13.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein U79_P34 PF03064.16 KIK63066.1 - 8.6 5.6 11.5 17 4.7 11.5 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 LsmAD PF06741.13 KIK63067.1 - 1.2e-28 99.5 1.3 2.7e-28 98.3 1.3 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 KIK63067.1 - 0.0081 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KIK63067.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain Mad3_BUB1_I PF08311.12 KIK63068.1 - 3.7e-35 120.6 0.6 6.3e-35 119.9 0.6 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KIK63068.1 - 1.7e-14 53.8 0.0 5.9e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63068.1 - 3.9e-07 29.6 0.0 6.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 KIK63068.1 - 2.9e-06 27.3 0.0 7.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Aldo_ket_red PF00248.21 KIK63070.1 - 1.1e-37 129.9 0.0 1.3e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DMA PF03474.14 KIK63070.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 DMRTA motif BRE1 PF08647.11 KIK63073.1 - 0.0085 16.1 54.6 0.013 15.5 15.2 4.6 4 0 0 4 4 4 2 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 KIK63073.1 - 7.3 6.6 59.6 0.55 10.3 2.9 4.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Alpha-amylase PF00128.24 KIK63074.1 - 8.8e-21 74.8 0.0 5.8e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KIK63074.1 - 8.7e-05 20.9 0.3 0.66 8.1 0.1 3.3 3 1 0 3 3 3 2 Glycosyl hydrolase family 70 Amidase PF01425.21 KIK63075.1 - 2.9e-66 224.3 0.0 4.5e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF155 PF02582.14 KIK63076.1 - 7.8e-48 162.9 0.0 1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Lactonase PF10282.9 KIK63077.1 - 4e-05 23.1 0.0 0.0035 16.6 0.0 2.8 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller PDZ_6 PF17820.1 KIK63077.1 - 0.12 12.2 0.5 22 5.0 0.1 2.6 2 0 0 2 2 2 0 PDZ domain WD40 PF00400.32 KIK63078.1 - 3.6e-35 119.4 19.3 1.1e-09 38.7 0.8 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK63078.1 - 4.2e-16 59.0 0.0 5.1e-06 26.7 0.0 5.9 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK63078.1 - 0.00029 19.9 0.3 0.35 9.8 0.0 3.1 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK63078.1 - 0.00046 19.6 0.0 3.9 6.7 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain WDCP PF15390.6 KIK63078.1 - 0.039 12.3 0.0 0.061 11.7 0.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Thioredoxin PF00085.20 KIK63079.1 - 4.4e-50 168.0 0.0 2.2e-24 85.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KIK63079.1 - 4.1e-23 82.1 0.9 7.7e-23 81.2 0.9 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KIK63079.1 - 2.8e-15 56.7 0.1 3e-08 34.1 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KIK63079.1 - 3.7e-15 56.1 0.0 4.4e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIK63079.1 - 1.6e-11 44.2 0.0 6.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KIK63079.1 - 1.8e-09 37.8 0.1 0.088 13.1 0.0 4.4 2 2 2 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 KIK63079.1 - 9.8e-07 28.6 0.1 0.046 13.4 0.0 2.5 2 1 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KIK63079.1 - 3.2e-06 27.1 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Glutaredoxin PF00462.24 KIK63079.1 - 1.6e-05 25.0 0.7 0.00052 20.2 0.0 3.2 3 1 0 3 3 3 1 Glutaredoxin TraF PF13728.6 KIK63079.1 - 3.7e-05 23.7 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KIK63079.1 - 0.026 14.7 1.8 7.3 6.7 0.1 3.2 3 2 1 4 4 4 0 Thioredoxin HyaE PF07449.11 KIK63079.1 - 0.032 14.2 0.0 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KIK63079.1 - 0.061 13.1 0.4 7.1 6.4 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin Exo_endo_phos PF03372.23 KIK63080.1 - 1.5e-10 41.0 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SLATT_fungal PF18142.1 KIK63082.1 - 5.4e-43 145.8 0.2 7.7e-43 145.3 0.2 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain CBFD_NFYB_HMF PF00808.23 KIK63083.1 - 3.3e-16 59.3 0.3 6.1e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK63083.1 - 2e-05 25.0 0.1 2e-05 25.0 0.1 2.7 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KIK63083.1 - 0.027 14.6 0.4 0.057 13.5 0.4 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CCDC53 PF10152.9 KIK63083.1 - 1.7 9.1 6.2 2.7 8.4 6.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RR_TM4-6 PF06459.12 KIK63083.1 - 3 7.6 10.3 4.2 7.1 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 KIK63083.1 - 4.1 6.6 9.0 5.4 6.3 9.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 KIK63083.1 - 4.2 6.3 5.0 5.4 5.9 5.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FRG2 PF15315.6 KIK63083.1 - 7.1 6.8 11.8 12 6.1 11.8 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Sugar_tr PF00083.24 KIK63084.1 - 8.5e-72 242.4 22.5 1e-71 242.2 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63084.1 - 5.4e-22 78.2 29.7 4.7e-20 71.8 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SART-1 PF03343.13 KIK63086.1 - 3e-166 554.6 67.8 6.3e-166 553.6 63.8 2.0 2 0 0 2 2 2 2 SART-1 family RNase_HII PF01351.18 KIK63087.1 - 3.7e-50 170.5 0.0 4.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII TPR_1 PF00515.28 KIK63088.1 - 3.7e-28 96.2 12.5 4.4e-05 23.1 4.2 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63088.1 - 3.5e-21 73.5 17.8 0.00061 19.7 0.1 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK63088.1 - 1.7e-19 68.3 13.7 0.00027 20.9 0.0 7.9 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KIK63088.1 - 3.8e-17 62.7 0.0 1e-16 61.2 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 KIK63088.1 - 4e-13 49.0 24.4 0.014 16.2 0.1 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK63088.1 - 1.3e-09 37.4 14.5 0.025 14.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK63088.1 - 1.6e-09 37.3 6.8 2.9e-06 26.8 1.0 4.4 3 2 2 5 5 5 3 TPR repeat TPR_12 PF13424.6 KIK63088.1 - 3.5e-09 36.8 28.1 0.0051 17.1 0.4 6.4 5 1 2 7 7 6 4 Tetratricopeptide repeat ChAPs PF09295.10 KIK63088.1 - 4.7e-08 32.4 1.1 0.0016 17.5 0.0 2.4 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KIK63088.1 - 5.2e-08 33.3 15.9 0.036 14.6 0.1 7.2 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KIK63088.1 - 1.7e-07 31.3 20.1 2.2e-05 24.5 2.1 4.9 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK63088.1 - 1.1e-06 29.2 24.8 0.00013 22.5 3.1 5.9 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIK63088.1 - 2.6e-05 24.3 7.8 1.8 9.1 0.4 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK63088.1 - 0.0058 16.8 11.3 0.74 10.1 0.6 4.7 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK63088.1 - 0.0092 16.6 15.6 0.39 11.4 0.1 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK63088.1 - 0.022 14.6 12.3 0.23 11.4 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat R3H PF01424.22 KIK63089.1 - 1.5e-10 40.9 0.0 5.2e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 R3H domain G-patch PF01585.23 KIK63089.1 - 1.5e-07 31.2 0.3 5.3e-07 29.4 0.3 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIK63089.1 - 0.00014 21.9 0.7 0.00066 19.7 0.2 2.6 2 0 0 2 2 2 1 G-patch domain HTH_21 PF13276.6 KIK63089.1 - 0.082 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 HTH-like domain RhoGEF PF00621.20 KIK63091.1 - 3.3e-32 112.2 2.5 5.4e-32 111.5 2.5 1.4 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KIK63091.1 - 5.2e-29 101.7 0.0 8.5e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIK63091.1 - 0.0024 18.0 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PfkB PF00294.24 KIK63092.1 - 5.7e-18 65.3 0.0 7.3e-09 35.3 0.0 3.1 2 1 1 3 3 3 3 pfkB family carbohydrate kinase TPR_19 PF14559.6 KIK63093.1 - 1.2e-14 54.5 3.8 6.2e-07 29.8 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK63093.1 - 2e-11 43.2 2.6 0.83 9.6 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63093.1 - 4.3e-11 42.0 2.9 0.2 11.8 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK63093.1 - 6.8e-11 42.6 1.0 1.1e-05 26.0 0.0 4.7 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK63093.1 - 1.8e-08 34.1 0.1 0.024 15.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK63093.1 - 9.5e-07 29.1 7.3 0.066 14.1 0.2 5.9 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63093.1 - 9e-06 25.9 1.2 0.62 10.4 0.0 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK63093.1 - 1.6e-05 24.8 1.9 0.002 18.1 0.2 3.2 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KIK63093.1 - 2.2e-05 24.6 2.9 0.027 14.7 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIK63093.1 - 0.00063 19.8 3.5 3.5 8.1 0.0 5.0 7 0 0 7 7 7 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIK63093.1 - 0.00073 20.0 2.4 0.0026 18.2 0.3 2.7 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_6 PF13174.6 KIK63093.1 - 0.002 18.6 7.5 2.6 8.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK63093.1 - 0.003 17.2 0.1 6.4 6.6 0.0 3.7 4 0 0 4 4 4 1 TPR repeat TPR_20 PF14561.6 KIK63093.1 - 0.0038 17.5 1.1 5.4 7.4 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK63093.1 - 0.0045 16.9 0.1 47 4.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KIK63093.1 - 0.036 13.7 0.1 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 KIK63093.1 - 0.067 13.4 1.5 0.27 11.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Svf1_C PF17187.4 KIK63094.1 - 6.6e-49 165.9 0.0 1.1e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KIK63094.1 - 3.8e-42 144.1 0.0 5.7e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Peptidase_M48 PF01435.18 KIK63095.1 - 1.4e-13 51.1 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Glyco_hydro_18 PF00704.28 KIK63096.1 - 1.8e-68 231.6 6.0 2.8e-68 231.0 6.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIK63096.1 - 1.5e-05 25.3 5.9 6e-05 23.4 5.9 2.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 KIK63096.1 - 3.1 7.8 8.7 0.28 11.1 2.2 2.7 2 1 1 3 3 3 0 Cellulose-binding domain DnaJ_C PF01556.18 KIK63097.1 - 1e-26 93.8 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK63097.1 - 1.4e-22 79.5 6.9 2.3e-22 78.9 6.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK63097.1 - 1.4e-14 54.1 16.0 2.2e-14 53.6 16.0 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KIK63097.1 - 9.3e-05 22.4 3.6 0.15 12.1 0.8 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KIK63097.1 - 0.00038 20.3 8.9 0.038 13.9 1.1 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KIK63097.1 - 0.056 13.1 0.4 0.056 13.1 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 KIK63097.1 - 0.33 11.0 8.7 1.2 9.2 9.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_9 PF13901.6 KIK63097.1 - 0.59 10.1 2.9 0.9 9.5 2.9 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon NRDD PF13597.6 KIK63097.1 - 2.1 7.0 6.8 0.21 10.3 2.3 1.5 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase Asp PF00026.23 KIK63098.1 - 3.7e-46 158.0 0.1 4.8e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK63098.1 - 3.7e-09 37.1 2.6 4.2e-08 33.6 2.7 2.6 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal FAM76 PF16046.5 KIK63099.1 - 0.0028 17.1 3.0 0.0034 16.8 3.0 1.1 1 0 0 1 1 1 1 FAM76 protein ASD2 PF08687.11 KIK63099.1 - 0.016 14.8 3.0 0.021 14.4 3.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Xpo1 PF08389.12 KIK63100.1 - 2.2e-19 70.0 0.0 8.1e-18 64.9 0.0 3.6 5 0 0 5 5 5 1 Exportin 1-like protein ERAP1_C PF11838.8 KIK63100.1 - 0.014 15.0 0.3 0.11 12.1 0.1 2.5 3 0 0 3 3 3 0 ERAP1-like C-terminal domain HEAT PF02985.22 KIK63100.1 - 0.017 15.3 0.1 2.6 8.5 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat Pkinase PF00069.25 KIK63101.1 - 3.9e-40 137.9 0.0 1.2e-27 96.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63101.1 - 4.1e-21 75.4 0.0 1.5e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK63101.1 - 0.00048 19.0 0.0 0.0008 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK63101.1 - 0.052 13.5 0.3 0.16 11.8 0.3 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK63101.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like NTP_transf_2 PF01909.23 KIK63102.1 - 7.5e-08 32.6 0.0 1.4e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KIK63102.1 - 3.2e-06 27.3 0.0 6.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF2431 PF10354.9 KIK63103.1 - 1.6e-51 174.9 0.0 2.1e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.6 KIK63103.1 - 0.062 13.7 3.3 0.17 12.3 3.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4078 PF13300.6 KIK63104.1 - 6.8e-11 42.3 14.0 2.3e-10 40.7 3.7 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4078) M PF02370.16 KIK63104.1 - 2.5 9.0 6.9 13 6.7 0.4 4.0 3 0 0 3 3 3 0 M protein repeat zf-LITAF-like PF10601.9 KIK63105.1 - 0.72 10.2 2.1 4.6 7.6 0.5 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2070 PF09843.9 KIK63105.1 - 7.9 4.6 13.9 13 4.0 13.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) F-box-like PF12937.7 KIK63106.1 - 0.0014 18.5 0.2 0.0092 15.9 0.2 2.3 1 1 0 1 1 1 1 F-box-like Cwf_Cwc_15 PF04889.12 KIK63106.1 - 3.1 7.5 5.1 5.2 6.7 5.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ADH_zinc_N PF00107.26 KIK63107.1 - 1.3e-22 80.2 0.0 1.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK63107.1 - 1.2e-20 73.5 0.0 2.5e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIK63107.1 - 0.006 17.6 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK63107.1 - 0.024 14.9 0.1 0.066 13.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain PQ-loop PF04193.14 KIK63108.1 - 1.2e-23 82.6 9.4 9.6e-12 44.5 0.1 3.1 2 1 1 3 3 3 2 PQ loop repeat DUF3810 PF12725.7 KIK63108.1 - 0.2 11.0 2.1 0.26 10.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Tom5 PF10642.9 KIK63108.1 - 1.7 8.7 4.4 13 5.9 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase ThiS PF02597.20 KIK63109.1 - 5.7e-07 30.1 0.0 7.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ThiS family Lactamase_B PF00753.27 KIK63110.1 - 0.0031 17.6 0.1 0.0043 17.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B PF00753.27 KIK63111.1 - 0.14 12.2 4.0 0.67 9.9 4.0 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Sigma_reg_N PF13800.6 KIK63113.1 - 0.074 13.4 2.2 0.35 11.2 0.0 2.3 1 1 1 2 2 2 0 Sigma factor regulator N-terminal TAF4 PF05236.14 KIK63114.1 - 3.1e-33 115.7 0.8 4.8e-33 115.1 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family G_path_suppress PF15991.5 KIK63114.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.5 2 1 0 2 2 2 0 G-protein pathway suppressor Erg28 PF03694.13 KIK63116.1 - 2.6e-42 143.7 3.2 3.1e-42 143.4 3.2 1.1 1 0 0 1 1 1 1 Erg28 like protein GIIM PF08388.11 KIK63116.1 - 0.066 13.3 0.1 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Group II intron, maturase-specific domain F-box-like PF12937.7 KIK63117.1 - 0.001 18.9 0.2 0.0089 15.9 0.1 2.5 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.18 KIK63118.1 - 1.9e-06 27.9 8.0 3e-06 27.2 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK63118.1 - 0.00034 19.7 0.1 0.00052 19.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ORC_WH_C PF18137.1 KIK63119.1 - 4.5e-38 130.5 0.2 3.9e-37 127.4 0.1 2.5 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KIK63119.1 - 4.8e-24 85.1 1.9 2.4e-23 82.8 1.9 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus LisH PF08513.11 KIK63119.1 - 0.031 14.2 0.2 0.076 13.0 0.2 1.7 1 0 0 1 1 1 0 LisH CRAL_TRIO PF00650.20 KIK63120.1 - 1.6e-24 86.4 0.0 2.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK63120.1 - 8.7e-11 41.8 0.1 4.1e-10 39.7 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain tRNA-synt_2 PF00152.20 KIK63121.1 - 1e-57 195.6 0.0 1.8e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK63121.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIK63121.1 - 0.00032 20.2 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF2156 PF09924.9 KIK63121.1 - 0.0062 15.6 0.0 5.4 5.9 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2156) Hydant_A_N PF05378.13 KIK63121.1 - 0.096 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Ank_4 PF13637.6 KIK63122.1 - 4.7e-17 62.1 0.2 3.7e-07 30.6 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK63122.1 - 9.8e-12 45.3 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK63122.1 - 2.1e-11 43.8 0.0 6.6e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK63122.1 - 1.9e-09 36.9 0.0 6.3e-06 26.1 0.1 4.1 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KIK63122.1 - 3.3e-09 36.8 0.2 6.5e-05 23.2 0.2 4.1 4 0 0 4 4 4 1 Ankyrin repeat GATA PF00320.27 KIK63123.1 - 2.2e-14 52.8 5.4 4.2e-14 51.9 5.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KIK63123.1 - 0.0057 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KIK63123.1 - 0.056 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 PAS domain LRR_4 PF12799.7 KIK63124.1 - 7.8e-38 127.9 30.4 1.8e-08 34.5 0.1 6.9 5 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK63124.1 - 7.1e-28 96.2 26.0 1.7e-07 30.9 1.3 5.9 4 1 0 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KIK63124.1 - 6e-21 74.7 10.3 1.5e-09 37.6 0.7 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KIK63124.1 - 1e-08 34.5 22.1 5.3 8.0 0.0 10.3 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 KIK63124.1 - 7e-07 28.8 27.6 0.61 10.3 0.0 9.8 12 0 0 12 12 12 3 Leucine Rich repeat PRMT5 PF05185.16 KIK63125.1 - 1.8e-67 226.5 0.0 2.9e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KIK63125.1 - 3.9e-65 219.6 0.0 5.2e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KIK63125.1 - 4.9e-58 195.9 0.0 7.3e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 KIK63125.1 - 0.0023 18.6 0.0 0.0058 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIK63125.1 - 0.067 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 KIK63125.1 - 0.13 13.0 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2057 PF09829.9 KIK63126.1 - 0.42 10.8 3.5 0.63 10.2 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) HPHLAWLY PF14925.6 KIK63126.1 - 4.5 5.8 9.4 5.4 5.6 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function SUI1 PF01253.22 KIK63128.1 - 1.6e-25 89.5 1.4 3e-25 88.5 1.4 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Na_Ca_ex PF01699.24 KIK63129.1 - 8.6e-43 145.9 46.2 1e-26 93.7 12.4 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Ninjurin PF04923.12 KIK63129.1 - 0.13 12.2 0.4 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Ninjurin DUF4079 PF13301.6 KIK63129.1 - 0.65 10.1 4.9 0.84 9.8 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Arylesterase PF01731.20 KIK63132.1 - 0.0015 18.7 0.3 0.023 14.9 0.3 2.8 1 1 0 1 1 1 1 Arylesterase KilA-N PF04383.13 KIK63133.1 - 0.0071 16.2 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain PFK PF00365.20 KIK63134.1 - 6.3e-185 613.1 1.1 1.3e-85 287.2 0.1 3.0 3 0 0 3 3 3 3 Phosphofructokinase DAGK_cat PF00781.24 KIK63134.1 - 0.11 12.2 0.2 0.33 10.6 0.2 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain WLM PF08325.10 KIK63135.1 - 9.9e-33 113.8 3.3 3.5e-32 112.0 0.4 2.7 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KIK63135.1 - 2.5e-06 27.7 0.2 5.8e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 KIK63135.1 - 4.2e-05 22.8 1.6 8.6e-05 21.8 1.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.9 KIK63135.1 - 0.02 14.8 0.1 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 SprT-like family Vps36-NZF-N PF16988.5 KIK63135.1 - 0.16 11.4 2.4 0.68 9.4 2.4 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RasGAP PF00616.19 KIK63136.1 - 1e-58 198.5 0.0 5.5e-58 196.1 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KIK63136.1 - 3.9e-37 127.5 0.4 3.9e-37 127.5 0.4 2.0 2 0 0 2 2 2 1 RasGAP C-terminus CTK3 PF12243.8 KIK63136.1 - 0.1 12.6 0.5 9.9 6.2 0.2 2.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 BRO1 PF03097.18 KIK63137.1 - 2.1e-103 346.1 2.1 2.8e-103 345.7 0.0 2.1 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIK63137.1 - 9e-76 255.0 19.0 1.4e-75 254.3 19.0 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FTO_CTD PF12934.7 KIK63137.1 - 0.01 15.6 1.4 0.01 15.6 1.4 3.1 3 1 0 3 3 3 0 FTO C-terminal domain ATP-synt_E_2 PF08112.11 KIK63137.1 - 0.022 15.0 3.6 0.024 14.9 0.8 2.4 2 0 0 2 2 2 0 ATP synthase epsilon subunit VSG_B PF13206.6 KIK63137.1 - 1.2 8.4 7.2 0.9 8.7 5.5 1.6 1 1 0 1 1 1 0 Trypanosomal VSG domain FapA PF03961.13 KIK63137.1 - 3 6.4 5.4 2.9 6.4 4.2 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A ING PF12998.7 KIK63137.1 - 5 7.8 10.2 5.2 7.7 1.1 3.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Tex_N PF09371.10 KIK63137.1 - 5.1 6.7 11.0 0.5 10.0 0.7 3.4 3 0 0 3 3 3 0 Tex-like protein N-terminal domain MaoC_dehydratas PF01575.19 KIK63138.1 - 7.9e-30 103.0 0.0 1.5e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIK63138.1 - 0.0048 17.0 0.0 0.057 13.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Na_Ca_ex PF01699.24 KIK63139.1 - 3.2e-39 134.3 40.1 4.7e-21 75.3 15.1 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4199 PF13858.6 KIK63139.1 - 0.056 13.8 0.4 0.056 13.8 0.4 3.5 3 2 0 4 4 4 0 Protein of unknown function (DUF4199) DUF1129 PF06570.11 KIK63139.1 - 2.1 7.8 12.1 2.9 7.3 0.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) Cortexin PF11057.8 KIK63139.1 - 2.6 7.9 6.2 1.6 8.6 0.2 3.4 4 0 0 4 4 4 0 Cortexin of kidney Orf78 PF06024.12 KIK63139.1 - 8.5 6.7 6.0 2 8.8 0.1 2.9 2 1 2 4 4 4 0 Orf78 (ac78) DUF5383 PF17355.2 KIK63139.1 - 8.6 6.8 6.3 0.91 9.9 0.1 2.6 4 0 0 4 4 4 0 Family of unknown function (DUF5383) LRR_4 PF12799.7 KIK63140.1 - 0.00014 22.2 1.4 5.3 7.6 0.0 4.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK63140.1 - 0.00047 19.9 0.3 0.15 11.8 0.0 3.6 2 1 0 2 2 2 1 Leucine rich repeat F-box-like PF12937.7 KIK63140.1 - 0.0016 18.3 3.4 0.0022 17.9 0.8 2.6 2 1 0 2 2 2 1 F-box-like LRR_1 PF00560.33 KIK63140.1 - 0.91 10.3 3.4 1.8e+02 3.3 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat CS PF04969.16 KIK63141.1 - 2.5e-08 34.8 0.0 5.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 CS domain MMS19_N PF14500.6 KIK63141.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Dysbindin PF04440.16 KIK63141.1 - 0.38 10.9 4.1 0.65 10.1 3.2 1.9 1 1 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Cullin PF00888.22 KIK63142.1 - 2.4e-208 693.7 2.1 3.1e-208 693.3 2.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK63142.1 - 4.7e-28 97.0 2.2 1.6e-27 95.3 2.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KIK63142.1 - 0.066 13.3 0.1 0.066 13.3 0.1 2.7 3 0 0 3 3 3 0 SecA Wing and Scaffold domain Yos9_DD PF17880.1 KIK63142.1 - 0.18 11.9 1.1 0.5 10.5 0.3 2.2 2 0 0 2 2 2 0 Yos9 dimerzation domain DEAD PF00270.29 KIK63143.1 - 3.8e-17 62.6 0.0 1.4e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 KIK63143.1 - 1.2e-15 57.2 0.0 4.6e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 RQC domain Helicase_C PF00271.31 KIK63143.1 - 1.4e-13 51.1 0.2 5.9e-12 45.9 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIK63143.1 - 8.5e-13 48.8 5.0 2.4e-12 47.4 5.0 1.8 1 0 0 1 1 1 1 RecQ zinc-binding SecA_DEAD PF07517.14 KIK63143.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain DUF3421 PF11901.8 KIK63144.1 - 1.4e-32 112.1 0.2 2.4e-32 111.3 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) XLF PF09302.11 KIK63145.1 - 2.6e-08 34.2 0.5 6.2e-08 33.0 0.5 1.6 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Macoilin PF09726.9 KIK63145.1 - 6.8 5.1 12.4 11 4.5 12.4 1.3 1 0 0 1 1 1 0 Macoilin family G-patch PF01585.23 KIK63146.1 - 9.8e-10 38.2 0.1 1.7e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 KIK63146.1 - 2.8e-09 37.2 0.5 8.5e-09 35.7 0.0 2.2 2 1 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KIK63146.1 - 0.044 14.1 0.0 0.54 10.6 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain G-patch_2 PF12656.7 KIK63146.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 G-patch domain Cyclin_N PF00134.23 KIK63148.1 - 1e-42 144.8 0.3 4.4e-42 142.8 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK63148.1 - 1.2e-24 86.7 0.1 2.1e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain adh_short PF00106.25 KIK63149.1 - 3.7e-84 281.1 17.3 8.2e-45 152.7 3.9 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK63149.1 - 1.8e-68 230.6 12.0 5.2e-34 117.8 1.5 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK63149.1 - 9.3e-26 90.8 11.2 5.5e-15 55.7 1.3 2.5 3 0 0 3 3 3 2 KR domain THF_DHG_CYH_C PF02882.19 KIK63149.1 - 0.0022 17.3 3.3 0.22 10.8 0.3 3.1 2 1 1 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KIK63149.1 - 0.0047 16.8 8.6 0.027 14.4 1.1 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding PF02629.19 KIK63149.1 - 0.011 16.4 0.3 11 6.7 0.1 3.1 2 0 0 2 2 2 0 CoA binding domain Phage_rep_O PF04492.13 KIK63149.1 - 0.17 12.5 0.2 48 4.6 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage replication protein O Shikimate_DH PF01488.20 KIK63149.1 - 0.52 10.4 2.2 21 5.2 0.1 3.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PglL_A PF15864.5 KIK63149.1 - 0.6 9.9 7.4 4.8 7.0 0.8 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase TOM13 PF08219.11 KIK63151.1 - 2.5e-13 49.8 0.0 8.2e-13 48.1 0.0 1.9 1 0 0 1 1 1 1 Outer membrane protein TOM13 RTX PF02382.15 KIK63151.1 - 0.12 12.0 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein zf-C2H2 PF00096.26 KIK63152.1 - 6.8e-06 26.3 1.2 0.014 15.8 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK63152.1 - 6.8e-05 23.4 1.4 0.089 13.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK63152.1 - 0.0098 16.2 0.8 0.096 13.0 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIK63152.1 - 0.18 12.1 2.2 0.78 10.1 2.4 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIK63152.1 - 0.2 12.0 1.4 3.5 8.0 1.7 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Stevor PF17410.2 KIK63153.1 - 0.00067 19.3 0.1 0.001 18.7 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Amnionless PF14828.6 KIK63153.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless Trp_oprn_chp PF09534.10 KIK63153.1 - 0.086 12.6 4.4 0.24 11.2 4.4 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Romo1 PF10247.9 KIK63153.1 - 0.15 12.4 1.0 0.31 11.4 1.0 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Mid2 PF04478.12 KIK63153.1 - 0.17 11.7 0.5 0.37 10.6 0.1 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor ATF7IP_BD PF16788.5 KIK63153.1 - 0.83 9.7 3.5 0.42 10.7 1.0 1.7 2 0 0 2 2 2 0 ATF-interacting protein binding domain Stevor PF17410.2 KIK63155.1 - 0.0073 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Patched PF02460.18 KIK63157.1 - 0.019 13.1 1.5 0.023 12.8 1.5 1.0 1 0 0 1 1 1 0 Patched family YtpI PF14007.6 KIK63158.1 - 0.0077 16.3 0.8 0.016 15.4 0.8 1.4 1 0 0 1 1 1 1 YtpI-like protein Fungal_trans PF04082.18 KIK63161.1 - 1.2e-08 34.4 1.3 2e-08 33.6 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK63161.1 - 0.00032 20.7 10.4 0.00054 20.0 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KIK63162.1 - 3.9e-27 95.3 0.7 6.2e-27 94.7 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK63162.1 - 4e-19 68.6 0.5 7.5e-19 67.7 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIK63162.1 - 2.2e-16 59.8 0.0 4.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIK63162.1 - 3.2e-16 60.0 0.1 1.2e-15 58.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK63162.1 - 0.00033 20.9 0.6 0.00064 20.0 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoA_transf_3 PF02515.17 KIK63163.1 - 1.5e-53 182.3 0.0 5.9e-53 180.3 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III CoA_transf_3 PF02515.17 KIK63164.1 - 9.7e-60 202.6 0.0 1.7e-59 201.8 0.0 1.3 1 1 0 1 1 1 1 CoA-transferase family III Glyco_hydro_79C PF16862.5 KIK63165.1 - 3e-16 60.2 0.0 8.6e-16 58.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KIK63165.1 - 0.1 11.5 0.0 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain SH3_1 PF00018.28 KIK63166.1 - 0.00085 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK63166.1 - 0.0013 18.5 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Sec63 PF02889.16 KIK63168.1 - 1.1e-156 519.6 0.1 4.1e-86 288.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KIK63168.1 - 1e-46 158.9 0.1 4.6e-25 88.4 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KIK63168.1 - 3.9e-34 117.2 0.1 9.4e-34 115.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KIK63168.1 - 2.3e-23 83.1 0.0 1.9e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK63168.1 - 6e-16 58.8 0.0 3.3e-08 33.9 0.0 4.5 3 2 1 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK63168.1 - 9.1e-06 26.0 0.0 0.052 13.8 0.0 3.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KIK63168.1 - 0.0034 16.9 0.0 0.081 12.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 KIK63168.1 - 0.0093 16.3 0.1 0.64 10.3 0.1 2.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIK63168.1 - 0.013 14.6 0.0 0.39 9.7 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Nop14 PF04147.12 KIK63168.1 - 3.2 5.9 15.9 6.1 4.9 15.9 1.3 1 0 0 1 1 1 0 Nop14-like family Rsa3 PF14615.6 KIK63169.1 - 1.2e-12 47.2 0.0 1.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 AIRC PF00731.20 KIK63170.1 - 3.3e-54 182.5 0.5 3.3e-54 182.5 0.5 2.0 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.22 KIK63170.1 - 2.7e-52 176.8 0.0 4.1e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KIK63170.1 - 1.3e-20 72.8 0.0 3.3e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KIK63170.1 - 0.00041 19.9 0.1 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain MscL PF01741.18 KIK63171.1 - 5.3e-19 68.7 0.5 6.5e-19 68.4 0.5 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-C3HC4_3 PF13920.6 KIK63171.1 - 0.036 13.9 0.7 0.053 13.4 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KIK63171.1 - 0.04 13.9 1.7 0.065 13.3 1.7 1.2 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 KIK63171.1 - 0.21 11.5 2.9 0.34 10.8 2.9 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 KIK63171.1 - 0.55 10.0 5.5 0.9 9.3 5.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Steroid_dh PF02544.16 KIK63172.1 - 4.9e-34 117.5 0.9 7.8e-34 116.8 0.9 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KIK63172.1 - 1.1e-06 28.3 0.1 2.9e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin family Mt_ATP-synt_D PF05873.12 KIK63173.1 - 2.1e-16 60.1 1.5 2.5e-16 59.9 1.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Hrs_helical PF12210.8 KIK63173.1 - 0.0076 16.8 1.2 5.3 7.7 0.0 2.6 2 1 1 3 3 3 2 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF948 PF06103.11 KIK63173.1 - 0.067 13.5 1.6 2.2 8.6 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ShlB PF03865.13 KIK63174.1 - 0.00036 20.1 1.9 0.13 11.7 0.2 2.4 2 0 0 2 2 2 2 Haemolysin secretion/activation protein ShlB/FhaC/HecB Porin_4 PF13609.6 KIK63174.1 - 0.012 15.4 0.7 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 Gram-negative porin TFIIS_C PF01096.18 KIK63176.1 - 6.2e-15 54.8 0.6 6.2e-15 54.8 0.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIK63176.1 - 1.3e-08 34.5 0.7 1.3e-08 34.5 0.7 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KIK63176.1 - 0.00029 20.8 1.0 0.061 13.3 0.3 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain C1_1 PF00130.22 KIK63176.1 - 0.027 14.3 3.8 0.29 11.0 0.7 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH_5 PF14279.6 KIK63176.1 - 0.049 13.5 1.8 0.085 12.7 0.0 2.1 3 0 0 3 3 3 0 HNH endonuclease zinc-ribbons_6 PF07191.12 KIK63176.1 - 0.064 13.3 1.7 0.83 9.7 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbons L_biotic_typeA PF04604.13 KIK63176.1 - 0.13 12.2 0.5 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Type-A lantibiotic PADR1 PF08063.12 KIK63176.1 - 0.18 11.6 4.0 1.3 8.9 0.2 2.4 2 1 0 2 2 2 0 PADR1 (NUC008) domain PhnA_Zn_Ribbon PF08274.12 KIK63176.1 - 0.23 11.4 7.6 10 6.1 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon PHD PF00628.29 KIK63176.1 - 0.43 10.5 5.4 17 5.4 0.0 2.7 2 1 0 2 2 2 0 PHD-finger zf-Sec23_Sec24 PF04810.15 KIK63176.1 - 1 9.4 7.3 0.36 10.9 2.8 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF572 PF04502.13 KIK63177.1 - 2.5e-81 273.9 10.6 2.8e-81 273.7 10.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Osteoregulin PF07175.11 KIK63177.1 - 0.009 16.2 5.2 0.017 15.3 1.0 2.2 1 1 1 2 2 2 1 Osteoregulin zf-FCS PF06467.14 KIK63177.1 - 0.016 15.1 0.8 0.64 10.0 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif COG4 PF08318.12 KIK63178.1 - 1.2e-92 310.5 0.9 1.6e-92 310.2 0.1 1.6 2 0 0 2 2 2 1 COG4 transport protein JIP_LZII PF16471.5 KIK63178.1 - 0.0016 18.6 0.1 0.0058 16.8 0.1 2.0 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II RINT1_TIP1 PF04437.13 KIK63178.1 - 0.0051 15.8 0.1 0.034 13.1 0.0 2.3 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Pkip-1 PF06878.11 KIK63178.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Pkip-1 protein AAA_assoc PF14363.6 KIK63178.1 - 0.11 12.9 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA DUF2013 PF09431.10 KIK63179.1 - 3.2e-51 173.1 0.3 3.2e-51 173.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Kinetochor_Ybp2 PF08568.10 KIK63180.1 - 1.6e-20 73.2 0.1 4.2e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin HSBP1 PF06825.12 KIK63181.1 - 2.1e-17 62.7 2.6 2.3e-17 62.6 2.6 1.0 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 KIK63181.1 - 0.012 15.7 0.4 0.015 15.3 0.4 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KIK63181.1 - 0.073 13.4 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NmrA PF05368.13 KIK63182.1 - 2.2e-07 30.7 0.1 3.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK63182.1 - 2.6e-06 27.5 0.1 3.8e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIK63182.1 - 0.0043 17.5 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KIK63182.1 - 0.0052 16.3 0.0 0.028 13.9 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK63182.1 - 0.013 14.5 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KIK63183.1 - 5.5e-07 29.4 0.2 9.1e-07 28.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK63183.1 - 2.6e-05 24.2 0.1 3.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIK63183.1 - 0.002 18.6 0.2 0.02 15.3 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KIK63183.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK63183.1 - 0.18 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CBF PF03914.17 KIK63184.1 - 2.9e-27 95.8 1.8 2.9e-27 95.8 1.8 3.0 4 0 0 4 4 4 1 CBF/Mak21 family RNA_pol_3_Rpc31 PF11705.8 KIK63184.1 - 0.027 14.8 9.5 0.054 13.7 9.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MOR2-PAG1_C PF14225.6 KIK63184.1 - 0.074 12.9 0.2 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Astro_capsid_p PF12226.8 KIK63184.1 - 0.18 10.9 7.2 0.28 10.3 7.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pes-10 PF07149.11 KIK63184.1 - 0.32 10.0 5.2 8.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Pes-10 FAM176 PF14851.6 KIK63184.1 - 0.79 9.4 5.1 1.9 8.1 4.6 1.8 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.12 KIK63184.1 - 3.9 5.6 11.7 5.2 5.2 7.4 2.3 2 0 0 2 2 2 0 Nop14-like family Vfa1 PF08432.10 KIK63184.1 - 5.4 7.3 9.2 1.8 8.9 6.0 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 KIK63184.1 - 5.9 6.2 9.0 1.1 8.6 4.8 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Cpn60_TCP1 PF00118.24 KIK63185.1 - 5.4e-154 513.5 0.3 6.1e-154 513.3 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_A_bac PF01000.26 KIK63186.1 - 1.2e-22 80.4 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIK63186.1 - 1.2e-21 75.9 0.0 2e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MMtag PF10159.9 KIK63187.1 - 7.7e-31 106.2 2.1 7.7e-31 106.2 2.1 3.3 2 1 1 3 3 3 1 Multiple myeloma tumor-associated Borrelia_P83 PF05262.11 KIK63187.1 - 0.47 8.9 14.5 0.58 8.6 14.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hamartin PF04388.12 KIK63187.1 - 2.5 6.7 7.2 2.8 6.5 7.2 1.0 1 0 0 1 1 1 0 Hamartin protein Lactamase_B_2 PF12706.7 KIK63188.1 - 4.3e-13 49.2 0.6 4e-12 46.1 0.6 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIK63188.1 - 2.2e-07 30.5 0.0 6.4e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIK63188.1 - 0.00025 21.1 0.1 0.00051 20.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily YchF-GTPase_C PF06071.13 KIK63189.1 - 2.3e-35 120.6 0.1 1.1e-34 118.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KIK63189.1 - 1.5e-19 70.1 0.0 5.6e-18 65.1 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK63189.1 - 1.4e-06 27.9 0.0 3.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KIK63189.1 - 0.0065 15.5 0.6 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB BetaGal_dom3 PF13363.6 KIK63189.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 NlpE PF04170.12 KIK63189.1 - 0.14 13.2 0.1 0.28 12.2 0.1 1.4 1 0 0 1 1 1 0 NlpE N-terminal domain Dynamin_N PF00350.23 KIK63189.1 - 0.16 12.0 0.6 2.4 8.2 0.5 2.7 1 1 0 1 1 1 0 Dynamin family TIP49 PF06068.13 KIK63190.1 - 1.1e-132 442.5 0.1 1.2e-131 439.1 0.1 2.0 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIK63190.1 - 7.1e-15 54.9 0.1 2.7e-14 53.0 0.1 2.1 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KIK63190.1 - 2.8e-07 31.0 0.1 7.3e-05 23.2 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIK63190.1 - 5.2e-05 22.7 0.6 0.0027 17.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIK63190.1 - 0.00015 21.5 0.5 0.24 11.1 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK63190.1 - 0.00033 21.0 0.4 0.47 10.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK63190.1 - 0.0013 19.1 0.1 0.49 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK63190.1 - 0.0034 17.8 0.8 0.011 16.2 0.1 2.2 3 0 0 3 3 3 1 AAA ATPase domain DnaB_C PF03796.15 KIK63190.1 - 0.0091 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 KIK63190.1 - 0.01 15.8 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.12 KIK63190.1 - 0.027 14.3 0.1 0.19 11.5 0.0 2.1 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 KIK63190.1 - 0.037 14.3 0.0 0.081 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KIK63190.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KIK63190.1 - 0.04 13.2 0.2 0.36 10.1 0.1 2.5 3 0 0 3 3 3 0 Zeta toxin Sigma54_activat PF00158.26 KIK63190.1 - 0.095 12.4 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KIK63190.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK63190.1 - 0.12 12.5 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NmrA PF05368.13 KIK63191.1 - 4.9e-19 68.8 0.0 1.8e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK63191.1 - 8.2e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIK63191.1 - 0.00028 20.4 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK63191.1 - 0.0025 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK63191.1 - 0.015 14.7 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK63191.1 - 0.028 13.6 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 KIK63191.1 - 0.038 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 KIK63191.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DEAD PF00270.29 KIK63192.1 - 4.1e-53 179.8 0.0 4.5e-52 176.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63192.1 - 4.4e-15 56.0 0.0 1.5e-13 51.1 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63192.1 - 8.2e-07 29.2 0.0 3.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 KIK63192.1 - 0.011 16.2 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK63192.1 - 0.024 15.0 0.0 6.7 7.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF2443 PF10398.9 KIK63192.1 - 0.081 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) UbiA PF01040.18 KIK63193.1 - 6.1e-57 192.8 17.6 7.9e-57 192.4 17.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Collar PF07484.12 KIK63193.1 - 0.054 13.5 1.0 0.16 12.0 1.0 1.8 1 1 0 1 1 1 0 Phage Tail Collar Domain Homeodomain PF00046.29 KIK63194.1 - 9.1e-19 67.1 3.1 1.7e-18 66.2 3.1 1.5 1 0 0 1 1 1 1 Homeodomain CAF20 PF17052.5 KIK63194.1 - 0.17 12.0 1.5 0.33 11.1 1.5 1.4 1 0 0 1 1 1 0 Cap associated factor zf-C2H2_jaz PF12171.8 KIK63198.1 - 0.0036 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK63198.1 - 0.0053 17.1 0.3 0.0087 16.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type ADD_ATRX PF17981.1 KIK63198.1 - 0.032 14.1 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Cysteine Rich ADD domain OrsD PF12013.8 KIK63198.1 - 0.034 14.6 0.4 0.057 13.9 0.4 1.4 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 KIK63198.1 - 0.037 14.3 0.2 0.053 13.8 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) MRNIP PF15749.5 KIK63198.1 - 0.039 14.7 0.6 0.05 14.3 0.6 1.2 1 0 0 1 1 1 0 MRN-interacting protein Casc1_N PF15927.5 KIK63198.1 - 0.51 10.0 16.1 0.94 9.1 16.1 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus CTU2 PF10288.9 KIK63198.1 - 0.99 9.7 3.8 1.7 8.9 3.8 1.4 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Oxidored_molyb PF00174.19 KIK63199.1 - 5.8e-58 195.3 0.0 8.2e-58 194.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIK63199.1 - 3.5e-19 69.2 0.2 7.2e-19 68.2 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain COX6B PF02297.17 KIK63200.1 - 4.6e-19 68.4 5.9 5.4e-19 68.2 5.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KIK63200.1 - 0.0076 16.4 0.5 0.023 14.8 0.5 1.9 1 1 0 1 1 1 1 CHCH domain Prp18 PF02840.15 KIK63201.1 - 1.1e-61 207.1 0.1 1.1e-61 207.1 0.1 2.3 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 KIK63201.1 - 1.7e-10 40.3 4.8 1.7e-10 40.3 4.8 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Rrn6 PF10214.9 KIK63201.1 - 0.13 10.7 5.6 0.23 9.9 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MAS20 PF02064.15 KIK63201.1 - 3.4 7.8 11.4 0.17 12.0 2.7 2.6 2 1 0 2 2 2 0 MAS20 protein import receptor HSP70 PF00012.20 KIK63201.1 - 5.2 5.1 7.4 0.17 10.1 1.5 1.6 2 0 0 2 2 2 0 Hsp70 protein CAF-1_p150 PF11600.8 KIK63201.1 - 5.5 6.7 32.0 0.48 10.1 18.6 2.9 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Myb_DNA-binding PF00249.31 KIK63202.1 - 1.4e-10 41.2 0.2 3.1e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KIK63202.1 - 3.9e-10 39.9 0.0 1.2e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KIK63202.1 - 0.00019 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIK63202.1 - 0.56 10.1 10.1 1.3 8.9 10.1 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type Ras PF00071.22 KIK63203.1 - 2.8e-46 157.1 0.0 3.2e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK63203.1 - 3.7e-18 65.9 0.0 5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK63203.1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK63203.1 - 1.8e-06 27.9 0.2 0.00037 20.4 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIK63203.1 - 4.7e-06 26.3 0.3 1.7e-05 24.4 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK63203.1 - 0.00031 20.8 0.2 0.00049 20.2 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK63203.1 - 0.024 15.0 0.4 0.17 12.2 0.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain ImcF-related_N PF14331.6 KIK63203.1 - 0.042 13.2 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain ATPase_2 PF01637.18 KIK63203.1 - 0.11 12.3 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF5040 PF16443.5 KIK63203.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Pkinase_Tyr PF07714.17 KIK63204.1 - 9.6e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK63204.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ras PF00071.22 KIK63205.1 - 1.8e-37 128.5 0.0 2.3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Pkinase_Tyr PF07714.17 KIK63205.1 - 2e-12 46.9 0.1 4e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Roc PF08477.13 KIK63205.1 - 1.2e-11 44.9 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KIK63205.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RsgA_GTPase PF03193.16 KIK63205.1 - 0.00021 21.2 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIK63205.1 - 0.012 15.6 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF5040 PF16443.5 KIK63205.1 - 0.063 12.7 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) NB-ARC PF00931.22 KIK63205.1 - 0.21 10.7 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pkinase_Tyr PF07714.17 KIK63206.1 - 3.3e-06 26.6 0.0 3.6e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK63206.1 - 0.00044 19.7 0.0 0.00046 19.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ras PF00071.22 KIK63207.1 - 5e-36 123.8 0.0 6.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Pkinase_Tyr PF07714.17 KIK63207.1 - 2.8e-12 46.5 0.0 4.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Roc PF08477.13 KIK63207.1 - 3.5e-11 43.4 0.0 5.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KIK63207.1 - 9e-09 35.1 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Arf PF00025.21 KIK63207.1 - 2.3e-06 27.2 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK63207.1 - 0.0016 18.4 1.4 1.8 8.4 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KIK63207.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK63207.1 - 0.17 12.2 0.2 0.54 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Pkinase_Tyr PF07714.17 KIK63208.1 - 8.4e-14 51.5 0.0 1.1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK63208.1 - 1.3e-09 37.9 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4351 PF14261.6 KIK63208.1 - 0.15 12.1 0.5 0.6 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) DnaJ PF00226.31 KIK63210.1 - 2.7e-24 85.1 1.1 6.5e-24 83.8 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 KIK63210.1 - 4.9e-10 39.5 1.0 1.2e-09 38.2 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK63210.1 - 6.3e-10 39.1 0.8 1.5e-09 37.9 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIK63210.1 - 1.2e-06 28.8 1.8 0.0017 18.7 0.2 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KIK63210.1 - 3.9e-05 24.1 2.6 0.34 11.9 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK63210.1 - 0.00011 22.7 5.1 0.00011 22.7 0.1 3.0 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK63210.1 - 0.00059 20.2 5.6 0.28 11.7 0.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KIK63210.1 - 0.0061 16.5 0.4 0.0061 16.5 0.4 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger SET_assoc PF11767.8 KIK63210.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-Tim10_DDP PF02953.15 KIK63211.1 - 6.5e-25 86.6 3.3 8.8e-25 86.1 3.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Arg_decarbox_C PF17944.1 KIK63211.1 - 0.11 13.1 0.1 1.3 9.6 0.0 2.1 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension Ras PF00071.22 KIK63212.1 - 5.4e-49 165.9 0.0 6.1e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK63212.1 - 8.9e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK63212.1 - 1.2e-06 28.6 0.4 0.0016 18.3 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase Arf PF00025.21 KIK63212.1 - 8.8e-06 25.3 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK63212.1 - 0.0002 21.0 0.1 0.001 18.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ImcF-related_N PF14331.6 KIK63212.1 - 0.00063 19.2 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 ImcF-related N-terminal domain MMR_HSR1 PF01926.23 KIK63212.1 - 0.0023 18.0 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KIK63212.1 - 0.093 12.0 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 KIK63212.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK63212.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF5040 PF16443.5 KIK63212.1 - 0.19 11.1 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) AAA_16 PF13191.6 KIK63212.1 - 0.19 12.1 0.6 0.41 11.0 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain Pro_isomerase PF00160.21 KIK63213.1 - 8.5e-44 149.6 0.0 9.5e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIK63214.1 - 7.4e-14 51.3 0.1 1.3e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD3 PF05879.12 KIK63215.1 - 3.7e-251 835.4 1.5 4.8e-251 835.1 1.5 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KIK63215.1 - 5.8e-07 29.6 0.0 2.1e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 KIK63215.1 - 4.6e-06 26.1 0.2 1e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KIK63215.1 - 2.1e-05 24.7 0.0 4.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 KIK63215.1 - 0.0018 18.6 0.0 0.006 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KIK63215.1 - 0.11 12.7 0.1 0.36 11.1 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIK63215.1 - 0.16 12.4 1.3 0.82 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK63215.1 - 1.7 9.0 4.2 3.3 8.0 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain WGG PF10273.9 KIK63216.1 - 4.1e-26 91.4 0.1 7.7e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KIK63216.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.8 2 1 1 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PNP_UDP_1 PF01048.20 KIK63217.1 - 1.6e-34 119.2 0.0 1.8e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily LSM PF01423.22 KIK63218.1 - 7.5e-16 57.6 0.0 9.9e-16 57.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain LAL_C2 PF18603.1 KIK63218.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 F-box-like PF12937.7 KIK63219.1 - 6.2e-07 29.2 3.1 7.5e-06 25.8 1.3 2.6 2 0 0 2 2 2 2 F-box-like MBOAT_2 PF13813.6 KIK63220.1 - 1.3e-15 57.4 1.8 1.3e-15 57.4 1.8 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PAN_4 PF14295.6 KIK63221.1 - 0.027 14.4 0.6 0.69 9.9 0.1 2.5 2 0 0 2 2 2 0 PAN domain MARVEL PF01284.23 KIK63222.1 - 5.5e-11 42.7 11.5 8.7e-11 42.0 11.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain ATG27 PF09451.10 KIK63223.1 - 2.3e-18 67.0 0.1 6.6e-18 65.5 0.1 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KIK63223.1 - 7.5e-13 48.1 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 KIK63223.1 - 2.8e-10 40.4 0.6 0.0001 22.4 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat NusG_II PF07009.11 KIK63223.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 NusG domain II SH3_1 PF00018.28 KIK63224.1 - 4.1e-11 42.3 0.1 6.9e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK63224.1 - 1.1e-09 38.0 0.0 2.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK63224.1 - 2e-08 33.8 0.0 3.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Cullin_Nedd8 PF10557.9 KIK63224.1 - 0.071 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Cullin protein neddylation domain U1snRNP70_N PF12220.8 KIK63225.1 - 3.1e-26 91.8 0.7 5.3e-26 91.1 0.7 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KIK63225.1 - 1.6e-16 59.8 0.0 2.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4799 PF16056.5 KIK63225.1 - 9.3 5.3 11.3 51 2.9 11.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4799) Maf1 PF09174.10 KIK63226.1 - 1.3e-34 119.8 0.0 5.7e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator NUDIX_2 PF13869.6 KIK63227.1 - 5.3e-84 280.5 0.0 6.1e-84 280.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase eIF3_N PF09440.10 KIK63228.1 - 1.1e-47 161.8 2.6 1.1e-47 161.8 2.6 2.5 3 1 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KIK63228.1 - 1e-08 35.6 0.4 3.2e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 PCI domain PBECR3 PF18812.1 KIK63228.1 - 0.078 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 NAPRTase PF04095.16 KIK63229.1 - 1.6e-61 208.0 0.0 2.1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KIK63229.1 - 1.1e-38 132.5 0.0 1.6e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNase_PH PF01138.21 KIK63230.1 - 6.2e-32 110.9 0.1 2.4e-31 109.0 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK63230.1 - 0.00022 21.2 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.17 KIK63231.1 - 6.2e-54 182.1 0.0 7.2e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIK63231.1 - 4.3e-06 27.3 0.0 7.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK63231.1 - 0.0002 22.0 0.0 0.00055 20.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK63231.1 - 0.00023 20.8 0.0 0.0012 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KIK63231.1 - 0.0052 16.6 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63231.1 - 0.07 13.9 0.0 0.23 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PqqA PF08042.11 KIK63231.1 - 0.18 11.9 0.9 0.72 10.0 0.1 2.2 2 0 0 2 2 2 0 PqqA family Methyltransf_32 PF13679.6 KIK63231.1 - 0.22 11.5 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Citrate_synt PF00285.21 KIK63232.1 - 2.4e-98 329.6 0.0 2.9e-98 329.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KIK63232.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone WD40 PF00400.32 KIK63233.1 - 7e-19 67.8 1.8 9.9e-07 29.4 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK63233.1 - 2.3e-05 24.6 0.1 0.46 10.8 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK63233.1 - 0.0011 17.6 0.2 0.016 13.8 0.2 2.5 3 0 0 3 3 3 1 Cytochrome D1 heme domain BBS2_Mid PF14783.6 KIK63233.1 - 0.028 14.5 0.0 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Complex1_49kDa PF00346.19 KIK63235.1 - 1.8e-120 401.1 0.0 2.3e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KIK63235.1 - 0.0025 16.8 0.0 0.0049 15.8 0.0 1.5 1 0 0 1 1 1 1 Nickel-dependent hydrogenase AKNA PF12443.8 KIK63236.1 - 0.97 10.1 5.3 9.3 7.0 1.7 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor KIF1B PF12423.8 KIK63236.1 - 5.8 7.4 6.1 2.6 8.5 0.5 2.2 2 0 0 2 2 2 0 Kinesin protein 1B Retrotran_gag_3 PF14244.6 KIK63237.1 - 1.9e-07 30.8 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KIK63237.1 - 1e-06 28.5 0.1 1.3e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK63237.1 - 0.0083 15.8 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) CHU_C PF13585.6 KIK63238.1 - 0.041 13.9 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Zn_clus PF00172.18 KIK63240.1 - 0.06 13.5 3.5 2.6 8.3 0.7 2.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S64 PF08192.11 KIK63240.1 - 3.1 6.2 12.7 3.7 5.9 12.7 1.4 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 KIK63240.1 - 6.9 5.2 9.8 6.8 5.2 9.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4201 PF13870.6 KIK63241.1 - 0.02 14.6 2.3 0.02 14.6 2.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF3018 PF11455.8 KIK63241.1 - 0.03 14.2 0.6 0.083 12.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) PEP-utilisers_N PF05524.13 KIK63241.1 - 0.15 12.2 7.4 0.39 10.9 1.7 2.8 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.11 KIK63241.1 - 0.32 9.8 15.8 0.089 11.7 9.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein THOC7 PF05615.13 KIK63241.1 - 0.37 11.1 11.1 0.036 14.3 4.6 2.6 1 1 0 2 2 2 0 Tho complex subunit 7 YlbD_coat PF14071.6 KIK63241.1 - 0.38 11.0 7.1 1.3 9.3 2.4 2.4 1 1 1 2 2 2 0 Putative coat protein FlaC_arch PF05377.11 KIK63241.1 - 0.42 11.0 6.8 1.5 9.3 0.1 4.1 4 2 0 4 4 3 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.18 KIK63241.1 - 0.42 10.7 4.3 5.1 7.2 0.2 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase PEPcase_2 PF14010.6 KIK63241.1 - 0.72 8.3 5.9 0.27 9.7 1.6 1.9 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase Golgin_A5 PF09787.9 KIK63241.1 - 1.4 8.3 17.2 0.076 12.5 10.0 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 KIK63241.1 - 1.5 8.9 18.0 0.37 10.9 6.7 3.1 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.17 KIK63241.1 - 7.7 6.5 11.9 4.6 7.2 0.7 3.4 3 1 0 3 3 3 0 Prefoldin subunit Prefoldin_2 PF01920.20 KIK63241.1 - 9 6.3 22.1 1.9 8.5 0.7 4.4 2 1 1 4 4 4 0 Prefoldin subunit PIF1 PF05970.14 KIK63242.1 - 0.0025 17.0 0.0 0.0031 16.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Pur_ac_phosph_N PF16656.5 KIK63243.1 - 0.056 14.0 0.2 4.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain NTP_transf_4 PF13562.6 KIK63243.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase NRDE-2 PF08424.10 KIK63244.1 - 0.074 12.2 0.2 0.088 11.9 0.2 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Helitron_like_N PF14214.6 KIK63245.1 - 2.6e-12 47.3 0.0 2.8e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_int_SAM_4 PF13495.6 KIK63246.1 - 0.016 15.7 0.1 0.025 15.1 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Peptidase_U32_C PF16325.5 KIK63247.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain zf-CCHC PF00098.23 KIK63248.1 - 1.5e-07 31.1 4.0 2.6e-07 30.4 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KIK63248.1 - 0.00078 19.4 1.8 0.001 19.0 1.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KIK63248.1 - 0.019 14.8 2.3 0.027 14.3 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK63248.1 - 0.035 13.9 4.6 0.047 13.5 4.6 1.3 1 0 0 1 1 1 0 Zinc knuckle GNAT_acetyltr_2 PF13718.6 KIK63249.1 - 0.22 10.9 7.5 0.14 11.6 5.6 1.5 1 1 0 2 2 2 0 GNAT acetyltransferase 2 GAGA_bind PF06217.12 KIK63249.1 - 1.1 9.5 14.6 1.3 9.3 14.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KIK63249.1 - 2 8.2 20.4 2.4 7.9 20.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5427 PF10310.9 KIK63249.1 - 3.4 6.5 22.2 3.8 6.4 22.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) KBP_C PF12309.8 KIK63249.1 - 8.4 5.8 18.1 10 5.5 18.1 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DUF4228 PF14009.6 KIK63249.1 - 9.2 6.6 13.1 11 6.3 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Tma16 PF11176.8 KIK63251.1 - 0.0024 17.7 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Translation machinery-associated protein 16 LigB PF02900.18 KIK63252.1 - 4.9e-17 61.9 0.0 5.9e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase RES PF08808.11 KIK63252.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RES domain FAD_binding_3 PF01494.19 KIK63253.1 - 2.5e-65 221.0 0.0 3.9e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIK63253.1 - 9.6e-11 42.0 0.0 4.8e-10 39.7 0.0 2.0 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KIK63253.1 - 9.4e-05 21.3 0.2 0.00019 20.2 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIK63253.1 - 0.00058 19.2 0.0 0.004 16.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK63253.1 - 0.00083 19.5 0.2 0.004 17.4 0.1 2.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK63253.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK63253.1 - 0.0021 17.7 1.5 0.022 14.3 1.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK63253.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIK63253.1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK63253.1 - 0.0079 15.6 0.4 0.015 14.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK63253.1 - 0.014 14.2 0.0 0.052 12.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KIK63253.1 - 0.046 13.0 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CK2S PF15011.6 KIK63253.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Casein Kinase 2 substrate Pyr_redox PF00070.27 KIK63253.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK63253.1 - 0.092 11.8 1.0 0.23 10.4 0.8 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein YycC PF14174.6 KIK63253.1 - 0.096 12.5 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 YycC-like protein AMP-binding PF00501.28 KIK63254.1 - 6.3e-37 127.2 0.0 1.9e-36 125.6 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK63254.1 - 9.2e-20 70.9 0.0 1.5e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK63254.1 - 3.6e-05 23.4 0.0 6.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK63254.1 - 0.0017 18.7 0.1 0.0048 17.2 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KIK63255.1 - 1.3e-45 155.8 0.3 1.5e-45 155.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK63255.1 - 4.9e-35 120.8 1.2 1.3e-34 119.4 1.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK63255.1 - 0.00021 21.3 0.2 0.00037 20.5 0.2 1.5 1 1 0 1 1 1 1 KR domain Dabb PF07876.12 KIK63256.1 - 5.8e-13 49.3 0.0 6.3e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldedh PF00171.22 KIK63257.1 - 2.9e-08 32.7 0.0 0.001 17.7 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family PCRF PF03462.18 KIK63258.1 - 0.073 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 PCRF domain cNMP_binding PF00027.29 KIK63261.1 - 0.024 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Aldedh PF00171.22 KIK63263.1 - 8.2e-11 41.1 0.7 1e-10 40.7 0.7 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TIM PF00121.18 KIK63264.1 - 2.5e-92 308.6 0.0 2.9e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CobU PF02283.16 KIK63264.1 - 0.052 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CutC PF03932.14 KIK63264.1 - 0.096 12.1 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 CutC family ABC_membrane PF00664.23 KIK63265.1 - 7.6e-60 202.9 32.3 1.2e-34 120.2 13.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK63265.1 - 4.2e-53 179.5 0.0 8.1e-28 97.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK63265.1 - 4.3e-09 36.1 3.0 0.027 13.9 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIK63265.1 - 4.9e-07 29.8 3.6 0.0031 17.6 0.1 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK63265.1 - 1.5e-06 27.8 0.1 0.091 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK63265.1 - 4.2e-06 27.2 0.1 0.037 14.4 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK63265.1 - 1e-05 25.5 1.2 0.15 12.0 0.1 2.8 3 0 0 3 3 2 2 RsgA GTPase Dynamin_N PF00350.23 KIK63265.1 - 2.2e-05 24.6 4.2 0.018 15.1 0.0 3.4 4 0 0 4 4 2 2 Dynamin family Zeta_toxin PF06414.12 KIK63265.1 - 3.6e-05 23.1 0.3 0.22 10.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 KIK63265.1 - 9.2e-05 22.4 0.1 0.095 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TrwB_AAD_bind PF10412.9 KIK63265.1 - 9.6e-05 21.4 0.7 0.051 12.5 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 KIK63265.1 - 9.8e-05 21.6 0.4 0.02 14.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KIK63265.1 - 0.00035 20.0 1.1 0.15 11.4 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KIK63265.1 - 0.00059 20.1 0.3 1.7 8.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIK63265.1 - 0.0019 18.7 0.7 2.7 8.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KIK63265.1 - 0.0021 17.1 0.8 0.46 9.4 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KIK63265.1 - 0.0038 17.4 0.2 3.3 7.9 0.1 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KIK63265.1 - 0.0064 16.2 1.3 0.75 9.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK63265.1 - 0.013 15.1 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KIK63265.1 - 0.018 14.6 1.1 2.8 7.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KIK63265.1 - 0.029 14.3 0.8 6.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KIK63265.1 - 0.032 14.7 0.2 9.4 6.7 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 KIK63265.1 - 0.04 13.6 0.3 7 6.2 0.0 2.7 2 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KIK63265.1 - 0.054 13.1 0.0 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK63265.1 - 0.062 12.3 0.0 4.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KIK63265.1 - 0.096 12.5 0.3 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KIK63265.1 - 0.12 12.4 0.1 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tafi-CsgC PF10610.9 KIK63265.1 - 0.17 12.1 0.0 6.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Thin aggregative fimbriae synthesis protein RNA_helicase PF00910.22 KIK63265.1 - 0.17 12.3 0.0 14 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KIK63265.1 - 0.21 11.7 8.5 0.44 10.6 0.1 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KIK63265.1 - 0.27 11.7 0.0 0.27 11.7 0.0 4.5 4 1 1 5 5 4 0 AAA domain NTPase_1 PF03266.15 KIK63265.1 - 0.3 11.0 2.3 11 5.9 0.0 3.5 4 0 0 4 4 4 0 NTPase AAA_15 PF13175.6 KIK63265.1 - 2.2 7.9 11.5 1.3 8.6 0.2 3.6 3 1 0 3 3 3 0 AAA ATPase domain zf-RING_2 PF13639.6 KIK63266.1 - 9.7e-07 29.0 12.0 1.8e-06 28.2 12.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK63266.1 - 8.8e-06 25.5 11.1 1.6e-05 24.7 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK63266.1 - 2.5e-05 24.0 9.5 4.7e-05 23.2 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK63266.1 - 0.0001 22.2 10.9 0.00018 21.4 10.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK63266.1 - 0.0005 20.0 6.8 0.0042 17.1 4.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK63266.1 - 0.00077 19.3 10.9 0.0016 18.3 10.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KIK63266.1 - 0.0054 16.7 3.5 0.0054 16.7 3.5 1.9 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) AAA_11 PF13086.6 KIK63266.1 - 0.031 14.1 0.3 0.044 13.6 0.3 1.3 1 0 0 1 1 1 0 AAA domain SOGA PF11365.8 KIK63266.1 - 0.042 15.0 5.9 0.058 14.5 1.4 2.6 2 1 0 2 2 2 0 Protein SOGA zf-RING_4 PF14570.6 KIK63266.1 - 0.065 13.0 7.4 0.13 12.0 7.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIK63266.1 - 0.066 13.4 11.8 0.12 12.5 11.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK63266.1 - 0.12 12.2 11.2 0.25 11.2 11.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAT PF03417.16 KIK63266.1 - 0.15 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase zf-RING_10 PF16685.5 KIK63266.1 - 0.16 12.1 6.4 0.35 11.0 6.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Syntaxin PF00804.25 KIK63266.1 - 0.21 11.3 4.0 0.29 10.8 3.4 1.5 1 1 0 1 1 1 0 Syntaxin FYVE PF01363.21 KIK63266.1 - 0.26 11.5 12.8 0.3 11.2 10.4 2.2 2 1 1 3 3 2 0 FYVE zinc finger DUF2115 PF09888.9 KIK63266.1 - 0.33 11.5 1.7 17 5.9 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Nsp1_C PF05064.13 KIK63266.1 - 0.82 9.5 4.0 11 5.8 0.9 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region Phage_Mu_Gam PF07352.12 KIK63266.1 - 1.3 8.9 4.2 0.47 10.4 1.0 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ADIP PF11559.8 KIK63266.1 - 1.5 8.9 8.8 0.3 11.2 4.3 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DMPK_coil PF08826.10 KIK63266.1 - 2.5 8.3 9.5 2.4 8.3 2.6 3.0 2 1 1 3 3 3 0 DMPK coiled coil domain like DUF4404 PF14357.6 KIK63266.1 - 2.8 8.6 6.2 1.6 9.5 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Zn_ribbon_17 PF17120.5 KIK63266.1 - 5.2 6.8 8.5 14 5.4 7.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MFS_1 PF07690.16 KIK63267.1 - 1.5e-37 129.4 41.6 2.3e-37 128.7 41.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK63267.1 - 3.7e-14 52.1 13.6 6.7e-14 51.2 13.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFR_dimer PF04253.15 KIK63268.1 - 4.7e-22 78.4 0.2 7.1e-20 71.3 0.0 2.6 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIK63268.1 - 6.4e-14 52.1 0.1 2.5e-13 50.2 0.1 2.0 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KIK63268.1 - 5.4e-11 42.4 0.5 3.6e-10 39.7 0.5 2.2 1 1 0 1 1 1 1 PA domain Beach PF02138.18 KIK63270.1 - 1.3e-108 362.5 0.0 2.5e-108 361.6 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KIK63270.1 - 1.8e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KIK63270.1 - 1.1e-06 29.3 2.2 0.036 14.9 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4704 PF15787.5 KIK63270.1 - 0.058 12.6 1.2 0.21 10.8 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4704) dCMP_cyt_deam_1 PF00383.23 KIK63272.1 - 7.7e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK63272.1 - 9.6e-09 35.1 0.1 3e-08 33.5 0.0 1.8 1 1 0 2 2 2 1 MafB19-like deaminase Prenyltrans PF00432.21 KIK63275.1 - 0.13 12.0 0.8 2.3 8.0 0.1 3.1 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat NTP_transf_2 PF01909.23 KIK63276.1 - 7.3e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KIK63276.1 - 1.3e-05 25.3 0.1 3.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.6 KIK63276.1 - 0.054 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Epimerase PF01370.21 KIK63277.1 - 3.4e-15 56.2 0.0 5.6e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK63277.1 - 5.9e-14 52.4 0.1 1.3e-13 51.3 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK63277.1 - 7.4e-13 48.1 0.0 1.1e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KIK63277.1 - 1.9e-08 34.1 0.7 3.6e-08 33.2 0.6 1.5 1 1 1 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIK63277.1 - 8.9e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK63277.1 - 2.6e-05 23.5 0.0 0.00017 20.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KIK63277.1 - 0.00088 18.8 0.0 0.0016 17.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK63277.1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KIK63277.1 - 0.057 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIK63277.1 - 0.077 12.1 0.8 0.3 10.2 0.8 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DSL PF01414.19 KIK63278.1 - 0.058 13.7 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 Delta serrate ligand Babuvirus_MP PF07234.11 KIK63278.1 - 1.3 9.2 6.3 0.14 12.4 0.9 2.0 1 1 1 2 2 2 0 Movement and RNA silencing protein PAP_assoc PF03828.19 KIK63281.1 - 0.00032 20.9 0.9 0.00046 20.3 0.0 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIK63281.1 - 0.0022 18.3 0.0 1.4 9.2 0.0 2.5 2 1 0 2 2 2 2 Nucleotidyltransferase domain WD40 PF00400.32 KIK63282.1 - 1.3e-06 29.0 0.7 0.059 14.3 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 KIK63282.1 - 0.00037 20.3 2.7 0.00048 19.9 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK63282.1 - 0.0011 18.8 3.6 0.0039 17.0 0.8 2.5 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KIK63282.1 - 0.14 12.4 0.1 44 4.5 0.0 3.3 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_25 PF01183.20 KIK63283.1 - 8.4e-50 169.4 0.1 9.7e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_25 PF01183.20 KIK63284.1 - 6.3e-24 85.1 0.0 6.6e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_25 PF01183.20 KIK63285.1 - 2.4e-47 161.4 0.0 2.7e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_25 PF01183.20 KIK63286.1 - 2.1e-47 161.6 0.0 2.4e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 zf-TFIIIC PF12660.7 KIK63290.1 - 7.3e-22 77.2 0.4 1.5e-21 76.2 0.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 KIK63290.1 - 3.5e-16 59.7 1.6 6.7e-16 58.8 1.6 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term RRM_1 PF00076.22 KIK63291.1 - 1.2e-59 198.0 0.0 3.4e-14 52.4 0.0 6.9 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK63291.1 - 3.7e-09 36.6 0.0 0.033 14.3 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif RRM_Rrp7 PF17799.1 KIK63291.1 - 5e-05 23.1 0.0 3.9 7.3 0.0 4.0 3 0 0 3 3 3 3 Rrp7 RRM-like N-terminal domain Aldo_ket_red PF00248.21 KIK63292.1 - 2.4e-46 158.3 0.0 6.3e-38 130.6 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family DUF2774 PF11242.8 KIK63292.1 - 0.23 11.7 0.6 1.5 9.0 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) PspA_IM30 PF04012.12 KIK63293.1 - 0.001 18.7 4.8 0.0041 16.7 4.8 1.8 1 1 0 1 1 1 1 PspA/IM30 family Phage_Mu_Gam PF07352.12 KIK63293.1 - 0.013 15.4 0.8 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Cortex-I_coil PF09304.10 KIK63293.1 - 0.051 13.8 4.2 0.082 13.1 4.2 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF5501 PF17605.2 KIK63293.1 - 0.25 11.8 0.3 0.25 11.8 0.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5501) POX PF07526.11 KIK63293.1 - 0.36 11.4 3.1 0.87 10.2 3.1 1.8 1 1 0 1 1 1 0 Associated with HOX Syntaxin-6_N PF09177.11 KIK63293.1 - 0.4 11.3 5.0 2.2 8.9 4.9 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Endonuc_Holl PF10107.9 KIK63293.1 - 0.42 10.5 4.6 7.1 6.5 0.4 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Cep57_CLD_2 PF14197.6 KIK63293.1 - 1.1 9.4 9.5 14 5.9 0.3 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Pkinase PF00069.25 KIK63296.1 - 3.9e-37 128.1 0.0 1e-36 126.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63296.1 - 8.3e-13 48.2 0.0 2.1e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK63296.1 - 0.00038 20.5 0.1 0.0056 16.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK63296.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 KIK63297.1 - 9.4e-06 25.4 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK63297.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIK63297.1 - 0.0052 16.8 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KIK63297.1 - 0.024 14.5 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pyr_redox_2 PF07992.14 KIK63298.1 - 1.4e-66 224.7 8.1 1.4e-66 224.7 8.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIK63298.1 - 2.2e-43 147.0 1.1 2.1e-42 143.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIK63298.1 - 1.1e-21 77.2 12.1 1.7e-19 70.1 2.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK63298.1 - 8.2e-12 44.9 1.0 8.2e-12 44.9 1.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIK63298.1 - 4.5e-11 42.6 6.6 1.3e-07 31.2 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK63298.1 - 6.6e-11 42.2 0.1 6.6e-11 42.2 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK63298.1 - 1.2e-09 38.3 3.2 4.5e-05 23.6 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK63298.1 - 1e-06 27.7 14.4 0.0002 20.2 1.0 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 KIK63298.1 - 2.3e-06 27.0 2.4 2.3e-06 27.0 2.4 3.6 3 1 1 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIK63298.1 - 2.4e-06 27.0 4.5 0.012 14.9 0.6 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KIK63298.1 - 2.8e-06 26.7 2.4 0.041 13.0 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KIK63298.1 - 5.1e-05 22.7 12.6 0.0056 16.0 1.2 3.5 3 1 0 3 3 3 3 FAD binding domain THF_DHG_CYH_C PF02882.19 KIK63298.1 - 0.00042 19.7 2.7 0.0012 18.2 0.4 2.7 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Thi4 PF01946.17 KIK63298.1 - 0.00045 19.5 3.1 0.0032 16.8 0.1 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK63298.1 - 0.0039 16.8 17.9 0.35 10.4 0.3 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIK63298.1 - 0.048 13.0 0.7 0.12 11.6 0.7 1.6 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KIK63298.1 - 0.33 10.8 4.8 0.31 10.9 1.4 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIK63298.1 - 0.89 10.0 6.2 6.5 7.3 1.8 3.4 3 1 0 3 3 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KIK63298.1 - 8.4 6.4 9.6 18 5.3 0.2 3.5 4 0 0 4 4 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK63298.1 - 9.4 5.2 9.9 2.2 7.2 1.1 3.3 3 1 0 3 3 3 0 Lycopene cyclase protein Methyltransf_2 PF00891.18 KIK63299.1 - 5.4e-25 87.9 0.0 4.1e-22 78.5 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KIK63299.1 - 0.0039 17.9 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK63299.1 - 0.008 16.0 0.0 0.024 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63299.1 - 0.024 15.4 0.0 0.077 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Nup153 PF08604.10 KIK63300.1 - 0.024 13.5 0.5 0.03 13.1 0.5 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like CadC_C1 PF18500.1 KIK63300.1 - 0.17 12.0 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 CadC C-terminal domain 1 F-box PF00646.33 KIK63301.1 - 0.035 14.0 0.0 0.9 9.5 0.0 2.6 2 0 0 2 2 2 0 F-box domain FERM_C PF09380.10 KIK63301.1 - 0.091 13.2 0.0 13 6.2 0.0 3.0 3 0 0 3 3 3 0 FERM C-terminal PH-like domain Sterol-sensing PF12349.8 KIK63302.1 - 0.16 11.8 0.3 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Snapin_Pallidin PF14712.6 KIK63307.1 - 0.036 14.5 1.0 0.036 14.5 1.0 3.3 2 1 0 2 2 2 0 Snapin/Pallidin GBR2_CC PF18455.1 KIK63307.1 - 0.11 12.6 3.3 0.41 10.8 0.0 3.3 4 0 0 4 4 4 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain NBD_C PF17042.5 KIK63307.1 - 2.5 8.6 10.0 4.2 7.9 1.0 2.9 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain KxDL PF10241.9 KIK63307.1 - 3.1 8.1 12.8 9.7 6.6 0.6 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.9 KIK63307.1 - 4.3 6.3 29.7 1.7 7.7 12.7 3.1 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin-6_N PF09177.11 KIK63307.1 - 4.4 7.9 20.9 0.16 12.5 0.4 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF5345 PF17280.2 KIK63307.1 - 7.3 6.7 8.4 3.1 7.8 2.9 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) AAA_12 PF13087.6 KIK63308.1 - 2.6e-35 121.9 0.0 4.6e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK63308.1 - 6.3e-30 104.8 0.1 1.9e-28 100.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK63308.1 - 1.4e-10 41.2 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK63308.1 - 4.8e-09 36.7 0.1 1.4e-07 31.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain zf-CCCH_4 PF18044.1 KIK63308.1 - 0.00042 20.0 3.2 0.00042 20.0 3.2 3.9 4 0 0 4 4 4 2 CCCH-type zinc finger AAA_5 PF07728.14 KIK63308.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK63308.1 - 0.0088 16.3 0.0 0.047 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIK63308.1 - 0.018 14.3 0.0 3.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KIK63308.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain zf_CCCH_4 PF18345.1 KIK63308.1 - 0.048 13.7 16.5 0.21 11.7 2.1 2.9 2 0 0 2 2 2 0 Zinc finger domain UvrD-helicase PF00580.21 KIK63308.1 - 0.055 13.0 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KIK63308.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KIK63308.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KIK63308.1 - 0.17 12.3 0.0 0.71 10.3 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KIK63309.1 - 3.3e-33 115.0 0.0 6.6e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK63309.1 - 4.9e-27 95.4 0.4 2.5e-25 89.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK63309.1 - 8.9e-11 41.9 0.0 8.4e-07 28.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KIK63309.1 - 1.4e-09 38.5 0.1 3.9e-08 33.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK63309.1 - 0.00077 18.8 0.2 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KIK63309.1 - 0.0034 16.7 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 KaiC UvrD_C_2 PF13538.6 KIK63309.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain zf_CCCH_4 PF18345.1 KIK63309.1 - 0.03 14.4 13.6 0.25 11.4 2.1 3.0 2 0 0 2 2 2 0 Zinc finger domain AAA_5 PF07728.14 KIK63309.1 - 0.08 12.9 0.1 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 KIK63309.1 - 0.083 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KIK63309.1 - 0.12 12.8 0.1 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain CLZ PF16526.5 KIK63309.1 - 0.22 11.9 1.0 23 5.4 0.3 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 KIK63309.1 - 0.68 10.0 3.9 19 5.3 0.1 4.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.25 KIK63310.1 - 4.2e-11 42.7 0.0 1.3e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK63310.1 - 4e-06 26.9 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK63310.1 - 7e-06 25.8 0.1 1.2e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KIK63310.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 KIK63310.1 - 0.13 12.7 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Rz1 PF06085.11 KIK63311.1 - 0.3 10.9 2.5 0.64 9.8 2.5 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor TPR_12 PF13424.6 KIK63313.1 - 1.6e-30 105.2 23.0 6.5e-07 29.6 0.1 6.8 2 1 7 9 9 9 8 Tetratricopeptide repeat SNAP PF14938.6 KIK63313.1 - 7.7e-15 55.1 5.9 1.6e-07 31.1 0.1 3.2 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KIK63313.1 - 1.5e-11 44.2 7.9 2e-06 27.4 0.4 2.3 1 1 1 2 2 2 2 MalT-like TPR region NACHT PF05729.12 KIK63313.1 - 1.1e-09 38.5 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SHNi-TPR PF10516.9 KIK63313.1 - 2.4e-09 36.5 0.0 2.5 7.6 0.0 6.3 7 0 0 7 7 7 3 SHNi-TPR TPR_2 PF07719.17 KIK63313.1 - 9.9e-09 34.7 17.2 0.31 11.3 0.2 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat AAA_16 PF13191.6 KIK63313.1 - 7.7e-08 32.9 0.1 2.6e-06 27.9 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK63313.1 - 1.9e-06 27.3 0.0 5.5e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK63313.1 - 7e-06 26.4 0.0 2.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.6 KIK63313.1 - 2.2e-05 24.1 15.2 0.41 10.6 0.2 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK63313.1 - 0.00081 19.1 9.3 0.81 9.6 0.4 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KIK63313.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 KIK63313.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein TPR_3 PF07720.12 KIK63313.1 - 0.12 12.4 0.5 0.88 9.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK63313.1 - 0.38 11.4 3.7 3.4 8.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4298 PF14131.6 KIK63313.1 - 0.66 10.0 7.0 24 5.0 0.0 5.3 6 1 0 6 6 5 0 Domain of unknown function (DUF4298) TPR_6 PF13174.6 KIK63313.1 - 0.67 10.7 12.7 13 6.7 0.0 7.5 6 3 1 7 7 6 0 Tetratricopeptide repeat YMF19 PF02326.15 KIK63316.1 - 0.06 14.1 0.0 0.078 13.8 0.0 1.2 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF2367 PF10164.9 KIK63316.1 - 0.28 11.7 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) AAA_16 PF13191.6 KIK63317.1 - 0.044 14.2 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KIK63317.1 - 0.21 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein TPR_10 PF13374.6 KIK63318.1 - 7.8e-247 791.8 22.2 1.3e-14 53.5 0.1 20.0 20 0 0 20 20 20 18 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63318.1 - 3.7e-175 568.6 56.3 5.2e-17 61.9 0.1 16.9 3 2 15 18 18 18 17 Tetratricopeptide repeat TPR_8 PF13181.6 KIK63318.1 - 3.4e-65 210.9 49.9 0.00033 20.6 0.0 17.3 17 0 0 17 17 17 17 Tetratricopeptide repeat TPR_7 PF13176.6 KIK63318.1 - 7.8e-51 166.4 32.7 0.037 14.0 0.0 17.5 17 0 0 17 17 17 16 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK63318.1 - 2.1e-43 149.0 16.4 1.5e-08 34.4 1.0 7.4 1 1 4 6 6 6 6 MalT-like TPR region TPR_1 PF00515.28 KIK63318.1 - 2.2e-37 125.3 38.2 0.61 10.0 0.1 17.5 17 0 0 17 17 17 16 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63318.1 - 2.5e-25 86.5 34.7 0.74 10.1 0.1 16.9 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK63318.1 - 1.7e-21 75.0 46.9 1.5 9.4 0.1 17.2 18 0 0 18 18 18 7 Tetratricopeptide repeat TPR_19 PF14559.6 KIK63318.1 - 1.3e-17 64.1 18.4 7 7.2 0.0 15.4 4 2 12 17 17 17 1 Tetratricopeptide repeat DUF1897 PF09005.10 KIK63318.1 - 4.2e-11 42.1 5.8 43 3.7 0.0 13.1 16 0 0 16 16 16 0 Domain of unknown function (DUF1897) DUF4919 PF16266.5 KIK63318.1 - 3.4e-10 40.2 23.0 2.9 7.8 0.1 10.8 2 2 12 15 15 15 3 Domain of unknown function (DUF4919) TPR_14 PF13428.6 KIK63318.1 - 2.8e-05 24.6 20.3 5.7 8.0 0.0 12.9 16 0 0 16 16 16 1 Tetratricopeptide repeat Trans_reg_C PF00486.28 KIK63318.1 - 0.00026 21.0 0.0 25 5.1 0.0 5.3 5 1 1 6 6 6 0 Transcriptional regulatory protein, C terminal Phosphatase PF15698.5 KIK63318.1 - 0.0017 17.6 1.3 13 4.8 0.0 4.9 2 2 2 6 6 6 0 Phosphatase PPR_long PF17177.4 KIK63318.1 - 0.79 9.0 6.7 50 3.2 0.0 5.5 2 2 3 8 8 8 0 Pentacotripeptide-repeat region of PRORP PBP1_TM PF14812.6 KIK63320.1 - 7.4 7.0 7.6 3.2 8.2 0.4 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_10 PF13374.6 KIK63323.1 - 4.4e-165 531.9 3.7 6.9e-15 54.4 0.0 12.1 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63323.1 - 7.2e-110 359.4 28.2 1.4e-12 47.7 0.2 10.9 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_8 PF13181.6 KIK63323.1 - 2.4e-45 148.9 28.1 0.00028 20.8 0.1 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.6 KIK63323.1 - 9.6e-35 116.1 17.6 0.033 14.2 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 KIK63323.1 - 4.6e-28 95.9 21.5 0.11 12.4 0.1 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK63323.1 - 6.4e-26 91.5 18.3 5e-10 39.3 1.5 4.2 1 1 3 4 4 4 4 MalT-like TPR region TPR_2 PF07719.17 KIK63323.1 - 3.2e-22 76.8 17.3 0.091 12.9 0.1 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK63323.1 - 3.7e-16 59.4 6.6 0.41 11.2 0.0 9.9 1 1 9 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK63323.1 - 9.6e-15 53.8 23.0 0.58 10.7 0.0 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat DUF4919 PF16266.5 KIK63323.1 - 8.9e-11 42.1 7.6 0.84 9.6 0.1 6.7 2 2 3 7 7 7 5 Domain of unknown function (DUF4919) TPR_16 PF13432.6 KIK63323.1 - 2.5e-08 34.4 3.6 11 6.8 0.2 9.0 5 3 5 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK63323.1 - 2.7e-08 33.7 0.0 32 5.6 0.0 8.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK63323.1 - 2.6e-07 30.9 4.5 61 4.8 0.0 8.9 10 0 0 10 10 9 0 Tetratricopeptide repeat Fibritin_C PF07921.12 KIK63323.1 - 6.3e-07 29.4 0.2 36 4.6 0.0 8.3 5 3 5 10 10 9 0 Fibritin C-terminal region HHH_3 PF12836.7 KIK63323.1 - 0.00011 22.3 3.7 18 5.6 0.0 7.7 9 0 0 9 9 9 0 Helix-hairpin-helix motif Na_H_antiport_2 PF13726.6 KIK63323.1 - 0.00069 19.7 1.6 70 3.6 0.0 7.6 9 1 0 10 10 10 0 Na+-H+ antiporter family Bac_export_3 PF01313.19 KIK63323.1 - 0.00083 19.2 0.0 1.4e+02 2.5 0.0 6.8 9 0 0 9 9 9 0 Bacterial export proteins, family 3 UPF0489 PF12640.7 KIK63323.1 - 0.0047 17.2 1.5 69 3.6 0.1 5.5 2 2 3 5 5 5 0 UPF0489 domain Peptidase_S28 PF05577.12 KIK63323.1 - 0.0055 15.5 0.4 5 5.8 0.0 3.8 1 1 1 3 3 3 1 Serine carboxypeptidase S28 MCPVI PF02993.14 KIK63323.1 - 0.014 15.2 2.7 46 3.7 0.0 5.8 1 1 6 7 7 7 0 Minor capsid protein VI Haem_degrading PF03928.14 KIK63323.1 - 0.038 14.1 0.2 31 4.6 0.0 4.0 5 0 0 5 5 5 0 Haem-degrading DUF5619 PF18505.1 KIK63323.1 - 0.05 13.6 0.3 6.1 6.9 0.1 3.6 3 1 0 4 4 3 0 Domain of unknown function (DUF5619) DCAF17 PF15802.5 KIK63323.1 - 0.095 11.4 0.0 5.2 5.6 0.0 3.3 3 1 1 4 4 4 0 DDB1- and CUL4-associated factor 17 Gly_rich PF12810.7 KIK63326.1 - 1.9 8.3 13.0 23 4.8 13.0 2.1 1 1 0 1 1 1 0 Glycine rich protein NAD_binding_8 PF13450.6 KIK63326.1 - 6.7 7.0 8.4 11 6.3 0.2 4.3 1 1 3 5 5 5 0 NAD(P)-binding Rossmann-like domain RAP1 PF07218.11 KIK63330.1 - 8.3 4.6 8.2 9.9 4.3 8.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Stanniocalcin PF03298.13 KIK63333.1 - 0.0039 16.5 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Stanniocalcin family zf-C2H2 PF00096.26 KIK63334.1 - 1.4e-10 41.0 3.3 1.1e-05 25.6 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK63334.1 - 5.4e-09 36.1 3.5 9.5e-05 22.9 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK63334.1 - 1.2e-05 25.5 8.7 0.0024 18.2 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK63334.1 - 0.0017 18.6 0.2 0.0041 17.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIK63334.1 - 0.021 14.7 2.4 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIK63334.1 - 0.023 15.0 0.3 0.041 14.2 0.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KIK63334.1 - 0.042 13.9 2.0 0.09 12.8 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 KIK63334.1 - 0.5 10.4 3.0 0.4 10.7 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger ARS2 PF04959.13 KIK63334.1 - 3.9 7.8 11.1 12 6.3 3.3 3.1 2 1 1 3 3 3 0 Arsenite-resistance protein 2 Pkinase PF00069.25 KIK63335.1 - 9e-72 241.6 0.0 1.2e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63335.1 - 4.3e-38 131.1 0.0 7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KIK63335.1 - 5.6e-18 65.5 0.3 4.9e-09 36.7 0.0 3.4 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KIK63335.1 - 6.7e-07 29.3 0.4 1.4e-06 28.3 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Haspin_kinase PF12330.8 KIK63335.1 - 2.2e-05 23.6 0.1 3.2e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK63335.1 - 2.9e-05 23.5 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK63335.1 - 0.0001 22.0 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK63335.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK63335.1 - 0.066 13.1 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 KIK63335.1 - 0.11 11.2 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_L3_FP4 PF03339.14 KIK63336.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein Claudin_2 PF13903.6 KIK63336.1 - 1 9.1 6.1 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Oxidored_FMN PF00724.20 KIK63337.1 - 7.8e-69 232.5 0.0 9.3e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIK63337.1 - 0.0002 20.5 0.0 0.00054 19.2 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Peptidase_C14 PF00656.22 KIK63339.1 - 4.4e-15 56.3 0.0 6.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain TPR_10 PF13374.6 KIK63340.1 - 6.8e-45 149.8 15.9 0.0073 16.2 0.0 19.3 20 0 0 20 20 20 10 Tetratricopeptide repeat CHAT PF12770.7 KIK63340.1 - 9.6e-39 133.5 0.0 1.9e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KIK63340.1 - 2.9e-23 80.1 20.8 1.3 9.4 0.0 18.4 20 2 0 20 20 18 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63340.1 - 4e-19 68.7 25.2 1.3 9.4 0.7 16.7 8 5 12 20 20 19 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63340.1 - 2e-12 46.2 40.0 2.8 8.3 0.3 19.6 21 3 2 23 23 19 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK63340.1 - 5.1e-12 45.3 44.4 1.6 8.5 0.1 17.9 18 3 0 18 18 18 2 TPR repeat PG_binding_1 PF01471.18 KIK63340.1 - 1.5e-10 41.1 1.6 1.2 9.4 0.0 9.3 11 1 0 11 11 9 2 Putative peptidoglycan binding domain TPR_7 PF13176.6 KIK63340.1 - 1.1e-05 25.1 11.9 0.98 9.6 0.0 11.4 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK63340.1 - 0.00017 21.3 48.2 0.96 9.4 0.0 18.9 21 2 1 22 22 21 1 Tetratricopeptide repeat P22_Cro PF14549.6 KIK63340.1 - 0.0019 18.0 0.0 0.46 10.4 0.0 3.0 2 0 0 2 2 2 1 DNA-binding transcriptional regulator Cro HSBP1 PF06825.12 KIK63340.1 - 0.0024 17.7 4.0 10 6.0 0.0 6.7 7 0 0 7 7 7 0 Heat shock factor binding protein 1 TPR_17 PF13431.6 KIK63340.1 - 0.0032 17.7 16.6 0.46 11.0 0.0 7.9 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIK63340.1 - 0.0033 17.5 14.7 21 5.4 0.0 8.9 11 1 0 11 11 11 0 Tetratricopeptide repeat DUF5588 PF17826.1 KIK63340.1 - 0.0048 15.8 2.4 4.8 6.0 0.0 4.6 4 1 1 5 5 5 1 Family of unknown function (DUF5588) TPR_14 PF13428.6 KIK63340.1 - 0.0056 17.4 16.6 1.3e+02 3.8 0.0 11.0 14 0 0 14 14 9 0 Tetratricopeptide repeat PH_11 PF15413.6 KIK63340.1 - 0.0072 16.7 0.2 8.6 6.8 0.0 4.7 5 0 0 5 5 5 0 Pleckstrin homology domain PhageMin_Tail PF10145.9 KIK63340.1 - 0.05 13.5 2.5 0.54 10.1 0.0 3.4 3 0 0 3 3 3 0 Phage-related minor tail protein Retrotrans_gag PF03732.17 KIK63340.1 - 0.079 13.2 2.3 10 6.5 0.0 4.8 5 0 0 5 5 3 0 Retrotransposon gag protein POTRA_3 PF17287.2 KIK63340.1 - 0.081 12.4 2.1 1.2 8.7 0.0 4.2 4 0 0 4 4 4 0 POTRA domain EzrA PF06160.12 KIK63340.1 - 0.083 11.0 1.2 5.4 5.1 0.1 3.8 4 0 0 4 4 4 0 Septation ring formation regulator, EzrA Strumpellin PF10266.9 KIK63340.1 - 0.43 8.2 1.9 0.69 7.5 0.2 2.1 2 1 0 3 3 3 0 Hereditary spastic paraplegia protein strumpellin SOAR PF16533.5 KIK63340.1 - 0.68 9.9 4.5 5 7.1 0.1 4.8 6 0 0 6 6 3 0 STIM1 Orai1-activating region Erythro-docking PF09277.11 KIK63340.1 - 0.71 9.8 18.4 7.4 6.6 0.2 8.4 10 0 0 10 10 9 0 Erythronolide synthase, docking RNA_lig_T4_1 PF09511.10 KIK63344.1 - 3.2e-16 59.8 0.0 3.1e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 RNA ligase PHM7_cyt PF14703.6 KIK63345.1 - 0.043 14.0 9.6 0.048 13.9 9.6 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF3450 PF11932.8 KIK63345.1 - 0.15 11.4 10.1 0.18 11.1 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tropomyosin PF00261.20 KIK63345.1 - 0.21 10.9 21.9 0.23 10.8 21.9 1.0 1 0 0 1 1 1 0 Tropomyosin APG6_N PF17675.1 KIK63345.1 - 0.31 11.6 19.6 0.55 10.8 19.6 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KIK63345.1 - 0.45 9.3 18.1 0.47 9.3 18.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMP_2 PF06791.13 KIK63345.1 - 0.48 10.1 5.3 0.09 12.4 1.2 1.8 1 1 1 2 2 2 0 Prophage tail length tape measure protein Fib_alpha PF08702.10 KIK63345.1 - 1.7 8.8 7.6 2.1 8.5 7.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CC2-LZ PF16516.5 KIK63345.1 - 1.8 9.0 15.2 1.1 9.6 5.7 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Neugrin PF06413.11 KIK63345.1 - 2.6 8.0 11.0 3 7.8 11.0 1.0 1 0 0 1 1 1 0 Neugrin AAA_13 PF13166.6 KIK63345.1 - 3.7 6.1 17.2 4.1 5.9 17.2 1.1 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.9 KIK63345.1 - 4.3 6.1 12.6 4.9 5.9 12.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 KIK63345.1 - 8.1 5.6 11.1 9.6 5.3 11.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 KIK63345.1 - 8.9 6.7 15.9 16 5.8 15.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LprI PF07007.12 KIK63345.1 - 9.5 6.9 10.7 8.5 7.1 3.0 2.1 1 1 1 2 2 2 0 Lysozyme inhibitor LprI Cytochrom_B561 PF03188.16 KIK63346.1 - 1.2e-11 44.9 4.0 1.8e-11 44.3 4.0 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2781 PF10914.8 KIK63346.1 - 0.38 11.1 6.9 1.1 9.6 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) DIOX_N PF14226.6 KIK63348.1 - 2.2e-19 70.4 0.1 3.9e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK63348.1 - 1e-13 51.6 0.0 2.7e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4227 PF14004.6 KIK63348.1 - 0.059 13.3 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) ketoacyl-synt PF00109.26 KIK63350.1 - 7.5e-55 186.3 3.1 1e-54 185.8 0.5 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK63350.1 - 8.5e-34 117.5 0.0 1.6e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIK63350.1 - 1.6e-31 109.6 0.1 3.4e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KIK63350.1 - 1.3e-29 102.6 0.2 2.9e-29 101.5 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIK63350.1 - 5.7e-23 81.6 0.0 1.3e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KIK63350.1 - 3.4e-19 69.9 0.2 1.2e-18 68.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 KIK63350.1 - 1e-14 54.9 0.0 4.2e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIK63350.1 - 8.7e-11 42.0 0.1 1.9e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KIK63350.1 - 1.2e-07 31.8 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KIK63350.1 - 1.9e-06 27.5 0.1 6.1e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KIK63350.1 - 9.1e-06 25.2 0.7 0.0002 20.8 0.1 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.12 KIK63350.1 - 7e-05 23.5 0.0 0.00018 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK63350.1 - 0.00026 21.6 0.0 0.00079 20.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.10 KIK63350.1 - 0.0029 17.4 2.7 0.057 13.3 2.7 2.8 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Benyvirus_P25 PF05744.11 KIK63350.1 - 0.02 14.2 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Methyltransf_31 PF13847.6 KIK63350.1 - 0.024 14.4 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RPE65 PF03055.15 KIK63352.1 - 1.1e-110 371.0 0.0 1.4e-110 370.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zip PF02535.22 KIK63353.1 - 1.9e-61 208.2 14.8 2.2e-61 207.9 14.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.25 KIK63355.1 - 7.2e-52 176.3 0.0 6.8e-31 107.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63355.1 - 9.9e-19 67.6 0.0 3.7e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK63355.1 - 1.3e-09 37.8 0.0 0.0017 17.8 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KIK63355.1 - 1.6e-05 23.9 0.0 2.7e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KIK63355.1 - 0.0037 16.9 0.1 0.025 14.2 0.0 1.9 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 KIK63355.1 - 0.0084 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK63355.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family KDZ PF18758.1 KIK63357.1 - 3.3e-31 108.6 0.9 1.9e-30 106.2 0.9 1.9 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase BHD_1 PF10403.9 KIK63357.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 DUF4462 PF14692.6 KIK63357.1 - 2.4 7.7 4.2 5.4 6.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) DUF659 PF04937.15 KIK63358.1 - 0.0036 17.2 0.2 1.3 8.9 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) MFMR_assoc PF16596.5 KIK63362.1 - 0.076 13.5 3.1 0.15 12.5 3.1 1.5 1 1 0 1 1 1 0 Disordered region downstream of MFMR Cas_Csm6 PF09659.10 KIK63362.1 - 1.1 8.0 3.6 4.3 6.0 0.4 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csm6) ketoacyl-synt PF00109.26 KIK63364.1 - 9.2e-53 179.4 0.3 1.5e-52 178.7 0.3 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK63364.1 - 1.2e-41 143.3 0.1 1.9e-41 142.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KIK63364.1 - 2.2e-34 119.1 0.0 3.9e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KIK63364.1 - 2.4e-29 102.5 0.0 4.2e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KIK63364.1 - 5.4e-27 94.2 0.0 1.2e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIK63364.1 - 4.5e-15 56.1 0.0 9e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIK63364.1 - 1.8e-06 28.2 0.1 3.9e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 KIK63364.1 - 0.00057 19.7 0.2 0.0018 18.1 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KIK63364.1 - 0.0023 17.3 0.1 0.0046 16.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain YjeF_N PF03853.15 KIK63364.1 - 0.11 12.3 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus INPP5B_PH PF16776.5 KIK63365.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain zf-MYND PF01753.18 KIK63366.1 - 9.8e-10 38.4 13.4 2.9e-09 36.9 13.5 1.7 1 1 1 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIK63366.1 - 1.5 9.2 10.1 3.5 8.0 10.1 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Methyltransf_23 PF13489.6 KIK63369.1 - 6.6e-15 55.3 0.0 8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK63369.1 - 7.2e-12 45.4 0.0 8.1e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK63369.1 - 1.2e-11 45.1 0.0 2.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK63369.1 - 3.5e-11 43.7 0.0 1e-10 42.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63369.1 - 1.2e-08 35.6 0.0 4e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KIK63369.1 - 0.00044 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 KIK63369.1 - 0.00081 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KIK63369.1 - 0.0046 17.1 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIK63369.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KIK63369.1 - 0.084 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 KIK63369.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 KIK63369.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Metallothio_Pro PF02069.16 KIK63371.1 - 0.052 13.8 0.3 0.21 11.9 0.3 2.0 1 0 0 1 1 1 0 Prokaryotic metallothionein ketoacyl-synt PF00109.26 KIK63373.1 - 5.6e-54 183.4 0.3 1e-53 182.6 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK63373.1 - 1.2e-34 120.3 0.0 2.1e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KIK63373.1 - 2.8e-34 118.7 0.0 5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KIK63373.1 - 1.7e-30 106.3 0.0 3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KIK63373.1 - 3.9e-28 97.8 0.0 8.4e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIK63373.1 - 1.6e-14 54.3 0.0 3.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIK63373.1 - 3.7e-06 27.2 0.1 8.1e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 KIK63373.1 - 0.00072 19.4 0.3 0.0022 17.8 0.3 1.8 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KIK63373.1 - 0.0015 17.9 0.2 0.0029 17.0 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain YjeF_N PF03853.15 KIK63373.1 - 0.062 13.2 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus DEAD PF00270.29 KIK63377.1 - 1.2e-38 132.7 0.5 1.9e-38 132.0 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63377.1 - 5.2e-30 104.0 0.0 1.3e-28 99.5 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63377.1 - 0.00083 19.4 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIF_alpha PF05793.12 KIK63377.1 - 0.0084 14.8 25.7 0.016 13.8 25.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4604 PF15377.6 KIK63377.1 - 0.84 10.0 21.6 2 8.8 21.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) BUD22 PF09073.10 KIK63377.1 - 1 8.6 30.0 1.7 7.9 30.0 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 KIK63377.1 - 1.3 7.8 11.1 0.43 9.4 8.2 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 KIK63377.1 - 1.5 7.2 4.6 2 6.8 4.6 1.1 1 0 0 1 1 1 0 Macoilin family CDC27 PF09507.10 KIK63377.1 - 7 5.9 25.3 11 5.3 25.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 KIK63377.1 - 8.2 5.1 8.0 12 4.5 8.0 1.2 1 0 0 1 1 1 0 Presenilin zf-HIT PF04438.16 KIK63378.1 - 8.3e-09 35.2 10.3 1.2e-08 34.6 10.3 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 KIK63378.1 - 0.014 15.1 0.2 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain zf-ANAPC11 PF12861.7 KIK63378.1 - 0.045 13.8 2.0 0.071 13.2 2.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MYND PF01753.18 KIK63378.1 - 0.3 11.2 8.0 0.41 10.8 7.4 1.5 1 1 0 1 1 1 0 MYND finger Hexokinase_2 PF03727.16 KIK63379.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Hexokinase DUF4407 PF14362.6 KIK63379.1 - 0.5 9.7 2.8 11 5.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PT-HINT PF07591.11 KIK63381.1 - 0.07 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Pretoxin HINT domain Senescence PF06911.12 KIK63382.1 - 0.0032 17.8 6.7 0.087 13.1 0.8 2.0 1 1 1 2 2 2 2 Senescence-associated protein VPS13_C PF16909.5 KIK63382.1 - 0.034 13.9 6.8 0.38 10.5 1.1 2.1 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Collagen_mid PF15984.5 KIK63382.1 - 0.12 12.1 21.7 1.1 9.0 21.7 1.9 1 1 0 1 1 1 0 Bacterial collagen, middle region WES_acyltransf PF03007.16 KIK63382.1 - 0.21 11.3 2.8 0.32 10.7 0.5 1.9 1 1 1 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Synuclein PF01387.17 KIK63382.1 - 8.1 6.7 13.2 3 8.1 5.0 2.1 1 1 1 2 2 2 0 Synuclein DUF4618 PF15397.6 KIK63386.1 - 0.0084 15.6 4.0 0.0084 15.6 4.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Tropomyosin PF00261.20 KIK63386.1 - 0.017 14.5 4.9 0.028 13.8 4.9 1.2 1 0 0 1 1 1 0 Tropomyosin Wx5_PLAF3D7 PF09688.10 KIK63386.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) DUF745 PF05335.13 KIK63386.1 - 0.17 11.6 2.4 2.2 8.0 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK63386.1 - 0.86 9.5 4.9 5.4 7.0 0.3 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4503 PF14951.6 KIK63387.1 - 0.019 13.5 0.5 0.031 12.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Peptidase_S49_N PF08496.10 KIK63387.1 - 0.051 13.6 0.1 0.083 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK63387.1 - 0.17 10.7 5.7 0.25 10.2 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KIK63387.1 - 4.3 7.3 8.4 12 5.8 0.1 3.2 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ArabFuran-catal PF09206.11 KIK63388.1 - 3.7e-147 489.7 10.6 4.2e-147 489.5 10.6 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic DUF5500 PF17604.2 KIK63389.1 - 0.08 13.0 0.3 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5500) DUF3446 PF11928.8 KIK63389.1 - 0.45 10.8 23.3 1.4 9.3 3.6 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain F-box-like PF12937.7 KIK63390.1 - 2.2e-06 27.4 0.7 4.1e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like Neur_chan_memb PF02932.16 KIK63391.1 - 3.6 7.6 12.5 4.7 7.2 12.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DHR10 PF18595.1 KIK63395.1 - 0.031 14.3 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain IR1-M PF12185.8 KIK63395.1 - 0.045 13.7 0.0 0.68 9.9 0.0 2.1 1 1 1 2 2 2 0 Nup358/RanBP2 E3 ligase domain GPS2_interact PF15784.5 KIK63395.1 - 0.046 14.2 0.0 0.054 13.9 0.0 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain BLOC1_2 PF10046.9 KIK63395.1 - 0.082 13.2 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.13 KIK63395.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 DivIVA protein F-box-like PF12937.7 KIK63395.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 F-box-like Spc24 PF08286.11 KIK63395.1 - 0.16 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 LRR_9 PF14580.6 KIK63396.1 - 0.19 11.2 0.0 0.55 9.7 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat DUF4456 PF14644.6 KIK63397.1 - 0.0067 16.1 0.2 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) F-box-like_2 PF13013.6 KIK63397.1 - 0.095 12.7 0.2 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 F-box-like domain RPE65 PF03055.15 KIK63398.1 - 2.6e-110 369.8 0.0 2.9e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3455 PF11937.8 KIK63400.1 - 2.1e-23 83.4 0.0 2.9e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) RPE65 PF03055.15 KIK63401.1 - 9.5e-108 361.3 0.0 1.1e-107 361.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Thioesterase PF00975.20 KIK63402.1 - 5.1e-22 79.1 0.0 1.1e-21 78.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain KR PF08659.10 KIK63402.1 - 1.8e-15 57.3 0.0 3.6e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KIK63402.1 - 1.6e-11 44.4 0.1 3.4e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hydrolase_4 PF12146.8 KIK63402.1 - 0.066 12.5 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PutA_N PF18083.1 KIK63402.1 - 0.12 12.4 0.1 1.2 9.2 0.0 2.5 1 1 1 2 2 2 0 Proline utilization A N-terminal domain COG6 PF06419.11 KIK63403.1 - 8.7e-156 519.7 0.2 1.3e-155 519.2 0.2 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 TssC PF17541.2 KIK63403.1 - 0.051 12.4 0.1 0.11 11.3 0.1 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Sec34 PF04136.15 KIK63403.1 - 0.17 11.7 2.9 2.6 7.9 3.0 2.7 2 0 0 2 2 2 0 Sec34-like family SHOCT PF09851.9 KIK63403.1 - 1.2 8.9 8.6 5.4 6.9 0.0 3.4 3 0 0 3 3 3 0 Short C-terminal domain F-box-like PF12937.7 KIK63404.1 - 1.2e-09 37.9 0.7 2.9e-09 36.7 0.7 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK63404.1 - 0.048 13.5 0.6 0.45 10.4 0.6 2.3 1 1 0 1 1 1 0 F-box domain Sipho_Gp157 PF05565.11 KIK63404.1 - 0.19 11.7 0.1 0.26 11.3 0.1 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Helitron_like_N PF14214.6 KIK63406.1 - 2.4e-11 44.2 0.0 2.7e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK63407.1 - 0.002 17.4 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase YadA_anchor PF03895.15 KIK63407.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 YadA-like membrane anchor domain HSDR_N_2 PF13588.6 KIK63408.1 - 0.11 12.5 0.1 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) F-box-like PF12937.7 KIK63409.1 - 2.5e-10 40.1 1.0 4.2e-10 39.4 1.0 1.4 1 0 0 1 1 1 1 F-box-like Phage_term_smal PF05944.12 KIK63409.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Phage small terminase subunit Cupin_4 PF08007.12 KIK63410.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein RE_AlwI PF09491.10 KIK63411.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF2380 PF09533.10 KIK63411.1 - 0.15 11.7 0.6 0.39 10.3 0.6 1.6 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) OTT_1508_deam PF14441.6 KIK63412.1 - 3e-06 27.2 0.1 6.6e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase BppU_N PF10651.9 KIK63412.1 - 0.15 11.7 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 BppU N-terminal domain P53_TAD PF08563.11 KIK63412.1 - 0.93 9.1 3.4 3 7.5 0.2 3.1 3 0 0 3 3 3 0 P53 transactivation motif F-box PF00646.33 KIK63413.1 - 0.00047 19.9 0.3 0.0078 16.1 0.1 2.6 2 0 0 2 2 2 1 F-box domain zinc_ribbon_6 PF14599.6 KIK63415.1 - 0.17 11.9 1.4 0.47 10.5 1.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon Skp1_POZ PF03931.15 KIK63416.1 - 1.8e-20 72.9 0.0 4.8e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KIK63416.1 - 1.6e-17 63.4 0.0 3.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Ribonuc_red_sm PF00268.21 KIK63420.1 - 5.2e-114 380.4 0.6 6.3e-114 380.1 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain AMP-binding PF00501.28 KIK63424.1 - 3.6e-34 118.1 0.0 5.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK63424.1 - 7.8e-29 100.6 0.0 1.3e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KIK63424.1 - 4.4e-11 43.0 0.4 1.2e-10 41.6 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIK63424.1 - 4.9e-05 22.9 0.0 0.00084 18.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK63424.1 - 0.0079 15.2 0.0 0.045 12.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KIK63424.1 - 0.066 13.1 0.5 0.63 9.9 0.0 2.6 3 0 0 3 3 3 0 KR domain F-box-like PF12937.7 KIK63425.1 - 1.6e-09 37.5 0.3 1.6e-09 37.5 0.3 2.7 3 0 0 3 3 3 1 F-box-like Fungal_trans PF04082.18 KIK63427.1 - 8e-23 80.8 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK63427.1 - 5.2e-10 39.3 10.8 1e-09 38.3 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoLip_ATPase_C PF16212.5 KIK63428.1 - 9.7e-73 245.0 31.0 9.7e-73 245.0 31.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK63428.1 - 2.5e-23 81.5 0.3 6e-23 80.3 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KIK63428.1 - 2.6e-13 49.8 0.0 5.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK63428.1 - 3.8e-12 46.9 0.1 1.1e-06 29.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIK63428.1 - 7.1e-05 22.4 1.7 7.1e-05 22.4 1.7 3.9 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIK63428.1 - 0.004 16.9 0.1 0.047 13.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK63428.1 - 0.059 13.8 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK63428.1 - 0.19 11.8 0.4 0.81 9.7 0.0 2.2 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KIK63429.1 - 9.7e-10 38.2 5.5 1.4e-09 37.7 2.7 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK63429.1 - 1.1 9.2 10.7 0.15 12.0 3.8 3.1 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK63430.1 - 5.5e-08 32.6 3.4 2.2e-07 30.6 3.4 2.1 1 1 0 1 1 1 1 F-box-like zf-dskA_traR PF01258.17 KIK63430.1 - 0.0094 15.9 0.2 0.02 14.8 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger APG17 PF04108.12 KIK63430.1 - 0.042 13.0 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 F-box-like_2 PF13013.6 KIK63430.1 - 0.062 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain Adeno_E3B PF03376.14 KIK63431.1 - 0.44 10.8 1.6 3.1 8.1 0.0 2.8 4 0 0 4 4 4 0 Adenovirus E3B protein F-box-like PF12937.7 KIK63432.1 - 8.5e-06 25.6 1.2 3.2e-05 23.7 1.2 2.1 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK63432.1 - 0.042 13.8 0.1 0.084 12.9 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KIK63433.1 - 5.4e-06 26.2 2.6 1.4e-05 24.9 1.1 2.6 2 1 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KIK63433.1 - 0.026 14.5 0.1 0.068 13.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KIK63434.1 - 5.6e-08 32.6 0.1 5.6e-08 32.6 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.6 KIK63434.1 - 0.027 14.4 0.1 0.094 12.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like domain MBD_C PF14048.6 KIK63435.1 - 1.1 10.1 3.5 0.8 10.5 0.6 2.1 1 1 2 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 zf-HIT PF04438.16 KIK63436.1 - 3.6e-08 33.1 11.1 5.5e-08 32.5 11.1 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KIK63436.1 - 4.1 7.6 14.7 0.14 12.3 8.8 1.5 2 0 0 2 2 2 0 MYND finger TRAM_LAG1_CLN8 PF03798.16 KIK63437.1 - 0.00011 22.0 13.2 0.00021 21.1 13.2 1.4 1 1 0 1 1 1 1 TLC domain OAD_gamma PF04277.13 KIK63438.1 - 0.062 13.9 0.0 0.42 11.2 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TPR_10 PF13374.6 KIK63439.1 - 3.1e-71 233.5 0.1 5.7e-11 41.9 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63439.1 - 5e-50 167.7 10.7 4.3e-11 42.9 0.1 6.9 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK63439.1 - 2.6e-11 43.5 3.0 4.9e-06 26.1 0.2 3.1 1 1 3 4 4 4 3 MalT-like TPR region TPR_8 PF13181.6 KIK63439.1 - 9.7e-11 41.0 7.7 0.14 12.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK63439.1 - 4.8e-09 35.6 5.4 3.7 7.8 0.1 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK63439.1 - 3.8e-08 33.2 9.3 0.053 13.9 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK63439.1 - 4.1e-07 30.4 1.8 0.58 10.7 0.1 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK63439.1 - 2.3e-05 24.0 7.4 12 5.9 0.2 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63439.1 - 0.00037 20.4 4.2 56 4.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KIK63439.1 - 0.038 14.2 1.4 58 4.3 0.0 5.0 5 0 0 5 5 5 0 PPR repeat Erythrovirus_X PF06795.11 KIK63439.1 - 0.083 13.2 0.5 36 4.8 0.0 4.2 5 0 0 5 5 5 0 Erythrovirus X protein DUF3972 PF13118.6 KIK63439.1 - 0.14 12.6 6.4 8 6.9 0.1 4.6 2 1 2 5 5 5 0 Protein of unknown function (DUF3972) ANAPC3 PF12895.7 KIK63439.1 - 0.23 11.7 5.6 3.6 7.9 0.2 4.1 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2552 PF10827.8 KIK63439.1 - 0.25 11.6 0.8 9.4 6.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2552) SERTA PF06031.13 KIK63439.1 - 6.7 6.5 6.8 75 3.1 0.1 4.4 4 0 0 4 4 4 0 SERTA motif FAD_binding_3 PF01494.19 KIK63442.1 - 7.5e-08 32.0 2.6 0.00092 18.6 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KIK63442.1 - 1.2e-05 24.4 0.4 0.093 11.6 0.2 3.1 2 1 1 3 3 3 3 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK63442.1 - 0.00037 19.8 0.1 0.00066 19.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK63442.1 - 0.00039 20.1 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK63442.1 - 0.007 16.6 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIK63442.1 - 0.0075 15.7 0.5 0.014 14.8 0.5 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK63442.1 - 0.0077 15.3 0.6 0.015 14.4 0.6 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KIK63442.1 - 0.01 15.0 0.5 0.014 14.5 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK63442.1 - 0.021 13.9 0.5 0.048 12.7 0.4 1.6 1 1 1 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KIK63442.1 - 0.032 12.9 0.5 0.049 12.3 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK63442.1 - 0.034 14.1 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK63442.1 - 0.055 12.7 0.5 0.1 11.8 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK63442.1 - 0.21 10.8 0.1 0.89 8.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Ferritin-like PF12902.7 KIK63443.1 - 4e-43 147.9 0.0 6.2e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like LodA_N PF17990.1 KIK63444.1 - 3.1e-53 180.9 0.0 5.3e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 L-Lysine epsilon oxidase N-terminal LodA_C PF18417.1 KIK63444.1 - 1.5e-27 96.2 0.2 6.1e-27 94.2 0.2 1.9 1 1 0 1 1 1 1 L-lysine epsilon oxidase C-terminal domain Trp_halogenase PF04820.14 KIK63445.1 - 3e-09 36.3 0.4 0.00057 18.9 0.0 3.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK63445.1 - 3e-08 33.3 0.5 0.019 14.2 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK63445.1 - 0.00024 20.4 0.1 0.00051 19.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK63445.1 - 0.00026 20.7 0.2 0.0005 19.7 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK63445.1 - 0.00031 20.0 0.3 0.00047 19.4 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK63445.1 - 0.00034 20.1 1.1 0.0012 18.3 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK63445.1 - 0.001 18.2 1.5 0.0015 17.7 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK63445.1 - 0.0033 17.6 0.1 0.019 15.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK63445.1 - 0.0041 16.4 0.1 0.016 14.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KIK63445.1 - 0.0045 15.8 0.1 0.0071 15.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KIK63445.1 - 0.0047 16.0 0.2 0.009 15.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK63445.1 - 0.0086 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK63445.1 - 0.019 14.2 0.2 0.031 13.5 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK63445.1 - 0.069 12.3 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Ferritin-like PF12902.7 KIK63446.1 - 1.1e-44 152.9 0.0 1.6e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like LodA_N PF17990.1 KIK63447.1 - 1.9e-47 162.0 0.0 5.5e-47 160.5 0.0 1.7 2 0 0 2 2 2 1 L-Lysine epsilon oxidase N-terminal LodA_C PF18417.1 KIK63447.1 - 1e-27 96.7 0.1 4e-27 94.8 0.1 1.8 1 1 0 1 1 1 1 L-lysine epsilon oxidase C-terminal domain LRR_6 PF13516.6 KIK63448.1 - 3.6e-10 39.1 25.2 0.0059 16.6 0.3 8.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 KIK63448.1 - 5.9e-07 29.2 1.3 24 6.0 0.1 6.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 KIK63448.1 - 0.00011 22.5 9.1 0.55 10.7 2.5 5.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK63448.1 - 0.0002 21.0 11.4 2.2 8.1 2.5 6.3 5 2 1 6 6 6 3 Leucine rich repeat Piwi PF02171.17 KIK63449.1 - 7.7e-75 251.9 0.0 1.1e-74 251.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK63449.1 - 2e-21 77.1 0.1 3.6e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIK63449.1 - 2.1e-16 59.3 0.1 5.1e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIK63449.1 - 3.5e-09 36.9 0.0 7.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK63449.1 - 5.4e-08 33.0 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute TSGA13 PF14994.6 KIK63449.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Testis-specific gene 13 protein DraK_HK_N PF18092.1 KIK63449.1 - 0.24 11.9 1.0 57 4.2 0.0 3.3 3 0 0 3 3 3 0 DraK Histidine Kinase N-terminal domain ketoacyl-synt PF00109.26 KIK63451.1 - 3.5e-52 177.5 1.7 2.3e-51 174.8 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK63451.1 - 6.2e-37 127.8 0.0 1.2e-36 126.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIK63451.1 - 1.1e-32 113.4 0.1 2.4e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KIK63451.1 - 1.5e-29 102.4 0.3 3.3e-29 101.3 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KIK63451.1 - 4.9e-21 75.9 1.6 2.7e-20 73.5 0.1 2.8 3 0 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 KIK63451.1 - 6.1e-21 74.9 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KIK63451.1 - 1.5e-09 38.0 0.2 4.1e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KIK63451.1 - 5.8e-08 32.4 0.1 5.1e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KIK63451.1 - 4e-06 26.8 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KIK63451.1 - 1.2e-05 24.9 1.1 0.00022 20.7 0.1 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 KIK63451.1 - 4.9e-05 23.3 0.0 0.0013 18.7 0.0 3.3 4 0 0 4 4 3 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KIK63451.1 - 6e-05 22.7 0.1 0.0007 19.2 0.0 2.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 KIK63451.1 - 0.0011 18.8 2.7 0.016 15.0 2.7 2.7 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_12 PF08242.12 KIK63451.1 - 0.0014 19.3 0.0 0.0045 17.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KIK63451.1 - 0.002 18.5 0.0 0.046 14.2 0.0 2.9 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KIK63451.1 - 0.028 15.5 0.1 0.54 11.3 0.0 3.4 3 1 1 4 4 1 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KIK63451.1 - 0.064 13.1 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 KIK63451.1 - 0.067 13.1 0.2 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) 3Beta_HSD PF01073.19 KIK63451.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family rve_3 PF13683.6 KIK63455.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 KIK63455.1 - 0.0028 17.9 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KIK63456.1 - 2.2e-05 24.9 0.0 3.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK63456.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease FlaC_arch PF05377.11 KIK63461.1 - 0.024 15.0 0.4 0.024 15.0 0.4 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4939 PF16297.5 KIK63462.1 - 0.022 14.6 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) ChuX_HutX PF06228.13 KIK63467.1 - 0.069 12.9 0.1 0.3 10.9 0.0 2.0 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX Pil1 PF13805.6 KIK63468.1 - 1.5e-11 44.3 7.7 2.4e-11 43.7 7.7 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FUSC PF04632.12 KIK63468.1 - 0.0079 14.8 2.7 0.0095 14.5 2.7 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF3958 PF13125.6 KIK63468.1 - 0.014 15.5 10.9 0.031 14.5 10.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) PHM7_cyt PF14703.6 KIK63468.1 - 0.037 14.3 10.6 0.03 14.5 8.6 1.8 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Bacillus_HBL PF05791.11 KIK63468.1 - 0.09 12.6 5.8 0.15 11.9 1.7 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Rb_C PF08934.10 KIK63468.1 - 0.096 12.5 1.3 0.15 11.9 1.3 1.3 1 0 0 1 1 1 0 Rb C-terminal domain DUF3510 PF12022.8 KIK63468.1 - 0.17 12.3 9.6 0.1 13.0 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) FapA PF03961.13 KIK63468.1 - 0.2 10.2 3.8 0.24 10.0 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Synaptobrevin PF00957.21 KIK63468.1 - 1.4 8.8 4.9 1.3 8.9 1.5 2.5 1 1 0 2 2 2 0 Synaptobrevin UPF0242 PF06785.11 KIK63468.1 - 1.7 8.7 11.0 3 7.9 11.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 KIK63468.1 - 2.5 8.5 8.9 3.5 8.1 8.9 1.2 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 KIK63468.1 - 3.6 7.9 13.3 1.9 8.8 10.4 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1772 PF08592.11 KIK63469.1 - 4.2e-21 75.7 3.9 5.6e-21 75.3 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1852 PF08908.11 KIK63470.1 - 0.00013 21.1 0.0 0.00015 20.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1852) SH3_15 PF18346.1 KIK63470.1 - 0.15 12.4 0.3 6.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain PGAP1 PF07819.13 KIK63472.1 - 2.5e-06 27.4 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIK63472.1 - 6.2e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KIK63472.1 - 9.1e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KIK63472.1 - 0.00086 20.0 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KIK63472.1 - 0.0017 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 KIK63472.1 - 0.008 16.2 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 KIK63472.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 KIK63472.1 - 0.034 13.7 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LCAT PF02450.15 KIK63472.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1772 PF08592.11 KIK63473.1 - 3.9e-21 75.8 2.5 5.3e-21 75.4 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KIK63474.1 - 2.5e-43 148.4 21.8 2.5e-43 148.4 21.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK63474.1 - 2.3e-18 66.3 0.5 2.3e-18 66.3 0.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Cytochrom_B561 PF03188.16 KIK63474.1 - 0.79 9.9 5.8 0.28 11.3 1.1 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Dyp_perox PF04261.12 KIK63475.1 - 1.5e-10 40.6 0.0 4.3e-09 35.8 0.0 2.7 1 1 0 1 1 1 1 Dyp-type peroxidase family Mito_carr PF00153.27 KIK63477.1 - 4.9e-54 180.2 0.3 5.9e-17 61.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 KIK63479.1 - 4.1e-14 52.8 0.0 5.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK63479.1 - 1.4e-09 38.9 0.0 1.9e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK63479.1 - 7.3e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIK63479.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK63479.1 - 0.0034 16.7 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIK63479.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 KIK63479.1 - 0.23 10.1 0.0 0.65 8.7 0.0 1.8 1 1 0 1 1 1 0 Ndr family DTHCT PF08070.11 KIK63480.1 - 0.3 11.9 12.1 0.38 11.5 12.1 1.1 1 0 0 1 1 1 0 DTHCT (NUC029) region Ig_5 PF16681.5 KIK63481.1 - 0.0099 16.3 0.2 0.01 16.2 0.2 1.2 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain F-box-like PF12937.7 KIK63481.1 - 0.027 14.4 0.4 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KIK63481.1 - 0.04 13.8 1.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 F-box domain GatD_N PF18195.1 KIK63481.1 - 0.043 13.1 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 GatD N-terminal domain Ig_4 PF16680.5 KIK63481.1 - 0.064 13.5 3.2 0.15 12.4 3.1 1.7 1 1 1 2 2 2 0 T-cell surface glycoprotein CD3 delta chain PMI_typeI PF01238.21 KIK63482.1 - 2.7e-66 224.3 0.0 3.8e-64 217.2 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KIK63482.1 - 2.7e-05 23.8 0.1 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KIK63482.1 - 0.00027 20.8 0.0 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK63482.1 - 0.021 14.5 0.1 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) MFS_1 PF07690.16 KIK63483.1 - 6.7e-31 107.5 31.3 1e-30 106.9 31.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIK63483.1 - 6.8e-06 25.2 9.1 2.3e-05 23.4 9.1 1.7 1 1 0 1 1 1 1 MFS_1 like family Solute_trans_a PF03619.16 KIK63485.1 - 1.6e-94 316.3 13.5 2e-94 316.1 13.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Fungus-induced PF10917.8 KIK63485.1 - 0.18 12.1 2.6 1.2 9.5 2.6 2.5 1 0 0 1 1 1 0 Fungus-induced protein GATA PF00320.27 KIK63486.1 - 5.8e-30 102.6 19.2 2.8e-15 55.6 4.8 2.3 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIK63486.1 - 3.2e-05 23.3 5.6 0.0063 16.0 0.6 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 KIK63486.1 - 5.2e-05 23.3 7.1 0.0076 16.4 0.5 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3268 PF11672.8 KIK63486.1 - 0.00056 20.2 1.0 0.14 12.5 0.1 2.2 1 1 1 2 2 2 1 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KIK63486.1 - 0.0037 17.4 6.2 0.77 9.9 1.0 2.7 2 1 1 3 3 3 2 Zinc ribbon domain DZR PF12773.7 KIK63486.1 - 0.0054 16.7 8.7 0.58 10.2 9.7 2.9 1 1 1 2 2 2 2 Double zinc ribbon FAM163 PF15069.6 KIK63486.1 - 0.039 14.4 0.9 0.046 14.2 0.9 1.3 1 0 0 1 1 1 0 FAM163 family Cytochrom_c3_2 PF14537.6 KIK63486.1 - 0.053 14.0 6.9 0.081 13.4 6.6 1.5 1 1 0 1 1 1 0 Cytochrome c3 Elf1 PF05129.13 KIK63486.1 - 0.057 13.5 5.7 0.1 12.6 1.2 2.3 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 KIK63486.1 - 0.057 13.5 6.5 1.5 9.0 1.7 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger eIF-5_eIF-2B PF01873.17 KIK63486.1 - 0.061 13.2 8.4 1.3 8.9 1.3 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-CHY PF05495.12 KIK63486.1 - 0.14 12.6 5.7 8.5 6.9 5.7 2.3 1 1 0 1 1 1 0 CHY zinc finger OTT_1508_deam PF14441.6 KIK63486.1 - 0.16 12.0 8.2 1.5 8.8 1.5 2.5 2 1 1 3 3 2 0 OTT_1508-like deaminase zf-RRN7 PF11781.8 KIK63486.1 - 0.2 11.4 8.7 0.53 10.0 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HIPIP PF01355.17 KIK63486.1 - 0.2 12.0 9.5 4.4 7.7 1.3 3.4 1 1 2 3 3 3 0 High potential iron-sulfur protein zinc_ribbon_15 PF17032.5 KIK63486.1 - 0.27 12.0 8.1 6.6 7.6 8.8 2.6 1 1 1 2 2 2 0 zinc-ribbon family FYVE PF01363.21 KIK63486.1 - 0.42 10.8 6.2 11 6.2 5.9 2.4 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.22 KIK63486.1 - 0.75 9.7 6.2 1.9 8.4 1.1 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 KIK63486.1 - 1.1 9.5 11.7 0.93 9.7 1.4 3.4 3 1 0 3 3 3 0 B-box zinc finger C1_2 PF03107.16 KIK63486.1 - 2.4 8.5 11.0 8.8 6.7 0.1 3.5 2 2 1 3 3 3 0 C1 domain Prim_Zn_Ribbon PF08273.12 KIK63486.1 - 2.9 8.2 6.5 4.4 7.7 0.6 2.6 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase ZF-HD_dimer PF04770.12 KIK63486.1 - 3 8.3 9.0 10 6.5 2.2 2.8 2 1 0 2 2 2 0 ZF-HD protein dimerisation region Nudix_N_2 PF14803.6 KIK63486.1 - 4.1 7.4 8.9 4.6 7.3 0.5 3.5 2 2 0 2 2 2 0 Nudix N-terminal Tnp_zf-ribbon_2 PF13842.6 KIK63486.1 - 4.4 8.2 11.2 5.1 8.0 1.9 2.8 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Cytochrome_C7 PF14522.6 KIK63486.1 - 6.1 6.9 10.6 2.5e+02 1.7 10.6 2.3 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Rubredoxin_2 PF18073.1 KIK63486.1 - 8.3 6.2 11.9 33 4.3 0.3 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain Ras_bdg_2 PF14847.6 KIK63488.1 - 3.3e-05 24.1 0.0 4.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Prot_ATP_ID_OB PF16450.5 KIK63488.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Redoxin PF08534.10 KIK63489.1 - 4.6e-36 123.7 0.0 5.2e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIK63489.1 - 8.2e-11 41.9 0.0 9.2e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Dyp_perox PF04261.12 KIK63490.1 - 1.6e-10 40.5 0.0 6.9e-05 22.0 0.0 2.5 2 1 0 2 2 2 2 Dyp-type peroxidase family Dyp_perox PF04261.12 KIK63491.1 - 9.9e-10 37.9 0.0 2.8e-08 33.1 0.0 2.8 2 1 0 2 2 2 1 Dyp-type peroxidase family Dyp_perox PF04261.12 KIK63492.1 - 9.5e-08 31.4 0.0 1.8e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 Dyp-type peroxidase family Acid_PPase PF12689.7 KIK63493.1 - 1.2e-60 204.2 0.0 1.4e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 KIK63493.1 - 0.075 13.3 0.0 1 9.6 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK63493.1 - 0.2 11.7 0.4 1.2 9.2 0.3 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 KIK63494.1 - 7.5e-76 248.1 30.5 1.1e-11 45.0 0.4 10.1 9 1 1 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK63494.1 - 4.3e-29 100.7 3.9 0.00014 22.0 0.1 8.0 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK63494.1 - 2.4e-16 59.9 0.0 0.082 12.2 0.0 6.4 6 1 1 7 7 7 4 WD40-like domain Nup160 PF11715.8 KIK63494.1 - 1.5e-14 53.5 5.6 0.08 11.6 0.1 6.7 4 1 3 7 7 7 5 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK63494.1 - 6.3e-14 52.3 0.4 0.00029 20.8 0.0 4.2 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK63494.1 - 8e-13 48.0 0.8 0.00066 18.7 0.2 5.2 4 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK63494.1 - 1.7e-11 43.8 1.0 2 8.5 0.1 8.0 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK63494.1 - 8.2e-07 27.9 4.9 0.0046 15.5 0.0 4.1 2 1 3 5 5 5 2 Cytochrome D1 heme domain nos_propeller PF18764.1 KIK63494.1 - 1.1e-06 28.4 2.4 2.6 8.0 0.0 6.5 7 1 1 8 8 7 1 Nitrous oxide reductase propeller repeat DUF5570 PF17731.1 KIK63494.1 - 0.00017 21.6 8.8 1.7 8.7 0.1 5.3 3 1 3 6 6 6 2 Family of unknown function (DUF5570) SdiA-regulated PF06977.11 KIK63494.1 - 0.0028 16.9 0.0 12 5.1 0.0 4.7 4 1 1 5 5 5 0 SdiA-regulated Nucleoporin_N PF08801.11 KIK63494.1 - 0.01 14.6 8.0 1.9 7.1 1.0 3.8 1 1 2 3 3 3 0 Nup133 N terminal like MAM PF00629.23 KIK63494.1 - 0.028 14.3 4.5 0.86 9.5 1.4 3.1 2 1 1 3 3 3 0 MAM domain, meprin/A5/mu Tae4 PF14113.6 KIK63494.1 - 0.084 13.1 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 Gryzun-like PF12742.7 KIK63494.1 - 0.14 12.2 0.0 22 5.1 0.0 3.5 4 0 0 4 4 4 0 Gryzun, putative Golgi trafficking NHL PF01436.21 KIK63494.1 - 0.25 11.4 4.6 89 3.4 0.0 5.2 7 0 0 7 7 7 0 NHL repeat Proteasome_A_N PF10584.9 KIK63494.1 - 0.28 10.9 4.8 1.5e+02 2.2 0.1 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PALB2_WD40 PF16756.5 KIK63494.1 - 0.53 9.1 5.3 10 5.0 0.2 4.2 3 2 3 6 6 6 0 Partner and localizer of BRCA2 WD40 domain DUF5122 PF17164.4 KIK63494.1 - 2.1 8.7 7.4 50 4.3 0.0 5.1 8 0 0 8 8 7 0 Domain of unknown function (DUF5122) beta-propeller Glyco_hydro_16 PF00722.21 KIK63495.1 - 1.8e-10 40.5 0.9 2.5e-10 40.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM-like PF14683.6 KIK63496.1 - 7.6e-28 97.5 1.9 1.5e-27 96.5 0.6 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KIK63496.1 - 4.1e-22 77.7 0.1 9e-22 76.6 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Phytase-like PF13449.6 KIK63497.1 - 1.5e-36 126.8 0.3 2.2e-36 126.3 0.3 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Astro_capsid_p2 PF16580.5 KIK63497.1 - 0.054 12.9 0.2 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 C-terminal tail of astrovirus capsid projection or spike SdiA-regulated PF06977.11 KIK63497.1 - 0.074 12.3 0.0 0.35 10.0 0.0 2.0 1 1 0 1 1 1 0 SdiA-regulated Phytase-like PF13449.6 KIK63498.1 - 3.1e-37 129.1 0.3 4e-37 128.7 0.3 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 KIK63498.1 - 0.16 11.2 0.0 0.87 8.8 0.0 2.1 1 1 0 1 1 1 0 SdiA-regulated adh_short PF00106.25 KIK63499.1 - 4.1e-33 114.5 0.2 2.7e-32 111.8 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK63499.1 - 1.3e-18 67.4 0.0 5.7e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK63499.1 - 2.8e-05 24.1 0.1 7.3e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK63499.1 - 0.00073 19.1 0.0 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Adeno_PIX PF03955.14 KIK63499.1 - 0.016 15.4 0.2 0.029 14.5 0.2 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Abhydrolase_4 PF08386.10 KIK63500.1 - 4.7e-10 39.5 0.0 4.5e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein NmrA PF05368.13 KIK63503.1 - 5.8e-38 130.8 0.0 6.9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK63503.1 - 1.4e-10 41.4 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK63503.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK63504.1 - 3e-25 89.2 0.0 5.1e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK63504.1 - 2.4e-05 24.3 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding PIG-P PF08510.12 KIK63505.1 - 0.027 14.4 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 PIG-P Ribonuclease_T2 PF00445.18 KIK63506.1 - 3.1e-37 128.6 0.2 4.6e-37 128.0 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4131 PF13567.6 KIK63509.1 - 5 6.8 5.6 10 5.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1461 PF07314.11 KIK63509.1 - 7.9 6.3 11.3 0.98 9.3 3.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) FHA PF00498.26 KIK63510.1 - 6.1e-11 42.5 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KIK63510.1 - 1.5e-09 37.4 9.4 2.5e-09 36.7 9.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KIK63510.1 - 4.6e-09 36.5 9.9 6.8e-09 35.9 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK63510.1 - 4.8e-05 23.1 9.3 7.5e-05 22.5 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK63510.1 - 0.00011 22.4 6.5 0.00023 21.4 6.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK63510.1 - 0.00023 21.1 1.7 0.00037 20.5 1.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KIK63510.1 - 0.00029 20.6 9.9 0.00045 20.0 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK63510.1 - 0.011 15.6 7.5 0.018 15.0 7.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KIK63510.1 - 0.046 13.6 4.1 0.073 13.0 4.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KIK63510.1 - 0.051 13.6 10.1 0.092 12.8 10.1 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK63510.1 - 0.17 11.8 5.0 0.26 11.2 5.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.12 KIK63510.1 - 0.62 9.8 4.6 0.92 9.2 4.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_4 PF15227.6 KIK63510.1 - 1.5 9.1 7.5 2.9 8.1 7.5 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1688 PF07958.11 KIK63511.1 - 0.025 13.3 0.1 0.057 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Retrotran_gag_2 PF14223.6 KIK63512.1 - 1.7e-14 53.7 0.0 2.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KIK63512.1 - 0.015 15.4 1.1 0.028 14.5 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KIK63512.1 - 0.057 13.1 0.7 0.12 12.2 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Auts2 PF15336.6 KIK63514.1 - 0.071 13.2 8.7 0.068 13.3 8.7 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein CPT PF07931.12 KIK63514.1 - 0.078 12.8 1.7 0.077 12.8 1.7 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Kin17_mid PF10357.9 KIK63514.1 - 0.12 12.3 2.9 0.13 12.2 2.9 1.1 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Atrophin-1 PF03154.15 KIK63514.1 - 1.8 6.7 15.8 2.4 6.4 15.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family EF-hand_6 PF13405.6 KIK63515.1 - 0.031 14.2 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KIK63515.1 - 0.066 12.8 0.1 0.22 11.2 0.1 2.0 1 0 0 1 1 1 0 EF hand DUF948 PF06103.11 KIK63515.1 - 0.084 13.1 2.2 1 9.6 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) EF-hand_5 PF13202.6 KIK63515.1 - 0.089 12.3 0.2 0.25 10.9 0.2 1.8 1 0 0 1 1 1 0 EF hand HIP1_clath_bdg PF16515.5 KIK63515.1 - 0.099 13.3 1.3 0.38 11.4 1.3 2.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ApoLp-III PF07464.11 KIK63515.1 - 0.11 12.5 6.2 2.8 8.0 1.0 3.7 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Syntaxin_2 PF14523.6 KIK63515.1 - 0.14 12.5 8.5 2.7 8.4 3.3 4.0 3 1 0 3 3 3 0 Syntaxin-like protein BLOC1S3 PF15753.5 KIK63515.1 - 0.14 12.2 1.1 0.5 10.5 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 TFIIE_alpha PF02002.17 KIK63515.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.4 2 1 0 2 2 2 0 TFIIE alpha subunit DUF16 PF01519.16 KIK63515.1 - 0.31 11.5 7.5 16 6.0 3.5 4.4 4 2 0 4 4 4 0 Protein of unknown function DUF16 MFS_1 PF07690.16 KIK63516.1 - 1.5e-17 63.6 43.8 1.8e-17 63.3 40.6 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily NACHT PF05729.12 KIK63517.1 - 0.0015 18.5 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK63517.1 - 0.0049 16.1 0.0 0.0062 15.8 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KIK63517.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 KIK63517.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK63517.1 - 0.031 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KIK63517.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 KIK63517.1 - 0.19 11.1 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 KIK63518.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK63518.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 KIK63519.1 - 0.61 10.3 4.0 0.2 11.8 0.9 1.9 2 0 0 2 2 2 0 Zinc knuckle ResIII PF04851.15 KIK63521.1 - 0.0018 18.3 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK63521.1 - 0.01 15.6 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Lipase_3 PF01764.25 KIK63522.1 - 2.3e-22 79.4 0.0 4.1e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK63522.1 - 0.00052 20.7 2.0 0.0023 18.6 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK63522.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KIK63522.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 KIK63522.1 - 0.099 12.1 0.2 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Cullin_binding PF03556.15 KIK63523.1 - 1.8e-26 92.9 0.2 2.6e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Cullin binding zf-C3HC4_2 PF13923.6 KIK63525.1 - 4.1e-09 36.1 15.1 4.3e-09 36.1 11.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK63525.1 - 3e-07 30.3 10.7 3e-07 30.3 10.7 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK63525.1 - 4.9e-07 29.5 14.7 9.8e-07 28.5 10.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK63525.1 - 7e-07 29.0 15.6 8.9e-07 28.7 12.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK63525.1 - 1.1e-06 28.8 12.2 1.1e-06 28.8 12.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIK63525.1 - 2.4e-06 27.6 12.3 2.4e-06 27.6 12.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIK63525.1 - 4.7e-06 26.5 11.8 4.7e-06 26.5 11.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.27 KIK63525.1 - 7.7e-05 22.3 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain Prok-RING_4 PF14447.6 KIK63525.1 - 0.00018 21.3 13.7 0.068 13.0 10.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KIK63525.1 - 0.00034 20.7 5.3 0.00086 19.4 5.3 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KIK63525.1 - 0.00099 18.9 7.8 0.00099 18.9 7.8 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein TRAF6_Z2 PF18048.1 KIK63525.1 - 0.014 15.4 3.2 0.019 15.0 0.2 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-rbx1 PF12678.7 KIK63525.1 - 0.018 15.3 8.8 0.018 15.3 8.8 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain U-box PF04564.15 KIK63525.1 - 0.056 13.6 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 U-box domain YABBY PF04690.13 KIK63525.1 - 3.8 8.1 10.3 0.28 11.7 0.3 3.0 3 0 0 3 3 3 0 YABBY protein zf-RING_4 PF14570.6 KIK63525.1 - 3.9 7.4 13.9 1.7 8.5 9.9 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_28 PF00295.17 KIK63527.1 - 3e-48 164.5 11.4 3.7e-48 164.3 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 KIK63528.1 - 6.2e-41 140.0 2.9 4e-40 137.4 2.9 1.8 1 1 0 1 1 1 1 Pectinesterase FeS_assembly_P PF01883.19 KIK63529.1 - 8.2e-14 51.5 0.0 2.5e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein PsaN PF05479.11 KIK63529.1 - 0.076 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) FAD-oxidase_C PF02913.19 KIK63530.1 - 2.6e-56 191.0 0.0 3.7e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK63530.1 - 2.9e-28 98.4 0.0 4.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PsbM PF05151.12 KIK63531.1 - 0.19 11.6 5.3 0.29 10.9 5.3 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) GREB1 PF15782.5 KIK63532.1 - 4.6 4.2 13.5 5.4 4.0 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-RING_4 PF14570.6 KIK63533.1 - 4.2e-21 74.5 11.6 6.8e-21 73.8 11.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KIK63533.1 - 2.8e-05 23.9 9.4 5.3e-05 23.0 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIK63533.1 - 0.00095 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 KIK63533.1 - 0.017 15.0 9.7 1 9.2 10.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK63533.1 - 0.03 14.7 12.1 0.062 13.6 12.1 1.6 1 0 0 1 1 1 0 Ring finger domain Baculo_IE-1 PF05290.11 KIK63533.1 - 0.081 12.9 4.1 0.15 12.0 4.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 KIK63533.1 - 0.64 10.1 7.1 4.8 7.3 7.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 KIK63533.1 - 4.5 7.5 10.8 0.091 12.9 3.1 2.2 3 0 0 3 3 3 0 Zinc-binding RING-finger UDG PF03167.19 KIK63534.1 - 4.2e-17 62.6 0.0 6.5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF3788 PF12663.7 KIK63534.1 - 0.094 12.7 0.1 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) Rep_fac-A_3 PF08661.11 KIK63535.1 - 2.7e-18 66.2 0.1 3.1e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Myosin_N PF02736.19 KIK63535.1 - 0.022 14.6 0.7 0.022 14.6 0.7 1.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Rad51 PF08423.11 KIK63536.1 - 1.4e-14 54.0 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KIK63536.1 - 3.6e-08 33.2 0.0 5.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KIK63536.1 - 5.4e-08 32.5 0.4 1.8e-07 30.8 0.4 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KIK63536.1 - 2.1e-06 27.4 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 KIK63536.1 - 0.0012 19.1 0.1 0.0091 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK63536.1 - 0.0013 18.5 0.1 0.0025 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK63536.1 - 0.0022 18.4 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KIK63536.1 - 0.0032 16.6 2.4 0.48 9.4 0.3 2.2 1 1 1 2 2 2 2 Type II/IV secretion system protein PRK PF00485.18 KIK63536.1 - 0.018 14.8 0.1 0.039 13.7 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DnaB_C PF03796.15 KIK63536.1 - 0.026 13.8 0.2 0.23 10.8 0.2 2.0 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain PSY3 PF16836.5 KIK63536.1 - 0.033 13.7 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description ATPase_2 PF01637.18 KIK63536.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KIK63536.1 - 0.078 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KIK63536.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NUDIX PF00293.28 KIK63537.1 - 5.3e-20 71.8 2.9 1.6e-19 70.2 2.9 1.7 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIK63537.1 - 0.014 15.4 0.3 0.027 14.5 0.3 1.5 1 1 0 1 1 1 0 NUDIX domain Cupredoxin_1 PF13473.6 KIK63538.1 - 2.6e-05 24.3 1.5 0.033 14.3 0.2 3.5 2 2 2 4 4 4 2 Cupredoxin-like domain Cu_bind_like PF02298.17 KIK63538.1 - 0.00067 19.6 4.3 0.79 9.8 0.2 3.6 2 2 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 KIK63538.1 - 0.007 16.8 3.0 1.3 9.5 0.1 3.4 3 1 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family CzcE PF16986.5 KIK63538.1 - 0.031 14.6 0.7 5.2 7.5 0.0 3.6 3 0 0 3 3 3 0 Heavy-metal resistance protein CzcE CusF_Ec PF11604.8 KIK63538.1 - 0.054 13.5 0.8 9.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF dsDNA_bind PF01984.20 KIK63539.1 - 6.4e-25 87.6 8.3 7.1e-25 87.4 8.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain YjbH PF06082.11 KIK63539.1 - 0.048 12.5 0.6 0.049 12.5 0.6 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Ca_bind_SSO6904 PF18249.1 KIK63539.1 - 0.057 13.8 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 Calcium binding protein SSO6904 ERCC4 PF02732.15 KIK63540.1 - 6.2e-26 91.5 0.3 1.2e-25 90.5 0.3 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KIK63540.1 - 0.014 15.7 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain FA_desaturase PF00487.24 KIK63541.1 - 4.1 7.2 9.3 9.3 6.0 9.0 1.9 1 1 0 1 1 1 0 Fatty acid desaturase TcpE PF12648.7 KIK63541.1 - 9.9 6.8 6.6 5.9 7.5 4.5 1.7 1 1 1 2 2 2 0 TcpE family F-box_4 PF15966.5 KIK63542.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box UCH_1 PF13423.6 KIK63543.1 - 7.2e-84 282.1 0.0 9.5e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KIK63543.1 - 1.2e-20 74.8 0.0 2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 KIK63543.1 - 3.1e-06 27.8 0.3 0.034 15.0 0.1 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK63543.1 - 0.00065 19.9 0.0 19 5.6 0.0 4.6 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KIK63543.1 - 0.022 14.6 0.2 0.97 9.5 0.1 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Acetyltransf_10 PF13673.7 KIK63544.1 - 1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK63544.1 - 1.3e-05 25.6 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK63544.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KIK63544.1 - 0.012 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KIK63544.1 - 0.043 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIK63544.1 - 0.051 13.7 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MerC PF03203.14 KIK63545.1 - 9.4 6.7 9.7 0.88 10.0 1.0 2.9 1 1 1 3 3 3 0 MerC mercury resistance protein Choline_transpo PF04515.12 KIK63546.1 - 3.1e-38 131.8 5.5 5.1e-38 131.1 1.8 2.6 2 1 0 2 2 2 1 Plasma-membrane choline transporter Glyco_hydro_10 PF00331.20 KIK63548.1 - 1.4e-98 330.0 0.0 1.6e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KIK63548.1 - 2.3e-13 49.9 4.6 2.3e-13 49.9 4.6 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain MPP6 PF10175.9 KIK63549.1 - 1.6e-06 28.6 0.5 8.2e-06 26.4 0.0 2.1 2 1 0 2 2 2 1 M-phase phosphoprotein 6 SOG2 PF10428.9 KIK63550.1 - 1.6e-93 314.7 14.3 1.6e-93 314.7 14.3 3.2 2 1 1 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 KIK63550.1 - 1.4e-12 47.1 1.4 4.5e-09 35.9 0.2 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIK63550.1 - 3e-10 40.2 8.1 2.3e-05 24.7 0.2 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIK63550.1 - 0.0012 18.4 1.0 0.002 17.6 1.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KIK63550.1 - 0.085 13.5 3.2 37 5.4 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 KIK63550.1 - 0.35 11.0 1.0 36 4.8 0.2 2.8 2 0 0 2 2 2 0 Leucine Rich repeat MFS_1 PF07690.16 KIK63552.1 - 2.8e-15 56.1 42.3 2.8e-15 56.1 42.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK63552.1 - 0.00021 20.7 20.5 0.00087 18.7 20.5 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Glyco_hydro_127 PF07944.12 KIK63553.1 - 5.8e-21 74.6 0.0 4.1e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 DUF2781 PF10914.8 KIK63554.1 - 1.2e-43 149.0 8.2 1.4e-43 148.8 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) YwiC PF14256.6 KIK63554.1 - 0.84 10.0 5.0 0.2 12.0 1.6 1.7 2 1 0 2 2 2 0 YwiC-like protein Cofilin_ADF PF00241.20 KIK63555.1 - 8.9e-36 122.4 0.0 5.7e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein 4HBT PF03061.22 KIK63556.1 - 3.1e-06 27.5 0.1 4.5e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DIOX_N PF14226.6 KIK63557.1 - 2.1e-15 57.5 0.0 4.4e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK63557.1 - 6.3e-13 49.1 0.0 1.8e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK63558.1 - 2.2e-16 60.7 0.1 9.5e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK63558.1 - 1.8e-11 44.4 0.0 3.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ubiquitin PF00240.23 KIK63559.1 - 8.3e-26 89.5 0.1 9.1e-26 89.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK63559.1 - 9.4e-14 51.0 0.1 1e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIK63559.1 - 1.1e-05 25.3 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KIK63559.1 - 0.00057 20.3 0.0 0.00066 20.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK63559.1 - 0.016 15.3 0.1 0.061 13.4 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 KIK63559.1 - 0.019 15.5 0.0 0.028 14.9 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 SAP18 PF06487.12 KIK63560.1 - 1.8e-34 118.9 0.0 2.5e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_transf_52 PF07922.11 KIK63560.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 52 MIS13 PF08202.11 KIK63561.1 - 3.6e-16 59.3 12.4 2.5e-15 56.6 12.3 2.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family FtsK_gamma PF09397.10 KIK63561.1 - 0.042 13.7 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Ftsk gamma domain PIF1 PF05970.14 KIK63562.1 - 0.00036 19.8 0.0 0.0026 17.0 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase Ribosomal_60s PF00428.19 KIK63562.1 - 0.4 11.3 5.3 16 6.2 4.2 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein SAYSvFN PF10260.9 KIK63563.1 - 8.4 6.4 0.0 8.4 6.4 0.0 4.3 4 1 1 5 5 5 0 Uncharacterized conserved domain (SAYSvFN) DUF3535 PF12054.8 KIK63564.1 - 3.8e-99 332.9 0.0 1.6e-97 327.5 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KIK63564.1 - 1.8e-67 227.5 0.1 3.4e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK63564.1 - 1.5e-16 60.7 0.0 6.4e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 KIK63564.1 - 4.5e-10 38.9 21.9 0.096 13.0 0.3 9.4 10 0 0 10 10 9 4 HEAT repeat ResIII PF04851.15 KIK63564.1 - 6.4e-05 23.0 0.2 0.00034 20.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CLASP_N PF12348.8 KIK63564.1 - 0.00091 18.9 0.5 0.0099 15.5 0.0 3.0 3 1 1 4 4 4 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 KIK63564.1 - 0.0011 19.5 0.0 0.86 10.2 0.0 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KIK63564.1 - 0.0082 16.6 17.1 4.7 7.8 0.1 8.5 9 1 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.7 KIK63564.1 - 0.076 13.1 0.1 53 3.8 0.0 3.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.14 KIK63564.1 - 0.079 12.1 0.1 0.18 10.9 0.1 1.6 1 0 0 1 1 1 0 Dopey, N-terminal ERCC3_RAD25_C PF16203.5 KIK63564.1 - 0.16 11.1 0.2 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase TAF6_C PF07571.13 KIK63564.1 - 0.49 10.7 4.0 3.8 7.9 0.0 3.8 5 0 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain Cupin_8 PF13621.6 KIK63565.1 - 1.7e-33 116.4 0.2 2.3e-33 116.0 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KIK63565.1 - 1.9e-07 30.9 0.1 1.1e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KIK63565.1 - 5.1e-07 30.1 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIK63565.1 - 0.0036 17.0 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KIK63565.1 - 0.081 12.8 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK63565.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) FYVE PF01363.21 KIK63566.1 - 1.1e-17 63.9 2.8 2.1e-17 63.0 2.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KIK63566.1 - 1.4e-15 56.7 0.6 3.1e-15 55.6 0.6 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 KIK63566.1 - 0.005 16.8 4.8 0.015 15.3 4.8 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.16 KIK63566.1 - 0.062 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_28 PF00295.17 KIK63568.1 - 2.2e-58 197.8 18.6 2.8e-58 197.5 18.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1565 PF07602.11 KIK63568.1 - 0.0045 16.3 9.6 0.014 14.8 8.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1565) Fungus-induced PF10917.8 KIK63568.1 - 0.34 11.2 2.1 0.78 10.1 0.0 2.7 3 0 0 3 3 3 0 Fungus-induced protein Arylsulfotran_2 PF14269.6 KIK63569.1 - 1.3e-60 205.3 0.4 1.7e-60 204.9 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK63569.1 - 5.9e-15 55.1 0.1 4.6e-13 48.8 0.1 2.7 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) zf-MYND PF01753.18 KIK63570.1 - 2e-07 31.0 13.5 4.2e-07 30.0 13.5 1.5 1 0 0 1 1 1 1 MYND finger T2SSM PF04612.12 KIK63570.1 - 7.6 6.6 11.3 1.2 9.2 6.9 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M CoA_trans PF01144.23 KIK63571.1 - 5.4e-101 336.5 4.0 3.5e-61 206.4 0.3 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KIK63571.1 - 2.6e-05 24.2 0.1 4.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK63571.1 - 0.037 14.0 0.3 0.32 10.9 0.0 2.6 4 0 0 4 4 4 0 Acetyl-CoA hydrolase/transferase N-terminal domain FmdA_AmdA PF03069.15 KIK63572.1 - 1.2e-160 534.4 0.0 1.4e-160 534.2 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pectate_lyase_3 PF12708.7 KIK63573.1 - 2.2e-93 312.1 13.5 4.7e-79 265.2 5.3 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIK63573.1 - 1.5e-08 34.2 0.6 0.00038 20.1 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase SMI1_KNR4 PF09346.10 KIK63574.1 - 9.5e-23 81.1 0.0 2.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) P16-Arc PF04699.14 KIK63575.1 - 1.3e-52 178.2 0.1 1.5e-52 178.1 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KIK63575.1 - 0.00025 21.3 0.1 0.00047 20.4 0.0 1.4 2 0 0 2 2 2 1 Dip2/Utp12 Family Aldedh PF00171.22 KIK63576.1 - 3.8e-118 394.9 0.0 4.7e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HMG_box PF00505.19 KIK63578.1 - 1.2e-15 57.7 0.2 1.5e-15 57.3 0.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK63578.1 - 0.00068 20.2 0.0 0.001 19.6 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KIK63578.1 - 0.019 14.3 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Mitoc_mL59 PF18126.1 KIK63578.1 - 0.12 12.7 1.0 0.15 12.4 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Esterase_phd PF10503.9 KIK63579.1 - 7.6e-24 84.4 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIK63579.1 - 2.1e-09 37.2 1.4 3.3e-09 36.5 1.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIK63579.1 - 0.0061 16.2 0.4 0.0084 15.8 0.3 1.4 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 KIK63579.1 - 0.014 14.3 0.2 0.021 13.7 0.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family Esterase_phd PF10503.9 KIK63580.1 - 2.1e-23 83.0 0.0 3.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KIK63580.1 - 5.5e-11 42.2 1.3 5.5e-11 42.2 1.3 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KIK63580.1 - 5.7e-10 39.0 0.2 8.4e-10 38.5 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KIK63580.1 - 0.00056 18.9 0.3 0.00083 18.3 0.3 1.2 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KIK63580.1 - 0.012 15.3 0.4 0.021 14.5 0.4 1.5 1 1 0 1 1 1 0 Putative esterase HSA PF07529.13 KIK63582.1 - 6.9e-13 48.7 0.1 6.9e-13 48.7 0.1 2.7 2 0 0 2 2 2 1 HSA Myb_DNA-binding PF00249.31 KIK63582.1 - 2.8e-08 33.8 1.0 7.1e-08 32.5 1.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK63582.1 - 5e-08 33.1 2.4 1.6e-07 31.5 2.4 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain BCIP PF13862.6 KIK63582.1 - 0.019 14.7 1.4 0.054 13.3 0.0 2.4 2 0 0 2 2 2 0 p21-C-terminal region-binding protein NAD_binding_6 PF08030.12 KIK63583.1 - 5.2e-36 124.1 0.0 1.2e-35 122.9 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK63583.1 - 8e-25 87.1 0.0 1.7e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIK63583.1 - 2.5e-17 63.2 9.3 2.5e-17 63.2 9.3 2.6 2 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KIK63583.1 - 0.066 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Cellulase PF00150.18 KIK63584.1 - 4.9e-08 32.8 0.0 4.9e-08 32.8 0.0 2.0 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) AF-4 PF05110.13 KIK63584.1 - 0.98 7.4 5.5 1.6 6.8 5.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IATP PF04568.12 KIK63585.1 - 0.017 15.5 3.1 0.018 15.4 2.5 1.4 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ECM11 PF15463.6 KIK63587.1 - 0.0031 18.1 0.1 0.007 16.9 0.1 1.6 1 0 0 1 1 1 1 Extracellular mutant protein 11 CEND1 PF15677.5 KIK63587.1 - 0.87 10.1 7.8 6.7 7.3 0.2 2.6 1 1 1 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 FA_desaturase PF00487.24 KIK63589.1 - 5.6e-14 52.6 21.3 5.6e-14 52.6 21.3 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK63589.1 - 0.00048 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GST_N_3 PF13417.6 KIK63590.1 - 6.9e-06 26.4 0.4 1.9e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK63590.1 - 3.5e-05 24.0 0.2 0.0001 22.5 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK63590.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK63591.1 - 1.5e-07 31.7 0.1 3.1e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK63591.1 - 6.2e-07 29.6 0.1 1.2e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK63591.1 - 0.0041 17.1 0.7 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK63591.1 - 0.0058 16.8 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ubiquitin PF00240.23 KIK63592.1 - 8.2e-27 92.8 0.1 9.3e-27 92.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK63592.1 - 1.3e-11 44.2 0.2 1.4e-11 44.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIK63592.1 - 0.00085 19.2 0.0 0.00097 19.0 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIK63592.1 - 0.021 15.2 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK63592.1 - 0.053 13.6 0.0 0.071 13.2 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pectate_lyase_3 PF12708.7 KIK63593.1 - 9.4e-92 306.7 12.2 1.6e-76 256.9 3.2 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIK63593.1 - 3.1e-09 36.4 1.4 0.002 17.8 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RsdA_SigD_bd PF16751.5 KIK63594.1 - 0.084 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region DUF3040 PF11239.8 KIK63594.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Acetyltransf_13 PF13880.6 KIK63595.1 - 4.6e-18 65.0 0.0 9.6e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KIK63595.1 - 4.5e-08 32.8 2.7 7.3e-08 32.1 2.7 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KIK63595.1 - 1.1e-05 25.7 0.0 0.0013 19.1 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK63595.1 - 0.00087 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK63595.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK63595.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-C2H2_4 PF13894.6 KIK63596.1 - 4.3e-06 27.1 7.8 0.013 16.2 0.4 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK63596.1 - 6.8e-06 26.3 5.7 0.00044 20.5 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK63596.1 - 3.5e-05 24.0 6.1 0.0099 16.3 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type HypA PF01155.19 KIK63596.1 - 0.059 13.4 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 KIK63596.1 - 0.085 13.2 1.8 2.6 8.4 0.2 2.3 1 1 1 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.10 KIK63596.1 - 0.087 13.0 2.5 2.6 8.2 2.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain CpXC PF14353.6 KIK63596.1 - 0.09 12.8 0.8 0.56 10.3 0.0 2.1 1 1 1 2 2 2 0 CpXC protein Elf1 PF05129.13 KIK63596.1 - 0.095 12.8 0.5 0.18 11.9 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 KIK63596.1 - 0.1 12.5 0.6 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-met PF12874.7 KIK63596.1 - 0.11 12.9 8.3 2.3 8.7 0.7 3.1 3 1 1 4 4 3 0 Zinc-finger of C2H2 type DZR PF12773.7 KIK63596.1 - 0.12 12.4 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 KIK63596.1 - 0.14 12.5 2.6 13 6.2 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-dskA_traR PF01258.17 KIK63596.1 - 0.17 11.9 1.1 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2H2_11 PF16622.5 KIK63596.1 - 0.2 11.4 0.7 22 4.9 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type GATA PF00320.27 KIK63596.1 - 0.41 10.3 2.2 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-AN1 PF01428.16 KIK63596.1 - 1.5 9.0 4.6 4.1 7.6 0.4 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger GATase_2 PF00310.21 KIK63597.1 - 8.8e-177 588.0 0.0 1.3e-176 587.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KIK63597.1 - 2.1e-154 514.1 0.0 3.2e-154 513.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KIK63597.1 - 8.5e-112 373.2 0.0 2.6e-110 368.3 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KIK63597.1 - 8.5e-87 289.7 4.4 1.4e-86 288.9 4.4 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KIK63597.1 - 2e-24 86.3 0.0 1.2e-23 83.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KIK63597.1 - 4.5e-22 78.0 0.1 9e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KIK63597.1 - 8.6e-08 32.3 0.0 3e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK63597.1 - 1.6e-07 30.9 0.0 0.017 14.4 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK63597.1 - 1.6e-07 31.8 0.1 0.00027 21.4 0.0 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK63597.1 - 2.9e-07 30.4 0.1 0.0022 17.6 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK63597.1 - 2.8e-05 23.0 1.6 3.1e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FMN_dh PF01070.18 KIK63597.1 - 0.00053 19.1 0.4 0.0072 15.4 0.8 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Amino_oxidase PF01593.24 KIK63597.1 - 0.00058 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KIK63597.1 - 0.0042 16.2 0.0 0.0042 16.2 0.0 2.8 3 0 0 3 3 2 1 FAD binding domain FAD_binding_3 PF01494.19 KIK63597.1 - 0.0087 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KIK63597.1 - 0.011 16.1 0.4 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 KIK63597.1 - 0.016 15.3 0.1 12 5.9 0.0 3.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK63597.1 - 0.017 14.4 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GATase_6 PF13522.6 KIK63597.1 - 0.019 15.2 0.2 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase domain FAD_oxidored PF12831.7 KIK63597.1 - 0.021 14.2 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK63597.1 - 0.041 13.1 1.1 0.085 12.1 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KIK63597.1 - 0.12 11.4 0.1 1 8.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIK63597.1 - 0.18 11.1 0.4 0.55 9.6 0.0 2.0 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 KIK63597.1 - 0.18 10.1 0.1 4.1 5.7 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KIK63597.1 - 0.31 10.1 1.1 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.32 KIK63598.1 - 2.6e-40 135.6 19.7 9.5e-13 48.4 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK63598.1 - 5.8e-15 55.4 1.7 0.00018 21.7 0.0 5.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK63598.1 - 1.3e-07 30.9 1.9 0.057 12.4 0.0 4.1 1 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK63598.1 - 1.9e-05 23.5 0.5 0.35 9.5 0.1 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.11 KIK63598.1 - 0.00032 20.5 0.3 0.17 11.5 0.1 2.6 1 1 1 3 3 3 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KIK63598.1 - 0.00065 18.6 1.0 0.079 11.7 0.1 3.8 1 1 3 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 KIK63598.1 - 0.0037 16.2 2.0 0.024 13.6 0.1 2.6 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain HPS3_N PF14761.6 KIK63598.1 - 0.016 14.7 0.0 0.13 11.7 0.0 2.4 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 PAN_3 PF08277.12 KIK63598.1 - 0.029 14.2 0.2 0.51 10.2 0.0 2.7 3 0 0 3 3 3 0 PAN-like domain Frtz PF11768.8 KIK63598.1 - 0.066 11.5 0.0 0.12 10.7 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz FLgD_tudor PF13861.6 KIK63599.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 FlgD Tudor-like domain 2OG-FeII_Oxy_2 PF13532.6 KIK63600.1 - 2.3e-10 41.0 0.0 2.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 KIK63601.1 - 8.5e-08 32.0 0.0 0.0034 17.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein CHORD PF04968.12 KIK63602.1 - 4.5e-47 158.6 12.9 1.2e-23 83.5 1.2 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KIK63602.1 - 2.2e-16 60.6 0.1 4.8e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.19 KIK63602.1 - 0.004 16.9 6.4 0.81 9.6 0.3 3.5 4 0 0 4 4 4 2 BTK motif RhoGAP-FF1 PF16512.5 KIK63602.1 - 0.16 12.7 0.1 13 6.5 0.0 2.5 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain GTP_EFTU PF00009.27 KIK63603.1 - 1.2e-32 113.1 3.0 5.7e-31 107.6 3.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIK63603.1 - 1.3e-29 102.4 0.8 1.3e-29 102.4 0.8 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KIK63603.1 - 4.5e-08 33.2 1.2 1.1e-07 31.9 0.3 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.15 KIK63603.1 - 8.8e-06 25.5 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 KIK63603.1 - 0.00017 21.1 0.0 0.00041 19.8 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK63603.1 - 0.00079 19.6 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK63603.1 - 0.0034 16.9 1.8 0.0059 16.1 0.2 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KIK63603.1 - 0.0042 17.0 1.2 0.99 9.3 0.1 3.0 1 1 1 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KIK63603.1 - 0.005 16.6 2.1 1.3 8.8 0.4 2.8 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF1805 PF08827.11 KIK63603.1 - 0.09 13.1 0.0 0.64 10.4 0.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Scramblase PF03803.15 KIK63604.1 - 2.7e-54 183.8 0.0 3.6e-53 180.1 0.0 2.0 1 1 0 1 1 1 1 Scramblase CDC45 PF02724.14 KIK63605.1 - 5.2e-217 722.1 0.0 6.2e-217 721.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 KIK63605.1 - 0.0073 16.5 2.5 0.011 15.8 2.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Stn1 PF10451.9 KIK63606.1 - 1.3e-05 24.3 0.6 0.00073 18.6 0.7 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KIK63606.1 - 0.0068 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-Mss51 PF13824.6 KIK63607.1 - 4.6e-23 81.1 11.9 8.1e-23 80.3 11.9 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF3530 PF12048.8 KIK63607.1 - 0.059 12.8 1.2 0.092 12.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) His_Phos_1 PF00300.22 KIK63609.1 - 8.6e-16 58.2 0.1 1.7e-15 57.2 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IGPD PF00475.18 KIK63610.1 - 1.2e-60 204.0 0.1 1.5e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Peptidase_M13_N PF05649.13 KIK63611.1 - 1e-108 364.4 0.0 1.4e-108 364.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KIK63611.1 - 3.9e-57 193.2 0.0 7.7e-57 192.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 MFS_1 PF07690.16 KIK63612.1 - 2.1e-27 96.0 25.3 2.1e-27 96.0 25.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK63612.1 - 9.9e-10 37.9 7.3 9.9e-10 37.9 7.3 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter 2OG-FeII_Oxy_2 PF13532.6 KIK63613.1 - 6.1e-25 88.6 0.0 8.7e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M24 PF00557.24 KIK63614.1 - 2.1e-38 132.1 0.0 2.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KIK63614.1 - 1e-09 39.2 0.0 1.1e-08 35.8 0.0 2.5 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain HopA1 PF17914.1 KIK63614.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 HopA1 effector protein family MFS_1 PF07690.16 KIK63616.1 - 1.4e-27 96.6 26.0 1.4e-27 96.6 26.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK63616.1 - 0.00072 18.1 0.6 0.0014 17.1 0.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_Mycoplasma PF07672.13 KIK63616.1 - 0.039 13.3 0.4 0.09 12.1 0.4 1.6 1 0 0 1 1 1 0 Mycoplasma MFS transporter FAD_binding_4 PF01565.23 KIK63617.1 - 6.5e-19 68.0 0.1 1.6e-18 66.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK63617.1 - 2.9e-08 33.7 0.1 6.6e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like AMP-binding PF00501.28 KIK63618.1 - 2.3e-84 283.5 0.0 3e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK63618.1 - 0.00043 21.2 0.0 0.00095 20.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zinc_ribbon_15 PF17032.5 KIK63619.1 - 8.3e-06 26.5 0.0 1.3e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 zinc-ribbon family FYVE_2 PF02318.16 KIK63619.1 - 0.033 14.4 0.2 1.5 9.1 0.0 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger EF-hand_1 PF00036.32 KIK63620.1 - 1.3e-22 77.6 0.0 3.4e-06 26.2 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KIK63620.1 - 2.4e-20 70.6 0.3 7.1e-06 25.5 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KIK63620.1 - 2.9e-16 59.7 0.0 1.4e-07 31.8 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KIK63620.1 - 2.1e-12 46.7 1.2 2.1e-07 30.7 0.0 4.4 3 3 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KIK63620.1 - 2.2e-12 45.8 0.0 0.0041 16.6 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KIK63620.1 - 0.037 14.0 0.3 0.074 13.0 0.3 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SKG6 PF08693.10 KIK63621.1 - 5.8e-06 25.6 1.0 1.6e-05 24.2 1.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SCF PF02404.15 KIK63621.1 - 0.007 15.7 0.1 0.0081 15.5 0.1 1.1 1 0 0 1 1 1 1 Stem cell factor Nitrate_red_gam PF02665.14 KIK63621.1 - 0.038 13.5 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Sporozoite_P67 PF05642.11 KIK63621.1 - 0.042 11.9 8.9 0.055 11.5 8.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4448 PF14610.6 KIK63621.1 - 0.066 13.0 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Apt1 PF10351.9 KIK63621.1 - 0.16 10.8 1.8 0.16 10.8 1.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM154 PF15102.6 KIK63621.1 - 0.19 11.7 0.3 0.3 11.0 0.3 1.3 1 1 0 1 1 1 0 TMEM154 protein family HAD_2 PF13419.6 KIK63622.1 - 7.4e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK63622.1 - 0.0026 18.1 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK63622.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Acid_PPase PF12689.7 KIK63622.1 - 0.02 14.8 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Hydrolase_6 PF13344.6 KIK63622.1 - 0.2 11.8 0.0 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase QCR10 PF09796.9 KIK63623.1 - 3.4e-20 71.9 0.1 4.1e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 KIK63623.1 - 0.0027 17.6 0.1 0.0097 15.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Nop16 PF09420.10 KIK63624.1 - 4.1e-41 141.3 0.0 5.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zn_clus PF00172.18 KIK63625.1 - 6.2e-07 29.4 5.3 1.4e-06 28.3 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UL42 PF17638.2 KIK63625.1 - 0.07 13.1 3.8 0.22 11.5 0.3 2.7 2 0 0 2 2 2 0 HCMV UL42 Pro-kuma_activ PF09286.11 KIK63626.1 - 3.8e-36 124.5 0.9 3.5e-35 121.4 0.2 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK63626.1 - 1.7e-05 24.2 0.2 2.9e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Subtilase family IML1 PF12257.8 KIK63627.1 - 1.4e-108 362.4 0.0 2.2e-108 361.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KIK63627.1 - 1.4e-15 57.1 0.1 3.2e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Asp PF00026.23 KIK63628.1 - 9.3e-42 143.5 0.4 2.8e-41 142.0 0.4 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK63628.1 - 2.4e-05 24.6 2.0 0.0013 19.0 2.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Ras PF00071.22 KIK63629.1 - 5.2e-65 218.0 1.0 6.2e-65 217.7 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK63629.1 - 1.3e-36 125.5 0.1 2.2e-36 124.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK63629.1 - 2.8e-17 62.7 0.2 3.6e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK63629.1 - 2.4e-07 30.8 1.0 0.0028 17.6 0.3 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIK63629.1 - 3.2e-06 26.8 0.4 9.2e-06 25.3 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KIK63629.1 - 2.1e-05 24.0 0.1 2.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK63629.1 - 2.2e-05 23.9 0.1 2.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK63629.1 - 4.6e-05 23.5 1.4 5.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KIK63629.1 - 0.0013 18.3 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KIK63629.1 - 0.0031 17.9 0.1 0.01 16.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK63629.1 - 0.0031 17.9 0.4 0.61 10.5 0.0 2.6 1 1 2 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIK63629.1 - 0.0063 16.2 0.3 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK63629.1 - 0.013 15.8 0.7 0.088 13.1 0.0 2.4 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK63629.1 - 0.019 15.5 0.1 0.15 12.6 0.0 2.1 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 KIK63629.1 - 0.019 14.5 0.1 0.094 12.2 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.14 KIK63629.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KIK63629.1 - 0.073 12.3 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin TniB PF05621.11 KIK63629.1 - 0.089 12.2 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KIK63629.1 - 0.14 11.7 1.0 2.2 7.8 0.0 2.5 2 2 0 2 2 2 0 AAA domain Cyclin_N PF00134.23 KIK63630.1 - 3.4e-10 39.7 0.0 9.9e-10 38.2 0.0 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIK63630.1 - 0.029 14.7 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain Img2 PF05046.14 KIK63633.1 - 2.5e-20 72.5 0.0 2.9e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SOR_SNZ PF01680.17 KIK63634.1 - 6.5e-113 375.6 4.9 9.3e-113 375.1 4.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KIK63634.1 - 8.7e-10 38.3 3.1 9e-07 28.4 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KIK63634.1 - 3e-05 23.3 0.2 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KIK63634.1 - 0.0002 20.6 0.8 0.046 12.9 0.0 2.9 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 KIK63634.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 KIK63634.1 - 0.0017 17.8 3.3 0.057 12.8 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KIK63634.1 - 0.0031 17.0 0.2 0.14 11.6 0.0 2.8 2 1 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 KIK63634.1 - 0.0086 15.1 0.6 0.039 13.0 0.0 2.2 2 1 0 3 3 3 1 FMN-dependent dehydrogenase IGPS PF00218.21 KIK63634.1 - 0.011 14.9 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase zf-MYND PF01753.18 KIK63636.1 - 1e-11 44.7 13.4 2.7e-11 43.3 13.4 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK63636.1 - 0.14 12.5 9.5 0.36 11.2 9.5 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SKIP_SNW PF02731.15 KIK63637.1 - 1.7e-71 239.1 1.0 1.7e-71 239.1 1.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain SRP-alpha_N PF04086.13 KIK63638.1 - 7.2e-48 164.0 12.9 8.6e-47 160.5 12.9 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KIK63638.1 - 8.3e-46 156.1 0.1 8.9e-45 152.7 0.1 2.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KIK63638.1 - 1.8e-08 34.5 0.5 6.5e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KIK63638.1 - 1.8e-05 23.9 0.1 4.4e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KIK63638.1 - 0.0037 17.0 0.1 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KIK63638.1 - 0.0076 16.3 0.0 0.024 14.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KIK63638.1 - 0.022 14.5 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK63638.1 - 0.027 14.4 0.1 0.099 12.6 0.1 1.9 1 1 0 1 1 1 0 NTPase Fer4_NifH PF00142.18 KIK63638.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KIK63638.1 - 0.095 11.9 0.5 3.8 6.6 0.1 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_31 PF13614.6 KIK63638.1 - 0.14 12.1 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 KIK63639.1 - 4.4e-09 36.6 0.2 5.1e-09 36.4 0.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK63639.1 - 0.00097 19.7 0.0 0.001 19.6 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain PTP_tm PF18861.1 KIK63641.1 - 0.01 15.8 1.6 0.011 15.8 0.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J BatA PF07584.11 KIK63641.1 - 0.017 15.5 0.1 0.031 14.6 0.1 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal EphA2_TM PF14575.6 KIK63641.1 - 0.037 14.9 0.0 0.11 13.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GT87 PF09594.10 KIK63641.1 - 0.086 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 Stevor PF17410.2 KIK63641.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.5 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame Adeno_E3_CR2 PF02439.15 KIK63641.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KIK63641.1 - 0.23 10.9 0.2 0.56 9.7 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KIK63641.1 - 0.4 10.7 2.2 1.1 9.3 2.2 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TrbL PF04610.14 KIK63641.1 - 4.3 7.0 5.6 3.1 7.5 3.1 2.1 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein CytochromB561_N PF09786.9 KIK63641.1 - 5.9 5.8 21.0 6.7 5.6 21.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal HAGH_C PF16123.5 KIK63642.1 - 1.2e-20 73.8 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KIK63642.1 - 0.0026 17.8 8.0 0.19 11.7 8.0 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily FTO_NTD PF12933.7 KIK63642.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 FTO catalytic domain Got1 PF04178.12 KIK63643.1 - 2.5e-28 98.7 20.0 3.3e-28 98.4 20.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3566 PF12089.8 KIK63643.1 - 0.61 10.5 12.0 0.93 9.9 11.6 1.5 1 1 1 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Amidohydro_1 PF01979.20 KIK63645.1 - 7.1e-16 58.5 0.0 6.5e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK63645.1 - 1.1e-14 54.9 0.1 2.1e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Pectinesterase PF01095.19 KIK63645.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Pectinesterase bZIP_2 PF07716.15 KIK63646.1 - 6.3e-11 42.2 11.4 6.3e-11 42.2 11.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK63646.1 - 3.3e-06 27.1 8.4 3.3e-06 27.1 8.4 1.9 2 0 0 2 2 2 1 bZIP transcription factor DUF2205 PF10224.9 KIK63646.1 - 0.033 14.2 1.4 0.082 12.9 1.4 1.7 1 0 0 1 1 1 0 Short coiled-coil protein Prefoldin_2 PF01920.20 KIK63646.1 - 0.05 13.6 1.1 0.05 13.6 1.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit TSC22 PF01166.18 KIK63646.1 - 0.17 12.2 0.2 0.17 12.2 0.2 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family ECM11 PF15463.6 KIK63646.1 - 0.17 12.4 3.7 0.24 12.0 0.0 2.5 2 1 0 2 2 2 0 Extracellular mutant protein 11 SR-25 PF10500.9 KIK63646.1 - 0.22 11.1 15.0 0.017 14.8 10.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Seryl_tRNA_N PF02403.22 KIK63646.1 - 0.48 10.7 5.2 0.19 12.0 1.6 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TFIIA PF03153.13 KIK63646.1 - 0.57 10.1 12.2 0.74 9.7 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 KIK63646.1 - 2.6 6.1 6.4 3.8 5.5 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PGI PF00342.19 KIK63647.1 - 1.8e-234 778.8 1.0 2.1e-234 778.6 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase TFIID_30kDa PF03540.13 KIK63648.1 - 3.9e-26 90.7 0.1 8.1e-26 89.7 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KIK63648.1 - 0.012 15.6 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated EF-hand_14 PF17959.1 KIK63648.1 - 0.047 14.0 0.0 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain TAF4 PF05236.14 KIK63648.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RHH_7 PF16777.5 KIK63649.1 - 0.13 12.6 2.0 0.32 11.4 2.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG MFS_1 PF07690.16 KIK63650.1 - 2.4e-36 125.4 21.1 2.4e-36 125.4 21.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK63650.1 - 1.4e-15 57.2 3.9 1.4e-15 57.2 3.9 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIK63650.1 - 3.6e-07 29.0 1.0 6.3e-07 28.2 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3040 PF11239.8 KIK63650.1 - 0.23 11.7 3.9 0.69 10.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) FAD_binding_3 PF01494.19 KIK63651.1 - 4.5e-21 75.5 0.0 3.7e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK63651.1 - 3e-11 43.5 0.8 0.00018 21.2 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK63651.1 - 1.5e-08 33.9 0.1 0.00013 20.9 0.2 2.3 1 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KIK63651.1 - 3.8e-08 32.8 0.2 5.6e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK63651.1 - 5.9e-08 32.3 0.0 1.6e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK63651.1 - 3.6e-07 30.3 0.1 1.1e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK63651.1 - 2.2e-06 27.0 0.1 1.1e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KIK63651.1 - 5.3e-06 26.9 0.0 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK63651.1 - 8e-06 24.8 0.2 2.5e-05 23.2 0.5 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KIK63651.1 - 5e-05 22.5 0.1 7.6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK63651.1 - 0.00052 19.5 0.2 0.00075 19.0 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK63651.1 - 0.0056 16.0 0.5 0.0082 15.4 0.5 1.2 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KIK63651.1 - 0.012 14.7 0.0 0.049 12.7 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 KIK63651.1 - 0.013 14.8 0.5 0.04 13.2 0.1 2.0 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIK63651.1 - 0.021 14.1 0.0 0.069 12.4 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIK63651.1 - 0.074 12.6 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KIK63651.1 - 0.092 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIK63651.1 - 0.15 12.0 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SF1-HH PF16275.5 KIK63654.1 - 6.2e-39 132.8 1.9 1.3e-38 131.8 1.9 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KIK63654.1 - 1e-11 44.3 8.9 1.4e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KIK63654.1 - 1e-06 28.6 3.6 0.0026 17.7 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KIK63654.1 - 9.5e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 KIK63654.1 - 0.0017 18.2 7.9 0.24 11.2 1.1 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KIK63654.1 - 0.0049 16.6 7.1 0.4 10.4 0.6 2.5 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 KIK63654.1 - 0.019 15.3 2.4 4.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DnaJ_CXXCXGXG PF00684.19 KIK63654.1 - 0.17 12.3 4.5 0.37 11.2 4.5 1.5 1 0 0 1 1 1 0 DnaJ central domain Prim_Zn_Ribbon PF08273.12 KIK63654.1 - 0.25 11.7 3.6 0.55 10.6 3.6 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-CCHC_2 PF13696.6 KIK63654.1 - 3.5 7.5 9.8 0.35 10.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Aldo_ket_red PF00248.21 KIK63655.1 - 1.7e-68 231.0 0.0 2e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GIIM PF08388.11 KIK63655.1 - 0.042 13.9 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Group II intron, maturase-specific domain Cyto_heme_lyase PF01265.17 KIK63656.1 - 6.5e-48 163.8 8.3 2.7e-46 158.5 8.3 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.15 KIK63657.1 - 3.9e-45 154.7 0.6 6.7e-45 153.9 0.6 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK63657.1 - 2e-07 30.3 0.3 3.9e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK63657.1 - 0.021 13.9 3.2 0.033 13.2 3.2 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glyco_hydro_3 PF00933.21 KIK63658.1 - 4.1e-47 161.1 0.0 5.4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIK63658.1 - 3.1e-46 157.9 0.0 9.1e-46 156.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIK63658.1 - 2.3e-23 82.0 0.5 6e-23 80.7 0.5 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 KIK63658.1 - 0.0061 16.8 2.5 0.02 15.2 2.1 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.11 KIK63658.1 - 0.092 13.0 1.5 0.22 11.8 0.8 1.9 2 0 0 2 2 2 0 CARDB Glyco_hydro_3 PF00933.21 KIK63662.1 - 6.6e-44 150.6 0.0 9.7e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIK63662.1 - 3.6e-43 147.9 0.0 5.4e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIK63662.1 - 7.1e-13 48.5 0.1 1.4e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIK63662.1 - 1.5e-10 41.0 0.0 4.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KIK63662.1 - 0.025 14.8 0.8 0.51 10.6 0.3 2.5 2 0 0 2 2 2 0 CARDB DUF3738 PF12543.8 KIK63662.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Sugar_tr PF00083.24 KIK63663.1 - 3.1e-75 253.8 20.4 3.9e-75 253.4 20.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63663.1 - 6.7e-38 130.5 37.0 6.6e-30 104.2 18.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 KIK63663.1 - 1.9 8.0 8.4 0.17 11.4 0.2 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family DUF1358 PF07096.11 KIK63663.1 - 6.9 6.7 6.8 2.9 7.9 1.5 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1358) WD40 PF00400.32 KIK63664.1 - 3.5e-14 52.9 10.3 1.6e-05 25.5 0.1 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat ADH_zinc_N PF00107.26 KIK63665.1 - 2e-29 102.2 0.1 3.4e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK63665.1 - 5.7e-19 69.5 0.0 1.2e-18 68.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK63665.1 - 2.5e-07 30.5 0.2 1.1e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIK63665.1 - 0.088 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PPTA PF01239.22 KIK63666.1 - 9.6e-45 149.1 16.8 2.4e-08 33.5 0.1 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 KIK63666.1 - 0.014 15.7 0.1 9 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MetW PF07021.12 KIK63666.1 - 0.037 13.6 0.1 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DUF3950 PF13132.6 KIK63666.1 - 1.2 9.0 4.3 40 4.1 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) TPR_14 PF13428.6 KIK63667.1 - 4.1e-10 39.6 12.1 1.8 9.6 0.0 11.4 10 4 4 14 14 13 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63667.1 - 4.8e-07 29.4 9.7 0.065 13.4 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK63667.1 - 1.7e-06 28.4 0.9 0.45 11.1 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63667.1 - 0.00014 22.1 7.1 0.91 9.9 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.14 KIK63667.1 - 0.0032 17.5 4.2 0.0032 17.5 4.2 4.7 4 1 0 5 5 5 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KIK63667.1 - 0.005 16.8 13.8 4.1 7.4 0.1 6.3 8 0 0 8 8 8 1 Mad3/BUB1 homology region 1 MIT PF04212.18 KIK63667.1 - 0.021 14.9 0.4 0.39 10.8 0.1 3.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain NRDE-2 PF08424.10 KIK63667.1 - 0.032 13.4 13.8 0.37 9.9 0.1 5.8 4 1 1 6 6 6 0 NRDE-2, necessary for RNA interference CEP209_CC5 PF16574.5 KIK63667.1 - 0.1 12.8 0.7 0.41 10.8 0.5 2.1 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 TPR_1 PF00515.28 KIK63667.1 - 0.21 11.5 4.9 61 3.7 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HAT PF02184.16 KIK63667.1 - 2.2 8.3 13.4 2.4 8.2 0.2 6.2 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat CK2S PF15011.6 KIK63668.1 - 0.088 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate G-alpha PF00503.20 KIK63668.1 - 0.096 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit HSBP1 PF06825.12 KIK63668.1 - 0.22 11.4 0.6 1.1 9.1 0.2 2.2 1 1 1 2 2 2 0 Heat shock factor binding protein 1 NTP_transferase PF00483.23 KIK63669.1 - 5.1e-09 36.1 0.0 9.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KIK63669.1 - 1.1e-08 34.4 2.5 0.00078 19.1 0.3 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KIK63669.1 - 2.5e-06 27.9 0.0 3.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KIK63669.1 - 0.0098 14.1 1.0 0.026 12.7 0.5 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KIK63669.1 - 0.074 12.0 0.6 0.2 10.6 0.4 1.6 1 1 1 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 KIK63669.1 - 0.37 10.6 4.5 1.3 8.8 1.4 2.5 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 KIK63671.1 - 5.8e-63 212.7 0.0 6.7e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63671.1 - 5.7e-48 163.4 0.0 7.1e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK63671.1 - 2.8e-05 23.1 0.0 4.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK63671.1 - 0.00037 20.5 0.0 1.4 8.8 0.0 2.6 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK63671.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK63671.1 - 0.013 14.4 0.0 0.031 13.2 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIK63671.1 - 0.019 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIK63671.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ResIII PF04851.15 KIK63672.1 - 4.3e-22 78.9 0.0 1.7e-21 77.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK63672.1 - 5e-18 65.5 0.0 1.4e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63672.1 - 4.6e-17 62.4 0.2 2.2e-16 60.2 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK63672.1 - 0.00056 19.2 0.5 0.0022 17.3 0.4 1.9 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 KIK63672.1 - 0.0022 17.3 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KIK63672.1 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KIK63672.1 - 0.025 14.8 0.0 0.12 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.7 KIK63674.1 - 0.0046 17.3 0.5 34 5.0 0.0 4.4 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) STAR_dimer PF16544.5 KIK63674.1 - 0.18 11.4 1.4 0.73 9.5 0.1 2.6 2 1 0 2 2 2 0 Homodimerisation region of STAR domain protein Cyclin_N PF00134.23 KIK63676.1 - 1.4e-05 24.9 0.1 2.3e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK63676.1 - 0.013 15.9 0.1 0.017 15.5 0.1 1.2 1 0 0 1 1 1 0 Cyclin DUF1748 PF08520.10 KIK63676.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Skp1 PF01466.19 KIK63677.1 - 1e-26 92.7 1.2 1e-26 92.7 1.2 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK63677.1 - 2.2e-23 82.2 0.5 5.4e-23 80.9 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain RT_RNaseH_2 PF17919.1 KIK63682.1 - 0.00046 20.2 0.0 0.00063 19.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Galanin PF01296.18 KIK63684.1 - 0.16 12.0 0.5 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Galanin s48_45 PF07422.13 KIK63685.1 - 0.034 14.7 0.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain Zn_clus PF00172.18 KIK63688.1 - 4.7e-08 33.0 24.4 7.2e-06 26.0 8.2 3.3 2 1 1 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4620 PF15399.6 KIK63688.1 - 0.047 14.0 0.6 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) TerY_C PF15616.6 KIK63688.1 - 4.2 7.5 14.6 1.3 9.1 3.7 2.4 1 1 1 2 2 2 0 TerY-C metal binding domain ANAPC4_WD40 PF12894.7 KIK63689.1 - 0.0036 17.6 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Seryl_tRNA_N PF02403.22 KIK63689.1 - 1.2 9.4 4.7 2.6 8.3 4.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Peptidase_C78 PF07910.13 KIK63690.1 - 7.5e-38 130.1 0.0 1.9e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family C78 Proteasome PF00227.26 KIK63691.1 - 1.6e-60 203.9 0.0 2.2e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK63691.1 - 4.4e-14 51.8 0.1 1.1e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Orthopox_B11R PF07033.11 KIK63691.1 - 0.14 11.9 0.4 2.7 7.8 0.4 2.5 2 0 0 2 2 2 0 Orthopoxvirus B11R protein LigB PF02900.18 KIK63692.1 - 3e-39 134.7 0.0 3.6e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF4910 PF16254.5 KIK63692.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) MAT1 PF06391.13 KIK63693.1 - 3.8e-57 193.4 12.8 5e-57 193.0 12.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KIK63693.1 - 4.9e-24 84.0 7.9 9.4e-24 83.1 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK63693.1 - 0.00012 21.8 3.0 0.00028 20.7 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK63693.1 - 0.00021 21.1 4.4 0.00037 20.3 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK63693.1 - 0.0004 20.2 4.8 0.00083 19.1 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK63693.1 - 0.00073 19.5 6.6 0.0025 17.7 6.9 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK63693.1 - 0.002 18.4 6.6 0.0033 17.7 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK63693.1 - 0.027 14.5 6.1 0.051 13.6 6.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KIK63693.1 - 0.29 10.9 3.4 2.1 8.2 1.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Smg8_Smg9 PF10220.9 KIK63693.1 - 0.68 8.2 4.8 0.88 7.8 4.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 UPF0242 PF06785.11 KIK63693.1 - 1 9.4 11.5 1.9 8.6 11.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1682 PF07946.14 KIK63693.1 - 4.3 6.4 12.6 6.1 5.9 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3797 PF12677.7 KIK63693.1 - 8.4 6.4 7.2 0.37 10.7 1.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) MFS_1 PF07690.16 KIK63694.1 - 4.5e-34 117.9 29.5 4.5e-34 117.9 29.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily COX2-transmemb PF09125.10 KIK63694.1 - 0.14 12.0 4.6 0.66 9.8 4.6 2.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Pkinase PF00069.25 KIK63696.1 - 4.6e-66 222.9 0.0 6.1e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63696.1 - 2.6e-31 108.9 0.0 3.3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK63696.1 - 0.00019 20.9 0.0 0.00046 19.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK63696.1 - 0.016 15.1 0.1 5.3 6.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Piwi PF02171.17 KIK63698.1 - 1.5e-64 218.2 0.0 2.5e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Piwi domain Brix PF04427.18 KIK63698.1 - 2.6e-44 151.7 0.0 5.4e-44 150.6 0.0 1.6 1 0 0 1 1 1 1 Brix domain ArgoL1 PF08699.10 KIK63698.1 - 1.3e-12 47.1 0.0 3.6e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KIK63698.1 - 6.4e-07 30.1 0.0 5e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 N-terminal domain of argonaute PAZ PF02170.22 KIK63698.1 - 3.1e-06 27.0 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KIK63698.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK63698.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute Cwf_Cwc_15 PF04889.12 KIK63698.1 - 3.3 7.4 19.1 7.1 6.3 19.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 KIK63698.1 - 8.5 6.8 18.3 18 5.8 18.3 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Brix PF04427.18 KIK63699.1 - 3.6e-45 154.5 0.0 4.8e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Cwf_Cwc_15 PF04889.12 KIK63699.1 - 0.21 11.3 21.0 0.43 10.3 21.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMEM214 PF10151.9 KIK63699.1 - 0.6 8.5 2.8 0.86 8.0 2.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Sec7 PF01369.20 KIK63700.1 - 1.7e-68 230.0 0.0 2.9e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KIK63700.1 - 2.9e-19 69.5 0.3 2.1e-18 66.7 0.0 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIK63700.1 - 0.00022 21.0 1.5 0.93 9.4 0.1 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Cytochrom_B561 PF03188.16 KIK63701.1 - 2e-13 50.7 6.0 4.1e-13 49.6 6.0 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KIK63701.1 - 0.15 12.2 8.6 0.15 12.3 4.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF202 PF02656.15 KIK63701.1 - 0.88 10.1 10.1 7.5 7.1 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF2231 PF09990.9 KIK63701.1 - 2 8.9 10.3 1.3 9.5 5.9 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF4395 PF14340.6 KIK63701.1 - 3.5 8.0 9.3 0.71 10.2 5.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Epimerase PF01370.21 KIK63702.1 - 0.039 13.4 0.0 0.13 11.7 0.0 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KIK63703.1 - 5.5e-35 120.9 0.0 8.3e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIK63703.1 - 9.1e-31 106.6 0.0 1.6e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KIK63703.1 - 0.0052 17.3 0.0 0.019 15.5 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-CCCH PF00642.24 KIK63704.1 - 2.3e-09 36.9 2.7 4.8e-09 35.9 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KIK63704.1 - 3.5e-08 33.2 4.8 6.2e-08 32.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK63704.1 - 3e-07 30.3 8.0 5.2e-07 29.5 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK63704.1 - 2.8e-06 27.3 9.0 5.4e-06 26.3 9.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK63704.1 - 1.3e-05 25.0 8.7 2.4e-05 24.1 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KIK63704.1 - 1.3e-05 25.1 4.4 3e-05 23.9 4.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KIK63704.1 - 3e-05 23.8 9.6 6e-05 22.8 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK63704.1 - 9.4e-05 22.7 6.9 0.00018 21.7 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 KIK63704.1 - 0.00023 21.3 2.6 0.00023 21.3 2.6 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 KIK63704.1 - 0.0015 18.3 2.9 0.003 17.3 2.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KIK63704.1 - 0.0023 18.0 7.3 0.0053 16.9 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIK63704.1 - 0.02 14.7 6.7 0.039 13.8 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIK63704.1 - 0.19 11.6 2.2 0.39 10.6 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_2 PF03107.16 KIK63704.1 - 2.1 8.8 6.7 6.5 7.2 5.0 2.3 1 1 1 2 2 2 0 C1 domain zf-RanBP PF00641.18 KIK63704.1 - 2.6 7.5 7.8 0.059 12.7 1.2 1.8 2 0 0 2 2 1 0 Zn-finger in Ran binding protein and others Ribosomal_L15e PF00827.17 KIK63705.1 - 2e-90 301.7 9.9 2.3e-90 301.4 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 BTB PF00651.31 KIK63706.1 - 0.00046 20.4 0.0 0.00077 19.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIK63707.1 - 0.0037 17.5 0.0 0.0064 16.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain C2 PF00168.30 KIK63709.1 - 2e-07 31.2 0.0 3.3e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 C2 domain AAA_12 PF13087.6 KIK63710.1 - 1e-17 64.4 0.3 3e-16 59.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK63710.1 - 7.2e-13 48.9 1.2 1.1e-09 38.5 0.0 2.9 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 KIK63710.1 - 4.9e-12 46.0 0.0 9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK63710.1 - 3.2e-09 37.3 0.0 7.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK63710.1 - 8.3e-05 23.0 0.0 0.00038 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 KIK63710.1 - 0.0016 17.7 0.6 0.24 10.6 0.0 3.1 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KIK63710.1 - 0.0042 17.1 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KIK63710.1 - 0.0083 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK63710.1 - 0.016 15.4 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK63710.1 - 0.055 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KIK63710.1 - 0.17 11.2 0.0 0.44 9.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Metallophos PF00149.28 KIK63711.1 - 1.3e-12 48.7 0.0 1.7e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK63711.1 - 1.5e-07 31.8 0.0 1.4e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KIK63711.1 - 0.034 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily SPT16 PF08644.11 KIK63712.1 - 4.9e-53 179.4 0.2 2.9e-52 176.9 0.0 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KIK63712.1 - 3.7e-43 147.1 0.0 1.1e-42 145.5 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KIK63712.1 - 7.7e-22 78.0 0.0 1.3e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KIK63712.1 - 6.1e-16 58.6 0.6 2.8e-14 53.3 0.0 2.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like YL1 PF05764.13 KIK63712.1 - 0.097 12.8 28.4 1.6 8.8 0.1 3.3 3 0 0 3 3 3 0 YL1 nuclear protein DUF3956 PF13104.6 KIK63712.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) HTH_9 PF08221.11 KIK63714.1 - 2.6e-22 78.7 4.9 8.3e-17 61.1 0.7 3.7 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KIK63714.1 - 6.7e-16 58.8 0.8 4.3e-14 52.9 0.2 2.9 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 KIK63714.1 - 5.9e-09 35.7 0.1 5e-05 23.1 0.0 3.6 4 0 0 4 4 4 2 TFIIE alpha subunit Pkinase_Tyr PF07714.17 KIK63716.1 - 1.6e-35 122.7 0.0 1.9e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK63716.1 - 3.4e-28 98.7 0.0 4.1e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK63716.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK63716.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RTA1 PF04479.13 KIK63717.1 - 1.2e-48 165.5 6.1 2.5e-47 161.2 6.1 2.1 1 1 0 1 1 1 1 RTA1 like protein PmbA_TldD PF01523.16 KIK63717.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase COX4 PF02936.14 KIK63718.1 - 6.1e-40 136.4 0.0 8.3e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Gly-rich_Ago1 PF12764.7 KIK63718.1 - 0.09 13.6 1.4 0.16 12.7 1.4 1.4 1 0 0 1 1 1 0 Glycine-rich region of argonaut zf-CCHC PF00098.23 KIK63719.1 - 1.5e-07 31.1 6.9 6.4e-07 29.2 2.1 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIK63719.1 - 0.023 14.4 1.0 0.043 13.5 1.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Ig_J_chain PF15097.6 KIK63719.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin J chain zf-CCHC_2 PF13696.6 KIK63719.1 - 2 8.3 6.2 0.62 10.0 1.1 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF3445 PF11927.8 KIK63722.1 - 2.4e-75 253.0 0.0 3.1e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Abhydrolase_1 PF00561.20 KIK63724.1 - 2.3e-18 66.8 0.0 6.6e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK63724.1 - 4.3e-14 53.6 0.0 5.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK63724.1 - 3.6e-10 39.5 0.0 5.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIK63724.1 - 0.0062 16.4 0.1 0.045 13.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIK63724.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 KIK63724.1 - 0.024 14.1 0.1 0.58 9.6 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KIK63724.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain MTCP1 PF08991.10 KIK63725.1 - 7.9e-17 61.2 6.6 8.5e-17 61.1 6.6 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type DSPc PF00782.20 KIK63727.1 - 3.5e-38 130.4 0.0 1.1e-31 109.4 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK63727.1 - 0.0047 17.2 0.0 0.073 13.4 0.0 2.4 2 1 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIK63727.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Abhydrolase_6 PF12697.7 KIK63727.1 - 0.16 12.5 0.2 0.75 10.4 0.0 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family Tim17 PF02466.19 KIK63728.1 - 9.3e-30 103.3 9.9 9.3e-30 103.3 9.9 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 KIK63728.1 - 0.072 13.2 9.6 2.2 8.5 2.7 2.9 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III PsaL PF02605.15 KIK63728.1 - 0.57 9.8 3.5 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI RNA12 PF10443.9 KIK63729.1 - 4.3e-117 391.5 1.8 6.1e-65 219.7 2.5 2.2 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 KIK63729.1 - 5.4e-06 26.5 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIK63729.1 - 5.6e-05 23.6 1.2 5.6e-05 23.6 1.2 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK63729.1 - 0.0021 18.3 0.1 0.009 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KIK63729.1 - 0.0024 17.7 2.7 0.0035 17.2 0.7 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KIK63729.1 - 0.0026 17.4 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIK63729.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK63729.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.22 KIK63729.1 - 0.017 15.0 0.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_18 PF13238.6 KIK63729.1 - 0.018 15.6 0.1 17 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KIK63729.1 - 0.021 14.6 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KIK63729.1 - 0.031 14.7 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK63729.1 - 0.035 14.6 0.1 0.14 12.7 0.1 2.1 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KIK63729.1 - 0.036 14.0 1.6 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 KIK63729.1 - 0.039 14.1 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK63729.1 - 0.079 12.1 0.0 0.22 10.7 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain baeRF_family10 PF18854.1 KIK63729.1 - 0.093 13.0 0.2 0.43 10.8 0.2 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 AAA_7 PF12775.7 KIK63729.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KIK63729.1 - 0.93 10.0 0.0 0.93 10.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain Tubulin PF00091.25 KIK63730.1 - 1.4e-70 237.5 0.0 2.7e-70 236.6 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK63730.1 - 4.3e-46 156.2 0.5 8.4e-46 155.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIK63730.1 - 0.0016 18.7 0.0 0.0056 17.0 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KIK63730.1 - 0.037 13.2 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 KIK63730.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Hrs_helical PF12210.8 KIK63730.1 - 0.082 13.5 0.2 0.18 12.3 0.2 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MBF1 PF08523.10 KIK63731.1 - 1.5e-26 92.6 3.9 2.6e-26 91.9 3.9 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KIK63731.1 - 6.9e-14 51.6 0.1 1.1e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIK63731.1 - 2e-06 28.1 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIK63731.1 - 3.1e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIK63731.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Tetraspanin PF00335.20 KIK63732.1 - 1e-06 28.7 13.4 1.5e-06 28.1 13.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DEAD PF00270.29 KIK63733.1 - 1.1e-21 77.4 0.0 1.9e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KIK63733.1 - 5.2e-14 52.8 1.0 2.9e-13 50.4 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KIK63733.1 - 4.4e-13 49.6 0.2 8.2e-12 45.4 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63733.1 - 2.1e-07 31.1 0.1 1.2e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KIK63733.1 - 8.5e-07 29.4 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like Pkinase PF00069.25 KIK63734.1 - 1.9e-22 79.9 0.0 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63734.1 - 3e-12 46.4 0.0 7.2e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5578 PF17741.1 KIK63734.1 - 0.22 10.9 0.9 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5578) DUF2420 PF10336.9 KIK63735.1 - 2.1e-07 30.9 0.7 4.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) NIPSNAP PF07978.13 KIK63736.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 NIPSNAP Ctr PF04145.15 KIK63737.1 - 5.5e-39 134.1 1.3 6.8e-39 133.8 1.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Cation_ATPase_C PF00689.21 KIK63737.1 - 2 8.1 7.9 1.3 8.7 1.2 2.1 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus CPBP PF02517.16 KIK63737.1 - 6.2 7.3 7.6 0.85 10.0 0.3 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease 5_nucleotid_C PF02872.18 KIK63739.1 - 6.2e-24 85.0 0.0 1.1e-23 84.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIK63739.1 - 1.4e-06 29.0 0.2 2.4e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S15 PF00312.22 KIK63740.1 - 3.2e-23 81.7 0.3 6.5e-23 80.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 ERCC3_RAD25_C PF16203.5 KIK63741.1 - 7e-124 411.9 0.5 1.5e-123 410.8 0.1 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KIK63741.1 - 1.2e-38 132.1 0.0 2.8e-38 130.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63741.1 - 7.4e-16 58.6 0.0 1.4e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK63741.1 - 2.3e-11 44.0 0.0 7e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIK63741.1 - 6.6e-09 35.0 0.0 1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KIK63741.1 - 5.2e-05 23.1 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cas_Csm6 PF09659.10 KIK63741.1 - 0.019 13.8 1.3 0.48 9.2 0.8 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) Glyco_hydro_38N PF01074.22 KIK63743.1 - 4.3e-79 265.9 1.1 6.3e-79 265.3 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KIK63743.1 - 4e-50 170.9 0.0 7e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KIK63743.1 - 2.9e-27 94.6 0.0 5.9e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KIK63743.1 - 0.0011 19.0 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Apolipoprotein PF01442.18 KIK63744.1 - 0.05 13.5 21.2 8.5 6.2 18.8 3.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KIK63744.1 - 0.13 12.3 15.0 0.065 13.3 3.7 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SIC PF03482.13 KIK63744.1 - 0.17 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 sic protein repeat DUF148 PF02520.17 KIK63744.1 - 1.1 9.4 13.9 0.28 11.3 1.3 3.2 1 1 2 3 3 3 0 Domain of unknown function DUF148 Mobilization_B PF17511.2 KIK63744.1 - 5.8 7.3 8.5 0.37 11.1 1.4 2.3 1 1 0 2 2 2 0 Mobilization protein B Mpv17_PMP22 PF04117.12 KIK63745.1 - 4.8e-21 74.7 1.9 1.6e-20 73.1 0.2 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1275 PF06912.11 KIK63746.1 - 4e-25 88.9 10.8 4.6e-25 88.7 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Methyltransf_16 PF10294.9 KIK63747.1 - 1.1e-18 67.6 0.0 1.9e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK63747.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK63747.1 - 0.0054 16.2 0.0 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KIK63747.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KIK63747.1 - 0.051 14.3 0.0 0.39 11.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Orai-1 PF07856.12 KIK63750.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity Mito_fiss_reg PF05308.11 KIK63751.1 - 3.3 7.7 8.5 4.7 7.2 8.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator T2SSM PF04612.12 KIK63752.1 - 0.047 13.8 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Maf PF02545.14 KIK63753.1 - 1.3e-44 152.0 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein TPR_11 PF13414.6 KIK63753.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 TPR repeat Peptidase_S28 PF05577.12 KIK63754.1 - 6.4e-52 176.8 5.4 1.4e-34 119.7 1.9 3.0 2 1 0 2 2 2 2 Serine carboxypeptidase S28 DUF974 PF06159.13 KIK63755.1 - 2.1e-80 270.1 0.0 3e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) S1-P1_nuclease PF02265.16 KIK63756.1 - 1.1e-45 156.4 0.0 1.1e-41 143.3 0.0 2.8 1 1 1 2 2 2 2 S1/P1 Nuclease Endonuclease_NS PF01223.23 KIK63757.1 - 9.4e-58 195.7 0.0 1.1e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PHD20L1_u1 PF16660.5 KIK63757.1 - 0.14 12.9 1.0 33 5.3 0.0 3.3 4 0 0 4 4 4 0 PHD finger protein 20-like protein 1 MRP-L46 PF11788.8 KIK63758.1 - 6.8e-19 68.8 0.1 2.1e-18 67.2 0.1 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KIK63758.1 - 2.1e-07 31.0 0.1 5.5e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain V-ATPase_H_N PF03224.14 KIK63759.1 - 4.9e-88 295.5 0.1 8e-88 294.7 0.1 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KIK63759.1 - 6.2e-45 152.1 1.3 1.6e-43 147.5 0.1 2.7 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 KIK63759.1 - 1e-05 25.2 0.0 2.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 KIK63759.1 - 0.00065 19.7 0.1 8.3 6.6 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KIK63759.1 - 0.0025 18.2 1.4 0.018 15.5 0.0 3.1 3 1 1 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 KIK63759.1 - 0.034 12.7 1.1 1 7.9 1.1 3.1 1 1 0 1 1 1 0 Adaptin N terminal region HEAT PF02985.22 KIK63759.1 - 0.036 14.3 0.7 0.68 10.4 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat RTP1_C1 PF10363.9 KIK63759.1 - 0.057 13.6 0.3 1.8 8.8 0.0 3.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 FMN_dh PF01070.18 KIK63760.1 - 2.7e-103 345.7 0.0 4.4e-103 345.0 0.0 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KIK63760.1 - 1.1e-05 25.0 0.2 1.7e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KIK63760.1 - 3.7e-05 23.0 0.1 5.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIK63760.1 - 0.00028 20.0 0.3 0.0004 19.5 0.3 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KIK63760.1 - 0.0022 17.4 0.5 0.064 12.6 0.3 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KIK63760.1 - 0.0023 17.2 0.2 0.0048 16.1 0.1 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KIK63760.1 - 0.043 13.3 0.6 1 8.8 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein His_Phos_2 PF00328.22 KIK63761.1 - 1.8e-45 155.9 0.0 2.2e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EF-hand_4 PF12763.7 KIK63762.1 - 1.6e-33 114.8 0.0 2.1e-13 50.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KIK63762.1 - 4.4e-06 27.0 0.0 0.0076 16.7 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 KIK63762.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 KIK63762.1 - 0.0023 17.7 1.5 6.1 7.1 0.0 5.0 6 0 0 6 6 6 1 EF-hand domain EF-hand_1 PF00036.32 KIK63762.1 - 0.016 14.7 0.5 0.87 9.3 0.0 3.8 5 0 0 5 5 5 0 EF hand UBA_3 PF09288.10 KIK63762.1 - 0.084 12.7 0.5 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain WEMBL PF05701.11 KIK63762.1 - 1.6 7.4 40.3 2.4 6.8 40.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Macoilin PF09726.9 KIK63762.1 - 2.2 6.8 22.4 3.8 5.9 22.4 1.3 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 KIK63762.1 - 6.2 7.2 33.0 0.42 11.1 21.5 2.3 1 1 1 2 2 2 0 Fez1 UQ_con PF00179.26 KIK63763.1 - 5.8e-44 149.1 0.0 7.1e-44 148.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK63763.1 - 1.3e-05 25.5 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIK63763.1 - 0.0027 17.4 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B R3H PF01424.22 KIK63765.1 - 3.5e-11 42.9 0.1 7.1e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KIK63765.1 - 3e-07 30.1 0.1 7e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 KIK63767.1 - 5.8e-48 163.0 0.0 1e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63767.1 - 3.7e-23 82.0 0.0 2e-22 79.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIK63767.1 - 4.4e-21 74.9 0.0 9.2e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIK63767.1 - 8.3e-06 25.9 0.0 5.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ddrB-ParB PF18763.1 KIK63767.1 - 0.0025 17.9 0.1 0.41 10.7 0.0 2.8 2 1 0 2 2 2 1 ddrB-like ParB superfamily domain PDEase_II PF02112.15 KIK63768.1 - 1.9e-33 116.0 0.0 7.7e-33 114.0 0.0 1.9 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KIK63768.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK63768.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Striatin PF08232.12 KIK63769.1 - 1.4e-50 171.9 0.0 1.4e-50 171.9 0.0 3.1 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 KIK63769.1 - 4.6e-38 128.5 11.7 8.5e-07 29.6 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK63769.1 - 1.2e-10 41.5 0.1 0.056 13.8 0.0 5.6 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 KIK63769.1 - 5.1e-05 23.4 29.4 0.00049 20.2 20.2 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nucleoporin_N PF08801.11 KIK63769.1 - 0.00018 20.4 0.1 0.027 13.2 0.0 3.2 2 1 1 3 3 3 1 Nup133 N terminal like Spt20 PF12090.8 KIK63769.1 - 0.0024 17.5 22.5 0.0024 17.5 22.5 2.3 2 0 0 2 2 2 1 Spt20 family Nup160 PF11715.8 KIK63769.1 - 0.0026 16.5 0.2 1.2 7.7 0.0 3.0 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nucleo_P87 PF07267.11 KIK63769.1 - 0.13 11.1 16.1 0.2 10.4 16.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Vasculin PF15337.6 KIK63769.1 - 2.3 9.1 11.8 32 5.4 8.3 2.7 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 GREB1 PF15782.5 KIK63769.1 - 5.7 3.9 10.7 8.9 3.3 10.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMA7 PF09072.10 KIK63770.1 - 7.7e-22 77.9 24.2 8.4e-22 77.8 24.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Peptidase_S9 PF00326.21 KIK63771.1 - 0.0001 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIK63771.1 - 0.00033 20.4 0.0 0.0007 19.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold 3HBOH PF10605.9 KIK63771.1 - 0.0031 15.8 0.0 0.0046 15.3 0.0 1.1 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) Tannase PF07519.11 KIK63771.1 - 0.0078 15.2 0.1 0.35 9.7 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KIK63771.1 - 0.0086 15.4 0.0 0.025 13.9 0.0 1.6 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIK63771.1 - 0.0087 15.7 1.3 0.03 13.9 1.3 1.9 1 1 0 1 1 1 1 Putative esterase ApbA PF02558.16 KIK63772.1 - 2.7e-18 66.0 0.0 4.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIK63772.1 - 1.2e-15 57.8 0.0 6.9e-14 52.1 0.0 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 KIK63772.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Not1 PF04054.15 KIK63773.1 - 7.9e-128 426.4 0.4 1.9e-127 425.2 0.4 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KIK63773.1 - 2.2e-91 305.3 1.0 8.2e-89 296.8 0.0 2.7 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KIK63773.1 - 1.7e-54 183.8 1.0 3.6e-54 182.7 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KIK63773.1 - 5.6e-51 172.4 0.0 1.3e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KIK63773.1 - 6.7e-46 156.1 0.2 1.9e-45 154.6 0.2 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat HOOK PF05622.12 KIK63774.1 - 2.1e-59 201.4 47.3 2.1e-59 201.4 47.3 2.2 1 1 1 2 2 2 1 HOOK protein HMMR_N PF15905.5 KIK63774.1 - 0.0015 18.1 19.1 0.0015 18.1 19.1 5.8 2 2 3 6 6 6 1 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 KIK63774.1 - 0.01 15.9 6.1 0.01 15.9 6.1 9.2 8 1 1 10 10 10 0 bZIP transcription factor T3SSipB PF16535.5 KIK63774.1 - 0.013 16.0 2.6 0.013 16.0 2.6 4.2 3 1 1 4 4 4 0 Type III cell invasion protein SipB HIP1_clath_bdg PF16515.5 KIK63774.1 - 0.014 16.0 8.3 0.014 16.0 8.3 8.2 3 2 6 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dam1 PF08653.10 KIK63774.1 - 3.2 7.6 5.9 14 5.5 0.2 4.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 RTC PF01137.21 KIK63775.1 - 6.8e-80 267.4 0.1 7.9e-80 267.2 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIK63775.1 - 9.6e-28 96.7 0.1 1.8e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3247 PF11607.8 KIK63776.1 - 0.041 14.1 0.2 0.097 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) adh_short PF00106.25 KIK63777.1 - 4.9e-26 91.4 0.0 9.1e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK63777.1 - 3.9e-12 46.2 0.0 1.1e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK63777.1 - 1.1e-08 35.3 0.0 2.4e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK63777.1 - 7.1e-06 25.7 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK63777.1 - 0.00048 19.6 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK63777.1 - 0.0013 17.9 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KIK63777.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK63777.1 - 0.0024 18.1 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KIK63777.1 - 0.022 13.9 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 KIK63777.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIK63777.1 - 0.097 13.3 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PGM_PMM_I PF02878.16 KIK63778.1 - 4.7e-39 133.3 0.0 8.7e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KIK63778.1 - 6.4e-20 71.7 0.0 2.1e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIK63778.1 - 3.7e-18 65.8 0.1 1.1e-17 64.3 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Transferase PF02458.15 KIK63778.1 - 3.6e-06 25.9 0.0 6.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Transferase family PGM_PMM_IV PF00408.20 KIK63778.1 - 4.5e-05 23.6 0.1 0.00012 22.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Alpha-amylase PF00128.24 KIK63779.1 - 1.8e-46 159.2 0.0 5.2e-46 157.8 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIK63779.1 - 2.1e-10 40.7 0.3 5.5e-10 39.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Phage_Coat_B PF05356.11 KIK63779.1 - 0.037 13.9 0.2 4.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Phage Coat protein B Sugar_tr PF00083.24 KIK63780.1 - 1.1e-78 265.2 13.2 1.4e-78 264.8 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63780.1 - 9.5e-15 54.4 30.9 9.5e-15 54.4 30.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK63780.1 - 0.051 12.9 19.4 0.18 11.1 11.7 3.2 1 1 2 3 3 3 0 Uncharacterised MFS-type transporter YbfB DUF4436 PF14494.6 KIK63780.1 - 0.35 10.1 5.5 0.14 11.4 3.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) Pkinase PF00069.25 KIK63781.1 - 9e-33 113.7 0.0 1.8e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63781.1 - 2.7e-21 76.0 0.0 4.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK63781.1 - 0.00011 21.7 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 KIK63781.1 - 0.00036 20.8 0.1 0.0011 19.3 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Lebercilin PF15619.6 KIK63782.1 - 0.022 14.4 3.8 0.037 13.7 3.8 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KIK63782.1 - 0.053 13.0 2.8 0.092 12.2 2.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 FAM76 PF16046.5 KIK63782.1 - 0.1 11.9 0.1 0.1 11.9 0.1 1.8 2 0 0 2 2 2 0 FAM76 protein PKcGMP_CC PF16808.5 KIK63782.1 - 0.54 10.2 9.6 0.66 9.9 1.7 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MFS_1 PF07690.16 KIK63783.1 - 5.2e-17 61.8 79.5 2e-15 56.6 40.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK63783.1 - 0.042 13.2 22.7 0.059 12.7 22.7 1.2 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB PBP PF01161.20 KIK63784.1 - 6.1e-25 88.1 0.0 2.5e-11 44.0 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylethanolamine-binding protein SUR7 PF06687.12 KIK63785.1 - 1.3e-12 47.9 4.7 2.7e-12 46.8 4.7 1.4 1 1 0 1 1 1 1 SUR7/PalI family TPPK_C PF12555.8 KIK63785.1 - 2.6 8.2 10.0 4.6 7.4 0.6 2.9 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal PrgI PF12666.7 KIK63785.1 - 4.9 7.9 7.4 0.43 11.3 0.9 2.4 2 1 1 3 3 3 0 PrgI family protein Mito_carr PF00153.27 KIK63787.1 - 6.5e-66 218.3 2.9 1.6e-23 82.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rbc25 PF08292.12 KIK63788.1 - 5e-32 110.9 0.0 7.9e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KIK63788.1 - 9.8e-21 73.9 0.0 1.6e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MOR2-PAG1_N PF14222.6 KIK63789.1 - 3.6e-168 561.0 0.2 3.6e-168 561.0 0.2 1.9 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KIK63789.1 - 2.9e-86 289.4 2.2 2.9e-86 289.4 2.2 2.9 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KIK63789.1 - 5.8e-17 60.7 1.6 6.7e-11 40.6 0.1 3.2 3 0 0 3 3 3 3 Cell morphogenesis central region SPO22 PF08631.10 KIK63789.1 - 0.021 14.3 1.2 3.3 7.1 0.1 3.1 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like PikAIV_N PF18605.1 KIK63791.1 - 0.37 10.4 13.5 9.3 5.9 0.6 3.3 1 1 2 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain COMP PF11598.8 KIK63791.1 - 0.37 11.3 1.9 37 4.9 0.0 3.1 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein PHD PF00628.29 KIK63792.1 - 1.6e-06 27.9 8.0 2.5e-06 27.3 8.0 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KIK63792.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KIK63792.1 - 0.0031 17.7 1.4 0.0057 16.9 1.4 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KIK63792.1 - 0.0086 15.6 2.0 0.016 14.7 2.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KIK63792.1 - 0.01 16.0 1.0 0.018 15.2 1.0 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain SUD-M PF11633.8 KIK63792.1 - 0.046 13.4 0.0 1.7 8.4 0.0 2.7 3 0 0 3 3 3 0 Single-stranded poly(A) binding domain FANCL_C PF11793.8 KIK63792.1 - 0.083 13.1 1.1 0.18 12.0 1.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain AMP-binding PF00501.28 KIK63793.1 - 1.2e-86 291.0 0.0 1.7e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK63793.1 - 2.1e-09 38.2 0.4 4.8e-09 37.1 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IPPT PF01715.17 KIK63795.1 - 5.4e-54 183.4 0.0 6.4e-53 179.9 0.0 1.9 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 KIK63795.1 - 0.00049 20.6 0.5 0.038 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK63795.1 - 0.008 15.8 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK63795.1 - 0.0087 16.3 0.0 0.045 14.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 KIK63795.1 - 0.0089 16.5 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 KIK63795.1 - 0.012 15.3 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 KIK63795.1 - 0.013 15.6 0.2 0.047 13.7 0.2 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KIK63795.1 - 0.024 15.0 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 KIK63795.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ParA PF10609.9 KIK63795.1 - 0.045 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_33 PF13671.6 KIK63795.1 - 0.061 13.5 0.4 6.9 6.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain IPT PF01745.16 KIK63795.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.16 KIK63795.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Homeodomain PF00046.29 KIK63796.1 - 5.6e-05 22.9 0.1 0.0019 18.0 0.1 2.6 2 0 0 2 2 2 1 Homeodomain Tcp11 PF05794.13 KIK63796.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 T-complex protein 11 RcbX PF02341.15 KIK63796.1 - 0.091 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RbcX protein Homeodomain PF00046.29 KIK63797.1 - 0.00029 20.6 0.1 0.05 13.5 0.0 2.6 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 KIK63797.1 - 0.031 14.2 0.8 1.1 9.3 0.6 3.0 2 1 0 2 2 2 0 Homeobox KN domain potato_inhibit PF00280.18 KIK63797.1 - 0.23 12.1 0.9 0.59 10.9 0.1 2.1 2 0 0 2 2 2 0 Potato inhibitor I family Homeodomain PF00046.29 KIK63798.1 - 0.00046 20.0 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 Homeodomain AIM5 PF17050.5 KIK63798.1 - 0.51 11.2 0.0 0.51 11.2 0.0 2.8 3 1 0 3 3 3 0 Altered inheritance of mitochondria 5 Ribosomal_L27A PF00828.19 KIK63799.1 - 1.9e-34 119.1 0.0 6.7e-34 117.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PRP38 PF03371.15 KIK63800.1 - 1.8e-61 207.0 2.7 2.3e-61 206.7 2.7 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KIK63800.1 - 0.054 14.1 32.0 0.1 13.2 32.0 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HEAT_2 PF13646.6 KIK63800.1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 HEAT repeats PHD PF00628.29 KIK63801.1 - 1.9e-16 59.7 12.4 3.4e-10 39.7 0.7 2.7 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 KIK63801.1 - 0.002 17.7 10.0 0.11 12.1 0.5 2.8 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 KIK63801.1 - 0.0056 16.3 0.2 0.16 11.6 0.0 2.7 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain zf-Sec23_Sec24 PF04810.15 KIK63801.1 - 0.13 12.3 1.2 1.7 8.8 0.0 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-4CXXC_R1 PF10497.9 KIK63801.1 - 0.38 11.0 1.6 4.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 C1_1 PF00130.22 KIK63801.1 - 2.3 8.2 8.1 0.59 10.1 0.4 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KIK63801.1 - 2.4 8.3 8.8 12 6.1 0.8 2.5 2 0 0 2 2 2 0 PHD-finger DZR PF12773.7 KIK63801.1 - 6.5 6.9 7.3 1.6e+02 2.4 7.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 KIK63802.1 - 1.1e-54 185.6 0.0 1.5e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63802.1 - 5.7e-19 68.4 0.1 1e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK63802.1 - 0.0042 17.1 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK63802.1 - 0.016 14.8 0.5 0.03 13.9 0.5 1.4 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 KIK63802.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family BNIP2 PF12496.8 KIK63802.1 - 0.48 10.9 3.6 0.21 12.0 0.2 2.1 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Zn_clus PF00172.18 KIK63804.1 - 0.00056 20.0 16.5 0.00099 19.2 16.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCDHK_Adom3 PF10436.9 KIK63806.1 - 6.3e-37 126.9 0.0 9.1e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIK63806.1 - 3.2e-11 43.7 0.2 4.6e-08 33.6 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK63806.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase B12D PF06522.11 KIK63807.1 - 0.54 10.1 2.9 0.59 10.0 1.1 2.1 2 1 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cupin_2 PF07883.11 KIK63808.1 - 4.3e-10 39.2 0.1 0.00016 21.3 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KIK63808.1 - 0.021 14.5 0.4 0.32 10.6 0.1 2.4 2 0 0 2 2 2 0 Cupin EutQ PF06249.12 KIK63808.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KIK63808.1 - 0.033 13.9 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KIK63808.1 - 0.036 13.8 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Cupin Histone_H2A_C PF16211.5 KIK63808.1 - 0.2 11.4 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 C-terminus of histone H2A AAA PF00004.29 KIK63809.1 - 5.5e-41 140.1 0.0 1.3e-40 138.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK63809.1 - 1e-05 25.3 0.1 2.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KIK63809.1 - 5e-05 23.3 0.0 0.00019 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK63809.1 - 6.4e-05 23.2 0.1 0.0048 17.2 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 KIK63809.1 - 0.00025 21.2 0.0 0.00073 19.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIK63809.1 - 0.00078 19.9 0.4 0.014 15.8 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KIK63809.1 - 0.00082 18.6 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIK63809.1 - 0.0046 16.7 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIK63809.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KIK63809.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK63809.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIK63809.1 - 0.05 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIK63809.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KIK63809.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KIK63809.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KIK63809.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KIK63809.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KIK63809.1 - 0.1 12.5 0.5 35 4.2 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK63809.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KIK63809.1 - 0.12 12.1 0.1 0.66 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIK63809.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 KIK63810.1 - 1.3e-108 361.5 0.0 1.8e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KIK63810.1 - 9.7e-43 144.9 0.0 1.8e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KIK63810.1 - 5.2e-15 55.7 4.2 1.5e-14 54.2 4.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain zf-RING_4 PF14570.6 KIK63811.1 - 0.032 14.0 1.1 0.041 13.7 1.1 1.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RNA_pol_Rpc4 PF05132.14 KIK63813.1 - 8.9e-29 100.8 0.4 3.5e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase III RPC4 ABC_membrane PF00664.23 KIK63814.1 - 2.4e-49 168.4 24.7 2.8e-26 92.8 7.9 3.8 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KIK63814.1 - 4.3e-49 166.6 0.0 5.6e-29 101.4 0.0 2.7 2 1 0 2 2 2 2 ABC transporter T2SSE PF00437.20 KIK63814.1 - 3.5e-08 32.8 0.2 0.00012 21.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 KIK63814.1 - 1.7e-06 27.6 0.1 0.092 12.2 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK63814.1 - 0.00012 22.7 1.8 0.013 16.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KIK63814.1 - 0.00012 21.7 0.0 0.45 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK63814.1 - 0.00012 21.7 0.2 0.64 9.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK63814.1 - 0.00099 19.5 1.9 1.5 9.2 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK63814.1 - 0.002 18.0 3.1 0.92 9.3 0.1 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KIK63814.1 - 0.0051 16.7 0.3 1.1 9.2 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 KIK63814.1 - 0.01 16.0 0.5 0.05 13.7 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 KIK63814.1 - 0.013 15.5 1.3 3.4 7.6 0.0 4.2 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KIK63814.1 - 0.03 14.2 0.2 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KIK63814.1 - 0.088 12.3 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK63814.1 - 0.098 12.9 2.4 23 5.2 0.1 3.5 3 1 0 4 4 4 0 AAA domain AAA_33 PF13671.6 KIK63814.1 - 0.15 12.2 0.1 23 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIK63814.1 - 0.17 11.5 0.6 12 5.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain 7TM_GPCR_Srz PF10325.9 KIK63814.1 - 9.2 5.5 22.6 0.06 12.7 3.5 3.1 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srz NUDIX PF00293.28 KIK63815.1 - 9.2e-15 54.8 0.1 1.4e-13 51.0 0.0 2.3 1 1 2 3 3 3 2 NUDIX domain Mis14 PF08641.12 KIK63816.1 - 3e-08 34.0 0.9 4.7e-08 33.4 0.2 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like MbeD_MobD PF04899.12 KIK63816.1 - 0.17 12.0 1.3 7.1 6.8 0.0 2.8 2 1 1 3 3 3 0 MbeD/MobD like COX7C PF02935.16 KIK63817.1 - 4.3e-05 23.7 2.0 7.5e-05 22.9 2.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Na_H_Exchanger PF00999.21 KIK63818.1 - 1.4e-62 211.7 27.1 1.8e-62 211.3 27.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Apolipoprotein PF01442.18 KIK63818.1 - 0.013 15.4 2.5 0.02 14.8 2.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KIK63818.1 - 0.016 15.8 4.1 0.044 14.4 4.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.8 KIK63818.1 - 3.9 6.6 9.2 5.9 6.0 9.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein SDA1 PF05285.12 KIK63819.1 - 1.5e-88 297.6 31.1 1.5e-88 297.6 31.1 2.9 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 KIK63819.1 - 1.5e-20 73.2 0.0 6e-20 71.3 0.0 2.1 1 0 0 1 1 1 1 NUC130/3NT domain YL1 PF05764.13 KIK63819.1 - 0.033 14.3 0.3 0.033 14.3 0.3 4.3 3 1 0 3 3 3 0 YL1 nuclear protein LydB PF16084.5 KIK63820.1 - 0.03 14.1 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 LydA-holin antagonist EMG1 PF03587.14 KIK63821.1 - 4.1e-72 241.9 0.0 5.4e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_transf_8 PF01501.20 KIK63822.1 - 5.5e-06 26.1 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KIK63822.1 - 0.00078 18.9 0.1 0.0042 16.5 0.1 2.0 1 1 0 1 1 1 1 Glucosyltransferase 24 HRDC PF00570.23 KIK63823.1 - 0.0014 18.6 0.4 0.0083 16.1 0.4 2.1 1 1 0 1 1 1 1 HRDC domain SMC_N PF02463.19 KIK63824.1 - 1e-69 234.3 2.1 1.3e-69 234.0 2.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIK63824.1 - 1.1e-25 90.2 0.0 4e-25 88.4 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIK63824.1 - 7e-16 58.9 9.0 6.9e-08 32.6 5.7 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK63824.1 - 1.5e-12 47.9 18.0 7.4e-10 39.1 6.6 4.2 2 2 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 KIK63824.1 - 1.8e-09 38.4 36.9 1.8e-09 38.4 36.9 6.4 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KIK63824.1 - 0.0044 16.4 0.1 0.12 11.8 0.0 3.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 KIK63824.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Endonuc_BglI PF14562.6 KIK63824.1 - 0.088 11.9 0.3 0.19 10.8 0.3 1.5 1 0 0 1 1 1 0 Restriction endonuclease BglI ABC_tran PF00005.27 KIK63824.1 - 0.6 10.6 0.0 0.6 10.6 0.0 5.4 4 3 0 4 4 4 0 ABC transporter DUF87 PF01935.17 KIK63824.1 - 1.8 8.6 0.0 1.8 8.6 0.0 6.1 3 2 0 5 5 5 0 Helicase HerA, central domain DEAD PF00270.29 KIK63825.1 - 5.8e-45 153.2 0.0 1.6e-44 151.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63825.1 - 1.3e-26 93.1 0.4 5.6e-26 91.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63825.1 - 2.1e-07 31.1 0.1 2.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIK63825.1 - 0.00058 19.3 9.1 1.5 8.1 0.0 2.5 3 0 0 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit SAM_DrpA PF18255.1 KIK63825.1 - 0.15 12.3 0.0 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain VSG_B PF13206.6 KIK63825.1 - 2.1 7.5 9.0 3.1 6.9 9.0 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain PTPRCAP PF15713.5 KIK63825.1 - 4.8 7.5 15.6 9.4 6.5 15.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DDRGK PF09756.9 KIK63825.1 - 6.2 6.4 23.0 18 4.9 23.0 1.7 1 0 0 1 1 1 0 DDRGK domain GalP_UDP_transf PF01087.22 KIK63826.1 - 1.4e-58 198.3 0.0 2.1e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KIK63826.1 - 9.8e-48 162.0 0.0 1.8e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KIK63826.1 - 0.0062 17.3 0.2 0.038 14.7 0.2 2.3 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KIK63826.1 - 0.012 16.0 2.2 0.017 15.6 0.7 2.0 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding PNK3P PF08645.11 KIK63827.1 - 2.4e-42 144.4 0.0 4.4e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KIK63827.1 - 4.3e-18 65.8 0.0 3.1e-15 56.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain HAD_2 PF13419.6 KIK63827.1 - 0.0029 17.7 0.0 0.21 11.7 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 KIK63827.1 - 0.0043 17.4 0.0 0.009 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NIF PF03031.18 KIK63827.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase MMR_HSR1 PF01926.23 KIK63827.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hydrolase_6 PF13344.6 KIK63827.1 - 0.097 12.8 0.1 0.5 10.5 0.1 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 KIK63827.1 - 0.16 11.2 0.0 15 4.8 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin AAA PF00004.29 KIK63827.1 - 0.21 12.0 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HA2 PF04408.23 KIK63828.1 - 1.3e-17 64.1 0.0 2.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK63828.1 - 3.8e-14 53.0 0.0 8.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIK63828.1 - 8.3e-06 26.1 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DAGK_cat PF00781.24 KIK63829.1 - 2.2e-13 49.9 0.0 3.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NFRKB_winged PF14465.6 KIK63829.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 NFRKB Winged Helix-like ADK PF00406.22 KIK63830.1 - 8e-42 142.9 0.1 1.5e-41 142.0 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIK63830.1 - 3.1e-28 98.9 0.1 4.7e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK63830.1 - 7.7e-05 23.2 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KIK63830.1 - 0.0014 18.4 0.2 0.042 13.5 0.1 2.1 2 0 0 2 2 2 1 Thymidylate kinase PAS_7 PF12860.7 KIK63830.1 - 0.045 13.9 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 PAS fold WD40 PF00400.32 KIK63831.1 - 0.033 15.0 0.2 0.033 15.0 0.2 4.9 6 1 0 6 6 6 0 WD domain, G-beta repeat Fungal_trans PF04082.18 KIK63832.1 - 1.1e-08 34.4 0.0 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK63832.1 - 3.6e-05 23.8 12.5 6.3e-05 23.0 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_Cef PF11831.8 KIK63833.1 - 1.6e-64 217.8 1.3 1.6e-64 217.8 1.3 3.3 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KIK63833.1 - 2.5e-21 75.6 5.5 9.4e-11 41.7 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK63833.1 - 3.3e-18 65.7 5.4 3.2e-12 46.5 2.9 3.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Cep57_CLD PF14073.6 KIK63833.1 - 0.0098 15.9 13.1 0.0098 15.9 13.1 3.3 4 0 0 4 4 4 1 Centrosome localisation domain of Cep57 APG6_N PF17675.1 KIK63833.1 - 0.014 15.9 11.8 0.014 15.9 11.8 4.8 4 1 1 5 5 5 0 Apg6 coiled-coil region FliD_C PF07195.12 KIK63833.1 - 0.073 12.5 6.4 0.43 9.9 0.6 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin_2 PF01920.20 KIK63833.1 - 2.7 8.0 13.2 3.1 7.8 7.0 3.1 2 0 0 2 2 2 0 Prefoldin subunit Rap1_C PF11626.8 KIK63833.1 - 5.8 7.1 6.0 2.6 8.2 0.1 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1690 PF07956.11 KIK63835.1 - 2.8e-34 118.5 3.9 3.3e-34 118.3 3.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 KIK63835.1 - 0.003 17.6 4.5 0.004 17.2 4.5 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion FCH PF00611.23 KIK63835.1 - 0.067 13.5 1.6 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 KIK63835.1 - 0.073 12.4 4.4 0.087 12.2 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DRY_EERY PF09750.9 KIK63835.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.1 1 1 1 2 2 2 0 Alternative splicing regulator PCRF PF03462.18 KIK63835.1 - 2.1 8.2 8.3 1.9 8.3 3.3 2.0 1 1 1 2 2 2 0 PCRF domain zf-C2H2_4 PF13894.6 KIK63836.1 - 0.14 13.1 1.3 0.32 11.9 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Tudor_1_RapA PF18339.1 KIK63837.1 - 0.0051 16.7 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain 1 YEATS PF03366.16 KIK63837.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 YEATS family Peptidase_M16 PF00675.20 KIK63838.1 - 1.1e-53 181.2 0.5 3.5e-53 179.6 0.3 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK63838.1 - 4.5e-42 144.1 0.0 4.4e-39 134.4 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Sel1 PF08238.12 KIK63839.1 - 1.5e-49 165.3 28.1 6.3e-10 39.4 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.6 KIK63839.1 - 0.29 12.1 12.8 2.7 9.0 0.7 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK63839.1 - 2.5 8.9 6.8 32 5.5 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat JHD PF17811.1 KIK63840.1 - 1.4e-12 48.0 0.0 3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KIK63840.1 - 3.7e-06 27.3 2.5 3.7e-06 27.3 2.5 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 KIK63840.1 - 9.9e-05 22.2 9.1 0.00027 20.8 9.2 1.8 1 1 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 KIK63840.1 - 0.0018 18.1 1.1 0.014 15.1 1.1 2.2 1 1 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.6 KIK63840.1 - 0.69 9.5 5.9 1.4 8.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger PGK PF00162.19 KIK63841.1 - 2e-144 481.2 0.3 2.3e-144 481.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF4061 PF13270.6 KIK63842.1 - 0.076 13.3 5.8 0.19 12.0 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) Acyl_transf_1 PF00698.21 KIK63842.1 - 0.097 12.2 0.5 0.12 11.9 0.5 1.1 1 0 0 1 1 1 0 Acyl transferase domain YjbH PF06082.11 KIK63842.1 - 0.25 10.1 4.9 0.3 9.9 4.9 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Atg14 PF10186.9 KIK63842.1 - 0.68 9.0 5.2 0.8 8.7 5.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CN_hydrolase PF00795.22 KIK63843.1 - 6.4e-57 192.9 0.0 7.2e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF5121 PF17165.4 KIK63843.1 - 0.12 12.8 0.0 0.55 10.7 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5121) DnaJ_C PF01556.18 KIK63844.1 - 1.3e-41 142.1 1.0 1.7e-41 141.8 1.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK63844.1 - 1.4e-21 76.4 0.4 2.3e-21 75.7 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK63844.1 - 8.5e-15 54.9 22.2 1.5e-14 54.1 22.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIK63844.1 - 0.025 14.5 3.2 0.025 14.5 3.2 2.4 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KIK63844.1 - 0.046 13.8 5.5 0.19 11.8 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 KIK63844.1 - 0.95 9.5 10.9 2.6 8.1 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2340 PF10209.9 KIK63845.1 - 1.8e-53 180.1 0.7 2.1e-53 179.8 0.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KIK63845.1 - 0.0016 18.8 0.1 0.0019 18.5 0.1 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain UAE_UbL PF14732.6 KIK63845.1 - 0.081 13.5 0.1 0.19 12.4 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Glyco_hydro_3_C PF01915.22 KIK63846.1 - 1.2e-56 191.9 0.0 2.2e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK63846.1 - 1.9e-42 145.8 0.0 3.4e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK63846.1 - 2e-21 75.8 0.1 4.3e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIK63846.1 - 9.3e-17 61.2 0.0 1.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.9 KIK63846.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein GLEYA PF10528.9 KIK63846.1 - 0.018 15.5 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 GLEYA domain ProRS-C_1 PF09180.11 KIK63847.1 - 6.2e-26 90.4 0.3 1.3e-25 89.4 0.3 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KIK63847.1 - 2.8e-17 62.6 0.0 8e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIK63847.1 - 3.4e-16 59.7 0.0 5.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 KIK63847.1 - 4e-15 56.0 0.1 8.2e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF4459 PF14673.6 KIK63847.1 - 0.17 11.8 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Hydantoinase_B PF02538.14 KIK63848.1 - 1.3e-136 456.0 0.0 1.8e-136 455.6 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KIK63848.1 - 2.3e-87 293.0 3.3 2.6e-86 289.5 1.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIK63848.1 - 3.2e-44 150.7 0.1 4.7e-41 140.5 0.0 3.3 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KIK63848.1 - 1.2e-05 24.1 2.8 0.069 11.7 0.1 3.1 3 0 0 3 3 3 2 MutL protein PhyH PF05721.13 KIK63849.1 - 2.1e-21 77.2 0.0 3.3e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KIK63850.1 - 1.9e-91 307.2 30.1 2.2e-91 307.0 30.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK63850.1 - 2.6e-15 56.2 31.2 2.6e-15 56.2 31.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily RhoGEF PF00621.20 KIK63851.1 - 1.5e-26 93.7 0.0 2.5e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KIK63851.1 - 8.3e-18 64.3 10.8 1.5e-17 63.5 10.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KIK63851.1 - 0.00015 22.3 0.8 0.0031 18.0 0.0 3.2 3 0 0 3 3 3 1 PH domain FYVE_2 PF02318.16 KIK63851.1 - 9.1 6.5 7.8 22 5.3 7.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Nop53 PF07767.11 KIK63852.1 - 3.6e-82 276.9 4.1 4.2e-82 276.7 4.1 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TFIIB PF00382.19 KIK63853.1 - 4.8e-39 132.2 0.0 4.6e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KIK63853.1 - 1.2e-12 47.1 1.8 1.9e-12 46.5 1.8 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.16 KIK63853.1 - 0.0026 17.3 0.0 0.0093 15.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Guanylin PF02058.15 KIK63853.1 - 0.0057 17.1 2.1 7.2 7.2 0.1 3.2 1 1 1 3 3 3 3 Guanylin precursor Cyclin_N PF00134.23 KIK63853.1 - 0.016 14.9 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK63853.1 - 0.059 13.5 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain RB_B PF01857.20 KIK63853.1 - 0.067 13.2 0.1 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain TMIE PF16038.5 KIK63853.1 - 0.11 12.3 0.3 3.1 7.7 0.2 2.5 2 0 0 2 2 2 0 TMIE protein FH2 PF02181.23 KIK63854.1 - 1.7e-75 254.5 6.7 1.7e-75 254.5 6.7 2.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KIK63854.1 - 2.4e-35 121.8 1.8 4.2e-35 121.0 0.1 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KIK63854.1 - 2.9e-33 115.1 1.6 2.9e-33 115.1 1.6 3.2 3 1 1 4 4 4 1 Diaphanous FH3 Domain Pneumo_M2 PF07380.11 KIK63854.1 - 0.079 13.2 0.3 0.27 11.6 0.2 1.9 2 0 0 2 2 2 0 Pneumovirus M2 protein PAP2 PF01569.21 KIK63855.1 - 5.7e-25 87.7 3.2 5.7e-25 87.7 3.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily TMEM135_C_rich PF15982.5 KIK63855.1 - 0.11 13.1 0.2 0.22 12.1 0.2 1.4 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF2085 PF09858.9 KIK63855.1 - 2.7 8.5 5.3 1.5 9.3 1.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) KCH PF16944.5 KIK63856.1 - 0.0014 18.4 2.2 0.0021 17.9 2.2 1.2 1 0 0 1 1 1 1 Fungal potassium channel Nop14 PF04147.12 KIK63856.1 - 0.007 14.7 8.9 0.012 13.8 8.9 1.3 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KIK63856.1 - 0.47 8.7 7.4 0.88 7.8 7.4 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KIK63856.1 - 0.98 8.3 4.7 2.2 7.2 4.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 KIK63856.1 - 1.2 8.5 12.5 0.085 12.3 6.9 1.7 2 0 0 2 2 2 0 SDA1 NOA36 PF06524.12 KIK63856.1 - 1.4 8.1 13.1 0.0082 15.5 4.5 1.5 2 0 0 2 2 2 0 NOA36 protein CPSF100_C PF13299.6 KIK63856.1 - 1.8 8.7 4.2 4.7 7.4 4.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 KIK63856.1 - 2 8.5 14.2 0.017 15.3 5.2 2.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 KIK63856.1 - 2.4 6.8 7.0 4.2 6.0 7.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MCM_bind PF09739.9 KIK63856.1 - 2.9 6.2 3.7 4.3 5.6 3.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Paf1 PF03985.13 KIK63856.1 - 3.9 6.4 17.4 7.5 5.4 17.4 1.4 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 KIK63856.1 - 4.9 6.9 16.5 2 8.2 11.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Myc_N PF01056.18 KIK63856.1 - 8 6.2 20.2 0.013 15.4 6.7 2.6 2 1 1 3 3 3 0 Myc amino-terminal region Radial_spoke PF04712.12 KIK63856.1 - 9.4 5.0 15.5 17 4.2 15.5 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Sacchrp_dh_C PF16653.5 KIK63858.1 - 1.7e-84 284.0 0.0 1.6e-83 280.9 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KIK63858.1 - 4.6e-63 212.1 0.0 9.2e-63 211.1 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KIK63858.1 - 2.8e-24 84.8 1.4 3.9e-24 84.3 0.1 1.9 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 KIK63858.1 - 9e-23 81.0 0.6 1.6e-22 80.1 0.6 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIK63858.1 - 1.1e-08 35.3 1.4 2.8e-07 30.7 0.6 2.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 KIK63858.1 - 0.00031 21.4 0.0 0.011 16.5 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63858.1 - 0.00041 21.1 0.2 0.85 10.4 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain NAD_binding_10 PF13460.6 KIK63858.1 - 0.00047 20.1 0.2 0.00083 19.3 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 KIK63858.1 - 0.03 13.9 0.3 0.088 12.4 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_3 PF03447.16 KIK63858.1 - 0.067 13.8 0.4 0.13 12.9 0.4 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Myosin_head PF00063.21 KIK63859.1 - 2.2e-258 859.0 0.2 1.2e-257 856.5 0.0 2.2 2 1 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KIK63859.1 - 4.4e-26 91.2 1.8 4.4e-26 91.2 1.8 3.6 3 1 0 3 3 3 1 DIL domain IQ PF00612.27 KIK63859.1 - 3e-11 42.1 39.9 0.013 15.3 0.1 7.2 7 0 0 7 7 7 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KIK63859.1 - 0.035 14.0 0.2 0.075 12.9 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KIK63859.1 - 0.061 13.6 1.6 0.2 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 KIK63859.1 - 0.13 11.3 26.0 1.3 8.1 24.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_16 PF13191.6 KIK63859.1 - 0.56 10.6 0.0 0.56 10.6 0.0 3.5 2 1 0 2 2 2 0 AAA ATPase domain HMMR_C PF15908.5 KIK63859.1 - 2.7 8.3 17.8 11 6.2 14.8 2.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal ERM PF00769.19 KIK63859.1 - 4.6 7.0 26.7 10 5.8 26.7 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.15 KIK63859.1 - 9.8 6.0 12.9 0.72 9.7 5.5 3.0 1 1 0 2 2 2 0 Septum formation initiator Pectinesterase PF01095.19 KIK63860.1 - 3.7e-32 111.2 6.2 4.8e-32 110.9 6.2 1.1 1 0 0 1 1 1 1 Pectinesterase NGP1NT PF08153.12 KIK63861.1 - 1.9e-51 173.6 0.0 4.4e-51 172.4 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KIK63861.1 - 3.3e-17 62.6 0.1 1e-13 51.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK63861.1 - 1.7e-05 24.8 0.0 4.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KIK63861.1 - 2.2e-05 24.0 0.2 0.0003 20.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KIK63861.1 - 0.00083 18.9 0.0 0.069 12.7 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KIK63861.1 - 0.016 14.7 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KIK63861.1 - 0.13 12.5 0.1 7.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NOG1 PF06858.14 KIK63861.1 - 0.15 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Dynamin_N PF00350.23 KIK63861.1 - 0.32 11.0 4.1 19 5.3 0.1 3.8 3 1 1 4 4 4 0 Dynamin family Raptor_N PF14538.6 KIK63862.1 - 2.5e-64 215.7 0.0 5.9e-64 214.5 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KIK63862.1 - 1.8e-06 28.6 5.6 0.052 14.4 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 KIK63862.1 - 6.1e-05 22.9 0.4 0.001 19.1 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 KIK63862.1 - 0.00039 20.8 0.0 0.003 17.9 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KIK63862.1 - 0.00042 20.7 0.2 0.0049 17.3 0.0 2.9 3 0 0 3 3 3 1 HEAT-like repeat Peptidase_C14 PF00656.22 KIK63862.1 - 0.0087 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Semialdhyde_dhC PF02774.18 KIK63863.1 - 5.8e-39 134.1 0.1 3.2e-38 131.6 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KIK63863.1 - 4e-27 95.0 0.0 2.2e-26 92.7 0.0 2.0 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KIK63863.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KIK63863.1 - 0.099 13.4 0.1 0.33 11.7 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PBP PF01161.20 KIK63864.1 - 1.8e-10 41.2 0.0 2.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G-patch PF01585.23 KIK63865.1 - 2.2e-13 49.9 1.8 4.3e-13 48.9 1.8 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KIK63865.1 - 1.1e-12 47.6 0.1 2.9e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KIK63865.1 - 8.4e-05 22.6 2.4 8.4e-05 22.6 2.4 2.1 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 KIK63865.1 - 0.0039 17.4 0.8 0.007 16.6 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RED_N PF07808.13 KIK63865.1 - 0.035 13.7 1.1 0.078 12.5 1.1 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 KIK63865.1 - 0.06 13.7 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KIK63865.1 - 0.077 13.9 0.3 0.18 12.7 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger PHM7_cyt PF14703.6 KIK63865.1 - 0.1 12.8 0.1 5.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter zf-C2H2_11 PF16622.5 KIK63865.1 - 0.16 11.7 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type COQ7 PF03232.13 KIK63867.1 - 8.6e-67 224.2 0.7 9e-67 224.1 0.1 1.3 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 Lactamase_B_2 PF12706.7 KIK63869.1 - 1e-09 38.2 0.0 9.7e-08 31.8 0.0 2.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK63869.1 - 8.8e-06 25.9 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KIK63869.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II MFS_1 PF07690.16 KIK63870.1 - 6.4e-39 133.9 35.1 6.4e-39 133.9 35.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK63870.1 - 9e-07 28.1 4.2 9e-07 28.1 4.2 3.6 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK63870.1 - 0.00067 19.0 3.3 0.00067 19.0 3.3 2.7 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 KIK63871.1 - 3.1e-63 213.6 0.0 3.7e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63871.1 - 1.9e-24 86.3 0.0 3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK63871.1 - 7.7e-05 22.1 0.0 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIK63871.1 - 0.0034 17.3 0.1 0.04 13.8 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK63871.1 - 0.0094 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 KIK63871.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK63871.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KIK63872.1 - 2.3e-44 148.5 31.1 3.2e-07 30.9 0.2 9.3 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIK63872.1 - 1e-11 44.5 0.1 2.2e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK63872.1 - 7.1e-11 41.7 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KIK63872.1 - 2.2e-06 26.6 16.4 0.49 9.0 0.0 6.1 3 2 3 6 6 6 6 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK63872.1 - 3.1e-06 27.4 0.5 2.1 8.7 0.0 5.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KIK63872.1 - 0.0001 22.1 0.1 0.00065 19.6 0.0 2.4 3 0 0 3 3 3 1 F-box BBS2_Mid PF14783.6 KIK63872.1 - 0.0042 17.1 0.4 56 3.8 0.0 5.2 4 2 2 6 6 6 0 Ciliary BBSome complex subunit 2, middle region DLIC PF05783.11 KIK63873.1 - 2.3e-38 132.2 7.8 6.2e-27 94.6 0.0 5.5 5 1 0 5 5 5 4 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KIK63873.1 - 0.0025 18.3 0.1 0.0052 17.3 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK63873.1 - 0.0027 18.1 0.0 0.0073 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KIK63873.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KIK63873.1 - 0.014 15.1 0.2 0.041 13.6 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK63873.1 - 0.034 14.2 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KIK63873.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KIK63873.1 - 0.09 12.3 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KIK63873.1 - 0.1 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIK63873.1 - 0.18 11.7 0.3 11 5.8 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase Glyco_hydro_63 PF03200.16 KIK63875.1 - 1.8e-165 551.4 0.1 1.9e-164 548.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KIK63875.1 - 1.6e-80 270.5 0.0 3.3e-79 266.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KIK63875.1 - 0.00015 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Trehalase Band_7 PF01145.25 KIK63876.1 - 3e-05 24.1 0.0 3e-05 24.1 0.0 3.4 3 0 0 3 3 3 2 SPFH domain / Band 7 family Atg8 PF02991.16 KIK63877.1 - 6.1e-52 174.2 0.2 7.3e-52 173.9 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KIK63877.1 - 3.9e-07 30.4 0.0 4.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 TrmE_N PF10396.9 KIK63877.1 - 0.18 12.2 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Rad51 PF08423.11 KIK63879.1 - 3.4e-29 101.9 0.0 7.6e-29 100.7 0.0 1.3 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 KIK63879.1 - 1.7e-06 27.6 0.2 7.3e-06 25.5 0.2 1.9 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 KIK63879.1 - 0.0037 16.8 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KIK63879.1 - 0.12 11.7 1.1 0.85 8.9 0.1 2.2 2 0 0 2 2 2 0 KaiC DNA_pol_D_N PF18018.1 KIK63880.1 - 3.4e-43 146.9 0.0 5.9e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KIK63880.1 - 9.1e-28 97.0 0.5 1.4e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Peptidase_C50 PF03568.17 KIK63881.1 - 9.8e-139 462.8 0.0 1.7e-138 462.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 KIK63881.1 - 6.5e-07 29.6 15.6 0.012 15.9 0.0 7.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK63881.1 - 0.0008 18.9 8.5 0.034 13.5 0.2 4.3 3 1 1 4 4 4 1 MalT-like TPR region CHAT PF12770.7 KIK63881.1 - 0.00088 18.8 0.2 0.059 12.8 0.0 3.0 2 1 0 2 2 2 1 CHAT domain TPR_2 PF07719.17 KIK63881.1 - 0.038 14.1 8.5 21 5.6 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK63881.1 - 0.038 14.5 2.6 1.7 9.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK63881.1 - 0.048 13.9 6.6 5.7 7.2 0.1 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PhoD PF09423.10 KIK63882.1 - 7.1e-37 127.2 0.1 2.1e-36 125.7 0.1 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KIK63882.1 - 0.028 15.0 0.0 0.091 13.3 0.0 1.9 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KIK63882.1 - 0.14 12.3 0.0 0.92 9.7 0.1 2.2 2 0 0 2 2 2 0 Fibronectin type III domain Snf7 PF03357.21 KIK63883.1 - 1.8e-40 138.4 19.6 1.8e-40 138.4 19.6 1.7 2 0 0 2 2 2 1 Snf7 DUF1002 PF06207.11 KIK63883.1 - 0.26 10.8 3.7 0.11 12.1 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) YlqD PF11068.8 KIK63883.1 - 3.7 7.9 13.5 30 5.0 2.7 2.2 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 KIK63883.1 - 8.5 5.8 9.9 11 5.4 9.9 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Adap_comp_sub PF00928.21 KIK63884.1 - 2.2e-78 263.3 0.0 2.9e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK63884.1 - 1.4e-07 31.5 2.2 2.2e-07 30.9 2.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5618 PF18498.1 KIK63884.1 - 0.17 12.1 0.2 0.41 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) Dynactin PF12455.8 KIK63885.1 - 7.8e-71 238.6 3.6 2.6e-53 181.1 0.0 4.8 5 1 0 5 5 5 2 Dynein associated protein CAP_GLY PF01302.25 KIK63885.1 - 1e-21 76.7 2.3 2.1e-21 75.7 2.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain F_actin_bind PF08919.10 KIK63885.1 - 0.0065 16.5 0.6 0.092 12.8 0.7 3.0 2 0 0 2 2 2 1 F-actin binding DUF4219 PF13961.6 KIK63886.1 - 0.049 13.3 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Reprolysin_2 PF13574.6 KIK63886.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like COX5A PF02284.16 KIK63887.1 - 4.6e-43 145.4 0.2 6.4e-43 145.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va vATP-synt_E PF01991.18 KIK63888.1 - 1.1e-56 191.4 5.3 1.2e-56 191.3 5.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Pribosyltran PF00156.27 KIK63889.1 - 1.6e-17 63.5 0.3 2.3e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CDH-cyt PF16010.5 KIK63890.1 - 2e-50 171.0 0.8 3.6e-50 170.2 0.8 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KIK63890.1 - 1.3e-17 64.1 0.0 2.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK63890.1 - 9.6e-14 52.1 0.0 1.9e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK63890.1 - 0.054 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain rRNA_proc-arch PF13234.6 KIK63891.1 - 4.3e-88 295.8 0.1 7.3e-88 295.0 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KIK63891.1 - 2.2e-51 173.8 0.4 4.7e-51 172.7 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KIK63891.1 - 6.4e-17 61.9 0.1 3.2e-16 59.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63891.1 - 1.1e-07 32.1 0.1 1.3e-06 28.7 0.1 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63891.1 - 0.00057 19.9 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KIK63891.1 - 0.024 13.7 0.0 0.065 12.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Abhydrolase_3 PF07859.13 KIK63892.1 - 4.1e-19 69.3 0.0 1.4e-17 64.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK63892.1 - 8.4e-09 35.2 0.0 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIK63892.1 - 1.9e-05 24.6 0.0 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK63892.1 - 0.0041 16.0 0.0 0.0097 14.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 KIK63892.1 - 0.046 13.2 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KIK63892.1 - 0.096 11.9 0.0 0.26 10.5 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 KIK63892.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family DSHCT PF08148.12 KIK63893.1 - 1.4e-46 158.1 0.1 2e-46 157.7 0.1 1.2 1 0 0 1 1 1 1 DSHCT (NUC185) domain Abhydrolase_3 PF07859.13 KIK63894.1 - 6.5e-21 75.2 0.0 7.9e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK63894.1 - 3.3e-09 36.5 0.0 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIK63894.1 - 1.6e-06 28.1 0.0 0.00087 19.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK63894.1 - 9.8e-05 21.4 0.0 0.00022 20.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KIK63894.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KIK63894.1 - 0.063 12.8 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DLH PF01738.18 KIK63894.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Ras PF00071.22 KIK63895.1 - 7.7e-34 116.6 0.3 9.5e-34 116.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK63895.1 - 1.3e-25 89.9 0.3 3.3e-25 88.6 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK63895.1 - 8.7e-08 31.8 0.1 1.1e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK63895.1 - 4.9e-07 29.3 0.2 6.4e-07 29.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KIK63895.1 - 0.0086 15.5 0.0 1.7 8.0 0.0 2.3 2 1 0 2 2 2 2 Bacterial TniB protein DLIC PF05783.11 KIK63895.1 - 0.012 14.5 0.6 1.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KIK63895.1 - 0.019 14.1 2.3 0.11 11.6 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KIK63895.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Catalase PF00199.19 KIK63896.1 - 3.5e-184 612.3 0.1 4.3e-184 612.0 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK63896.1 - 2.8e-14 53.1 0.2 7.3e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive EABR PF12180.8 KIK63896.1 - 0.014 15.0 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Sterol_MT_C PF08498.10 KIK63897.1 - 1.2e-26 92.7 1.7 2.3e-26 91.9 1.7 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KIK63897.1 - 2.3e-18 66.4 0.0 4e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK63897.1 - 3.4e-16 59.7 0.1 6.4e-16 58.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK63897.1 - 2.6e-15 56.9 0.1 6.8e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK63897.1 - 1.5e-11 44.4 0.0 2.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63897.1 - 8.5e-10 39.3 0.0 1.3e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK63897.1 - 1.1e-08 34.7 0.1 1.4e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KIK63897.1 - 1.6e-08 34.1 0.0 3e-08 33.3 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK63897.1 - 9.3e-06 25.5 0.2 1.3e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KIK63897.1 - 0.001 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 KIK63897.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KIK63897.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 KIK63897.1 - 0.0021 17.8 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 KIK63897.1 - 0.0029 18.6 0.0 0.0087 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 KIK63897.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 KIK63897.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Tfb5 PF06331.12 KIK63898.1 - 6.9e-24 83.6 0.7 7.4e-24 83.5 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Rib_5-P_isom_A PF06026.14 KIK63899.1 - 2.4e-57 193.3 0.0 3e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) EPSP_synthase PF00275.20 KIK63900.1 - 6.7e-126 420.3 0.1 1.2e-125 419.6 0.1 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KIK63900.1 - 2.6e-98 328.4 0.0 6e-98 327.2 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KIK63900.1 - 8.9e-53 179.9 0.0 1.8e-52 178.9 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KIK63900.1 - 1.4e-28 100.0 0.0 1e-27 97.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KIK63900.1 - 3.5e-25 88.1 0.0 9.9e-25 86.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KIK63900.1 - 7e-08 32.6 0.0 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KIK63900.1 - 6.7e-07 29.0 1.0 1.8e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KIK63900.1 - 7e-07 29.2 0.2 1.7e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AlaDh_PNT_C PF01262.21 KIK63900.1 - 0.056 12.7 0.9 0.38 10.0 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KIK63900.1 - 0.061 13.6 0.1 3.5 7.9 0.0 3.6 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain AAA_33 PF13671.6 KIK63900.1 - 0.094 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DegS PF05384.11 KIK63900.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Sensor protein DegS 6PF2K PF01591.18 KIK63900.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase IF4E PF01652.18 KIK63901.1 - 5.8e-49 165.9 0.1 1.1e-48 165.1 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 KIK63901.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) DUF218 PF02698.17 KIK63902.1 - 2.2e-24 85.9 0.0 2.8e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Ubiq_cyt_C_chap PF03981.12 KIK63903.1 - 1e-22 80.8 0.0 4.2e-13 49.6 0.0 2.9 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone DUF2573 PF10835.8 KIK63903.1 - 0.091 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Pyr_redox_2 PF07992.14 KIK63904.1 - 1.9e-49 168.5 0.0 2.7e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK63904.1 - 7.3e-09 36.1 1.2 1.5e-07 31.9 0.0 3.3 4 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK63904.1 - 0.014 14.7 0.0 0.91 8.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK63904.1 - 0.085 13.3 1.2 0.66 10.4 0.0 2.8 2 2 0 2 2 2 0 Putative NAD(P)-binding Ferric_reduct PF01794.19 KIK63905.1 - 4.9e-19 68.7 4.1 4.9e-19 68.7 4.1 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK63905.1 - 2.3e-13 50.2 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIK63905.1 - 6.7e-09 36.1 0.0 4e-07 30.3 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain PIG-U PF06728.13 KIK63906.1 - 1.8e-95 320.3 23.3 2e-95 320.1 23.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U SPT_ssu-like PF11779.8 KIK63907.1 - 1e-09 37.8 3.2 1.4e-09 37.4 3.2 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Glyco_transf_18 PF15024.6 KIK63908.1 - 8.7e-06 24.6 0.0 1.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 hSac2 PF12456.8 KIK63908.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Inositol phosphatase Nuf2 PF03800.14 KIK63909.1 - 3.6e-30 104.9 0.1 3.6e-30 104.9 0.1 1.9 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KIK63909.1 - 1.5e-26 92.7 23.3 1.5e-26 92.7 23.3 3.6 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain Filament PF00038.21 KIK63909.1 - 0.0064 16.1 45.8 0.007 16.0 7.1 3.1 1 1 2 3 3 3 2 Intermediate filament protein GAS PF13851.6 KIK63909.1 - 0.094 12.1 47.6 0.14 11.5 17.1 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KIK63909.1 - 0.12 11.7 33.1 0.72 9.2 23.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4047 PF13256.6 KIK63909.1 - 4.3 7.5 22.6 8.5 6.6 5.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) NPV_P10 PF05531.12 KIK63909.1 - 4.3 7.9 22.4 15 6.2 1.9 4.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KIK63909.1 - 6.8 7.2 57.8 8 7.0 7.8 3.7 3 2 1 4 4 4 0 Apg6 coiled-coil region ThiF PF00899.21 KIK63910.1 - 6.3e-13 48.6 0.6 6.6e-12 45.3 0.6 2.0 1 1 0 1 1 1 1 ThiF family Adap_comp_sub PF00928.21 KIK63911.1 - 3.1e-22 79.2 0.0 4.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK63911.1 - 1.9e-07 31.1 0.1 3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phytoreo_Pns PF05451.11 KIK63911.1 - 0.081 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 DUF1464 PF07318.12 KIK63911.1 - 0.13 11.4 0.2 0.19 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) DUF4337 PF14235.6 KIK63911.1 - 2.6 8.1 4.2 4.4 7.4 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RRM_1 PF00076.22 KIK63912.1 - 1.7e-10 40.5 0.1 3.6e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK63912.1 - 0.0072 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KIK63912.1 - 0.045 14.0 0.7 0.2 11.8 0.0 2.2 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM PF05172.13 KIK63912.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif An_peroxidase PF03098.15 KIK63913.1 - 3.4e-27 95.2 0.0 7.7e-22 77.5 0.0 3.3 1 1 1 2 2 2 2 Animal haem peroxidase ENTH PF01417.20 KIK63914.1 - 1.6e-51 173.5 0.1 3.4e-51 172.5 0.1 1.6 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KIK63914.1 - 0.065 13.2 15.6 0.5 10.4 4.1 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif FYVE_2 PF02318.16 KIK63915.1 - 0.074 13.3 13.0 0.44 10.8 1.5 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Siva PF05458.12 KIK63915.1 - 3.5 7.3 19.5 1.2 8.7 9.7 2.1 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Tnp_zf-ribbon_2 PF13842.6 KIK63915.1 - 9.3 7.2 23.1 2.5 9.0 7.6 2.8 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Myosin_tail_1 PF01576.19 KIK63916.1 - 2.3e-06 25.8 112.9 5e-06 24.7 105.6 2.9 1 1 1 2 2 2 2 Myosin tail TolA_bind_tri PF16331.5 KIK63916.1 - 0.00015 21.8 3.4 0.00015 21.8 3.4 9.3 6 3 1 7 7 7 1 TolA binding protein trimerisation Filament PF00038.21 KIK63916.1 - 0.012 15.2 101.5 0.91 9.0 12.5 6.1 1 1 5 6 6 6 0 Intermediate filament protein CLZ PF16526.5 KIK63916.1 - 0.021 15.1 1.3 0.021 15.1 1.3 9.0 6 4 2 9 9 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myosin_head PF00063.21 KIK63917.1 - 5.6e-254 844.4 0.0 9.3e-254 843.7 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KIK63917.1 - 4.2e-09 36.1 1.1 1e-08 34.8 1.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KIK63917.1 - 0.00097 17.1 67.9 0.0013 16.7 67.9 1.1 1 0 0 1 1 1 1 Myosin tail AAA_22 PF13401.6 KIK63917.1 - 0.019 15.2 0.0 0.019 15.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain Cob_adeno_trans PF01923.18 KIK63917.1 - 0.071 13.2 11.1 0.043 14.0 3.9 3.1 3 0 0 3 3 3 0 Cobalamin adenosyltransferase AAA_16 PF13191.6 KIK63917.1 - 0.23 11.8 0.0 0.23 11.8 0.0 3.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KIK63917.1 - 0.99 9.7 0.0 0.99 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain S4 PF01479.25 KIK63918.1 - 1.9e-11 43.5 0.0 3.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KIK63918.1 - 0.039 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 S4 domain E1_dh PF00676.20 KIK63919.1 - 7.7e-112 373.1 0.0 9e-112 372.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KIK63919.1 - 0.00057 19.2 0.0 0.0012 18.1 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.25 KIK63920.1 - 1.1e-72 244.6 0.0 1.5e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK63920.1 - 1.7e-34 119.3 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIK63920.1 - 5.4e-13 49.4 4.4 7.8e-13 48.9 2.9 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIK63920.1 - 1.4e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK63920.1 - 0.0022 17.4 0.0 0.0045 16.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK63920.1 - 0.069 12.8 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK63920.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK63920.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.19 KIK63921.1 - 2.9e-41 141.9 0.1 1.3e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KIK63921.1 - 6.2e-05 21.9 0.4 0.013 14.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KIK63921.1 - 0.00029 20.2 0.8 0.023 13.9 0.8 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK63921.1 - 0.0018 18.3 0.3 0.31 11.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK63921.1 - 0.067 12.4 1.2 0.46 9.7 1.4 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK63921.1 - 0.092 11.6 0.2 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 KIK63921.1 - 0.14 11.4 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 KIK63921.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family SE PF08491.10 KIK63921.1 - 0.17 10.9 0.1 0.36 9.8 0.1 1.4 1 1 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 KIK63921.1 - 0.21 11.2 3.3 1.4 8.4 0.8 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_59 PF02057.15 KIK63922.1 - 2.2e-18 66.5 0.1 2.9e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 CBM_1 PF00734.18 KIK63922.1 - 8.8e-13 48.0 1.3 8.8e-13 48.0 1.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_30C PF17189.4 KIK63922.1 - 5.4e-10 39.3 12.1 4.4e-09 36.4 12.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 KIK63922.1 - 1.6e-08 34.6 2.8 2.6e-08 33.9 0.0 2.1 1 1 1 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 KIK63922.1 - 4.5e-08 32.4 0.0 6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain EF-hand_6 PF13405.6 KIK63923.1 - 1.8e-12 46.1 0.3 0.00011 21.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIK63923.1 - 2.8e-12 46.9 0.0 1.8e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIK63923.1 - 1.8e-11 42.7 0.1 0.00032 20.0 0.0 3.4 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KIK63923.1 - 1.1e-06 28.9 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KIK63923.1 - 6.2e-05 22.8 0.1 0.0017 18.2 0.1 2.6 2 2 0 2 2 2 1 EF-hand domain pair SapB_1 PF05184.15 KIK63923.1 - 0.017 15.1 0.1 4.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_11 PF08976.11 KIK63923.1 - 0.03 15.2 0.0 0.047 14.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain ExbD PF02472.16 KIK63923.1 - 0.039 14.1 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR EF-hand_5 PF13202.6 KIK63923.1 - 0.069 12.7 1.8 0.66 9.6 0.2 2.6 2 1 0 2 2 2 0 EF hand DDE_Tnp_IS66_C PF13817.6 KIK63923.1 - 0.15 12.3 0.3 0.41 10.9 0.1 1.7 2 0 0 2 2 2 0 IS66 C-terminal element Peptidase_M50 PF02163.22 KIK63925.1 - 1.4e-13 50.7 4.8 1e-05 24.9 0.1 3.2 2 1 0 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 KIK63925.1 - 0.16 12.3 0.1 0.28 11.6 0.1 1.3 1 0 0 1 1 1 0 PDZ domain RSN1_7TM PF02714.15 KIK63926.1 - 9.1e-76 254.8 21.6 1.6e-75 253.9 21.6 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIK63926.1 - 1.1e-36 126.0 0.8 1.1e-36 126.0 0.8 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIK63926.1 - 1.3e-32 113.4 0.0 2e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 KIK63926.1 - 0.024 14.5 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM174 PF15029.6 KIK63926.1 - 0.042 13.6 1.2 0.085 12.6 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 174 Glyco_hydro_71 PF03659.14 KIK63927.1 - 1.8e-109 366.0 0.3 3.4e-109 365.1 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 CMAS PF02353.20 KIK63929.1 - 2.4e-64 217.3 0.1 2.9e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK63929.1 - 2.4e-11 44.2 0.0 2e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK63929.1 - 4.5e-11 43.2 0.0 6.3e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK63929.1 - 1.7e-10 41.0 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK63929.1 - 3.2e-07 31.0 0.0 1e-06 29.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 KIK63929.1 - 1.8e-05 24.4 0.0 4.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KIK63929.1 - 0.00055 19.8 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK63929.1 - 0.00096 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KIK63929.1 - 0.033 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KIK63929.1 - 0.063 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 KIK63929.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 KIK63929.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 KIK63929.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KIK63931.1 - 2e-76 257.6 0.0 2.6e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nrap_D4 PF17405.2 KIK63933.1 - 5.6e-57 192.5 0.2 2e-56 190.7 0.0 2.0 3 0 0 3 3 3 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KIK63933.1 - 9.9e-44 148.8 0.0 7.2e-43 146.0 0.0 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KIK63933.1 - 1.9e-42 145.1 0.0 3.2e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 KIK63933.1 - 2e-40 138.2 0.0 6.4e-37 126.8 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 KIK63933.1 - 8.4e-37 126.6 0.1 1.7e-36 125.5 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KIK63933.1 - 2.4e-28 99.0 0.0 6e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 6 TFIIA PF03153.13 KIK63934.1 - 5.6 6.8 32.7 6.9 6.5 32.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2856 PF11043.8 KIK63935.1 - 0.062 13.4 0.8 0.4 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) Tetraspanin PF00335.20 KIK63936.1 - 0.0065 16.2 6.4 0.0065 16.2 6.4 1.5 1 1 1 2 2 2 1 Tetraspanin family DUF981 PF06168.11 KIK63936.1 - 0.12 12.3 8.6 0.21 11.5 8.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF981) PSII PF00421.19 KIK63936.1 - 1.1 7.9 3.8 1.6 7.3 3.8 1.1 1 0 0 1 1 1 0 Photosystem II protein Ribosomal_L38e PF01781.18 KIK63937.1 - 2.6e-32 110.7 0.4 3e-32 110.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family E1-E2_ATPase PF00122.20 KIK63938.1 - 6.2e-20 71.5 0.0 3.7e-16 59.2 0.1 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KIK63938.1 - 1.3e-14 55.0 0.1 6.7e-08 33.1 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK63938.1 - 0.0015 18.2 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KIK63938.1 - 0.003 17.6 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK63938.1 - 0.037 13.8 0.5 0.094 12.4 0.0 1.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 KIK63939.1 - 3.5e-22 79.1 0.0 6e-22 78.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIK63939.1 - 2.4e-05 23.3 0.0 4.2e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Steroid_dh PF02544.16 KIK63940.1 - 1.7e-28 99.5 3.9 4.5e-17 62.4 0.5 2.9 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KIK63940.1 - 4.9e-05 23.0 0.5 9.4e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) zf-B_box PF00643.24 KIK63941.1 - 0.02 15.1 0.1 0.02 15.1 0.1 7.3 5 1 2 7 7 7 0 B-box zinc finger Pro-kuma_activ PF09286.11 KIK63943.1 - 5e-43 146.8 0.7 8.5e-43 146.1 0.7 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK63943.1 - 8.4e-06 25.2 0.9 1.4e-05 24.6 0.9 1.3 1 0 0 1 1 1 1 Subtilase family DNA_binding_1 PF01035.20 KIK63944.1 - 7.9e-12 45.1 0.0 9.9e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF1110 PF06533.12 KIK63946.1 - 0.12 12.3 6.3 0.12 12.4 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) GAS PF13851.6 KIK63946.1 - 0.28 10.5 22.1 0.17 11.2 18.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KIK63946.1 - 2.3 7.5 13.3 4.8 6.5 13.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KIK63946.1 - 3.6 6.6 14.0 9.9 5.1 14.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CHAT PF12770.7 KIK63947.1 - 2.2e-35 122.5 0.0 4.3e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK63947.1 - 5.4e-13 48.3 23.3 0.023 14.5 0.3 12.1 12 1 0 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK63947.1 - 1.4e-09 37.3 4.1 0.79 9.9 0.0 10.4 11 1 0 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK63947.1 - 1.2e-08 34.4 3.7 8.9 6.8 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK63947.1 - 3.2e-08 33.7 13.7 8.3 7.5 0.0 10.3 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK63947.1 - 1.2e-06 28.2 14.9 6.8 7.1 0.0 9.9 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK63947.1 - 2.1e-05 24.7 11.3 4.1 7.8 0.2 8.5 7 3 2 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK63947.1 - 0.00055 19.6 15.6 21 5.1 0.0 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK63947.1 - 0.001 18.7 7.9 23 4.8 0.0 7.5 8 0 0 8 8 8 0 TPR repeat CPL PF08144.11 KIK63949.1 - 1.6e-26 93.4 0.0 5.1e-24 85.2 0.0 3.8 3 1 0 3 3 3 1 CPL (NUC119) domain TT_ORF2 PF02957.15 KIK63949.1 - 0.33 11.9 5.5 0.38 11.7 3.1 2.3 2 0 0 2 2 2 0 TT viral ORF2 DUF3474 PF11960.8 KIK63949.1 - 1.1 9.5 4.1 0.67 10.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Ndc1_Nup PF09531.10 KIK63949.1 - 4.1 6.0 4.5 6.1 5.4 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TarH PF02203.15 KIK63950.1 - 0.085 12.8 0.3 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue STAC2_u1 PF16664.5 KIK63951.1 - 0.037 14.5 0.4 9.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 LysM PF01476.20 KIK63952.1 - 6.7e-15 54.9 1.0 8.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 LysM domain DUF4772 PF15997.5 KIK63952.1 - 0.0044 17.6 0.1 0.0068 17.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4772) UQ_con PF00179.26 KIK63953.1 - 4.3e-36 123.6 0.0 4.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIK63953.1 - 0.00021 21.2 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KIK63953.1 - 0.0078 15.9 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Complex1_LYR PF05347.15 KIK63953.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DEAD PF00270.29 KIK63954.1 - 1e-36 126.4 0.1 1.8e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK63954.1 - 8.8e-22 77.6 0.0 7.4e-19 68.1 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK63954.1 - 3.2e-08 33.8 0.0 6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK63954.1 - 0.00012 21.3 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Transpeptidase PF00905.22 KIK63954.1 - 0.0082 15.4 0.3 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain AAA_19 PF13245.6 KIK63954.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK63954.1 - 0.023 14.4 0.3 0.063 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain zf-CRD PF17979.1 KIK63954.1 - 0.24 11.5 0.0 0.47 10.5 0.0 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions EI24 PF07264.11 KIK63956.1 - 8.2e-13 49.0 2.4 1.3e-12 48.3 2.4 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) YL1_C PF08265.11 KIK63957.1 - 1.3e-15 56.8 0.4 1.9e-15 56.3 0.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CorA PF01544.18 KIK63958.1 - 5.2e-09 35.8 1.2 5.8e-08 32.4 0.4 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein UBN_AB PF14075.6 KIK63959.1 - 8.1e-47 159.7 0.2 8.1e-47 159.7 0.2 2.9 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KIK63959.1 - 3.1e-14 52.7 0.4 9.3e-14 51.2 0.4 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Aminoglyc_resit PF10706.9 KIK63960.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Aminoglycoside-2''-adenylyltransferase Chromo PF00385.24 KIK63961.1 - 1.5e-10 40.8 0.1 4.1e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ATP-synt_E PF05680.12 KIK63961.1 - 0.4 11.0 5.2 0.78 10.1 5.2 1.5 1 0 0 1 1 1 0 ATP synthase E chain DUF4770 PF15994.5 KIK63961.1 - 0.71 10.1 4.9 1.2 9.4 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4748 PF15932.5 KIK63961.1 - 7.9 6.3 6.5 21 5.0 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4748) Peptidase_M14 PF00246.24 KIK63962.1 - 1.1e-61 209.2 0.0 1.4e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase 3-HAO PF06052.12 KIK63963.1 - 2.7e-60 202.4 0.0 3e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KIK63963.1 - 5e-06 26.1 0.1 8.3e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIK63963.1 - 0.00043 20.2 0.2 0.0007 19.5 0.2 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIK63963.1 - 0.036 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Whi5 PF08528.11 KIK63964.1 - 1.1e-07 31.3 0.7 1.9e-07 30.5 0.7 1.4 1 0 0 1 1 1 1 Whi5 like Rad17 PF03215.15 KIK63965.1 - 3.1e-26 92.4 0.0 8.5e-26 91.0 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KIK63965.1 - 0.0076 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK63965.1 - 0.009 16.4 0.0 0.03 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KIK63965.1 - 0.029 14.7 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain AAA PF00004.29 KIK63965.1 - 0.049 14.1 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK63965.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK63965.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 KIK63965.1 - 0.23 10.3 0.1 0.59 9.0 0.0 1.6 2 0 0 2 2 2 0 PrkA AAA domain LVIVD PF08309.11 KIK63966.1 - 0.096 12.0 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 LVIVD repeat zf-MYND PF01753.18 KIK63967.1 - 5.7e-10 39.1 11.8 5.7e-10 39.1 11.8 2.4 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 KIK63967.1 - 0.15 12.2 4.0 0.38 10.9 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Phage_tail_APC PF16778.5 KIK63967.1 - 0.18 11.7 3.0 0.89 9.5 0.6 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein YL1 PF05764.13 KIK63967.1 - 0.66 10.0 3.8 1 9.4 3.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Mem_trans PF03547.18 KIK63968.1 - 5e-21 74.5 15.5 2.4e-20 72.3 15.5 1.8 1 1 0 1 1 1 1 Membrane transport protein DX PF01666.17 KIK63970.1 - 0.021 15.2 0.0 0.024 15.1 0.0 1.1 1 0 0 1 1 1 0 DX module DUF2706 PF10913.8 KIK63970.1 - 0.028 14.3 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Dickkopf_N PF04706.12 KIK63970.1 - 0.029 14.8 0.1 0.042 14.3 0.1 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Nodulin_late PF07127.11 KIK63970.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Late nodulin protein DUF4810 PF16068.5 KIK63971.1 - 0.066 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) PNP_UDP_1 PF01048.20 KIK63972.1 - 1.7e-27 96.2 0.0 2.4e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily PEP_mutase PF13714.6 KIK63973.1 - 9.8e-61 205.2 0.4 1.1e-60 205.1 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.24 KIK63973.1 - 0.03 13.8 0.0 0.068 12.6 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Radical_SAM PF04055.21 KIK63973.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 Radical SAM superfamily M-factor PF03855.13 KIK63974.1 - 0.011 15.9 0.3 0.031 14.4 0.1 1.8 2 0 0 2 2 2 0 M-factor Hydrolase_4 PF12146.8 KIK63975.1 - 2.5e-12 46.6 0.0 5.1e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK63975.1 - 6.6e-11 42.3 0.2 6.4e-09 35.8 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK63975.1 - 3.9e-05 24.4 0.0 5.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KIK63975.1 - 0.0008 19.3 0.0 2.6 7.8 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KIK63975.1 - 0.06 13.4 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 KIK63975.1 - 0.19 11.6 0.0 1.7 8.5 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3592 PF12158.8 KIK63977.1 - 4.8 7.2 5.5 2.5 8.1 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) zf-RING_2 PF13639.6 KIK63978.1 - 1.8e-13 50.6 5.2 2.7e-13 50.0 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK63978.1 - 3.9e-09 36.4 2.1 7.4e-09 35.5 2.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK63978.1 - 5e-08 32.6 5.2 8.1e-08 32.0 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK63978.1 - 1.4e-07 31.3 1.7 2.2e-07 30.6 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK63978.1 - 4.3e-07 29.7 3.8 6.7e-07 29.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK63978.1 - 2.9e-06 27.5 9.3 6.7e-06 26.3 8.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KIK63978.1 - 2.3e-05 24.2 1.9 3.7e-05 23.6 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KIK63978.1 - 7.4e-05 22.4 1.3 0.00015 21.4 0.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KIK63978.1 - 0.0023 17.9 3.9 0.012 15.7 4.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK63978.1 - 0.0042 16.7 2.7 0.0074 15.9 2.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KIK63978.1 - 0.0046 16.7 3.0 0.0096 15.7 3.0 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KIK63978.1 - 0.0063 16.3 7.7 0.29 11.0 7.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 KIK63978.1 - 0.0073 16.0 3.5 0.015 15.0 0.8 2.1 2 0 0 2 2 2 1 P-11 zinc finger RINGv PF12906.7 KIK63978.1 - 0.014 15.5 9.2 0.03 14.4 7.8 2.0 1 1 1 2 2 2 0 RING-variant domain PHD PF00628.29 KIK63978.1 - 0.027 14.3 4.0 0.052 13.4 4.0 1.5 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_5 PF17121.5 KIK63978.1 - 0.17 11.8 2.3 0.35 10.8 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIK63978.1 - 0.18 12.0 7.5 1.7 8.9 7.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 KIK63978.1 - 0.2 11.6 0.3 23 4.9 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 KIK63978.1 - 0.23 11.6 2.0 0.45 10.7 2.0 1.4 1 1 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_1 PF14446.6 KIK63978.1 - 1.2 9.2 4.1 5.2 7.1 2.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 KIK63978.1 - 1.4 9.3 6.6 0.92 9.9 2.7 2.2 2 0 0 2 2 2 0 RING-like domain HpcH_HpaI PF03328.14 KIK63982.1 - 2.6e-30 105.2 0.0 3.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KIK63982.1 - 0.00089 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Epimerase PF01370.21 KIK63983.1 - 1.2e-18 67.5 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK63983.1 - 1.3e-09 37.5 0.0 4.1e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK63983.1 - 4.7e-09 36.1 0.0 2.4e-08 33.7 0.0 2.2 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK63983.1 - 4.8e-09 35.8 0.1 2.9e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KIK63983.1 - 1.3e-06 28.4 0.1 2.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KIK63983.1 - 0.00013 21.5 0.1 0.00013 21.5 0.1 2.4 3 1 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KIK63983.1 - 0.00016 20.9 0.1 0.00021 20.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIK63983.1 - 0.0065 16.4 0.1 0.048 13.6 0.1 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KIK63983.1 - 0.046 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KIK63983.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Cons_hypoth95 PF03602.15 KIK63983.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Stealth_CR3 PF17102.5 KIK63984.1 - 0.12 12.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 HD PF01966.22 KIK63985.1 - 0.019 15.2 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 HD domain UPF0172 PF03665.13 KIK63986.1 - 4.3e-55 186.7 0.0 4.9e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 KIK63986.1 - 0.0025 17.8 0.0 0.0042 17.1 0.0 1.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Methyltransf_2 PF00891.18 KIK63987.1 - 1.1e-09 37.9 0.1 5.4e-05 22.6 0.0 3.2 3 0 0 3 3 3 3 O-methyltransferase domain SSF PF00474.17 KIK63988.1 - 1.1e-15 57.4 24.2 1.1e-15 57.4 24.2 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family APG12 PF04110.13 KIK63990.1 - 1.5e-29 102.2 0.1 1.9e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Aldedh PF00171.22 KIK63992.1 - 9e-183 608.0 0.1 1e-182 607.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK63992.1 - 0.00044 19.4 0.0 0.45 9.5 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) TctC PF03401.14 KIK63992.1 - 0.16 11.0 0.1 0.27 10.3 0.1 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Aldedh PF00171.22 KIK63993.1 - 2.2e-183 610.0 0.1 2.5e-183 609.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK63993.1 - 0.00056 19.1 0.0 0.031 13.3 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Podoplanin PF05808.11 KIK63994.1 - 0.33 11.0 2.2 0.37 10.9 1.2 1.5 2 0 0 2 2 2 0 Podoplanin Glyoxal_oxid_N PF07250.11 KIK63995.1 - 0.0013 18.0 0.1 0.0015 17.8 0.1 1.1 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus Bestrophin PF01062.21 KIK63996.1 - 2.7e-31 109.1 4.5 2.6e-21 76.3 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4131 PF13567.6 KIK63996.1 - 1.3 8.6 6.9 0.59 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) eIF_4G1 PF12152.8 KIK63997.1 - 0.44 10.8 3.0 11 6.3 0.3 2.6 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 DAP3 PF10236.9 KIK63998.1 - 8.2e-64 215.7 0.0 1.1e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KIK63998.1 - 2.4e-08 34.6 0.1 4.2e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK63998.1 - 1.6e-06 28.2 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KIK63998.1 - 0.017 14.7 0.2 0.058 13.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK63998.1 - 0.023 15.0 0.2 0.15 12.4 0.3 2.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK63998.1 - 0.028 14.7 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK63998.1 - 0.047 13.2 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_10 PF12846.7 KIK63998.1 - 0.062 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.17 KIK63998.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KIK63998.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain HGTP_anticodon PF03129.20 KIK64001.1 - 2.1e-23 82.3 0.0 5.7e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIK64001.1 - 6.6e-11 42.5 0.0 3.1e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_61 PF03443.14 KIK64002.1 - 3.7e-41 141.3 0.0 5.6e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 KIK64003.1 - 2e-59 201.5 0.0 2.4e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3848 PF12959.7 KIK64003.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Glyoxal_oxid_N PF07250.11 KIK64004.1 - 3.2e-30 105.1 0.2 1.8e-14 53.5 0.0 5.1 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK64004.1 - 2.2e-24 85.6 0.4 4.9e-24 84.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.11 KIK64004.1 - 0.043 13.9 3.2 0.095 12.8 3.2 1.5 1 0 0 1 1 1 0 Podoplanin Kelch_4 PF13418.6 KIK64004.1 - 0.46 10.5 5.5 1.2 9.2 0.1 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain BING4CT PF08149.11 KIK64005.1 - 1.8e-27 94.9 0.0 4.7e-25 87.2 0.0 3.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KIK64005.1 - 1.2e-06 29.1 0.7 0.0016 19.2 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64005.1 - 0.0002 21.6 0.0 11 6.4 0.0 4.8 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK64005.1 - 0.067 11.7 0.0 5.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Sterol-sensing PF12349.8 KIK64007.1 - 0.044 13.6 0.2 0.094 12.6 0.2 1.5 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation TerC PF03741.16 KIK64008.1 - 0.0013 18.4 0.5 0.0064 16.2 0.2 1.9 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF4064 PF13273.6 KIK64008.1 - 0.015 15.6 0.7 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) GRIM-19 PF06212.12 KIK64008.1 - 0.061 13.3 0.6 0.15 12.0 0.0 1.9 3 0 0 3 3 3 0 GRIM-19 protein 7TM_GPCR_Srv PF10323.9 KIK64008.1 - 0.081 12.3 2.8 3.9 6.7 0.1 2.2 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2207 PF09972.9 KIK64008.1 - 0.12 11.1 1.9 0.86 8.3 1.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MscL PF01741.18 KIK64008.1 - 0.13 12.5 1.8 0.38 11.0 0.2 2.2 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF4834 PF16118.5 KIK64008.1 - 0.19 12.7 1.9 4.1 8.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) LapA_dom PF06305.11 KIK64008.1 - 0.87 9.4 6.5 2.4 8.0 0.7 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF202 PF02656.15 KIK64008.1 - 2.7 8.5 9.6 20 5.7 8.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) TAF PF02969.17 KIK64009.1 - 2.4e-23 82.1 0.8 4.2e-23 81.3 0.8 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KIK64009.1 - 1.1e-14 54.5 0.0 2.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KIK64009.1 - 3.8e-05 24.0 0.6 8e-05 23.0 0.6 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KIK64009.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated Diacid_rec PF05651.13 KIK64009.1 - 0.058 13.1 0.4 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition CBFD_NFYB_HMF PF00808.23 KIK64009.1 - 0.075 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAD_binding_3 PF01494.19 KIK64011.1 - 1.4e-22 80.5 0.0 2.6e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KIK64011.1 - 4e-06 26.0 0.0 0.0021 17.0 0.0 2.5 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KIK64011.1 - 0.0015 18.7 0.1 0.0034 17.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK64011.1 - 0.018 14.3 0.0 0.55 9.4 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK64011.1 - 0.019 14.2 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KIK64011.1 - 0.079 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase LANC_like PF05147.13 KIK64012.1 - 2e-32 112.2 0.0 2.9e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein ABC_tran PF00005.27 KIK64014.1 - 5.9e-19 68.9 0.0 1.2e-18 68.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK64014.1 - 2.3e-09 37.5 2.5 0.0005 20.0 0.5 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK64014.1 - 0.00024 20.8 0.2 0.00053 19.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK64014.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK64014.1 - 0.0067 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KIK64014.1 - 0.0072 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIK64014.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KIK64014.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIK64014.1 - 0.062 12.7 0.2 2 7.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KIK64014.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KIK64014.1 - 0.25 10.1 1.5 0.47 9.2 0.2 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class bZIP_1 PF00170.21 KIK64015.1 - 4.8e-08 33.0 6.4 9.4e-08 32.0 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK64015.1 - 7.4e-08 32.4 7.2 1.3e-07 31.6 7.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIK64015.1 - 0.56 10.8 9.7 0.12 12.9 6.0 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor Beta-lactamase PF00144.24 KIK64017.1 - 5e-34 118.0 0.0 7.9e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KIK64017.1 - 0.013 16.0 0.2 3.7 8.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3471) Y_phosphatase3 PF13350.6 KIK64018.1 - 4.7e-40 138.0 0.0 5.6e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIK64018.1 - 2.2e-08 33.9 0.1 6.9e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Apc15p PF05841.11 KIK64018.1 - 0.068 14.0 0.1 0.21 12.4 0.1 1.7 2 0 0 2 2 2 0 Apc15p protein Y_phosphatase PF00102.27 KIK64018.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UPF0016 PF01169.19 KIK64019.1 - 7e-42 141.6 20.2 7.2e-21 74.3 7.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 KIK64019.1 - 0.00063 19.5 3.7 0.001 18.8 0.0 2.3 2 1 0 2 2 2 1 Integral membrane protein TerC family LysE PF01810.18 KIK64019.1 - 0.0013 18.2 18.2 0.054 12.9 1.3 3.4 3 1 1 4 4 4 3 LysE type translocator Mntp PF02659.15 KIK64019.1 - 0.002 17.9 7.7 0.0055 16.5 0.2 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump RhlB PF12300.8 KIK64019.1 - 0.03 14.5 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB NnrS PF05940.12 KIK64019.1 - 0.075 12.4 11.5 0.14 11.5 4.3 2.2 2 0 0 2 2 2 0 NnrS protein DUF3995 PF13160.6 KIK64019.1 - 0.09 13.1 7.1 0.17 12.2 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Phage_holin_3_6 PF07332.11 KIK64019.1 - 0.17 11.9 0.1 0.17 11.9 0.1 3.0 2 2 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NAD_binding_4 PF07993.12 KIK64020.1 - 5.2e-34 117.6 0.0 9.4e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK64020.1 - 2e-30 105.8 0.0 2.9e-29 101.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIK64020.1 - 1.7e-06 27.7 0.0 4.1e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK64020.1 - 0.00085 19.6 0.1 0.0048 17.2 0.1 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KIK64020.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIK64020.1 - 0.066 12.3 0.0 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain CENP-H PF05837.12 KIK64021.1 - 0.00038 20.8 8.1 0.00038 20.8 8.1 6.5 1 1 6 7 7 7 2 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 KIK64021.1 - 0.00074 19.5 6.0 0.00074 19.5 6.0 7.8 5 2 2 8 8 8 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 KIK64021.1 - 0.0021 16.8 16.5 0.0021 16.8 16.5 3.1 1 1 2 3 3 3 1 AAA domain YabA PF06156.13 KIK64021.1 - 0.003 18.2 63.5 0.028 15.0 7.8 6.6 1 1 3 6 6 6 4 Initiation control protein YabA TPR_MLP1_2 PF07926.12 KIK64021.1 - 0.01 15.9 81.5 0.18 11.9 12.4 5.7 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KIK64021.1 - 0.012 16.1 21.9 0.012 16.1 21.9 4.3 1 1 2 4 4 4 0 Fez1 CENP-F_leu_zip PF10473.9 KIK64021.1 - 0.012 15.6 81.7 0.1 12.6 2.0 6.8 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_tail_NK PF16532.5 KIK64021.1 - 0.061 13.0 4.9 1.1 8.8 0.1 3.5 3 1 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales ADIP PF11559.8 KIK64021.1 - 0.098 12.7 85.1 0.25 11.4 12.0 6.6 1 1 5 6 6 5 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIK64021.1 - 0.29 10.5 56.2 2.3 7.5 20.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.19 KIK64021.1 - 0.53 8.0 76.9 0.91 7.2 32.0 2.2 1 1 1 2 2 2 0 Myosin tail HMMR_N PF15905.5 KIK64021.1 - 0.61 9.5 76.8 1.7 8.0 19.8 4.3 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal SNARE PF05739.19 KIK64021.1 - 1.6 8.8 4.4 21 5.2 0.5 2.8 2 0 0 2 2 2 0 SNARE domain DUF5082 PF16888.5 KIK64021.1 - 1.7 8.9 60.1 1.3 9.3 10.9 6.0 3 3 0 5 5 5 0 Domain of unknown function (DUF5082) Tektin PF03148.14 KIK64021.1 - 1.9 7.1 67.4 0.078 11.7 18.8 4.6 1 1 3 4 4 4 0 Tektin family PKcGMP_CC PF16808.5 KIK64021.1 - 2 8.4 24.5 1.2 9.0 0.4 6.9 7 1 1 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KIK64021.1 - 7.5 5.3 79.9 0.017 14.0 22.4 4.6 1 1 2 4 4 4 0 Spc7 kinetochore protein HiaBD2 PF15403.6 KIK64021.1 - 9.2 6.8 9.7 17 5.9 0.6 3.2 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) PspA_IM30 PF04012.12 KIK64021.1 - 9.3 5.8 63.6 0.02 14.5 3.8 4.8 2 1 1 4 4 4 0 PspA/IM30 family Oxidored_FMN PF00724.20 KIK64023.1 - 8.3e-68 229.2 0.0 9.7e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KIK64023.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Dus PF01207.17 KIK64023.1 - 0.23 10.5 0.1 0.57 9.2 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Homeodomain PF00046.29 KIK64024.1 - 0.007 16.2 0.5 0.0091 15.8 0.5 1.1 1 0 0 1 1 1 1 Homeodomain NAD_binding_4 PF07993.12 KIK64025.1 - 3e-30 105.3 0.0 5.2e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK64025.1 - 2.6e-26 92.2 0.0 5.8e-26 91.0 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIK64025.1 - 0.00025 20.6 0.0 0.00067 19.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK64025.1 - 0.015 15.7 0.3 0.15 12.4 0.3 2.5 1 1 0 1 1 1 0 Phosphopantetheine attachment site AlaDh_PNT_N PF05222.15 KIK64026.1 - 3.7e-26 92.0 0.0 5.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIK64026.1 - 0.00026 20.4 0.0 0.0015 17.9 0.0 2.0 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CENP-F_leu_zip PF10473.9 KIK64027.1 - 6e-06 26.3 79.7 0.067 13.2 9.6 7.2 1 1 6 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 KIK64027.1 - 0.0006 19.9 6.5 0.0006 19.9 6.5 6.8 3 2 4 8 8 8 1 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 KIK64027.1 - 0.00084 19.4 83.6 0.12 12.4 13.4 7.1 1 1 5 6 6 6 3 TPR/MLP1/MLP2-like protein GAS PF13851.6 KIK64027.1 - 0.0014 18.0 8.2 0.0014 18.0 8.2 5.6 1 1 5 6 6 6 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KIK64027.1 - 0.012 14.5 78.0 0.015 14.2 14.2 5.2 1 1 4 5 5 5 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KIK64027.1 - 0.025 14.4 70.9 0.54 10.0 12.2 5.2 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 KIK64027.1 - 0.074 12.6 72.6 0.11 12.1 29.1 5.0 1 1 2 3 3 3 0 Intermediate filament protein Golgin_A5 PF09787.9 KIK64027.1 - 0.19 11.1 78.9 0.074 12.5 13.9 4.2 1 1 2 4 4 4 0 Golgin subfamily A member 5 DUF2935 PF11155.8 KIK64027.1 - 0.85 10.0 9.4 2.1 8.7 0.9 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF2935) DUF3450 PF11932.8 KIK64027.1 - 2.7 7.3 68.5 1.1 8.5 4.8 5.9 1 1 2 5 5 5 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KIK64027.1 - 2.8 8.5 85.3 5.5 7.5 11.3 7.1 1 1 6 7 7 6 0 Apg6 coiled-coil region DUF2046 PF09755.9 KIK64027.1 - 5.6 6.1 65.6 2.3 7.4 26.4 3.4 1 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Lectin_N PF03954.14 KIK64027.1 - 6.2 6.6 48.2 2.4 7.9 2.5 6.7 4 2 3 7 7 7 0 Hepatic lectin, N-terminal domain CDO_I PF05995.12 KIK64027.1 - 8.9 5.6 7.6 0.45 9.8 0.1 2.7 4 0 0 4 4 4 0 Cysteine dioxygenase type I VIT PF08487.10 KIK64028.1 - 1.2e-26 93.1 0.1 2.7e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK64028.1 - 2.6e-24 86.0 0.0 5.2e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK64028.1 - 1.3e-14 54.8 0.0 3.2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK64028.1 - 5.5e-10 39.8 0.0 2e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIK64028.1 - 2.7e-07 30.2 0.1 6.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 KIK64028.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain VIT_2 PF13757.6 KIK64028.1 - 0.027 14.4 0.0 0.08 12.8 0.0 1.9 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain NAD_binding_4 PF07993.12 KIK64029.1 - 4e-33 114.7 0.0 8.3e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK64029.1 - 1.4e-30 106.3 0.0 2.3e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK64029.1 - 6.9e-08 32.3 0.0 2.6e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK64029.1 - 0.0044 16.9 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIK64029.1 - 0.038 14.4 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KIK64029.1 - 0.096 12.6 0.0 1.6 8.6 0.0 2.4 1 1 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KIK64029.1 - 0.16 11.0 0.0 0.54 9.2 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KIK64029.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UQ_con PF00179.26 KIK64030.1 - 6.6e-49 165.2 0.0 7.4e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK64030.1 - 0.00048 19.8 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIK64030.1 - 0.015 15.1 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KIK64030.1 - 0.087 13.1 0.2 0.12 12.7 0.2 1.4 1 1 0 1 1 1 0 RWD domain NAT PF04768.13 KIK64031.1 - 9.1e-47 158.9 0.0 1.4e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KIK64031.1 - 2.3e-25 89.6 0.2 7e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KIK64031.1 - 4e-25 88.6 0.0 9.9e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KIK64031.1 - 3.7e-05 23.9 0.0 7.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Metallophos PF00149.28 KIK64033.1 - 3e-33 116.1 0.0 4.5e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.15 KIK64034.1 - 7e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain AMP-binding PF00501.28 KIK64035.1 - 1.2e-31 109.7 0.0 2.6e-31 108.7 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK64035.1 - 1.2e-30 106.5 0.0 2.9e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK64035.1 - 4.8e-07 29.5 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK64035.1 - 0.025 14.5 0.0 0.096 12.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding PP-binding PF00550.25 KIK64035.1 - 0.094 13.1 0.0 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 KIK64035.1 - 0.15 12.5 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.17 KIK64037.1 - 2.1e-53 181.3 0.0 2.8e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64037.1 - 7.1e-35 120.6 0.0 1e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK64037.1 - 0.0087 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK64037.1 - 0.024 14.2 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Peptidase_C54 PF03416.19 KIK64038.1 - 6.1e-99 330.9 0.0 8e-99 330.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 UDG PF03167.19 KIK64039.1 - 1.4e-16 60.9 0.0 1.2e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily ArAE_2 PF10334.9 KIK64040.1 - 4.1e-52 177.3 0.0 8.5e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KIK64040.1 - 7.3e-47 160.5 0.1 8.9e-43 147.0 0.1 2.6 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KIK64040.1 - 1.2e-11 44.9 12.9 1.2e-11 44.9 12.9 3.6 3 1 0 3 3 3 1 Fusaric acid resistance protein-like SH3-WW_linker PF16618.5 KIK64041.1 - 0.0055 17.2 0.4 0.0068 16.9 0.4 1.1 1 0 0 1 1 1 1 Linker region between SH3 and WW domains on ARHGAP12 CxC1 PF18802.1 KIK64042.1 - 0.052 13.7 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases DUF659 PF04937.15 KIK64042.1 - 0.081 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KIK64043.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_hydro_31 PF01055.26 KIK64044.1 - 1.8e-139 465.7 0.1 2.3e-139 465.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK64044.1 - 8.9e-29 100.0 0.1 1.6e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK64044.1 - 2.5e-06 27.7 0.1 6.5e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like ECH_1 PF00378.20 KIK64045.1 - 4.6e-36 124.4 0.1 7e-35 120.5 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK64045.1 - 3.8e-18 66.1 0.0 2.7e-15 56.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HSP70 PF00012.20 KIK64046.1 - 5.1e-60 203.3 3.6 2.3e-45 154.9 0.3 2.7 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KIK64046.1 - 2.1e-09 36.6 0.2 8.1e-09 34.7 0.2 1.8 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KIK64046.1 - 0.019 14.0 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Pkinase_Tyr PF07714.17 KIK64047.1 - 2.8e-28 98.9 0.0 3.3e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64047.1 - 4e-25 88.7 0.0 4.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK64047.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK64047.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_31 PF01055.26 KIK64048.1 - 4.6e-139 464.4 0.1 5.8e-139 464.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK64048.1 - 3.4e-29 101.4 0.1 6.2e-29 100.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK64048.1 - 2.2e-06 27.9 0.1 6.7e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_61 PF03443.14 KIK64050.1 - 7.3e-50 169.8 0.0 9.9e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SR-25 PF10500.9 KIK64050.1 - 0.0075 15.9 6.7 0.013 15.2 6.7 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 KIK64050.1 - 0.16 10.0 4.2 0.18 9.9 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM171 PF15471.6 KIK64050.1 - 0.29 10.1 3.7 0.51 9.3 3.7 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Pectinesterase PF01095.19 KIK64052.1 - 1.2e-34 119.4 0.7 1.5e-34 119.0 0.7 1.0 1 0 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.19 KIK64053.1 - 1e-37 129.5 3.8 1.3e-37 129.2 3.8 1.1 1 0 0 1 1 1 1 Pectinesterase Oxysterol_BP PF01237.18 KIK64054.1 - 5.5e-133 443.4 0.0 9.4e-133 442.6 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 KIK64054.1 - 1.5e-13 50.7 0.2 3.3e-06 27.3 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK64054.1 - 1.6e-13 51.0 0.0 5.9e-11 42.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK64054.1 - 2.9e-10 39.5 0.1 0.0078 16.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 KIK64054.1 - 3.2e-10 40.5 0.0 9.2e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 KIK64054.1 - 4.7e-09 36.6 0.1 1.2e-05 25.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK64054.1 - 1.1e-08 35.2 1.2 0.0024 18.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KIK64054.1 - 8e-07 29.3 0.5 2.5e-06 27.7 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KIK64054.1 - 1.7e-05 25.1 0.9 6.6e-05 23.3 0.5 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3829 PF12889.7 KIK64054.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) SOG2 PF10428.9 KIK64055.1 - 0.93 8.6 27.4 1.4 8.0 27.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KIK64055.1 - 7.5 6.4 14.4 12 5.7 14.4 1.3 1 0 0 1 1 1 0 SPX domain dCMP_cyt_deam_1 PF00383.23 KIK64056.1 - 5.2e-23 80.8 0.0 6.7e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK64056.1 - 1.6e-20 73.3 0.0 2.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KIK64056.1 - 0.00034 20.7 0.0 0.00086 19.4 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KIK64056.1 - 0.0027 17.8 0.0 0.068 13.3 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KIK64056.1 - 0.0049 16.9 0.0 0.042 13.9 0.0 1.9 1 1 1 2 2 2 1 APOBEC2 Bd3614-deam PF14439.6 KIK64056.1 - 0.0089 16.1 0.4 0.042 13.9 0.4 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase NAD2 PF18782.1 KIK64056.1 - 0.011 15.9 0.0 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 KIK64056.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 KIK64056.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 APOBEC-like N-terminal domain NAP PF00956.18 KIK64057.1 - 1.6e-58 198.0 1.5 1.6e-58 198.0 1.5 1.3 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TauD PF02668.16 KIK64058.1 - 7.5e-58 196.4 2.5 7.5e-58 196.4 2.5 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2834 PF11196.8 KIK64059.1 - 2.2e-07 31.1 17.2 0.00017 21.8 6.7 3.6 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) Acetyltransf_3 PF13302.7 KIK64061.1 - 1.4e-19 71.1 0.0 2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK64061.1 - 2.4e-07 30.5 0.0 1.6e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK64061.1 - 0.0074 16.2 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KIK64061.1 - 0.036 14.3 0.0 1.9 8.7 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK64061.1 - 0.042 14.3 0.0 0.097 13.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK64061.1 - 0.078 13.1 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK64062.1 - 4.2e-12 46.3 0.0 5.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK64062.1 - 1.3e-11 44.5 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK64062.1 - 2.1e-11 44.1 0.0 3.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK64062.1 - 3.9e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIK64062.1 - 0.00053 20.1 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK64062.1 - 0.0014 19.3 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK64062.1 - 0.0019 18.3 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KIK64062.1 - 0.016 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF2312 PF10073.9 KIK64062.1 - 0.094 12.4 0.2 9.5 5.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Tugs PF17840.1 KIK64062.1 - 0.27 11.5 0.5 0.6 10.3 0.1 1.8 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain NAD_binding_8 PF13450.6 KIK64063.1 - 1.1e-13 51.1 0.5 1e-12 48.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK64063.1 - 8.5e-06 25.8 0.1 5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KIK64063.1 - 1.1e-05 24.4 0.2 0.019 13.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KIK64063.1 - 2.3e-05 24.9 0.1 0.1 13.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK64063.1 - 2.5e-05 24.1 0.0 0.00029 20.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK64063.1 - 7.9e-05 22.0 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK64063.1 - 0.00029 20.1 0.0 0.00058 19.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KIK64063.1 - 0.0037 16.6 0.1 0.059 12.6 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KIK64063.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK64063.1 - 0.028 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KIK64063.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KIK64063.1 - 0.15 11.4 0.0 0.71 9.2 0.0 2.0 2 1 0 2 2 2 0 ThiF family Sacchrp_dh_NADP PF03435.18 KIK64063.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Aldo_ket_red PF00248.21 KIK64065.1 - 2.6e-50 171.3 0.0 3e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_108 PF05838.12 KIK64065.1 - 0.057 13.9 0.9 14 6.2 0.1 2.7 2 1 0 2 2 2 0 Glycosyl hydrolase 108 TSNAXIP1_N PF15739.5 KIK64065.1 - 0.14 12.5 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Glyco_hydro_61 PF03443.14 KIK64066.1 - 2.4e-53 181.1 0.1 3.6e-53 180.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cullin PF00888.22 KIK64068.1 - 0.00096 17.9 0.0 0.00096 17.9 0.0 1.0 1 0 0 1 1 1 1 Cullin family AnfG_VnfG PF03139.15 KIK64068.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Glyco_hydro_31 PF01055.26 KIK64069.1 - 2.7e-141 471.7 0.1 3.5e-141 471.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK64069.1 - 1.4e-31 109.1 0.0 3e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK64069.1 - 9.6e-06 25.8 0.1 3.3e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Zn_clus PF00172.18 KIK64071.1 - 4.6e-08 33.1 11.0 7.1e-08 32.4 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VIT PF08487.10 KIK64074.1 - 5e-27 94.3 0.0 1.2e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK64074.1 - 5.2e-23 81.7 0.0 1.1e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK64074.1 - 1e-12 48.7 0.0 2.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK64074.1 - 1.5e-08 35.2 0.0 5.9e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIK64074.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 KIK64074.1 - 0.0049 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain Nucleoporin_FG PF13634.6 KIK64074.1 - 0.013 16.3 8.6 0.07 14.0 4.2 2.9 2 0 0 2 2 2 0 Nucleoporin FG repeat region HMG_box PF00505.19 KIK64075.1 - 1.2e-14 54.4 0.0 2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK64075.1 - 2.9e-05 24.6 0.0 6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KIK64075.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Aldo_ket_red PF00248.21 KIK64076.1 - 1.9e-31 109.3 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cellulase PF00150.18 KIK64077.1 - 1.5e-44 152.5 0.1 1.8e-44 152.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CHCH PF06747.13 KIK64078.1 - 0.00054 20.0 7.6 0.00078 19.5 7.6 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KIK64078.1 - 0.00075 19.7 1.8 0.001 19.2 1.8 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KIK64078.1 - 0.0045 17.3 2.1 0.0091 16.3 2.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KIK64078.1 - 0.075 13.4 2.9 0.13 12.7 2.9 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Ribonuc_red_sm PF00268.21 KIK64079.1 - 6.9e-121 403.0 1.1 8.7e-121 402.7 1.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PRA1 PF03208.19 KIK64079.1 - 0.17 11.5 0.2 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 PRA1 family protein Pox_Ag35 PF03286.14 KIK64079.1 - 0.86 9.4 5.8 1.4 8.7 5.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHquinase_II PF01220.19 KIK64080.1 - 2.5e-59 198.9 0.0 3.1e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peripla_BP_1 PF00532.21 KIK64080.1 - 0.053 12.9 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Alpha-L-AF_C PF06964.12 KIK64082.1 - 2.5e-29 102.6 0.0 3.9e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79n PF03662.14 KIK64082.1 - 0.002 17.1 0.2 0.015 14.2 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_44 PF12891.7 KIK64082.1 - 0.041 13.8 0.7 0.13 12.2 0.4 1.9 2 1 0 2 2 2 0 Glycoside hydrolase family 44 Sugar_tr PF00083.24 KIK64083.1 - 3.4e-107 359.1 19.8 4e-107 358.9 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK64083.1 - 3e-26 92.2 35.2 2.5e-22 79.3 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD-oxidase_C PF02913.19 KIK64084.1 - 3.3e-54 184.2 0.0 7.9e-54 182.9 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK64084.1 - 4.7e-30 104.1 0.1 8e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain PilZ PF07238.14 KIK64084.1 - 0.03 14.6 0.0 14 6.0 0.0 2.7 2 0 0 2 2 2 0 PilZ domain Aldolase_II PF00596.21 KIK64085.1 - 4.1e-15 56.2 0.3 2.1e-14 53.9 0.3 1.9 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldolase_II PF00596.21 KIK64088.1 - 6.2e-17 62.1 0.1 3.4e-16 59.7 0.1 1.9 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydantoinase_B PF02538.14 KIK64089.1 - 4.3e-204 678.7 0.1 5.8e-204 678.3 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KIK64089.1 - 1.2e-96 323.4 0.2 4.3e-96 321.6 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIK64089.1 - 4.1e-59 199.3 0.0 2.5e-56 190.2 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 KIK64090.1 - 4.8e-31 108.0 29.1 4.8e-31 108.0 29.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 KIK64090.1 - 0.05 11.9 21.5 0.12 10.6 9.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3040 PF11239.8 KIK64090.1 - 2.4 8.5 10.7 5.5 7.3 0.7 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Fungal_trans PF04082.18 KIK64092.1 - 5e-15 55.3 0.4 1e-11 44.4 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Cu-oxidase PF00394.22 KIK64093.1 - 1e-45 155.7 0.0 3.7e-41 140.9 0.0 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK64093.1 - 7.6e-40 135.8 3.1 9e-35 119.4 0.1 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK64093.1 - 9.5e-38 128.9 0.6 1.5e-34 118.5 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase GPR_Gpa2_C PF11970.8 KIK64094.1 - 1.8 8.7 4.9 0.52 10.4 0.2 2.4 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term AMP-binding PF00501.28 KIK64095.1 - 9.6e-86 288.0 0.0 3.3e-85 286.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK64095.1 - 4.2e-07 30.9 0.4 9.3e-06 26.5 0.4 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AA_permease_2 PF13520.6 KIK64096.1 - 2.3e-62 211.2 52.6 2.7e-62 211.0 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK64096.1 - 7.8e-14 51.1 44.5 1.5e-13 50.2 44.5 1.4 1 1 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 KIK64098.1 - 2.3e-06 27.4 0.1 6.7e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK64098.1 - 2.3e-06 27.3 0.0 6.4e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain HLH PF00010.26 KIK64100.1 - 5.5e-11 42.3 0.6 9.5e-11 41.5 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain F1F0-ATPsyn_F PF10791.9 KIK64101.1 - 2.6e-28 98.3 0.0 3.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi GPHR_N PF12537.8 KIK64104.1 - 0.06 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal p450 PF00067.22 KIK64105.1 - 7.2e-71 239.3 0.0 8.1e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEC1 PF15859.5 KIK64105.1 - 0.045 13.8 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Deleted in esophageal cancer 1 family ICMT PF04140.14 KIK64108.1 - 5.5e-13 49.2 1.3 6.4e-12 45.7 1.3 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK64108.1 - 3.1e-10 40.4 3.1 3.3e-09 37.1 0.1 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK64108.1 - 2e-09 36.7 0.4 2.9e-09 36.2 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SUR7 PF06687.12 KIK64108.1 - 0.46 10.1 3.7 0.44 10.2 1.2 1.9 2 0 0 2 2 2 0 SUR7/PalI family Aldedh PF00171.22 KIK64109.1 - 1.5e-126 422.6 0.4 1.7e-126 422.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK64109.1 - 0.0035 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SPC12 PF06645.13 KIK64111.1 - 3.2e-24 84.8 0.5 3.7e-24 84.6 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Pkinase PF00069.25 KIK64112.1 - 1.9e-63 214.3 0.0 1.4e-62 211.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64112.1 - 3.6e-35 121.5 0.0 1.2e-34 119.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KIK64112.1 - 1.1e-17 63.5 0.1 1.9e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KIK64112.1 - 9e-07 28.5 0.3 1.5e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK64112.1 - 3.6e-05 23.2 0.0 8.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK64112.1 - 0.00021 21.3 0.9 0.00077 19.4 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK64112.1 - 0.00025 20.1 0.1 0.0004 19.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 KIK64112.1 - 0.057 13.0 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Sugar_tr PF00083.24 KIK64113.1 - 2.9e-97 326.4 23.1 3.3e-97 326.2 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK64113.1 - 3.7e-16 59.0 40.5 9.4e-12 44.5 15.2 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 KIK64114.1 - 6e-51 173.8 0.1 8e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aa_trans PF01490.18 KIK64115.1 - 1.9e-32 112.5 38.6 2.3e-32 112.3 38.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EBV-NA1 PF02905.14 KIK64115.1 - 0.09 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Pkinase PF00069.25 KIK64116.1 - 6.5e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KIK64116.1 - 0.0052 16.4 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KIK64116.1 - 0.087 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIK64116.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.7 KIK64119.1 - 0.04 13.8 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 F-box-like DcuA_DcuB PF03605.14 KIK64119.1 - 0.058 12.3 1.8 0.17 10.8 1.7 1.6 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter F-box-like PF12937.7 KIK64121.1 - 1e-06 28.5 0.1 3e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 KIK64122.1 - 4.6e-12 45.5 0.4 1.3e-11 44.0 0.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK64122.1 - 0.00076 19.6 9.4 0.0012 18.9 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E3_UbLigase_R4 PF13764.6 KIK64122.1 - 0.059 11.5 0.1 0.088 11.0 0.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 GIDA PF01134.22 KIK64123.1 - 1.1e-155 518.6 0.0 1.3e-155 518.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KIK64123.1 - 3.3e-66 223.5 0.0 4.5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KIK64123.1 - 1.7e-07 31.0 0.7 2.9e-07 30.2 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK64123.1 - 7e-06 25.5 1.7 0.00014 21.2 1.2 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK64123.1 - 2.2e-05 23.8 0.6 0.0001 21.6 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK64123.1 - 0.00071 18.4 1.0 0.017 13.8 0.3 2.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KIK64123.1 - 0.0013 18.1 1.5 0.0027 17.0 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KIK64123.1 - 0.0014 18.3 2.2 0.28 10.7 0.9 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK64123.1 - 0.017 15.7 0.2 0.041 14.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK64123.1 - 0.055 13.7 1.2 0.16 12.3 1.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK64123.1 - 0.11 11.7 0.4 0.22 10.7 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK64123.1 - 0.15 11.3 0.1 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 KIK64124.1 - 2.2e-21 75.8 0.8 4.5e-21 74.8 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK64124.1 - 3.4e-11 43.2 0.0 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK64124.1 - 0.00032 20.1 0.1 0.00055 19.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK64124.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIK64124.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIK64124.1 - 0.026 15.0 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 KIK64124.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 KIK64124.1 - 0.1 13.4 0.0 0.55 11.1 0.0 2.1 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Pox_polyA_pol PF03296.13 KIK64127.1 - 0.12 12.2 1.8 0.21 11.5 1.8 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain DUF5368 PF17336.2 KIK64128.1 - 3.7 7.8 8.1 0.26 11.5 0.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5368) DUF4010 PF13194.6 KIK64132.1 - 0.0038 16.9 1.2 0.0069 16.1 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) Mito_carr PF00153.27 KIK64133.1 - 3.4e-20 71.7 8.0 9.6e-08 31.8 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 KIK64134.1 - 1.3e-22 79.8 3.4 2e-22 79.1 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK64134.1 - 3.4e-15 56.2 0.1 9.5e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK64134.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK64134.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIK64135.1 - 1.6e-19 70.3 0.0 1.7e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK64135.1 - 7.8e-08 32.4 0.5 2e-07 31.1 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK64135.1 - 3.9e-06 26.7 0.3 6.1e-05 22.8 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK64135.1 - 0.0001 21.6 0.5 0.00017 20.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK64135.1 - 0.0006 19.1 0.7 0.0061 15.8 1.3 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK64135.1 - 0.013 14.6 0.2 0.018 14.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIK64135.1 - 0.034 13.4 1.2 0.064 12.5 1.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK64135.1 - 0.037 13.3 0.3 0.06 12.6 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KIK64135.1 - 0.069 13.7 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIK64135.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 KIK64135.1 - 0.15 10.7 0.6 0.23 10.1 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK64135.1 - 0.19 11.7 0.3 0.46 10.5 0.3 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TFIIS_M PF07500.14 KIK64136.1 - 9.8e-33 113.0 0.7 9.8e-33 113.0 0.7 2.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KIK64136.1 - 3.4e-18 65.2 9.7 5.6e-18 64.5 9.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KIK64136.1 - 6.5e-10 38.9 0.7 6.5e-10 38.9 0.7 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ribosomal_S10 PF00338.22 KIK64136.1 - 0.049 13.9 1.7 0.13 12.5 1.7 1.8 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e MMU163 PF17119.5 KIK64136.1 - 0.63 9.1 4.6 0.19 10.9 0.9 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis WD40 PF00400.32 KIK64137.1 - 2.2e-43 145.4 18.8 3.3e-08 34.1 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64137.1 - 2.6e-05 24.5 0.4 0.78 10.1 0.1 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK64137.1 - 0.0069 15.1 0.6 3 6.4 0.0 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ricin_B_lectin PF00652.22 KIK64137.1 - 0.016 15.5 0.0 0.37 11.1 0.0 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain WD40_like PF17005.5 KIK64137.1 - 0.026 13.8 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain Ribosomal_L7Ae PF01248.26 KIK64140.1 - 3.4e-21 74.8 0.5 5.8e-21 74.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TPR_2 PF07719.17 KIK64143.1 - 2.2e-39 130.4 16.0 5.4e-05 23.0 0.0 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIK64143.1 - 5.4e-37 124.1 20.7 3.4e-06 26.6 0.0 11.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 KIK64143.1 - 1e-25 90.1 3.8 1.7e-06 28.5 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK64143.1 - 7e-22 75.8 13.1 0.00063 19.8 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIK64143.1 - 1.1e-21 75.5 4.0 5e-05 23.4 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK64143.1 - 1.8e-21 76.2 8.1 1.5e-06 28.4 0.0 7.7 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK64143.1 - 3.1e-20 72.4 13.6 0.00014 22.3 0.0 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK64143.1 - 1.9e-19 69.0 10.9 1.2e-07 31.3 0.0 7.5 6 1 2 8 8 7 4 TPR repeat TPR_14 PF13428.6 KIK64143.1 - 2.1e-18 65.4 6.4 4e-06 27.2 0.0 8.7 6 3 5 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK64143.1 - 9.4e-16 56.6 3.5 0.029 14.4 0.1 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK64143.1 - 4.2e-13 49.2 1.9 0.00052 20.1 0.0 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK64143.1 - 5.2e-12 45.8 7.9 0.0016 18.6 0.0 5.3 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KIK64143.1 - 2.2e-10 40.4 0.4 1.1e-06 28.3 0.3 2.8 2 1 1 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 KIK64143.1 - 9.6e-09 35.3 13.6 0.035 14.7 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_21 PF09976.9 KIK64143.1 - 7.9e-07 29.0 10.6 0.08 12.6 0.0 5.6 3 2 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KIK64143.1 - 4.9e-05 23.1 11.7 5.3 7.0 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK64143.1 - 0.00026 20.3 4.4 0.0054 16.0 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 KIK64143.1 - 0.00035 19.6 0.2 0.00035 19.6 0.2 3.6 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KIK64143.1 - 0.0006 20.2 3.9 11 7.0 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 KIK64143.1 - 0.0025 16.3 0.2 0.0086 14.5 0.2 1.9 2 0 0 2 2 2 1 Spermatogenesis-associated, N-terminal DUF4810 PF16068.5 KIK64143.1 - 0.011 16.2 2.1 26 5.5 0.0 4.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4810) BTAD PF03704.17 KIK64143.1 - 0.027 14.9 4.7 3 8.2 0.0 4.2 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 KIK64143.1 - 0.036 14.4 12.6 0.82 10.1 0.0 6.3 4 1 3 7 7 7 0 Tetratricopeptide repeat PDCD2_C PF04194.13 KIK64143.1 - 0.052 13.6 2.8 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain PPR PF01535.20 KIK64143.1 - 0.071 13.4 0.0 18 5.9 0.0 3.3 2 0 0 2 2 2 0 PPR repeat SHNi-TPR PF10516.9 KIK64143.1 - 0.11 12.0 3.9 4.8 6.7 0.1 4.2 4 0 0 4 4 4 0 SHNi-TPR Fis1_TPR_C PF14853.6 KIK64143.1 - 0.48 10.5 3.6 6.2 7.0 0.0 4.1 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 KIK64143.1 - 0.67 10.7 5.5 8.3 7.2 0.0 4.6 5 0 0 5 5 3 0 Sel1 repeat DUF456 PF04306.13 KIK64145.1 - 0.0091 16.3 0.6 0.012 16.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Protocadherin PF08374.11 KIK64145.1 - 0.11 12.5 0.9 0.12 12.4 0.9 1.1 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 KIK64145.1 - 0.24 11.3 2.2 0.28 11.1 2.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family ELP6 PF09807.9 KIK64146.1 - 7.4e-17 61.6 0.0 1.9e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 KIK64146.1 - 4.7e-05 23.0 0.5 7.9e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 Elongator subunit Iki1 PAXNEB PF05625.11 KIK64146.1 - 0.004 16.3 0.4 0.0049 16.1 0.4 1.1 1 0 0 1 1 1 1 PAXNEB protein DUF835 PF05763.12 KIK64146.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF835) EutK_C PF16365.5 KIK64147.1 - 0.012 15.7 2.0 6.3 6.9 0.1 3.8 1 1 3 5 5 5 0 Ethanolamine utilization protein EutK C-terminus PH_RBD PF12068.8 KIK64147.1 - 0.024 14.1 3.1 2.1 7.8 0.1 2.9 1 1 1 2 2 2 0 Rab-binding domain (RBD) Hemerythrin PF01814.23 KIK64148.1 - 1.1e-07 32.6 0.7 1.8e-07 31.8 0.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_3_C PF01915.22 KIK64152.1 - 3.2e-45 154.6 0.0 5.4e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK64152.1 - 3.5e-38 131.8 0.0 5.2e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK64152.1 - 3.3e-22 78.4 0.0 6.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Diphthamide_syn PF01866.17 KIK64153.1 - 8.8e-87 291.3 0.1 2.3e-85 286.7 0.1 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein WD40 PF00400.32 KIK64154.1 - 5.5e-146 470.1 65.4 1.1e-09 38.7 0.1 17.7 17 0 0 17 17 17 17 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64154.1 - 9.6e-56 186.1 14.0 0.024 14.9 0.0 16.4 2 2 14 16 16 16 15 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK64154.1 - 6.8e-21 73.7 4.2 0.86 9.6 0.0 14.6 16 0 0 16 16 15 3 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KIK64154.1 - 2.5e-13 50.1 25.5 1.5 9.4 0.0 13.1 1 1 14 16 16 16 5 PQQ-like domain Ge1_WD40 PF16529.5 KIK64154.1 - 9.4e-13 47.8 4.9 1.1 8.1 0.0 12.1 11 4 4 15 15 15 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK64154.1 - 2.2e-12 46.4 7.8 2 6.9 0.0 12.1 10 2 4 14 14 14 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK64154.1 - 2.3e-12 46.8 0.0 0.14 11.4 0.0 8.4 8 3 0 9 9 9 1 WD40-like domain Cytochrom_D1 PF02239.16 KIK64154.1 - 4.4e-07 28.8 0.0 1.1 7.7 0.0 5.7 2 2 3 6 6 6 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KIK64154.1 - 1.1e-06 28.1 17.4 11 5.8 0.0 11.6 12 0 0 12 12 12 1 Proteasome subunit A N-terminal signature Frtz PF11768.8 KIK64154.1 - 6.8e-05 21.4 0.0 1.4e+02 0.6 0.0 8.7 12 1 1 13 13 13 0 WD repeat-containing and planar cell polarity effector protein Fritz MMS1_N PF10433.9 KIK64154.1 - 0.00046 19.0 0.0 0.7 8.5 0.0 4.9 3 2 2 5 5 5 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term NYD-SP12_N PF15015.6 KIK64154.1 - 0.001 17.6 0.0 56 1.9 0.0 6.7 5 3 5 10 10 10 0 Spermatogenesis-associated, N-terminal DUF5122 PF17164.4 KIK64154.1 - 0.013 15.8 9.0 95 3.4 0.0 8.0 8 0 0 8 8 8 0 Domain of unknown function (DUF5122) beta-propeller nos_propeller PF18764.1 KIK64154.1 - 0.02 14.8 5.1 59 3.7 0.0 6.4 7 0 0 7 7 7 0 Nitrous oxide reductase propeller repeat Cuticle_4 PF15955.5 KIK64154.1 - 0.34 11.6 22.3 1e+02 3.7 0.0 10.3 12 0 0 12 12 12 0 Cuticle protein Glyco_hydro_3_C PF01915.22 KIK64157.1 - 9.9e-11 42.0 0.0 1e-10 41.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Chorein_N PF12624.7 KIK64158.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 zf-C3HC4_2 PF13923.6 KIK64159.1 - 0.0028 17.5 2.7 0.0067 16.3 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK64159.1 - 0.0075 16.6 3.7 0.016 15.5 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK64159.1 - 0.013 15.3 3.6 0.031 14.2 3.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KIK64159.1 - 0.016 15.4 0.6 0.023 14.8 0.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KIK64159.1 - 0.027 14.2 0.8 0.046 13.5 0.4 1.7 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KIK64159.1 - 0.058 13.4 2.9 0.14 12.1 2.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.32 KIK64161.1 - 2.6e-56 186.3 25.2 2.3e-10 40.9 0.8 6.0 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64161.1 - 8.2e-25 86.9 0.1 4.5e-05 23.7 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64161.1 - 6.5e-13 48.3 1.5 0.0015 17.6 0.1 5.8 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK64161.1 - 3.1e-11 42.9 5.8 0.035 14.1 0.0 5.8 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK64161.1 - 2.7e-10 40.4 0.0 6.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK64161.1 - 8e-09 34.7 0.7 0.43 9.2 0.0 4.6 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Frtz PF11768.8 KIK64161.1 - 1.3e-06 27.1 0.0 0.032 12.5 0.0 4.0 3 2 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK64161.1 - 3.2e-06 26.7 0.0 0.035 13.4 0.0 3.5 2 2 1 3 3 3 2 WD40-like domain Gmad1 PF10647.9 KIK64161.1 - 1.3e-05 25.1 1.0 0.0099 15.7 0.0 3.4 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 KIK64161.1 - 0.00015 21.5 1.1 0.0024 17.5 1.0 2.5 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 KIK64161.1 - 0.0026 18.2 1.3 33 5.1 0.0 4.6 4 1 2 6 6 5 0 PQQ-like domain GspH PF12019.8 KIK64161.1 - 0.0043 17.5 1.1 4.9 7.6 0.2 3.8 1 1 2 3 3 3 1 Type II transport protein GspH Peptidase_S9_N PF02897.15 KIK64161.1 - 0.0064 15.3 0.0 8.5 5.0 0.0 3.7 1 1 2 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Me-amine-dh_H PF06433.11 KIK64161.1 - 0.0094 14.9 0.0 1.4 7.7 0.0 2.6 1 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) PALB2_WD40 PF16756.5 KIK64161.1 - 0.023 13.6 0.0 1 8.2 0.0 3.0 1 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 KIK64161.1 - 0.035 13.4 0.6 11 5.3 0.0 3.8 2 2 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK64161.1 - 0.048 13.6 0.0 66 3.7 0.0 4.2 5 0 0 5 5 5 0 PQQ enzyme repeat Utp8 PF10395.9 KIK64161.1 - 0.073 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Utp8 family WD40_3 PF15911.5 KIK64161.1 - 0.079 13.0 0.1 3.6 7.7 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KIK64161.1 - 0.095 12.4 11.4 23 4.8 0.0 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature ROQ_II PF18386.1 KIK64161.1 - 0.12 12.3 0.0 40 4.1 0.0 3.1 3 0 0 3 3 3 0 Roquin II domain GCV_T_C PF08669.11 KIK64161.1 - 0.12 12.3 1.6 20 5.2 0.0 3.8 4 1 0 5 5 4 0 Glycine cleavage T-protein C-terminal barrel domain rOmpB PF12334.8 KIK64161.1 - 0.12 11.8 0.4 7.1 6.0 0.1 3.1 3 1 0 3 3 3 0 Rickettsia outer membrane protein B CHAP PF05257.16 KIK64161.1 - 0.49 11.0 3.9 0.25 12.0 0.5 2.2 2 1 0 2 2 2 0 CHAP domain Pkinase PF00069.25 KIK64163.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK64163.1 - 0.013 15.5 0.1 0.19 11.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.11 KIK64163.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) AvrPto PF11592.8 KIK64165.1 - 0.00028 20.9 0.1 0.00054 20.0 0.1 1.6 1 1 0 1 1 1 1 Central core of the bacterial effector protein AvrPto AvrPto PF11592.8 KIK64167.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 1 1 2 2 2 1 Central core of the bacterial effector protein AvrPto SlyX PF04102.12 KIK64167.1 - 0.045 14.4 1.3 0.063 13.9 0.2 1.8 2 0 0 2 2 2 0 SlyX DUF2207 PF09972.9 KIK64167.1 - 0.047 12.4 0.1 0.068 11.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4315 PF14193.6 KIK64167.1 - 0.085 12.9 0.4 0.15 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Phage_holin_3_6 PF07332.11 KIK64167.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HSBP1 PF06825.12 KIK64167.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 YdaS_antitoxin PF15943.5 KIK64168.1 - 0.0037 17.1 0.0 26 4.8 0.0 4.3 4 0 0 4 4 4 3 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT F-box-like PF12937.7 KIK64170.1 - 2.2e-10 40.3 0.7 6.3e-10 38.8 0.2 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK64170.1 - 7.2e-05 22.6 1.5 0.00023 21.0 0.2 2.6 2 1 0 2 2 2 1 F-box domain F-box-like_2 PF13013.6 KIK64170.1 - 0.1 12.6 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 F-box-like domain zf-MYND PF01753.18 KIK64171.1 - 1.8e-07 31.1 5.3 1.8e-07 31.1 5.3 1.7 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIK64171.1 - 0.002 18.4 1.4 0.0042 17.4 1.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding SlyX PF04102.12 KIK64172.1 - 0.043 14.4 0.2 0.13 12.9 0.2 1.8 1 0 0 1 1 1 0 SlyX EOS1 PF12326.8 KIK64174.1 - 2e-38 132.1 6.8 8.7e-38 130.0 6.8 1.8 1 1 0 1 1 1 1 N-glycosylation protein Peptidase_A4 PF01828.17 KIK64175.1 - 6.8e-58 195.6 11.8 1e-57 195.0 11.8 1.3 1 0 0 1 1 1 1 Peptidase A4 family PD-C2-AF1 PF09310.10 KIK64175.1 - 0.018 14.5 2.2 0.06 12.7 1.4 2.0 1 1 1 2 2 2 0 POU domain, class 2, associating factor 1 TPR_14 PF13428.6 KIK64176.1 - 1.9e-11 43.8 9.7 0.0031 18.2 0.0 7.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK64176.1 - 5.5e-09 35.5 1.9 0.0021 18.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK64176.1 - 8.8e-07 28.6 21.1 0.00088 19.2 0.0 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK64176.1 - 1.1e-06 28.2 5.9 0.0018 18.0 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK64176.1 - 1.7e-06 28.0 4.3 0.1 12.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK64176.1 - 0.00022 21.4 0.2 3.6 7.9 0.0 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KIK64176.1 - 0.003 18.1 1.9 0.08 13.6 0.1 6.1 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KIK64176.1 - 0.0031 16.8 1.9 0.13 11.4 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4810 PF16068.5 KIK64176.1 - 0.026 15.1 0.0 0.098 13.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) TPR_19 PF14559.6 KIK64176.1 - 0.028 14.9 6.4 5.4 7.6 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK64176.1 - 0.17 11.6 8.5 0.78 9.5 0.0 4.8 4 1 1 5 5 5 0 TPR repeat TPR_4 PF07721.14 KIK64176.1 - 0.71 10.7 8.9 1.1e+02 3.9 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK64176.1 - 2.1 8.9 3.4 1.2e+02 3.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Serglycin PF04360.12 KIK64176.1 - 3 7.8 10.9 14 5.6 0.2 3.9 3 0 0 3 3 3 0 Serglycin p450 PF00067.22 KIK64178.1 - 1e-59 202.5 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATG22 PF11700.8 KIK64180.1 - 5.3e-146 487.0 4.0 7.5e-146 486.5 4.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIK64180.1 - 1e-13 51.0 38.2 4.9e-08 32.3 19.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily BNIP3 PF06553.12 KIK64180.1 - 0.16 11.7 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 BNIP3 MMS1_N PF10433.9 KIK64182.1 - 0.061 11.9 0.1 4.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SPC25 PF06703.11 KIK64182.1 - 0.44 10.3 9.0 1.2 8.9 0.7 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Oleosin PF01277.17 KIK64184.1 - 0.097 12.4 0.3 0.097 12.4 0.3 2.8 4 0 0 4 4 4 0 Oleosin DUF1240 PF06836.12 KIK64184.1 - 9.6 6.8 8.5 2.1 8.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) CRIM PF16978.5 KIK64185.1 - 6.1e-45 152.8 0.0 1.8e-44 151.3 0.0 1.9 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KIK64185.1 - 4.4e-29 101.0 0.2 7.3e-29 100.3 0.2 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KIK64185.1 - 8.6e-05 22.7 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KIK64185.1 - 0.0011 19.0 0.0 0.0039 17.2 0.0 2.0 2 0 0 2 2 2 1 Raf-like Ras-binding domain PH PF00169.29 KIK64185.1 - 0.076 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 PH domain TFIIA PF03153.13 KIK64185.1 - 0.89 9.5 5.3 1 9.3 1.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 KIK64188.1 - 7.6e-52 176.6 12.3 1.3e-36 126.5 2.3 2.3 2 1 0 2 2 2 2 ZIP Zinc transporter MBOAT_2 PF13813.6 KIK64190.1 - 5.7e-20 71.4 5.1 8.4e-20 70.8 5.1 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-MYND PF01753.18 KIK64192.1 - 9e-06 25.7 11.1 1.6e-05 24.9 11.1 1.4 1 0 0 1 1 1 1 MYND finger Rad60-SLD PF11976.8 KIK64195.1 - 5.9e-11 42.0 0.1 7.2e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIK64195.1 - 3.1e-05 23.6 0.0 3.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 KIK64195.1 - 0.00024 21.2 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 TUG ubiquitin-like domain DUF4926 PF16277.5 KIK64199.1 - 0.031 13.6 0.0 6.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4926) Ras PF00071.22 KIK64203.1 - 4.6e-57 192.1 0.1 5.5e-57 191.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK64203.1 - 1.9e-33 115.2 0.0 3.4e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK64203.1 - 8.3e-14 51.4 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK64203.1 - 3.8e-07 29.7 0.0 5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK64203.1 - 2.9e-06 27.3 0.0 5.8e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK64203.1 - 0.00018 21.1 0.1 0.00046 19.8 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIK64203.1 - 0.0059 17.0 0.0 0.0094 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KIK64203.1 - 0.0089 15.5 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KIK64203.1 - 0.014 15.1 0.0 0.04 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KIK64203.1 - 0.025 13.8 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 KIK64203.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KIK64203.1 - 0.07 12.3 1.8 1.8 7.6 0.3 2.2 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KIK64203.1 - 0.099 12.5 0.4 0.53 10.2 0.1 2.0 1 1 0 2 2 2 0 RsgA GTPase Mem_trans PF03547.18 KIK64204.1 - 9.1e-14 50.6 9.5 6.6e-13 47.8 9.5 2.0 1 1 0 1 1 1 1 Membrane transport protein Peptidase_M48_N PF16491.5 KIK64206.1 - 7.6e-64 215.0 3.8 7.6e-64 215.0 3.8 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KIK64206.1 - 2e-36 125.6 0.0 3.8e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KIK64206.1 - 0.0041 16.4 0.2 0.0072 15.5 0.2 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 Pkinase PF00069.25 KIK64207.1 - 2.1e-64 217.4 0.0 2.6e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64207.1 - 4.1e-26 91.8 0.0 6.1e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK64207.1 - 5.4e-05 22.7 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK64207.1 - 0.00076 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK64207.1 - 0.00083 19.3 0.1 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK64207.1 - 0.00088 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIK64207.1 - 0.0013 18.3 0.2 0.0025 17.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KIK64207.1 - 0.061 12.9 0.0 0.16 11.5 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Spa1_C PF18218.1 KIK64207.1 - 0.16 12.4 0.0 10 6.6 0.0 2.7 3 0 0 3 3 3 0 Lantibiotic immunity protein Spa1 C-terminal domain Epimerase PF01370.21 KIK64209.1 - 4.6e-07 29.5 0.0 4e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK64209.1 - 6.8e-06 26.1 0.0 9.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK64209.1 - 0.017 14.1 0.0 2.1 7.3 0.0 2.3 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 KIK64209.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 KIK64209.1 - 0.05 13.2 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 KIK64209.1 - 0.092 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KIK64209.1 - 0.18 11.1 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_M43 PF05572.13 KIK64210.1 - 9e-18 64.6 0.1 1.4e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KIK64210.1 - 1.2e-07 32.2 0.1 1.9e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KIK64210.1 - 3.8e-07 30.4 0.6 5e-07 30.1 0.6 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KIK64210.1 - 4e-05 23.4 0.5 6.4e-05 22.7 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KIK64210.1 - 0.024 14.5 0.3 0.033 14.1 0.3 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KIK64210.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 KIK64210.1 - 0.072 12.0 5.0 0.051 12.5 3.3 1.5 1 1 1 2 2 2 0 Peptidase M66 Piwi PF02171.17 KIK64211.1 - 4.2e-79 265.9 0.0 6.3e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK64211.1 - 2.1e-21 77.0 0.0 7e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 KIK64211.1 - 1.9e-15 56.8 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KIK64211.1 - 3.1e-13 49.1 0.8 1.2e-12 47.3 0.6 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIK64211.1 - 1.9e-10 40.9 0.0 7.5e-10 39.0 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK64211.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute P_gingi_FimA PF06321.11 KIK64213.1 - 0.005 17.0 0.3 0.11 12.5 0.0 2.0 2 0 0 2 2 2 1 Major fimbrial subunit protein (FimA) DUF1541 PF07563.11 KIK64213.1 - 0.17 11.8 2.3 19 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) Methyltransf_23 PF13489.6 KIK64215.1 - 4.5e-14 52.6 0.0 6.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK64215.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK64215.1 - 6.3e-12 46.0 0.0 1.5e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK64215.1 - 9e-12 45.6 0.0 1.5e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK64215.1 - 9.6e-12 45.5 0.0 2.3e-11 44.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK64215.1 - 1.5e-07 31.0 0.0 3.3e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK64215.1 - 9.9e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KIK64215.1 - 1.7e-05 24.4 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIK64215.1 - 7.5e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KIK64215.1 - 0.00098 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KIK64215.1 - 0.0088 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 KIK64215.1 - 0.025 13.7 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 DREV methyltransferase MetW PF07021.12 KIK64215.1 - 0.027 14.0 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_7 PF03492.15 KIK64215.1 - 0.034 13.4 0.0 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 SAM dependent carboxyl methyltransferase TRM13 PF05206.14 KIK64215.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 CMAS PF02353.20 KIK64215.1 - 0.095 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short PF00106.25 KIK64216.1 - 3.3e-28 98.5 0.0 8.8e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64216.1 - 3.9e-16 59.3 0.0 8.2e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64216.1 - 5.6e-08 32.9 0.0 1.9e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK64216.1 - 9.1e-05 22.0 0.0 0.00047 19.7 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1601 PF07671.11 KIK64216.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1601) DUF1776 PF08643.10 KIK64216.1 - 0.015 14.6 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KIK64216.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK64217.1 - 2.2e-29 102.3 0.0 1.2e-25 90.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64217.1 - 1e-17 64.5 0.0 1.2e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64217.1 - 7.8e-08 32.4 0.0 2.1e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK64217.1 - 6.1e-05 22.6 0.0 0.00053 19.5 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1601 PF07671.11 KIK64217.1 - 0.053 13.4 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Sacchrp_dh_NADP PF03435.18 KIK64217.1 - 0.079 13.2 0.0 3.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KIK64217.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1242 PF06842.12 KIK64220.1 - 8.8e-19 67.0 1.4 1.3e-18 66.5 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF805 PF05656.14 KIK64220.1 - 0.11 13.0 0.6 0.11 12.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) LST1 PF05083.13 KIK64220.1 - 0.23 11.8 2.3 0.31 11.4 2.0 1.3 1 1 0 1 1 1 0 LST-1 protein NAD_binding_4 PF07993.12 KIK64221.1 - 1.2e-30 106.6 0.0 1.9e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK64221.1 - 8.5e-26 90.5 0.0 1.1e-24 86.8 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIK64221.1 - 4.6e-06 26.3 0.0 8.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK64221.1 - 0.00089 19.6 0.0 0.0026 18.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sulfate_transp PF00916.20 KIK64222.1 - 2.9e-59 200.8 14.1 2.9e-59 200.8 14.1 1.5 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 KIK64222.1 - 1.2e-11 44.5 0.0 2.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KIK64222.1 - 2.3e-09 36.9 0.0 4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KIK64222.1 - 0.011 16.1 2.7 0.011 16.1 2.7 3.3 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Sec62 PF03839.16 KIK64225.1 - 1.8 8.0 7.5 0.83 9.1 5.7 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 KdpC PF02669.15 KIK64226.1 - 0.087 12.7 0.6 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 K+-transporting ATPase, c chain BAR_2 PF10455.9 KIK64227.1 - 6.4e-48 163.4 1.3 1e-47 162.7 1.3 1.2 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KIK64227.1 - 1.1e-17 64.5 1.7 4.7e-15 55.9 0.4 2.0 2 0 0 2 2 2 2 BAR domain NatB_MDM20 PF09797.9 KIK64227.1 - 0.029 13.3 0.7 0.19 10.7 0.1 2.2 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit Phasin PF05597.11 KIK64227.1 - 0.15 12.1 3.3 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4642 PF15484.6 KIK64227.1 - 0.61 10.3 2.7 0.3 11.3 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) DUF4407 PF14362.6 KIK64227.1 - 1.1 8.6 6.2 3 7.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PhyH PF05721.13 KIK64228.1 - 5.4e-11 43.1 0.0 8.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PHP PF02811.19 KIK64229.1 - 5.4e-10 39.8 0.3 6.8e-10 39.5 0.3 1.4 1 1 0 1 1 1 1 PHP domain Rnk_N PF14760.6 KIK64229.1 - 0.0011 19.4 0.3 0.0026 18.2 0.3 1.7 1 0 0 1 1 1 1 Rnk N-terminus Sugarporin_N PF11471.8 KIK64230.1 - 0.0023 17.9 0.9 0.7 9.9 0.0 2.2 2 0 0 2 2 2 2 Maltoporin periplasmic N-terminal extension Helo_like_N PF17111.5 KIK64230.1 - 0.0034 16.8 0.6 0.049 13.0 0.1 2.0 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins MtrG PF04210.13 KIK64230.1 - 0.0043 16.9 0.9 2.2 8.2 0.2 2.2 2 0 0 2 2 2 2 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3583 PF12126.8 KIK64230.1 - 0.012 15.1 0.1 0.013 14.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DASH_Dad3 PF08656.10 KIK64230.1 - 0.016 15.2 0.0 4 7.6 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2730 PF10805.8 KIK64230.1 - 0.017 15.2 0.7 0.14 12.3 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) BRI3BP PF14965.6 KIK64230.1 - 0.017 14.6 0.6 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Vac_Fusion PF02346.16 KIK64230.1 - 0.04 13.6 1.1 6.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF5314 PF17241.2 KIK64230.1 - 0.087 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5314) GTP-bdg_M PF16360.5 KIK64230.1 - 0.14 12.8 2.8 4.1 8.1 2.1 2.2 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region HTH_10 PF04967.12 KIK64230.1 - 0.16 11.8 0.6 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain EMP24_GP25L PF01105.24 KIK64230.1 - 2.9 7.8 6.4 35 4.3 6.4 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PHP PF02811.19 KIK64233.1 - 1.9e-09 38.1 0.0 1.9e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 PHP domain Rnk_N PF14760.6 KIK64233.1 - 0.044 14.3 0.2 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 Rnk N-terminus DASH_Dad3 PF08656.10 KIK64234.1 - 0.094 12.8 0.4 0.25 11.4 0.4 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad3 Peptidase_M24 PF00557.24 KIK64237.1 - 2.3e-46 158.1 0.0 2.8e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldo_ket_red PF00248.21 KIK64240.1 - 1.9e-73 247.2 0.0 2.2e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK64241.1 - 2.3e-70 237.1 0.0 2.6e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_3 PF07859.13 KIK64242.1 - 3e-13 50.1 0.0 4.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK64242.1 - 1.6e-08 33.9 0.1 1.2e-07 31.0 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK64242.1 - 2.9e-06 26.9 0.0 3.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIK64242.1 - 0.091 12.3 0.2 0.21 11.1 0.2 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KIK64243.1 - 5e-16 59.2 0.0 7.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK64243.1 - 2.4e-08 33.3 1.2 1.8e-07 30.4 1.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KIK64243.1 - 3.2e-05 23.0 0.0 4.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK64243.1 - 0.00011 21.4 0.1 0.00015 20.9 0.1 1.1 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.21 KIK64243.1 - 0.0002 20.9 0.0 0.00073 19.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family adh_short PF00106.25 KIK64244.1 - 2.3e-13 50.1 0.0 1e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64244.1 - 0.00016 21.3 0.0 0.00037 20.1 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64244.1 - 0.012 15.5 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 KR domain AMP-binding PF00501.28 KIK64245.1 - 2.5e-95 319.6 0.0 3.1e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK64245.1 - 2.5e-23 82.9 0.1 7.3e-23 81.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KIK64245.1 - 8.7e-12 44.8 0.2 5.7e-11 42.2 0.4 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KIK64245.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Malectin_like PF12819.7 KIK64245.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Malectin-like domain EKR PF10371.9 KIK64245.1 - 0.096 12.5 0.3 3 7.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function Abhydrolase_3 PF07859.13 KIK64248.1 - 5.6e-15 55.8 0.0 8.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK64248.1 - 1.8e-07 30.5 0.7 1.7e-06 27.2 0.6 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK64248.1 - 0.00018 21.1 0.0 0.0012 18.4 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KIK64248.1 - 0.00047 19.2 0.0 0.00069 18.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK64248.1 - 0.00074 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PSI_8 PF00796.18 KIK64248.1 - 0.15 11.9 5.0 0.29 11.0 5.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Hydrolase_4 PF12146.8 KIK64248.1 - 0.22 10.7 0.0 0.79 8.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIK64249.1 - 9.7e-14 51.7 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK64249.1 - 9.7e-10 37.9 0.1 8.5e-09 34.8 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK64249.1 - 0.0002 20.9 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KIK64249.1 - 0.00027 20.0 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK64249.1 - 0.00084 18.4 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KIK64249.1 - 0.034 13.4 0.0 0.13 11.5 0.0 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 KIK64251.1 - 1.8e-23 83.2 0.0 2.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64251.1 - 1.4e-21 77.0 0.0 2.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 KIK64251.1 - 2.3e-14 53.6 3.6 1.3e-05 25.6 0.2 7.1 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK64251.1 - 3e-14 53.4 0.2 1.1e-06 29.1 0.1 5.8 5 2 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK64251.1 - 3e-10 39.4 13.9 1.4 9.7 0.0 8.7 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 KIK64251.1 - 0.0001 22.5 6.4 0.72 10.3 0.1 5.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK64251.1 - 0.034 14.6 13.6 27 5.4 0.1 7.3 9 0 0 9 9 9 0 Ankyrin repeat Lipase_GDSL_2 PF13472.6 KIK64252.1 - 2e-06 28.3 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1412 PF07203.11 KIK64252.1 - 0.39 10.9 3.0 0.59 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) RhoGEF PF00621.20 KIK64253.1 - 0.047 13.9 0.0 0.047 13.9 0.0 1.0 1 0 0 1 1 1 0 RhoGEF domain TcdB_N PF12918.7 KIK64254.1 - 0.082 13.2 1.8 0.37 11.1 0.3 2.2 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Aldo_ket_red PF00248.21 KIK64255.1 - 5.5e-74 249.0 0.0 6.2e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TMEM173 PF15009.6 KIK64257.1 - 0.59 9.2 2.8 0.76 8.9 1.3 1.9 2 0 0 2 2 2 0 Transmembrane protein 173 Nuf2 PF03800.14 KIK64258.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nuf2 family Peptidase_M36 PF02128.15 KIK64261.1 - 2.3e-160 533.8 0.7 3e-160 533.4 0.7 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIK64261.1 - 4.7e-15 55.1 0.8 1.5e-14 53.6 0.8 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif ABC_tran PF00005.27 KIK64262.1 - 1.2e-25 90.7 0.1 6e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KIK64262.1 - 2.6e-06 27.5 0.0 0.00012 22.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK64262.1 - 2.6e-06 27.4 0.0 8.3e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KIK64262.1 - 4.9e-06 26.1 0.2 0.035 13.5 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KIK64262.1 - 0.00018 20.9 0.0 0.00038 19.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 KIK64262.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 KIK64262.1 - 0.00088 19.8 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK64262.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIK64262.1 - 0.0016 18.7 0.1 0.0048 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIK64262.1 - 0.0019 18.2 0.0 0.0075 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIK64262.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK64262.1 - 0.0049 17.0 0.0 0.0094 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK64262.1 - 0.0057 17.1 0.1 0.014 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK64262.1 - 0.0083 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KIK64262.1 - 0.01 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KIK64262.1 - 0.019 13.8 0.1 0.43 9.3 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 KIK64262.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIK64262.1 - 0.035 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 KIK64262.1 - 0.052 13.4 0.2 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.12 KIK64262.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KIK64262.1 - 0.095 13.3 0.0 0.41 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KIK64262.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_27 PF13514.6 KIK64262.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK64262.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 KIK64262.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KIK64262.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNARE_assoc PF09335.11 KIK64263.1 - 7.9e-12 45.7 6.5 7.9e-12 45.7 6.5 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein COX4 PF02936.14 KIK64263.1 - 0.043 13.8 0.4 20 5.2 0.1 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Phage_holin_3_6 PF07332.11 KIK64263.1 - 0.054 13.5 0.0 0.054 13.5 0.0 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM154 PF15102.6 KIK64263.1 - 0.18 11.7 0.1 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF4199 PF13858.6 KIK64263.1 - 2.8 8.3 16.8 15 6.0 0.7 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2274 PF10038.9 KIK64264.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) SNARE_assoc PF09335.11 KIK64265.1 - 4.3e-12 46.6 5.5 4.3e-12 46.6 5.5 2.1 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4271 PF14093.6 KIK64265.1 - 4.3 7.2 11.1 2.2 8.2 0.8 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4271) DUF5510 PF17629.2 KIK64265.1 - 9.6 6.2 9.1 0.32 11.0 0.6 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5510) DUF3522 PF12036.8 KIK64266.1 - 0.076 13.3 1.3 0.14 12.4 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) DUF3487 PF11990.8 KIK64266.1 - 0.13 12.2 0.8 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) SNARE_assoc PF09335.11 KIK64267.1 - 7.4e-16 58.7 7.1 7.4e-16 58.7 7.1 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein NYN PF01936.18 KIK64268.1 - 2.1e-21 76.9 0.0 3.9e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 NYN domain REPA_OB_2 PF16900.5 KIK64268.1 - 0.11 12.5 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Replication protein A OB domain NYN PF01936.18 KIK64269.1 - 2.1e-22 80.2 0.0 4e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 NYN domain Glyco_hydro_28 PF00295.17 KIK64270.1 - 1.2e-38 133.0 4.3 1.6e-38 132.6 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIK64270.1 - 0.0037 17.1 6.5 0.0037 17.1 6.5 1.8 2 0 0 2 2 2 1 Right handed beta helix region FixQ PF05545.11 KIK64271.1 - 0.1 12.6 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ HA2 PF04408.23 KIK64273.1 - 4.8e-23 81.5 0.0 8.9e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK64273.1 - 6e-11 42.7 0.0 2.2e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TMEM173 PF15009.6 KIK64274.1 - 0.46 9.6 3.2 0.78 8.8 2.3 1.8 2 0 0 2 2 2 0 Transmembrane protein 173 Colicin_im PF03857.13 KIK64275.1 - 0.18 11.8 4.2 0.1 12.6 1.3 2.0 2 0 0 2 2 2 0 Colicin immunity protein OB_NTP_bind PF07717.16 KIK64276.1 - 1.5e-18 67.0 0.0 1.9e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Plasmid_stab_B PF10784.9 KIK64276.1 - 0.2 11.5 0.2 0.76 9.7 0.1 1.9 1 1 1 2 2 2 0 Plasmid stability protein DUF1633 PF07794.11 KIK64277.1 - 0.13 10.4 0.5 0.18 9.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DUF4044 PF13253.6 KIK64277.1 - 6.2 6.4 6.0 3 7.4 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Pkinase_fungal PF17667.1 KIK64279.1 - 4.1e-23 81.8 0.0 1.2e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIK64282.1 - 9.7e-10 37.8 0.0 1.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Acyltransferase PF01553.21 KIK64283.1 - 5.4e-17 61.7 0.0 1.8e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Flu_B_M2 PF04772.12 KIK64284.1 - 0.062 13.5 0.7 0.11 12.8 0.1 1.6 2 0 0 2 2 2 0 Influenza B matrix protein 2 (BM2) C1-set PF07654.15 KIK64284.1 - 0.7 10.3 3.5 3 8.3 1.4 2.6 2 1 1 3 3 3 0 Immunoglobulin C1-set domain GREB1 PF15782.5 KIK64284.1 - 1.4 6.0 11.3 1.5 5.8 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 KIK64284.1 - 2.9 7.1 11.6 4.3 6.6 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_4 PF07993.12 KIK64285.1 - 2.5e-25 89.1 0.0 4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK64285.1 - 3.4e-22 78.6 0.0 8.1e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 KIK64285.1 - 0.00032 21.0 0.0 0.00083 19.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIK64285.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KIK64286.1 - 3e-27 95.5 22.2 9.1e-23 80.7 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtC PF02308.16 KIK64286.1 - 3.9 7.9 8.8 0.7 10.3 3.1 2.7 2 2 0 2 2 2 0 MgtC family MFS_1 PF07690.16 KIK64287.1 - 1.2e-31 110.0 23.5 1.2e-31 110.0 23.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK64287.1 - 0.032 13.5 19.7 0.0074 15.6 6.9 2.4 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB ESSS PF10183.9 KIK64287.1 - 0.16 12.2 1.1 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MgtE PF01769.16 KIK64288.1 - 4.7e-45 153.0 20.8 4.1e-24 85.3 9.9 3.2 2 1 1 3 3 3 2 Divalent cation transporter PEMT PF04191.13 KIK64289.1 - 6.4e-05 23.3 1.5 0.00011 22.6 0.3 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIK64289.1 - 0.002 17.7 0.2 0.0043 16.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK64289.1 - 0.011 16.1 0.1 0.02 15.3 0.1 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family AA_permease PF00324.21 KIK64294.1 - 1.8e-112 376.4 39.5 2.3e-112 376.1 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK64294.1 - 3.2e-36 125.1 41.3 4.4e-36 124.6 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease PEMT PF04191.13 KIK64295.1 - 6e-11 42.7 0.1 3.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KIK64295.1 - 2.5e-06 27.8 0.2 6.4e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KIK64295.1 - 0.0059 15.4 0.2 0.016 14.0 0.1 1.8 2 1 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KIK64296.1 - 2.6e-10 40.7 0.6 3.3e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KIK64296.1 - 2.7e-06 27.7 0.1 5.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK64297.1 - 1.5e-09 38.2 0.2 3.1e-09 37.2 0.1 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KIK64297.1 - 6.3e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KIK64297.1 - 0.0026 16.6 0.2 0.0053 15.6 0.2 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NMO PF03060.15 KIK64298.1 - 4.1e-50 171.1 0.5 5.8e-50 170.5 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK64298.1 - 2.9e-11 43.0 0.2 4.7e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK64298.1 - 0.006 15.7 1.6 0.01 14.9 1.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase RNA_polI_A34 PF08208.11 KIK64300.1 - 8.5e-25 88.1 29.2 8.5e-25 88.1 29.2 2.7 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Eapp_C PF10238.9 KIK64300.1 - 0.51 10.4 7.5 14 5.7 0.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein DAG_kinase_N PF14513.6 KIK64300.1 - 6.5 6.9 10.8 0.96 9.6 4.2 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus F-box-like PF12937.7 KIK64301.1 - 0.0003 20.6 2.3 0.00037 20.3 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK64302.1 - 3.5e-06 26.8 2.0 3.8e-06 26.7 0.4 2.0 2 0 0 2 2 2 1 F-box-like DUF3455 PF11937.8 KIK64303.1 - 2.2e-25 89.9 0.0 3.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Retrotran_gag_2 PF14223.6 KIK64306.1 - 3.5e-11 42.9 0.0 3.7e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Mak10 PF04112.13 KIK64309.1 - 2.9e-47 160.3 0.0 6.1e-47 159.2 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cellulase PF00150.18 KIK64310.1 - 5.7e-31 108.0 3.8 9.2e-31 107.3 3.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.7 KIK64311.1 - 6.9e-09 35.5 1.3 1.7e-08 34.2 0.7 2.1 2 0 0 2 2 2 1 F-box-like Cyclin_N PF00134.23 KIK64314.1 - 2.7e-05 23.9 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK64314.1 - 0.0033 17.8 1.0 0.0043 17.4 1.0 1.3 1 1 0 1 1 1 1 Cyclin TPR_10 PF13374.6 KIK64315.1 - 5.5e-65 213.7 2.5 2.1e-09 37.0 0.0 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK64315.1 - 7.6e-45 151.1 16.6 4e-12 46.2 0.0 6.1 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK64315.1 - 2.7e-13 50.0 9.1 6e-05 22.6 0.8 3.5 1 1 3 4 4 4 3 MalT-like TPR region TPR_8 PF13181.6 KIK64315.1 - 1.5e-10 40.5 10.9 0.014 15.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK64315.1 - 3.5e-09 36.0 10.8 0.012 15.6 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK64315.1 - 2.4e-06 27.5 2.7 24 5.6 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK64315.1 - 5.4e-06 26.8 4.5 0.017 15.6 0.5 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK64315.1 - 1.7e-05 24.6 13.1 0.058 13.5 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK64315.1 - 0.00013 22.5 0.2 3 8.6 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK64315.1 - 0.0013 19.1 0.0 7.8 7.4 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK64315.1 - 0.018 15.8 0.5 2e+02 3.2 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK64315.1 - 0.019 14.8 12.7 0.45 10.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4919 PF16266.5 KIK64315.1 - 0.026 14.5 2.8 7.5 6.5 0.1 4.2 2 2 4 6 6 6 0 Domain of unknown function (DUF4919) PPR PF01535.20 KIK64315.1 - 0.15 12.3 5.3 39 4.8 0.0 5.2 5 1 0 5 5 5 0 PPR repeat 3HCDH_N PF02737.18 KIK64316.1 - 5.6e-22 78.5 1.8 4.6e-14 52.7 1.5 3.1 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIK64316.1 - 3.5e-14 53.2 0.7 4.1e-05 24.1 0.0 3.3 2 1 1 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_RFF PF18321.1 KIK64316.1 - 0.057 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain FAD_binding_3 PF01494.19 KIK64317.1 - 4.4e-10 39.3 0.0 7e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK64317.1 - 0.00061 20.0 0.6 0.0019 18.4 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK64317.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TPR_10 PF13374.6 KIK64318.1 - 2.4e-55 183.0 4.9 6.1e-09 35.5 0.2 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK64318.1 - 6.1e-43 145.0 21.3 1.3e-10 41.4 0.2 5.3 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK64318.1 - 3.1e-13 49.8 8.4 5.3e-09 35.9 3.4 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KIK64318.1 - 8.7e-10 38.0 6.3 0.64 10.4 0.3 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK64318.1 - 1.3e-07 31.1 7.5 0.45 10.7 0.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK64318.1 - 3.3e-06 27.1 2.8 2.8 8.5 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK64318.1 - 6.1e-05 23.4 3.7 0.16 12.5 0.2 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK64318.1 - 0.00031 21.1 0.6 10 7.1 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK64318.1 - 0.0049 16.9 10.4 8.4 6.8 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK64318.1 - 1.1 9.1 8.4 21 5.1 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK64318.1 - 5.3 8.1 6.8 35 5.6 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.7 KIK64319.1 - 1.3e-05 25.0 0.3 4.5e-05 23.3 0.3 2.0 1 1 0 1 1 1 1 F-box-like IF-2B PF01008.17 KIK64319.1 - 0.073 12.3 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Initiation factor 2 subunit family F-box-like PF12937.7 KIK64320.1 - 0.0011 18.8 0.4 0.0041 17.0 0.2 2.1 2 1 0 2 2 2 1 F-box-like DUF4646 PF15496.6 KIK64320.1 - 0.17 12.5 0.1 3.9 8.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4646) FeThRed_A PF02941.15 KIK64320.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain Acetyltransf_1 PF00583.25 KIK64321.1 - 9e-08 32.4 0.1 1.3e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK64321.1 - 2.7e-06 27.7 0.1 6.7e-06 26.5 0.0 1.6 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK64321.1 - 3.8e-05 23.6 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK64321.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIK64321.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK64321.1 - 0.078 13.0 0.4 0.16 12.0 0.4 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.7 KIK64322.1 - 4.9e-05 23.1 1.7 0.00016 21.5 1.7 2.0 1 0 0 1 1 1 1 F-box-like DUF5570 PF17731.1 KIK64323.1 - 0.019 15.1 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5570) F5_F8_type_C PF00754.25 KIK64324.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain FdtA PF05523.11 KIK64325.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal SDA1 PF05285.12 KIK64328.1 - 7.8 5.8 15.7 8.4 5.7 15.7 1.1 1 0 0 1 1 1 0 SDA1 Carm_PH PF17888.1 KIK64329.1 - 0.08 13.3 0.1 9.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Carmil pleckstrin homology domain Lactonase PF10282.9 KIK64331.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KIK64331.1 - 0.0032 16.1 0.5 0.35 9.4 0.0 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain MFS_1 PF07690.16 KIK64332.1 - 1.3e-25 90.1 25.8 1.3e-25 90.1 25.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK64332.1 - 1.2e-08 34.2 1.2 1.2e-08 34.2 1.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 KIK64333.1 - 3e-10 39.4 0.2 5e-09 35.4 0.2 2.2 1 1 0 1 1 1 1 Cytochrome P450 TFB6 PF17110.5 KIK64334.1 - 0.00053 19.8 0.1 0.0029 17.4 0.0 2.2 1 1 2 3 3 3 1 Subunit 11 of the general transcription factor TFIIH NACHT PF05729.12 KIK64340.1 - 1e-06 28.8 0.5 4.4e-06 26.7 0.5 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK64340.1 - 1.2e-05 25.8 0.0 0.00011 22.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 KIK64340.1 - 0.0038 17.2 0.6 0.021 14.7 0.1 2.5 2 1 0 2 2 2 1 NTPase AAA_18 PF13238.6 KIK64340.1 - 0.015 15.9 0.1 0.59 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK64340.1 - 0.018 15.4 0.9 0.09 13.2 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK64340.1 - 0.02 14.8 0.3 0.039 13.9 0.3 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK64340.1 - 0.029 13.6 0.0 0.082 12.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIK64340.1 - 0.029 14.7 1.3 0.11 12.9 0.1 2.5 2 1 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KIK64340.1 - 0.031 14.6 0.1 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIK64340.1 - 0.053 13.7 1.4 0.08 13.1 0.3 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK64340.1 - 0.056 13.3 0.3 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea XRN_M PF17846.1 KIK64340.1 - 0.2 10.6 1.0 0.28 10.1 1.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF87 PF01935.17 KIK64340.1 - 0.45 10.6 4.6 4.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KIK64340.1 - 2.7 8.5 7.9 19 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KIK64341.1 - 2.2e-131 423.9 74.3 5.1e-10 39.8 0.5 15.1 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64341.1 - 9e-49 163.7 2.6 0.012 15.9 0.0 13.9 2 2 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64341.1 - 1.4e-25 90.0 16.5 0.13 11.1 0.0 13.3 2 2 12 14 14 14 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK64341.1 - 1.8e-20 72.3 18.6 2.4 8.2 0.0 13.8 14 0 0 14 14 14 8 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK64341.1 - 2.1e-11 44.1 14.3 0.0041 16.9 0.2 7.2 2 2 4 7 7 7 3 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK64341.1 - 1.6e-10 40.8 0.3 4.1 6.6 0.0 9.0 6 4 3 11 11 11 2 WD40-like domain Frtz PF11768.8 KIK64341.1 - 6.9e-10 37.9 0.0 1.4 7.2 0.0 7.9 4 2 6 10 10 10 3 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK64341.1 - 0.00047 18.9 21.1 2.5 6.6 0.3 9.3 7 5 4 12 12 12 3 Nucleoporin Nup120/160 PQQ PF01011.21 KIK64341.1 - 0.0012 18.7 0.2 81 3.4 0.0 7.0 9 0 0 9 9 9 0 PQQ enzyme repeat WD40_3 PF15911.5 KIK64341.1 - 0.046 13.7 8.5 87 3.2 0.0 8.2 11 0 0 11 11 10 0 WD domain, G-beta repeat BAT PF15915.5 KIK64341.1 - 0.056 13.3 5.7 13 5.6 0.1 5.3 5 1 1 6 6 6 0 GAF and HTH_10 associated domain DUF3313 PF11769.8 KIK64341.1 - 0.28 11.0 0.9 18 5.1 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3313) rOmpB PF12334.8 KIK64341.1 - 0.43 10.0 25.5 22 4.4 0.1 10.0 7 4 5 13 13 13 0 Rickettsia outer membrane protein B Nucleoporin_N PF08801.11 KIK64341.1 - 0.73 8.5 4.2 9 4.9 0.0 3.9 3 3 0 4 4 4 0 Nup133 N terminal like F-box-like PF12937.7 KIK64345.1 - 0.0049 16.7 0.3 0.014 15.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK64346.1 - 0.0063 16.4 0.8 0.0063 16.4 0.8 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK64347.1 - 0.05 13.5 2.3 0.81 9.6 2.3 2.6 1 1 0 1 1 1 0 F-box-like CFEM PF05730.11 KIK64348.1 - 0.045 13.8 4.1 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 CFEM domain PAF-AH_p_II PF03403.13 KIK64349.1 - 1.3e-19 70.0 0.0 6.4e-14 51.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIK64349.1 - 3.3e-06 26.2 0.0 8.2e-06 24.9 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIK64349.1 - 0.0022 17.3 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK64349.1 - 0.0023 17.6 0.1 0.0085 15.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KIK64349.1 - 0.0072 15.4 0.5 0.063 12.3 0.1 2.2 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 KIK64349.1 - 0.013 16.2 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KIK64349.1 - 0.053 13.3 0.0 4.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.7 KIK64350.1 - 0.00068 19.5 0.2 0.0022 17.9 0.2 2.0 1 0 0 1 1 1 1 F-box-like Siah-Interact_N PF09032.11 KIK64350.1 - 0.029 14.7 0.2 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF4428 PF14471.6 KIK64350.1 - 0.14 12.1 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) F-box-like PF12937.7 KIK64351.1 - 0.02 14.8 0.6 0.087 12.7 0.6 2.1 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KIK64351.1 - 0.021 15.3 4.6 30 5.2 0.0 4.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Transp_cyt_pur PF02133.15 KIK64352.1 - 5.3e-94 315.5 35.3 6.7e-94 315.2 35.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_holin_Dp1 PF16938.5 KIK64352.1 - 5.1 7.4 8.8 6 7.2 0.1 3.7 3 1 0 3 3 3 0 Putative phage holin Dp-1 MFS_1 PF07690.16 KIK64354.1 - 3.4e-25 88.7 55.0 2.5e-16 59.6 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KIK64354.1 - 5.1 7.4 11.2 4.9 7.5 2.3 3.3 2 0 0 2 2 2 0 Transglycosylase associated protein adh_short PF00106.25 KIK64355.1 - 1.3e-16 60.6 0.3 1.5e-16 60.5 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64355.1 - 1.2e-07 31.5 0.1 1.4e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64355.1 - 1.5e-06 28.3 0.1 1.8e-06 28.0 0.1 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK64355.1 - 0.022 14.2 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK64355.1 - 0.073 12.4 0.0 0.082 12.3 0.0 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase dNK PF01712.19 KIK64355.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase MFS_1 PF07690.16 KIK64357.1 - 1.4e-27 96.6 53.4 5.9e-19 68.2 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIK64359.1 - 1.5e-05 24.8 0.3 2.9e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like Metal_resist PF13801.6 KIK64359.1 - 0.078 13.2 2.3 0.17 12.1 2.3 1.5 1 0 0 1 1 1 0 Heavy-metal resistance PRKG1_interact PF15898.5 KIK64359.1 - 0.09 13.7 0.9 0.18 12.8 0.9 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain PSCyt3 PF07627.11 KIK64359.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-C2H2_jaz PF12171.8 KIK64360.1 - 5.8e-12 45.6 16.6 0.00016 21.9 0.7 4.3 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C3HC4_3 PF13920.6 KIK64360.1 - 8.8e-09 35.1 10.8 8.8e-09 35.1 10.8 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK64360.1 - 1.5e-07 31.2 13.2 1.5e-07 31.2 13.2 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK64360.1 - 3.4e-07 30.5 13.2 3.4e-07 30.5 13.2 3.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK64360.1 - 4.5e-07 29.6 13.5 4.5e-07 29.6 13.5 3.4 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 KIK64360.1 - 6.8e-07 29.5 8.3 0.00032 21.0 0.4 4.6 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-RING_5 PF14634.6 KIK64360.1 - 3.9e-06 26.7 14.3 3.9e-06 26.7 14.3 3.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C2H2_4 PF13894.6 KIK64360.1 - 0.0001 22.8 4.7 0.017 15.9 0.4 5.4 5 1 0 5 5 4 3 C2H2-type zinc finger Prok-RING_4 PF14447.6 KIK64360.1 - 0.00019 21.2 12.9 0.00019 21.2 12.9 3.6 3 2 2 5 5 5 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KIK64360.1 - 0.0012 19.1 10.5 0.0012 19.1 10.5 2.7 3 2 1 4 4 4 1 RING-H2 zinc finger domain zf-C2H2 PF00096.26 KIK64360.1 - 0.0014 19.0 7.1 0.012 16.0 0.8 4.9 5 1 0 5 5 4 3 Zinc finger, C2H2 type zf-RING_UBOX PF13445.6 KIK64360.1 - 0.0021 18.0 12.8 0.0021 18.0 12.8 3.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.6 KIK64360.1 - 0.0052 16.6 8.7 0.0052 16.6 8.7 2.5 3 1 1 4 4 3 1 zf-RING of BARD1-type protein NADH-G_4Fe-4S_3 PF10588.9 KIK64360.1 - 0.012 15.1 0.8 0.012 15.1 0.8 4.1 4 1 0 4 4 4 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region FYVE PF01363.21 KIK64360.1 - 0.067 13.3 21.2 0.078 13.1 5.4 3.4 1 1 2 3 3 3 0 FYVE zinc finger Zn-C2H2_12 PF18112.1 KIK64360.1 - 0.38 11.3 0.1 0.38 11.3 0.1 4.6 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KIK64360.1 - 0.41 11.0 18.6 0.58 10.5 0.4 4.3 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-RING_13 PF17977.1 KIK64360.1 - 5.8 7.1 13.2 16 5.7 4.2 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C2H2_6 PF13912.6 KIK64360.1 - 6.1 7.0 21.5 0.44 10.6 0.8 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-RING_4 PF14570.6 KIK64360.1 - 7.5 6.4 21.2 0.82 9.5 11.0 3.7 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 KIK64361.1 - 2.2e-31 108.9 0.0 5.2e-28 97.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64361.1 - 1.6e-17 63.9 0.0 3e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64361.1 - 1.8e-09 37.8 0.0 3.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK64361.1 - 6.9e-05 22.4 0.0 0.00014 21.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK64361.1 - 0.0077 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1340 PF07067.11 KIK64361.1 - 0.074 12.4 0.0 0.59 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1340) Thi4 PF01946.17 KIK64362.1 - 0.047 12.9 0.1 0.048 12.9 0.1 1.0 1 0 0 1 1 1 0 Thi4 family CdhC PF03598.15 KIK64363.1 - 0.047 13.5 8.3 0.44 10.4 0.1 3.3 3 0 0 3 3 3 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit PorB PF11565.8 KIK64363.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Alpha helical Porin B UCH_C PF18031.1 KIK64363.1 - 0.85 9.6 25.4 0.68 9.9 2.1 3.5 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolases zf-C2H2_jaz PF12171.8 KIK64365.1 - 2.9e-12 46.5 16.2 0.00017 21.8 0.7 4.2 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C3HC4_3 PF13920.6 KIK64365.1 - 2.2e-07 30.6 13.9 2.2e-07 30.6 13.9 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 KIK64365.1 - 5.4e-07 29.8 23.2 0.00034 20.9 0.4 4.6 5 0 0 5 5 3 3 Zinc-finger of C2H2 type zf-C3HC4 PF00097.25 KIK64365.1 - 2.2e-06 27.4 16.0 2.2e-06 27.4 16.0 3.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK64365.1 - 5.4e-06 26.1 16.6 5.4e-06 26.1 16.6 3.3 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK64365.1 - 6.7e-06 26.3 16.3 6.7e-06 26.3 16.3 3.2 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KIK64365.1 - 7.8e-06 25.8 17.4 7.8e-06 25.8 17.4 3.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C2H2_4 PF13894.6 KIK64365.1 - 3e-05 24.5 9.9 0.018 15.8 0.4 5.4 5 1 0 5 5 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK64365.1 - 0.0006 20.1 5.7 0.013 15.9 0.8 5.0 5 1 0 5 5 4 3 Zinc finger, C2H2 type Prok-RING_4 PF14447.6 KIK64365.1 - 0.0031 17.3 15.5 0.0031 17.3 15.5 3.5 3 2 2 5 5 5 1 Prokaryotic RING finger family 4 NADH-G_4Fe-4S_3 PF10588.9 KIK64365.1 - 0.011 15.2 0.6 0.011 15.2 0.6 4.2 6 0 0 6 6 5 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-RING_UBOX PF13445.6 KIK64365.1 - 0.011 15.7 14.6 0.011 15.7 14.6 2.9 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_6 PF14835.6 KIK64365.1 - 0.011 15.5 11.1 0.011 15.5 11.1 2.4 3 1 0 3 3 2 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.6 KIK64365.1 - 0.029 14.4 0.8 0.029 14.4 0.8 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KIK64365.1 - 0.41 11.2 0.1 0.41 11.2 0.1 4.4 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 KIK64365.1 - 0.52 10.7 17.4 0.59 10.5 0.4 4.2 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-rbx1 PF12678.7 KIK64365.1 - 4 7.8 22.2 0.067 13.5 13.1 2.8 3 1 0 3 3 3 0 RING-H2 zinc finger domain FYVE PF01363.21 KIK64365.1 - 5.8 7.1 25.9 0.64 10.2 7.7 3.4 1 1 2 3 3 3 0 FYVE zinc finger F-box-like PF12937.7 KIK64366.1 - 0.00045 20.0 0.4 0.0011 18.8 0.4 1.8 1 0 0 1 1 1 1 F-box-like DUF1351 PF07083.11 KIK64366.1 - 0.14 11.9 0.3 0.25 11.1 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) S8_pro-domain PF16470.5 KIK64367.1 - 0.082 13.7 0.1 0.13 13.0 0.1 1.3 1 1 0 1 1 1 0 Peptidase S8 pro-domain C2 PF00168.30 KIK64369.1 - 1.7e-14 53.9 0.1 2.9e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 C2 domain YscO-like PF16789.5 KIK64369.1 - 0.88 9.6 6.4 0.45 10.5 0.3 2.2 2 0 0 2 2 2 0 YscO-like protein Aldo_ket_red PF00248.21 KIK64370.1 - 3.5e-33 115.1 0.0 6.5e-33 114.2 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family adh_short PF00106.25 KIK64371.1 - 6.9e-12 45.2 0.0 9.3e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64371.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64371.1 - 1.9e-06 27.9 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK64371.1 - 0.00071 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KIK64372.1 - 7.5e-12 45.1 0.1 1.3e-11 44.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64372.1 - 2.4e-09 37.1 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64372.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK64372.1 - 0.0051 17.1 0.0 0.0096 16.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ABC_tran PF00005.27 KIK64374.1 - 1.4e-20 74.2 0.0 3.6e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 KIK64374.1 - 2.3e-07 30.9 0.0 6.6e-06 26.1 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KIK64374.1 - 4.8e-07 29.9 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK64374.1 - 4e-05 23.2 0.0 0.054 12.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK64374.1 - 0.00023 21.6 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KIK64374.1 - 0.00031 20.5 0.0 0.002 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIK64374.1 - 0.00035 21.1 0.1 0.0012 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK64374.1 - 0.00046 19.9 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK64374.1 - 0.0029 17.9 0.0 0.0094 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain MTS_N PF08468.11 KIK64374.1 - 0.003 17.7 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain N-terminal Zeta_toxin PF06414.12 KIK64374.1 - 0.0086 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 KIK64374.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KIK64374.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KIK64374.1 - 0.049 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK64374.1 - 0.05 13.6 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK64374.1 - 0.055 13.2 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KIK64374.1 - 0.078 12.7 0.1 0.51 10.0 0.0 2.4 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 KIK64374.1 - 0.088 12.0 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KIK64374.1 - 0.09 12.5 0.1 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KIK64374.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 KIK64374.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KIK64374.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 KIK64374.1 - 0.15 12.6 0.0 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK64374.1 - 0.17 11.9 0.1 0.32 11.1 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KIK64374.1 - 0.2 11.7 0.6 0.49 10.4 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Glyco_hydro_30 PF02055.16 KIK64378.1 - 9.1e-25 87.4 0.1 1.2e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIK64378.1 - 4.6e-14 52.3 0.0 7.8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KIK64378.1 - 0.00094 18.9 0.0 0.013 15.1 0.0 2.1 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 PSA_CBD PF18341.1 KIK64382.1 - 0.12 12.4 0.6 0.37 10.9 0.5 1.9 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain Acyltransferase PF01553.21 KIK64382.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase MFS_1 PF07690.16 KIK64384.1 - 9.5e-38 130.0 36.5 1.8e-37 129.1 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tim17 PF02466.19 KIK64385.1 - 0.16 12.3 6.4 0.21 12.0 6.4 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family FTR1 PF03239.14 KIK64387.1 - 0.012 14.8 0.2 0.017 14.3 0.2 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family POTRA_2 PF08479.11 KIK64387.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type TPMT PF05724.11 KIK64388.1 - 1.7e-37 129.2 0.0 2e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KIK64388.1 - 3.6e-11 43.6 0.0 4.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK64388.1 - 7.9e-09 35.5 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK64388.1 - 7.3e-08 33.0 0.0 1e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK64388.1 - 1.8e-07 31.8 0.0 2.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK64388.1 - 7.1e-05 22.7 0.0 9.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIK64388.1 - 0.00034 20.1 0.0 0.00041 19.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 KIK64388.1 - 0.016 14.7 0.0 0.09 12.3 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 KIK64388.1 - 0.029 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KIK64388.1 - 0.078 12.4 0.7 1 8.7 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KIK64388.1 - 0.085 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KIK64388.1 - 0.22 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 KIK64390.1 - 3.4e-08 33.5 0.0 9.5e-07 28.8 0.0 2.3 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK64390.1 - 0.0044 17.6 0.2 0.012 16.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK64390.1 - 0.19 11.4 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C21 PF05381.12 KIK64392.1 - 0.058 13.7 0.1 4.5 7.6 0.0 2.4 2 1 0 2 2 2 0 Tymovirus endopeptidase TMEM173 PF15009.6 KIK64392.1 - 0.14 11.3 0.9 0.29 10.3 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 173 zf-MYND PF01753.18 KIK64393.1 - 1.8e-11 43.9 8.8 2.8e-11 43.3 8.8 1.3 1 0 0 1 1 1 1 MYND finger zinc_ribbon_12 PF11331.8 KIK64393.1 - 0.028 14.2 2.1 0.045 13.6 2.1 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-C6H2 PF15801.5 KIK64393.1 - 0.15 12.4 6.6 0.086 13.2 3.8 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DLH PF01738.18 KIK64394.1 - 2.1e-17 63.4 0.0 2.4e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family WSC PF01822.19 KIK64395.1 - 1.9e-26 92.1 13.5 8.2e-17 61.2 5.8 2.4 2 1 0 2 2 2 2 WSC domain GMC_oxred_N PF00732.19 KIK64396.1 - 4.9e-53 180.4 0.0 9.3e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK64396.1 - 2e-33 115.9 0.0 4.1e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KIK64396.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KIK64396.1 - 0.012 15.2 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK64396.1 - 0.017 14.4 0.5 0.6 9.3 0.4 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK64396.1 - 0.023 13.8 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK64396.1 - 0.054 13.7 0.1 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KIK64397.1 - 7.3e-53 179.9 0.0 1.1e-52 179.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK64397.1 - 2.8e-34 118.7 0.0 4.5e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIK64397.1 - 0.0048 16.2 0.5 0.6 9.3 0.4 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK64397.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK64397.1 - 0.017 14.7 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK64397.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK64397.1 - 0.057 13.6 0.0 0.31 11.3 0.0 2.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mito_carr PF00153.27 KIK64398.1 - 2e-30 104.6 3.8 1.6e-16 60.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 KIK64399.1 - 1.5e-08 34.4 0.0 4.9e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64399.1 - 1.8e-05 24.4 0.0 0.0001 22.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64399.1 - 5.2e-05 23.2 0.0 8.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK64399.1 - 0.0015 18.8 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 KIK64399.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) ER_lumen_recept PF00810.18 KIK64400.1 - 5.3e-31 108.4 8.7 5.3e-31 108.4 8.7 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF1516 PF07457.11 KIK64400.1 - 0.022 15.0 0.8 0.047 13.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) PQ-loop PF04193.14 KIK64400.1 - 5.8 6.8 10.4 0.87 9.4 0.2 3.6 4 0 0 4 4 4 0 PQ loop repeat ER_lumen_recept PF00810.18 KIK64401.1 - 5.2e-29 102.0 6.9 6.6e-29 101.6 6.9 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KIK64401.1 - 0.043 13.6 6.5 0.32 10.8 0.4 3.1 2 1 1 3 3 3 0 PQ loop repeat SH3-RhoG_link PF16609.5 KIK64402.1 - 0.086 12.6 0.1 0.091 12.5 0.1 1.1 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region DIOX_N PF14226.6 KIK64403.1 - 6.7e-12 46.2 0.0 1.7e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK64403.1 - 0.013 16.0 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Bax1-I PF01027.20 KIK64406.1 - 0.11 12.3 10.1 0.14 12.0 10.1 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Methyltransf_10 PF05971.12 KIK64407.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_10 PF05971.12 KIK64410.1 - 1.9e-09 37.3 0.4 2.9e-05 23.5 0.1 2.0 1 1 1 2 2 2 2 RNA methyltransferase Methyltransf_10 PF05971.12 KIK64411.1 - 1e-13 51.3 0.0 4.4e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 RNA methyltransferase Methyltransf_10 PF05971.12 KIK64412.1 - 1.3e-65 221.7 0.0 1.6e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase TrmK PF04816.12 KIK64412.1 - 0.0074 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase PrmA PF06325.13 KIK64412.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KIK64412.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FA_desaturase PF00487.24 KIK64413.1 - 0.35 10.7 3.1 0.69 9.7 3.1 1.5 1 1 0 1 1 1 0 Fatty acid desaturase Methyltransf_10 PF05971.12 KIK64414.1 - 1.4e-07 31.2 1.8 9e-06 25.2 0.4 2.9 1 1 1 2 2 2 2 RNA methyltransferase GDA1_CD39 PF01150.17 KIK64415.1 - 1.4e-08 33.8 0.0 3.1e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Spo0A_C PF08769.11 KIK64415.1 - 0.1 12.7 0.5 0.27 11.4 0.5 1.7 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Z1 PF10593.9 KIK64415.1 - 0.15 11.5 1.6 0.34 10.4 1.6 1.5 1 0 0 1 1 1 0 Z1 domain Seryl_tRNA_N PF02403.22 KIK64415.1 - 0.46 10.7 7.2 0.94 9.7 7.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V-ATPase_G_2 PF16999.5 KIK64415.1 - 0.78 10.2 11.0 0.25 11.8 8.0 1.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Sec62 PF03839.16 KIK64416.1 - 0.077 12.5 0.0 0.082 12.4 0.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DIOX_N PF14226.6 KIK64417.1 - 1.4e-12 48.4 0.0 2.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK64417.1 - 0.0059 17.1 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA_5 PF16577.5 KIK64421.1 - 0.11 12.7 0.2 0.67 10.1 0.0 2.4 3 0 0 3 3 3 0 UBA domain DIOX_N PF14226.6 KIK64425.1 - 2.1e-13 51.1 0.0 3.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK64425.1 - 0.0013 19.1 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF373 PF04123.13 KIK64431.1 - 0.078 12.4 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Retrotran_gag_2 PF14223.6 KIK64432.1 - 7.9e-09 35.3 0.1 2.4e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type SCAB-ABD PF16711.5 KIK64432.1 - 0.14 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein ResIII PF04851.15 KIK64433.1 - 0.027 14.5 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK64433.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 KIK64433.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KIK64437.1 - 4.5e-07 29.9 0.2 1.9e-06 27.9 0.2 1.9 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK64437.1 - 4.4e-05 22.8 0.2 8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK64437.1 - 0.0096 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KIK64437.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK64437.1 - 0.03 14.3 0.0 0.26 11.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK64437.1 - 0.032 14.2 0.0 0.091 12.7 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK64437.1 - 0.037 14.4 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 KIK64437.1 - 0.081 12.1 0.2 0.29 10.3 0.2 1.7 1 1 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.20 KIK64437.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK64437.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CSN4_RPN5_eIF3a PF18420.1 KIK64441.1 - 0.059 13.5 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Ank_4 PF13637.6 KIK64442.1 - 8.9e-16 58.0 0.1 9.9e-10 38.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK64442.1 - 1e-11 44.7 0.4 0.00019 21.7 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIK64442.1 - 2.2e-10 39.9 0.0 0.00039 20.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KIK64442.1 - 2.2e-10 41.0 0.1 4.1e-10 40.1 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK64442.1 - 7.2e-07 29.4 0.3 0.0045 17.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KIK64442.1 - 0.092 12.6 0.7 4.2 7.3 0.1 2.1 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain TTc_toxin_rep PF18807.1 KIK64442.1 - 0.1 12.4 0.1 4.6 7.1 0.0 2.1 1 1 1 2 2 2 0 Tripartite Tc toxins repeat Turandot PF07240.11 KIK64442.1 - 0.1 12.6 0.9 18 5.4 0.0 2.8 2 1 1 3 3 3 0 Stress-inducible humoral factor Turandot Met_10 PF02475.16 KIK64444.1 - 0.06 13.1 0.5 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Met-10+ like-protein CxC2 PF18803.1 KIK64449.1 - 0.0012 19.0 0.7 0.0014 18.7 0.6 1.3 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF678 PF05077.12 KIK64449.1 - 0.023 14.8 0.3 0.03 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Big_3_4 PF13754.6 KIK64456.1 - 0.078 12.7 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function ResIII PF04851.15 KIK64457.1 - 0.02 14.9 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK64457.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Tankyrase_bdg_C PF15327.6 KIK64459.1 - 0.53 10.7 14.5 0.063 13.7 9.6 1.8 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain Retrotran_gag_2 PF14223.6 KIK64462.1 - 5.9e-05 22.7 0.2 0.0001 22.0 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIK64462.1 - 0.018 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KIK64462.1 - 0.084 12.6 1.1 0.23 11.2 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Com_YlbF PF06133.11 KIK64462.1 - 0.11 13.1 2.5 0.22 12.1 2.5 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Retrotrans_gag PF03732.17 KIK64462.1 - 1.6 9.0 3.7 2 8.8 0.1 2.8 4 0 0 4 4 4 0 Retrotransposon gag protein zf-CCHC PF00098.23 KIK64462.1 - 6.8 7.0 11.6 0.086 13.0 4.3 1.8 2 0 0 2 2 2 0 Zinc knuckle TFR_dimer PF04253.15 KIK64465.1 - 0.068 13.3 0.3 2.3 8.4 0.1 2.5 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain DUF4028 PF13220.6 KIK64465.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) CheW PF01584.19 KIK64466.1 - 0.037 13.6 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 CheW-like domain Ribonuclease_3 PF00636.26 KIK64467.1 - 0.02 15.5 0.0 0.025 15.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK64467.1 - 0.078 13.1 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like TraH PF06122.11 KIK64467.1 - 0.16 11.3 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Retrotran_gag_2 PF14223.6 KIK64473.1 - 0.17 11.5 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NACHT PF05729.12 KIK64474.1 - 0.019 14.9 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIK64474.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ComC PF03047.14 KIK64477.1 - 0.19 11.5 0.2 0.48 10.3 0.2 1.7 1 0 0 1 1 1 0 COMC family SOG2 PF10428.9 KIK64479.1 - 0.0092 15.2 2.4 0.011 14.9 2.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein SOGA PF11365.8 KIK64479.1 - 0.055 14.6 0.8 0.12 13.5 0.8 1.5 1 0 0 1 1 1 0 Protein SOGA DUF3450 PF11932.8 KIK64479.1 - 0.085 12.1 2.4 4.6 6.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2554 PF10829.8 KIK64479.1 - 0.32 11.4 2.4 1.7 9.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2554) Syntaxin-6_N PF09177.11 KIK64479.1 - 0.52 10.9 3.1 0.63 10.6 1.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Helicase_C PF00271.31 KIK64483.1 - 8.7e-05 22.8 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_2 PF12796.7 KIK64485.1 - 2.3e-11 44.1 0.3 6.7e-11 42.6 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK64485.1 - 7.6e-11 42.3 0.1 0.00048 20.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK64485.1 - 8.4e-10 38.0 0.3 0.0092 16.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIK64485.1 - 1.9e-08 34.4 3.4 0.0026 18.2 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.12 KIK64485.1 - 1.1e-06 28.7 0.1 6.5e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KIK64485.1 - 1.9e-06 28.0 2.3 0.001 19.3 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NB-ARC PF00931.22 KIK64485.1 - 0.0015 17.8 0.5 0.0065 15.7 0.4 2.0 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KIK64485.1 - 0.065 12.5 0.3 0.16 11.2 0.3 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KIK64485.1 - 0.073 13.5 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KIK64485.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF2200 PF09966.9 KIK64485.1 - 0.08 13.1 0.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) AAA_14 PF13173.6 KIK64485.1 - 0.086 12.9 1.8 1.7 8.7 0.0 3.6 3 1 1 4 4 4 0 AAA domain PAS_4 PF08448.10 KIK64485.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold APS_kinase PF01583.20 KIK64485.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_20 PF14561.6 KIK64485.1 - 0.12 12.7 1.5 0.48 10.8 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 KIK64486.1 - 1.2e-13 51.2 0.7 4.3e-07 30.4 0.0 3.7 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK64486.1 - 1.2e-11 45.0 4.2 8.7e-06 26.2 0.1 3.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KIK64486.1 - 2.2e-11 43.7 3.5 0.027 14.9 0.6 4.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KIK64486.1 - 5.6e-11 41.7 0.1 0.43 11.3 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK64486.1 - 3e-05 24.2 0.2 3.1 8.2 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) YajC PF02699.15 KIK64486.1 - 0.017 15.0 0.0 2.9 7.8 0.0 2.3 1 1 1 2 2 2 0 Preprotein translocase subunit NACHT PF05729.12 KIK64487.1 - 3.5e-06 27.0 0.2 1.2e-05 25.3 0.2 1.8 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK64487.1 - 0.00036 19.8 1.4 0.0015 17.8 0.4 2.0 1 1 1 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 KIK64487.1 - 0.057 13.5 0.1 0.6 10.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK64487.1 - 0.069 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KIK64487.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 KIK64487.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Ank_4 PF13637.6 KIK64492.1 - 2.8e-22 78.8 0.6 4e-10 40.0 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK64492.1 - 9.5e-19 67.8 0.5 6.4e-15 55.5 0.4 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK64492.1 - 4e-17 61.8 1.1 2.2e-05 24.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KIK64492.1 - 3.4e-15 54.6 0.1 0.00039 20.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK64492.1 - 7.1e-09 35.8 1.1 0.00032 20.9 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF4208 PF13907.6 KIK64492.1 - 0.095 13.1 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DUF1843 PF08898.10 KIK64492.1 - 0.26 11.8 3.5 6.5 7.3 0.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) DUF1682 PF07946.14 KIK64493.1 - 0.055 12.7 0.1 0.063 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DEAD PF00270.29 KIK64494.1 - 0.0002 21.2 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK64494.1 - 0.19 11.7 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Phage_tail_NK PF16532.5 KIK64496.1 - 0.023 14.3 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales NACHT PF05729.12 KIK64500.1 - 1.2e-05 25.3 0.1 3.7e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK64500.1 - 0.0019 17.4 0.4 0.0062 15.8 0.4 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KIK64500.1 - 0.022 14.8 0.0 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK64500.1 - 0.039 13.9 0.1 0.081 12.8 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KIK64500.1 - 0.044 13.0 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KIK64500.1 - 0.076 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK64500.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KIK64500.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PIG-S PF10510.9 KIK64502.1 - 0.0061 15.5 0.2 0.0087 14.9 0.1 1.4 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein zf-BED PF02892.15 KIK64505.1 - 0.013 15.5 1.9 0.031 14.3 1.9 1.6 1 0 0 1 1 1 0 BED zinc finger AAA_13 PF13166.6 KIK64505.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain KDZ PF18758.1 KIK64507.1 - 4.9e-25 88.4 0.3 7.1e-25 87.9 0.3 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Plavaka PF18759.1 KIK64510.1 - 3.8e-47 161.1 0.2 4.2e-47 160.9 0.2 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK64511.1 - 0.0015 17.9 0.7 0.0023 17.2 0.7 1.3 1 0 0 1 1 1 1 Plavaka transposase KDZ PF18758.1 KIK64513.1 - 8.4e-30 104.0 0.2 1.3e-29 103.4 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF1182 PF06681.13 KIK64515.1 - 0.028 14.0 6.3 0.17 11.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) PBC PF03792.13 KIK64515.1 - 0.14 11.9 0.2 55 3.4 0.0 3.8 2 2 3 5 5 5 0 PBC domain DUF5400 PF17379.2 KIK64515.1 - 0.17 12.3 10.0 2.1 8.9 1.6 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5400) DUF3785 PF12653.7 KIK64515.1 - 0.51 10.4 13.4 15 5.7 0.2 5.3 2 1 4 6 6 6 0 Protein of unknown function (DUF3785) NACHT PF05729.12 KIK64516.1 - 0.082 12.8 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain NACHT PF05729.12 KIK64517.1 - 0.013 15.4 0.2 0.023 14.6 0.1 1.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KIK64517.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF1263 PF06882.12 KIK64518.1 - 0.024 14.7 0.3 1 9.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) Ribonuclease_3 PF00636.26 KIK64520.1 - 1.6e-06 28.7 0.0 2.6e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK64520.1 - 2.4e-06 27.7 0.0 0.073 13.2 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 KIK64522.1 - 2.5e-12 47.1 0.0 7.1e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK64522.1 - 0.00017 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 KIK64522.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Oxidored_q3 PF00499.20 KIK64523.1 - 0.075 12.8 3.5 0.21 11.3 3.5 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Glyco_hydro_3_C PF01915.22 KIK64526.1 - 6.4e-64 215.7 0.0 1e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK64526.1 - 3.6e-45 154.7 0.0 6.9e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK64526.1 - 5e-23 81.0 0.3 1.4e-22 79.6 0.3 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIK64526.1 - 5.2e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain F-box-like PF12937.7 KIK64527.1 - 1.4e-05 24.9 3.3 4.2e-05 23.4 2.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK64527.1 - 0.0032 17.8 2.2 8.2 7.0 0.2 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK64528.1 - 0.00014 21.7 0.6 0.00014 21.7 0.6 2.8 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KIK64529.1 - 2.9e-06 27.1 0.4 0.00018 21.3 0.2 2.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK64529.1 - 1.7 9.2 7.9 3.2 8.3 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK64529.1 - 5.9 6.9 8.5 2 8.4 0.2 3.5 4 0 0 4 4 4 0 F-box domain Toxin_3 PF00537.18 KIK64530.1 - 0.016 15.4 4.5 0.016 15.4 4.5 1.9 2 0 0 2 2 2 0 Scorpion toxin-like domain SLR1-BP PF07333.12 KIK64530.1 - 0.052 14.0 6.8 0.052 14.0 6.8 1.9 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) TIL PF01826.17 KIK64530.1 - 0.19 12.0 7.4 0.35 11.1 7.3 1.5 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain GATA PF00320.27 KIK64531.1 - 7e-11 41.5 6.3 1.2e-10 40.8 6.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-C4H2 PF10146.9 KIK64531.1 - 0.14 12.5 6.1 0.17 12.2 6.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Nup54_C PF18437.1 KIK64531.1 - 0.16 11.9 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain zf-RRN7 PF11781.8 KIK64531.1 - 0.17 11.6 4.9 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 KIK64531.1 - 0.23 11.4 1.4 0.44 10.4 1.4 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Nudix_N_2 PF14803.6 KIK64531.1 - 0.61 10.0 5.9 14 5.7 5.8 2.3 1 1 1 2 2 2 0 Nudix N-terminal GATA PF00320.27 KIK64532.1 - 1.4e-17 63.0 2.6 1.7e-17 62.7 2.6 1.2 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KIK64532.1 - 0.0072 16.4 0.2 0.0074 16.4 0.2 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 KIK64532.1 - 0.013 15.0 1.7 0.024 14.1 1.8 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KIK64532.1 - 0.017 14.6 2.5 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 KIK64532.1 - 0.051 13.7 0.2 0.071 13.3 0.2 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KIK64532.1 - 0.072 13.1 1.9 0.63 10.1 2.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KIK64532.1 - 0.074 13.2 0.2 0.11 12.6 0.2 1.4 1 1 0 1 1 1 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 KIK64532.1 - 0.11 12.4 0.3 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Rubredoxin_2 PF18073.1 KIK64532.1 - 0.11 12.2 1.4 5.8 6.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Vac_Fusion PF02346.16 KIK64533.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 HMG_box PF00505.19 KIK64538.1 - 2.6e-10 40.6 0.0 5.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK64538.1 - 0.00075 20.0 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF3483 PF11982.8 KIK64539.1 - 0.031 13.9 1.1 0.031 13.9 1.1 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3483) Wzy_C_2 PF11846.8 KIK64539.1 - 0.43 10.5 9.0 0.049 13.6 1.5 2.5 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal VPS13 PF16908.5 KIK64541.1 - 0.0018 18.1 0.3 0.0049 16.7 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Sugarporin_N PF11471.8 KIK64541.1 - 0.019 14.9 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension EF-hand_1 PF00036.32 KIK64541.1 - 0.13 11.9 0.0 0.54 9.9 0.0 2.1 1 0 0 1 1 1 0 EF hand Gal4_dimer PF03902.13 KIK64541.1 - 1.7 8.9 7.4 2.7 8.2 0.2 4.1 2 2 2 4 4 4 0 Gal4-like dimerisation domain Aldo_ket_red PF00248.21 KIK64542.1 - 7.4e-68 228.9 0.0 8.4e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KIK64543.1 - 0.00026 20.5 0.0 0.0098 15.4 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 KIK64544.1 - 5.9e-27 94.4 0.0 2.5e-25 89.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64544.1 - 1e-10 41.6 0.0 4.9e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64544.1 - 7.2e-06 26.0 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 KIK64544.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KIK64545.1 - 5.4e-69 232.6 0.0 6.1e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1160 PF06648.11 KIK64545.1 - 0.14 12.2 0.4 0.58 10.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) DUF3759 PF12585.8 KIK64546.1 - 1.8e-35 120.8 10.4 2.2e-35 120.6 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) NmrA PF05368.13 KIK64547.1 - 9.7e-24 84.2 0.0 1.3e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK64547.1 - 6.1e-07 29.5 0.0 9.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding CLZ PF16526.5 KIK64548.1 - 0.00021 21.6 2.0 0.016 15.6 0.0 3.8 3 0 0 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels VPS13 PF16908.5 KIK64548.1 - 0.00088 19.1 1.2 0.0025 17.7 1.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal CDC37_M PF08565.11 KIK64548.1 - 0.011 15.6 0.7 0.036 14.0 0.7 1.8 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain Sugarporin_N PF11471.8 KIK64548.1 - 0.044 13.7 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ZYG-11_interact PF05884.12 KIK64548.1 - 0.11 11.9 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 Peptidase_C92 PF05708.12 KIK64552.1 - 0.061 13.4 0.3 0.07 13.2 0.3 1.1 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Plavaka PF18759.1 KIK64561.1 - 2.7e-58 197.7 0.0 3e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Acyl_transf_1 PF00698.21 KIK64562.1 - 2.1e-13 50.5 0.0 5e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Acyl transferase domain OPT PF03169.15 KIK64563.1 - 1.9e-07 30.1 0.9 2.3e-07 29.9 0.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein COG5 PF10392.9 KIK64565.1 - 0.014 15.6 7.2 0.014 15.6 7.2 5.5 1 1 2 5 5 5 0 Golgi transport complex subunit 5 DUF2046 PF09755.9 KIK64567.1 - 0.016 14.5 2.2 0.35 10.1 0.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) GlnD_UR_UTase PF08335.11 KIK64567.1 - 0.09 12.9 0.6 0.17 11.9 0.6 1.5 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase SHE3 PF17078.5 KIK64567.1 - 0.091 12.5 3.5 0.046 13.4 1.1 1.7 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DOT1 PF08123.13 KIK64568.1 - 1.5e-43 148.7 0.0 1.7e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 KIK64568.1 - 0.00097 18.5 0.1 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KIK64568.1 - 0.0073 16.1 0.7 0.016 15.0 0.7 1.4 1 1 0 1 1 1 1 Methyltransferase domain Snapin_Pallidin PF14712.6 KIK64569.1 - 0.015 15.7 0.2 3.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin SAT PF16073.5 KIK64572.1 - 4.2e-07 29.9 0.1 5e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FMN_bind PF04205.14 KIK64572.1 - 0.12 13.0 0.3 0.17 12.5 0.3 1.3 1 0 0 1 1 1 0 FMN-binding domain MaoC_dehydrat_N PF13452.6 KIK64575.1 - 9.6e-06 25.8 0.0 1.1e-05 25.6 0.0 1.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TSC22 PF01166.18 KIK64577.1 - 0.0069 16.7 5.1 0.76 10.1 0.2 3.3 3 1 1 4 4 4 2 TSC-22/dip/bun family BLOC1_2 PF10046.9 KIK64577.1 - 0.0086 16.4 7.9 5.8 7.3 3.8 3.3 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 KIK64577.1 - 0.01 16.1 9.0 0.38 11.0 1.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2203 PF09969.9 KIK64577.1 - 0.021 15.5 3.8 0.31 11.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Lipase_2 PF01674.18 KIK64577.1 - 0.051 13.1 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 2) CdvA PF18822.1 KIK64577.1 - 0.061 13.1 0.6 0.061 13.1 0.6 2.5 2 1 0 2 2 2 0 CdvA-like coiled-coil domain YueH PF14166.6 KIK64577.1 - 0.063 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 YueH-like protein DUF4279 PF14106.6 KIK64577.1 - 0.068 13.4 0.4 2.6 8.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) FlxA PF14282.6 KIK64577.1 - 0.076 13.0 0.1 0.076 13.0 0.1 2.4 2 1 0 2 2 2 0 FlxA-like protein YPEB PF14620.6 KIK64577.1 - 0.089 12.1 3.5 0.32 10.3 3.5 1.7 1 1 0 1 1 1 0 YpeB sporulation CENP-F_leu_zip PF10473.9 KIK64577.1 - 0.29 11.2 11.8 0.66 10.0 0.6 3.2 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KIK64577.1 - 0.35 11.3 10.7 11 6.4 10.7 2.3 1 1 0 1 1 1 0 Fez1 Filament PF00038.21 KIK64577.1 - 0.39 10.3 8.5 0.71 9.4 0.9 2.0 2 0 0 2 2 2 0 Intermediate filament protein Lectin_N PF03954.14 KIK64577.1 - 0.53 10.0 4.8 1.2 8.9 0.3 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 KIK64577.1 - 0.69 10.0 6.1 18 5.4 3.7 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KIK64577.1 - 0.75 8.3 2.5 1.4 7.3 0.2 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family CC2-LZ PF16516.5 KIK64577.1 - 0.84 10.0 8.3 0.44 11.0 0.4 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 KIK64577.1 - 0.99 8.2 13.0 0.3 9.9 3.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KIK64577.1 - 1.1 8.8 12.8 1.6 8.2 4.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 KIK64577.1 - 1.2 9.8 7.6 11 6.7 0.3 3.3 2 2 1 3 3 3 0 SlyX DUF5082 PF16888.5 KIK64577.1 - 1.3 9.3 8.3 0.96 9.7 1.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 KIK64577.1 - 1.8 9.1 10.8 0.11 12.9 1.3 2.8 2 1 0 2 2 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 KIK64577.1 - 2.3 8.8 7.4 2e+02 2.6 6.0 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.6 KIK64577.1 - 2.8 8.1 10.2 0.32 11.1 0.5 3.2 2 2 0 3 3 3 0 Centrosome localisation domain of PPC89 OmpH PF03938.14 KIK64577.1 - 5.3 7.4 12.9 4.8 7.5 2.9 2.4 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KIK64577.1 - 5.4 7.1 15.6 0.93 9.6 3.5 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Histone_HNS PF00816.21 KIK64577.1 - 6.2 7.7 7.3 2.2 9.2 1.0 2.3 2 0 0 2 2 2 0 H-NS histone family Bap31_Bap29_C PF18035.1 KIK64577.1 - 9.4 6.3 11.5 2.3 8.3 0.8 3.5 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain WD40 PF00400.32 KIK64579.1 - 0.042 14.7 0.3 34 5.5 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ PF01011.21 KIK64579.1 - 0.095 12.7 0.1 1.4 9.0 0.0 2.9 4 0 0 4 4 4 0 PQQ enzyme repeat RHS PF03527.14 KIK64579.1 - 0.1 12.3 1.1 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 RHS protein Lactonase PF10282.9 KIK64579.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Calcipressin PF04847.12 KIK64579.1 - 0.38 10.5 2.3 0.62 9.8 2.3 1.2 1 0 0 1 1 1 0 Calcipressin Retrotrans_gag PF03732.17 KIK64580.1 - 0.041 14.2 0.1 0.077 13.3 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Mltc_N PF11873.8 KIK64580.1 - 0.041 13.6 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain p450 PF00067.22 KIK64581.1 - 5.4e-59 200.1 0.0 9.2e-59 199.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 KIK64582.1 - 3.4e-28 99.2 3.2 5.7e-14 52.4 2.7 3.0 2 2 0 2 2 2 2 Serine carboxypeptidase Peptidase_S10 PF00450.22 KIK64583.1 - 4e-60 204.4 0.0 2.8e-59 201.6 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KIK64583.1 - 0.03 13.6 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3552 PF12072.8 KIK64584.1 - 0.017 14.6 74.5 0.025 14.0 12.0 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3552) DUF416 PF04222.12 KIK64589.1 - 0.11 11.9 0.2 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Rab5ip PF07019.12 KIK64592.1 - 3.8e-14 53.0 10.3 8.9e-14 51.8 10.3 1.6 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Tannase PF07519.11 KIK64593.1 - 2.1e-102 343.5 0.2 3.1e-58 197.8 0.1 2.1 1 1 0 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KIK64593.1 - 0.023 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK64593.1 - 0.032 13.7 0.1 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK64593.1 - 0.041 13.2 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ca_chan_IQ PF08763.11 KIK64594.1 - 0.18 12.1 1.0 19 5.5 0.1 2.6 2 1 1 3 3 3 0 Voltage gated calcium channel IQ domain Aldedh PF00171.22 KIK64595.1 - 1.7e-25 89.5 0.0 2e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_2 PF00891.18 KIK64596.1 - 3.8e-26 91.7 0.0 2e-24 86.0 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KIK64596.1 - 0.17 11.7 0.0 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain SRP-alpha_N PF04086.13 KIK64597.1 - 0.011 15.7 7.4 0.012 15.6 7.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ferlin_C PF16165.5 KIK64597.1 - 0.38 10.7 1.3 0.44 10.5 1.3 1.2 1 0 0 1 1 1 0 Ferlin C-terminus LZ_Tnp_IS66 PF13007.7 KIK64597.1 - 1.3 9.9 7.1 0.44 11.3 3.9 1.8 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain Aldedh PF00171.22 KIK64598.1 - 9.5e-107 357.4 0.1 1.2e-106 357.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sirohm_synth_M PF14824.6 KIK64599.1 - 0.17 11.4 0.5 0.3 10.6 0.2 1.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central CMAS PF02353.20 KIK64600.1 - 6.4e-24 84.7 0.1 1.2e-23 83.8 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK64600.1 - 0.0019 18.8 0.0 0.0039 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK64600.1 - 0.037 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KIK64600.1 - 0.045 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_11 PF08241.12 KIK64600.1 - 0.08 13.6 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIK64600.1 - 0.081 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Abhydrolase_6 PF12697.7 KIK64601.1 - 3.5e-07 31.1 0.0 2.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cullin PF00888.22 KIK64602.1 - 1e-185 619.0 20.1 1.6e-185 618.3 20.1 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK64602.1 - 4.5e-27 93.9 2.7 1.6e-26 92.1 2.7 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.20 KIK64602.1 - 0.02 15.3 1.1 0.078 13.3 0.2 2.3 2 0 0 2 2 2 0 Transcriptional regulator Fibritin_C PF07921.12 KIK64602.1 - 0.12 12.5 0.3 2 8.6 0.0 2.6 2 1 0 2 2 2 0 Fibritin C-terminal region Penicillinase_R PF03965.16 KIK64602.1 - 1.6 9.1 8.7 3.5 8.0 0.1 4.3 4 0 0 4 4 4 0 Penicillinase repressor GST_N_3 PF13417.6 KIK64604.1 - 4.6e-16 59.0 0.0 7.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK64604.1 - 2.6e-13 50.1 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK64604.1 - 1.6e-07 31.6 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK64605.1 - 5.5e-12 45.9 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK64605.1 - 9.3e-11 41.9 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK64605.1 - 2.2e-06 27.9 0.0 5.5e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK64605.1 - 0.15 12.1 0.0 0.99 9.5 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GMC_oxred_N PF00732.19 KIK64607.1 - 4.6e-42 144.4 0.0 6.2e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK64607.1 - 1.9e-23 83.6 0.1 3.3e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KIK64607.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK64607.1 - 0.047 13.9 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK64607.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Abhydrolase_6 PF12697.7 KIK64608.1 - 0.0074 16.9 0.1 0.011 16.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 KIK64608.1 - 0.051 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KIK64609.1 - 0.0018 18.9 0.1 0.0023 18.6 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 KIK64609.1 - 0.045 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 KIK64609.1 - 0.096 12.4 0.0 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family 4HBT PF03061.22 KIK64613.1 - 0.032 14.6 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Corona_NS4 PF03905.13 KIK64613.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 DUF2173 PF09941.9 KIK64617.1 - 0.0047 17.2 0.1 0.0092 16.3 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2173) MscS_porin PF12795.7 KIK64617.1 - 0.0084 15.7 0.4 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 KIK64618.1 - 0.36 11.0 2.8 0.57 10.4 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family VHS PF00790.19 KIK64619.1 - 8.4e-08 32.2 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 VHS domain Herpes_TAF50 PF03326.13 KIK64619.1 - 0.057 12.1 4.1 0.075 11.7 4.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) 2OG-FeII_Oxy_2 PF13532.6 KIK64620.1 - 9.3e-09 35.7 0.0 1.9e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LysM PF01476.20 KIK64621.1 - 3.3e-26 91.1 0.1 1.4e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 LysM domain GRDB PF07355.12 KIK64621.1 - 0.05 12.8 0.2 5.8 6.1 0.1 2.1 1 1 1 2 2 2 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Srg PF02118.21 KIK64622.1 - 0.00012 21.9 11.1 0.00018 21.2 11.1 1.3 1 0 0 1 1 1 1 Srg family chemoreceptor STE3 PF02076.15 KIK64622.1 - 0.0051 16.1 12.1 0.0093 15.2 11.8 1.6 1 1 0 1 1 1 1 Pheromone A receptor SET PF00856.28 KIK64626.1 - 1e-11 45.6 0.0 1.5e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIK64626.1 - 4.2e-10 39.5 11.7 4.2e-10 39.5 11.7 2.8 2 1 0 2 2 2 1 MYND finger DDE_1 PF03184.19 KIK64629.1 - 8.1e-16 58.2 0.1 1.1e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCCH_2 PF14608.6 KIK64630.1 - 0.68 10.5 2.7 1.8 9.2 2.7 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RVT_thumb PF06817.14 KIK64631.1 - 0.00059 19.6 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase thumb domain SET PF00856.28 KIK64634.1 - 3.2e-11 43.9 0.0 8.8e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIK64634.1 - 1.5e-07 31.3 7.7 1.5e-07 31.3 7.7 2.7 2 1 1 3 3 3 1 MYND finger DUF3658 PF12395.8 KIK64636.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3658 PF12395.8 KIK64638.1 - 0.087 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DLH PF01738.18 KIK64639.1 - 1.2e-09 38.1 0.0 0.00025 20.7 0.0 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family MliC PF09864.9 KIK64640.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF1192 PF06698.11 KIK64640.1 - 3.9 7.6 5.2 1.9 8.6 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) UCH PF00443.29 KIK64641.1 - 4.4e-32 111.6 0.0 1e-31 110.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK64641.1 - 6.2e-05 22.7 0.6 0.00015 21.5 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Vps55 PF04133.14 KIK64641.1 - 0.29 11.1 2.7 0.64 10.0 2.7 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Cellulase PF00150.18 KIK64643.1 - 2e-12 47.1 0.4 3e-12 46.5 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HNH_2 PF13391.6 KIK64646.1 - 0.0023 18.0 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 KIK64647.1 - 3.4e-43 147.9 0.0 4.2e-25 88.6 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64647.1 - 3.6e-12 46.1 0.0 5.2e-10 39.0 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KIK64647.1 - 0.00018 21.5 0.1 0.0004 20.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK64647.1 - 0.022 14.4 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pantoate_transf PF02548.15 KIK64648.1 - 1.9e-74 250.4 0.0 2.3e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KIK64648.1 - 2.7e-05 23.7 0.0 6.8e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Cas_Csm6 PF09659.10 KIK64648.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) WD40 PF00400.32 KIK64650.1 - 7.4e-112 362.1 80.3 2.2e-10 40.9 1.4 13.5 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64650.1 - 1.5e-43 147.0 5.5 0.025 14.9 0.0 12.1 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64650.1 - 1.2e-16 60.6 9.8 2 7.3 0.0 11.0 1 1 8 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK64650.1 - 4.6e-10 39.7 0.0 0.031 14.2 0.0 5.2 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 KIK64650.1 - 4.7e-09 36.4 0.0 2.2e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KIK64650.1 - 2.3e-08 33.7 0.1 5 6.4 0.0 8.2 6 3 5 11 11 11 1 WD40-like domain PD40 PF07676.12 KIK64650.1 - 1.3e-07 31.4 35.3 8.3 6.5 0.2 12.1 12 0 0 12 12 12 3 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK64650.1 - 3.2e-06 26.8 2.0 42 4.3 0.0 8.8 10 0 0 10 10 10 0 PQQ enzyme repeat PQQ_2 PF13360.6 KIK64650.1 - 0.0011 18.6 31.7 0.32 10.5 3.1 6.2 2 1 4 6 6 6 3 PQQ-like domain Me-amine-dh_H PF06433.11 KIK64650.1 - 0.0045 15.9 0.1 17 4.2 0.0 4.4 2 2 2 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 KIK64650.1 - 0.0057 17.1 0.0 0.018 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK64650.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 KIK64650.1 - 0.035 14.0 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase HTH_11 PF08279.12 KIK64650.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 HTH domain RNA_helicase PF00910.22 KIK64650.1 - 0.046 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase HTH_24 PF13412.6 KIK64650.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AAA_33 PF13671.6 KIK64650.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Fe_dep_repress PF01325.19 KIK64650.1 - 0.16 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RicinB_lectin_2 PF14200.6 KIK64650.1 - 0.43 11.3 7.6 2.5 8.9 0.3 4.4 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like NACHT PF05729.12 KIK64653.1 - 0.00037 20.5 0.1 0.0013 18.7 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK64653.1 - 0.00093 19.6 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK64653.1 - 0.0076 15.5 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK64653.1 - 0.0078 16.6 0.0 0.02 15.3 0.0 1.7 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 KIK64653.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 KIK64653.1 - 0.022 14.7 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK64653.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK64653.1 - 0.039 14.1 0.1 0.065 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK64653.1 - 0.048 13.0 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KIK64653.1 - 0.06 13.8 0.1 0.074 13.5 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIK64653.1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KIK64653.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK64653.1 - 0.095 11.8 0.5 0.15 11.1 0.1 1.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 HHH_7 PF14635.6 KIK64653.1 - 0.12 12.8 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_18 PF13238.6 KIK64653.1 - 0.13 12.8 0.3 0.17 12.5 0.3 1.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK64653.1 - 0.17 12.0 0.2 0.37 10.9 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KIK64653.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK64654.1 - 3.2e-64 211.3 52.1 1.2e-10 41.8 0.7 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64654.1 - 1.3e-25 89.5 0.5 0.0037 17.5 0.0 7.0 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64654.1 - 2.4e-11 43.2 4.3 0.46 9.4 0.0 6.8 1 1 5 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK64654.1 - 7e-09 35.4 0.1 3.8 6.7 0.0 5.9 5 1 1 6 6 6 2 WD40-like domain PD40 PF07676.12 KIK64654.1 - 5.1e-08 32.7 19.5 2.7 8.0 0.0 8.1 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK64654.1 - 8.4e-05 21.4 9.6 5.4 5.5 0.1 5.9 5 2 1 6 6 6 2 Nucleoporin Nup120/160 DUF4072 PF13284.6 KIK64654.1 - 0.00021 21.7 2.2 51 4.4 0.0 6.1 7 0 0 7 7 7 0 Domain of unknown function (DUF4072) ATP-sulfurylase PF01747.17 KIK64654.1 - 0.00037 20.0 0.0 30 4.0 0.0 5.6 7 0 0 7 7 7 0 ATP-sulfurylase PQQ PF01011.21 KIK64654.1 - 0.00041 20.1 1.9 58 3.9 0.0 5.8 6 0 0 6 6 6 0 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK64654.1 - 0.0018 18.9 0.3 3e+02 2.2 0.0 5.9 7 0 0 7 7 7 0 Cuticle protein DPPIV_N PF00930.21 KIK64654.1 - 0.0069 15.2 0.0 2 7.1 0.0 3.8 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Frtz PF11768.8 KIK64654.1 - 0.014 13.7 0.0 2.4 6.4 0.0 3.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 KIK64654.1 - 0.023 14.7 1.3 2e+02 2.0 0.0 5.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Peptidase_S9_N PF02897.15 KIK64654.1 - 0.046 12.5 5.4 12 4.6 0.0 4.8 1 1 3 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Methyltransf_10 PF05971.12 KIK64654.1 - 0.64 9.3 2.0 19 4.4 0.2 2.7 1 1 1 3 3 3 0 RNA methyltransferase rOmpB PF12334.8 KIK64654.1 - 1.1 8.7 13.0 5.4 6.4 0.0 5.8 5 2 2 7 7 7 0 Rickettsia outer membrane protein B MucBP_2 PF17965.1 KIK64654.1 - 1.8 9.2 10.9 1.6e+02 2.9 0.2 6.1 7 0 0 7 7 7 0 Mucin binding domain Ku_C PF03730.14 KIK64659.1 - 0.21 12.3 0.1 0.21 12.3 0.1 2.3 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm LPAM_2 PF13627.6 KIK64660.1 - 0.081 12.8 0.2 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site KDZ PF18758.1 KIK64662.1 - 3.6e-09 36.5 0.2 4.6e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK64663.1 - 2.5e-25 89.4 0.1 2.8e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK64665.1 - 1.5e-10 41.1 0.1 3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK64666.1 - 2.3e-08 33.9 0.1 2.8e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TRAP_alpha PF03896.16 KIK64668.1 - 0.082 12.1 4.1 0.14 11.3 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.18 KIK64668.1 - 0.083 12.8 4.5 0.037 13.9 2.1 1.6 2 0 0 2 2 2 0 Myc amino-terminal region RPA43_OB PF17875.1 KIK64668.1 - 0.11 13.1 6.7 0.054 14.1 3.0 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I WRNPLPNID PF15017.6 KIK64668.1 - 0.4 11.6 19.4 0.33 11.8 14.3 2.9 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box LAT PF15234.6 KIK64668.1 - 0.62 9.8 5.0 0.35 10.6 2.3 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells DNA_pol_phi PF04931.13 KIK64668.1 - 1.4 6.9 16.6 2.5 6.1 16.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KIK64668.1 - 1.6 8.1 12.0 0.093 12.1 6.5 1.6 2 0 0 2 2 2 0 SDA1 ATHILA PF03078.15 KIK64668.1 - 1.7 7.4 6.3 2.2 7.0 6.3 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Pox_Ag35 PF03286.14 KIK64668.1 - 2.4 7.9 9.8 2.8 7.7 6.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 KIK64668.1 - 4 6.5 7.7 5.7 6.0 7.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MPP6 PF10175.9 KIK64668.1 - 9.1 6.8 11.0 5.9 7.4 6.6 2.2 2 0 0 2 2 2 0 M-phase phosphoprotein 6 S-antigen PF05756.11 KIK64670.1 - 4.7 7.7 7.8 1.6 9.2 0.2 3.0 3 0 0 3 3 3 0 S-antigen protein RRN3 PF05327.11 KIK64671.1 - 6.3 5.2 7.8 8.1 4.9 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dicty_REP PF05086.12 KIK64673.1 - 0.53 8.2 11.9 0.72 7.8 11.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SURF2 PF05477.11 KIK64673.1 - 2.7 7.6 13.3 4.3 7.0 13.3 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Retrotrans_gag PF03732.17 KIK64674.1 - 2.8e-06 27.5 0.0 4.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK64674.1 - 0.067 13.1 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) Chromo PF00385.24 KIK64676.1 - 0.31 11.0 4.8 0.75 9.8 1.0 2.9 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 KIK64677.1 - 0.00035 20.3 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK64677.1 - 0.0017 19.0 0.0 0.0077 16.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK64677.1 - 0.0033 17.9 0.0 0.01 16.4 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Rap1-DNA-bind PF09197.10 KIK64678.1 - 0.14 12.8 2.2 0.22 12.2 0.3 2.1 2 0 0 2 2 2 0 Rap1, DNA-binding ubiquitin PF00240.23 KIK64680.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family CAP_N PF01213.19 KIK64680.1 - 8.2 5.8 6.8 15 5.0 6.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CHCH PF06747.13 KIK64681.1 - 0.00011 22.2 6.0 0.00011 22.2 6.0 2.3 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 KIK64681.1 - 0.0005 20.0 11.0 0.17 11.9 0.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 KIK64681.1 - 3.1 8.1 11.2 0.67 10.2 3.9 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KIK64681.1 - 9.7 6.6 10.8 36 4.8 0.1 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Ribosomal_L10 PF00466.20 KIK64682.1 - 0.00042 20.4 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 BPL_LplA_LipB PF03099.19 KIK64683.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 KIK64683.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Tap-RNA_bind PF09162.10 KIK64684.1 - 0.059 13.2 0.2 0.29 11.0 0.3 1.9 2 0 0 2 2 2 0 Tap, RNA-binding Na_H_antiport_1 PF06965.12 KIK64684.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter 1 NPV_P10 PF05531.12 KIK64684.1 - 0.29 11.6 5.2 1.6 9.3 1.6 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.32 KIK64685.1 - 3.5e-87 284.0 65.4 1.5e-09 38.3 0.5 11.7 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64685.1 - 2.7e-34 117.3 0.9 0.013 15.8 0.0 9.9 1 1 8 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64685.1 - 6.7e-17 61.4 9.7 1.4 7.8 0.0 9.7 1 1 8 10 10 10 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK64685.1 - 2.5e-14 52.8 11.9 6.7 6.8 0.0 10.3 10 0 0 10 10 10 6 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK64685.1 - 6.3e-08 32.7 0.2 2.7e-07 30.7 0.2 2.0 1 1 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KIK64685.1 - 3.4e-07 29.9 0.0 0.64 9.3 0.0 6.3 5 3 1 7 7 7 1 WD40-like domain Cuticle_4 PF15955.5 KIK64685.1 - 0.00013 22.5 1.7 87 3.9 0.0 6.8 8 0 0 8 8 7 0 Cuticle protein AAA_16 PF13191.6 KIK64685.1 - 0.0095 16.3 0.0 0.045 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PQQ PF01011.21 KIK64685.1 - 0.013 15.4 5.3 1.6e+02 2.5 0.0 7.1 8 0 0 8 8 8 0 PQQ enzyme repeat RNA_helicase PF00910.22 KIK64685.1 - 0.035 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK64685.1 - 0.09 12.9 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK64685.1 - 0.091 13.2 0.1 0.28 11.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK64685.1 - 0.19 12.3 0.7 0.66 10.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain HHH_7 PF14635.6 KIK64685.1 - 0.19 12.1 1.4 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif WD40_3 PF15911.5 KIK64685.1 - 0.37 10.8 10.5 1.3e+02 2.7 0.0 7.7 10 0 0 10 10 10 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK64685.1 - 0.69 9.5 20.0 1.7 8.1 3.5 4.1 1 1 1 3 3 3 0 PQQ-like domain rOmpB PF12334.8 KIK64685.1 - 1.3 8.4 13.5 83 2.5 0.1 7.6 8 1 1 9 9 9 0 Rickettsia outer membrane protein B WD40 PF00400.32 KIK64688.1 - 3.1e-106 344.3 84.1 1.9e-10 41.2 0.6 15.4 15 1 0 15 15 15 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64688.1 - 1.6e-37 127.7 1.0 0.011 16.0 0.0 11.7 1 1 11 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64688.1 - 2.7e-21 75.9 7.1 0.26 10.2 0.0 11.0 2 2 8 11 11 11 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK64688.1 - 5.4e-17 61.3 15.4 7.9 6.6 0.0 11.5 12 0 0 12 12 12 7 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK64688.1 - 2.3e-11 43.6 0.0 2.3 7.5 0.0 7.9 6 3 3 10 10 10 2 WD40-like domain NACHT PF05729.12 KIK64688.1 - 2.6e-09 37.2 0.1 7.8e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KIK64688.1 - 1.3e-06 27.3 20.7 2.4 6.7 0.1 9.2 8 1 3 11 11 11 3 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KIK64688.1 - 0.0034 16.2 0.7 17 4.0 0.0 5.8 2 2 3 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_16 PF13191.6 KIK64688.1 - 0.0043 17.5 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.6 KIK64688.1 - 0.0057 16.3 20.5 4.2 6.9 7.5 5.3 2 1 3 5 5 5 2 PQQ-like domain RNA_helicase PF00910.22 KIK64688.1 - 0.04 14.3 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KIK64688.1 - 0.042 13.0 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF4072 PF13284.6 KIK64688.1 - 0.061 13.8 7.7 9.4 6.8 0.1 6.9 11 0 0 11 11 10 0 Domain of unknown function (DUF4072) Parvo_NS1 PF01057.17 KIK64688.1 - 0.079 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HHH_7 PF14635.6 KIK64688.1 - 0.14 12.5 1.4 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif NTPase_1 PF03266.15 KIK64688.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 1 0 1 1 1 0 NTPase MWFE PF15879.5 KIK64690.1 - 2.3e-23 82.1 0.1 2.9e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DUF4446 PF14584.6 KIK64692.1 - 0.013 15.5 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Chordopox_G3 PF06129.12 KIK64692.1 - 0.042 14.6 0.0 0.061 14.0 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus G3 protein pP_pnuc_1 PF18165.1 KIK64692.1 - 0.091 12.7 0.3 0.15 12.0 0.3 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease TB2_DP1_HVA22 PF03134.19 KIK64693.1 - 9.8e-13 47.8 0.8 1.4e-12 47.3 0.4 1.5 1 1 0 1 1 1 1 TB2/DP1, HVA22 family DUF4690 PF15756.5 KIK64697.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Herpes_gE PF02480.16 KIK64697.1 - 0.088 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FYVE PF01363.21 KIK64702.1 - 0.032 14.4 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 FYVE zinc finger DUF983 PF06170.12 KIK64702.1 - 0.13 12.7 0.1 0.18 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) zf-RVT PF13966.6 KIK64704.1 - 0.00011 22.9 4.7 0.00025 21.7 4.7 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK64705.1 - 8.6e-07 28.7 0.3 1.9e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 KIK64708.1 - 1.2e-47 162.8 0.0 1.5e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_ECF PF07638.11 KIK64708.1 - 0.062 13.2 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor DUF1382 PF07131.11 KIK64710.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Rtt102p PF09510.10 KIK64710.1 - 0.037 14.2 0.1 0.097 12.9 0.1 1.7 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein zf-CCHC PF00098.23 KIK64710.1 - 0.93 9.7 3.8 3.9 7.7 3.8 1.9 1 1 0 1 1 1 0 Zinc knuckle DUF983 PF06170.12 KIK64710.1 - 3.6 8.1 5.0 0.37 11.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) MFS_1 PF07690.16 KIK64712.1 - 1.1e-11 44.3 17.0 1.9e-11 43.5 16.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KIK64712.1 - 1e-06 28.4 0.1 1.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KIK64713.1 - 9.9e-10 37.9 21.3 4.4e-09 35.7 21.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM215 PF15746.5 KIK64713.1 - 1.5 8.2 3.1 2.4 7.6 3.1 1.2 1 0 0 1 1 1 0 TMEM215 family Dimer_Tnp_hAT PF05699.14 KIK64715.1 - 2.4e-07 30.4 0.0 2.5e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nodulin-like PF06813.13 KIK64717.1 - 8e-10 38.6 8.2 8e-10 38.6 8.2 2.2 2 0 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 KIK64717.1 - 4.1e-07 29.2 29.9 1.7e-06 27.2 30.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK64718.1 - 1.1e-16 60.8 32.1 6.1e-16 58.3 31.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KIK64718.1 - 2.5e-10 40.3 1.7 2.5e-10 40.3 1.7 2.3 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 KIK64719.1 - 2.1e-05 23.6 31.9 3.1e-05 23.1 29.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TDA11 PF17084.5 KIK64721.1 - 0.055 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 DUF3658 PF12395.8 KIK64722.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function ATP-synt_Eps PF04627.13 KIK64724.1 - 7.3e-17 61.1 0.5 9.6e-17 60.7 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PikAIV_N PF18605.1 KIK64724.1 - 0.051 13.2 0.4 0.078 12.6 0.4 1.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Asp PF00026.23 KIK64725.1 - 1.9e-75 254.2 9.2 2.3e-75 254.0 9.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK64725.1 - 4.9e-10 39.9 8.5 8.1e-08 32.7 8.4 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK64725.1 - 0.0062 16.3 0.1 0.051 13.4 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TMEM135_C_rich PF15982.5 KIK64726.1 - 0.021 15.4 1.7 0.029 15.0 0.3 2.0 2 0 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 DDE_1 PF03184.19 KIK64727.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIK64728.1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1122 PF06557.11 KIK64728.1 - 0.05 13.0 0.3 1.9 7.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1122) Sushi_2 PF09014.10 KIK64728.1 - 0.064 13.2 0.9 0.46 10.4 0.1 2.0 1 1 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Asp PF00026.23 KIK64729.1 - 2.7e-57 194.6 3.2 1.5e-34 119.9 2.5 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK64729.1 - 1.5e-09 38.3 2.8 1.6e-07 31.7 2.8 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK64729.1 - 0.01 15.6 0.3 0.035 13.9 0.2 2.1 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Ndc1_Nup PF09531.10 KIK64729.1 - 0.037 12.7 3.6 0.062 12.0 3.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Retrotrans_gag PF03732.17 KIK64731.1 - 1.5e-07 31.6 0.1 4.8e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein GRAM PF02893.20 KIK64733.1 - 6.1e-06 26.1 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KIK64733.1 - 0.22 11.7 0.0 0.86 9.8 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 DUF3517 PF12030.8 KIK64737.1 - 0.0079 15.1 0.5 0.0096 14.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) GCN5L1 PF06320.13 KIK64737.1 - 0.019 15.1 0.6 0.034 14.3 0.6 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF3658 PF12395.8 KIK64738.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Herpes_US9 PF06072.11 KIK64738.1 - 3.3 7.7 4.7 3.4 7.6 0.0 3.3 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 NAD4L PF06235.11 KIK64739.1 - 0.0011 19.0 1.8 0.0011 19.0 1.8 2.4 2 0 0 2 2 2 1 NADH dehydrogenase subunit 4L (NAD4L) UBA_2 PF08587.11 KIK64740.1 - 0.16 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Amidohydro_2 PF04909.14 KIK64742.1 - 3.7e-26 92.6 0.0 4.6e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase RPN6_C_helix PF18503.1 KIK64742.1 - 0.055 13.2 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain DUF3658 PF12395.8 KIK64744.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function F-box-like PF12937.7 KIK64746.1 - 1.4e-05 24.9 1.6 4.2e-05 23.4 1.6 1.9 1 0 0 1 1 1 1 F-box-like CDC45 PF02724.14 KIK64748.1 - 0.15 10.4 5.8 0.15 10.3 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3504 PF12012.8 KIK64748.1 - 0.23 11.4 7.7 0.41 10.5 6.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) RR_TM4-6 PF06459.12 KIK64748.1 - 0.65 9.8 5.4 0.8 9.5 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KIK64748.1 - 3 6.5 7.6 3.7 6.2 7.3 1.3 1 1 0 1 1 1 0 Presenilin PRC2_HTH_1 PF18118.1 KIK64748.1 - 4.3 8.2 8.2 1.3e+02 3.4 7.6 2.3 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain WD40 PF00400.32 KIK64749.1 - 1.5e-21 76.3 15.7 4.5e-08 33.6 1.3 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64749.1 - 7.7e-10 38.9 0.0 0.0052 17.1 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK64749.1 - 0.003 16.6 0.1 3.6 6.5 0.0 3.1 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK64749.1 - 0.0079 16.1 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PQQ PF01011.21 KIK64749.1 - 0.061 13.3 0.3 55 3.9 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PD40 PF07676.12 KIK64749.1 - 0.17 11.8 2.7 5.2 7.1 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK64750.1 - 0.016 15.6 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 KIK64750.1 - 0.026 14.4 0.2 0.038 13.9 0.2 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK64750.1 - 0.038 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KIK64750.1 - 0.046 12.9 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIK64750.1 - 0.054 13.9 0.2 0.091 13.2 0.2 1.5 1 1 0 1 1 1 0 RNA helicase PhoH PF02562.16 KIK64750.1 - 0.077 12.4 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KIK64750.1 - 0.089 12.7 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KIK64750.1 - 0.09 12.9 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK64750.1 - 0.13 12.8 1.2 0.19 12.3 1.2 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK64750.1 - 0.15 12.1 0.6 0.27 11.3 0.6 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KIK64750.1 - 0.17 11.8 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.32 KIK64751.1 - 6.7e-24 83.7 26.0 1.3e-09 38.5 1.4 5.9 6 0 0 6 6 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64751.1 - 1.7e-10 41.1 0.1 0.0073 16.6 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK64751.1 - 4e-09 36.6 0.0 1.2e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KIK64751.1 - 0.00061 18.9 0.4 1.1 8.2 0.0 3.3 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK64751.1 - 0.00094 19.1 4.5 0.1 12.5 0.1 3.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK64751.1 - 0.002 18.5 0.0 0.0072 16.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain HHH_7 PF14635.6 KIK64751.1 - 0.0062 16.9 1.1 0.79 10.1 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif Nop PF01798.18 KIK64751.1 - 0.014 14.8 0.2 0.03 13.8 0.2 1.4 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Gmad1 PF10647.9 KIK64751.1 - 0.015 15.1 2.0 0.45 10.2 0.8 2.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.11 KIK64751.1 - 0.019 14.9 0.0 0.056 13.3 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A AAA_22 PF13401.6 KIK64751.1 - 0.032 14.5 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK64751.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 NTPase APS_kinase PF01583.20 KIK64751.1 - 0.092 12.6 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK64751.1 - 0.11 12.9 0.1 0.41 11.1 0.1 2.0 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KIK64751.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Peptidase_S9_N PF02897.15 KIK64751.1 - 0.14 11.0 0.1 14 4.3 0.0 2.8 1 1 2 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF3349 PF11829.8 KIK64751.1 - 1.1 10.1 2.8 1.2 10.0 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) WD40 PF00400.32 KIK64756.1 - 1.9e-132 427.3 74.0 9.5e-10 38.9 0.7 15.8 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK64756.1 - 2.1e-54 181.8 6.8 0.00073 19.8 0.0 14.3 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK64756.1 - 5.5e-23 80.3 13.1 3.6 7.6 0.0 13.2 13 0 0 13 13 13 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK64756.1 - 1e-12 47.7 2.3 4.6 6.1 0.0 9.8 3 3 6 10 10 10 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK64756.1 - 3.4e-09 36.8 0.0 6.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KIK64756.1 - 6.4e-08 32.3 0.0 13 5.0 0.0 8.1 8 3 1 10 10 10 0 WD40-like domain AAA PF00004.29 KIK64756.1 - 1.6e-06 28.6 0.0 5.4e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK64756.1 - 3.8e-06 27.4 0.0 8.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 KIK64756.1 - 2.3e-05 22.9 0.0 0.26 9.5 0.0 5.1 4 2 2 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz Pyr_redox_dim PF02852.22 KIK64756.1 - 0.004 17.4 0.0 21 5.4 0.0 4.9 4 2 3 7 7 6 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Proteasome_A_N PF10584.9 KIK64756.1 - 0.018 14.7 28.2 68 3.3 0.0 11.2 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature PQQ PF01011.21 KIK64756.1 - 0.022 14.7 0.4 1.2e+02 2.9 0.0 5.8 7 0 0 7 7 6 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK64756.1 - 0.05 14.1 10.4 69 4.1 0.0 7.6 5 3 5 10 10 10 0 PQQ-like domain PIF1 PF05970.14 KIK64756.1 - 0.1 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase CHASE9 PF17153.4 KIK64756.1 - 0.14 12.3 0.1 46 4.2 0.0 4.9 6 0 0 6 6 6 0 Periplasmic sensor domain, extracellular Mucin PF01456.17 KIK64757.1 - 0.027 14.5 9.0 0.047 13.7 9.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Lin-8 PF03353.15 KIK64757.1 - 2.2 7.8 9.4 0.54 9.8 2.9 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SSP160 PF06933.11 KIK64757.1 - 5.9 5.0 10.0 8.3 4.5 10.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Acyltransferase PF01553.21 KIK64758.1 - 4.7e-31 107.2 0.0 6.9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase GDPD PF03009.17 KIK64759.1 - 1.5e-32 113.3 0.0 2.4e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIK64759.1 - 5.1e-05 23.6 0.1 5.1e-05 23.6 0.1 2.5 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family PPK2 PF03976.14 KIK64759.1 - 0.041 13.4 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) adh_short PF00106.25 KIK64760.1 - 4.3e-20 72.0 0.0 7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64760.1 - 6.1e-11 42.3 0.0 8.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK64760.1 - 1.4e-07 31.6 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK64760.1 - 1.7e-05 24.1 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 KIK64760.1 - 0.025 15.1 0.0 0.059 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KIK64761.1 - 3.4e-21 75.6 0.0 4.4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK64761.1 - 1.7e-09 37.8 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK64761.1 - 2.2e-09 37.2 0.0 2.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KIK64761.1 - 0.00017 20.8 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK64762.1 - 4.4e-12 45.9 0.6 1.4e-09 37.7 0.4 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK64762.1 - 3.5e-07 30.3 0.1 5.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK64762.1 - 0.00012 21.7 0.5 0.21 11.1 0.3 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KIK64762.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Peptidase_C65 PF10275.9 KIK64765.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase C65 Otubain MFS_1 PF07690.16 KIK64767.1 - 4.6e-11 42.2 12.0 5.6e-11 41.9 12.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5127 PF17168.4 KIK64768.1 - 2.2e-79 266.4 6.9 4.6e-79 265.4 6.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK64768.1 - 2.7e-74 248.6 0.8 5.6e-74 247.5 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK64768.1 - 8e-51 172.8 5.7 4.5e-49 167.1 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK64768.1 - 1.3e-10 40.6 0.1 3.4e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) zf-MYND PF01753.18 KIK64770.1 - 1.9e-08 34.2 9.8 2.9e-08 33.6 9.8 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIK64770.1 - 0.036 14.1 4.2 0.073 13.2 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BPL_N PF09825.9 KIK64770.1 - 0.054 12.6 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal zf-C6H2 PF15801.5 KIK64770.1 - 0.071 13.4 5.0 0.11 12.8 5.0 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Podoplanin PF05808.11 KIK64771.1 - 0.00018 21.6 0.6 0.00033 20.8 0.6 1.4 1 0 0 1 1 1 1 Podoplanin DUF2207 PF09972.9 KIK64771.1 - 0.086 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sporozoite_P67 PF05642.11 KIK64771.1 - 0.75 7.8 8.4 1.1 7.3 8.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF498 PF04430.14 KIK64772.1 - 4.1e-30 104.0 0.0 5.7e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) RRP7 PF12923.7 KIK64776.1 - 3.5e-05 23.9 1.6 4.2e-05 23.7 1.6 1.1 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain INO80_Ies4 PF08193.11 KIK64778.1 - 1.4 8.8 9.6 0.085 12.8 4.3 1.6 2 0 0 2 2 2 0 INO80 complex subunit Ies4 Pkinase_Tyr PF07714.17 KIK64779.1 - 2.7e-36 125.2 0.0 3.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64779.1 - 7.2e-30 104.2 0.0 9e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KIK64780.1 - 5.1e-62 209.6 0.0 5.9e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64780.1 - 2e-41 142.0 0.0 2.4e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK64780.1 - 0.00017 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK64780.1 - 0.00064 19.1 0.1 0.0032 16.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like RRP7 PF12923.7 KIK64783.1 - 6.1e-28 97.3 9.2 6.1e-28 97.3 9.2 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KIK64783.1 - 1.1e-10 41.6 2.1 1.6e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KIK64783.1 - 0.023 14.5 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5093 PF17011.5 KIK64783.1 - 0.52 10.6 0.0 0.52 10.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) CPSF100_C PF13299.6 KIK64783.1 - 0.82 9.8 6.2 0.73 10.0 0.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RRM_1 PF00076.22 KIK64784.1 - 1.7e-30 104.7 0.0 5.7e-16 58.1 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK64784.1 - 4.9e-05 23.3 0.1 0.00015 21.7 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIK64784.1 - 0.00095 19.1 0.0 0.0035 17.3 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KIK64784.1 - 0.0092 15.6 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK64784.1 - 0.064 13.4 0.0 0.71 10.0 0.1 2.6 3 1 0 3 3 3 0 RNA recognition motif RasGAP PF00616.19 KIK64785.1 - 1.1e-20 74.3 0.0 1.6e-16 60.7 0.0 3.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KIK64785.1 - 8.8e-06 25.9 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Nucleopor_Nup85 PF07575.13 KIK64786.1 - 0.014 14.0 0.0 0.024 13.2 0.0 1.3 2 0 0 2 2 2 0 Nup85 Nucleoporin Antigen_Bd37 PF11641.8 KIK64787.1 - 0.058 12.9 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein KDZ PF18758.1 KIK64788.1 - 1.7e-16 60.5 0.2 3.1e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Pox_T4_C PF04490.12 KIK64788.1 - 0.0037 17.4 1.3 0.087 13.0 0.2 2.2 1 1 1 2 2 2 2 Poxvirus T4 protein, C terminus KDZ PF18758.1 KIK64789.1 - 1.9e-24 86.5 0.3 3.2e-24 85.8 0.3 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK64789.1 - 0.00067 19.8 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK64789.1 - 0.079 12.8 0.3 0.52 10.2 0.0 2.3 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases zf-TFIIB PF13453.6 KIK64789.1 - 0.093 12.1 1.5 1.7 8.1 0.1 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger Cauli_VI PF01693.16 KIK64791.1 - 0.00066 19.9 2.1 0.83 10.0 0.4 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin DUF2353 PF09789.9 KIK64794.1 - 1.9 7.8 23.9 2.9 7.2 9.2 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) FapA PF03961.13 KIK64794.1 - 5.1 5.6 11.8 3.3 6.2 6.8 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Peptidase_S46 PF10459.9 KIK64794.1 - 7.6 5.0 11.6 11 4.4 11.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Sulfotransfer_3 PF13469.6 KIK64795.1 - 0.019 15.4 1.7 6.8 7.0 0.1 2.8 3 1 1 4 4 4 0 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK64796.1 - 0.0017 18.8 0.0 0.0083 16.5 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK64797.1 - 0.0021 18.5 0.0 0.0024 18.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK64798.1 - 0.059 13.7 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK64799.1 - 0.001 19.5 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Phage_AlpA PF05930.12 KIK64799.1 - 0.11 12.3 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Sulfotransfer_3 PF13469.6 KIK64800.1 - 0.024 15.0 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK64801.1 - 0.00054 20.4 0.0 0.0025 18.3 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIK64801.1 - 0.043 13.3 0.0 0.068 12.6 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain NADH_dh_m_C1 PF15088.6 KIK64801.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Sulfotransfer_3 PF13469.6 KIK64802.1 - 0.00018 22.0 0.0 0.00086 19.7 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIK64802.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain PhaP_Bmeg PF09602.10 KIK64802.1 - 0.01 15.8 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) G10 PF01125.17 KIK64803.1 - 2.9e-68 228.2 7.9 3.3e-68 228.1 7.9 1.0 1 0 0 1 1 1 1 G10 protein Na_H_Exchanger PF00999.21 KIK64804.1 - 9.3e-49 166.2 52.1 1.3e-48 165.7 52.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Band_7 PF01145.25 KIK64806.1 - 2.7e-23 82.9 4.3 4.1e-23 82.3 4.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family RasGAP PF00616.19 KIK64809.1 - 1.5e-15 57.5 5.2 1.6e-14 54.1 0.0 3.6 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KIK64809.1 - 2.8e-06 27.5 0.1 1.6e-05 25.1 0.1 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain ADH_N PF08240.12 KIK64811.1 - 1.6e-21 76.2 2.4 1.6e-21 76.2 2.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK64811.1 - 1.6e-09 37.8 0.0 3.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK64811.1 - 0.00011 21.7 0.1 0.00018 20.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIK64811.1 - 0.0025 18.0 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KIK64811.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIK64811.1 - 0.098 12.0 0.7 0.18 11.1 0.3 1.5 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 KIK64811.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KIK64811.1 - 0.21 11.0 0.2 1.2 8.5 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase NADH_4Fe-4S PF10589.9 KIK64811.1 - 0.38 10.8 5.6 1.1 9.4 5.6 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region MoCF_biosynth PF00994.24 KIK64812.1 - 9.2e-50 168.0 0.4 1.3e-24 86.5 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KIK64812.1 - 1.8e-32 112.3 0.0 3e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KIK64812.1 - 2.1e-15 56.6 0.1 4.1e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Abhydrolase_1 PF00561.20 KIK64813.1 - 2.3e-05 24.2 0.1 0.00011 22.0 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK64813.1 - 0.0019 17.5 0.0 0.0087 15.3 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EVE PF01878.18 KIK64814.1 - 5.1e-42 143.3 0.1 1.5e-40 138.5 0.1 2.4 1 1 0 1 1 1 1 EVE domain SH3_1 PF00018.28 KIK64815.1 - 1.6e-05 24.4 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK64815.1 - 0.00037 20.1 0.1 0.00069 19.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK64815.1 - 0.0093 15.8 1.1 0.0093 15.8 1.1 2.0 2 1 0 2 2 2 1 Variant SH3 domain Peptidase_S49_N PF08496.10 KIK64815.1 - 2.6 8.1 4.4 4.7 7.3 4.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4337 PF14235.6 KIK64815.1 - 2.8 8.0 9.3 6.6 6.8 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Barwin PF00967.17 KIK64820.1 - 0.019 14.8 0.2 0.023 14.6 0.2 1.2 1 0 0 1 1 1 0 Barwin family NAD4L PF06235.11 KIK64822.1 - 0.00076 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 NADH dehydrogenase subunit 4L (NAD4L) MSA-2c PF12238.8 KIK64823.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c NAD4L PF06235.11 KIK64826.1 - 0.027 14.4 2.0 0.041 13.9 0.1 2.2 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) F-box-like PF12937.7 KIK64833.1 - 3.7e-07 29.9 3.0 6.3e-07 29.2 0.7 2.7 2 0 0 2 2 2 1 F-box-like Phage_XkdX PF09693.10 KIK64834.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) TEX13 PF15186.6 KIK64834.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family F-box-like PF12937.7 KIK64835.1 - 3.3e-07 30.1 0.5 3.3e-07 30.1 0.5 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK64835.1 - 0.00065 19.5 8.4 0.0077 16.1 0.2 3.4 3 0 0 3 3 3 2 F-box domain Questin_oxidase PF14027.6 KIK64836.1 - 8.5e-83 278.7 0.0 9.9e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 KIK64837.1 - 1.1e-35 123.7 0.1 1.5e-35 123.4 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like DIT1_PvcA PF05141.12 KIK64837.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein BBE PF08031.12 KIK64838.1 - 1.8e-11 43.9 0.1 3.7e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KIK64838.1 - 1e-05 25.3 1.6 1.9e-05 24.4 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain MKRN1_C PF15815.5 KIK64838.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal Questin_oxidase PF14027.6 KIK64839.1 - 6.3e-86 289.0 0.0 7.4e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like F-box-like PF12937.7 KIK64840.1 - 9e-13 47.9 1.6 5.9e-12 45.3 0.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK64840.1 - 3e-05 23.8 0.1 0.00011 21.9 0.1 2.1 1 0 0 1 1 1 1 F-box domain Peptidase_S10 PF00450.22 KIK64841.1 - 9.5e-100 334.9 0.0 1.2e-99 334.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Stevor PF17410.2 KIK64841.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 KIK64841.1 - 0.93 8.9 6.5 1.8 8.1 6.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Thioredoxin_4 PF13462.6 KIK64845.1 - 2.8e-10 40.6 0.0 6.8e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KIK64845.1 - 0.15 11.9 0.1 0.5 10.1 0.1 1.9 2 1 0 2 2 2 0 DSBA-like thioredoxin domain PCI PF01399.27 KIK64846.1 - 5e-12 46.3 0.0 1.2e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain NAD_binding_10 PF13460.6 KIK64847.1 - 3.5e-11 43.3 0.0 0.00018 21.4 0.0 2.5 2 1 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KIK64847.1 - 2.2e-05 24.0 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK64847.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KIK64847.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Kringle PF00051.18 KIK64851.1 - 0.045 14.1 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 Kringle domain HTH_Tnp_1 PF01527.20 KIK64852.1 - 0.14 12.5 0.1 0.57 10.5 0.1 1.9 2 0 0 2 2 2 0 Transposase Pkinase_Tyr PF07714.17 KIK64853.1 - 1.3e-38 132.8 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64853.1 - 5.1e-30 104.7 0.0 8.8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FPP PF05911.11 KIK64853.1 - 0.012 13.9 0.0 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DLIC PF05783.11 KIK64853.1 - 1.4 7.7 4.6 2.2 7.0 4.6 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Amidohydro_1 PF01979.20 KIK64854.1 - 9.5e-14 51.4 0.0 9.3e-13 48.2 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK64854.1 - 3.5e-13 49.8 0.5 9e-09 35.3 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family DmpG_comm PF07836.11 KIK64854.1 - 0.029 13.9 0.0 0.46 10.0 0.0 2.6 2 0 0 2 2 2 0 DmpG-like communication domain Pkinase_Tyr PF07714.17 KIK64855.1 - 1.7e-06 27.5 0.0 2e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64855.1 - 0.0004 19.8 0.0 0.0004 19.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64858.1 - 2.5e-26 92.5 0.0 3.1e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64858.1 - 1.6e-21 76.8 0.0 2.1e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3140 PF11338.8 KIK64858.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Amidohydro_3 PF07969.11 KIK64860.1 - 2.6e-13 50.2 0.2 7.7e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK64860.1 - 1e-12 48.1 0.2 3.3e-11 43.1 0.0 2.9 2 1 0 2 2 2 1 Amidohydrolase family DmpG_comm PF07836.11 KIK64860.1 - 0.037 13.6 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 DmpG-like communication domain Peptidase_M75 PF09375.10 KIK64860.1 - 0.056 12.9 0.2 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Imelysin Pkinase_Tyr PF07714.17 KIK64861.1 - 5e-29 101.4 0.0 6.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64861.1 - 9.3e-28 97.3 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK64861.1 - 0.00013 21.6 0.0 0.075 12.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 KIK64861.1 - 0.0018 17.2 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK64861.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK64864.1 - 6.1e-40 137.1 0.0 8.1e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64864.1 - 8.1e-34 117.2 0.0 1.8e-33 116.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64865.1 - 1.5e-40 139.1 0.0 2.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64865.1 - 5.9e-32 111.1 0.0 1.1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64866.1 - 1.8e-27 96.3 0.0 2e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64866.1 - 1.3e-23 83.7 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK64866.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK64867.1 - 5.4e-06 25.9 0.0 6.4e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64867.1 - 0.00052 19.4 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain BTB PF00651.31 KIK64868.1 - 8.8e-08 32.4 0.1 2.3e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain RasGAP PF00616.19 KIK64870.1 - 9.4e-24 84.3 0.1 1.4e-15 57.6 0.0 3.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KIK64870.1 - 0.0012 19.0 0.1 0.0037 17.4 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FAD_binding_3 PF01494.19 KIK64871.1 - 2.1e-14 53.5 0.4 9e-10 38.3 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK64871.1 - 0.0011 18.2 0.1 0.65 9.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK64871.1 - 0.0067 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DASH_Spc19 PF08287.11 KIK64872.1 - 7.8e-25 87.6 12.1 1e-23 84.0 12.0 1.9 1 1 0 1 1 1 1 Spc19 SATase_N PF06426.14 KIK64872.1 - 0.0059 17.0 0.3 0.013 15.9 0.1 1.6 1 1 1 2 2 2 1 Serine acetyltransferase, N-terminal NuA4 PF09340.10 KIK64872.1 - 0.038 13.9 0.4 0.038 13.9 0.4 2.3 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Prefoldin_2 PF01920.20 KIK64872.1 - 0.046 13.7 12.1 0.37 10.8 2.6 2.6 1 1 1 2 2 2 0 Prefoldin subunit Exotox-A_target PF09102.10 KIK64872.1 - 0.064 13.3 0.6 0.76 9.8 0.0 2.2 1 1 1 2 2 2 0 Exotoxin A, targeting DUF2968 PF11180.8 KIK64872.1 - 0.18 11.4 8.7 0.25 11.0 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Troponin PF00992.20 KIK64872.1 - 0.49 10.7 10.0 0.31 11.3 8.1 1.6 2 0 0 2 2 2 0 Troponin Seryl_tRNA_N PF02403.22 KIK64872.1 - 0.6 10.4 7.3 0.69 10.2 6.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Uso1_p115_C PF04871.13 KIK64872.1 - 0.92 9.9 11.3 0.87 10.0 10.1 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lzipper-MIP1 PF14389.6 KIK64872.1 - 0.96 9.8 13.0 1.8 8.9 7.9 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.6 KIK64872.1 - 1.4 9.4 11.8 3.9 8.0 1.6 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.6 KIK64872.1 - 1.7 8.0 13.0 1.8 7.9 3.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5595 PF18077.1 KIK64872.1 - 6.1 7.0 7.2 1.9 8.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) PspB PF06667.12 KIK64872.1 - 6.2 7.0 6.8 2.3 8.3 1.8 2.3 2 0 0 2 2 2 0 Phage shock protein B Val_tRNA-synt_C PF10458.9 KIK64872.1 - 7.1 7.0 12.4 9.7 6.6 2.2 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm NAM-associated PF14303.6 KIK64873.1 - 0.042 14.6 0.4 0.042 14.6 0.4 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF1180 PF06679.12 KIK64873.1 - 4.3 7.7 6.7 16 5.8 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkinase_Tyr PF07714.17 KIK64874.1 - 1.8e-37 129.1 0.0 2.4e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK64874.1 - 9e-32 110.5 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 KIK64874.1 - 8.5e-08 32.2 14.8 1.6e-07 31.4 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 KIK64875.1 - 1.8e-14 53.8 1.1 3.4e-14 52.9 1.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_trans PF04082.18 KIK64877.1 - 1.4e-08 34.2 1.1 2.1e-08 33.5 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KIK64878.1 - 5.7e-70 236.4 0.0 1.3e-69 235.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Nop14 PF04147.12 KIK64879.1 - 1.5 7.0 10.7 1.3 7.1 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF745 PF05335.13 KIK64881.1 - 0.042 13.6 2.6 3.7 7.2 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) BAR_2 PF10455.9 KIK64881.1 - 0.048 12.8 0.6 0.085 12.0 0.6 1.6 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF648 PF04890.13 KIK64881.1 - 0.092 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) PKcGMP_CC PF16808.5 KIK64881.1 - 0.44 10.4 5.0 3.3 7.7 0.6 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4201 PF13870.6 KIK64882.1 - 0.0045 16.7 2.7 0.0087 15.8 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) APG6_N PF17675.1 KIK64882.1 - 0.0071 16.9 2.6 0.0071 16.9 2.6 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region Peptidase_S49_N PF08496.10 KIK64882.1 - 0.008 16.2 0.5 0.015 15.4 0.5 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF3450 PF11932.8 KIK64882.1 - 0.011 15.1 3.2 0.011 15.1 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF885 PF05960.11 KIK64882.1 - 0.032 13.9 0.1 0.071 12.8 0.2 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) FAM76 PF16046.5 KIK64882.1 - 0.18 11.2 3.7 0.038 13.3 0.5 1.5 2 0 0 2 2 2 0 FAM76 protein Sec2p PF06428.11 KIK64882.1 - 0.19 11.7 7.0 0.043 13.8 2.8 2.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fez1 PF06818.15 KIK64882.1 - 0.43 11.0 8.9 0.042 14.3 3.9 1.8 2 0 0 2 2 2 0 Fez1 AAA_23 PF13476.6 KIK64882.1 - 1.9 9.0 6.5 2.2 8.7 6.5 1.4 1 1 0 1 1 1 0 AAA domain CENP-H PF05837.12 KIK64882.1 - 2.2 8.7 7.6 0.27 11.7 3.1 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 KIK64882.1 - 7.3 6.8 7.2 1.4 9.1 0.7 2.6 2 1 0 2 2 2 0 Basic region leucine zipper S-antigen PF05756.11 KIK64884.1 - 0.21 12.0 3.0 2.7 8.4 0.1 2.2 2 0 0 2 2 2 0 S-antigen protein BLOC1S3 PF15753.5 KIK64884.1 - 5.4 7.1 6.1 2.3 8.3 1.9 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 RPA43_OB PF17875.1 KIK64885.1 - 0.28 11.8 3.9 0.2 12.3 1.3 1.8 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4824 PF16106.5 KIK64888.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) adh_short_C2 PF13561.6 KIK64890.1 - 2.5e-59 200.7 1.8 3e-59 200.4 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK64890.1 - 5.3e-44 150.0 1.9 6.4e-44 149.8 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK64890.1 - 4.1e-08 33.3 1.8 6.9e-08 32.6 1.8 1.3 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK64890.1 - 0.02 14.2 0.2 0.04 13.2 0.2 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flavodoxin_1 PF00258.25 KIK64890.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin LRR_4 PF12799.7 KIK64892.1 - 0.08 13.4 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) AMP-binding PF00501.28 KIK64898.1 - 4.2e-12 45.4 0.0 6.5e-07 28.3 0.0 2.7 3 0 0 3 3 3 2 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK64898.1 - 2.5e-08 33.4 0.0 4.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK64898.1 - 0.00025 20.6 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK64898.1 - 0.014 15.7 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KIK64899.1 - 2.5e-59 200.7 1.8 3e-59 200.4 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK64899.1 - 5.3e-44 150.0 1.9 6.4e-44 149.8 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK64899.1 - 4.1e-08 33.3 1.8 6.9e-08 32.6 1.8 1.3 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK64899.1 - 0.02 14.2 0.2 0.04 13.2 0.2 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flavodoxin_1 PF00258.25 KIK64899.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin KDZ PF18758.1 KIK64900.1 - 5.3e-42 143.9 0.1 6.5e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK64901.1 - 2.6e-25 88.7 3.3 3.3e-25 88.3 3.3 1.1 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK64901.1 - 0.0035 17.5 2.7 0.0048 17.0 2.7 1.2 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Chromo PF00385.24 KIK64903.1 - 0.2 11.6 1.2 31 4.6 0.0 3.3 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Cauli_VI PF01693.16 KIK64905.1 - 5.4e-07 29.8 0.0 8.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Imm30 PF15565.6 KIK64906.1 - 0.094 12.8 0.1 0.4 10.8 0.1 2.1 1 0 0 1 1 1 0 Immunity protein 30 NPV_P10 PF05531.12 KIK64906.1 - 7.7 7.1 11.9 7.7 7.1 2.3 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PI3K_1B_p101 PF10486.9 KIK64908.1 - 1.6 6.4 10.7 2.6 5.7 10.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 KIK64908.1 - 9.8 5.7 53.9 48 3.5 1.2 3.5 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 KIK64909.1 - 0.098 11.2 24.4 0.13 10.8 24.4 1.1 1 0 0 1 1 1 0 Macoilin family HEAT_EZ PF13513.6 KIK64912.1 - 1.9e-18 66.6 11.6 2.7e-11 43.7 0.0 8.4 10 0 0 10 10 8 2 HEAT-like repeat HEAT PF02985.22 KIK64912.1 - 9.8e-17 59.6 11.4 2.2e-05 24.3 0.0 10.8 13 0 0 13 13 13 2 HEAT repeat HEAT_2 PF13646.6 KIK64912.1 - 1.6e-13 50.8 7.0 0.0013 19.1 0.0 7.7 6 2 3 9 9 8 5 HEAT repeats IBN_N PF03810.19 KIK64912.1 - 4e-11 42.7 0.9 2.1e-09 37.1 0.1 3.8 5 0 0 5 5 5 1 Importin-beta N-terminal domain Arm PF00514.23 KIK64912.1 - 4.5e-07 29.7 7.1 0.008 16.2 0.0 6.5 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KIK64912.1 - 6.4e-05 23.1 0.2 0.071 13.1 0.0 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KIK64912.1 - 0.00038 19.7 0.4 1.2 8.2 0.0 3.6 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KIK64912.1 - 0.00077 19.4 1.5 0.98 9.3 0.2 4.6 3 2 2 5 5 4 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KIK64912.1 - 0.0026 16.1 0.2 0.91 7.7 0.1 3.4 2 1 1 3 3 3 1 Down-regulated in metastasis CLASP_N PF12348.8 KIK64912.1 - 0.0077 15.8 0.3 10 5.6 0.1 4.5 3 2 3 6 6 6 1 CLASP N terminal RIX1 PF08167.12 KIK64912.1 - 0.029 14.1 0.2 12 5.6 0.0 4.1 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis TIP120 PF08623.10 KIK64912.1 - 0.03 14.1 0.3 0.81 9.4 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Proteasom_PSMB PF10508.9 KIK64912.1 - 0.061 11.8 0.1 0.24 9.9 0.1 1.9 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 KIK64912.1 - 0.066 11.8 1.1 11 4.5 0.0 3.4 2 1 0 2 2 2 0 Adaptin N terminal region IFRD PF05004.13 KIK64912.1 - 0.069 12.2 3.2 1.7 7.7 0.0 3.6 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) Phasin_2 PF09361.10 KIK64912.1 - 1.4 9.2 4.5 4 7.8 0.0 3.2 3 0 0 3 3 3 0 Phasin protein LSM PF01423.22 KIK64913.1 - 2.2e-20 72.1 0.0 2.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KIK64913.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Ribosomal_L4 PF00573.22 KIK64913.1 - 0.88 9.2 2.3 0.88 9.2 2.3 1.2 1 1 0 1 1 1 0 Ribosomal protein L4/L1 family PAP_assoc PF03828.19 KIK64914.1 - 7.6e-15 54.9 0.1 1.5e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIK64914.1 - 2.9e-05 24.2 0.0 7.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIK64914.1 - 0.033 14.2 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Yae1_N PF09811.9 KIK64915.1 - 7.5e-11 41.5 0.6 1.3e-10 40.8 0.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MtrG PF04210.13 KIK64915.1 - 0.033 14.0 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Amidohydro_3 PF07969.11 KIK64916.1 - 1.4e-86 291.9 0.1 1.7e-86 291.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIK64916.1 - 3.8e-11 42.9 0.0 2.4e-08 33.7 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Sugar_tr PF00083.24 KIK64919.1 - 1.9e-94 317.1 27.3 2.2e-94 316.9 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK64919.1 - 1.9e-26 92.8 23.4 1.9e-26 92.8 23.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK64919.1 - 0.0011 17.5 9.4 0.0013 17.2 1.3 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) HpcH_HpaI PF03328.14 KIK64920.1 - 1e-28 100.0 0.1 1.2e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PfkB PF00294.24 KIK64921.1 - 7.5e-26 91.1 0.1 2.3e-25 89.5 0.1 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mrr_N PF14338.6 KIK64921.1 - 0.00097 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Mrr N-terminal domain Rap_GAP PF02145.15 KIK64922.1 - 1.2e-46 158.6 0.0 2.1e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KIK64922.1 - 1.6e-39 136.0 3.4 1.7e-36 126.1 2.0 2.9 2 1 0 2 2 2 2 Tuberin Membr_traf_MHD PF10540.9 KIK64923.1 - 1.4e-26 93.5 0.0 2e-23 83.2 0.0 3.4 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KIK64923.1 - 1.9e-10 41.0 0.0 5.6e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Imm53 PF15580.6 KIK64923.1 - 0.15 11.8 0.1 0.43 10.3 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 53 DUF3384 PF11864.8 KIK64924.1 - 1.1e-08 34.5 0.0 8.7e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) ClpB_D2-small PF10431.9 KIK64924.1 - 0.032 14.3 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein DUF3285 PF11688.8 KIK64925.1 - 1.9 8.5 5.2 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) HSP70 PF00012.20 KIK64926.1 - 8.7e-83 278.5 2.2 8.7e-83 278.5 2.2 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIK64926.1 - 0.0019 17.1 0.1 0.0038 16.1 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Phage_tail_APC PF16778.5 KIK64926.1 - 0.02 14.7 1.8 0.52 10.2 0.7 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein PAP1 PF08601.10 KIK64926.1 - 3.3 7.3 21.9 4 7.1 9.3 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 HMG_box PF00505.19 KIK64928.1 - 6.8e-24 84.1 1.9 1.2e-23 83.3 1.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK64928.1 - 5.3e-18 65.4 3.0 8.2e-18 64.8 3.0 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KIK64928.1 - 0.0015 18.4 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 KIK64928.1 - 0.0072 16.9 0.4 0.012 16.2 0.2 1.4 1 1 0 1 1 1 1 YABBY protein RR_TM4-6 PF06459.12 KIK64928.1 - 2.2 8.1 4.8 2.9 7.6 4.8 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0242 PF06785.11 KIK64929.1 - 0.35 11.0 1.9 0.28 11.3 0.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3290 PF11694.8 KIK64930.1 - 0.29 11.1 0.4 0.41 10.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF4131 PF13567.6 KIK64930.1 - 0.53 9.9 3.1 0.87 9.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Gpr1_Fun34_YaaH PF01184.19 KIK64931.1 - 6.7e-28 97.7 16.9 8.4e-28 97.4 16.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Methyltransf_23 PF13489.6 KIK64932.1 - 1.1e-09 38.4 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK64932.1 - 6.6e-08 33.1 0.0 1.6e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK64932.1 - 0.00036 19.9 0.0 0.0012 18.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK64932.1 - 0.00037 21.1 0.0 0.0008 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK64932.1 - 0.00072 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PseudoU_synth_1 PF01416.20 KIK64933.1 - 6.1e-22 78.1 0.0 2.6e-21 76.1 0.0 2.1 2 1 0 2 2 2 1 tRNA pseudouridine synthase Piwi PF02171.17 KIK64934.1 - 1.8e-82 277.0 0.0 2.4e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK64934.1 - 1.1e-22 81.1 0.0 2.6e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIK64934.1 - 4.1e-20 71.2 0.2 4.8e-19 67.8 0.3 2.5 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KIK64934.1 - 5.6e-17 61.8 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KIK64934.1 - 1.7e-12 47.5 0.0 4.6e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK64934.1 - 0.0023 18.2 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute SMP PF04927.12 KIK64935.1 - 0.035 14.6 17.3 0.038 14.5 0.3 4.4 4 1 0 4 4 4 0 Seed maturation protein Fungal_trans PF04082.18 KIK64937.1 - 4.3e-27 94.8 1.3 7.6e-27 94.0 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Interferon PF00143.19 KIK64937.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain SurE PF01975.17 KIK64938.1 - 6.8e-36 123.9 0.5 9.4e-36 123.4 0.5 1.1 1 0 0 1 1 1 1 Survival protein SurE SurE PF01975.17 KIK64939.1 - 5e-36 124.3 0.2 6.7e-36 123.9 0.2 1.1 1 0 0 1 1 1 1 Survival protein SurE Trypan_PARP PF05887.11 KIK64939.1 - 0.012 15.6 1.6 0.012 15.6 1.6 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SurE PF01975.17 KIK64940.1 - 2.1e-32 112.5 0.1 3e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE SurE PF01975.17 KIK64941.1 - 1.2e-27 96.9 0.1 8e-26 91.0 0.1 2.1 1 1 0 1 1 1 1 Survival protein SurE SurE PF01975.17 KIK64942.1 - 9.6e-31 107.1 0.7 1.4e-30 106.6 0.7 1.2 1 0 0 1 1 1 1 Survival protein SurE ADH_zinc_N PF00107.26 KIK64943.1 - 2.6e-27 95.4 1.0 4.4e-27 94.6 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK64943.1 - 2.5e-23 82.0 8.4 5.6e-23 80.9 8.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK64943.1 - 2e-09 38.6 0.2 3e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIK64943.1 - 0.011 15.3 0.1 0.027 13.9 0.1 1.7 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.7 KIK64944.1 - 0.14 12.1 8.1 14 5.7 6.5 3.3 2 1 0 2 2 2 0 F-box-like F-box-like PF12937.7 KIK64947.1 - 8.6e-06 25.6 0.5 4.1e-05 23.4 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK64947.1 - 0.013 15.4 1.7 0.044 13.7 0.3 2.7 2 1 0 2 2 2 0 F-box domain Pkinase PF00069.25 KIK64949.1 - 3.3e-07 29.9 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK64949.1 - 2.5e-06 27.0 0.6 3.9e-06 26.4 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK64949.1 - 1.6e-05 25.0 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK64949.1 - 2.8e-05 23.8 0.1 5.1e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK64949.1 - 3.2e-05 23.6 0.1 9.8e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KIK64949.1 - 0.0003 19.8 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK64949.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KIK64949.1 - 0.049 12.9 0.1 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Bromo_TP PF07524.13 KIK64949.1 - 0.093 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Pro_isomerase PF00160.21 KIK64950.1 - 5.6e-36 124.2 0.0 8.2e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIK64950.1 - 7.7e-16 57.7 0.0 1.4e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SSF PF00474.17 KIK64951.1 - 1.4e-13 50.5 21.5 2.2e-13 49.9 21.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Glyco_hydro_30 PF02055.16 KIK64952.1 - 1.2e-28 100.1 0.8 1.5e-28 99.8 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIK64952.1 - 5.4e-15 55.4 0.1 9.4e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KIK64952.1 - 0.0046 16.6 0.0 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Adaptin_N PF01602.20 KIK64953.1 - 6.8e-141 470.4 4.1 8.5e-141 470.1 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK64953.1 - 6.2e-59 198.7 2.7 7.6e-58 195.1 0.6 2.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK64953.1 - 1.1e-16 61.0 4.1 1.4e-06 28.5 0.0 6.3 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.22 KIK64953.1 - 3e-10 39.4 6.0 0.00014 21.8 0.1 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KIK64953.1 - 6.8e-06 26.5 4.2 7.6 7.2 0.0 6.7 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 KIK64953.1 - 0.0015 18.2 0.1 0.32 10.5 0.0 3.1 2 1 1 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 KIK64953.1 - 0.003 17.7 2.1 1.2 9.4 0.0 4.2 2 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KIK64953.1 - 0.0082 16.2 5.4 5.3 7.2 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KIK64953.1 - 0.016 15.1 0.6 0.17 11.8 0.1 2.6 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3949 PF13133.6 KIK64954.1 - 0.09 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) Complex1_LYR PF05347.15 KIK64955.1 - 1.8e-14 53.5 0.7 2.3e-14 53.1 0.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Asp PF00026.23 KIK64956.1 - 2.4e-44 152.0 0.0 3.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK64956.1 - 2.4e-06 27.9 2.7 3e-05 24.3 2.7 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK64956.1 - 0.0095 16.6 0.8 8.5 7.1 0.3 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KIK64956.1 - 0.064 13.0 0.0 2.5 7.9 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal MFS_1 PF07690.16 KIK64957.1 - 9.9e-37 126.7 49.2 1.1e-35 123.3 49.2 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KIK64957.1 - 0.0026 16.1 0.8 0.0026 16.1 0.8 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Pox_A14 PF05767.12 KIK64957.1 - 0.015 15.4 0.1 0.075 13.2 0.1 2.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 PDH PF02153.17 KIK64959.1 - 7.2e-15 54.7 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KIK64959.1 - 1.5e-06 28.4 0.1 3.3e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK64959.1 - 6.2e-06 26.7 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIK64959.1 - 4.5e-05 23.5 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIK64959.1 - 0.00015 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KIK64959.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KIK64959.1 - 0.005 16.2 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIK64959.1 - 0.0071 16.3 0.1 0.022 14.7 0.0 1.8 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KIK64959.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KIK64959.1 - 0.022 14.7 0.1 0.073 13.0 0.1 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KIK64959.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PglD_N PF17836.1 KIK64959.1 - 0.1 13.2 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain NACHT PF05729.12 KIK64960.1 - 0.017 15.0 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain YmzC PF14157.6 KIK64960.1 - 0.059 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 YmzC-like protein F-box-like PF12937.7 KIK64961.1 - 0.0039 17.0 4.1 0.12 12.3 1.6 3.2 2 1 1 3 3 3 2 F-box-like 4HBT PF03061.22 KIK64962.1 - 8.7e-05 22.8 0.1 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Cg6151-P PF10233.9 KIK64965.1 - 0.041 14.2 0.9 0.088 13.1 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF2339 PF10101.9 KIK64966.1 - 0.049 12.2 5.2 0.055 12.1 1.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) UPF0561 PF10573.9 KIK64966.1 - 0.064 13.4 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 HRG PF16954.5 KIK64966.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.5 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene SUI1 PF01253.22 KIK64967.1 - 3.8e-15 56.2 0.0 6.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2187 PF09953.9 KIK64967.1 - 0.031 14.3 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) CRM1_repeat_2 PF18784.1 KIK64967.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 DUF2339 PF10101.9 KIK64968.1 - 0.017 13.7 5.9 0.069 11.7 1.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2339) HRG PF16954.5 KIK64968.1 - 0.25 11.8 0.1 0.25 11.8 0.1 3.3 4 1 1 5 5 5 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene SUI1 PF01253.22 KIK64969.1 - 1.3e-16 60.8 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KIK64969.1 - 4.4e-12 46.5 0.3 1.4e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 KIK64969.1 - 0.0014 18.6 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 KIK64969.1 - 0.0029 17.5 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain RrnaAD PF00398.20 KIK64970.1 - 3.5e-59 200.0 0.0 4.4e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIK64970.1 - 1.9e-07 31.7 0.0 3.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK64970.1 - 1.2e-05 25.9 0.0 3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK64970.1 - 2.5e-05 24.1 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KIK64970.1 - 7.7e-05 22.1 0.0 0.00017 21.0 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIK64970.1 - 0.00027 20.8 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK64970.1 - 0.00046 20.9 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK64970.1 - 0.00072 19.1 0.1 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KIK64970.1 - 0.002 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KIK64970.1 - 0.0089 15.8 0.0 0.018 14.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 KIK64970.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 KIK64970.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KIK64970.1 - 0.052 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KIK64970.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DOT1 PF08123.13 KIK64970.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.16 KIK64970.1 - 0.1 12.3 0.1 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_32 PF13679.6 KIK64970.1 - 0.14 12.1 0.0 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF402 PF04167.13 KIK64971.1 - 0.04 14.1 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF402) APH PF01636.23 KIK64973.1 - 3.4e-11 43.5 0.1 5.5e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIK64973.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) F-box PF00646.33 KIK64974.1 - 0.46 10.4 7.9 19 5.3 7.9 2.9 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIK64974.1 - 5 7.1 7.7 7.6 6.5 4.4 2.7 2 1 0 2 2 2 0 F-box-like SPX PF03105.19 KIK64975.1 - 3.9 7.3 22.7 49 3.7 22.7 2.0 1 1 0 1 1 1 0 SPX domain Acetyltransf_1 PF00583.25 KIK64977.1 - 8.2e-10 38.9 0.2 1.2e-09 38.5 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK64977.1 - 3.5e-09 36.7 0.1 1.5e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK64977.1 - 5.2e-08 33.2 0.0 7.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK64977.1 - 4e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIK64977.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain tRNA-synt_1b PF00579.25 KIK64980.1 - 2.2e-72 243.9 0.0 2.9e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CK2S PF15011.6 KIK64980.1 - 0.0028 17.6 0.4 0.0068 16.3 0.4 1.7 1 0 0 1 1 1 1 Casein Kinase 2 substrate DUF4047 PF13256.6 KIK64980.1 - 0.19 11.9 0.6 0.51 10.5 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF1289 PF06945.13 KIK64983.1 - 0.042 13.7 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) p450 PF00067.22 KIK64984.1 - 8.8e-63 212.6 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 KIK64985.1 - 5.4e-127 425.0 43.2 7.3e-127 424.6 43.2 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Eclosion PF04736.12 KIK64985.1 - 0.083 12.6 0.7 0.21 11.3 0.7 1.6 1 0 0 1 1 1 0 Eclosion hormone IATP PF04568.12 KIK64986.1 - 5.2e-05 23.6 1.1 5.5e-05 23.5 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YgaB PF14182.6 KIK64986.1 - 0.047 14.1 2.1 0.065 13.6 2.1 1.2 1 0 0 1 1 1 0 YgaB-like protein ATP_sub_h PF10775.9 KIK64987.1 - 4.6e-26 90.6 1.9 8.3e-26 89.8 1.9 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h RNA_pol PF00940.19 KIK64988.1 - 1.4e-181 603.8 0.1 2e-181 603.4 0.1 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KIK64988.1 - 5.8e-95 318.5 0.0 5.8e-95 318.5 0.0 2.6 3 0 0 3 3 3 1 DNA-directed RNA polymerase N-terminal Ribosomal_60s PF00428.19 KIK64988.1 - 0.17 12.5 8.8 0.55 10.8 8.8 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.16 KIK64990.1 - 1.3e-39 136.1 36.5 1.3e-39 136.1 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK64990.1 - 1.4e-06 27.9 7.9 1.4e-06 27.9 7.9 2.6 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KIK64990.1 - 0.0061 15.5 26.5 0.051 12.4 26.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3624 PF12292.8 KIK64990.1 - 0.064 13.7 2.1 0.18 12.2 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) SUR7 PF06687.12 KIK64991.1 - 1.1e-14 54.6 19.0 2.6e-14 53.4 18.5 1.8 1 1 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KIK64991.1 - 0.049 13.4 0.5 0.073 12.9 0.5 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cad PF03596.13 KIK64991.1 - 0.082 12.8 3.1 0.16 11.8 3.1 1.5 1 0 0 1 1 1 0 Cadmium resistance transporter SRTM1 PF15872.5 KIK64991.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 p450 PF00067.22 KIK64992.1 - 1.6e-56 192.0 0.0 2.4e-41 141.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Pkinase PF00069.25 KIK64998.1 - 7.2e-23 81.3 0.0 8.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK64998.1 - 1.7e-13 50.5 0.0 1.9e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK64998.1 - 0.0006 19.8 0.6 0.0012 18.8 0.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK64998.1 - 0.0047 16.6 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK64998.1 - 0.067 12.5 0.1 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIK64998.1 - 0.076 12.6 0.2 0.097 12.2 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KIK65001.1 - 1.9e-71 240.5 0.0 2.7e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65001.1 - 8.4e-38 130.1 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65001.1 - 1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KIK65001.1 - 2.1e-05 24.2 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KIK65001.1 - 0.0072 15.3 0.3 0.016 14.2 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIK65001.1 - 0.03 13.9 1.6 0.042 13.4 0.2 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KIK65001.1 - 1.3 8.9 6.4 0.13 12.2 0.4 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KIK65001.1 - 6.5 6.2 5.5 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Cullin PF00888.22 KIK65002.1 - 9.3e-222 738.0 17.2 1.5e-113 380.6 3.6 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 KIK65002.1 - 3.1e-24 84.8 2.0 9.2e-24 83.3 2.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.20 KIK65002.1 - 0.048 14.0 0.2 0.15 12.4 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulator Fibritin_C PF07921.12 KIK65002.1 - 0.091 12.9 0.1 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Fibritin C-terminal region DUF3730 PF12530.8 KIK65002.1 - 0.11 12.1 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) RFC1 PF08519.12 KIK65002.1 - 1.3 9.2 7.4 3.6 7.7 0.2 3.5 2 1 0 3 3 3 0 Replication factor RFC1 C terminal domain Pre-PUA PF17832.1 KIK65003.1 - 1.7e-06 28.6 0.0 4.4e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Pre-PUA-like domain Peptidase_S32 PF05579.13 KIK65003.1 - 0.042 13.0 0.2 0.089 12.0 0.1 1.5 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.6 KIK65003.1 - 0.16 12.8 0.1 5.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Trypsin-like peptidase domain Trypsin_2 PF13365.6 KIK65005.1 - 0.1 13.5 0.1 6.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Trypsin-like peptidase domain Histone PF00125.24 KIK65006.1 - 3.1e-18 66.4 0.0 3.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK65006.1 - 2.2e-10 40.1 0.0 4.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK65006.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GST_N_3 PF13417.6 KIK65007.1 - 2.6e-20 72.6 0.1 5.6e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK65007.1 - 1.1e-18 67.3 0.1 2.8e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK65007.1 - 2.8e-12 46.8 0.3 5.1e-12 46.0 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK65007.1 - 6.9e-05 22.8 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK65007.1 - 0.00061 20.5 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KIK65007.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 KIK65007.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidohydro_2 PF04909.14 KIK65008.1 - 4.5e-30 105.4 0.0 5.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.14 KIK65009.1 - 3.1e-30 106.0 0.0 3.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.14 KIK65010.1 - 3.2e-31 109.2 0.0 4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase CsbD PF05532.12 KIK65011.1 - 0.00081 19.2 6.5 0.0014 18.5 6.5 1.5 1 0 0 1 1 1 1 CsbD-like F-box-like PF12937.7 KIK65013.1 - 0.0029 17.5 8.5 0.033 14.1 4.2 3.2 2 1 0 2 2 2 2 F-box-like LRR_4 PF12799.7 KIK65013.1 - 0.05 14.0 0.7 11 6.6 0.0 4.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK65013.1 - 0.11 12.4 8.2 1.5 8.8 6.2 3.4 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK65014.1 - 0.015 15.2 0.6 0.053 13.4 0.2 2.3 2 0 0 2 2 2 0 F-box-like BP28CT PF08146.12 KIK65016.1 - 2.2e-24 86.1 0.0 6e-24 84.7 0.0 1.9 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KIK65016.1 - 0.00013 22.3 0.1 0.00013 22.3 0.1 4.2 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KIK65016.1 - 0.014 15.6 11.8 0.99 9.8 0.2 6.1 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 KIK65016.1 - 3.1 8.4 8.0 57 4.4 0.1 5.9 6 0 0 6 6 6 0 HEAT-like repeat Polyketide_cyc2 PF10604.9 KIK65017.1 - 7e-11 42.6 0.0 1.4e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIK65017.1 - 9.6e-08 32.3 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIK65017.1 - 0.16 12.2 0.1 0.36 11.1 0.1 1.8 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KIK65018.1 - 4.5e-10 40.0 0.7 9.5e-10 38.9 0.7 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIK65018.1 - 7e-07 29.5 0.2 9.1e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pkinase_Tyr PF07714.17 KIK65019.1 - 1.2e-40 139.5 0.0 1.7e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65019.1 - 3.1e-30 105.4 0.0 5.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK65019.1 - 0.018 14.9 1.1 0.026 14.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK65019.1 - 0.24 11.0 0.0 0.54 9.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Nnf1 PF03980.14 KIK65020.1 - 0.016 15.6 0.3 0.022 15.1 0.3 1.2 1 0 0 1 1 1 0 Nnf1 DUF488 PF04343.13 KIK65020.1 - 0.026 15.1 0.3 0.045 14.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF488 DAP3 PF10236.9 KIK65020.1 - 0.027 13.7 0.3 0.16 11.1 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 KIK65020.1 - 0.03 14.2 0.4 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Omp_AT PF11557.8 KIK65020.1 - 0.038 13.0 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain RNA_helicase PF00910.22 KIK65020.1 - 0.098 13.0 1.6 0.68 10.3 0.2 2.4 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KIK65020.1 - 0.12 12.8 0.0 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIK65020.1 - 0.94 9.2 3.9 1 9.0 0.2 2.1 1 1 1 2 2 2 0 AAA domain Goodbye PF17109.5 KIK65021.1 - 3.3e-10 40.5 0.0 4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Pkinase_fungal PF17667.1 KIK65022.1 - 1.2e-59 202.1 0.0 1.9e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK65022.1 - 7.3e-07 28.8 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65022.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase NPR3 PF03666.13 KIK65023.1 - 4.2e-90 302.8 0.0 4.2e-90 302.8 0.0 3.6 2 2 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KIK65023.1 - 0.18 10.6 0.0 0.33 9.6 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Phage_Gp23 PF10669.9 KIK65023.1 - 1 9.7 4.7 2.4 8.5 4.7 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF3915 PF13054.6 KIK65023.1 - 7.7 6.5 11.9 11 6.0 9.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF1682 PF07946.14 KIK65023.1 - 9 5.4 12.8 16 4.6 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) p450 PF00067.22 KIK65024.1 - 1.8e-51 175.3 0.0 2.5e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 STAC2_u1 PF16664.5 KIK65026.1 - 0.015 15.7 2.7 0.015 15.7 2.7 1.8 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF1373 PF07117.11 KIK65026.1 - 0.021 14.8 0.2 0.021 14.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) MFS_1 PF07690.16 KIK65027.1 - 3.8e-29 101.7 25.2 3.8e-29 101.7 25.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KIK65027.1 - 0.91 9.9 4.0 2.6 8.5 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 DIOX_N PF14226.6 KIK65028.1 - 2.1e-16 60.7 0.2 1.1e-15 58.4 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK65028.1 - 6.5e-08 33.0 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIN_11 PF18479.1 KIK65028.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 PIN like domain LamB_YcsF PF03746.16 KIK65031.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 LamB/YcsF family SOG2 PF10428.9 KIK65032.1 - 0.91 8.6 14.4 0.94 8.6 14.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 KIK65032.1 - 5.3 5.8 13.1 6.3 5.5 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 KIK65032.1 - 7.4 6.5 18.7 8.5 6.3 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF979 PF06166.12 KIK65035.1 - 0.0066 15.7 0.4 0.0066 15.7 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF979) Cytochrom_B_C PF00032.17 KIK65035.1 - 0.46 10.8 6.3 1.4 9.3 0.3 2.5 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DDE_1 PF03184.19 KIK65037.1 - 5.3e-14 52.3 0.1 9.4e-14 51.4 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_I_A49 PF06870.12 KIK65044.1 - 5.9e-105 351.3 0.0 6.8e-105 351.1 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.28 KIK65045.1 - 3.5e-18 66.5 11.7 4.3e-18 66.3 0.3 4.1 2 2 0 2 2 2 1 SET domain SRI PF08236.11 KIK65045.1 - 2.6e-17 62.8 10.0 2.6e-17 62.8 10.0 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 KIK65045.1 - 8.3e-16 57.7 6.7 2.2e-15 56.4 6.7 1.8 1 0 0 1 1 1 1 AWS domain Pfg27 PF09216.10 KIK65045.1 - 0.013 15.4 0.3 0.032 14.1 0.3 1.6 1 0 0 1 1 1 0 Pfg27 Med26 PF08711.11 KIK65045.1 - 0.56 10.3 3.1 2.9 8.0 0.1 3.2 3 0 0 3 3 3 0 TFIIS helical bundle-like domain SRI PF08236.11 KIK65046.1 - 8.9e-17 61.1 9.6 1.1e-16 60.7 8.8 1.6 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SIR4_SID PF16991.5 KIK65046.1 - 0.029 14.4 2.0 0.087 12.9 2.0 1.8 1 0 0 1 1 1 0 Sir4 SID domain F-box-like PF12937.7 KIK65048.1 - 0.00031 20.6 1.0 0.0024 17.7 0.2 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK65048.1 - 0.079 12.9 1.5 1.1 9.2 0.6 3.2 2 1 0 2 2 2 0 F-box domain Glyco_hydro_106 PF17132.4 KIK65051.1 - 5.7e-25 87.7 0.0 2e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 KIK65051.1 - 0.002 18.0 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain HHH PF00633.23 KIK65051.1 - 0.16 11.9 0.4 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif Fungal_trans PF04082.18 KIK65054.1 - 1.6e-26 93.0 0.2 6.6e-26 90.9 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KIK65055.1 - 4.2e-26 91.7 64.2 2.4e-14 53.0 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK65056.1 - 2.7e-24 85.8 63.5 1.6e-14 53.6 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4B PF01349.17 KIK65058.1 - 0.06 12.7 0.9 0.11 11.9 0.9 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Tmemb_40 PF10160.9 KIK65058.1 - 0.19 11.2 11.8 0.24 10.8 1.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein DUF4199 PF13858.6 KIK65058.1 - 0.8 10.1 11.1 0.58 10.5 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) OST3_OST6 PF04756.13 KIK65058.1 - 0.89 8.8 13.7 0.032 13.6 3.9 2.1 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF4131 PF13567.6 KIK65058.1 - 1.1 8.9 10.9 1.4 8.5 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Complex1_LYR PF05347.15 KIK65059.1 - 4.2e-08 33.1 2.9 7.1e-08 32.4 2.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIK65059.1 - 2e-06 28.4 0.3 2.4e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.9 KIK65060.1 - 7.1e-27 93.7 15.5 7.1e-27 93.7 15.5 2.4 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 DNA_pol_phi PF04931.13 KIK65060.1 - 0.04 12.0 29.5 0.055 11.6 29.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KIK65060.1 - 0.077 12.1 28.2 0.091 11.9 28.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4763 PF15960.5 KIK65060.1 - 0.64 9.3 14.7 0.85 8.9 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) BSP_II PF05432.11 KIK65060.1 - 4.8 6.8 30.2 6.2 6.4 30.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 KIK65060.1 - 6.2 7.3 26.9 2.7 8.4 22.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Paramyxo_C PF01692.18 KIK65061.1 - 0.052 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C SWIB PF02201.18 KIK65065.1 - 1.1e-21 76.4 0.0 2.4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Sugar_tr PF00083.24 KIK65067.1 - 1.1e-98 331.0 19.3 1.3e-98 330.8 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK65067.1 - 3.5e-30 105.1 60.4 1.3e-25 90.1 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KIK65068.1 - 1.4e-33 114.5 0.0 5.2e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK65068.1 - 6.9e-05 22.8 0.0 0.15 12.1 0.0 2.6 3 0 0 3 3 3 2 RNA binding motif Calcipressin PF04847.12 KIK65068.1 - 0.00026 20.8 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 Calcipressin RRM_7 PF16367.5 KIK65068.1 - 0.01 15.9 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK65068.1 - 0.011 15.7 0.0 2.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KIK65068.1 - 0.012 15.5 0.0 0.43 10.5 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif Sugar_tr PF00083.24 KIK65072.1 - 1.8e-34 119.4 15.6 2.4e-34 119.0 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK65072.1 - 2.1e-34 119.0 26.4 2.6e-34 118.7 25.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase_fungal PF17667.1 KIK65073.1 - 2.4e-60 204.5 0.0 2.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK65073.1 - 1e-06 28.3 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65073.1 - 0.12 11.6 0.0 0.36 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein tyrosine kinase Rtt106 PF08512.12 KIK65074.1 - 1.1e-15 57.8 0.0 2.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KIK65074.1 - 0.017 15.1 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 KIK65077.1 - 3.5e-16 59.1 45.7 1.2e-14 54.0 32.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIK65077.1 - 5.1 5.8 22.5 0.8 8.5 9.1 2.3 1 1 1 2 2 2 0 MFS_1 like family Cys_Met_Meta_PP PF01053.20 KIK65078.1 - 6.1e-144 479.3 0.0 6.9e-144 479.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK65078.1 - 3.1e-12 46.4 0.1 4.7e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIK65078.1 - 7.1e-12 45.3 0.6 1.2e-11 44.5 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIK65078.1 - 5e-11 42.2 0.1 9.3e-11 41.3 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK65078.1 - 5.4e-06 25.9 0.0 9.8e-06 25.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KIK65078.1 - 0.00014 20.5 0.2 0.00021 19.9 0.2 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KIK65078.1 - 0.0013 17.7 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SepSecS PF05889.13 KIK65078.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF99 PF01949.16 KIK65078.1 - 0.13 11.6 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 MFS_1 PF07690.16 KIK65080.1 - 3.8e-39 134.6 50.9 5.9e-39 134.0 49.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK65080.1 - 2.7e-14 52.9 8.8 2.7e-14 52.9 8.8 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Zw10 PF06248.13 KIK65080.1 - 0.037 12.6 0.1 0.093 11.3 0.0 1.6 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Cys_Met_Meta_PP PF01053.20 KIK65081.1 - 4.5e-128 427.0 0.0 8.8e-128 426.1 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK65081.1 - 3.6e-06 26.4 0.0 6.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIK65081.1 - 3.9e-06 26.4 0.1 7.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIK65081.1 - 4.4e-06 25.9 0.7 6.9e-06 25.3 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KIK65081.1 - 0.0029 16.2 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KIK65081.1 - 0.0068 15.7 0.0 0.026 13.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KIK65081.1 - 0.022 13.6 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Med21 PF11221.8 KIK65084.1 - 2.6e-20 73.1 1.8 3.5e-20 72.7 1.8 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Guanylate_cyc PF00211.20 KIK65087.1 - 4.5e-19 68.8 0.0 7.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GIT_SHD PF08518.11 KIK65087.1 - 7.8e-19 67.0 2.5 2.8e-08 33.3 0.4 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Pkinase_Tyr PF07714.17 KIK65088.1 - 2.2e-28 99.3 0.0 2.4e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65088.1 - 6.5e-25 88.0 0.0 7.6e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK65088.1 - 0.0019 17.0 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK65088.1 - 0.019 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KIK65088.1 - 0.035 13.4 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KIK65089.1 - 7.6e-60 202.5 0.0 1.1e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65089.1 - 1.8e-32 112.6 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65089.1 - 6.9e-08 32.1 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK65089.1 - 0.00046 19.2 0.2 0.00076 18.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIK65089.1 - 0.0046 16.6 0.7 0.0078 15.8 0.7 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KIK65090.1 - 9.3e-08 31.7 0.0 1.1e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65090.1 - 0.0003 20.3 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65091.1 - 1.1e-28 100.2 0.0 1.3e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65091.1 - 2.3e-24 86.2 0.0 2.7e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK65091.1 - 0.00098 18.0 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK65091.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KIK65091.1 - 0.038 13.3 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KIK65091.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peroxidase_2 PF01328.17 KIK65092.1 - 1.7e-23 84.1 0.1 1.8e-23 84.1 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Alpha-L-AF_C PF06964.12 KIK65094.1 - 1.8e-23 83.5 0.7 2.5e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KIK65094.1 - 0.00038 20.7 1.2 0.0017 18.7 0.4 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain Lyase_1 PF00206.20 KIK65095.1 - 1.3e-21 77.3 0.0 1.9e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KIK65095.1 - 1.5e-18 67.1 0.0 4.9e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Tyrosinase PF00264.20 KIK65099.1 - 1.2e-45 156.5 0.4 1.7e-45 156.0 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIK65099.1 - 1.3e-08 35.5 0.0 2.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain G_glu_transpept PF01019.21 KIK65100.1 - 2.5e-144 481.9 0.0 2.8e-144 481.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DAO PF01266.24 KIK65100.1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase COesterase PF00135.28 KIK65101.1 - 2.7e-55 188.2 0.0 4.4e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK65101.1 - 4e-06 26.8 0.0 9.4e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.21 KIK65102.1 - 1.9e-13 50.4 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KIK65102.1 - 0.00016 21.4 0.4 0.0004 20.1 0.1 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KIK65102.1 - 0.1 10.9 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) AA_permease_2 PF13520.6 KIK65103.1 - 6.9e-55 186.6 58.0 8.4e-55 186.3 58.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK65103.1 - 2.2e-13 49.6 51.1 3.8e-13 48.8 51.1 1.4 1 1 0 1 1 1 1 Amino acid permease MatE PF01554.18 KIK65104.1 - 1.8e-48 164.2 30.3 2.4e-26 92.3 10.8 3.0 3 0 0 3 3 3 2 MatE DUF1980 PF09323.10 KIK65104.1 - 0.27 11.1 1.5 0.63 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3112 PF11309.8 KIK65104.1 - 4.8 6.6 5.6 17 4.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) MatE PF01554.18 KIK65106.1 - 2e-53 180.4 30.9 7e-28 97.3 6.0 2.9 3 0 0 3 3 3 2 MatE DUF1980 PF09323.10 KIK65106.1 - 0.19 11.6 3.5 0.3 11.0 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) DUF3112 PF11309.8 KIK65106.1 - 2.2 7.7 4.5 18 4.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Arginase PF00491.21 KIK65107.1 - 2.4e-89 299.6 0.0 3.1e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIK65107.1 - 0.053 13.7 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Arginase PF00491.21 KIK65108.1 - 1.6e-85 287.0 0.0 2.2e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIK65108.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Baculo_PEP_C PF04513.12 KIK65109.1 - 0.011 15.7 8.0 0.031 14.3 8.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 KIK65109.1 - 0.022 14.7 0.0 0.46 10.4 0.0 2.0 1 1 1 2 2 2 0 Sec34-like family RPW8 PF05659.11 KIK65109.1 - 0.037 13.7 0.1 0.56 9.9 0.0 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LURAP PF14854.6 KIK65109.1 - 0.16 11.9 0.1 1 9.3 0.0 1.9 2 0 0 2 2 2 0 Leucine rich adaptor protein DUF5635 PF18685.1 KIK65109.1 - 1.1 9.3 3.9 2.5 8.1 0.5 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5635) zf-C2H2 PF00096.26 KIK65112.1 - 0.00029 21.1 4.5 0.012 16.1 0.0 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK65112.1 - 0.066 14.1 11.3 0.11 13.5 0.3 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger MIF4G PF02854.19 KIK65112.1 - 0.21 11.2 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain FOXP-CC PF16159.5 KIK65112.1 - 0.52 11.0 5.7 6.9 7.4 0.9 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIK65112.1 - 1.9 9.1 5.5 1.9 9.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain OTU PF02338.19 KIK65113.1 - 1.6e-11 44.8 0.0 2.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.13 KIK65113.1 - 1.3e-05 25.4 10.3 1.3e-05 25.4 10.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 KIK65113.1 - 1.3 7.0 13.9 2.6 6.0 13.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF4770 PF15994.5 KIK65113.1 - 1.5 9.1 4.0 5.3 7.2 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) ADH_zinc_N PF00107.26 KIK65114.1 - 1e-16 61.1 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK65114.1 - 6.2e-06 26.1 0.2 0.00015 21.6 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK65114.1 - 8.1e-05 23.7 0.0 0.00018 22.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KIK65114.1 - 0.063 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F-box-like PF12937.7 KIK65115.1 - 2.3e-07 30.6 0.3 5.5e-07 29.4 0.3 1.6 1 1 0 1 1 1 1 F-box-like Bcr-Abl_Oligo PF09036.10 KIK65115.1 - 0.017 15.1 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain FliJ PF02050.16 KIK65115.1 - 0.035 14.3 0.4 0.046 13.9 0.4 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein ANAPC5 PF12862.7 KIK65115.1 - 0.039 14.0 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Spc24 PF08286.11 KIK65115.1 - 0.089 13.0 1.1 0.16 12.2 0.7 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF5638 PF18688.1 KIK65115.1 - 0.14 12.5 0.3 0.18 12.1 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5638) RIO1 PF01163.22 KIK65118.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIK65118.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIK65118.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65118.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase SF3b10 PF07189.11 KIK65120.1 - 2.9e-35 120.2 0.1 3.5e-35 120.0 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ion_trans PF00520.31 KIK65121.1 - 1.2e-104 348.9 80.7 5.4e-37 127.3 13.2 6.8 5 2 1 6 6 6 6 Ion transport protein PKD_channel PF08016.12 KIK65121.1 - 2.7e-05 23.1 61.5 0.00036 19.3 9.1 7.0 5 2 2 7 7 7 5 Polycystin cation channel UPF0193 PF05250.11 KIK65121.1 - 0.27 11.0 0.0 0.47 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) CAAD PF14159.6 KIK65122.1 - 0.16 11.9 3.8 0.51 10.2 0.4 2.9 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Myelin_PLP PF01275.19 KIK65122.1 - 7 6.4 10.0 0.86 9.4 1.6 2.4 1 1 1 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) EHN PF06441.12 KIK65124.1 - 2.2e-35 121.3 0.2 2e-34 118.2 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK65124.1 - 2.3e-09 37.3 0.2 3.4e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK65124.1 - 0.00061 20.5 2.0 0.00061 20.5 2.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Pkinase_fungal PF17667.1 KIK65125.1 - 6.9e-23 81.1 0.0 8.7e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK65125.1 - 7e-06 25.6 0.0 9.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK65125.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK65127.1 - 4.9e-19 68.4 0.0 1.1e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK65127.1 - 9.6e-06 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SBP_bac_10 PF07596.11 KIK65127.1 - 0.032 14.2 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Pkinase_Tyr PF07714.17 KIK65127.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK65128.1 - 1.1e-08 34.2 0.0 1.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK65128.1 - 0.057 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KIK65128.1 - 0.12 12.2 0.1 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK65129.1 - 2.4e-25 89.2 0.0 1.4e-20 73.5 0.0 2.2 1 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK65129.1 - 0.00026 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK65130.1 - 5.2e-25 88.1 0.0 1.5e-20 73.4 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK65130.1 - 0.0003 20.2 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PTN_MK_C PF01091.18 KIK65130.1 - 0.016 15.6 0.6 0.11 12.9 0.3 2.3 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Pkinase_fungal PF17667.1 KIK65131.1 - 5.3e-10 38.6 0.0 7.8e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK65134.1 - 2e-69 233.9 0.0 2.6e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65134.1 - 6.3e-30 104.3 0.0 9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK65134.1 - 4.8e-05 22.5 0.8 0.00049 19.2 0.8 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK65134.1 - 0.0013 18.7 0.3 0.0038 17.2 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK65134.1 - 0.0062 16.2 0.1 0.0097 15.5 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 KIK65134.1 - 0.04 13.0 0.0 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 FeoB_N PF02421.18 KIK65134.1 - 0.15 11.5 0.2 0.26 10.8 0.2 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KIK65135.1 - 3.2e-49 167.9 0.0 5.4e-49 167.2 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KIK65135.1 - 0.00082 19.0 0.0 0.0025 17.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KIK65135.1 - 0.037 13.5 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Myc_N PF01056.18 KIK65135.1 - 0.088 12.7 0.8 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SAD_SRA PF02182.17 KIK65136.1 - 3.8e-49 166.4 0.0 4.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 SAD/SRA domain Steroid_dh PF02544.16 KIK65137.1 - 1.6 8.7 8.7 16 5.5 0.1 3.8 2 1 3 5 5 5 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2569 PF10754.9 KIK65137.1 - 9.1 6.7 15.5 0.12 12.8 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) SEP PF08059.13 KIK65138.1 - 1.8e-26 92.5 0.0 6.8e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KIK65138.1 - 5.3e-16 58.6 0.1 7.8e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 UBX domain OB_aCoA_assoc PF01796.17 KIK65138.1 - 0.035 14.1 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated p450 PF00067.22 KIK65139.1 - 3.6e-53 181.0 0.0 6.4e-53 180.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Malate_DH PF12434.8 KIK65140.1 - 1.1 9.3 5.1 0.42 10.7 1.8 2.0 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Kdo PF06293.14 KIK65141.1 - 1.7e-10 40.7 0.0 4.2e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIK65141.1 - 3.9e-05 23.1 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KIK65141.1 - 0.00044 20.2 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK65141.1 - 0.00074 19.0 0.0 0.00079 18.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK65141.1 - 0.025 14.2 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KIK65141.1 - 0.036 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GvpO PF05800.11 KIK65141.1 - 0.037 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Pkinase_Tyr PF07714.17 KIK65141.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase SF3b10 PF07189.11 KIK65142.1 - 1.2e-35 121.4 0.1 1.5e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) F-box-like PF12937.7 KIK65143.1 - 1.3e-07 31.3 2.2 1.4e-06 28.1 0.1 2.7 2 0 0 2 2 2 1 F-box-like GAS PF13851.6 KIK65143.1 - 0.039 13.3 0.6 0.065 12.6 0.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KIK65143.1 - 0.044 13.6 0.8 0.091 12.5 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3847 PF12958.7 KIK65143.1 - 0.051 13.7 1.0 0.1 12.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) HR1 PF02185.16 KIK65143.1 - 0.08 13.1 0.6 0.18 12.0 0.6 1.5 1 0 0 1 1 1 0 Hr1 repeat PEARLI-4 PF05278.12 KIK65143.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) NPV_P10 PF05531.12 KIK65143.1 - 0.18 12.3 0.1 0.58 10.7 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 KIK65143.1 - 2.1 8.7 5.0 7.8 6.8 1.4 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain MAGE PF01454.19 KIK65144.1 - 1.8e-50 171.6 0.0 2.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family DUF1348 PF07080.11 KIK65144.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) ADH_zinc_N PF00107.26 KIK65147.1 - 9.1e-30 103.3 1.5 1.2e-29 102.9 0.7 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK65147.1 - 6.3e-17 62.9 0.0 1.3e-16 61.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK65147.1 - 1.3e-11 44.3 0.2 5.9e-10 39.0 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Patatin PF01734.22 KIK65149.1 - 4e-25 89.2 0.0 1.1e-24 87.8 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Patatin PF01734.22 KIK65150.1 - 1.9e-07 31.5 0.0 9.6e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Patatin PF01734.22 KIK65151.1 - 1.8e-08 34.8 0.0 3.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase F-box-like PF12937.7 KIK65153.1 - 1.7e-08 34.3 2.1 2.9e-08 33.4 0.7 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK65153.1 - 0.15 12.6 2.8 29 5.2 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Peroxidase_2 PF01328.17 KIK65154.1 - 2.3e-47 161.9 0.0 2.8e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PCI PF01399.27 KIK65155.1 - 2.5e-07 31.1 0.5 2.3e-06 28.1 0.0 2.8 2 1 0 2 2 2 1 PCI domain GPHR_N PF12537.8 KIK65156.1 - 0.027 14.6 0.3 10 6.3 0.0 2.7 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF3149 PF11346.8 KIK65156.1 - 0.84 9.3 0.1 0.84 9.3 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) DDE_Tnp_4 PF13359.6 KIK65157.1 - 4.6e-08 32.9 0.0 6.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Alginate_lyase PF05426.12 KIK65160.1 - 2.1e-11 43.9 0.1 7e-10 38.9 0.1 2.2 2 0 0 2 2 2 2 Alginate lyase Alginate_lyase PF05426.12 KIK65161.1 - 3.3e-14 53.1 2.7 3.3e-13 49.8 2.7 2.0 1 1 0 1 1 1 1 Alginate lyase Macoilin PF09726.9 KIK65162.1 - 0.42 9.1 9.7 0.28 9.7 1.1 2.1 2 0 0 2 2 2 0 Macoilin family TPR_10 PF13374.6 KIK65163.1 - 4.3e-114 369.8 2.3 1.7e-09 37.2 0.0 13.1 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK65163.1 - 1.5e-104 342.4 42.6 1.6e-13 50.7 0.3 12.1 1 1 12 13 13 13 13 Tetratricopeptide repeat TPR_8 PF13181.6 KIK65163.1 - 6.8e-26 88.3 22.5 0.076 13.3 0.0 12.2 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_1 PF00515.28 KIK65163.1 - 1.6e-23 81.5 35.6 0.022 14.6 0.0 12.2 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65163.1 - 3.2e-21 73.7 24.5 0.23 11.7 0.0 12.3 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65163.1 - 1.4e-19 68.6 18.8 0.17 12.0 0.0 11.5 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_4 PF07721.14 KIK65163.1 - 4.6e-11 42.2 0.0 15 6.6 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.20 KIK65163.1 - 8.8e-09 35.0 3.6 24 5.4 0.0 9.0 9 0 0 9 9 9 0 PPR repeat TPR_14 PF13428.6 KIK65163.1 - 2.7e-08 34.0 2.3 19 6.4 0.0 8.8 8 1 2 10 10 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK65163.1 - 3.5e-08 33.3 30.1 1.7 9.2 0.0 10.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK65163.1 - 1.3e-07 31.8 13.4 11 6.9 0.0 10.4 11 0 0 11 11 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK65163.1 - 2.3e-07 30.9 4.9 18 5.6 0.1 7.6 3 3 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK65163.1 - 4.5e-07 30.3 8.6 0.55 10.8 0.3 7.7 4 4 7 11 11 11 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK65163.1 - 8.4e-07 28.7 0.4 0.26 10.6 0.0 4.1 2 2 1 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 KIK65163.1 - 1.9e-06 28.4 0.8 10 6.8 0.0 8.5 11 1 0 11 11 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK65163.1 - 0.00015 21.8 5.2 7 6.8 0.0 6.5 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KIK65163.1 - 0.0009 19.3 0.0 3.2 7.8 0.0 4.7 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 KIK65163.1 - 0.0017 18.0 13.8 43 3.9 0.0 8.7 9 0 0 9 9 9 0 TPR repeat Paf67 PF10255.9 KIK65163.1 - 0.006 15.6 0.0 1 8.3 0.0 3.2 3 1 0 3 3 3 1 RNA polymerase I-associated factor PAF67 MCPVI PF02993.14 KIK65163.1 - 0.038 13.8 0.4 76 3.0 0.0 4.7 4 2 1 5 5 5 0 Minor capsid protein VI YjgF_endoribonc PF14588.6 KIK65163.1 - 0.12 12.5 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease DUF2205 PF10224.9 KIK65163.1 - 0.15 12.1 4.1 38 4.4 0.0 4.8 5 0 0 5 5 5 0 Short coiled-coil protein MIT PF04212.18 KIK65163.1 - 0.21 11.7 0.7 30 4.8 0.0 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Vps39_1 PF10366.9 KIK65163.1 - 0.4 11.0 18.7 25 5.2 0.3 7.8 2 2 5 9 9 9 0 Vacuolar sorting protein 39 domain 1 MUG113 PF13455.6 KIK65166.1 - 3e-09 37.4 0.0 6.9e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK65166.1 - 1.1e-07 32.4 0.0 2.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain KDZ PF18758.1 KIK65167.1 - 0.00058 19.5 0.7 0.00062 19.4 0.7 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase F-box PF00646.33 KIK65172.1 - 0.036 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF4208 PF13907.6 KIK65173.1 - 0.03 14.7 0.2 0.087 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) DUF4347 PF14252.6 KIK65173.1 - 0.07 13.0 0.2 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Pkip-1 PF06878.11 KIK65173.1 - 0.17 12.0 1.5 0.3 11.2 1.5 1.4 1 0 0 1 1 1 0 Pkip-1 protein T6PP_N PF18572.1 KIK65173.1 - 0.87 9.5 7.9 6.4 6.7 2.7 2.4 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain ALMT PF11744.8 KIK65173.1 - 5.8 5.6 5.5 8.6 5.1 5.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Rx_N PF18052.1 KIK65174.1 - 0.012 15.9 0.7 0.02 15.2 0.7 1.4 1 0 0 1 1 1 0 Rx N-terminal domain SSXRD PF09514.10 KIK65174.1 - 0.022 14.3 0.3 0.044 13.4 0.3 1.5 1 0 0 1 1 1 0 SSXRD motif DUF3683 PF12447.8 KIK65174.1 - 0.14 12.3 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) PIN_4 PF13638.6 KIK65179.1 - 2.6e-08 34.2 0.1 5e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 PIN domain DUF2325 PF10087.9 KIK65179.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Ctr PF04145.15 KIK65180.1 - 1.6e-24 87.2 0.2 2e-24 86.9 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4870 PF09685.10 KIK65180.1 - 0.14 12.3 0.3 0.14 12.3 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) GRDP-like PF07173.12 KIK65181.1 - 7.7e-09 36.3 10.7 4e-07 30.8 2.2 4.2 4 1 0 4 4 4 2 Glycine-rich domain-containing protein-like DUF3646 PF12362.8 KIK65181.1 - 0.013 15.8 0.1 0.03 14.6 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal CBM_1 PF00734.18 KIK65182.1 - 1.7e-13 50.2 11.7 5.8e-13 48.6 11.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain EHN PF06441.12 KIK65183.1 - 1.4e-34 118.7 0.1 2.6e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK65183.1 - 4.3e-13 49.5 0.2 7e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK65183.1 - 0.00025 21.7 4.8 0.00059 20.5 4.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Prefoldin PF02996.17 KIK65184.1 - 9e-27 93.4 0.4 1.1e-26 93.1 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KIK65184.1 - 4.2e-05 23.5 5.2 0.00045 20.1 0.5 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF2552 PF10827.8 KIK65184.1 - 0.0033 17.6 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2552) Med30 PF11315.8 KIK65184.1 - 0.018 15.3 1.4 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 Prefoldin_3 PF13758.6 KIK65184.1 - 0.019 15.0 0.1 0.047 13.8 0.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit AIP3 PF03915.13 KIK65184.1 - 0.019 14.1 2.0 0.02 14.0 2.0 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4140 PF13600.6 KIK65184.1 - 0.069 13.6 0.4 12 6.5 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) T3SSipB PF16535.5 KIK65184.1 - 0.071 13.6 3.9 0.36 11.3 0.2 2.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB COG2 PF06148.11 KIK65184.1 - 0.1 12.7 3.5 2 8.5 1.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TSNAXIP1_N PF15739.5 KIK65184.1 - 0.12 12.7 4.2 1.9 8.9 0.1 2.1 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF1664 PF07889.12 KIK65184.1 - 0.13 12.3 5.7 3.4 7.7 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KIK65184.1 - 0.2 11.8 4.6 3.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ABC2_membrane_3 PF12698.7 KIK65184.1 - 0.25 10.4 2.7 0.29 10.2 2.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Uteroglobin PF01099.17 KIK65184.1 - 0.29 11.5 2.7 0.51 10.7 0.2 2.1 2 0 0 2 2 2 0 Uteroglobin family XhlA PF10779.9 KIK65184.1 - 0.32 11.2 4.5 4.6 7.5 0.9 2.3 2 0 0 2 2 2 0 Haemolysin XhlA RasGAP_C PF03836.15 KIK65184.1 - 0.35 11.0 5.2 4.8 7.3 0.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus HlyE PF06109.13 KIK65184.1 - 0.37 10.1 5.1 0.93 8.7 5.1 1.7 1 1 0 1 1 1 0 Haemolysin E (HlyE) Laminin_II PF06009.12 KIK65184.1 - 0.58 10.2 6.8 4 7.5 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II zf-C4H2 PF10146.9 KIK65184.1 - 0.91 9.8 4.9 3 8.1 0.8 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein Stathmin PF00836.19 KIK65184.1 - 2.2 8.3 7.1 2 8.4 2.1 2.1 2 0 0 2 2 2 0 Stathmin family DUF2347 PF09804.9 KIK65185.1 - 1.7e-47 162.3 0.0 2.3e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KIK65185.1 - 9.4e-08 31.1 0.0 0.018 13.8 0.1 3.1 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.10 KIK65185.1 - 0.00039 20.3 0.0 0.00086 19.2 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis MFS_1 PF07690.16 KIK65186.1 - 1e-16 60.8 51.0 1.1e-10 41.0 31.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily AMP-binding PF00501.28 KIK65187.1 - 7.1e-23 80.9 0.0 2.5e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK65187.1 - 5.4e-20 71.7 0.0 9.4e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIK65187.1 - 6.2e-10 38.9 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK65187.1 - 0.13 11.3 0.0 0.83 8.6 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.28 KIK65188.1 - 1.3e-25 89.9 0.0 2.6e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK65188.1 - 1.1e-07 32.2 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIK65188.1 - 0.033 14.5 0.1 0.14 12.6 0.1 2.1 1 1 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KIK65189.1 - 1.1e-06 29.3 0.0 4.5e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK65189.1 - 4.1e-05 24.1 0.0 0.00021 21.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK65189.1 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK65189.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SHOCT PF09851.9 KIK65189.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain Ski_Sno PF02437.17 KIK65189.1 - 0.052 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 SKI/SNO/DAC family Ubie_methyltran PF01209.18 KIK65189.1 - 0.07 12.5 0.0 0.26 10.6 0.0 1.8 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family YcaO PF02624.16 KIK65189.1 - 0.19 11.0 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Methyltransf_2 PF00891.18 KIK65190.1 - 1.1e-20 73.8 0.1 4.7e-19 68.5 0.1 2.3 1 1 0 1 1 1 1 O-methyltransferase domain DprA_WH PF17782.1 KIK65190.1 - 0.0069 16.5 0.1 0.05 13.7 0.0 2.4 2 0 0 2 2 2 1 DprA winged helix domain MarR_2 PF12802.7 KIK65190.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 KIK65190.1 - 0.038 13.8 0.3 0.33 10.8 0.0 2.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain TrmB PF01978.19 KIK65190.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Dimerisation2 PF16864.5 KIK65190.1 - 0.092 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain RPA_C PF08784.11 KIK65190.1 - 0.1 13.3 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Replication protein A C terminal Sulfotransfer_1 PF00685.27 KIK65191.1 - 0.034 13.6 0.3 0.042 13.3 0.3 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KIK65192.1 - 9.3e-05 22.9 0.0 0.00011 22.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF639 PF04842.12 KIK65192.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) p450 PF00067.22 KIK65194.1 - 1.2e-32 113.3 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIK65195.1 - 9.5e-39 133.3 55.4 9.5e-39 133.3 55.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK65195.1 - 1.5e-19 69.9 23.4 3.6e-19 68.6 23.4 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK65195.1 - 6.2e-12 45.1 13.0 6.2e-12 45.1 13.0 2.9 4 0 0 4 4 4 2 Sugar (and other) transporter Pax7 PF12360.8 KIK65195.1 - 0.025 14.7 0.2 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Paired box protein 7 GMC_oxred_N PF00732.19 KIK65197.1 - 4.6e-53 180.5 0.0 6.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK65197.1 - 7e-24 85.0 0.0 1.3e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK65197.1 - 0.0067 16.6 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK65197.1 - 0.0088 15.7 0.8 0.048 13.2 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK65197.1 - 0.013 14.8 0.1 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KIK65197.1 - 0.034 13.2 0.2 0.06 12.4 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ArsA_ATPase PF02374.15 KIK65197.1 - 0.054 12.7 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase FAD_binding_2 PF00890.24 KIK65197.1 - 0.12 11.5 0.4 0.21 10.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain rhaM PF05336.13 KIK65197.1 - 0.15 12.1 0.6 0.26 11.3 0.6 1.3 1 0 0 1 1 1 0 L-rhamnose mutarotase Pyr_redox_3 PF13738.6 KIK65197.1 - 0.22 10.7 0.4 3.3 6.9 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Retrotran_gag_2 PF14223.6 KIK65198.1 - 2.5e-11 43.4 0.2 3.9e-11 42.8 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KIK65200.1 - 2.9e-14 52.9 0.1 4.1e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FRB_dom PF08771.11 KIK65200.1 - 0.051 14.0 0.9 0.69 10.4 0.1 2.1 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain GMC_oxred_N PF00732.19 KIK65201.1 - 3.3e-66 223.7 0.0 4.3e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK65201.1 - 2.3e-36 125.4 0.0 3.8e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK65201.1 - 0.021 15.0 0.3 0.056 13.7 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK65201.1 - 0.03 13.5 0.1 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK65201.1 - 0.13 11.3 0.5 2.3 7.2 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIK65201.1 - 0.19 10.8 0.5 0.34 9.9 0.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 8TM_micro PF17028.5 KIK65203.1 - 0.081 12.6 0.0 0.086 12.5 0.0 1.0 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain TPR_12 PF13424.6 KIK65205.1 - 9.8e-46 153.9 5.2 9.1e-13 48.3 0.1 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIK65205.1 - 1e-42 142.8 5.0 1.7e-10 40.4 0.0 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK65205.1 - 5.9e-12 44.8 2.4 0.2 12.0 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK65205.1 - 6.1e-11 41.7 4.2 0.14 12.0 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65205.1 - 8.5e-11 41.1 2.4 0.045 13.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65205.1 - 2.4e-10 39.7 4.7 0.77 10.0 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIK65205.1 - 2.9e-06 27.3 0.3 7.9 7.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK65205.1 - 0.00012 22.5 2.3 15 6.5 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK65205.1 - 0.00036 20.9 0.1 14 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK65205.1 - 0.0051 17.4 0.1 4 8.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK65205.1 - 0.012 15.8 0.5 1 9.7 0.1 3.4 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIK65205.1 - 0.03 14.8 0.5 6.1 7.4 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Focal_AT PF03623.13 KIK65205.1 - 0.031 14.3 0.1 2.9 7.9 0.0 2.7 2 1 1 3 3 3 0 Focal adhesion targeting region PPR PF01535.20 KIK65205.1 - 0.047 13.9 0.9 97 3.6 0.0 4.6 5 0 0 5 5 5 0 PPR repeat TPR_11 PF13414.6 KIK65205.1 - 0.066 12.9 1.7 9.3 6.0 0.0 3.9 5 0 0 5 5 5 0 TPR repeat ChW PF07538.11 KIK65205.1 - 0.093 12.7 0.5 5.5 7.0 0.1 2.8 2 1 0 2 2 2 0 Clostridial hydrophobic W BTAD PF03704.17 KIK65205.1 - 0.12 12.8 0.2 10 6.6 0.0 3.1 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 KIK65205.1 - 0.15 12.2 2.5 14 5.9 0.1 4.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KIK65206.1 - 5.1e-37 126.0 13.6 6.1e-14 52.1 0.2 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIK65206.1 - 3.9e-34 115.6 1.1 1.9e-09 37.1 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65206.1 - 2.6e-08 33.4 6.4 0.00066 19.6 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK65206.1 - 5.6e-08 33.3 0.6 0.00063 20.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK65206.1 - 8.3e-08 31.7 4.5 0.0012 18.5 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK65206.1 - 3.3e-07 30.7 3.4 0.18 12.3 0.1 4.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK65206.1 - 3.4e-07 30.0 9.3 0.0011 19.0 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65206.1 - 1.4e-06 27.9 6.4 0.17 11.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK65206.1 - 0.00014 22.2 0.0 0.16 12.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK65206.1 - 0.0003 20.8 0.1 8.9 6.5 0.0 4.4 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KIK65206.1 - 0.00032 20.9 1.7 0.041 14.1 0.1 3.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIK65206.1 - 0.00082 20.0 1.1 0.68 10.9 0.1 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK65206.1 - 0.0014 18.8 0.6 0.087 13.0 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK65206.1 - 0.012 16.2 4.5 3.6 8.4 0.0 5.0 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK65206.1 - 0.021 15.2 1.9 2.7 8.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK65206.1 - 0.026 14.2 1.7 5.9 6.7 0.0 3.0 3 0 0 3 3 3 0 TPR repeat Foie-gras_1 PF11817.8 KIK65206.1 - 0.036 13.7 0.6 57 3.2 0.0 3.8 4 0 0 4 4 4 0 Foie gras liver health family 1 DUF3856 PF12968.7 KIK65206.1 - 0.083 13.0 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) MT0933_antitox PF14013.6 KIK65206.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 MT0933-like antitoxin protein TPR_3 PF07720.12 KIK65206.1 - 0.41 10.7 2.4 9 6.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ALIX_LYPXL_bnd PF13949.6 KIK65207.1 - 0.0036 16.6 4.9 0.0052 16.1 4.9 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3945 PF13101.6 KIK65207.1 - 0.0068 16.1 0.3 0.03 14.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3945) Fib_alpha PF08702.10 KIK65207.1 - 0.037 14.2 4.3 3.2 7.9 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YlqD PF11068.8 KIK65207.1 - 0.095 13.1 7.5 0.17 12.2 7.5 1.5 1 1 0 1 1 1 0 YlqD protein Med9 PF07544.13 KIK65207.1 - 0.33 11.1 5.7 10 6.3 2.4 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF730 PF05325.11 KIK65207.1 - 0.33 11.0 2.1 0.63 10.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) TMF_DNA_bd PF12329.8 KIK65207.1 - 0.43 10.6 10.4 1.8 8.6 1.7 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 KIK65207.1 - 0.62 10.5 10.1 0.82 10.1 0.9 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CC2-LZ PF16516.5 KIK65207.1 - 1 9.8 9.1 33 4.9 9.1 2.3 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator THOC7 PF05615.13 KIK65207.1 - 2.8 8.2 12.3 97 3.2 12.3 2.4 1 1 0 1 1 1 0 Tho complex subunit 7 Seryl_tRNA_N PF02403.22 KIK65207.1 - 3.5 7.9 9.5 14 6.0 0.2 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KIK65207.1 - 3.9 6.3 12.4 12 4.7 7.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein FHA PF00498.26 KIK65208.1 - 3.5e-09 36.9 0.0 7.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain APC_u14 PF16635.5 KIK65208.1 - 0.016 15.8 0.1 0.016 15.8 0.1 2.3 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Insulin_TMD PF17870.1 KIK65209.1 - 0.098 12.7 2.5 0.25 11.4 1.5 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Amnionless PF14828.6 KIK65209.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless SHR3_chaperone PF08229.11 KIK65209.1 - 0.21 10.6 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 SKG6 PF08693.10 KIK65209.1 - 1.7 8.1 6.1 4.6 6.7 6.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.11 KIK65209.1 - 1.9 8.6 3.6 1.4 9.0 0.5 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Glyco_hydro_16 PF00722.21 KIK65210.1 - 2.3e-17 63.0 0.8 4.5e-17 62.1 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 KIK65212.1 - 8e-60 202.1 0.5 8e-60 202.1 0.5 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK65212.1 - 1.3e-07 31.8 0.0 3.3e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK65212.1 - 0.0041 17.0 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK65212.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 Aldo_ket_red PF00248.21 KIK65214.1 - 6.9e-49 166.6 0.0 4.7e-48 163.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_10 PF13374.6 KIK65215.1 - 9.2e-64 209.8 2.2 3.3e-10 39.5 0.0 9.1 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK65215.1 - 1.3e-53 179.1 7.4 7.1e-11 42.2 0.1 7.1 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65215.1 - 2e-13 49.3 12.5 0.86 9.8 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65215.1 - 1e-12 47.1 15.1 0.012 15.7 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK65215.1 - 2.5e-12 46.0 18.2 0.095 12.6 0.0 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK65215.1 - 7.2e-12 44.5 16.0 0.063 13.5 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK65215.1 - 2e-10 41.0 9.6 0.013 16.0 0.1 6.9 2 2 6 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK65215.1 - 2.4e-10 40.5 2.6 0.0091 16.2 0.0 5.7 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KIK65215.1 - 4.3e-09 36.9 1.2 0.0074 16.9 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK65215.1 - 6.5e-09 35.6 0.2 0.99 10.2 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK65215.1 - 1.2e-05 25.4 2.7 4.8 7.4 0.0 5.1 3 2 3 7 7 7 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIK65215.1 - 3.2e-05 23.9 0.1 0.53 10.3 0.0 4.7 2 2 1 3 3 3 1 Putative TPR-like repeat TPR_17 PF13431.6 KIK65215.1 - 0.00014 22.0 15.9 0.081 13.3 0.1 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK65215.1 - 0.00017 22.1 8.0 25 6.0 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK65215.1 - 0.00019 21.0 4.6 6.7 6.5 0.0 6.1 6 0 0 6 6 6 1 TPR repeat Fis1_TPR_C PF14853.6 KIK65215.1 - 0.00025 21.0 6.1 16 5.6 0.0 6.0 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 KIK65215.1 - 0.00082 18.8 5.7 0.59 9.5 0.4 4.4 2 2 2 4 4 4 1 MalT-like TPR region Titin_Ig-rpts PF06582.12 KIK65215.1 - 0.0041 17.0 0.1 2.3 8.2 0.1 4.0 4 0 0 4 4 4 1 Titin repeat TPR_20 PF14561.6 KIK65215.1 - 0.015 15.6 2.8 4 7.8 0.1 4.9 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK65215.1 - 0.016 15.8 10.2 2.3 9.0 0.3 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KIK65215.1 - 0.017 14.7 0.1 3.9 7.0 0.0 4.1 4 1 1 5 5 5 0 Foie gras liver health family 1 Paf67 PF10255.9 KIK65215.1 - 0.039 13.0 0.0 2.4 7.1 0.0 2.8 2 1 0 3 3 3 0 RNA polymerase I-associated factor PAF67 PPR PF01535.20 KIK65215.1 - 0.061 13.6 4.2 3.8 8.0 0.0 4.6 7 0 0 7 7 3 0 PPR repeat DUF3856 PF12968.7 KIK65215.1 - 0.063 13.4 0.9 38 4.3 0.0 4.4 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) WD40 PF00400.32 KIK65219.1 - 5.3e-125 403.7 57.2 7.1e-11 42.5 0.7 11.8 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65219.1 - 3.9e-38 129.6 15.2 0.0028 17.9 0.0 11.0 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK65219.1 - 6.2e-24 84.9 7.9 0.00023 21.1 0.1 6.4 1 1 5 7 7 7 7 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK65219.1 - 7.2e-18 64.6 6.5 0.1 11.5 0.0 10.4 1 1 10 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK65219.1 - 1.7e-13 50.1 20.4 0.79 8.3 0.0 10.0 8 3 2 10 10 10 5 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK65219.1 - 1e-10 41.5 0.1 3.3 7.0 0.0 6.9 6 3 0 6 6 6 3 WD40-like domain PD40 PF07676.12 KIK65219.1 - 1.6e-08 34.3 14.0 39 4.4 0.1 10.9 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK65219.1 - 3.3e-06 26.9 26.2 13 5.7 0.0 10.3 11 0 0 11 11 11 0 Nitrous oxide reductase propeller repeat DsbC_N PF10411.9 KIK65219.1 - 1.6e-05 24.2 4.8 57 3.3 0.0 7.6 9 0 0 9 9 9 0 Disulfide bond isomerase protein N-terminus COPI_C PF06957.11 KIK65219.1 - 3e-05 23.0 0.1 1.4 7.6 0.0 4.4 2 1 3 5 5 5 2 Coatomer (COPI) alpha subunit C-terminus AHJR-like PF18743.1 KIK65219.1 - 0.0027 17.3 0.7 49 3.5 0.0 6.0 2 2 7 9 9 9 0 REase_AHJR-like Imm17 PF15562.6 KIK65219.1 - 0.039 13.8 0.1 72 3.3 0.0 5.1 7 0 0 7 7 6 0 Immunity protein 17 Frtz PF11768.8 KIK65219.1 - 0.08 11.2 0.0 30 2.8 0.0 4.5 4 4 3 7 7 7 0 WD repeat-containing and planar cell polarity effector protein Fritz NHL PF01436.21 KIK65219.1 - 0.18 11.9 20.8 1.5e+02 2.7 0.1 8.8 10 0 0 10 10 10 0 NHL repeat DUF2299 PF10061.9 KIK65219.1 - 0.22 11.3 0.1 3.1e+02 1.0 0.0 5.3 8 0 0 8 8 8 0 Uncharacterized conserved protein (DUF2299) AsnC_trans_reg PF01037.21 KIK65219.1 - 0.3 11.1 1.2 46 4.1 0.0 4.5 6 0 0 6 6 6 0 Lrp/AsnC ligand binding domain DUF5122 PF17164.4 KIK65219.1 - 0.37 11.1 12.6 1.1e+02 3.2 0.1 7.5 9 0 0 9 9 8 0 Domain of unknown function (DUF5122) beta-propeller SymE_toxin PF08845.10 KIK65219.1 - 0.99 9.5 14.1 69 3.6 0.1 6.4 6 0 0 6 6 6 0 Toxin SymE, type I toxin-antitoxin system Big_4 PF07532.11 KIK65219.1 - 2.2 8.1 31.9 5.9 6.7 0.3 7.8 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 4) Fanconi_A PF03511.14 KIK65222.1 - 0.071 13.0 0.7 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Fanconi anaemia group A protein UPF0489 PF12640.7 KIK65222.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SH3_1 PF00018.28 KIK65224.1 - 0.00038 20.0 0.0 0.00075 19.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK65224.1 - 0.042 13.5 0.1 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain Herpes_LMP1 PF05297.11 KIK65224.1 - 0.25 10.5 2.0 0.27 10.4 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DNA_pol_phi PF04931.13 KIK65224.1 - 0.45 8.6 9.1 0.57 8.2 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KIK65224.1 - 1.4 7.1 3.6 1.5 6.9 3.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF508 PF04370.12 KIK65224.1 - 2.5 7.8 5.7 3.7 7.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1645 PF07816.11 KIK65224.1 - 3.2 8.3 9.0 0.19 12.3 2.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) DUF948 PF06103.11 KIK65225.1 - 0.0035 17.6 0.3 0.0065 16.7 0.3 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.13 KIK65225.1 - 0.0038 17.6 0.2 0.046 14.1 0.1 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0184) Baculo_PEP_C PF04513.12 KIK65225.1 - 0.005 16.9 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KIK65225.1 - 0.012 16.1 0.1 0.026 15.0 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 KIK65225.1 - 0.015 15.0 0.6 5.4 6.9 0.0 2.3 1 1 1 2 2 2 0 DASH complex subunit Duo1 IFT57 PF10498.9 KIK65225.1 - 0.02 13.9 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KIK65225.1 - 0.043 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EzrA PF06160.12 KIK65225.1 - 0.14 10.3 0.0 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Hemagglutinin PF00509.18 KIK65225.1 - 0.15 10.5 0.2 0.18 10.2 0.2 1.1 1 0 0 1 1 1 0 Haemagglutinin SesA PF17107.5 KIK65225.1 - 0.15 12.2 0.0 0.97 9.6 0.0 2.1 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RXLR PF16810.5 KIK65226.1 - 0.12 12.8 0.1 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Renin_r PF07850.14 KIK65226.1 - 1.3 9.6 4.3 23 5.7 1.4 2.7 2 0 0 2 2 2 0 Renin receptor-like protein Baculo_PEP_C PF04513.12 KIK65227.1 - 3.2e-05 24.0 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 KIK65227.1 - 0.0085 15.9 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Apolipoprotein PF01442.18 KIK65227.1 - 0.038 13.9 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CdvA PF18822.1 KIK65227.1 - 0.097 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain DUF4349 PF14257.6 KIK65227.1 - 0.1 12.1 0.6 0.15 11.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) BshC PF10079.9 KIK65227.1 - 0.19 10.4 0.3 0.26 10.0 0.3 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC HSBP1 PF06825.12 KIK65227.1 - 1.1 9.1 3.6 3.8 7.5 3.4 1.9 1 1 0 1 1 1 0 Heat shock factor binding protein 1 XhlA PF10779.9 KIK65227.1 - 1.7 8.9 4.6 4.7 7.5 1.3 2.2 1 1 1 2 2 2 0 Haemolysin XhlA IIGP PF05049.13 KIK65228.1 - 1.5e-20 73.7 0.0 3.4e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK65228.1 - 1.7e-06 28.1 0.0 7.1e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK65228.1 - 0.0012 19.4 4.9 0.018 15.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 KIK65228.1 - 0.0016 18.4 0.2 0.0049 16.8 0.0 1.9 3 0 0 3 3 2 1 RsgA GTPase FeoB_N PF02421.18 KIK65228.1 - 0.0022 17.5 0.0 0.0041 16.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 KIK65228.1 - 0.0053 16.5 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain PRK PF00485.18 KIK65228.1 - 0.0054 16.5 3.0 0.0065 16.2 0.0 2.3 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 KIK65228.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 KIK65228.1 - 0.017 14.8 0.0 0.017 14.8 0.0 2.8 3 1 1 4 4 4 0 Guanylate kinase V_ATPase_I PF01496.19 KIK65228.1 - 0.039 11.9 1.7 0.04 11.9 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_15 PF13175.6 KIK65228.1 - 0.091 12.4 0.4 1.8 8.2 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KIK65228.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KIK65228.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.3 3 1 0 3 3 2 0 AAA ATPase domain Dynamin_N PF00350.23 KIK65228.1 - 3.3 7.7 0.0 3.3 7.7 0.0 3.4 3 1 0 3 3 2 0 Dynamin family AAA_22 PF13401.6 KIK65228.1 - 3.8 7.8 7.1 0.48 10.7 0.1 2.9 2 2 0 2 2 1 0 AAA domain Hid1 PF12722.7 KIK65228.1 - 5.6 5.0 12.8 8 4.4 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IIGP PF05049.13 KIK65229.1 - 5.2e-23 81.7 0.1 2.8e-22 79.3 0.1 2.0 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK65229.1 - 1.9e-06 27.9 0.0 5.5e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK65229.1 - 9.4e-05 22.4 0.1 0.0021 18.0 0.0 2.5 3 0 0 3 3 2 1 RsgA GTPase Roc PF08477.13 KIK65229.1 - 0.0002 21.5 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK65229.1 - 0.0032 18.0 0.1 0.0032 18.0 0.1 2.7 2 1 0 2 2 2 1 ABC transporter PRK PF00485.18 KIK65229.1 - 0.0033 17.2 1.0 0.0074 16.0 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Guanylate_kin PF00625.21 KIK65229.1 - 0.011 15.4 1.9 0.028 14.1 0.0 2.6 3 0 0 3 3 3 0 Guanylate kinase AAA_29 PF13555.6 KIK65229.1 - 0.015 15.0 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK65229.1 - 0.022 14.5 1.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TFIIA PF03153.13 KIK65229.1 - 0.044 13.8 6.9 0.065 13.2 6.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 KIK65229.1 - 0.046 14.1 0.0 0.046 14.1 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 KIK65229.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 KIK65229.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KIK65229.1 - 0.1 12.9 3.2 0.31 11.3 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KIK65229.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KIK65229.1 - 0.28 11.7 2.4 4.5 7.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK65229.1 - 0.32 11.5 0.0 0.32 11.5 0.0 3.2 3 1 0 3 3 2 0 AAA domain DDHD PF02862.17 KIK65229.1 - 0.35 11.0 2.8 0.61 10.2 2.8 1.5 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 KIK65229.1 - 2.9 5.7 7.2 4.2 5.1 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynamin_N PF00350.23 KIK65229.1 - 3 7.9 0.0 3 7.9 0.0 3.1 3 1 0 3 3 3 0 Dynamin family PIEZO PF15917.5 KIK65229.1 - 3.3 7.1 11.9 5.6 6.4 11.9 1.3 1 0 0 1 1 1 0 Piezo IIGP PF05049.13 KIK65230.1 - 3.7e-22 78.9 1.8 6.3e-22 78.2 0.0 2.0 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK65230.1 - 2.3e-06 27.6 0.0 7.5e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KIK65230.1 - 0.00057 20.1 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK65230.1 - 0.00062 19.7 0.1 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIK65230.1 - 0.0048 17.4 0.2 0.0048 17.4 0.2 2.8 2 1 0 2 2 2 1 ABC transporter PRK PF00485.18 KIK65230.1 - 0.0051 16.6 1.6 0.0072 16.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 KIK65230.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 KIK65230.1 - 0.043 13.3 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KIK65230.1 - 0.062 13.7 0.0 0.062 13.7 0.0 3.4 3 1 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 KIK65230.1 - 0.092 13.2 0.4 0.092 13.2 0.4 3.4 2 2 0 3 3 2 0 AAA domain Guanylate_kin PF00625.21 KIK65230.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.8 3 1 0 3 3 3 0 Guanylate kinase Viral_helicase1 PF01443.18 KIK65230.1 - 0.17 11.6 0.6 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TFIIA PF03153.13 KIK65230.1 - 0.27 11.2 11.2 0.41 10.6 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_15 PF13175.6 KIK65230.1 - 0.71 9.5 3.4 1.1 8.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIK65230.1 - 1.6 9.0 5.2 0.63 10.3 0.0 2.8 2 2 0 2 2 2 0 AAA domain Hep_59 PF07052.11 KIK65230.1 - 1.9 9.3 22.7 1.9e+03 -0.4 22.7 2.5 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Chs7 PF12271.8 KIK65232.1 - 7.4e-75 252.0 5.1 1e-74 251.5 5.1 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone VEGFR-2_TMD PF17988.1 KIK65232.1 - 0.1 12.0 3.3 0.61 9.6 3.3 2.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Mem_trans PF03547.18 KIK65232.1 - 0.83 8.0 8.6 0.031 12.7 2.7 1.6 2 0 0 2 2 2 0 Membrane transport protein WSC PF01822.19 KIK65233.1 - 2.3e-67 223.2 57.8 1.1e-17 64.0 8.9 4.2 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KIK65233.1 - 1.8e-26 92.8 0.0 1.7e-25 89.6 0.0 2.2 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK65233.1 - 7.9e-23 80.6 0.6 1.9e-22 79.4 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) MFS_1 PF07690.16 KIK65234.1 - 2.6e-35 122.0 33.6 1e-31 110.1 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 KIK65234.1 - 0.00075 18.9 0.6 0.84 9.1 0.1 2.8 2 0 0 2 2 2 2 ATP1G1/PLM/MAT8 family Transgly_assoc PF04226.13 KIK65234.1 - 0.0045 17.2 10.3 0.035 14.4 4.0 3.5 2 0 0 2 2 2 1 Transglycosylase associated protein DUF373 PF04123.13 KIK65234.1 - 6.4 6.1 7.4 1.8 7.9 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Gti1_Pac2 PF09729.9 KIK65235.1 - 8.8e-56 188.9 0.2 5.7e-55 186.2 0.0 2.3 2 1 0 2 2 2 1 Gti1/Pac2 family Terpene_synth_C PF03936.16 KIK65236.1 - 0.0001 21.8 0.2 0.00016 21.1 0.2 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain AAA_lid_7 PF17867.1 KIK65236.1 - 0.045 14.0 0.8 0.41 10.9 0.4 2.2 2 0 0 2 2 2 0 Midasin AAA lid domain Terpene_synth_C PF03936.16 KIK65237.1 - 2.3e-05 23.9 0.0 3.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Sugar_tr PF00083.24 KIK65238.1 - 1.2e-107 360.6 19.0 1.5e-107 360.3 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK65238.1 - 8.6e-24 84.1 34.1 1.4e-19 70.2 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK65238.1 - 0.003 16.1 2.6 0.003 16.1 2.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.12 KIK65238.1 - 4.9 6.8 5.9 1.5 8.5 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF697) MFS_1 PF07690.16 KIK65240.1 - 2.9e-31 108.7 39.2 2.3e-30 105.7 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK65241.1 - 1.4e-35 122.9 40.1 4.1e-34 118.0 34.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily SAC3_GANP PF03399.16 KIK65242.1 - 2e-58 198.1 0.0 2.9e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family PAM2 PF07145.15 KIK65242.1 - 0.0019 17.7 0.5 0.0092 15.6 0.5 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Sfi1 PF08457.10 KIK65242.1 - 0.023 13.3 2.1 0.035 12.6 2.1 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein TAF1D PF15333.6 KIK65242.1 - 0.045 13.5 4.1 0.12 12.1 4.1 1.6 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Antifungal_prot PF11402.8 KIK65244.1 - 0.069 13.4 0.4 0.1 12.8 0.4 1.3 1 1 0 1 1 1 0 Antifungal protein B56 PF01603.20 KIK65245.1 - 0.032 13.2 0.0 0.034 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Terpene_synth_C PF03936.16 KIK65246.1 - 0.0026 17.1 0.0 0.0052 16.2 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain LAP1C PF05609.12 KIK65247.1 - 1.7 7.6 9.8 2.7 7.0 9.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SRP-alpha_N PF04086.13 KIK65247.1 - 3.2 7.6 13.9 5 7.0 13.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peroxidase_2 PF01328.17 KIK65249.1 - 1.8e-29 103.6 0.0 2.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Epimerase PF01370.21 KIK65251.1 - 1.4e-18 67.2 0.1 2.3e-18 66.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK65251.1 - 2.5e-17 62.8 0.4 5.1e-17 61.8 0.4 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK65251.1 - 2.7e-16 60.0 0.1 3e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK65251.1 - 3e-11 43.0 0.2 0.00013 21.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK65251.1 - 1.6e-09 37.6 0.4 3.3e-09 36.6 0.4 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIK65251.1 - 1.1e-08 34.9 0.7 2.1e-08 34.0 0.6 1.4 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIK65251.1 - 1.8e-05 24.0 0.4 0.00011 21.4 0.5 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK65251.1 - 2.2e-05 24.0 0.2 9.2e-05 22.0 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK65251.1 - 3.4e-05 24.1 0.2 4.5e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KIK65251.1 - 0.00016 20.9 0.1 0.00028 20.1 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 KIK65251.1 - 0.0017 18.6 0.1 0.0025 18.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KIK65251.1 - 0.0045 16.9 0.2 0.023 14.6 0.1 2.0 1 1 1 2 2 2 1 KR domain RELT PF12606.8 KIK65251.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 F420_oxidored PF03807.17 KIK65251.1 - 0.013 16.1 0.1 0.027 15.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIK65251.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 KIK65251.1 - 0.047 14.3 0.1 0.1 13.2 0.0 1.7 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KIK65251.1 - 0.062 13.4 0.3 0.14 12.2 0.2 1.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Mid2 PF04478.12 KIK65252.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 2.3 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Rax2 PF12768.7 KIK65252.1 - 0.0031 17.0 0.3 0.0059 16.1 0.3 1.4 1 1 0 1 1 1 1 Cortical protein marker for cell polarity RIFIN PF02009.16 KIK65252.1 - 0.0036 17.2 2.5 0.0064 16.4 2.5 1.4 1 1 0 1 1 1 1 Rifin TMEM154 PF15102.6 KIK65252.1 - 0.0037 17.2 0.4 0.0037 17.2 0.4 2.6 2 0 0 2 2 2 1 TMEM154 protein family Amnionless PF14828.6 KIK65252.1 - 0.005 15.7 0.2 0.014 14.3 0.1 1.7 2 0 0 2 2 2 1 Amnionless Syndecan PF01034.20 KIK65252.1 - 0.0091 15.9 3.7 0.015 15.2 3.7 1.3 1 0 0 1 1 1 1 Syndecan domain Orf78 PF06024.12 KIK65252.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Glycophorin_A PF01102.18 KIK65252.1 - 0.069 13.4 0.0 0.069 13.4 0.0 2.9 3 1 0 3 3 3 0 Glycophorin A DAP10 PF07213.11 KIK65252.1 - 0.086 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein TMEM51 PF15345.6 KIK65252.1 - 0.11 12.3 3.8 0.69 9.7 3.8 2.2 1 1 0 1 1 1 0 Transmembrane protein 51 HemY_N PF07219.13 KIK65252.1 - 0.39 10.9 1.0 1.1 9.5 1.0 1.8 1 1 0 1 1 1 0 HemY protein N-terminus MFS_1 PF07690.16 KIK65255.1 - 3.8e-33 114.9 27.5 3.8e-33 114.9 27.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Trep_Strep PF09605.10 KIK65255.1 - 0.01 15.8 3.1 0.01 15.8 3.1 3.4 3 2 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) FixQ PF05545.11 KIK65255.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Phage_holin_3_6 PF07332.11 KIK65255.1 - 1 9.4 0.0 1 9.4 0.0 3.9 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pyr_redox_2 PF07992.14 KIK65257.1 - 6.1e-29 101.2 0.1 1.9e-28 99.6 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK65257.1 - 2.7e-13 50.3 0.1 3.4e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK65257.1 - 0.00016 21.4 0.0 0.15 11.6 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK65257.1 - 0.00019 20.4 0.4 0.26 10.1 0.0 2.9 2 1 1 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.18 KIK65257.1 - 0.00039 20.7 0.3 0.096 13.0 0.0 3.0 3 0 0 3 3 3 1 TrkA-N domain Pyr_redox_3 PF13738.6 KIK65257.1 - 0.00041 19.7 0.0 0.0066 15.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK65257.1 - 0.00096 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK65257.1 - 0.003 17.5 0.5 8 6.4 0.1 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KIK65257.1 - 0.019 13.7 0.0 7.3 5.2 0.0 2.9 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_4 PF01565.23 KIK65257.1 - 0.043 13.5 0.2 0.9 9.3 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 KIK65257.1 - 0.087 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SET PF00856.28 KIK65258.1 - 7.9e-12 45.9 0.0 4.3e-11 43.5 0.0 2.2 2 1 0 2 2 2 1 SET domain Fer4_14 PF13394.6 KIK65258.1 - 0.21 11.7 1.1 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF3990 PF13151.6 KIK65259.1 - 0.018 14.7 0.0 0.066 12.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3990) Ndc1_Nup PF09531.10 KIK65259.1 - 0.97 8.0 4.3 1.2 7.7 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pyr_redox_2 PF07992.14 KIK65260.1 - 4.2e-26 91.9 1.9 4e-25 88.7 2.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK65260.1 - 8.1e-12 45.5 3.1 1.3e-09 38.5 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK65260.1 - 8.8e-05 21.8 0.9 0.041 13.0 0.2 2.6 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK65260.1 - 0.002 18.1 0.5 6.6 6.7 0.1 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KIK65260.1 - 0.031 14.5 0.1 6.9 7.0 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 KIK65260.1 - 0.68 9.4 3.9 12 5.3 0.0 2.8 2 2 2 4 4 4 0 FAD dependent oxidoreductase Glyco_hydro_35 PF01301.19 KIK65261.1 - 1.1e-73 248.6 0.6 1.8e-73 247.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIK65261.1 - 2e-57 192.7 0.7 1.3e-31 109.5 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIK65261.1 - 3.9e-36 124.6 0.0 6.3e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIK65261.1 - 3.7e-14 52.1 0.0 9.3e-14 50.8 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KIK65261.1 - 0.0072 15.7 0.1 0.14 11.5 0.0 2.5 1 1 1 2 2 2 1 Beta-galactosidase Amidohydro_2 PF04909.14 KIK65261.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase adh_short_C2 PF13561.6 KIK65262.1 - 1.4e-61 208.0 0.7 1.8e-61 207.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK65262.1 - 6.9e-58 195.3 1.4 6.9e-58 195.3 1.4 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK65262.1 - 3.9e-12 46.4 2.7 5.2e-12 46.0 2.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK65262.1 - 0.016 14.7 0.5 0.055 12.9 0.5 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 KIK65262.1 - 0.029 15.0 0.4 0.11 13.1 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain 3HCDH_N PF02737.18 KIK65262.1 - 0.033 14.1 0.3 0.051 13.4 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3226 PF11536.8 KIK65262.1 - 0.035 13.8 0.4 0.048 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) DELLA PF12041.8 KIK65262.1 - 0.15 11.9 0.2 0.57 10.1 0.1 1.9 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal adh_short PF00106.25 KIK65263.1 - 9.5e-51 172.0 0.5 1.5e-50 171.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK65263.1 - 1.4e-50 172.0 0.0 2.1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK65263.1 - 1.3e-09 38.2 1.0 1.9e-09 37.7 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK65263.1 - 0.0018 18.2 0.4 0.0034 17.3 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KIK65264.1 - 9.2e-32 110.3 24.1 1.2e-31 109.9 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK65264.1 - 9.3e-06 25.2 3.2 9.3e-06 25.2 3.2 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2929 PF11151.8 KIK65264.1 - 0.03 14.6 2.0 4.1 7.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) RRM_1 PF00076.22 KIK65265.1 - 6.7e-18 64.3 0.0 9.4e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK65265.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Filament PF00038.21 KIK65266.1 - 0.0031 17.1 2.5 0.0046 16.6 2.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein Yuri_gagarin PF15934.5 KIK65266.1 - 0.0032 17.3 0.3 0.005 16.7 0.3 1.2 1 0 0 1 1 1 1 Yuri gagarin Peptidase_S49_N PF08496.10 KIK65266.1 - 0.0045 17.1 0.1 0.008 16.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Spc7 PF08317.11 KIK65266.1 - 0.0049 15.8 2.6 0.0077 15.2 2.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein UPF0242 PF06785.11 KIK65266.1 - 0.0069 16.5 2.0 0.012 15.8 2.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Sec2p PF06428.11 KIK65266.1 - 0.0083 16.1 1.9 0.0083 16.1 1.9 2.2 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p PKcGMP_CC PF16808.5 KIK65266.1 - 0.011 15.6 2.1 1.9 8.4 0.1 2.6 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 KIK65266.1 - 0.026 14.9 2.6 1.8 8.9 0.3 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 KIK65266.1 - 0.083 12.9 1.0 0.15 12.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KIK65266.1 - 0.1 13.1 3.4 0.19 12.3 3.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region LRS4 PF10422.9 KIK65266.1 - 0.1 12.2 2.1 0.18 11.4 2.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 S1-P1_nuclease PF02265.16 KIK65266.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 S1/P1 Nuclease YlqD PF11068.8 KIK65266.1 - 0.17 12.3 7.9 0.06 13.7 5.2 1.5 2 0 0 2 2 1 0 YlqD protein Bacillus_HBL PF05791.11 KIK65266.1 - 0.2 11.5 5.1 6.5 6.5 2.3 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TBCA PF02970.16 KIK65266.1 - 0.26 11.7 1.6 0.45 10.9 1.6 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A CC2-LZ PF16516.5 KIK65266.1 - 0.33 11.3 6.0 1.3 9.4 6.0 1.8 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.6 KIK65266.1 - 0.55 9.5 2.2 2.6 7.3 2.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Med9 PF07544.13 KIK65266.1 - 0.75 9.9 4.6 9.6 6.4 4.6 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TolA_bind_tri PF16331.5 KIK65266.1 - 1.1 9.3 4.3 12 6.1 4.3 2.3 1 1 0 1 1 1 0 TolA binding protein trimerisation Csm1_N PF18504.1 KIK65266.1 - 1.3 9.4 6.5 15 6.0 2.1 2.4 1 1 0 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 KIK65266.1 - 2.6 8.3 4.8 19 5.6 4.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF745 PF05335.13 KIK65267.1 - 0.11 12.2 1.0 6.2 6.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) GMC_oxred_N PF00732.19 KIK65269.1 - 4.7e-61 206.7 0.0 6.5e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK65269.1 - 6.9e-31 107.7 0.0 1.4e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK65269.1 - 0.00067 18.8 0.6 0.0011 18.1 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DUF4516 PF14990.6 KIK65270.1 - 0.73 9.6 2.5 0.93 9.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) DUF2953 PF11167.8 KIK65270.1 - 1.2 9.3 4.6 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) DUF5107 PF17128.4 KIK65271.1 - 0.19 10.9 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) ASPRs PF17641.2 KIK65272.1 - 0.0043 17.3 1.3 0.0061 16.8 0.3 1.8 2 0 0 2 2 2 1 Ancylostoma-associated secreted protein related TRI5 PF06330.11 KIK65274.1 - 0.00017 20.5 0.1 0.00025 20.0 0.1 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 KIK65274.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain p450 PF00067.22 KIK65275.1 - 6.7e-66 222.9 0.0 8.9e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 KIK65276.1 - 2.4e-17 62.6 0.1 1e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK65276.1 - 8.4e-16 58.0 0.0 3.7e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK65276.1 - 5.9e-12 45.4 0.0 1.9e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK65276.1 - 4.5e-10 39.6 0.1 1.1e-08 35.2 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK65276.1 - 1.7e-08 34.1 0.0 3e-07 30.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK65276.1 - 1.4e-07 31.9 0.2 0.002 18.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK65276.1 - 5.4e-06 26.2 2.9 0.0027 17.3 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK65276.1 - 0.00011 22.2 3.2 0.073 13.1 0.1 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KIK65276.1 - 0.00073 18.3 0.6 0.0053 15.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KIK65276.1 - 0.00085 18.5 0.1 0.019 14.1 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK65276.1 - 0.003 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KIK65276.1 - 0.0064 15.8 0.0 0.97 8.7 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK65276.1 - 0.017 14.4 0.4 0.052 12.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KIK65276.1 - 0.024 13.7 0.0 0.065 12.3 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KIK65276.1 - 0.11 13.0 0.0 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIK65276.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK65276.1 - 0.21 11.7 0.0 7.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KIK65276.1 - 0.84 8.6 2.5 0.48 9.4 0.1 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_4 PF01565.23 KIK65277.1 - 8.9e-27 93.5 0.7 1.7e-26 92.6 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK65277.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.22 KIK65278.1 - 3.9e-61 207.2 0.0 4.9e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2620 PF10941.8 KIK65279.1 - 0.12 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 T_cell_tran_alt PF15128.6 KIK65279.1 - 4.8 7.0 5.4 9.4 6.1 0.1 3.3 3 1 0 3 3 3 0 T-cell leukemia translocation-altered HSP90 PF00183.18 KIK65280.1 - 4.4e-137 458.1 0.0 5.7e-137 457.7 0.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 KIK65280.1 - 5.6e-08 32.7 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK65280.1 - 5.4e-05 23.7 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_28 PF13521.6 KIK65280.1 - 0.049 13.9 0.2 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Latarcin PF10279.9 KIK65280.1 - 0.06 13.7 0.6 0.24 11.8 0.6 2.1 1 0 0 1 1 1 0 Latarcin precursor TEX19 PF15553.6 KIK65281.1 - 6.4 6.7 5.7 6.8 6.6 0.3 2.5 2 0 0 2 2 2 0 Testis-expressed protein 19 Kelch_4 PF13418.6 KIK65282.1 - 5e-16 58.4 10.9 0.0081 16.2 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KIK65282.1 - 1.9e-13 50.3 25.1 0.0043 17.3 0.2 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK65282.1 - 1.5e-08 34.6 7.0 0.019 15.2 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KIK65282.1 - 2.7e-07 30.4 4.5 0.21 11.6 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KIK65282.1 - 0.00021 20.8 6.6 1.6 8.4 0.1 5.2 5 0 0 5 5 5 2 Kelch motif HEAT PF02985.22 KIK65282.1 - 0.13 12.6 0.0 0.84 10.1 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat Fig1 PF12351.8 KIK65282.1 - 1.7 8.6 7.4 7.3 6.5 1.5 2.4 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 G3P_acyltransf PF02660.15 KIK65282.1 - 2.1 8.4 10.7 0.15 12.1 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase RNR_inhib PF08591.10 KIK65283.1 - 2.8e-05 25.4 4.2 9.9e-05 23.6 4.2 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor zf-H2C2_2 PF13465.6 KIK65284.1 - 1.1e-06 28.8 13.2 0.00027 21.2 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KIK65284.1 - 9.4e-06 25.8 15.3 0.0047 17.3 0.9 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK65284.1 - 5.7e-05 23.6 17.4 0.0045 17.7 0.9 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KIK65284.1 - 0.13 12.7 1.5 0.25 11.8 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 KIK65284.1 - 0.95 8.6 6.6 1.5 7.9 0.5 2.1 1 1 1 2 2 2 0 Putative actin-like family FOXP-CC PF16159.5 KIK65284.1 - 3.2 8.5 9.6 5.6 7.7 0.5 3.6 2 1 2 4 4 4 0 FOXP coiled-coil domain Cid2 PF09774.9 KIK65285.1 - 2.3e-25 89.9 8.5 4.9e-25 88.8 8.5 1.5 1 1 0 1 1 1 1 Caffeine-induced death protein 2 GILT PF03227.16 KIK65286.1 - 1.2e-18 67.3 0.5 2e-18 66.6 0.5 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) UQ_con PF00179.26 KIK65287.1 - 2.5e-23 82.3 0.0 4.5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 KIK65287.1 - 0.0002 21.5 3.2 0.0005 20.3 3.2 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain UBA PF00627.31 KIK65287.1 - 0.0014 18.5 1.3 0.003 17.4 1.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Mito_carr PF00153.27 KIK65288.1 - 5.3e-47 157.7 8.3 2e-16 59.7 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KIK65288.1 - 0.025 14.7 0.1 0.73 10.0 0.1 2.4 2 0 0 2 2 2 0 PrcB C-terminal HMD PF03201.16 KIK65288.1 - 0.049 13.8 0.1 8 6.8 0.0 3.3 2 1 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Sedlin_N PF04628.13 KIK65289.1 - 5.1e-20 71.9 0.0 6.5e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RTP1_C1 PF10363.9 KIK65290.1 - 1.1e-35 122.2 1.7 1.5e-33 115.3 0.3 3.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KIK65290.1 - 1.1e-05 25.2 2.6 0.55 10.6 0.1 5.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KIK65290.1 - 0.0005 20.4 4.7 2.9 8.4 0.1 5.2 5 0 0 5 5 5 2 HEAT repeats UNC45-central PF11701.8 KIK65290.1 - 0.019 14.9 0.1 1.6 8.7 0.0 2.8 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KIK65290.1 - 0.11 13.0 0.1 3.7 8.2 0.0 3.8 2 0 0 2 2 2 0 HEAT-like repeat AA_permease_2 PF13520.6 KIK65291.1 - 1.8e-48 165.5 58.4 2.3e-48 165.1 58.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK65291.1 - 2.9e-20 72.3 51.1 3.7e-20 72.0 51.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2645 PF10840.8 KIK65291.1 - 0.041 14.5 3.5 0.041 14.5 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) GTP_EFTU PF00009.27 KIK65292.1 - 1.1e-44 152.4 0.0 1.4e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK65292.1 - 5e-35 120.2 0.1 2.6e-34 117.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIK65292.1 - 8e-10 39.0 0.1 1.8e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK65292.1 - 0.0018 18.3 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PRCC PF10253.9 KIK65292.1 - 0.48 11.2 4.7 0.75 10.5 4.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SH3_9 PF14604.6 KIK65293.1 - 1.6e-39 133.5 5.0 1.5e-14 53.6 0.2 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 KIK65293.1 - 3.3e-34 116.2 6.2 3.3e-14 52.2 0.2 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KIK65293.1 - 3e-29 100.7 0.0 6.1e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KIK65293.1 - 5.4e-21 74.0 0.0 3.2e-06 26.7 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 KIK65293.1 - 4.6e-05 23.4 0.3 0.18 11.9 0.0 3.8 4 0 0 4 4 4 1 SH3 domain SH3_3 PF08239.11 KIK65293.1 - 0.00015 22.0 0.3 0.7 10.2 0.1 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain DUF1720 PF08226.11 KIK65293.1 - 0.00028 21.2 24.0 0.00028 21.2 24.0 5.7 2 2 3 5 5 4 2 Domain of unknown function (DUF1720) hSH3 PF14603.6 KIK65293.1 - 0.0031 17.9 0.0 0.023 15.1 0.0 2.4 3 0 0 3 3 3 1 Helically-extended SH3 domain SAM_4 PF18017.1 KIK65293.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIK65293.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CDC45 PF02724.14 KIK65293.1 - 0.15 10.3 10.9 0.22 9.8 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PCM1_C PF15717.5 KIK65293.1 - 0.25 10.0 8.2 0.39 9.3 8.2 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus SDA1 PF05285.12 KIK65293.1 - 0.6 9.5 17.2 1.4 8.3 17.2 1.5 1 0 0 1 1 1 0 SDA1 Coilin_N PF15862.5 KIK65293.1 - 6.5 6.6 7.5 12 5.7 5.2 2.2 2 0 0 2 2 2 0 Coilin N-terminus RNA_polI_A34 PF08208.11 KIK65293.1 - 7 6.7 20.8 29 4.6 20.8 2.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF966 PF06136.13 KIK65293.1 - 7.3 6.2 10.9 15 5.2 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Sec7 PF01369.20 KIK65294.1 - 1.6e-74 249.6 0.1 3.5e-74 248.5 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KIK65294.1 - 5.4e-45 153.1 3.0 5.4e-45 153.1 3.0 3.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIK65294.1 - 3.1e-33 113.5 0.9 3.1e-33 113.5 0.9 5.2 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KIK65294.1 - 6.7e-24 84.5 2.4 2.8e-21 76.0 0.2 3.3 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 KIK65294.1 - 0.054 13.6 0.2 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Aldolase_II PF00596.21 KIK65295.1 - 3.2e-42 144.6 0.2 4e-42 144.2 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2478 PF10649.9 KIK65295.1 - 0.049 13.3 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Zf_RING PF16744.5 KIK65296.1 - 0.097 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KIK65296.1 - 0.11 12.8 0.7 0.28 11.5 0.7 1.7 1 1 0 1 1 1 0 Ring finger domain NR_Repeat PF14046.6 KIK65296.1 - 0.39 10.9 0.1 0.39 10.9 0.1 2.8 3 0 0 3 3 3 0 Nuclear receptor repeat zf-RING_2 PF13639.6 KIK65297.1 - 4.1e-08 33.4 6.0 6.7e-07 29.5 3.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIK65297.1 - 1.3e-06 28.6 0.6 1.3e-06 28.6 0.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIK65297.1 - 3.1e-05 23.6 1.9 0.0012 18.6 0.4 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KIK65297.1 - 7.2e-05 22.6 0.9 7.2e-05 22.6 0.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIK65297.1 - 0.0001 21.8 0.3 0.00025 20.6 0.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KIK65297.1 - 0.00018 21.3 2.5 0.00047 19.9 0.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK65297.1 - 0.00037 20.4 0.7 0.00037 20.4 0.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK65297.1 - 0.00042 20.1 3.2 0.00042 20.1 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK65297.1 - 0.001 19.1 0.2 0.0022 18.0 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIK65297.1 - 0.0038 17.0 1.9 0.0093 15.8 0.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK65297.1 - 0.0047 16.9 2.9 0.0087 16.0 0.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 KIK65297.1 - 0.039 14.0 2.0 0.092 12.8 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 KIK65297.1 - 0.19 11.9 0.4 0.45 10.7 0.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KIK65297.1 - 0.43 10.8 2.2 1 9.6 0.2 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KIK65297.1 - 0.67 10.1 4.8 0.093 12.9 0.7 1.7 2 0 0 2 2 1 0 RING-variant domain DS PF01916.17 KIK65298.1 - 2.8e-135 450.2 0.0 3.2e-135 450.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.20 KIK65299.1 - 5e-56 189.7 0.4 5.5e-56 189.5 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Aminotran_1_2 PF00155.21 KIK65300.1 - 1.5e-20 73.7 0.0 1.5e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II zf-CCHC PF00098.23 KIK65301.1 - 4.6e-26 89.7 30.0 5.3e-09 35.8 2.3 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 KIK65301.1 - 4.3e-08 32.8 16.9 0.056 13.2 0.4 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 KIK65301.1 - 0.032 14.2 23.9 0.27 11.2 1.7 4.2 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIK65301.1 - 0.1 12.3 16.3 0.39 10.5 0.4 4.3 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 KIK65301.1 - 0.31 11.4 20.9 0.42 11.0 1.0 2.9 2 1 1 3 3 3 0 DnaJ central domain TRAF6_Z2 PF18048.1 KIK65301.1 - 2.5 8.3 7.2 0.97 9.6 0.6 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Polyketide_cyc PF03364.20 KIK65302.1 - 7.2e-24 84.4 0.1 8.8e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GST_N_3 PF13417.6 KIK65304.1 - 1.3e-07 31.9 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK65304.1 - 0.00024 21.2 0.1 0.0011 19.1 0.0 1.9 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK65304.1 - 0.0015 18.7 0.1 0.0059 16.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Chitin_synth_1 PF01644.17 KIK65305.1 - 2e-67 226.2 0.1 3.2e-67 225.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK65305.1 - 2e-29 101.4 0.2 4.6e-29 100.2 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK65305.1 - 1.7e-22 79.7 0.1 5.5e-19 68.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK65305.1 - 5.3e-08 33.0 6.7 5.4e-07 29.7 6.7 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 zf-RING_2 PF13639.6 KIK65306.1 - 1.7e-05 25.1 5.0 0.0001 22.6 2.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK65306.1 - 0.00013 21.7 5.6 0.00029 20.6 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK65306.1 - 0.00017 21.4 5.4 0.0026 17.6 6.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK65306.1 - 0.0002 21.1 3.7 0.001 18.9 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK65306.1 - 0.00021 21.1 3.5 0.0062 16.5 2.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIK65306.1 - 0.00057 20.1 2.7 0.0015 18.7 0.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C2HC5 PF06221.13 KIK65306.1 - 0.0034 17.3 0.4 0.053 13.5 0.1 2.2 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type Prok-RING_4 PF14447.6 KIK65306.1 - 0.0036 17.1 6.0 0.01 15.7 1.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIK65306.1 - 0.015 15.1 2.8 0.17 11.7 2.8 2.2 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 KIK65306.1 - 0.028 14.7 3.2 0.37 11.1 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon Auto_anti-p27 PF06677.12 KIK65306.1 - 0.029 14.5 1.3 7.7 6.8 0.2 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_4 PF15227.6 KIK65306.1 - 0.049 13.8 1.5 0.049 13.8 1.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIK65306.1 - 0.056 13.2 4.8 0.084 12.7 1.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KIK65306.1 - 0.082 12.9 5.7 0.4 10.7 5.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KIK65306.1 - 0.084 12.8 0.4 3.3 7.7 0.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF2996 PF11210.8 KIK65306.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) zf-P11 PF03854.14 KIK65306.1 - 0.35 10.6 4.0 4.3 7.1 0.6 2.2 2 0 0 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.14 KIK65306.1 - 1.7 8.5 5.6 1.4 8.8 0.4 2.6 2 1 0 2 2 2 0 Rad50 zinc hook motif Spo12 PF05032.12 KIK65307.1 - 1.5e-14 53.5 1.0 2.8e-14 52.7 1.0 1.5 1 0 0 1 1 1 1 Spo12 family LAX PF15681.5 KIK65307.1 - 0.022 13.6 0.7 0.03 13.2 0.7 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X DUF1726 PF08351.11 KIK65307.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) BH3 PF15285.6 KIK65308.1 - 0.093 12.5 0.3 0.29 11.0 0.3 1.9 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Ras PF00071.22 KIK65309.1 - 3.5e-36 124.3 0.2 5.3e-36 123.7 0.2 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KIK65309.1 - 4.3e-10 39.8 0.0 2.5e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK65309.1 - 1.7e-05 24.8 0.0 0.066 13.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KIK65309.1 - 0.006 16.6 0.0 0.0091 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK65309.1 - 0.019 14.9 0.4 0.023 14.6 0.4 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Arf PF00025.21 KIK65309.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family FeoB_N PF02421.18 KIK65309.1 - 0.049 13.2 0.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KIK65309.1 - 0.054 13.6 0.0 0.072 13.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mannosidase_ig PF17786.1 KIK65310.1 - 2.3e-12 47.3 0.1 7.2e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIK65310.1 - 8.8e-09 36.0 0.0 5.2e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KIK65310.1 - 1.5e-05 24.9 0.1 7.5e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KIK65310.1 - 0.0053 16.5 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Ig-fold domain SMC_N PF02463.19 KIK65311.1 - 3.4e-20 72.5 2.7 1e-19 70.9 2.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK65311.1 - 1.5e-15 57.8 18.0 1.2e-13 51.6 0.0 3.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 KIK65311.1 - 7.1e-07 29.9 31.0 7.1e-07 29.9 31.0 6.7 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.6 KIK65311.1 - 0.00052 19.7 0.0 0.0039 16.9 0.0 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK65311.1 - 0.0016 18.3 0.1 0.0016 18.3 0.1 3.2 3 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KIK65311.1 - 0.52 9.9 4.4 1.4 8.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KIK65311.1 - 0.7 10.3 0.0 0.7 10.3 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK65311.1 - 0.75 10.3 0.0 0.75 10.3 0.0 5.4 3 2 0 4 4 4 0 ABC transporter DUF2937 PF11157.8 KIK65311.1 - 0.93 9.2 0.0 0.93 9.2 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2937) MFS_1 PF07690.16 KIK65313.1 - 4.3e-34 118.0 26.0 6.2e-34 117.5 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF997 PF06196.12 KIK65313.1 - 5.6 7.0 9.8 1.9 8.5 3.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) tRNA-synt_2c PF01411.19 KIK65314.1 - 8.5e-07 27.9 0.0 1.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIK65314.1 - 0.00027 21.0 0.0 0.00074 19.6 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.16 KIK65315.1 - 1.7e-39 135.7 33.2 9.3e-34 116.9 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CK_II_beta PF01214.18 KIK65316.1 - 3.8e-79 264.7 0.0 4.6e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SYCP2_SLD PF18584.1 KIK65316.1 - 0.13 12.5 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain RRM_1 PF00076.22 KIK65317.1 - 7.8e-17 60.9 0.0 2.6e-07 30.3 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK65317.1 - 0.0047 16.7 0.1 0.7 9.8 0.0 2.4 2 1 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KIK65317.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF809 PF05663.11 KIK65317.1 - 0.18 11.9 0.1 0.55 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) CENP-B_dimeris PF09026.10 KIK65317.1 - 0.7 10.3 6.4 1.3 9.4 6.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KIK65317.1 - 0.97 7.4 4.4 1.3 7.0 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAM_LAG1_CLN8 PF03798.16 KIK65318.1 - 4.8e-42 144.0 17.6 6.8e-42 143.5 17.6 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KIK65318.1 - 3.6e-08 32.9 0.0 1.2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 TRAM1-like protein Snf7 PF03357.21 KIK65319.1 - 1.6e-34 119.0 20.4 1.9e-34 118.7 20.4 1.2 1 0 0 1 1 1 1 Snf7 DUF29 PF01724.16 KIK65319.1 - 0.94 9.7 6.6 2.7 8.2 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF29 Ribosomal_60s PF00428.19 KIK65319.1 - 1.4 9.6 8.9 3.5 8.3 1.3 3.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein NIF PF03031.18 KIK65320.1 - 7.1e-52 175.3 0.0 9.7e-52 174.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ASXH PF13919.6 KIK65321.1 - 2.5e-21 76.1 3.7 1.2e-19 70.7 0.6 2.3 2 0 0 2 2 2 2 Asx homology domain Peptidase_C12 PF01088.21 KIK65322.1 - 5.4e-54 183.1 0.0 8.9e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KIK65322.1 - 1.4e-09 37.7 1.0 7.6e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Mob1_phocein PF03637.17 KIK65323.1 - 3e-79 264.9 0.0 3.5e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family BTB PF00651.31 KIK65324.1 - 0.037 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DEAD PF00270.29 KIK65325.1 - 1e-40 139.3 0.0 1.8e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK65325.1 - 2.4e-24 85.8 0.0 6.2e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK65325.1 - 0.0035 17.4 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK65325.1 - 0.034 14.4 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain SulA PF03846.14 KIK65325.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Cell division inhibitor SulA DUF302 PF03625.14 KIK65326.1 - 0.0011 18.8 0.4 0.0022 17.8 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function DUF302 Trimer_CC PF08954.11 KIK65326.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif HMG_box PF00505.19 KIK65327.1 - 4.5e-13 49.4 1.8 6.3e-13 48.9 1.8 1.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK65327.1 - 8e-05 23.2 1.1 0.00017 22.1 1.1 1.6 1 1 0 1 1 1 1 HMG-box domain DUF3106 PF11304.8 KIK65327.1 - 0.013 15.9 0.5 0.016 15.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Sua5_yciO_yrdC PF01300.18 KIK65328.1 - 8.3e-52 175.3 0.0 2.4e-51 173.8 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 KIK65328.1 - 1.9e-29 102.9 0.0 2.9e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DMRT-like PF15791.5 KIK65328.1 - 0.062 13.7 1.2 11 6.5 0.1 2.6 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Complex1_LYR_2 PF13233.6 KIK65329.1 - 7.5e-16 58.7 0.2 8.8e-16 58.4 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.22 KIK65330.1 - 0.00013 21.7 0.0 0.0079 16.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Wbp11 PF09429.10 KIK65330.1 - 0.087 13.2 1.7 0.15 12.5 1.7 1.4 1 0 0 1 1 1 0 WW domain binding protein 11 DEAD PF00270.29 KIK65331.1 - 1e-18 67.7 0.0 1.7e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK65331.1 - 0.037 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain WD40 PF00400.32 KIK65332.1 - 2.2e-37 126.4 21.5 7.2e-05 23.5 0.2 11.0 9 1 1 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65332.1 - 1.2e-11 44.8 1.2 0.17 12.2 0.0 7.4 5 2 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KIK65332.1 - 0.011 15.8 0.0 10 6.2 0.0 3.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KIK65332.1 - 0.031 13.2 0.8 1 8.3 0.2 3.3 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK65332.1 - 0.35 10.6 2.4 0.88 9.3 0.2 2.7 4 0 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain ACPS PF01648.20 KIK65333.1 - 2e-15 56.9 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF3918 PF13056.6 KIK65333.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GCV_T PF01571.21 KIK65334.1 - 0.0028 17.0 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GST_N PF02798.20 KIK65335.1 - 6.7e-12 45.6 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK65335.1 - 2.5e-11 43.6 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK65335.1 - 3.4e-10 40.2 0.0 5.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK65335.1 - 1.7e-08 34.6 0.0 3.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK65335.1 - 4.1e-05 23.7 0.0 0.00016 21.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK65335.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldolase_II PF00596.21 KIK65336.1 - 7.4e-43 146.6 0.2 9.2e-43 146.3 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2478 PF10649.9 KIK65336.1 - 0.045 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) MFS_1 PF07690.16 KIK65337.1 - 3.6e-35 121.5 27.1 3.6e-35 121.5 27.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1640 PF07798.11 KIK65338.1 - 3.4e-44 151.0 1.9 4.5e-44 150.6 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Med11 PF10280.9 KIK65338.1 - 2.8e-05 24.6 0.1 7.7e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Mediator complex protein Fzo_mitofusin PF04799.13 KIK65338.1 - 0.074 12.6 1.3 0.14 11.7 1.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region Mago-bind PF09282.10 KIK65339.1 - 2.2e-14 53.0 3.4 3.8e-14 52.2 3.4 1.4 1 0 0 1 1 1 1 Mago binding ATP_bind_1 PF03029.17 KIK65340.1 - 2.7e-77 259.8 0.0 3.4e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KIK65340.1 - 0.00073 20.0 0.0 0.0061 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK65340.1 - 0.00099 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 KIK65340.1 - 0.0037 16.6 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KIK65340.1 - 0.0043 16.8 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK65340.1 - 0.0052 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIK65340.1 - 0.0064 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF463 PF04317.12 KIK65340.1 - 0.0065 15.5 0.0 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 YcjX-like family, DUF463 T2SSE PF00437.20 KIK65340.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KIK65340.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KIK65340.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK65340.1 - 0.013 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KIK65340.1 - 0.013 15.6 0.1 0.034 14.2 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 KIK65340.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 KIK65340.1 - 0.015 15.8 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK65340.1 - 0.025 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK65340.1 - 0.029 14.0 0.1 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KIK65340.1 - 0.036 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KIK65340.1 - 0.042 13.6 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK65340.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CLP1_P PF16575.5 KIK65340.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 KIK65340.1 - 0.054 13.4 0.1 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 NTPase ArsA_ATPase PF02374.15 KIK65340.1 - 0.056 12.6 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_10 PF12846.7 KIK65340.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.10 KIK65340.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 KIK65340.1 - 0.09 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CobU PF02283.16 KIK65340.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Zeta_toxin PF06414.12 KIK65340.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KIK65340.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KIK65340.1 - 0.16 11.9 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 KIK65340.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK65340.1 - 0.23 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Dynamin_N PF00350.23 KIK65342.1 - 1e-11 45.2 1.1 5.7e-10 39.5 0.1 3.4 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KIK65342.1 - 3.7e-07 30.2 0.1 0.001 19.1 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KIK65342.1 - 5.4e-07 30.3 0.1 5.4e-07 30.3 0.1 3.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KIK65342.1 - 8.9e-05 23.0 0.1 0.00043 20.8 0.1 2.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK65342.1 - 0.00052 19.9 1.2 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIK65342.1 - 0.00085 19.6 0.1 0.012 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIK65342.1 - 0.0017 18.1 5.4 0.034 13.9 0.1 3.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_27 PF13514.6 KIK65342.1 - 0.0039 16.8 0.6 0.34 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIK65342.1 - 0.0084 15.2 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIK65342.1 - 0.019 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KIK65342.1 - 0.022 14.1 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin FeoB_N PF02421.18 KIK65342.1 - 0.028 13.9 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KIK65342.1 - 0.033 13.9 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK65342.1 - 0.035 14.5 0.9 0.41 11.0 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain ADIP PF11559.8 KIK65342.1 - 0.14 12.2 9.4 0.8 9.8 2.8 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CHD5 PF04420.14 KIK65342.1 - 0.15 11.9 1.4 0.42 10.5 1.4 1.7 1 0 0 1 1 1 0 CHD5-like protein ZapB PF06005.12 KIK65342.1 - 2.9 8.4 6.1 52 4.4 4.4 3.4 2 1 0 2 2 2 0 Cell division protein ZapB CHASE3 PF05227.13 KIK65342.1 - 3.7 7.5 8.3 0.37 10.7 0.2 3.0 3 0 0 3 3 2 0 CHASE3 domain DivIC PF04977.15 KIK65342.1 - 7.1 6.5 6.3 12 5.7 1.0 3.0 1 1 1 2 2 2 0 Septum formation initiator DUF2838 PF10998.8 KIK65344.1 - 2.3e-41 140.5 8.8 4.9e-41 139.4 8.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) DUF1640 PF07798.11 KIK65344.1 - 0.12 12.4 2.5 0.23 11.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) MFS_1 PF07690.16 KIK65345.1 - 2.4e-35 122.1 24.0 3.3e-35 121.7 24.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.6 KIK65345.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Thiolase_N PF00108.23 KIK65346.1 - 4e-86 288.6 1.5 5.8e-86 288.0 1.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK65346.1 - 2.5e-40 136.9 0.6 2.5e-40 136.9 0.6 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK65346.1 - 0.0026 17.4 4.2 0.0026 17.4 4.2 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Autophagy_act_C PF03987.15 KIK65347.1 - 6.7e-19 68.2 0.2 1.2e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.18 KIK65348.1 - 6.8e-94 313.1 2.6 8.4e-94 312.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KIK65348.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region MRP-L27 PF09809.9 KIK65348.1 - 0.057 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 TipAS PF07739.13 KIK65348.1 - 0.17 12.5 0.1 1.3 9.5 0.0 2.3 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Pribosyltran PF00156.27 KIK65349.1 - 4.1e-13 49.1 0.1 5.2e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIK65349.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 KIK65350.1 - 2.5e-111 372.8 0.0 4e-111 372.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KIK65350.1 - 6.5e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PA domain VWA_3_C PF18571.1 KIK65350.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain Auto_anti-p27 PF06677.12 KIK65351.1 - 2.7e-22 78.6 1.8 4.2e-12 46.0 0.4 2.7 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribonuclease_3 PF00636.26 KIK65355.1 - 1.6e-34 118.7 0.0 1.2e-15 58.0 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK65355.1 - 2.4e-22 79.5 0.7 1.8e-07 31.3 0.1 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like Helicase_C PF00271.31 KIK65355.1 - 4.1e-05 23.9 0.2 0.0002 21.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 KIK65355.1 - 4.9e-05 23.4 0.0 0.00037 20.6 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain PAZ PF02170.22 KIK65355.1 - 0.0004 20.2 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.16 KIK65356.1 - 8.6e-18 64.4 0.9 1e-17 64.1 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Adeno_E3 PF06040.11 KIK65356.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus E3 protein Aldedh PF00171.22 KIK65357.1 - 1e-176 588.0 0.2 1.3e-176 587.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.18 KIK65358.1 - 2e-07 31.0 10.8 2e-07 31.0 10.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KIK65359.1 - 3e-60 203.0 0.0 4.9e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK65359.1 - 2.5e-08 33.4 0.2 7.5e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ssu72 PF04722.13 KIK65360.1 - 7.9e-83 276.7 0.0 1.1e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein F-box-like PF12937.7 KIK65361.1 - 5.7e-06 26.1 0.5 5.7e-06 26.1 0.5 3.0 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 KIK65361.1 - 0.11 12.9 3.8 11 6.6 0.1 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK65361.1 - 0.14 12.3 1.6 18 5.7 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Syntaxin-18_N PF10496.9 KIK65362.1 - 6.9e-16 58.3 2.5 6.9e-16 58.3 2.5 3.6 3 2 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KIK65362.1 - 0.1 12.6 2.8 0.12 12.4 0.0 2.5 3 0 0 3 3 3 0 SNARE domain VPS13_C PF16909.5 KIK65362.1 - 0.17 11.6 1.5 7.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal SNARE_assoc PF09335.11 KIK65363.1 - 1.3e-17 64.4 5.3 1.3e-17 64.4 5.3 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein Cyclin_C PF02984.19 KIK65363.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain CD34_antigen PF06365.12 KIK65363.1 - 0.16 11.6 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF2304 PF10066.9 KIK65363.1 - 1.7 8.9 11.5 1.9 8.8 8.5 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MpPF26 PF07666.11 KIK65363.1 - 6.2 7.0 12.7 0.25 11.4 0.8 2.6 2 1 1 3 3 3 0 M penetrans paralogue family 26 Tetraspanin PF00335.20 KIK65363.1 - 8.1 6.1 9.8 7.8 6.1 8.3 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF973 PF06157.11 KIK65364.1 - 0.071 12.1 4.1 0.11 11.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Cys_Met_Meta_PP PF01053.20 KIK65365.1 - 1.2e-52 178.7 0.0 4.6e-52 176.8 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ATP_transf PF09830.9 KIK65365.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP adenylyltransferase Fungal_trans PF04082.18 KIK65366.1 - 7.5e-16 58.0 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK65366.1 - 0.002 18.2 4.6 0.0044 17.1 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIRP PF06584.13 KIK65366.1 - 0.062 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 DIRP Vezatin PF12632.7 KIK65366.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DPBB_1 PF03330.18 KIK65367.1 - 9.5e-06 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase WD40 PF00400.32 KIK65368.1 - 7.1e-52 172.2 23.4 1.1e-07 32.4 0.0 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65368.1 - 5.5e-23 81.1 4.8 7.4e-05 23.0 0.0 9.4 4 3 5 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KIK65368.1 - 1.3e-20 73.7 1.5 2.3e-20 72.9 1.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KIK65368.1 - 2e-08 33.6 12.8 0.023 13.7 0.1 6.1 3 2 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK65368.1 - 1.1e-07 30.9 4.1 0.071 11.7 0.4 5.0 5 1 0 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK65368.1 - 8.3e-05 22.1 0.2 1.6 8.0 0.0 4.3 4 1 1 5 5 5 2 WD40-like domain eIF2A PF08662.11 KIK65368.1 - 0.0098 15.8 0.8 8.1 6.3 0.0 4.2 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 KIK65368.1 - 0.013 14.8 0.2 0.31 10.2 0.0 3.0 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 KIK65368.1 - 0.046 12.5 4.6 0.42 9.3 0.1 4.1 3 2 2 6 6 6 0 Nup133 N terminal like Peptidase_M18 PF02127.15 KIK65369.1 - 4.2e-155 516.8 0.0 4.8e-155 516.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Brix PF04427.18 KIK65370.1 - 3.1e-32 112.3 0.6 4.2e-32 111.8 0.6 1.2 1 0 0 1 1 1 1 Brix domain Alg6_Alg8 PF03155.15 KIK65371.1 - 6.6e-168 559.6 29.0 7.6e-168 559.4 29.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family VMA21 PF09446.10 KIK65372.1 - 1.4e-10 41.1 7.3 1.9e-10 40.7 7.3 1.2 1 0 0 1 1 1 1 VMA21-like domain ATE_C PF04377.15 KIK65374.1 - 9.5e-44 149.3 0.9 9.5e-44 149.3 0.9 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KIK65374.1 - 2.6e-24 85.4 0.8 2.6e-24 85.4 0.8 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KIK65374.1 - 0.062 13.5 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 KIK65375.1 - 0.00047 20.9 0.0 0.025 15.5 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65375.1 - 0.0019 18.4 0.0 1.2 9.5 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF839 PF05787.13 KIK65375.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) EF-hand_7 PF13499.6 KIK65377.1 - 2e-25 89.0 9.1 1.7e-17 63.6 1.8 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIK65377.1 - 6.3e-25 84.8 12.3 4.4e-08 32.1 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KIK65377.1 - 4.1e-21 73.1 8.4 1.6e-06 27.5 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KIK65377.1 - 1.4e-12 47.3 9.9 0.00029 20.6 0.8 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KIK65377.1 - 4.8e-11 41.6 12.0 0.00077 18.8 0.4 4.2 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 KIK65377.1 - 2.9e-07 30.4 6.1 0.03 14.3 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIK65377.1 - 0.00017 21.8 3.8 0.19 12.1 0.6 3.6 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KIK65377.1 - 0.00018 21.8 2.8 0.12 12.7 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain Pan3_PK PF18101.1 KIK65377.1 - 0.041 13.9 0.2 0.073 13.0 0.2 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain EF-hand_2 PF09068.11 KIK65377.1 - 0.045 13.9 0.1 5.4 7.2 0.0 2.9 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 KIK65377.1 - 0.18 11.8 4.8 8.6 6.3 0.0 3.2 3 1 1 4 4 4 0 Caleosin related protein p25-alpha PF05517.12 KIK65377.1 - 0.57 10.3 3.5 17 5.6 0.1 2.8 1 1 2 3 3 3 0 p25-alpha EMC3_TMCO1 PF01956.16 KIK65378.1 - 3.7e-51 173.2 0.1 5e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like V-SNARE PF05008.15 KIK65379.1 - 7.1e-24 84.0 4.7 7.1e-24 84.0 4.7 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIK65379.1 - 7.4e-15 55.0 10.6 1.1e-14 54.4 5.6 2.7 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIK65379.1 - 0.00024 21.0 2.1 0.00028 20.8 0.5 1.9 2 0 0 2 2 2 1 Sec20 Prominin PF05478.11 KIK65379.1 - 0.013 13.5 2.8 0.28 9.1 0.2 2.1 2 0 0 2 2 2 0 Prominin LMBR1 PF04791.16 KIK65379.1 - 0.015 14.3 0.3 0.018 14.0 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 KIK65379.1 - 0.072 12.6 9.4 0.4 10.2 9.4 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Sec8_exocyst PF04048.14 KIK65379.1 - 0.094 12.6 5.3 3.8 7.4 0.0 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2564 PF10819.8 KIK65379.1 - 0.13 12.7 8.1 0.77 10.2 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2564) Laminin_I PF06008.14 KIK65379.1 - 0.18 11.5 10.0 0.27 10.9 1.0 2.3 2 1 0 2 2 2 0 Laminin Domain I APG6_N PF17675.1 KIK65379.1 - 0.3 11.6 11.1 0.06 13.9 2.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 KIK65379.1 - 0.35 10.2 10.5 0.61 9.4 10.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 KIK65379.1 - 0.45 11.1 5.9 3.6 8.2 1.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 KIK65379.1 - 0.49 9.6 4.4 0.92 8.7 1.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 KIK65379.1 - 2.2 8.5 6.8 3.1 8.0 1.8 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KCH PF16944.5 KIK65380.1 - 2.1e-90 302.9 14.5 2.5e-90 302.7 14.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3917 PF13055.6 KIK65380.1 - 0.015 15.7 0.7 0.015 15.7 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3917) AGOG PF09171.10 KIK65380.1 - 0.046 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase TRAP-gamma PF07074.12 KIK65380.1 - 0.094 12.3 0.0 0.094 12.3 0.0 2.1 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) MMR_HSR1_Xtn PF16897.5 KIK65381.1 - 6.6e-40 135.4 0.7 3.2e-39 133.2 0.5 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KIK65381.1 - 5.7e-23 80.7 0.0 1e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KIK65381.1 - 3.4e-20 72.2 0.0 6.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK65381.1 - 3.7e-08 33.0 0.2 9.4e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KIK65381.1 - 0.013 14.5 0.6 0.026 13.5 0.2 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KIK65381.1 - 0.028 14.5 0.6 11 6.0 0.4 2.6 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KIK65381.1 - 0.28 11.1 1.1 1.5 8.7 0.2 2.4 2 1 0 2 2 2 0 RsgA GTPase Ribonuc_red_sm PF00268.21 KIK65382.1 - 3.7e-118 394.0 0.7 4.6e-118 393.7 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Peptidase_S24 PF00717.23 KIK65383.1 - 1.8e-11 43.8 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIK65383.1 - 0.00093 19.0 0.0 1.1 9.1 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Sugar_tr PF00083.24 KIK65384.1 - 4.8e-110 368.5 21.8 5.7e-110 368.3 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK65384.1 - 5.8e-24 84.7 37.6 1e-17 64.2 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Holin_2-3 PF13272.6 KIK65384.1 - 0.034 14.4 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin OATP PF03137.20 KIK65384.1 - 4.2 5.6 15.1 0.022 13.1 1.8 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sec63 PF02889.16 KIK65385.1 - 5.1e-78 261.8 0.0 7.8e-78 261.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIK65385.1 - 4e-33 114.7 0.8 1.5e-26 93.2 0.3 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KIK65385.1 - 9e-18 64.8 0.0 7.1e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK65385.1 - 6.8e-07 29.6 0.1 1.6e-05 25.2 0.0 3.2 3 1 0 3 3 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK65385.1 - 8.2e-07 29.4 0.3 0.013 15.8 0.2 3.4 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK65385.1 - 6e-06 26.1 0.5 0.1 12.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK65385.1 - 2.1e-05 24.9 0.2 0.089 13.1 0.2 2.6 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 KIK65385.1 - 0.00031 20.7 0.1 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 Helicase UvrD-helicase PF00580.21 KIK65385.1 - 0.023 14.2 0.1 2.4 7.6 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 KIK65385.1 - 0.025 14.1 0.0 6.7 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KIK65385.1 - 0.07 12.9 0.1 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 KIK65386.1 - 9.4e-64 215.8 0.0 1.1e-63 215.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIK65386.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIK65386.1 - 0.00028 19.5 0.0 0.00044 18.9 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KIK65386.1 - 0.00051 19.4 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIK65386.1 - 0.0039 16.2 0.0 0.046 12.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Gyro_capsid PF04162.12 KIK65386.1 - 0.063 11.8 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) ECF_trnsprt PF12822.7 KIK65387.1 - 0.23 11.6 12.5 0.48 10.5 11.8 1.9 1 1 0 1 1 1 0 ECF transporter, substrate-specific component FYVE PF01363.21 KIK65388.1 - 4.4e-20 71.6 7.3 4.4e-20 71.6 7.3 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KIK65388.1 - 2.2e-08 34.3 20.9 5.8e-08 33.0 3.7 4.0 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 KIK65388.1 - 7.2e-06 25.8 3.1 7.2e-06 25.8 3.1 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK65388.1 - 5.6e-05 23.4 4.2 0.00035 20.8 2.2 3.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIK65388.1 - 0.0052 16.5 5.3 0.0052 16.5 5.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KIK65388.1 - 0.073 13.1 22.5 0.57 10.2 3.7 4.1 4 0 0 4 4 4 0 zinc-RING finger domain TackOD1 PF18551.1 KIK65388.1 - 0.51 10.0 11.7 3.4 7.3 0.1 2.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 zf-C3HC4_3 PF13920.6 KIK65388.1 - 2.1 8.2 21.6 0.9 9.5 2.9 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 KIK65388.1 - 5.8 7.6 6.2 11 6.7 0.0 3.3 3 0 0 3 3 3 0 Trm112p-like protein zf-AN1 PF01428.16 KIK65388.1 - 6.5 7.0 14.9 7.8 6.8 11.5 2.9 2 1 1 3 3 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KIK65388.1 - 8.6 6.6 18.5 1.2 9.3 0.1 4.2 3 1 0 3 3 3 0 Zinc ribbon domain DUF2018 PF09442.10 KIK65389.1 - 0.099 13.6 1.1 1.3 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF720 PF05302.11 KIK65389.1 - 0.7 9.7 2.9 1.4 8.8 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) PI31_Prot_N PF11566.8 KIK65390.1 - 4.1e-45 153.5 0.1 5.5e-45 153.1 0.1 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KIK65390.1 - 5e-10 40.4 26.1 9.7e-09 36.3 26.1 2.6 1 1 0 1 1 1 1 PI31 proteasome regulator Nsp1_C PF05064.13 KIK65391.1 - 3.9e-32 110.5 1.2 2.9e-31 107.7 0.3 2.1 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KIK65391.1 - 1.2e-05 26.0 27.4 1.2e-05 26.0 27.4 4.8 1 1 1 2 2 1 1 Nucleoporin FG repeat region FlaC_arch PF05377.11 KIK65391.1 - 0.019 15.3 7.4 0.4 11.1 0.4 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.6 KIK65391.1 - 0.1 12.8 6.7 2.4 8.3 6.7 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.12 KIK65391.1 - 0.11 12.5 3.4 0.34 10.9 0.1 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5102 PF17104.5 KIK65391.1 - 0.19 11.7 1.7 16 5.4 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) RapH_N PF18801.1 KIK65391.1 - 0.23 11.5 0.5 0.53 10.4 0.5 1.5 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal EzrA PF06160.12 KIK65391.1 - 0.33 9.1 3.3 3.6 5.7 3.3 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 KIK65391.1 - 0.36 11.4 4.3 3.1 8.4 1.0 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF5446 PF17522.2 KIK65391.1 - 0.38 11.0 3.3 9.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5446) NPV_P10 PF05531.12 KIK65391.1 - 0.42 11.1 5.2 75 3.9 0.0 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 KIK65391.1 - 0.62 10.1 4.4 0.75 9.9 1.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 KIK65391.1 - 0.95 9.8 6.4 4.7 7.6 0.1 3.0 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FPP PF05911.11 KIK65391.1 - 0.95 7.6 4.8 10 4.2 0.0 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KIK65391.1 - 1.2 8.0 5.0 3.8 6.3 2.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Cytochrom_B561 PF03188.16 KIK65392.1 - 0.029 14.5 3.7 0.4 10.8 0.5 2.6 1 1 0 2 2 2 0 Eukaryotic cytochrome b561 Phage_r1t_holin PF16945.5 KIK65392.1 - 0.056 13.6 0.5 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin DUF5345 PF17280.2 KIK65392.1 - 0.56 10.2 0.1 0.56 10.2 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Phage_holin_3_2 PF04550.12 KIK65392.1 - 1.1 9.9 3.2 0.45 11.1 0.3 1.8 2 0 0 2 2 2 0 Phage holin family 2 DUF2975 PF11188.8 KIK65392.1 - 2.6 8.0 8.0 6.3 6.7 8.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) AAA_16 PF13191.6 KIK65393.1 - 0.00016 22.1 0.5 0.084 13.2 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zot PF05707.12 KIK65393.1 - 0.00019 21.1 0.0 0.00083 19.0 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 KIK65393.1 - 0.0017 18.6 0.6 2.1 8.7 0.1 2.7 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 KIK65393.1 - 0.0027 17.9 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 KIK65393.1 - 0.0029 18.0 0.0 0.052 14.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIK65393.1 - 0.056 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Hint PF01079.20 KIK65393.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Hint module FtsK_SpoIIIE PF01580.18 KIK65393.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.7 KIK65393.1 - 0.16 10.9 0.0 13 4.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.9 KIK65393.1 - 0.17 11.1 0.1 0.84 8.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Methyltransf_8 PF05148.15 KIK65394.1 - 1.7e-63 214.4 0.0 3.5e-63 213.4 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KIK65394.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK65394.1 - 0.00014 22.5 0.0 0.00052 20.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK65394.1 - 0.00047 20.8 0.0 0.0025 18.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK65394.1 - 0.0037 18.0 0.2 0.14 12.9 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 KIK65394.1 - 0.058 11.9 0.3 0.27 9.8 0.0 2.1 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPRTase PF14681.6 KIK65395.1 - 4.1e-66 222.4 0.0 4.7e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FAD_binding_1 PF00667.20 KIK65396.1 - 1.3e-52 178.6 0.0 1.8e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KIK65396.1 - 4.2e-07 30.6 0.0 9.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KIK65396.1 - 4.2e-07 30.2 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase POR_N PF01855.19 KIK65396.1 - 7.8e-05 22.5 0.2 0.00015 21.6 0.2 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_6 PF00970.24 KIK65396.1 - 0.054 13.9 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.19 KIK65397.1 - 9.6e-107 357.9 7.5 1.2e-106 357.7 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GFO_IDH_MocA PF01408.22 KIK65398.1 - 1.9e-21 77.1 0.0 3.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK65398.1 - 1.8e-09 37.6 0.0 3.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pkinase PF00069.25 KIK65399.1 - 6e-63 212.7 0.0 7.4e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65399.1 - 1.6e-29 103.0 0.0 2.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK65399.1 - 0.002 17.1 0.0 0.0048 15.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK65399.1 - 0.0079 15.5 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK65399.1 - 0.035 14.0 0.0 0.16 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DEAD PF00270.29 KIK65401.1 - 4.5e-52 176.4 0.0 3.8e-51 173.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK65401.1 - 5.5e-26 91.1 0.0 2.1e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK65401.1 - 0.00026 21.1 0.0 0.00096 19.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NuDC PF16273.5 KIK65401.1 - 0.0044 17.5 0.1 0.0044 17.5 0.1 6.6 6 2 2 8 8 8 1 Nuclear distribution C domain CsbD PF05532.12 KIK65402.1 - 0.013 15.4 2.8 0.028 14.3 2.8 1.6 1 0 0 1 1 1 0 CsbD-like ubiquitin PF00240.23 KIK65403.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family cNMP_binding PF00027.29 KIK65404.1 - 2.5e-28 98.0 4.2 4.5e-11 42.7 0.5 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain RIIa PF02197.17 KIK65404.1 - 2.8e-11 42.9 0.1 5.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Apt1 PF10351.9 KIK65406.1 - 0.018 14.0 9.3 0.02 13.8 9.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 KIK65406.1 - 5.8 4.9 7.9 7.9 4.5 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KAR9 PF08580.10 KIK65406.1 - 7 5.1 18.0 11 4.4 18.0 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MFS_1 PF07690.16 KIK65407.1 - 1.5e-26 93.2 15.8 2e-25 89.5 17.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PRCH PF03967.13 KIK65407.1 - 0.072 13.3 0.0 4.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region RCR PF12273.8 KIK65407.1 - 0.089 13.4 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ytp1 PF10355.9 KIK65408.1 - 1.1e-106 356.1 6.6 1.7e-106 355.5 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIK65408.1 - 2.2e-11 43.5 4.1 2.2e-11 43.5 4.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SK_channel PF03530.14 KIK65408.1 - 0.0093 15.9 0.1 0.098 12.6 0.1 2.3 2 0 0 2 2 2 1 Calcium-activated SK potassium channel zf-CCCH PF00642.24 KIK65409.1 - 0.0023 17.8 2.0 0.0023 17.8 2.0 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK65410.1 - 0.00096 18.9 1.4 0.00096 18.9 1.4 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIK65410.1 - 0.0021 17.9 2.0 0.0021 17.9 2.0 3.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KIK65410.1 - 0.46 10.7 13.4 0.51 10.6 1.7 2.5 2 0 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KIK65410.1 - 1.7 9.4 13.6 1.8 9.3 1.5 2.9 1 1 1 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 KIK65410.1 - 6 7.1 21.2 0.055 13.6 3.8 3.5 3 0 0 3 3 3 0 Zinc finger domain CDT1_C PF16679.5 KIK65411.1 - 1.6e-15 57.3 0.3 1.3e-14 54.4 0.0 2.6 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Abhydrolase_6 PF12697.7 KIK65412.1 - 2.3e-09 38.2 4.7 2.3e-09 38.2 4.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK65412.1 - 0.00012 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK65412.1 - 0.028 14.1 1.6 0.032 13.9 0.3 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK65413.1 - 1.8e-10 41.8 0.2 2.3e-10 41.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK65413.1 - 4.4e-06 26.1 0.0 1.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK65413.1 - 0.014 15.1 0.2 0.039 13.6 0.2 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.22 KIK65414.1 - 3.9e-19 69.6 0.8 6.5e-19 68.9 0.8 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK65414.1 - 3e-07 30.5 0.0 1.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain TrkA_N PF02254.18 KIK65414.1 - 0.004 17.4 0.3 0.0073 16.5 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 KIK65414.1 - 0.056 13.0 0.3 0.16 11.5 0.2 1.7 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GARS_N PF02844.15 KIK65414.1 - 0.059 14.1 0.1 0.23 12.3 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain F420_oxidored PF03807.17 KIK65414.1 - 0.14 12.8 0.6 0.36 11.5 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Proteasome PF00227.26 KIK65416.1 - 1.1e-41 142.5 0.3 1.2e-41 142.3 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit CSN8_PSD8_EIF3K PF10075.9 KIK65417.1 - 2.7e-30 105.3 0.1 3.6e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KIK65417.1 - 1.9e-06 27.5 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 KIK65418.1 - 9.8e-48 162.2 0.0 1.2e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK65418.1 - 1.9e-13 49.8 0.1 3.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nup88 PF10168.9 KIK65419.1 - 6.3e-21 73.9 4.4 4e-12 44.8 0.0 3.2 3 1 0 3 3 3 2 Nuclear pore component Bap31_Bap29_C PF18035.1 KIK65419.1 - 0.081 12.9 1.4 0.2 11.7 1.4 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Nup54 PF13874.6 KIK65419.1 - 0.35 11.0 7.6 0.76 9.9 7.1 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 MFS_1 PF07690.16 KIK65420.1 - 1.1e-37 129.8 25.5 1.1e-37 129.8 25.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KIK65421.1 - 2e-86 290.2 0.2 2.3e-86 290.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Aldo_ket_red PF00248.21 KIK65423.1 - 5.2e-40 137.5 0.0 5.9e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rep_fac_C PF08542.11 KIK65424.1 - 0.095 13.1 0.1 0.4 11.1 0.1 2.0 2 1 0 2 2 2 0 Replication factor C C-terminal domain Mg_trans_NIPA PF05653.14 KIK65425.1 - 5.3e-62 209.6 11.6 1.5e-57 195.0 9.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIK65425.1 - 1.9e-05 24.9 1.5 1.9e-05 24.9 1.5 3.9 3 1 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KIK65425.1 - 0.0014 18.2 6.4 0.0028 17.2 6.4 1.5 1 0 0 1 1 1 1 Solute carrier family 35 WD40 PF00400.32 KIK65426.1 - 3.8e-07 30.7 0.1 0.001 19.9 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65426.1 - 0.00051 20.3 0.0 1.5 9.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID-31kDa PF02291.15 KIK65427.1 - 1.6e-33 115.4 0.0 2.2e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KIK65427.1 - 8.5e-06 25.9 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KIK65427.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.6 KIK65427.1 - 0.0028 18.0 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein NifU_N PF01592.16 KIK65428.1 - 9.9e-55 184.2 0.1 4e-53 179.0 0.0 2.0 1 1 1 2 2 2 2 NifU-like N terminal domain F-box-like PF12937.7 KIK65429.1 - 9e-06 25.5 5.9 2.3e-05 24.2 5.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK65429.1 - 5.6 7.5 12.3 21 5.7 0.0 5.5 3 1 5 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK65429.1 - 6.1 6.7 8.5 5.7 6.8 0.2 4.5 4 1 0 4 4 4 0 Leucine rich repeat Pkinase PF00069.25 KIK65430.1 - 5.1e-73 245.7 0.0 7e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65430.1 - 4.3e-36 124.5 0.0 6.6e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65430.1 - 0.0003 20.2 1.0 2 7.7 0.1 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KIK65430.1 - 0.0043 17.0 0.0 0.48 10.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK65430.1 - 0.024 13.4 0.1 0.042 12.6 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 KIK65430.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Tctex-1 PF03645.13 KIK65433.1 - 1.6e-12 47.6 0.0 1.8e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family PEX11 PF05648.14 KIK65434.1 - 3.8e-14 52.7 2.7 5.4e-13 48.9 2.7 2.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2076 PF09849.9 KIK65435.1 - 0.014 15.5 0.4 0.02 14.9 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SNARE_assoc PF09335.11 KIK65436.1 - 1.4e-14 54.6 5.3 1.4e-14 54.6 5.3 2.1 2 1 1 3 3 3 1 SNARE associated Golgi protein CoA_binding_3 PF13727.6 KIK65436.1 - 0.025 14.6 2.5 1 9.4 2.0 2.6 2 1 0 2 2 2 0 CoA-binding domain LEDGF PF11467.8 KIK65438.1 - 0.048 13.3 0.4 0.069 12.8 0.4 1.2 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) DUF948 PF06103.11 KIK65438.1 - 0.076 13.3 0.0 2.8 8.3 0.2 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cnd1 PF12717.7 KIK65438.1 - 0.095 12.7 0.8 0.17 11.9 0.7 1.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PAH PF02671.21 KIK65438.1 - 0.13 12.4 0.2 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat UME PF08064.13 KIK65438.1 - 0.2 11.6 0.0 0.68 9.9 0.0 1.8 2 0 0 2 2 2 0 UME (NUC010) domain FUSC PF04632.12 KIK65438.1 - 0.26 9.8 0.0 0.31 9.5 0.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FTCD_C PF04961.12 KIK65438.1 - 0.52 10.0 5.3 0.49 10.1 2.0 2.0 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase CinA_KH PF18146.1 KIK65438.1 - 0.64 10.2 2.7 1.4 9.1 0.3 2.5 1 1 2 3 3 3 0 Damage-inducible protein CinA KH domain V_ATPase_I PF01496.19 KIK65438.1 - 0.76 7.6 3.4 0.95 7.3 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sigma70_r3 PF04539.16 KIK65440.1 - 0.0009 19.3 0.7 0.0009 19.3 0.7 1.7 2 0 0 2 2 2 1 Sigma-70 region 3 DUF4953 PF16313.5 KIK65440.1 - 0.0082 15.4 0.2 0.0085 15.3 0.2 1.0 1 0 0 1 1 1 1 Met-zincin DUF948 PF06103.11 KIK65440.1 - 0.077 13.3 0.8 1.6 9.1 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1394 PF07159.12 KIK65440.1 - 0.12 11.6 0.6 0.13 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Miga PF10265.9 KIK65440.1 - 0.14 11.1 0.7 0.16 10.9 0.7 1.0 1 0 0 1 1 1 0 Mitoguardin Mlp PF03304.13 KIK65440.1 - 0.27 11.4 5.5 2.8 8.1 2.1 2.1 1 1 0 2 2 2 0 Mlp lipoprotein family Ku_C PF03730.14 KIK65440.1 - 0.68 10.7 7.0 4.8 7.9 6.1 2.0 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm V_ATPase_I PF01496.19 KIK65440.1 - 1.1 7.1 4.3 1.2 6.9 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.20 KIK65440.1 - 1.3 7.1 5.7 1.4 7.0 5.7 1.1 1 0 0 1 1 1 0 Hsp70 protein HSF_DNA-bind PF00447.17 KIK65441.1 - 9.9e-19 67.8 0.0 1.8e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KIK65441.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Ets-domain Pkinase PF00069.25 KIK65442.1 - 1.5e-70 237.6 0.0 2e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65442.1 - 4.7e-28 98.2 0.3 1.1e-25 90.4 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65442.1 - 5.6e-09 35.7 0.8 0.00011 21.6 0.1 2.9 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIK65442.1 - 0.00016 20.6 0.3 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KIK65442.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK65442.1 - 0.17 11.8 0.0 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KIK65443.1 - 6.3e-35 120.7 35.2 2.7e-33 115.4 35.2 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK65443.1 - 0.00038 19.0 6.9 0.0052 15.3 6.8 2.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COA2 PF17051.5 KIK65444.1 - 3.3e-06 27.1 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Ribosomal_S14 PF00253.21 KIK65445.1 - 8.9e-21 73.4 0.7 1.4e-20 72.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.8 KIK65446.1 - 2.8e-13 49.9 1.0 1.8e-12 47.3 0.5 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KIK65446.1 - 1.2e-09 38.1 5.3 2.7e-09 37.0 5.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK65446.1 - 0.0022 18.1 9.6 0.0041 17.2 3.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper DUF5101 PF17031.5 KIK65446.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) bZIP_Maf PF03131.17 KIK65446.1 - 1.3 9.6 7.0 3.3 8.3 3.6 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor RRM_1 PF00076.22 KIK65449.1 - 3.5e-27 94.0 0.0 1.7e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 KIK65449.1 - 1.6e-23 82.2 1.8 3.3e-23 81.2 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KIK65449.1 - 2.1e-05 24.3 2.8 0.00084 19.2 1.5 2.5 2 0 0 2 2 2 1 G-patch domain DbpA PF03880.15 KIK65449.1 - 0.012 15.5 0.0 7.4 6.6 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_5 PF13893.6 KIK65449.1 - 0.024 14.2 0.0 10 5.8 0.0 3.0 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KIK65449.1 - 0.51 10.1 1.7 31 4.3 0.4 3.1 2 1 0 2 2 2 0 Ribonuclease B OB domain Glyco_hydro_cc PF11790.8 KIK65450.1 - 1.5e-66 224.4 8.1 1.9e-66 224.0 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core G6PD_bact PF10786.9 KIK65450.1 - 0.085 12.4 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Macoilin PF09726.9 KIK65450.1 - 1.7 7.1 13.6 2.2 6.7 13.6 1.1 1 0 0 1 1 1 0 Macoilin family MyTH4 PF00784.17 KIK65451.1 - 0.13 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 MyTH4 domain Ribosomal_L11 PF00298.19 KIK65453.1 - 3.9e-29 101.0 0.3 6e-29 100.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KIK65453.1 - 1.5e-26 92.0 0.9 2.3e-26 91.4 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.17 KIK65454.1 - 5.3e-28 98.1 0.1 7.3e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK65454.1 - 4.8e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DEP PF00610.21 KIK65454.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) adh_short PF00106.25 KIK65455.1 - 3.2e-11 43.1 0.0 8.1e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK65455.1 - 2.2e-08 34.0 0.0 3.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK65455.1 - 4.6e-07 29.9 0.0 6.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK65455.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 KIK65455.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) C2 PF00168.30 KIK65457.1 - 1.2e-12 48.0 0.0 1.6e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain Tau95 PF09734.9 KIK65458.1 - 3.2e-39 134.9 1.7 4.1e-39 134.6 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KIK65458.1 - 1.3e-30 106.2 0.0 3.1e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain Fibritin_C PF07921.12 KIK65459.1 - 0.082 13.0 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 Fibritin C-terminal region Ribosomal_L29e PF01779.17 KIK65460.1 - 2.4e-19 69.3 9.7 3.1e-19 69.0 9.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Aconitase PF00330.20 KIK65461.1 - 9.7e-163 542.4 0.0 1.2e-162 542.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK65461.1 - 3.4e-39 134.2 0.0 5.7e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_hydro_125 PF06824.11 KIK65463.1 - 4.3e-153 510.1 0.2 5e-153 509.9 0.2 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Pkr1 PF08636.10 KIK65465.1 - 1.4e-18 66.8 5.7 1.8e-18 66.4 5.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 BPD_transp_1 PF00528.22 KIK65467.1 - 0.016 14.9 0.3 0.017 14.9 0.3 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF1129 PF06570.11 KIK65468.1 - 0.72 9.3 5.8 0.86 9.1 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) LSM PF01423.22 KIK65469.1 - 3.9e-20 71.3 0.0 4.3e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK65469.1 - 0.072 13.2 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 KIK65469.1 - 0.097 12.3 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Cas_NE0113 PF09623.10 KIK65469.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) MDM10 PF12519.8 KIK65471.1 - 2.1e-95 320.3 0.0 5.2e-84 282.8 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KIK65471.1 - 0.018 14.5 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic porin PPR_2 PF13041.6 KIK65472.1 - 2.8e-05 24.2 0.4 0.25 11.6 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_1 PF12854.7 KIK65472.1 - 0.024 14.3 0.2 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Rdx PF10262.9 KIK65473.1 - 1.5e-24 86.0 0.0 2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family AAA PF00004.29 KIK65474.1 - 8.1e-32 110.4 0.0 1.4e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK65474.1 - 5e-08 33.5 0.2 1.9e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK65474.1 - 3.8e-07 30.5 0.1 3.1e-06 27.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK65474.1 - 8.2e-06 26.4 0.0 1.8e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK65474.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIK65474.1 - 0.00015 21.9 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KIK65474.1 - 0.00028 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIK65474.1 - 0.00037 19.7 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KIK65474.1 - 0.00045 20.4 0.0 0.00098 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK65474.1 - 0.00071 19.4 0.1 0.0022 17.8 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KIK65474.1 - 0.00098 18.9 0.0 0.002 17.9 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase AAA_30 PF13604.6 KIK65474.1 - 0.0016 18.2 0.0 0.0064 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK65474.1 - 0.0017 18.2 0.1 0.0044 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK65474.1 - 0.002 18.2 0.2 0.0069 16.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK65474.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIK65474.1 - 0.0022 17.9 0.2 0.0075 16.2 0.2 1.9 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KIK65474.1 - 0.0024 17.5 0.3 0.33 10.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 KIK65474.1 - 0.0026 18.0 0.0 0.0071 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK65474.1 - 0.0036 17.0 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KIK65474.1 - 0.0038 17.2 0.1 2.7 7.8 0.1 2.2 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK65474.1 - 0.0045 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KIK65474.1 - 0.0063 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KIK65474.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.14 KIK65474.1 - 0.013 14.8 0.0 1.2 8.2 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 KIK65474.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KIK65474.1 - 0.023 15.0 0.2 0.22 11.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIK65474.1 - 0.032 14.1 0.0 0.089 12.7 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KIK65474.1 - 0.046 14.1 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK65474.1 - 0.053 14.0 0.0 0.098 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SKI PF01202.22 KIK65474.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.21 KIK65474.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KIK65474.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 KIK65474.1 - 0.082 12.1 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 KIK65474.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin2 PF13189.6 KIK65474.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family PhoH PF02562.16 KIK65474.1 - 0.15 11.5 0.0 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.9 KIK65474.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 KIK65474.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2423 PF10338.9 KIK65475.1 - 2.3e-15 56.6 5.8 3e-15 56.2 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 KIK65475.1 - 0.079 13.5 0.4 0.098 13.2 0.4 1.2 1 0 0 1 1 1 0 Learning-associated protein BOP1NT PF08145.12 KIK65479.1 - 2.3e-104 348.9 7.2 2.3e-104 348.9 7.2 1.8 2 1 1 3 3 3 1 BOP1NT (NUC169) domain WD40 PF00400.32 KIK65479.1 - 5.9e-19 68.1 10.6 0.0003 21.5 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65479.1 - 3.7e-07 30.3 0.5 1 9.7 0.1 5.1 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3727 PF12527.8 KIK65479.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3727) GCIP PF13324.6 KIK65479.1 - 8.8 5.8 6.1 15 5.1 6.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Actin PF00022.19 KIK65480.1 - 2.4e-111 372.2 0.0 2.7e-111 372.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIK65480.1 - 7.8e-08 31.5 0.0 0.0087 14.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Ncstrn_small PF18266.1 KIK65480.1 - 0.21 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin small lobe Sedlin_N PF04628.13 KIK65482.1 - 9e-36 122.9 0.0 1.3e-34 119.1 0.0 2.0 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KIK65482.1 - 1.6e-08 34.6 0.0 4.6e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Sybindin-like family Rhomboid PF01694.22 KIK65483.1 - 5.2e-26 91.4 10.1 8.5e-26 90.8 10.1 1.3 1 0 0 1 1 1 1 Rhomboid family CLASP_N PF12348.8 KIK65484.1 - 9.5e-71 238.0 1.2 1.7e-61 207.7 0.0 4.3 5 0 0 5 5 5 3 CLASP N terminal HEAT PF02985.22 KIK65484.1 - 4.3e-06 26.5 0.2 1.4 9.4 0.1 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KIK65484.1 - 0.00015 21.8 0.0 0.65 10.0 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK65484.1 - 0.0098 16.4 1.6 3.5 8.2 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat SIR2 PF02146.17 KIK65485.1 - 1.4e-18 67.5 0.0 1.9e-16 60.5 0.0 2.7 1 1 0 1 1 1 1 Sir2 family zf-ribbon_3 PF13248.6 KIK65485.1 - 0.022 14.2 2.9 0.66 9.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KIK65485.1 - 6.9 6.5 7.7 18 5.2 1.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain LSM PF01423.22 KIK65486.1 - 1.6e-21 75.8 0.0 1.7e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK65486.1 - 0.0028 17.8 0.0 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 KIK65487.1 - 1.2e-18 67.1 0.9 2.3e-18 66.2 0.9 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK65487.1 - 0.015 15.7 0.6 0.044 14.1 0.0 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 ICAT PF06384.11 KIK65487.1 - 0.031 14.5 1.0 0.06 13.6 1.0 1.5 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT PfkB PF00294.24 KIK65488.1 - 3.4e-15 56.1 0.0 5.7e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIK65488.1 - 0.0087 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ACPS PF01648.20 KIK65489.1 - 5.3e-13 49.1 0.0 1.5e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily RNA_pol_Rpc34 PF05158.12 KIK65490.1 - 5.7e-72 242.9 0.5 3.4e-69 233.8 0.5 2.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.14 KIK65490.1 - 0.016 15.2 0.1 0.083 12.9 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family MarR PF01047.22 KIK65490.1 - 0.021 14.7 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 MarR family HxlR PF01638.17 KIK65490.1 - 0.041 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Hamartin PF04388.12 KIK65490.1 - 0.047 12.4 14.5 0.055 12.1 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein PAP1 PF08601.10 KIK65490.1 - 0.12 12.0 23.0 0.22 11.2 23.0 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RPA_C PF08784.11 KIK65490.1 - 0.41 11.3 0.1 0.41 11.3 0.1 3.0 3 1 0 3 3 3 0 Replication protein A C terminal GREB1 PF15782.5 KIK65490.1 - 1.8 5.6 20.8 2.2 5.3 20.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KIK65490.1 - 2.7 6.4 25.3 3.9 5.9 25.3 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KIK65490.1 - 4.1 5.4 22.3 6 4.9 22.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 KIK65490.1 - 5.7 5.9 24.2 9.1 5.2 24.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) F-box-like PF12937.7 KIK65491.1 - 0.004 17.0 0.1 0.0078 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like tRNA-synt_2 PF00152.20 KIK65492.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) IMD PF08397.11 KIK65494.1 - 0.00019 20.9 2.5 0.00032 20.1 2.5 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR_3 PF16746.5 KIK65494.1 - 0.00054 19.7 3.0 0.0009 19.0 3.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family OmpH PF03938.14 KIK65494.1 - 0.024 15.0 4.0 0.049 14.0 4.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KIK65494.1 - 0.024 13.5 3.9 0.043 12.7 3.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SKA2 PF16740.5 KIK65494.1 - 0.49 10.2 8.5 0.15 11.8 3.5 2.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DotA PF11388.8 KIK65494.1 - 0.58 10.4 8.8 0.053 13.7 3.1 2.2 2 0 0 2 2 2 0 Phagosome trafficking protein DotA RRM_1 PF00076.22 KIK65495.1 - 3e-18 65.4 0.0 4.7e-17 61.6 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 KIK65495.1 - 1.4e-15 57.2 0.1 2.5e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Fungal_trans PF04082.18 KIK65496.1 - 7.7e-34 116.9 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK65496.1 - 6.2e-08 32.6 14.7 1.1e-07 31.8 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KIK65497.1 - 4.3e-29 101.7 0.5 6.8e-29 101.0 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK65497.1 - 1.2e-19 70.3 0.0 5.1e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK65497.1 - 7.6e-12 45.7 1.3 1.4e-11 44.8 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIK65497.1 - 2.2e-11 44.4 0.0 4.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain MRP-S26 PF14943.6 KIK65498.1 - 0.022 14.7 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 SIR2 PF02146.17 KIK65499.1 - 1.5e-36 126.0 0.0 3.1e-35 121.7 0.0 2.6 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KIK65499.1 - 0.0033 16.4 0.5 0.11 11.4 0.0 2.0 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KIK65499.1 - 0.0072 16.1 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Suc_Fer-like PF06999.12 KIK65500.1 - 1.8e-48 165.0 0.0 2.6e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF1935 PF09149.10 KIK65501.1 - 0.16 12.3 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) C2 PF00168.30 KIK65502.1 - 1.1e-09 38.5 0.1 3.4e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain Pkinase PF00069.25 KIK65504.1 - 7.1e-67 225.5 0.0 9.5e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65504.1 - 1e-29 103.6 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIK65504.1 - 1e-17 64.5 0.1 6.4e-17 62.0 0.1 2.4 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KIK65504.1 - 3.8e-08 33.0 0.1 8.3e-07 28.6 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIK65504.1 - 1.2e-06 27.7 0.1 2.1e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KIK65504.1 - 0.0012 18.6 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK65504.1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK65504.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIK65504.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP1_TM PF14812.6 KIK65504.1 - 8.9 6.8 6.8 2 8.8 2.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Diphthamide_syn PF01866.17 KIK65505.1 - 3.8e-87 292.5 0.0 1.6e-50 172.3 0.0 3.1 2 1 0 2 2 2 2 Putative diphthamide synthesis protein PCP_red PF08369.10 KIK65505.1 - 0.031 14.5 0.2 0.062 13.5 0.2 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit RRM_1 PF00076.22 KIK65506.1 - 1.9e-11 43.6 0.0 2.2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK65506.1 - 5.1e-06 26.1 0.0 6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPC1_N PF16414.5 KIK65508.1 - 8.6e-68 228.5 4.6 1.4e-67 227.8 4.6 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KIK65508.1 - 2.9e-45 154.7 0.2 6.5e-15 54.3 0.0 3.9 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KIK65508.1 - 9.1e-34 116.5 2.3 1.2e-16 60.9 0.0 2.8 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KIK65508.1 - 2.1e-05 24.5 0.8 4.2e-05 23.5 0.8 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 KIK65508.1 - 0.0054 14.5 5.8 0.0084 13.8 5.8 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Tyrosinase PF00264.20 KIK65510.1 - 8.7e-32 111.2 11.5 1.6e-29 103.8 11.5 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase Ribosomal_S11 PF00411.19 KIK65511.1 - 2.7e-14 53.5 0.5 1.6e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.12 KIK65512.1 - 2.1e-26 91.6 5.9 2.3e-26 91.5 5.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Bmt2 PF11968.8 KIK65513.1 - 4.7e-64 216.2 0.0 6.3e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KIK65513.1 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2373 PF10180.9 KIK65514.1 - 1.5e-19 69.6 0.2 2.2e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Arf PF00025.21 KIK65515.1 - 5.4e-71 237.6 0.0 6.4e-71 237.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK65515.1 - 5e-15 55.4 0.0 6.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KIK65515.1 - 5.4e-14 52.4 0.0 7.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIK65515.1 - 7.2e-14 51.7 0.1 5.6e-09 35.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KIK65515.1 - 1.7e-10 40.7 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIK65515.1 - 2.6e-09 36.8 0.0 3.3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK65515.1 - 0.00031 20.8 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 KIK65515.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) WD40 PF00400.32 KIK65516.1 - 1.4e-24 85.9 5.3 8.2e-06 26.5 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65516.1 - 1.1e-06 28.9 0.0 0.015 15.6 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 KIK65517.1 - 6.7e-41 138.3 12.6 2.7e-10 40.3 0.1 5.4 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK65517.1 - 7.8e-39 131.7 0.1 4.6e-12 46.0 0.0 5.3 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK65517.1 - 9.7e-06 25.9 13.5 0.99 9.8 0.0 5.2 5 0 0 5 5 5 3 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KIK65517.1 - 0.032 14.5 4.3 0.084 13.2 0.0 3.3 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4638 PF15472.6 KIK65517.1 - 0.095 12.4 2.7 0.22 11.3 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TMEM208_SND2 PF05620.11 KIK65518.1 - 2.2e-54 183.7 0.0 2.5e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Asp PF00026.23 KIK65519.1 - 2.3e-71 240.8 7.4 3.1e-71 240.4 7.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK65519.1 - 5.6e-06 26.7 3.9 0.0036 17.5 2.4 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK65519.1 - 0.011 16.4 8.0 1.7 9.3 0.7 3.5 3 1 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 KIK65519.1 - 0.012 15.4 0.1 0.054 13.3 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal HALZ PF02183.18 KIK65520.1 - 2.6 8.3 30.8 0.19 12.0 0.3 6.6 5 1 2 7 7 7 0 Homeobox associated leucine zipper 7tm_7 PF08395.12 KIK65523.1 - 0.065 12.4 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Iso_dh PF00180.20 KIK65524.1 - 8.2e-98 327.7 0.0 1e-97 327.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.25 KIK65525.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK65525.1 - 9.1e-09 35.2 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DNA_pol3_alpha PF07733.12 KIK65525.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain Abhydrolase_1 PF00561.20 KIK65526.1 - 2.7e-22 79.6 0.0 1.5e-21 77.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK65526.1 - 9.6e-17 62.3 0.1 5.2e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK65526.1 - 2.7e-14 53.0 0.0 4.6e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KIK65526.1 - 5e-06 26.3 0.0 1.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Esterase PF00756.20 KIK65526.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KIK65526.1 - 0.00025 19.9 0.0 0.00056 18.7 0.0 1.5 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.13 KIK65526.1 - 0.00098 19.0 0.0 0.17 11.7 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KIK65526.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 KIK65526.1 - 0.0089 16.0 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 KIK65526.1 - 0.015 14.6 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3530 PF12048.8 KIK65526.1 - 0.11 11.9 2.5 0.4 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) Acyl_transf_1 PF00698.21 KIK65527.1 - 0.13 11.8 0.5 0.26 10.7 0.4 1.5 2 0 0 2 2 2 0 Acyl transferase domain cwf21 PF08312.12 KIK65528.1 - 7.3e-16 58.0 9.9 7.3e-16 58.0 9.9 2.7 2 1 0 2 2 2 1 cwf21 domain Aminotran_3 PF00202.21 KIK65529.1 - 5.4e-96 321.7 0.0 7.6e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Serine_rich PF08824.10 KIK65529.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain Aminotran_1_2 PF00155.21 KIK65530.1 - 1.3e-73 248.3 0.0 1.7e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK65530.1 - 7.4e-06 24.7 0.2 0.00016 20.4 0.0 2.4 3 0 0 3 3 3 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIK65530.1 - 0.00028 19.9 0.0 0.00055 19.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 KIK65530.1 - 0.051 13.4 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Cyto_heme_lyase PF01265.17 KIK65530.1 - 0.16 11.5 0.8 0.29 10.7 0.8 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Flavokinase PF01687.17 KIK65531.1 - 2.1e-31 108.5 0.0 2.5e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase SQS_PSY PF00494.19 KIK65532.1 - 4.7e-48 164.0 0.0 5.3e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Sld5 PF05916.11 KIK65533.1 - 0.00077 19.9 0.1 0.0011 19.4 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein CorA PF01544.18 KIK65533.1 - 0.067 12.5 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein adh_short_C2 PF13561.6 KIK65535.1 - 8.6e-66 221.8 0.0 1e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK65535.1 - 3.2e-47 160.5 0.0 4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK65535.1 - 7.9e-07 29.2 0.1 1.4e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK65535.1 - 0.032 14.1 0.2 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF948 PF06103.11 KIK65537.1 - 0.002 18.3 4.2 1.2 9.4 5.6 3.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KIK65537.1 - 0.0081 16.7 8.9 0.016 15.8 8.9 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 KIK65537.1 - 0.028 13.3 6.1 0.036 12.9 6.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG6 PF06419.11 KIK65537.1 - 0.039 12.2 5.6 0.05 11.8 5.6 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4407 PF14362.6 KIK65537.1 - 0.052 12.9 5.0 0.074 12.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Flagellin_N PF00669.20 KIK65537.1 - 0.11 12.6 6.6 0.3 11.2 6.3 1.8 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region V_ATPase_I PF01496.19 KIK65537.1 - 0.14 10.0 2.5 0.16 9.9 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DHR10 PF18595.1 KIK65537.1 - 0.18 11.8 17.4 1.2 9.2 17.4 2.2 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain OmpH PF03938.14 KIK65537.1 - 0.53 10.6 11.2 0.29 11.5 6.9 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 KIK65537.1 - 0.66 10.7 8.0 1 10.1 2.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 KIK65537.1 - 0.68 10.0 5.2 1.2 9.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SfLAP PF11139.8 KIK65537.1 - 0.81 9.1 2.7 2.6 7.4 2.7 1.9 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Occludin_ELL PF07303.13 KIK65537.1 - 0.97 10.2 7.0 16 6.3 0.2 2.7 1 1 2 3 3 3 0 Occludin homology domain Noelin-1 PF12308.8 KIK65537.1 - 2.9 7.9 7.2 4.9 7.2 3.9 2.6 2 1 1 3 3 3 0 Neurogenesis glycoprotein LRR_8 PF13855.6 KIK65538.1 - 9e-09 35.0 5.4 2.3e-07 30.5 4.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KIK65538.1 - 0.00011 22.5 3.0 0.00011 22.5 3.0 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK65538.1 - 0.44 11.3 3.8 2.8 8.8 0.6 3.8 2 2 1 3 3 3 0 Leucine Rich Repeat GAS2 PF02187.17 KIK65539.1 - 2.9e-12 46.5 1.7 4.3e-12 45.9 0.1 2.1 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain HTH_11 PF08279.12 KIK65539.1 - 0.007 16.3 0.4 0.042 13.8 0.1 2.5 2 0 0 2 2 2 1 HTH domain NAD_binding_1 PF00175.21 KIK65540.1 - 8.1e-11 42.5 0.0 1.4e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK65540.1 - 2.3e-09 37.5 0.0 4.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK65540.1 - 0.00016 21.8 0.0 0.0023 18.1 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Amidohydro_2 PF04909.14 KIK65541.1 - 3.1e-07 30.5 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KIK65541.1 - 3.7e-07 29.8 0.0 5.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Kinesin PF00225.23 KIK65542.1 - 2.9e-108 361.8 0.0 6.1e-108 360.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK65542.1 - 1.3e-23 83.6 0.0 2.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding EMP24_GP25L PF01105.24 KIK65543.1 - 3.9e-50 170.3 0.0 4.5e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 KIK65544.1 - 1.9e-52 176.6 0.5 3.8e-52 175.7 0.5 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KIK65544.1 - 8.9e-06 25.6 0.7 5.9e-05 23.0 0.7 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KIK65544.1 - 0.027 14.8 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 VID27 PH-like domain Voldacs PF03517.13 KIK65544.1 - 0.31 11.1 10.6 0.44 10.7 10.6 1.6 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 KIK65544.1 - 3.1 7.0 8.6 4.4 6.5 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein Spore_coat_CotO PF14153.6 KIK65544.1 - 5.5 6.9 16.7 9.1 6.2 16.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO HA2 PF04408.23 KIK65544.1 - 7 7.0 6.1 2.8 8.3 3.3 1.8 2 0 0 2 2 2 0 Helicase associated domain (HA2) AAA_2 PF07724.14 KIK65545.1 - 3e-39 134.9 0.0 4.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KIK65545.1 - 2.4e-15 57.1 0.0 4.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIK65545.1 - 7.4e-12 45.2 0.0 1.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIK65545.1 - 2.7e-05 24.2 0.0 7.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK65545.1 - 8.7e-05 22.8 0.1 0.00053 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK65545.1 - 0.00016 21.1 0.0 0.0033 16.9 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KIK65545.1 - 0.0036 17.7 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIK65545.1 - 0.0044 16.8 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KIK65545.1 - 0.0069 16.8 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase T2SSE PF00437.20 KIK65545.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KIK65545.1 - 0.0084 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KIK65545.1 - 0.0088 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK65545.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KIK65545.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KIK65545.1 - 0.025 13.7 0.1 0.11 11.5 0.1 2.1 2 1 0 2 2 2 0 MCM P-loop domain Sigma54_activat PF00158.26 KIK65545.1 - 0.031 14.0 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIK65545.1 - 0.032 14.8 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 KIK65545.1 - 0.039 14.1 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIK65545.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK65545.1 - 0.055 14.0 0.0 0.098 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KIK65545.1 - 0.059 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase TsaE PF02367.17 KIK65545.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KIK65545.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KIK65545.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 KIK65545.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Cactin_mid PF10312.9 KIK65546.1 - 3.2e-65 219.6 3.9 3.2e-65 219.6 3.9 3.0 4 0 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KIK65546.1 - 4e-60 201.3 6.1 8.8e-60 200.1 6.1 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KIK65546.1 - 0.013 15.9 0.0 0.059 13.7 0.0 2.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) ThiF PF00899.21 KIK65548.1 - 1.4e-108 361.9 0.0 2.8e-69 233.2 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KIK65548.1 - 3.3e-88 295.8 0.0 5.9e-88 295.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KIK65548.1 - 4e-35 119.8 0.2 9.1e-35 118.7 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KIK65548.1 - 4.9e-29 100.9 1.1 1.1e-28 99.7 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KIK65548.1 - 7.6e-27 93.3 1.4 2.4e-26 91.7 1.2 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 KIK65548.1 - 0.051 13.6 0.1 0.31 11.1 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Cyclin PF08613.11 KIK65549.1 - 0.00063 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin NAGidase PF07555.13 KIK65550.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF3402 PF11882.8 KIK65551.1 - 3.4e-122 408.9 1.6 4.6e-121 405.2 1.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KIK65551.1 - 5.6e-78 262.0 0.4 9e-78 261.4 0.4 1.3 1 0 0 1 1 1 1 N1221-like protein DUF4519 PF15012.6 KIK65551.1 - 0.043 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) GIIM PF08388.11 KIK65551.1 - 0.16 12.1 0.7 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 Group II intron, maturase-specific domain CIAPIN1 PF05093.13 KIK65552.1 - 1.2e-31 109.2 3.2 1.8e-31 108.6 3.2 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KIK65552.1 - 3.1e-06 27.4 0.0 4.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus zf-HIT PF04438.16 KIK65553.1 - 1.7e-08 34.1 11.3 2.5e-08 33.6 11.3 1.2 1 0 0 1 1 1 1 HIT zinc finger Med18 PF09637.10 KIK65554.1 - 2.7e-05 24.1 0.0 0.00038 20.4 0.0 2.0 1 1 1 2 2 2 2 Med18 protein Forkhead PF00250.18 KIK65555.1 - 2.3e-26 91.9 0.0 6.5e-26 90.4 0.0 1.7 1 1 0 1 1 1 1 Forkhead domain cIII PF08134.11 KIK65555.1 - 0.036 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 cIII protein family Frizzled PF01534.17 KIK65556.1 - 0.089 11.8 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Serpentine_r_xa PF03383.15 KIK65556.1 - 0.092 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Oxidored-like PF09791.9 KIK65557.1 - 8.2e-20 70.2 0.7 1.4e-19 69.4 0.7 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal F-box-like PF12937.7 KIK65558.1 - 5.5e-05 23.0 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like XPB_DRD PF18458.1 KIK65559.1 - 0.079 12.9 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain HATPase_c PF02518.26 KIK65560.1 - 1.7e-43 147.7 0.0 9.4e-23 80.9 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK65560.1 - 1.3e-34 118.7 0.1 1e-17 64.3 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KIK65560.1 - 4.8e-22 77.8 2.1 5.6e-13 48.7 0.1 3.5 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 KIK65560.1 - 3.3e-07 30.2 0.0 2.6e-05 24.1 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KIK65560.1 - 7.8e-05 22.6 0.0 0.00078 19.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 KIK65560.1 - 0.00022 21.1 0.0 0.76 9.7 0.0 3.6 3 0 0 3 3 3 2 GHKL domain PAS_4 PF08448.10 KIK65560.1 - 0.049 13.9 0.0 0.91 9.8 0.0 2.9 3 0 0 3 3 3 0 PAS fold PAS_9 PF13426.7 KIK65560.1 - 0.19 12.0 0.0 9.4 6.5 0.0 2.8 2 1 0 2 2 2 0 PAS domain GSH_synth_ATP PF03917.17 KIK65561.1 - 2.4e-131 437.9 0.0 2.8e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KIK65561.1 - 3.3e-34 117.4 0.1 8.1e-34 116.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic glutathione synthase PrmA PF06325.13 KIK65562.1 - 9.9e-13 48.1 0.1 2.1e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KIK65562.1 - 5.3e-12 46.3 0.1 2.5e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK65562.1 - 6.9e-11 42.7 0.5 3.7e-10 40.3 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK65562.1 - 9.1e-11 41.8 0.0 2.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK65562.1 - 4.4e-07 30.6 0.4 5.5e-06 27.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK65562.1 - 5.7e-07 29.5 0.0 9.4e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK65562.1 - 8.2e-07 28.7 0.1 1.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KIK65562.1 - 0.00024 20.6 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 KIK65562.1 - 0.00047 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KIK65562.1 - 0.00058 18.9 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KIK65562.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIK65562.1 - 0.0035 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KIK65562.1 - 0.0036 17.1 0.1 0.0067 16.2 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 KIK65562.1 - 0.0047 17.0 0.0 0.0082 16.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 KIK65562.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 KIK65562.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 KIK65562.1 - 0.055 14.5 0.0 0.13 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KIK65562.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 KIK65562.1 - 0.2 11.6 0.9 0.31 11.0 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain zf-RING_5 PF14634.6 KIK65565.1 - 7.7e-05 22.6 4.3 7.7e-05 22.6 4.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain DUF5082 PF16888.5 KIK65565.1 - 0.00026 21.2 1.9 0.00039 20.7 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) zf-C3HC4_3 PF13920.6 KIK65565.1 - 0.0023 17.7 2.9 0.0058 16.5 2.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK65565.1 - 0.0024 18.1 4.4 0.0024 18.1 4.4 1.9 2 0 0 2 2 2 1 Ring finger domain zinc-ribbons_6 PF07191.12 KIK65565.1 - 0.0059 16.6 2.3 0.013 15.5 2.3 1.6 1 0 0 1 1 1 1 zinc-ribbons Prok-RING_4 PF14447.6 KIK65565.1 - 0.013 15.3 3.6 0.033 14.0 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Golgin_A5 PF09787.9 KIK65565.1 - 0.014 14.9 6.8 0.018 14.5 6.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-Nse PF11789.8 KIK65565.1 - 0.018 14.8 0.6 0.039 13.8 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KIK65565.1 - 0.022 14.6 5.2 0.059 13.2 3.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KIK65565.1 - 0.023 14.3 2.8 0.05 13.3 2.4 1.8 1 1 0 1 1 1 0 P-11 zinc finger Gin PF10764.9 KIK65565.1 - 0.026 14.5 0.3 0.8 9.7 0.0 2.4 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_4 PF14570.6 KIK65565.1 - 0.03 14.1 0.6 0.069 13.0 0.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 KIK65565.1 - 0.046 13.8 3.1 0.14 12.3 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 KIK65565.1 - 0.047 13.7 4.2 0.1 12.6 4.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon HrpB7 PF09486.10 KIK65565.1 - 0.055 13.9 3.1 0.073 13.5 3.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 KIK65565.1 - 0.098 12.2 1.8 0.13 11.8 1.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C3HC4 PF00097.25 KIK65565.1 - 0.12 12.3 2.6 0.33 10.9 2.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KIK65565.1 - 0.18 11.1 5.5 0.25 10.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TackOD1 PF18551.1 KIK65565.1 - 0.27 10.9 8.0 0.098 12.3 4.8 1.8 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-rbx1 PF12678.7 KIK65565.1 - 0.27 11.5 3.7 0.31 11.3 1.9 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain KxDL PF10241.9 KIK65565.1 - 0.35 11.2 5.7 0.75 10.1 5.7 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein zf-RING_UBOX PF13445.6 KIK65565.1 - 0.4 10.7 7.5 6.3 6.9 0.6 3.2 3 0 0 3 3 3 0 RING-type zinc-finger CENP-Q PF13094.6 KIK65565.1 - 0.76 10.0 8.2 1.1 9.4 8.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.12 KIK65565.1 - 2.2 9.0 8.9 1.6e+02 3.0 8.9 2.3 1 1 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 KIK65565.1 - 2.2 8.3 9.5 15 5.6 9.4 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MTP18 PF10558.9 KIK65567.1 - 1.4e-63 214.0 3.7 1.2e-62 210.9 3.7 1.9 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Forkhead PF00250.18 KIK65568.1 - 1.5e-25 89.3 0.0 2.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KIK65568.1 - 8.7e-06 26.0 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain IF-2B PF01008.17 KIK65569.1 - 3.4e-78 262.7 0.0 4.2e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3819 PF12842.7 KIK65569.1 - 0.099 12.6 0.2 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) ANAPC_CDC26 PF10471.9 KIK65569.1 - 0.24 12.2 5.5 0.45 11.4 5.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 MAP65_ASE1 PF03999.12 KIK65569.1 - 0.82 8.3 4.7 1.2 7.8 4.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4407 PF14362.6 KIK65569.1 - 1.3 8.3 3.9 2 7.7 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRP-alpha_N PF04086.13 KIK65569.1 - 1.9 8.3 8.0 2.8 7.8 8.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal XRN_N PF03159.18 KIK65570.1 - 1e-29 103.7 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KIK65571.1 - 0.059 12.3 0.0 0.068 12.1 0.0 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF4646 PF15496.6 KIK65572.1 - 4.2e-12 46.8 0.1 5e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4646) SR-25 PF10500.9 KIK65572.1 - 0.12 12.0 15.3 0.025 14.2 5.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Anophelin PF10731.9 KIK65572.1 - 0.87 9.5 6.2 2.2 8.2 6.2 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Topoisom_I_N PF02919.15 KIK65572.1 - 1 8.8 3.0 20 4.6 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CDC45 PF02724.14 KIK65572.1 - 1.2 7.4 8.5 0.19 10.0 0.1 2.0 2 0 0 2 2 2 0 CDC45-like protein Longin PF13774.6 KIK65573.1 - 6.8e-26 90.1 0.0 1.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KIK65573.1 - 2e-15 56.3 0.1 3.3e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin mCpol PF18182.1 KIK65573.1 - 0.034 14.5 0.0 0.75 10.1 0.0 2.3 2 1 0 2 2 2 0 minimal CRISPR polymerase domain SLM4 PF16818.5 KIK65573.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein SLM4 SKG6 PF08693.10 KIK65573.1 - 2.4 7.7 4.0 3.9 7.0 4.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF962 PF06127.11 KIK65574.1 - 9.5e-24 83.3 0.2 2.1e-23 82.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) A_deamin PF02137.18 KIK65575.1 - 3.3e-51 174.7 0.0 4.4e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Shadoo PF14999.6 KIK65576.1 - 0.029 14.5 1.4 0.041 14.0 1.4 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MRC1 PF09444.10 KIK65579.1 - 1.2e-22 80.9 27.4 1.2e-22 80.9 27.4 5.0 5 0 0 5 5 5 1 MRC1-like domain Proteasome PF00227.26 KIK65580.1 - 3.7e-55 186.4 0.1 4.4e-55 186.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK65580.1 - 5.9e-13 48.2 1.7 1.1e-12 47.4 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ACBP PF00887.19 KIK65583.1 - 2.7e-14 53.1 0.2 3.2e-11 43.3 0.1 2.4 2 0 0 2 2 2 2 Acyl CoA binding protein ADH_N PF08240.12 KIK65584.1 - 9.4e-25 86.6 1.5 2.2e-24 85.5 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK65584.1 - 7.8e-17 61.5 1.6 9.1e-17 61.3 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK65584.1 - 0.0077 15.6 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK65584.1 - 0.0087 15.4 0.5 0.018 14.4 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KIK65584.1 - 0.015 14.6 1.9 0.048 13.0 1.7 1.9 2 0 0 2 2 2 0 ThiF family CLLAC PF15675.5 KIK65584.1 - 0.47 10.1 2.5 1 8.9 2.5 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain Vfa1 PF08432.10 KIK65585.1 - 3.4e-41 141.6 7.7 3.8e-41 141.4 7.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.16 KIK65585.1 - 0.0025 17.2 9.1 0.0028 17.0 9.1 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Atrophin-1 PF03154.15 KIK65585.1 - 0.0083 14.5 15.0 0.011 14.1 15.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family Slu7 PF11708.8 KIK65585.1 - 0.0093 15.7 12.8 0.012 15.4 12.8 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor RR_TM4-6 PF06459.12 KIK65585.1 - 0.037 13.9 12.2 0.042 13.7 12.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF908 PF06012.12 KIK65585.1 - 0.059 12.8 2.9 0.069 12.6 2.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CPSF100_C PF13299.6 KIK65585.1 - 0.093 12.9 11.0 0.12 12.6 11.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Miff PF05644.11 KIK65585.1 - 0.11 12.1 3.7 0.14 11.8 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Sporozoite_P67 PF05642.11 KIK65585.1 - 0.12 10.5 7.5 0.14 10.2 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 KIK65585.1 - 0.16 11.7 9.0 0.22 11.2 9.0 1.3 1 0 0 1 1 1 0 FAM176 family PPL5 PF18168.1 KIK65585.1 - 0.16 11.2 6.6 0.21 10.9 6.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Tim54 PF11711.8 KIK65585.1 - 0.17 10.6 12.3 0.22 10.3 12.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 KIK65585.1 - 0.18 11.2 9.9 0.21 11.0 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 KIK65585.1 - 0.2 12.1 11.6 0.28 11.6 11.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Borrelia_P83 PF05262.11 KIK65585.1 - 0.21 10.0 15.6 0.23 9.9 15.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein XRCC4 PF06632.12 KIK65585.1 - 0.22 10.4 13.7 0.29 10.0 13.7 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SID-1_RNA_chan PF13965.6 KIK65585.1 - 0.25 9.7 0.2 0.29 9.5 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 KIK65585.1 - 0.25 11.5 3.6 0.27 11.4 3.6 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.15 KIK65585.1 - 0.27 10.1 1.3 0.34 9.8 1.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 KIK65585.1 - 0.36 9.8 5.8 0.37 9.8 5.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 KIK65585.1 - 0.37 9.5 5.9 0.39 9.5 5.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Roughex PF06020.11 KIK65585.1 - 0.37 9.8 9.1 0.46 9.5 9.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Rtf2 PF04641.12 KIK65585.1 - 0.46 9.8 14.8 0.64 9.3 14.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.14 KIK65585.1 - 0.51 8.6 15.7 0.6 8.3 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KIK65585.1 - 0.52 8.4 15.2 0.65 8.0 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pex14_N PF04695.13 KIK65585.1 - 0.54 10.9 7.8 0.72 10.5 7.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GNAT_acetyltr_2 PF13718.6 KIK65585.1 - 0.56 9.6 5.6 0.81 9.0 5.6 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Eapp_C PF10238.9 KIK65585.1 - 0.59 10.2 7.3 0.99 9.5 7.3 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4775 PF16001.5 KIK65585.1 - 0.64 9.4 21.6 0.83 9.0 21.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) RPN2_C PF18004.1 KIK65585.1 - 0.65 9.9 20.5 0.94 9.4 20.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 KIK65585.1 - 0.86 9.3 13.1 1.4 8.6 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NARP1 PF12569.8 KIK65585.1 - 0.99 8.2 16.6 1.2 7.9 16.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 KIK65585.1 - 1.2 8.3 5.3 1.2 8.3 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3987 PF13148.6 KIK65585.1 - 1.4 7.8 10.0 1.7 7.6 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF913 PF06025.12 KIK65585.1 - 1.5 7.8 7.6 1.7 7.5 7.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 KIK65585.1 - 1.6 7.8 9.6 2.8 7.0 9.6 1.3 1 1 0 1 1 1 0 Turkey astrovirus capsid protein RPA43_OB PF17875.1 KIK65585.1 - 1.8 9.2 7.3 2.7 8.6 7.3 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF4407 PF14362.6 KIK65585.1 - 2 7.7 4.4 2.4 7.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KIK65585.1 - 2.3 6.9 10.1 2.5 6.8 10.1 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 KIK65585.1 - 3.4 5.7 10.5 3.8 5.5 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MCM_bind PF09739.9 KIK65585.1 - 3.7 5.9 10.7 4.6 5.6 10.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 KIK65585.1 - 4.4 6.0 14.3 5.1 5.8 14.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 KIK65585.1 - 4.5 6.7 12.5 5.3 6.5 12.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2151 PF10221.9 KIK65585.1 - 5 5.6 12.3 6 5.3 12.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Paramyxo_ncap PF00973.19 KIK65585.1 - 5.3 5.8 6.2 5.5 5.8 6.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Connexin PF00029.19 KIK65585.1 - 6.3 6.5 12.0 9.6 5.9 12.0 1.3 1 0 0 1 1 1 0 Connexin MRP-S34 PF16053.5 KIK65586.1 - 8.2e-11 41.7 0.7 1.2e-10 41.2 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Glu-tRNAGln PF02686.15 KIK65587.1 - 0.00039 20.6 0.3 0.00063 20.0 0.3 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit MapZ_EC1 PF18041.1 KIK65587.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 MapZ extracellular domain 1 Glyco_hydro_88 PF07470.13 KIK65589.1 - 1.9e-19 69.9 0.9 2.8e-19 69.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Na_Ca_ex PF01699.24 KIK65590.1 - 2.4e-17 63.3 26.9 3.3e-09 36.9 13.8 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein eIF3g PF12353.8 KIK65591.1 - 1.3e-41 141.9 4.1 2.1e-41 141.2 4.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KIK65591.1 - 2.1e-18 65.9 0.1 3.4e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KIK65591.1 - 0.043 14.0 1.0 18 5.5 0.1 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KIK65591.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK65591.1 - 0.15 12.2 3.0 0.31 11.1 0.0 2.4 2 1 0 2 2 2 0 RNA binding motif Na_Ca_ex PF01699.24 KIK65592.1 - 1e-14 54.7 27.6 3.7e-08 33.5 9.6 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MBD_C PF14048.6 KIK65592.1 - 0.0039 17.9 1.5 0.0083 16.8 1.5 1.5 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 ATG_C PF09333.11 KIK65592.1 - 0.06 13.7 3.6 1.7 9.0 0.8 2.6 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain MRP-S31 PF15433.6 KIK65592.1 - 1.3 8.6 9.1 1.8 8.2 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SPATIAL PF15256.6 KIK65592.1 - 2 8.7 7.3 3.4 8.0 7.3 1.3 1 0 0 1 1 1 0 SPATIAL DUF4404 PF14357.6 KIK65592.1 - 3.3 8.4 6.3 23 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Acyltransferase PF01553.21 KIK65594.1 - 2.3e-11 43.4 0.0 2.6e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase THOC2_N PF16134.5 KIK65595.1 - 1.1e-148 496.8 0.0 1.8e-148 496.0 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KIK65595.1 - 1.4e-84 283.8 0.0 2.3e-84 283.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KIK65595.1 - 1.7e-29 101.7 0.1 4e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit COX15-CtaA PF02628.15 KIK65596.1 - 4.5e-108 361.2 8.9 5.5e-108 360.9 8.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BolA PF01722.18 KIK65597.1 - 5.2e-14 52.3 0.1 9e-14 51.5 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein Methyltransf_16 PF10294.9 KIK65598.1 - 1.6e-45 154.9 0.0 2.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 KIK65598.1 - 0.00074 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KIK65598.1 - 0.0023 17.4 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KIK65598.1 - 0.0067 16.2 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK65598.1 - 0.011 16.4 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIK65598.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AMPK1_CBM PF16561.5 KIK65600.1 - 6.7e-16 58.3 0.2 1.1e-15 57.6 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase GTP_EFTU PF00009.27 KIK65602.1 - 1.4e-32 112.8 0.0 1.6e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK65602.1 - 5.1e-14 52.5 0.0 2.2e-13 50.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KIK65602.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIK65602.1 - 0.0053 17.1 0.2 0.01 16.2 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KIK65602.1 - 0.021 14.7 0.2 0.067 13.1 0.2 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 HBS1_N PF08938.10 KIK65603.1 - 1.6e-10 41.1 1.3 4.1e-10 39.8 1.3 1.7 1 0 0 1 1 1 1 HBS1 N-terminus SSB PF00436.25 KIK65604.1 - 2.3e-18 66.1 0.0 2.9e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Haem_degrading PF03928.14 KIK65605.1 - 1.7e-09 37.8 0.0 3.9e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Haem-degrading Pex2_Pex12 PF04757.14 KIK65606.1 - 7.8e-45 153.2 5.7 9.1e-45 153.0 5.7 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIK65606.1 - 1.7e-06 27.8 0.8 2.7e-06 27.1 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK65606.1 - 1.1e-05 25.1 1.0 1.8e-05 24.5 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK65606.1 - 0.0001 22.6 0.9 0.00018 21.7 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK65606.1 - 0.0039 17.2 2.7 0.0076 16.3 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK65606.1 - 0.0059 16.5 1.2 0.0092 15.8 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK65606.1 - 0.025 14.7 2.8 0.043 14.0 2.8 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIK65606.1 - 0.042 13.7 1.9 0.67 9.9 0.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-piccolo PF05715.13 KIK65606.1 - 0.089 12.9 0.8 0.16 12.2 0.8 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger SPX PF03105.19 KIK65607.1 - 2.1e-19 70.7 3.7 1.9e-10 41.2 0.1 2.0 1 1 1 2 2 2 2 SPX domain Peripla_BP_2 PF01497.18 KIK65607.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein GDPD PF03009.17 KIK65608.1 - 0.001 18.8 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.27 KIK65609.1 - 2.1e-26 93.1 0.0 3.7e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK65609.1 - 2.4e-11 44.0 0.2 1.5e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK65609.1 - 4.8e-06 26.5 0.1 0.05 13.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KIK65609.1 - 3.8e-05 23.2 0.0 0.0045 16.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 KIK65609.1 - 0.00049 18.9 0.0 0.15 10.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KIK65609.1 - 0.0015 18.7 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KIK65609.1 - 0.0028 17.9 0.0 2.1 8.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KIK65609.1 - 0.0073 16.8 0.0 0.023 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK65609.1 - 0.021 14.6 1.7 0.025 14.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK65609.1 - 0.052 14.0 0.1 0.094 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK65609.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KIK65609.1 - 0.11 12.9 0.4 0.34 11.3 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIK65609.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 KIK65609.1 - 0.12 12.2 0.5 0.84 9.4 0.0 2.4 3 0 0 3 3 3 0 Deoxynucleoside kinase DUF87 PF01935.17 KIK65609.1 - 0.14 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIK65609.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KIK65609.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.7 KIK65609.1 - 0.18 10.7 0.0 1.2 8.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain GTP_cyclohydroI PF01227.22 KIK65611.1 - 3.9e-74 248.0 0.3 4.3e-74 247.8 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KIK65611.1 - 0.00067 19.8 0.0 0.0026 17.9 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KIK65611.1 - 0.035 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain KASH_CCD PF14662.6 KIK65612.1 - 3.5e-07 30.2 36.3 0.00097 19.0 17.5 3.0 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 KIK65612.1 - 1.7e-05 24.9 29.9 0.15 12.3 0.8 7.2 7 0 0 7 7 7 3 Homeobox associated leucine zipper ATG16 PF08614.11 KIK65612.1 - 2.5e-05 24.6 6.0 2.5e-05 24.6 6.0 3.0 1 1 2 3 3 2 1 Autophagy protein 16 (ATG16) EF-hand_4 PF12763.7 KIK65612.1 - 7.3e-05 22.7 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KIK65612.1 - 0.00039 20.8 0.0 0.015 15.7 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair YabA PF06156.13 KIK65612.1 - 0.001 19.7 26.8 0.092 13.4 0.2 4.6 1 1 3 4 4 4 1 Initiation control protein YabA bZIP_1 PF00170.21 KIK65612.1 - 0.0024 18.0 21.5 1.9 8.6 0.7 6.2 5 1 1 6 6 6 1 bZIP transcription factor DHR10 PF18595.1 KIK65612.1 - 0.0048 16.9 38.9 0.32 11.1 15.1 3.4 2 1 1 3 3 3 2 Designed helical repeat protein 10 domain DUF2968 PF11180.8 KIK65612.1 - 0.0092 15.6 12.2 0.0092 15.6 12.2 3.7 1 1 2 3 3 3 1 Protein of unknown function (DUF2968) EF-hand_10 PF14788.6 KIK65612.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 EF hand TSC22 PF01166.18 KIK65612.1 - 0.027 14.8 23.5 0.59 10.5 0.0 5.9 4 1 1 6 6 6 0 TSC-22/dip/bun family PseudoU_synth_1 PF01416.20 KIK65612.1 - 0.094 13.2 0.1 25 5.4 0.1 2.7 2 0 0 2 2 2 0 tRNA pseudouridine synthase GAS PF13851.6 KIK65612.1 - 0.099 12.0 33.6 1.2 8.5 16.2 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.13 KIK65612.1 - 0.18 11.0 35.7 0.0086 15.3 11.6 2.9 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Med9 PF07544.13 KIK65612.1 - 0.18 11.9 25.8 0.37 10.9 0.7 4.0 2 2 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Dam1 PF08653.10 KIK65612.1 - 0.18 11.6 1.6 12 5.8 0.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 PRKG1_interact PF15898.5 KIK65612.1 - 0.24 12.3 39.2 2.5 9.1 16.0 3.4 1 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 KIK65612.1 - 0.42 10.5 22.2 0.17 11.8 2.4 5.7 5 2 2 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor Rootletin PF15035.6 KIK65612.1 - 0.47 10.5 39.2 0.54 10.3 15.3 3.1 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Acetyltransf_11 PF13720.6 KIK65612.1 - 0.52 10.8 5.1 2.4 8.7 0.4 3.4 3 1 1 4 4 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 UPF0449 PF15136.6 KIK65612.1 - 0.98 9.9 0.0 0.98 9.9 0.0 5.4 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 HAMP PF00672.25 KIK65612.1 - 1.1 9.7 7.2 27 5.2 0.0 4.7 4 1 0 4 4 4 0 HAMP domain Cnn_1N PF07989.11 KIK65612.1 - 1.1 9.4 32.7 8.5 6.6 6.0 5.0 2 1 3 5 5 5 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 KIK65612.1 - 1.3 9.1 37.7 3.9 7.5 16.1 3.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.17 KIK65612.1 - 1.3 8.9 19.2 0.45 10.4 0.7 4.2 2 1 1 4 4 4 0 Prefoldin subunit DUF3573 PF12097.8 KIK65612.1 - 1.4 7.7 2.3 13 4.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) FlaC_arch PF05377.11 KIK65612.1 - 1.4 9.4 14.9 11 6.5 0.0 5.0 3 2 3 6 6 6 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KIK65612.1 - 1.5 9.2 16.3 0.46 10.8 3.2 3.9 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KIK65612.1 - 2 8.8 35.2 7 7.1 13.2 2.2 1 1 1 2 2 2 0 Fez1 NPV_P10 PF05531.12 KIK65612.1 - 2.4 8.7 7.5 2.9 8.4 0.4 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KIK65612.1 - 4 7.5 16.9 3.9 7.5 1.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KIK65612.1 - 4.2 7.2 34.0 3 7.7 2.9 6.3 2 1 4 6 6 6 0 Septum formation initiator Fib_alpha PF08702.10 KIK65612.1 - 5.3 7.2 20.5 1.8 8.8 1.1 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KIK65612.1 - 6.8 6.5 12.7 2.5 7.9 2.4 3.7 1 1 3 4 4 4 0 Phage minor structural protein GP20 ZapB PF06005.12 KIK65612.1 - 8.2 7.0 46.8 40 4.8 2.1 5.4 1 1 3 4 4 3 0 Cell division protein ZapB KxDL PF10241.9 KIK65612.1 - 8.8 6.7 23.3 0.11 12.8 1.8 4.0 2 2 2 4 4 4 0 Uncharacterized conserved protein Acetyltransf_10 PF13673.7 KIK65613.1 - 8.2e-12 45.2 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK65613.1 - 1.1e-11 45.0 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK65613.1 - 8.4e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK65613.1 - 0.00011 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIK65613.1 - 0.0017 18.5 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK65613.1 - 0.0038 17.9 0.0 0.0046 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KIK65613.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KIK65613.1 - 0.013 15.5 0.0 0.088 12.8 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KIK65613.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KIK65614.1 - 8.1e-11 42.0 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK65614.1 - 8.9e-11 42.0 0.1 1.4e-10 41.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK65614.1 - 9.6e-09 35.6 0.1 1.4e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK65614.1 - 0.00053 20.2 0.0 0.00069 19.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK65614.1 - 0.0011 19.6 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK65614.1 - 0.0025 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KIK65614.1 - 0.0061 16.3 0.1 0.01 15.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KIK65614.1 - 0.026 14.6 0.2 0.053 13.7 0.1 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_S7e PF01251.18 KIK65615.1 - 2.1e-86 288.4 3.4 2.3e-86 288.2 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.22 KIK65616.1 - 1.7e-45 154.5 0.0 7.3e-43 146.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KIK65616.1 - 1.8e-33 115.3 0.0 2.7e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK65616.1 - 8.4e-12 44.9 0.0 1.8e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK65616.1 - 8.2e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIK65616.1 - 0.00014 21.4 0.1 0.00035 20.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK65616.1 - 0.00026 20.4 0.1 0.0005 19.5 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIK65616.1 - 0.0017 18.3 0.2 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIK65616.1 - 0.0023 18.2 0.0 0.0075 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KIK65616.1 - 0.0063 16.3 0.1 0.087 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KIK65616.1 - 0.0097 16.3 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KIK65616.1 - 0.016 14.9 0.1 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KIK65616.1 - 0.065 12.5 0.1 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 KIK65616.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 KIK65616.1 - 0.1 12.1 0.0 1.9 8.0 0.0 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KIK65616.1 - 0.13 11.8 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KIK65616.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KIK65616.1 - 0.14 12.6 0.1 0.32 11.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KIK65616.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 NTPase AMMECR1 PF01871.17 KIK65617.1 - 1.6e-44 151.4 0.0 3.5e-44 150.3 0.0 1.5 1 1 0 1 1 1 1 AMMECR1 PPR_2 PF13041.6 KIK65618.1 - 2.6e-07 30.7 0.3 0.95 9.7 0.1 4.7 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.6 KIK65618.1 - 2.8e-05 24.1 0.1 0.12 12.5 0.0 3.7 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KIK65618.1 - 9.5e-05 22.4 3.3 24 5.5 0.0 5.5 4 1 1 5 5 5 2 PPR repeat PPR_1 PF12854.7 KIK65618.1 - 0.00046 19.8 5.6 0.09 12.5 0.1 4.0 4 1 0 4 4 4 2 PPR repeat Ribosomal_L3 PF00297.22 KIK65619.1 - 1.6e-187 623.0 10.6 1.8e-187 622.8 10.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 CDC27 PF09507.10 KIK65621.1 - 5.6 6.2 7.9 9.2 5.5 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPR_1 PF00515.28 KIK65624.1 - 3.8e-14 51.8 7.7 8.1e-06 25.4 1.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65624.1 - 1.9e-10 40.0 5.2 0.00042 20.2 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK65624.1 - 5.3e-08 32.5 1.5 8.7e-05 22.4 0.7 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK65624.1 - 1.4e-06 28.7 2.8 7.6e-05 23.1 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK65624.1 - 0.00022 21.5 4.4 0.054 13.8 0.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK65624.1 - 0.00036 21.1 0.4 1.4 9.6 0.1 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK65624.1 - 0.0031 18.2 1.3 0.58 11.1 0.1 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK65624.1 - 0.0043 16.7 0.2 0.45 10.2 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 KIK65624.1 - 0.024 14.8 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TEX13 PF15186.6 KIK65624.1 - 0.035 13.8 1.4 0.065 12.9 1.4 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family ANAPC3 PF12895.7 KIK65624.1 - 0.045 14.0 2.2 0.13 12.5 0.9 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK65624.1 - 0.15 12.7 2.6 3.3 8.6 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65624.1 - 0.21 11.7 2.7 18 5.7 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK65624.1 - 0.54 10.8 3.2 1.4 9.4 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 KIK65624.1 - 1.2 9.2 8.9 5.6 7.1 0.0 3.3 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain Ribosomal_L12 PF00542.19 KIK65625.1 - 2.3e-21 75.9 2.9 4.5e-20 71.8 1.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KIK65625.1 - 3e-12 46.0 13.0 3.6e-11 42.6 9.6 3.1 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Sec5 PF15469.6 KIK65625.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF3638 PF12340.8 KIK65626.1 - 1.6e-85 286.0 0.2 3e-85 285.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK65626.1 - 1.5e-16 59.5 0.1 3.9e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Not3 PF04065.15 KIK65627.1 - 6.9e-88 294.0 23.8 1.1e-87 293.3 23.8 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KIK65627.1 - 5.4e-45 152.7 7.8 5.4e-45 152.7 7.8 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MerR-DNA-bind PF09278.11 KIK65627.1 - 3 8.5 6.4 34 5.1 1.4 2.8 2 0 0 2 2 2 0 MerR, DNA binding Syntaxin_2 PF14523.6 KIK65627.1 - 4.7 7.6 13.7 0.026 14.9 3.6 2.5 3 0 0 3 3 3 0 Syntaxin-like protein DUF4407 PF14362.6 KIK65627.1 - 5.2 6.3 10.5 8.9 5.6 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 KIK65627.1 - 9.1 7.0 13.7 1.5 9.6 1.8 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) SH3_1 PF00018.28 KIK65628.1 - 2.2e-25 88.0 0.0 2.7e-11 42.9 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KIK65628.1 - 3.6e-18 65.1 0.8 6.3e-09 35.6 0.0 3.3 4 0 0 4 4 4 2 Variant SH3 domain SH3_2 PF07653.17 KIK65628.1 - 3.7e-17 61.8 0.0 7.3e-11 41.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KIK65628.1 - 1.5e-06 28.2 0.1 2.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KIK65628.1 - 0.0016 18.3 0.1 0.0037 17.1 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF5476 PF17570.2 KIK65628.1 - 0.2 12.1 1.5 0.54 10.7 1.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5476) NDUFA12 PF05071.16 KIK65629.1 - 1.7e-32 112.1 4.3 2.6e-32 111.5 4.3 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Haem_oxygenas_2 PF14518.6 KIK65629.1 - 0.053 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme DAO PF01266.24 KIK65630.1 - 9.6e-47 160.2 0.0 1.2e-46 159.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK65630.1 - 0.00015 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KIK65630.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KIK65630.1 - 0.023 13.9 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK65630.1 - 0.038 14.6 0.0 0.076 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIK65630.1 - 0.068 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cupin_7 PF12973.7 KIK65630.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain Sacchrp_dh_NADP PF03435.18 KIK65630.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Na_H_Exchanger PF00999.21 KIK65631.1 - 1e-23 83.8 23.8 1.3e-23 83.5 23.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1218 PF06749.12 KIK65632.1 - 0.26 11.8 5.1 0.12 12.9 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) 7tm_1 PF00001.21 KIK65632.1 - 0.9 8.8 8.6 0.77 9.0 1.6 2.3 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF373 PF04123.13 KIK65632.1 - 0.91 8.9 6.3 1.6 8.1 5.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF373) 7TM_GPCR_Srab PF10292.9 KIK65632.1 - 1.3 7.8 9.2 3 6.7 9.2 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor p450 PF00067.22 KIK65636.1 - 4.8e-64 216.8 0.0 5.5e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COMPASS-Shg1 PF05205.12 KIK65637.1 - 1.9e-09 38.1 0.8 3.6e-09 37.3 0.8 1.5 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Spore_coat_CotO PF14153.6 KIK65637.1 - 0.33 10.9 8.0 0.5 10.3 8.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Ndc1_Nup PF09531.10 KIK65637.1 - 7.6 5.1 8.8 12 4.5 8.8 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 KIK65637.1 - 9.9 4.9 9.4 12 4.5 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) URO-D PF01208.17 KIK65638.1 - 3.1e-129 431.1 0.0 3.5e-129 430.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Kinesin PF00225.23 KIK65639.1 - 3.1e-85 286.1 0.2 8e-85 284.7 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIK65639.1 - 2.8e-15 56.5 0.0 5.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF357 PF04010.13 KIK65639.1 - 0.18 11.9 0.1 0.52 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DSPn PF14671.6 KIK65640.1 - 1.8e-42 145.1 0.0 9e-40 136.4 0.0 2.8 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KIK65640.1 - 4.3e-16 58.9 0.0 8.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK65640.1 - 0.00089 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK65640.1 - 0.0013 18.8 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate ANTH PF07651.16 KIK65640.1 - 0.033 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Bac_surface_Ag PF01103.23 KIK65641.1 - 8.9e-38 130.6 0.4 1.1e-37 130.3 0.4 1.1 1 0 0 1 1 1 1 Surface antigen OmpA_membrane PF01389.17 KIK65641.1 - 0.15 11.8 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 OmpA-like transmembrane domain Ank_2 PF12796.7 KIK65642.1 - 3.8e-18 65.9 0.0 3.1e-09 37.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK65642.1 - 8.3e-17 61.3 1.5 2.5e-09 37.5 0.0 4.5 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KIK65642.1 - 2.9e-16 59.1 0.6 2.3e-06 27.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIK65642.1 - 2.7e-13 49.8 0.3 4.7e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK65642.1 - 8.9e-13 47.2 0.2 0.00014 22.0 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KIK65642.1 - 0.00022 21.1 0.1 0.0021 17.9 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Sec34 PF04136.15 KIK65642.1 - 0.021 14.7 1.8 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Sec34-like family CENP-Q PF13094.6 KIK65642.1 - 0.031 14.5 1.6 0.059 13.6 0.8 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit KxDL PF10241.9 KIK65642.1 - 0.13 12.5 0.1 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 KIK65642.1 - 0.41 10.9 3.3 1.9 8.7 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nucleoside_tran PF01733.18 KIK65644.1 - 1.5e-36 126.4 7.1 3.3e-36 125.2 7.1 1.5 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KIK65646.1 - 1.4e-29 103.1 36.5 1.4e-29 103.1 36.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5089 PF17002.5 KIK65646.1 - 0.063 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) HpcH_HpaI PF03328.14 KIK65647.1 - 2.1e-38 131.7 0.0 2.7e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MafB PF06255.13 KIK65647.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Neisseria toxin MafB ADH_N PF08240.12 KIK65650.1 - 1.6e-30 105.2 3.3 2.7e-30 104.4 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK65650.1 - 7.5e-18 64.8 0.1 7.5e-18 64.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK65650.1 - 5.2e-08 34.0 0.0 1.1e-07 32.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK65650.1 - 3.6e-06 26.6 0.4 0.00051 19.6 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KIK65650.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF5559 PF17714.1 KIK65650.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5559) Fungal_trans PF04082.18 KIK65651.1 - 2.6e-33 115.2 0.1 1e-32 113.2 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK65651.1 - 5.1e-09 36.1 9.8 1.4e-08 34.7 9.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PARP PF00645.18 KIK65652.1 - 9.9e-24 84.0 1.1 1e-23 83.9 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FAM176 PF14851.6 KIK65653.1 - 0.06 13.0 3.7 0.059 13.0 3.7 1.1 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 KIK65653.1 - 0.69 9.9 5.7 0.79 9.7 5.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 KIK65653.1 - 0.78 9.5 11.8 0.87 9.3 11.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KIK65653.1 - 1.3 8.3 10.4 1.4 8.1 10.4 1.0 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 KIK65653.1 - 2.3 7.0 6.4 2.4 6.9 6.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3464 PF11947.8 KIK65653.1 - 3 7.6 5.8 3.4 7.4 5.8 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4820 PF16091.5 KIK65653.1 - 5.2 6.4 6.0 5.3 6.3 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PBP1_TM PF14812.6 KIK65653.1 - 8.7 6.8 16.6 48 4.4 16.7 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytomega_UL84 PF06284.11 KIK65653.1 - 9.1 4.6 7.9 8.9 4.6 7.9 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3836 PF12930.7 KIK65654.1 - 0.0082 15.9 0.2 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF3836) FAD_binding_3 PF01494.19 KIK65655.1 - 5.2e-19 68.7 0.8 2.7e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK65655.1 - 1.1e-06 28.7 0.6 2.8e-06 27.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK65655.1 - 1.8e-06 27.3 0.4 2.4e-06 26.8 0.4 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK65655.1 - 1.3e-05 24.6 0.1 6.3e-05 22.3 0.3 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK65655.1 - 2.9e-05 23.8 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK65655.1 - 0.00073 19.0 1.2 0.0011 18.4 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK65655.1 - 0.0026 16.9 1.6 0.0026 16.9 1.6 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KIK65655.1 - 0.0057 15.8 1.1 0.0091 15.1 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIK65655.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KIK65655.1 - 0.026 13.4 0.6 0.79 8.5 0.5 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 KIK65655.1 - 0.027 15.0 1.5 0.064 13.8 1.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK65655.1 - 0.073 12.3 1.3 0.096 12.0 0.2 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KIK65655.1 - 0.091 11.4 1.6 0.13 11.0 1.6 1.4 1 1 0 1 1 1 0 HI0933-like protein Abhydrolase_6 PF12697.7 KIK65656.1 - 5.9e-10 40.1 0.0 1.8e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK65656.1 - 0.0013 18.4 0.0 0.004 16.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.8 KIK65656.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Aldo_ket_red PF00248.21 KIK65658.1 - 2.8e-68 230.3 0.0 3.2e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GIIM PF08388.11 KIK65658.1 - 0.054 13.5 0.6 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Group II intron, maturase-specific domain Kelch_4 PF13418.6 KIK65660.1 - 2.2e-39 133.2 13.3 4e-06 26.7 0.2 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK65660.1 - 5.8e-36 121.6 8.1 2.7e-07 30.6 0.0 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KIK65660.1 - 2.9e-35 119.6 11.0 8.8e-08 31.6 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 KIK65660.1 - 3.9e-35 119.3 9.3 3.5e-08 33.3 0.3 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KIK65660.1 - 3.2e-27 93.4 8.6 3.5e-05 23.6 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KIK65660.1 - 8.5e-26 89.7 20.1 8.5e-06 25.9 0.1 7.9 6 2 0 6 6 6 5 Galactose oxidase, central domain SET PF00856.28 KIK65661.1 - 2.4e-17 63.8 0.0 2.4e-17 63.8 0.0 2.5 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.16 KIK65661.1 - 2.4e-08 34.6 1.2 6.4e-06 26.8 1.2 2.7 1 1 0 1 1 1 1 Pre-SET motif Nic96 PF04097.14 KIK65662.1 - 2.9e-128 429.0 0.0 1.8e-94 317.4 0.0 2.2 1 1 0 2 2 2 2 Nup93/Nic96 BAR PF03114.18 KIK65662.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 BAR domain WD40 PF00400.32 KIK65663.1 - 0.00043 21.0 7.3 1.2 10.1 0.6 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat PGI PF00342.19 KIK65664.1 - 0.061 11.9 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase MS_channel PF00924.18 KIK65665.1 - 2.3e-14 53.4 0.7 3.8e-14 52.7 0.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIK65665.1 - 0.00024 20.4 0.0 0.00048 19.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIK65665.1 - 0.00066 19.4 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KIK65665.1 - 0.00067 19.0 0.1 0.0015 18.0 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KIK65665.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair TMEM151 PF14857.6 KIK65665.1 - 0.12 11.3 0.5 0.18 10.7 0.5 1.2 1 0 0 1 1 1 0 TMEM151 family EI24 PF07264.11 KIK65665.1 - 0.53 10.5 16.9 2 8.6 12.0 2.5 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) adh_short_C2 PF13561.6 KIK65667.1 - 6.1e-55 186.3 0.0 7.9e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK65667.1 - 1.1e-41 142.5 0.0 1.4e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK65667.1 - 8e-05 22.6 0.2 0.00011 22.2 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK65667.1 - 0.025 14.5 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KIK65668.1 - 3.4e-20 72.3 0.0 4.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK65668.1 - 1.5e-15 57.4 0.0 2.1e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mpt_N PF09176.11 KIK65668.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Sod_Fe_C PF02777.18 KIK65669.1 - 1.9e-14 53.6 0.1 1.1e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Med15 PF09606.10 KIK65669.1 - 0.014 14.1 8.0 0.018 13.8 8.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOG2 PF10428.9 KIK65669.1 - 0.91 8.7 6.1 1.1 8.4 6.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DAD PF02109.16 KIK65670.1 - 1.1e-47 160.8 4.5 1.4e-47 160.5 4.5 1.0 1 0 0 1 1 1 1 DAD family UvdE PF03851.14 KIK65670.1 - 0.15 11.2 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 UV-endonuclease UvdE DUF1748 PF08520.10 KIK65671.1 - 2.6e-27 94.5 0.0 2.9e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Hexokinase_2 PF03727.16 KIK65672.1 - 5.7e-75 251.8 0.0 1.3e-43 149.1 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KIK65672.1 - 2.9e-66 223.2 0.0 4.1e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 KIK65672.1 - 0.0038 17.3 0.4 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0270) IPK PF03770.16 KIK65674.1 - 1.3e-34 119.8 0.0 1.3e-33 116.5 0.0 2.6 2 1 0 2 2 2 1 Inositol polyphosphate kinase TFIIA PF03153.13 KIK65674.1 - 0.011 15.8 5.6 0.02 14.9 5.4 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc4 PF05132.14 KIK65674.1 - 0.024 15.1 0.3 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 LAT PF15234.6 KIK65674.1 - 0.027 14.2 3.9 0.053 13.2 3.9 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Sporozoite_P67 PF05642.11 KIK65674.1 - 0.054 11.6 6.8 0.0073 14.5 3.0 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF913 PF06025.12 KIK65674.1 - 0.067 12.2 1.4 0.077 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KIK65674.1 - 0.091 11.0 4.5 0.15 10.3 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1115 PF06544.12 KIK65674.1 - 0.1 12.7 0.3 0.22 11.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) COPI_C PF06957.11 KIK65674.1 - 0.87 8.3 4.6 1.4 7.6 4.6 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DNA_pol_phi PF04931.13 KIK65674.1 - 1.6 6.7 10.3 2.4 6.2 10.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 KIK65674.1 - 1.9 8.1 13.2 0.081 12.6 6.8 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 KIK65674.1 - 3.2 7.4 8.5 0.41 10.3 4.2 1.7 2 0 0 2 2 2 0 FAM176 family Mob1_phocein PF03637.17 KIK65675.1 - 8.1e-23 81.3 0.0 1.3e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Aft1_HRA PF11786.8 KIK65676.1 - 1.8e-16 60.2 16.7 1.8e-16 60.2 16.7 3.4 2 1 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 KIK65676.1 - 1.8e-10 40.8 9.5 3.4e-10 39.9 9.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK65676.1 - 5.8e-06 26.3 8.2 1.3e-05 25.2 8.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 KIK65676.1 - 0.04 13.9 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Aft1_OSA PF11785.8 KIK65676.1 - 1.6 9.2 24.5 0.031 14.7 14.7 3.0 2 1 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.17 KIK65676.1 - 2.3 8.8 10.2 0.43 11.1 6.0 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor zf-RING_11 PF17123.5 KIK65677.1 - 1.1e-10 41.0 11.0 2e-10 40.2 11.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger FHA PF00498.26 KIK65677.1 - 1.2e-10 41.6 0.1 2.3e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 KIK65677.1 - 1.8e-07 31.3 17.0 3.2e-07 30.6 17.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KIK65677.1 - 0.0022 18.0 1.9 0.0037 17.3 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KIK65677.1 - 0.0069 16.2 16.9 0.012 15.5 16.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK65677.1 - 0.011 15.7 15.0 0.018 15.0 15.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KIK65677.1 - 0.015 15.6 10.7 0.036 14.3 10.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIK65677.1 - 0.042 13.7 17.5 0.069 13.0 17.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK65677.1 - 0.1 12.7 17.7 0.22 11.6 17.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 KIK65677.1 - 6.7 6.7 11.2 13 5.8 11.2 1.5 1 0 0 1 1 1 0 PHD-finger Asp5 PF17000.5 KIK65678.1 - 2.5 8.3 4.2 0.67 10.1 0.1 2.2 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 MARVEL PF01284.23 KIK65680.1 - 4.8e-07 29.9 17.0 4.8e-07 29.9 17.0 1.5 2 0 0 2 2 2 1 Membrane-associating domain DUF2070 PF09843.9 KIK65680.1 - 7.9 4.6 12.5 9.8 4.3 12.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF996 PF06195.13 KIK65680.1 - 8.3 6.7 15.5 2 8.7 9.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF996) EIIBC-GUT_C PF07663.11 KIK65681.1 - 0.031 14.4 0.7 0.54 10.4 0.0 2.5 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus MARVEL PF01284.23 KIK65681.1 - 0.038 14.0 23.3 0.056 13.5 19.8 2.0 1 1 1 2 2 2 0 Membrane-associating domain DUF2070 PF09843.9 KIK65681.1 - 5.6 5.1 11.1 7.1 4.8 11.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) p450 PF00067.22 KIK65683.1 - 1.3e-48 166.0 0.0 1.8e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PUF PF00806.19 KIK65684.1 - 7.9e-18 63.1 0.0 7e-05 22.3 0.0 5.9 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat ParA PF10609.9 KIK65685.1 - 4e-87 291.7 0.0 4.9e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK65685.1 - 4.8e-07 29.9 0.0 1.3e-06 28.4 0.0 1.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK65685.1 - 3.3e-06 26.5 0.3 0.00033 20.0 0.2 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 KIK65685.1 - 3.4e-06 27.1 0.0 0.004 17.1 0.1 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KIK65685.1 - 0.001 18.5 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 KIK65685.1 - 0.058 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK65685.1 - 0.082 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 KIK65685.1 - 0.084 12.3 0.0 0.39 10.2 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KIK65685.1 - 0.087 12.7 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase F-box-like PF12937.7 KIK65686.1 - 1.9e-07 30.9 1.5 3.1e-06 27.0 0.1 2.7 2 0 0 2 2 2 1 F-box-like GN3L_Grn1 PF08701.11 KIK65687.1 - 1.2e-22 79.7 17.2 4.4e-22 78.0 17.2 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KIK65687.1 - 2e-13 50.4 0.5 2.6e-11 43.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK65687.1 - 1.9e-08 34.4 0.0 1e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KIK65687.1 - 7.5e-08 31.9 0.1 1.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KIK65687.1 - 2.7e-05 23.6 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 KIK65687.1 - 9.3e-05 22.0 0.0 0.0048 16.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIK65687.1 - 0.00015 21.9 0.6 0.00015 21.9 0.6 3.6 4 1 0 4 4 4 1 Dynamin family GTP_EFTU PF00009.27 KIK65687.1 - 0.00079 19.0 0.1 1.9 8.0 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK65687.1 - 0.014 15.6 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GBP PF02263.19 KIK65687.1 - 0.038 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain IIGP PF05049.13 KIK65687.1 - 0.04 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) BUD22 PF09073.10 KIK65687.1 - 0.82 8.9 30.7 0.43 9.9 12.5 2.3 2 0 0 2 2 2 0 BUD22 CNDH2_C PF16858.5 KIK65687.1 - 1 9.2 21.5 0.57 10.0 7.2 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 KIK65687.1 - 9.5 4.3 29.8 0.0089 14.3 13.2 2.2 2 0 0 2 2 2 0 Nop14-like family RRM_1 PF00076.22 KIK65688.1 - 1.5e-16 60.0 0.0 2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK65688.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18 PF17135.4 KIK65689.1 - 6.5e-88 293.0 0.8 7.2e-88 292.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KIK65689.1 - 0.12 13.1 0.0 0.12 13.1 0.0 2.0 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Con-6 PF10346.9 KIK65691.1 - 1.1e-13 51.0 0.1 1.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Conidiation protein 6 DUF4658 PF15555.6 KIK65691.1 - 3.5 7.8 6.6 0.54 10.4 3.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) DUF3445 PF11927.8 KIK65692.1 - 1.2e-68 231.2 0.0 1.5e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Plasmid_stab_B PF10784.9 KIK65693.1 - 0.062 13.1 0.1 5.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Plasmid stability protein Plasmid_stab_B PF10784.9 KIK65694.1 - 0.084 12.7 0.1 6.5 6.7 0.0 2.4 1 1 1 2 2 2 0 Plasmid stability protein MBOAT PF03062.19 KIK65695.1 - 2.9e-38 132.1 4.6 5e-38 131.3 3.8 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pex2_Pex12 PF04757.14 KIK65695.1 - 0.026 14.1 0.6 0.026 14.1 0.6 1.9 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Abhydrolase_6 PF12697.7 KIK65696.1 - 1.2e-09 39.1 1.3 6.3e-09 36.8 1.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase3_N PF03893.16 KIK65696.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase 3 N-terminal region Isochorismatase PF00857.20 KIK65697.1 - 2.5e-07 31.0 0.3 3.4e-07 30.6 0.3 1.4 1 1 0 1 1 1 1 Isochorismatase family Abhydrolase_6 PF12697.7 KIK65698.1 - 9.4e-12 46.0 4.1 7.6e-10 39.8 4.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Isochorismatase PF00857.20 KIK65699.1 - 8.7e-22 78.1 0.2 1.3e-21 77.5 0.2 1.3 1 0 0 1 1 1 1 Isochorismatase family TPP_enzyme_M PF00205.22 KIK65699.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ATG16 PF08614.11 KIK65700.1 - 0.0014 18.9 11.5 0.0014 18.9 11.5 2.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KIK65700.1 - 4.4 4.7 17.9 0.025 12.1 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PDCD2_C PF04194.13 KIK65701.1 - 9.8e-41 139.7 0.1 1.3e-40 139.4 0.1 1.1 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain B12D PF06522.11 KIK65703.1 - 5.3e-12 45.4 0.1 7.3e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 KIK65704.1 - 7e-11 41.8 0.2 9.6e-11 41.3 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.21 KIK65705.1 - 9.6e-42 143.2 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_9 PF13371.6 KIK65707.1 - 9e-05 22.6 0.1 0.00016 21.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65707.1 - 0.00021 21.1 0.1 0.00039 20.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK65707.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Torus PF16131.5 KIK65707.1 - 0.024 15.3 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 Torus domain DUF676 PF05057.14 KIK65708.1 - 8.8e-39 133.3 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KIK65708.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Med26 PF08711.11 KIK65709.1 - 8.9e-10 38.5 0.7 1.7e-09 37.5 0.7 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 KIK65709.1 - 1.7e-06 27.8 4.1 2.7e-06 27.1 4.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK65709.1 - 2.8e-06 27.0 3.1 4.2e-06 26.4 3.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIK65709.1 - 1.3e-05 25.1 5.6 2.1e-05 24.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KIK65709.1 - 0.02 15.6 1.0 0.045 14.4 1.0 1.5 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KIK65709.1 - 1.1 9.8 3.1 1.8 9.2 3.1 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HMG_box PF00505.19 KIK65710.1 - 2.3e-18 66.4 2.4 5.2e-18 65.2 2.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK65710.1 - 8.2e-13 48.8 1.9 2.3e-12 47.3 1.9 1.8 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KIK65710.1 - 0.034 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain Protamine_like PF06382.11 KIK65710.1 - 0.46 10.6 7.3 0.041 14.1 1.7 2.1 2 1 1 3 3 3 0 Protamine and protamine like AT_hook PF02178.19 KIK65712.1 - 0.0036 17.0 38.3 0.27 11.2 2.6 5.7 5 0 0 5 5 5 4 AT hook motif Adap_comp_sub PF00928.21 KIK65713.1 - 5.5e-56 189.9 0.0 7e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK65713.1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain F-box-like PF12937.7 KIK65714.1 - 4.5e-07 29.6 0.4 2.9e-06 27.1 0.4 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK65716.1 - 0.14 12.7 4.8 15 6.2 1.1 4.4 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK65716.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.3 3 0 0 3 3 3 0 F-box-like STI1 PF17830.1 KIK65717.1 - 2e-16 59.6 0.6 3.4e-16 58.9 0.6 1.4 1 0 0 1 1 1 1 STI1 domain TPR_1 PF00515.28 KIK65717.1 - 5.2e-13 48.2 0.8 7.2e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65717.1 - 9e-11 41.0 0.3 3.3e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK65717.1 - 4.7e-08 32.6 0.1 3.3e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_19 PF14559.6 KIK65717.1 - 6.4e-08 33.0 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65717.1 - 1.2e-07 31.2 0.9 2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK65717.1 - 1.5e-07 31.1 0.2 0.00026 21.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK65717.1 - 2.5e-07 31.2 0.0 4.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK65717.1 - 2.3e-06 27.8 0.2 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK65717.1 - 3.5e-06 27.4 0.0 0.017 15.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK65717.1 - 4.8e-06 26.9 0.7 0.085 13.5 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK65717.1 - 0.00019 21.2 0.1 0.0072 16.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 KIK65717.1 - 0.00031 20.7 1.1 0.008 16.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK65717.1 - 0.0015 18.8 0.0 0.011 16.1 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK65717.1 - 0.0033 16.9 1.9 0.013 14.9 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR ANAPC3 PF12895.7 KIK65717.1 - 0.026 14.7 0.1 0.073 13.3 0.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 KIK65717.1 - 0.06 12.8 0.5 4.3 6.7 0.0 2.4 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_9 PF13371.6 KIK65717.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Hypoth_Ymh PF09509.10 KIK65717.1 - 0.13 12.2 0.3 0.47 10.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (Hypoth_ymh) MscS_porin PF12795.7 KIK65717.1 - 0.27 10.8 1.9 0.54 9.8 0.4 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TPR_2 PF07719.17 KIK65718.1 - 3.3e-09 36.2 0.9 0.00016 21.5 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK65718.1 - 4.6e-08 32.6 0.9 6e-05 22.7 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK65718.1 - 5.2e-05 23.5 0.1 2.2 8.6 0.0 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK65718.1 - 0.00041 20.1 0.1 0.078 12.9 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK65718.1 - 0.00078 19.1 0.4 0.0017 18.0 0.1 1.7 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 KIK65718.1 - 0.0058 17.3 0.3 0.015 15.9 0.3 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK65718.1 - 0.0074 17.0 0.1 0.093 13.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK65718.1 - 0.015 15.3 0.1 1.3 9.2 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK65718.1 - 0.017 15.6 0.9 0.089 13.3 0.2 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK65718.1 - 0.056 14.1 0.4 2.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIK65718.1 - 0.061 13.8 0.0 0.076 13.5 0.0 1.1 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Fungal_trans PF04082.18 KIK65721.1 - 6.2e-14 51.7 2.5 1.3e-13 50.6 2.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK65721.1 - 3.6e-05 23.8 9.2 6.5e-05 23.0 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.8 KIK65722.1 - 8.9e-33 113.7 0.0 2.9e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 TPR_16 PF13432.6 KIK65722.1 - 0.014 16.0 0.7 0.55 10.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK65722.1 - 0.037 14.6 1.5 2.4 9.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK65722.1 - 0.07 14.0 0.5 38 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK65722.1 - 0.1 13.1 0.0 21 5.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 KIK65725.1 - 1.7e-11 44.1 0.2 2.7e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PBP PF01161.20 KIK65727.1 - 1.5e-10 41.5 0.1 7.1e-10 39.3 0.1 1.9 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 KIK65728.1 - 5.6e-14 52.6 0.0 8.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RGS PF00615.19 KIK65729.1 - 1.1e-37 129.0 0.1 4.3e-37 127.0 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KIK65729.1 - 1.1e-10 41.4 0.0 9.2e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mrr_N PF14338.6 KIK65729.1 - 0.043 13.9 0.1 24 5.2 0.0 3.2 3 0 0 3 3 3 0 Mrr N-terminal domain DUF2458 PF10454.9 KIK65732.1 - 7.2e-07 29.0 1.2 1.6e-06 27.9 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 KIK65732.1 - 0.0084 15.8 1.1 0.021 14.5 1.1 1.6 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein ABC2_membrane_3 PF12698.7 KIK65732.1 - 0.046 12.8 0.2 0.068 12.3 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Abhydrolase_1 PF00561.20 KIK65733.1 - 0.0016 18.1 0.1 0.26 10.9 0.1 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold GDP_Man_Dehyd PF16363.5 KIK65734.1 - 9.2e-61 206.1 0.0 1.2e-60 205.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK65734.1 - 3.7e-47 160.8 0.0 5.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK65734.1 - 1.3e-07 31.0 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK65734.1 - 7.7e-07 28.5 0.1 0.0065 15.7 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KIK65734.1 - 8.6e-06 25.1 0.0 0.0025 17.0 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIK65734.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Bystin PF05291.11 KIK65735.1 - 5.7e-127 423.0 0.0 5.7e-127 423.0 0.0 1.4 2 0 0 2 2 2 1 Bystin Nop14 PF04147.12 KIK65735.1 - 0.11 10.6 15.7 0.15 10.2 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 KIK65735.1 - 0.65 8.9 7.5 0.89 8.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 KIK65735.1 - 2.3 6.2 14.3 3.3 5.7 14.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KIK65735.1 - 5.7 6.6 17.4 9.5 5.9 17.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_79C PF16862.5 KIK65736.1 - 3.7e-14 53.5 0.3 1e-13 52.1 0.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain UPF0051 PF01458.17 KIK65736.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) Abhydrolase_6 PF12697.7 KIK65737.1 - 1.3e-11 45.6 0.5 6.8e-10 39.9 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cyclin PF08613.11 KIK65740.1 - 5.4e-42 143.9 0.9 6.1e-42 143.7 0.9 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIK65740.1 - 0.029 14.1 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain ERG2_Sigma1R PF04622.12 KIK65741.1 - 8.9e-100 332.3 0.0 1e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pkinase_fungal PF17667.1 KIK65746.1 - 1.5e-56 192.0 0.0 2.8e-56 191.1 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK65746.1 - 3.5e-07 29.9 0.1 1.4e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65746.1 - 0.047 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 KIK65746.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRKCSH-like PF12999.7 KIK65747.1 - 1e-47 162.2 1.6 1e-47 162.2 1.6 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KIK65747.1 - 3.2e-26 91.9 0.3 6.5e-26 90.9 0.3 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KIK65747.1 - 2.5e-09 38.0 0.3 2.5e-09 38.0 0.3 2.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein DUF1612 PF07756.12 KIK65747.1 - 0.2 11.9 4.0 1.3 9.3 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) Ldl_recept_a PF00057.18 KIK65747.1 - 0.27 11.5 18.1 0.14 12.4 3.9 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A TMCO5 PF14992.6 KIK65747.1 - 6 6.4 7.5 4 6.9 0.2 2.3 2 0 0 2 2 2 0 TMCO5 family Ribosomal_S25 PF03297.15 KIK65748.1 - 2.3e-37 127.2 4.1 2.6e-37 127.1 4.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KIK65748.1 - 0.0018 17.8 0.5 0.003 17.1 0.5 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIK65748.1 - 0.064 13.2 0.1 0.085 12.8 0.1 1.2 1 0 0 1 1 1 0 MarR family FtsK_gamma PF09397.10 KIK65748.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Ftsk gamma domain Transferase PF02458.15 KIK65749.1 - 4.9e-31 107.8 0.0 2.1e-30 105.8 0.0 1.9 1 1 0 1 1 1 1 Transferase family FGGY_C PF02782.16 KIK65750.1 - 6.1e-45 153.4 0.0 9.1e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIK65750.1 - 1.9e-21 76.7 0.1 1.4e-20 73.9 0.0 2.5 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KIK65750.1 - 0.0013 18.3 0.1 0.0081 15.7 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Geminin PF07412.12 KIK65750.1 - 0.01 15.6 0.1 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Geminin Hexokinase_1 PF00349.21 KIK65750.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Hexokinase bZIP_2 PF07716.15 KIK65751.1 - 5.6e-12 45.6 9.3 5.6e-12 45.6 9.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK65751.1 - 6.8e-10 38.9 8.9 6.8e-10 38.9 8.9 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KIK65751.1 - 0.02 15.4 6.9 0.02 15.4 6.9 2.1 1 1 2 3 3 3 0 bZIP Maf transcription factor Chibby PF14645.6 KIK65751.1 - 0.021 15.2 1.8 0.03 14.7 1.8 1.2 1 0 0 1 1 1 0 Chibby family M PF02370.16 KIK65751.1 - 0.18 12.5 3.3 0.55 11.0 2.4 2.4 1 1 0 1 1 1 0 M protein repeat SH3_9 PF14604.6 KIK65752.1 - 5.1e-14 51.9 0.1 7.9e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK65752.1 - 5.1e-13 48.4 0.1 8e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK65752.1 - 1.3e-10 40.8 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain NAD_binding_4 PF07993.12 KIK65753.1 - 1.2e-34 119.7 0.0 2.3e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK65753.1 - 1.1e-30 106.6 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK65753.1 - 1.6e-06 27.8 0.0 5e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK65753.1 - 0.00016 21.6 0.0 0.00079 19.4 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding PP-binding PF00550.25 KIK65753.1 - 0.00059 20.1 0.1 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site peroxidase PF00141.23 KIK65754.1 - 4.5e-23 82.2 0.0 6.8e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3546 PF12066.8 KIK65755.1 - 4.8e-15 55.7 1.2 1.6e-14 54.1 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KIK65755.1 - 1.3e-14 55.0 0.1 6.2e-14 52.8 0.1 2.2 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KIK65755.1 - 0.00018 21.2 3.4 0.00046 19.9 3.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 KIK65755.1 - 0.33 11.5 4.6 0.34 11.4 1.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Response_reg PF00072.24 KIK65756.1 - 4.8e-22 78.2 0.1 3e-16 59.6 0.2 2.6 2 0 0 2 2 2 2 Response regulator receiver domain F-box-like PF12937.7 KIK65757.1 - 0.0003 20.6 1.8 0.00068 19.5 1.8 1.6 1 0 0 1 1 1 1 F-box-like NAD_binding_4 PF07993.12 KIK65759.1 - 1.6e-31 109.5 0.0 2.6e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK65759.1 - 7.6e-31 107.1 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK65759.1 - 3.8e-05 23.3 0.0 7.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK65759.1 - 0.00018 21.8 0.0 0.00051 20.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ribosomal_L2_C PF03947.18 KIK65760.1 - 2.5e-47 160.2 2.4 4.6e-47 159.3 2.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIK65760.1 - 6.7e-15 54.8 0.1 1.8e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SGL PF08450.12 KIK65761.1 - 0.00015 21.4 0.0 0.0073 15.9 0.0 2.5 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 KIK65762.1 - 0.00015 21.4 0.0 0.013 15.1 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region JmjC PF02373.22 KIK65763.1 - 2.1e-11 44.2 0.0 6.3e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIK65763.1 - 0.00021 21.1 0.0 0.0019 18.0 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain Pkinase PF00069.25 KIK65766.1 - 1.1e-49 169.2 0.0 1.3e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65766.1 - 8.7e-25 87.5 0.0 1e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KIK65766.1 - 0.00074 19.2 0.0 0.062 12.9 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK65766.1 - 0.064 13.2 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK65766.1 - 0.19 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfotransfer_3 PF13469.6 KIK65767.1 - 0.0043 17.5 0.1 0.03 14.7 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family Peptidase_C12 PF01088.21 KIK65768.1 - 1.1e-53 182.1 0.0 1.2e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_28 PF00295.17 KIK65770.1 - 2e-39 135.5 11.2 2.9e-39 135.0 11.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIK65770.1 - 0.0023 17.8 15.9 0.0023 17.8 15.9 2.8 1 1 1 2 2 2 1 Right handed beta helix region F-box-like PF12937.7 KIK65771.1 - 2.2e-07 30.6 4.8 1.1e-06 28.4 2.5 2.6 2 0 0 2 2 2 1 F-box-like Csm1_N PF18504.1 KIK65771.1 - 0.16 12.3 0.1 0.33 11.3 0.1 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain LRR_4 PF12799.7 KIK65771.1 - 0.44 11.0 5.8 12 6.4 0.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK65771.1 - 0.77 9.7 7.5 39 4.3 7.5 3.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIK65772.1 - 1.2e-07 31.5 6.9 3.8e-07 29.9 6.9 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK65772.1 - 0.00061 19.6 4.0 0.46 10.4 0.1 2.4 2 1 1 3 3 3 2 F-box domain F-box-like PF12937.7 KIK65773.1 - 1.3e-06 28.2 3.0 6.9e-06 25.9 3.0 2.4 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK65774.1 - 2.8e-10 39.9 2.9 1.8e-09 37.3 0.6 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK65774.1 - 0.0013 18.5 7.5 0.034 14.1 5.2 3.1 2 1 0 2 2 2 1 F-box domain MscS_porin PF12795.7 KIK65774.1 - 0.0033 17.0 0.1 0.0046 16.5 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DHR10 PF18595.1 KIK65774.1 - 0.046 13.8 0.4 0.069 13.2 0.4 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 KIK65774.1 - 0.14 12.1 0.1 0.22 11.5 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit Abhydrolase_1 PF00561.20 KIK65775.1 - 1.1e-20 74.4 0.0 1.6e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK65775.1 - 1e-12 49.2 0.0 1.3e-12 48.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK65775.1 - 9.5e-12 44.7 0.0 1.6e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KIK65775.1 - 0.0011 18.6 0.0 0.0033 17.0 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KIK65775.1 - 0.064 12.7 0.0 0.24 10.9 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KIK65775.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 KIK65775.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family TMEM154 PF15102.6 KIK65776.1 - 0.022 14.7 0.6 0.022 14.7 0.6 1.6 2 0 0 2 2 2 0 TMEM154 protein family RHSP PF07999.11 KIK65779.1 - 0.00022 20.2 1.8 0.016 14.0 1.8 2.0 1 1 0 1 1 1 1 Retrotransposon hot spot protein AAA_16 PF13191.6 KIK65779.1 - 0.00062 20.2 0.0 0.00079 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DASH_Dad4 PF08650.10 KIK65779.1 - 0.024 14.6 0.5 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad4 RNA_helicase PF00910.22 KIK65779.1 - 0.12 12.8 0.0 0.53 10.7 0.0 2.1 2 1 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KIK65779.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein WD40_4 PF16300.5 KIK65781.1 - 5.3e-07 29.4 0.1 5.3e-07 29.4 0.1 2.2 2 1 0 2 2 2 1 Type of WD40 repeat MRFAP1 PF15155.6 KIK65781.1 - 0.083 13.4 0.0 4.1 7.9 0.1 2.2 2 0 0 2 2 2 0 MORF4 family-associated protein1 GD_N PF16030.5 KIK65782.1 - 0.13 12.5 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Serine protease gd N-terminus RRM_1 PF00076.22 KIK65784.1 - 0.00029 20.6 0.0 0.034 14.0 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GD_N PF16030.5 KIK65784.1 - 0.2 12.0 0.2 0.36 11.2 0.2 1.3 1 0 0 1 1 1 0 Serine protease gd N-terminus zf-rbx1 PF12678.7 KIK65785.1 - 1.8e-24 85.8 13.2 2.6e-24 85.3 13.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK65785.1 - 4.3e-16 58.7 8.9 5.6e-16 58.4 8.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KIK65785.1 - 3.5e-06 27.2 15.4 0.00013 22.2 15.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK65785.1 - 0.00081 19.2 14.4 0.069 13.0 14.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK65785.1 - 0.0011 18.8 12.1 0.025 14.5 12.1 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK65785.1 - 0.15 12.0 10.9 0.45 10.4 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIK65785.1 - 0.31 10.7 14.9 66 3.2 14.9 2.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KIK65785.1 - 0.38 10.8 7.8 1.4 9.0 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KIK65785.1 - 0.45 10.7 9.3 2.9 8.1 9.6 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KIK65785.1 - 0.78 9.5 16.7 55 3.6 16.7 2.5 1 1 0 1 1 1 0 RING-like zinc finger ADH_zinc_N PF00107.26 KIK65786.1 - 0.029 14.4 0.3 0.086 12.8 0.3 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ATP_bind_3 PF01171.20 KIK65787.1 - 2.3e-16 60.1 0.0 4.4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KIK65787.1 - 3.3e-16 58.5 4.5 3.3e-16 58.5 4.5 3.6 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 KIK65787.1 - 0.0095 15.5 1.5 0.0095 15.5 1.5 3.3 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 KIK65787.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF4428 PF14471.6 KIK65787.1 - 1.2 9.1 5.7 0.16 11.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) TF_Zn_Ribbon PF08271.12 KIK65787.1 - 6 6.5 11.4 3.6 7.2 0.2 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding WD40 PF00400.32 KIK65788.1 - 2.5e-20 72.4 11.6 7.3e-05 23.5 3.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK65788.1 - 6.7e-08 32.7 0.0 1.1 9.6 0.0 5.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK65788.1 - 0.00021 21.2 0.1 0.025 14.5 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK65788.1 - 0.0014 17.3 0.1 0.016 13.7 0.1 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain MMS1_N PF10433.9 KIK65788.1 - 0.006 15.3 0.0 2.4 6.7 0.0 2.3 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PTPRCAP PF15713.5 KIK65788.1 - 0.0087 16.4 0.2 0.0087 16.4 0.2 2.5 3 0 0 3 3 3 1 Protein tyrosine phosphatase receptor type C-associated BBS2_N PF14781.6 KIK65788.1 - 0.13 12.1 0.0 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal COesterase PF00135.28 KIK65792.1 - 2.9e-71 240.9 0.0 3.5e-62 210.9 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK65792.1 - 8.8e-07 29.0 0.1 2e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK65793.1 - 7.8e-78 262.6 0.1 1.6e-68 231.8 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK65793.1 - 2.1e-06 27.8 0.0 4.9e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AA_permease_2 PF13520.6 KIK65794.1 - 2.6e-57 194.6 50.5 3.3e-57 194.2 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK65794.1 - 1.2e-15 57.1 44.5 1.8e-15 56.5 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease Mannitol_dh_C PF08125.13 KIK65795.1 - 2.1e-47 161.7 0.0 3.4e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KIK65795.1 - 1.1e-23 84.0 0.1 4.3e-23 82.2 0.0 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain ApbA PF02558.16 KIK65795.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIK65795.1 - 0.062 12.9 0.3 0.21 11.2 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RcsD_ABL PF16359.5 KIK65795.1 - 0.072 13.2 0.2 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 RcsD-ABL domain 3HCDH_N PF02737.18 KIK65795.1 - 0.094 12.6 0.2 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OTCace PF00185.24 KIK65795.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PSP1 PF04468.12 KIK65796.1 - 3.2e-31 107.4 0.7 5.7e-31 106.6 0.7 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Apt1 PF10351.9 KIK65798.1 - 0.11 11.4 4.8 0.13 11.1 4.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM51 PF15345.6 KIK65799.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Phage_Coat_B PF05356.11 KIK65799.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Phage Coat protein B SPATA1_C PF15743.5 KIK65799.1 - 0.014 15.5 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Cnn_1N PF07989.11 KIK65799.1 - 0.053 13.7 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 RapH_N PF18801.1 KIK65799.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal TSC22 PF01166.18 KIK65799.1 - 0.23 11.8 1.5 0.53 10.6 1.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF5127 PF17168.4 KIK65800.1 - 2.6e-63 213.9 1.3 5e-63 212.9 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65800.1 - 1.6e-39 135.3 0.4 5.5e-39 133.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65800.1 - 1.5e-21 77.6 0.4 2.9e-21 76.6 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyoxalase_5 PF14696.6 KIK65800.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Cauli_VI PF01693.16 KIK65803.1 - 0.00089 19.5 0.4 0.003 17.8 0.4 1.8 1 1 0 1 1 1 1 Caulimovirus viroplasmin DUF3242 PF11586.8 KIK65804.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) SeqA_N PF17206.3 KIK65805.1 - 0.77 9.1 4.8 0.18 11.1 0.8 2.0 2 0 0 2 2 2 0 SeqA protein N-terminal domain DUF5127 PF17168.4 KIK65807.1 - 1.4e-67 227.8 1.1 2.2e-67 227.1 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65807.1 - 1.9e-36 125.3 1.6 3.5e-36 124.5 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65807.1 - 1.7e-20 74.1 0.5 4.1e-20 72.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DDE_1 PF03184.19 KIK65808.1 - 1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIK65808.1 - 0.00015 21.8 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KIK65808.1 - 0.00051 19.8 2.6 0.011 15.5 0.0 2.8 3 1 0 3 3 3 2 DDE superfamily endonuclease DUF1622 PF07784.11 KIK65810.1 - 0.026 14.4 0.3 0.091 12.7 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) DPBB_1 PF03330.18 KIK65811.1 - 1.7e-07 31.4 0.1 3.7e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase YABBY PF04690.13 KIK65811.1 - 0.36 11.4 2.2 0.77 10.3 0.0 2.0 2 0 0 2 2 2 0 YABBY protein Ecl1 PF12855.7 KIK65811.1 - 5.3 8.2 40.8 9.6 7.3 40.8 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Thaumatin PF00314.17 KIK65812.1 - 1.2e-69 234.2 7.8 1.3e-69 234.1 7.8 1.0 1 0 0 1 1 1 1 Thaumatin family PCI PF01399.27 KIK65813.1 - 0.00097 19.6 0.3 0.0024 18.4 0.3 1.6 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KIK65813.1 - 0.0015 18.4 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Spidroin_MaSp PF11260.8 KIK65813.1 - 0.031 14.6 0.7 0.063 13.6 0.7 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 RFX_DNA_binding PF02257.15 KIK65813.1 - 0.13 12.9 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain Adaptin_binding PF10199.9 KIK65814.1 - 0.00039 21.0 1.3 0.00047 20.7 1.3 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Adeno_E3_CR2 PF02439.15 KIK65814.1 - 0.17 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5127 PF17168.4 KIK65815.1 - 9.2e-69 231.7 1.0 1.5e-68 231.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65815.1 - 1.2e-41 142.3 0.7 5.3e-41 140.2 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65815.1 - 4.4e-23 82.5 0.3 1.2e-22 81.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Mannitol_dh_C PF08125.13 KIK65816.1 - 1.1e-38 133.2 0.0 2.1e-38 132.2 0.0 1.5 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KIK65816.1 - 3.4e-19 69.5 0.1 1.1e-18 67.8 0.1 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Adeno_E3_CR2 PF02439.15 KIK65818.1 - 0.0072 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Stevor PF17410.2 KIK65818.1 - 0.017 14.7 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 KIK65818.1 - 0.022 14.7 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 KIK65818.1 - 0.022 13.6 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless DUF4448 PF14610.6 KIK65818.1 - 0.039 13.7 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM51 PF15345.6 KIK65818.1 - 0.049 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 KIK65818.1 - 0.1 13.5 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2298 PF10060.9 KIK65818.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) EphA2_TM PF14575.6 KIK65819.1 - 0.057 14.3 0.0 0.11 13.4 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DMPK_coil PF08826.10 KIK65819.1 - 0.16 12.1 1.0 0.25 11.5 1.0 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like Adeno_E3_CR2 PF02439.15 KIK65819.1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1793 PF08760.11 KIK65820.1 - 1e-44 152.9 4.2 1.2e-44 152.7 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KIK65820.1 - 0.00026 20.4 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain XisH PF08814.10 KIK65820.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 XisH protein DUF5127 PF17168.4 KIK65821.1 - 6.2e-55 186.4 3.6 7e-33 114.3 0.3 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65821.1 - 2.6e-36 124.9 0.1 5e-36 124.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF4964 PF16334.5 KIK65821.1 - 0.00014 21.3 0.2 0.00034 20.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DUF1793 PF08760.11 KIK65822.1 - 5.4e-17 62.7 0.3 5.9e-17 62.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Adeno_E3_CR2 PF02439.15 KIK65823.1 - 4.6e-06 26.3 0.1 8.7e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KIK65823.1 - 0.017 14.5 1.9 0.017 14.5 1.9 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KIK65823.1 - 0.025 15.5 0.0 0.082 13.8 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 KIK65823.1 - 0.062 13.6 0.0 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Syndecan PF01034.20 KIK65823.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Nitrate_red_gam PF02665.14 KIK65823.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit LapA_dom PF06305.11 KIK65823.1 - 0.28 11.0 0.3 0.49 10.3 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Plasmodium_Vir PF05795.11 KIK65823.1 - 0.32 10.4 10.9 0.06 12.8 6.7 1.8 1 1 1 2 2 2 0 Plasmodium vivax Vir protein SOG2 PF10428.9 KIK65823.1 - 3 6.9 38.4 1 8.5 22.9 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein FKBP_C PF00254.28 KIK65824.1 - 2.3e-29 101.6 0.0 2.6e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DPBB_1 PF03330.18 KIK65826.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase DUF5127 PF17168.4 KIK65827.1 - 7.1e-68 228.8 3.7 7.1e-68 228.8 3.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65827.1 - 1.7e-46 158.1 0.8 3.7e-46 157.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65827.1 - 6e-42 143.9 0.4 1.4e-41 142.7 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK65827.1 - 5.3e-06 25.9 0.1 2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK65827.1 - 9.9e-05 21.7 0.0 0.00071 18.9 0.0 2.3 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF5127 PF17168.4 KIK65828.1 - 2.5e-63 213.9 0.3 5e-63 212.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIK65828.1 - 1.2e-49 169.0 2.9 2.7e-49 167.8 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIK65828.1 - 3e-44 150.7 0.1 6.7e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) Bac_rhamnosid6H PF17389.2 KIK65828.1 - 2.8e-05 23.5 0.0 9.3e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4964 PF16334.5 KIK65828.1 - 0.0049 16.4 0.3 0.018 14.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) TMEM51 PF15345.6 KIK65828.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Amnionless PF14828.6 KIK65828.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless DMPK_coil PF08826.10 KIK65831.1 - 0.024 14.8 0.4 0.039 14.1 0.4 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF5127 PF17168.4 KIK65832.1 - 8.3e-60 202.4 0.9 1.2e-59 201.8 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65832.1 - 1.6e-37 128.8 0.0 3.7e-37 127.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1152 PF06626.12 KIK65832.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Hva1_TUDOR PF11160.8 KIK65833.1 - 6.3e-13 48.7 6.5 1.4e-12 47.6 6.5 1.5 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain ProQ_C PF17516.2 KIK65833.1 - 0.0082 15.5 0.2 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 ProQ C-terminal domain CSN5_C PF18323.1 KIK65834.1 - 2.2e-28 99.0 4.5 3.9e-28 98.2 4.5 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 KIK65834.1 - 1.4e-27 96.0 1.7 2e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KIK65834.1 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KIK65834.1 - 0.0064 16.6 1.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) DUF1793 PF08760.11 KIK65836.1 - 2.3e-12 47.7 0.0 3.5e-12 47.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 KIK65837.1 - 2.4e-41 142.0 2.1 3.2e-41 141.6 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65837.1 - 1.5e-06 28.0 0.0 3.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) YabA PF06156.13 KIK65838.1 - 0.00064 20.3 2.0 0.0083 16.7 2.0 2.2 1 1 0 1 1 1 1 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 KIK65838.1 - 0.0025 18.0 3.2 0.004 17.4 3.2 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ZapB PF06005.12 KIK65838.1 - 0.0034 17.8 2.4 0.054 14.0 2.4 2.2 1 1 0 1 1 1 1 Cell division protein ZapB FPP PF05911.11 KIK65838.1 - 0.0047 15.2 4.3 0.0061 14.8 4.3 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil GIT_CC PF16559.5 KIK65838.1 - 0.0048 16.7 5.1 1.6 8.7 3.6 2.5 1 1 1 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 KIK65838.1 - 0.0052 15.7 2.5 0.0087 15.0 2.1 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein TSC22 PF01166.18 KIK65838.1 - 0.0052 17.1 0.8 0.27 11.6 0.8 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family SYCE1 PF15233.6 KIK65838.1 - 0.0071 16.4 1.5 0.012 15.7 1.5 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 ATG16 PF08614.11 KIK65838.1 - 0.0088 16.3 6.2 0.013 15.7 6.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.12 KIK65838.1 - 0.013 15.6 1.3 0.04 14.0 0.3 2.2 1 1 0 2 2 2 0 MbeD/MobD like Fez1 PF06818.15 KIK65838.1 - 0.019 15.5 0.1 0.025 15.1 0.1 1.1 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 KIK65838.1 - 0.028 14.5 7.2 0.39 10.8 4.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KIK65838.1 - 0.036 14.4 1.0 0.073 13.3 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Cast PF10174.9 KIK65838.1 - 0.037 12.3 0.2 0.051 11.8 0.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone bZIP_1 PF00170.21 KIK65838.1 - 0.044 13.9 0.2 5 7.3 0.1 2.5 1 1 2 3 3 3 0 bZIP transcription factor Nnf1 PF03980.14 KIK65838.1 - 0.054 13.9 0.5 0.37 11.2 1.6 1.9 2 0 0 2 2 1 0 Nnf1 KASH_CCD PF14662.6 KIK65838.1 - 0.057 13.2 3.8 0.24 11.2 3.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 KIK65838.1 - 0.063 13.4 1.2 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HMMR_N PF15905.5 KIK65838.1 - 0.11 11.9 2.3 0.16 11.4 2.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CorA PF01544.18 KIK65838.1 - 0.11 11.7 4.8 0.26 10.6 4.0 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CDC4_D PF16856.5 KIK65838.1 - 0.14 12.1 1.8 0.33 10.8 1.8 1.6 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain DUF4201 PF13870.6 KIK65838.1 - 0.16 11.7 4.7 0.24 11.1 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF5641 PF18701.1 KIK65838.1 - 0.16 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Mod_r PF07200.13 KIK65838.1 - 0.22 11.6 6.1 0.42 10.7 6.1 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein PI3K_P85_iSH2 PF16454.5 KIK65838.1 - 0.25 10.9 3.0 0.54 9.8 3.0 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 KIK65838.1 - 0.34 10.7 2.9 9.7 6.0 1.5 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 KIK65838.1 - 0.35 10.1 4.0 0.55 9.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 KIK65838.1 - 0.49 10.8 6.0 1.5 9.2 2.2 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HOOK PF05622.12 KIK65838.1 - 0.57 8.3 4.7 0.74 7.9 4.7 1.1 1 0 0 1 1 1 0 HOOK protein Spc24 PF08286.11 KIK65838.1 - 1.4 9.2 6.0 21 5.4 4.5 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FAA_hydro_N_2 PF18288.1 KIK65838.1 - 1.7 9.1 5.3 7.1 7.1 0.5 3.2 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Sec34 PF04136.15 KIK65838.1 - 2.3 8.1 9.2 15 5.5 3.9 2.6 2 1 0 2 2 2 0 Sec34-like family DASH_Dam1 PF08653.10 KIK65838.1 - 3.2 7.6 5.4 4.8 7.1 1.3 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.12 KIK65838.1 - 4 7.5 8.9 19 5.3 8.9 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein UPF0449 PF15136.6 KIK65838.1 - 4.1 7.9 5.5 31 5.1 1.0 3.2 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 SlyX PF04102.12 KIK65838.1 - 7.5 7.2 7.4 16 6.2 3.9 2.3 1 1 1 2 2 2 0 SlyX Retrotrans_gag PF03732.17 KIK65839.1 - 1.1e-06 28.8 1.1 3.3e-06 27.3 0.8 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK65839.1 - 0.0017 18.2 0.1 0.0037 17.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF5541 PF17695.1 KIK65839.1 - 0.087 13.3 0.1 0.73 10.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5541) Stn1_C PF12659.7 KIK65839.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH AbiJ_NTD4 PF18863.1 KIK65840.1 - 0.0032 17.9 0.0 0.0044 17.5 0.0 1.2 1 0 0 1 1 1 1 AbiJ N-terminal domain 4 CSN5_C PF18323.1 KIK65840.1 - 0.007 17.3 0.1 0.01 16.7 0.1 1.2 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Orthopox_A5L PF06193.11 KIK65840.1 - 0.041 13.3 0.2 0.055 12.9 0.2 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF3752 PF12572.8 KIK65841.1 - 5.2e-39 134.2 8.0 5.2e-39 134.2 8.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DPBB_1 PF03330.18 KIK65842.1 - 5.6e-10 39.4 0.2 9.2e-10 38.7 0.2 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIK65842.1 - 0.027 14.3 0.2 0.037 13.9 0.2 1.2 1 0 0 1 1 1 0 Barwin family DUF5357 PF17310.2 KIK65845.1 - 0.2 10.2 2.2 0.23 10.0 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5357) DUF2157 PF09925.9 KIK65845.1 - 8.2 6.2 12.6 10 5.9 6.8 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) His_Phos_2 PF00328.22 KIK65846.1 - 1.3e-47 162.9 0.0 1.8e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4418 PF14387.6 KIK65847.1 - 0.082 13.1 2.7 0.22 11.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Chs7 PF12271.8 KIK65848.1 - 5.7e-21 75.1 5.9 6e-21 75.0 5.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Wzy_C_2 PF11846.8 KIK65849.1 - 0.032 14.1 1.9 1.5 8.7 0.1 2.5 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF1129 PF06570.11 KIK65849.1 - 7.6 6.0 15.5 4.2 6.8 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Chs7 PF12271.8 KIK65851.1 - 1.6e-113 378.9 24.1 1.8e-113 378.7 24.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone PP2C PF00481.21 KIK65852.1 - 0.00022 20.9 0.0 0.0004 20.1 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C p450 PF00067.22 KIK65853.1 - 5.4e-57 193.6 0.0 7.3e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4965 PF16335.5 KIK65854.1 - 1.9e-07 30.9 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65855.1 - 2.3e-35 122.5 0.0 2.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) RTBV_P12 PF06361.11 KIK65855.1 - 0.12 12.8 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Phage_holin_2_4 PF16082.5 KIK65856.1 - 0.025 14.3 0.5 0.079 12.7 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like FixQ PF05545.11 KIK65856.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Retrotran_gag_2 PF14223.6 KIK65857.1 - 1.9e-14 53.5 0.0 2.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MBOAT_2 PF13813.6 KIK65858.1 - 0.0073 16.6 0.8 0.017 15.3 0.1 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F_bP_aldolase PF01116.20 KIK65858.1 - 0.14 11.6 0.0 2.6 7.5 0.0 2.0 1 1 1 2 2 2 0 Fructose-bisphosphate aldolase class-II Leader_Thr PF08254.11 KIK65858.1 - 8 6.3 6.9 27 4.6 0.5 2.6 2 0 0 2 2 2 0 Threonine leader peptide ANAPC4_WD40 PF12894.7 KIK65860.1 - 7.3e-08 32.6 0.0 0.56 10.5 0.0 5.3 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK65860.1 - 8.7e-08 32.7 1.5 0.42 11.6 0.0 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat MPP6 PF10175.9 KIK65860.1 - 0.036 14.6 2.0 0.09 13.3 2.0 1.7 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Hira PF07569.11 KIK65860.1 - 0.036 13.8 0.0 0.18 11.5 0.0 2.2 3 0 0 3 3 3 0 TUP1-like enhancer of split SPO22 PF08631.10 KIK65861.1 - 1e-67 228.6 17.4 9.3e-66 222.1 2.9 3.8 3 1 1 4 4 4 3 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KIK65861.1 - 0.00013 22.1 3.4 0.61 10.4 0.1 5.7 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK65861.1 - 0.00042 20.2 5.1 16 5.9 0.6 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK65861.1 - 0.0041 17.6 0.2 0.38 11.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK65861.1 - 0.026 14.7 3.2 1.9 8.8 0.5 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 LOH1CR12 PF10158.9 KIK65861.1 - 0.039 14.0 0.4 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Tumour suppressor protein Cyclin PF08613.11 KIK65863.1 - 1.4e-13 51.6 0.1 3.9e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIK65863.1 - 4.2e-07 29.8 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Trp_oprn_chp PF09534.10 KIK65866.1 - 0.15 11.9 0.3 0.63 9.8 0.3 2.2 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 KIK65867.1 - 6 6.5 8.6 1.8 8.2 0.5 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF5127 PF17168.4 KIK65872.1 - 1.4e-66 224.6 0.6 2.7e-66 223.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65872.1 - 5.1e-46 156.5 0.2 1.1e-45 155.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65872.1 - 1.8e-40 139.1 2.2 3.9e-40 138.0 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK65872.1 - 6.1e-07 28.9 0.1 1.6e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 KIK65872.1 - 0.00023 20.5 0.1 0.00067 19.0 0.1 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain ArsP_1 PF03773.13 KIK65875.1 - 0.16 11.1 8.2 0.55 9.3 8.2 1.7 1 1 0 1 1 1 0 Predicted permease Pkinase_Tyr PF07714.17 KIK65876.1 - 7.2e-21 74.6 0.0 9.1e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65876.1 - 1e-14 54.6 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65877.1 - 1e-12 47.9 0.0 1.3e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65877.1 - 8.8e-10 38.4 0.0 1e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PAP_central PF04928.17 KIK65878.1 - 3.7e-101 337.3 0.0 5.6e-101 336.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KIK65878.1 - 2.5e-48 163.9 0.0 3.7e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KIK65878.1 - 1.8e-10 41.0 0.0 4.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIK65878.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 KIK65878.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DNA_pol_B_palm PF14792.6 KIK65878.1 - 0.095 12.9 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase beta palm rve PF00665.26 KIK65879.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Pox_A21 PF05323.12 KIK65882.1 - 0.028 15.0 0.0 0.041 14.5 0.0 1.3 1 1 0 1 1 1 0 Poxvirus A21 Protein DUF5127 PF17168.4 KIK65884.1 - 2.7e-51 174.5 0.5 3.4e-51 174.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Hpre_diP_synt_I PF07456.11 KIK65885.1 - 0.049 13.6 15.1 0.063 13.3 9.7 2.3 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I TMEM100 PF16311.5 KIK65885.1 - 0.052 13.1 2.1 0.096 12.3 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Mad3_BUB1_I_2 PF17014.5 KIK65885.1 - 0.81 9.8 4.1 6 7.0 0.1 2.5 2 1 1 3 3 3 0 Putative Mad3/BUB1 like region 1 protein DUF5127 PF17168.4 KIK65886.1 - 4.2e-64 216.5 1.7 6.4e-64 215.8 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65886.1 - 2e-44 151.3 0.3 7.9e-44 149.3 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4965) Bac_rhamnosid6H PF17389.2 KIK65886.1 - 0.061 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain ArsP_1 PF03773.13 KIK65887.1 - 0.093 11.9 7.8 0.2 10.8 7.8 1.5 1 1 0 1 1 1 0 Predicted permease G-alpha PF00503.20 KIK65888.1 - 1.4e-100 336.9 0.0 1.7e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK65888.1 - 9e-13 48.0 1.0 2.4e-08 33.6 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK65888.1 - 0.0041 17.2 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK65888.1 - 0.0041 16.5 3.0 0.71 9.2 1.1 2.8 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK65888.1 - 0.0094 16.2 0.3 1.4 9.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK65888.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK65888.1 - 0.14 12.1 0.1 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DPBB_1 PF03330.18 KIK65889.1 - 7.2e-09 35.8 0.3 1.1e-08 35.2 0.3 1.5 1 1 0 1 1 1 1 Lytic transglycolase DUF5127 PF17168.4 KIK65890.1 - 7.6e-51 173.1 1.6 1.2e-39 136.4 0.2 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KIK65890.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) DUF1793 PF08760.11 KIK65891.1 - 1.6e-31 110.0 1.1 2.1e-31 109.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) F-box_4 PF15966.5 KIK65891.1 - 0.064 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 F-box DUF5127 PF17168.4 KIK65892.1 - 6.4e-68 228.9 0.6 9.3e-68 228.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK65892.1 - 1.9e-38 131.8 0.1 4.1e-38 130.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK65892.1 - 2.4e-21 76.9 0.0 4.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF1793 PF08760.11 KIK65893.1 - 5.2e-16 59.5 0.1 5.7e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Rgp1 PF08737.10 KIK65894.1 - 2.6e-43 148.8 0.2 3.7e-20 72.5 0.0 3.4 3 0 0 3 3 3 2 Rgp1 Arrestin_C PF02752.22 KIK65894.1 - 0.002 18.6 0.0 7.8 7.0 0.0 3.5 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain OPT PF03169.15 KIK65895.1 - 4.1e-179 597.2 53.5 4.7e-179 597.0 53.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BRI3BP PF14965.6 KIK65896.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 CbiQ PF02361.16 KIK65896.1 - 0.067 12.8 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Cobalt transport protein LapA_dom PF06305.11 KIK65896.1 - 0.1 12.4 4.4 0.26 11.1 0.0 2.4 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3040 PF11239.8 KIK65896.1 - 1.2 9.4 5.6 1.1 9.6 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Glyco_hydro_71 PF03659.14 KIK65897.1 - 7.7e-116 387.0 3.5 9.2e-116 386.7 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 MnhB PF04039.13 KIK65899.1 - 0.95 9.8 10.9 0.16 12.3 0.3 2.7 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter AA_permease_2 PF13520.6 KIK65900.1 - 6.4e-58 196.6 57.8 7.7e-58 196.3 57.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK65900.1 - 6.8e-14 51.3 50.4 1.2e-13 50.5 50.4 1.3 1 1 0 1 1 1 1 Amino acid permease ATG27 PF09451.10 KIK65900.1 - 5.3 6.8 4.3 23 4.8 0.9 2.6 2 0 0 2 2 2 0 Autophagy-related protein 27 Ion_trans_2 PF07885.16 KIK65901.1 - 1e-25 89.5 21.5 5.6e-17 61.5 7.1 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KIK65901.1 - 1.8e-05 24.1 2.8 4.3e-05 22.9 2.8 1.5 1 0 0 1 1 1 1 Ion transport protein DUF2070 PF09843.9 KIK65901.1 - 0.98 7.6 12.4 0.77 8.0 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) 7tm_3 PF00003.22 KIK65901.1 - 1.4 8.6 10.3 0.28 10.9 0.3 2.8 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Allexi_40kDa PF05549.11 KIK65902.1 - 0.19 11.2 2.4 0.25 10.8 2.4 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein ADIP PF11559.8 KIK65902.1 - 1.2 9.2 16.6 0.065 13.3 7.4 2.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 KIK65902.1 - 3.6 8.2 16.1 4.8 7.9 0.9 2.5 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med21 PF11221.8 KIK65902.1 - 5.9 7.1 14.0 1.3 9.3 10.4 1.8 2 1 0 2 2 2 0 Subunit 21 of Mediator complex TPMT PF05724.11 KIK65903.1 - 5.7e-19 68.6 0.0 4e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KIK65903.1 - 3.1e-06 27.8 0.0 8.2e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK65903.1 - 0.00015 21.6 0.0 0.00058 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK65903.1 - 0.00064 20.3 0.0 0.0025 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK65903.1 - 0.0063 17.2 0.0 0.021 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK65903.1 - 0.055 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIK65903.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KIK65903.1 - 0.13 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KIK65904.1 - 5.8e-32 111.1 0.0 6.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KIK65904.1 - 1.2e-08 35.6 0.0 2e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK65904.1 - 6.2e-06 26.8 0.0 0.0001 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK65904.1 - 3e-05 23.8 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIK65904.1 - 7.5e-05 23.4 0.0 0.0031 18.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK65904.1 - 0.0093 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Oxidored_FMN PF00724.20 KIK65905.1 - 3.9e-61 207.2 0.0 5e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIK65905.1 - 0.0023 17.6 0.8 0.0048 16.6 0.1 1.8 2 0 0 2 2 2 1 Repeat of unknown function (DUF346) RabGAP-TBC PF00566.18 KIK65910.1 - 1.6e-48 165.2 0.0 2.6e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spc7 PF08317.11 KIK65910.1 - 0.13 11.1 3.3 0.22 10.4 3.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KIK65911.1 - 0.011 15.8 4.8 0.018 15.1 4.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AI-2E_transport PF01594.16 KIK65911.1 - 0.24 10.5 0.3 0.32 10.1 0.3 1.1 1 0 0 1 1 1 0 AI-2E family transporter HSBP1 PF06825.12 KIK65911.1 - 0.27 11.1 1.3 1.1 9.1 0.1 2.6 2 1 1 3 3 3 0 Heat shock factor binding protein 1 T2SSI PF02501.17 KIK65913.1 - 0.05 13.8 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Alpha-amylase PF00128.24 KIK65914.1 - 3.1e-58 197.9 2.8 4.1e-58 197.5 2.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIK65914.1 - 3.4e-16 59.3 0.2 7e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KIK65915.1 - 1.9e-55 188.8 1.6 3.3e-28 99.2 0.0 2.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIK65915.1 - 3.7e-15 56.0 0.3 8e-15 54.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) TrbC PF04956.13 KIK65917.1 - 0.014 15.6 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family KdgT PF03812.13 KIK65917.1 - 0.033 13.5 1.3 0.046 13.0 1.3 1.1 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease DUF202 PF02656.15 KIK65917.1 - 0.87 10.1 3.6 1.6 9.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) zf-NOSIP PF15906.5 KIK65919.1 - 6.5e-11 42.2 0.5 1.7e-10 40.9 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 KIK65919.1 - 1.7e-08 34.2 17.0 1.5e-05 24.8 7.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK65919.1 - 3e-06 27.0 19.7 0.0017 18.1 9.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK65919.1 - 3e-05 23.9 15.0 0.0015 18.5 1.1 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KIK65919.1 - 3.5e-05 24.0 17.2 0.012 15.9 8.6 2.6 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KIK65919.1 - 4.1e-05 23.5 19.8 9.7e-05 22.3 7.9 2.9 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK65919.1 - 9.1e-05 22.2 20.5 0.019 14.8 2.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK65919.1 - 0.043 13.7 20.4 1.6 8.6 10.0 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK65919.1 - 0.074 13.2 15.3 0.085 13.0 1.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 KIK65919.1 - 0.1 12.6 12.7 0.084 12.9 4.4 2.4 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 KIK65919.1 - 2.2 8.4 15.5 1.4 9.0 1.1 3.3 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_10 PF16685.5 KIK65919.1 - 3.6 7.8 13.9 7.5 6.8 6.5 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 KIK65919.1 - 3.8 7.5 11.0 0.37 10.7 5.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S27e PF01667.17 KIK65919.1 - 4.2 7.1 8.6 0.4 10.4 3.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 SPC25 PF06703.11 KIK65920.1 - 0.026 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Herpes_pp38 PF04846.13 KIK65920.1 - 0.11 12.5 1.6 0.17 11.8 1.6 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF443 PF04276.12 KIK65920.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF443) SIT PF15330.6 KIK65920.1 - 0.5 10.8 2.7 1.9 9.0 0.0 2.6 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Med4 PF10018.9 KIK65927.1 - 0.091 12.4 1.0 0.16 11.6 1.0 1.6 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 LMBR1 PF04791.16 KIK65927.1 - 0.17 10.8 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Med21 PF11221.8 KIK65928.1 - 0.0074 16.6 0.0 0.0074 16.6 0.0 2.2 2 1 0 2 2 2 1 Subunit 21 of Mediator complex YscO PF07321.12 KIK65928.1 - 0.034 14.1 0.7 0.051 13.5 0.7 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO LMBR1 PF04791.16 KIK65928.1 - 0.045 12.7 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 KIK65928.1 - 0.053 13.5 0.4 0.082 12.9 0.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SseC PF04888.12 KIK65928.1 - 1.3 8.5 7.3 0.65 9.5 0.1 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family adh_short PF00106.25 KIK65931.1 - 1.7e-39 135.3 0.0 2.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK65931.1 - 3.1e-28 98.9 0.0 4.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIK65931.1 - 1.2e-07 31.4 0.0 2.1e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK65931.1 - 0.00035 20.1 0.1 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIK65931.1 - 0.00085 19.3 0.2 0.0075 16.2 0.0 2.4 2 1 0 2 2 2 1 KR domain DUF3040 PF11239.8 KIK65932.1 - 0.014 15.7 0.2 0.02 15.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MerC PF03203.14 KIK65932.1 - 0.049 14.1 0.1 0.074 13.5 0.1 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein DUF4231 PF14015.6 KIK65932.1 - 0.08 13.4 0.2 0.57 10.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SLATT_fungal PF18142.1 KIK65932.1 - 0.18 11.8 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain SPC12 PF06645.13 KIK65932.1 - 0.2 11.8 0.8 0.34 11.0 0.8 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TPMT PF05724.11 KIK65933.1 - 3.8e-38 131.4 0.0 4.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KIK65933.1 - 3.1e-13 50.2 0.0 4.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK65933.1 - 1.2e-10 41.4 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK65933.1 - 1.2e-09 38.7 0.0 1.7e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK65933.1 - 7.9e-07 29.7 0.0 1.2e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK65933.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIK65933.1 - 0.0011 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KIK65933.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KIK65933.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KIK65933.1 - 0.22 10.8 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribonuclease PF00545.20 KIK65934.1 - 0.00038 21.1 0.0 0.00047 20.8 0.0 1.2 1 0 0 1 1 1 1 ribonuclease PP2C PF00481.21 KIK65936.1 - 4.3e-24 85.5 0.0 4.3e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK65936.1 - 0.00048 19.8 0.0 0.0016 18.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 KIK65938.1 - 2.1e-36 125.7 0.0 4.7e-36 124.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65938.1 - 1.2e-35 123.1 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK65938.1 - 0.0043 17.0 1.1 0.031 14.2 1.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KIK65938.1 - 0.15 11.2 0.0 0.68 9.1 0.0 1.9 2 1 0 2 2 2 0 Fructosamine kinase RIO1 PF01163.22 KIK65938.1 - 0.18 11.4 0.1 0.4 10.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK65940.1 - 1.9e-14 53.6 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65940.1 - 2.3e-11 43.6 0.0 9.5e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Terpene_synth_C PF03936.16 KIK65941.1 - 2.8e-05 23.6 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.16 KIK65943.1 - 2.3e-05 23.9 0.1 3.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIK65943.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) DUF4597 PF15366.6 KIK65944.1 - 0.0038 16.9 2.0 0.027 14.2 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4597) CRAL_TRIO PF00650.20 KIK65946.1 - 1.2e-26 93.3 0.0 1.6e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK65946.1 - 0.00016 21.8 1.3 0.00049 20.2 1.3 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF4491 PF14898.6 KIK65946.1 - 0.041 14.3 0.1 0.099 13.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) TFIIF_beta PF02270.15 KIK65946.1 - 0.041 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain CRAL_TRIO_2 PF13716.6 KIK65946.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK65947.1 - 2.7e-24 85.7 0.0 3.6e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK65947.1 - 0.00085 19.5 1.1 0.003 17.7 1.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TFIIF_beta PF02270.15 KIK65947.1 - 0.025 14.7 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain SAP PF02037.27 KIK65948.1 - 0.0006 19.5 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 SAP domain DUF742 PF05331.11 KIK65948.1 - 0.017 14.9 2.1 0.025 14.4 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF742) Cwf_Cwc_15 PF04889.12 KIK65948.1 - 0.12 12.1 6.8 0.031 14.0 2.1 2.1 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CRAL_TRIO PF00650.20 KIK65949.1 - 3.3e-24 85.4 0.0 4.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK65949.1 - 4.8e-06 26.7 0.2 1.6e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Nucleocap_ssRNA PF11128.8 KIK65949.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid CRAL_TRIO PF00650.20 KIK65950.1 - 3.7e-25 88.5 0.0 5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK65950.1 - 3.9e-06 27.0 0.3 3.9e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF3654 PF12376.8 KIK65950.1 - 0.17 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) COesterase PF00135.28 KIK65951.1 - 1.8e-82 277.8 1.1 6.2e-72 243.1 0.9 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK65951.1 - 2.4e-07 30.8 0.0 1.3e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 KIK65951.1 - 0.091 12.7 0.9 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 Cutinase COesterase PF00135.28 KIK65952.1 - 6e-06 25.4 0.0 6.2e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pro_dh PF01619.18 KIK65953.1 - 4.5e-52 177.4 0.0 1.8e-50 172.2 0.0 2.3 1 1 0 1 1 1 1 Proline dehydrogenase Pkinase PF00069.25 KIK65954.1 - 1.6e-36 126.1 0.0 2.6e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65954.1 - 8.8e-35 120.2 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK65954.1 - 0.0071 16.3 0.7 0.06 13.3 0.7 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK65954.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Fructosamin_kin PF03881.14 KIK65954.1 - 0.18 10.9 0.0 0.39 9.9 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase BCIP PF13862.6 KIK65956.1 - 3e-65 219.9 0.2 3.5e-65 219.6 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein TIP120 PF08623.10 KIK65957.1 - 9.2e-58 194.7 0.9 2e-55 187.1 0.0 3.7 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KIK65957.1 - 7.6e-15 55.1 11.6 0.0027 18.1 0.5 8.2 6 2 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 KIK65957.1 - 8.7e-13 48.5 20.7 0.031 14.8 0.0 11.4 11 2 2 13 13 13 3 HEAT-like repeat HEAT PF02985.22 KIK65957.1 - 5.3e-12 44.9 18.7 0.13 12.6 0.1 12.0 13 0 0 13 13 11 3 HEAT repeat CLASP_N PF12348.8 KIK65957.1 - 3.6e-08 33.3 3.5 0.0082 15.7 0.1 5.9 5 1 1 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 KIK65957.1 - 1.6e-07 30.3 7.2 0.077 11.5 0.0 5.8 4 2 2 6 6 6 4 Adaptin N terminal region Cnd1 PF12717.7 KIK65957.1 - 1.9e-07 31.3 8.7 0.12 12.4 0.1 6.6 5 2 3 9 9 8 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KIK65957.1 - 1.1e-06 28.7 0.4 0.0011 18.9 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Telomere_reg-2 PF10193.9 KIK65957.1 - 2.1e-05 24.9 1.7 0.15 12.5 0.0 4.1 3 0 0 3 3 3 1 Telomere length regulation protein RTP1_C1 PF10363.9 KIK65957.1 - 7.1e-05 23.0 4.2 0.054 13.7 0.1 5.2 4 2 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KIK65957.1 - 8.4e-05 23.1 1.1 3.3 8.4 0.1 6.0 7 1 0 7 7 6 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 KIK65957.1 - 0.00011 21.9 7.1 0.56 9.7 0.0 5.3 6 0 0 6 6 6 2 Tti2 family MMS19_C PF12460.8 KIK65957.1 - 0.0042 16.3 0.2 0.0042 16.3 0.2 5.7 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal V-ATPase_H_C PF11698.8 KIK65957.1 - 0.0061 16.7 1.1 0.43 10.7 0.4 4.1 4 1 1 5 5 5 1 V-ATPase subunit H TAF6_C PF07571.13 KIK65957.1 - 0.043 14.2 0.1 15 6.0 0.0 4.1 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain DUF3384 PF11864.8 KIK65957.1 - 0.052 12.4 0.2 0.63 8.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3384) Sec5 PF15469.6 KIK65957.1 - 0.12 12.2 0.5 0.28 11.0 0.5 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 MMS19_N PF14500.6 KIK65957.1 - 0.37 10.3 2.9 99 2.4 0.1 5.2 5 3 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.7 KIK65957.1 - 6 7.3 6.2 26 5.2 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion MutS_V PF00488.21 KIK65958.1 - 2.7e-58 197.1 0.0 6e-58 196.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK65958.1 - 5e-31 108.4 3.5 5e-31 108.4 3.5 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KIK65958.1 - 2.7e-07 30.8 0.5 7.3e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KIK65958.1 - 6.7e-07 29.7 0.0 4.6e-06 27.0 0.0 2.5 1 1 0 1 1 1 1 MutS domain II Peptidase_C13 PF01650.18 KIK65959.1 - 4.3e-05 23.1 0.0 7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KIK65959.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Caspase domain RNA_pol_Rpb1_5 PF04998.17 KIK65961.1 - 9.4e-105 349.8 0.0 1.3e-104 349.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIK65961.1 - 8.8e-74 247.2 0.0 1.6e-73 246.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KIK65961.1 - 1.6e-66 223.8 0.0 2.9e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_1 PF04997.12 KIK65961.1 - 1.7e-58 198.4 0.0 2.5e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KIK65961.1 - 1.2e-51 174.8 0.0 2.6e-50 170.4 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KIK65961.1 - 3.7e-50 169.4 0.4 7.4e-50 168.4 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KIK65961.1 - 1.3e-36 124.8 0.0 2.9e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KIK65961.1 - 5.7e-13 48.5 189.3 0.0083 16.4 5.4 13.9 7 3 8 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat VHS PF00790.19 KIK65962.1 - 8.9e-42 142.3 0.3 2.2e-41 141.0 0.0 1.8 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KIK65962.1 - 1.3e-16 60.5 6.5 2.3e-16 59.7 6.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KIK65962.1 - 2.8e-07 30.0 8.4 0.0011 18.7 2.8 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KIK65962.1 - 0.00036 20.8 0.4 0.0012 19.1 0.1 2.0 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 KIK65962.1 - 0.0036 17.5 3.9 0.008 16.4 3.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger HEAT_2 PF13646.6 KIK65962.1 - 0.17 12.3 0.6 0.72 10.3 0.1 2.3 2 1 0 2 2 2 0 HEAT repeats C1_1 PF00130.22 KIK65962.1 - 1.4 8.8 6.4 0.15 11.9 1.9 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KIK65962.1 - 2.4 8.2 9.3 2.5 8.2 4.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF2975 PF11188.8 KIK65964.1 - 1.3 8.9 13.4 0.9 9.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) NapE PF06796.11 KIK65965.1 - 0.88 9.1 8.8 11 5.7 3.1 2.9 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE AC_N PF16214.5 KIK65966.1 - 0.19 10.8 0.3 0.3 10.2 0.3 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Cytochrom_C PF00034.21 KIK65967.1 - 4.2e-10 40.6 0.0 5.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KIK65967.1 - 1.7e-07 31.5 0.8 9.3e-07 29.1 0.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KIK65967.1 - 0.00077 19.2 1.4 0.011 15.5 1.5 2.5 1 1 0 1 1 1 1 Cytochrome c-550 domain Amidohydro_2 PF04909.14 KIK65968.1 - 2.7e-22 79.9 0.0 8.1e-22 78.3 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase HTH_20 PF12840.7 KIK65968.1 - 0.052 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2070 PF09843.9 KIK65969.1 - 9.3 4.4 14.2 0.33 9.2 7.8 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 KIK65970.1 - 0.0074 15.3 5.7 0.0098 14.8 5.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 KIK65971.1 - 7.7e-34 117.1 0.0 9.3e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65971.1 - 1e-29 103.7 0.0 1.2e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK65971.1 - 0.0003 19.7 0.1 0.00038 19.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK65971.1 - 0.00054 19.6 0.1 0.00066 19.3 0.1 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK65971.1 - 0.074 13.0 0.3 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1027 PF06265.11 KIK65972.1 - 0.02 14.9 0.2 1.2 9.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1027) FAM92 PF06730.11 KIK65972.1 - 0.038 13.4 0.4 0.068 12.6 0.4 1.5 1 1 1 2 2 2 0 FAM92 protein Pkinase PF00069.25 KIK65975.1 - 2.1e-07 30.6 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65975.1 - 1.2e-05 24.7 0.0 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK65976.1 - 2.1e-26 92.9 0.0 3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65976.1 - 4.8e-25 88.3 0.0 7.1e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65976.1 - 0.00036 19.9 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK65976.1 - 0.0043 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK65976.1 - 0.038 12.8 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 KIK65977.1 - 6.1e-49 164.5 22.7 1.5e-10 41.5 0.1 6.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK65977.1 - 1.9e-41 139.9 7.7 5.5e-07 30.0 0.1 8.6 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK65977.1 - 1.1e-32 108.4 14.2 0.00019 21.6 0.0 11.0 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 KIK65977.1 - 8.8e-32 108.2 18.9 0.00066 20.0 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KIK65977.1 - 2.9e-29 100.8 15.3 2.9e-06 27.4 0.1 7.0 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Med9 PF07544.13 KIK65978.1 - 7.7e-06 25.9 0.1 1e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 COesterase PF00135.28 KIK65979.1 - 9.6e-88 295.3 0.0 1.6e-87 294.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK65979.1 - 1.1e-08 35.2 0.2 3.6e-08 33.5 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK65979.1 - 0.12 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KIK65980.1 - 3.7e-90 303.2 0.0 5.5e-90 302.7 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK65980.1 - 1.5e-09 38.1 0.4 6.5e-09 35.9 0.3 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK65980.1 - 0.042 13.3 0.1 0.064 12.7 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_2 PF12796.7 KIK65981.1 - 2.1e-87 287.8 24.1 1.5e-17 63.9 0.4 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK65981.1 - 1.7e-58 194.2 11.8 3e-10 40.4 0.4 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KIK65981.1 - 9e-47 155.6 14.7 7.1e-06 26.2 0.3 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 KIK65981.1 - 1.9e-46 150.6 5.6 0.00012 22.2 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KIK65981.1 - 1.1e-45 153.1 4.6 1.7e-09 37.7 0.0 6.9 2 2 5 7 7 7 7 Ankyrin repeats (many copies) DpaA_N PF16924.5 KIK65981.1 - 0.035 14.2 0.0 39 4.4 0.0 4.3 4 1 2 6 6 6 0 Dipicolinate synthase subunit A N-terminal domain Ank_4 PF13637.6 KIK65982.1 - 2.6e-36 123.5 1.1 4.7e-12 46.2 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KIK65982.1 - 9.1e-28 95.5 1.0 2e-07 31.1 0.1 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KIK65982.1 - 5.6e-26 90.9 0.0 2.4e-14 53.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK65982.1 - 7.1e-24 81.3 0.3 1.2e-05 25.3 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KIK65982.1 - 4.9e-21 74.5 0.0 1.3e-05 25.4 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) ERbeta_N PF12497.8 KIK65983.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Estrogen receptor beta AAA_29 PF13555.6 KIK65983.1 - 0.12 12.2 0.5 0.23 11.3 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pkinase PF00069.25 KIK65984.1 - 4.2e-26 91.9 0.0 5.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65984.1 - 9.3e-10 38.2 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65984.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK65984.1 - 0.028 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK65984.1 - 0.19 11.6 0.2 0.32 10.9 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SGTA_dimer PF16546.5 KIK65986.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Homodimerisation domain of SGTA Pheromone PF08015.11 KIK65993.1 - 0.00015 22.8 1.8 0.00018 22.5 1.8 1.1 1 0 0 1 1 1 1 Fungal mating-type pheromone DUF5082 PF16888.5 KIK65994.1 - 0.00068 19.9 11.3 0.0014 18.9 9.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) AAA_13 PF13166.6 KIK65994.1 - 0.017 13.8 15.4 0.025 13.2 15.4 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 KIK65994.1 - 0.027 12.4 1.2 0.04 11.9 1.2 1.1 1 0 0 1 1 1 0 Prominin BRE1 PF08647.11 KIK65994.1 - 0.085 12.9 5.8 0.075 13.1 2.4 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FAM184 PF15665.5 KIK65994.1 - 0.097 12.4 9.6 0.18 11.5 9.6 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TPR_2 PF07719.17 KIK65994.1 - 0.099 12.8 0.1 0.45 10.8 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 KIK65994.1 - 0.14 12.2 8.7 0.31 11.1 3.4 3.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KIK65994.1 - 0.16 9.4 16.9 0.27 8.7 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.6 KIK65994.1 - 0.17 11.3 6.8 0.32 10.4 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SHNi-TPR PF10516.9 KIK65994.1 - 0.18 11.3 0.1 0.57 9.7 0.1 1.8 1 0 0 1 1 1 0 SHNi-TPR Syntaxin_2 PF14523.6 KIK65994.1 - 0.21 12.0 3.0 0.42 11.0 3.0 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Lebercilin PF15619.6 KIK65994.1 - 0.3 10.7 6.8 0.16 11.6 4.4 1.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Hemagglutinin PF00509.18 KIK65994.1 - 0.34 9.3 2.7 0.55 8.6 2.7 1.2 1 0 0 1 1 1 0 Haemagglutinin Syntaxin-6_N PF09177.11 KIK65994.1 - 0.35 11.4 8.6 0.15 12.6 3.2 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1351 PF07083.11 KIK65994.1 - 0.47 10.2 7.0 1.1 9.0 7.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) DASH_Duo1 PF08651.10 KIK65994.1 - 0.47 10.3 1.6 7.8 6.3 0.1 3.0 3 0 0 3 3 2 0 DASH complex subunit Duo1 TolA_bind_tri PF16331.5 KIK65994.1 - 0.72 10.0 5.0 1.6 8.8 0.7 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation GBP_C PF02841.14 KIK65994.1 - 0.97 8.8 7.1 1.6 8.1 7.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spc7 PF08317.11 KIK65994.1 - 1.2 7.9 8.6 2.1 7.1 8.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.21 KIK65994.1 - 1.2 8.6 14.9 1.5 8.3 7.3 2.2 1 1 1 2 2 2 0 Intermediate filament protein SH3BP5 PF05276.14 KIK65994.1 - 1.9 8.3 10.0 18 5.0 10.0 2.2 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) TPR_MLP1_2 PF07926.12 KIK65994.1 - 2.1 8.4 16.2 7.4 6.6 12.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KIK65994.1 - 2.3 6.3 10.4 15 3.6 10.4 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 KIK65994.1 - 3.2 8.0 8.6 2 8.6 6.2 1.9 1 1 0 2 2 1 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 KIK65994.1 - 3.7 7.6 8.3 22 5.0 5.5 2.7 1 1 1 2 2 2 0 Laminin Domain II IMD PF08397.11 KIK65994.1 - 3.9 6.8 5.9 8.2 5.7 5.9 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain GAS PF13851.6 KIK65994.1 - 5.1 6.4 8.8 9.7 5.5 7.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KIK65994.1 - 7.6 6.6 9.8 2.7 8.0 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L19e PF01280.20 KIK65995.1 - 2.3e-61 206.1 10.3 2.3e-61 206.1 10.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 KIK65995.1 - 0.0052 16.5 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 S4 domain FAF PF11250.8 KIK65995.1 - 0.18 12.1 1.3 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 Fantastic Four meristem regulator DUF349 PF03993.12 KIK65995.1 - 0.96 9.8 7.2 2.3 8.6 3.1 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Pkinase PF00069.25 KIK65996.1 - 1.6e-57 194.9 0.0 2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK65996.1 - 7.5e-26 91.0 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK65996.1 - 4e-05 23.1 0.5 0.00021 20.7 0.1 2.3 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK65996.1 - 0.015 14.9 0.0 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 p450 PF00067.22 KIK65998.1 - 9.4e-39 133.4 0.1 7.8e-38 130.4 0.1 2.2 1 1 1 2 2 2 1 Cytochrome P450 PTS_IIB PF02302.17 KIK65998.1 - 0.19 12.5 0.0 0.32 11.7 0.0 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit p450 PF00067.22 KIK65999.1 - 1.1e-62 212.3 0.0 1.4e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 KIK66000.1 - 2.6e-42 144.3 0.0 4.2e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KIK66000.1 - 1.4e-23 82.7 0.6 4e-23 81.2 0.6 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KIK66000.1 - 1.2e-21 76.5 4.9 2.2e-21 75.7 4.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.6 KIK66000.1 - 2.5e-06 27.8 0.2 0.00097 19.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KIK66000.1 - 4.2e-06 26.5 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK66000.1 - 5e-06 27.0 0.2 0.00016 22.1 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIK66000.1 - 7.9e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KIK66000.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KIK66000.1 - 5.3e-05 23.2 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KIK66000.1 - 5.9e-05 23.1 0.4 0.00024 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KIK66000.1 - 0.00058 19.2 0.1 0.0019 17.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KIK66000.1 - 0.0013 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIK66000.1 - 0.0013 18.0 0.0 0.0031 16.7 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIK66000.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK66000.1 - 0.0015 19.0 0.1 0.0046 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KIK66000.1 - 0.0017 18.8 0.0 0.0068 16.8 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_2 PF07724.14 KIK66000.1 - 0.0022 18.2 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KIK66000.1 - 0.0061 16.2 0.1 0.7 9.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KIK66000.1 - 0.013 14.9 0.1 3.5 6.9 0.0 2.4 1 1 1 2 2 2 0 KaiC TniB PF05621.11 KIK66000.1 - 0.022 14.2 0.0 3.3 7.1 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 KIK66000.1 - 0.03 14.8 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK66000.1 - 0.04 13.2 0.5 1.7 7.9 0.1 2.7 2 1 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KIK66000.1 - 0.041 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KIK66000.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KIK66000.1 - 0.061 12.8 0.3 0.2 11.1 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KIK66000.1 - 0.071 13.0 0.0 0.34 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KIK66000.1 - 0.074 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KIK66000.1 - 0.12 12.0 0.0 0.61 9.8 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KIK66000.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase p450 PF00067.22 KIK66002.1 - 1.8e-12 46.8 0.1 1.9e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK66003.1 - 2.4e-45 155.2 0.0 4.1e-43 147.8 0.1 2.7 2 1 0 2 2 2 2 Cytochrome P450 GP3 PF03076.14 KIK66003.1 - 0.015 15.4 0.2 0.03 14.4 0.2 1.4 1 0 0 1 1 1 0 Equine arteritis virus GP3 p450 PF00067.22 KIK66004.1 - 5.1e-62 210.1 0.0 6.3e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ANAPC4 PF12896.7 KIK66005.1 - 0.022 14.3 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 SKG6 PF08693.10 KIK66006.1 - 0.018 14.5 3.0 0.026 13.9 3.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KIK66006.1 - 0.023 15.6 0.0 0.024 15.5 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pox_A14 PF05767.12 KIK66006.1 - 0.035 14.3 0.2 0.045 13.9 0.2 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 LAX PF15681.5 KIK66006.1 - 0.17 10.7 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X EphA2_TM PF14575.6 KIK66007.1 - 0.0098 16.8 0.0 0.025 15.4 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF2976 PF11190.8 KIK66007.1 - 0.05 13.4 1.3 0.36 10.7 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) DUF2165 PF09933.9 KIK66007.1 - 0.053 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) SKG6 PF08693.10 KIK66007.1 - 0.32 10.4 6.6 0.54 9.7 6.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Col_cuticle_N PF01484.17 KIK66007.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.4 2 1 0 2 2 2 0 Nematode cuticle collagen N-terminal domain PTP_tm PF18861.1 KIK66007.1 - 0.77 9.7 3.5 1.3 9.0 2.6 1.6 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J p450 PF00067.22 KIK66008.1 - 3.5e-63 214.0 0.0 4e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.15 KIK66009.1 - 3.9e-46 157.7 35.4 5e-46 157.4 35.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Formyl_trans_N PF00551.19 KIK66010.1 - 1.7e-40 138.7 0.0 3.5e-20 72.5 0.1 2.0 2 0 0 2 2 2 2 Formyl transferase MOZ_SAS PF01853.18 KIK66011.1 - 6.1e-63 211.7 0.0 2.9e-60 203.0 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 KIK66011.1 - 1.9e-17 62.6 5.7 4.1e-08 32.7 0.1 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 KIK66011.1 - 2.1e-07 30.7 0.1 4.9e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KIK66011.1 - 0.035 14.5 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pinin_SDK_memA PF04696.13 KIK66011.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region N6-adenineMlase PF10237.9 KIK66012.1 - 3.7e-37 127.6 0.0 4.6e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase RicinB_lectin_2 PF14200.6 KIK66013.1 - 1.2e-06 29.1 3.0 0.014 16.1 0.2 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF4807 PF16065.5 KIK66013.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) PAF-AH_p_II PF03403.13 KIK66016.1 - 2.1e-18 66.0 0.0 2.2e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIK66016.1 - 1.2e-05 24.4 0.0 2.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIK66016.1 - 0.046 13.0 0.1 0.67 9.2 0.1 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIK66016.1 - 0.052 13.3 0.0 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KIK66016.1 - 0.21 10.5 1.8 0.6 9.1 0.1 2.3 2 1 1 3 3 3 0 Chlorophyllase PAF-AH_p_II PF03403.13 KIK66018.1 - 2.5e-19 69.1 0.0 2.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIK66018.1 - 2.9e-06 26.4 0.1 6.2e-06 25.3 0.1 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIK66018.1 - 0.0067 15.7 0.1 0.086 12.1 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KIK66018.1 - 0.027 13.5 2.3 0.054 12.5 0.1 2.3 2 1 1 3 3 3 0 Chlorophyllase Abhydrolase_6 PF12697.7 KIK66018.1 - 0.037 14.6 0.1 0.071 13.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KIK66018.1 - 0.048 13.4 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family TRPM_tetra PF16519.5 KIK66020.1 - 0.028 14.5 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Tetramerisation domain of TRPM PAF-AH_p_II PF03403.13 KIK66021.1 - 1.5e-20 73.0 0.0 2.6e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIK66021.1 - 2.3e-05 23.5 0.0 5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KIK66021.1 - 0.00045 20.0 0.0 0.0018 18.0 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK66021.1 - 0.0036 16.6 0.2 0.051 12.8 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIK66021.1 - 0.015 15.1 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KIK66021.1 - 0.078 13.6 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KIK66021.1 - 0.4 9.6 1.5 3.3 6.6 0.0 2.5 2 1 1 3 3 3 0 Chlorophyllase Exo_endo_phos_2 PF14529.6 KIK66022.1 - 0.043 13.6 0.5 2 8.3 0.0 2.7 2 1 1 3 3 3 0 Endonuclease-reverse transcriptase NMU PF02070.15 KIK66025.1 - 0.2 11.6 1.2 0.38 10.7 1.2 1.4 1 0 0 1 1 1 0 Neuromedin U p450 PF00067.22 KIK66026.1 - 7.7e-65 219.4 0.0 9.5e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vps35 PF03635.17 KIK66027.1 - 0 1013.2 1.3 0 1013.0 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 KIK66027.1 - 0.085 12.9 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Endoribonuclease L-PSP Pkinase_Tyr PF07714.17 KIK66029.1 - 2.1e-10 40.3 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK66029.1 - 7.7e-07 28.7 0.0 2.2e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain p450 PF00067.22 KIK66031.1 - 1.8e-57 195.1 0.0 2.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M1 PF01433.20 KIK66032.1 - 2.5e-39 135.1 0.0 3.6e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KIK66032.1 - 7.1e-32 109.8 0.0 1.5e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KIK66032.1 - 4.6e-18 66.1 0.0 7.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KIK66032.1 - 0.072 13.5 3.7 2.3 8.6 3.7 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF4072 PF13284.6 KIK66032.1 - 0.18 12.2 0.1 0.44 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Zn_clus PF00172.18 KIK66033.1 - 4.7e-09 36.2 5.9 8.6e-09 35.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KIK66033.1 - 0.24 11.9 7.8 0.41 11.2 7.8 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Fungal_trans PF04082.18 KIK66034.1 - 1.3e-28 99.8 0.0 1.8e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAHP_synth_1 PF00793.20 KIK66034.1 - 0.08 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family DSS1_SEM1 PF05160.13 KIK66035.1 - 0.047 13.8 1.0 0.087 12.9 1.0 1.4 1 0 0 1 1 1 0 DSS1/SEM1 family F-box-like PF12937.7 KIK66036.1 - 6.1e-08 32.4 0.8 2.6e-07 30.4 0.8 2.2 1 0 0 1 1 1 1 F-box-like Sipho_Gp157 PF05565.11 KIK66036.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 LRR_4 PF12799.7 KIK66036.1 - 0.42 11.1 9.2 16 6.1 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF4200 PF13863.6 KIK66036.1 - 2.9 8.3 4.8 0.46 10.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ArfGap PF01412.18 KIK66037.1 - 1.2e-40 138.2 0.3 1.8e-40 137.6 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Caskin1-CID PF16600.5 KIK66037.1 - 0.17 12.5 5.5 0.61 10.7 5.5 1.9 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain p450 PF00067.22 KIK66038.1 - 6.2e-46 157.1 0.0 7.6e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK66039.1 - 2.6e-54 184.7 0.0 3.4e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zona_pellucida PF00100.23 KIK66039.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Zona pellucida-like domain p450 PF00067.22 KIK66040.1 - 7e-54 183.3 0.0 9.5e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RicinB_lectin_2 PF14200.6 KIK66041.1 - 1e-13 51.8 4.6 8.8e-11 42.4 0.1 3.0 2 2 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK66041.1 - 0.0031 17.8 0.1 0.42 10.9 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Botulinum_HA-17 PF05588.11 KIK66041.1 - 0.12 12.4 0.1 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 Clostridium botulinum HA-17 domain ABA_GPCR PF12430.8 KIK66044.1 - 7.2e-34 117.1 1.3 7.2e-34 117.1 1.3 3.2 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KIK66044.1 - 1.7e-15 56.8 0.1 7.9e-15 54.7 0.0 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Abhydrolase_9_N PF15420.6 KIK66044.1 - 0.084 12.9 3.4 3.5 7.6 2.5 2.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus p450 PF00067.22 KIK66045.1 - 1.8e-08 33.6 0.0 2e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK66046.1 - 3.8e-06 25.9 0.0 6.4e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PDZ_5 PF17817.1 KIK66047.1 - 0.08 13.2 0.0 0.08 13.2 0.0 2.6 3 0 0 3 3 3 0 PDZ domain ADH_N PF08240.12 KIK66051.1 - 1.2e-26 92.8 2.0 1.9e-26 92.1 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK66051.1 - 2.5e-25 88.9 0.8 4.1e-25 88.3 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK66051.1 - 1.4e-05 26.2 0.2 2.2e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TOBE_2 PF08402.10 KIK66051.1 - 0.081 13.1 0.2 0.56 10.4 0.0 2.4 3 0 0 3 3 3 0 TOBE domain Aminotran_1_2 PF00155.21 KIK66052.1 - 5e-38 131.2 0.0 6.3e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK66052.1 - 0.0034 16.0 0.0 0.0057 15.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KIK66052.1 - 0.22 10.2 0.0 0.57 8.8 0.0 1.8 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain F-box-like PF12937.7 KIK66053.1 - 7e-07 29.0 0.1 1.1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK66053.1 - 9.6e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 F-box domain YL1 PF05764.13 KIK66054.1 - 2.5e-31 109.7 23.6 2.5e-31 109.7 23.6 3.9 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 KIK66054.1 - 5.3e-14 51.7 0.1 9.4e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Roughex PF06020.11 KIK66054.1 - 0.26 10.4 13.6 0.031 13.4 7.8 2.2 2 0 0 2 2 2 0 Drosophila roughex protein p450 PF00067.22 KIK66055.1 - 6.9e-62 209.7 0.0 8.7e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nucleocapsid-N PF11030.8 KIK66055.1 - 0.057 13.4 0.5 0.11 12.5 0.5 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N DOT1 PF08123.13 KIK66056.1 - 1.1e-17 64.3 0.2 1.2e-17 64.2 0.2 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_20 PF12147.8 KIK66056.1 - 0.016 14.4 0.0 0.017 14.3 0.0 1.0 1 0 0 1 1 1 0 Putative methyltransferase L51_S25_CI-B8 PF05047.16 KIK66057.1 - 1.3e-10 41.0 0.1 2.5e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF4748 PF15932.5 KIK66057.1 - 4.1 7.2 5.3 7.8 6.3 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) GET2 PF08690.10 KIK66060.1 - 7.3e-11 42.3 0.0 1.9e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 GET complex subunit GET2 F-box-like PF12937.7 KIK66063.1 - 4e-09 36.2 3.3 4e-09 36.2 3.3 3.3 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 KIK66063.1 - 0.00014 22.2 6.6 1.3 9.5 0.0 5.5 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK66063.1 - 0.001 18.9 1.2 0.004 17.0 1.2 2.1 1 0 0 1 1 1 1 F-box domain U1snRNP70_N PF12220.8 KIK66063.1 - 0.16 12.6 0.3 0.4 11.4 0.0 1.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CNOT11 PF10155.9 KIK66064.1 - 5.1e-09 36.3 0.0 1.5e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 11 dDENN PF03455.19 KIK66064.1 - 0.11 12.4 0.0 1 9.4 0.0 2.4 3 0 0 3 3 3 0 dDENN domain UBX PF00789.20 KIK66065.1 - 9e-09 35.4 0.0 2.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KIK66065.1 - 2.8e-08 33.4 0.0 5.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Gluconate_2-dh3 PF13618.6 KIK66065.1 - 0.1 12.8 0.5 0.2 11.9 0.5 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Peptidase_M15 PF01427.17 KIK66065.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase APG6_N PF17675.1 KIK66065.1 - 2.1 8.9 21.8 4.8 7.7 21.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region F-box-like PF12937.7 KIK66066.1 - 8.3e-09 35.2 2.0 2.2e-08 33.9 2.0 1.8 1 0 0 1 1 1 1 F-box-like NOC3p PF07540.11 KIK66066.1 - 0.14 12.7 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein F-box-like PF12937.7 KIK66067.1 - 4.2e-09 36.1 5.8 5.2e-09 35.9 4.6 1.8 1 1 0 1 1 1 1 F-box-like ACC_central PF08326.12 KIK66067.1 - 0.09 11.0 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF2730 PF10805.8 KIK66067.1 - 0.12 12.5 0.4 0.19 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) F-box-like PF12937.7 KIK66068.1 - 2e-10 40.4 1.9 2.9e-10 39.9 1.1 1.8 2 0 0 2 2 2 1 F-box-like DUF2730 PF10805.8 KIK66068.1 - 0.033 14.3 0.2 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) MLD PF11647.8 KIK66068.1 - 0.1 12.9 0.1 0.37 11.1 0.1 1.8 1 1 0 1 1 1 0 Membrane Localization Domain Rep_1 PF01446.17 KIK66068.1 - 0.19 11.2 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Replication protein ACC_central PF08326.12 KIK66068.1 - 0.2 9.8 0.1 0.23 9.6 0.1 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region LSM PF01423.22 KIK66069.1 - 3.3e-09 36.3 0.0 4.8e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 LSM domain TFIIS_C PF01096.18 KIK66071.1 - 1.8e-18 66.1 8.7 4.4e-18 64.8 0.6 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIK66071.1 - 1.2e-07 31.4 5.4 2e-06 27.5 0.6 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KIK66071.1 - 7.4e-05 22.7 8.3 0.0034 17.4 0.4 2.7 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 KIK66071.1 - 0.00067 19.0 10.4 0.82 9.2 0.0 4.1 4 0 0 4 4 4 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 KIK66071.1 - 0.0007 19.2 9.9 0.017 14.8 4.1 3.0 2 1 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DUF523 PF04463.12 KIK66071.1 - 0.0057 16.7 0.2 0.0069 16.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) DUF35_N PF12172.8 KIK66071.1 - 0.0079 16.1 4.8 0.98 9.4 0.0 3.9 4 0 0 4 4 4 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Nudix_N_2 PF14803.6 KIK66071.1 - 0.0099 15.8 11.1 0.034 14.1 2.3 3.3 2 2 0 2 2 2 1 Nudix N-terminal IBR PF01485.21 KIK66071.1 - 0.013 15.7 8.2 0.085 13.1 0.2 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 KIK66071.1 - 0.018 15.2 4.3 1.2 9.4 0.0 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KIK66071.1 - 0.018 14.9 6.2 0.17 11.8 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF2752 PF10825.8 KIK66071.1 - 0.028 14.5 1.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) FYDLN_acid PF09538.10 KIK66071.1 - 0.043 14.5 2.6 0.14 12.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2387 PF09526.10 KIK66071.1 - 0.045 13.9 6.4 0.5 10.6 0.2 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) CpXC PF14353.6 KIK66071.1 - 0.066 13.3 7.9 7.4 6.6 1.5 3.5 2 1 0 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.10 KIK66071.1 - 0.069 13.3 12.2 4.7 7.4 0.0 3.9 3 1 0 3 3 3 0 Zinc ribbon domain Mu-like_Com PF10122.9 KIK66071.1 - 0.088 12.3 3.6 5.4 6.5 0.4 2.7 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-C4pol PF14260.6 KIK66071.1 - 0.094 13.2 2.9 0.46 11.0 0.1 2.5 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Rubredoxin_2 PF18073.1 KIK66071.1 - 0.11 12.2 13.0 1.8 8.4 0.2 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain HypA PF01155.19 KIK66071.1 - 0.13 12.3 6.5 5.3 7.1 6.5 2.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3268 PF11672.8 KIK66071.1 - 0.14 12.5 0.7 0.14 12.5 0.7 2.7 2 1 1 3 3 3 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 KIK66071.1 - 0.16 12.0 13.6 0.073 13.1 1.8 3.4 2 2 1 3 3 3 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KIK66071.1 - 0.27 11.2 13.5 3.7 7.6 0.9 3.6 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_9 PF14369.6 KIK66071.1 - 0.32 11.3 7.8 51 4.3 0.0 3.9 3 1 1 4 4 4 0 zinc-ribbon zinc_ribbon_2 PF13240.6 KIK66071.1 - 0.41 10.4 16.2 2.1 8.2 5.7 3.5 3 1 0 3 3 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 KIK66071.1 - 0.73 10.3 8.9 4.3 7.8 0.5 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 KIK66071.1 - 0.89 9.1 13.9 0.81 9.3 3.7 3.2 2 2 0 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 KIK66071.1 - 1.4 8.6 9.2 5.5 6.7 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-IS66 PF13005.7 KIK66071.1 - 1.5 9.3 10.8 13 6.3 0.1 3.5 4 0 0 4 4 3 0 zinc-finger binding domain of transposase IS66 UPF0547 PF10571.9 KIK66071.1 - 1.6 8.9 14.5 2.8 8.1 0.4 3.5 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 Methyltransf_13 PF08421.11 KIK66071.1 - 1.6 9.0 6.6 34 4.8 0.1 3.5 3 1 1 4 4 4 0 Putative zinc binding domain zf-C4_Topoisom PF01396.19 KIK66071.1 - 2 8.2 12.7 4.5 7.1 2.0 3.9 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger RecR PF02132.15 KIK66071.1 - 2.3 7.9 4.9 11 5.7 2.3 2.8 2 1 0 2 2 2 0 RecR protein DNA_RNApol_7kD PF03604.13 KIK66071.1 - 3 7.6 8.7 41 4.0 2.4 3.6 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Auto_anti-p27 PF06677.12 KIK66071.1 - 3.7 7.8 11.4 1.9 8.7 1.2 3.1 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.14 KIK66071.1 - 4.6 7.6 7.6 20 5.6 0.8 3.0 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-RRN7 PF11781.8 KIK66071.1 - 4.8 7.0 12.7 17 5.2 0.6 4.2 5 0 0 5 5 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 KIK66071.1 - 5.1 7.1 12.4 21 5.1 0.1 4.0 3 1 1 4 4 4 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 KIK66071.1 - 5.1 7.0 7.1 21 5.0 0.0 3.7 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO DUF4379 PF14311.6 KIK66071.1 - 7.5 7.0 10.3 10 6.6 0.8 3.6 3 1 1 4 4 4 0 Probable Zinc-ribbon domain F-box-like PF12937.7 KIK66072.1 - 8.8e-09 35.1 2.3 8.8e-09 35.1 2.3 1.8 2 0 0 2 2 2 1 F-box-like Prefoldin PF02996.17 KIK66072.1 - 0.016 15.1 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF5082 PF16888.5 KIK66072.1 - 0.074 13.3 0.2 0.55 10.5 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 KIK66072.1 - 0.088 12.4 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1460 PF07313.12 KIK66072.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) F-box PF00646.33 KIK66072.1 - 0.46 10.4 3.8 4.3 7.3 3.8 2.5 1 1 0 1 1 1 0 F-box domain Furin-like_2 PF15913.5 KIK66073.1 - 2.3e-09 37.4 16.2 2.3e-09 37.4 16.2 6.8 1 1 5 6 6 6 2 Furin-like repeat, cysteine-rich VSP PF03302.13 KIK66073.1 - 4.2e-05 22.6 163.6 0.001 18.0 34.6 6.5 2 1 4 6 6 6 3 Giardia variant-specific surface protein GF_recep_IV PF14843.6 KIK66073.1 - 0.00026 20.8 32.7 0.00026 20.8 32.7 5.9 1 1 5 6 6 6 3 Growth factor receptor domain IV EGF_2 PF07974.13 KIK66073.1 - 0.0019 18.5 10.0 0.0019 18.5 10.0 12.6 12 3 1 13 13 13 2 EGF-like domain Laminin_EGF PF00053.24 KIK66073.1 - 0.0033 17.5 17.1 0.0033 17.5 17.1 9.4 2 2 4 6 6 6 1 Laminin EGF domain DUF4381 PF14316.6 KIK66073.1 - 0.073 13.3 4.8 0.13 12.5 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) BatD PF13584.6 KIK66073.1 - 0.17 10.6 0.3 0.25 10.1 0.3 1.1 1 0 0 1 1 1 0 Oxygen tolerance LapA_dom PF06305.11 KIK66073.1 - 0.41 10.5 1.7 0.72 9.7 1.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HMG_box PF00505.19 KIK66074.1 - 8.1e-09 35.8 2.2 2.9e-06 27.6 0.7 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66074.1 - 0.0013 19.3 0.2 0.0027 18.3 0.2 1.5 1 1 0 1 1 1 1 HMG-box domain DUF2582 PF10771.9 KIK66074.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) NAD_binding_9 PF13454.6 KIK66075.1 - 0.00021 21.3 0.0 0.0011 18.9 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIK66075.1 - 0.00081 18.7 0.0 0.012 14.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb1_5 PF04998.17 KIK66076.1 - 1.3e-100 336.3 0.0 1.7e-100 335.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KIK66076.1 - 3.5e-80 269.6 0.0 5e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KIK66076.1 - 2.7e-74 248.9 0.0 4.4e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KIK66076.1 - 7.6e-64 215.1 0.0 1.3e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KIK66076.1 - 1.8e-51 174.2 0.0 4.3e-51 172.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KIK66076.1 - 8.4e-50 168.3 0.3 1.5e-49 167.4 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KIK66076.1 - 2.3e-36 124.0 0.0 4.2e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ADD_DNMT3 PF17980.1 KIK66076.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 F-box-like PF12937.7 KIK66077.1 - 9.4e-05 22.2 1.3 0.00035 20.4 1.3 2.1 1 1 0 1 1 1 1 F-box-like Osmo_CC PF08946.10 KIK66077.1 - 0.14 12.4 0.3 0.31 11.3 0.3 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Glycos_transf_2 PF00535.26 KIK66078.1 - 2.6e-34 118.5 0.0 3.3e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIK66078.1 - 1.4e-15 57.8 0.0 1.7e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIK66078.1 - 0.0032 17.0 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIK66078.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 F-box-like PF12937.7 KIK66079.1 - 5e-10 39.1 3.2 6.3e-10 38.8 2.2 1.8 1 1 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIK66080.1 - 4.2e-61 206.6 0.0 1.1e-60 205.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK66080.1 - 2.9e-28 98.9 0.2 2.4e-20 72.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK66080.1 - 0.00027 20.4 0.8 0.016 14.6 0.0 2.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KIK66080.1 - 0.0029 17.0 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK66080.1 - 0.008 15.2 0.0 0.019 13.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK66080.1 - 0.0084 16.1 0.2 0.077 12.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 KIK66083.1 - 8.6e-48 163.0 38.1 1.3e-47 162.5 38.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vps52 PF04129.12 KIK66084.1 - 0.037 12.8 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family XhlA PF10779.9 KIK66084.1 - 0.085 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Haemolysin XhlA Aldo_ket_red PF00248.21 KIK66086.1 - 6.2e-67 225.9 0.0 7.7e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_syn_2C PF08485.10 KIK66086.1 - 0.98 9.2 2.8 0.74 9.5 0.4 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal TB2_DP1_HVA22 PF03134.19 KIK66087.1 - 8.8e-26 89.6 8.7 1.5e-25 88.9 8.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ost5 PF05251.12 KIK66088.1 - 2.5e-20 72.5 8.4 3e-20 72.3 8.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Nucleopor_Nup85 PF07575.13 KIK66089.1 - 0.045 12.3 0.2 0.083 11.4 0.0 1.4 2 0 0 2 2 2 0 Nup85 Nucleoporin YqzH PF14164.6 KIK66089.1 - 0.072 13.2 0.1 0.24 11.5 0.1 1.9 1 0 0 1 1 1 0 YqzH-like protein IIGP PF05049.13 KIK66090.1 - 3.5e-16 59.2 0.0 3.5e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK66090.1 - 9.6e-08 32.1 2.4 3e-07 30.5 0.0 3.2 3 1 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK66090.1 - 0.00024 21.1 0.0 0.0011 19.0 0.0 2.1 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK66090.1 - 0.00026 21.5 0.4 0.00026 21.5 0.4 4.1 2 2 0 2 2 2 1 ABC transporter TSC22 PF01166.18 KIK66090.1 - 0.059 13.7 0.4 0.059 13.7 0.4 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Dynamin_N PF00350.23 KIK66090.1 - 0.063 13.3 0.4 0.063 13.3 0.4 4.6 3 2 0 3 3 3 0 Dynamin family ETRAMP PF09716.10 KIK66090.1 - 7.1 6.8 6.5 5.6 7.1 0.4 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) IIGP PF05049.13 KIK66091.1 - 3.9e-15 55.8 2.7 4.4e-15 55.6 0.1 2.2 2 1 1 3 3 3 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK66091.1 - 0.00021 21.4 0.0 0.00068 19.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK66091.1 - 0.0069 16.3 0.0 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Herpes_TAF50 PF03326.13 KIK66091.1 - 0.046 12.4 2.9 0.073 11.7 2.9 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) AAA_23 PF13476.6 KIK66091.1 - 0.068 13.7 0.0 0.068 13.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK66091.1 - 0.16 11.7 0.0 0.48 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3540 PF12059.8 KIK66091.1 - 0.61 9.9 9.5 0.13 12.0 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) ABC_tran PF00005.27 KIK66091.1 - 1.4 9.4 6.9 1.3 9.5 0.1 3.3 3 2 0 3 3 3 0 ABC transporter DMPK_coil PF08826.10 KIK66091.1 - 4.4 7.5 11.4 0.39 10.9 1.6 3.7 2 1 1 3 3 3 0 DMPK coiled coil domain like LINES_N PF14694.6 KIK66093.1 - 0.04 13.4 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Lines N-terminus PEPcase PF00311.17 KIK66093.1 - 0.069 11.2 0.1 0.11 10.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DOT1 PF08123.13 KIK66094.1 - 4.6e-60 202.7 0.0 5.9e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KIK66094.1 - 0.0054 17.3 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66094.1 - 0.0061 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK66094.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KIK66094.1 - 0.12 12.2 0.0 0.42 10.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 KIK66095.1 - 1.8e-18 66.5 8.5 8.6e-08 32.6 0.5 3.2 3 0 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.6 KIK66095.1 - 0.02 15.5 0.3 0.081 13.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 KIK66096.1 - 2.8e-07 31.1 0.2 4.4e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK66096.1 - 0.0018 18.3 0.1 0.0054 16.7 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aldo_ket_red PF00248.21 KIK66099.1 - 6.7e-71 238.9 0.0 7.5e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3552 PF12072.8 KIK66101.1 - 0.00015 21.2 26.8 0.00015 21.2 26.8 4.3 1 1 2 3 3 3 2 Domain of unknown function (DUF3552) Thiolase_N PF00108.23 KIK66102.1 - 2e-16 60.2 0.0 4.7e-15 55.7 0.0 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK66102.1 - 3.8e-06 26.5 0.1 2.3e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK66102.1 - 1.5e-05 24.7 0.1 0.023 14.3 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK66102.1 - 0.0003 20.6 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glycos_transf_3 PF00591.21 KIK66103.1 - 3.2e-75 253.0 0.0 6.2e-75 252.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIK66103.1 - 8.7e-08 31.9 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain SLATT_1 PF18181.1 KIK66104.1 - 0.43 10.5 2.8 0.72 9.8 2.5 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 MFS_1 PF07690.16 KIK66105.1 - 3.6e-14 52.5 34.1 3.6e-14 52.5 34.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK66105.1 - 1.7e-12 47.3 6.1 1.7e-12 47.3 6.1 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 LRR_4 PF12799.7 KIK66107.1 - 2.4 8.7 8.2 17 6.0 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DNA_methylase PF00145.17 KIK66108.1 - 2.7e-24 86.1 0.0 5.3e-20 72.0 0.0 2.3 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase PHD PF00628.29 KIK66109.1 - 1.2e-10 41.1 6.6 1.9e-10 40.4 6.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIK66109.1 - 0.00059 19.3 4.0 0.0011 18.5 4.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KIK66109.1 - 0.11 12.5 1.7 0.23 11.5 1.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_3 PF13922.6 KIK66109.1 - 0.2 12.0 0.2 0.63 10.5 0.2 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx FGF-BP1 PF06473.12 KIK66110.1 - 0.56 10.0 5.5 0.53 10.1 0.1 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) FYVE PF01363.21 KIK66113.1 - 1.9e-15 56.7 2.8 3.7e-15 55.8 2.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 KIK66113.1 - 0.02 15.1 1.5 0.046 14.0 1.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Hamartin PF04388.12 KIK66113.1 - 0.042 12.5 4.8 0.045 12.4 4.8 1.2 1 0 0 1 1 1 0 Hamartin protein Hid1 PF12722.7 KIK66113.1 - 0.48 8.5 2.9 0.74 7.9 2.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.16 KIK66115.1 - 2.2e-28 99.2 35.8 2.2e-28 99.2 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK66115.1 - 1.9e-05 23.3 0.5 3.5e-05 22.4 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KIK66116.1 - 4.1e-30 104.9 29.2 4.1e-30 104.9 29.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK66116.1 - 0.00012 20.7 0.5 0.0002 19.9 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_ribbon_SprT PF17283.2 KIK66119.1 - 0.73 9.8 11.0 2.7 8.0 0.1 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain ArsA_ATPase PF02374.15 KIK66120.1 - 8.4e-112 373.3 1.1 9.9e-112 373.1 1.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KIK66120.1 - 5.7e-14 52.4 0.1 2.2e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KIK66120.1 - 7.8e-12 45.4 0.0 1.8e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KIK66120.1 - 8.6e-06 25.4 0.1 3.2e-05 23.6 0.0 1.9 3 0 0 3 3 3 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KIK66120.1 - 2.2e-05 24.0 0.1 5.9e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KIK66120.1 - 7.2e-05 22.3 5.0 0.00021 20.8 1.2 2.9 1 1 2 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KIK66120.1 - 0.00014 21.6 0.7 0.0026 17.4 0.1 2.5 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KIK66120.1 - 0.005 16.6 0.0 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIK66120.1 - 0.034 13.7 0.7 0.2 11.2 0.7 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK66120.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein VirC1 PF07015.11 KIK66120.1 - 0.066 12.5 0.5 0.17 11.2 0.1 1.9 2 1 0 2 2 2 0 VirC1 protein ATP_bind_1 PF03029.17 KIK66120.1 - 0.095 12.5 1.2 1.2 8.8 1.2 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 KIK66122.1 - 8.1e-27 94.1 52.4 2.5e-23 82.6 41.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Forkhead PF00250.18 KIK66123.1 - 2.5e-22 78.9 0.0 2.6e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain LdpA_C PF12617.8 KIK66125.1 - 0.0017 18.0 0.1 0.0051 16.4 0.0 1.8 2 0 0 2 2 2 1 Iron-Sulfur binding protein C terminal LdpA_C PF12617.8 KIK66126.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Peptidase_C2 PF00648.21 KIK66127.1 - 2.7e-67 226.9 0.1 2.4e-66 223.8 0.1 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Dicty_REP PF05086.12 KIK66127.1 - 4.2 5.2 8.9 6.1 4.7 8.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DIOX_N PF14226.6 KIK66128.1 - 4.2e-26 92.0 0.0 6.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK66128.1 - 6.1e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KIK66129.1 - 1e-45 156.6 0.1 1.3e-45 156.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidase PF01425.21 KIK66130.1 - 1.4e-77 261.6 1.8 2.7e-73 247.5 0.4 2.0 2 0 0 2 2 2 2 Amidase NACHT PF05729.12 KIK66131.1 - 7.9e-07 29.1 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66131.1 - 1.4e-06 28.8 0.0 3.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK66131.1 - 1.6e-06 28.6 0.1 8.6e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK66131.1 - 0.00025 21.0 0.6 0.002 18.1 0.0 2.4 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK66131.1 - 0.0021 18.3 0.0 0.0084 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK66131.1 - 0.033 13.4 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KIK66131.1 - 0.066 13.0 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KIK66131.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HGD-D PF06050.13 KIK66131.1 - 0.16 11.7 0.0 7.7 6.2 0.0 2.9 3 0 0 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component Ku PF02735.16 KIK66132.1 - 4.1e-29 101.8 0.2 7.5e-29 100.9 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KIK66132.1 - 3.6e-26 91.7 0.1 1.1e-25 90.0 0.1 1.9 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KIK66132.1 - 1.1e-07 31.8 0.4 2.7e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KIK66132.1 - 2.6e-05 24.5 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK66132.1 - 0.13 12.9 0.0 0.69 10.6 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain Ras PF00071.22 KIK66133.1 - 1.3e-64 216.7 0.1 1.5e-64 216.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK66133.1 - 2.7e-34 118.0 0.1 5.1e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK66133.1 - 8.2e-15 54.7 0.2 1.1e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK66133.1 - 1.4e-06 28.0 0.2 3.2e-06 26.8 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK66133.1 - 1.4e-05 25.0 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIK66133.1 - 4.5e-05 23.5 0.0 0.00019 21.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK66133.1 - 8.3e-05 22.0 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KIK66133.1 - 0.0021 17.6 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 KIK66133.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KIK66133.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIK66133.1 - 0.041 13.6 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK66133.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KIK66133.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Septin AAA PF00004.29 KIK66133.1 - 0.13 12.7 0.0 0.86 10.0 0.0 2.0 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Actin PF00022.19 KIK66134.1 - 1.6e-41 142.3 0.0 1.5e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Actin Ribosomal_L14e PF01929.17 KIK66135.1 - 4.8e-29 100.7 1.3 7e-29 100.1 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KIK66135.1 - 5.6e-06 26.1 0.6 1.6e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 KOW motif Oxidored_q4 PF00507.19 KIK66136.1 - 0.074 13.2 0.3 0.074 13.2 0.3 3.1 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DEAD PF00270.29 KIK66137.1 - 1.3e-45 155.3 0.0 2.3e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK66137.1 - 1.1e-32 112.6 0.0 1.9e-29 102.2 0.0 3.3 2 1 1 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KIK66137.1 - 0.0076 15.1 0.0 0.024 13.5 0.0 1.8 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Epimerase PF01370.21 KIK66138.1 - 4e-20 72.3 0.0 5.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK66138.1 - 1.5e-13 50.4 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK66138.1 - 6.9e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK66138.1 - 1.9e-10 40.9 0.0 6.6e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK66138.1 - 1.6e-08 34.1 0.0 7.4e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIK66138.1 - 3.1e-07 30.2 0.1 4.7e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KIK66138.1 - 9.5e-06 25.6 0.1 2.1e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66138.1 - 1.2e-05 24.6 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK66138.1 - 4.5e-05 23.0 0.2 0.00018 21.0 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KIK66138.1 - 0.051 12.7 0.1 0.19 10.8 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain P2X_receptor PF00864.19 KIK66138.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 ATP P2X receptor ADH_zinc_N PF00107.26 KIK66139.1 - 2.6e-25 88.9 0.1 4.3e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK66139.1 - 4.5e-22 78.0 5.0 9.9e-22 76.9 5.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK66139.1 - 0.00022 22.3 0.0 0.00047 21.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KIK66140.1 - 2.3e-16 60.0 0.0 4.1e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIK66140.1 - 3.7e-10 39.4 0.0 1.3e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KIK66140.1 - 1.8e-09 37.1 0.0 2.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK66140.1 - 1.6e-07 31.1 0.1 3.5e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK66140.1 - 2e-07 31.1 0.0 4.8e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIK66140.1 - 8.8e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK66140.1 - 1.8e-05 24.3 0.2 6.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KIK66140.1 - 0.0006 19.0 0.0 0.00087 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIK66140.1 - 0.0034 17.3 0.1 0.0097 15.8 0.1 1.8 2 0 0 2 2 2 1 KR domain Oxysterol_BP PF01237.18 KIK66141.1 - 9.7e-86 287.9 0.0 3.4e-83 279.5 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein tRNA-synt_1c PF00749.21 KIK66142.1 - 2.7e-88 295.9 0.0 3.8e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain UDPGT PF00201.18 KIK66143.1 - 1.8e-06 27.0 0.1 2.5e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIK66143.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Zn_clus PF00172.18 KIK66144.1 - 7.4e-06 26.0 11.9 1.1e-05 25.4 11.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAGP PF05507.11 KIK66144.1 - 0.23 11.9 1.4 0.34 11.3 1.4 1.2 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Zn_clus PF00172.18 KIK66145.1 - 0.0055 16.8 14.8 0.0098 16.0 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C2 PF00648.21 KIK66146.1 - 2.2e-66 223.9 0.1 2.2e-66 223.9 0.1 2.4 2 1 0 2 2 2 1 Calpain family cysteine protease Tyosinase_C PF18132.1 KIK66146.1 - 0.11 13.2 0.4 0.36 11.5 0.3 1.9 2 0 0 2 2 2 0 Tyosinase C-terminal domain DUF2052 PF09747.9 KIK66146.1 - 1.8 8.7 10.0 3.5 7.7 10.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF966 PF06136.13 KIK66146.1 - 4.7 6.8 11.4 7.7 6.1 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 KIK66146.1 - 7 5.3 5.5 10 4.8 5.5 1.2 1 0 0 1 1 1 0 Presenilin LRR_4 PF12799.7 KIK66147.1 - 0.14 12.7 8.6 8.1 7.0 0.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) p450 PF00067.22 KIK66148.1 - 6.6e-46 157.0 0.0 9.2e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GTP_CH_N PF12471.8 KIK66149.1 - 2e-83 278.9 0.0 2.8e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KIK66149.1 - 2.6e-15 56.4 0.0 4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF5367 PF17329.2 KIK66150.1 - 0.0063 16.6 6.5 0.0063 16.6 6.5 2.9 3 0 0 3 3 3 1 Family of unknown function (DUF5367) YqhR PF11085.8 KIK66151.1 - 0.013 15.5 0.3 0.017 15.1 0.3 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR PDGLE PF13190.6 KIK66152.1 - 0.13 12.2 2.4 0.56 10.1 2.4 2.1 1 1 0 1 1 1 0 PDGLE domain Adeno_E3_CR2 PF02439.15 KIK66152.1 - 0.99 9.2 2.8 1.9 8.3 2.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF456 PF04306.13 KIK66153.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Romo1 PF10247.9 KIK66153.1 - 0.011 16.1 0.3 0.028 14.8 0.3 1.7 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.6 KIK66153.1 - 0.19 11.5 6.1 0.34 10.7 6.1 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KIK66153.1 - 0.31 11.1 7.2 0.73 9.9 7.2 1.6 1 0 0 1 1 1 0 Glycine zipper HhH-GPD PF00730.25 KIK66156.1 - 3.3e-17 62.9 0.0 5.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIK66156.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KIK66156.1 - 0.034 14.5 1.9 0.062 13.7 1.9 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HATPase_c_3 PF13589.6 KIK66157.1 - 0.00033 20.5 0.4 0.8 9.5 0.0 3.1 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BTB PF00651.31 KIK66157.1 - 0.0078 16.4 0.0 0.028 14.7 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF87 PF01935.17 KIK66157.1 - 0.16 12.0 0.0 2 8.5 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain RACo_linker PF17650.1 KIK66157.1 - 1.6 8.7 3.8 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 RACo linker region EAP30 PF04157.16 KIK66158.1 - 8.3e-70 234.7 0.0 9.4e-70 234.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family IMUP PF15761.5 KIK66159.1 - 4.6 8.0 6.2 69 4.2 0.4 2.5 1 1 0 2 2 2 0 Immortalisation up-regulated protein Beta-lactamase PF00144.24 KIK66161.1 - 3.4e-37 128.4 0.0 5.6e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KIK66161.1 - 0.012 16.1 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) DUF5488 PF17590.2 KIK66161.1 - 0.044 13.5 0.0 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5488) Rbx_binding PF18113.1 KIK66161.1 - 0.12 12.1 0.0 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain Kelch_1 PF01344.25 KIK66162.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 KIK66162.1 - 0.087 13.1 0.1 0.46 10.8 0.1 2.3 1 0 0 1 1 1 0 Kelch motif Esterase_phd PF10503.9 KIK66164.1 - 2e-26 92.9 0.3 2.7e-26 92.4 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIK66164.1 - 8.7e-12 45.0 2.2 1.3e-11 44.4 2.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIK66164.1 - 0.0016 18.1 1.4 0.002 17.8 1.3 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KIK66164.1 - 0.048 13.5 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIK66164.1 - 0.066 13.0 1.0 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK66164.1 - 0.078 11.8 1.0 0.099 11.5 0.9 1.3 1 1 0 1 1 1 0 Carboxylesterase family Ribo_biogen_C PF04034.13 KIK66165.1 - 5.7e-51 171.5 0.0 9.4e-51 170.8 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KIK66165.1 - 1.3e-14 53.7 0.1 1.3e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI p450 PF00067.22 KIK66166.1 - 6.2e-70 236.2 0.0 1.5e-69 235.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Chorismate_synt PF01264.21 KIK66169.1 - 2.1e-139 463.8 0.0 2.4e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Cupin_5 PF06172.11 KIK66171.1 - 7.9e-41 139.5 0.0 9.4e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Ribosomal_L4 PF00573.22 KIK66172.1 - 1e-40 139.5 1.1 1.8e-40 138.7 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KIK66172.1 - 2.8e-29 101.0 3.3 2.8e-29 101.0 3.3 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain EnY2 PF10163.9 KIK66173.1 - 9.3e-16 58.0 0.0 1e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 PAM2 PF07145.15 KIK66174.1 - 3.1e-05 23.3 9.0 0.25 11.1 0.0 4.1 3 0 0 3 3 3 2 Ataxin-2 C-terminal region ApoC-I PF04691.12 KIK66174.1 - 0.28 11.1 3.6 2.4 8.2 0.2 3.6 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) FPP PF05911.11 KIK66174.1 - 0.4 8.8 48.3 0.044 12.0 21.4 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Tup_N PF08581.10 KIK66174.1 - 4.7 7.6 30.3 3.6 8.0 4.0 5.4 4 1 1 5 5 5 0 Tup N-terminal ABC_tran PF00005.27 KIK66175.1 - 1.6e-45 155.0 0.0 1e-21 77.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK66175.1 - 5.2e-16 59.3 3.1 0.00055 19.8 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KIK66175.1 - 1.2e-15 57.3 13.6 7.5e-15 54.7 10.7 3.0 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KIK66175.1 - 9.8e-09 35.0 1.6 0.75 9.2 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK66175.1 - 1.1e-08 35.8 2.4 0.0019 18.7 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 KIK66175.1 - 1.9e-08 34.4 0.0 0.011 15.4 0.0 3.8 3 2 1 4 4 3 2 AAA ATPase domain AAA_29 PF13555.6 KIK66175.1 - 4.2e-08 32.8 0.2 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK66175.1 - 1.9e-06 28.4 0.0 0.079 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KIK66175.1 - 1.3e-05 25.2 0.1 0.083 12.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KIK66175.1 - 5e-05 23.4 0.0 0.081 13.0 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK66175.1 - 0.00018 21.5 1.9 0.21 11.5 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KIK66175.1 - 0.00019 21.8 0.0 0.79 10.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KIK66175.1 - 0.00033 20.8 1.3 0.99 9.4 0.0 3.5 4 0 0 4 4 4 2 Helicase HerA, central domain AAA_18 PF13238.6 KIK66175.1 - 0.001 19.6 0.3 3.5 8.2 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KIK66175.1 - 0.0018 18.0 0.1 2 8.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain MukB PF04310.12 KIK66175.1 - 0.0037 17.1 0.4 2 8.2 0.0 3.8 4 0 0 4 4 4 1 MukB N-terminal NB-ARC PF00931.22 KIK66175.1 - 0.0038 16.5 0.0 2.2 7.4 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain AAA_33 PF13671.6 KIK66175.1 - 0.004 17.3 0.0 9 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK66175.1 - 0.004 16.5 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.6 KIK66175.1 - 0.0041 17.4 0.0 0.47 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KIK66175.1 - 0.0067 16.0 0.1 1.9 8.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain PRK PF00485.18 KIK66175.1 - 0.008 15.9 0.0 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 KIK66175.1 - 0.0093 16.4 0.1 26 5.2 0.0 4.1 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK66175.1 - 0.0095 16.3 1.5 5.1 7.5 0.0 3.1 3 0 0 3 3 3 0 RNA helicase NTPase_1 PF03266.15 KIK66175.1 - 0.011 15.7 1.5 1.6 8.6 0.1 3.3 4 0 0 4 4 4 0 NTPase AAA_30 PF13604.6 KIK66175.1 - 0.015 15.1 0.0 2.5 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK66175.1 - 0.023 14.8 8.6 2.9 7.9 0.0 4.3 3 2 1 4 4 4 0 Dynamin family Roc PF08477.13 KIK66175.1 - 0.03 14.6 0.5 12 6.2 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KIK66175.1 - 0.038 13.6 0.0 19 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KIK66175.1 - 0.041 13.0 2.0 2.6 7.1 0.0 3.0 3 1 0 3 3 3 0 G-protein alpha subunit MarR_2 PF12802.7 KIK66175.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 MarR family MeaB PF03308.16 KIK66175.1 - 0.079 11.9 0.0 21 4.0 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 KIK66175.1 - 0.083 12.5 0.1 2.7 7.6 0.0 2.5 2 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 KIK66175.1 - 0.09 12.8 0.2 13 5.8 0.0 3.2 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KIK66175.1 - 0.1 11.3 4.4 3.9 6.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain Arf PF00025.21 KIK66175.1 - 0.1 12.1 1.2 0.78 9.2 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family SbcCD_C PF13558.6 KIK66175.1 - 0.12 12.6 0.1 7.5 6.9 0.0 3.4 2 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KIK66175.1 - 0.13 12.2 0.2 9 6.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KIK66175.1 - 0.19 12.2 0.7 21 5.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain LAGLIDADG_WhiA PF14527.6 KIK66175.1 - 0.21 11.7 2.5 3.5 7.8 0.2 2.9 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain Asp PF00026.23 KIK66176.1 - 7.5e-14 51.9 0.2 2.7e-06 27.0 0.0 3.4 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIK66176.1 - 0.036 14.7 0.6 0.33 11.6 0.1 2.7 3 0 0 3 3 3 0 Aspartyl protease EphA2_TM PF14575.6 KIK66176.1 - 0.12 13.3 0.0 0.23 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DNA_topoisoIV PF00521.20 KIK66177.1 - 1.8e-123 412.6 0.3 3e-123 411.9 0.3 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIK66177.1 - 2e-50 170.4 0.1 6.6e-50 168.7 0.1 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KIK66177.1 - 1.5e-27 96.2 2.5 3.1e-27 95.1 2.5 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KIK66177.1 - 7.1e-12 45.8 0.2 3.1e-11 43.8 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIK66177.1 - 2.4e-08 34.1 0.0 1.1e-07 32.0 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Ntox17 PF15524.6 KIK66177.1 - 0.012 15.8 2.1 0.7 10.2 0.2 3.2 2 0 0 2 2 2 0 Novel toxin 17 hNIFK_binding PF12196.8 KIK66177.1 - 5.2 6.6 6.1 2.2 7.8 2.0 2.6 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK PIP5K PF01504.18 KIK66178.1 - 4.4e-88 295.1 0.0 1.4e-87 293.4 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cwf_Cwc_15 PF04889.12 KIK66178.1 - 0.014 15.1 2.2 0.014 15.1 2.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mago_nashi PF02792.14 KIK66179.1 - 3e-77 257.6 0.7 3.4e-77 257.4 0.7 1.0 1 0 0 1 1 1 1 Mago nashi protein Thymidylat_synt PF00303.19 KIK66180.1 - 5.7e-105 350.3 0.0 6.4e-105 350.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Clathrin_lg_ch PF01086.17 KIK66181.1 - 3.2e-45 155.0 1.0 3.9e-45 154.7 1.0 1.1 1 0 0 1 1 1 1 Clathrin light chain Trp_repressor PF01371.19 KIK66181.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein DUF4407 PF14362.6 KIK66181.1 - 0.91 8.8 4.4 1.1 8.5 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dor1 PF04124.12 KIK66182.1 - 6.3e-40 136.9 0.0 3.1e-39 134.6 0.0 2.0 1 1 0 1 1 1 1 Dor1-like family Y_phosphatase PF00102.27 KIK66183.1 - 8.4e-48 163.0 0.5 2.7e-21 76.2 0.0 4.9 4 1 0 4 4 4 4 Protein-tyrosine phosphatase Rhodanese PF00581.20 KIK66183.1 - 1.7e-07 31.7 0.0 6.1e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KIK66183.1 - 0.0047 16.9 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KIK66183.1 - 0.048 13.5 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TRAPP PF04051.16 KIK66184.1 - 1.1e-39 135.5 0.0 1.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DHC_N1 PF08385.12 KIK66185.1 - 5.4e-119 398.4 6.0 7.9e-119 397.8 1.8 2.3 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 Gly_radical PF01228.21 KIK66185.1 - 0.15 12.6 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycine radical Mating_N PF12731.7 KIK66185.1 - 0.16 12.1 1.4 10 6.3 0.0 3.7 3 0 0 3 3 3 0 Mating-type protein beta 1 Tim54 PF11711.8 KIK66186.1 - 7.6e-46 156.6 0.0 5.4e-39 134.0 0.1 2.2 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 FUSC-like PF12805.7 KIK66189.1 - 0.031 13.3 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS YL1 PF05764.13 KIK66190.1 - 0.009 16.1 8.1 0.014 15.6 8.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Polyoma_lg_T_C PF06431.11 KIK66190.1 - 0.038 12.9 2.3 0.058 12.3 2.3 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CDC45 PF02724.14 KIK66190.1 - 0.079 11.2 7.4 0.1 10.9 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.6 KIK66190.1 - 0.25 11.5 2.1 0.39 10.9 2.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF5323 PF17257.2 KIK66193.1 - 0.048 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5323) Spc7 PF08317.11 KIK66194.1 - 0.00085 18.3 10.2 0.0013 17.7 10.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein YscO-like PF16789.5 KIK66194.1 - 0.0035 17.4 7.4 0.0053 16.8 7.4 1.3 1 0 0 1 1 1 1 YscO-like protein Peptidase_S49_N PF08496.10 KIK66194.1 - 0.029 14.4 0.8 0.049 13.7 0.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HMMR_N PF15905.5 KIK66194.1 - 0.041 13.4 9.0 0.07 12.6 9.0 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PEP-utilisers_N PF05524.13 KIK66194.1 - 0.041 14.0 2.2 0.11 12.7 2.2 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4201 PF13870.6 KIK66194.1 - 0.08 12.7 7.6 0.16 11.7 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) LRS4 PF10422.9 KIK66194.1 - 0.18 11.4 8.9 0.33 10.5 8.9 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Relaxase PF03432.14 KIK66194.1 - 0.37 10.3 2.5 0.58 9.7 2.5 1.1 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Fez1 PF06818.15 KIK66194.1 - 0.46 10.9 11.0 1.5 9.2 10.3 1.7 1 1 0 1 1 1 0 Fez1 Csm1_N PF18504.1 KIK66194.1 - 0.77 10.1 14.4 0.88 10.0 4.3 3.1 1 1 3 4 4 4 0 Csm1 N-terminal domain DUF4337 PF14235.6 KIK66194.1 - 0.78 9.8 4.0 1.4 9.0 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1664 PF07889.12 KIK66194.1 - 0.88 9.6 2.4 1.5 8.9 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 KIK66194.1 - 0.99 9.9 7.4 2.1 8.9 0.6 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 KIK66194.1 - 1.1 8.6 9.3 0.41 9.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_23 PF13476.6 KIK66194.1 - 1.8 9.0 7.2 3 8.3 7.2 1.4 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 KIK66194.1 - 1.8 9.1 20.0 0.22 12.0 11.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec2p PF06428.11 KIK66194.1 - 2 8.5 11.1 0.12 12.3 1.3 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KIK66194.1 - 3 7.1 12.4 0.081 12.3 2.2 2.2 2 0 0 2 2 2 0 FAM76 protein ATG16 PF08614.11 KIK66194.1 - 3.2 7.9 18.6 22 5.2 0.6 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 KIK66194.1 - 4.9 7.4 7.6 0.91 9.8 0.8 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.8 KIK66194.1 - 6.7 6.8 12.9 8.5 6.4 0.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIK66194.1 - 7 6.7 17.8 7.9 6.6 9.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KIK66194.1 - 7.9 5.8 15.9 23 4.2 1.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KIK66194.1 - 8.9 6.5 10.2 9.6 6.4 1.1 3.1 2 1 1 3 3 2 0 bZIP transcription factor DUF745 PF05335.13 KIK66195.1 - 0.16 11.7 3.0 2.4 7.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) WD40 PF00400.32 KIK66196.1 - 1e-67 222.4 34.2 1.3e-12 48.0 1.2 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66196.1 - 4.7e-28 97.3 0.0 0.0018 18.5 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66196.1 - 1.1e-16 60.8 1.5 0.071 12.1 0.0 6.0 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66196.1 - 8.7e-15 54.2 0.0 0.38 10.8 0.0 5.7 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat DUF4072 PF13284.6 KIK66196.1 - 8e-07 29.4 5.5 19 5.8 0.0 6.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4072) Frtz PF11768.8 KIK66196.1 - 5e-06 25.1 0.0 0.63 8.3 0.0 4.4 2 2 2 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KIK66196.1 - 7.1e-05 22.5 5.0 27 4.9 0.0 5.6 6 0 0 6 6 6 0 PQQ enzyme repeat Nup160 PF11715.8 KIK66196.1 - 7.1e-05 21.6 8.4 7.5 5.1 0.1 5.8 2 2 3 6 6 6 1 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KIK66196.1 - 8.5e-05 21.5 0.0 1 8.0 0.0 4.5 1 1 3 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_3 PF15911.5 KIK66196.1 - 9.2e-05 22.4 0.9 44 4.2 0.0 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1707 PF08044.11 KIK66196.1 - 0.0002 21.3 0.2 28 4.9 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) PQQ_2 PF13360.6 KIK66196.1 - 0.00051 19.7 12.7 0.11 12.1 3.1 3.4 2 1 0 2 2 2 2 PQQ-like domain Ret2_MD PF18528.1 KIK66196.1 - 0.00066 20.0 0.0 16 6.0 0.0 4.3 2 1 3 5 5 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Peptidase_S9_N PF02897.15 KIK66196.1 - 0.0016 17.3 0.1 5.4 5.7 0.0 3.7 2 2 2 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40_like PF17005.5 KIK66196.1 - 0.014 14.7 0.0 45 3.2 0.0 4.4 2 2 4 6 6 6 0 WD40-like domain DUF3313 PF11769.8 KIK66196.1 - 0.027 14.3 0.8 4.8 7.0 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3313) Proteasome_A_N PF10584.9 KIK66196.1 - 2.2 8.0 14.4 1.1e+02 2.6 0.1 6.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KIK66197.1 - 2e-06 27.8 0.7 6.9e-06 26.1 0.7 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66197.1 - 6.6e-05 23.4 0.0 9.8e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66197.1 - 0.00019 21.4 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 KIK66197.1 - 0.00084 19.3 0.2 0.0017 18.3 0.2 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66197.1 - 0.002 18.5 0.1 0.0026 18.2 0.1 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66197.1 - 0.0048 16.1 0.2 0.006 15.8 0.2 1.3 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK66197.1 - 0.011 16.1 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK66197.1 - 0.013 16.1 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK66197.1 - 0.016 15.4 0.1 0.021 15.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK66197.1 - 0.04 14.0 0.4 0.11 12.6 0.3 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KIK66197.1 - 0.052 12.8 0.1 0.063 12.5 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KIK66197.1 - 0.058 12.9 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK66197.1 - 0.067 13.5 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIK66197.1 - 0.086 12.5 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 KIK66197.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK66197.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein 6PF2K PF01591.18 KIK66197.1 - 0.19 11.0 0.0 17 4.6 0.0 2.1 1 1 0 2 2 2 0 6-phosphofructo-2-kinase F-box-like PF12937.7 KIK66200.1 - 8.9e-11 41.5 4.5 1.9e-10 40.5 2.4 2.7 2 0 0 2 2 2 1 F-box-like Med29 PF11568.8 KIK66200.1 - 0.03 14.6 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 HHH_8 PF14716.6 KIK66200.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain F-box PF00646.33 KIK66200.1 - 0.81 9.6 4.7 35 4.4 0.1 3.7 2 1 1 3 3 3 0 F-box domain F-box-like PF12937.7 KIK66201.1 - 7.5e-05 22.5 1.2 0.00018 21.3 1.2 1.7 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK66202.1 - 0.00031 20.6 0.3 0.00091 19.1 0.3 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK66204.1 - 2.3e-09 37.0 8.1 1.3e-08 34.6 8.1 2.2 1 1 0 1 1 1 1 F-box-like APG17 PF04108.12 KIK66204.1 - 0.025 13.7 0.0 0.031 13.4 0.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 CTV_P6 PF06706.11 KIK66204.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein F-box PF00646.33 KIK66204.1 - 1 9.3 5.6 22 5.1 1.8 2.8 2 1 1 3 3 3 0 F-box domain Abhydrolase_3 PF07859.13 KIK66207.1 - 3.4e-13 49.9 0.0 4.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK66207.1 - 2e-08 33.5 0.0 3.9e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KIK66208.1 - 8.1e-15 55.2 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK66208.1 - 1.4e-11 43.9 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2080 PF09853.9 KIK66208.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) zinc_ribbon_10 PF10058.9 KIK66209.1 - 1.4e-19 69.6 0.5 2.8e-19 68.6 0.5 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-4CXXC_R1 PF10497.9 KIK66209.1 - 0.016 15.5 0.4 0.041 14.1 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PhnA_Zn_Ribbon PF08274.12 KIK66209.1 - 0.021 14.8 1.5 0.043 13.8 1.5 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-ACC PF17848.1 KIK66209.1 - 0.027 14.5 1.3 0.057 13.5 1.3 1.6 1 1 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain GMC_oxred_C PF05199.13 KIK66211.1 - 4.2e-08 33.8 0.1 1.3e-07 32.2 0.1 1.9 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK66211.1 - 1.2e-05 24.9 0.0 2.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK66211.1 - 0.00059 19.0 2.5 0.001 18.2 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK66211.1 - 0.002 18.3 1.1 0.0069 16.6 1.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK66211.1 - 0.0035 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK66211.1 - 0.028 15.0 0.2 0.15 12.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK66211.1 - 0.071 12.4 2.5 0.1 11.9 2.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIK66211.1 - 0.12 12.0 0.3 0.23 11.0 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KIK66211.1 - 0.12 11.4 0.4 0.21 10.6 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KIK66211.1 - 0.29 9.8 1.0 0.43 9.2 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PAC1 PF16094.5 KIK66213.1 - 0.05 12.8 0.1 0.062 12.5 0.1 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 HLH PF00010.26 KIK66214.1 - 7.3e-15 54.7 0.1 2e-14 53.3 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1207 PF06727.11 KIK66214.1 - 0.13 11.2 0.1 0.18 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) Na_H_Exchanger PF00999.21 KIK66215.1 - 3.7e-72 243.2 36.1 4.8e-72 242.8 36.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KIK66215.1 - 0.02 15.2 0.0 5.4 7.4 0.0 3.0 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family G-alpha PF00503.20 KIK66216.1 - 2.7e-112 375.5 0.1 3.1e-112 375.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK66216.1 - 8.3e-11 41.6 0.1 1.6e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIK66216.1 - 0.0018 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KIK66216.1 - 0.016 15.4 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KIK66216.1 - 0.025 13.9 0.1 0.063 12.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KIK66216.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein HemX PF04375.14 KIK66219.1 - 0.04 13.2 30.9 0.034 13.4 1.9 3.2 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase LXG PF04740.12 KIK66219.1 - 0.072 12.8 13.6 0.97 9.1 6.3 2.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily DBB PF14545.6 KIK66219.1 - 0.12 12.3 1.3 2 8.3 1.3 2.3 1 1 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, Bcr-Abl_Oligo PF09036.10 KIK66219.1 - 0.15 12.1 8.0 2 8.5 0.6 3.4 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain COG5 PF10392.9 KIK66219.1 - 0.17 12.1 12.5 0.25 11.5 1.6 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Bep_C_terminal PF17841.1 KIK66219.1 - 0.2 11.9 6.5 0.14 12.4 0.5 2.9 2 1 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF1664 PF07889.12 KIK66219.1 - 0.37 10.8 10.3 0.31 11.1 1.6 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KIK66219.1 - 0.65 10.3 19.5 0.87 9.9 1.0 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ING PF12998.7 KIK66219.1 - 0.78 10.4 13.0 4.6 7.9 4.3 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2408 PF10303.9 KIK66219.1 - 0.9 10.1 14.6 30 5.2 14.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) KxDL PF10241.9 KIK66219.1 - 0.99 9.7 14.2 4.1 7.8 1.9 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein Importin_rep_6 PF18829.1 KIK66219.1 - 1.2 9.3 5.5 18 5.5 0.0 2.8 2 1 1 3 3 2 0 Importin repeat 6 DUF948 PF06103.11 KIK66219.1 - 1.6 9.1 10.4 13 6.1 0.6 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 KIK66219.1 - 1.9 9.2 15.0 97 3.7 3.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA ICA69 PF04629.14 KIK66219.1 - 2.1 8.6 13.0 3.6 7.8 13.0 1.4 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain DUF4618 PF15397.6 KIK66219.1 - 3.2 7.1 21.6 0.19 11.1 1.3 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 KIK66219.1 - 3.3 8.2 8.5 29 5.2 0.1 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PRP1_N PF06424.12 KIK66219.1 - 3.5 8.0 19.6 2.8 8.3 17.8 1.8 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal LMBR1 PF04791.16 KIK66219.1 - 6.1 5.6 8.6 7.5 5.3 8.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 KIK66219.1 - 7.1 6.5 24.9 0.52 10.1 2.7 3.7 2 1 0 3 3 3 0 Septum formation initiator FAM76 PF16046.5 KIK66219.1 - 9.9 5.4 14.0 14 5.0 14.0 1.2 1 0 0 1 1 1 0 FAM76 protein Methyltransf_23 PF13489.6 KIK66220.1 - 9.1e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66220.1 - 2.1e-08 34.8 0.0 3.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK66220.1 - 0.0001 22.9 0.0 0.00017 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66220.1 - 0.001 18.5 0.0 0.0039 16.6 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK66220.1 - 0.0064 16.3 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK66222.1 - 9.2e-11 41.8 0.0 1.2e-10 41.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66222.1 - 2e-06 28.4 0.0 3.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66222.1 - 0.0017 17.7 0.0 0.0045 16.4 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK66222.1 - 0.0033 18.1 0.0 0.0074 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK66222.1 - 0.085 13.6 0.0 0.23 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIK66222.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KIK66223.1 - 2.6e-11 43.6 0.0 5.4e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66223.1 - 7.3e-09 36.2 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66223.1 - 2.6e-05 23.7 0.0 0.00011 21.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK66223.1 - 0.0015 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK66223.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Synaptobrevin PF00957.21 KIK66224.1 - 4.7e-15 55.2 0.6 7.7e-15 54.5 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIK66224.1 - 5.5e-12 45.6 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gas_vesicle_C PF01304.17 KIK66224.1 - 0.087 12.8 0.6 0.27 11.3 0.6 1.8 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain p450 PF00067.22 KIK66226.1 - 4.4e-63 213.6 0.0 5.4e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Synaptobrevin PF00957.21 KIK66227.1 - 2.8e-14 52.7 0.2 5.1e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIK66227.1 - 8.2e-12 45.0 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gas_vesicle_C PF01304.17 KIK66227.1 - 0.075 13.0 0.5 0.33 11.0 0.5 2.1 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Methyltransf_23 PF13489.6 KIK66229.1 - 2.6e-13 50.2 0.0 3.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66229.1 - 1e-10 42.1 0.0 1.7e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66229.1 - 1.3e-06 28.0 0.0 2.2e-06 27.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK66229.1 - 2.4e-05 24.9 0.0 3.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK66229.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK66229.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KIK66229.1 - 0.014 16.1 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF202 PF02656.15 KIK66230.1 - 0.005 17.3 6.2 0.011 16.1 3.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Methyltransf_23 PF13489.6 KIK66232.1 - 1.2e-12 47.9 0.0 1.6e-12 47.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66232.1 - 1.7e-09 38.3 0.0 2.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66232.1 - 1.6e-05 24.3 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK66232.1 - 0.00012 22.6 0.0 0.0002 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK66232.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK66232.1 - 0.061 14.1 0.0 0.097 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIK66233.1 - 2.7e-12 46.8 0.0 3.3e-12 46.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66233.1 - 4.4e-09 36.9 0.0 6.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66233.1 - 6.2e-05 22.4 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK66233.1 - 0.001 19.7 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK66233.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF202 PF02656.15 KIK66234.1 - 0.0013 19.2 5.0 0.003 18.0 1.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Trp_oprn_chp PF09534.10 KIK66234.1 - 0.064 13.1 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Hist_rich_Ca-bd PF10529.9 KIK66234.1 - 0.69 10.2 4.2 1.4 9.3 4.2 1.5 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region 60KD_IMP PF02096.20 KIK66235.1 - 5.4e-19 68.7 1.8 8.1e-19 68.1 1.8 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein T3SS_needle_E PF08988.10 KIK66235.1 - 1.7 8.8 6.1 4.1 7.6 6.1 1.6 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle DUF1180 PF06679.12 KIK66235.1 - 10 6.5 14.9 0.37 11.2 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) eIF_4G1 PF12152.8 KIK66236.1 - 0.14 12.4 0.2 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 HD PF01966.22 KIK66238.1 - 1.7e-07 31.4 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 HD domain EF1_GNE PF00736.19 KIK66240.1 - 2.3e-33 114.2 3.2 4.2e-33 113.4 3.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KIK66240.1 - 4.8e-14 52.5 4.9 4.8e-14 52.5 4.9 2.5 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region UvrB PF12344.8 KIK66240.1 - 0.031 14.1 0.1 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Ultra-violet resistance protein B DUF3246 PF11596.8 KIK66240.1 - 0.033 13.6 0.3 0.041 13.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF211 PF02680.14 KIK66240.1 - 0.045 13.9 0.8 0.11 12.7 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 GST_C PF00043.25 KIK66240.1 - 0.16 12.2 1.2 5.6 7.2 0.0 2.9 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 KIK66240.1 - 0.99 9.9 5.3 7.8 7.0 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) CoA_binding PF02629.19 KIK66241.1 - 9.8e-29 99.9 0.4 2.2e-28 98.8 0.4 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KIK66241.1 - 6.2e-21 74.8 0.1 1.5e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 KIK66241.1 - 6.7e-08 32.4 0.0 2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIK66241.1 - 2.9e-05 24.5 0.0 7.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 KIK66241.1 - 0.023 15.5 0.1 0.12 13.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF4453 PF14627.6 KIK66241.1 - 0.17 12.0 0.4 4.3 7.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4453) CAT_RBD PF03123.15 KIK66244.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 CAT RNA binding domain ABC_tran PF00005.27 KIK66246.1 - 8.6e-27 94.3 0.0 7.2e-12 46.0 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK66246.1 - 1.4e-07 31.7 0.2 0.019 14.8 0.1 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIK66246.1 - 0.0028 17.9 0.1 2.8 8.2 0.0 2.9 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIK66246.1 - 0.0038 16.9 0.1 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK66246.1 - 0.011 16.0 0.0 0.34 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 KIK66246.1 - 0.025 14.0 0.0 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KIK66246.1 - 0.028 13.6 0.0 2.8 7.1 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.6 KIK66246.1 - 0.067 13.7 0.3 0.11 12.9 0.3 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 KIK66246.1 - 0.081 10.4 0.0 0.11 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 KIK66246.1 - 0.21 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KIK66246.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 KIK66246.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIK66247.1 - 1.6e-06 28.1 0.9 7.4e-06 26.0 0.9 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66247.1 - 4.8e-05 23.8 0.0 5.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66247.1 - 0.00045 20.2 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 KIK66247.1 - 0.0011 18.8 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66247.1 - 0.0014 19.1 0.0 0.0019 18.6 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66247.1 - 0.009 15.2 0.4 0.018 14.3 0.4 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KIK66247.1 - 0.02 15.1 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK66247.1 - 0.02 15.3 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KIK66247.1 - 0.037 13.7 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase CbiA PF01656.23 KIK66247.1 - 0.053 13.6 0.4 0.21 11.7 0.6 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KIK66247.1 - 0.077 13.5 0.0 0.095 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK66247.1 - 0.097 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KIK66247.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIK66247.1 - 0.12 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK66247.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KIK66247.1 - 0.16 11.6 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.6 KIK66247.1 - 0.19 12.0 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK66248.1 - 2.2e-51 170.7 19.2 1.1e-11 45.1 0.4 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66248.1 - 8.8e-23 80.4 0.1 0.003 17.8 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66248.1 - 9.7e-14 51.0 0.6 0.0091 15.0 0.0 4.3 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66248.1 - 1.8e-07 30.9 3.2 0.86 9.6 0.0 4.5 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK66248.1 - 4.2e-05 22.4 1.3 6.7 5.2 0.0 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK66248.1 - 5.2e-05 22.7 3.6 2.8 7.2 0.1 4.4 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF5046 PF16465.5 KIK66248.1 - 0.00016 21.3 0.6 0.23 10.9 0.1 3.2 1 1 3 4 4 4 1 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 KIK66248.1 - 0.00029 20.5 9.7 0.00054 19.6 7.5 2.3 1 1 2 3 3 3 2 PQQ-like domain WD40_like PF17005.5 KIK66248.1 - 0.00067 19.1 0.0 3.5 6.8 0.0 3.7 2 1 2 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 KIK66248.1 - 0.0011 19.4 6.6 0.34 11.5 0.2 4.3 4 1 0 4 4 4 1 PQQ-like domain Frtz PF11768.8 KIK66248.1 - 0.0035 15.7 0.0 5.1 5.3 0.0 3.7 1 1 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 KIK66248.1 - 0.0056 16.6 0.5 1.1e+02 2.9 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1707 PF08044.11 KIK66248.1 - 0.0077 16.3 0.1 56 3.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) Peptidase_S9_N PF02897.15 KIK66248.1 - 0.023 13.5 0.1 20 3.8 0.0 3.5 1 1 3 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Me-amine-dh_H PF06433.11 KIK66248.1 - 0.083 11.7 0.0 1.9 7.3 0.0 2.1 1 1 2 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Proteasome_A_N PF10584.9 KIK66248.1 - 3.3 7.5 5.3 95 2.8 0.1 3.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK66251.1 - 1.2e-130 421.6 56.8 1.3e-11 44.8 0.4 12.8 13 0 0 13 13 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66251.1 - 1.1e-43 147.4 3.7 0.02 15.2 0.0 12.2 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66251.1 - 2e-22 79.6 9.1 0.91 8.4 0.0 12.0 1 1 10 12 12 12 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66251.1 - 2e-17 62.7 17.7 6.9 6.7 0.0 11.8 12 0 0 12 12 11 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK66251.1 - 2.2e-09 37.4 0.6 5.4e-09 36.2 0.6 1.6 1 1 0 1 1 1 1 NACHT domain DUF4072 PF13284.6 KIK66251.1 - 1.8e-08 34.7 12.3 38 4.8 0.0 11.2 12 0 0 12 12 12 0 Domain of unknown function (DUF4072) PQQ PF01011.21 KIK66251.1 - 5.2e-06 26.1 6.4 64 3.7 0.0 9.4 11 0 0 11 11 11 0 PQQ enzyme repeat DUF727 PF05303.12 KIK66251.1 - 7.4e-06 26.0 0.5 0.085 12.9 0.0 7.0 7 4 4 11 11 11 1 Protein of unknown function (DUF727) Peptidase_S9_N PF02897.15 KIK66251.1 - 2.5e-05 23.3 9.8 6.3 5.5 0.0 7.4 1 1 5 9 9 9 3 Prolyl oligopeptidase, N-terminal beta-propeller domain Me-amine-dh_H PF06433.11 KIK66251.1 - 5.4e-05 22.2 0.1 6.3 5.6 0.0 5.3 1 1 6 9 9 9 1 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 KIK66251.1 - 0.00041 20.8 0.0 0.00085 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66251.1 - 0.0005 20.0 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 NTPase WD40_3 PF15911.5 KIK66251.1 - 0.00083 19.3 8.0 1.3e+02 2.7 0.0 9.3 11 0 0 11 11 11 0 WD domain, G-beta repeat APS_kinase PF01583.20 KIK66251.1 - 0.0058 16.5 0.2 0.01 15.8 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK66251.1 - 0.0072 15.5 0.3 0.044 13.0 0.2 2.3 2 1 0 2 2 2 1 NB-ARC domain PQQ_2 PF13360.6 KIK66251.1 - 0.0087 15.7 37.7 0.48 10.0 10.5 4.8 1 1 2 4 4 4 3 PQQ-like domain AAA PF00004.29 KIK66251.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SLH PF00395.20 KIK66251.1 - 0.024 14.6 0.0 5.7e+02 0.6 0.0 6.5 9 0 0 9 9 8 0 S-layer homology domain AAA_22 PF13401.6 KIK66251.1 - 0.035 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK66251.1 - 0.05 14.0 0.1 0.29 11.6 0.1 2.4 1 0 0 1 1 1 0 RNA helicase Retrotran_gag_2 PF14223.6 KIK66252.1 - 5.7e-08 32.5 0.1 1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Vps53_N PF04100.12 KIK66254.1 - 0.0028 16.7 0.1 0.0035 16.4 0.1 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Laminin_II PF06009.12 KIK66254.1 - 0.021 14.8 1.9 0.03 14.3 1.9 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF2514 PF10721.9 KIK66254.1 - 0.025 14.6 3.7 0.04 14.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TMF_DNA_bd PF12329.8 KIK66254.1 - 0.039 13.9 2.3 0.079 13.0 2.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KIK66254.1 - 0.15 12.7 0.8 0.27 11.9 0.3 1.8 2 0 0 2 2 2 0 SlyX Spc7_N PF15402.6 KIK66255.1 - 0.32 9.2 17.5 0.51 8.5 17.5 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NACHT PF05729.12 KIK66257.1 - 8.6e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66257.1 - 3.3e-05 24.3 0.0 4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66257.1 - 0.00032 20.6 0.1 0.00078 19.4 0.0 1.6 2 0 0 2 2 2 1 NTPase APS_kinase PF01583.20 KIK66257.1 - 0.001 19.0 0.2 0.0021 18.0 0.2 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66257.1 - 0.0028 18.1 0.1 0.0042 17.5 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66257.1 - 0.0051 16.0 0.3 0.0083 15.3 0.3 1.5 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK66257.1 - 0.011 16.1 0.1 0.025 14.9 0.1 1.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KIK66257.1 - 0.021 15.0 0.2 0.026 14.7 0.2 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK66257.1 - 0.061 13.9 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK66257.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK66257.1 - 0.075 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK66257.1 - 0.08 12.7 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase DUF2075 PF09848.9 KIK66257.1 - 0.094 11.9 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KIK66257.1 - 0.1 12.6 0.9 0.33 11.0 0.7 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KIK66257.1 - 0.18 11.5 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_17 PF13207.6 KIK66257.1 - 0.18 12.2 0.1 0.37 11.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK66257.1 - 0.22 11.2 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK66258.1 - 1.5e-45 152.2 14.5 7e-12 45.7 0.5 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66258.1 - 7.7e-18 64.6 0.1 0.0022 18.3 0.0 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66258.1 - 4.3e-11 42.3 0.4 0.16 10.9 0.0 4.0 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66258.1 - 1.4e-09 37.6 0.7 0.61 10.1 0.0 4.5 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK66258.1 - 2.3e-06 27.3 1.7 0.66 10.0 0.0 4.3 4 0 0 4 4 4 1 PQQ enzyme repeat DUF4072 PF13284.6 KIK66258.1 - 2.5e-05 24.6 0.2 9.6 6.7 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) Nup160 PF11715.8 KIK66258.1 - 9.2e-05 21.3 0.8 11 4.6 0.0 3.9 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 KIK66258.1 - 0.00075 18.4 0.9 1.5 7.5 0.0 3.5 1 1 3 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_2 PF13360.6 KIK66258.1 - 0.00075 19.1 9.7 0.06 12.9 4.0 2.4 1 1 1 2 2 2 2 PQQ-like domain SLH PF00395.20 KIK66258.1 - 0.00079 19.4 0.0 58 3.8 0.0 4.3 4 0 0 4 4 4 0 S-layer homology domain Frtz PF11768.8 KIK66258.1 - 0.0013 17.1 0.0 1.7 6.9 0.0 3.2 1 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK66258.1 - 0.0015 17.5 0.0 0.95 8.3 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) WD40_like PF17005.5 KIK66258.1 - 0.0015 17.9 0.0 11 5.2 0.0 3.6 2 1 2 4 4 4 0 WD40-like domain PQQ_3 PF13570.6 KIK66258.1 - 0.0017 18.7 6.3 14 6.3 0.2 4.1 2 1 2 4 4 4 0 PQQ-like domain WD40_3 PF15911.5 KIK66258.1 - 0.0029 17.6 0.1 12 5.9 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat MucBP_2 PF17965.1 KIK66258.1 - 0.037 14.6 1.9 49 4.6 0.1 4.0 4 0 0 4 4 4 0 Mucin binding domain DUF4265 PF14085.6 KIK66258.1 - 0.11 12.4 0.5 15 5.6 0.0 3.3 1 1 2 4 4 4 0 Domain of unknown function (DUF4265) Proteasome_A_N PF10584.9 KIK66258.1 - 0.15 11.7 7.6 8 6.2 0.4 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Imm17 PF15562.6 KIK66258.1 - 0.17 11.8 0.0 28 4.7 0.0 3.4 3 0 0 3 3 3 0 Immunity protein 17 ABC_tran PF00005.27 KIK66260.1 - 2.4e-21 76.7 0.0 4.7e-10 40.1 0.0 3.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK66260.1 - 0.0012 18.7 1.4 0.053 13.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK66260.1 - 0.0036 17.0 0.1 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIK66260.1 - 0.026 14.0 0.0 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK66260.1 - 0.061 13.8 0.3 0.092 13.2 0.3 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 KIK66260.1 - 0.063 10.8 0.0 0.087 10.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_16 PF13191.6 KIK66260.1 - 0.083 13.3 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK66260.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIK66260.1 - 0.21 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Ploopntkinase1 PF18748.1 KIK66260.1 - 0.21 11.1 0.0 0.44 10.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 NACHT PF05729.12 KIK66262.1 - 2.4e-07 30.8 1.5 1.9e-06 27.9 1.5 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66262.1 - 7.8e-05 23.1 0.0 9.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66262.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 KIK66262.1 - 0.00036 20.5 0.2 0.0006 19.7 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66262.1 - 0.0019 18.6 0.0 0.0025 18.2 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66262.1 - 0.0052 16.0 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Cytidylate_kin PF02224.18 KIK66262.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 KIK66262.1 - 0.012 16.0 0.1 0.019 15.4 0.1 1.3 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK66262.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK66262.1 - 0.031 14.8 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK66262.1 - 0.052 12.8 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KIK66262.1 - 0.066 13.6 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK66262.1 - 0.07 13.2 1.0 0.12 12.5 0.4 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KIK66262.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 KIK66262.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KIK66262.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK66262.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK66262.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 KIK66262.1 - 0.23 10.9 0.4 0.35 10.3 0.4 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 KIK66262.1 - 0.27 10.5 0.1 0.45 9.8 0.1 1.3 1 0 0 1 1 1 0 ATPase MipZ WD40 PF00400.32 KIK66263.1 - 4.3e-79 258.4 34.0 8e-12 45.5 1.6 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66263.1 - 7.8e-31 106.2 0.8 0.0094 16.2 0.0 8.0 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66263.1 - 5.9e-19 68.2 1.8 0.023 13.6 0.0 7.1 1 1 5 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66263.1 - 1e-11 44.5 7.1 1.3 9.0 0.0 7.4 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK66263.1 - 0.00018 20.9 0.0 5.5 6.2 0.0 5.2 3 2 3 6 6 6 1 WD40-like domain WD40_3 PF15911.5 KIK66263.1 - 0.00059 19.8 2.4 1.6e+02 2.4 0.0 6.6 7 0 0 7 7 7 0 WD domain, G-beta repeat Nbas_N PF15492.6 KIK66263.1 - 0.00059 19.2 7.0 13 5.0 0.0 5.3 1 1 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK66263.1 - 0.00095 17.6 0.0 13 4.0 0.0 4.8 3 2 2 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz ESPR PF13018.6 KIK66263.1 - 0.1 12.4 1.4 26 4.7 0.0 4.5 5 0 0 5 5 5 0 Extended Signal Peptide of Type V secretion system rOmpB PF12334.8 KIK66263.1 - 0.68 9.4 10.6 12 5.3 0.1 5.7 3 1 5 8 8 8 0 Rickettsia outer membrane protein B WD40 PF00400.32 KIK66265.1 - 1.5e-30 104.8 11.8 7.5e-11 42.4 0.5 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66265.1 - 1.3e-10 41.4 0.0 0.078 13.3 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK66265.1 - 4.6e-09 36.4 0.3 1.6e-08 34.7 0.3 1.9 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KIK66265.1 - 1.8e-06 27.2 0.1 0.36 9.7 0.0 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK66265.1 - 0.00025 21.4 0.0 0.00057 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 KIK66265.1 - 0.00083 19.2 0.4 5.1 7.2 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AAA PF00004.29 KIK66265.1 - 0.00094 19.6 0.0 0.0029 18.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66265.1 - 0.0021 17.3 0.6 0.022 13.9 0.0 2.7 3 1 0 3 3 3 1 NB-ARC domain APS_kinase PF01583.20 KIK66265.1 - 0.0048 16.8 0.7 0.014 15.3 0.2 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK66265.1 - 0.0066 16.4 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KIK66265.1 - 0.017 15.4 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK66265.1 - 0.035 14.5 0.2 0.26 11.7 0.1 2.7 2 0 0 2 2 1 0 RNA helicase BTV_NS2 PF04514.12 KIK66265.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AAA_33 PF13671.6 KIK66265.1 - 0.13 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PQQ PF01011.21 KIK66265.1 - 0.16 12.0 0.1 1.1e+02 3.0 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Cytidylate_kin PF02224.18 KIK66265.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 KIK66270.1 - 5.9e-06 26.3 0.4 1.8e-05 24.8 0.4 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66270.1 - 0.00017 22.0 0.0 0.00022 21.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK66270.1 - 0.0009 19.7 0.0 0.0015 18.9 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK66270.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 KIK66270.1 - 0.0014 18.6 0.2 0.0023 17.9 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK66270.1 - 0.0058 17.0 0.1 0.013 15.9 0.1 1.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KIK66270.1 - 0.006 15.8 0.4 0.011 15.0 0.3 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK66270.1 - 0.015 15.9 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK66270.1 - 0.027 14.7 0.1 0.036 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK66270.1 - 0.035 13.8 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase 6PF2K PF01591.18 KIK66270.1 - 0.042 13.2 0.0 7.6 5.8 0.0 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_29 PF13555.6 KIK66270.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 KIK66270.1 - 0.053 13.6 0.4 0.12 12.5 0.4 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KIK66270.1 - 0.053 12.7 0.1 0.077 12.2 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thymidylate_kin PF02223.17 KIK66270.1 - 0.064 12.9 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 KIK66270.1 - 0.065 12.9 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK66270.1 - 0.069 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KIK66270.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 KIK66270.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 KIK66270.1 - 0.16 9.9 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.27 KIK66270.1 - 0.16 12.5 0.3 0.18 12.3 0.3 1.3 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.17 KIK66270.1 - 0.21 11.6 1.0 0.37 10.8 0.5 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain WD40 PF00400.32 KIK66271.1 - 2.5e-69 227.5 45.2 3.3e-12 46.7 1.2 8.4 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66271.1 - 5.6e-22 77.9 1.6 0.0026 18.0 0.0 6.3 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66271.1 - 5.2e-15 54.9 7.4 0.052 13.5 0.0 6.8 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66271.1 - 1.7e-13 50.3 4.8 0.28 10.1 0.0 6.1 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK66271.1 - 6.1e-08 32.8 0.0 0.082 12.8 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 KIK66271.1 - 2.8e-06 27.3 10.2 0.00099 18.9 1.8 4.1 1 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain PQQ PF01011.21 KIK66271.1 - 3.7e-06 26.6 1.2 19 5.4 0.0 6.2 6 0 0 6 6 6 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIK66271.1 - 9.3e-05 21.4 0.0 0.54 9.1 0.0 3.1 3 0 0 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) WD40_3 PF15911.5 KIK66271.1 - 0.00011 22.2 6.4 6.3 6.9 0.0 6.8 7 0 0 7 7 7 1 WD domain, G-beta repeat DPPIV_N PF00930.21 KIK66271.1 - 0.00062 18.6 0.3 0.081 11.7 0.1 4.0 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Frtz PF11768.8 KIK66271.1 - 0.0024 16.3 0.0 5.9 5.1 0.0 3.9 2 1 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK66271.1 - 0.0025 17.4 14.2 0.7 9.4 0.5 3.3 1 1 1 3 3 3 3 PQQ-like domain Nup160 PF11715.8 KIK66271.1 - 0.0034 16.1 9.0 17 3.9 0.0 5.7 3 2 3 6 6 6 0 Nucleoporin Nup120/160 DUF727 PF05303.12 KIK66271.1 - 0.011 15.8 0.0 53 3.9 0.0 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF727) Plk4_PB1 PF18190.1 KIK66271.1 - 0.049 13.8 0.1 4.3 7.5 0.0 3.6 3 2 3 6 6 6 0 Polo-like Kinase 4 Polo Box 1 DUF1707 PF08044.11 KIK66271.1 - 0.095 12.8 0.1 38 4.5 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) DNase_II PF03265.15 KIK66271.1 - 0.42 9.8 1.8 14 4.9 0.2 3.3 1 1 3 4 4 4 0 Deoxyribonuclease II PAC4 PF16093.5 KIK66272.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 HemY_N PF07219.13 KIK66274.1 - 0.25 11.5 0.6 0.72 10.1 0.6 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Cullin_binding PF03556.15 KIK66275.1 - 5.8e-35 120.3 0.1 9.9e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KIK66275.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Glyco_hydro_115 PF15979.5 KIK66278.1 - 5.6e-124 414.0 0.0 7.8e-124 413.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KIK66278.1 - 1.1e-40 139.3 0.0 1.6e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain PSI_PsaH PF03244.14 KIK66278.1 - 0.14 11.6 0.0 0.43 10.1 0.0 1.8 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI DUF4381 PF14316.6 KIK66279.1 - 0.0059 16.9 0.0 0.0059 16.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) COesterase PF00135.28 KIK66280.1 - 3.1e-86 290.3 0.0 3.4e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK66280.1 - 5e-08 33.1 0.0 1.1e-06 28.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK66281.1 - 4.3e-89 299.7 0.0 4.8e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK66281.1 - 5.1e-08 33.0 0.3 0.0063 16.4 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold WD40 PF00400.32 KIK66282.1 - 1.2e-10 41.8 1.5 0.092 13.7 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66282.1 - 2.6e-07 30.8 0.0 0.38 11.1 0.0 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Dioxygenase_C PF00775.21 KIK66283.1 - 4.2e-10 39.4 0.0 7.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase FANCF PF11107.8 KIK66284.1 - 0.094 11.9 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Stevor PF17410.2 KIK66285.1 - 0.17 11.4 2.3 0.24 10.9 2.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame NUDIX PF00293.28 KIK66286.1 - 3.5e-09 36.8 0.0 6.4e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Pex14_N PF04695.13 KIK66286.1 - 0.00018 22.2 2.2 0.00041 21.0 2.2 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4653 PF15546.6 KIK66286.1 - 0.018 14.7 3.5 0.031 13.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF908 PF06012.12 KIK66286.1 - 0.2 11.0 6.8 0.28 10.5 6.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SR-25 PF10500.9 KIK66286.1 - 0.29 10.7 9.5 0.49 10.0 9.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FXMRP1_C_core PF12235.8 KIK66286.1 - 2.1 9.0 6.0 3.7 8.2 6.0 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Pkinase PF00069.25 KIK66288.1 - 4.9e-34 117.9 0.0 6e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK66288.1 - 8.4e-16 58.0 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK66288.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KIK66288.1 - 0.033 13.8 0.1 0.11 12.1 0.1 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK66288.1 - 0.065 12.6 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK66288.1 - 0.078 12.9 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family PEMT PF04191.13 KIK66289.1 - 1.9e-48 163.2 20.0 1.7e-27 95.9 1.3 3.6 4 0 0 4 4 4 2 Phospholipid methyltransferase ApoLp-III PF07464.11 KIK66289.1 - 0.042 13.9 0.4 0.089 12.9 0.4 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SKICH PF17751.1 KIK66289.1 - 0.07 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 SKICH domain HECW_N PF16562.5 KIK66289.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF4870 PF09685.10 KIK66290.1 - 0.031 14.4 2.3 0.059 13.5 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) LMSTEN PF07988.12 KIK66291.1 - 0.06 12.8 0.0 0.26 10.8 0.0 2.1 1 0 0 1 1 1 0 LMSTEN motif TPR_10 PF13374.6 KIK66291.1 - 4.3 7.3 5.0 23 5.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KIK66292.1 - 8.8e-139 447.3 59.4 6.1e-11 42.7 0.8 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66292.1 - 3.7e-40 136.1 10.5 0.0071 16.6 0.0 14.1 2 1 13 15 15 14 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66292.1 - 2.1e-26 92.7 22.4 0.011 14.7 0.0 13.6 3 2 11 14 14 14 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66292.1 - 4.4e-12 45.6 31.4 3.3 7.8 0.0 13.3 14 0 0 14 14 13 3 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK66292.1 - 9.2e-09 34.1 0.0 2.1 6.6 0.0 7.2 3 2 5 9 9 9 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK66292.1 - 1.5e-07 31.0 0.1 1.1 8.6 0.0 7.8 7 3 3 10 10 10 1 WD40-like domain AAA_16 PF13191.6 KIK66292.1 - 6.5e-06 26.6 0.0 3.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Nup160 PF11715.8 KIK66292.1 - 2.2e-05 23.3 15.9 2 6.9 0.0 10.3 8 4 6 14 14 14 1 Nucleoporin Nup120/160 NACHT PF05729.12 KIK66292.1 - 9e-05 22.4 0.1 0.00072 19.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain WD40_3 PF15911.5 KIK66292.1 - 0.0021 18.0 4.6 1.7e+02 2.3 0.0 8.7 9 1 1 10 10 10 0 WD domain, G-beta repeat DUF3313 PF11769.8 KIK66292.1 - 0.0073 16.1 0.0 11 5.8 0.0 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF3313) APS_kinase PF01583.20 KIK66292.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK66292.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KIK66292.1 - 0.026 15.0 0.0 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Me-amine-dh_H PF06433.11 KIK66292.1 - 0.027 13.3 0.0 2.7 6.8 0.0 3.7 4 1 2 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 KIK66292.1 - 0.038 13.9 2.5 21 5.3 0.0 5.6 7 0 0 7 7 7 0 PQQ enzyme repeat RNA_helicase PF00910.22 KIK66292.1 - 0.066 13.6 0.0 0.39 11.1 0.0 2.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK66292.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain GT-D PF08759.11 KIK66292.1 - 0.14 11.8 0.4 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold NB-ARC PF00931.22 KIK66292.1 - 0.16 11.2 0.1 0.74 8.9 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain DUF4596 PF15363.6 KIK66292.1 - 1.4 9.2 5.0 1.3e+02 2.9 0.0 5.1 5 0 0 5 5 4 0 Domain of unknown function (DUF4596) Cuticle_4 PF15955.5 KIK66292.1 - 2.1 9.1 4.3 93 3.8 0.0 5.1 6 1 0 6 6 5 0 Cuticle protein ESPR PF13018.6 KIK66292.1 - 2.4 8.1 6.2 1.5e+02 2.3 0.0 5.7 7 0 0 7 7 7 0 Extended Signal Peptide of Type V secretion system 2OG-FeII_Oxy_2 PF13532.6 KIK66293.1 - 8.9e-15 55.4 0.0 4.1e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_3 PF00202.21 KIK66294.1 - 1.3e-115 386.3 0.0 1.5e-115 386.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIK66294.1 - 0.00053 19.3 0.0 0.00078 18.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIK66294.1 - 0.093 12.0 0.0 0.36 10.1 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase OST3_OST6 PF04756.13 KIK66308.1 - 0.17 11.2 0.8 0.42 9.9 0.8 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF2418 PF10332.9 KIK66308.1 - 1.4 9.5 4.3 4.4 7.9 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Spore_YtfJ PF09579.10 KIK66309.1 - 0.32 11.2 1.0 0.45 10.7 1.0 1.2 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) FMO-like PF00743.19 KIK66311.1 - 8.2e-26 90.5 0.0 1.1e-22 80.2 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK66311.1 - 4.1e-11 42.7 0.0 8.9e-10 38.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK66311.1 - 2.6e-06 27.3 0.9 0.00026 20.7 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK66311.1 - 7e-06 25.5 0.0 5.5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK66311.1 - 7.6e-06 26.0 0.0 0.00028 20.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK66311.1 - 3.8e-05 23.8 0.0 7.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 KIK66311.1 - 0.0078 15.7 0.1 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 KIK66311.1 - 0.027 13.6 0.0 3 6.9 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KIK66311.1 - 0.053 12.8 0.2 1 8.5 0.0 2.7 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIK66311.1 - 0.11 13.1 0.0 0.5 11.0 0.0 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KIK66312.1 - 2e-57 194.8 0.0 3e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK66312.1 - 1.3e-39 135.9 0.2 2.8e-39 134.9 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK66312.1 - 2.9e-06 26.7 0.1 0.001 18.2 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIK66312.1 - 8.7e-05 22.3 1.1 0.00065 19.4 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK66312.1 - 9.1e-05 21.8 0.4 0.004 16.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KIK66312.1 - 0.00024 20.3 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK66312.1 - 0.00035 20.7 0.6 0.00082 19.6 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK66312.1 - 0.00051 19.4 0.3 0.0015 17.9 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK66312.1 - 0.00055 19.3 0.2 0.13 11.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK66312.1 - 0.04 12.6 0.1 0.061 12.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK66312.1 - 0.13 12.3 0.2 0.29 11.1 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIK66312.1 - 0.15 10.9 0.2 0.3 9.9 0.2 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Arfaptin PF06456.13 KIK66314.1 - 0.02 14.5 0.2 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 Arfaptin-like domain zf-ribbon_3 PF13248.6 KIK66314.1 - 0.042 13.3 0.2 0.093 12.2 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KIK66314.1 - 0.043 13.7 0.1 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain OPT PF03169.15 KIK66315.1 - 1.4e-135 453.4 42.6 1.6e-135 453.2 42.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PsiA PF06952.11 KIK66316.1 - 0.08 12.2 4.0 0.08 12.2 1.5 1.9 2 0 0 2 2 2 0 PsiA protein DUF4710 PF15828.5 KIK66316.1 - 7.8 6.7 10.7 13 6.0 3.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) MULE PF10551.9 KIK66318.1 - 0.093 13.2 0.0 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 MULE transposase domain Pkinase PF00069.25 KIK66320.1 - 1.3e-37 129.6 0.0 1.9e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK66320.1 - 6.7e-21 74.7 0.0 8.1e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK66320.1 - 0.0033 16.8 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KIK66320.1 - 0.067 12.8 0.1 0.7 9.5 0.1 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK66320.1 - 0.069 13.1 1.3 1.3 8.9 0.8 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Serpentine_r_xa PF03383.15 KIK66321.1 - 0.024 14.6 1.6 0.031 14.2 1.6 1.2 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa KDZ PF18758.1 KIK66323.1 - 6.7e-11 42.2 0.0 6.7e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RVP_2 PF08284.11 KIK66324.1 - 0.026 14.3 0.2 0.055 13.2 0.2 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 KIK66324.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Leader_CPA1 PF08252.11 KIK66325.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide PARP_reg PF02877.14 KIK66326.1 - 0.044 13.9 0.0 0.083 13.0 0.0 1.5 1 1 1 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Bacteriocin_II PF01721.18 KIK66326.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Class II bacteriocin VASt PF16016.5 KIK66327.1 - 6e-35 120.9 0.0 1e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KIK66327.1 - 1.2e-21 76.7 0.0 2.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DHR10 PF18595.1 KIK66327.1 - 0.21 11.6 1.2 0.51 10.4 1.2 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CE2_N PF17996.1 KIK66328.1 - 0.00026 20.9 0.1 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal RE_BstXI PF09552.10 KIK66329.1 - 0.034 13.3 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease DUF2274 PF10038.9 KIK66329.1 - 0.076 13.5 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) RNase_P_Rpp14 PF01900.19 KIK66330.1 - 0.012 15.9 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Rpp14/Pop5 family AAA_16 PF13191.6 KIK66333.1 - 1.8e-05 25.2 0.0 2.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK66333.1 - 0.00022 21.2 0.1 0.00032 20.7 0.1 1.4 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 KIK66333.1 - 0.0021 17.9 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK66333.1 - 0.0031 16.7 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.15 KIK66333.1 - 0.0036 17.2 0.0 0.0063 16.4 0.0 1.4 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KIK66333.1 - 0.0052 17.1 0.0 0.0082 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA helicase CbiA PF01656.23 KIK66333.1 - 0.0071 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 KIK66333.1 - 0.01 16.3 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK66333.1 - 0.028 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KIK66333.1 - 0.033 13.4 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KIK66333.1 - 0.053 13.7 0.1 0.064 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK66333.1 - 0.073 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KIK66333.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK66333.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_18 PF13238.6 KIK66333.1 - 0.12 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK66333.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KIK66333.1 - 0.16 12.0 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ResIII PF04851.15 KIK66333.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KIK66333.1 - 0.17 12.4 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KIK66333.1 - 0.18 10.9 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain WD40 PF00400.32 KIK66334.1 - 5.3e-140 451.2 52.1 1.6e-11 44.5 0.0 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66334.1 - 1.7e-39 134.0 6.7 0.01 16.1 0.0 12.6 1 1 13 14 14 14 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66334.1 - 1e-24 87.1 11.9 0.028 13.4 0.2 11.3 2 2 9 12 12 12 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66334.1 - 3.2e-18 65.2 7.2 3.1 7.9 0.0 11.8 12 0 0 12 12 12 5 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK66334.1 - 1.4e-17 63.2 0.0 0.021 13.2 0.0 7.8 3 2 2 7 7 7 5 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK66334.1 - 1.2e-12 47.4 19.5 1.2 7.7 0.2 11.5 8 3 4 13 13 13 7 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK66334.1 - 4.7e-11 42.6 0.1 0.12 11.6 0.0 6.9 3 2 4 9 9 9 3 WD40-like domain Ret2_MD PF18528.1 KIK66334.1 - 4.9e-07 30.0 0.7 40 4.7 0.0 8.6 3 3 8 11 11 11 0 RNA editing 3' terminal uridylyl transferase 2 middle domain PQQ PF01011.21 KIK66334.1 - 4.7e-05 23.1 4.5 13 5.9 0.0 7.4 9 0 0 9 9 9 1 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK66334.1 - 5.2e-05 22.2 4.7 1.4 7.6 0.0 5.7 6 2 2 8 8 8 2 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_3 PF13570.6 KIK66334.1 - 0.00028 21.3 18.3 0.46 11.0 0.1 9.0 9 2 2 11 11 11 1 PQQ-like domain WD40_3 PF15911.5 KIK66334.1 - 0.0071 16.3 0.3 1.6e+02 2.4 0.0 6.3 7 0 0 7 7 7 0 WD domain, G-beta repeat Emaravirus_P4 PF16505.5 KIK66334.1 - 0.22 10.5 0.4 90 1.9 0.0 5.0 6 1 2 8 8 8 0 P4 movement protein of Emaravirus, and the 30K superfamily Pro-kuma_activ PF09286.11 KIK66335.1 - 4.9e-18 65.8 0.1 1.3e-17 64.5 0.1 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Annexin PF00191.20 KIK66336.1 - 1.2e-11 44.5 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Annexin DUF3446 PF11928.8 KIK66336.1 - 0.58 10.5 5.8 2 8.8 5.8 1.9 1 1 0 1 1 1 0 Early growth response N-terminal domain DHHC PF01529.20 KIK66341.1 - 4.1e-33 114.3 4.0 4.1e-33 114.3 4.0 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.21 KIK66341.1 - 3.5 7.8 9.5 18 5.6 10.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger 4HBT PF03061.22 KIK66344.1 - 1.1e-08 35.2 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KIK66344.1 - 6.7e-05 23.4 0.0 8.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KIK66344.1 - 0.00047 19.5 0.1 0.0012 18.2 0.2 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase WD40 PF00400.32 KIK66345.1 - 7.2e-115 371.6 38.0 2.7e-11 43.8 0.1 12.8 12 1 1 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66345.1 - 3.1e-37 126.8 8.8 0.00057 20.1 0.0 11.2 3 2 8 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK66345.1 - 1.1e-19 71.1 7.1 5e-05 23.3 0.1 5.9 1 1 0 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK66345.1 - 9.3e-13 47.7 19.8 0.16 10.6 0.1 10.0 4 3 7 11 11 11 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK66345.1 - 4.9e-12 45.5 1.8 0.45 9.4 0.0 9.2 1 1 6 10 10 10 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66345.1 - 3e-11 43.0 1.2 9.3 6.3 0.1 10.1 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK66345.1 - 3.8e-10 39.6 2.3 3.5 6.8 0.0 9.2 7 2 3 11 11 11 1 WD40-like domain NHL PF01436.21 KIK66345.1 - 5.7e-09 35.6 10.0 0.011 15.8 0.0 8.5 10 0 0 10 10 10 1 NHL repeat potato_inhibit PF00280.18 KIK66345.1 - 2.5e-08 34.5 4.6 17 6.2 0.0 9.0 10 1 0 10 10 10 0 Potato inhibitor I family nos_propeller PF18764.1 KIK66345.1 - 7.7e-06 25.7 11.7 16 5.5 0.0 8.8 10 0 0 10 10 10 0 Nitrous oxide reductase propeller repeat Str_synth PF03088.16 KIK66345.1 - 1.3e-05 25.2 0.0 12 6.1 0.0 6.6 7 2 2 9 9 9 0 Strictosidine synthase Imm17 PF15562.6 KIK66345.1 - 2.8e-05 23.9 0.0 9.4 6.2 0.0 6.4 7 0 0 7 7 6 0 Immunity protein 17 DsbC_N PF10411.9 KIK66345.1 - 0.0013 18.2 4.5 81 2.8 0.0 7.7 10 0 0 10 10 10 0 Disulfide bond isomerase protein N-terminus Coatomer_WDAD PF04053.14 KIK66345.1 - 0.0017 17.5 5.4 10 5.0 0.0 4.9 2 1 2 5 5 5 0 Coatomer WD associated region SdiA-regulated PF06977.11 KIK66345.1 - 0.0044 16.3 0.0 22 4.2 0.0 4.7 4 1 0 5 5 5 0 SdiA-regulated PLL PF18587.1 KIK66345.1 - 0.01 16.0 0.0 3.2 7.9 0.0 4.4 5 2 2 7 7 5 0 PTX/LNS-Like (PLL) domain IKI3 PF04762.12 KIK66345.1 - 0.049 11.6 2.3 2.4 6.0 0.0 3.4 4 1 1 5 5 5 0 IKI3 family DUF1513 PF07433.11 KIK66345.1 - 0.067 12.3 13.5 2.7 7.0 0.0 6.0 3 2 2 6 6 6 0 Protein of unknown function (DUF1513) DUF5122 PF17164.4 KIK66345.1 - 0.35 11.2 6.4 62 4.0 0.0 6.2 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller PQQ_3 PF13570.6 KIK66345.1 - 3 8.4 30.8 13 6.4 0.1 9.6 4 3 7 11 11 11 0 PQQ-like domain HAMP PF00672.25 KIK66346.1 - 5.1e-80 263.7 44.1 1.6e-07 31.6 0.1 14.8 15 0 0 15 15 15 13 HAMP domain APG17 PF04108.12 KIK66346.1 - 2.5e-07 30.2 6.3 0.2 10.7 0.2 5.7 4 3 2 6 6 6 3 Autophagy protein Apg17 SpoIIID PF12116.8 KIK66346.1 - 0.0082 16.2 6.3 27 4.9 0.0 5.8 5 0 0 5 5 5 0 Stage III sporulation protein D HTH_6 PF01418.17 KIK66346.1 - 0.02 14.9 0.8 51 3.9 0.0 5.3 6 0 0 6 6 6 0 Helix-turn-helix domain, rpiR family Spt5-NGN PF03439.13 KIK66346.1 - 0.028 14.3 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section PseudoU_synth_1 PF01416.20 KIK66346.1 - 0.13 12.8 14.1 52 4.3 0.0 7.7 9 0 0 9 9 9 0 tRNA pseudouridine synthase T4SS PF07996.11 KIK66346.1 - 5 7.5 15.3 18 5.6 0.4 5.7 4 1 0 5 5 5 0 Type IV secretion system proteins Peptidase_S9 PF00326.21 KIK66347.1 - 1e-25 90.5 0.0 4.4e-16 59.0 0.0 2.4 1 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK66347.1 - 0.0038 16.5 0.0 0.0094 15.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK66347.1 - 0.15 11.6 0.2 0.65 9.6 0.2 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold p450 PF00067.22 KIK66348.1 - 4.6e-39 134.5 0.0 5.6e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pex14_N PF04695.13 KIK66349.1 - 7.4 7.2 13.5 1.1 9.9 3.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2786 PF10979.8 KIK66352.1 - 2.3 8.2 4.1 4.6 7.2 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Glyco_hydro_47 PF01532.20 KIK66353.1 - 1e-119 400.5 0.0 1.2e-119 400.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Macoilin PF09726.9 KIK66354.1 - 0.22 10.0 2.3 0.27 9.7 2.3 1.2 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 KIK66354.1 - 0.61 10.0 0.0 0.61 10.0 0.0 2.5 1 1 1 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 KIK66355.1 - 0.034 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 KIK66355.1 - 0.092 13.2 8.0 0.019 15.4 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM223 PF14640.6 KIK66355.1 - 0.14 12.3 0.3 0.31 11.2 0.3 1.6 1 1 0 1 1 1 0 Transmembrane protein 223 CNH PF00780.22 KIK66357.1 - 1.3e-06 28.2 0.0 1.3e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 CNH domain MSL1_dimer PF16801.5 KIK66357.1 - 0.081 12.7 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 SUR7 PF06687.12 KIK66358.1 - 7.4e-10 38.8 9.9 2.3e-08 33.9 11.9 2.3 1 1 1 2 2 2 1 SUR7/PalI family HisKA_7TM PF16927.5 KIK66358.1 - 2.6e-06 27.7 2.8 2.6e-06 27.7 2.8 1.7 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase DuoxA PF10204.9 KIK66358.1 - 0.0029 16.6 2.1 0.0029 16.6 2.1 2.1 2 0 0 2 2 2 1 Dual oxidase maturation factor Trp_oprn_chp PF09534.10 KIK66358.1 - 0.0083 15.9 1.0 0.013 15.3 1.0 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) GlpM PF06942.12 KIK66358.1 - 0.015 15.8 1.2 0.015 15.8 1.2 1.9 3 0 0 3 3 3 0 GlpM protein Amastin PF07344.11 KIK66358.1 - 0.36 10.7 9.1 1.6 8.5 9.1 2.1 1 1 0 1 1 1 0 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KIK66358.1 - 1.5 8.7 6.1 0.22 11.4 1.0 2.0 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2393 PF09624.10 KIK66358.1 - 2 8.4 8.3 9.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Phage_holin_3_6 PF07332.11 KIK66358.1 - 5.1 7.2 13.7 7.6 6.6 9.7 2.5 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 KIK66358.1 - 9.5 5.8 11.1 38 3.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) SUR7 PF06687.12 KIK66360.1 - 1e-10 41.6 7.5 4.8e-10 39.4 8.0 1.9 1 1 1 2 2 2 1 SUR7/PalI family HisKA_7TM PF16927.5 KIK66360.1 - 4.4e-06 26.9 2.4 4.4e-06 26.9 2.4 1.8 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase DuoxA PF10204.9 KIK66360.1 - 0.0035 16.4 2.4 0.0035 16.4 2.4 2.1 2 0 0 2 2 2 1 Dual oxidase maturation factor Trp_oprn_chp PF09534.10 KIK66360.1 - 0.011 15.5 0.9 0.017 14.9 0.9 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) GlpM PF06942.12 KIK66360.1 - 0.014 15.8 1.1 0.014 15.8 1.1 1.8 2 0 0 2 2 2 0 GlpM protein Amastin PF07344.11 KIK66360.1 - 0.033 14.0 5.4 0.036 13.9 2.4 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KIK66360.1 - 0.085 12.7 3.3 0.14 12.0 0.4 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF4131 PF13567.6 KIK66360.1 - 3.7 7.2 10.9 20 4.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2393 PF09624.10 KIK66360.1 - 6.3 6.8 10.7 8.4 6.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Glyco_hydro_16 PF00722.21 KIK66361.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Atthog PF18800.1 KIK66362.1 - 8.7 6.2 20.2 1.3 9.0 0.6 2.9 3 0 0 3 3 3 0 Attenuator of Hedgehog Zn_clus PF00172.18 KIK66363.1 - 3.5e-09 36.6 12.7 5.4e-09 36.0 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Costars PF14705.6 KIK66364.1 - 8.7e-22 77.1 0.1 9.5e-22 77.0 0.1 1.0 1 0 0 1 1 1 1 Costars MFS_1 PF07690.16 KIK66365.1 - 5.2e-22 78.2 49.5 2.1e-11 43.4 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLAM PF06214.11 KIK66366.1 - 0.051 13.6 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein Imm1 PF14430.6 KIK66366.1 - 0.09 13.4 0.0 0.092 13.4 0.0 1.1 1 0 0 1 1 1 0 Immunity protein Imm1 Arg_decarb_HB PF17810.1 KIK66370.1 - 0.019 15.2 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain Peptidase_M24 PF00557.24 KIK66370.1 - 0.17 11.5 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase family M24 FeoB_associated PF12669.7 KIK66372.1 - 9.5 6.7 0.0 9.5 6.7 0.0 3.8 5 0 0 5 5 5 0 FeoB-associated Cys-rich membrane protein EF1G PF00647.19 KIK66373.1 - 2.6e-45 152.9 0.1 4.6e-45 152.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KIK66373.1 - 1.2e-10 41.6 0.1 4.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK66373.1 - 4.2e-09 36.5 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK66373.1 - 6.9e-08 32.4 0.1 2e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK66373.1 - 7.8e-08 32.4 0.0 2.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK66373.1 - 2.2e-07 31.2 0.0 6.1e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK66373.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KIK66373.1 - 0.64 10.6 5.7 1.3 9.7 5.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_M16 PF00675.20 KIK66374.1 - 2.4e-25 89.3 0.1 3.4e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK66374.1 - 0.0021 18.1 0.0 0.026 14.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase M16 inactive domain Methyltransf_11 PF08241.12 KIK66375.1 - 2.8e-11 43.9 0.0 5.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK66375.1 - 7.3e-11 42.2 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK66375.1 - 1.9e-10 40.7 0.0 4.3e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66375.1 - 3.5e-10 40.5 0.0 6.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK66375.1 - 2.9e-07 31.1 0.0 8.4e-07 29.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIK66375.1 - 2.7e-05 24.1 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KIK66375.1 - 0.0001 21.8 0.0 0.00024 20.6 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.13 KIK66375.1 - 0.0045 16.5 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KIK66375.1 - 0.0059 16.2 0.0 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIK66375.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KIK66375.1 - 0.026 13.1 0.0 4.8 5.6 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 KIK66375.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 KIK66375.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Auxin_repressed PF05564.12 KIK66376.1 - 4 8.1 8.6 1 10.1 4.2 2.2 1 1 0 2 2 2 0 Dormancy/auxin associated protein DNA_pol_B_palm PF14792.6 KIK66377.1 - 7.8e-30 103.4 0.2 2.1e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KIK66377.1 - 1.1e-22 79.6 0.2 6.9e-22 77.0 0.1 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KIK66377.1 - 4.5e-22 78.0 0.0 1.2e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KIK66377.1 - 9.3e-14 51.5 0.8 1e-11 45.0 1.5 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KIK66377.1 - 1.6e-05 25.4 0.0 0.001 19.6 0.1 2.6 1 1 2 3 3 3 3 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KIK66377.1 - 0.098 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.8 KIK66377.1 - 0.12 12.6 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus HHH PF00633.23 KIK66377.1 - 0.12 12.3 0.1 23 5.1 0.1 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif CE2_N PF17996.1 KIK66379.1 - 0.025 14.6 0.2 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 Carbohydrate esterase 2 N-terminal DUF508 PF04370.12 KIK66379.1 - 0.11 12.2 0.3 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Amnionless PF14828.6 KIK66379.1 - 0.17 10.7 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Amnionless bZIP_1 PF00170.21 KIK66381.1 - 0.00023 21.2 7.6 0.00049 20.1 7.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK66381.1 - 0.006 16.6 8.1 0.014 15.5 8.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Glyco_hydro_18 PF00704.28 KIK66384.1 - 4e-56 191.0 0.3 5.1e-56 190.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 KIK66384.1 - 3.3e-17 62.5 0.0 5.9e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 PX domain Retrotran_gag_2 PF14223.6 KIK66385.1 - 2.3e-06 27.3 0.1 2.5e-06 27.2 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type p450 PF00067.22 KIK66386.1 - 1.8e-39 135.8 0.0 2.1e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BKACE PF05853.12 KIK66387.1 - 0.24 10.7 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme SIX1_SD PF16878.5 KIK66390.1 - 0.064 13.8 0.0 0.075 13.6 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain zf-CCHC PF00098.23 KIK66391.1 - 3e-05 23.9 1.9 3e-05 23.9 1.9 2.1 2 0 0 2 2 2 1 Zinc knuckle DUF1068 PF06364.12 KIK66391.1 - 8.2 6.3 8.0 0.27 11.1 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) Retrotrans_gag PF03732.17 KIK66392.1 - 2e-09 37.6 0.8 3.7e-09 36.7 0.8 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Mt_ATP_synt PF15704.5 KIK66392.1 - 0.026 14.5 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit SHE3 PF17078.5 KIK66393.1 - 0.017 14.9 0.4 0.024 14.4 0.4 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF1053 PF06327.14 KIK66393.1 - 0.062 13.9 1.1 0.12 13.0 1.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) PKcGMP_CC PF16808.5 KIK66395.1 - 0.076 12.9 3.1 8.7 6.3 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK66395.1 - 0.096 13.0 0.9 0.2 12.0 0.9 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 KIK66395.1 - 0.99 8.8 8.3 0.099 12.1 4.0 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 KIK66396.1 - 0.0062 15.5 5.7 0.0088 15.0 5.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KIK66396.1 - 0.013 15.4 5.1 0.7 9.8 0.6 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK66396.1 - 0.016 15.3 0.2 0.039 14.0 0.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Bacillus_HBL PF05791.11 KIK66396.1 - 0.019 14.8 1.2 0.33 10.8 0.4 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3196 PF11428.8 KIK66396.1 - 0.07 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Lectin_N PF03954.14 KIK66396.1 - 0.088 12.6 1.1 0.27 11.0 1.1 1.9 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 KIK66396.1 - 0.15 12.2 0.6 0.33 11.1 0.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KASH_CCD PF14662.6 KIK66396.1 - 0.15 11.8 7.1 0.24 11.2 7.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH LRS4 PF10422.9 KIK66396.1 - 0.21 11.1 2.0 0.33 10.5 2.0 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMF_TATA_bd PF12325.8 KIK66396.1 - 0.23 11.7 5.0 0.55 10.5 5.0 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 KIK66396.1 - 0.23 11.8 6.5 4.8 7.6 0.4 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain ADIP PF11559.8 KIK66396.1 - 0.25 11.4 3.9 0.55 10.3 3.6 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIK66396.1 - 0.31 11.0 5.9 3.7 7.6 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Herpes_BLRF2 PF05812.12 KIK66396.1 - 0.37 10.9 4.0 0.78 9.9 2.4 2.4 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein ABC_tran_Xtn PF12848.7 KIK66396.1 - 0.58 10.2 2.0 1.2 9.2 2.0 1.5 1 0 0 1 1 1 0 ABC transporter Phage_GP20 PF06810.11 KIK66396.1 - 0.66 9.8 5.7 6.4 6.6 0.5 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.9 KIK66396.1 - 0.78 8.8 3.9 1.6 7.8 3.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Wtap PF17098.5 KIK66396.1 - 0.99 9.3 5.3 38 4.2 4.1 2.8 1 1 0 1 1 1 0 WTAP/Mum2p family TolA_bind_tri PF16331.5 KIK66396.1 - 1.7 8.8 4.4 2.6 8.2 2.6 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Sec2p PF06428.11 KIK66396.1 - 1.9 8.5 6.7 0.86 9.6 1.8 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Dzip-like_N PF13815.6 KIK66396.1 - 2.5 8.1 5.8 0.87 9.6 0.2 2.8 2 1 1 3 3 3 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal TPR_1 PF00515.28 KIK66397.1 - 2.4e-13 49.3 2.9 0.00092 18.9 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 KIK66397.1 - 2e-12 47.4 0.0 7.5e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 KIK66397.1 - 7.1e-11 41.4 4.8 0.011 15.8 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK66397.1 - 1e-05 26.1 2.1 0.012 16.2 2.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK66397.1 - 2.4e-05 24.2 1.8 0.46 10.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK66397.1 - 2.5e-05 24.7 2.4 0.00038 20.9 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK66397.1 - 3.2e-05 23.6 0.4 0.21 11.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK66397.1 - 0.00029 21.0 2.2 0.61 10.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK66397.1 - 0.0005 19.7 0.8 0.09 12.5 0.1 2.9 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 KIK66397.1 - 0.0006 20.1 0.8 0.12 12.6 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK66397.1 - 0.0053 16.9 0.1 0.025 14.7 0.2 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK66397.1 - 0.033 15.0 0.7 7.7 7.6 0.3 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK66397.1 - 0.079 13.2 0.1 0.67 10.2 0.0 2.1 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK66397.1 - 0.7 10.7 4.6 7.3 7.5 1.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Retinal PF15449.6 KIK66397.1 - 3.5 5.3 30.2 5.5 4.6 30.2 1.3 1 0 0 1 1 1 0 Retinal protein WD40 PF00400.32 KIK66398.1 - 5.8e-119 384.6 62.6 1.2e-10 41.8 0.2 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66398.1 - 2.3e-35 120.7 14.9 0.0036 17.5 0.0 11.5 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66398.1 - 1.9e-22 79.7 11.1 0.098 11.6 0.0 11.2 1 1 11 12 12 12 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66398.1 - 6.7e-15 54.6 10.4 2.8 8.0 0.0 10.6 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK66398.1 - 5.1e-09 35.0 0.0 0.24 9.7 0.0 7.0 4 1 1 7 7 7 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK66398.1 - 6.3e-07 28.4 26.8 0.66 8.5 0.1 9.2 4 3 7 11 11 11 5 Nucleoporin Nup120/160 WD40_3 PF15911.5 KIK66398.1 - 1.1e-05 25.4 5.0 8.1 6.5 0.0 8.0 9 0 0 9 9 9 1 WD domain, G-beta repeat WD40_like PF17005.5 KIK66398.1 - 1.3e-05 24.7 0.2 34 3.6 0.0 6.9 7 1 2 9 9 9 0 WD40-like domain PQQ PF01011.21 KIK66398.1 - 0.0016 18.3 0.4 56 3.9 0.0 6.4 7 0 0 7 7 7 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIK66398.1 - 0.011 14.6 0.0 5.5 5.8 0.0 3.8 3 1 1 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) bPH_4 PF06713.11 KIK66398.1 - 0.053 13.6 0.1 93 3.2 0.0 4.6 5 0 0 5 5 5 0 Bacterial PH domain Nucleoporin_N PF08801.11 KIK66398.1 - 0.5 9.0 6.2 1.2 7.7 0.4 3.8 1 1 3 4 4 4 0 Nup133 N terminal like PQQ_3 PF13570.6 KIK66398.1 - 0.66 10.5 21.3 0.75 10.4 0.1 7.7 6 3 3 9 9 9 0 PQQ-like domain WD40 PF00400.32 KIK66399.1 - 3.8e-103 334.5 32.4 4.5e-11 43.1 0.1 10.4 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66399.1 - 8.6e-38 128.5 2.8 0.00072 19.8 0.0 9.8 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66399.1 - 1.3e-21 77.0 5.7 0.11 11.4 0.0 9.6 2 2 7 10 10 10 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66399.1 - 5e-15 55.0 0.2 1.5 8.8 0.0 10.0 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK66399.1 - 3.2e-11 43.5 0.2 0.016 15.1 0.0 4.2 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK66399.1 - 5e-08 31.7 0.0 1.3 7.2 0.0 6.4 3 2 4 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK66399.1 - 8.7e-05 22.0 0.0 23 4.2 0.0 6.1 6 2 2 8 8 8 0 WD40-like domain Ret2_MD PF18528.1 KIK66399.1 - 0.00074 19.8 0.2 18 5.8 0.0 6.1 3 2 5 8 8 8 0 RNA editing 3' terminal uridylyl transferase 2 middle domain PQQ PF01011.21 KIK66399.1 - 0.0019 18.0 0.8 25 5.0 0.1 5.6 6 0 0 6 6 6 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK66399.1 - 0.002 18.6 12.0 11 6.6 1.2 6.3 6 0 0 6 6 6 1 PQQ-like domain WD40_3 PF15911.5 KIK66399.1 - 0.0057 16.6 0.0 4.6 7.3 0.0 5.0 5 1 1 6 6 6 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK66399.1 - 0.18 10.4 17.8 4 5.9 0.0 6.8 3 1 3 8 8 8 0 Nucleoporin Nup120/160 NACHT PF05729.12 KIK66400.1 - 6.1e-06 26.3 0.0 1.6e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK66400.1 - 0.00092 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 KIK66400.1 - 0.00094 19.6 0.0 0.0014 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KIK66400.1 - 0.0017 18.2 0.4 0.0063 16.4 0.2 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 KIK66400.1 - 0.0035 17.8 0.0 0.0053 17.2 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK66400.1 - 0.0062 16.9 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KIK66400.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 KIK66400.1 - 0.02 14.9 0.2 0.05 13.7 0.2 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Parvo_NS1 PF01057.17 KIK66400.1 - 0.035 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KIK66400.1 - 0.048 12.9 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KIK66400.1 - 0.099 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK66400.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 KIK66400.1 - 0.12 10.2 0.0 0.12 10.2 0.0 1.2 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.27 KIK66400.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KIK66400.1 - 0.13 12.8 0.1 0.27 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK66400.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KIK66400.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK66400.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase TIP49 PF06068.13 KIK66400.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF87 PF01935.17 KIK66400.1 - 0.17 11.9 0.2 0.27 11.3 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KIK66400.1 - 0.18 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 KIK66401.1 - 1.2e-08 34.4 1.6 0.002 17.9 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK66401.1 - 2.5e-07 30.3 2.5 0.0017 18.3 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat RPAP3_C PF13877.6 KIK66401.1 - 2.6e-06 27.9 0.0 6.4e-06 26.6 0.0 1.7 2 0 0 2 2 1 1 Potential Monad-binding region of RPAP3 TPR_17 PF13431.6 KIK66401.1 - 0.00014 22.0 0.8 0.2 12.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK66401.1 - 0.00076 19.5 1.0 0.23 11.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK66401.1 - 0.0031 18.1 2.3 0.0094 16.6 2.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK66401.1 - 0.038 14.5 2.2 1.8 9.1 1.3 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK66401.1 - 0.05 13.9 2.4 0.22 11.8 2.4 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK66401.1 - 0.17 11.9 1.1 22 5.4 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK66401.1 - 0.22 12.5 3.5 1.4 9.9 1.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat MARVEL PF01284.23 KIK66401.1 - 3.4 7.7 12.4 1.1 9.3 6.9 2.6 1 1 1 2 2 2 0 Membrane-associating domain RPAP3_C PF13877.6 KIK66403.1 - 2e-09 37.9 0.0 3.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Kelch_4 PF13418.6 KIK66405.1 - 1.9e-32 111.0 3.2 5.3e-13 48.8 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KIK66405.1 - 2e-32 110.8 4.9 1.1e-07 32.0 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK66405.1 - 1.5e-16 60.0 6.8 0.0004 20.6 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KIK66405.1 - 3.4e-12 45.7 0.6 0.053 13.1 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KIK66405.1 - 5.1e-11 42.3 2.8 0.023 14.7 0.0 5.9 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KIK66405.1 - 7.4e-06 25.7 1.6 0.47 10.5 0.0 5.4 5 0 0 5 5 5 1 Kelch motif adh_short PF00106.25 KIK66406.1 - 1.9e-39 135.1 0.0 2.5e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66406.1 - 1.9e-31 109.4 0.0 2.8e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66406.1 - 9.4e-14 51.7 0.1 1.3e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KIK66406.1 - 0.02 14.7 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 KIK66406.1 - 0.033 13.5 0.2 2.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NDUF_B12 PF08122.12 KIK66408.1 - 0.11 12.5 0.0 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family p450 PF00067.22 KIK66409.1 - 2.6e-74 250.6 0.0 4.5e-74 249.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RAP1 PF07218.11 KIK66410.1 - 0.089 11.1 2.2 0.099 10.9 2.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.32 KIK66413.1 - 3.9e-119 385.1 43.5 5.8e-12 45.9 0.1 11.8 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66413.1 - 1e-38 131.5 2.3 0.0029 17.9 0.0 10.7 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66413.1 - 6.4e-24 84.5 6.9 0.2 10.5 0.0 11.0 1 1 10 11 11 11 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66413.1 - 1.4e-21 75.9 0.7 2.4 8.2 0.0 10.5 10 0 0 10 10 10 6 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK66413.1 - 1.2e-12 46.9 0.0 0.0076 14.6 0.0 6.4 3 1 3 7 7 7 4 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK66413.1 - 1.7e-12 47.3 0.0 0.074 12.4 0.0 7.0 5 3 2 7 7 7 4 WD40-like domain Nup160 PF11715.8 KIK66413.1 - 2.7e-09 36.2 12.8 6.7 5.2 0.0 8.7 5 2 2 9 9 9 5 Nucleoporin Nup120/160 WD40_3 PF15911.5 KIK66413.1 - 2.4e-07 30.6 1.3 1 9.4 0.0 7.7 8 1 0 8 8 8 1 WD domain, G-beta repeat Ret2_MD PF18528.1 KIK66413.1 - 1.7e-06 28.3 0.1 5.2 7.5 0.0 7.0 4 3 4 8 8 8 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PQQ_2 PF13360.6 KIK66413.1 - 0.00062 19.4 21.3 0.058 13.0 5.9 4.8 1 1 3 4 4 4 3 PQQ-like domain Peptidase_S9_N PF02897.15 KIK66413.1 - 0.00076 18.4 0.4 7.7 5.2 0.0 5.0 4 1 2 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK66413.1 - 0.0025 17.7 1.3 50 4.1 0.0 5.7 6 0 0 6 6 6 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIK66413.1 - 0.0028 16.6 0.0 5.8 5.7 0.0 4.3 3 1 1 5 5 5 1 Methylamine dehydrogenase heavy chain (MADH) DUF4909 PF16253.5 KIK66413.1 - 0.038 13.8 0.1 52 3.7 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4909) VID27 PF08553.10 KIK66413.1 - 0.061 12.4 0.4 17 4.3 0.1 3.1 2 2 1 3 3 3 0 VID27 C-terminal WD40-like domain 5-FTHF_cyc-lig PF01812.20 KIK66413.1 - 0.093 12.6 0.1 28 4.5 0.0 4.3 6 0 0 6 6 5 0 5-formyltetrahydrofolate cyclo-ligase family PALB2_WD40 PF16756.5 KIK66413.1 - 0.13 11.1 2.2 7.2 5.4 0.1 4.1 3 2 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain AAA_16 PF13191.6 KIK66414.1 - 1.3e-06 28.9 0.0 1.7e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK66414.1 - 3e-06 27.2 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 KIK66414.1 - 0.0019 18.1 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK66414.1 - 0.0033 17.4 0.0 0.0088 16.0 0.0 1.6 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KIK66414.1 - 0.0045 17.3 0.0 0.0078 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KIK66414.1 - 0.0055 15.9 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK66414.1 - 0.0082 16.6 0.0 0.0095 16.4 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIK66414.1 - 0.011 14.9 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KIK66414.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIK66414.1 - 0.057 14.0 0.0 0.071 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK66414.1 - 0.058 13.5 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK66414.1 - 0.1 12.7 0.4 0.19 11.8 0.2 1.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 KIK66414.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 KIK66414.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK66414.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.3 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIK66414.1 - 0.2 11.3 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase NAD_binding_8 PF13450.6 KIK66415.1 - 1e-09 38.5 0.2 1.2e-06 28.6 0.0 3.6 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIK66415.1 - 1.7e-09 37.3 0.0 0.0002 20.7 0.0 3.9 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK66415.1 - 2.3e-09 36.9 0.0 1.6e-06 27.6 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK66415.1 - 4.6e-08 32.7 0.0 0.08 12.2 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK66415.1 - 1.1e-07 30.8 0.0 4.5e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 KIK66415.1 - 1.1e-07 31.7 0.0 1.9e-05 24.5 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK66415.1 - 2.9e-05 23.3 0.3 9.5e-05 21.6 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KIK66415.1 - 4.6e-05 23.4 0.0 0.33 10.9 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK66415.1 - 0.00043 19.5 0.2 2.3 7.2 0.0 3.3 4 0 0 4 4 4 2 Lycopene cyclase protein Shikimate_DH PF01488.20 KIK66415.1 - 0.00051 20.1 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KIK66415.1 - 0.00052 19.3 0.0 0.012 14.8 0.0 2.7 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 KIK66415.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK66415.1 - 0.0045 15.8 0.2 0.14 10.8 0.1 2.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KIK66415.1 - 0.0045 16.3 0.0 1.8 7.8 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIK66415.1 - 0.0075 16.8 0.1 0.56 10.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK66415.1 - 0.018 15.4 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KIK66415.1 - 0.024 13.8 0.1 22 4.0 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A F420_oxidored PF03807.17 KIK66415.1 - 0.042 14.4 0.1 5.6 7.6 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ChapFlgA PF13144.6 KIK66415.1 - 0.046 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Sacchrp_dh_NADP PF03435.18 KIK66415.1 - 0.057 13.7 0.3 7.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KIK66416.1 - 3e-22 79.0 19.7 3.9e-22 78.7 19.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK66417.1 - 2.2e-19 69.6 19.4 3e-19 69.1 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YebO PF13974.6 KIK66417.1 - 0.013 15.5 0.1 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 YebO-like protein Lipase_GDSL_2 PF13472.6 KIK66418.1 - 1.2e-12 48.6 0.3 2.3e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK66418.1 - 7.8e-08 32.5 0.1 1.8e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KIK66418.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AA_permease_2 PF13520.6 KIK66419.1 - 6e-41 140.7 50.4 7.9e-41 140.3 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK66419.1 - 4.3e-17 61.9 51.5 7.7e-17 61.0 51.5 1.3 1 1 0 1 1 1 1 Amino acid permease NST1 PF13945.6 KIK66420.1 - 4.2e-56 190.1 1.0 4.2e-56 190.1 1.0 3.3 2 1 0 3 3 3 1 Salt tolerance down-regulator CENP-B_dimeris PF09026.10 KIK66420.1 - 0.0011 19.4 14.2 0.0011 19.4 14.2 5.0 5 1 0 5 5 5 1 Centromere protein B dimerisation domain AAA_16 PF13191.6 KIK66421.1 - 0.00038 20.9 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KIK66421.1 - 0.0041 17.0 0.2 0.0067 16.3 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK66421.1 - 0.014 15.7 0.1 0.035 14.5 0.1 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KIK66421.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 KIK66421.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK66421.1 - 0.057 12.6 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIK66421.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KIK66421.1 - 0.085 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KIK66421.1 - 0.12 12.4 0.6 0.32 11.1 0.6 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KIK66421.1 - 0.26 11.5 0.7 0.7 10.0 0.3 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK66421.1 - 0.33 11.5 1.0 0.89 10.1 0.6 2.0 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 KIK66422.1 - 7.8e-68 222.8 22.1 1.1e-10 41.9 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66422.1 - 1.1e-24 86.6 0.0 0.0058 16.9 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66422.1 - 2.6e-18 65.4 0.8 0.19 11.7 0.0 6.5 6 0 0 6 6 6 6 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66422.1 - 1.7e-17 63.4 2.2 0.14 11.1 0.0 6.0 1 1 4 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK66422.1 - 1.7e-05 24.8 0.0 0.016 15.1 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK66422.1 - 7.6e-05 22.2 5.4 6.6 6.0 0.1 5.1 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KIK66422.1 - 0.00012 22.1 0.7 20 5.3 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat Frtz PF11768.8 KIK66422.1 - 0.00023 19.6 0.0 2.2 6.5 0.0 4.6 1 1 4 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF727 PF05303.12 KIK66422.1 - 0.0004 20.4 0.0 25 5.0 0.0 4.8 3 1 3 6 6 5 0 Protein of unknown function (DUF727) Me-amine-dh_H PF06433.11 KIK66422.1 - 0.0014 17.5 0.0 0.11 11.4 0.0 2.9 2 1 0 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 KIK66422.1 - 0.0015 17.3 5.4 13 4.3 0.1 5.3 2 2 4 6 6 6 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK66422.1 - 0.0032 16.8 0.0 1.6 8.0 0.0 3.8 3 1 2 5 5 5 1 WD40-like domain PQQ PF01011.21 KIK66422.1 - 0.0043 16.9 0.2 26 5.0 0.0 4.9 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_2 PF13360.6 KIK66422.1 - 0.0044 16.6 9.3 0.11 12.1 9.2 2.5 1 1 0 1 1 1 1 PQQ-like domain DUF3313 PF11769.8 KIK66422.1 - 0.009 15.8 0.1 1.3 8.8 0.0 3.0 3 1 1 4 4 4 1 Protein of unknown function (DUF3313) DUF1707 PF08044.11 KIK66422.1 - 0.018 15.1 0.0 46 4.2 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) PQQ_3 PF13570.6 KIK66422.1 - 0.025 15.1 7.2 24 5.6 0.1 5.0 5 1 1 6 6 6 0 PQQ-like domain DUF4265 PF14085.6 KIK66422.1 - 0.11 12.5 0.3 17 5.4 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4265) ESPR PF13018.6 KIK66422.1 - 0.21 11.4 1.0 54 3.7 0.1 4.2 5 0 0 5 5 5 0 Extended Signal Peptide of Type V secretion system Proteasome_A_N PF10584.9 KIK66422.1 - 1.5 8.6 20.9 11 5.8 0.4 6.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature GCV_T_C PF08669.11 KIK66422.1 - 3.9 7.5 4.8 38 4.3 0.1 4.3 4 1 1 5 5 5 0 Glycine cleavage T-protein C-terminal barrel domain Retrotran_gag_2 PF14223.6 KIK66424.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Phage_P2_GpE PF06528.12 KIK66425.1 - 0.048 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE Phage_clamp_A PF16790.5 KIK66427.1 - 0.072 13.5 0.0 2.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage clamp loader A subunit eIF3m_C_helix PF18005.1 KIK66431.1 - 0.029 14.0 0.2 0.059 13.1 0.2 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix DUF1989 PF09347.10 KIK66435.1 - 1.7e-62 209.9 0.0 2.1e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) CE2_N PF17996.1 KIK66438.1 - 0.0016 18.4 0.0 3.9 7.5 0.0 3.2 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DDT PF02791.17 KIK66439.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 DDT domain MFS_1 PF07690.16 KIK66440.1 - 1.4e-34 119.6 55.2 4.5e-28 98.2 10.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK66440.1 - 0.024 13.1 13.4 0.0044 15.5 9.6 1.7 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3043 PF11241.8 KIK66440.1 - 0.25 11.4 0.1 0.93 9.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4181 PF13789.6 KIK66440.1 - 7.1 6.9 8.8 2.5 8.4 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) BTB PF00651.31 KIK66441.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain EB1_binding PF05937.11 KIK66444.1 - 0.23 12.0 5.3 0.35 11.4 5.3 1.2 1 0 0 1 1 1 0 EB-1 Binding Domain COX14 PF14880.6 KIK66444.1 - 2.4 8.1 6.2 0.57 10.1 1.6 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c assembly SR-25 PF10500.9 KIK66444.1 - 5.5 6.5 10.7 8.9 5.8 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AGTRAP PF06396.11 KIK66444.1 - 7.8 6.3 10.6 9.5 6.0 6.2 2.7 1 1 1 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) CE2_N PF17996.1 KIK66447.1 - 0.031 14.3 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal GH43_C2 PF17851.1 KIK66447.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain F-box-like PF12937.7 KIK66448.1 - 0.00088 19.1 0.6 0.0023 17.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK66448.1 - 0.02 14.8 0.4 0.072 13.0 0.4 2.0 1 0 0 1 1 1 0 F-box domain Questin_oxidase PF14027.6 KIK66449.1 - 6.5e-85 285.7 0.6 8.2e-85 285.3 0.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like GATA PF00320.27 KIK66450.1 - 4.4e-25 87.0 19.5 5.3e-15 54.7 3.3 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KIK66450.1 - 1.8e-11 43.6 0.7 3.8e-11 42.6 0.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KIK66450.1 - 0.045 13.9 5.4 2.7 8.2 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KIK66450.1 - 0.15 12.2 5.8 0.97 9.6 0.9 2.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KIK66450.1 - 0.25 11.2 6.0 6.2 6.7 0.4 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIK66450.1 - 0.95 9.0 7.2 0.65 9.6 0.8 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KIK66450.1 - 4.1 6.9 6.5 3.3 7.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KIK66450.1 - 4.7 7.3 9.8 32 4.7 0.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 KIK66450.1 - 7.1 6.8 5.3 6.9 6.8 0.1 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Questin_oxidase PF14027.6 KIK66453.1 - 6.4e-85 285.7 0.2 7.7e-85 285.4 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Hydrophobin PF01185.18 KIK66454.1 - 3e-09 37.4 7.1 4e-09 37.0 7.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Peptidase_S6 PF02395.16 KIK66454.1 - 0.3 9.1 0.5 0.28 9.2 0.5 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease Hydrophobin PF01185.18 KIK66455.1 - 6.3e-05 23.5 0.0 0.00012 22.7 0.0 1.5 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK66456.1 - 3e-10 40.6 2.7 4.1e-10 40.1 2.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DNase_II PF03265.15 KIK66457.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II FMO-like PF00743.19 KIK66458.1 - 3.4e-26 91.8 0.3 2.8e-24 85.4 0.3 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK66458.1 - 1e-22 80.8 0.0 9.3e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK66458.1 - 8.1e-18 64.7 0.0 2.7e-07 30.1 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK66458.1 - 3.2e-12 46.3 0.1 8.6e-10 38.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK66458.1 - 1.5e-06 28.6 0.0 0.023 15.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIK66458.1 - 4.3e-05 23.0 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK66458.1 - 0.001 18.4 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK66458.1 - 0.0015 18.7 0.0 0.036 14.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KIK66458.1 - 0.0048 16.8 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIK66458.1 - 0.0052 15.9 0.0 0.89 8.6 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 KIK66458.1 - 0.0055 16.3 0.0 3.7 7.1 0.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK66458.1 - 0.012 14.7 0.0 0.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KIK66458.1 - 0.035 14.2 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIK66458.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIK66458.1 - 0.085 11.5 0.0 0.58 8.8 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Alpha_kinase PF02816.18 KIK66459.1 - 1.3e-10 41.7 0.0 1.4e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 KIK66463.1 - 3.4e-124 401.1 57.4 5.4e-11 42.9 0.1 13.4 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66463.1 - 1.8e-40 137.1 0.5 0.021 15.1 0.0 11.3 2 2 9 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66463.1 - 3.6e-24 85.3 11.7 0.022 13.7 0.1 11.2 3 2 8 11 11 11 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66463.1 - 8.4e-14 51.1 15.6 3.2 7.8 0.0 10.8 11 0 0 11 11 11 6 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK66463.1 - 4.7e-11 42.9 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KIK66463.1 - 2e-05 23.5 22.7 1.5 7.4 0.0 9.2 4 2 4 11 11 11 3 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KIK66463.1 - 0.00012 20.9 0.0 3.9 6.1 0.0 6.0 2 2 4 7 7 7 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_16 PF13191.6 KIK66463.1 - 0.00013 22.3 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK66463.1 - 0.0021 17.3 0.0 0.076 12.2 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain NTPase_1 PF03266.15 KIK66463.1 - 0.0026 17.7 0.1 0.0078 16.1 0.0 1.8 2 0 0 2 2 1 1 NTPase APS_kinase PF01583.20 KIK66463.1 - 0.0056 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66463.1 - 0.0071 16.8 0.0 0.048 14.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Me-amine-dh_H PF06433.11 KIK66463.1 - 0.032 13.1 0.1 9.4 5.0 0.0 3.8 3 1 1 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) RNA_helicase PF00910.22 KIK66463.1 - 0.11 13.0 0.1 0.32 11.4 0.1 1.8 1 0 0 1 1 1 0 RNA helicase PQQ_2 PF13360.6 KIK66463.1 - 0.18 11.4 28.6 0.075 12.6 10.4 4.5 1 1 3 4 4 4 0 PQQ-like domain WD40_3 PF15911.5 KIK66463.1 - 0.19 11.7 6.0 5e+02 0.8 0.0 7.5 10 0 0 10 10 10 0 WD domain, G-beta repeat Enoyl_reductase PF12241.8 KIK66464.1 - 0.057 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region FMO-like PF00743.19 KIK66466.1 - 6.7e-20 71.0 0.8 1.5e-18 66.5 0.8 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK66466.1 - 1.5e-15 57.2 0.0 3.2e-13 49.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK66466.1 - 3.9e-15 55.8 0.0 1.2e-07 31.3 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK66466.1 - 1.5e-10 40.7 0.1 1.7e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK66466.1 - 4.5e-05 23.9 0.0 0.96 10.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIK66466.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 KIK66467.1 - 3.5e-124 401.1 43.9 7.4e-12 45.6 0.4 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66467.1 - 6.9e-45 151.3 0.2 0.0032 17.7 0.0 11.0 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66467.1 - 1.7e-24 86.4 10.2 0.01 14.8 0.0 10.9 1 1 10 11 11 11 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66467.1 - 1.1e-16 60.3 9.2 1.4 8.9 0.0 10.2 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK66467.1 - 1.2e-12 48.2 0.0 0.0034 17.3 0.0 4.3 1 1 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK66467.1 - 4.1e-08 32.0 0.0 3.4 5.9 0.0 6.9 3 3 3 7 7 7 3 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK66467.1 - 9e-07 28.5 0.0 0.063 12.6 0.0 4.6 4 3 1 5 5 5 1 WD40-like domain Cuticle_4 PF15955.5 KIK66467.1 - 3.7e-06 27.5 4.4 66 4.3 0.0 7.2 7 1 0 8 8 8 0 Cuticle protein PQQ PF01011.21 KIK66467.1 - 1.4e-05 24.7 0.6 38 4.4 0.0 6.8 7 0 0 7 7 7 0 PQQ enzyme repeat DUF727 PF05303.12 KIK66467.1 - 3.3e-05 23.9 0.0 29 4.8 0.0 6.3 4 2 4 8 8 8 0 Protein of unknown function (DUF727) PQQ_2 PF13360.6 KIK66467.1 - 5e-05 23.0 23.1 0.00031 20.4 9.2 4.0 1 1 3 4 4 4 3 PQQ-like domain Nup160 PF11715.8 KIK66467.1 - 7.6e-05 21.6 16.3 3.4 6.2 0.1 8.4 1 1 6 10 10 10 2 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 KIK66467.1 - 0.00011 21.2 0.3 2.8 6.7 0.0 4.4 2 1 2 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Nbas_N PF15492.6 KIK66467.1 - 0.00072 19.0 8.7 6.1 6.1 0.0 7.1 1 1 5 8 8 8 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.21 KIK66467.1 - 0.013 14.3 0.1 21 3.7 0.0 4.7 3 3 2 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_3 PF15911.5 KIK66467.1 - 0.024 14.6 12.1 1.9e+02 2.2 0.0 8.6 11 0 0 11 11 11 0 WD domain, G-beta repeat CBP_BcsQ PF06564.12 KIK66467.1 - 0.1 12.0 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Proteasome_A_N PF10584.9 KIK66467.1 - 3 7.6 23.6 19 5.1 0.2 9.2 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KIK66469.1 - 3.8e-08 33.4 0.0 7.9e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66469.1 - 1.3e-06 29.0 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66469.1 - 0.0004 20.4 0.0 0.00093 19.1 0.0 1.5 2 0 0 2 2 2 1 NTPase APS_kinase PF01583.20 KIK66469.1 - 0.0012 18.7 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK66469.1 - 0.0052 16.0 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK66469.1 - 0.0093 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK66469.1 - 0.018 15.5 0.1 0.033 14.6 0.1 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK66469.1 - 0.028 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK66469.1 - 0.028 14.6 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK66469.1 - 0.062 12.5 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KIK66469.1 - 0.11 12.6 1.6 0.19 11.8 0.2 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 KIK66469.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Thymidylate_kin PF02223.17 KIK66469.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 KIK66469.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK66469.1 - 0.24 12.0 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK66470.1 - 7e-78 254.6 30.2 2.6e-11 43.9 0.7 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66470.1 - 8.7e-29 99.7 0.0 0.0029 17.9 0.0 7.4 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66470.1 - 1.3e-19 69.6 8.3 1.1 9.3 0.0 8.6 8 0 0 8 8 8 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66470.1 - 3.2e-17 62.5 2.7 0.42 9.5 0.0 7.9 1 1 6 8 8 8 6 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK66470.1 - 2.3e-07 30.9 0.0 0.0091 15.9 0.0 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A DUF1707 PF08044.11 KIK66470.1 - 2.1e-05 24.5 0.2 18 5.5 0.0 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1707) DPPIV_N PF00930.21 KIK66470.1 - 3.9e-05 22.6 0.0 0.72 8.5 0.0 4.2 1 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.8 KIK66470.1 - 6.6e-05 21.8 5.2 11 4.6 0.0 6.1 5 2 1 7 7 7 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK66470.1 - 0.00023 20.8 14.3 0.097 12.2 3.7 3.8 1 1 1 3 3 3 2 PQQ-like domain Frtz PF11768.8 KIK66470.1 - 0.001 17.5 0.0 6.5 4.9 0.0 4.7 3 2 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK66470.1 - 0.001 18.0 0.1 1.7 7.4 0.0 3.1 2 1 0 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 KIK66470.1 - 0.0014 18.4 0.3 1.3e+02 2.8 0.0 6.0 7 0 0 7 7 7 0 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK66470.1 - 0.0017 17.2 0.1 5 5.8 0.0 4.3 2 1 3 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF3313 PF11769.8 KIK66470.1 - 0.0044 16.9 4.0 0.73 9.6 0.2 4.6 3 1 2 5 5 5 1 Protein of unknown function (DUF3313) WD40_3 PF15911.5 KIK66470.1 - 0.029 14.4 2.1 82 3.3 0.0 5.7 7 0 0 7 7 7 0 WD domain, G-beta repeat BAT PF15915.5 KIK66470.1 - 0.55 10.1 7.7 13 5.7 0.4 3.9 2 1 1 4 4 4 0 GAF and HTH_10 associated domain Proteasome_A_N PF10584.9 KIK66470.1 - 8.8 6.1 21.8 1.2e+02 2.5 0.1 7.7 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature RE_HindVP PF09519.10 KIK66473.1 - 0.14 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease Neural_ProG_Cyt PF06567.11 KIK66474.1 - 0.058 13.6 0.1 0.063 13.5 0.1 1.0 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Plavaka PF18759.1 KIK66475.1 - 6.6e-16 58.4 0.1 8.9e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase DALR_1 PF05746.15 KIK66475.1 - 0.2 11.8 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 DALR anticodon binding domain PTCB-BRCT PF12738.7 KIK66477.1 - 0.0029 17.5 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KIK66477.1 - 0.049 14.0 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Asp_Glu_race PF01177.22 KIK66477.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase RVP_2 PF08284.11 KIK66480.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4800 PF16057.5 KIK66484.1 - 0.0037 16.6 0.2 0.026 13.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Plavaka PF18759.1 KIK66487.1 - 1.1e-57 195.8 0.0 1.2e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase HTH_52 PF18576.1 KIK66488.1 - 0.092 13.0 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3517 PF12030.8 KIK66489.1 - 0.0078 15.2 0.1 0.0095 14.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) Retrotrans_gag PF03732.17 KIK66491.1 - 0.0081 16.4 0.0 0.044 14.0 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein HR1 PF02185.16 KIK66492.1 - 0.027 14.6 0.1 0.039 14.1 0.1 1.2 1 0 0 1 1 1 0 Hr1 repeat Spc7 PF08317.11 KIK66493.1 - 0.02 13.8 8.6 0.028 13.3 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LRS4 PF10422.9 KIK66493.1 - 0.057 13.0 6.7 0.099 12.2 6.7 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 PKcGMP_CC PF16808.5 KIK66493.1 - 0.067 13.0 2.9 1.9 8.4 0.5 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49_N PF08496.10 KIK66493.1 - 0.087 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HMMR_N PF15905.5 KIK66493.1 - 0.17 11.3 7.6 0.25 10.7 7.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Phage_GP20 PF06810.11 KIK66493.1 - 0.29 10.9 5.5 5.9 6.7 0.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 FAM76 PF16046.5 KIK66493.1 - 0.4 10.0 2.3 0.6 9.4 2.3 1.2 1 0 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 KIK66493.1 - 0.53 10.7 9.5 2.7 8.4 1.6 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain Sec2p PF06428.11 KIK66493.1 - 0.61 10.1 6.2 0.43 10.6 1.3 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 KIK66493.1 - 0.92 8.8 8.6 0.25 10.6 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 KIK66493.1 - 2.2 8.6 6.0 18 5.7 5.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 KIK66493.1 - 4.1 8.0 15.9 0.22 12.0 3.1 2.6 2 1 1 3 3 3 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 KIK66493.1 - 4.7 7.3 11.1 12 6.0 2.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KIK66493.1 - 5.3 7.5 11.6 1e+02 3.4 11.4 2.5 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KIK66493.1 - 5.5 7.7 7.5 2.7 8.7 0.6 2.8 3 0 0 3 3 2 0 Initiation control protein YabA KDZ PF18758.1 KIK66495.1 - 1.2e-21 77.4 3.4 6.3e-17 61.9 1.8 2.4 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK66495.1 - 5.6e-11 42.6 0.5 2.5e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Retrotrans_gag PF03732.17 KIK66496.1 - 2.8e-06 27.5 0.1 1e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein N_NLPC_P60 PF12912.7 KIK66496.1 - 0.21 11.9 0.2 0.21 11.9 0.2 2.4 2 1 0 2 2 2 0 NLPC_P60 stabilising domain, N term RuvA_C PF07499.13 KIK66496.1 - 6.6 7.3 5.3 1.3e+02 3.1 0.2 3.7 4 0 0 4 4 4 0 RuvA, C-terminal domain DpnI_C PF17726.1 KIK66497.1 - 0.038 14.1 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Dam-replacing HTH domain PKcGMP_CC PF16808.5 KIK66498.1 - 0.0069 16.2 5.4 0.96 9.4 0.4 3.9 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK66498.1 - 0.36 11.2 8.6 0.23 11.8 2.7 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF745 PF05335.13 KIK66498.1 - 0.51 10.0 8.8 0.63 9.7 5.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF641 PF04859.12 KIK66498.1 - 1.5 9.2 10.7 0.98 9.8 1.4 3.4 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 KIK66498.1 - 3.3 6.7 9.7 5 6.1 9.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KIK66499.1 - 0.0037 17.1 9.4 0.0069 16.2 9.4 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KIK66499.1 - 0.01 16.3 10.6 0.016 15.6 9.8 1.5 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 KIK66499.1 - 0.011 14.7 9.0 0.017 14.1 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_S49_N PF08496.10 KIK66499.1 - 0.02 15.0 0.3 0.02 15.0 0.3 1.5 2 0 0 2 2 1 0 Peptidase family S49 N-terminal HMMR_N PF15905.5 KIK66499.1 - 0.02 14.4 6.0 0.035 13.6 6.0 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Taxilin PF09728.9 KIK66499.1 - 0.034 13.3 6.0 0.051 12.8 6.0 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein AAA_13 PF13166.6 KIK66499.1 - 0.036 12.7 1.2 0.047 12.3 1.2 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 KIK66499.1 - 0.047 13.5 7.3 1.1 9.0 1.2 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Csm1_N PF18504.1 KIK66499.1 - 0.12 12.7 12.2 0.19 12.1 4.1 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 KIK66499.1 - 0.18 11.7 10.5 1.4 8.9 1.6 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc42p PF11544.8 KIK66499.1 - 0.22 11.5 3.3 4 7.5 0.1 3.1 1 1 1 3 3 3 0 Spindle pole body component Spc42p YabA PF06156.13 KIK66499.1 - 0.26 11.9 3.1 16 6.2 0.2 2.4 2 0 0 2 2 2 0 Initiation control protein YabA LRS4 PF10422.9 KIK66499.1 - 0.3 10.6 5.9 0.55 9.8 5.9 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Atg14 PF10186.9 KIK66499.1 - 0.32 10.0 4.4 0.62 9.1 4.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KIK66499.1 - 0.49 9.7 5.6 0.71 9.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YscO-like PF16789.5 KIK66499.1 - 0.62 10.1 9.6 0.97 9.5 9.6 1.2 1 0 0 1 1 1 0 YscO-like protein DUF4201 PF13870.6 KIK66499.1 - 0.68 9.6 7.4 4.2 7.1 7.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 KIK66499.1 - 0.77 9.8 14.7 1.2 9.2 7.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.11 KIK66499.1 - 0.81 9.7 10.5 0.084 12.9 0.9 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF641 PF04859.12 KIK66499.1 - 1.7 9.0 7.4 3.9 7.8 5.6 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 KIK66499.1 - 2.3 8.3 8.3 0.63 10.1 4.0 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KIK66499.1 - 3.3 7.9 18.1 4.6 7.4 7.5 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Rho_Binding PF08912.11 KIK66499.1 - 3.5 8.5 8.1 3.5 8.5 2.4 2.4 2 0 0 2 2 2 0 Rho Binding Lebercilin PF15619.6 KIK66499.1 - 4.2 7.0 13.1 10 5.7 13.1 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Cnn_1N PF07989.11 KIK66499.1 - 5.1 7.3 8.0 2.8 8.2 0.4 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 KIK66499.1 - 7.3 6.7 11.0 19 5.3 11.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 KIK66499.1 - 8 6.6 10.8 17 5.5 4.2 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Retrotrans_gag PF03732.17 KIK66501.1 - 0.0039 17.4 0.4 5.2 7.4 0.0 3.0 3 1 1 4 4 4 2 Retrotransposon gag protein WD40 PF00400.32 KIK66506.1 - 1.7e-56 186.9 25.8 2.9e-12 46.9 0.6 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66506.1 - 2.9e-25 88.4 0.1 0.0032 17.7 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66506.1 - 7.4e-13 48.1 0.0 0.89 9.6 0.1 5.5 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66506.1 - 5.5e-12 45.3 1.3 0.11 11.5 0.0 5.1 1 1 4 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK66506.1 - 0.0001 22.0 12.7 0.00022 20.9 12.1 2.1 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 KIK66506.1 - 0.0001 21.1 0.6 4.8 5.7 0.0 4.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 KIK66506.1 - 0.00012 20.5 0.0 0.51 8.6 0.0 3.2 1 1 3 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK66506.1 - 0.00034 19.5 0.3 7.8 5.2 0.0 4.3 1 1 4 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1707 PF08044.11 KIK66506.1 - 0.00049 20.1 0.1 47 4.1 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) PQQ_3 PF13570.6 KIK66506.1 - 0.00069 20.0 3.0 9 6.9 0.2 4.4 4 0 0 4 4 4 0 PQQ-like domain Me-amine-dh_H PF06433.11 KIK66506.1 - 0.001 18.0 0.0 0.98 8.2 0.0 2.3 2 1 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 KIK66506.1 - 0.0011 18.8 0.5 45 4.2 0.0 5.0 4 1 1 5 5 5 0 PQQ enzyme repeat WD40_like PF17005.5 KIK66506.1 - 0.0018 17.6 0.0 31 3.8 0.0 4.4 3 1 2 5 5 5 0 WD40-like domain DUF4072 PF13284.6 KIK66506.1 - 0.0021 18.5 4.3 26 5.3 0.0 4.9 6 0 0 6 6 5 0 Domain of unknown function (DUF4072) DPPIV_N PF00930.21 KIK66506.1 - 0.013 14.3 0.0 18 4.0 0.0 4.3 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Phytase-like PF13449.6 KIK66506.1 - 0.056 13.4 0.1 0.66 9.9 0.0 2.4 2 1 0 2 2 2 0 Esterase-like activity of phytase WD40_3 PF15911.5 KIK66506.1 - 0.066 13.2 3.5 59 3.8 0.0 4.8 6 0 0 6 6 5 0 WD domain, G-beta repeat Big_7 PF17957.1 KIK66506.1 - 0.24 12.2 15.1 24 5.8 0.1 5.4 3 2 3 6 6 6 0 Bacterial Ig domain DUF4402 PF14352.6 KIK66506.1 - 0.25 12.0 13.8 0.19 12.4 1.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4402) Proteasome_A_N PF10584.9 KIK66506.1 - 0.59 9.9 7.8 1.1e+02 2.6 0.1 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KIK66507.1 - 1.5e-06 28.2 0.1 3.1e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66507.1 - 2.7e-05 24.6 0.0 3.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66507.1 - 0.00024 21.1 0.2 0.0005 20.0 0.2 1.5 1 1 0 1 1 1 1 NTPase AAA_7 PF12775.7 KIK66507.1 - 0.00065 19.3 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region APS_kinase PF01583.20 KIK66507.1 - 0.00092 19.1 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66507.1 - 0.0032 17.9 0.1 0.0038 17.7 0.1 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66507.1 - 0.0038 16.5 0.1 0.004 16.4 0.1 1.3 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK66507.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK66507.1 - 0.015 15.5 0.1 0.02 15.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK66507.1 - 0.025 14.0 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KIK66507.1 - 0.046 13.0 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KIK66507.1 - 0.046 12.8 0.0 0.087 11.9 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 KIK66507.1 - 0.064 13.3 1.2 0.11 12.5 0.3 1.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KIK66507.1 - 0.066 12.9 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK66507.1 - 0.068 13.7 0.0 0.089 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK66507.1 - 0.079 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK66507.1 - 0.084 13.4 0.0 0.097 13.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KIK66507.1 - 0.11 12.5 0.1 0.12 12.3 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 KIK66507.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase IstB_IS21 PF01695.17 KIK66507.1 - 0.17 11.6 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PIG-U PF06728.13 KIK66508.1 - 0.0044 16.1 0.0 0.0044 16.1 0.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U WD40 PF00400.32 KIK66511.1 - 7.3e-44 146.9 11.0 1.2e-10 41.8 0.4 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66511.1 - 1.3e-15 57.4 0.0 0.0067 16.7 0.0 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66511.1 - 2.4e-10 40.0 0.0 0.54 10.3 0.0 4.5 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66511.1 - 4.9e-10 38.9 1.6 0.063 12.2 0.0 4.0 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KIK66511.1 - 4.9e-06 25.8 1.2 0.047 12.8 0.1 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1513) DPPIV_N PF00930.21 KIK66511.1 - 0.0002 20.3 0.0 0.06 12.1 0.0 2.5 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 KIK66511.1 - 0.00025 20.9 0.9 0.078 12.7 0.4 2.6 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Peptidase_S9_N PF02897.15 KIK66511.1 - 0.00057 18.8 0.5 2.5 6.8 0.0 3.0 1 1 2 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK66511.1 - 0.0012 18.6 3.2 11 6.2 0.0 3.7 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 KIK66511.1 - 0.0017 18.0 3.5 0.0058 16.2 2.7 2.2 1 1 1 2 2 2 1 PQQ-like domain Frtz PF11768.8 KIK66511.1 - 0.0023 16.4 0.0 0.077 11.3 0.0 2.2 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF4072 PF13284.6 KIK66511.1 - 0.0025 18.2 0.3 66 4.1 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) SdrG_C_C PF10425.9 KIK66511.1 - 0.029 14.4 0.0 22 5.1 0.0 2.9 2 1 1 3 3 3 0 C-terminus of bacterial fibrinogen-binding adhesin WD40_3 PF15911.5 KIK66511.1 - 0.039 14.0 0.5 34 4.5 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Nbas_N PF15492.6 KIK66511.1 - 0.1 11.9 0.2 17 4.6 0.0 3.1 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 KIK66511.1 - 0.23 11.2 3.2 67 3.3 0.1 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK66513.1 - 2.3e-144 465.0 70.6 1.7e-11 44.5 0.3 14.1 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66513.1 - 1e-53 179.5 1.3 0.0053 17.0 0.0 13.4 1 1 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK66513.1 - 7.5e-28 97.4 14.9 0.25 10.2 0.0 12.5 3 1 11 14 14 14 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK66513.1 - 3.9e-24 84.0 20.7 3.1 7.9 0.0 13.7 14 0 0 14 14 14 9 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK66513.1 - 2.3e-08 32.8 0.0 5.6 5.1 0.0 7.9 2 2 8 10 10 10 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KIK66513.1 - 6.1e-07 29.1 5.7 3.9 7.6 0.0 9.6 11 0 0 11 11 10 1 PQQ enzyme repeat Nup160 PF11715.8 KIK66513.1 - 3.3e-06 26.0 18.4 1 7.9 0.0 9.9 6 5 6 13 13 13 1 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.11 KIK66513.1 - 6.8e-06 25.2 0.0 0.47 9.3 0.0 5.0 4 2 2 6 6 6 2 Methylamine dehydrogenase heavy chain (MADH) DUF1707 PF08044.11 KIK66513.1 - 2.7e-05 24.2 1.3 66 3.7 0.0 7.9 9 0 0 9 9 9 0 Domain of unknown function (DUF1707) WD40_3 PF15911.5 KIK66513.1 - 0.00026 20.9 3.8 79 3.4 0.0 7.5 9 0 0 9 9 9 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK66513.1 - 0.00033 20.3 39.6 0.061 12.9 6.3 6.5 1 1 4 5 5 5 4 PQQ-like domain DPPIV_N PF00930.21 KIK66513.1 - 0.0013 17.6 0.1 51 2.5 0.0 6.8 1 1 3 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9_N PF02897.15 KIK66513.1 - 0.0022 16.9 1.1 31 3.2 0.0 6.5 2 2 7 9 9 9 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4265 PF14085.6 KIK66513.1 - 0.0031 17.5 6.6 32 4.5 0.0 6.5 6 2 2 8 8 6 0 Domain of unknown function (DUF4265) Phage_attach PF05354.11 KIK66513.1 - 0.0061 16.4 17.0 3 7.8 0.3 7.4 2 1 5 8 8 8 1 Phage Head-Tail Attachment Imm17 PF15562.6 KIK66513.1 - 0.086 12.7 0.6 1.9e+02 2.0 0.0 5.8 6 0 0 6 6 6 0 Immunity protein 17 SLH PF00395.20 KIK66513.1 - 0.11 12.5 0.0 82 3.3 0.0 4.7 4 0 0 4 4 4 0 S-layer homology domain Attacin_N PF03768.15 KIK66513.1 - 1.1 9.4 11.3 6.1 7.0 0.1 6.7 8 1 1 9 9 9 0 Attacin, N-terminal region NACHT PF05729.12 KIK66514.1 - 1.8e-07 31.2 0.0 3.4e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66514.1 - 4.3e-07 30.5 0.0 5.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KIK66514.1 - 0.0002 21.3 0.1 0.00046 20.1 0.1 1.5 1 1 0 2 2 2 1 NTPase APS_kinase PF01583.20 KIK66514.1 - 0.00051 20.0 0.1 0.00087 19.2 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK66514.1 - 0.0021 18.5 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66514.1 - 0.0028 16.9 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK66514.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK66514.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK66514.1 - 0.019 15.1 0.1 0.021 15.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK66514.1 - 0.026 14.6 1.3 0.046 13.8 0.2 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KIK66514.1 - 0.031 13.5 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thymidylate_kin PF02223.17 KIK66514.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 KIK66514.1 - 0.07 12.8 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK66514.1 - 0.077 12.4 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KIK66514.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIK66514.1 - 0.14 12.1 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cytidylate_kin PF02224.18 KIK66514.1 - 0.18 11.5 0.2 0.31 10.7 0.1 1.3 1 1 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 KIK66514.1 - 0.19 10.7 0.1 0.41 9.7 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 KIK66514.1 - 0.22 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FAM76 PF16046.5 KIK66516.1 - 0.013 14.9 0.5 0.013 14.9 0.5 2.1 2 0 0 2 2 2 0 FAM76 protein HMMR_N PF15905.5 KIK66516.1 - 0.022 14.3 2.6 0.038 13.5 2.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK66516.1 - 0.026 13.4 3.3 0.042 12.7 3.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_S49_N PF08496.10 KIK66516.1 - 0.056 13.5 0.1 0.094 12.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PKcGMP_CC PF16808.5 KIK66516.1 - 0.066 13.1 3.8 2.3 8.1 0.4 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MPS2 PF17060.5 KIK66516.1 - 0.067 12.4 0.5 0.11 11.7 0.5 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 bZIP_1 PF00170.21 KIK66516.1 - 0.14 12.3 5.9 5.8 7.1 1.6 2.7 2 0 0 2 2 2 0 bZIP transcription factor LRS4 PF10422.9 KIK66516.1 - 0.63 9.6 4.5 1.1 8.8 4.5 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMF_DNA_bd PF12329.8 KIK66516.1 - 1.6 8.8 8.0 2.2 8.3 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KIK66516.1 - 1.8 9.0 7.2 11 6.4 0.2 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain FMO-like PF00743.19 KIK66518.1 - 6.7e-31 107.3 0.0 5.6e-23 81.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK66518.1 - 5.8e-13 48.8 0.4 2.3e-10 40.2 0.2 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK66518.1 - 4.7e-09 35.9 0.0 9.8e-08 31.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK66518.1 - 1.4e-06 27.8 0.0 1.6e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK66518.1 - 9.4e-05 22.5 0.0 0.0013 18.7 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK66518.1 - 0.00024 21.3 0.0 0.00055 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK66518.1 - 0.0012 18.5 0.3 0.31 10.6 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Velvet PF11754.8 KIK66522.1 - 1.6e-09 38.1 4.5 7.1e-09 36.0 4.5 2.0 1 1 0 1 1 1 1 Velvet factor Herpes_capsid PF06112.11 KIK66522.1 - 7.3 6.6 12.5 10 6.2 12.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein p450 PF00067.22 KIK66524.1 - 2.9e-45 154.9 0.0 5.2e-44 150.8 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.10 KIK66524.1 - 0.059 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DUF1203 PF06718.11 KIK66526.1 - 0.0035 17.6 0.0 0.0048 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) NACHT PF05729.12 KIK66527.1 - 8.1e-10 38.9 0.0 7.6e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66527.1 - 2.6e-05 24.7 0.0 7.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK66527.1 - 0.00053 20.4 0.0 0.019 15.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK66527.1 - 0.0016 18.7 0.0 0.04 14.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KIK66527.1 - 0.0034 16.5 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK66527.1 - 0.014 15.7 0.0 0.045 14.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KIK66527.1 - 0.035 14.1 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.12 KIK66527.1 - 0.078 12.8 0.0 3.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KIK66527.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK66527.1 - 0.17 12.5 0.0 0.41 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK66527.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK66527.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Sugar_tr PF00083.24 KIK66531.1 - 4.4e-84 282.9 12.8 5e-84 282.7 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK66531.1 - 9.8e-26 90.5 32.3 3.7e-17 62.3 13.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK66531.1 - 0.00064 18.3 3.0 0.0011 17.5 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.12 KIK66531.1 - 0.043 13.3 2.5 0.089 12.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF554) IDO PF01231.18 KIK66532.1 - 4.2e-117 391.6 0.0 4.8e-117 391.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Alpha_kinase PF02816.18 KIK66533.1 - 0.015 15.4 0.5 0.039 14.1 0.2 1.7 2 0 0 2 2 2 0 Alpha-kinase family Sugar_tr PF00083.24 KIK66534.1 - 1.3e-82 278.0 23.7 1.6e-82 277.8 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK66534.1 - 7.2e-26 90.9 34.9 2.4e-23 82.6 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK66534.1 - 2.1e-06 26.5 4.1 3.8e-06 25.6 4.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIK66534.1 - 0.00039 19.8 10.3 0.073 12.3 0.6 2.5 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Methyltransf_2 PF00891.18 KIK66536.1 - 2.9e-21 75.7 0.0 8.2e-20 71.0 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KIK66536.1 - 0.00075 20.1 0.0 0.019 15.6 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK66536.1 - 0.0013 18.5 0.0 0.039 13.8 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain HTH_IclR PF09339.10 KIK66536.1 - 0.0089 15.8 0.1 0.025 14.4 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIK66536.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 MarR family Methyltransf_11 PF08241.12 KIK66536.1 - 0.035 14.7 0.0 0.16 12.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MarR PF01047.22 KIK66536.1 - 0.04 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 MarR family MFS_1 PF07690.16 KIK66537.1 - 3.3e-36 124.9 31.7 4.3e-36 124.6 31.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK66537.1 - 2.3e-13 49.8 10.8 7e-13 48.2 10.8 1.8 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK66537.1 - 0.00012 20.7 4.9 0.00022 19.8 4.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIK66537.1 - 0.033 12.5 0.7 0.072 11.4 0.7 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DDE_1 PF03184.19 KIK66539.1 - 1.1e-24 87.1 0.3 2e-24 86.2 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIK66539.1 - 5.4e-06 26.3 0.0 1.8e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AMP-binding PF00501.28 KIK66542.1 - 0.016 13.8 0.1 0.016 13.8 0.1 1.0 1 0 0 1 1 1 0 AMP-binding enzyme AAA_16 PF13191.6 KIK66543.1 - 1.1e-06 29.2 0.0 1.2e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK66543.1 - 2.3e-06 27.7 0.0 5.4e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK66543.1 - 0.0056 16.6 0.0 0.0078 16.1 0.0 1.3 1 1 0 1 1 1 1 NTPase NB-ARC PF00931.22 KIK66543.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KIK66543.1 - 0.015 15.2 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KIK66543.1 - 0.02 15.3 0.0 0.034 14.6 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK66543.1 - 0.064 13.7 0.0 0.22 11.9 0.0 1.8 2 1 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 KIK66543.1 - 0.068 13.1 0.0 0.078 12.9 0.0 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIK66543.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK66543.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KIK66543.1 - 0.17 11.6 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 KIK66544.1 - 1.1e-37 127.3 21.6 4.3e-11 43.2 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66544.1 - 2.2e-13 50.3 0.2 0.62 10.4 0.0 5.7 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66544.1 - 3.1e-09 36.5 1.0 0.56 10.2 0.1 5.5 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66544.1 - 9.4e-09 34.7 4.1 0.21 10.5 0.1 4.9 1 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK66544.1 - 0.00011 21.9 1.3 0.0015 18.2 1.3 2.1 1 1 1 2 2 2 2 PQQ-like domain DUF727 PF05303.12 KIK66544.1 - 0.0019 18.2 0.1 0.78 9.8 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF727) Nbas_N PF15492.6 KIK66544.1 - 0.018 14.4 3.4 7.5 5.8 0.0 4.0 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 KIK66546.1 - 5.8e-05 23.5 0.0 8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK66546.1 - 9.7e-05 22.3 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KIK66546.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 KIK66546.1 - 0.019 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK66546.1 - 0.031 13.5 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KIK66546.1 - 0.22 10.6 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 WD40 PF00400.32 KIK66547.1 - 4.3e-52 172.9 56.0 7.6e-09 36.1 0.1 11.7 11 1 1 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66547.1 - 3.1e-19 69.1 13.2 0.014 15.7 0.1 8.1 1 1 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66547.1 - 7.1e-14 51.3 9.9 0.28 11.2 0.0 8.8 9 0 0 9 9 9 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66547.1 - 7.4e-12 44.9 7.7 0.62 9.0 0.0 7.1 3 2 4 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK66547.1 - 1.4e-07 31.2 8.1 0.15 11.4 0.0 6.0 1 1 4 6 6 6 3 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KIK66547.1 - 1.8e-07 31.1 0.1 0.25 11.4 0.0 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat Frtz PF11768.8 KIK66547.1 - 2.3e-05 22.9 0.6 0.58 8.4 0.0 4.0 2 1 3 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF727 PF05303.12 KIK66547.1 - 3.3e-05 23.9 1.0 18 5.5 0.0 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF727) WD40_like PF17005.5 KIK66547.1 - 0.00022 20.7 2.4 0.17 11.2 0.0 4.2 3 2 0 4 4 4 1 WD40-like domain DUF2244 PF10003.9 KIK66547.1 - 0.028 14.1 1.3 12 5.6 0.0 3.5 4 0 0 4 4 4 0 Integral membrane protein (DUF2244) PI3K_C2 PF00792.24 KIK66547.1 - 0.099 12.6 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 DIPSY PF11763.8 KIK66547.1 - 0.15 12.2 1.4 14 5.9 0.2 3.3 3 1 0 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal Proteasome_A_N PF10584.9 KIK66547.1 - 4.1 7.2 9.5 23 4.8 0.1 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature AMP-binding PF00501.28 KIK66548.1 - 0.00047 18.9 0.1 0.27 9.8 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AAA_16 PF13191.6 KIK66549.1 - 0.0008 19.8 0.0 0.00095 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK66549.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KIK66549.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KIK66549.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KIK66549.1 - 0.043 13.7 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KIK66549.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK66549.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KIK66549.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIF1 PF05970.14 KIK66549.1 - 0.13 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase CbiA PF01656.23 KIK66549.1 - 0.18 11.8 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KIK66549.1 - 0.26 10.5 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.32 KIK66550.1 - 4.3e-40 135.0 51.0 3.6e-10 40.2 0.4 13.4 14 0 0 14 14 14 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66550.1 - 2.6e-20 72.5 5.7 0.53 10.6 0.1 11.3 4 4 8 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66550.1 - 1.8e-10 40.5 16.6 0.033 14.1 0.1 9.6 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66550.1 - 6.5e-10 38.5 5.2 0.43 9.5 0.0 6.6 4 3 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK66550.1 - 6.5e-09 34.6 1.3 0.018 13.4 0.0 5.5 4 2 1 5 5 5 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK66550.1 - 5.8e-08 32.6 7.9 0.0011 18.6 0.1 4.7 3 1 1 4 4 4 2 PQQ-like domain Nbas_N PF15492.6 KIK66550.1 - 1.2e-06 28.1 11.6 1.2 8.4 0.0 8.1 4 4 6 10 10 10 2 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KIK66550.1 - 0.0001 22.2 0.0 0.2 11.7 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF727 PF05303.12 KIK66550.1 - 0.0041 17.2 0.5 2.5 8.2 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF727) 3-dmu-9_3-mt PF06983.13 KIK66550.1 - 0.094 13.3 0.0 12 6.4 0.0 3.5 4 0 0 4 4 4 0 3-demethylubiquinone-9 3-methyltransferase WD40 PF00400.32 KIK66552.1 - 0.00023 21.9 0.1 0.0072 17.2 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat TmoB PF06234.12 KIK66552.1 - 0.075 13.1 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) GST_N_3 PF13417.6 KIK66554.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PIF1 PF05970.14 KIK66555.1 - 3.4e-05 23.2 2.1 0.11 11.7 0.0 3.4 3 2 0 3 3 3 2 PIF1-like helicase PIF1 PF05970.14 KIK66556.1 - 5.2e-16 58.8 0.1 5.2e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 KIK66556.1 - 1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK66556.1 - 2.2e-08 34.5 0.0 4.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK66556.1 - 0.002 18.5 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK66556.1 - 0.056 12.6 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 KIK66556.1 - 0.07 13.1 2.0 0.11 12.5 0.1 2.1 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit Helitron_like_N PF14214.6 KIK66558.1 - 3.5e-21 76.3 0.1 4.4e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inhibitor_I66 PF16850.5 KIK66562.1 - 7.1e-10 38.9 0.0 8.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 CDO_I PF05995.12 KIK66562.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Cysteine dioxygenase type I AMP-binding PF00501.28 KIK66563.1 - 5.3e-91 305.3 0.0 7e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK66563.1 - 0.00019 22.3 0.0 0.00054 20.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Inhibitor_I66 PF16850.5 KIK66563.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I66 DUF2104 PF09877.9 KIK66563.1 - 0.062 13.6 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) Phage_Coat_A PF05357.13 KIK66565.1 - 0.11 12.3 1.1 0.24 11.2 1.1 1.6 1 0 0 1 1 1 0 Phage Coat Protein A DUF908 PF06012.12 KIK66565.1 - 0.19 11.1 3.6 0.24 10.8 3.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Corona_NS2A PF05213.12 KIK66566.1 - 0.019 14.3 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein Multi_ubiq PF14452.6 KIK66566.1 - 0.049 13.9 0.1 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 Multiubiquitin Peptidase_C69 PF03577.15 KIK66566.1 - 0.076 11.9 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C69 Inhibitor_I66 PF16850.5 KIK66567.1 - 5.9e-09 35.9 0.0 6.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 AMP-binding PF00501.28 KIK66568.1 - 1.3e-90 304.0 0.1 1.7e-90 303.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK66568.1 - 0.0004 21.3 0.1 0.0014 19.5 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2104 PF09877.9 KIK66568.1 - 0.068 13.4 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) Ank_4 PF13637.6 KIK66569.1 - 2.8e-05 24.6 0.0 2.2 9.0 0.0 5.8 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK66569.1 - 0.0034 17.7 0.2 36 5.4 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 KIK66569.1 - 0.0099 16.5 0.0 5.6 7.6 0.0 4.0 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) F_actin_cap_B PF01115.17 KIK66574.1 - 4.9e-108 360.2 0.0 5.7e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Lipase_3 PF01764.25 KIK66575.1 - 3.5e-24 85.3 0.1 5.1e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK66575.1 - 0.0024 18.5 1.2 0.0058 17.2 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK66575.1 - 0.0093 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_A4 PF01828.17 KIK66576.1 - 3.5e-74 248.8 19.4 4.7e-74 248.4 19.4 1.2 1 0 0 1 1 1 1 Peptidase A4 family CBM_6 PF03422.15 KIK66576.1 - 0.015 15.6 0.6 0.015 15.6 0.6 2.7 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) CBM_X2 PF03442.14 KIK66576.1 - 0.11 12.6 5.9 0.42 10.8 0.4 3.5 2 1 1 3 3 3 0 Carbohydrate binding domain X2 F-box-like PF12937.7 KIK66577.1 - 1.6e-07 31.1 2.6 5.3e-07 29.4 2.6 2.0 1 0 0 1 1 1 1 F-box-like DivIC PF04977.15 KIK66577.1 - 0.012 15.4 10.9 0.3 10.9 2.8 3.2 2 1 1 3 3 3 0 Septum formation initiator CENP-F_N PF10481.9 KIK66577.1 - 0.1 12.2 8.5 0.21 11.2 7.9 1.7 1 1 1 2 2 2 0 Cenp-F N-terminal domain SOAR PF16533.5 KIK66577.1 - 0.16 12.0 3.7 3.8 7.5 0.5 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region LRR_4 PF12799.7 KIK66577.1 - 0.2 12.1 16.2 13 6.4 0.2 6.3 4 1 3 8 8 8 0 Leucine Rich repeats (2 copies) DUF4200 PF13863.6 KIK66577.1 - 0.46 10.9 9.3 0.14 12.5 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) FliJ PF02050.16 KIK66577.1 - 0.52 10.5 19.0 1.4 9.2 5.6 3.1 1 1 1 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.11 KIK66577.1 - 1.5 9.3 3.1 1e+02 3.4 0.0 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Enkurin PF13864.6 KIK66577.1 - 2.6 8.5 8.6 1.5 9.3 5.3 2.1 1 1 1 2 2 2 0 Calmodulin-binding TMF_TATA_bd PF12325.8 KIK66577.1 - 5.1 7.3 17.1 13 6.0 0.2 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_17 PF00332.18 KIK66578.1 - 2.9e-11 43.6 3.0 1.6e-09 37.8 0.9 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 17 GRA6 PF05084.13 KIK66578.1 - 0.0046 16.9 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Granule antigen protein (GRA6) ETRAMP PF09716.10 KIK66578.1 - 0.009 16.0 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) RhoGAP PF00620.27 KIK66579.1 - 3.6e-37 127.5 0.0 5.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 KIK66579.1 - 0.081 12.1 0.3 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) ORC_WH_C PF18137.1 KIK66579.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.3 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal GMC_oxred_N PF00732.19 KIK66580.1 - 3.6e-70 236.7 0.0 4.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK66580.1 - 1.7e-36 125.9 0.0 3.1e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK66580.1 - 6.5e-05 23.1 0.2 0.00019 21.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK66580.1 - 0.00072 19.2 0.0 0.0032 17.1 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK66580.1 - 0.0028 16.8 0.5 0.014 14.4 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK66580.1 - 0.026 13.6 0.7 0.066 12.3 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KIK66580.1 - 0.063 12.5 0.1 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KIK66580.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Drf_GBD PF06371.13 KIK66581.1 - 4.9e-17 62.1 0.1 5e-12 45.8 0.0 2.6 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain GMC_oxred_N PF00732.19 KIK66582.1 - 5.2e-65 219.7 0.0 6.6e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK66582.1 - 7.5e-38 130.3 0.0 1.4e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK66582.1 - 5.2e-05 23.4 0.1 0.00016 21.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK66582.1 - 0.00015 21.0 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK66582.1 - 0.0002 21.1 0.0 0.0016 18.1 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK66582.1 - 0.00021 20.5 0.2 0.017 14.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIK66582.1 - 0.00066 19.0 0.1 0.0024 17.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK66582.1 - 0.053 12.8 0.1 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK66582.1 - 0.087 11.5 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KIK66582.1 - 0.24 10.6 0.3 0.45 9.7 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DUF1729 PF08354.10 KIK66583.1 - 7.6e-153 508.6 0.0 1.4e-152 507.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 KIK66583.1 - 6.3e-73 244.7 0.1 1.5e-72 243.5 0.1 1.7 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 KIK66583.1 - 6.2e-72 242.8 0.0 3.7e-70 236.9 0.0 3.4 4 0 0 4 4 4 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 KIK66583.1 - 1.2e-71 240.3 0.0 2.3e-71 239.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 KIK66583.1 - 5.7e-44 149.5 0.0 1.6e-43 148.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KIK66583.1 - 4.9e-35 121.4 0.2 1.5e-34 119.8 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 KIK66583.1 - 5.4e-27 94.3 0.8 1.2e-26 93.2 0.8 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KIK66583.1 - 1.1e-25 89.6 0.0 2.8e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 KIK66583.1 - 8.8e-24 84.4 0.2 2.1e-23 83.2 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KIK66583.1 - 5.8e-17 61.9 0.0 1.6e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KIK66583.1 - 1.7e-13 50.6 0.0 4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.6 KIK66583.1 - 6.5e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 KIK66583.1 - 1.2e-08 34.7 0.0 1.3e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66583.1 - 2.7e-05 23.9 0.0 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66583.1 - 0.13 12.2 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 KR domain Kelch_5 PF13854.6 KIK66584.1 - 7.6e-17 60.9 0.3 0.00062 19.7 0.0 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KIK66584.1 - 1.4e-15 57.0 8.6 2.3e-05 24.3 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KIK66584.1 - 1.1e-13 51.1 12.4 0.0035 17.6 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK66584.1 - 6e-11 42.2 4.0 4.9e-05 23.4 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KIK66584.1 - 2.4e-09 36.8 0.3 0.0016 18.3 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KIK66584.1 - 1e-08 34.6 0.2 0.52 10.0 0.0 4.5 4 0 0 4 4 4 3 Kelch motif SKG6 PF08693.10 KIK66584.1 - 0.12 11.9 1.5 0.35 10.3 1.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM199X PF15814.5 KIK66584.1 - 0.13 11.3 0.0 0.13 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein family FAM199X Gram_pos_anchor PF00746.21 KIK66584.1 - 0.31 11.0 1.5 0.79 9.7 1.5 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ACBP PF00887.19 KIK66586.1 - 3.1e-30 104.2 0.7 4.4e-30 103.7 0.7 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 KIK66587.1 - 1.5e-32 112.2 0.3 1.7e-17 63.8 0.2 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KIK66587.1 - 5.1e-12 46.2 11.4 2e-05 25.0 4.4 3.7 2 2 1 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.6 KIK66587.1 - 3.1e-11 43.3 0.1 3.6e-07 30.2 0.1 3.3 3 1 0 3 3 3 2 PH domain PH_8 PF15409.6 KIK66587.1 - 2.2e-08 34.2 0.9 5.4e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KIK66587.1 - 0.0028 18.0 2.2 0.41 11.0 0.6 3.2 2 2 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 KIK66587.1 - 0.015 15.1 0.1 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 KIK66587.1 - 0.14 12.0 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1838 PF08894.11 KIK66587.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1838) Fungal_trans_2 PF11951.8 KIK66588.1 - 2.9e-25 88.9 0.0 3.8e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK66588.1 - 0.0018 18.3 7.6 0.003 17.6 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIK66589.1 - 9.3e-43 146.5 0.1 1.3e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK66589.1 - 3.2e-05 24.0 7.9 5.3e-05 23.2 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VTC PF09359.10 KIK66590.1 - 3.2e-95 318.7 0.8 5.3e-95 317.9 0.0 1.8 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 KIK66590.1 - 2.3e-16 60.7 26.3 8e-10 39.2 11.7 4.1 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 KIK66590.1 - 1.1e-10 41.8 3.2 2.2e-10 40.8 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.16 KIK66590.1 - 0.13 10.7 1.5 0.23 9.9 1.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Piwi PF02171.17 KIK66591.1 - 7.6e-90 301.2 0.0 1.1e-89 300.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK66591.1 - 1.1e-24 87.6 0.0 2.2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIK66591.1 - 1.5e-18 66.2 0.2 9.2e-18 63.7 0.0 2.5 3 0 0 3 3 3 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIK66591.1 - 1.7e-13 50.6 0.1 5.1e-12 45.9 0.0 3.2 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK66591.1 - 1.2e-12 47.9 0.3 2.7e-12 46.8 0.3 1.6 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 KIK66591.1 - 1.6e-06 28.0 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain RNB PF00773.19 KIK66592.1 - 9.1e-49 166.5 0.0 5.8e-48 163.9 0.0 2.2 2 1 0 2 2 2 1 RNB domain BUD22 PF09073.10 KIK66594.1 - 0.0034 16.8 4.4 0.0042 16.5 4.4 1.3 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 KIK66594.1 - 0.013 15.6 7.9 0.02 15.0 7.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Polyoma_lg_T_C PF06431.11 KIK66594.1 - 0.031 13.2 2.4 0.046 12.6 2.4 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CDC45 PF02724.14 KIK66594.1 - 0.1 10.9 6.7 0.13 10.5 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KIK66594.1 - 0.44 9.0 4.7 0.63 8.5 4.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Helitron_like_N PF14214.6 KIK66597.1 - 8.5e-22 78.3 0.0 1.1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIK66599.1 - 0.0054 15.9 0.0 0.0062 15.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF4340 PF14238.6 KIK66606.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) TRP_2 PF08344.11 KIK66609.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Transient receptor ion channel II p450 PF00067.22 KIK66610.1 - 2.4e-68 231.0 0.0 3e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P22_Cro PF14549.6 KIK66611.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Sec7_N PF12783.7 KIK66612.1 - 2.7e-51 173.6 3.8 1.3e-50 171.4 2.2 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KIK66612.1 - 4.8e-51 172.9 5.3 5.7e-51 172.7 1.8 2.7 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KIK66612.1 - 5.7e-36 124.0 0.0 2.8e-20 72.1 0.1 2.5 2 1 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KIK66612.1 - 5e-05 23.1 0.0 0.00034 20.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) BLM10_mid PF16507.5 KIK66612.1 - 0.11 11.1 0.2 0.22 10.1 0.2 1.4 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region HEAT PF02985.22 KIK66612.1 - 2.9 8.4 6.6 15 6.2 0.0 5.3 7 0 0 7 7 7 0 HEAT repeat Ank_4 PF13637.6 KIK66613.1 - 3.2e-27 94.5 0.7 7.2e-09 36.0 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK66613.1 - 6.8e-18 65.0 0.2 1.8e-10 41.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK66613.1 - 8e-15 54.5 0.7 0.00062 20.1 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KIK66613.1 - 1.2e-10 40.7 0.4 0.046 14.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIK66613.1 - 2.1e-10 40.6 0.1 0.0011 19.2 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) GMC_oxred_N PF00732.19 KIK66615.1 - 1.1e-54 185.9 0.1 1.4e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK66615.1 - 1.6e-27 96.8 0.0 3e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK66615.1 - 1.5e-06 27.6 0.4 0.0012 18.1 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK66615.1 - 4.9e-06 26.7 0.4 1.6e-05 25.0 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK66615.1 - 0.0011 18.1 0.2 0.002 17.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK66615.1 - 0.0057 15.9 0.1 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK66615.1 - 0.0064 16.1 0.6 0.014 15.0 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK66615.1 - 0.016 13.9 0.8 0.073 11.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK66615.1 - 0.02 14.2 0.5 0.058 12.6 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MtrD PF04207.12 KIK66615.1 - 0.03 14.0 0.8 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D Thi4 PF01946.17 KIK66615.1 - 0.17 11.1 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Arylsulfotran_2 PF14269.6 KIK66616.1 - 3.3e-56 190.9 2.6 5.3e-56 190.2 2.6 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK66616.1 - 1.4e-10 40.7 1.9 2e-09 36.9 1.9 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 KIK66617.1 - 4.8e-51 173.9 6.6 7.4e-51 173.3 6.6 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIK66617.1 - 9.7e-10 37.9 4.8 1.2e-08 34.2 4.9 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) ig PF00047.25 KIK66617.1 - 0.19 11.9 0.5 0.39 10.9 0.1 1.7 2 0 0 2 2 2 0 Immunoglobulin domain Ank_5 PF13857.6 KIK66618.1 - 0.077 13.3 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) p450 PF00067.22 KIK66619.1 - 1.7e-59 201.8 0.0 4.6e-59 200.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 SPC12 PF06645.13 KIK66619.1 - 0.14 12.2 1.4 5.2 7.2 0.2 3.2 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) p450 PF00067.22 KIK66620.1 - 1.9e-68 231.4 0.0 2.3e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTNNBL PF08216.11 KIK66621.1 - 0.035 14.3 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Gtr1_RagA PF04670.12 KIK66622.1 - 2e-47 161.5 0.1 2.8e-47 161.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK66622.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK66622.1 - 0.0085 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK66622.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KIK66622.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KIK66622.1 - 0.18 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.9 KIK66622.1 - 9.5 4.9 8.3 13 4.5 8.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DAO PF01266.24 KIK66623.1 - 8.8e-31 107.8 0.2 6.8e-30 104.8 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK66623.1 - 0.00035 19.9 0.0 0.0091 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK66623.1 - 0.002 17.3 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK66623.1 - 0.017 15.3 0.2 0.063 13.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIK66623.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK66623.1 - 0.046 13.0 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KIK66623.1 - 0.052 12.2 0.1 0.094 11.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Glu_dehyd_C PF16912.5 KIK66623.1 - 0.061 12.8 0.1 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 KIK66623.1 - 0.11 12.5 0.0 17 5.4 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KIK66623.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KIK66623.1 - 0.2 10.6 0.1 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pro-kuma_activ PF09286.11 KIK66624.1 - 2.3e-30 105.8 0.0 8.1e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain F-box-like PF12937.7 KIK66624.1 - 1.1e-08 34.8 0.2 1.1e-08 34.8 0.2 2.5 3 0 0 3 3 3 1 F-box-like Peptidase_S8 PF00082.22 KIK66624.1 - 8.6e-07 28.5 4.0 1.5e-06 27.7 4.0 1.3 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KIK66625.1 - 1.1e-32 113.2 0.0 1.9e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK66625.1 - 2.2e-08 33.8 1.4 3.6e-08 33.0 1.4 1.3 1 0 0 1 1 1 1 Subtilase family Aldedh PF00171.22 KIK66626.1 - 1.9e-124 415.7 0.0 2.1e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK66626.1 - 5.1e-05 22.5 0.0 7.6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Tlr3_TMD PF17968.1 KIK66627.1 - 0.54 10.5 0.1 0.54 10.5 0.1 3.2 4 0 0 4 4 4 0 Toll-like receptor 3 trans-membrane domain F-box-like PF12937.7 KIK66631.1 - 5.6e-09 35.8 0.8 1.7e-08 34.2 0.8 1.9 1 0 0 1 1 1 1 F-box-like TMF_TATA_bd PF12325.8 KIK66631.1 - 0.048 13.9 0.7 0.11 12.8 0.7 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMEM214 PF10151.9 KIK66631.1 - 0.057 11.9 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator ABC_tran_CTD PF16326.5 KIK66631.1 - 0.098 12.9 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain F-box PF00646.33 KIK66631.1 - 1.1 9.2 4.2 23 5.0 4.2 2.4 1 1 0 1 1 1 0 F-box domain adh_short PF00106.25 KIK66632.1 - 5.2e-24 84.8 0.0 1e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66632.1 - 1.2e-10 41.3 0.0 7.5e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66632.1 - 4.7e-07 29.9 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain CTP_transf_like PF01467.26 KIK66635.1 - 0.18 12.0 0.6 5.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Cytidylyltransferase-like Abhydrolase_3 PF07859.13 KIK66636.1 - 4e-13 49.7 0.0 5.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK66636.1 - 6e-11 41.8 0.0 8.6e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Pro-kuma_activ PF09286.11 KIK66637.1 - 1.5e-31 109.6 0.0 2.6e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK66637.1 - 2.8e-07 30.1 2.8 4.8e-07 29.3 2.8 1.3 1 0 0 1 1 1 1 Subtilase family Fungal_trans PF04082.18 KIK66638.1 - 1.8e-13 50.2 0.1 6.3e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK66638.1 - 0.00042 20.4 12.9 0.00071 19.6 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SLC3A2_N PF16028.5 KIK66638.1 - 0.21 11.2 0.5 0.43 10.2 0.5 1.4 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF5455 PF17537.2 KIK66639.1 - 0.011 16.1 0.3 0.013 15.9 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5455) TFIIA PF03153.13 KIK66640.1 - 0.072 13.1 25.4 0.085 12.8 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 KIK66642.1 - 9.3e-141 453.5 53.3 1e-10 42.0 0.1 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66642.1 - 1.5e-55 185.4 1.7 0.00028 21.1 0.0 13.5 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK66642.1 - 3.7e-16 58.9 6.1 0.17 10.5 0.0 11.6 4 4 9 14 14 14 5 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK66642.1 - 5.7e-16 59.0 0.0 0.027 14.4 0.0 5.8 1 1 6 7 7 7 6 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK66642.1 - 6.8e-15 54.8 1.4 0.5 9.3 0.0 10.1 2 2 8 11 11 11 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK66642.1 - 1.3e-14 54.3 1.2 0.11 11.8 0.1 8.8 5 3 3 9 9 9 4 WD40-like domain PD40 PF07676.12 KIK66642.1 - 1.5e-08 34.4 3.7 8.2 6.5 0.0 7.6 8 0 0 8 8 7 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK66642.1 - 7.5e-08 31.3 3.8 0.017 13.7 0.1 4.8 3 1 0 4 4 4 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 KIK66642.1 - 5.2e-07 29.5 1.6 0.00016 21.3 0.4 3.5 2 1 1 3 3 3 1 PQQ-like domain PQQ_3 PF13570.6 KIK66642.1 - 9.7e-07 29.1 14.8 1.6 9.3 0.0 8.5 6 3 4 10 10 10 1 PQQ-like domain Gmad1 PF10647.9 KIK66642.1 - 1.2e-06 28.5 0.9 1.5 8.5 0.1 6.7 4 2 4 8 8 8 1 Lipoprotein LpqB beta-propeller domain Peptidase_S9_N PF02897.15 KIK66642.1 - 3.9e-06 25.9 6.8 10 4.8 0.1 8.0 3 1 5 9 9 9 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Nucleoporin_N PF08801.11 KIK66642.1 - 9.3e-05 21.3 17.7 0.8 8.4 0.5 7.4 1 1 1 5 5 5 2 Nup133 N terminal like VID27 PF08553.10 KIK66642.1 - 0.00049 19.3 0.2 18 4.3 0.0 4.6 3 1 1 5 5 5 0 VID27 C-terminal WD40-like domain Proteasome_A_N PF10584.9 KIK66642.1 - 0.00095 18.8 10.0 19 5.0 0.0 8.6 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature nos_propeller PF18764.1 KIK66642.1 - 0.003 17.4 11.2 29 4.7 0.1 7.7 9 1 1 10 10 9 0 Nitrous oxide reductase propeller repeat PQQ PF01011.21 KIK66642.1 - 0.0031 17.4 0.0 89 3.3 0.0 6.6 7 0 0 7 7 7 0 PQQ enzyme repeat DUF4072 PF13284.6 KIK66642.1 - 0.0062 16.9 3.2 1.6e+02 2.8 0.0 7.4 10 0 0 10 10 9 0 Domain of unknown function (DUF4072) Gln_amidase PF15644.6 KIK66642.1 - 0.26 12.3 1.7 60 4.7 0.1 3.6 3 1 0 3 3 3 0 Papain fold toxin 1, glutamine deamidase DEAD PF00270.29 KIK66647.1 - 5.5e-36 124.0 0.1 8.8e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK66647.1 - 1.7e-27 95.9 0.5 5.3e-27 94.4 0.2 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KIK66647.1 - 0.042 13.2 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 KIK66647.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK66647.1 - 0.38 11.0 2.1 1.4 9.2 0.9 2.5 2 1 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 KIK66647.1 - 1.8 9.2 5.1 4.2 8.0 5.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DnaJ_C PF01556.18 KIK66648.1 - 9.4e-21 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK66648.1 - 3.4e-18 65.5 0.3 6e-18 64.7 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2263 PF10021.9 KIK66649.1 - 1.6e-20 74.0 0.0 2.5e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KIK66649.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Macro domain DUF2263 PF10021.9 KIK66650.1 - 6.4e-12 46.1 0.0 9.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Malate_DH PF12434.8 KIK66650.1 - 0.22 11.6 0.1 0.4 10.7 0.1 1.3 1 0 0 1 1 1 0 Malate dehydrogenase enzyme DUF2263 PF10021.9 KIK66651.1 - 4.7e-14 53.0 0.0 8.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Sushi_2 PF09014.10 KIK66652.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain DUF2263 PF10021.9 KIK66654.1 - 5.4e-13 49.5 0.0 9.6e-13 48.7 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) fn3_2 PF16893.5 KIK66655.1 - 4.9e-39 132.4 0.4 9e-39 131.5 0.4 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KIK66655.1 - 1.5e-26 92.0 0.1 4.1e-26 90.7 0.1 1.8 2 0 0 2 2 2 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KIK66655.1 - 1.3e-07 31.9 0.0 2.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIK66655.1 - 2.4e-05 24.2 0.1 0.00024 21.0 0.1 2.2 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.21 KIK66655.1 - 0.00088 19.6 0.2 0.0058 17.0 0.4 2.2 2 1 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.8 KIK66655.1 - 0.0029 17.8 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 KIK66655.1 - 0.0093 16.4 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KIK66655.1 - 0.088 12.9 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF4945 PF16303.5 KIK66655.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) NACHT PF05729.12 KIK66656.1 - 0.00015 21.7 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66656.1 - 0.0005 20.5 0.0 0.00066 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK66656.1 - 0.0024 17.8 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK66656.1 - 0.0057 17.0 0.0 0.0084 16.5 0.0 1.4 1 1 0 1 1 1 1 RNA helicase Cytidylate_kin PF02224.18 KIK66656.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_PrkA PF08298.11 KIK66656.1 - 0.023 13.6 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain AAA PF00004.29 KIK66656.1 - 0.041 14.3 0.0 0.056 13.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK66656.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIK66656.1 - 0.093 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KIK66656.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK66656.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein APS_kinase PF01583.20 KIK66656.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 KIK66656.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIK66656.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KIK66656.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KIK66657.1 - 0.0036 17.3 0.1 0.029 14.3 0.0 2.1 1 1 1 2 2 2 1 NACHT domain DUF2235 PF09994.9 KIK66658.1 - 1.4e-77 260.9 0.1 1.8e-77 260.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FliT PF05400.13 KIK66659.1 - 0.14 13.0 2.4 0.22 12.3 2.4 1.3 1 0 0 1 1 1 0 Flagellar protein FliT SUFU PF05076.13 KIK66661.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) MVL PF12151.8 KIK66661.1 - 0.29 11.0 1.1 0.69 9.8 1.1 1.6 1 0 0 1 1 1 0 Mannan-binding protein Adeno_E3_CR2 PF02439.15 KIK66662.1 - 2.6e-06 27.1 0.4 5.2e-06 26.1 0.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1690 PF07956.11 KIK66662.1 - 0.044 14.2 1.4 0.064 13.7 1.4 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) SF1-HH PF16275.5 KIK66662.1 - 0.054 13.8 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF4536 PF15055.6 KIK66662.1 - 0.057 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Spectrin PF00435.21 KIK66662.1 - 0.06 13.8 1.8 0.1 13.1 1.8 1.3 1 0 0 1 1 1 0 Spectrin repeat MVL PF12151.8 KIK66662.1 - 0.13 12.1 0.3 0.36 10.7 0.3 1.7 1 0 0 1 1 1 0 Mannan-binding protein MerR-DNA-bind PF09278.11 KIK66662.1 - 1.3 9.7 6.0 3.2 8.4 0.2 2.3 2 0 0 2 2 2 0 MerR, DNA binding FERM_F2 PF18377.1 KIK66663.1 - 0.029 14.3 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain Pkinase PF00069.25 KIK66664.1 - 2.2e-41 142.0 0.0 1.3e-24 87.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK66664.1 - 5.9e-17 61.8 0.0 6.9e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK66664.1 - 2.9e-05 23.5 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIK66664.1 - 0.0024 17.8 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Arrestin_N PF00339.29 KIK66665.1 - 1.7 8.7 3.1 25 4.9 0.0 2.9 4 0 0 4 4 4 0 Arrestin (or S-antigen), N-terminal domain DUF5336 PF17270.2 KIK66667.1 - 0.04 13.6 0.2 0.042 13.5 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Pro_CA PF00484.19 KIK66668.1 - 3.3e-10 40.5 0.0 1.5e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 Carbonic anhydrase bZIP_2 PF07716.15 KIK66671.1 - 3.3e-08 33.5 2.0 4.7e-08 33.0 2.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK66671.1 - 6.9e-08 32.5 3.2 9.1e-08 32.1 3.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor DNA_pol_A_exo1 PF01612.20 KIK66675.1 - 6.9e-10 38.9 0.1 9.3e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease adh_short PF00106.25 KIK66676.1 - 1.4e-23 83.4 0.0 1.5e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66676.1 - 2.3e-15 56.8 0.0 3.2e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66676.1 - 1.2e-06 28.5 0.1 1.9e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KIK66676.1 - 7e-05 22.4 0.0 0.084 12.3 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK66676.1 - 0.00032 20.2 0.1 0.0023 17.4 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF676 PF05057.14 KIK66677.1 - 2e-39 135.4 0.0 3.5e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KIK66677.1 - 3.9e-08 33.3 0.0 7.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KIK66677.1 - 1.9e-05 24.6 0.0 3.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK66677.1 - 4.1e-05 24.3 0.0 7.5e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KIK66677.1 - 0.0001 22.3 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DLH PF01738.18 KIK66677.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KIK66677.1 - 0.042 13.8 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PUF PF00806.19 KIK66680.1 - 1.8e-28 96.6 0.2 6.1e-08 31.9 0.0 5.3 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Smoothelin PF12510.8 KIK66680.1 - 0.085 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein PSCyt1 PF07635.11 KIK66680.1 - 0.15 12.7 0.0 0.58 10.8 0.0 2.0 1 0 0 1 1 1 0 Planctomycete cytochrome C EthD PF07110.11 KIK66682.1 - 0.065 14.4 0.0 0.13 13.4 0.0 1.5 1 0 0 1 1 1 0 EthD domain Med26 PF08711.11 KIK66684.1 - 1.7e-06 28.0 0.0 4.9e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Glyco_hydro_88 PF07470.13 KIK66685.1 - 6.2e-09 35.4 0.1 1.2e-08 34.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.28 KIK66686.1 - 8.1e-61 205.9 0.0 9.7e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK66686.1 - 5.4e-06 27.3 0.1 1.1e-05 26.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3145 PF11343.8 KIK66688.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3145) Gpr1_Fun34_YaaH PF01184.19 KIK66691.1 - 1.5e-71 240.3 12.8 1.9e-71 240.0 12.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family eIF-5_eIF-2B PF01873.17 KIK66693.1 - 1.3e-39 134.7 0.0 2.4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KIK66693.1 - 5.5e-24 84.1 0.1 5.5e-24 84.1 0.1 2.7 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transf_9 PF04248.12 KIK66694.1 - 3.7e-37 126.1 0.4 1.6e-27 95.2 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF3939 PF13075.6 KIK66694.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) DUF3333 PF11812.8 KIK66696.1 - 0.24 11.6 0.8 6 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Cation_efflux PF01545.21 KIK66701.1 - 5.8e-23 81.7 5.6 7.4e-23 81.3 5.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK66701.1 - 2.1e-10 40.6 0.2 6.5e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF313 PF03754.13 KIK66701.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF313) ZT_dimer PF16916.5 KIK66703.1 - 1.8e-08 34.4 0.0 3.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter His_Phos_2 PF00328.22 KIK66706.1 - 9.7e-50 170.0 0.0 1.2e-49 169.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HMG_box PF00505.19 KIK66707.1 - 7.3e-14 51.9 21.3 2.3e-07 31.1 4.8 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66707.1 - 6e-13 49.2 14.8 1.1e-06 29.2 5.0 2.7 2 1 0 2 2 2 2 HMG-box domain Amidohydro_2 PF04909.14 KIK66707.1 - 0.11 12.3 0.8 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Amidohydrolase DUF1289 PF06945.13 KIK66707.1 - 0.13 12.1 0.2 0.57 10.0 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF3990 PF13151.6 KIK66710.1 - 7.3e-09 35.5 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) F-box-like PF12937.7 KIK66711.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KIK66712.1 - 3.4e-22 78.2 34.9 1.3e-08 35.0 4.3 8.9 6 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK66712.1 - 1.4e-14 53.6 34.5 8.7e-09 35.0 2.9 7.7 6 2 1 7 7 7 5 Leucine rich repeat LRR_1 PF00560.33 KIK66712.1 - 2.1e-08 33.6 22.2 0.85 10.4 0.2 9.9 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KIK66712.1 - 1.7e-07 30.7 28.1 0.6 10.3 2.0 9.4 11 0 0 11 11 11 4 Leucine Rich repeat RNA_GG_bind PF10258.9 KIK66712.1 - 0.84 9.7 2.4 8.7 6.5 0.2 2.4 2 0 0 2 2 2 0 PHAX RNA-binding domain Dsh_C PF12316.8 KIK66714.1 - 0.021 15.2 6.7 0.021 15.2 6.7 4.6 3 1 2 5 5 5 0 Segment polarity protein dishevelled (Dsh) C terminal bVLRF1 PF18826.1 KIK66714.1 - 0.84 9.5 5.8 0.38 10.6 1.8 2.4 2 1 0 2 2 2 0 bacteroidetes VLRF1 release factor INO80_Ies4 PF08193.11 KIK66715.1 - 1.3 9.0 4.8 1.7 8.6 4.2 1.5 1 1 0 1 1 1 0 INO80 complex subunit Ies4 Rho_Binding PF08912.11 KIK66718.1 - 0.038 14.8 0.5 0.08 13.8 0.5 1.5 1 0 0 1 1 1 0 Rho Binding CxC1 PF18802.1 KIK66719.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK66720.1 - 1.8e-64 217.4 2.7 1.8e-64 217.4 2.7 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase zf-CCCH_4 PF18044.1 KIK66721.1 - 6.1e-07 29.1 2.5 1.1e-06 28.2 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Nucleoporin_FG PF13634.6 KIK66721.1 - 1.2e-06 29.2 19.3 1.2e-06 29.2 19.3 6.9 2 1 5 7 7 7 4 Nucleoporin FG repeat region zf_CCCH_4 PF18345.1 KIK66721.1 - 1.6e-05 24.8 4.9 3e-05 23.9 4.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KIK66721.1 - 0.00055 19.8 1.9 0.00092 19.1 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIK66721.1 - 0.2 12.4 0.1 0.34 11.6 0.1 1.3 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KIK66721.1 - 0.73 10.4 3.4 1.6 9.4 3.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FMO-like PF00743.19 KIK66724.1 - 2e-28 99.2 0.0 1.4e-25 89.7 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK66724.1 - 7.5e-13 48.4 0.0 9.9e-11 41.4 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK66724.1 - 1.1e-10 41.7 0.2 0.00011 21.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK66724.1 - 2.3e-08 33.7 0.0 0.0045 16.2 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK66724.1 - 6.3e-07 29.5 0.0 2.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIK66724.1 - 7.9e-06 25.2 0.0 0.0041 16.3 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK66724.1 - 0.00012 22.5 0.0 0.039 14.5 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK66724.1 - 0.00033 20.8 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIK66724.1 - 0.00051 20.4 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KIK66724.1 - 0.00062 19.3 0.1 0.0054 16.2 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KIK66724.1 - 0.0061 16.6 0.0 1.4 9.0 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KIK66724.1 - 0.02 14.2 0.0 1.2 8.3 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase HMG_box PF00505.19 KIK66725.1 - 3.1e-14 53.2 2.4 5.4e-14 52.4 2.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66725.1 - 1.1e-09 38.7 1.2 2.2e-09 37.8 1.2 1.5 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 KIK66726.1 - 2.3e-45 155.1 0.0 2.7e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK66726.1 - 2.1e-10 41.0 0.2 6.8e-06 26.5 0.7 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK66726.1 - 1e-05 24.8 0.0 0.08 12.0 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 KIK66726.1 - 0.00078 18.8 0.5 0.34 10.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK66726.1 - 0.011 14.8 0.0 0.26 10.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK66726.1 - 0.012 15.9 0.0 0.84 9.9 0.0 3.0 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK66726.1 - 0.084 12.1 0.3 2.3 7.4 0.2 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DFRP_C PF16543.5 KIK66727.1 - 9.3e-28 96.6 4.7 9.3e-28 96.6 4.7 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KIK66727.1 - 1.7e-06 28.7 10.4 3.2e-05 24.6 4.6 3.1 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KIK66727.1 - 3.5e-05 23.5 8.9 0.00011 21.8 2.0 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIK66727.1 - 7.5e-05 22.6 6.1 7.5e-05 22.6 6.1 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 KIK66727.1 - 0.00011 22.0 0.9 0.00011 22.0 0.9 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ndc1_Nup PF09531.10 KIK66727.1 - 0.064 12.0 1.8 0.08 11.6 1.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CCCH_2 PF14608.6 KIK66727.1 - 2.6 8.7 12.6 0.83 10.2 4.9 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nucleo_P87 PF07267.11 KIK66727.1 - 4.5 6.0 18.2 0.11 11.3 1.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-CCCH_3 PF15663.5 KIK66727.1 - 4.6 7.5 10.4 0.21 11.8 1.0 2.8 2 1 1 3 3 3 0 Zinc-finger containing family KBP_C PF12309.8 KIK66727.1 - 6.7 6.1 14.1 0.086 12.4 6.1 1.7 2 0 0 2 2 2 0 KIF-1 binding protein C terminal F-box-like_2 PF13013.6 KIK66728.1 - 0.0074 16.2 0.2 0.015 15.3 0.2 1.4 1 0 0 1 1 1 1 F-box-like domain adh_short PF00106.25 KIK66729.1 - 6.6e-25 87.7 0.0 9.2e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66729.1 - 2.2e-14 53.6 0.0 6.9e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66729.1 - 3.5e-09 36.8 0.1 9.8e-09 35.4 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66729.1 - 3.4e-06 26.4 0.0 7.6e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK66729.1 - 0.0039 16.7 0.1 0.011 15.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK66729.1 - 0.035 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK66730.1 - 5.6e-24 84.7 0.0 7.7e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66730.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66730.1 - 9.7e-10 38.6 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66730.1 - 9.5e-08 31.5 0.0 1.6e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 KIK66730.1 - 0.0018 18.8 0.2 0.0039 17.7 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KIK66730.1 - 0.0019 17.7 0.7 0.01 15.3 0.7 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK66730.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pyr_redox_2 PF07992.14 KIK66730.1 - 0.023 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KIK66730.1 - 0.028 14.7 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KIK66730.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_7 PF13241.6 KIK66730.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 KIK66731.1 - 1.5e-25 89.9 0.0 1.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66731.1 - 2.7e-18 66.4 0.0 3.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66731.1 - 3.8e-11 43.2 0.0 5.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66731.1 - 2.9e-07 29.9 0.0 8.6e-06 25.1 0.0 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK66731.1 - 0.00056 19.4 0.1 0.0032 17.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK66731.1 - 0.011 15.1 0.0 0.14 11.6 0.0 2.3 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 KIK66731.1 - 0.025 15.1 1.2 0.062 13.9 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK66731.1 - 0.042 13.1 0.0 0.083 12.1 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KIK66732.1 - 7.3e-27 94.1 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66732.1 - 7.2e-16 58.4 0.0 9.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66732.1 - 2.1e-10 40.8 0.0 3.2e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66732.1 - 6.2e-07 28.8 0.0 1.3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK66732.1 - 0.00056 19.4 0.1 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 KIK66732.1 - 0.0034 17.9 0.1 0.0094 16.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KIK66732.1 - 0.0069 15.9 0.1 0.15 11.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KIK66732.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KIK66732.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KIK66733.1 - 9.1e-23 80.7 0.0 1.4e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66733.1 - 1.2e-13 51.1 0.0 2.1e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KIK66733.1 - 1.3e-08 34.4 0.0 8.1e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.10 KIK66733.1 - 4.5e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KIK66733.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK66733.1 - 0.029 13.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIK66733.1 - 0.033 14.8 0.2 0.09 13.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK66733.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KIK66735.1 - 9.6e-14 51.3 0.0 7.8e-13 48.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66735.1 - 2.8e-13 50.0 0.0 1.9e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK66736.1 - 1.6e-26 93.0 0.0 2.3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66736.1 - 8.7e-16 58.2 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66736.1 - 1.1e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66736.1 - 6.9e-07 28.7 0.0 5.5e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK66736.1 - 0.00075 19.0 0.1 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 KIK66736.1 - 0.0054 17.3 0.1 0.015 15.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KIK66736.1 - 0.0074 15.8 0.1 0.083 12.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KIK66736.1 - 0.023 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KIK66737.1 - 9.6e-25 87.2 0.0 1.4e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66737.1 - 4.2e-16 59.2 0.0 5.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66737.1 - 1.4e-09 38.1 0.0 1.8e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66737.1 - 3.7e-09 36.1 0.0 4.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 KIK66737.1 - 0.014 15.9 0.1 0.11 13.1 0.3 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KIK66737.1 - 0.015 14.8 0.2 2.3 7.6 0.1 2.4 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK66737.1 - 0.015 14.7 0.1 0.032 13.6 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK66738.1 - 1.6e-28 99.5 0.1 2.1e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66738.1 - 9.9e-20 71.1 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66738.1 - 2.5e-08 34.0 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66738.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 KIK66738.1 - 0.069 13.1 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Clathrin_bdg PF15045.6 KIK66738.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking adh_short PF00106.25 KIK66739.1 - 1.5e-28 99.6 0.0 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66739.1 - 1.5e-18 67.2 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66739.1 - 2.4e-07 30.8 0.0 4.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66739.1 - 0.0052 16.0 0.0 0.0076 15.4 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Clathrin_bdg PF15045.6 KIK66739.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking MreD PF04093.12 KIK66740.1 - 7.5 6.6 14.6 0.16 12.0 0.5 2.9 2 1 1 3 3 3 0 rod shape-determining protein MreD SLATT_5 PF18160.1 KIK66740.1 - 9.3 5.5 9.6 4.4 6.6 3.2 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 COX7C PF02935.16 KIK66742.1 - 7e-09 35.8 0.4 7.8e-09 35.7 0.4 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DNA_pol_A_exo1 PF01612.20 KIK66744.1 - 3.7e-16 59.3 0.1 5.4e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Cellulase PF00150.18 KIK66747.1 - 8.6e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rx_N PF18052.1 KIK66748.1 - 0.42 10.9 2.7 12 6.3 2.3 2.7 1 1 0 1 1 1 0 Rx N-terminal domain DUF4061 PF13270.6 KIK66748.1 - 0.57 10.5 4.0 5.8 7.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DegS PF05384.11 KIK66748.1 - 1.9 8.0 6.9 29 4.1 7.0 2.3 1 1 1 2 2 2 0 Sensor protein DegS PTP_tm PF18861.1 KIK66749.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J zf-C2H2_8 PF15909.5 KIK66750.1 - 5.5e-05 23.4 0.8 0.00012 22.3 0.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KIK66750.1 - 0.00029 21.1 2.4 0.27 11.8 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK66750.1 - 0.00072 20.2 4.7 0.36 11.8 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DM PF00751.18 KIK66750.1 - 0.2 11.6 1.2 0.37 10.7 1.2 1.5 1 0 0 1 1 1 0 DM DNA binding domain zf-C2H2 PF00096.26 KIK66753.1 - 1.4e-08 34.7 4.8 0.00017 21.9 0.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK66753.1 - 2.1e-07 31.2 4.5 0.0009 19.9 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK66753.1 - 5.2e-05 23.5 0.9 5.2e-05 23.5 0.9 1.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KIK66753.1 - 0.0008 19.7 1.3 0.0063 16.9 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KIK66753.1 - 0.00095 18.9 2.8 0.0035 17.1 0.1 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type FOXP-CC PF16159.5 KIK66753.1 - 0.013 16.1 0.1 0.017 15.7 0.1 1.2 1 0 0 1 1 1 0 FOXP coiled-coil domain IBR PF01485.21 KIK66753.1 - 0.015 15.5 0.3 0.019 15.2 0.3 1.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain LIM PF00412.22 KIK66753.1 - 0.05 13.8 1.8 0.12 12.7 1.6 1.7 1 1 1 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.10 KIK66753.1 - 0.13 12.4 2.3 0.35 11.0 0.1 2.2 2 1 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 KIK66753.1 - 0.14 12.3 3.2 3.3 8.0 2.8 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_jaz PF12171.8 KIK66753.1 - 0.19 12.1 7.2 0.71 10.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIK66754.1 - 9.7e-06 25.8 6.0 0.00027 21.2 2.2 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK66754.1 - 2.7e-05 24.4 12.0 0.00037 20.8 3.2 2.5 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK66754.1 - 0.00021 21.8 10.7 0.0045 17.7 2.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger Elf1 PF05129.13 KIK66754.1 - 0.0062 16.6 1.8 0.076 13.1 2.3 1.9 1 1 1 2 2 2 2 Transcription elongation factor Elf1 like Ephrin_rec_like PF07699.13 KIK66754.1 - 0.007 16.1 2.3 0.03 14.1 1.4 2.0 2 0 0 2 2 2 1 Putative ephrin-receptor like HypA PF01155.19 KIK66754.1 - 0.009 16.0 1.0 0.011 15.7 1.0 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KIK66754.1 - 0.011 15.8 4.0 0.023 14.8 1.7 2.3 1 1 1 2 2 2 0 Zinc ribbon domain CpXC PF14353.6 KIK66754.1 - 0.012 15.6 1.9 0.098 12.7 0.1 2.0 1 1 1 2 2 2 0 CpXC protein DZR PF12773.7 KIK66754.1 - 0.016 15.2 1.9 0.023 14.7 1.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.6 KIK66754.1 - 0.02 14.9 9.9 0.95 9.5 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KIK66754.1 - 0.026 15.3 1.2 0.034 14.9 1.2 1.2 1 0 0 1 1 1 0 zinc-ribbon family DUF2256 PF10013.9 KIK66754.1 - 0.027 14.6 0.8 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.6 KIK66754.1 - 0.031 14.8 6.6 1 9.9 0.4 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 KIK66754.1 - 0.039 13.5 1.6 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 KIK66754.1 - 0.041 13.8 3.5 3.6 7.6 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KIK66754.1 - 0.05 13.4 3.4 0.75 9.6 0.8 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type RNA_POL_M_15KD PF02150.16 KIK66754.1 - 0.063 13.2 0.9 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KIK66754.1 - 0.074 13.4 1.6 0.13 12.6 1.6 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar FYVE PF01363.21 KIK66754.1 - 0.081 13.1 5.9 0.12 12.5 5.9 1.3 1 0 0 1 1 1 0 FYVE zinc finger zf-FPG_IleRS PF06827.14 KIK66754.1 - 0.16 11.9 3.7 2.1 8.3 1.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS TFIIS_C PF01096.18 KIK66754.1 - 0.17 11.8 3.4 8.4 6.3 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Rubredoxin_2 PF18073.1 KIK66754.1 - 0.39 10.5 3.0 13 5.7 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-AN1 PF01428.16 KIK66754.1 - 0.53 10.5 8.6 0.7 10.1 1.5 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger OrfB_Zn_ribbon PF07282.11 KIK66754.1 - 0.57 10.2 5.1 6.1 6.8 0.3 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C2HC_2 PF13913.6 KIK66754.1 - 2.8 7.9 10.5 15 5.6 3.6 3.1 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Zn_clus PF00172.18 KIK66755.1 - 6e-06 26.3 6.1 6e-06 26.3 6.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KIK66755.1 - 0.00093 19.5 1.4 0.00093 19.5 1.4 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK66755.1 - 0.056 13.9 8.4 0.18 12.3 2.6 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK66755.1 - 0.087 13.7 0.9 0.087 13.7 0.9 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger AMP-binding PF00501.28 KIK66757.1 - 1.2e-64 218.5 0.0 1.4e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK66757.1 - 3.6e-06 27.8 0.0 7.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_43 PF04616.14 KIK66761.1 - 4.6e-36 124.6 0.1 6e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2673 PF10880.8 KIK66761.1 - 0.099 12.8 0.6 0.27 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) adh_short PF00106.25 KIK66762.1 - 2.8e-26 92.2 0.1 3.5e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66762.1 - 2.2e-17 63.4 0.0 3e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66762.1 - 1.2e-10 41.6 0.1 1.9e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66762.1 - 2.1e-05 23.8 0.1 4e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK66762.1 - 0.0088 15.5 0.1 0.14 11.6 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK66762.1 - 0.071 12.5 0.1 0.13 11.7 0.1 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK66764.1 - 2.7e-27 95.5 0.0 3.6e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK66764.1 - 6.8e-17 61.8 0.0 9.3e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK66764.1 - 1.2e-10 41.6 0.0 1.6e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK66764.1 - 7.3e-07 28.6 0.0 2.2e-06 27.0 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK66764.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK66764.1 - 0.0072 15.8 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIK66764.1 - 0.011 16.2 0.2 0.033 14.7 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK66764.1 - 0.063 12.5 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF5310 PF17237.2 KIK66765.1 - 0.043 13.7 0.5 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5310) DUF1122 PF06557.11 KIK66765.1 - 0.091 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) DUF4633 PF15464.6 KIK66766.1 - 4.9 7.3 7.5 21 5.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) DUF872 PF05915.12 KIK66767.1 - 0.063 13.4 0.4 0.12 12.6 0.2 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF2721 PF11026.8 KIK66767.1 - 0.49 10.3 5.8 0.91 9.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CbtB PF09489.10 KIK66767.1 - 9.1 6.5 8.1 1.3 9.2 0.2 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) FAD_binding_3 PF01494.19 KIK66771.1 - 4.8e-17 62.2 0.0 6.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK66771.1 - 0.00024 21.2 0.6 0.00057 20.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK66771.1 - 0.0011 18.6 0.2 0.0029 17.2 0.1 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK66771.1 - 0.0013 18.1 1.1 0.014 14.6 0.4 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK66771.1 - 0.014 14.1 0.4 2.6 6.7 0.9 2.2 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 KIK66771.1 - 0.049 12.7 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 KIK66771.1 - 0.052 12.4 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KIK66771.1 - 0.19 12.3 1.9 1 10.0 2.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase gag_pre-integrs PF13976.6 KIK66772.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-AD PF07776.15 KIK66772.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) FAD_binding_3 PF01494.19 KIK66775.1 - 5.2e-18 65.4 0.0 1.1e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK66775.1 - 0.0016 18.6 0.5 0.0037 17.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK66775.1 - 0.0057 15.9 0.0 0.054 12.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIK66775.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.3 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.19 KIK66776.1 - 1.8e-20 73.5 0.0 2.5e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK66776.1 - 0.0011 19.1 0.5 0.0024 18.1 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK66776.1 - 0.0012 18.1 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK66776.1 - 0.0026 16.7 0.2 0.041 12.7 0.1 2.3 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KIK66776.1 - 0.17 11.9 0.1 9.5 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK66776.1 - 0.26 10.5 0.9 21 4.2 0.9 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N PF02798.20 KIK66777.1 - 1.4e-11 44.6 0.1 4.9e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK66777.1 - 7.6e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK66777.1 - 9.2e-09 35.6 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK66777.1 - 1.4e-07 31.7 0.2 3.7e-07 30.3 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK66777.1 - 0.00046 20.2 0.0 0.00087 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK66777.1 - 0.0006 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF5054 PF16477.5 KIK66777.1 - 0.022 14.6 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) Tom37 PF10568.9 KIK66777.1 - 0.075 13.4 0.1 0.19 12.0 0.0 1.7 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein Aa_trans PF01490.18 KIK66778.1 - 2.6e-83 280.0 30.2 3e-83 279.8 30.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bac_rhamnosid6H PF17389.2 KIK66779.1 - 1.3e-12 47.7 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KIK66779.1 - 7e-07 28.4 0.2 1e-06 27.9 0.2 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 KIK66779.1 - 3.1e-06 26.9 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 KIK66779.1 - 0.0037 17.2 0.0 0.0094 15.9 0.0 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain GDE_C PF06202.14 KIK66779.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Glyco_hydro_36 PF17167.4 KIK66779.1 - 0.14 10.8 0.2 0.22 10.2 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Corona_M PF01635.18 KIK66780.1 - 0.033 13.5 0.2 0.056 12.7 0.2 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein WD40 PF00400.32 KIK66781.1 - 4.6e-117 378.6 53.6 1.5e-10 41.5 0.1 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66781.1 - 3.3e-45 152.3 4.7 0.0043 17.3 0.0 12.9 1 1 12 13 13 13 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66781.1 - 1.5e-21 75.7 14.8 0.93 9.5 0.0 11.8 12 0 0 12 12 12 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66781.1 - 5.6e-15 55.1 0.1 0.4 9.6 0.0 9.2 7 3 2 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK66781.1 - 1.5e-09 37.7 0.0 1.2 8.4 0.0 7.2 8 2 2 10 10 10 3 WD40-like domain DUF4265 PF14085.6 KIK66781.1 - 6.4e-08 32.6 3.9 19 5.2 0.0 7.9 8 1 1 9 9 9 0 Domain of unknown function (DUF4265) Nup160 PF11715.8 KIK66781.1 - 8.5e-08 31.3 0.2 5.5 5.5 0.0 8.3 9 2 1 11 11 11 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK66781.1 - 1.1e-06 28.9 18.2 0.37 11.3 0.0 10.1 6 4 3 9 9 9 1 PQQ-like domain PQQ_2 PF13360.6 KIK66781.1 - 1.3e-05 24.9 17.7 1.3 8.6 11.2 5.0 1 1 1 2 2 2 2 PQQ-like domain Proteasome_A_N PF10584.9 KIK66781.1 - 7.5e-05 22.3 21.6 26 4.6 0.0 10.3 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature PQQ PF01011.21 KIK66781.1 - 0.0013 18.5 0.4 1.8 8.6 0.1 5.6 7 0 0 7 7 5 1 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK66781.1 - 0.0015 17.1 0.0 2 6.8 0.0 4.0 4 1 1 5 5 5 1 Cytochrome D1 heme domain DUF4784 PF16023.5 KIK66781.1 - 0.0018 17.3 0.0 68 2.2 0.0 5.5 3 1 2 6 6 6 0 Domain of unknown function (DUF4784) Frtz PF11768.8 KIK66781.1 - 0.0041 15.5 0.0 11 4.3 0.0 5.0 7 2 0 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz Me-amine-dh_H PF06433.11 KIK66781.1 - 0.034 13.0 0.0 12 4.6 0.0 4.5 4 2 4 8 8 8 0 Methylamine dehydrogenase heavy chain (MADH) 5-FTHF_cyc-lig PF01812.20 KIK66781.1 - 0.24 11.2 3.1 55 3.5 0.0 5.5 7 1 0 8 8 8 0 5-formyltetrahydrofolate cyclo-ligase family AAA_16 PF13191.6 KIK66782.1 - 1.8e-07 31.7 0.0 2.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK66782.1 - 1.4e-05 25.1 0.0 1.6e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KIK66782.1 - 2.4e-05 24.3 0.0 4.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK66782.1 - 0.00012 22.4 0.0 0.00016 22.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK66782.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK66782.1 - 0.0002 20.6 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PIF1 PF05970.14 KIK66782.1 - 0.00067 18.9 0.0 0.0012 18.1 0.0 1.4 2 0 0 2 2 2 1 PIF1-like helicase RNA_helicase PF00910.22 KIK66782.1 - 0.0016 18.8 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KIK66782.1 - 0.0024 17.4 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KIK66782.1 - 0.0035 17.3 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.27 KIK66782.1 - 0.0036 17.8 0.1 0.0047 17.4 0.1 1.3 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 KIK66782.1 - 0.0048 17.3 0.1 0.013 16.0 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK66782.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK66782.1 - 0.012 16.1 0.5 0.096 13.2 0.3 2.0 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK66782.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 KIK66782.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 KaiC Viral_helicase1 PF01443.18 KIK66782.1 - 0.016 14.9 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KIK66782.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 KIK66782.1 - 0.032 14.0 0.2 0.047 13.5 0.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KIK66782.1 - 0.038 13.9 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 KIK66782.1 - 0.04 13.2 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 KIK66782.1 - 0.047 13.4 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase APS_kinase PF01583.20 KIK66782.1 - 0.047 13.6 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 KIK66782.1 - 0.052 13.3 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 KIK66782.1 - 0.081 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KIK66782.1 - 0.088 13.0 0.2 0.11 12.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIK66782.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF87 PF01935.17 KIK66782.1 - 0.13 12.4 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 KIK66782.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIK66782.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Herpes_Helicase PF02689.14 KIK66782.1 - 0.2 9.5 0.0 0.2 9.5 0.0 1.1 1 0 0 1 1 1 0 Helicase Bac_rhamnosid6H PF17389.2 KIK66783.1 - 5.4e-17 62.0 0.0 8.3e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KIK66783.1 - 6.4e-06 25.3 0.1 9.9e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 KIK66783.1 - 3.3e-05 23.6 0.0 6.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 KIK66783.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain GDE_C PF06202.14 KIK66783.1 - 0.026 13.5 0.5 0.05 12.5 0.5 1.4 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF608 PF04685.13 KIK66783.1 - 0.028 13.6 0.1 0.049 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Methyltransf_23 PF13489.6 KIK66784.1 - 1.2e-10 41.5 0.0 3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66784.1 - 9.4e-09 35.9 0.0 1.6e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK66784.1 - 1.2e-05 24.8 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIK66784.1 - 0.00017 22.2 0.0 0.00026 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK66784.1 - 0.039 14.7 0.0 0.093 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 KIK66786.1 - 2.4e-05 23.9 0.2 0.055 12.9 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK66786.1 - 0.00019 21.4 0.2 0.00076 19.4 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK66786.1 - 0.00071 18.7 0.3 0.0015 17.6 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK66786.1 - 0.0021 17.3 0.2 0.016 14.4 0.1 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KIK66786.1 - 0.0038 16.8 0.2 0.0058 16.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIK66786.1 - 0.005 16.3 0.2 0.035 13.5 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KIK66786.1 - 0.037 13.9 0.1 0.094 12.6 0.1 1.6 1 1 1 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 KIK66786.1 - 0.047 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-C2H2 PF00096.26 KIK66788.1 - 5.8e-13 48.5 14.5 2.8e-05 24.3 0.4 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK66788.1 - 1.3e-08 34.9 14.1 0.0059 17.3 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK66788.1 - 2.7e-07 30.7 18.8 0.00048 20.4 0.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KIK66788.1 - 0.0036 17.5 3.5 0.95 9.6 0.1 2.9 1 1 2 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 KIK66788.1 - 0.0041 17.5 4.9 1.7 9.2 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KIK66788.1 - 0.0044 17.3 5.2 0.027 14.8 4.1 2.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIK66788.1 - 0.0053 17.0 6.8 1.5 9.2 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK66788.1 - 0.012 15.6 1.9 3 7.9 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK66788.1 - 0.035 14.7 8.4 0.77 10.4 3.3 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain LIM PF00412.22 KIK66788.1 - 0.98 9.7 8.1 0.44 10.8 5.6 1.7 1 1 1 2 2 2 0 LIM domain Acetyltransf_3 PF13302.7 KIK66789.1 - 8.4e-16 58.9 0.0 1.2e-15 58.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK66790.1 - 1.1e-17 65.0 0.0 1.6e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.26 KIK66794.1 - 0.0001 22.6 3.0 0.022 15.2 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK66794.1 - 0.00023 21.7 1.0 0.23 12.4 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIK66794.1 - 0.015 15.7 0.0 2.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Cytochrom_NNT PF03264.14 KIK66794.1 - 0.022 14.5 0.3 0.035 13.8 0.3 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region zf-C2H2_3rep PF18868.1 KIK66794.1 - 0.033 14.9 0.0 0.069 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats TPR_10 PF13374.6 KIK66796.1 - 1.6e-62 205.8 27.6 2.8e-09 36.5 0.2 13.5 13 1 0 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 KIK66796.1 - 1.5e-60 201.4 20.3 1.4e-10 41.3 0.0 9.1 4 4 6 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.28 KIK66796.1 - 3.4e-18 64.6 19.8 0.26 11.2 0.2 11.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK66796.1 - 1.1e-16 59.5 20.9 0.081 13.0 0.2 11.6 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK66796.1 - 1.3e-14 53.0 25.1 0.11 12.6 0.4 11.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIK66796.1 - 4.4e-09 36.1 0.1 0.57 11.0 0.0 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat NB-ARC PF00931.22 KIK66796.1 - 9.3e-09 34.8 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 KIK66796.1 - 3.7e-08 33.0 21.0 0.59 10.5 0.1 10.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK66796.1 - 2.9e-07 30.9 11.8 3.4 8.3 0.1 8.1 3 1 7 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK66796.1 - 1.7e-06 28.4 7.6 3.8 8.6 0.0 7.5 9 0 0 9 9 5 1 Tetratricopeptide repeat TPR_5 PF12688.7 KIK66796.1 - 3.5e-06 27.3 4.4 0.3 11.3 0.0 5.9 3 2 2 6 6 6 1 Tetratrico peptide repeat TPR_16 PF13432.6 KIK66796.1 - 3.7e-06 27.5 14.3 0.28 11.9 0.1 8.8 10 1 0 10 10 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK66796.1 - 4e-06 27.0 5.2 1.7 8.9 0.0 6.5 1 1 7 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KIK66796.1 - 6.3e-06 25.8 4.8 0.0025 17.3 0.1 4.0 1 1 1 4 4 4 1 MalT-like TPR region SRP_TPR_like PF17004.5 KIK66796.1 - 8.9e-06 25.7 0.4 1.2 9.2 0.3 5.6 3 2 2 5 5 5 1 Putative TPR-like repeat Fis1_TPR_C PF14853.6 KIK66796.1 - 1.9e-05 24.6 9.2 0.067 13.3 0.1 6.4 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KIK66796.1 - 7.8e-05 22.6 1.0 12 6.0 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Paf67 PF10255.9 KIK66796.1 - 0.00013 21.1 0.2 1.3 7.9 0.0 4.2 3 2 1 4 4 4 2 RNA polymerase I-associated factor PAF67 TPR_6 PF13174.6 KIK66796.1 - 0.0012 19.4 5.1 1.3 9.9 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat SPOB_a PF14689.6 KIK66796.1 - 0.0012 18.5 1.2 0.89 9.3 0.1 3.9 4 0 0 4 4 4 1 Sensor_kinase_SpoOB-type, alpha-helical domain ResIII PF04851.15 KIK66796.1 - 0.0085 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_9 PF13371.6 KIK66796.1 - 0.011 15.9 6.4 4.2 7.6 0.1 5.9 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK66796.1 - 0.023 15.1 16.5 47 4.7 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat MgsA_C PF12002.8 KIK66796.1 - 0.068 13.1 0.0 4.9 7.1 0.0 3.1 2 1 1 3 3 3 0 MgsA AAA+ ATPase C terminal CbiA PF01656.23 KIK66796.1 - 0.12 12.4 0.0 0.64 10.1 0.0 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Homeodomain PF00046.29 KIK66799.1 - 0.0056 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain AGS_C PF18134.1 KIK66799.1 - 0.046 13.7 0.2 0.09 12.8 0.2 1.4 1 0 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain HMG_box PF00505.19 KIK66800.1 - 6.4e-17 61.7 0.2 7.9e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66800.1 - 7.2e-08 32.9 0.1 9.9e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KIK66803.1 - 1.3e-15 57.6 0.2 1.4e-15 57.4 0.2 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66803.1 - 2.7e-06 27.9 0.1 3e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KIK66804.1 - 4.7e-15 55.8 1.3 1.1e-14 54.6 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66804.1 - 2.3e-07 31.3 0.1 4.7e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain SLATT_5 PF18160.1 KIK66805.1 - 6.5 6.0 8.9 1.2 8.4 0.3 2.8 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 HTH_Tnp_Tc5 PF03221.16 KIK66806.1 - 1.7e-06 28.0 0.5 4.3e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Amidohydro_2 PF04909.14 KIK66809.1 - 1.8e-43 149.4 0.5 2.1e-43 149.2 0.5 1.0 1 0 0 1 1 1 1 Amidohydrolase Amino_oxidase PF01593.24 KIK66810.1 - 1.4e-49 169.7 0.0 1.9e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK66810.1 - 6e-14 52.0 0.0 1.5e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK66810.1 - 6.7e-05 23.4 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK66810.1 - 0.00062 19.5 0.6 0.0015 18.2 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK66810.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK66810.1 - 0.0028 16.8 0.1 0.0059 15.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK66810.1 - 0.003 16.3 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIK66810.1 - 0.0036 16.6 0.0 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIK66810.1 - 0.0042 15.9 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 MCRA family FAD_binding_3 PF01494.19 KIK66810.1 - 0.0056 16.0 0.4 0.0086 15.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KIK66810.1 - 0.012 15.6 0.1 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Rossmann-like PF10727.9 KIK66810.1 - 0.14 12.1 0.6 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Rossmann-like domain Thi4 PF01946.17 KIK66810.1 - 0.19 11.0 0.1 0.43 9.8 0.1 1.5 2 0 0 2 2 2 0 Thi4 family HMG_box PF00505.19 KIK66811.1 - 4.8e-18 65.3 0.4 5.4e-18 65.2 0.4 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK66811.1 - 3.3e-09 37.2 0.1 3.9e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain MFS_1 PF07690.16 KIK66812.1 - 1.9e-34 119.1 31.9 1.9e-34 119.1 31.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK66813.1 - 2.8e-35 121.9 32.1 2.8e-35 121.9 32.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily YpmT PF17431.2 KIK66813.1 - 0.019 15.0 0.2 0.019 15.0 0.2 3.0 4 0 0 4 4 4 0 Uncharacterized YmpT-like AdoMet_MTase PF07757.13 KIK66814.1 - 2.4e-32 111.6 0.0 2.2e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KIK66814.1 - 0.0045 16.8 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK66814.1 - 0.0078 16.8 0.7 0.082 13.6 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK66814.1 - 0.0082 16.8 0.3 0.039 14.7 0.0 2.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK66814.1 - 0.033 14.0 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIK66814.1 - 0.074 13.8 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KIK66814.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain NACHT PF05729.12 KIK66816.1 - 5.6e-08 32.9 0.0 4e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK66816.1 - 0.0053 17.2 0.0 0.0086 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK66816.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK66816.1 - 0.2 12.1 0.0 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Pox_A14 PF05767.12 KIK66818.1 - 0.14 12.3 5.1 1 9.5 0.5 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF2975 PF11188.8 KIK66818.1 - 7.5 6.5 10.6 3.4 7.6 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) DUF4131 PF13567.6 KIK66818.1 - 8.2 6.0 8.6 7.1 6.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Retrotrans_gag PF03732.17 KIK66819.1 - 2.7e-05 24.4 0.0 0.00013 22.1 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein RtcR PF06956.11 KIK66819.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase DUF2183 PF09949.9 KIK66822.1 - 1.1e-23 83.4 0.0 3.3e-23 81.9 0.0 1.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KIK66822.1 - 0.00072 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) End_N_terminal PF12218.8 KIK66822.1 - 0.12 12.1 0.1 1.7 8.4 0.0 2.7 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase p450 PF00067.22 KIK66823.1 - 4.9e-47 160.7 0.0 6.7e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK66824.1 - 4.4e-55 187.2 0.0 5.6e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KIK66825.1 - 4.3e-13 48.9 9.4 9.8e-13 47.8 9.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK66825.1 - 5.1e-10 38.8 19.6 6.6e-10 38.4 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Atrophin-1 PF03154.15 KIK66826.1 - 0.11 10.7 0.1 0.13 10.6 0.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Plectin PF00681.20 KIK66827.1 - 0.034 14.0 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Plectin repeat KDZ PF18758.1 KIK66829.1 - 2.7e-28 99.1 0.2 3.1e-28 98.9 0.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-TAZ PF02135.16 KIK66829.1 - 0.11 13.0 2.6 0.18 12.3 2.6 1.3 1 0 0 1 1 1 0 TAZ zinc finger CxC2 PF18803.1 KIK66830.1 - 3.9e-34 117.0 1.2 5.9e-34 116.5 1.2 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK66830.1 - 1.9e-06 27.9 0.3 3e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases PGC7_Stella PF15549.6 KIK66832.1 - 0.041 13.9 3.0 5.4 7.0 0.0 2.1 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain TALPID3 PF15324.6 KIK66833.1 - 2.1 5.9 9.2 2.4 5.7 9.2 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Helicase_C PF00271.31 KIK66838.1 - 2.7e-15 56.7 0.0 4.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK66839.1 - 6.4e-10 39.1 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Plavaka PF18759.1 KIK66841.1 - 3.9e-24 85.5 0.1 4e-13 49.3 0.0 3.3 1 1 2 3 3 3 3 Plavaka transposase NLPC_P60 PF00877.19 KIK66842.1 - 0.035 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family DUF2183 PF09949.9 KIK66844.1 - 4.8e-19 68.5 0.0 7.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KIK66844.1 - 0.07 12.6 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) HMMR_N PF15905.5 KIK66846.1 - 0.0093 15.5 10.8 0.015 14.8 10.8 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KIK66846.1 - 0.0093 14.9 13.6 0.014 14.3 13.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc42p PF11544.8 KIK66846.1 - 0.014 15.4 2.8 5 7.2 0.0 3.3 2 1 0 2 2 2 0 Spindle pole body component Spc42p Csm1_N PF18504.1 KIK66846.1 - 0.026 14.9 15.5 0.055 13.8 4.2 3.4 1 1 3 4 4 4 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KIK66846.1 - 0.029 14.4 7.8 0.029 14.4 7.8 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.11 KIK66846.1 - 0.03 14.3 2.7 0.03 14.3 2.7 3.3 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 KIK66846.1 - 0.03 14.4 4.0 0.03 14.4 4.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LRS4 PF10422.9 KIK66846.1 - 0.058 13.0 10.6 0.08 12.5 10.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 YscO-like PF16789.5 KIK66846.1 - 0.073 13.1 10.4 0.11 12.5 10.4 1.2 1 0 0 1 1 1 0 YscO-like protein DUF4677 PF15726.5 KIK66846.1 - 0.074 13.2 0.6 1.6 8.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4677) MPS2 PF17060.5 KIK66846.1 - 0.098 11.9 5.1 0.16 11.2 5.1 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Fez1 PF06818.15 KIK66846.1 - 0.12 12.9 14.6 0.071 13.6 10.2 1.8 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 KIK66846.1 - 0.16 12.1 21.5 0.14 12.4 8.0 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.11 KIK66846.1 - 0.16 11.7 1.9 0.58 10.0 0.4 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) bZIP_1 PF00170.21 KIK66846.1 - 0.16 12.0 10.1 2.3 8.4 2.2 3.1 3 0 0 3 3 3 0 bZIP transcription factor BRE1 PF08647.11 KIK66846.1 - 0.17 12.0 13.1 0.53 10.4 4.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FAM76 PF16046.5 KIK66846.1 - 0.17 11.2 6.9 0.35 10.2 6.9 1.6 1 1 0 1 1 1 0 FAM76 protein GAS PF13851.6 KIK66846.1 - 0.21 10.9 16.8 0.042 13.2 4.9 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med30 PF11315.8 KIK66846.1 - 0.24 11.6 4.1 1.3 9.2 1.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 CCDC74_C PF14917.6 KIK66846.1 - 0.25 11.9 5.1 0.3 11.6 1.6 2.4 1 1 1 2 2 2 0 Coiled coil protein 74, C terminal APG6_N PF17675.1 KIK66846.1 - 0.31 11.6 24.8 0.11 13.0 15.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF812 PF05667.11 KIK66846.1 - 0.34 9.7 14.7 0.11 11.4 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) PKcGMP_CC PF16808.5 KIK66846.1 - 0.36 10.7 12.9 1.7 8.5 1.4 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Exonuc_VII_L PF02601.15 KIK66846.1 - 0.44 10.1 4.4 0.62 9.6 4.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.11 KIK66846.1 - 0.59 9.9 8.1 2.4 7.9 0.5 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 CC2-LZ PF16516.5 KIK66846.1 - 0.98 9.8 12.1 1.3 9.5 4.2 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.6 KIK66846.1 - 1 8.6 7.9 1.6 8.0 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KIK66846.1 - 1 8.3 8.9 0.94 8.5 7.5 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KIK66846.1 - 1.6 8.8 4.7 1.7 8.7 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KIK66846.1 - 3.6 7.9 12.6 29 5.0 9.6 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Dzip-like_N PF13815.6 KIK66846.1 - 4.7 7.2 13.2 3.2 7.8 1.3 2.7 2 1 1 3 3 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FtsX_ECD PF18075.1 KIK66846.1 - 4.8 7.9 6.6 5.5 7.7 2.7 2.5 1 1 1 2 2 2 0 FtsX extracellular domain Lebercilin PF15619.6 KIK66846.1 - 5.7 6.6 19.5 0.89 9.2 5.2 2.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KIK66846.1 - 8.9 5.5 17.7 3.3 6.9 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF745 PF05335.13 KIK66847.1 - 0.15 11.8 0.5 5.2 6.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 KIK66847.1 - 0.32 10.9 2.2 15 5.5 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase p450 PF00067.22 KIK66849.1 - 8.5e-52 176.4 0.0 1.1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KIK66850.1 - 1.9e-11 43.5 27.6 3.2e-10 39.5 10.8 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK66850.1 - 3.2e-10 39.5 36.6 1.1e-08 34.4 23.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1761 PF08570.10 KIK66851.1 - 0.019 15.2 3.4 0.019 15.2 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF2367 PF10164.9 KIK66852.1 - 1.3e-07 32.1 7.7 1.3e-07 32.0 7.2 1.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.9 KIK66852.1 - 0.23 11.8 6.3 0.28 11.5 6.3 1.4 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain DUF2367 PF10164.9 KIK66853.1 - 6.5e-10 39.4 2.6 6.5e-10 39.4 2.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) ATP1G1_PLM_MAT8 PF02038.16 KIK66853.1 - 0.13 11.7 4.3 0.21 11.0 4.3 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Actin PF00022.19 KIK66854.1 - 1.3e-148 495.0 0.0 7.2e-148 492.5 0.0 1.8 1 1 0 1 1 1 1 Actin GerD PF17898.1 KIK66854.1 - 0.053 13.5 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain DSPc PF00782.20 KIK66856.1 - 1.5e-23 83.0 0.0 4.9e-21 74.9 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK66856.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Zn_clus PF00172.18 KIK66858.1 - 0.0082 16.2 8.0 0.0082 16.2 8.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cut8 PF08559.10 KIK66858.1 - 0.19 11.3 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein RSN1_7TM PF02714.15 KIK66859.1 - 2.4e-69 233.7 16.6 2.4e-69 233.7 16.6 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIK66859.1 - 4.6e-43 146.7 0.7 4.6e-43 146.7 0.7 2.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIK66859.1 - 6.4e-31 107.9 0.0 1e-30 107.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KIK66859.1 - 1.1e-16 60.7 0.0 2.7e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Retrotran_gag_2 PF14223.6 KIK66860.1 - 2e-06 27.5 1.3 3.7e-06 26.6 0.4 1.8 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KIK66860.1 - 0.0027 17.7 5.4 0.0075 16.3 5.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KIK66860.1 - 0.59 9.9 3.3 0.62 9.8 0.8 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger IBR PF01485.21 KIK66860.1 - 0.59 10.4 8.7 0.25 11.6 0.6 3.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-CCHC_2 PF13696.6 KIK66860.1 - 4.8 7.1 7.7 1.8 8.5 4.0 2.2 2 0 0 2 2 2 0 Zinc knuckle MIP PF00230.20 KIK66866.1 - 3.2e-45 154.6 13.0 3.7e-45 154.4 13.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC_membrane PF00664.23 KIK66870.1 - 2.2e-39 135.8 10.0 2.7e-39 135.5 10.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIK66870.1 - 3.7e-32 111.7 0.0 6.9e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK66870.1 - 1.1e-05 25.0 0.0 0.0019 17.7 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK66870.1 - 0.00069 20.0 0.8 0.0074 16.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KIK66870.1 - 0.0017 18.2 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK66870.1 - 0.0022 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK66870.1 - 0.0054 16.7 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KIK66870.1 - 0.0056 16.4 0.0 0.02 14.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KIK66870.1 - 0.0057 17.1 0.0 0.071 13.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK66870.1 - 0.01 16.1 0.0 0.061 13.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK66870.1 - 0.035 14.6 0.1 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK66870.1 - 0.06 13.4 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIK66870.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK66870.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 KIK66870.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 KIK66872.1 - 0.0077 16.6 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 KIK66872.1 - 0.055 12.8 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 KIK66872.1 - 0.084 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 KIK66872.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain APH PF01636.23 KIK66876.1 - 2.6e-07 30.8 0.4 2.8e-05 24.2 0.3 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK66876.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KIK66876.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK66877.1 - 0.00025 21.0 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK66877.1 - 0.0063 16.1 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KIK66877.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK66878.1 - 0.00077 19.5 0.1 0.0067 16.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK66878.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-FLZ PF04570.14 KIK66880.1 - 0.013 14.9 1.7 0.013 14.9 1.7 3.6 4 0 0 4 4 4 0 zinc-finger of the FCS-type, C2-C2 zf-MYND PF01753.18 KIK66880.1 - 0.18 12.0 23.2 6.1 7.0 3.6 4.4 3 1 0 3 3 3 0 MYND finger zf-CGNR PF11706.8 KIK66880.1 - 0.23 11.3 8.4 0.36 10.7 0.1 3.6 4 0 0 4 4 4 0 CGNR zinc finger PLATZ PF04640.14 KIK66880.1 - 0.24 12.1 16.2 2.6 8.7 0.2 3.6 3 0 0 3 3 3 0 PLATZ transcription factor TFIIA PF03153.13 KIK66880.1 - 2.8 7.9 11.4 3.3 7.6 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RPAP2_Rtr1 PF04181.13 KIK66880.1 - 2.9 8.3 19.7 23 5.4 7.3 4.4 3 1 0 3 3 3 0 Rtr1/RPAP2 family Fer4_11 PF13247.6 KIK66880.1 - 5.3 7.2 13.9 2.5 8.3 0.3 3.4 3 1 0 3 3 3 0 4Fe-4S dicluster domain zf-C2H2 PF00096.26 KIK66881.1 - 0.0094 16.4 1.8 0.0094 16.4 1.8 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK66881.1 - 0.039 14.3 0.2 0.091 13.1 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK66881.1 - 0.052 14.4 4.5 0.79 10.7 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Coat_F PF07875.12 KIK66882.1 - 0.093 13.0 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Coat F domain Coq4 PF05019.13 KIK66884.1 - 2.5e-97 324.6 0.0 2.9e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF2625 PF10946.8 KIK66884.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 DUF2415 PF10313.9 KIK66885.1 - 9e-05 22.3 0.0 0.00054 19.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 KIK66885.1 - 0.041 12.8 0.1 0.96 8.3 0.1 2.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VCBS PF13517.6 KIK66885.1 - 1.4 9.5 9.9 9.8 6.9 9.9 2.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DIOX_N PF14226.6 KIK66887.1 - 4.6e-18 66.1 0.1 3.6e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK66887.1 - 1.1e-12 48.3 0.1 1.9e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5455 PF17537.2 KIK66888.1 - 0.016 15.6 2.8 0.088 13.2 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5455) Tom5 PF10642.9 KIK66888.1 - 0.22 11.6 1.2 14 5.9 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase PLDc_2 PF13091.6 KIK66890.1 - 2.9e-09 36.9 0.0 0.00081 19.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIK66890.1 - 1.6e-07 31.2 0.1 0.015 15.4 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Aldose_epim PF01263.20 KIK66891.1 - 1.4e-20 73.8 0.0 6.2e-10 38.9 0.0 3.1 2 2 0 2 2 2 2 Aldose 1-epimerase Rhabdo_ncap PF00945.18 KIK66893.1 - 0.77 8.6 3.3 0.77 8.6 3.3 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DNA_pol_phi PF04931.13 KIK66893.1 - 3.2 5.7 6.5 3.2 5.7 6.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4939 PF16297.5 KIK66897.1 - 0.034 14.0 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Phage_int_SAM_6 PF18644.1 KIK66899.1 - 8.3e-05 22.6 0.6 0.00011 22.2 0.6 1.1 1 0 0 1 1 1 1 Phage integrase SAM-like domain HIP1_clath_bdg PF16515.5 KIK66899.1 - 0.0083 16.7 3.0 0.0083 16.7 3.0 1.5 1 1 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Spc34 PF08657.10 KIK66899.1 - 0.019 14.8 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF3450 PF11932.8 KIK66899.1 - 0.022 14.1 3.1 0.029 13.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF745 PF05335.13 KIK66899.1 - 0.23 11.2 5.2 0.29 10.9 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DASH_Duo1 PF08651.10 KIK66899.1 - 0.26 11.1 6.7 2.6 7.9 0.8 2.3 1 1 1 2 2 2 0 DASH complex subunit Duo1 MFS_1 PF07690.16 KIK66902.1 - 5.1e-07 28.9 13.1 6.3e-07 28.6 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK66903.1 - 6.2e-06 25.4 6.9 6.2e-06 25.4 6.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1361 PF07099.11 KIK66904.1 - 0.0041 17.1 0.5 0.0047 16.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) AA_permease PF00324.21 KIK66906.1 - 7.4e-127 423.8 31.8 9.3e-127 423.5 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK66906.1 - 4e-33 114.9 36.4 5e-33 114.6 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease ApbA_C PF08546.11 KIK66907.1 - 1.9e-16 60.4 0.0 1.1e-14 54.7 0.0 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIK66907.1 - 7.2e-15 54.9 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF4286 PF14114.6 KIK66909.1 - 1.8e-05 25.1 0.4 0.0019 18.6 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4286) EthD PF07110.11 KIK66909.1 - 0.035 15.2 0.1 0.13 13.4 0.1 2.1 2 1 0 2 2 2 0 EthD domain Aminotran_4 PF01063.19 KIK66910.1 - 0.0039 17.1 0.0 0.13 12.1 0.0 2.2 1 1 1 2 2 2 2 Amino-transferase class IV Sporozoite_P67 PF05642.11 KIK66911.1 - 0.036 12.2 0.1 0.038 12.1 0.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DARPP-32 PF05395.12 KIK66911.1 - 0.037 14.3 1.2 0.054 13.7 1.2 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 MerC PF03203.14 KIK66914.1 - 0.079 13.4 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein WD40 PF00400.32 KIK66916.1 - 7.7e-61 200.6 44.5 4.4e-09 36.8 0.1 9.9 7 2 2 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66916.1 - 5.9e-23 81.0 1.2 0.015 15.6 0.0 7.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66916.1 - 9.2e-18 63.7 0.7 1.8 8.6 0.0 8.5 8 0 0 8 8 8 6 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK66916.1 - 2.1e-07 29.6 0.0 1.3 7.2 0.0 5.1 4 2 0 5 5 5 3 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK66916.1 - 2.9e-05 23.2 1.7 13 4.7 0.0 6.2 4 3 2 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK66916.1 - 6.7e-05 22.9 0.0 1.3 8.8 0.0 3.7 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 KIK66916.1 - 0.00061 20.2 0.0 0.0071 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Gmad1 PF10647.9 KIK66916.1 - 0.001 18.9 8.4 0.11 12.2 1.7 4.8 1 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain NACHT PF05729.12 KIK66916.1 - 0.0013 18.7 0.1 0.011 15.6 0.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK66916.1 - 0.0052 17.2 0.0 0.024 15.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK66916.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KIK66916.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Cuticle_4 PF15955.5 KIK66916.1 - 0.022 15.5 5.3 68 4.3 0.0 6.2 6 1 1 7 7 7 0 Cuticle protein AAA_7 PF12775.7 KIK66916.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4596 PF15363.6 KIK66916.1 - 0.1 12.9 1.3 42 4.5 0.1 4.1 5 0 0 5 5 4 0 Domain of unknown function (DUF4596) PQQ_3 PF13570.6 KIK66916.1 - 0.11 13.0 1.3 36 5.0 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain AAA_22 PF13401.6 KIK66916.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK66916.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF3025 PF11227.8 KIK66917.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) zf_C2H2_ZHX PF18387.1 KIK66918.1 - 0.045 13.4 0.3 0.09 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_ZIC PF18366.1 KIK66918.1 - 0.091 12.9 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Zic proteins zinc finger domain Ifi-6-16 PF06140.13 KIK66922.1 - 2.5e-05 24.1 22.2 4.1e-05 23.4 22.2 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF5601 PF18151.1 KIK66922.1 - 0.011 16.0 0.3 5.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) PatG_C PF18065.1 KIK66922.1 - 0.019 14.9 0.4 0.74 9.8 0.0 2.6 1 1 2 3 3 3 0 PatG C-terminal Fungal_trans PF04082.18 KIK66923.1 - 1.6e-27 96.2 0.0 5.7e-26 91.1 0.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK66923.1 - 8.2e-11 41.8 7.3 1.4e-10 41.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIK66923.1 - 0.00011 22.3 0.7 0.00025 21.1 0.7 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain DUF1752 PF08550.10 KIK66924.1 - 1.2e-10 41.0 0.6 2e-10 40.3 0.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ifi-6-16 PF06140.13 KIK66925.1 - 2.4e-05 24.1 16.2 4.1e-05 23.4 16.2 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 KIK66926.1 - 3.4e-05 23.7 16.1 5.5e-05 23.0 16.1 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family RD3 PF14473.6 KIK66926.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.5 1 1 0 1 1 1 0 RD3 protein DUF3237 PF11578.8 KIK66928.1 - 0.00073 19.4 0.0 0.00095 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) RicinB_lectin_2 PF14200.6 KIK66929.1 - 1.4e-12 48.1 6.4 0.00026 21.7 0.1 5.1 5 2 3 8 8 8 3 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 KIK66929.1 - 0.0056 16.5 0.6 2.4 8.0 0.0 4.3 3 1 1 4 4 4 1 Peptidase inhibitor I66 zf-MYND PF01753.18 KIK66930.1 - 2.9e-10 40.1 10.9 2.9e-10 40.1 10.9 2.0 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIK66930.1 - 0.94 9.8 10.2 0.81 10.0 8.4 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 KIK66930.1 - 3.2 5.5 4.8 4 5.2 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 WD40 PF00400.32 KIK66931.1 - 3.2e-112 363.2 32.7 1.2e-09 38.6 0.0 11.7 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66931.1 - 7.3e-47 157.6 5.0 0.0022 18.2 0.0 11.0 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66931.1 - 2.3e-22 78.4 15.6 0.91 9.5 0.0 11.4 11 0 0 11 11 11 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66931.1 - 1.1e-14 54.2 3.2 2.7 6.9 0.0 10.2 4 3 6 11 11 11 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK66931.1 - 4.4e-10 39.4 0.0 2.1 7.6 0.0 7.1 4 3 3 8 8 8 3 WD40-like domain Nup160 PF11715.8 KIK66931.1 - 1.7e-07 30.3 8.7 12 4.4 0.1 9.2 5 3 3 10 10 10 0 Nucleoporin Nup120/160 PQQ PF01011.21 KIK66931.1 - 7.8e-07 28.7 0.0 50 4.1 0.0 8.2 9 0 0 9 9 9 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK66931.1 - 6.4e-06 26.5 2.5 11 6.6 0.0 7.0 3 2 7 10 10 10 0 PQQ-like domain Cuticle_4 PF15955.5 KIK66931.1 - 1.5e-05 25.6 14.3 10 6.9 0.0 8.9 11 0 0 11 11 10 0 Cuticle protein Peptidase_S9_N PF02897.15 KIK66931.1 - 4.1e-05 22.6 0.2 2.9 6.6 0.0 5.8 3 3 3 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 KIK66931.1 - 6.4e-05 22.5 11.4 64 3.4 0.0 8.9 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature DUF4784 PF16023.5 KIK66931.1 - 0.00017 20.7 0.0 5.6 5.8 0.0 5.8 2 2 3 7 7 7 1 Domain of unknown function (DUF4784) HARP PF07443.13 KIK66931.1 - 0.00018 21.0 0.5 19 5.0 0.0 6.3 8 0 0 8 8 8 0 HepA-related protein (HARP) Frtz PF11768.8 KIK66931.1 - 0.00095 17.6 0.0 42 2.3 0.0 6.4 2 2 4 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz VMR2 PF17055.5 KIK66931.1 - 0.0052 16.6 0.0 3.3 7.4 0.0 4.1 3 1 1 6 6 5 1 Viral matrix protein M2 YmaF PF12788.7 KIK66931.1 - 0.031 14.8 4.0 15 6.2 0.1 5.0 4 1 2 6 6 5 0 YmaF family COPI_C PF06957.11 KIK66931.1 - 0.11 11.2 0.0 34 3.0 0.0 3.3 1 1 2 3 3 3 0 Coatomer (COPI) alpha subunit C-terminus nos_propeller PF18764.1 KIK66931.1 - 3.5 7.6 8.7 71 3.4 0.0 6.4 9 0 0 9 9 9 0 Nitrous oxide reductase propeller repeat WD40 PF00400.32 KIK66938.1 - 7.6e-101 327.2 53.2 1e-09 38.8 0.4 12.5 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66938.1 - 7.9e-38 128.6 4.9 0.013 15.8 0.0 11.3 1 1 10 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66938.1 - 3.5e-18 65.1 5.7 1.4 9.0 0.0 10.8 11 0 0 11 11 11 5 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK66938.1 - 9.5e-09 35.0 0.0 1.8 7.8 0.0 8.7 6 3 5 11 11 11 1 WD40-like domain Nup160 PF11715.8 KIK66938.1 - 7.2e-08 31.5 0.0 14 4.2 0.0 8.7 10 0 0 10 10 10 0 Nucleoporin Nup120/160 NACHT PF05729.12 KIK66938.1 - 3.2e-06 27.2 0.0 6.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66938.1 - 5e-05 23.7 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK66938.1 - 0.0021 18.0 0.0 0.0057 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK66938.1 - 0.0073 16.7 0.1 0.085 13.2 0.0 2.7 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 KIK66938.1 - 0.0086 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF4873 PF16170.5 KIK66938.1 - 0.011 15.9 13.8 6.9 7.0 0.1 6.3 2 2 5 7 7 7 0 Domain of unknown function (DUF4873) NB-ARC PF00931.22 KIK66938.1 - 0.016 14.4 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KIK66938.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK66938.1 - 0.047 14.2 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 KIK66938.1 - 0.067 13.5 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK66938.1 - 0.091 13.3 2.0 0.18 12.3 0.1 2.6 3 1 0 3 3 2 0 AAA domain PsaL PF02605.15 KIK66938.1 - 0.13 11.9 0.1 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Proteasome_A_N PF10584.9 KIK66938.1 - 5.7 6.7 16.2 54 3.6 0.1 6.5 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature CxC6 PF18721.1 KIK66940.1 - 9.4e-20 70.7 6.9 1.1e-19 70.4 6.9 1.1 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases zf-RAG1 PF10426.9 KIK66940.1 - 0.017 15.2 0.4 0.19 11.9 0.1 2.3 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain WD40 PF00400.32 KIK66944.1 - 2.1e-75 246.7 12.3 2.8e-11 43.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66944.1 - 4.8e-23 81.3 0.2 0.0021 18.3 0.0 6.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK66944.1 - 3.8e-17 62.8 0.0 5.2e-05 23.2 0.0 3.7 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK66944.1 - 1.7e-12 47.3 0.1 0.78 9.0 0.0 6.0 4 2 1 6 6 6 4 WD40-like domain Nup160 PF11715.8 KIK66944.1 - 1.2e-09 37.4 2.0 0.069 11.8 0.0 5.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK66944.1 - 3e-07 29.7 0.1 0.83 8.5 0.0 4.6 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NHL PF01436.21 KIK66944.1 - 6.9e-07 29.0 0.9 2.8 8.1 0.0 5.8 7 0 0 7 7 7 1 NHL repeat Cytochrom_D1 PF02239.16 KIK66944.1 - 1.2e-05 24.0 0.3 0.24 9.9 0.0 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.12 KIK66944.1 - 5.2e-05 23.1 0.0 14 5.7 0.0 5.3 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 KIK66944.1 - 0.00038 20.3 6.7 18 5.3 0.0 5.6 6 0 0 6 6 6 0 Nitrous oxide reductase propeller repeat Proteasome_A_N PF10584.9 KIK66944.1 - 0.0033 17.1 0.5 35 4.2 0.0 5.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PQQ_3 PF13570.6 KIK66944.1 - 0.0049 17.3 17.5 2.8 8.6 1.8 6.4 4 2 3 7 7 6 2 PQQ-like domain DUF5570 PF17731.1 KIK66944.1 - 0.01 15.9 3.3 3.9 7.6 0.2 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5570) Peptidase_S9_N PF02897.15 KIK66944.1 - 0.031 13.1 0.0 18 4.0 0.0 3.3 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DsbC_N PF10411.9 KIK66944.1 - 0.036 13.5 2.5 93 2.6 0.0 5.2 6 0 0 6 6 6 0 Disulfide bond isomerase protein N-terminus DPPIV_N PF00930.21 KIK66944.1 - 0.064 12.0 0.4 2.2 6.9 0.0 3.5 2 2 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region FlgT_M PF16539.5 KIK66944.1 - 0.16 12.1 0.4 45 4.1 0.0 3.2 3 1 1 4 4 4 0 Flagellar assembly protein T, middle domain PA-IIL PF07472.11 KIK66948.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) KDZ PF18758.1 KIK66950.1 - 4e-14 52.8 1.5 4.7e-14 52.5 1.5 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK66952.1 - 2.4e-48 164.7 0.1 2.8e-48 164.5 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK66953.1 - 1.2e-30 105.8 2.0 1.2e-30 105.8 2.0 1.5 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK66953.1 - 0.00043 20.4 0.6 0.00071 19.7 0.6 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK66953.1 - 0.0081 16.0 1.0 0.014 15.2 0.8 1.6 1 1 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CENP-B_dimeris PF09026.10 KIK66959.1 - 3.1 8.3 8.4 3.9 7.9 8.4 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NACHT PF05729.12 KIK66961.1 - 2e-06 27.8 0.0 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66961.1 - 2.2e-06 28.2 0.0 2.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIK66961.1 - 6.1e-05 22.8 0.0 6.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK66961.1 - 0.00039 20.4 0.0 0.00057 19.9 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KIK66961.1 - 0.00062 19.7 0.1 0.29 11.0 0.1 2.1 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_22 PF13401.6 KIK66961.1 - 0.0008 19.7 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK66961.1 - 0.0018 17.5 0.1 0.0022 17.3 0.1 1.3 1 1 0 1 1 1 1 NB-ARC domain Cytidylate_kin PF02224.18 KIK66961.1 - 0.003 17.3 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_19 PF13245.6 KIK66961.1 - 0.0032 17.8 0.1 0.004 17.5 0.1 1.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK66961.1 - 0.0054 17.1 0.1 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KIK66961.1 - 0.007 16.9 0.1 0.011 16.2 0.1 1.5 1 1 0 1 1 1 1 ABC transporter NTPase_1 PF03266.15 KIK66961.1 - 0.0073 16.2 0.1 0.0082 16.1 0.1 1.4 1 1 0 1 1 1 1 NTPase AAA_7 PF12775.7 KIK66961.1 - 0.0092 15.5 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PIF1 PF05970.14 KIK66961.1 - 0.011 14.9 0.1 0.021 14.0 0.1 1.4 1 1 0 1 1 1 0 PIF1-like helicase AAA PF00004.29 KIK66961.1 - 0.015 15.7 0.4 0.038 14.4 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIK66961.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KIK66961.1 - 0.032 14.8 0.6 0.052 14.1 0.6 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK66961.1 - 0.035 14.0 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 KIK66961.1 - 0.042 12.8 0.1 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KIK66961.1 - 0.043 13.7 0.0 0.067 13.1 0.0 1.5 1 1 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KIK66961.1 - 0.057 13.6 0.2 0.094 12.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIK66961.1 - 0.07 12.9 0.2 0.099 12.4 0.2 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 KIK66961.1 - 0.079 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Herpes_Helicase PF02689.14 KIK66961.1 - 0.084 10.8 0.0 0.084 10.8 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_23 PF13476.6 KIK66961.1 - 0.1 13.1 0.3 0.61 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KIK66961.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein DUF87 PF01935.17 KIK66961.1 - 0.2 11.7 0.5 0.51 10.4 0.2 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain WD40 PF00400.32 KIK66962.1 - 8.5e-108 349.2 40.8 1.2e-09 38.6 0.3 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66962.1 - 6.3e-43 145.0 3.8 0.0023 18.2 0.0 11.0 1 1 9 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66962.1 - 8.6e-27 92.5 11.3 0.57 10.2 0.0 11.3 11 0 0 11 11 11 9 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66962.1 - 4.4e-14 52.2 0.1 1.5 7.7 0.0 10.1 6 3 3 11 11 11 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK66962.1 - 1.9e-10 41.0 0.0 0.011 15.6 0.0 4.2 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK66962.1 - 4.8e-09 36.0 0.0 2.1 7.6 0.0 8.2 8 2 1 9 9 9 1 WD40-like domain Nup160 PF11715.8 KIK66962.1 - 4.9e-08 32.1 0.2 14 4.2 0.0 8.5 10 0 0 10 10 10 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KIK66962.1 - 1.2e-06 28.1 12.3 63 3.4 0.0 9.6 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature 5-FTHF_cyc-lig PF01812.20 KIK66962.1 - 4.2e-05 23.5 0.6 54 3.6 0.0 7.0 7 2 1 9 9 9 0 5-formyltetrahydrofolate cyclo-ligase family Peptidase_S9_N PF02897.15 KIK66962.1 - 0.0007 18.5 0.1 25 3.5 0.0 5.5 2 1 4 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4873 PF16170.5 KIK66962.1 - 0.0009 19.4 11.1 1.7 8.9 0.1 6.1 2 2 5 7 7 7 2 Domain of unknown function (DUF4873) Frtz PF11768.8 KIK66962.1 - 0.002 16.5 0.0 49 2.0 0.0 6.3 4 3 4 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz Imm17 PF15562.6 KIK66962.1 - 0.059 13.2 0.3 2.6e+02 1.5 0.0 5.7 7 0 0 7 7 7 0 Immunity protein 17 Cuticle_4 PF15955.5 KIK66962.1 - 2.2 9.0 7.4 6.9e+02 1.0 0.1 6.9 10 0 0 10 10 10 0 Cuticle protein CxC2 PF18803.1 KIK66964.1 - 1.9e-29 102.0 2.1 2.9e-29 101.4 2.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK66964.1 - 0.00051 20.2 1.1 0.00075 19.6 1.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK66964.1 - 0.006 16.4 0.9 0.01 15.7 0.7 1.5 1 1 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases DUF5407 PF17401.2 KIK66971.1 - 0.044 14.1 0.6 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5407) DUF1664 PF07889.12 KIK66971.1 - 0.06 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IDEAL PF08858.10 KIK66971.1 - 0.098 12.4 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 IDEAL domain CAP_N PF01213.19 KIK66971.1 - 0.14 11.6 2.8 0.2 11.1 2.8 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NACHT PF05729.12 KIK66972.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK66972.1 - 1.5e-05 25.4 0.0 1.9e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIK66972.1 - 0.0016 18.2 0.0 0.0018 18.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK66972.1 - 0.0019 18.5 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK66972.1 - 0.0024 17.1 0.0 0.0026 17.0 0.0 1.2 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK66972.1 - 0.0026 18.3 0.0 0.0044 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK66972.1 - 0.0027 17.7 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK66972.1 - 0.0047 17.3 0.0 0.024 15.0 0.0 1.9 2 0 0 2 2 2 1 RNA helicase APS_kinase PF01583.20 KIK66972.1 - 0.0057 16.6 0.4 0.091 12.6 0.4 2.0 1 1 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.27 KIK66972.1 - 0.018 15.6 0.0 0.023 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter ATPase PF06745.13 KIK66972.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA PF00004.29 KIK66972.1 - 0.053 14.0 0.3 0.15 12.5 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK66972.1 - 0.06 12.9 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KIK66972.1 - 0.1 13.0 0.1 0.17 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK66972.1 - 0.16 12.1 0.4 0.25 11.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK66973.1 - 4e-109 353.4 45.6 1.3e-09 38.5 0.3 13.5 14 0 0 14 14 14 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66973.1 - 5.1e-50 167.7 6.9 0.00087 19.5 0.0 12.0 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK66973.1 - 2.9e-21 74.8 11.3 0.65 10.0 0.0 12.0 12 0 0 12 12 12 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK66973.1 - 2.6e-13 49.7 1.6 4.6 6.1 0.0 10.7 8 3 3 12 12 12 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK66973.1 - 1.2e-12 47.8 0.0 0.47 9.7 0.0 9.0 5 4 2 8 8 8 2 WD40-like domain Gmad1 PF10647.9 KIK66973.1 - 1.3e-11 44.7 17.1 0.029 14.1 0.4 8.4 1 1 7 9 9 9 5 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.6 KIK66973.1 - 1.1e-10 41.6 0.3 1.4 9.5 0.0 8.4 2 2 9 11 11 11 1 PQQ-like domain Nup160 PF11715.8 KIK66973.1 - 1.2e-09 37.5 3.2 5.3 5.6 0.0 9.6 7 3 4 11 11 11 1 Nucleoporin Nup120/160 PQQ PF01011.21 KIK66973.1 - 1.3e-06 28.0 0.0 12 6.0 0.0 8.8 11 0 0 11 11 11 0 PQQ enzyme repeat Ret2_MD PF18528.1 KIK66973.1 - 4.7e-06 26.9 0.0 43 4.6 0.0 6.3 4 1 3 7 7 7 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KIK66973.1 - 5.2e-05 21.8 0.0 13 4.0 0.0 7.0 6 2 2 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5018 PF16410.5 KIK66973.1 - 0.00094 18.0 0.1 4.2 6.0 0.0 4.4 3 1 2 5 5 5 1 Domain of unknown function (DUF5018) SoxZ PF08770.11 KIK66973.1 - 0.016 15.0 0.0 15 5.4 0.0 4.6 6 0 0 6 6 6 0 Sulphur oxidation protein SoxZ nos_propeller PF18764.1 KIK66973.1 - 0.017 15.0 2.5 87 3.1 0.0 5.9 6 0 0 6 6 6 0 Nitrous oxide reductase propeller repeat Plk4_PB1 PF18190.1 KIK66973.1 - 0.018 15.2 0.8 13 6.0 0.0 5.4 4 2 3 7 7 7 0 Polo-like Kinase 4 Polo Box 1 5-FTHF_cyc-lig PF01812.20 KIK66973.1 - 0.024 14.5 0.0 56 3.5 0.0 5.3 8 0 0 8 8 8 0 5-formyltetrahydrofolate cyclo-ligase family DUF4402 PF14352.6 KIK66973.1 - 0.1 13.3 18.7 1.5 9.5 0.1 5.3 2 2 2 5 5 5 0 Domain of unknown function (DUF4402) Cuticle_4 PF15955.5 KIK66973.1 - 0.38 11.5 13.6 33 5.3 0.1 7.0 9 0 0 9 9 8 0 Cuticle protein Proteasome_A_N PF10584.9 KIK66973.1 - 0.61 9.8 13.9 81 3.0 0.0 8.0 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature DUF4265 PF14085.6 KIK66973.1 - 0.89 9.5 4.9 32 4.5 0.0 5.4 8 1 1 9 9 7 0 Domain of unknown function (DUF4265) WD40 PF00400.32 KIK66981.1 - 5.3e-35 118.8 9.4 2.3e-09 37.7 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK66981.1 - 1.8e-14 53.8 0.1 0.0066 16.7 0.0 4.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK66981.1 - 6.2e-10 39.2 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK66981.1 - 7.5e-06 25.7 1.4 2.1 8.4 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KIK66981.1 - 1.2e-05 25.8 0.0 2.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Gmad1 PF10647.9 KIK66981.1 - 0.00012 21.9 0.4 8.4 6.1 0.0 3.8 1 1 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain AAA_22 PF13401.6 KIK66981.1 - 0.0027 18.0 0.0 0.0065 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK66981.1 - 0.0035 16.6 0.1 0.019 14.2 0.0 2.2 2 1 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KIK66981.1 - 0.017 15.6 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK66981.1 - 0.024 15.0 0.0 0.096 13.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase PsaL PF02605.15 KIK66981.1 - 0.059 13.0 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI ABC_tran PF00005.27 KIK66981.1 - 0.059 13.9 0.1 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 KIK66981.1 - 0.091 13.2 1.1 0.41 11.1 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIK66981.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.9 KIK66981.1 - 0.24 11.1 0.6 1.2e+02 2.5 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Homez PF11569.8 KIK66983.1 - 0.049 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Spexin PF15171.6 KIK66987.1 - 0.048 13.9 0.4 0.15 12.3 0.4 1.9 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin SR-25 PF10500.9 KIK66987.1 - 3.9 7.0 11.8 0.47 10.0 6.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KIK66987.1 - 8.2 7.2 12.0 5.8 7.7 8.7 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Vps36_ESCRT-II PF11605.8 KIK66988.1 - 0.12 12.6 0.1 0.73 10.1 0.0 2.3 2 1 1 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 SPX PF03105.19 KIK66988.1 - 0.29 11.0 7.3 0.36 10.7 7.3 1.1 1 0 0 1 1 1 0 SPX domain PWI PF01480.17 KIK66989.1 - 0.092 13.1 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 PWI domain KDZ PF18758.1 KIK66993.1 - 4.4e-60 203.1 0.6 5.5e-60 202.8 0.6 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK66993.1 - 0.036 14.2 0.1 0.093 12.9 0.1 1.7 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases IQCJ-SCHIP1 PF15157.6 KIK66996.1 - 0.078 12.8 0.7 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Zn_clus PF00172.18 KIK66997.1 - 0.0011 19.0 7.6 0.26 11.4 1.0 3.1 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SKA2 PF16740.5 KIK66997.1 - 0.014 15.1 4.1 0.014 15.1 4.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Dfp1_Him1_M PF08630.10 KIK66998.1 - 0.05 13.8 0.0 0.05 13.8 0.0 1.0 1 0 0 1 1 1 0 Dfp1/Him1, central region DDE_3 PF13358.6 KIK66998.1 - 0.061 13.1 0.0 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3684 PF12449.8 KIK67000.1 - 0 1151.9 0.0 0 1151.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Nuc_sug_transp PF04142.15 KIK67001.1 - 1.6e-93 313.3 15.3 1.9e-92 309.8 15.3 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KIK67001.1 - 0.0028 17.0 0.6 0.0028 17.0 0.6 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 KIK67001.1 - 0.013 15.6 6.9 0.013 15.6 6.9 2.7 2 1 0 2 2 2 0 EamA-like transporter family UAA PF08449.11 KIK67001.1 - 0.11 11.7 13.1 0.23 10.6 13.1 1.5 1 1 0 1 1 1 0 UAA transporter family Chitin_synth_2 PF03142.15 KIK67002.1 - 2.1e-243 808.7 0.0 2.8e-243 808.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KIK67002.1 - 1.3e-16 61.3 0.1 5.6e-15 55.9 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIK67002.1 - 3.1e-13 50.1 10.4 1.2e-12 48.2 7.0 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KIK67002.1 - 0.0025 17.3 0.1 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KIK67002.1 - 0.02 14.7 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.20 KIK67004.1 - 0.00014 21.6 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KIK67004.1 - 0.001 18.7 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KIK67004.1 - 0.046 13.3 0.6 0.11 12.1 0.7 1.6 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KIK67004.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_14 PF13428.6 KIK67005.1 - 1.1e-28 97.4 33.1 0.0002 21.9 1.0 16.9 12 4 6 18 18 17 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK67005.1 - 8.9e-27 91.8 26.2 0.0013 18.5 0.0 12.8 14 0 0 14 14 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67005.1 - 2.1e-26 89.9 43.8 0.0013 18.6 0.1 16.9 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_8 PF13181.6 KIK67005.1 - 9e-26 87.9 23.0 0.0038 17.3 0.0 14.4 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_16 PF13432.6 KIK67005.1 - 6.9e-25 87.4 39.4 3e-05 24.6 2.8 12.7 9 3 4 13 13 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 KIK67005.1 - 2.4e-23 81.5 15.3 0.0032 17.1 0.2 10.1 9 1 1 10 10 9 5 TPR repeat TPR_19 PF14559.6 KIK67005.1 - 9.7e-21 74.1 33.5 5.5e-06 26.8 0.4 11.7 8 5 2 12 12 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK67005.1 - 2.2e-19 69.5 39.1 1.4e-05 25.3 0.1 11.6 9 3 6 15 15 14 7 Tetratricopeptide repeat TPR_17 PF13431.6 KIK67005.1 - 7.6e-17 60.4 23.5 0.023 15.1 0.4 12.9 13 1 1 14 14 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK67005.1 - 1.3e-11 44.5 12.2 0.012 15.8 0.1 9.7 7 4 2 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIK67005.1 - 2e-11 43.9 32.4 0.11 12.7 1.6 12.7 12 3 3 15 15 15 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK67005.1 - 6.5e-10 39.0 12.0 9.8 7.1 0.0 11.4 10 1 0 10 10 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK67005.1 - 1.5e-09 37.2 21.0 0.17 12.0 0.0 9.8 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 KIK67005.1 - 3.3e-05 23.2 11.4 0.12 11.6 0.2 6.7 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 KIK67005.1 - 0.00016 21.9 5.1 0.019 15.3 0.1 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK67005.1 - 0.00048 20.1 8.4 31 4.7 0.0 7.2 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KIK67005.1 - 0.0033 16.5 0.9 4.6 6.1 0.0 4.1 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KIK67005.1 - 0.0062 16.4 10.3 2 8.4 0.1 7.2 6 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KIK67005.1 - 0.0078 16.3 1.8 0.57 10.3 0.0 4.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 Coatomer_WDAD PF04053.14 KIK67005.1 - 0.0096 15.0 0.2 0.58 9.1 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region NARP1 PF12569.8 KIK67005.1 - 0.016 14.2 3.2 3.8 6.3 0.0 3.5 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 KIK67005.1 - 0.11 12.2 0.2 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) FAT PF02259.23 KIK67005.1 - 0.13 11.4 6.7 6 6.0 0.1 4.6 4 1 0 4 4 4 0 FAT domain BTAD PF03704.17 KIK67005.1 - 9.6 6.6 16.6 3.9 7.9 0.3 5.6 6 1 0 6 6 6 0 Bacterial transcriptional activator domain LETM1 PF07766.13 KIK67006.1 - 4.7e-23 81.9 1.2 3.2e-11 43.1 0.0 2.6 3 0 0 3 3 3 2 LETM1-like protein APS_kinase PF01583.20 KIK67007.1 - 7.5e-72 240.4 0.0 9e-72 240.1 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KIK67007.1 - 0.00021 21.5 0.0 0.00079 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK67007.1 - 0.00054 20.5 0.0 0.00072 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK67007.1 - 0.0092 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 KIK67007.1 - 0.013 14.9 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 G-alpha PF00503.20 KIK67007.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit CPT PF07931.12 KIK67007.1 - 0.16 11.8 0.1 0.36 10.6 0.1 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein eIF-3c_N PF05470.12 KIK67008.1 - 6.7e-177 589.4 23.3 2.4e-145 485.2 6.6 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KIK67008.1 - 3.7e-14 53.1 0.7 4.8e-13 49.5 0.0 2.8 3 0 0 3 3 3 1 PCI domain LepB_GAP_N PF18172.1 KIK67008.1 - 0.016 15.1 1.7 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain FliJ PF02050.16 KIK67008.1 - 0.11 12.7 13.8 0.26 11.5 1.0 4.1 3 0 0 3 3 3 0 Flagellar FliJ protein SYF2 PF08231.12 KIK67008.1 - 0.31 11.4 9.0 0.05 14.0 1.3 2.9 3 0 0 3 3 3 0 SYF2 splicing factor CDC45 PF02724.14 KIK67008.1 - 5.2 5.2 12.5 13 4.0 12.5 1.6 1 0 0 1 1 1 0 CDC45-like protein Rpp20 PF12328.8 KIK67008.1 - 5.8 6.9 7.7 1.8 8.6 0.0 3.3 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P Romo1 PF10247.9 KIK67009.1 - 0.25 11.8 2.6 11 6.4 0.2 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Peptidase_C15 PF01470.17 KIK67010.1 - 9.9e-08 32.4 0.0 0.017 15.3 0.0 2.6 2 1 0 2 2 2 2 Pyroglutamyl peptidase GNAT_C PF18164.1 KIK67010.1 - 0.06 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 GNAT-like C-terminal domain MgsA_C PF12002.8 KIK67011.1 - 1.4e-57 194.3 0.7 2.4e-57 193.5 0.7 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.29 KIK67011.1 - 2.4e-18 66.8 0.0 6.9e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 KIK67011.1 - 6.1e-16 58.5 1.8 8.4e-16 58.1 0.7 1.8 2 0 0 2 2 1 1 AAA C-terminal domain RuvB_N PF05496.12 KIK67011.1 - 1.1e-11 44.8 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK67011.1 - 7.2e-08 33.0 0.5 0.0023 18.4 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KIK67011.1 - 5.3e-07 29.7 0.1 4.6e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIK67011.1 - 2.1e-06 27.5 0.0 0.00015 21.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIK67011.1 - 2.7e-06 26.9 0.1 0.054 12.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIK67011.1 - 1.2e-05 25.6 0.6 0.0039 17.5 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KIK67011.1 - 0.00016 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK67011.1 - 0.0004 20.9 0.0 0.00083 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIK67011.1 - 0.00058 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KIK67011.1 - 0.00063 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 KIK67011.1 - 0.00073 19.7 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 KIK67011.1 - 0.0051 16.6 0.0 0.12 12.2 0.0 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit NB-ARC PF00931.22 KIK67011.1 - 0.0064 15.7 0.1 0.041 13.1 0.0 2.0 1 1 1 2 2 2 1 NB-ARC domain AAA_28 PF13521.6 KIK67011.1 - 0.0083 16.4 0.0 0.022 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK67011.1 - 0.0088 16.4 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KIK67011.1 - 0.014 15.9 0.0 0.035 14.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KIK67011.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Resolvase PF00239.21 KIK67011.1 - 0.022 14.8 0.2 0.046 13.8 0.2 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain ATPase_2 PF01637.18 KIK67011.1 - 0.025 14.5 0.1 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIK67011.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_3 PF07726.11 KIK67011.1 - 0.04 13.8 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Minor_capsid_2 PF11114.8 KIK67011.1 - 0.04 13.9 0.3 0.074 13.1 0.3 1.4 1 0 0 1 1 1 0 Minor capsid protein ResIII PF04851.15 KIK67011.1 - 0.044 13.8 0.1 4.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 KIK67011.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_17 PF13207.6 KIK67011.1 - 0.094 13.1 0.1 0.29 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KIK67011.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 KIK67011.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KIK67011.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein adh_short_C2 PF13561.6 KIK67012.1 - 1.1e-46 159.3 0.3 1.3e-46 159.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK67012.1 - 8.5e-35 120.0 0.7 1.1e-34 119.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK67012.1 - 4e-10 39.9 0.1 5.5e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 KIK67012.1 - 0.0028 17.1 0.1 0.0035 16.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KIK67012.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Polysacc_synt_2 PF02719.15 KIK67012.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 KIK67013.1 - 7.1e-58 196.5 0.0 1.3e-57 195.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIK67014.1 - 2.9e-60 204.2 0.0 3.8e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK67014.1 - 7.6e-37 127.0 0.0 1.3e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK67014.1 - 1.1e-06 28.0 0.4 1.7e-05 24.1 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK67014.1 - 1.3e-05 25.0 0.3 5.5e-05 22.9 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK67014.1 - 0.00017 20.9 0.0 0.00044 19.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK67014.1 - 0.00031 20.1 0.3 0.48 9.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK67014.1 - 0.00089 18.4 0.1 0.0021 17.2 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK67014.1 - 0.0038 17.4 1.0 0.012 15.8 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK67014.1 - 0.011 15.0 0.3 0.13 11.5 0.1 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KIK67014.1 - 0.038 12.7 0.3 0.055 12.2 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KIK67014.1 - 0.076 12.3 1.1 0.15 11.4 1.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK67014.1 - 0.083 11.7 0.3 0.13 11.0 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KIK67014.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KIK67015.1 - 3e-56 191.0 0.0 4e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK67015.1 - 7.2e-38 130.3 0.1 1.2e-37 129.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KIK67015.1 - 3.2e-05 23.3 0.1 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK67015.1 - 0.0003 20.5 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK67015.1 - 0.00048 19.3 0.0 0.00068 18.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK67015.1 - 0.0024 17.1 0.0 0.024 13.8 0.0 2.0 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK67015.1 - 0.0042 16.4 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK67015.1 - 0.0045 16.3 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK67015.1 - 0.011 15.9 0.0 0.044 14.0 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK67015.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Epimerase PF01370.21 KIK67016.1 - 7.3e-19 68.2 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK67016.1 - 9.2e-16 57.7 0.0 1.7e-15 56.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK67016.1 - 4.2e-10 39.8 0.5 6.2e-10 39.3 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIK67016.1 - 2.2e-09 37.2 0.5 5.2e-09 35.9 0.0 1.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK67016.1 - 5.8e-09 35.5 0.1 1.1e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIK67016.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KIK67016.1 - 0.0021 18.0 0.8 0.0048 16.8 0.3 1.9 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 KIK67016.1 - 0.0075 15.7 0.2 0.034 13.6 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK67016.1 - 0.015 15.6 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Perilipin PF03036.16 KIK67016.1 - 0.032 13.3 0.2 0.047 12.7 0.2 1.2 1 0 0 1 1 1 0 Perilipin family Peptidase_M50 PF02163.22 KIK67016.1 - 0.05 12.9 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M50 LisH PF08513.11 KIK67016.1 - 0.17 11.9 0.9 0.31 11.1 0.2 1.8 2 0 0 2 2 2 0 LisH Epimerase PF01370.21 KIK67017.1 - 1.6e-18 67.1 0.0 2.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK67017.1 - 3.3e-15 55.9 0.0 5.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK67017.1 - 5.2e-11 42.8 0.1 9.2e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIK67017.1 - 8.5e-09 35.3 0.8 1.3e-08 34.6 0.0 1.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK67017.1 - 1.3e-07 31.1 0.1 5.1e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIK67017.1 - 0.00033 20.3 0.1 0.00049 19.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIK67017.1 - 0.0058 16.9 0.1 0.0099 16.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIK67017.1 - 0.0096 15.8 0.3 0.024 14.6 0.3 1.6 1 1 0 1 1 1 1 KR domain Peptidase_M50 PF02163.22 KIK67017.1 - 0.068 12.4 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M50 NAD_binding_4 PF07993.12 KIK67018.1 - 3.7e-32 111.5 0.0 5.4e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK67018.1 - 3e-27 95.3 0.0 7.7e-27 93.9 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIK67018.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK67018.1 - 9.1e-05 22.7 0.2 0.00041 20.6 0.2 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KIK67018.1 - 0.023 14.6 0.0 0.078 12.9 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 KIK67019.1 - 6.3e-55 186.7 0.0 1.4e-54 185.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 4HBT_3 PF13622.6 KIK67020.1 - 0.034 14.4 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Nup84_Nup100 PF04121.13 KIK67022.1 - 5.2e-168 560.4 0.6 6e-168 560.2 0.6 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.14 KIK67022.1 - 0.0059 15.1 0.1 0.01 14.4 0.1 1.3 1 0 0 1 1 1 1 Nup93/Nic96 TPR_14 PF13428.6 KIK67022.1 - 1.2 10.2 7.4 0.48 11.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PepSY_TM PF03929.16 KIK67024.1 - 0.002 17.9 0.1 0.0052 16.5 0.0 1.7 2 0 0 2 2 2 1 PepSY-associated TM region DUF2207 PF09972.9 KIK67024.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 KIK67024.1 - 0.038 14.1 0.7 0.038 14.1 0.7 3.0 3 0 0 3 3 3 0 Podoplanin Lipase_3 PF01764.25 KIK67025.1 - 8.1e-33 113.3 0.1 1.1e-32 112.9 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK67025.1 - 0.0031 18.2 0.1 0.0093 16.6 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KIK67025.1 - 0.0037 16.9 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 KIK67025.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KIK67025.1 - 0.0085 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DHquinase_I PF01487.15 KIK67025.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase ABC_tran PF00005.27 KIK67026.1 - 5.2e-34 117.7 0.0 1e-33 116.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIK67026.1 - 2.3e-33 116.0 12.3 3.8e-33 115.3 12.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KIK67026.1 - 0.00012 21.7 0.2 0.0016 17.9 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK67026.1 - 0.0013 18.6 0.2 0.0042 16.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIK67026.1 - 0.0068 16.7 0.0 0.05 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK67026.1 - 0.0075 16.0 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK67026.1 - 0.0078 16.6 0.3 0.029 14.7 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 KIK67026.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIK67026.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 KIK67026.1 - 0.039 12.9 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 KIK67026.1 - 0.087 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KIK67026.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KIK67026.1 - 0.17 11.9 0.1 4.3 7.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) RRM_1 PF00076.22 KIK67027.1 - 7.4e-23 80.2 0.0 9.5e-23 79.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK67027.1 - 0.03 14.4 0.0 0.042 14.0 0.0 1.3 1 1 0 1 1 1 0 RNA recognition motif HMG_box PF00505.19 KIK67028.1 - 1.1e-19 70.6 1.4 1.3e-19 70.3 1.4 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK67028.1 - 3.3e-09 37.2 0.8 3.9e-09 37.0 0.8 1.1 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 KIK67029.1 - 6e-61 206.1 0.0 8.1e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67029.1 - 5.3e-33 114.4 0.0 7.9e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK67029.1 - 1.2e-08 34.7 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KIK67029.1 - 0.0012 18.5 0.0 0.75 9.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK67029.1 - 0.0023 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK67029.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ALS_ss_C PF10369.9 KIK67030.1 - 1.1e-18 67.1 0.2 3.6e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KIK67030.1 - 2.1e-13 49.8 0.1 3.9e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KIK67030.1 - 7.3e-07 28.9 0.0 2.4e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 ACT domain DUF2187 PF09953.9 KIK67030.1 - 0.017 15.1 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) COG5 PF10392.9 KIK67031.1 - 1.2e-26 93.4 1.1 1.2e-26 93.4 1.1 3.4 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KIK67031.1 - 0.00012 22.1 0.3 0.00096 19.2 0.3 2.7 1 1 0 1 1 1 1 Vps51/Vps67 Occludin_ELL PF07303.13 KIK67031.1 - 0.015 16.0 0.2 0.14 12.9 0.1 2.6 2 0 0 2 2 2 0 Occludin homology domain Laminin_II PF06009.12 KIK67031.1 - 0.078 13.0 3.5 0.092 12.8 0.9 2.5 2 0 0 2 2 2 0 Laminin Domain II COG2 PF06148.11 KIK67031.1 - 0.085 12.9 4.1 0.097 12.8 0.3 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KIK67031.1 - 0.28 11.2 1.8 0.79 9.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 KIK67031.1 - 1.3 9.6 5.4 0.97 10.0 0.9 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KIK67031.1 - 1.8 8.6 13.4 0.11 12.5 0.7 4.1 3 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KIK67031.1 - 4 7.6 6.8 7.5 6.7 0.3 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Fungal_trans PF04082.18 KIK67032.1 - 6.2e-18 64.8 1.6 1.2e-17 63.8 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK67032.1 - 2.4e-05 24.3 7.2 4.8e-05 23.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KIK67033.1 - 2.9e-67 227.7 0.0 3.6e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK67033.1 - 1.4e-06 28.3 0.0 0.00034 20.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3759 PF12585.8 KIK67034.1 - 0.004 17.2 0.2 0.008 16.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Tetraspanin PF00335.20 KIK67035.1 - 0.00031 20.6 4.6 0.00031 20.6 4.6 1.5 1 1 0 1 1 1 1 Tetraspanin family ABC2_membrane_3 PF12698.7 KIK67035.1 - 0.0017 17.5 5.0 0.0017 17.5 5.0 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF3421 PF11901.8 KIK67036.1 - 6.1e-30 103.6 0.1 8.3e-25 87.0 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) MPC PF03650.13 KIK67037.1 - 3.2e-40 136.7 0.1 3.7e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF5572 PF17733.1 KIK67038.1 - 0.06 13.2 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5572) CbiQ PF02361.16 KIK67038.1 - 0.96 9.0 6.8 1.4 8.5 6.8 1.1 1 0 0 1 1 1 0 Cobalt transport protein IPTL-CTERM PF18203.1 KIK67038.1 - 8.1 6.5 8.1 20 5.2 1.0 2.7 2 0 0 2 2 2 0 IPTL-CTERM motif RPA_interact_C PF14768.6 KIK67039.1 - 0.021 15.4 0.1 0.03 14.9 0.1 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal DUF4452 PF14618.6 KIK67039.1 - 0.046 13.6 5.1 0.058 13.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Sugar_tr PF00083.24 KIK67040.1 - 3.7e-93 312.9 22.2 4.5e-93 312.6 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK67040.1 - 2.6e-18 66.1 48.2 4.8e-11 42.2 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK67041.1 - 1.1e-89 301.4 21.0 1.4e-89 301.0 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK67041.1 - 4.7e-21 75.1 57.9 1.1e-19 70.6 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MT-A70 PF05063.14 KIK67042.1 - 3.2e-55 186.7 0.2 4.1e-37 127.8 0.1 2.2 2 0 0 2 2 2 2 MT-A70 WD40 PF00400.32 KIK67043.1 - 2.7e-05 24.8 0.0 0.74 10.8 0.0 4.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK67043.1 - 0.0008 19.7 0.0 4.2 7.7 0.0 4.4 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Arf PF00025.21 KIK67044.1 - 2.7e-77 258.1 0.0 3.1e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK67044.1 - 3.2e-15 56.4 0.0 4.3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK67044.1 - 9e-13 48.1 0.0 9.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KIK67044.1 - 3.5e-11 42.9 1.0 9.4e-07 28.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIK67044.1 - 5.6e-11 42.2 0.0 7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK67044.1 - 4.8e-09 35.9 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK67044.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIK67044.1 - 0.019 14.3 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PALP PF00291.25 KIK67045.1 - 4e-70 236.5 0.8 4.6e-70 236.4 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NIF PF03031.18 KIK67046.1 - 2.5e-54 183.3 0.0 2.9e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIK67046.1 - 0.014 15.8 0.0 0.16 12.3 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 KIK67050.1 - 3.6e-10 39.9 9.9 0.00027 21.3 0.3 4.9 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK67050.1 - 2.1e-09 37.0 11.4 8.4e-06 25.5 4.2 4.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KIK67050.1 - 0.0089 16.0 4.5 3.5 7.9 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KIK67050.1 - 0.22 12.2 9.3 1.2e+02 3.9 0.2 5.9 4 1 0 4 4 4 0 Leucine Rich Repeat UBA PF00627.31 KIK67051.1 - 8.2e-30 102.3 2.8 5.2e-14 51.8 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KIK67051.1 - 3.1e-21 74.9 0.1 5.2e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KIK67051.1 - 2.8e-17 62.2 10.3 2.8e-17 62.2 10.3 1.9 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 KIK67051.1 - 3.8e-05 23.4 0.5 6.1e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KIK67051.1 - 0.00099 18.9 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 KIK67051.1 - 0.0033 17.7 0.1 0.0061 16.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK67051.1 - 0.0039 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2076 PF09849.9 KIK67051.1 - 0.006 16.7 0.7 0.006 16.7 0.7 3.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) Ubiquitin_2 PF14560.6 KIK67051.1 - 0.018 15.5 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 KIK67051.1 - 0.035 13.8 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 CUE domain DUF1269 PF06897.12 KIK67051.1 - 0.045 14.0 1.5 0.2 11.9 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) WIYLD PF10440.9 KIK67051.1 - 0.068 13.0 0.1 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain TFIIA PF03153.13 KIK67051.1 - 3.3 7.6 13.9 4.7 7.1 13.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3419 PF11899.8 KIK67052.1 - 3.6e-143 477.4 0.0 4.6e-143 477.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KIK67052.1 - 5.3e-09 36.1 0.0 1.5e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK67052.1 - 3e-07 31.1 0.0 2.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK67052.1 - 1.2e-05 25.8 0.0 0.00014 22.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK67052.1 - 3.3e-05 24.6 0.0 0.00072 20.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK67052.1 - 5.3e-05 22.7 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK67052.1 - 9.5e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIK67052.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RFC1 PF08519.12 KIK67053.1 - 2.4e-58 196.8 0.0 3.8e-56 189.6 0.0 2.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KIK67053.1 - 2.1e-15 56.8 0.0 6.1e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KIK67053.1 - 2.5e-08 34.4 1.1 7.6e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK67053.1 - 0.00062 19.7 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KIK67053.1 - 0.015 15.1 0.0 0.07 12.9 0.0 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KIK67053.1 - 0.024 14.4 0.7 0.094 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF4413 PF14372.6 KIK67053.1 - 0.049 14.0 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) AAA_16 PF13191.6 KIK67053.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KIK67053.1 - 0.074 13.4 0.0 0.37 11.2 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_assoc_2 PF16193.5 KIK67053.1 - 0.097 13.0 0.0 0.39 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 KIK67053.1 - 0.11 12.6 0.1 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain CCDC-167 PF15188.6 KIK67053.1 - 0.93 9.9 4.5 1.2 9.6 2.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RhoGAP PF00620.27 KIK67054.1 - 3.2e-42 143.9 0.1 8.6e-42 142.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KIK67054.1 - 4.1e-11 42.9 19.9 1.3e-07 31.7 8.4 3.1 3 0 0 3 3 2 2 LIM domain C1_1 PF00130.22 KIK67054.1 - 7.6e-06 25.7 7.7 7.6e-06 25.7 7.7 3.8 2 1 2 4 4 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIK67054.1 - 0.004 17.4 1.5 0.004 17.4 1.5 3.8 3 1 1 4 4 4 1 C1 domain Cytochrom_C552 PF02335.15 KIK67054.1 - 0.33 9.8 5.1 0.6 9.0 5.1 1.3 1 0 0 1 1 1 0 Cytochrome c552 Gp-FAR-1 PF05823.12 KIK67054.1 - 0.38 11.1 2.7 0.37 11.1 0.2 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PI3K_P85_iSH2 PF16454.5 KIK67054.1 - 0.43 10.2 7.6 0.91 9.1 1.2 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cep57_MT_bd PF06657.13 KIK67054.1 - 0.66 10.5 5.0 20 5.7 1.5 4.0 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 YlqD PF11068.8 KIK67054.1 - 2.1 8.8 8.1 0.1 12.9 0.4 2.6 2 1 1 3 3 3 0 YlqD protein HALZ PF02183.18 KIK67054.1 - 2.1 8.6 7.8 0.24 11.6 0.9 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2685 PF10886.8 KIK67054.1 - 3.5 7.9 5.8 13 6.1 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2685) KTI12 PF08433.10 KIK67055.1 - 2e-71 240.7 0.0 2.2e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KIK67055.1 - 2.1e-09 37.7 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KIK67055.1 - 0.085 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AMP-binding PF00501.28 KIK67057.1 - 2.4e-21 75.8 0.0 2.1e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KIK67057.1 - 0.00025 20.0 0.0 0.00054 19.0 0.0 1.6 2 0 0 2 2 2 1 GH3 auxin-responsive promoter AMP-binding PF00501.28 KIK67058.1 - 1.9e-85 287.0 0.0 2.4e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK67058.1 - 8e-12 46.0 0.0 1.6e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAM209 PF15206.6 KIK67059.1 - 0.0045 16.8 0.2 0.35 10.7 0.0 2.5 2 0 0 2 2 2 1 FAM209 family NOPS PF08075.11 KIK67059.1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 NOPS (NUC059) domain Spore_III_AB PF09548.10 KIK67059.1 - 1.7 8.8 5.0 5 7.2 5.0 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) bZIP_2 PF07716.15 KIK67059.1 - 8.4 6.6 20.8 0.28 11.3 2.7 4.0 4 0 0 4 4 4 0 Basic region leucine zipper TMPIT PF07851.13 KIK67059.1 - 9.3 5.4 6.1 19 4.4 6.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein KIAA1430 PF13879.6 KIK67059.1 - 10 7.0 20.5 16 6.3 12.7 3.0 1 1 1 2 2 2 0 KIAA1430 homologue FMN_bind_2 PF04299.12 KIK67060.1 - 2.2e-58 196.7 0.1 2.6e-58 196.4 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Dynein_AAA_lid PF17852.1 KIK67061.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain PC-Esterase PF13839.6 KIK67062.1 - 3.5e-11 43.4 4.4 2e-09 37.6 4.7 2.8 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Pam16 PF03656.13 KIK67063.1 - 3.7e-18 65.8 4.9 1.7e-12 47.5 1.3 2.4 2 1 0 2 2 2 2 Pam16 BNIP3 PF06553.12 KIK67063.1 - 0.51 10.0 3.1 1.6 8.4 2.1 1.7 1 1 1 2 2 2 0 BNIP3 RPA43_OB PF17875.1 KIK67064.1 - 8.9e-26 90.9 0.0 8.9e-26 90.9 0.0 3.2 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KIK67064.1 - 7.9e-06 26.2 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF678 PF05077.12 KIK67064.1 - 2.8 8.1 4.9 6.3 7.0 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) BIR PF00653.21 KIK67065.1 - 4.2e-36 123.5 4.6 4.3e-17 62.5 0.2 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KIK67065.1 - 0.0024 17.9 0.2 1.7 8.7 0.0 2.8 2 0 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.15 KIK67065.1 - 0.0055 16.7 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 2 BED zinc finger HMMR_C PF15908.5 KIK67066.1 - 6.3e-07 29.8 3.0 6.3e-07 29.8 3.0 5.5 2 2 2 4 4 4 1 Hyaluronan mediated motility receptor C-terminal Lebercilin PF15619.6 KIK67066.1 - 0.0045 16.7 3.1 0.0045 16.7 3.1 5.9 2 2 2 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease DUF4172 PF13776.6 KIK67066.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4172) HALZ PF02183.18 KIK67066.1 - 1.9 8.8 30.6 6.7 7.0 1.1 8.1 7 1 2 9 9 9 0 Homeobox associated leucine zipper CALCOCO1 PF07888.11 KIK67066.1 - 3 6.6 75.8 1.5 7.6 29.7 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Polysacc_deac_1 PF01522.21 KIK67067.1 - 1.5e-28 99.2 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Pox_A12 PF04651.13 KIK67067.1 - 0.36 10.9 2.1 0.37 10.8 0.2 1.9 3 0 0 3 3 3 0 Poxvirus A12 protein Polysacc_deac_1 PF01522.21 KIK67068.1 - 8.4e-29 100.0 0.0 1.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase PLA2_B PF01735.18 KIK67069.1 - 3.9e-98 329.0 0.2 5.2e-98 328.6 0.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain stn_TNFRSF12A PF12191.8 KIK67069.1 - 0.055 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SKG6 PF08693.10 KIK67069.1 - 0.18 11.2 5.8 0.35 10.3 5.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OppC_N PF12911.7 KIK67072.1 - 0.017 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2207 PF09972.9 KIK67072.1 - 0.037 12.8 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1771 PF08590.10 KIK67073.1 - 1.9e-25 89.0 6.6 4e-25 88.0 6.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KIK67073.1 - 1.9e-11 44.1 0.5 4.3e-11 43.0 0.5 1.5 1 0 0 1 1 1 1 Smr domain TFIIA PF03153.13 KIK67073.1 - 0.029 14.4 12.7 0.036 14.1 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF908 PF06012.12 KIK67073.1 - 2.2 7.6 5.0 2.7 7.3 5.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4482 PF14818.6 KIK67073.1 - 4 8.3 6.8 2.3 9.1 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) ODC_AZ PF02100.17 KIK67074.1 - 1.1e-15 57.6 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.20 KIK67075.1 - 1.3e-28 98.8 0.6 1.3e-28 98.8 0.6 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KIK67075.1 - 8e-24 82.9 0.1 1.4e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.22 KIK67077.1 - 4.3e-69 233.5 0.1 1.5e-67 228.3 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 KIK67078.1 - 2.2e-13 50.1 0.3 4e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain WxL PF13731.6 KIK67079.1 - 0.042 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 WxL domain surface cell wall-binding Peptidase_C1_2 PF03051.15 KIK67080.1 - 5.5e-159 529.6 0.0 6.3e-159 529.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KIK67080.1 - 1.2e-07 32.1 0.0 0.017 15.2 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease Phage_portal_2 PF05136.13 KIK67080.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family DUF5308 PF17233.2 KIK67081.1 - 0.00093 19.5 1.8 0.0011 19.3 1.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5308) RPEL PF02755.15 KIK67082.1 - 7.2e-11 41.4 7.1 5.6e-06 25.9 1.0 2.8 2 1 0 2 2 2 2 RPEL repeat DUF1279 PF06916.13 KIK67083.1 - 3e-16 59.8 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SAM_decarbox PF01536.16 KIK67084.1 - 1.6e-118 395.8 0.0 1e-117 393.1 0.0 1.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Zn_clus PF00172.18 KIK67085.1 - 2.8e-07 30.5 28.3 0.0019 18.3 12.7 2.7 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 KIK67086.1 - 4.9e-64 216.0 0.0 6.3e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Dfp1_Him1_M PF08630.10 KIK67087.1 - 3e-27 95.3 0.3 8.9e-27 93.8 0.0 2.0 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KIK67087.1 - 1.5e-17 63.4 0.1 2.9e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KIK67087.1 - 0.00028 20.8 0.1 0.00086 19.2 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KIK67087.1 - 0.0043 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain tRNA-synt_1g PF09334.11 KIK67088.1 - 5.2e-91 305.3 0.0 6.5e-90 301.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIK67088.1 - 1.3e-23 83.1 0.1 7.1e-12 44.4 0.0 4.0 1 1 3 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KIK67088.1 - 4.3e-09 36.1 0.1 0.0015 18.0 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Dynamitin PF04912.14 KIK67089.1 - 1.1e-61 209.4 10.2 1.4e-61 209.0 10.2 1.1 1 0 0 1 1 1 1 Dynamitin TPR_MLP1_2 PF07926.12 KIK67089.1 - 0.00091 19.3 2.0 0.00091 19.3 2.0 3.1 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KIK67089.1 - 0.0051 16.9 4.9 0.31 11.1 0.3 3.3 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KIK67089.1 - 0.011 15.8 1.2 0.011 15.8 1.2 3.0 2 2 0 3 3 3 0 Laminin Domain II YPEB PF14620.6 KIK67089.1 - 0.012 15.0 0.6 0.043 13.2 0.3 2.0 2 0 0 2 2 2 0 YpeB sporulation Spc7 PF08317.11 KIK67089.1 - 0.012 14.5 0.9 0.012 14.5 0.9 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KIK67089.1 - 0.013 15.4 4.6 0.14 12.1 2.2 3.1 2 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 KIK67089.1 - 0.014 15.4 0.9 0.071 13.1 0.1 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KIK67089.1 - 0.014 15.3 2.1 0.014 15.3 2.1 2.7 4 0 0 4 4 3 0 Apolipoprotein A1/A4/E domain Tropomyosin_1 PF12718.7 KIK67089.1 - 0.021 15.0 10.2 0.95 9.6 2.8 3.8 4 0 0 4 4 3 0 Tropomyosin like Mce4_CUP1 PF11887.8 KIK67089.1 - 0.041 13.3 0.2 0.1 12.0 0.1 1.7 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Cep57_MT_bd PF06657.13 KIK67089.1 - 0.041 14.3 2.1 3.5 8.1 0.3 2.9 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 RmuC PF02646.16 KIK67089.1 - 0.042 13.0 0.4 0.12 11.5 0.2 1.8 2 0 0 2 2 2 0 RmuC family EzrA PF06160.12 KIK67089.1 - 0.043 12.0 3.0 0.051 11.8 0.5 2.2 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KIK67089.1 - 0.044 14.0 5.0 1.7 8.9 0.2 3.6 4 1 0 4 4 3 0 ABC transporter C-terminal domain COG2 PF06148.11 KIK67089.1 - 0.083 13.0 6.9 0.21 11.7 0.8 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ANAPC4 PF12896.7 KIK67089.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Spc24 PF08286.11 KIK67089.1 - 0.13 12.5 7.0 0.49 10.7 1.0 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF1411 PF07199.11 KIK67089.1 - 0.14 11.8 0.1 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Fib_alpha PF08702.10 KIK67089.1 - 0.21 11.8 2.9 0.31 11.2 0.1 2.7 4 0 0 4 4 3 0 Fibrinogen alpha/beta chain family Corona_S2 PF01601.16 KIK67089.1 - 0.22 10.0 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TACC_C PF05010.14 KIK67089.1 - 0.22 11.3 4.2 0.64 9.8 0.7 2.7 3 0 0 3 3 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DASH_Hsk3 PF08227.11 KIK67089.1 - 0.29 11.5 4.4 12 6.3 0.2 3.0 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF2205 PF10224.9 KIK67089.1 - 0.31 11.1 6.6 21 5.2 0.3 4.1 3 1 1 4 4 4 0 Short coiled-coil protein Swi5 PF07061.11 KIK67089.1 - 0.38 10.9 2.3 24 5.1 0.3 2.9 2 0 0 2 2 2 0 Swi5 AIP3 PF03915.13 KIK67089.1 - 0.49 9.4 7.8 0.012 14.8 1.1 1.7 3 0 0 3 3 2 0 Actin interacting protein 3 Syntaxin-6_N PF09177.11 KIK67089.1 - 0.65 10.6 9.0 0.33 11.5 1.1 3.7 3 1 1 4 4 4 0 Syntaxin 6, N-terminal CENP-H PF05837.12 KIK67089.1 - 0.94 9.9 4.4 2.2 8.7 0.5 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.13 KIK67089.1 - 1 10.1 2.8 4.3 8.1 0.1 3.0 3 0 0 3 3 3 0 Occludin homology domain FlaC_arch PF05377.11 KIK67089.1 - 1.1 9.8 6.6 4.1 7.9 1.5 3.9 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 KIK67089.1 - 1.3 9.0 12.9 2.8 8.0 2.8 3.8 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KIK67089.1 - 1.3 8.3 3.9 26 4.1 0.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KIK67089.1 - 1.5 8.1 8.6 0.079 12.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 KIK67089.1 - 1.7 8.3 8.6 0.52 9.9 1.0 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HSBP1 PF06825.12 KIK67089.1 - 2.2 8.2 9.9 2.9 7.8 0.1 3.6 5 0 0 5 5 2 0 Heat shock factor binding protein 1 DUF4164 PF13747.6 KIK67089.1 - 2.6 8.4 7.1 1.1 9.5 0.1 3.6 4 1 0 4 4 3 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 KIK67089.1 - 6 7.4 15.1 2 9.0 3.6 3.1 2 2 1 3 3 3 0 Apg6 coiled-coil region Con-6 PF10346.9 KIK67090.1 - 0.00069 19.6 0.9 0.0014 18.6 0.3 1.8 2 0 0 2 2 2 1 Conidiation protein 6 PLN_propep PF16485.5 KIK67090.1 - 5 6.9 5.7 5.7 6.7 1.0 2.3 2 0 0 2 2 2 0 Protealysin propeptide Med27 PF11571.8 KIK67091.1 - 7.4e-11 42.3 1.3 1.5e-10 41.3 0.4 1.9 2 0 0 2 2 2 1 Mediator complex subunit 27 SesA PF17107.5 KIK67091.1 - 0.0054 16.9 0.2 0.0095 16.1 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases zinc_ribbon_12 PF11331.8 KIK67091.1 - 0.11 12.3 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain YABBY PF04690.13 KIK67091.1 - 0.15 12.6 2.8 8.7 6.9 0.1 2.6 2 1 1 3 3 3 0 YABBY protein DOCK_N PF16172.5 KIK67093.1 - 2.2e-114 382.3 0.0 3.5e-114 381.6 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KIK67093.1 - 4.4e-72 243.4 0.3 1.4e-71 241.8 0.3 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KIK67093.1 - 4e-53 180.1 0.0 1.5e-51 175.0 0.0 2.9 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins DASH_Spc34 PF08657.10 KIK67094.1 - 0.00053 19.9 3.9 0.037 13.8 0.0 2.2 1 1 0 2 2 2 1 DASH complex subunit Spc34 DegV PF02645.16 KIK67094.1 - 0.11 11.8 0.9 0.29 10.4 0.7 1.7 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 UPF0242 PF06785.11 KIK67094.1 - 0.38 10.8 4.8 0.63 10.1 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Asparaginase_2 PF01112.18 KIK67095.1 - 1.6e-74 250.7 0.0 9.7e-55 185.7 0.0 2.3 2 1 0 2 2 2 2 Asparaginase Tho1_MOS11_C PF18592.1 KIK67096.1 - 4.3e-06 26.4 4.3 0.1 12.4 1.8 3.2 2 1 0 2 2 2 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 KIK67096.1 - 7.8e-06 25.5 1.8 1.5e-05 24.6 1.8 1.5 1 0 0 1 1 1 1 HeH/LEM domain Rho_N PF07498.12 KIK67096.1 - 0.0014 18.5 0.9 0.0038 17.1 0.3 2.0 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain SAP PF02037.27 KIK67096.1 - 0.0044 16.7 2.4 0.012 15.3 0.3 2.5 2 0 0 2 2 2 1 SAP domain Mac PF12464.8 KIK67096.1 - 0.84 9.9 2.7 3.8 7.8 0.1 2.7 3 0 0 3 3 3 0 Maltose acetyltransferase CBFB_NFYA PF02045.15 KIK67097.1 - 6.3e-29 100.4 7.2 7.3e-29 100.2 7.2 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ICMT PF04140.14 KIK67099.1 - 2.4e-15 56.7 2.4 1.4e-13 51.1 0.1 2.7 3 0 0 3 3 3 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK67099.1 - 2.1e-11 44.1 0.4 1.6e-10 41.3 0.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK67099.1 - 7.8e-06 24.9 0.1 1.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UPF0126 PF03458.13 KIK67099.1 - 0.38 10.7 5.0 0.51 10.3 3.1 2.2 1 1 1 2 2 2 0 UPF0126 domain OSCP PF00213.18 KIK67100.1 - 5.7e-42 143.8 2.9 6.6e-42 143.5 2.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF765 PF05570.11 KIK67100.1 - 0.037 14.2 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) TRP PF06011.12 KIK67101.1 - 6.2e-77 259.1 30.5 8.6e-77 258.7 30.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KIK67101.1 - 6.9e-29 101.0 1.1 1.2e-28 100.2 1.1 1.4 1 0 0 1 1 1 1 ML-like domain EB PF01683.18 KIK67102.1 - 0.0094 16.2 24.3 0.094 13.0 1.4 4.2 2 1 1 3 3 3 2 EB module Dickkopf_N PF04706.12 KIK67102.1 - 0.45 11.0 32.4 0.11 12.9 7.5 4.4 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Na_H_Exchanger PF00999.21 KIK67104.1 - 7.7e-59 199.4 24.7 9.6e-59 199.1 24.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_8 PF16931.5 KIK67104.1 - 0.015 15.3 1.3 0.75 9.8 1.9 3.1 2 1 0 3 3 3 0 Putative phage holin DUF2071 PF09844.9 KIK67105.1 - 0.0024 17.5 0.2 0.0029 17.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (COG2071) Rax2 PF12768.7 KIK67106.1 - 8.9e-47 159.3 14.3 1.2e-42 145.8 1.2 5.7 4 1 1 5 5 5 3 Cortical protein marker for cell polarity SH3_1 PF00018.28 KIK67106.1 - 8.3e-11 41.3 0.0 1.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK67106.1 - 7.8e-08 32.1 0.4 1.7e-07 31.0 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain EphA2_TM PF14575.6 KIK67106.1 - 0.13 13.2 0.0 2.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5122 PF17164.4 KIK67106.1 - 0.65 10.3 23.6 1.4 9.3 0.0 8.3 9 0 0 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller Kelch_1 PF01344.25 KIK67106.1 - 1.5 8.4 5.1 7.9 6.2 0.2 4.4 6 0 0 6 6 6 0 Kelch motif zf-C2H2_2 PF12756.7 KIK67107.1 - 4.7e-36 123.2 10.3 2.3e-29 101.7 0.2 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KIK67107.1 - 4.1e-10 39.7 18.5 2.8e-09 37.0 4.2 3.6 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK67107.1 - 1.8e-09 37.6 3.9 1.8e-09 37.6 3.9 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK67107.1 - 9.7e-05 22.9 14.4 0.03 15.2 0.3 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK67107.1 - 0.0037 17.2 9.9 0.016 15.2 1.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK67107.1 - 0.031 14.8 12.5 0.12 12.9 0.9 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type AKAP95 PF04988.12 KIK67107.1 - 0.11 12.7 5.8 4.4 7.5 0.0 3.0 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF629 PF04780.12 KIK67107.1 - 0.17 10.4 5.8 1.3 7.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF629) Rtf2 PF04641.12 KIK67107.1 - 0.23 10.8 7.7 0.039 13.3 3.6 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger zf-LYAR PF08790.11 KIK67107.1 - 0.29 11.1 2.2 7.5 6.6 0.2 2.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HC5 PF06221.13 KIK67107.1 - 3.9 7.5 6.5 9.2 6.4 0.1 3.4 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type Pox_RNA_Pol_19 PF05320.12 KIK67107.1 - 4.8 7.1 8.5 0.29 11.1 0.1 2.4 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Pex24p PF06398.11 KIK67108.1 - 4.5e-36 124.6 8.8 9.4e-36 123.6 8.8 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Mannosyl_trans2 PF04188.13 KIK67109.1 - 2e-39 136.2 34.7 6.2e-35 121.4 20.7 3.3 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) Amidohydro_2 PF04909.14 KIK67110.1 - 3.8e-32 112.2 0.0 4.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase bZIP_1 PF00170.21 KIK67111.1 - 1.5 9.0 12.3 0.15 12.2 7.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor Chitin_synth_1 PF01644.17 KIK67113.1 - 3.8e-75 251.3 0.2 9.9e-75 250.0 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK67113.1 - 4.1e-26 90.7 0.1 9.2e-26 89.6 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK67113.1 - 4e-21 75.2 5.3 1.5e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK67113.1 - 2.8e-05 24.1 0.0 2.8e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF5134 PF17197.4 KIK67113.1 - 0.051 13.5 1.8 0.096 12.6 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) PPR_2 PF13041.6 KIK67115.1 - 2.6e-32 110.8 1.1 5.9e-10 39.2 0.0 8.3 5 3 3 8 8 8 7 PPR repeat family PPR_3 PF13812.6 KIK67115.1 - 2.2e-31 107.7 0.6 6.7e-10 38.9 0.0 6.3 4 3 4 8 8 8 6 Pentatricopeptide repeat domain PPR_long PF17177.4 KIK67115.1 - 2.2e-21 76.2 0.0 1e-08 34.8 0.0 3.8 2 2 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KIK67115.1 - 1.7e-12 46.8 0.1 0.002 17.8 0.0 6.6 8 0 0 8 8 8 3 PPR repeat PPR PF01535.20 KIK67115.1 - 9.8e-12 44.3 5.7 0.084 13.2 0.0 7.8 10 0 0 10 10 10 3 PPR repeat ECSIT PF06239.11 KIK67115.1 - 0.019 14.1 0.0 8.5 5.4 0.0 3.4 2 1 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.7 KIK67115.1 - 0.025 14.5 0.0 1.1 9.2 0.0 3.3 3 1 0 3 3 3 0 Mitochondrial ATPase expression Phage_ABA_S PF18066.1 KIK67115.1 - 0.07 13.8 0.0 9 7.1 0.0 3.2 2 1 1 3 3 3 0 Phage ABA sandwich domain Rad21_Rec8_N PF04825.13 KIK67116.1 - 9.3e-36 122.3 0.3 1.9e-35 121.3 0.3 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIK67116.1 - 8.6e-14 50.6 0.0 1.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Melibiase_2 PF16499.5 KIK67117.1 - 1.3e-53 182.0 1.7 2.2e-53 181.3 1.7 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIK67117.1 - 8.3e-15 54.6 0.2 5.5e-13 48.8 0.1 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIK67117.1 - 7.4e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Melibiase PBP PF01161.20 KIK67118.1 - 3e-14 53.4 0.2 7.9e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CMD PF02627.20 KIK67119.1 - 3.3e-07 30.3 0.0 3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Glyco_hydro_16 PF00722.21 KIK67120.1 - 0.041 13.4 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DUF2236 PF09995.9 KIK67121.1 - 1.6e-29 103.7 1.0 2.3e-29 103.2 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) CCT PF06203.14 KIK67122.1 - 0.11 12.6 0.5 0.18 11.9 0.5 1.2 1 0 0 1 1 1 0 CCT motif CbtA PF09490.10 KIK67122.1 - 1.2 8.9 6.2 20 4.8 0.1 2.7 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) PTPLA PF04387.14 KIK67123.1 - 8.9e-58 194.7 12.3 1.7e-57 193.7 12.3 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA F-box-like PF12937.7 KIK67124.1 - 1.6e-06 27.9 0.1 5.8e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK67124.1 - 0.76 10.3 8.2 0.5 10.9 0.3 4.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Cu-oxidase PF00394.22 KIK67125.1 - 4.6e-48 163.3 0.0 6.8e-46 156.3 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK67125.1 - 1.7e-36 125.0 2.2 8.3e-33 113.0 0.0 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK67125.1 - 1.7e-31 108.7 0.0 6.6e-29 100.3 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Ribosomal_S7 PF00177.21 KIK67126.1 - 8.5e-26 90.4 0.0 9.8e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NIF PF03031.18 KIK67127.1 - 6.5e-53 178.7 0.0 8.6e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIK67127.1 - 0.037 14.4 0.1 0.32 11.4 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Smr PF01713.21 KIK67129.1 - 1.3e-09 38.3 0.1 2.7e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Smr domain zf-U1 PF06220.12 KIK67131.1 - 5e-10 39.0 2.5 7.9e-10 38.4 2.5 1.3 1 0 0 1 1 1 1 U1 zinc finger Sds3 PF08598.11 KIK67131.1 - 0.075 13.0 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Sds3-like zf-TRM13_CCCH PF11722.8 KIK67131.1 - 0.28 11.0 4.4 0.59 9.9 4.4 1.6 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein MFS_1 PF07690.16 KIK67132.1 - 1.9e-15 56.7 34.8 2.8e-15 56.1 34.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KIK67132.1 - 0.0017 16.7 0.1 0.0017 16.7 0.1 2.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family UPF0020 PF01170.18 KIK67133.1 - 4.3e-09 36.3 0.0 1.4e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KIK67133.1 - 0.00016 21.5 0.0 0.25 11.0 0.0 2.4 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 KIK67133.1 - 0.0022 17.4 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase VGCC_alpha2 PF08473.11 KIK67133.1 - 0.047 12.5 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd DUF43 PF01861.16 KIK67133.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain TPR_19 PF14559.6 KIK67134.1 - 1.4e-15 57.5 18.3 0.011 16.2 0.3 8.8 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67134.1 - 2.3e-15 55.4 15.5 0.0065 16.5 0.2 10.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK67134.1 - 2.3e-11 43.5 19.4 0.89 10.5 0.4 9.5 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK67134.1 - 1.8e-10 41.0 15.1 0.4 11.0 0.0 10.0 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK67134.1 - 4.3e-10 40.1 16.6 0.011 16.4 1.0 7.0 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK67134.1 - 5.2e-10 38.7 8.2 0.91 9.5 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK67134.1 - 3.4e-09 36.2 1.7 0.004 16.8 0.0 6.3 6 0 0 6 6 6 1 TPR repeat TPR_6 PF13174.6 KIK67134.1 - 3.3e-08 33.6 11.7 1.3 9.8 0.0 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK67134.1 - 5.5e-08 32.4 13.9 0.87 10.0 0.0 9.0 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK67134.1 - 6e-07 29.4 6.4 0.37 11.3 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK67134.1 - 2.9e-06 26.9 11.8 0.35 11.0 0.0 6.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 KIK67134.1 - 5.4e-05 23.4 1.9 0.055 13.8 0.3 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIK67134.1 - 0.001 19.5 3.9 0.96 9.9 0.1 4.1 4 1 0 4 4 3 1 Alkyl sulfatase dimerisation ChAPs PF09295.10 KIK67134.1 - 0.0035 16.4 0.1 0.93 8.4 0.0 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 KIK67134.1 - 0.0046 17.1 15.3 3.8 7.8 0.2 7.0 7 1 1 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KIK67134.1 - 0.023 14.6 11.2 35 4.4 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Peptidase_S64 PF08192.11 KIK67134.1 - 0.27 9.7 4.8 0.48 8.9 4.8 1.4 1 0 0 1 1 1 0 Peptidase family S64 Vps39_1 PF10366.9 KIK67134.1 - 0.4 11.0 3.2 5.7 7.3 0.1 3.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_9 PF13371.6 KIK67134.1 - 0.95 9.7 14.5 0.35 11.1 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK67134.1 - 4 8.3 7.6 19 6.2 0.0 4.3 4 0 0 4 4 2 0 Tetratricopeptide repeat SWIM PF04434.17 KIK67135.1 - 5.9e-06 25.8 0.2 1.1e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-4CXXC_R1 PF10497.9 KIK67136.1 - 6.8e-07 29.4 20.1 8.5e-06 25.9 20.1 2.4 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WSD PF15613.6 KIK67136.1 - 0.0012 19.3 1.3 0.042 14.3 1.3 2.8 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF5000 PF16391.5 KIK67136.1 - 0.15 12.2 0.2 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function Pyrid_ox_like PF16242.5 KIK67137.1 - 8.5e-30 103.3 0.3 1.3e-29 102.8 0.3 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KIK67137.1 - 6.2e-10 39.1 0.0 1.7e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KIK67137.1 - 0.00066 19.4 0.2 0.00096 18.9 0.2 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain F-box-like PF12937.7 KIK67138.1 - 2.1e-07 30.7 0.0 6.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like Rad9 PF04139.13 KIK67139.1 - 8.3e-44 149.9 0.1 2.3e-42 145.2 0.1 2.1 1 1 0 1 1 1 1 Rad9 DUF2757 PF10955.8 KIK67139.1 - 0.17 12.2 0.2 0.77 10.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) adh_short_C2 PF13561.6 KIK67141.1 - 2e-54 184.6 0.7 2.5e-43 148.3 0.4 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK67141.1 - 6.5e-48 162.8 0.2 8.5e-48 162.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK67141.1 - 5.2e-14 52.5 0.0 8.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK67141.1 - 0.0028 17.5 0.3 0.0045 16.9 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KIK67141.1 - 0.023 15.4 0.0 0.041 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KIK67141.1 - 0.089 12.9 0.3 0.17 12.0 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BMFP PF04380.13 KIK67142.1 - 0.18 12.3 0.6 0.85 10.2 0.1 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity DUF3731 PF12531.8 KIK67142.1 - 0.32 10.8 5.6 0.086 12.6 0.5 2.3 2 1 1 3 3 3 0 DNA-K related protein Ank PF00023.30 KIK67143.1 - 1.1e-09 38.2 0.9 9.1e-05 22.7 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.24 KIK67143.1 - 1.3e-09 38.0 0.5 6.4e-09 35.8 0.2 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 KIK67143.1 - 5.5e-09 36.5 0.1 1.7e-08 34.9 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK67143.1 - 2.9e-08 33.3 1.8 0.0099 16.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KIK67143.1 - 3.6e-08 33.8 0.2 1.6e-07 31.7 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK67143.1 - 4.1e-07 30.2 0.4 1.8e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TIG_plexin PF17960.1 KIK67143.1 - 0.011 15.7 0.5 0.75 9.8 0.0 2.7 2 0 0 2 2 2 0 TIG domain NUP50 PF08911.11 KIK67144.1 - 1.3e-17 64.2 1.4 1.3e-17 64.2 1.4 5.2 3 2 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KIK67144.1 - 3.4e-14 53.2 0.3 6.6e-14 52.2 0.3 1.5 1 0 0 1 1 1 1 RanBP1 domain RabGAP-TBC PF00566.18 KIK67145.1 - 3.1e-52 177.3 0.0 4.1e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RraA-like PF03737.15 KIK67146.1 - 5.3e-37 127.3 0.0 6.6e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA IMS PF00817.20 KIK67147.1 - 3.1e-44 150.6 0.0 5.4e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIK67147.1 - 4.3e-14 53.2 0.2 1e-13 52.0 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KIK67147.1 - 4.4e-06 26.7 0.0 1.4e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 KIK67147.1 - 0.014 15.1 0.1 0.014 15.1 0.1 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-C2H2_9 PF16293.5 KIK67147.1 - 0.17 11.8 0.1 0.63 9.9 0.1 2.0 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 KIK67147.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Peptidase_C14 PF00656.22 KIK67148.1 - 2.3e-23 83.4 0.0 3.7e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain FlgT_C PF16538.5 KIK67148.1 - 0.0021 18.6 0.1 0.009 16.5 0.1 2.1 1 1 0 1 1 1 1 Flagellar assembly protein T, C-terminal domain DUF218 PF02698.17 KIK67148.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain APG6 PF04111.12 KIK67149.1 - 4.9e-70 235.1 0.0 7.2e-70 234.6 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KIK67149.1 - 1.6e-26 93.4 21.2 1.6e-26 93.4 21.2 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region GCS PF03074.16 KIK67150.1 - 2.2e-171 570.2 0.0 2.8e-171 569.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KIK67150.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) ATP-synt_DE_N PF02823.16 KIK67151.1 - 2.4e-16 59.4 0.1 3.5e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HypD PF01924.16 KIK67151.1 - 0.087 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family 2OG-FeII_Oxy_2 PF13532.6 KIK67152.1 - 1.1e-18 68.1 0.0 2.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRNT PF15174.6 KIK67153.1 - 0.09 12.8 0.2 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Prion-related protein testis-specific TMF_TATA_bd PF12325.8 KIK67153.1 - 0.098 12.9 7.5 3.7 7.8 1.7 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KIK67153.1 - 0.16 12.0 6.8 6 6.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DnaG_DnaB_bind PF08278.11 KIK67153.1 - 0.5 11.0 5.8 0.64 10.6 3.5 2.4 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding bZIP_Maf PF03131.17 KIK67153.1 - 3.7 8.1 7.1 1.9 9.1 2.8 2.7 2 1 0 2 2 2 0 bZIP Maf transcription factor Cluap1 PF10234.9 KIK67153.1 - 7.9 5.8 9.0 2.3 7.5 2.8 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 Melibiase_2 PF16499.5 KIK67154.1 - 1.3e-52 178.8 2.6 3.1e-52 177.5 2.6 1.6 1 1 0 1 1 1 1 Alpha galactosidase A CBM_1 PF00734.18 KIK67154.1 - 1.2e-11 44.3 10.6 3.9e-11 42.7 10.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Melibiase_C PF17801.1 KIK67154.1 - 2.3e-10 40.4 0.0 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIK67154.1 - 0.00013 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase VanZ PF04892.12 KIK67155.1 - 3e-05 24.7 5.3 6.8e-05 23.5 5.2 1.6 1 1 0 1 1 1 1 VanZ like family DUF4199 PF13858.6 KIK67155.1 - 0.021 15.2 1.4 0.027 14.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) 7TMR-DISM_7TM PF07695.11 KIK67155.1 - 0.81 9.5 11.1 0.9 9.4 9.4 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling ThrE PF06738.12 KIK67157.1 - 1.4e-52 178.5 18.9 4.4e-50 170.3 5.9 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIK67157.1 - 3.8e-12 46.5 6.5 3.8e-12 46.5 6.5 2.8 2 1 1 3 3 3 1 Threonine/Serine exporter, ThrE RNA_pol_Rpb1_3 PF04983.18 KIK67158.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 HicA_toxin PF07927.12 KIK67159.1 - 4.7e-08 32.9 0.0 1.4e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, CE2_N PF17996.1 KIK67160.1 - 9.5e-08 32.0 0.4 0.0012 18.8 0.1 2.5 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal CD34_antigen PF06365.12 KIK67160.1 - 0.0071 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF2207 PF09972.9 KIK67160.1 - 0.018 13.8 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_LMP1 PF05297.11 KIK67161.1 - 2.2 7.4 4.1 3.6 6.7 4.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATP_transf PF09830.9 KIK67162.1 - 3.1e-19 68.9 0.1 6.2e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 KIK67162.1 - 0.029 14.1 0.1 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) HIT PF01230.23 KIK67162.1 - 0.13 13.0 0.2 0.4 11.5 0.0 1.8 2 0 0 2 2 2 0 HIT domain Bromodomain PF00439.25 KIK67163.1 - 6.9e-22 77.3 0.0 1.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PAZ PF02170.22 KIK67164.1 - 0.0072 16.1 0.0 0.0097 15.7 0.0 1.1 1 0 0 1 1 1 1 PAZ domain EphA2_TM PF14575.6 KIK67164.1 - 0.11 13.4 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KIK67164.1 - 0.22 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ILVD_EDD PF00920.21 KIK67165.1 - 3e-201 669.5 0.0 3.4e-201 669.4 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family ATG22 PF11700.8 KIK67166.1 - 8.5e-110 367.6 21.3 9.8e-110 367.4 21.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIK67166.1 - 2.3e-10 39.9 39.4 2.4e-08 33.3 12.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2721 PF11026.8 KIK67166.1 - 2.3 8.1 6.3 0.36 10.7 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) TPR_1 PF00515.28 KIK67167.1 - 7.1e-18 63.6 0.8 2.1e-05 24.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67167.1 - 1.8e-15 55.7 5.4 0.00012 21.9 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK67167.1 - 1.1e-10 40.9 0.5 0.0091 16.1 0.0 4.7 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK67167.1 - 8.9e-10 39.1 6.2 1.7e-07 31.8 0.3 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK67167.1 - 2.2e-08 34.2 10.5 0.012 16.4 0.0 6.2 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK67167.1 - 1.2e-07 31.9 7.7 0.0017 18.6 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK67167.1 - 1.7e-06 27.6 0.7 1.8 8.8 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK67167.1 - 4.5e-06 26.7 0.4 0.77 10.3 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK67167.1 - 2.1e-05 24.1 6.9 0.00066 19.3 0.1 3.4 2 1 2 4 4 4 2 TPR repeat TPR_6 PF13174.6 KIK67167.1 - 7.9e-05 23.0 0.6 0.52 11.0 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK67167.1 - 0.00013 22.4 11.3 0.039 14.5 0.3 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK67167.1 - 0.00054 19.7 6.4 2.2 8.3 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIK67167.1 - 0.0062 15.8 3.7 0.15 11.2 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK67167.1 - 0.045 13.9 5.5 1.9 8.7 0.3 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KIK67167.1 - 0.049 13.0 0.1 0.19 11.1 0.0 2.0 2 1 0 2 2 2 0 Coatomer epsilon subunit DUF4810 PF16068.5 KIK67167.1 - 0.051 14.1 0.0 0.19 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 KIK67167.1 - 0.052 13.9 1.1 0.88 10.0 0.4 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat ETF PF01012.21 KIK67168.1 - 3e-34 118.5 0.1 4.9e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KIK67168.1 - 1.3e-31 108.4 0.3 3e-31 107.3 0.3 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain BMC PF00936.19 KIK67168.1 - 0.029 14.3 1.9 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 BMC domain FAD_binding_3 PF01494.19 KIK67169.1 - 1.9e-16 60.3 0.0 4.3e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain PAC2 PF09754.9 KIK67171.1 - 5.4e-21 75.6 0.0 7.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 PAC2 family NUC173 PF08161.12 KIK67172.1 - 1.7e-53 181.3 0.0 1.2e-51 175.3 0.0 3.0 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 KIK67172.1 - 0.0096 16.1 0.2 0.34 11.3 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat MMS19_C PF12460.8 KIK67172.1 - 0.033 13.3 0.2 0.033 13.3 0.2 3.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Acyltransferase PF01553.21 KIK67173.1 - 1.1e-14 54.3 0.0 1.1e-11 44.4 0.0 3.0 3 0 0 3 3 3 2 Acyltransferase ABC2_membrane PF01061.24 KIK67173.1 - 0.13 11.6 12.0 0.38 10.1 10.0 2.0 2 0 0 2 2 2 0 ABC-2 type transporter ABC_tran PF00005.27 KIK67175.1 - 9.3e-47 159.0 0.0 7.9e-27 94.4 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK67175.1 - 1.7e-13 51.1 0.0 0.00021 21.2 0.0 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK67175.1 - 4e-11 42.8 0.0 0.0016 17.9 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KIK67175.1 - 3.4e-10 39.7 0.0 6.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KIK67175.1 - 5.9e-06 26.9 0.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIK67175.1 - 7.6e-06 26.0 0.1 0.018 15.1 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK67175.1 - 1.1e-05 25.0 2.2 0.14 11.9 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK67175.1 - 2.3e-05 24.8 0.6 1.8 9.0 0.0 4.0 4 0 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 KIK67175.1 - 2.8e-05 24.7 0.0 0.13 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIK67175.1 - 8.3e-05 22.9 0.1 1.1 9.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KIK67175.1 - 0.0002 21.6 0.0 0.64 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIK67175.1 - 0.00022 21.2 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KIK67175.1 - 0.00035 20.8 0.0 0.27 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 KIK67175.1 - 0.00036 20.5 1.8 8.9 6.9 0.1 4.5 3 0 0 3 3 3 0 HEAT repeat Tudor-knot PF11717.8 KIK67175.1 - 0.00045 20.0 0.1 0.00099 18.9 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain NACHT PF05729.12 KIK67175.1 - 0.0006 19.8 0.0 0.043 13.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain DUF87 PF01935.17 KIK67175.1 - 0.00063 19.9 0.2 2.1 8.4 0.0 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 KIK67175.1 - 0.0012 18.9 0.1 0.056 13.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 KIK67175.1 - 0.0015 17.6 0.4 0.97 8.4 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KIK67175.1 - 0.0039 16.9 0.0 3.3 7.4 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK67175.1 - 0.0056 16.4 0.3 4.3 7.0 0.1 3.5 4 0 0 4 4 3 1 AAA domain ATP_bind_1 PF03029.17 KIK67175.1 - 0.0098 15.7 0.5 5.4 6.7 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KIK67175.1 - 0.014 14.9 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Adaptin_N PF01602.20 KIK67175.1 - 0.015 13.9 0.2 0.035 12.7 0.2 1.5 2 0 0 2 2 2 0 Adaptin N terminal region IFRD PF05004.13 KIK67175.1 - 0.016 14.3 0.1 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Roc PF08477.13 KIK67175.1 - 0.02 15.1 0.0 9.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK67175.1 - 0.025 14.0 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family CLASP_N PF12348.8 KIK67175.1 - 0.047 13.3 0.0 7.3 6.1 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal MMS19_C PF12460.8 KIK67175.1 - 0.061 12.4 0.8 0.21 10.7 0.3 2.0 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 KIK67175.1 - 0.063 13.7 5.1 2 8.8 0.1 4.3 3 2 2 5 5 4 0 HEAT repeats AAA_15 PF13175.6 KIK67175.1 - 0.073 12.8 1.1 5.8 6.5 0.2 2.4 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KIK67175.1 - 0.082 13.3 0.2 9.9 6.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.20 KIK67175.1 - 0.1 11.7 0.0 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 KIK67175.1 - 0.11 12.5 0.1 19 5.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KIK67175.1 - 0.11 11.7 0.0 11 5.1 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain AAA_27 PF13514.6 KIK67175.1 - 0.11 12.0 0.0 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KIK67175.1 - 0.16 10.6 0.0 3.8 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain HEAT_EZ PF13513.6 KIK67175.1 - 0.24 11.9 8.0 1.6 9.4 0.4 4.2 2 1 2 4 4 3 0 HEAT-like repeat Homeodomain PF00046.29 KIK67176.1 - 1e-15 57.3 3.6 1.6e-15 56.7 3.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK67176.1 - 0.00066 19.5 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KIK67176.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pkinase PF00069.25 KIK67177.1 - 6.7e-59 199.4 0.1 8.2e-38 130.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67177.1 - 5.7e-25 88.1 0.1 4.9e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK67177.1 - 3.4e-05 23.3 0.2 0.0023 17.3 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KIK67177.1 - 0.0025 17.8 0.8 0.0065 16.4 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK67177.1 - 0.0068 15.4 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK67177.1 - 0.075 11.8 0.8 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_C PF00433.24 KIK67177.1 - 0.095 13.4 0.0 0.36 11.6 0.0 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 KIK67177.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KIK67177.1 - 0.17 10.8 0.2 0.26 10.2 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C2H2 PF00096.26 KIK67178.1 - 3.8e-16 58.5 3.3 8.5e-08 32.2 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK67178.1 - 2.6e-11 43.3 3.4 1.5e-05 25.4 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK67178.1 - 1.7e-09 37.6 11.7 6.1e-06 26.4 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 KIK67178.1 - 6e-06 26.0 1.1 0.0039 17.1 0.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KIK67178.1 - 2.2e-05 24.6 1.3 4.4e-05 23.7 0.6 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK67178.1 - 3.4e-05 23.7 3.1 0.0021 18.0 0.7 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIK67178.1 - 0.00022 21.5 2.4 0.00031 21.0 0.5 2.1 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KIK67178.1 - 0.00075 19.8 0.4 0.00086 19.6 0.4 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KIK67178.1 - 0.0015 18.6 0.5 0.31 11.2 0.2 2.1 1 1 1 2 2 2 2 Zinc ribbon domain DUF3268 PF11672.8 KIK67178.1 - 0.0039 17.5 0.2 0.0041 17.4 0.2 1.1 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2HE PF16278.5 KIK67178.1 - 0.0064 16.9 0.7 0.015 15.7 0.1 1.8 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 KIK67178.1 - 0.011 15.9 0.1 0.024 14.8 0.0 1.5 1 1 1 2 2 2 0 Aberrant zinc-finger Zn_ribbon_SprT PF17283.2 KIK67178.1 - 0.014 15.3 2.1 0.38 10.7 0.3 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-BED PF02892.15 KIK67178.1 - 0.016 15.2 3.1 0.17 12.0 3.1 2.1 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_11 PF16622.5 KIK67178.1 - 0.088 12.6 3.3 4 7.3 0.4 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF674 PF05056.12 KIK67178.1 - 0.091 11.6 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF674) zf-C2H2_2 PF12756.7 KIK67178.1 - 0.12 12.8 0.2 0.8 10.1 0.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RRN7 PF11781.8 KIK67178.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_C2HC_14 PF18574.1 KIK67178.1 - 0.24 11.2 2.7 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain zf-H2C2_5 PF13909.6 KIK67178.1 - 2.7 7.8 14.4 0.86 9.4 1.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain BolA PF01722.18 KIK67179.1 - 3.1e-29 101.1 0.4 3.7e-29 100.8 0.4 1.1 1 0 0 1 1 1 1 BolA-like protein TPR_19 PF14559.6 KIK67181.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 KIK67182.1 - 9.1e-37 126.7 1.6 3.9e-35 121.3 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK67182.1 - 9.9e-37 126.9 0.1 2.5e-35 122.3 0.0 2.8 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIK67182.1 - 9.1e-16 58.3 0.0 3.2e-15 56.5 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-C2H2 PF00096.26 KIK67183.1 - 9.4e-10 38.4 11.3 8.9e-05 22.7 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK67183.1 - 8.9e-08 32.2 6.6 4.7e-06 26.8 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK67183.1 - 5.9e-05 23.6 5.8 0.0023 18.6 1.8 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KIK67183.1 - 0.00099 19.4 0.7 0.66 10.4 0.6 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK67183.1 - 0.0012 18.8 3.5 0.033 14.2 1.0 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK67183.1 - 0.056 13.7 0.3 0.056 13.7 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Acetyltransf_1 PF00583.25 KIK67184.1 - 3e-16 59.7 0.0 3.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK67184.1 - 8.1e-09 35.8 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK67184.1 - 1.7e-08 34.4 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK67184.1 - 5e-05 23.2 0.0 7.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KIK67184.1 - 0.00079 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KIK67184.1 - 0.00095 19.3 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK67184.1 - 0.0085 16.8 0.0 0.01 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK67184.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KIK67186.1 - 1.1e-58 198.7 0.0 1.4e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67186.1 - 3.3e-34 118.4 0.0 4.2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK67186.1 - 0.0001 21.7 0.0 0.00029 20.3 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIK67186.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Zn_clus PF00172.18 KIK67187.1 - 5.8e-08 32.7 8.6 9.1e-08 32.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin PF08613.11 KIK67189.1 - 0.0007 20.0 0.0 0.0029 18.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIK67189.1 - 0.0099 15.6 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain SLT PF01464.20 KIK67191.1 - 1e-11 44.5 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain TPR_1 PF00515.28 KIK67192.1 - 5.2e-10 38.7 0.7 4.9e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67192.1 - 3.2e-07 29.9 0.4 0.00042 20.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK67192.1 - 1.8e-06 27.5 0.7 0.0014 18.2 0.1 2.7 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KIK67192.1 - 6.6e-06 25.9 0.8 0.0022 18.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK67192.1 - 8.6e-05 22.7 0.2 0.00093 19.4 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat PPP5 PF08321.12 KIK67192.1 - 0.00016 21.9 0.2 0.00047 20.4 0.0 1.8 2 1 0 2 2 2 1 PPP5 TPR repeat region TPR_15 PF13429.6 KIK67192.1 - 0.0018 17.5 0.1 0.0023 17.2 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK67192.1 - 0.0025 18.3 0.3 0.073 13.6 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK67192.1 - 0.0032 18.1 0.0 0.0047 17.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK67192.1 - 0.032 14.8 0.5 0.073 13.7 0.1 1.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK67192.1 - 0.043 14.0 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Metallophos PF00149.28 KIK67193.1 - 1.7e-25 90.7 0.1 2.6e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KIK67193.1 - 7.7e-14 51.8 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region Mito_carr PF00153.27 KIK67194.1 - 2.9e-65 216.2 3.2 1.7e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KIK67195.1 - 2.2e-11 43.4 0.0 2e-05 24.3 0.0 2.7 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KIK67195.1 - 5.2e-07 29.6 0.2 1.3e-06 28.3 0.2 1.7 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KIK67195.1 - 0.015 16.1 0.0 0.035 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 KIK67195.1 - 0.12 12.6 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Kin17_mid PF10357.9 KIK67196.1 - 4.6e-50 168.8 0.6 9.1e-50 167.8 0.6 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KIK67196.1 - 0.0012 19.1 4.8 0.003 17.9 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK67196.1 - 0.014 15.7 3.6 0.037 14.3 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIK67196.1 - 0.043 14.2 4.1 0.069 13.5 1.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ATP-sulfurylase PF01747.17 KIK67197.1 - 8.2e-87 290.1 0.1 1.1e-86 289.7 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KIK67197.1 - 1.5e-53 180.7 0.0 2.3e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KIK67197.1 - 1.2e-47 161.7 0.0 1.8e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KIK67197.1 - 0.0038 17.8 0.0 0.0091 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIK67197.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 RsmJ PF04378.13 KIK67197.1 - 0.12 11.6 0.0 0.35 10.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ ERO1 PF04137.15 KIK67199.1 - 9.9e-127 423.0 0.0 1.2e-126 422.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) p450 PF00067.22 KIK67201.1 - 1.3e-71 241.8 0.1 1.8e-71 241.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 KH_1 PF00013.29 KIK67202.1 - 1.2e-91 300.5 28.6 3.8e-13 49.1 0.4 14.3 15 1 0 15 15 15 11 KH domain KH_2 PF07650.17 KIK67202.1 - 6.6e-13 48.3 18.5 0.011 15.6 0.1 8.7 7 2 2 9 9 9 5 KH domain SLS PF14611.6 KIK67202.1 - 3.3e-07 30.3 29.5 0.03 14.2 0.2 8.6 7 3 3 10 10 10 5 Mitochondrial inner-membrane-bound regulator MOEP19 PF16005.5 KIK67202.1 - 0.00012 22.0 0.0 0.077 13.0 0.0 3.3 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 KIK67202.1 - 0.001 19.1 11.3 0.92 9.6 0.1 5.5 5 0 0 5 5 5 2 NusA-like KH domain KH_4 PF13083.6 KIK67202.1 - 0.003 17.4 11.6 17 5.4 0.0 7.5 7 1 0 8 8 8 1 KH domain DUF4974 PF16344.5 KIK67202.1 - 0.0032 17.4 0.1 0.89 9.6 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4974) SelB-wing_3 PF09107.11 KIK67202.1 - 0.019 14.6 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Fungal_trans PF04082.18 KIK67203.1 - 5.6e-14 51.8 0.6 1.6e-12 47.0 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIK67204.1 - 0.002 17.2 0.0 0.0049 15.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIK67205.1 - 3e-27 95.3 0.2 3e-27 95.3 0.2 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain MmgE_PrpD PF03972.14 KIK67206.1 - 4.1e-158 526.5 0.0 4.7e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PAM2 PF07145.15 KIK67207.1 - 0.037 13.7 0.3 0.13 12.0 0.3 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RNase_H2-Ydr279 PF09468.10 KIK67208.1 - 2.7e-16 60.2 0.2 5.8e-16 59.1 0.0 1.6 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KIK67208.1 - 5.7e-14 52.1 0.1 1.2e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain zf-SNAP50_C PF12251.8 KIK67209.1 - 3.7e-29 101.8 0.0 4.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal COG7 PF10191.9 KIK67210.1 - 1.4e-78 265.0 0.9 9e-48 163.1 0.1 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) RINT1_TIP1 PF04437.13 KIK67210.1 - 0.0025 16.8 2.0 0.068 12.1 0.0 3.3 4 0 0 4 4 4 1 RINT-1 / TIP-1 family AOX PF01786.17 KIK67210.1 - 0.0056 16.3 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Alternative oxidase Baculo_PEP_C PF04513.12 KIK67210.1 - 0.7 9.9 3.9 1.3 9.1 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAG PF08514.11 KIK67211.1 - 3e-29 101.2 1.4 5.6e-29 100.4 0.1 2.3 2 0 0 2 2 2 1 STAG domain GBP PF02263.19 KIK67211.1 - 0.012 14.9 1.4 0.067 12.4 0.1 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain HEAT PF02985.22 KIK67211.1 - 0.084 13.2 1.8 14 6.2 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat SAMP PF05924.11 KIK67211.1 - 1.5 8.2 4.7 1.1 8.6 0.3 3.2 2 0 0 2 2 2 0 SAMP Motif Slu7 PF11708.8 KIK67212.1 - 3.8e-107 358.1 16.2 3.8e-107 358.1 16.2 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KIK67212.1 - 0.018 14.7 0.3 0.036 13.8 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle EHN PF06441.12 KIK67213.1 - 1.8e-29 102.3 0.0 3.6e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK67213.1 - 9.6e-12 45.1 0.3 4.3e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 KIK67213.1 - 0.0021 16.8 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.7 KIK67213.1 - 0.0064 17.1 0.3 0.011 16.4 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.19 KIK67215.1 - 2.2e-37 128.1 0.0 3.6e-36 124.2 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK67215.1 - 2.1e-23 82.4 0.0 3e-23 82.0 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK67215.1 - 0.0027 17.9 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK67215.1 - 0.027 15.0 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DNA_pol3_alpha PF07733.12 KIK67215.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain DUF1771 PF08590.10 KIK67216.1 - 0.0098 16.3 7.4 0.0098 16.3 7.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Ctr PF04145.15 KIK67216.1 - 2.3 8.8 7.8 31 5.2 7.8 2.3 1 1 0 1 1 1 0 Ctr copper transporter family SNF2_N PF00176.23 KIK67217.1 - 3.9e-61 206.7 0.1 6.7e-61 205.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KIK67217.1 - 7.4e-25 87.2 0.5 3.5e-24 85.1 0.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KIK67217.1 - 1.5e-19 69.7 5.2 2.7e-14 52.8 0.4 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KIK67217.1 - 2.5e-18 66.4 0.0 8.1e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK67217.1 - 1.6e-07 31.5 0.0 5.7e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KIK67217.1 - 1.9e-07 31.5 0.4 1.9e-07 31.5 0.4 4.2 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KIK67217.1 - 0.00018 22.1 0.4 0.0014 19.2 0.4 2.6 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 Methyltransf_18 PF12847.7 KIK67217.1 - 0.023 14.6 0.7 0.2 11.6 0.7 2.3 2 0 0 2 2 2 0 Methyltransferase domain FlhC PF05280.11 KIK67217.1 - 0.14 11.8 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) CHDCT2 PF08074.11 KIK67217.1 - 0.64 10.2 0.0 0.64 10.2 0.0 3.5 4 1 0 4 4 4 0 CHDCT2 (NUC038) domain Tfb4 PF03850.14 KIK67218.1 - 1.5e-82 277.2 0.0 1.9e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.18 KIK67219.1 - 3.6e-49 167.4 0.9 5.2e-49 166.9 0.9 1.2 1 0 0 1 1 1 1 Asparaginase Abhydrolase_3 PF07859.13 KIK67220.1 - 4.3e-30 105.2 0.0 2e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGA_cap PF09587.10 KIK67220.1 - 0.0097 15.4 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap zf-C2H2 PF00096.26 KIK67221.1 - 1e-12 47.8 12.6 0.00044 20.6 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK67221.1 - 6.6e-08 32.8 14.8 0.01 16.6 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK67221.1 - 2.1e-07 30.8 3.6 0.00024 21.0 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK67221.1 - 1.1e-05 25.6 14.8 7e-05 23.1 0.1 4.9 4 1 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KIK67221.1 - 0.00028 21.2 4.8 0.17 12.3 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIK67221.1 - 0.017 15.4 1.0 1.1 9.6 0.5 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KIK67221.1 - 0.054 14.1 14.5 0.91 10.2 3.9 3.6 2 1 2 4 4 4 0 FOXP coiled-coil domain OSTMP1 PF09777.9 KIK67221.1 - 0.074 12.4 0.6 0.1 12.0 0.6 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_aberr PF17017.5 KIK67221.1 - 0.12 12.5 1.7 9.6 6.3 0.0 2.9 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KIK67221.1 - 0.13 12.6 3.1 0.3 11.4 2.3 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KIK67221.1 - 0.13 12.6 4.8 1.5 9.2 2.5 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KIK67221.1 - 0.17 12.2 6.8 0.75 10.2 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KIK67221.1 - 0.29 11.9 6.2 0.19 12.5 1.3 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 KIK67221.1 - 0.56 10.0 4.4 1.1 9.1 0.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KIK67221.1 - 0.78 9.7 4.8 0.45 10.5 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TPR_1 PF00515.28 KIK67222.1 - 2e-14 52.7 12.7 0.0019 17.9 0.2 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67222.1 - 2.5e-12 45.9 17.0 0.00027 20.8 0.9 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK67222.1 - 9.9e-10 37.9 6.4 0.072 13.3 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK67222.1 - 3.6e-09 37.0 13.7 5.6e-06 26.8 1.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK67222.1 - 5.8e-09 35.5 10.0 0.00038 20.1 1.1 4.3 2 2 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KIK67222.1 - 7.3e-08 32.9 20.4 4.1e-06 27.3 1.7 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK67222.1 - 4.3e-06 27.1 16.7 0.0034 18.1 0.4 5.9 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK67222.1 - 8.5e-06 25.8 10.6 3.7 8.1 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK67222.1 - 2.1e-05 24.6 7.3 0.00043 20.4 1.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK67222.1 - 0.00011 22.4 5.6 0.0022 18.2 2.2 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KIK67222.1 - 0.0008 19.6 17.2 0.019 15.3 2.9 4.1 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK67222.1 - 0.012 15.6 7.2 1.7 8.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK67222.1 - 0.012 15.9 12.1 1.3 9.4 0.9 4.9 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK67222.1 - 3.3 8.5 6.8 1.1e+02 3.8 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KIK67222.1 - 5.8 7.1 6.3 9.3 6.4 0.1 3.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ANAPC_CDC26 PF10471.9 KIK67223.1 - 0.0012 19.6 2.7 0.3 11.9 0.4 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex APC subunit CDC26 PRA1 PF03208.19 KIK67224.1 - 6.9e-38 129.5 0.8 8.4e-38 129.2 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein PSI_PsaJ PF01701.18 KIK67224.1 - 0.5 10.9 10.2 1.8 9.2 0.8 3.1 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Zn_clus PF00172.18 KIK67225.1 - 0.0004 20.4 11.4 0.00071 19.6 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KIK67225.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold Methyltransf_31 PF13847.6 KIK67226.1 - 4.5e-08 33.0 0.0 5.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK67226.1 - 6.9e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmC_N PF17827.1 KIK67226.1 - 2.3e-06 28.1 0.0 1.4e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 KIK67226.1 - 9.3e-05 22.3 0.0 0.00024 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK67226.1 - 0.00013 22.6 0.0 0.00021 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 KIK67226.1 - 0.00032 20.0 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.13 KIK67226.1 - 0.0046 16.4 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 KIK67226.1 - 0.0085 15.5 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 RNA methyltransferase UPF0020 PF01170.18 KIK67226.1 - 0.023 14.4 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 KIK67226.1 - 0.14 13.0 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK67226.1 - 0.19 12.4 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Allantoicase PF03561.15 KIK67227.1 - 6.1e-93 308.4 0.0 5.3e-46 156.2 0.1 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 KIK67227.1 - 2.1e-49 167.8 0.0 2.9e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF4644 PF15486.6 KIK67227.1 - 0.12 12.1 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) BRE1 PF08647.11 KIK67228.1 - 4.8e-18 65.0 10.5 4.8e-18 65.0 10.5 7.1 7 2 3 10 10 10 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KIK67228.1 - 2.4e-07 30.5 6.7 5.3e-07 29.4 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK67228.1 - 2.3e-06 27.4 10.4 4.5e-06 26.4 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK67228.1 - 3.4e-06 26.9 9.9 7.3e-06 25.9 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK67228.1 - 5e-06 26.3 9.2 9.9e-06 25.3 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK67228.1 - 6.9e-05 23.1 8.2 0.00015 22.1 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK67228.1 - 9.3e-05 22.2 6.5 0.00021 21.1 6.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK67228.1 - 0.0001 22.3 6.3 0.00023 21.1 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIK67228.1 - 0.0049 17.1 4.4 0.012 15.9 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIK67228.1 - 0.011 15.6 3.8 0.024 14.5 3.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KIK67228.1 - 0.041 14.0 4.9 0.11 12.6 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 KIK67228.1 - 0.27 11.2 3.9 0.6 10.0 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KIK67228.1 - 0.48 10.3 6.4 1.8 8.4 6.0 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIK67228.1 - 0.5 10.6 7.2 1 9.6 7.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 KIK67228.1 - 1.4 9.0 6.1 3.7 7.7 6.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KIK67228.1 - 1.6 8.3 4.5 0.51 9.8 1.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KIK67228.1 - 2.1 8.5 6.7 2.4 8.2 4.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Ribosomal_S9 PF00380.19 KIK67229.1 - 1e-45 155.1 0.2 2.9e-45 153.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 CASP_C PF08172.12 KIK67230.1 - 8.6e-76 254.6 2.7 8.6e-76 254.6 2.7 3.8 2 1 2 4 4 4 2 CASP C terminal CtIP_N PF10482.9 KIK67230.1 - 0.0045 17.0 2.2 0.0045 17.0 2.2 5.2 4 1 2 6 6 6 1 Tumour-suppressor protein CtIP N-terminal domain KLRAQ PF10205.9 KIK67230.1 - 0.011 16.0 0.4 0.011 16.0 0.4 6.3 4 1 3 7 7 7 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 KIK67230.1 - 0.82 10.1 40.5 3 8.3 0.5 8.4 4 1 4 10 10 10 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KIK67230.1 - 6.8 6.9 74.2 0.44 10.7 1.0 5.9 3 1 3 6 6 6 0 Autophagy protein 16 (ATG16) BSD PF03909.17 KIK67231.1 - 9.7e-19 67.1 0.1 5.7e-13 48.7 0.1 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KIK67231.1 - 2.1e-17 63.2 0.0 4.2e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2458 PF10454.9 KIK67231.1 - 0.03 14.0 0.9 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Pkinase PF00069.25 KIK67232.1 - 1.8e-52 178.3 0.0 2.9e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67232.1 - 3.4e-35 121.6 0.0 4.6e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK67232.1 - 2.4e-06 27.1 0.0 4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK67232.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIK67232.1 - 0.12 12.2 0.0 0.84 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family BAG PF02179.16 KIK67233.1 - 4.8e-18 65.4 0.1 6.5e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KIK67233.1 - 5.3e-07 29.3 0.0 9.9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIK67233.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Bromodomain PF00439.25 KIK67234.1 - 4e-26 90.9 0.8 7e-26 90.1 0.8 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KIK67234.1 - 1.8e-05 24.9 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK67234.1 - 2.7e-05 24.1 0.0 5.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK67234.1 - 0.0009 19.6 0.2 0.0016 18.8 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain malic PF00390.19 KIK67234.1 - 0.016 15.0 0.1 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain UPF0004 PF00919.20 KIK67234.1 - 0.13 12.3 0.2 0.36 10.9 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DPBB_1 PF03330.18 KIK67236.1 - 3.8e-05 23.9 0.0 8.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Pro_isomerase PF00160.21 KIK67237.1 - 3.7e-42 144.3 0.1 4.5e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4134 PF13572.6 KIK67237.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) DEAD PF00270.29 KIK67238.1 - 1.4e-38 132.4 0.0 2.7e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK67238.1 - 2.4e-18 66.5 0.0 2e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIK67238.1 - 4.1e-18 65.4 0.5 9.1e-18 64.2 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIK67238.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MOZ_SAS PF01853.18 KIK67239.1 - 4.2e-79 264.4 0.2 6.1e-79 263.8 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIK67239.1 - 3.2e-21 74.7 2.5 7e-21 73.6 2.5 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KIK67239.1 - 1.7e-17 63.1 0.1 3.7e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KIK67239.1 - 0.0013 19.1 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK67239.1 - 0.0089 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_Mga PF08280.11 KIK67239.1 - 0.033 14.2 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain LAG1-DNAbind PF09271.11 KIK67240.1 - 2.7e-50 170.9 0.0 4.1e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KIK67240.1 - 1.7e-19 70.5 0.0 5.6e-18 65.6 0.0 2.6 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Shugoshin_N PF07558.11 KIK67242.1 - 5.7e-05 22.9 5.6 0.00013 21.7 5.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 KIK67242.1 - 0.0029 17.7 5.9 0.0041 17.2 3.4 2.4 1 1 1 2 2 2 2 bZIP transcription factor Fungal_TACC PF12709.7 KIK67242.1 - 0.0047 17.4 3.2 0.01 16.3 3.2 1.6 1 0 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins ATG16 PF08614.11 KIK67242.1 - 0.0099 16.1 4.3 0.0099 16.1 4.3 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) YabA PF06156.13 KIK67242.1 - 0.012 16.2 3.1 0.012 16.2 3.1 2.5 3 0 0 3 3 3 0 Initiation control protein YabA GIT_CC PF16559.5 KIK67242.1 - 0.024 14.5 3.0 0.08 12.8 3.0 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 KIK67242.1 - 0.07 13.2 6.3 0.16 12.0 6.3 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 KIK67242.1 - 0.86 9.4 7.0 6.1 6.7 7.0 2.2 1 1 0 1 1 1 0 Septum formation initiator Titin_Ig-rpts PF06582.12 KIK67242.1 - 0.97 9.4 5.5 0.14 12.2 1.1 1.9 2 0 0 2 2 2 0 Titin repeat bZIP_2 PF07716.15 KIK67242.1 - 2.1 8.5 11.1 0.64 10.1 4.4 3.1 2 1 1 3 3 3 0 Basic region leucine zipper zf-GRF PF06839.12 KIK67243.1 - 1.7e-05 24.8 4.4 1.9e-05 24.7 4.4 1.1 1 0 0 1 1 1 1 GRF zinc finger PAC4 PF16093.5 KIK67244.1 - 7.6e-13 48.5 0.1 1e-12 48.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Put_Phosphatase PF06888.12 KIK67245.1 - 8.4e-55 185.7 0.0 9.4e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KIK67245.1 - 1.3e-07 32.2 0.1 3.2e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK67245.1 - 0.0019 18.5 0.0 0.025 14.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK67245.1 - 0.035 14.2 1.3 6.9 6.7 1.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KIK67245.1 - 0.17 11.3 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) 5_nucleotid PF05761.14 KIK67245.1 - 0.24 10.3 0.0 0.39 9.6 0.0 1.5 1 1 0 1 1 1 0 5' nucleotidase family Pkinase PF00069.25 KIK67246.1 - 8.1e-52 176.2 0.1 1.9e-51 174.9 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67246.1 - 3.4e-22 79.0 0.0 5.6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK67246.1 - 1.9e-05 24.7 0.1 3.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK67246.1 - 0.00041 20.0 0.5 0.00088 18.9 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KIK67246.1 - 0.021 14.4 2.1 0.031 13.9 0.1 2.3 2 2 0 2 2 2 0 Choline/ethanolamine kinase BRCT PF00533.26 KIK67247.1 - 3.9e-32 110.5 0.1 1.4e-09 38.2 0.0 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIK67247.1 - 3.8e-27 94.0 0.2 5.2e-18 64.8 0.0 5.4 6 0 0 6 6 6 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 KIK67247.1 - 2.8e-24 84.9 0.1 3.4e-23 81.4 0.0 2.5 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KIK67247.1 - 3.2e-22 78.7 0.0 0.00015 22.1 0.0 5.7 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain DUF4510 PF14971.6 KIK67247.1 - 0.016 15.5 0.3 0.046 14.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) TRAM_LAG1_CLN8 PF03798.16 KIK67248.1 - 9.1e-31 107.1 22.5 9.1e-31 107.1 22.5 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIK67248.1 - 1.9e-15 56.2 1.6 1.9e-15 56.2 1.6 2.5 2 0 0 2 2 2 1 TRAM1-like protein 2-Hacid_dh_C PF02826.19 KIK67249.1 - 2.3e-46 157.4 0.0 3.7e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK67249.1 - 1.7e-18 66.6 0.0 2.4e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK67249.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3884 PF13024.6 KIK67249.1 - 0.0045 16.5 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3884) Shikimate_DH PF01488.20 KIK67249.1 - 0.0076 16.3 0.0 0.07 13.2 0.0 2.5 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK67249.1 - 0.065 13.7 0.3 1.2 9.7 0.4 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding EXS PF03124.14 KIK67250.1 - 8.1e-101 337.6 16.6 9.3e-101 337.4 16.6 1.0 1 0 0 1 1 1 1 EXS family zf-C2H2_jaz PF12171.8 KIK67251.1 - 3e-05 24.2 0.1 5.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK67251.1 - 0.00048 20.4 0.1 0.00087 19.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KIK67251.1 - 0.00057 19.9 0.5 0.0018 18.3 0.5 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KIK67251.1 - 0.0051 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.26 KIK67251.1 - 0.073 13.6 0.5 0.14 12.7 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK67251.1 - 0.11 13.4 0.2 0.24 12.4 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger TMCO5 PF14992.6 KIK67251.1 - 0.83 9.2 5.7 2 7.9 5.7 1.7 1 1 0 1 1 1 0 TMCO5 family Peptidase_S49_N PF08496.10 KIK67251.1 - 2.3 8.3 7.0 0.35 10.9 0.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal tRNA-synt_1 PF00133.22 KIK67252.1 - 4.5e-219 728.7 0.0 5.9e-219 728.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK67252.1 - 5.5e-26 91.4 0.1 1.2e-25 90.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIK67252.1 - 1.1e-12 47.5 0.3 0.00014 20.7 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIK67252.1 - 0.031 13.6 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TAL_FSA PF00923.19 KIK67253.1 - 1.3e-92 310.2 0.0 1.7e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase zinc_ribbon_16 PF17034.5 KIK67254.1 - 1.1e-18 67.6 7.0 2.2e-18 66.6 7.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family zf-ribbon_3 PF13248.6 KIK67254.1 - 0.28 10.7 2.7 13 5.3 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 KIK67254.1 - 4.5 7.0 10.6 0.87 9.3 5.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Homeodomain PF00046.29 KIK67255.1 - 5.8e-18 64.5 1.6 5.8e-18 64.5 1.6 1.7 2 0 0 2 2 2 1 Homeodomain Pkinase PF00069.25 KIK67257.1 - 1.7e-45 155.4 0.0 2.3e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67257.1 - 2e-29 102.7 0.0 2.9e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK67257.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ALAD PF00490.21 KIK67258.1 - 9.9e-123 409.3 0.0 1.2e-122 409.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Scs3p PF10261.9 KIK67259.1 - 7.2e-42 143.6 9.4 6.5e-33 114.3 2.2 2.3 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM CPT PF07931.12 KIK67259.1 - 0.026 14.4 0.1 0.05 13.5 0.0 1.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein EII-Sor PF03609.14 KIK67259.1 - 0.15 11.5 2.8 0.74 9.2 0.6 2.3 2 0 0 2 2 2 0 PTS system sorbose-specific iic component zf-4CXXC_R1 PF10497.9 KIK67260.1 - 3.9e-16 59.1 35.6 2.6e-08 34.0 13.4 2.4 2 0 0 2 2 2 2 Zinc-finger domain of monoamine-oxidase A repressor R1 Metallophos PF00149.28 KIK67261.1 - 6.5e-12 46.4 2.4 1.6e-11 45.1 1.6 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KIK67261.1 - 0.18 11.1 0.0 2.3 7.5 0.0 2.4 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily BSD PF03909.17 KIK67262.1 - 1.4e-10 41.0 0.2 3.1e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 BSD domain DUF883 PF05957.13 KIK67262.1 - 0.034 14.7 4.2 0.82 10.3 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4456 PF14644.6 KIK67262.1 - 0.062 13.0 2.9 2.6 7.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) MNHE PF01899.16 KIK67262.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF4666 PF15697.5 KIK67262.1 - 0.27 11.9 0.1 0.27 11.9 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4666) CPSase_sm_chain PF00988.22 KIK67263.1 - 8.1e-45 151.8 0.0 1.2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIK67263.1 - 1.8e-35 122.4 0.0 2.6e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK67263.1 - 2.8e-07 30.5 0.1 2.4e-05 24.2 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KIK67263.1 - 0.045 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family FAD_binding_3 PF01494.19 KIK67264.1 - 4e-19 69.1 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK67264.1 - 7.3e-06 25.4 0.0 0.0015 17.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK67264.1 - 7.8e-06 26.0 0.5 2e-05 24.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK67264.1 - 0.002 17.1 0.7 0.0065 15.4 0.1 2.0 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KIK67264.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK67264.1 - 0.03 13.0 0.0 1.7 7.2 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Coagulin PF02035.15 KIK67264.1 - 0.14 12.1 0.0 3.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Coagulin Pyr_redox PF00070.27 KIK67264.1 - 0.14 12.7 0.0 7.2 7.3 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK67264.1 - 0.2 10.9 0.1 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NADH_B2 PF14813.6 KIK67267.1 - 0.00011 22.0 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.11 KIK67267.1 - 0.023 15.2 0.0 0.023 15.2 0.0 1.0 1 0 0 1 1 1 0 SNARE associated Golgi protein Metallophos PF00149.28 KIK67268.1 - 5e-15 56.5 0.0 7.4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK67268.1 - 0.073 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UDPGP PF01704.18 KIK67270.1 - 1.2e-197 656.6 1.2 1.4e-197 656.4 1.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase WD40 PF00400.32 KIK67274.1 - 2.3e-26 91.5 14.3 3.6e-06 27.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK67274.1 - 2.6e-06 27.6 0.1 0.11 12.9 0.0 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK67274.1 - 6.6e-06 25.7 0.2 0.00011 21.7 0.1 2.4 2 1 0 2 2 2 1 WD40-like domain DUF5046 PF16465.5 KIK67274.1 - 0.00073 19.1 0.6 0.98 8.8 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) PQQ PF01011.21 KIK67274.1 - 0.033 14.1 0.3 8.3 6.5 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat LSM PF01423.22 KIK67275.1 - 9e-16 57.3 0.4 1.3e-15 56.8 0.4 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK67275.1 - 0.021 15.0 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S8e PF01201.22 KIK67276.1 - 5.9e-57 191.7 0.5 8.4e-57 191.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e FUSC_2 PF13515.6 KIK67280.1 - 1.6e-12 47.7 12.2 3.3e-12 46.6 12.2 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KIK67280.1 - 3.5e-08 33.6 0.2 6.4e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KIK67280.1 - 0.0014 17.7 0.7 0.002 17.3 0.0 1.5 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 KIK67280.1 - 0.077 11.8 6.8 0.16 10.8 6.8 1.7 1 1 0 1 1 1 0 Aluminium activated malate transporter Gelsolin PF00626.22 KIK67282.1 - 0.0027 17.6 0.0 12 5.9 0.0 3.2 3 0 0 3 3 3 2 Gelsolin repeat SAM_1 PF00536.30 KIK67284.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KIK67284.1 - 0.032 14.3 0.0 0.98 9.6 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) MscS_porin PF12795.7 KIK67284.1 - 0.059 12.9 2.1 0.099 12.2 2.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Med25 PF11232.8 KIK67286.1 - 0.044 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 CFC PF09443.10 KIK67286.1 - 0.096 12.6 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) CENP-Q PF13094.6 KIK67287.1 - 0.0099 16.1 6.8 0.023 14.9 6.8 1.7 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Macoilin PF09726.9 KIK67287.1 - 0.035 12.7 2.4 0.043 12.4 2.4 1.1 1 0 0 1 1 1 0 Macoilin family Pilus_CpaD PF09476.10 KIK67287.1 - 0.42 10.3 3.9 0.71 9.6 0.1 2.6 2 1 1 3 3 3 0 Pilus biogenesis CpaD protein (pilus_cpaD) Ribosomal_S7 PF00177.21 KIK67288.1 - 5.5e-35 120.2 2.1 6.7e-35 119.9 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TPK_catalytic PF04263.16 KIK67291.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Pho88 PF10032.9 KIK67292.1 - 4.4e-75 250.9 0.0 5e-75 250.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Nse4_C PF08743.10 KIK67293.1 - 2.3e-33 114.3 0.5 6.8e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KIK67293.1 - 4.5e-12 45.9 0.1 9.4e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Chloroplast_duf PF14476.6 KIK67293.1 - 0.052 12.5 0.2 0.099 11.6 0.2 1.3 1 0 0 1 1 1 0 Petal formation-expressed DUF948 PF06103.11 KIK67293.1 - 0.32 11.3 1.9 0.78 10.0 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliD_N PF02465.18 KIK67293.1 - 0.44 11.3 3.0 0.32 11.7 0.5 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SNF2_N PF00176.23 KIK67294.1 - 6.2e-62 209.3 0.0 1e-61 208.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIK67294.1 - 1.6e-17 63.2 0.0 4.1e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KIK67294.1 - 3.3e-14 53.5 0.1 9.4e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.31 KIK67294.1 - 5.1e-13 49.3 0.0 1e-06 29.1 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK67294.1 - 2.9e-11 43.7 0.0 7.7e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KIK67294.1 - 2.8e-07 30.3 11.8 6.5e-07 29.1 11.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK67294.1 - 2.8e-07 30.3 11.8 6.1e-07 29.2 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KIK67294.1 - 5e-07 29.7 0.0 1.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KIK67294.1 - 4.1e-06 27.0 10.7 9.5e-06 25.9 10.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK67294.1 - 4.2e-05 23.4 8.5 9.4e-05 22.3 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK67294.1 - 8.5e-05 22.5 14.9 0.0002 21.3 14.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK67294.1 - 0.00023 21.0 9.7 0.00047 20.0 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK67294.1 - 0.0021 18.3 7.6 0.0058 16.9 7.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KIK67294.1 - 0.028 14.6 12.3 0.061 13.5 12.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ARPC4 PF05856.12 KIK67295.1 - 1.2e-79 265.7 3.8 1.4e-79 265.6 3.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) GPS2_interact PF15784.5 KIK67295.1 - 0.22 12.0 1.6 1 9.9 0.1 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain FKBP_C PF00254.28 KIK67296.1 - 1.8e-30 105.1 0.0 4.2e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KIK67296.1 - 4.3e-19 69.0 0.0 4.3e-19 69.0 0.0 2.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain UPF0242 PF06785.11 KIK67296.1 - 0.29 11.2 3.3 0.42 10.7 3.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LAP1C PF05609.12 KIK67296.1 - 0.33 10.0 6.0 0.47 9.5 6.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) adh_short_C2 PF13561.6 KIK67297.1 - 9.1e-54 182.5 1.6 1.1e-53 182.2 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK67297.1 - 1.4e-41 142.2 0.3 1.7e-41 141.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK67297.1 - 5e-10 39.6 0.8 1.2e-09 38.3 0.8 1.5 1 1 0 1 1 1 1 KR domain SET PF00856.28 KIK67298.1 - 2e-10 41.3 2.5 2.6e-10 41.0 0.1 2.5 3 1 0 3 3 3 1 SET domain ubiquitin PF00240.23 KIK67299.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KIK67299.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK67299.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK67299.1 - 1.7e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK67299.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK67299.1 - 2.7e-17 62.9 12.0 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 KIK67299.1 - 5.6e-16 59.0 2.3 0.49 11.0 0.0 5.2 1 1 1 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIK67299.1 - 3.9e-12 46.3 0.7 1.8 8.4 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KIK67299.1 - 3.7e-09 36.2 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KIK67299.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 KIK67299.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 KIK67299.1 - 1.9e-07 31.3 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 KIK67299.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 KIK67299.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KIK67299.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 KIK67299.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIK67299.1 - 2.5e-05 23.8 0.2 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIK67299.1 - 6e-05 23.6 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 KIK67299.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIK67299.1 - 0.00069 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIK67299.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIK67299.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIK67299.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIK67299.1 - 0.47 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIK67299.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIK67299.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIK67299.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 KIK67299.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e Cation_efflux PF01545.21 KIK67300.1 - 5.7e-27 94.8 12.2 7.1e-27 94.4 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK67300.1 - 3e-05 24.1 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FAM72 PF14976.6 KIK67301.1 - 5.9e-16 58.9 7.8 3.8e-15 56.3 7.8 2.0 1 1 0 1 1 1 1 FAM72 protein RRP14 PF15459.6 KIK67301.1 - 0.12 13.0 0.2 0.2 12.3 0.2 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Yippee-Mis18 PF03226.14 KIK67301.1 - 2 8.7 9.3 0.64 10.3 5.1 2.2 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nop25 PF09805.9 KIK67302.1 - 4.5e-16 59.6 24.7 4.5e-16 59.6 24.7 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) V-SNARE_C PF12352.8 KIK67303.1 - 6.7e-14 51.9 1.6 6.7e-14 51.9 1.6 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIK67303.1 - 6.5e-06 26.0 0.8 3.3e-05 23.7 0.0 2.1 2 1 1 3 3 3 1 Sec20 zf-C4H2 PF10146.9 KIK67303.1 - 0.038 14.3 2.0 0.049 14.0 2.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Plasmid_RAQPRD PF09686.10 KIK67303.1 - 0.62 10.3 5.3 0.46 10.7 1.5 2.5 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Lactamase_B PF00753.27 KIK67304.1 - 6.2e-09 36.1 0.8 1.9e-07 31.3 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK67304.1 - 3.6e-05 23.4 0.4 8.6e-05 22.1 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain FAM60A PF15396.6 KIK67305.1 - 2.2 8.2 10.8 18 5.2 7.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A E1-E2_ATPase PF00122.20 KIK67306.1 - 8.8e-33 113.3 0.2 8.8e-33 113.3 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KIK67306.1 - 3.9e-23 81.9 0.6 7.3e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KIK67306.1 - 3.2e-20 73.3 0.6 1.1e-07 32.4 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIK67306.1 - 2.1e-06 27.6 2.0 2.1e-06 27.6 2.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KIK67306.1 - 4.5e-06 26.6 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIK67306.1 - 0.082 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Zn_clus PF00172.18 KIK67309.1 - 2.1e-09 37.3 8.0 3.6e-09 36.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Yae1_N PF09811.9 KIK67310.1 - 0.012 15.3 1.9 0.07 12.8 0.8 2.3 2 0 0 2 2 2 0 Essential protein Yae1, N terminal DUF724 PF05266.14 KIK67310.1 - 0.021 14.6 13.9 0.29 10.9 13.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Bcr-Abl_Oligo PF09036.10 KIK67310.1 - 0.043 13.8 4.9 0.041 13.9 2.7 2.1 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4663 PF15668.5 KIK67310.1 - 0.072 12.2 1.2 0.1 11.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) GrpE PF01025.19 KIK67310.1 - 4.6 6.9 19.7 0.059 13.0 6.2 2.6 1 1 1 2 2 2 0 GrpE FAM76 PF16046.5 KIK67310.1 - 5.5 6.2 13.0 8.1 5.7 13.0 1.3 1 0 0 1 1 1 0 FAM76 protein ALG11_N PF15924.5 KIK67311.1 - 7e-90 300.7 0.5 9.8e-90 300.2 0.5 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KIK67311.1 - 1.1e-25 90.2 0.0 1.9e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK67311.1 - 3.9e-12 46.8 0.0 7.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIK67311.1 - 0.00025 21.1 0.1 0.0008 19.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Peptidase_M24 PF00557.24 KIK67312.1 - 4e-58 196.5 0.0 5.3e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIK67312.1 - 5.4e-17 61.7 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RNase_PH PF01138.21 KIK67313.1 - 1.5e-19 70.8 0.0 4.2e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lipase_3 PF01764.25 KIK67315.1 - 7.5e-22 77.7 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK67315.1 - 0.00087 19.9 0.1 0.0011 19.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK67315.1 - 0.0062 16.3 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF3636 PF12331.8 KIK67318.1 - 0.011 15.6 0.1 0.093 12.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) HAUS-augmin3 PF14932.6 KIK67318.1 - 0.1 12.2 5.4 0.33 10.5 5.4 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.9 KIK67318.1 - 0.88 8.6 5.5 2.1 7.4 5.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sipho_Gp157 PF05565.11 KIK67318.1 - 1.2 9.1 14.3 0.32 11.0 10.8 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 MIF4G PF02854.19 KIK67319.1 - 7.5e-47 159.7 0.3 4.3e-29 101.7 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KIK67319.1 - 2.9e-27 96.0 7.5 2.9e-27 96.0 7.5 4.1 4 0 0 4 4 4 1 Up-frameshift suppressor 2 Cytadhesin_P30 PF07271.11 KIK67319.1 - 5.9 6.4 5.5 0.41 10.2 0.2 1.7 2 0 0 2 2 2 0 Cytadhesin P30/P32 Pkinase PF00069.25 KIK67320.1 - 1.5e-40 139.3 0.0 1.5e-39 136.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67320.1 - 3.5e-18 65.8 0.0 4e-16 59.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KIK67320.1 - 7.3e-06 26.1 0.1 9.3e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK67320.1 - 0.00089 18.7 0.0 0.97 8.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DUF1679 PF07914.11 KIK67320.1 - 0.0042 16.0 0.0 0.0066 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 KIK67320.1 - 0.0084 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK67320.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cullin PF00888.22 KIK67321.1 - 2.3e-113 379.9 1.4 3.2e-113 379.5 1.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK67321.1 - 1.5e-21 76.2 0.3 9.4e-21 73.6 0.4 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain SNase PF00565.17 KIK67322.1 - 1.1e-52 177.1 0.0 3.8e-19 69.2 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KIK67322.1 - 1.3e-19 70.4 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KIK67322.1 - 0.0038 17.7 0.0 0.026 15.0 0.0 2.4 2 0 0 2 2 2 1 Agenet domain Peptidase_S41 PF03572.18 KIK67323.1 - 0.0001 21.9 0.0 0.00026 20.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 HAD_2 PF13419.6 KIK67324.1 - 6.1e-10 39.5 0.0 7.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK67324.1 - 1.3e-07 32.2 0.0 1.7e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK67324.1 - 5.9e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like T6SS_Vgr PF13296.6 KIK67324.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative type VI secretion system Rhs element Vgr Ribosomal_S6 PF01250.17 KIK67325.1 - 1.4e-20 73.4 0.0 1.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 RRM_2 PF04059.12 KIK67327.1 - 1.2e-34 118.4 1.5 1.6e-34 118.0 1.5 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KIK67327.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KIK67327.1 - 0.0099 16.1 0.4 0.023 14.9 0.4 1.6 1 1 0 1 1 1 1 BRCA1-associated protein 2 Form_Nir_trans PF01226.17 KIK67328.1 - 9.6e-75 251.0 20.9 1.1e-74 250.8 20.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Abhydrolase_3 PF07859.13 KIK67329.1 - 6.1e-21 75.2 0.0 8.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK67329.1 - 1.4e-10 40.6 0.0 2.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3128 PF11326.8 KIK67330.1 - 1.5e-23 83.0 2.0 2.2e-23 82.4 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MCM PF00493.23 KIK67331.1 - 2e-99 331.2 0.0 3.1e-99 330.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK67331.1 - 5.5e-39 132.9 0.0 9.4e-39 132.1 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KIK67331.1 - 3.8e-32 111.7 39.3 7.8e-32 110.7 37.0 2.5 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KIK67331.1 - 1.3e-26 92.8 0.7 4.3e-26 91.2 0.7 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK67331.1 - 8.2e-13 48.8 0.0 2.9e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK67331.1 - 1.3e-07 31.2 0.0 4.1e-06 26.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIK67331.1 - 6e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SelR PF01641.18 KIK67331.1 - 0.00059 19.9 0.2 0.13 12.3 0.1 2.7 2 0 0 2 2 2 1 SelR domain AAA_3 PF07726.11 KIK67331.1 - 0.0012 18.8 0.1 0.013 15.4 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK67331.1 - 0.0022 17.7 0.1 0.019 14.7 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 KIK67331.1 - 0.011 15.9 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CHCH PF06747.13 KIK67332.1 - 1.3e-08 34.7 1.5 2.6e-08 33.8 1.5 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KIK67332.1 - 0.033 14.6 1.4 0.062 13.7 1.4 1.5 1 0 0 1 1 1 0 GCK domain PX PF00787.24 KIK67333.1 - 1.8e-26 92.4 0.0 2.3e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 PX domain SGL PF08450.12 KIK67334.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIK67334.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Flavin_Reduct PF01613.18 KIK67335.1 - 2.6e-26 92.5 0.1 3.8e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KIK67335.1 - 0.14 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 KIK67335.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Fe-ADH PF00465.19 KIK67336.1 - 5.1e-62 209.8 0.0 2e-61 207.9 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIK67336.1 - 9.6e-16 58.2 0.0 1.5e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.21 KIK67337.1 - 7.9e-47 159.6 2.1 1.5e-46 158.6 2.1 1.4 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK67337.1 - 1.1e-08 35.1 0.0 2.7e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF2855 PF11017.8 KIK67337.1 - 0.039 13.7 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Sec7 PF01369.20 KIK67338.1 - 1.8e-35 122.3 0.0 2.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KIK67338.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 PH domain DFF40 PF09230.10 KIK67339.1 - 3.2 7.3 8.7 1.5 8.4 6.4 1.6 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa GATA PF00320.27 KIK67340.1 - 0.00066 19.2 0.4 0.0011 18.5 0.4 1.4 1 0 0 1 1 1 1 GATA zinc finger SIR4_SID PF16991.5 KIK67340.1 - 0.072 13.1 0.3 0.078 13.0 0.3 1.1 1 0 0 1 1 1 0 Sir4 SID domain Ssl1 PF04056.14 KIK67342.1 - 4.9e-71 238.5 0.0 1.5e-70 236.9 0.0 1.7 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KIK67342.1 - 9.9e-16 57.7 13.4 9.9e-16 57.7 13.4 3.1 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 KIK67342.1 - 9.2e-13 48.8 0.0 2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KIK67342.1 - 0.00066 19.3 5.3 0.64 9.5 6.4 2.3 2 0 0 2 2 2 2 Transcription factor Tfb4 zf-HIT PF04438.16 KIK67342.1 - 0.0045 16.8 1.1 0.0045 16.8 1.1 3.5 5 0 0 5 5 5 1 HIT zinc finger IBR PF01485.21 KIK67342.1 - 1.8 8.9 17.7 0.031 14.5 8.4 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain IGPS PF00218.21 KIK67343.1 - 9e-92 306.8 0.0 1e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 KIK67343.1 - 0.00091 19.0 0.2 0.0016 18.2 0.2 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 KIK67343.1 - 0.0098 15.1 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KIK67343.1 - 0.028 13.9 0.1 0.078 12.4 0.0 1.7 2 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KIK67343.1 - 0.069 12.4 0.2 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PALP PF00291.25 KIK67344.1 - 4.7e-78 262.6 0.1 6.5e-78 262.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KIK67344.1 - 2.6e-45 152.1 0.3 1.7e-24 85.4 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase NDUF_B12 PF08122.12 KIK67345.1 - 5.8e-20 71.1 0.3 6.3e-20 71.0 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family PHD PF00628.29 KIK67346.1 - 3e-11 43.0 7.4 5e-11 42.3 7.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KIK67346.1 - 0.02 14.9 0.9 0.044 13.8 0.9 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger DUF4890 PF16231.5 KIK67346.1 - 0.088 13.3 0.2 0.088 13.3 0.2 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4890) PHD_2 PF13831.6 KIK67346.1 - 0.099 12.2 3.9 0.17 11.4 3.9 1.4 1 0 0 1 1 1 0 PHD-finger DUF3866 PF12982.7 KIK67346.1 - 0.2 10.7 0.3 0.32 10.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) zf-UDP PF14569.6 KIK67346.1 - 0.24 11.5 1.6 0.48 10.6 1.6 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Vps8 PF12816.7 KIK67347.1 - 4.8e-65 218.8 0.3 1.3e-64 217.4 0.1 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 PQQ_3 PF13570.6 KIK67347.1 - 0.0046 17.4 1.1 0.18 12.3 0.2 2.9 2 0 0 2 2 2 1 PQQ-like domain Clathrin PF00637.20 KIK67347.1 - 0.0078 16.1 0.1 0.2 11.5 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.32 KIK67347.1 - 0.02 15.8 0.8 2.2 9.3 0.1 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK67347.1 - 0.03 14.6 0.0 0.56 10.6 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain COG2 PF06148.11 KIK67348.1 - 3.7e-25 88.5 3.5 3.7e-25 88.5 3.5 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 KIK67348.1 - 5.2e-25 88.3 0.0 5.3e-24 85.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) DFF-C PF09033.10 KIK67348.1 - 0.0032 17.4 0.9 0.014 15.3 0.7 2.2 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain Vps51 PF08700.11 KIK67348.1 - 0.0078 16.3 0.4 0.026 14.6 0.4 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 KIK67348.1 - 0.035 13.4 2.1 0.073 12.3 2.1 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KIK67348.1 - 2.1 6.8 8.5 1.3 7.5 5.8 2.0 2 1 0 2 2 2 0 Centromere/kinetochore Zw10 Hemerythrin PF01814.23 KIK67349.1 - 6e-15 56.0 4.0 6e-15 56.0 4.0 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain F-box PF00646.33 KIK67350.1 - 0.17 11.8 0.7 0.49 10.3 0.2 2.1 2 0 0 2 2 2 0 F-box domain DUF1168 PF06658.12 KIK67352.1 - 7.3e-38 129.5 22.4 1.9e-37 128.1 22.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Sybindin PF04099.12 KIK67356.1 - 1.9e-20 73.2 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.23 KIK67357.1 - 3.9e-61 206.7 0.2 5.6e-61 206.2 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK67357.1 - 1.6e-20 73.5 0.1 8.3e-20 71.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK67357.1 - 2e-08 34.5 0.0 7.8e-08 32.5 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK67357.1 - 5.6e-05 22.5 0.1 0.00013 21.2 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Mito_carr PF00153.27 KIK67358.1 - 6.3e-15 54.9 0.0 4.7e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Zn_clus PF00172.18 KIK67359.1 - 2.6e-07 30.6 5.7 6.1e-07 29.4 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alg14 PF08660.11 KIK67360.1 - 5.2e-57 192.6 0.0 6.9e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like GLTSCR1 PF15249.6 KIK67361.1 - 1.6e-21 76.7 0.0 2.6e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein CENP-F_N PF10481.9 KIK67361.1 - 0.018 14.7 1.0 0.047 13.3 0.4 1.9 2 0 0 2 2 2 0 Cenp-F N-terminal domain SprA_N PF14349.6 KIK67361.1 - 0.1 11.4 0.1 0.18 10.6 0.1 1.4 1 1 0 1 1 1 0 Motility related/secretion protein FliT PF05400.13 KIK67361.1 - 0.12 13.2 2.4 0.29 12.0 2.4 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Voltage_CLC PF00654.20 KIK67362.1 - 5.3e-90 302.2 20.6 5.3e-90 302.2 20.6 2.0 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIK67362.1 - 0.15 12.5 0.1 5.7 7.5 0.0 2.7 2 0 0 2 2 2 0 CBS domain LSM PF01423.22 KIK67363.1 - 1.6e-14 53.3 0.2 2.1e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KIK67363.1 - 0.026 14.6 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KIK67363.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3337 PF11816.8 KIK67364.1 - 1.8e-51 174.5 0.1 4e-51 173.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KIK67364.1 - 2.9e-20 72.2 22.5 7.8e-07 29.7 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KIK67364.1 - 0.011 14.5 3.6 0.67 8.5 0.1 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK67364.1 - 0.018 14.1 0.0 0.038 12.9 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK67364.1 - 0.028 14.7 0.0 1.1 9.6 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KIK67364.1 - 0.15 10.9 0.4 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RAWUL PF16207.5 KIK67364.1 - 0.15 12.7 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad10 PF03834.14 KIK67365.1 - 3.4e-39 133.4 0.0 1.3e-38 131.5 0.0 1.9 1 1 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KIK67365.1 - 1.1e-07 32.3 0.0 2.6e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KIK67365.1 - 0.00029 20.9 0.0 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Mg_trans_NIPA PF05653.14 KIK67366.1 - 1.8e-18 66.7 11.8 8.8e-10 38.2 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIK67366.1 - 0.00022 21.4 7.9 0.00022 21.4 7.9 3.9 3 2 1 4 4 4 2 EamA-like transporter family OAD_gamma PF04277.13 KIK67366.1 - 0.037 14.6 0.1 1.7 9.3 0.1 2.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MLTD_N PF06474.12 KIK67366.1 - 0.23 11.7 2.4 7.6 6.8 0.6 2.8 2 0 0 2 2 2 0 MltD lipid attachment motif Amidohydro_3 PF07969.11 KIK67367.1 - 8.2e-12 45.3 0.1 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK67367.1 - 3.9e-09 36.3 0.0 2.4e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family AA_permease_N PF08403.10 KIK67367.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF4365 PF14280.6 KIK67368.1 - 0.13 12.2 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4365) Hist_deacetyl PF00850.19 KIK67369.1 - 4e-87 292.6 0.0 5.8e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KIK67369.1 - 4.9e-38 130.7 0.0 6.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Tetraspanin PF00335.20 KIK67371.1 - 3e-06 27.1 10.0 3e-06 27.1 10.0 1.9 1 1 1 2 2 2 1 Tetraspanin family EI24 PF07264.11 KIK67371.1 - 0.15 12.3 8.6 0.47 10.7 8.6 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) CitMHS PF03600.16 KIK67371.1 - 0.74 9.0 9.4 0.22 10.7 6.3 1.6 1 1 1 2 2 2 0 Citrate transporter DUF4064 PF13273.6 KIK67371.1 - 2.1 8.7 14.9 0.37 11.1 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1746 PF08508.10 KIK67372.1 - 5.5e-10 39.6 4.9 1.3e-09 38.4 4.9 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) UPF0203 PF05254.12 KIK67373.1 - 0.0006 20.0 1.5 0.0014 18.8 1.5 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CX9C PF16860.5 KIK67373.1 - 0.00083 19.3 0.6 0.076 13.0 0.1 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KIK67373.1 - 0.033 14.2 1.0 0.1 12.6 0.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 KIK67373.1 - 0.043 14.3 2.3 0.64 10.5 0.3 2.1 1 1 1 2 2 2 0 GCK domain Capsid_VP7 PF17071.5 KIK67374.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Outer capsid protein VP7 Ribosomal_S8e PF01201.22 KIK67376.1 - 6.2e-49 165.7 0.1 1.1e-48 164.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e Fungal_trans PF04082.18 KIK67377.1 - 2.1e-12 46.6 0.3 3.5e-12 45.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK67377.1 - 1.6e-08 34.5 12.7 2.6e-08 33.8 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KIK67377.1 - 4.5 7.8 8.0 24 5.5 7.8 2.1 1 1 1 2 2 2 0 Potato type II proteinase inhibitor family Ribosom_S12_S23 PF00164.25 KIK67378.1 - 2.4e-49 165.7 1.1 3e-49 165.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transglut_core PF01841.19 KIK67379.1 - 5.6e-09 36.5 0.0 1.1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KIK67379.1 - 0.22 11.0 0.0 4.5 6.8 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain CTP_transf_1 PF01148.20 KIK67380.1 - 1.7e-72 244.4 19.9 2.5e-72 243.9 19.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Topoisom_I PF01028.20 KIK67381.1 - 5.9e-99 330.0 5.1 2.1e-98 328.2 5.1 2.0 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KIK67381.1 - 2.4e-96 321.3 1.2 2.4e-96 321.3 1.2 4.0 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KIK67381.1 - 5.8e-37 125.4 0.6 2.9e-36 123.2 0.6 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain tRNA-synt_1b PF00579.25 KIK67382.1 - 1e-75 254.8 0.0 1.4e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EMP70 PF02990.16 KIK67383.1 - 5.7e-195 648.9 1.1 5.7e-195 648.9 1.1 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 TMEM40 PF15817.5 KIK67383.1 - 8.8 6.1 7.6 6.2 6.6 4.6 2.3 2 0 0 2 2 2 0 Transmembrane protein 40 family TGT PF01702.18 KIK67384.1 - 6.8e-113 377.4 0.0 8.6e-74 248.8 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase GPI-anchored PF10342.9 KIK67385.1 - 0.00084 20.1 0.0 0.0011 19.7 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DEAD PF00270.29 KIK67386.1 - 2.5e-38 131.6 0.0 9.1e-38 129.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK67386.1 - 1.4e-23 83.3 0.1 7.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KIK67386.1 - 8.1e-20 70.8 4.3 3.6e-19 68.8 4.3 2.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain F-box-like PF12937.7 KIK67387.1 - 3.6e-09 36.4 3.4 1.2e-08 34.6 3.4 2.0 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 KIK67387.1 - 0.22 11.7 0.9 0.68 10.2 0.1 2.3 2 0 0 2 2 2 0 FNIP Repeat DASH_Duo1 PF08651.10 KIK67388.1 - 1.2e-16 60.2 0.2 4.8e-16 58.3 0.2 1.9 1 1 0 1 1 1 1 DASH complex subunit Duo1 Vfa1 PF08432.10 KIK67388.1 - 1.2 9.5 9.8 2.1 8.6 3.7 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CAF-1_p150 PF11600.8 KIK67388.1 - 2.8 7.6 28.5 0.11 12.2 17.9 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cauli_VI PF01693.16 KIK67389.1 - 0.00052 20.3 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 Caulimovirus viroplasmin WGR PF05406.15 KIK67389.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 WGR domain ATG27 PF09451.10 KIK67390.1 - 2.2e-63 214.6 0.0 2.6e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KIK67390.1 - 5.8e-05 23.2 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 KIK67390.1 - 9.8e-05 21.6 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Josephin PF02099.17 KIK67391.1 - 3.2e-47 160.7 0.0 6e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Josephin RAP80_UIM PF18282.1 KIK67391.1 - 0.0071 16.1 3.9 0.02 14.6 3.9 1.8 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif 3-PAP PF12578.8 KIK67391.1 - 0.095 12.4 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 Myotubularin-associated protein UIM PF02809.20 KIK67391.1 - 0.56 10.2 38.3 0.22 11.5 0.4 4.7 4 0 0 4 4 4 0 Ubiquitin interaction motif BUD22 PF09073.10 KIK67391.1 - 5.8 6.2 12.1 7.9 5.7 12.1 1.1 1 0 0 1 1 1 0 BUD22 Amidohydro_1 PF01979.20 KIK67392.1 - 2.2e-38 132.5 0.0 2.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK67392.1 - 1.7e-13 50.9 0.0 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KIK67392.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase FtsJ PF01728.19 KIK67392.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Yippee-Mis18 PF03226.14 KIK67393.1 - 1.4e-10 41.3 0.0 1.7e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 KIK67393.1 - 0.11 12.4 0.3 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease HECT_2 PF09814.9 KIK67393.1 - 0.45 9.3 3.3 0.26 10.1 0.4 1.9 1 1 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding LSM PF01423.22 KIK67394.1 - 4.1e-17 61.6 0.1 5.7e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK67394.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain RabGAP-TBC PF00566.18 KIK67395.1 - 1.1e-51 175.6 0.2 1.8e-51 174.8 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ZapB PF06005.12 KIK67395.1 - 0.0085 16.5 5.2 2.1 8.9 0.0 2.7 2 1 0 2 2 2 2 Cell division protein ZapB ATG16 PF08614.11 KIK67395.1 - 1.5 9.0 17.0 3.9 7.7 7.1 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIK67395.1 - 2 9.0 12.4 0.56 10.7 6.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIK67395.1 - 4.6 7.1 12.3 3.5 7.5 0.5 3.3 2 1 1 3 3 3 0 Septum formation initiator GatB_N PF02934.15 KIK67396.1 - 1.3e-105 352.7 0.0 2e-105 352.1 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KIK67396.1 - 9.4e-27 93.7 0.1 3.2e-26 92.0 0.1 1.9 1 1 0 1 1 1 1 GatB domain ABC1 PF03109.16 KIK67397.1 - 1.3e-31 109.2 0.0 2.5e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KIK67397.1 - 1.2e-05 25.0 0.1 9.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family PC4 PF02229.16 KIK67398.1 - 5.6e-23 80.3 0.2 1.1e-22 79.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) BEX PF04538.12 KIK67398.1 - 1.5 9.4 8.7 2.4 8.8 8.7 1.5 1 1 0 1 1 1 0 Brain expressed X-linked like family Neur_chan_memb PF02932.16 KIK67398.1 - 2.9 7.9 4.8 3.5 7.6 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 KIK67399.1 - 1.7e-97 326.8 0.0 1.7e-97 326.8 0.0 6.5 7 1 0 7 7 7 2 Domain of Unknown Function (DUF913) HECT PF00632.25 KIK67399.1 - 1.5e-92 310.4 0.0 8.6e-92 307.9 0.0 2.3 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KIK67399.1 - 6.2e-86 289.0 2.7 6.2e-86 289.0 2.7 5.2 5 1 1 6 6 6 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KIK67399.1 - 2.1e-28 96.8 17.3 2e-11 42.9 0.9 4.1 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KIK67399.1 - 1.3e-10 41.0 0.0 3.4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF3361 PF11841.8 KIK67399.1 - 0.026 14.5 0.2 24 4.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) ADH_zinc_N PF00107.26 KIK67400.1 - 1.6e-32 112.2 0.3 2.4e-32 111.6 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK67400.1 - 3.2e-18 67.1 0.0 5.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK67400.1 - 1.4e-05 24.9 0.0 6e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIK67400.1 - 0.044 13.2 0.4 0.067 12.6 0.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Het-C PF07217.11 KIK67402.1 - 3.3e-219 729.1 0.0 4.1e-219 728.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C AMP-binding PF00501.28 KIK67403.1 - 3.3e-82 276.3 0.0 4.2e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK67403.1 - 1.8e-12 48.0 0.1 4.8e-12 46.7 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RNA_pol_A_bac PF01000.26 KIK67404.1 - 1.6e-30 105.7 0.0 2.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIK67404.1 - 2.6e-19 68.4 0.0 4.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 KIK67404.1 - 0.14 11.8 0.3 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF22 MS_channel PF00924.18 KIK67405.1 - 3.3e-24 85.6 0.7 6.9e-24 84.5 0.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 KIK67405.1 - 0.16 11.9 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain RIBIOP_C PF04950.12 KIK67406.1 - 4.4e-105 351.3 0.0 7e-105 350.6 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIK67406.1 - 1e-19 70.4 0.0 2.5e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CDC45 PF02724.14 KIK67406.1 - 4 5.6 7.1 8.1 4.6 7.1 1.5 1 0 0 1 1 1 0 CDC45-like protein SNARE PF05739.19 KIK67408.1 - 1.2e-13 50.8 0.9 2.8e-13 49.7 0.9 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KIK67408.1 - 0.00019 21.1 2.2 0.00019 21.1 2.2 1.9 2 1 0 2 2 2 1 Syntaxin Shisa PF13908.6 KIK67408.1 - 0.04 14.2 0.2 0.082 13.2 0.2 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4407 PF14362.6 KIK67408.1 - 0.12 11.7 3.8 0.19 11.1 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MCPsignal PF00015.21 KIK67408.1 - 0.13 12.1 2.8 0.28 11.0 1.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4pol PF14260.6 KIK67409.1 - 0.0021 18.5 3.6 0.035 14.6 0.9 2.2 2 0 0 2 2 2 2 C4-type zinc-finger of DNA polymerase delta Fe_hyd_lg_C PF02906.14 KIK67410.1 - 3.6e-58 197.1 0.0 5.8e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF4421 PF14391.6 KIK67411.1 - 0.28 10.5 0.0 0.38 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) Aa_trans PF01490.18 KIK67413.1 - 5.1e-69 232.9 25.0 5.7e-69 232.8 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PrgI PF12666.7 KIK67413.1 - 0.52 11.0 0.1 0.52 11.0 0.1 3.3 4 2 0 4 4 4 0 PrgI family protein B12D PF06522.11 KIK67413.1 - 2.8 7.8 4.0 39 4.2 0.6 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit GHMP_kinases_N PF00288.26 KIK67414.1 - 2.4e-14 53.3 2.1 5.7e-14 52.1 2.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK67414.1 - 4.5e-10 39.8 0.0 1.4e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Phage_G PF02306.15 KIK67414.1 - 0.061 13.0 0.2 2.6 7.8 0.1 2.7 2 1 0 2 2 2 0 Major spike protein (G protein) Ferrochelatase PF00762.19 KIK67415.1 - 2e-103 345.8 0.0 2.3e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 KIK67415.1 - 0.0013 19.0 0.1 6.4 7.2 0.0 3.2 3 0 0 3 3 3 2 CbiX Glyco_hydro_70 PF02324.16 KIK67415.1 - 0.022 13.0 0.0 0.03 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Fer2_3 PF13085.6 KIK67418.1 - 1.2e-33 115.4 0.0 1.8e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KIK67418.1 - 3.3e-10 40.4 7.4 3.3e-10 40.4 7.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIK67418.1 - 6e-07 29.5 4.4 6e-07 29.5 4.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIK67418.1 - 6.2e-07 29.8 7.8 6.2e-07 29.8 7.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIK67418.1 - 0.00058 20.4 5.4 0.00058 20.4 5.4 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KIK67418.1 - 0.00076 19.4 3.1 0.0017 18.2 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KIK67418.1 - 0.01 16.0 0.2 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Trm112p PF03966.16 KIK67419.1 - 8.7e-21 74.3 0.2 1.1e-20 74.0 0.2 1.1 1 0 0 1 1 1 1 Trm112p-like protein RNase_PH PF01138.21 KIK67420.1 - 8.8e-21 74.8 0.0 1.3e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK67420.1 - 1.8e-08 34.2 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PHD PF00628.29 KIK67421.1 - 1.2e-06 28.3 5.4 1.2e-06 28.3 5.4 3.6 4 1 0 4 4 4 1 PHD-finger Glyco_hydro_2_C PF02836.17 KIK67422.1 - 4.6e-103 344.5 0.0 6.2e-103 344.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KIK67422.1 - 1.6e-65 221.1 0.0 3e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KIK67422.1 - 9e-40 136.3 0.1 1.9e-39 135.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KIK67422.1 - 8.1e-23 80.7 0.0 2.6e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KIK67422.1 - 1.1e-08 35.7 0.5 5.5e-08 33.5 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 SRP14 PF02290.15 KIK67423.1 - 1.7e-24 86.0 0.1 1.7e-24 86.0 0.1 2.0 2 0 0 2 2 2 1 Signal recognition particle 14kD protein SARS_lipid_bind PF09399.10 KIK67423.1 - 0.047 13.9 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 SARS lipid binding protein DUF2917 PF11142.8 KIK67423.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Spindle_Spc25 PF08234.12 KIK67424.1 - 2.1e-22 79.1 0.9 4.1e-22 78.2 0.1 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 BST2 PF16716.5 KIK67424.1 - 0.0044 17.6 8.7 0.01 16.4 8.7 1.6 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 MecA_N PF05223.11 KIK67424.1 - 0.062 13.6 3.5 0.15 12.4 3.5 1.7 1 1 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain DUF3450 PF11932.8 KIK67424.1 - 0.1 11.9 9.5 0.14 11.4 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KIK67424.1 - 0.15 11.1 8.5 0.19 10.8 8.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 KIK67424.1 - 0.22 11.9 9.0 0.38 11.2 9.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ACR_tran PF00873.19 KIK67424.1 - 0.32 8.6 2.6 0.41 8.2 2.6 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF4407 PF14362.6 KIK67424.1 - 0.33 10.3 10.3 0.43 9.9 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 KIK67424.1 - 0.53 10.7 16.7 1.3 9.4 15.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CLZ PF16526.5 KIK67424.1 - 1.2 9.6 9.6 1.5 9.2 0.8 3.1 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 KIK67424.1 - 1.7 9.2 15.0 2.1 8.9 13.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region zf-RING_2 PF13639.6 KIK67425.1 - 5.5e-09 36.2 1.4 2.6e-07 30.8 0.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK67425.1 - 1.6e-07 31.0 2.6 1.8e-06 27.7 0.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK67425.1 - 1.9e-07 31.2 0.4 1.8e-06 28.1 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIK67425.1 - 3.8e-06 26.5 0.2 0.0019 17.9 0.0 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KIK67425.1 - 2.6e-05 24.0 0.3 0.00022 21.0 0.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK67425.1 - 6.7e-05 22.7 0.6 0.00015 21.5 0.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK67425.1 - 0.00037 20.4 0.7 0.00064 19.6 0.1 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIK67425.1 - 0.0047 16.9 0.1 0.012 15.6 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KIK67425.1 - 0.0089 16.0 1.1 0.0089 16.0 1.1 3.3 2 1 1 3 3 3 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIK67425.1 - 0.014 15.0 0.7 0.037 13.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KIK67425.1 - 0.022 14.6 0.6 0.022 14.6 0.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIK67425.1 - 0.14 12.3 3.1 1.1 9.4 3.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 KIK67425.1 - 0.28 10.9 1.1 0.69 9.6 1.1 1.6 1 0 0 1 1 1 0 P-11 zinc finger GTP_EFTU PF00009.27 KIK67426.1 - 8.6e-19 67.8 0.0 1.8e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIK67426.1 - 2.3e-06 27.9 3.4 3.7e-06 27.2 0.5 3.0 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KIK67426.1 - 1.3e-05 25.5 0.0 4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KIK67426.1 - 0.046 13.5 0.8 4.9 6.9 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KIK67426.1 - 0.099 12.7 0.2 0.6 10.2 0.1 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase SKN1 PF03935.15 KIK67427.1 - 3.3e-190 632.7 0.4 3.8e-190 632.5 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Mnd1 PF03962.15 KIK67428.1 - 2.1e-30 104.8 1.9 4.4e-30 103.8 0.2 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KIK67428.1 - 1.6e-06 28.1 0.2 3.6e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain MPS2 PF17060.5 KIK67428.1 - 0.00022 20.6 1.0 0.00027 20.3 1.0 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 FUR PF01475.19 KIK67428.1 - 0.0015 18.7 0.1 0.0094 16.1 0.0 2.0 2 0 0 2 2 2 1 Ferric uptake regulator family Spc7 PF08317.11 KIK67428.1 - 0.0089 14.9 5.3 0.017 14.0 5.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein SMK-1 PF04802.15 KIK67428.1 - 0.024 14.5 0.2 0.062 13.1 0.1 1.8 1 1 1 2 2 2 0 Component of IIS longevity pathway SMK-1 Fungal_trans PF04082.18 KIK67429.1 - 5.3e-08 32.2 0.0 8.8e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK67429.1 - 2.2e-07 30.9 12.0 4.1e-07 30.0 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain W2 PF02020.18 KIK67430.1 - 1.1e-19 70.3 1.7 2.1e-19 69.4 0.2 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PP2C PF00481.21 KIK67431.1 - 1.9e-62 211.2 0.1 1.3e-46 159.3 0.1 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.21 KIK67432.1 - 7.1e-65 219.2 0.2 1.2e-48 166.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KIK67432.1 - 0.002 18.1 0.1 0.0089 16.0 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Choline_transpo PF04515.12 KIK67433.1 - 8.5e-80 268.4 13.9 8.5e-80 268.4 13.9 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Claudin_3 PF06653.11 KIK67434.1 - 0.084 12.8 10.4 3.3 7.6 5.0 3.0 2 1 1 3 3 3 0 Tight junction protein, Claudin-like DUF1218 PF06749.12 KIK67434.1 - 0.47 11.0 9.6 2.8 8.5 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF5134 PF17197.4 KIK67434.1 - 0.58 10.0 7.1 0.2 11.5 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Glyco_hydro_18 PF00704.28 KIK67435.1 - 1.1e-80 271.8 0.0 1.4e-80 271.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Oxidored_q6 PF01058.22 KIK67437.1 - 2.5e-22 79.1 0.1 4e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.25 KIK67438.1 - 4.9e-51 173.6 0.0 1.6e-36 126.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67438.1 - 1.3e-22 80.3 0.0 2.4e-22 79.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK67438.1 - 9.1e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK67438.1 - 0.005 15.8 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK67438.1 - 0.023 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK67438.1 - 0.068 12.8 0.0 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK67438.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK67438.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HhH-GPD PF00730.25 KIK67439.1 - 8.1e-15 55.2 0.0 1.4e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Inhibitor_I9 PF05922.16 KIK67440.1 - 6.3e-05 23.6 0.0 0.00022 21.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 SRP68 PF16969.5 KIK67441.1 - 9.8e-72 242.7 5.1 9.8e-72 242.7 5.1 2.0 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 SLAC1 PF03595.17 KIK67442.1 - 2e-73 247.5 48.6 2.3e-73 247.3 48.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PAP2 PF01569.21 KIK67444.1 - 2.5e-34 118.0 2.0 4.6e-34 117.1 2.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 KIK67444.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5510) CI-B14_5a PF07347.12 KIK67445.1 - 0.034 14.0 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) RRM_1 PF00076.22 KIK67446.1 - 2.4e-14 52.9 0.1 1.1e-05 25.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK67446.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif FMN_dh PF01070.18 KIK67447.1 - 2.3e-120 401.8 0.0 2.8e-120 401.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK67447.1 - 7.5e-19 67.7 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KIK67447.1 - 0.0001 21.4 0.2 0.00028 20.0 0.1 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIK67447.1 - 0.00012 21.3 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KIK67447.1 - 0.00033 20.0 0.0 0.86 8.9 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KIK67447.1 - 0.047 13.1 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 KIK67447.1 - 0.08 12.4 0.2 0.51 9.7 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 KIK67447.1 - 0.16 11.1 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PEP_mutase PF13714.6 KIK67448.1 - 6.4e-44 150.2 3.4 8.4e-44 149.8 3.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIK67448.1 - 2.9e-17 62.4 0.4 4e-17 61.9 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 KIK67448.1 - 0.046 12.9 0.2 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like PEP_mutase PF13714.6 KIK67449.1 - 3.5e-44 151.0 3.6 4.3e-44 150.8 3.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIK67449.1 - 9.3e-17 60.7 0.7 1.3e-16 60.2 0.7 1.2 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 KIK67449.1 - 0.024 13.9 0.3 0.071 12.3 0.1 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like PI3_PI4_kinase PF00454.27 KIK67450.1 - 4.7e-32 111.8 0.0 3.1e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Lactamase_B PF00753.27 KIK67451.1 - 9.2e-15 55.2 0.1 1.6e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK67451.1 - 0.00017 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain COesterase PF00135.28 KIK67452.1 - 6.5e-65 219.9 0.0 9.5e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK67452.1 - 2e-13 50.7 0.1 3.5e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Vps23_core PF09454.10 KIK67452.1 - 0.12 12.4 0.3 0.49 10.4 0.1 1.9 2 0 0 2 2 2 0 Vps23 core domain Say1_Mug180 PF10340.9 KIK67452.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase DUF747 PF05346.11 KIK67453.1 - 7.5e-115 383.8 3.6 9.4e-115 383.5 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family BH3 PF15285.6 KIK67453.1 - 0.15 11.9 0.3 0.41 10.5 0.3 1.7 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting F-box-like PF12937.7 KIK67455.1 - 1.3e-05 25.0 5.2 0.00036 20.4 5.2 3.0 1 1 0 1 1 1 1 F-box-like AMP-binding PF00501.28 KIK67456.1 - 8.9e-46 156.3 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIK67456.1 - 1e-06 28.6 0.1 2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIK67456.1 - 0.0069 17.3 0.1 0.017 16.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSF73-100_C PF11718.8 KIK67458.1 - 1.7e-68 230.4 0.2 2.5e-68 229.9 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KIK67458.1 - 6.5e-30 103.7 0.0 1.6e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KIK67458.1 - 1.8e-17 63.4 0.0 5e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KIK67458.1 - 3.3e-17 62.2 0.2 6.6e-17 61.2 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KIK67458.1 - 1.8e-11 44.4 1.4 1.8e-11 44.4 1.4 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK67458.1 - 3.9e-07 29.8 1.1 2.3e-06 27.3 0.3 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIK67458.1 - 0.0036 17.2 0.4 0.0036 17.2 0.4 3.0 3 2 0 3 3 3 1 Beta-lactamase superfamily domain Glyco_hydro_76 PF03663.14 KIK67462.1 - 1.7e-36 126.5 19.3 2.9e-36 125.8 19.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KIK67462.1 - 0.0028 16.8 0.1 0.0044 16.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Sec7 PF01369.20 KIK67463.1 - 8.8e-31 107.0 0.6 3e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KIK67463.1 - 9.3e-28 97.0 0.0 2e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK67463.1 - 0.0028 18.1 0.0 0.0085 16.6 0.0 1.8 1 1 0 1 1 1 1 PH domain Lzipper-MIP1 PF14389.6 KIK67463.1 - 0.12 12.7 1.0 0.9 9.9 0.2 2.7 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 IBN_N PF03810.19 KIK67465.1 - 4.9e-07 29.6 1.9 0.00029 20.7 0.4 4.7 3 2 1 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KIK67465.1 - 1.1e-05 24.3 0.1 0.00026 19.7 0.0 2.7 2 0 0 2 2 2 1 Adaptin N terminal region Xpo1 PF08389.12 KIK67465.1 - 0.00059 19.9 0.1 0.0044 17.1 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein ParcG PF10274.9 KIK67465.1 - 0.003 17.7 0.4 6.4 6.9 0.0 3.6 3 2 1 5 5 5 2 Parkin co-regulated protein API5 PF05918.11 KIK67465.1 - 0.0043 15.9 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 KIK67465.1 - 0.0059 16.8 1.5 0.93 9.9 0.0 4.5 4 0 0 4 4 3 1 HEAT repeat HEAT_2 PF13646.6 KIK67465.1 - 0.028 14.8 0.7 1.5 9.2 0.0 3.9 3 1 0 3 3 3 0 HEAT repeats CRM1_C PF08767.11 KIK67465.1 - 0.038 13.2 0.1 0.11 11.6 0.1 1.7 1 0 0 1 1 1 0 CRM1 C terminal CAS_CSE1 PF03378.15 KIK67465.1 - 0.039 12.4 0.1 0.87 8.0 0.0 2.6 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus Cse1 PF08506.10 KIK67465.1 - 0.05 12.4 0.0 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Cse1 RIX1 PF08167.12 KIK67465.1 - 0.072 12.8 2.9 0.23 11.2 0.1 3.4 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Rit1_C PF17184.4 KIK67465.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Rit1 N-terminal domain CLASP_N PF12348.8 KIK67465.1 - 0.16 11.5 0.2 57 3.2 0.0 3.7 4 0 0 4 4 4 0 CLASP N terminal GATA PF00320.27 KIK67466.1 - 3.2e-18 65.1 3.1 5.3e-18 64.3 3.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Peptidase_A22B PF04258.13 KIK67467.1 - 1e-62 212.2 3.6 1.2e-62 212.0 3.6 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KIK67467.1 - 0.00025 20.6 6.8 0.001 18.6 6.8 1.8 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KIK67467.1 - 0.014 14.2 2.1 0.026 13.3 2.1 1.5 1 1 0 1 1 1 0 Presenilin G_glu_transpept PF01019.21 KIK67468.1 - 7e-154 513.4 0.0 8e-154 513.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Rimk_N PF18030.1 KIK67468.1 - 0.031 14.7 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 RimK PreATP-grasp domain CMD PF02627.20 KIK67470.1 - 0.048 13.7 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family HLH PF00010.26 KIK67471.1 - 5.8e-10 39.0 0.2 1.1e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain cNMP_binding PF00027.29 KIK67471.1 - 0.17 11.9 0.0 28 4.9 0.0 2.2 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain O-FucT PF10250.9 KIK67472.1 - 4.5e-11 43.0 0.0 1.1e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FtsH_ext PF06480.15 KIK67472.1 - 0.053 13.9 0.1 0.15 12.5 0.1 1.8 1 0 0 1 1 1 0 FtsH Extracellular WD40 PF00400.32 KIK67473.1 - 6.2e-58 191.4 31.6 2.6e-09 37.5 0.3 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK67473.1 - 9.1e-26 90.0 0.7 2.6e-05 24.4 0.0 6.3 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KIK67473.1 - 4.1e-08 33.6 0.0 7.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KIK67473.1 - 1e-06 28.0 0.0 0.29 10.0 0.0 4.0 3 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK67473.1 - 7.2e-06 24.9 4.0 0.15 10.7 0.3 4.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK67473.1 - 0.00084 19.2 0.1 2.6 8.1 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK67473.1 - 0.052 12.3 0.1 0.91 8.2 0.0 2.8 3 1 0 3 3 3 0 Nup133 N terminal like TFIIIC_delta PF12657.7 KIK67473.1 - 0.082 12.8 0.5 15 5.5 0.0 3.4 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KIK67473.1 - 0.089 10.8 0.0 0.55 8.2 0.0 1.9 2 0 0 2 2 2 0 IKI3 family PQQ_3 PF13570.6 KIK67473.1 - 0.65 10.6 6.2 5.4 7.6 0.9 4.6 5 0 0 5 5 5 0 PQQ-like domain RrnaAD PF00398.20 KIK67474.1 - 1.3e-27 96.6 0.0 3.3e-27 95.2 0.0 1.7 2 1 0 2 2 2 1 Ribosomal RNA adenine dimethylase NAD_binding_2 PF03446.15 KIK67476.1 - 2.5e-30 105.7 0.0 3.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIK67476.1 - 6.4e-24 84.5 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CMD PF02627.20 KIK67477.1 - 2.1e-18 66.1 0.0 2.8e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PhyH PF05721.13 KIK67478.1 - 1.1e-47 163.0 0.0 1.3e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Dioxygenase_C PF00775.21 KIK67479.1 - 8.4e-46 155.7 0.0 1.2e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KIK67479.1 - 3.1e-32 110.3 0.0 5.4e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KIK67479.1 - 0.00029 21.1 0.1 0.0015 18.7 0.0 2.1 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain ACOX PF01756.19 KIK67479.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase DUF4712 PF15830.5 KIK67479.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) BRCT_2 PF16589.5 KIK67480.1 - 1e-09 38.6 0.0 2.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK67480.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK67480.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF3484 PF11983.8 KIK67480.1 - 6.2 8.0 10.8 2.9 9.1 0.9 3.3 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch PH_10 PF15411.6 KIK67481.1 - 1.2e-37 128.9 0.0 2.5e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KIK67481.1 - 4.6e-33 115.0 1.5 7.8e-33 114.2 1.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KIK67481.1 - 2e-18 66.1 0.0 3.9e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 KIK67481.1 - 1.8e-10 40.9 0.1 3.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin She9_MDM33 PF05546.11 KIK67481.1 - 0.11 12.3 2.2 0.23 11.3 0.3 2.1 2 0 0 2 2 2 0 She9 / Mdm33 family Glyco_hydro_63 PF03200.16 KIK67482.1 - 5.4e-08 32.0 9.2 1.6e-06 27.2 0.9 4.0 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Snurportin1 PF11538.8 KIK67482.1 - 0.15 12.3 1.4 0.38 11.0 1.4 1.7 1 0 0 1 1 1 0 Snurportin1 RhoGAP PF00620.27 KIK67483.1 - 1.1e-31 109.7 0.0 2.1e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mito_carr PF00153.27 KIK67484.1 - 2.5e-73 242.1 1.5 4.2e-25 87.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK67484.1 - 0.00029 20.1 0.4 0.3 10.2 0.0 3.3 3 1 0 4 4 4 2 Gammaproteobacterial serine protease HK PF02110.15 KIK67487.1 - 5.3e-75 252.0 3.8 2e-74 250.1 3.8 1.8 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KIK67487.1 - 6.2e-57 191.8 0.2 1.2e-56 190.9 0.2 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KIK67487.1 - 7.8e-05 22.2 0.5 0.00021 20.8 0.2 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase zf-C2H2 PF00096.26 KIK67490.1 - 1.4e-10 41.0 1.4 0.00024 21.4 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK67490.1 - 1.4e-08 34.8 1.7 0.00085 20.0 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK67490.1 - 5.6e-07 29.7 11.2 0.00054 20.3 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 KIK67490.1 - 0.0037 17.1 2.0 0.11 12.4 0.1 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIK67490.1 - 0.0042 17.3 0.1 0.0083 16.4 0.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KIK67490.1 - 0.014 15.7 0.1 0.045 14.1 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KIK67490.1 - 0.029 14.7 0.2 0.047 14.0 0.2 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2 PF00096.26 KIK67491.1 - 1.5e-11 44.1 6.6 2.2e-07 31.0 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK67491.1 - 2.8e-11 43.3 3.5 2.6e-06 27.6 0.6 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK67491.1 - 2.4e-07 31.0 5.4 2.1e-05 25.0 1.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK67491.1 - 0.0002 21.2 3.2 0.0015 18.3 0.4 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF3268 PF11672.8 KIK67491.1 - 0.00083 19.7 0.4 0.00089 19.6 0.4 1.1 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_6 PF13912.6 KIK67491.1 - 0.0036 17.3 4.3 0.0054 16.7 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 KIK67491.1 - 0.0038 17.2 1.9 0.005 16.8 1.3 1.7 1 1 1 2 2 2 1 BED zinc finger DZR PF12773.7 KIK67491.1 - 0.016 15.2 0.3 0.021 14.8 0.3 1.1 1 0 0 1 1 1 0 Double zinc ribbon zf-CHCC PF10276.9 KIK67491.1 - 0.022 14.8 0.6 0.031 14.3 0.2 1.5 2 0 0 2 2 2 0 Zinc-finger domain Ribosomal_S27e PF01667.17 KIK67491.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 PyrI_C PF02748.15 KIK67491.1 - 0.055 13.4 0.7 0.079 12.9 0.0 1.7 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 KIK67491.1 - 0.11 13.0 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Plasmodium_Vir PF05795.11 KIK67492.1 - 0.0038 16.7 8.3 0.0067 15.9 8.3 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Alpha_GJ PF03229.13 KIK67492.1 - 0.0095 16.5 11.0 0.0095 16.5 11.0 3.5 3 1 1 4 4 3 1 Alphavirus glycoprotein J CbtA PF09490.10 KIK67492.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) RIFIN PF02009.16 KIK67492.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Rifin PepSY_TM PF03929.16 KIK67492.1 - 0.015 15.0 0.5 0.025 14.2 0.1 1.5 1 1 1 2 2 2 0 PepSY-associated TM region Amnionless PF14828.6 KIK67492.1 - 0.023 13.6 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 KIK67492.1 - 0.044 13.5 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 KIK67492.1 - 0.088 13.1 0.1 0.24 11.7 0.0 1.8 1 1 1 2 2 2 0 Protein melan-A DUF202 PF02656.15 KIK67492.1 - 0.097 13.1 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) EphA2_TM PF14575.6 KIK67492.1 - 0.2 12.5 0.0 0.54 11.2 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NPR3 PF03666.13 KIK67492.1 - 1.4 7.6 5.5 1.9 7.1 5.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Podoplanin PF05808.11 KIK67492.1 - 2.2 8.4 17.6 4.8 7.3 17.6 1.5 1 0 0 1 1 1 0 Podoplanin TP6A_N PF04406.14 KIK67493.1 - 7.2e-21 73.9 0.1 1.2e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Type IIB DNA topoisomerase AAA_22 PF13401.6 KIK67494.1 - 1.4e-13 51.3 0.0 3.9e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK67494.1 - 1.1e-12 48.7 0.4 4.5e-12 46.7 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK67494.1 - 7.6e-09 36.1 0.0 1.9e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK67494.1 - 7.2e-05 23.2 0.0 0.00034 21.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KIK67494.1 - 0.00014 21.1 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 KIK67494.1 - 0.0004 19.8 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.22 KIK67494.1 - 0.00047 19.4 0.0 0.00075 18.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 KIK67494.1 - 0.00092 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein KAP_NTPase PF07693.14 KIK67494.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain cobW PF02492.19 KIK67494.1 - 0.003 17.2 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KIK67494.1 - 0.0066 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 KIK67494.1 - 0.009 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KIK67494.1 - 0.011 15.7 0.0 0.095 12.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIK67494.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AFG1_ATPase PF03969.16 KIK67494.1 - 0.016 14.1 0.0 0.036 13.0 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KIK67494.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.21 KIK67494.1 - 0.023 14.2 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 KIK67494.1 - 0.029 14.3 0.0 0.077 12.9 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KIK67494.1 - 0.039 13.7 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIK67494.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_PrkA PF08298.11 KIK67494.1 - 0.072 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.22 KIK67494.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK67494.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK67494.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 KIK67494.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GCP_C_terminal PF04130.13 KIK67495.1 - 9.1e-63 212.6 0.3 1.9e-62 211.5 0.3 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIK67495.1 - 3e-07 30.4 0.0 6.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF1917 PF08939.10 KIK67496.1 - 1.4e-24 87.5 2.1 1.4e-24 87.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) YtxH PF12732.7 KIK67496.1 - 0.015 15.9 3.0 0.015 15.9 3.0 2.1 2 1 0 2 2 2 0 YtxH-like protein RR_TM4-6 PF06459.12 KIK67496.1 - 5.4 6.8 15.8 3.7 7.3 9.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PRIMA1 PF16101.5 KIK67497.1 - 0.76 9.8 5.8 2.7 8.0 5.8 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Rer1 PF03248.13 KIK67498.1 - 4e-78 261.0 3.6 4.6e-78 260.8 3.6 1.0 1 0 0 1 1 1 1 Rer1 family Zeta_toxin PF06414.12 KIK67499.1 - 0.0025 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KIK67499.1 - 0.0069 16.8 0.0 0.01 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 KIK67499.1 - 0.038 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Torsin DUF1580 PF07618.11 KIK67499.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) KAP_NTPase PF07693.14 KIK67499.1 - 0.094 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF2791 PF10923.8 KIK67499.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_29 PF13555.6 KIK67499.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIK67499.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 KIK67499.1 - 0.2 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein UPF0029 PF01205.19 KIK67500.1 - 2e-26 92.3 0.0 3.1e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 SSFA2_C PF14723.6 KIK67500.1 - 0.16 11.9 0.1 0.59 10.0 0.1 1.8 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Acetyltransf_1 PF00583.25 KIK67501.1 - 3.1e-10 40.3 0.0 4.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIK67501.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIK67501.1 - 0.00011 22.4 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK67501.1 - 0.00018 22.2 0.0 0.00023 21.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK67501.1 - 0.00022 21.6 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cyclin_N PF00134.23 KIK67502.1 - 1.7e-13 50.4 0.1 2.4e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK67502.1 - 2.8e-07 31.0 0.0 4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin zf-CCCH_2 PF14608.6 KIK67503.1 - 1.7e-17 63.1 33.0 7.4e-06 26.2 5.5 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger TraT PF05818.12 KIK67503.1 - 0.035 13.8 0.4 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Metal_resist PF13801.6 KIK67503.1 - 0.52 10.5 0.1 0.52 10.5 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance zf-CCCH PF00642.24 KIK67503.1 - 10 6.2 24.2 13 5.8 3.2 5.1 3 2 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_16 PF13191.6 KIK67504.1 - 2e-08 34.8 0.1 6.5e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RNA12 PF10443.9 KIK67504.1 - 0.0053 15.6 0.7 2.3 6.9 0.6 2.3 2 0 0 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 KIK67504.1 - 0.009 16.0 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KIK67504.1 - 0.022 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_trans_1_2 PF13524.6 KIK67505.1 - 0.33 11.4 1.8 0.88 10.0 1.8 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 RED_C PF07807.11 KIK67507.1 - 0.003 18.0 2.5 0.011 16.2 2.5 1.9 1 0 0 1 1 1 1 RED-like protein C-terminal region ORC5_C PF14630.6 KIK67508.1 - 2.9e-56 191.1 0.0 4e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus FLILHELTA PF10306.9 KIK67509.1 - 8.5e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KIK67509.1 - 0.00044 20.7 0.1 0.00051 20.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) RSN1_7TM PF02714.15 KIK67510.1 - 2.1e-77 260.1 25.0 4.2e-77 259.2 25.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIK67510.1 - 3.5e-40 138.1 0.0 5.7e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK67510.1 - 6e-35 120.3 0.3 6e-35 120.3 0.3 2.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PriCT_2 PF08707.11 KIK67511.1 - 0.79 10.1 3.3 1.4 9.3 1.2 2.5 2 1 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Ribosomal_L35Ae PF01247.18 KIK67512.1 - 9.7e-45 150.7 0.3 1.1e-44 150.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KIK67512.1 - 0.0028 17.8 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Acyl-CoA_dh_N PF02771.16 KIK67513.1 - 1.5e-27 96.5 0.0 2.8e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIK67513.1 - 3.3e-27 95.6 0.1 4.9e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK67513.1 - 1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK67513.1 - 7.7e-05 23.0 0.1 0.00032 21.0 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_B_thumb PF14791.6 KIK67514.1 - 3.1e-20 72.1 0.1 7.7e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KIK67514.1 - 1.4e-19 70.4 0.1 3.5e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KIK67514.1 - 5.6e-12 45.9 0.0 2.2e-10 40.8 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KIK67514.1 - 4e-10 39.4 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KIK67514.1 - 5.3e-07 30.2 0.0 0.00011 22.8 0.0 3.0 2 1 1 3 3 3 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KIK67514.1 - 0.00046 20.4 0.0 0.0054 16.9 0.0 2.3 2 0 0 2 2 2 1 Pathogenicity locus BRCT_2 PF16589.5 KIK67514.1 - 0.00094 19.6 0.0 0.0026 18.1 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KIK67514.1 - 0.11 12.9 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif ARTD15_N PF18084.1 KIK67514.1 - 0.14 12.4 0.2 10 6.4 0.0 2.7 2 0 0 2 2 2 0 ARTD15 N-terminal domain TP1 PF02079.16 KIK67514.1 - 0.14 12.1 0.1 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Nuclear transition protein 1 HHH_3 PF12836.7 KIK67514.1 - 0.18 12.1 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif CTP_transf_like PF01467.26 KIK67515.1 - 8.7e-25 87.6 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like MFS_1 PF07690.16 KIK67517.1 - 1.4e-31 109.8 37.9 1.4e-31 109.8 37.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK67518.1 - 1.3e-23 83.5 28.4 2.6e-22 79.2 28.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily bZIP_1 PF00170.21 KIK67519.1 - 2.7e-08 33.8 8.0 2.7e-08 33.8 8.0 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIK67519.1 - 1.6e-05 24.8 8.4 1.6e-05 24.8 8.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper ABC_tran_CTD PF16326.5 KIK67519.1 - 0.12 12.6 8.4 0.25 11.6 8.4 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain ExoD PF06055.12 KIK67519.1 - 0.32 10.3 1.0 0.52 9.7 1.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD bZIP_Maf PF03131.17 KIK67519.1 - 9.3 6.9 9.9 1.2 9.7 1.6 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor F-box-like PF12937.7 KIK67521.1 - 1.1 9.2 3.8 0.5 10.3 0.7 2.1 2 0 0 2 2 2 0 F-box-like Amidohydro_1 PF01979.20 KIK67522.1 - 1.2e-20 74.1 0.0 3.3e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIK67522.1 - 2.9e-10 40.2 0.7 8.5e-09 35.4 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Ribosomal_S19 PF00203.21 KIK67523.1 - 2.4e-26 91.4 0.0 2.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 F-box PF00646.33 KIK67524.1 - 2.8e-05 23.9 3.2 8.3e-05 22.4 0.8 2.5 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 KIK67524.1 - 9.6e-05 22.2 2.0 0.0079 16.1 2.0 2.8 1 1 0 1 1 1 1 F-box-like Choline_kin_N PF04428.14 KIK67527.1 - 0.1 12.3 0.0 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 Choline kinase N terminus DUF4253 PF14062.6 KIK67528.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Nup188_C PF18378.1 KIK67530.1 - 0.12 11.2 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Arrestin_N PF00339.29 KIK67532.1 - 0.021 14.9 0.0 1.5 8.9 0.0 3.1 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF1964 PF09244.10 KIK67532.1 - 0.22 12.0 1.2 2.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1964) Arrestin_C PF02752.22 KIK67533.1 - 0.0019 18.7 0.0 0.0021 18.5 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF4059 PF13268.6 KIK67533.1 - 0.082 13.3 1.2 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) F-box PF00646.33 KIK67534.1 - 2e-08 33.9 0.2 4.6e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK67534.1 - 5.9e-08 32.5 0.3 1.2e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like Pro_CA PF00484.19 KIK67535.1 - 3.8e-16 59.8 0.1 5e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Malic_M PF03949.15 KIK67537.1 - 1.9e-87 292.8 0.0 2.5e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIK67537.1 - 1.2e-67 227.2 0.0 1.7e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain F-box-like PF12937.7 KIK67538.1 - 2.1e-09 37.1 2.6 6.7e-09 35.5 2.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK67539.1 - 1.8e-07 30.8 0.3 1.8e-07 30.8 0.3 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK67539.1 - 8e-05 22.5 0.3 8e-05 22.5 0.3 2.6 3 0 0 3 3 3 1 F-box-like Cupredoxin_1 PF13473.6 KIK67541.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain DUF4871 PF16167.5 KIK67541.1 - 0.12 12.4 0.4 0.55 10.3 0.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4871) SSP160 PF06933.11 KIK67541.1 - 3 5.9 22.7 0.81 7.8 7.4 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Vps51 PF08700.11 KIK67542.1 - 1.6e-22 79.4 0.8 2.3e-22 78.9 0.8 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KIK67542.1 - 6.2e-05 23.2 1.7 9.3e-05 22.6 1.7 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KIK67542.1 - 0.022 13.5 1.0 0.029 13.0 1.0 1.1 1 0 0 1 1 1 0 Dor1-like family FlgN PF05130.12 KIK67542.1 - 0.053 14.0 0.5 0.072 13.6 0.5 1.2 1 0 0 1 1 1 0 FlgN protein STE3 PF02076.15 KIK67548.1 - 3.7e-99 331.6 13.4 4.2e-99 331.4 13.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF554 PF04474.12 KIK67548.1 - 0.0016 18.0 0.2 0.0027 17.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF554) DUF2518 PF10726.9 KIK67548.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of function (DUF2518) Tim17 PF02466.19 KIK67549.1 - 2.9e-31 108.1 9.2 3.9e-31 107.7 9.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4685 PF15737.5 KIK67550.1 - 0.018 15.5 0.4 0.025 15.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) Claudin_2 PF13903.6 KIK67552.1 - 0.017 14.9 6.0 1.9 8.2 4.0 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1211 PF06736.11 KIK67552.1 - 0.033 14.6 2.9 1.1 9.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) PMP22_Claudin PF00822.20 KIK67552.1 - 0.037 13.9 7.3 0.24 11.3 2.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.9 KIK67552.1 - 0.13 11.0 0.2 0.27 9.9 0.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SirB PF04247.12 KIK67552.1 - 0.13 12.3 3.6 0.73 9.9 0.7 2.3 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MgtE PF01769.16 KIK67552.1 - 0.16 12.4 3.6 3.8 7.9 2.3 2.1 2 0 0 2 2 2 0 Divalent cation transporter TctB PF07331.11 KIK67552.1 - 0.35 11.2 4.5 0.81 10.0 2.0 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4231 PF14015.6 KIK67552.1 - 2.9 8.4 8.6 1.3 9.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ribosomal_L14 PF00238.19 KIK67553.1 - 2.3e-34 118.1 0.0 2.8e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e AAA_12 PF13087.6 KIK67555.1 - 1.4e-15 57.5 0.0 3.9e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK67555.1 - 1.6e-12 47.8 0.0 5.7e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK67555.1 - 3.6e-11 43.2 0.0 8.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK67555.1 - 3.2e-08 34.0 0.0 6.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK67555.1 - 1e-05 25.3 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KIK67555.1 - 0.00066 19.2 0.0 0.5 9.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 KIK67555.1 - 0.0012 19.1 0.6 0.19 12.0 0.0 3.9 3 2 0 3 3 3 1 AAA domain DEAD PF00270.29 KIK67555.1 - 0.0036 17.1 0.0 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Cas_Cas4 PF01930.17 KIK67555.1 - 0.011 15.9 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF83 UvrD_C PF13361.6 KIK67555.1 - 0.036 13.4 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 KIK67555.1 - 0.068 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily ResIII PF04851.15 KIK67555.1 - 0.16 12.0 0.0 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KIK67555.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3944 PF13099.6 KIK67555.1 - 0.17 11.8 0.6 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) TrkH PF02386.16 KIK67556.1 - 9.8e-107 357.5 16.3 2.1e-102 343.2 9.3 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.11 KIK67556.1 - 0.48 10.4 3.2 0.27 11.2 0.2 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Ion_trans_2 PF07885.16 KIK67556.1 - 3.6 7.6 14.2 0.43 10.6 6.1 3.2 2 0 0 2 2 2 0 Ion channel MIF4G PF02854.19 KIK67557.1 - 3.1e-56 190.4 1.0 7.3e-56 189.2 1.0 1.7 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KIK67557.1 - 3.1e-18 65.7 0.0 1.3e-17 63.7 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 KIK67557.1 - 8.7e-07 28.9 0.1 3.1e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 MA3 domain PEP_mutase PF13714.6 KIK67558.1 - 2.3e-46 158.2 0.5 2.8e-46 157.9 0.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIK67558.1 - 3e-18 65.6 0.1 4.2e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family ABC_tran PF00005.27 KIK67559.1 - 6.9e-38 130.3 0.3 6.3e-17 62.4 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KIK67559.1 - 6e-16 59.1 6.6 7.2e-07 29.3 1.9 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK67559.1 - 8.6e-13 48.2 0.6 0.00076 19.0 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KIK67559.1 - 4.5e-10 39.4 2.0 4.5e-10 39.4 2.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 KIK67559.1 - 2.2e-07 30.5 0.6 0.0061 16.3 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK67559.1 - 2.6e-06 27.9 3.5 0.0065 16.9 0.0 2.8 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KIK67559.1 - 2.6e-06 28.1 6.2 0.04 14.4 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KIK67559.1 - 5.6e-06 26.2 0.0 0.046 13.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIK67559.1 - 1.3e-05 25.2 5.4 0.064 13.3 0.2 3.5 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK67559.1 - 1.5e-05 25.3 0.4 0.37 11.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KIK67559.1 - 9.2e-05 22.4 2.5 0.067 13.1 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase MeaB PF03308.16 KIK67559.1 - 9.5e-05 21.5 0.4 0.034 13.1 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KIK67559.1 - 0.00034 20.8 3.0 0.29 11.2 0.3 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain DUF815 PF05673.13 KIK67559.1 - 0.00049 19.3 0.7 0.77 8.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_14 PF13173.6 KIK67559.1 - 0.00075 19.5 0.6 0.38 10.8 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KIK67559.1 - 0.00094 19.0 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIK67559.1 - 0.0021 18.2 2.5 0.86 9.7 0.2 2.9 3 0 0 3 3 3 2 AAA domain AAA_27 PF13514.6 KIK67559.1 - 0.0022 17.6 0.1 0.53 9.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK67559.1 - 0.0022 17.9 1.9 1.2 9.0 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA PF00004.29 KIK67559.1 - 0.0031 17.9 0.0 1.1 9.7 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK67559.1 - 0.0032 18.0 0.1 3.4 8.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KIK67559.1 - 0.0035 16.6 3.2 0.58 9.3 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain Roc PF08477.13 KIK67559.1 - 0.0085 16.3 0.0 4.6 7.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KIK67559.1 - 0.0089 16.0 0.8 3.3 7.6 0.0 3.3 4 0 0 4 4 3 1 NTPase MobB PF03205.14 KIK67559.1 - 0.015 15.2 0.0 0.43 10.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 KIK67559.1 - 0.018 15.5 0.0 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KIK67559.1 - 0.027 13.8 1.4 5.8 6.2 0.2 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KIK67559.1 - 0.031 14.7 1.2 6.7 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 KIK67559.1 - 0.037 13.8 0.0 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 KIK67559.1 - 0.038 14.0 0.2 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIK67559.1 - 0.056 13.0 0.2 7.3 6.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIK67559.1 - 0.079 12.7 0.2 7 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KIK67559.1 - 0.085 12.5 0.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Thymidylate kinase ILEI PF15711.5 KIK67559.1 - 0.099 13.1 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Interleukin-like EMT inducer IstB_IS21 PF01695.17 KIK67559.1 - 0.11 12.2 0.1 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KIK67559.1 - 0.14 12.1 0.3 3.4 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KIK67559.1 - 0.17 11.5 1.9 4.4 6.9 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KIK67559.1 - 1 8.9 6.2 26 4.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain TMEM70 PF06979.12 KIK67561.1 - 0.0065 16.9 0.3 0.01 16.3 0.3 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Granulin PF00396.18 KIK67564.1 - 7.2 7.0 25.7 3.8 7.9 16.1 2.7 1 1 1 2 2 2 0 Granulin ECH_1 PF00378.20 KIK67565.1 - 3e-57 193.8 0.0 3.8e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK67565.1 - 1.9e-29 103.2 0.0 4.9e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GHMP_kinases_C PF08544.13 KIK67565.1 - 0.16 12.4 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal F-box-like PF12937.7 KIK67566.1 - 1.6e-10 40.7 10.2 1.5e-09 37.6 3.3 3.8 3 1 0 3 3 3 2 F-box-like TnsD PF15978.5 KIK67566.1 - 0.04 12.9 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D DUF1622 PF07784.11 KIK67567.1 - 0.048 13.6 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) DUF3035 PF11233.8 KIK67567.1 - 0.091 13.0 0.2 0.11 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Nop10p PF04135.12 KIK67569.1 - 0.5 10.5 3.4 0.95 9.5 0.1 2.4 1 1 1 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Foie-gras_1 PF11817.8 KIK67572.1 - 5.4e-12 45.9 0.0 2.4e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Foie gras liver health family 1 TRAPPC10 PF12584.8 KIK67572.1 - 0.0017 18.1 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KIK67572.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking CCDC117 PF15810.5 KIK67572.1 - 0.23 11.8 1.1 0.41 10.9 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 Lsr2 PF11774.8 KIK67572.1 - 1.5 9.0 4.4 4.3 7.5 0.5 2.5 2 0 0 2 2 2 0 Lsr2 Glyco_transf_22 PF03901.17 KIK67574.1 - 4.9e-42 144.6 15.8 6.1e-42 144.3 15.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Collagen PF01391.18 KIK67575.1 - 0.019 14.7 3.9 0.019 14.7 3.9 3.1 4 0 0 4 4 4 0 Collagen triple helix repeat (20 copies) Aldedh PF00171.22 KIK67577.1 - 1.6e-159 531.3 3.8 1.8e-159 531.2 3.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRM_1 PF00076.22 KIK67578.1 - 3.4e-19 68.4 0.0 1.6e-08 34.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK67578.1 - 0.0027 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KIK67578.1 - 0.054 13.3 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Remorin_N PF03766.13 KIK67578.1 - 0.056 13.5 0.6 0.056 13.5 0.6 2.6 2 0 0 2 2 2 0 Remorin, N-terminal region AIP3 PF03915.13 KIK67580.1 - 0.04 13.0 0.1 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 APH PF01636.23 KIK67581.1 - 0.044 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ART-PolyVal PF18760.1 KIK67582.1 - 0.052 14.6 0.0 0.17 12.9 0.0 1.7 1 1 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins Zn_clus PF00172.18 KIK67583.1 - 1.4e-05 25.1 5.5 2.8e-05 24.2 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1178 PF06676.11 KIK67583.1 - 0.27 11.6 1.2 0.86 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) DUF1361 PF07099.11 KIK67584.1 - 0.0015 18.5 5.6 0.13 12.2 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1361) EI24 PF07264.11 KIK67584.1 - 0.0026 18.0 1.4 0.12 12.6 1.4 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3176 PF11374.8 KIK67584.1 - 5 7.4 9.4 10 6.3 6.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3176) Ofd1_CTDD PF10637.9 KIK67585.1 - 2e-41 142.0 0.1 1.4e-39 136.0 0.1 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KIK67585.1 - 3.2e-30 104.6 0.0 5.8e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIK67585.1 - 7.2e-15 55.7 0.0 3e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 KIK67586.1 - 9.6e-23 80.8 0.1 1.5e-22 80.2 0.1 1.3 1 1 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term Pkinase_fungal PF17667.1 KIK67587.1 - 2.7e-49 168.0 0.2 5.6e-33 114.3 0.2 2.2 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK67587.1 - 0.0013 18.2 0.1 0.0035 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KIK67587.1 - 0.008 16.1 0.2 0.008 16.1 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Herpes_IE68 PF02479.16 KIK67587.1 - 0.016 14.8 0.5 0.036 13.7 0.5 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein Haspin_kinase PF12330.8 KIK67587.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-A20 PF01754.16 KIK67587.1 - 2.5 8.1 5.7 2.8 7.9 0.4 2.4 2 0 0 2 2 2 0 A20-like zinc finger Pkinase_fungal PF17667.1 KIK67588.1 - 7.1e-47 160.1 0.3 3.1e-32 111.9 0.2 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK67588.1 - 0.0018 18.2 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK67588.1 - 0.0063 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK67589.1 - 1.2e-48 165.9 0.2 2.4e-33 115.5 0.3 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK67589.1 - 0.0017 18.4 1.8 0.0018 18.3 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK67589.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAPS_reduct PF01507.19 KIK67590.1 - 4e-38 131.2 0.0 4.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonucleas_3_3 PF14622.6 KIK67591.1 - 4.9e-17 62.3 0.0 7.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK67591.1 - 8.4e-12 45.6 0.0 3.1e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KIK67591.1 - 0.00039 21.1 0.1 0.00077 20.1 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif ADH_zinc_N PF00107.26 KIK67592.1 - 7.4e-12 45.4 0.4 1.4e-11 44.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK67592.1 - 6.9e-09 35.6 0.4 2.2e-08 34.0 0.4 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK67592.1 - 0.00067 20.7 0.0 0.0013 19.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cyt-b5 PF00173.28 KIK67593.1 - 1.9e-23 82.4 0.0 2.5e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_XkdX PF09693.10 KIK67594.1 - 0.28 11.2 0.4 0.61 10.1 0.4 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Ribosomal_L31 PF01197.18 KIK67595.1 - 0.026 14.7 0.3 0.097 12.9 0.3 1.9 1 1 0 1 1 1 0 Ribosomal protein L31 DUF1634 PF07843.11 KIK67598.1 - 0.19 11.8 1.9 1.3 9.2 1.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) Pkinase_fungal PF17667.1 KIK67599.1 - 0.00013 20.9 0.0 0.018 13.8 0.0 2.3 1 1 0 1 1 1 1 Fungal protein kinase Abhydrolase_3 PF07859.13 KIK67604.1 - 6.8e-13 49.0 1.5 5.9e-08 32.8 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK67604.1 - 2.7e-11 43.3 0.0 9.5e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KIK67604.1 - 5.9e-06 25.4 0.0 0.22 10.3 0.0 3.1 3 0 0 3 3 3 2 Carboxylesterase family DLH PF01738.18 KIK67604.1 - 0.022 14.3 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIK67604.1 - 0.024 14.5 0.0 0.092 12.5 0.0 2.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 KIK67604.1 - 0.043 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KIK67604.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KIK67604.1 - 0.16 11.2 0.5 0.41 9.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KIK67604.1 - 0.18 11.4 0.0 7.3 6.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KIK67605.1 - 5e-11 42.5 0.0 1e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIK67605.1 - 1e-05 25.5 0.0 0.0078 16.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KIK67605.1 - 0.011 15.4 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIK67605.1 - 0.024 14.4 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KIK67605.1 - 0.04 13.4 2.3 2.5 7.5 0.3 2.9 3 0 0 3 3 3 0 Esterase PHB depolymerase FSH1 PF03959.13 KIK67605.1 - 0.053 13.2 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KIK67605.1 - 0.082 12.2 0.1 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIK67605.1 - 0.084 12.8 0.0 4.1 7.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 KIK67605.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein HIG_1_N PF04588.13 KIK67606.1 - 0.00011 22.4 0.1 0.00011 22.4 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region TraQ PF09679.10 KIK67606.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Nucleoporin2 PF04096.14 KIK67607.1 - 4.6e-44 150.1 0.0 9.1e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KIK67607.1 - 1.1e-11 45.4 134.8 3.4e-06 27.8 36.9 10.7 4 2 7 11 11 11 6 Nucleoporin FG repeat region RNA_pol_Rpb2_6 PF00562.28 KIK67608.1 - 2e-111 372.8 0.0 4e-111 371.8 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIK67608.1 - 6.8e-33 113.9 0.0 1.1e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KIK67608.1 - 2.6e-28 98.0 0.0 6.4e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KIK67608.1 - 1.3e-23 82.7 0.0 3.1e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KIK67608.1 - 1.1e-19 70.6 0.1 8.3e-16 58.2 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIK67608.1 - 6.7e-19 68.3 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 UnbV_ASPIC PF07593.12 KIK67608.1 - 0.13 12.3 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 ASPIC and UnbV FOXP-CC PF16159.5 KIK67611.1 - 0.00025 21.6 0.1 0.0053 17.4 0.0 2.2 2 0 0 2 2 2 1 FOXP coiled-coil domain Keratin_matx PF04579.12 KIK67612.1 - 0.99 9.8 3.8 1.2 9.5 0.2 2.5 3 0 0 3 3 3 0 Keratin, high-sulphur matrix protein E1_DerP2_DerF2 PF02221.15 KIK67613.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 ML domain Methyltransf_23 PF13489.6 KIK67615.1 - 2.4e-11 43.7 0.0 3.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK67615.1 - 3.9e-10 40.2 0.0 7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK67615.1 - 2.4e-08 34.6 0.0 5.4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK67615.1 - 4.6e-08 33.7 0.0 8.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK67615.1 - 3.8e-07 30.0 0.0 6.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK67615.1 - 0.0036 16.9 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_33 PF10017.9 KIK67615.1 - 0.023 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 KIK67615.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain C2 PF00168.30 KIK67616.1 - 6.1e-13 49.0 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain OspD PF03207.13 KIK67616.1 - 0.15 11.4 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) SMK-1 PF04802.15 KIK67617.1 - 1.2e-77 260.1 0.9 6.2e-77 257.8 0.0 2.1 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Rcd1 PF04078.13 KIK67617.1 - 7 5.8 9.0 0.33 10.2 1.6 2.4 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like MAS20 PF02064.15 KIK67618.1 - 1e-38 132.3 1.1 2.8e-38 130.9 0.1 2.2 2 0 0 2 2 2 1 MAS20 protein import receptor SET PF00856.28 KIK67618.1 - 4.9e-12 46.6 0.0 1.1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 SET domain SAF PF08666.12 KIK67618.1 - 0.013 16.1 0.1 7.5 7.3 0.0 2.6 2 0 0 2 2 2 0 SAF domain zf-MYND PF01753.18 KIK67618.1 - 0.025 14.7 0.6 0.025 14.7 0.6 2.2 2 0 0 2 2 2 0 MYND finger CopG_antitoxin PF12441.8 KIK67618.1 - 0.13 12.8 0.1 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system Abhydrolase_2 PF02230.16 KIK67619.1 - 5.2e-35 121.2 0.2 9.6e-35 120.4 0.2 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIK67619.1 - 0.06 13.9 0.0 0.073 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK67619.1 - 0.075 12.3 0.1 7.2 5.8 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIK67619.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 KIK67620.1 - 2.1e-23 82.7 0.0 3.1e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KIK67621.1 - 9.7e-48 162.8 2.5 1.3e-47 162.4 2.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK67621.1 - 2.3e-47 161.0 3.2 2.7e-47 160.8 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK67621.1 - 1.1e-08 35.2 0.4 1.6e-08 34.6 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK67621.1 - 0.014 14.9 0.2 0.028 13.9 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TcpA PF05946.12 KIK67621.1 - 0.042 14.0 0.9 0.28 11.3 0.2 2.4 2 1 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA 2-Hacid_dh_C PF02826.19 KIK67621.1 - 0.13 11.6 0.2 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA_m1G_MT PF01746.21 KIK67622.1 - 7.1e-32 110.7 0.3 1e-31 110.2 0.3 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Abhydrolase_2 PF02230.16 KIK67623.1 - 1.6e-60 204.6 0.1 2.2e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KIK67623.1 - 2.9e-07 30.0 0.5 0.042 13.1 0.2 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK67623.1 - 7.3e-05 23.5 0.4 0.00014 22.6 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KIK67623.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KIK67623.1 - 0.0039 16.7 0.0 0.36 10.3 0.0 2.2 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 KIK67623.1 - 0.0078 15.9 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KIK67623.1 - 0.0079 15.9 0.3 0.32 10.6 0.1 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIK67623.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KIK67623.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIK67623.1 - 0.021 14.3 0.0 1.4 8.3 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family IU_nuc_hydro PF01156.19 KIK67623.1 - 0.043 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase RhgB_N PF09284.10 KIK67625.1 - 2.6e-104 348.2 0.3 3.7e-104 347.7 0.3 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KIK67625.1 - 5.9e-37 127.1 0.0 1.4e-36 125.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KIK67625.1 - 7.3e-22 76.9 1.5 2.2e-21 75.4 1.5 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KIK67625.1 - 6.8e-07 29.5 5.4 1.1e-06 28.7 4.3 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KIK67625.1 - 0.037 14.0 0.2 0.08 12.9 0.2 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Adeno_shaft PF00608.17 KIK67625.1 - 0.037 13.8 0.4 0.12 12.2 0.4 1.9 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) DUF2012 PF09430.10 KIK67625.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) WCOR413 PF05562.11 KIK67627.1 - 0.046 13.7 1.4 0.089 12.7 1.4 1.4 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 DPPIV_N PF00930.21 KIK67627.1 - 0.093 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region HSP20 PF00011.21 KIK67628.1 - 4.6e-23 81.3 0.3 5.1e-23 81.2 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK67628.1 - 5.1e-10 38.8 0.0 7.6e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KIK67628.1 - 0.013 16.5 0.0 0.024 15.6 0.0 1.5 2 1 0 2 2 2 0 CS domain FKBP26_C PF18046.1 KIK67628.1 - 0.06 13.4 0.0 11 6.2 0.0 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal HSP20 PF00011.21 KIK67629.1 - 1e-21 77.0 0.2 1.3e-21 76.7 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK67629.1 - 2.9e-10 39.5 0.1 7e-10 38.3 0.1 1.7 1 1 1 2 2 2 1 HSP20-like domain found in ArsA CS PF04969.16 KIK67629.1 - 0.1 13.7 0.0 0.15 13.1 0.0 1.4 1 0 0 1 1 1 0 CS domain INTAP PF16617.5 KIK67632.1 - 0.067 13.6 0.3 0.24 11.8 0.0 1.8 1 1 1 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region PAP2 PF01569.21 KIK67632.1 - 0.077 12.8 0.1 0.085 12.6 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily Retrotran_gag_2 PF14223.6 KIK67632.1 - 0.078 12.6 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HMG_box_2 PF09011.10 KIK67633.1 - 0.09 13.4 0.5 0.22 12.1 0.5 1.7 1 0 0 1 1 1 0 HMG-box domain RNA_GG_bind PF10258.9 KIK67633.1 - 0.095 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 PHAX RNA-binding domain HTH_6 PF01418.17 KIK67634.1 - 0.08 12.9 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Csm1_N PF18504.1 KIK67636.1 - 0.0026 18.1 8.2 0.0071 16.7 0.1 3.3 2 1 2 4 4 4 1 Csm1 N-terminal domain DivIC PF04977.15 KIK67636.1 - 0.009 15.8 9.6 0.26 11.1 1.2 3.2 3 0 0 3 3 3 2 Septum formation initiator CALCOCO1 PF07888.11 KIK67636.1 - 0.025 13.5 8.4 0.033 13.1 8.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like COP23 PF14218.6 KIK67636.1 - 0.026 14.3 2.0 0.037 13.8 1.9 1.4 1 1 0 1 1 1 0 Circadian oscillating protein COP23 Baculo_PEP_C PF04513.12 KIK67636.1 - 0.076 13.1 2.6 0.17 11.9 2.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KIK67636.1 - 0.26 11.7 8.7 0.52 10.7 8.7 1.5 1 1 0 1 1 1 0 Fez1 HMMR_C PF15908.5 KIK67636.1 - 0.56 10.5 6.3 1.6 9.0 1.2 2.6 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal DUF2408 PF10303.9 KIK67636.1 - 0.94 10.0 6.4 0.65 10.6 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) MAP65_ASE1 PF03999.12 KIK67636.1 - 1.1 7.9 8.3 1.8 7.1 8.3 1.3 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GIT_CC PF16559.5 KIK67636.1 - 3.3 7.7 9.7 9.1 6.2 0.4 3.6 2 2 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 KIK67636.1 - 5.6 7.4 11.3 18 5.8 1.2 3.9 2 1 2 4 4 4 0 TSC-22/dip/bun family Adeno_E3_15_3 PF03307.14 KIK67637.1 - 0.028 14.4 0.1 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region Flavi_NS1 PF00948.21 KIK67637.1 - 0.046 12.6 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 KDZ PF18758.1 KIK67638.1 - 2.4e-37 128.7 1.6 5e-37 127.7 1.6 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK67638.1 - 2.7e-12 46.8 0.0 8.8e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases GxGYxYP_C PF14323.6 KIK67638.1 - 0.11 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Cauli_VI PF01693.16 KIK67640.1 - 0.02 15.2 0.7 0.04 14.2 0.7 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin PI3K_1B_p101 PF10486.9 KIK67640.1 - 0.068 11.0 0.9 0.11 10.3 0.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Siah-Interact_N PF09032.11 KIK67641.1 - 0.044 14.1 0.4 0.14 12.5 0.3 1.9 1 1 1 2 2 2 0 Siah interacting protein, N terminal RVT_1 PF00078.27 KIK67642.1 - 6.6e-06 25.8 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KIK67643.1 - 8.8e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RNase_H PF00075.24 KIK67644.1 - 4e-09 36.8 0.1 2.4e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 KIK67644.1 - 1.6e-05 25.6 2.0 2.5e-05 24.9 1.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Phage_min_cap2 PF06152.11 KIK67644.1 - 0.029 13.3 0.1 0.044 12.7 0.1 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 Retrotran_gag_2 PF14223.6 KIK67645.1 - 1.4e-12 47.5 0.1 2.1e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HSP20 PF00011.21 KIK67647.1 - 6.1e-24 84.1 0.4 8.5e-24 83.6 0.3 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK67647.1 - 3.9e-11 42.3 0.0 6.1e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA RRM_1 PF00076.22 KIK67648.1 - 1e-10 41.2 0.2 4e-07 29.8 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Opi1 PF08618.10 KIK67649.1 - 1.4e-24 87.2 1.8 6.3e-24 85.0 0.0 2.0 2 0 0 2 2 2 1 Transcription factor Opi1 Perilipin PF03036.16 KIK67649.1 - 0.00018 20.7 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 Perilipin family REF PF05755.12 KIK67649.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) Opi1 PF08618.10 KIK67650.1 - 1e-49 169.9 13.4 3.2e-48 165.0 13.4 2.4 1 1 0 1 1 1 1 Transcription factor Opi1 Pex14_N PF04695.13 KIK67650.1 - 5.2 7.7 10.0 3.1 8.4 3.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Opi1 PF08618.10 KIK67651.1 - 4.9e-39 134.8 8.0 7.7e-38 130.8 8.0 2.1 1 1 0 1 1 1 1 Transcription factor Opi1 PocR PF10114.9 KIK67652.1 - 0.064 13.0 0.0 0.077 12.8 0.0 1.1 1 0 0 1 1 1 0 Sensory domain found in PocR Opi1 PF08618.10 KIK67654.1 - 1.4e-38 133.3 7.9 2.2e-37 129.4 7.9 2.1 1 1 0 1 1 1 1 Transcription factor Opi1 CLPTM1 PF05602.12 KIK67655.1 - 9.8e-153 509.2 0.0 1.2e-152 509.0 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KIK67655.1 - 0.0003 20.5 0.6 0.0042 16.8 0.2 2.5 2 0 0 2 2 2 1 PQ loop repeat TMEM208_SND2 PF05620.11 KIK67655.1 - 0.13 12.0 0.9 2.4 7.9 0.1 3.3 4 0 0 4 4 4 0 SRP-independent targeting protein 2/TMEM208 2TM PF13239.6 KIK67655.1 - 1.6 9.1 8.8 0.35 11.2 1.3 3.1 3 0 0 3 3 3 0 2TM domain 14-3-3 PF00244.20 KIK67656.1 - 9.1e-108 358.9 3.3 1.1e-107 358.7 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KIK67656.1 - 0.34 11.5 2.5 0.62 10.6 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PGAP1 PF07819.13 KIK67657.1 - 1.6e-54 185.1 0.0 2.2e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIK67657.1 - 4.3e-06 27.5 0.1 4.3e-06 27.5 0.1 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK67657.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK67657.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KIK67657.1 - 0.041 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KIK67657.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Got1 PF04178.12 KIK67657.1 - 0.16 12.4 10.1 3.7 8.0 0.1 2.9 2 0 0 2 2 2 0 Got1/Sft2-like family DUF3561 PF12084.8 KIK67657.1 - 9.8 6.3 11.5 12 6.0 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) PLU-1 PF08429.11 KIK67658.1 - 1.2e-47 162.8 7.9 2.6e-47 161.7 7.9 1.7 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 KIK67658.1 - 1e-39 135.5 0.6 5e-39 133.3 0.3 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KIK67658.1 - 1.7e-20 73.5 0.0 1.3e-19 70.6 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KIK67658.1 - 1.5e-14 53.7 3.1 2.4e-14 53.0 1.9 2.1 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KIK67658.1 - 4e-13 49.5 10.4 1.4e-12 47.7 10.4 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 KIK67658.1 - 1.8e-12 46.9 21.6 1.2e-10 41.0 10.0 5.0 4 1 0 4 4 4 3 PHD-finger ubiquitin PF00240.23 KIK67659.1 - 2.8e-34 116.7 0.5 6.3e-34 115.6 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KIK67659.1 - 2.1e-26 91.8 2.1 2.1e-26 91.8 2.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KIK67659.1 - 2.5e-16 59.3 0.8 5.3e-16 58.2 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK67659.1 - 2.7e-05 24.5 0.4 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK67659.1 - 0.00043 20.4 0.6 0.00097 19.2 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK67659.1 - 0.0036 17.6 1.0 0.0065 16.8 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK67659.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KIK67659.1 - 0.013 16.1 0.8 0.018 15.6 0.8 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain IBR PF01485.21 KIK67659.1 - 0.02 15.1 0.4 0.034 14.4 0.4 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 KIK67659.1 - 0.031 14.3 1.3 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4925 PF16272.5 KIK67659.1 - 0.11 11.9 0.2 0.16 11.5 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) Pro-kuma_activ PF09286.11 KIK67660.1 - 7.5e-39 133.3 0.1 1.5e-38 132.3 0.0 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK67660.1 - 0.00015 21.2 0.1 0.00049 19.4 0.0 1.8 2 0 0 2 2 2 1 Subtilase family VIR_N PF15912.5 KIK67662.1 - 2.4e-05 24.1 0.6 0.00015 21.4 0.6 2.1 1 1 0 1 1 1 1 Virilizer, N-terminal CorA PF01544.18 KIK67663.1 - 8.5e-46 156.6 0.1 1e-45 156.3 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KIK67663.1 - 0.043 13.8 0.9 0.075 13.1 0.3 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2207 PF09972.9 KIK67663.1 - 0.055 12.2 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CopD PF05425.13 KIK67663.1 - 0.063 13.7 1.3 0.089 13.2 1.3 1.2 1 0 0 1 1 1 0 Copper resistance protein D F-box-like PF12937.7 KIK67665.1 - 8.2e-05 22.4 0.2 0.00027 20.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like Uds1 PF15456.6 KIK67666.1 - 5e-28 97.9 2.7 5e-28 97.9 2.7 6.8 4 2 1 6 6 6 2 Up-regulated During Septation DUF730 PF05325.11 KIK67666.1 - 0.19 11.7 1.0 0.94 9.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF730) zf-C2H2_4 PF13894.6 KIK67667.1 - 5.2e-05 23.7 11.4 0.021 15.7 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK67667.1 - 0.00015 21.4 2.3 0.00031 20.4 2.3 1.5 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KIK67667.1 - 0.0005 20.3 3.2 0.001 19.3 3.2 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KIK67667.1 - 0.00097 19.5 13.3 0.19 12.3 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK67667.1 - 0.011 16.0 5.4 0.1 12.9 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KIK67667.1 - 0.16 12.6 5.3 1.7 9.3 1.1 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DEC-1_C PF04626.13 KIK67667.1 - 1.4 9.3 4.4 2.6 8.5 1.6 2.1 1 1 1 2 2 2 0 Dec-1 protein, C terminal region zf-C2H2_4 PF13894.6 KIK67668.1 - 6.3e-05 23.5 4.7 0.019 15.7 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KIK67668.1 - 0.0027 17.9 2.2 0.0035 17.6 0.3 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KIK67668.1 - 0.0039 17.5 0.1 0.0039 17.5 0.1 2.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK67668.1 - 0.012 15.8 0.5 0.012 15.8 0.5 2.2 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding DAAD PF18752.1 KIK67668.1 - 0.024 14.5 0.5 0.034 14.0 0.5 1.2 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase zf-C2H2 PF00096.26 KIK67668.1 - 0.054 14.0 9.3 0.24 12.0 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KIK67668.1 - 2.3 8.0 8.7 0.13 12.0 2.7 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KIK67668.1 - 7.9 6.6 10.4 56 3.9 5.8 2.5 1 1 1 2 2 2 0 BED zinc finger RdRP PF05183.12 KIK67671.1 - 3.5e-167 557.6 0.0 4.8e-167 557.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hep_59 PF07052.11 KIK67672.1 - 5.7e-26 91.3 0.7 5.7e-26 91.3 0.7 3.1 4 0 0 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 Pro-kuma_activ PF09286.11 KIK67673.1 - 5.8e-36 123.9 0.1 9.7e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK67673.1 - 1.2e-05 24.8 0.0 2.6e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Subtilase family DUF5609 PF18429.1 KIK67673.1 - 0.11 12.2 0.1 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) PALP PF00291.25 KIK67674.1 - 1e-59 202.4 0.0 5.5e-59 200.0 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 KIK67675.1 - 3.3e-22 78.9 45.1 1.6e-18 66.8 16.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK67675.1 - 4.5e-05 22.5 11.3 4.5e-05 22.5 11.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter ATP-synt_C PF00137.21 KIK67675.1 - 7.3 7.0 11.4 0.12 12.8 2.1 2.8 2 0 0 2 2 2 0 ATP synthase subunit C CENP-T_C PF15511.6 KIK67676.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK67676.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK67676.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK67676.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK67676.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK67676.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF2009 PF09418.10 KIK67677.1 - 5.1e-213 708.2 0.0 6.2e-213 707.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KIK67677.1 - 2.2e-06 27.7 5.7 4e-06 26.9 5.7 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KIK67677.1 - 9.7e-06 25.7 4.2 1.9e-05 24.8 4.2 1.4 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 KIK67677.1 - 0.45 10.4 4.9 0.87 9.5 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) eIF3m_C_helix PF18005.1 KIK67678.1 - 3.9e-13 48.9 3.7 8.6e-13 47.7 3.7 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KIK67678.1 - 4.7e-11 43.1 0.0 2.4e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF746 PF05344.11 KIK67678.1 - 0.14 12.0 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) ArgJ PF01960.18 KIK67679.1 - 2e-143 477.7 0.0 2.3e-143 477.5 0.0 1.0 1 0 0 1 1 1 1 ArgJ family ArgJ PF01960.18 KIK67681.1 - 2.3e-63 214.2 0.1 6.7e-42 143.6 0.1 3.2 1 1 2 3 3 3 3 ArgJ family Alginate_lyase PF05426.12 KIK67684.1 - 3.1e-15 56.5 3.1 4.5e-14 52.7 3.3 2.0 1 1 0 1 1 1 1 Alginate lyase SAGA-Tad1 PF12767.7 KIK67685.1 - 0.0026 17.5 0.3 0.0051 16.6 0.3 1.5 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit MAP65_ASE1 PF03999.12 KIK67685.1 - 0.94 8.1 10.6 1.8 7.2 10.6 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RNF220 PF15926.5 KIK67686.1 - 6.6e-13 48.9 16.4 1.2e-12 48.1 12.1 3.2 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KIK67686.1 - 3.4e-09 36.4 14.7 3.4e-09 36.4 14.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK67686.1 - 2.3e-06 27.3 21.7 5.1e-05 23.0 11.4 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK67686.1 - 4.4e-05 23.4 20.7 8.6e-05 22.4 12.6 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK67686.1 - 0.00017 21.4 20.8 0.00018 21.3 14.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK67686.1 - 0.00042 20.6 26.3 0.00078 19.7 16.4 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK67686.1 - 0.0017 18.3 8.2 0.0017 18.3 8.2 4.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-Di19 PF05605.12 KIK67686.1 - 0.0035 17.6 0.7 5.4 7.4 0.1 3.5 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.12 KIK67686.1 - 0.14 11.7 0.1 0.14 11.7 0.1 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding Prok-RING_4 PF14447.6 KIK67686.1 - 0.24 11.3 20.0 0.77 9.7 11.9 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIK67686.1 - 0.59 10.0 14.6 0.098 12.5 8.4 2.6 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KIK67686.1 - 4.1 7.3 11.9 1.4 8.8 5.1 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit UbiA PF01040.18 KIK67687.1 - 5.1e-39 134.1 16.5 6.5e-39 133.7 16.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Isy1 PF06246.12 KIK67688.1 - 2.9e-93 312.1 2.2 3.9e-93 311.7 2.2 1.2 1 0 0 1 1 1 1 Isy1-like splicing family AAA_23 PF13476.6 KIK67688.1 - 0.05 14.1 0.4 0.088 13.3 0.4 1.3 1 0 0 1 1 1 0 AAA domain MSA-2c PF12238.8 KIK67688.1 - 1.1 9.2 10.2 2.7 8.0 10.2 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c Abhydrolase_3 PF07859.13 KIK67689.1 - 9.4e-61 205.3 0.0 1.1e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK67689.1 - 2.9e-11 43.0 0.4 9.5e-11 41.3 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KIK67689.1 - 1.7e-05 25.6 0.0 7.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KIK67689.1 - 3.6e-05 22.8 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KIK67689.1 - 8.4e-05 21.6 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KIK67689.1 - 0.00055 19.5 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KIK67689.1 - 0.024 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.11 KIK67689.1 - 0.17 11.7 0.1 2 8.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal STIMATE PF12400.8 KIK67690.1 - 1.7e-38 132.0 5.9 3e-38 131.2 5.9 1.4 1 0 0 1 1 1 1 STIMATE family SR-25 PF10500.9 KIK67690.1 - 9.7 5.7 16.9 15 5.1 16.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GTP1_OBG PF01018.22 KIK67691.1 - 0.28 10.8 4.5 0.38 10.3 4.5 1.3 1 1 0 1 1 1 0 GTP1/OBG IPP-2 PF04979.14 KIK67693.1 - 1e-14 55.4 5.6 2.6e-14 54.1 5.0 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) AAA PF00004.29 KIK67694.1 - 7.2e-53 178.5 0.0 8.5e-40 136.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK67694.1 - 2.6e-10 40.9 0.0 0.0019 18.6 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK67694.1 - 1.5e-09 38.3 1.1 9.2e-05 22.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KIK67694.1 - 3.9e-07 29.8 0.0 8.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIK67694.1 - 4.6e-07 30.1 0.7 5.4e-05 23.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIK67694.1 - 4.9e-07 29.8 0.1 0.0032 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIK67694.1 - 6e-07 29.7 0.0 0.031 14.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIK67694.1 - 9.6e-07 28.3 0.1 0.032 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KIK67694.1 - 1.4e-06 28.1 0.1 0.035 13.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIK67694.1 - 4.5e-06 26.7 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIK67694.1 - 1.6e-05 25.5 0.1 0.032 14.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK67694.1 - 2.8e-05 23.9 0.0 0.29 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIK67694.1 - 3.6e-05 23.3 0.2 0.011 15.1 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK67694.1 - 5.5e-05 23.5 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.26 KIK67694.1 - 5.7e-05 22.9 0.0 0.45 10.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 KIK67694.1 - 0.00018 21.1 0.1 0.058 12.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KIK67694.1 - 0.00022 20.5 0.2 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 KIK67694.1 - 0.00023 21.7 0.7 0.054 14.0 0.1 2.7 3 0 0 3 3 2 1 ABC transporter IstB_IS21 PF01695.17 KIK67694.1 - 0.00033 20.5 0.2 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 KIK67694.1 - 0.00036 20.5 3.9 0.11 12.4 0.0 3.2 4 0 0 4 4 3 2 NACHT domain ATPase PF06745.13 KIK67694.1 - 0.00052 19.4 0.1 0.03 13.7 0.1 2.6 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.6 KIK67694.1 - 0.00085 19.4 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIK67694.1 - 0.0011 18.8 0.2 0.43 10.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIK67694.1 - 0.0012 18.2 0.3 0.33 10.1 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KIK67694.1 - 0.0018 18.3 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIK67694.1 - 0.0024 17.3 0.0 2.7 7.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein CDC48_2 PF02933.17 KIK67694.1 - 0.0026 17.5 0.2 0.074 12.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_11 PF13086.6 KIK67694.1 - 0.0028 17.5 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK67694.1 - 0.0029 17.6 0.1 20 5.0 0.0 4.0 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KIK67694.1 - 0.0085 15.8 0.1 2.2 8.0 0.1 2.4 2 0 0 2 2 2 1 Cytidylate kinase CDC48_N PF02359.18 KIK67694.1 - 0.011 15.8 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.11 KIK67694.1 - 0.014 15.3 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK67694.1 - 0.015 15.6 0.8 0.97 9.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 KIK67694.1 - 0.016 15.4 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIK67694.1 - 0.019 14.1 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 KIK67694.1 - 0.02 15.0 0.0 9.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_25 PF13481.6 KIK67694.1 - 0.021 14.4 5.0 7.3 6.1 0.0 4.1 3 1 0 4 4 4 0 AAA domain TniB PF05621.11 KIK67694.1 - 0.022 14.2 0.0 0.85 9.0 0.0 2.9 2 1 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 KIK67694.1 - 0.031 13.3 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein CPT PF07931.12 KIK67694.1 - 0.033 14.0 0.1 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 KIK67694.1 - 0.037 14.2 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Zeta_toxin PF06414.12 KIK67694.1 - 0.067 12.5 0.1 7.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Vps4_C PF09336.10 KIK67694.1 - 0.12 12.4 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.6 KIK67694.1 - 0.14 12.7 0.1 26 5.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK67694.1 - 0.15 11.8 0.3 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KIK67694.1 - 0.22 11.2 0.0 25 4.5 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase BTB PF00651.31 KIK67695.1 - 0.005 17.1 0.1 0.022 15.0 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain THF_DHG_CYH PF00763.23 KIK67697.1 - 5.6e-23 81.4 0.0 8.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KIK67697.1 - 9.7e-16 57.5 0.1 5.2e-09 35.6 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ORMDL PF04061.14 KIK67699.1 - 5.5e-51 172.0 4.6 7e-51 171.6 4.6 1.1 1 0 0 1 1 1 1 ORMDL family GCP_C_terminal PF04130.13 KIK67700.1 - 1.4e-37 129.8 5.0 6.8e-37 127.6 5.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIK67700.1 - 3.3e-27 95.9 0.0 7.2e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FolB PF02152.18 KIK67700.1 - 0.18 12.4 1.1 1.6 9.3 0.4 2.4 2 0 0 2 2 2 0 Dihydroneopterin aldolase QSregVF_b PF12843.7 KIK67701.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor Btz PF09405.10 KIK67702.1 - 8.7e-09 35.7 7.9 8.7e-09 35.7 7.9 2.3 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding FAM60A PF15396.6 KIK67702.1 - 0.42 10.6 5.2 0.8 9.7 0.3 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Abhydrolase_1 PF00561.20 KIK67703.1 - 3.5e-28 99.0 0.0 1.1e-26 94.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK67703.1 - 1.1e-14 55.6 0.1 1.6e-14 55.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK67703.1 - 1.3e-09 37.7 0.0 1.1e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIK67703.1 - 1.7e-06 27.0 0.0 2.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peroxidase_2 PF01328.17 KIK67705.1 - 1.5e-29 103.9 0.0 1.6e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 WD40 PF00400.32 KIK67706.1 - 5.2e-11 42.9 10.8 0.042 14.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK67706.1 - 3.4e-08 33.7 0.0 0.0053 17.0 0.0 4.8 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK67706.1 - 0.00022 21.2 0.0 0.094 12.6 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KIK67706.1 - 0.0042 16.2 0.0 0.34 9.9 0.0 2.8 3 0 0 3 3 3 1 Coatomer WD associated region PD40 PF07676.12 KIK67706.1 - 0.11 12.5 0.1 13 5.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQ-loop PF04193.14 KIK67708.1 - 3.1e-20 71.7 12.6 1.6e-11 43.8 0.5 3.1 3 0 0 3 3 3 2 PQ loop repeat PRIMA1 PF16101.5 KIK67708.1 - 7.3 6.7 7.3 2.1e+02 1.9 7.3 2.5 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 LNS2 PF08235.13 KIK67710.1 - 1.6e-99 332.0 0.0 2.1e-99 331.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KIK67710.1 - 4.7e-38 129.3 0.0 5.1e-37 125.9 0.0 2.3 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KIK67710.1 - 2e-06 27.8 0.0 4.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain FAD_binding_3 PF01494.19 KIK67711.1 - 6.1e-22 78.3 1.6 2.8e-19 69.6 1.6 3.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK67711.1 - 2.5e-07 30.8 0.2 6.2e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK67711.1 - 1.6e-06 27.6 0.5 0.00012 21.4 0.5 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK67711.1 - 9.2e-06 25.5 0.1 5.2e-05 23.0 0.0 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK67711.1 - 2.9e-05 23.3 0.0 4.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK67711.1 - 0.00084 18.6 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KIK67711.1 - 0.0023 18.5 0.2 0.0061 17.1 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIK67711.1 - 0.0047 16.6 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 KIK67711.1 - 0.029 13.7 0.2 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIK67711.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KIK67711.1 - 0.044 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KIK67711.1 - 0.052 12.8 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK67711.1 - 0.17 10.6 0.2 0.26 10.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein TIP41 PF04176.13 KIK67713.1 - 1.4e-07 31.2 0.0 1.4e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 TIP41-like family zf-C2H2 PF00096.26 KIK67714.1 - 7.6e-10 38.7 6.0 1.4e-06 28.4 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK67714.1 - 6.1e-09 35.9 8.1 6.2e-06 26.4 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK67714.1 - 3.9e-07 30.4 6.0 0.0031 18.2 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KIK67714.1 - 1.7e-06 28.2 3.3 2.3e-06 27.8 3.3 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KIK67714.1 - 0.00019 21.4 4.8 0.062 13.3 0.5 2.4 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KIK67714.1 - 0.00023 21.4 4.9 0.16 12.4 1.3 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KIK67714.1 - 0.00024 21.3 4.2 0.1 12.9 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 KIK67714.1 - 0.0014 18.7 3.8 0.43 10.8 0.3 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger PyrI_C PF02748.15 KIK67714.1 - 0.0019 18.1 3.3 0.051 13.5 0.3 2.6 2 1 1 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 KIK67714.1 - 0.012 15.7 2.3 0.9 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-met PF12874.7 KIK67714.1 - 0.027 14.9 2.6 0.96 9.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KIK67714.1 - 0.031 14.6 1.3 0.038 14.3 1.3 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zinc_ribbon_12 PF11331.8 KIK67714.1 - 0.042 13.7 0.2 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain TBP PF00352.21 KIK67714.1 - 0.044 13.7 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) zf_ZIC PF18366.1 KIK67714.1 - 0.092 12.9 3.5 0.83 9.8 0.1 2.4 1 1 1 2 2 2 0 Zic proteins zinc finger domain C5HCH PF17982.1 KIK67714.1 - 0.15 12.3 7.1 0.28 11.4 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain zinc_ribbon_5 PF13719.6 KIK67714.1 - 0.19 11.5 3.4 7.3 6.4 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 KIK67715.1 - 2.5e-07 30.8 3.6 2.5e-06 27.6 0.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK67715.1 - 2.8e-06 27.5 6.8 0.0003 21.1 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KIK67715.1 - 0.0024 17.7 1.4 0.42 10.6 0.2 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KIK67715.1 - 0.02 15.1 0.7 6.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK67715.1 - 0.048 14.5 11.6 0.066 14.1 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KIK67715.1 - 0.049 14.0 0.3 0.14 12.6 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KIK67715.1 - 0.89 9.4 4.6 4.1 7.2 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KIK67715.1 - 0.99 10.0 6.1 2.6 8.6 6.1 1.8 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain RRN3 PF05327.11 KIK67716.1 - 1.9e-192 640.7 0.0 1.7e-191 637.6 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Complex1_LYR PF05347.15 KIK67717.1 - 4.3e-10 39.5 1.3 6.8e-10 38.8 1.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-C2H2 PF00096.26 KIK67718.1 - 5.1e-08 32.9 7.5 9.4e-05 22.7 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK67718.1 - 1.7e-07 31.3 5.7 1.4e-06 28.5 0.5 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK67718.1 - 7.2e-05 23.3 7.7 0.04 14.7 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK67718.1 - 7.2e-05 22.6 4.3 0.017 15.1 1.6 2.5 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KIK67718.1 - 0.00059 20.0 0.1 0.92 9.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KIK67718.1 - 0.015 15.7 0.2 0.019 15.3 0.2 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain DUF2180 PF09947.9 KIK67718.1 - 0.017 15.0 0.4 0.15 12.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-met PF12874.7 KIK67718.1 - 0.04 14.3 1.5 0.094 13.1 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GcpE PF04551.14 KIK67718.1 - 0.048 12.7 0.5 0.055 12.6 0.2 1.3 1 1 0 1 1 1 0 GcpE protein zf_ZIC PF18366.1 KIK67718.1 - 0.087 12.9 2.4 5.9 7.1 0.3 2.5 1 1 1 2 2 2 0 Zic proteins zinc finger domain Zn_ribbon_recom PF13408.6 KIK67718.1 - 0.19 12.3 6.1 0.38 11.3 6.1 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 KIK67718.1 - 2.2 8.1 8.8 1.1 9.1 0.9 2.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KIK67719.1 - 9.2e-09 35.3 8.8 7.8e-05 22.9 2.1 3.2 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK67719.1 - 2.9e-07 30.6 8.6 7.4e-05 23.0 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK67719.1 - 1.8e-06 28.3 6.1 0.013 16.3 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KIK67719.1 - 0.0001 22.5 2.0 0.00022 21.5 2.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KIK67719.1 - 0.0056 17.0 2.7 0.019 15.3 2.7 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIK67719.1 - 0.0093 16.2 3.8 3.3 8.1 1.8 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KIK67719.1 - 0.0098 16.0 1.2 0.46 10.6 0.2 2.3 1 1 1 2 2 2 1 Zic proteins zinc finger domain zf-AN1 PF01428.16 KIK67719.1 - 0.01 16.0 4.6 0.56 10.4 0.6 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KIK67719.1 - 0.011 15.9 1.7 4 7.6 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF2321 PF10083.9 KIK67719.1 - 0.011 15.4 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_11 PF16622.5 KIK67719.1 - 0.027 14.3 3.4 0.95 9.3 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KIK67719.1 - 0.039 14.0 6.1 0.48 10.5 0.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.14 KIK67719.1 - 0.044 13.7 2.9 4.1 7.4 0.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.7 KIK67719.1 - 0.074 13.4 5.6 1.8 8.9 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KIK67719.1 - 0.12 12.4 5.3 0.51 10.3 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KIK67719.1 - 0.25 11.3 2.2 1.9 8.5 2.4 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 KIK67719.1 - 0.38 10.6 2.5 13 5.7 0.4 2.3 1 1 1 2 2 2 0 GAGA factor FYVE PF01363.21 KIK67719.1 - 0.43 10.7 5.8 1.6 8.9 5.9 1.8 1 1 0 1 1 1 0 FYVE zinc finger DUF629 PF04780.12 KIK67719.1 - 1.1 7.7 3.2 1.5 7.3 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 KIK67720.1 - 1.1e-09 38.2 6.9 2.6e-05 24.4 2.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK67720.1 - 3e-07 30.7 6.7 0.012 16.4 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK67720.1 - 3.1e-07 30.5 9.6 7.2e-05 23.0 0.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KIK67720.1 - 1.8e-06 28.1 1.9 2.9e-06 27.5 1.9 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KIK67720.1 - 0.00028 20.8 5.7 0.29 11.2 0.5 2.4 1 1 1 2 2 2 2 BED zinc finger PyrI_C PF02748.15 KIK67720.1 - 0.0017 18.2 2.6 0.16 11.9 0.4 2.3 1 1 1 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_8 PF15909.5 KIK67720.1 - 0.0024 18.1 1.5 0.0048 17.2 1.5 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KIK67720.1 - 0.005 17.1 5.2 1.1 9.7 1.0 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KIK67720.1 - 0.0052 16.9 4.9 0.21 11.8 0.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-CHCC PF10276.9 KIK67720.1 - 0.0079 16.2 2.3 0.95 9.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger domain zf-FCS PF06467.14 KIK67720.1 - 0.0099 15.8 1.0 2.6 8.0 0.2 2.3 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 KIK67720.1 - 0.013 15.8 5.5 0.79 10.1 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KIK67720.1 - 0.014 15.5 1.4 0.5 10.5 0.2 2.3 1 1 1 2 2 2 0 Zic proteins zinc finger domain DUF2321 PF10083.9 KIK67720.1 - 0.022 14.4 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HC_2 PF13913.6 KIK67720.1 - 0.079 12.9 5.1 0.62 10.0 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 KIK67720.1 - 0.096 12.5 1.4 7.1 6.5 0.3 2.6 1 1 1 2 2 2 0 GAGA factor zf-C2H2_11 PF16622.5 KIK67720.1 - 0.11 12.3 3.9 0.93 9.3 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KIK67720.1 - 0.42 11.1 4.5 5.2 7.6 0.5 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KIK67720.1 - 0.46 10.5 5.1 0.32 11.1 1.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 KIK67720.1 - 0.47 10.6 5.9 2 8.6 5.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KIK67720.1 - 0.69 10.1 7.3 2.4 8.4 0.3 3.1 3 0 0 3 3 3 0 Zinc ribbon domain TIP41 PF04176.13 KIK67721.1 - 5.6e-45 152.9 0.0 8e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Muted PF14942.6 KIK67722.1 - 0.031 14.6 1.0 0.048 14.0 0.4 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein FTA4 PF13093.6 KIK67722.1 - 0.072 13.0 0.9 0.12 12.2 0.6 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SNAP-25 PF00835.19 KIK67722.1 - 0.075 13.4 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 SNAP-25 family DegS PF05384.11 KIK67722.1 - 0.72 9.3 4.9 0.53 9.8 0.4 2.1 1 1 1 2 2 2 0 Sensor protein DegS zf-C2H2 PF00096.26 KIK67723.1 - 3.2e-09 36.7 9.7 2.7e-05 24.4 2.5 3.5 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK67723.1 - 3.2e-07 30.5 9.6 9.6e-05 22.6 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KIK67723.1 - 3.4e-06 27.2 4.4 5.8e-06 26.5 2.0 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KIK67723.1 - 1.5e-05 25.4 13.4 0.013 16.3 0.1 3.4 4 0 0 4 4 2 2 C2H2-type zinc finger zf-BED PF02892.15 KIK67723.1 - 0.00043 20.3 6.1 0.3 11.2 2.0 2.7 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.8 KIK67723.1 - 0.00092 19.4 6.9 0.82 10.0 2.2 3.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 KIK67723.1 - 0.005 17.0 7.5 0.14 12.4 2.4 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger zf-C2H2_2 PF12756.7 KIK67723.1 - 0.014 15.8 9.3 0.24 11.8 0.3 2.6 2 1 1 3 3 2 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 KIK67723.1 - 0.015 15.2 4.3 0.43 10.5 1.1 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_8 PF15909.5 KIK67723.1 - 0.015 15.5 3.6 0.025 14.9 3.0 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon DUF2321 PF10083.9 KIK67723.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Big_1 PF02369.16 KIK67723.1 - 0.029 14.4 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) zf-FCS PF06467.14 KIK67723.1 - 0.029 14.3 2.7 2.7 8.0 0.5 2.5 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf_ZIC PF18366.1 KIK67723.1 - 0.032 14.3 1.9 0.48 10.6 0.1 2.4 2 0 0 2 2 2 0 Zic proteins zinc finger domain DUF629 PF04780.12 KIK67723.1 - 0.071 11.6 1.1 0.099 11.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 KIK67723.1 - 0.087 12.8 5.3 0.67 9.9 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KIK67723.1 - 0.2 11.8 4.0 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger domain Elf1 PF05129.13 KIK67723.1 - 0.22 11.6 2.8 0.46 10.6 2.8 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-met PF12874.7 KIK67723.1 - 0.29 11.6 5.4 48 4.5 0.0 4.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK67723.1 - 0.41 10.7 5.1 0.33 11.0 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 KIK67723.1 - 0.72 10.0 6.5 3.3 7.9 6.5 2.1 1 1 0 1 1 1 0 FYVE zinc finger GAGA PF09237.11 KIK67723.1 - 1.2 9.0 6.0 8.6 6.2 0.4 3.1 2 1 1 3 3 3 0 GAGA factor zf-C2H2_11 PF16622.5 KIK67723.1 - 1.4 8.8 8.3 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type TIP41 PF04176.13 KIK67724.1 - 2.2e-56 190.0 0.0 7.4e-55 185.1 0.0 2.1 1 1 1 2 2 2 2 TIP41-like family MFS_1 PF07690.16 KIK67726.1 - 2.3e-30 105.7 36.2 2.8e-30 105.4 36.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2162 PF09930.9 KIK67726.1 - 0.00018 21.0 6.1 0.00018 21.0 6.1 2.1 2 0 0 2 2 2 1 Predicted transporter (DUF2162) Glyco_trans_2_3 PF13632.6 KIK67728.1 - 7e-56 189.3 0.7 7e-56 189.3 0.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK67728.1 - 1.9e-06 28.0 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK67728.1 - 8.4e-06 25.7 0.0 0.023 14.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK67728.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 KIK67729.1 - 1e-16 61.0 1.7 1e-16 61.0 1.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 F-box-like PF12937.7 KIK67730.1 - 0.0016 18.3 0.0 0.0047 16.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like NADH-G_4Fe-4S_3 PF10588.9 KIK67730.1 - 0.22 11.1 0.3 0.38 10.3 0.3 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Cutinase PF01083.22 KIK67732.1 - 2.9e-46 157.7 0.4 3.3e-46 157.5 0.4 1.0 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KIK67732.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_M28 PF04389.17 KIK67733.1 - 2.1e-26 92.8 0.0 3.7e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK67733.1 - 3.9e-06 26.7 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KIK67733.1 - 0.022 14.2 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Nicastrin Abhydrolase_6 PF12697.7 KIK67735.1 - 5e-07 30.5 0.0 1.1e-06 29.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_18 PF00704.28 KIK67736.1 - 2.4e-56 191.8 2.2 3e-56 191.5 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.24 KIK67737.1 - 6.2e-78 262.7 23.2 7.1e-78 262.5 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK67737.1 - 4.8e-27 94.8 49.7 4.5e-23 81.7 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SET PF00856.28 KIK67738.1 - 4.1e-07 30.5 0.0 6.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 SET domain DIOX_N PF14226.6 KIK67739.1 - 3.3e-19 69.8 0.0 6.5e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK67739.1 - 2.2e-14 53.8 0.0 5.6e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LapA_dom PF06305.11 KIK67740.1 - 0.97 9.3 5.3 0.6 10.0 0.8 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Aminotran_5 PF00266.19 KIK67741.1 - 2.9e-12 46.2 0.0 5.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIK67741.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II FMO-like PF00743.19 KIK67742.1 - 3.4e-20 72.0 0.0 2.1e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK67742.1 - 1.3e-18 67.3 0.0 4.7e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK67742.1 - 4.7e-15 55.6 0.0 7.3e-12 45.1 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK67742.1 - 6.5e-13 48.5 0.0 2.5e-10 40.0 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK67742.1 - 9.8e-06 26.1 0.1 0.013 16.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK67742.1 - 1.2e-05 24.6 0.1 0.00017 20.8 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK67742.1 - 8.3e-05 22.7 0.1 0.4 10.9 0.0 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK67742.1 - 0.00017 21.0 0.0 0.067 12.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIK67742.1 - 0.00059 18.6 0.1 0.11 11.2 0.2 2.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 KIK67742.1 - 0.0019 17.8 0.0 6.4 6.2 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KIK67742.1 - 0.0039 16.4 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KIK67742.1 - 0.004 17.6 0.0 0.2 12.1 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIK67742.1 - 0.0044 16.2 3.1 0.071 12.2 0.9 2.4 2 1 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KIK67742.1 - 0.0046 17.0 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KIK67742.1 - 0.0048 16.0 0.1 1.9 7.4 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KIK67742.1 - 0.011 15.6 0.1 0.029 14.2 0.0 1.7 3 0 0 3 3 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK67742.1 - 0.013 14.8 0.0 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIK67742.1 - 0.016 14.5 0.0 1.2 8.3 0.4 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK67742.1 - 0.023 14.0 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 KIK67742.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KIK67742.1 - 0.12 12.0 0.2 1.8 8.2 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KIK67742.1 - 0.14 12.4 0.0 32 4.8 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain AMP-binding PF00501.28 KIK67743.1 - 2.6e-18 65.9 0.0 1.3e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF5606 PF18347.1 KIK67743.1 - 0.023 14.8 0.0 4.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5606) Methyltransf_2 PF00891.18 KIK67744.1 - 1e-22 80.5 0.0 1.1e-21 77.1 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIK67744.1 - 0.00016 21.2 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KIK67744.1 - 0.00042 20.1 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK67744.1 - 0.0014 19.2 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK67744.1 - 0.0021 17.9 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK67744.1 - 0.0033 18.1 0.0 0.0086 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK67744.1 - 0.022 15.4 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KIK67744.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Vac14_Fig4_bd PF11916.8 KIK67745.1 - 9.1e-79 263.3 7.1 1.7e-78 262.4 7.1 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KIK67745.1 - 1e-40 138.2 0.1 6.1e-37 126.1 0.0 3.5 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KIK67745.1 - 1.7e-07 30.9 0.6 0.17 12.2 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 KIK67745.1 - 1.8e-05 24.8 2.3 1.4 8.9 1.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK67745.1 - 4.7e-05 23.8 0.1 8.2 7.1 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat ParcG PF10274.9 KIK67745.1 - 0.077 13.1 0.9 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Y_phosphatase3 PF13350.6 KIK67746.1 - 2.7e-63 214.1 0.0 3e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIK67746.1 - 0.0004 20.0 0.0 0.00073 19.1 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KIK67746.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIK67746.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MCM PF00493.23 KIK67747.1 - 3.8e-105 350.0 0.6 5.6e-105 349.4 0.6 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK67747.1 - 6.3e-39 132.7 0.1 1.2e-38 131.8 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KIK67747.1 - 1.7e-27 95.7 1.0 3.9e-27 94.6 1.0 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KIK67747.1 - 4.2e-26 91.6 0.3 1.5e-25 89.8 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KIK67747.1 - 2.8e-25 88.5 1.3 2.8e-25 88.5 1.3 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KIK67747.1 - 6.3e-08 32.2 0.0 7.7e-07 28.7 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK67747.1 - 0.0015 18.4 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK67747.1 - 0.0016 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KIK67747.1 - 0.015 15.3 0.0 0.057 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SapB_1 PF05184.15 KIK67747.1 - 3.3 7.8 4.5 2.2 8.4 0.6 2.6 3 0 0 3 3 3 0 Saposin-like type B, region 1 FH2 PF02181.23 KIK67748.1 - 6.7e-84 282.1 0.1 6.7e-84 282.1 0.1 3.4 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KIK67748.1 - 1.1e-21 77.3 0.0 1.1e-21 77.3 0.0 2.7 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KIK67748.1 - 2e-15 56.9 2.5 2e-15 56.9 2.5 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF4407 PF14362.6 KIK67748.1 - 0.13 11.6 17.2 0.045 13.1 9.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SKA2 PF16740.5 KIK67748.1 - 0.24 11.2 23.6 0.027 14.2 1.4 5.7 5 1 1 6 6 6 0 Spindle and kinetochore-associated protein 2 DUF16 PF01519.16 KIK67748.1 - 0.4 11.2 19.9 0.033 14.7 2.1 5.1 3 1 2 5 5 5 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.22 KIK67748.1 - 0.44 10.8 38.3 0.1 12.8 2.4 6.5 5 1 1 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Goodbye PF17109.5 KIK67748.1 - 0.92 10.0 4.7 0.78 10.2 0.9 3.0 3 0 0 3 3 2 0 fungal STAND N-terminal Goodbye domain Allexi_40kDa PF05549.11 KIK67748.1 - 1.2 8.6 10.1 0.71 9.3 0.2 3.7 3 1 1 4 4 4 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 KIK67748.1 - 2.5 8.3 17.6 5.8 7.1 3.4 4.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 KIK67748.1 - 4.3 8.0 37.8 0.034 14.8 1.0 6.8 6 1 0 7 7 5 0 SlyX DUF1798 PF08807.10 KIK67748.1 - 8.3 6.6 8.9 4.3 7.5 0.0 3.6 3 1 1 4 4 4 0 Bacterial domain of unknown function (DUF1798) Peptidase_S28 PF05577.12 KIK67749.1 - 4.6e-50 170.7 0.1 1.5e-35 122.8 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK67749.1 - 0.00058 19.4 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 KIK67749.1 - 0.0083 14.8 0.1 0.02 13.6 0.0 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 IU_nuc_hydro PF01156.19 KIK67750.1 - 3.9e-85 286.1 0.0 4.6e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DegS PF05384.11 KIK67751.1 - 0.056 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Sensor protein DegS SRR1 PF07985.12 KIK67752.1 - 4.5e-16 58.6 0.1 6.8e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 SRR1 GEN1_C PF18380.1 KIK67753.1 - 6.4e-20 72.0 0.0 6.4e-20 72.0 0.0 3.3 4 0 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KIK67753.1 - 4.9e-18 65.3 0.0 1.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK67753.1 - 2e-06 28.2 0.0 4.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_3_C PF01915.22 KIK67754.1 - 1.4e-52 178.6 0.0 4.6e-52 176.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK67754.1 - 7.5e-47 160.2 0.0 1.2e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK67754.1 - 1.2e-24 86.2 0.0 3.9e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIK67754.1 - 1.6e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain hnRNP_Q_AcD PF18360.1 KIK67754.1 - 0.025 14.5 0.1 0.077 13.0 0.1 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain adh_short PF00106.25 KIK67756.1 - 3.6e-23 82.1 1.8 3.5e-13 49.5 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK67756.1 - 2.3e-19 69.9 0.0 1.5e-15 57.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIK67756.1 - 0.0029 17.0 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KIK67756.1 - 0.0047 16.9 1.8 0.0054 16.7 0.4 1.8 2 0 0 2 2 2 1 KR domain HATPase_c PF02518.26 KIK67756.1 - 0.13 12.7 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_pol_I_A49 PF06870.12 KIK67757.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor CAP PF00188.26 KIK67758.1 - 5.5e-19 69.3 0.9 7.3e-19 68.8 0.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Prefoldin_2 PF01920.20 KIK67759.1 - 4.8e-24 84.3 1.1 5.6e-24 84.1 1.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4407 PF14362.6 KIK67759.1 - 0.003 17.0 0.5 0.004 16.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2353 PF09789.9 KIK67759.1 - 0.0044 16.4 1.2 0.097 12.0 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) OmpH PF03938.14 KIK67759.1 - 0.0061 16.9 4.6 1.3 9.4 0.2 2.1 1 1 0 2 2 2 2 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.12 KIK67759.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.4 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Lectin_N PF03954.14 KIK67759.1 - 0.028 14.2 0.5 0.27 11.0 0.5 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Prefoldin PF02996.17 KIK67759.1 - 0.03 14.3 1.5 0.13 12.1 1.5 1.8 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KIK67759.1 - 0.035 14.2 1.9 2.5 8.2 0.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4924 PF16271.5 KIK67759.1 - 0.052 13.6 0.1 0.065 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) DUF641 PF04859.12 KIK67759.1 - 0.052 13.9 2.4 0.32 11.3 0.4 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 KIK67759.1 - 0.052 13.3 1.8 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Mod_r PF07200.13 KIK67759.1 - 0.077 13.1 3.3 0.55 10.3 0.0 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_MT_bd PF06657.13 KIK67759.1 - 0.078 13.4 1.9 1.9 9.0 0.5 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ZnuA PF01297.17 KIK67759.1 - 0.13 11.6 0.3 0.28 10.6 0.3 1.6 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Fer4 PF00037.27 KIK67760.1 - 6.4e-14 51.1 17.5 2.1e-08 33.7 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIK67760.1 - 1.4e-12 48.0 10.3 2.6e-12 47.1 10.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIK67760.1 - 7.8e-11 42.8 9.5 2e-05 25.4 0.8 2.5 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KIK67760.1 - 4.7e-09 36.2 33.0 1.1e-05 25.5 13.0 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIK67760.1 - 8.2e-09 35.5 21.2 3.4e-06 27.1 12.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIK67760.1 - 1.2e-08 35.2 3.9 0.00018 21.9 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIK67760.1 - 1.7e-08 34.5 10.5 3.1e-08 33.6 10.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIK67760.1 - 5.1e-07 29.5 17.8 0.00046 20.1 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KIK67760.1 - 1.3e-06 28.1 11.7 0.0027 17.7 1.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIK67760.1 - 7.3e-06 26.1 11.0 0.00036 20.8 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIK67760.1 - 8.8e-05 23.0 10.4 0.0091 16.5 11.9 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIK67760.1 - 0.0014 19.1 11.2 0.16 12.6 0.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KIK67760.1 - 0.052 13.8 9.0 14 5.9 9.0 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIK67760.1 - 0.26 12.3 16.3 0.4 11.7 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 KIK67760.1 - 0.45 10.8 11.5 0.71 10.1 0.4 2.7 2 1 1 3 3 3 0 c-SKI Smad4 binding domain EPF PF17181.4 KIK67760.1 - 0.77 9.8 5.6 0.54 10.3 0.6 2.4 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 KIK67760.1 - 2 9.3 14.9 1.8 9.4 1.6 2.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain HMG_box PF00505.19 KIK67764.1 - 2.2e-14 53.6 17.0 3.9e-07 30.4 4.1 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK67764.1 - 8.2e-13 48.8 13.0 4.5e-06 27.2 5.8 2.6 2 0 0 2 2 2 2 HMG-box domain Acetyltransf_10 PF13673.7 KIK67765.1 - 1.2e-11 44.6 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK67765.1 - 1.3e-06 28.7 0.0 2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK67765.1 - 7.9e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KIK67765.1 - 0.013 16.2 0.0 1.3 9.8 0.0 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.6 KIK67766.1 - 5.2e-34 116.2 4.8 6.7e-12 45.4 0.0 9.8 7 4 3 10 10 10 6 PPR repeat family PPR_3 PF13812.6 KIK67766.1 - 2.3e-32 110.8 1.4 3.4e-08 33.5 0.0 6.5 5 1 0 5 5 5 5 Pentatricopeptide repeat domain PPR PF01535.20 KIK67766.1 - 2.3e-29 99.5 5.5 0.012 15.8 0.0 15.1 17 0 0 17 17 17 7 PPR repeat PPR_1 PF12854.7 KIK67766.1 - 1.1e-11 44.2 8.3 0.0012 18.5 0.0 8.9 10 0 0 10 10 10 3 PPR repeat TPR_14 PF13428.6 KIK67766.1 - 0.0024 18.5 11.5 27 5.9 0.1 7.9 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK67766.1 - 0.96 10.0 5.0 2.5 8.7 0.1 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67766.1 - 5.4 7.4 8.2 40 4.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Velvet PF11754.8 KIK67767.1 - 3.2e-73 246.7 0.3 7.3e-73 245.6 0.3 1.5 1 1 0 1 1 1 1 Velvet factor ArfGap PF01412.18 KIK67768.1 - 8.9e-33 112.8 0.2 1.4e-32 112.2 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Carboxyl_trans PF01039.22 KIK67769.1 - 7.2e-134 447.1 0.0 9.5e-134 446.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KIK67769.1 - 0.029 13.9 0.2 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 KIK67769.1 - 0.075 12.9 0.2 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HATPase_c_3 PF13589.6 KIK67770.1 - 6.7e-11 42.2 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK67770.1 - 1.4e-05 25.6 0.0 4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KIK67771.1 - 4.4e-06 26.4 0.1 8.4e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 KIK67771.1 - 0.023 14.5 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 MutL C terminal dimerisation domain ING PF12998.7 KIK67771.1 - 0.12 12.9 0.1 0.56 10.8 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SBDS PF01172.18 KIK67772.1 - 6.4e-20 71.0 0.1 8.1e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Hydrophobin PF01185.18 KIK67773.1 - 1e-22 80.5 9.5 1.3e-22 80.2 9.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AFG1_ATPase PF03969.16 KIK67775.1 - 1e-96 324.0 0.0 1.9e-93 313.3 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KIK67775.1 - 0.00045 20.6 0.2 0.74 10.2 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KIK67775.1 - 0.0033 17.7 0.0 0.0098 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KIK67775.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 KIK67775.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK67775.1 - 0.18 11.8 0.0 0.44 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2156 PF09924.9 KIK67776.1 - 4.4e-17 62.0 0.0 6.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_1 PF00583.25 KIK67776.1 - 0.0093 16.2 0.1 0.052 13.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK67776.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 KIK67776.1 - 0.17 11.4 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Autoinducer synthase Gpr1_Fun34_YaaH PF01184.19 KIK67777.1 - 1.7e-54 184.6 15.2 2.3e-54 184.2 15.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2070 PF09843.9 KIK67777.1 - 3.7 5.7 12.8 4.5 5.4 12.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tom7 PF08038.12 KIK67778.1 - 1e-20 73.1 0.2 1.2e-20 72.9 0.2 1.0 1 0 0 1 1 1 1 TOM7 family JAB PF01398.21 KIK67779.1 - 1.2e-22 80.2 0.3 2.2e-22 79.2 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIK67779.1 - 4.9e-12 46.3 0.0 9.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.16 KIK67780.1 - 8.7e-25 87.8 0.0 1.2e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 UreF adh_short PF00106.25 KIK67783.1 - 1.7e-42 145.1 0.1 2.4e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK67783.1 - 2.2e-25 89.6 0.0 3.3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK67783.1 - 9.4e-12 45.2 0.6 1.2e-10 41.6 0.6 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK67783.1 - 0.0007 19.1 0.1 0.00096 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KIK67784.1 - 2.1e-07 30.7 2.3 1.2e-06 28.4 2.3 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK67784.1 - 8.6e-06 25.5 1.1 4.7e-05 23.1 1.1 2.1 1 1 0 1 1 1 1 F-box domain Glyco_hydro_28 PF00295.17 KIK67785.1 - 4.7e-55 186.9 18.1 4.7e-55 186.9 18.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 DUF4307 PF14155.6 KIK67785.1 - 0.085 12.7 4.1 0.23 11.3 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) ACT_7 PF13840.6 KIK67786.1 - 9.2e-18 63.8 0.0 1.2e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KIK67786.1 - 0.065 13.0 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 ACT domain Haspin_kinase PF12330.8 KIK67787.1 - 1.8e-58 198.3 0.0 4.5e-58 196.9 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain SKN1 PF03935.15 KIK67788.1 - 4.2e-194 645.6 7.1 4.8e-194 645.4 7.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TM_helix PF05552.12 KIK67788.1 - 0.085 12.8 0.8 0.15 12.0 0.8 1.4 1 0 0 1 1 1 0 Conserved TM helix UCH PF00443.29 KIK67789.1 - 1.8e-51 175.1 0.1 2.5e-51 174.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK67789.1 - 2.8e-24 86.3 0.2 7.4e-24 84.9 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KIK67789.1 - 0.019 14.4 1.9 0.074 12.5 1.9 2.0 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Zn-ribbon_8 PF09723.10 KIK67789.1 - 0.023 14.8 0.5 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Zinc ribbon domain ADD_ATRX PF17981.1 KIK67789.1 - 0.12 12.3 0.7 5.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Cysteine Rich ADD domain DZR PF12773.7 KIK67789.1 - 0.23 11.5 4.3 2.7 8.1 1.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 KIK67789.1 - 0.25 11.0 2.9 0.35 10.5 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF3549 PF12069.8 KIK67789.1 - 0.36 9.8 0.6 0.68 8.9 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) zf-H2C2_2 PF13465.6 KIK67790.1 - 5.4e-10 39.2 11.8 4.4e-05 23.7 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KIK67790.1 - 1.6e-09 37.7 18.4 0.00016 21.9 2.2 3.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK67790.1 - 3.1e-06 27.5 18.5 0.015 16.1 1.6 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KIK67790.1 - 7.8e-05 22.9 2.8 2.4 8.7 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK67790.1 - 0.00016 21.8 2.9 0.087 13.1 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KIK67790.1 - 0.0023 17.6 2.8 0.49 10.2 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIK67790.1 - 0.0042 17.0 5.8 0.21 11.6 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-HYPF PF07503.12 KIK67790.1 - 0.0057 16.4 3.8 0.24 11.2 0.1 3.4 3 0 0 3 3 3 1 HypF finger FOXP-CC PF16159.5 KIK67790.1 - 0.01 16.4 5.4 0.081 13.6 0.8 2.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KIK67790.1 - 0.056 13.6 3.1 3.8 7.6 0.1 2.9 2 1 1 3 3 3 0 Aberrant zinc-finger CHORD PF04968.12 KIK67790.1 - 0.075 13.8 6.3 1.5 9.6 0.7 2.6 1 1 2 3 3 3 0 CHORD zf-C2H2_9 PF16293.5 KIK67790.1 - 0.093 12.6 2.5 0.64 9.9 0.8 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 KIK67790.1 - 0.14 12.1 3.0 1.2 9.1 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain F-box PF00646.33 KIK67791.1 - 4.6e-07 29.6 1.3 4.6e-07 29.6 1.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK67791.1 - 5.1e-06 26.3 1.0 1.2e-05 25.0 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK67791.1 - 0.057 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KIK67794.1 - 2.9e-07 30.3 0.1 1.2e-06 28.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK67794.1 - 0.00042 20.1 0.7 0.0026 17.6 0.1 2.8 2 1 0 2 2 2 1 F-box domain DUF4349 PF14257.6 KIK67794.1 - 0.0048 16.4 0.5 0.0074 15.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Vps5 PF09325.10 KIK67794.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Sld5 PF05916.11 KIK67795.1 - 2.8e-19 69.6 0.5 4e-19 69.1 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein P21-Arc PF04062.14 KIK67797.1 - 6.1e-75 251.1 0.0 6.8e-75 250.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.11 KIK67798.1 - 4.3e-29 100.5 0.4 6.9e-29 99.8 0.4 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KIK67798.1 - 5e-28 97.4 0.0 1.2e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-ribbon_3 PF13248.6 KIK67798.1 - 0.033 13.6 0.2 0.26 10.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KIK67798.1 - 0.1 12.3 2.6 1 9.1 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ten_N PF06484.12 KIK67798.1 - 0.12 12.3 0.1 0.28 11.0 0.3 1.5 1 1 0 1 1 1 0 Teneurin Intracellular Region Iso_dh PF00180.20 KIK67799.1 - 1.9e-120 402.2 0.0 2.2e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Lactonase PF10282.9 KIK67800.1 - 6.2e-26 91.5 0.0 1.8e-25 89.9 0.0 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Alpha-amylase_C PF02806.18 KIK67801.1 - 6.4e-26 90.7 0.0 5.2e-25 87.7 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KIK67801.1 - 1.2e-19 70.5 0.0 2.9e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KIK67801.1 - 2.3e-13 50.5 0.1 2.9e-09 37.0 0.1 2.3 1 1 0 2 2 2 2 Alpha amylase, catalytic domain RP853 PF17542.2 KIK67801.1 - 0.25 10.4 0.2 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized RP853 Pex14_N PF04695.13 KIK67802.1 - 8.4e-09 36.3 0.3 8.4e-09 36.3 0.3 3.7 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M24 PF00557.24 KIK67803.1 - 2.8e-10 40.2 0.0 4.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 FMO-like PF00743.19 KIK67804.1 - 3.3e-18 65.4 0.3 4e-17 61.8 0.3 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK67804.1 - 3.1e-10 39.7 0.0 6e-09 35.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK67804.1 - 5.9e-10 39.2 0.0 1.7e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK67804.1 - 1.2e-09 37.8 0.0 8.7e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK67804.1 - 6.3e-09 35.5 2.0 5.5e-08 32.4 1.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK67804.1 - 0.00086 19.0 0.1 0.004 16.8 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK67804.1 - 0.0034 17.4 0.0 0.034 14.1 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KIK67804.1 - 0.013 14.8 0.1 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family RelE PF06296.12 KIK67804.1 - 0.015 15.4 0.0 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system Ribosomal_L28e PF01778.17 KIK67805.1 - 9.3e-40 136.0 2.5 9.3e-40 136.0 2.5 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KIK67805.1 - 5.2e-28 97.6 13.7 5.2e-28 97.6 13.7 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KIK67805.1 - 0.00017 21.1 14.3 0.00024 20.6 14.3 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KIK67805.1 - 0.096 12.4 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 KIK67805.1 - 0.41 9.2 27.5 0.56 8.7 27.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KIK67805.1 - 2.8 6.0 26.2 4 5.5 26.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIK67805.1 - 9 4.4 16.9 14 3.8 16.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Vps5 PF09325.10 KIK67806.1 - 5.3e-16 58.9 1.6 7.8e-16 58.3 1.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIK67806.1 - 1.6e-11 44.2 0.3 8e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 PX domain Sigma54_CBD PF04963.13 KIK67806.1 - 0.055 13.3 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF615 PF04751.14 KIK67806.1 - 0.12 12.3 6.3 0.043 13.8 3.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF615) Glyco_hydro_17 PF00332.18 KIK67807.1 - 8.6e-08 32.1 3.9 1.5e-06 28.0 3.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GTP_cyclohydro2 PF00925.20 KIK67808.1 - 3.9e-59 198.9 0.0 6.3e-59 198.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF5375 PF17345.2 KIK67808.1 - 0.12 12.2 0.1 0.68 9.9 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5375) DUF3845 PF12956.7 KIK67809.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure HALZ PF02183.18 KIK67810.1 - 0.0004 20.6 4.4 1.1 9.6 0.0 3.3 3 0 0 3 3 3 2 Homeobox associated leucine zipper APC_N_CC PF16689.5 KIK67810.1 - 0.00077 19.5 0.8 0.012 15.6 0.2 2.5 2 0 0 2 2 2 1 Coiled-coil N-terminus of APC, dimerisation domain DUF4515 PF14988.6 KIK67810.1 - 0.0094 15.8 2.7 0.1 12.4 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) GAS PF13851.6 KIK67810.1 - 0.021 14.2 2.8 0.029 13.7 2.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KIK67810.1 - 0.021 15.4 1.0 0.027 15.0 1.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Taxilin PF09728.9 KIK67810.1 - 0.024 13.8 2.4 0.031 13.5 2.4 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ZapB PF06005.12 KIK67810.1 - 0.096 13.1 5.9 7.9 7.0 5.9 2.2 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KIK67810.1 - 0.12 12.1 5.6 2.8 7.8 1.7 2.7 1 1 2 3 3 3 0 Septum formation initiator Herpes_BLRF2 PF05812.12 KIK67810.1 - 0.15 12.2 4.8 0.3 11.2 0.8 2.6 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein KLRAQ PF10205.9 KIK67810.1 - 0.19 12.0 3.4 0.37 11.1 3.4 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.21 KIK67810.1 - 0.44 10.7 6.9 6.6 6.9 0.7 3.0 1 1 3 4 4 4 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 KIK67810.1 - 3 8.0 10.0 35 4.6 7.2 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 NYD-SP28_assoc PF14775.6 KIK67810.1 - 3.9 7.7 6.6 21 5.3 0.3 3.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain Cwf_Cwc_15 PF04889.12 KIK67811.1 - 0.16 11.6 6.0 0.3 10.8 6.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4964 PF16334.5 KIK67811.1 - 0.22 11.1 0.7 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) FAM176 PF14851.6 KIK67811.1 - 0.51 10.0 3.6 1 9.0 3.6 1.5 1 0 0 1 1 1 0 FAM176 family DUF3245 PF11595.8 KIK67811.1 - 0.92 10.0 9.2 2.9 8.3 9.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.6 KIK67811.1 - 1.4 9.3 5.7 4.2 7.8 5.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paramyxo_P_V_N PF13825.6 KIK67811.1 - 2.4 7.5 13.0 1.4 8.3 0.7 2.5 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus CDC45 PF02724.14 KIK67811.1 - 2.5 6.3 4.6 3.8 5.7 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.25 KIK67812.1 - 3.5e-37 127.8 0.0 5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK67812.1 - 5.5e-32 111.2 0.0 4.1e-31 108.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK67812.1 - 1.5e-06 28.3 1.5 4.4e-06 26.7 0.1 2.3 4 0 0 4 4 4 1 KR domain adh_short PF00106.25 KIK67814.1 - 6.9e-38 130.1 0.1 1.1e-37 129.3 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK67814.1 - 2.5e-33 115.6 0.0 2.7e-32 112.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK67814.1 - 1.9e-07 31.2 0.5 5.8e-07 29.6 0.1 2.0 3 0 0 3 3 3 1 KR domain Glu_dehyd_C PF16912.5 KIK67814.1 - 0.025 14.1 0.1 0.054 13.0 0.1 1.6 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 KIK67814.1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIK67814.1 - 0.14 12.0 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MelC1 PF06236.11 KIK67814.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 GDP_Man_Dehyd PF16363.5 KIK67814.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_3 PF01494.19 KIK67815.1 - 2.1e-72 244.3 0.0 2.9e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK67815.1 - 0.00022 20.6 0.1 0.035 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK67815.1 - 0.0031 17.2 0.4 0.38 10.3 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK67815.1 - 0.0036 17.5 0.1 0.0087 16.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK67815.1 - 0.0042 16.2 0.5 0.0082 15.3 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK67815.1 - 0.017 13.8 0.3 0.13 10.9 0.4 1.9 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KIK67815.1 - 0.068 13.4 0.2 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 KIK67815.1 - 0.089 13.4 0.4 6.6 7.4 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIK67815.1 - 0.098 12.3 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIK67815.1 - 0.41 9.9 0.8 1 8.6 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 KIK67816.1 - 1.8e-42 145.8 0.0 5.3e-42 144.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIK67816.1 - 0.00014 21.6 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase adh_short PF00106.25 KIK67817.1 - 2.9e-43 147.6 0.1 3.6e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK67817.1 - 5e-30 104.8 0.1 6.4e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK67817.1 - 5.2e-10 39.5 0.0 6.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK67817.1 - 8.1e-10 38.5 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK67817.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KIK67817.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Snf7 PF03357.21 KIK67818.1 - 7.8e-40 136.3 18.4 3.1e-39 134.4 13.3 2.0 2 0 0 2 2 2 1 Snf7 NPV_P10 PF05531.12 KIK67818.1 - 0.0002 21.8 2.4 0.06 13.8 0.3 2.6 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KIK67818.1 - 0.0024 18.2 5.0 0.37 11.2 0.0 3.4 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Ca_bind_SSO6904 PF18249.1 KIK67818.1 - 0.0083 16.5 0.1 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 Calcium binding protein SSO6904 GP24_25 PF17388.2 KIK67818.1 - 0.011 15.7 0.2 0.037 14.0 0.2 1.8 1 1 0 1 1 1 0 Tail assembly gene products 24 & 25 DUF5344 PF17279.2 KIK67818.1 - 0.016 15.8 9.8 0.45 11.1 5.2 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5344) DUF150 PF02576.17 KIK67818.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RimP N-terminal domain TBPIP PF07106.13 KIK67818.1 - 0.066 13.2 1.6 1 9.3 0.3 2.7 1 1 1 2 2 2 0 TBPIP/Hop2 winged helix domain bZIP_1 PF00170.21 KIK67818.1 - 0.087 12.9 10.9 0.19 11.8 0.1 4.0 2 1 1 3 3 3 0 bZIP transcription factor SelB-wing_2 PF09106.11 KIK67818.1 - 0.12 12.6 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF948 PF06103.11 KIK67818.1 - 0.18 12.1 2.8 0.54 10.5 0.8 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 KIK67818.1 - 0.58 9.0 3.0 0.68 8.8 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Uds1 PF15456.6 KIK67818.1 - 2.2 8.5 10.6 2.6e+02 1.7 10.7 2.7 1 1 0 1 1 1 0 Up-regulated During Septation Uso1_p115_C PF04871.13 KIK67818.1 - 2.7 8.4 16.2 2.8 8.3 9.5 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SOAR PF16533.5 KIK67818.1 - 6.4 6.8 8.6 16 5.6 4.9 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region SlyX PF04102.12 KIK67818.1 - 7.5 7.3 9.7 1.3e+02 3.3 0.5 3.6 1 1 1 2 2 2 0 SlyX Aldedh PF00171.22 KIK67819.1 - 1.1e-146 489.0 0.1 1.3e-146 488.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK67819.1 - 0.00017 20.8 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) RCC1 PF00415.18 KIK67820.1 - 5.4e-44 148.6 11.9 4.6e-10 40.0 0.2 7.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK67820.1 - 3.9e-34 115.8 27.1 1.1e-08 34.6 1.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KIK67820.1 - 0.0049 16.6 0.0 2.8 7.6 0.0 2.4 3 0 0 3 3 3 2 TUP1-like enhancer of split Calx-beta PF03160.14 KIK67820.1 - 0.03 14.5 0.1 8 6.7 0.0 3.1 3 0 0 3 3 3 0 Calx-beta domain Reg_prop PF07494.11 KIK67820.1 - 0.032 14.4 0.3 20 5.9 0.0 3.1 3 0 0 3 3 3 0 Two component regulator propeller DUF3659 PF12396.8 KIK67820.1 - 0.1 12.5 3.0 3.6 7.6 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) SUKH-3 PF14433.6 KIK67820.1 - 0.13 12.7 0.6 22 5.5 0.0 3.5 4 0 0 4 4 4 0 SUKH-3 immunity protein DIOX_N PF14226.6 KIK67822.1 - 5.7e-29 101.3 0.2 9e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK67822.1 - 1.1e-16 61.2 0.0 2.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4112 PF13430.6 KIK67823.1 - 4.5e-34 116.9 0.1 6e-34 116.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF3602 PF12223.8 KIK67824.1 - 8.9e-15 55.1 22.4 6.7e-06 26.6 1.3 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Dsh_C PF12316.8 KIK67824.1 - 0.091 13.2 5.2 0.14 12.6 5.2 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal BTB PF00651.31 KIK67825.1 - 2.7e-07 30.8 0.0 1.5e-06 28.4 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF3342 PF11822.8 KIK67825.1 - 0.043 14.0 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF5102 PF17104.5 KIK67826.1 - 4e-73 247.0 0.8 5.1e-73 246.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) KAR9 PF08580.10 KIK67826.1 - 0.029 12.9 3.5 0.038 12.6 3.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF3288 PF11691.8 KIK67826.1 - 0.11 12.6 0.5 0.81 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) CorA PF01544.18 KIK67826.1 - 0.16 11.3 1.0 0.28 10.5 1.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GAT PF03127.14 KIK67826.1 - 0.95 9.8 3.8 0.76 10.1 0.3 2.4 2 1 0 2 2 2 0 GAT domain RNA_pol_I_TF PF04090.12 KIK67827.1 - 6.5e-07 29.0 3.0 1.8e-05 24.4 0.7 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor Wzy_C_2 PF11846.8 KIK67827.1 - 0.043 13.7 0.0 0.075 13.0 0.0 1.5 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Spermine_synth PF01564.17 KIK67828.1 - 3.4e-11 42.9 0.0 1.3e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KIK67828.1 - 0.05 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KIK67828.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PIG-H PF10181.9 KIK67828.1 - 0.086 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component URO-D PF01208.17 KIK67828.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Peptidase_C14 PF00656.22 KIK67829.1 - 3.4e-53 181.1 0.0 4.6e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RNA_pol_Rpb1_5 PF04998.17 KIK67830.1 - 3.5e-87 292.2 0.0 7e-87 291.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIK67830.1 - 4.8e-63 212.3 0.1 8.5e-63 211.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIK67830.1 - 3.1e-35 121.4 0.0 7.5e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KIK67830.1 - 6.4e-30 104.5 2.6 5.7e-23 81.7 0.0 3.4 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KIK67830.1 - 2e-20 72.7 0.1 5.8e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PBP PF01161.20 KIK67834.1 - 1.8e-10 41.2 0.1 2.6e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RRM_1 PF00076.22 KIK67835.1 - 5.1e-19 67.9 0.1 7.6e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK67835.1 - 1.8e-08 34.0 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KIK67835.1 - 0.059 13.6 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain RRM_3 PF08777.11 KIK67835.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DEAD PF00270.29 KIK67836.1 - 2.9e-43 147.7 0.2 5.3e-43 146.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK67836.1 - 4.9e-33 113.8 0.1 2.1e-32 111.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK67836.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK67836.1 - 0.00097 19.5 0.1 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK67836.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK67836.1 - 0.038 14.3 0.5 0.23 11.7 0.5 2.1 1 1 0 1 1 1 0 AAA domain DUF1871 PF08958.10 KIK67836.1 - 0.059 13.7 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) UvrD-helicase PF00580.21 KIK67836.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3449 PF11931.8 KIK67837.1 - 4.2e-74 248.3 1.9 1.2e-73 246.9 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KIK67837.1 - 1.1e-23 83.5 1.7 1.1e-23 83.5 1.7 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KIK67837.1 - 4e-09 36.2 0.1 7.6e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KIK67837.1 - 1.3e-07 31.8 7.3 1.3e-05 25.4 2.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK67837.1 - 3.5e-07 30.3 6.9 5.6e-07 29.7 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIK67837.1 - 0.00045 20.5 0.2 0.036 14.4 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KIK67837.1 - 0.0098 16.0 2.5 0.77 9.9 0.1 2.9 2 0 0 2 2 2 1 DBF zinc finger Sod_Fe_N PF00081.22 KIK67837.1 - 0.1 13.1 0.1 0.1 13.1 0.1 2.4 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-C2H2_4 PF13894.6 KIK67837.1 - 0.17 12.8 2.6 23 6.2 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Laps PF10169.9 KIK67837.1 - 2.9 8.5 7.0 0.27 11.8 0.4 2.5 3 0 0 3 3 3 0 Learning-associated protein Syja_N PF02383.18 KIK67838.1 - 1.1e-74 251.7 0.0 1.6e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain RGCC PF15151.6 KIK67838.1 - 0.31 11.3 3.1 0.71 10.1 3.1 1.5 1 0 0 1 1 1 0 Response gene to complement 32 protein family ABC_membrane PF00664.23 KIK67839.1 - 2.1e-57 194.8 32.1 3.5e-30 105.6 20.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK67839.1 - 3e-50 170.3 0.1 2.1e-29 102.8 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK67839.1 - 8.4e-10 38.4 4.2 9.9e-05 21.9 2.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIK67839.1 - 6e-06 26.3 2.1 0.028 14.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK67839.1 - 6.1e-06 25.9 0.2 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK67839.1 - 1.4e-05 25.1 6.7 0.21 11.3 0.3 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK67839.1 - 9.8e-05 22.9 0.1 0.21 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIK67839.1 - 0.00011 22.1 2.0 0.27 11.1 0.1 2.7 3 0 0 3 3 3 2 RsgA GTPase DUF87 PF01935.17 KIK67839.1 - 0.0017 18.5 1.2 0.35 10.9 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KIK67839.1 - 0.0018 18.7 1.0 0.19 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 KIK67839.1 - 0.011 15.5 0.5 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK67839.1 - 0.027 13.4 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 KIK67839.1 - 0.028 13.6 0.8 0.42 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KIK67839.1 - 0.047 13.0 1.3 3.7 6.8 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KIK67839.1 - 0.047 13.4 4.2 0.071 12.8 0.4 2.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK67839.1 - 0.048 13.9 3.1 5.3 7.3 0.3 3.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIK67839.1 - 0.049 13.2 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KIK67839.1 - 0.065 13.3 3.4 3.3 7.7 0.8 2.5 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KIK67839.1 - 0.065 13.4 1.8 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KIK67839.1 - 0.14 11.7 0.0 19 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 KIK67839.1 - 0.26 10.6 3.2 0.83 8.9 0.1 2.7 3 0 0 3 3 3 0 AIG1 family NACHT PF05729.12 KIK67839.1 - 0.31 10.9 2.4 1 9.3 0.2 2.5 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 KIK67839.1 - 0.32 10.1 0.9 12 5.0 0.1 2.6 3 1 0 3 3 3 0 NB-ARC domain IucA_IucC PF04183.12 KIK67840.1 - 7.3e-23 81.4 0.4 7.3e-22 78.1 0.4 2.1 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 KIK67840.1 - 1.1e-10 42.1 0.0 3.3e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Snf7 PF03357.21 KIK67842.1 - 3.3e-12 46.4 14.7 4.3e-12 46.0 14.7 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KIK67842.1 - 0.0022 17.9 5.2 0.0032 17.4 5.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KIK67842.1 - 0.0077 15.9 0.6 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase IML1 PF12257.8 KIK67842.1 - 0.058 12.5 2.4 0.077 12.1 2.4 1.3 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 SlyX PF04102.12 KIK67842.1 - 8.6 7.1 8.6 1.8 9.3 0.5 3.1 4 0 0 4 4 4 0 SlyX Erv26 PF04148.13 KIK67843.1 - 1.1e-56 192.0 4.5 1.2e-56 191.8 4.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Spc7 PF08317.11 KIK67844.1 - 3.9e-05 22.7 41.0 0.00019 20.4 17.7 3.0 1 1 2 3 3 3 2 Spc7 kinetochore protein ATG16 PF08614.11 KIK67844.1 - 0.00019 21.7 37.5 0.0015 18.8 2.1 4.0 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KIK67844.1 - 0.00038 20.5 20.3 0.00038 20.5 20.3 3.8 4 1 1 5 5 4 2 TPR/MLP1/MLP2-like protein LXG PF04740.12 KIK67844.1 - 0.00085 19.1 7.1 0.00085 19.1 7.1 2.2 2 0 0 2 2 2 1 LXG domain of WXG superfamily DUF3138 PF11336.8 KIK67844.1 - 0.0014 17.3 2.3 0.022 13.4 3.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3138) TSC22 PF01166.18 KIK67844.1 - 0.0044 17.3 0.4 0.0044 17.3 0.4 4.8 4 0 0 4 4 4 1 TSC-22/dip/bun family Troponin PF00992.20 KIK67844.1 - 0.0058 16.9 15.4 0.065 13.5 0.1 3.2 3 1 1 4 4 3 2 Troponin Fib_alpha PF08702.10 KIK67844.1 - 0.017 15.3 20.5 0.18 11.9 7.2 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SesA PF17107.5 KIK67844.1 - 0.05 13.8 4.2 0.21 11.8 3.7 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4472 PF14739.6 KIK67844.1 - 0.13 13.0 19.7 0.8 10.5 5.9 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF4200 PF13863.6 KIK67844.1 - 0.18 12.2 26.2 0.057 13.8 8.9 3.6 3 1 2 5 5 4 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 KIK67844.1 - 0.2 11.7 37.5 0.36 10.8 11.4 3.2 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KIK67844.1 - 0.21 11.4 32.5 0.4 10.4 29.1 2.6 2 1 0 2 2 1 0 Ezrin/radixin/moesin family DUF1043 PF06295.12 KIK67844.1 - 0.25 11.4 5.8 0.91 9.5 5.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TBCA PF02970.16 KIK67844.1 - 0.49 10.8 17.4 3.4 8.1 1.0 4.7 2 1 2 5 5 5 0 Tubulin binding cofactor A HOOK PF05622.12 KIK67844.1 - 0.5 8.5 25.9 2 6.4 7.3 2.4 1 1 1 2 2 2 0 HOOK protein Exonuc_VII_S PF02609.16 KIK67844.1 - 0.59 10.2 11.4 0.062 13.4 2.9 3.1 1 1 2 3 3 3 0 Exonuclease VII small subunit PMEI PF04043.15 KIK67844.1 - 0.71 10.2 8.6 0.75 10.1 7.3 1.8 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF3584 PF12128.8 KIK67844.1 - 0.72 7.3 25.9 0.6 7.6 23.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Jnk-SapK_ap_N PF09744.9 KIK67844.1 - 0.85 9.8 39.9 0.29 11.3 5.9 3.9 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 KIK67844.1 - 1.4 8.4 32.1 0.32 10.4 10.6 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF724 PF05266.14 KIK67844.1 - 1.4 8.7 20.4 0.16 11.8 11.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 KIK67844.1 - 1.7 7.2 16.2 4.5 5.8 15.4 1.9 1 1 0 1 1 1 0 AAA domain APG6_N PF17675.1 KIK67844.1 - 2.7 8.5 32.6 0.13 12.8 9.7 3.4 2 1 1 3 3 2 0 Apg6 coiled-coil region FliD_N PF02465.18 KIK67844.1 - 3.1 8.5 11.7 26 5.6 7.9 3.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NPV_P10 PF05531.12 KIK67844.1 - 3.2 8.3 19.3 2.4 8.7 4.2 5.1 2 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 KIK67844.1 - 3.6 7.8 30.2 1.1 9.4 16.7 3.4 3 1 0 3 3 3 0 Tropomyosin like ZapB PF06005.12 KIK67844.1 - 3.9 8.0 32.2 0.95 9.9 1.7 4.8 3 1 1 5 5 5 0 Cell division protein ZapB MscS_porin PF12795.7 KIK67844.1 - 3.9 7.0 43.0 0.031 13.8 30.3 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain HAP1_N PF04849.13 KIK67844.1 - 4.2 6.5 28.7 1.3 8.1 8.1 2.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Lge1 PF11488.8 KIK67844.1 - 6.1 7.1 10.2 3.4 7.9 2.1 3.6 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Fez1 PF06818.15 KIK67844.1 - 6.1 7.2 30.9 1.2 9.5 12.4 3.0 2 1 1 3 3 3 0 Fez1 DUF2203 PF09969.9 KIK67844.1 - 7.1 7.4 12.7 4.7 8.0 4.2 3.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) HsbA PF12296.8 KIK67846.1 - 5.1e-17 62.4 9.2 1.4e-12 48.1 0.3 2.9 2 1 0 2 2 2 2 Hydrophobic surface binding protein A HemX PF04375.14 KIK67846.1 - 0.061 12.6 0.3 0.081 12.2 0.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Baculo_PEP_C PF04513.12 KIK67846.1 - 0.093 12.8 3.4 0.23 11.5 0.2 2.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HN PF00423.19 KIK67846.1 - 0.21 10.3 0.1 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase HsbA PF12296.8 KIK67847.1 - 1.8e-27 96.1 9.2 1.8e-27 96.1 9.2 2.0 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Filo_VP35 PF02097.15 KIK67847.1 - 0.018 14.1 0.1 2.2 7.2 0.0 2.4 2 1 1 3 3 3 0 Filoviridae VP35 Baculo_PEP_C PF04513.12 KIK67847.1 - 0.24 11.5 8.9 0.21 11.6 1.0 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HERV-K_REC PF15695.5 KIK67847.1 - 1.6 8.9 4.6 1.7 8.7 0.5 2.3 2 0 0 2 2 2 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Cupin_1 PF00190.22 KIK67848.1 - 7.3e-41 139.3 0.2 2.7e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KIK67848.1 - 9.2e-31 105.4 0.2 4.2e-15 55.2 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KIK67848.1 - 7.8e-11 41.5 0.0 0.00042 20.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KIK67848.1 - 3.1e-07 30.4 0.1 8.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KIK67848.1 - 4.9e-06 26.5 0.0 0.00043 20.2 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 KIK67848.1 - 1.3e-05 25.5 0.0 0.003 17.7 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family 3-HAO PF06052.12 KIK67848.1 - 2.3e-05 24.1 0.0 0.0032 17.1 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase cNMP_binding PF00027.29 KIK67848.1 - 0.0088 16.1 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_4 PF08007.12 KIK67848.1 - 0.017 14.6 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_8 PF13621.6 KIK67848.1 - 0.023 14.4 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Cupin-like domain Ectoine_synth PF06339.12 KIK67848.1 - 0.045 13.9 0.0 9.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Ectoine synthase Cupin_7 PF12973.7 KIK67848.1 - 0.051 13.5 0.1 12 5.9 0.0 2.7 2 1 0 2 2 2 0 ChrR Cupin-like domain EutQ PF06249.12 KIK67848.1 - 0.099 12.4 0.0 0.86 9.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ DUF2291 PF10054.9 KIK67848.1 - 0.14 11.8 0.0 2 8.1 0.0 2.1 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF4449 PF14613.6 KIK67849.1 - 2.2e-34 119.0 0.4 2.2e-34 119.0 0.4 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) Dehydrin PF00257.19 KIK67849.1 - 0.98 9.9 7.0 1.1 9.7 2.5 2.6 2 0 0 2 2 2 0 Dehydrin HABP4_PAI-RBP1 PF04774.15 KIK67850.1 - 4.4e-05 24.3 6.1 6.2e-05 23.8 6.1 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family 4HBT_2 PF13279.6 KIK67851.1 - 9.7e-10 39.0 0.0 2e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily HABP4_PAI-RBP1 PF04774.15 KIK67852.1 - 3.5e-06 27.8 2.0 4.7e-06 27.4 2.0 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Cu-oxidase PF00394.22 KIK67853.1 - 3.7e-39 134.4 4.0 5.1e-39 133.9 0.5 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK67853.1 - 1.3e-32 112.4 1.7 1e-31 109.5 0.5 2.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK67853.1 - 8.8e-30 103.2 1.7 4.6e-27 94.4 0.0 3.4 3 0 0 3 3 3 2 Multicopper oxidase MFS_1 PF07690.16 KIK67855.1 - 2.2e-42 145.2 29.0 2.2e-42 145.2 29.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK67855.1 - 1e-09 37.8 6.2 1e-09 37.8 6.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK67855.1 - 0.99 7.7 10.7 0.0073 14.8 1.8 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HMGL-like PF00682.19 KIK67857.1 - 3.6e-62 210.3 0.0 6.1e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIK67857.1 - 0.00025 20.9 0.1 0.00055 19.8 0.1 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Glyco_hydro_1 PF00232.18 KIK67858.1 - 2.1e-151 504.4 0.0 2.4e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mersacidin PF16934.5 KIK67858.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) GFO_IDH_MocA PF01408.22 KIK67859.1 - 5.5e-13 49.8 0.0 1.2e-12 48.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK67859.1 - 7.9e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DnaJ_CXXCXGXG PF00684.19 KIK67861.1 - 0.01 16.2 7.0 0.68 10.3 1.0 2.5 2 0 0 2 2 2 0 DnaJ central domain OrfB_Zn_ribbon PF07282.11 KIK67861.1 - 1.9 8.5 4.1 1.6 8.7 0.6 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Pkinase PF00069.25 KIK67862.1 - 1.4e-47 162.3 0.0 5.1e-40 137.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67862.1 - 3.4e-45 154.4 0.0 1.2e-39 136.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK67862.1 - 0.0024 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KIK67862.1 - 0.0097 15.0 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KIK67862.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyl-CoA_ox_N PF14749.6 KIK67862.1 - 0.017 15.7 0.0 0.041 14.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal SOGA PF11365.8 KIK67862.1 - 0.076 14.1 0.2 0.14 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein SOGA WaaY PF06176.11 KIK67862.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KIK67862.1 - 0.1 12.2 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family SH3_9 PF14604.6 KIK67864.1 - 1.4e-08 34.4 0.1 2.5e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK67864.1 - 1.6e-08 34.0 0.0 2.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK67864.1 - 6.1e-07 29.0 0.1 1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Aminotran_5 PF00266.19 KIK67867.1 - 8.3e-42 143.5 0.0 1.1e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cu-oxidase PF00394.22 KIK67868.1 - 1.9e-46 158.1 1.5 1.3e-44 152.1 0.2 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK67868.1 - 1.7e-40 137.9 0.6 1.9e-36 124.8 0.0 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK67868.1 - 3.2e-35 120.7 1.1 1e-32 112.7 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase PPC PF04151.15 KIK67868.1 - 0.23 12.6 4.4 0.94 10.6 0.1 3.7 3 1 1 4 4 4 0 Bacterial pre-peptidase C-terminal domain Borrelia_P83 PF05262.11 KIK67869.1 - 0.00018 20.2 4.0 0.00024 19.7 4.0 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein 4HBT PF03061.22 KIK67871.1 - 0.0006 20.1 0.1 0.0013 19.0 0.1 1.6 1 1 0 1 1 1 1 Thioesterase superfamily DUF4400 PF14348.6 KIK67871.1 - 0.026 14.0 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) 4HBT PF03061.22 KIK67872.1 - 3.1e-09 37.1 0.3 5.1e-09 36.4 0.3 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KIK67872.1 - 0.005 17.1 0.0 0.0058 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acetyltransf_1 PF00583.25 KIK67873.1 - 3.5e-13 49.8 0.0 4.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK67873.1 - 7.5e-08 32.4 0.0 9.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK67873.1 - 1.7e-07 31.5 0.0 2.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK67873.1 - 2e-05 24.5 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KIK67873.1 - 0.009 15.5 0.2 0.01 15.3 0.2 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KIK67873.1 - 0.029 14.4 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK67873.1 - 0.038 14.0 0.3 0.085 12.8 0.3 1.6 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase CENP-S PF15630.6 KIK67873.1 - 0.14 12.5 0.1 0.27 11.6 0.0 1.4 2 0 0 2 2 2 0 CENP-S protein DUF2235 PF09994.9 KIK67875.1 - 7.5e-95 317.6 0.0 1.3e-94 316.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KIK67875.1 - 0.0016 18.4 0.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2235 PF09994.9 KIK67876.1 - 6.1e-97 324.4 0.3 7.8e-97 324.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HMG_box PF00505.19 KIK67877.1 - 4.8e-10 39.7 8.9 1.5e-09 38.1 8.9 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK67877.1 - 1.8e-05 25.2 3.8 3.9e-05 24.2 3.8 1.5 1 0 0 1 1 1 1 HMG-box domain Aldedh PF00171.22 KIK67878.1 - 1.3e-121 406.4 0.1 1.6e-121 406.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M28 PF04389.17 KIK67879.1 - 5.2e-34 117.7 0.1 1e-33 116.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK67879.1 - 0.024 14.3 0.0 0.063 13.0 0.0 1.9 2 1 0 2 2 2 0 Peptidase family M20/M25/M40 DUF1614 PF07758.11 KIK67879.1 - 1.3 9.0 7.2 0.096 12.7 0.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1614) Chromo PF00385.24 KIK67880.1 - 0.00047 20.0 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CorA PF01544.18 KIK67883.1 - 7.4e-09 35.3 0.7 1.2e-08 34.7 0.7 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NTPase_1 PF03266.15 KIK67883.1 - 0.044 13.7 0.4 0.085 12.8 0.4 1.5 1 0 0 1 1 1 0 NTPase F-box-like PF12937.7 KIK67884.1 - 0.00042 20.2 1.3 0.00099 19.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK67884.1 - 0.046 14.2 4.1 0.078 13.4 0.1 3.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) RCC1 PF00415.18 KIK67885.1 - 4e-21 75.4 11.2 0.00042 20.9 0.1 6.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KIK67885.1 - 1.5e-11 44.6 0.4 8.2e-10 39.0 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK67885.1 - 4e-10 40.2 0.0 8.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 KIK67885.1 - 1.5e-09 37.4 0.0 1.5e-09 37.4 0.0 5.8 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.30 KIK67885.1 - 7.5e-09 35.7 0.5 0.0023 18.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIK67885.1 - 2.2e-08 34.2 0.6 0.0042 17.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK67885.1 - 5.2e-08 32.6 0.3 0.024 15.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat BTB PF00651.31 KIK67885.1 - 8.6e-08 32.4 0.0 0.003 17.8 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain EKLF_TAD1 PF16832.5 KIK67885.1 - 0.087 12.7 7.3 0.27 11.1 7.3 1.8 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Pro_isomerase PF00160.21 KIK67886.1 - 3.3e-47 160.7 0.1 4.8e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KIK67886.1 - 8.6e-07 28.5 0.5 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK67886.1 - 3.9e-06 26.6 0.8 0.018 15.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 KIK67886.1 - 0.028 14.5 1.5 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KIK67886.1 - 0.068 12.9 5.6 0.07 12.8 0.2 3.0 3 1 1 4 4 4 0 TPR repeat TPR_8 PF13181.6 KIK67886.1 - 0.072 13.3 0.0 0.072 13.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK67886.1 - 0.081 13.8 1.2 0.26 12.2 0.5 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK67886.1 - 0.083 13.6 0.9 0.71 10.6 0.7 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK67886.1 - 0.086 13.1 1.6 2.4 8.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 KIK67887.1 - 4.1e-05 23.2 0.0 0.00028 20.5 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KIK67887.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain Zn_clus PF00172.18 KIK67888.1 - 1.8e-07 31.2 12.4 3e-07 30.4 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain polyprenyl_synt PF00348.17 KIK67890.1 - 2.3e-89 298.8 0.0 3e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Sigma70_r1_2 PF00140.20 KIK67890.1 - 0.0037 17.2 0.4 0.89 9.6 0.1 2.7 2 0 0 2 2 2 2 Sigma-70 factor, region 1.2 MFS_1 PF07690.16 KIK67891.1 - 1.2e-30 106.6 38.1 1.7e-30 106.2 38.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MRAP PF15183.6 KIK67892.1 - 0.058 13.3 0.6 5.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family CitMHS PF03600.16 KIK67893.1 - 2.4e-13 50.0 12.7 2.4e-13 50.0 12.7 2.2 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.15 KIK67893.1 - 2.5e-12 46.8 19.2 1.3e-08 34.7 7.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CorA PF01544.18 KIK67894.1 - 4e-10 39.5 9.3 9.7e-10 38.2 9.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.18 KIK67895.1 - 1.5e-11 44.2 5.9 3e-11 43.2 5.9 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2877 PF11392.8 KIK67896.1 - 0.011 16.5 1.1 0.14 12.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2877) Dicty_CTDC PF00526.18 KIK67896.1 - 0.067 13.1 7.4 0.067 13.1 7.4 2.0 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat Herpes_UL49_5 PF05702.11 KIK67896.1 - 0.74 9.9 7.2 0.11 12.6 1.0 2.2 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein EphA2_TM PF14575.6 KIK67897.1 - 0.012 16.5 0.0 0.023 15.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KIK67897.1 - 0.071 12.9 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Cadherin_C_2 PF16492.5 KIK67897.1 - 0.1 13.3 0.4 0.24 12.2 0.4 1.8 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF2306 PF10067.9 KIK67900.1 - 2.7e-15 56.9 5.7 2.7e-15 56.9 5.7 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) MerC PF03203.14 KIK67900.1 - 0.028 14.9 4.6 0.047 14.1 0.7 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein Pkinase_Tyr PF07714.17 KIK67902.1 - 8.8e-33 113.7 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK67902.1 - 5.5e-23 81.7 0.0 7.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK67902.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK67902.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Arm PF00514.23 KIK67903.1 - 0.037 14.1 10.1 11 6.2 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 KIK67903.1 - 0.084 13.1 1.0 0.68 10.2 0.3 2.7 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Trp_halogenase PF04820.14 KIK67905.1 - 4.8e-31 108.1 0.0 4.5e-17 62.1 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK67905.1 - 1.4e-08 34.3 0.0 1.4e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK67905.1 - 1.4e-07 31.6 0.6 5.8e-07 29.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK67905.1 - 7.2e-07 29.1 0.0 7e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK67905.1 - 7.5e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK67905.1 - 8.7e-05 21.4 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KIK67905.1 - 0.00014 21.1 0.3 0.0059 15.7 0.3 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK67905.1 - 0.00025 20.3 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIK67905.1 - 0.001 19.6 0.2 0.011 16.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK67905.1 - 0.0022 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK67905.1 - 0.0041 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIK67905.1 - 0.015 15.8 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 KIK67905.1 - 0.056 12.7 0.0 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 KIK67905.1 - 0.18 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPR_8 PF13181.6 KIK67907.1 - 0.0085 16.2 1.7 2.9 8.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK67907.1 - 0.013 15.3 11.2 0.35 10.8 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat AI-2E_transport PF01594.16 KIK67907.1 - 0.021 14.0 0.5 0.033 13.3 0.5 1.2 1 0 0 1 1 1 0 AI-2E family transporter Cas_Csa4 PF09703.10 KIK67907.1 - 0.021 14.1 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) Zwint PF15556.6 KIK67907.1 - 0.022 14.2 0.8 0.022 14.2 0.8 1.8 2 0 0 2 2 2 0 ZW10 interactor PUL PF08324.11 KIK67907.1 - 0.05 12.8 4.7 0.02 14.1 1.2 2.1 2 0 0 2 2 2 0 PUL domain TMCO5 PF14992.6 KIK67907.1 - 0.064 12.8 1.1 0.14 11.7 1.1 1.5 1 0 0 1 1 1 0 TMCO5 family TPR_12 PF13424.6 KIK67907.1 - 0.067 13.5 5.2 0.63 10.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CDC37_N PF03234.14 KIK67907.1 - 0.13 13.2 0.9 0.48 11.3 0.9 2.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Prominin PF05478.11 KIK67907.1 - 0.14 10.0 1.6 0.24 9.3 1.6 1.2 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 KIK67907.1 - 0.17 11.9 0.6 0.67 10.0 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RE_HindVP PF09519.10 KIK67907.1 - 0.5 9.3 2.3 2.5 7.0 0.7 2.1 2 0 0 2 2 2 0 HindVP restriction endonuclease TPR_2 PF07719.17 KIK67907.1 - 0.7 10.1 3.3 14 6.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FlgN PF05130.12 KIK67907.1 - 1.1 9.8 9.8 0.2 12.2 2.2 3.3 4 0 0 4 4 4 0 FlgN protein Baculo_PEP_C PF04513.12 KIK67907.1 - 2 8.4 8.5 3 7.9 1.4 3.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.14 KIK67907.1 - 4.1 6.6 10.2 11 5.2 1.2 3.1 3 0 0 3 3 3 0 Dynamitin Aminotran_5 PF00266.19 KIK67910.1 - 1.5e-18 66.9 0.0 1.6e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIK67910.1 - 1.8e-08 33.9 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIK67910.1 - 0.053 12.8 0.0 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family LamB_YcsF PF03746.16 KIK67912.1 - 6e-78 261.8 0.0 6.8e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 KIK67913.1 - 5.7e-63 213.0 0.0 8.7e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KIK67913.1 - 3.3e-42 144.4 1.2 1.8e-30 106.1 0.0 2.4 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KIK67913.1 - 1e-25 89.9 0.0 2.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KIK67913.1 - 2.8e-25 89.0 0.1 1.9e-24 86.3 0.1 2.2 1 1 0 1 1 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KIK67913.1 - 2.2e-16 60.2 0.3 8e-15 55.1 0.3 2.8 1 1 1 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 KIK67913.1 - 8.7e-05 22.3 0.2 0.0004 20.2 0.2 2.1 1 1 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KIK67913.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Romo1 PF10247.9 KIK67914.1 - 0.0051 17.1 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Adeno_E3_CR2 PF02439.15 KIK67914.1 - 0.0071 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Gly-zipper_Omp PF13488.6 KIK67914.1 - 0.016 15.2 2.8 0.016 15.2 2.8 3.1 3 0 0 3 3 3 0 Glycine zipper SKG6 PF08693.10 KIK67914.1 - 0.74 9.3 5.5 0.37 10.3 0.7 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KIK67914.1 - 5.8 6.9 5.2 1.9 8.5 1.8 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Per1 PF04080.13 KIK67915.1 - 3e-17 63.2 1.6 3.2e-17 63.2 1.6 1.0 1 0 0 1 1 1 1 Per1-like family DUF4035 PF13227.6 KIK67915.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Transp_cyt_pur PF02133.15 KIK67916.1 - 1.4e-89 300.9 32.1 1.7e-89 300.6 32.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CBM_1 PF00734.18 KIK67917.1 - 8.7e-12 44.8 10.6 8.7e-12 44.8 10.6 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Promethin PF16015.5 KIK67918.1 - 3.6e-07 30.0 20.4 5.6e-07 29.5 20.4 1.2 1 0 0 1 1 1 1 Promethin Oxidored_q3 PF00499.20 KIK67918.1 - 0.00053 19.7 6.3 0.00076 19.2 6.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2070 PF09843.9 KIK67918.1 - 6.1 5.0 14.3 7.2 4.8 14.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1700 PF08006.11 KIK67918.1 - 6.8 6.2 12.6 11 5.5 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MFS_1 PF07690.16 KIK67919.1 - 9.1e-19 67.6 59.0 9.1e-19 67.6 59.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KIK67920.1 - 2.1e-65 221.0 1.4 2.5e-65 220.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KIK67920.1 - 0.018 13.6 0.1 2.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KIK67920.1 - 0.32 10.5 8.2 0.41 10.1 0.4 3.2 3 1 0 3 3 3 0 Glycosyl hydrolase family 76 Ammonium_transp PF00909.21 KIK67922.1 - 2e-114 382.4 28.0 2.3e-114 382.2 28.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Methyltransf_25 PF13649.6 KIK67923.1 - 3.2e-13 50.2 0.0 5.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK67923.1 - 5.8e-12 46.1 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK67923.1 - 8.1e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK67923.1 - 3.3e-08 33.2 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIK67923.1 - 5.1e-08 32.9 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK67923.1 - 1e-06 29.4 0.0 1.9e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RIX1 PF08167.12 KIK67924.1 - 1.1e-35 123.0 6.1 1.1e-35 123.0 6.1 2.2 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Orn_Arg_deC_N PF02784.16 KIK67924.1 - 0.051 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Sec10 PF07393.11 KIK67925.1 - 3.6e-220 733.1 0.3 5.1e-220 732.6 0.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 I_LWEQ PF01608.17 KIK67925.1 - 0.0032 17.7 0.6 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 I/LWEQ domain Ribonuc_red_2_N PF08471.10 KIK67925.1 - 0.042 14.0 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Peptidase_S46 PF10459.9 KIK67925.1 - 0.052 12.2 2.1 0.09 11.4 2.1 1.4 1 0 0 1 1 1 0 Peptidase S46 NuA4 PF09340.10 KIK67925.1 - 0.26 11.2 0.9 0.99 9.3 0.1 2.4 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 DUF3540 PF12059.8 KIK67925.1 - 0.58 10.0 3.6 0.27 11.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) ECH_1 PF00378.20 KIK67926.1 - 2.3e-53 181.1 0.0 2.7e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK67926.1 - 2e-24 86.7 0.0 2.6e-22 79.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase OppC_N PF12911.7 KIK67927.1 - 0.052 13.5 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Gram_pos_anchor PF00746.21 KIK67927.1 - 0.15 12.0 1.3 0.26 11.3 1.3 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif OmpH PF03938.14 KIK67928.1 - 0.014 15.7 5.1 0.028 14.7 5.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RmuC PF02646.16 KIK67928.1 - 0.036 13.2 6.8 0.059 12.5 6.8 1.2 1 0 0 1 1 1 0 RmuC family ISG65-75 PF11727.8 KIK67928.1 - 0.056 12.7 1.9 0.085 12.1 1.9 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein FlxA PF14282.6 KIK67928.1 - 0.35 10.9 16.1 1.2 9.2 15.7 1.9 1 1 0 1 1 1 0 FlxA-like protein DUF2992 PF11208.8 KIK67928.1 - 0.49 10.6 6.1 0.98 9.7 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF1664 PF07889.12 KIK67928.1 - 0.78 9.8 3.6 1.7 8.7 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KIK67928.1 - 0.85 9.8 6.5 1.5 9.0 6.5 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 KIK67928.1 - 1 9.8 6.3 2.3 8.6 6.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 KIK67928.1 - 1.2 8.9 10.2 0.74 9.6 7.5 2.0 1 1 1 2 2 2 0 Septum formation initiator Exonuc_VII_L PF02601.15 KIK67928.1 - 1.3 8.5 7.1 2.1 7.8 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lge1 PF11488.8 KIK67928.1 - 3.2 8.0 9.5 15 5.9 9.5 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 FUSC PF04632.12 KIK67928.1 - 3.5 6.1 11.5 0.2 10.1 6.3 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 KIK67928.1 - 7.3 7.1 6.8 59 4.2 3.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KIK67928.1 - 8 7.2 9.8 36 5.1 7.4 2.8 2 1 0 2 2 2 0 Initiation control protein YabA Amidohydro_2 PF04909.14 KIK67929.1 - 9.6e-20 71.5 0.0 6.1e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KIK67929.1 - 0.00054 19.4 0.0 0.0032 16.9 0.0 2.0 2 0 0 2 2 2 1 TatD related DNase QRPTase_C PF01729.19 KIK67930.1 - 1.4e-49 168.1 0.1 1.7e-49 167.8 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KIK67930.1 - 1e-19 70.3 0.0 3.2e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Pantoate_transf PF02548.15 KIK67931.1 - 4.9e-105 350.6 0.1 5.7e-105 350.4 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KIK67931.1 - 4.7e-05 22.9 0.1 9.3e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Cas_Csm6 PF09659.10 KIK67931.1 - 0.036 12.8 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) GPI-anchored PF10342.9 KIK67932.1 - 9.6e-10 39.1 0.2 9.6e-10 39.1 0.2 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Atrophin-1 PF03154.15 KIK67932.1 - 0.19 10.0 0.9 0.23 9.7 0.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family MGC-24 PF05283.11 KIK67932.1 - 3.9 7.9 7.8 0.79 10.2 4.4 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SIP1 PF04938.12 KIK67933.1 - 1.5e-22 80.4 0.0 2.4e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SRP-alpha_N PF04086.13 KIK67933.1 - 0.13 12.1 0.6 0.18 11.7 0.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3245 PF11595.8 KIK67934.1 - 4e-07 30.6 2.9 4e-07 30.6 2.9 3.9 2 2 1 3 3 3 1 Protein of unknown function (DUF3245) NOP19 PF10863.8 KIK67934.1 - 0.0003 20.7 0.4 0.0003 20.7 0.4 2.9 1 1 2 3 3 3 1 Nucleolar protein 19 Coilin_N PF15862.5 KIK67934.1 - 0.073 12.9 0.8 0.073 12.9 0.8 3.2 3 1 0 3 3 3 0 Coilin N-terminus G-patch_2 PF12656.7 KIK67934.1 - 0.56 10.3 0.0 0.56 10.3 0.0 2.9 3 0 0 3 3 3 0 G-patch domain DSPc PF00782.20 KIK67937.1 - 1.5e-31 108.9 0.0 1.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK67937.1 - 0.0035 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIK67937.1 - 0.043 14.1 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Arf PF00025.21 KIK67938.1 - 4.8e-79 263.9 0.1 5.5e-79 263.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK67938.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK67938.1 - 3.1e-14 52.8 0.0 3.8e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KIK67938.1 - 6.4e-13 48.6 1.2 3.9e-09 36.1 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KIK67938.1 - 1.1e-12 47.8 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIK67938.1 - 1.4e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK67938.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIK67938.1 - 0.0071 15.7 0.7 0.02 14.2 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Sec15 PF04091.12 KIK67939.1 - 3.5e-92 309.2 0.4 7.2e-92 308.2 0.4 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KIK67939.1 - 9e-07 29.1 0.3 9e-07 29.1 0.3 3.4 3 1 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KIK67939.1 - 8.6e-06 25.7 0.7 8.6e-06 25.7 0.7 3.4 3 0 0 3 3 3 1 Vps51/Vps67 Sec8_exocyst PF04048.14 KIK67939.1 - 0.00015 21.7 4.9 0.00022 21.1 0.6 3.5 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Prominin PF05478.11 KIK67939.1 - 0.0026 15.8 5.8 0.036 12.0 0.2 2.4 2 0 0 2 2 2 2 Prominin COG2 PF06148.11 KIK67939.1 - 0.0054 16.8 0.9 0.0054 16.8 0.9 3.6 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.12 KIK67939.1 - 0.017 13.8 5.7 0.064 11.9 1.3 2.5 2 0 0 2 2 2 0 Dor1-like family GIT1_C PF12205.8 KIK67939.1 - 0.043 13.9 1.8 9.9 6.3 0.1 3.2 2 1 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Sec5 PF15469.6 KIK67939.1 - 0.063 13.1 0.7 0.25 11.2 0.7 2.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 RAC_head PF16717.5 KIK67939.1 - 0.12 13.3 1.3 1.7 9.7 0.2 3.0 2 1 0 2 2 2 0 Ribosome-associated complex head domain DASH_Dad4 PF08650.10 KIK67939.1 - 0.15 12.0 0.5 1.6 8.7 0.1 2.8 3 1 0 3 3 3 0 DASH complex subunit Dad4 APG6_N PF17675.1 KIK67939.1 - 0.53 10.8 3.1 1.3 9.5 0.1 3.0 3 0 0 3 3 3 0 Apg6 coiled-coil region Mod_r PF07200.13 KIK67939.1 - 2.3 8.3 6.7 5.1 7.2 0.2 3.8 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HAD_2 PF13419.6 KIK67940.1 - 4.8e-20 72.4 0.0 6.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK67940.1 - 6.9e-11 42.8 0.5 2e-08 34.8 0.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK67940.1 - 3.7e-06 26.9 0.0 8.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIK67940.1 - 0.049 14.0 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Lactamase_B_6 PF16661.5 KIK67941.1 - 5.5e-50 169.5 0.0 1e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KIK67941.1 - 1.2e-24 87.3 4.5 8.7e-22 78.1 0.1 3.4 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KIK67941.1 - 1.7e-20 73.4 0.0 9.9e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KIK67941.1 - 2.6e-07 30.5 0.1 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KIK67941.1 - 0.0017 17.9 0.0 0.061 12.8 0.0 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIK67941.1 - 0.082 12.8 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Abhydrolase_3 PF07859.13 KIK67942.1 - 3.8e-39 134.7 0.0 4.6e-31 108.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK67942.1 - 3.4e-08 32.8 0.0 1.9e-07 30.3 0.0 2.1 2 1 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KIK67942.1 - 0.054 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK67942.1 - 0.095 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family Tubulin PF00091.25 KIK67943.1 - 9.5e-66 221.7 0.0 1.3e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK67943.1 - 2.7e-49 166.5 0.0 4.1e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIK67943.1 - 0.0012 18.5 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 KIK67943.1 - 0.098 12.5 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Tubulin PF00091.25 KIK67944.1 - 1.3e-65 221.3 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK67944.1 - 1e-47 161.4 0.0 1.5e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIK67944.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain tRNA-synt_1c PF00749.21 KIK67946.1 - 4.9e-108 360.7 0.0 6.6e-108 360.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KIK67946.1 - 7.4e-41 139.8 0.0 1.2e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KIK67946.1 - 2e-31 109.2 0.0 4e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KIK67946.1 - 2.2e-06 28.5 0.6 4.5e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF3433 PF11915.8 KIK67947.1 - 9.1e-20 70.9 2.6 9.1e-20 70.9 2.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) AAA PF00004.29 KIK67948.1 - 2.5e-19 70.0 0.0 5.5e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK67948.1 - 0.034 14.5 0.1 0.24 11.8 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK67948.1 - 0.13 12.6 0.2 1.7 8.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK67948.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SANT_DAMP1_like PF16282.5 KIK67949.1 - 2.8e-31 107.5 9.3 5.1e-31 106.7 9.3 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 KIK67949.1 - 0.0021 18.3 1.2 0.0059 16.8 1.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DMAP1 PF05499.12 KIK67949.1 - 0.015 15.2 4.2 0.19 11.6 4.2 2.3 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Nup192 PF11894.8 KIK67949.1 - 0.04 11.1 0.9 0.055 10.6 0.9 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF202 PF02656.15 KIK67950.1 - 1.7e-11 44.3 5.9 1.5e-10 41.4 4.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF4267 PF14087.6 KIK67951.1 - 6.5e-28 97.1 4.8 7.6e-28 96.8 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) zf-U1 PF06220.12 KIK67953.1 - 4.8e-21 74.2 4.1 1e-20 73.2 4.1 1.6 1 0 0 1 1 1 1 U1 zinc finger CARD_2 PF16739.5 KIK67953.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain LSM PF01423.22 KIK67954.1 - 4.4e-19 67.9 0.1 5.1e-19 67.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KIK67954.1 - 0.017 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain F-box-like PF12937.7 KIK67956.1 - 2.2e-12 46.6 4.5 9.5e-12 44.6 4.5 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK67956.1 - 8e-08 32.5 12.3 0.074 13.5 0.0 7.3 4 3 4 9 9 9 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KIK67956.1 - 1.2e-07 31.4 2.8 1.2e-07 31.4 2.8 4.1 4 0 0 4 4 4 2 F-box domain LRR_6 PF13516.6 KIK67956.1 - 1.4e-05 24.8 13.3 1.4 9.2 0.0 9.0 10 0 0 10 10 10 1 Leucine Rich repeat DUF4611 PF15387.6 KIK67956.1 - 0.019 15.1 0.8 0.051 13.8 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) LRR_8 PF13855.6 KIK67956.1 - 0.051 13.3 4.1 1.4 8.7 0.0 4.4 6 0 0 6 6 6 0 Leucine rich repeat SAM_Ste50p PF09235.10 KIK67956.1 - 4.9 7.5 8.6 2.8 8.2 0.1 4.1 5 1 0 5 5 5 0 Ste50p, sterile alpha motif SIR2 PF02146.17 KIK67958.1 - 8.4e-34 117.0 0.0 2e-22 80.0 0.0 2.2 1 1 1 2 2 2 2 Sir2 family HypA PF01155.19 KIK67958.1 - 0.073 13.1 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Asparaginase PF00710.20 KIK67958.1 - 0.095 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Asparaginase, N-terminal RhoGEF PF00621.20 KIK67960.1 - 3.7e-34 118.5 0.2 9.1e-34 117.3 0.2 1.7 1 0 0 1 1 1 1 RhoGEF domain KxDL PF10241.9 KIK67960.1 - 0.065 13.5 6.7 2 8.8 0.1 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein TerB_C PF15615.6 KIK67960.1 - 2.9 8.2 10.5 0.31 11.3 4.7 2.3 2 0 0 2 2 2 0 TerB-C domain RhoGEF PF00621.20 KIK67961.1 - 8.7e-24 84.7 0.1 2.1e-23 83.5 0.1 1.7 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 KIK67961.1 - 0.0085 16.6 0.1 0.1 13.1 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 KIK67961.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_6 PF13516.6 KIK67962.1 - 3.2e-14 51.7 6.9 0.025 14.6 0.1 7.6 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 KIK67962.1 - 3.5e-13 49.5 9.4 0.0032 17.8 0.0 6.9 3 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK67962.1 - 5.1e-07 29.3 11.4 1.8 9.4 0.0 7.5 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 KIK67962.1 - 0.017 14.9 7.3 8.1 6.3 0.1 5.2 4 1 2 6 6 6 0 Leucine rich repeat DUF5310 PF17237.2 KIK67963.1 - 1.9e-19 69.2 4.6 2.6e-19 68.8 4.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Amidohydro_1 PF01979.20 KIK67964.1 - 9e-12 45.0 0.0 3.8e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK67964.1 - 7.3e-08 32.3 0.0 9.7e-07 28.6 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Cupin_3 PF05899.12 KIK67964.1 - 0.084 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Myb_DNA-binding PF00249.31 KIK67966.1 - 1.1e-22 79.9 4.1 3.1e-10 40.1 0.3 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK67966.1 - 1.1e-14 54.4 6.1 2.5e-06 27.6 0.0 4.2 4 1 1 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK67966.1 - 0.034 14.5 0.3 0.034 14.5 0.3 3.6 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain DUF2052 PF09747.9 KIK67967.1 - 2.6e-10 40.8 13.8 4.3e-10 40.0 13.8 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Cyt-b5 PF00173.28 KIK67970.1 - 1e-10 41.6 0.2 1.6e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PAF-AH_p_II PF03403.13 KIK67971.1 - 4.3e-33 114.3 0.0 1.6e-32 112.5 0.0 1.7 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KIK67971.1 - 0.00014 21.2 0.0 0.084 12.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK67971.1 - 0.00038 19.5 0.0 0.0098 14.8 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase enzyme Biliv-reduc_cat PF09166.10 KIK67971.1 - 0.026 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Biliverdin reductase, catalytic Thioesterase PF00975.20 KIK67971.1 - 0.061 13.4 0.2 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase PF07224.11 KIK67971.1 - 0.076 12.0 0.0 0.76 8.7 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_2 PF02230.16 KIK67971.1 - 0.18 11.6 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mannosidase_ig PF17786.1 KIK67972.1 - 2e-16 60.4 0.0 3.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIK67972.1 - 9.5e-10 39.1 0.0 2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KIK67972.1 - 9.3e-09 34.9 0.0 2.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KIK67972.1 - 0.015 15.2 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 KIK67972.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain Lactamase_B_2 PF12706.7 KIK67973.1 - 1.1e-09 38.1 0.1 6.6e-05 22.5 0.1 3.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK67973.1 - 9.8e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KIK67973.1 - 2.9e-06 26.8 0.0 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease PDEase_II PF02112.15 KIK67973.1 - 0.024 13.8 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II THOC7 PF05615.13 KIK67974.1 - 1.3e-31 109.6 7.0 1.3e-31 109.6 7.0 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 Filament PF00038.21 KIK67974.1 - 0.00017 21.3 9.5 0.00017 21.3 9.5 1.6 2 0 0 2 2 2 1 Intermediate filament protein Atg14 PF10186.9 KIK67974.1 - 0.0018 17.5 2.3 0.0027 16.8 2.3 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_MT_bd PF06657.13 KIK67974.1 - 0.014 15.8 0.4 0.014 15.8 0.4 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TolA_bind_tri PF16331.5 KIK67974.1 - 0.086 12.9 10.5 0.27 11.3 4.7 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4795 PF16043.5 KIK67974.1 - 0.58 9.7 10.8 0.04 13.5 5.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Prefoldin_2 PF01920.20 KIK67974.1 - 0.71 9.9 11.7 6.3 6.8 11.7 2.4 1 1 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 KIK67974.1 - 8.1 6.9 10.4 1 9.8 0.8 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) UIM PF02809.20 KIK67975.1 - 0.16 11.9 0.0 0.16 11.9 0.0 4.2 5 0 0 5 5 5 0 Ubiquitin interaction motif Pkinase PF00069.25 KIK67976.1 - 4.2e-61 206.6 0.0 2.9e-40 138.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK67976.1 - 3.5e-27 95.3 0.0 8.5e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KIK67976.1 - 1.7e-12 47.5 0.0 3.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KIK67976.1 - 7.3e-07 28.8 0.1 0.0055 16.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIK67976.1 - 0.0012 18.9 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_3 PF08447.12 KIK67976.1 - 0.0026 18.0 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold Haspin_kinase PF12330.8 KIK67976.1 - 0.015 14.2 0.0 0.015 14.2 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KIK67976.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK67976.1 - 0.069 12.7 0.5 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 RIO1 family PAS_9 PF13426.7 KIK67976.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KIK67976.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_S18 PF01084.20 KIK67977.1 - 4.2e-13 49.3 0.1 6.9e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 JAB PF01398.21 KIK67978.1 - 2e-32 111.6 0.2 3.4e-32 110.9 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIK67978.1 - 7.2e-14 52.2 0.9 1.3e-13 51.3 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KIK67978.1 - 4.7e-06 26.4 0.0 7.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KIK67978.1 - 0.054 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Vps52 PF04129.12 KIK67980.1 - 7.6e-63 213.0 4.6 1.9e-36 125.9 0.3 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.9 KIK67980.1 - 5.1e-06 25.2 0.0 0.00045 18.8 0.0 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec3 MscS_porin PF12795.7 KIK67980.1 - 0.083 12.4 0.6 0.22 11.0 0.6 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ApoLp-III PF07464.11 KIK67980.1 - 1.3 9.1 4.0 0.83 9.7 0.4 2.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ZT_dimer PF16916.5 KIK67981.1 - 0.02 15.0 0.4 15 5.8 0.0 3.2 2 1 1 3 3 3 0 Dimerisation domain of Zinc Transporter Aldose_epim PF01263.20 KIK67982.1 - 4.7e-61 206.7 0.8 5.7e-61 206.4 0.8 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase BRCT_2 PF16589.5 KIK67983.1 - 7.2e-10 39.1 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK67983.1 - 4.6e-08 33.3 0.0 1.5e-07 31.7 0.0 1.8 1 1 1 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK67983.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KIK67983.1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain SWIRM-assoc_2 PF16496.5 KIK67983.1 - 0.0027 16.6 0.5 0.0051 15.7 0.0 1.6 1 1 1 2 2 2 1 SWIRM-associated domain at the N-terminal BRCT_3 PF18428.1 KIK67983.1 - 0.036 14.1 0.0 0.086 12.9 0.0 1.6 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PNISR PF15996.5 KIK67983.1 - 0.056 13.7 1.6 0.095 13.0 1.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Mur_ligase_M PF08245.12 KIK67984.1 - 2.2e-07 31.0 0.1 0.0013 18.8 0.0 3.4 2 1 1 3 3 3 2 Mur ligase middle domain Slx4 PF09494.10 KIK67985.1 - 3e-05 23.9 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease IBN_N PF03810.19 KIK67986.1 - 1.3e-08 34.7 3.0 7.8e-06 25.7 0.5 3.5 2 1 1 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.12 KIK67986.1 - 0.00032 20.8 3.0 0.00089 19.3 1.2 2.7 2 0 0 2 2 2 1 Exportin 1-like protein DEAD_assoc PF08494.11 KIK67986.1 - 0.087 12.6 0.9 0.57 9.9 0.1 2.5 3 0 0 3 3 3 0 DEAD/H associated Pex2_Pex12 PF04757.14 KIK67987.1 - 6.8e-32 110.9 8.6 9.5e-32 110.4 8.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KIK67987.1 - 0.0011 18.7 2.6 0.0031 17.3 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 KIK67987.1 - 0.0016 18.6 1.9 0.0016 18.6 1.9 1.6 1 1 1 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.6 KIK67987.1 - 0.0032 17.4 7.8 0.012 15.5 7.9 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK67987.1 - 0.0093 16.0 5.0 0.05 13.6 5.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger RDD PF06271.12 KIK67987.1 - 0.012 15.9 0.1 0.028 14.6 0.1 1.7 1 1 0 1 1 1 0 RDD family zf-C3HC4 PF00097.25 KIK67987.1 - 0.017 15.0 7.2 0.13 12.2 7.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK67987.1 - 0.053 13.9 8.4 0.29 11.5 4.2 2.5 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 KIK67987.1 - 0.22 11.4 6.6 0.58 10.1 3.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK67987.1 - 0.44 10.7 8.1 0.14 12.3 3.5 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING tRNA-synt_2d PF01409.20 KIK67988.1 - 8e-85 284.2 0.0 1.6e-82 276.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KIK67988.1 - 1.7e-17 63.4 2.1 7.4e-17 61.4 0.4 2.7 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KIK67988.1 - 1.2e-08 34.7 0.0 9.3e-05 22.0 0.0 2.9 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KIK67988.1 - 0.00084 18.5 0.1 0.014 14.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KIK67988.1 - 0.0043 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 KIK67988.1 - 0.0075 16.2 1.6 0.017 15.1 1.6 1.6 1 1 0 1 1 1 1 PheRS DNA binding domain 2 HTH_45 PF14947.6 KIK67988.1 - 0.051 13.6 0.0 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix PheRS_DBD1 PF18552.1 KIK67988.1 - 0.13 12.0 0.1 0.58 10.0 0.1 2.1 1 1 0 1 1 1 0 PheRS DNA binding domain 1 ThrE PF06738.12 KIK67989.1 - 5.2e-45 153.7 4.7 5.2e-45 153.7 4.7 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIK67989.1 - 6.5e-06 26.3 7.0 6.5e-06 26.3 7.0 2.9 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Acetyltransf_1 PF00583.25 KIK67991.1 - 3e-12 46.8 0.0 5.3e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK67991.1 - 2.4e-08 34.3 0.0 8.8e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK67991.1 - 6.7e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK67991.1 - 9.3e-05 23.1 0.0 0.00053 20.7 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK67991.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KIK67991.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyoxalase_3 PF13468.6 KIK67991.1 - 0.093 12.8 0.0 11 6.1 0.0 2.6 2 1 1 3 3 3 0 Glyoxalase-like domain Acetyltransf_4 PF13420.7 KIK67991.1 - 0.13 12.3 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KIK67991.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family DUF2370 PF10176.9 KIK67992.1 - 4.9e-76 255.3 0.0 1.9e-75 253.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF4064 PF13273.6 KIK67992.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Herpes_gE PF02480.16 KIK67993.1 - 0.023 13.5 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK67993.1 - 0.023 15.6 0.0 0.036 15.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KIK67993.1 - 0.069 13.1 1.0 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 KIK67993.1 - 0.085 12.8 1.5 0.17 11.8 1.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4381 PF14316.6 KIK67993.1 - 0.097 12.9 0.3 0.15 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Gram_pos_anchor PF00746.21 KIK67993.1 - 0.13 12.3 0.6 0.27 11.2 0.6 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Stevor PF17410.2 KIK67993.1 - 0.14 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CD34_antigen PF06365.12 KIK67993.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Ribonuc_L-PSP PF01042.21 KIK67996.1 - 1.3e-15 57.5 0.0 1.1e-09 38.3 0.0 2.9 2 1 0 2 2 2 2 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 KIK67997.1 - 1.3e-39 136.0 0.0 4.9e-37 127.6 0.0 2.8 1 1 0 1 1 1 1 Diphthamide synthase Sugar_tr PF00083.24 KIK67998.1 - 2e-107 359.9 14.3 2.5e-107 359.6 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK67998.1 - 1.7e-18 66.7 27.2 6.8e-15 54.8 3.3 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIK67998.1 - 0.0068 14.8 2.5 0.0074 14.6 0.9 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 KIK67998.1 - 0.075 12.0 6.3 0.22 10.5 2.6 2.2 2 0 0 2 2 2 0 PUCC protein Beta-APP PF03494.13 KIK67998.1 - 0.099 12.5 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) OppC_N PF12911.7 KIK67998.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.3 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C YlaC PF10777.9 KIK67998.1 - 0.46 10.3 2.2 0.5 10.2 0.0 2.1 3 0 0 3 3 3 0 Inner membrane protein YlaC DUF485 PF04341.12 KIK67998.1 - 0.9 9.5 8.7 8.3 6.4 0.9 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 HSP20 PF00011.21 KIK67999.1 - 0.0027 17.8 0.0 0.0086 16.2 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family EB PF01683.18 KIK68000.1 - 2e-05 24.8 22.4 0.016 15.5 8.3 4.2 3 1 1 4 4 4 3 EB module Dickkopf_N PF04706.12 KIK68000.1 - 1.2 9.6 30.1 0.19 12.2 10.3 4.0 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region F-box-like PF12937.7 KIK68001.1 - 4.9e-08 32.7 4.3 8.8e-08 31.9 2.9 2.3 2 0 0 2 2 2 1 F-box-like Lipase_GDSL_2 PF13472.6 KIK68002.1 - 1.1e-19 71.6 0.3 1.7e-19 70.9 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK68002.1 - 1.7e-06 28.1 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_16 PF10294.9 KIK68003.1 - 6.5e-18 65.1 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIK68003.1 - 0.0015 19.2 0.0 0.0031 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK68003.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF5127 PF17168.4 KIK68006.1 - 2.7e-82 275.9 2.2 4.2e-82 275.3 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK68006.1 - 1.3e-72 243.1 0.1 2.6e-72 242.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK68006.1 - 3.3e-63 213.1 0.5 6.6e-63 212.1 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK68006.1 - 6e-08 32.1 0.6 1.2e-07 31.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Phosducin PF02114.16 KIK68008.1 - 9.9e-06 24.7 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KIK68008.1 - 0.0019 18.2 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin eRF1_1 PF03463.15 KIK68009.1 - 3e-47 159.9 0.0 4.5e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KIK68009.1 - 1.4e-20 73.9 0.0 3.1e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KIK68009.1 - 6.2e-18 65.4 0.0 9.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 ETF PF01012.21 KIK68009.1 - 0.0094 15.9 0.7 0.042 13.7 0.0 2.2 3 0 0 3 3 3 1 Electron transfer flavoprotein domain FAD_binding_7 PF03441.14 KIK68010.1 - 8.6e-74 247.4 0.4 2.3e-73 246.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KIK68010.1 - 1.6e-38 132.3 0.0 2.9e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase WD40 PF00400.32 KIK68011.1 - 3.7e-13 49.7 13.8 0.064 14.2 0.3 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68011.1 - 6.7e-08 32.7 0.2 0.38 11.1 0.1 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KIK68011.1 - 0.011 15.0 0.0 0.52 9.5 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5127 PF17168.4 KIK68012.1 - 2.2e-79 266.4 11.3 4.3e-79 265.5 11.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK68012.1 - 9.9e-70 233.7 0.3 3.3e-69 232.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK68012.1 - 2.7e-67 226.3 2.0 2.7e-67 226.3 2.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK68012.1 - 3.6e-09 36.1 0.1 1.2e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) HalX PF08663.10 KIK68012.1 - 0.2 12.0 0.1 0.4 11.0 0.1 1.4 1 0 0 1 1 1 0 HalX domain Glyco_hydro_18 PF00704.28 KIK68013.1 - 8e-56 190.0 0.0 9.1e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 OMPdecase PF00215.24 KIK68014.1 - 7e-66 222.0 0.0 8.7e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.18 KIK68015.1 - 3.8e-76 256.6 0.1 7.7e-73 245.7 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) MFS_1 PF07690.16 KIK68016.1 - 1.4e-32 113.0 22.1 7.2e-32 110.7 17.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK68016.1 - 6.3e-07 28.6 14.6 4.3e-05 22.6 15.0 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 KIK68016.1 - 0.00022 20.3 0.1 0.00041 19.4 0.1 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Gly_transf_sug PF04488.15 KIK68017.1 - 6.9e-22 77.9 0.1 1.4e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KIK68017.1 - 0.096 12.0 1.0 0.23 10.7 0.3 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain PIN_4 PF13638.6 KIK68018.1 - 3.9e-21 75.7 0.0 8.9e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 PIN domain NAD_binding_1 PF00175.21 KIK68019.1 - 7.3e-07 29.8 0.0 5.2e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KIK68019.1 - 9.9e-07 29.0 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Putative_PNPOx PF01243.20 KIK68019.1 - 5.1e-06 26.6 0.0 0.014 15.6 0.0 3.1 3 1 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase MLVIN_C PF18697.1 KIK68019.1 - 0.21 11.7 0.0 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain adh_short PF00106.25 KIK68020.1 - 4.3e-29 101.4 0.0 4.6e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK68020.1 - 5.1e-16 58.9 0.1 2.2e-11 43.8 0.1 2.7 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK68020.1 - 8.6e-12 45.3 0.1 1.4e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK68020.1 - 5.6e-05 22.7 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK68020.1 - 7.9e-05 22.2 0.0 0.00019 20.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK68020.1 - 0.00068 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KIK68020.1 - 0.0041 17.4 0.5 0.0077 16.5 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIK68020.1 - 0.0057 16.6 0.3 0.011 15.6 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK68020.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Wtap PF17098.5 KIK68022.1 - 2.8e-17 63.1 5.2 7.7e-16 58.4 5.2 2.2 1 1 0 1 1 1 1 WTAP/Mum2p family bZIP_1 PF00170.21 KIK68022.1 - 0.064 13.4 0.3 0.064 13.4 0.3 2.3 2 1 0 2 2 2 0 bZIP transcription factor Mer2 PF09074.10 KIK68022.1 - 5.4 6.8 6.9 0.41 10.4 0.2 2.0 2 0 0 2 2 2 0 Mer2 ATG16 PF08614.11 KIK68022.1 - 8.8 6.5 13.1 3.1 8.0 0.7 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.7 KIK68024.1 - 1.5e-23 83.2 0.1 1.4e-15 57.6 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK68024.1 - 1.9e-22 79.3 0.9 3.7e-15 56.1 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK68024.1 - 6.1e-21 74.2 1.8 2.8e-11 43.4 0.3 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK68024.1 - 1.1e-16 59.2 0.2 1.5e-05 25.0 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KIK68024.1 - 3.9e-15 55.5 0.6 7.7e-06 26.1 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat MFS_1_like PF12832.7 KIK68025.1 - 0.034 13.0 9.2 0.0093 14.9 4.3 2.4 2 1 0 2 2 2 0 MFS_1 like family DUF4231 PF14015.6 KIK68025.1 - 0.47 10.9 5.4 3.1 8.3 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Ribonucleas_3_3 PF14622.6 KIK68026.1 - 2.6e-17 63.2 0.0 3.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK68026.1 - 0.00059 20.4 0.0 0.00083 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Gsf2 PF11055.8 KIK68027.1 - 0.1 11.3 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 Rtf2 PF04641.12 KIK68028.1 - 1.7e-77 260.3 2.6 2e-77 260.1 2.6 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KIK68028.1 - 0.0024 17.6 0.3 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KIK68028.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein MRP-S31 PF15433.6 KIK68028.1 - 0.075 12.7 3.6 0.12 12.1 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 zf-UDP PF14569.6 KIK68028.1 - 0.092 12.9 0.9 0.29 11.3 0.9 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_15 PF17032.5 KIK68028.1 - 0.17 12.7 1.2 0.47 11.2 0.5 2.1 2 0 0 2 2 2 0 zinc-ribbon family DUF3729 PF12526.8 KIK68028.1 - 3 9.4 9.2 0.54 11.8 5.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Tmemb_9 PF05434.11 KIK68028.1 - 3.9 7.4 5.8 5.1 7.0 0.1 2.8 2 1 1 3 3 3 0 TMEM9 HAD_2 PF13419.6 KIK68029.1 - 2.6e-09 37.4 0.0 4.6e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK68029.1 - 9.4e-09 35.9 0.0 9.2e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK68029.1 - 0.00016 21.7 0.0 0.00038 20.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like NIF PF03031.18 KIK68029.1 - 0.0043 16.8 0.1 0.045 13.5 0.1 2.1 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 KIK68029.1 - 0.0074 16.2 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 Acid Phosphatase DUF2608 PF11019.8 KIK68029.1 - 0.049 13.1 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Ribosomal_L6e PF01159.19 KIK68030.1 - 2.1e-37 128.1 0.0 3.5e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KIK68030.1 - 1.2e-06 28.6 0.4 1.2e-06 28.6 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain 60KD_IMP PF02096.20 KIK68031.1 - 8.1e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Histone PF00125.24 KIK68032.1 - 6.7e-43 146.2 0.7 7.5e-43 146.0 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK68032.1 - 6.4e-05 23.0 0.1 8.7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK68032.1 - 0.0012 19.0 0.4 0.0026 18.0 0.4 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KIK68032.1 - 0.0027 18.0 0.1 0.0044 17.4 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KIK68032.1 - 0.079 13.0 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-CpG_bind_C PF12269.8 KIK68034.1 - 0.014 15.2 0.2 0.019 14.7 0.2 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DivIC PF04977.15 KIK68034.1 - 0.034 13.9 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Met_synt_B12 PF02965.17 KIK68034.1 - 0.046 13.2 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain UPF0183 PF03676.14 KIK68035.1 - 1.5e-60 205.6 0.0 2e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Apt1 PF10351.9 KIK68037.1 - 2.9e-78 263.9 2.3 2.9e-78 263.9 2.3 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KIK68037.1 - 6e-43 147.4 0.0 1.2e-20 73.8 0.2 2.5 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.16 KIK68037.1 - 6e-40 136.9 0.5 1.4e-39 135.6 0.5 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Fmp27_GFWDK PF10347.9 KIK68037.1 - 5.4e-38 130.6 0.0 1.1e-37 129.5 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KIK68037.1 - 2.1e-26 92.7 0.0 9.8e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KIK68037.1 - 3.5e-13 50.1 0.0 1.1e-12 48.6 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2985 PF11204.8 KIK68038.1 - 1.1e-26 92.7 0.9 1.1e-26 92.7 0.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Pkinase PF00069.25 KIK68039.1 - 6.1e-53 179.9 0.0 8.1e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68039.1 - 2.7e-30 105.5 0.0 3.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK68039.1 - 0.0016 17.8 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK68039.1 - 0.0066 15.8 0.2 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK68039.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family LEM PF03020.15 KIK68039.1 - 0.065 12.8 0.4 0.52 9.9 0.1 2.2 2 0 0 2 2 2 0 LEM domain Choline_kinase PF01633.20 KIK68039.1 - 0.09 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Spuma_A9PTase PF03539.14 KIK68039.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) ADH_N PF08240.12 KIK68040.1 - 7e-28 96.7 0.7 1.3e-27 95.9 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK68040.1 - 4e-20 72.1 0.0 7.4e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK68040.1 - 1.7e-07 30.9 0.9 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK68040.1 - 5.3e-07 30.7 0.2 1.1e-06 29.7 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIK68040.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 KIK68040.1 - 0.03 15.0 0.0 0.067 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.27 KIK68042.1 - 2e-51 174.3 0.0 3.1e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KIK68042.1 - 7.3e-14 51.6 0.1 2e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KIK68042.1 - 1.8e-12 47.1 0.0 6.9e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK68042.1 - 2.9e-06 27.6 0.0 6.8e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK68042.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIK68042.1 - 0.018 14.5 0.1 0.069 12.6 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KIK68042.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain ICMT PF04140.14 KIK68043.1 - 7e-27 93.7 1.2 7e-27 93.7 1.2 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK68043.1 - 1.7e-13 50.9 2.4 1.7e-13 50.9 2.4 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KIK68043.1 - 9.4e-06 25.3 1.6 9.4e-06 25.3 1.6 1.6 2 0 0 2 2 2 1 NnrU protein Ribosomal_L6 PF00347.23 KIK68044.1 - 2.3e-26 92.3 5.1 1.6e-14 54.3 2.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Flavi_capsid PF01003.19 KIK68044.1 - 0.051 13.3 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C CBM_4_9 PF02018.17 KIK68044.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CTD_bind PF04818.13 KIK68045.1 - 1.1e-05 26.2 0.0 3.8e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KIK68045.1 - 0.014 15.9 0.2 1 9.9 0.2 2.8 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Herpes_BLRF2 PF05812.12 KIK68045.1 - 0.088 12.9 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Peptidase_M16_M PF16187.5 KIK68045.1 - 0.1 11.9 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 CID_GANP PF16766.5 KIK68045.1 - 0.14 12.3 0.1 0.36 11.0 0.1 1.7 1 0 0 1 1 1 0 Binding region of GANP to ENY2 zf-C2H2_4 PF13894.6 KIK68045.1 - 0.3 12.0 1.2 6.4 7.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger tRNA_synthFbeta PF17759.1 KIK68046.1 - 5.1e-51 173.1 0.0 7.4e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KIK68046.1 - 2.6e-29 101.3 0.0 5.7e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KIK68046.1 - 9.7e-28 97.0 0.0 2.5e-27 95.6 0.0 1.7 1 1 0 1 1 1 1 B3/4 domain B5 PF03484.15 KIK68046.1 - 1.4e-15 57.4 0.0 8.8e-14 51.6 0.0 2.8 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KIK68046.1 - 0.11 11.9 0.0 1.8 8.0 0.0 2.2 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF3531 PF12049.8 KIK68046.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) TRAM_LAG1_CLN8 PF03798.16 KIK68047.1 - 1.2e-35 123.0 26.0 1.2e-35 123.0 26.0 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIK68047.1 - 7.9e-20 70.3 0.4 7.9e-20 70.3 0.4 2.6 3 0 0 3 3 3 1 TRAM1-like protein RNase_T PF00929.24 KIK68048.1 - 1.1e-07 32.5 0.0 2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KIK68048.1 - 0.00026 21.3 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 CHORD PF04968.12 KIK68048.1 - 0.06 14.1 2.7 0.11 13.2 2.7 1.5 1 0 0 1 1 1 0 CHORD DNA_pol_A_exo1 PF01612.20 KIK68048.1 - 0.068 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease zinc_ribbon_5 PF13719.6 KIK68048.1 - 0.18 11.6 1.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain GET2 PF08690.10 KIK68049.1 - 7 6.2 6.0 13 5.4 6.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 MAP7 PF05672.11 KIK68050.1 - 0.81 9.4 38.1 1.6 8.4 38.1 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DnaJ PF00226.31 KIK68051.1 - 5.8e-18 64.8 0.0 9.9e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain RdRP PF05183.12 KIK68052.1 - 1.9e-118 396.7 0.0 2.6e-118 396.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Clat_adaptor_s PF01217.20 KIK68053.1 - 8e-57 191.2 1.7 9.3e-57 190.9 1.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HSF_DNA-bind PF00447.17 KIK68054.1 - 1e-29 103.0 1.0 1.7e-29 102.3 1.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Arrestin_C PF02752.22 KIK68055.1 - 2.7e-05 24.6 0.0 0.00047 20.6 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KIK68055.1 - 0.0041 16.8 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KIK68055.1 - 0.021 14.9 0.0 0.064 13.3 0.0 1.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Myc-LZ PF02344.15 KIK68055.1 - 0.89 9.7 3.4 16 5.7 0.1 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain DUF382 PF04037.13 KIK68056.1 - 2.1e-59 199.2 0.4 2.1e-59 199.2 0.4 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 KIK68056.1 - 1.9e-17 62.9 4.6 3.9e-17 61.8 4.6 1.6 1 0 0 1 1 1 1 PSP Gln-synt_C PF00120.24 KIK68057.1 - 8.9e-18 64.4 0.0 1.1e-15 57.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KIK68057.1 - 1.5e-11 43.9 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Dcc1 PF09724.9 KIK68058.1 - 1.6e-52 178.9 0.0 1.9e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Iso_dh PF00180.20 KIK68060.1 - 3.1e-79 266.7 0.0 3.5e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Amidohydro_2 PF04909.14 KIK68062.1 - 8.4e-28 98.0 0.0 1e-27 97.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.25 KIK68063.1 - 2.6e-40 138.0 0.0 3.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK68063.1 - 1.4e-27 96.7 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK68063.1 - 2.8e-11 43.7 0.0 6.1e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIK68063.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KIK68063.1 - 0.059 12.8 0.0 0.44 10.0 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transket_pyr PF02779.24 KIK68064.1 - 3.4e-46 157.2 0.0 5.9e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIK68064.1 - 1.7e-42 144.2 0.5 3.5e-42 143.2 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KIK68064.1 - 0.0022 18.3 0.0 0.0058 16.9 0.0 1.8 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Tim17 PF02466.19 KIK68064.1 - 0.12 12.8 0.2 0.43 11.0 0.1 1.9 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Histidinol_dh PF00815.20 KIK68065.1 - 1e-165 551.8 0.6 1.4e-165 551.3 0.6 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KIK68065.1 - 8.4e-24 83.2 0.2 1.7e-23 82.2 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KIK68065.1 - 8e-11 42.2 0.0 2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Toprim_2 PF13155.6 KIK68065.1 - 0.0072 16.7 0.0 2.9 8.4 0.0 2.7 1 1 1 2 2 2 2 Toprim-like CPSase_L_D2 PF02786.17 KIK68067.1 - 5.1e-72 241.8 0.0 8.9e-72 241.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIK68067.1 - 2e-47 160.3 0.3 7.9e-47 158.4 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK68067.1 - 3.9e-31 107.3 0.0 4.7e-29 100.6 0.0 2.5 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIK68067.1 - 6.6e-17 61.1 5.2 1.4e-16 60.1 5.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KIK68067.1 - 7.2e-09 35.4 0.1 4.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KIK68067.1 - 6.3e-08 32.3 0.2 9.3e-05 22.2 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KIK68067.1 - 1.5e-07 31.2 0.1 3.6e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GCV_H PF01597.19 KIK68067.1 - 0.00031 20.6 0.3 0.00064 19.6 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 KIK68067.1 - 0.0011 18.2 0.7 0.46 9.7 0.0 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KIK68067.1 - 0.0018 18.2 1.3 0.0065 16.4 0.7 2.1 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 KIK68067.1 - 0.0033 18.1 0.2 0.81 10.4 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.11 KIK68067.1 - 0.012 15.0 0.6 0.024 14.0 0.6 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_3 PF02655.14 KIK68067.1 - 0.014 15.5 0.0 0.045 13.8 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain TspO_MBR PF03073.15 KIK68068.1 - 7.1e-38 129.7 7.5 8.6e-38 129.4 7.5 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF2603 PF10788.9 KIK68069.1 - 0.087 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) Mito_carr PF00153.27 KIK68070.1 - 3.9e-61 203.0 3.3 3.6e-20 71.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KIK68070.1 - 0.0041 17.5 0.0 0.03 14.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KIK68070.1 - 0.065 13.2 0.2 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KIK68070.1 - 0.086 12.4 0.0 0.086 12.4 0.0 2.6 3 0 0 3 3 3 0 EF hand CK_II_beta PF01214.18 KIK68071.1 - 4.6e-75 251.4 0.0 6.2e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.13 KIK68071.1 - 0.0052 16.9 11.8 0.0072 16.5 11.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein PPP4R2 PF09184.11 KIK68071.1 - 0.028 14.0 6.1 0.044 13.4 6.1 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KIK68071.1 - 0.052 13.3 11.2 0.072 12.8 11.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KIK68071.1 - 0.095 12.1 12.4 0.13 11.7 12.4 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 KIK68071.1 - 0.13 11.3 5.7 0.18 10.8 5.7 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 KIK68071.1 - 0.39 8.9 11.9 0.49 8.5 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 KIK68071.1 - 0.66 9.9 8.4 0.83 9.6 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 KIK68071.1 - 0.91 7.7 8.2 1.3 7.3 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KIK68071.1 - 1.4 6.9 20.8 1.8 6.6 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KIK68071.1 - 2.4 7.4 11.7 3.3 6.9 11.7 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 KIK68071.1 - 5.8 6.2 14.9 9.5 5.5 14.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_L36e PF01158.18 KIK68072.1 - 4e-39 132.8 3.5 4.4e-39 132.6 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 KIK68072.1 - 0.041 13.4 0.1 0.051 13.1 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SNARE_assoc PF09335.11 KIK68073.1 - 2.2e-18 66.9 3.8 4.8e-18 65.8 3.8 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein MFS_1 PF07690.16 KIK68074.1 - 4.3e-16 58.8 37.2 4.3e-16 58.8 37.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.21 KIK68075.1 - 7.4e-84 280.5 0.1 1.2e-83 279.8 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK68075.1 - 6e-35 121.2 0.8 1.3e-34 120.1 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KIK68075.1 - 3.6e-17 62.5 0.3 3.6e-17 62.5 0.3 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KIK68075.1 - 3.7e-16 59.7 0.1 3.4e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 KIK68075.1 - 9.6e-06 25.8 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I LOH1CR12 PF10158.9 KIK68075.1 - 0.18 11.9 2.9 3.7 7.6 0.3 3.2 2 1 1 3 3 3 0 Tumour suppressor protein AAA_23 PF13476.6 KIK68075.1 - 1.6 9.2 6.6 12 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain CRCB PF02537.15 KIK68076.1 - 1.4e-31 108.7 15.3 6.1e-18 64.9 5.0 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Clathrin-link PF09268.10 KIK68076.1 - 0.19 11.1 0.7 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Clathrin, heavy-chain linker HVSL PF09749.9 KIK68077.1 - 3.5e-47 160.9 0.3 4.2e-47 160.6 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KIK68077.1 - 3.8e-05 23.6 0.3 5.7e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIK68077.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase Methyltr_RsmB-F PF01189.17 KIK68078.1 - 6.5e-40 136.9 0.0 9.7e-39 133.1 0.0 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF2431 PF10354.9 KIK68078.1 - 0.0047 17.2 0.0 0.0086 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FtsJ PF01728.19 KIK68078.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase VID27 PF08553.10 KIK68080.1 - 2.4e-166 553.2 0.6 3.8e-166 552.5 0.6 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KIK68080.1 - 3e-56 190.0 0.2 3e-56 190.0 0.2 3.2 3 0 0 3 3 3 2 VID27 N-terminal region VID27_PH PF17747.1 KIK68080.1 - 2.3e-20 72.9 1.3 1.1e-19 70.8 1.8 1.9 2 0 0 2 2 2 1 VID27 PH-like domain MTBP_N PF14918.6 KIK68080.1 - 0.074 12.5 3.2 0.052 13.0 1.5 1.5 2 0 0 2 2 2 0 MDM2-binding DNA_pol_phi PF04931.13 KIK68080.1 - 1.9 6.5 13.7 3.3 5.7 13.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Rpr2 PF04032.16 KIK68082.1 - 0.0025 18.1 0.9 0.0025 18.1 0.9 2.2 1 1 1 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain BTB_2 PF02214.22 KIK68083.1 - 0.016 15.5 0.1 0.12 12.8 0.0 2.4 2 1 0 2 2 2 0 BTB/POZ domain ADH_zinc_N PF00107.26 KIK68085.1 - 4.7e-24 84.8 0.1 7e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK68085.1 - 8.9e-15 54.5 0.0 2.5e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIK68085.1 - 2.8e-05 25.2 0.0 4.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3732 PF12532.8 KIK68086.1 - 0.046 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) RRM_1 PF00076.22 KIK68087.1 - 4.3e-15 55.3 0.1 6.1e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L5e PF17144.4 KIK68088.1 - 1.7e-81 272.0 0.0 2.8e-81 271.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KIK68088.1 - 1.6e-34 118.7 1.2 1.6e-34 118.7 1.2 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region K_oxygenase PF13434.6 KIK68088.1 - 0.056 12.6 0.2 0.091 11.9 0.2 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MtrA PF04208.14 KIK68088.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Med17 PF10156.9 KIK68089.1 - 4.7e-37 127.8 0.0 5.9e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.18 KIK68090.1 - 1.5e-18 66.8 0.1 2.5e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK68090.1 - 3e-05 24.0 10.1 5.1e-05 23.3 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPK_catalytic PF04263.16 KIK68091.1 - 2.2e-38 131.0 0.0 2.9e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KIK68091.1 - 6.5e-19 67.4 0.3 9.6e-19 66.9 0.3 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain GPI-anchored PF10342.9 KIK68092.1 - 5.8e-13 49.4 0.7 5.8e-13 49.4 0.7 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KAR9 PF08580.10 KIK68092.1 - 6.8 5.1 6.6 7.5 5.0 6.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Snf7 PF03357.21 KIK68093.1 - 2.4e-29 102.1 20.0 2.4e-29 102.1 20.0 1.3 1 1 0 1 1 1 1 Snf7 Atg14 PF10186.9 KIK68093.1 - 1.3 8.0 8.3 2 7.4 8.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LUC7 PF03194.15 KIK68093.1 - 3.7 7.1 14.1 21 4.7 14.1 2.0 1 1 0 1 1 1 0 LUC7 N_terminus Iso_dh PF00180.20 KIK68094.1 - 2e-100 336.4 0.0 2.4e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.19 KIK68095.1 - 6.4e-104 347.8 0.0 1.3e-103 346.7 0.0 1.6 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KIK68095.1 - 3.9e-26 91.2 0.2 1.1e-25 89.7 0.2 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KIK68095.1 - 8.5e-25 86.6 0.0 1.8e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 KIK68095.1 - 0.00016 21.5 0.0 0.00063 19.7 0.0 2.1 1 1 0 1 1 1 1 S1 domain CSD2 PF17876.1 KIK68095.1 - 0.0002 21.4 0.0 0.087 13.0 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KIK68095.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain WH2 PF02205.20 KIK68096.1 - 1.6e-07 30.9 0.8 5.1e-07 29.3 0.4 2.1 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.20 KIK68097.1 - 2.3e-56 188.1 2.2 2.7e-29 101.2 0.1 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KIK68097.1 - 4e-38 131.2 0.2 1.4e-29 103.3 0.1 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIK68097.1 - 7.5e-09 35.7 0.7 0.001 19.2 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KIK68097.1 - 1.5e-07 31.8 1.9 0.011 16.2 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK68097.1 - 4.9e-06 26.8 0.3 0.28 11.5 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KIK68097.1 - 5.3e-05 23.1 0.4 0.044 13.7 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KIK68097.1 - 6e-05 22.8 0.8 0.76 9.5 0.0 3.3 3 0 0 3 3 3 2 Redoxin OST3_OST6 PF04756.13 KIK68097.1 - 0.0003 20.3 1.8 0.67 9.3 0.0 3.2 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KIK68097.1 - 0.00047 19.3 0.2 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_4 PF13462.6 KIK68097.1 - 0.0096 16.1 0.6 3.1 7.9 0.2 3.2 2 1 1 3 3 3 1 Thioredoxin Asp PF00026.23 KIK68098.1 - 2.4e-110 368.9 0.1 2.7e-110 368.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK68098.1 - 1e-15 58.4 0.6 1.8e-13 51.1 0.6 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK68098.1 - 0.00019 22.0 0.0 0.086 13.5 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KIK68098.1 - 0.00059 19.6 0.0 0.0082 15.9 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KIK68098.1 - 0.00066 20.2 0.0 1.2 9.8 0.0 3.2 2 1 1 3 3 3 2 gag-polyprotein putative aspartyl protease FAT PF02259.23 KIK68099.1 - 3.9e-69 233.5 1.5 1.1e-68 232.0 1.5 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KIK68099.1 - 6.9e-19 68.6 0.0 1.6e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_2 PF07719.17 KIK68099.1 - 0.052 13.7 0.7 22 5.5 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK68099.1 - 4.9 8.2 8.5 7.9 7.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KIK68100.1 - 2.7e-36 125.1 0.0 2.7e-33 115.2 0.0 3.4 3 1 0 3 3 3 1 Aminotransferase class-III AAA_26 PF13500.6 KIK68100.1 - 1.8e-17 63.8 0.0 2.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIK68100.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TaqI_C PF12950.7 KIK68100.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain GCP_N_terminal PF17681.1 KIK68101.1 - 1e-96 324.2 0.0 1.9e-96 323.3 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIK68101.1 - 7e-91 304.9 0.2 1.5e-90 303.8 0.2 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Bromodomain PF00439.25 KIK68102.1 - 8.9e-23 80.2 0.7 2.3e-22 78.9 0.2 1.9 2 1 0 2 2 2 1 Bromodomain F-box-like PF12937.7 KIK68103.1 - 0.0085 16.0 0.0 0.0085 16.0 0.0 2.4 2 1 0 2 2 2 1 F-box-like MIase PF02426.16 KIK68103.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Muconolactone delta-isomerase Pox_E6 PF04656.12 KIK68103.1 - 0.14 10.5 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Pox virus E6 protein LRR_6 PF13516.6 KIK68104.1 - 0.0002 21.1 18.6 2.7 8.3 0.2 6.8 8 0 0 8 8 8 4 Leucine Rich repeat SRP-alpha_N PF04086.13 KIK68104.1 - 4.1 7.2 10.9 6.2 6.7 10.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CTNNBL PF08216.11 KIK68105.1 - 8.8e-33 112.6 0.4 2.4e-32 111.2 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear UTP15_C PF09384.10 KIK68106.1 - 1.1e-46 158.2 0.1 1.7e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KIK68106.1 - 9.3e-22 76.9 3.0 0.00036 21.3 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68106.1 - 2.6e-09 37.2 0.0 0.0071 16.6 0.0 4.3 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TCTP PF00838.17 KIK68107.1 - 5.2e-76 254.6 0.8 5.8e-76 254.4 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein COX16 PF14138.6 KIK68108.1 - 9.3e-31 106.2 0.1 1.1e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Adenylsucc_synt PF00709.21 KIK68109.1 - 1.7e-173 577.3 0.0 2e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase TMEM52 PF14979.6 KIK68110.1 - 0.52 10.2 2.2 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Transmembrane 52 PIG-P PF08510.12 KIK68110.1 - 6.8 6.6 6.2 1.5 8.8 2.6 1.8 2 0 0 2 2 2 0 PIG-P WD40 PF00400.32 KIK68111.1 - 2e-09 37.9 0.8 1.5 9.8 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.25 KIK68112.1 - 3.6e-75 252.7 0.0 5.1e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68112.1 - 9.9e-39 133.2 0.0 1.5e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK68112.1 - 3.5e-06 26.5 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK68112.1 - 9.5e-05 21.5 3.3 0.0023 17.0 0.1 2.8 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KIK68112.1 - 0.0035 16.7 0.2 0.008 15.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK68112.1 - 0.046 12.5 0.0 0.046 12.5 0.0 2.8 2 1 0 2 2 2 0 Fungal protein kinase DEAD PF00270.29 KIK68114.1 - 6.5e-42 143.3 0.0 1.3e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KIK68114.1 - 5.5e-22 77.8 0.2 1.4e-21 76.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KIK68114.1 - 2.8e-19 69.5 0.0 1.2e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK68114.1 - 5.9e-05 23.1 0.2 0.00031 20.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Folliculin PF11704.8 KIK68114.1 - 0.018 15.0 2.1 0.039 13.8 2.1 1.6 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport AAA_22 PF13401.6 KIK68114.1 - 0.089 13.1 0.2 0.59 10.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 KIK68115.1 - 2.5e-11 43.7 5.1 2.5e-11 43.7 5.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIK68115.1 - 3.8e-10 39.9 4.3 3.8e-10 39.9 4.3 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIK68115.1 - 4.2e-08 33.1 2.6 4.2e-08 33.1 2.6 2.5 2 2 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK68115.1 - 3.4e-07 30.0 6.4 3.4e-07 30.0 6.4 2.5 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK68115.1 - 1.8e-06 27.7 4.5 1.8e-06 27.7 4.5 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KIK68115.1 - 2.3e-06 27.8 4.7 5.3e-06 26.6 2.0 2.5 2 0 0 2 2 2 1 zinc-ribbon zf-RING_5 PF14634.6 KIK68115.1 - 9.5e-06 25.5 3.4 9.5e-06 25.5 3.4 2.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIK68115.1 - 1e-05 25.5 0.7 2.1e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KIK68115.1 - 0.00018 21.2 5.1 0.00018 21.2 5.1 2.1 2 1 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KIK68115.1 - 0.0011 18.8 3.4 0.0011 18.8 3.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK68115.1 - 0.005 16.7 6.5 0.005 16.7 6.5 1.9 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KIK68115.1 - 0.017 15.3 4.2 0.2 11.9 4.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.7 KIK68115.1 - 0.2 11.7 8.8 1.7 8.7 0.5 3.1 2 1 1 3 3 3 0 Double zinc ribbon PHD PF00628.29 KIK68115.1 - 0.57 10.1 11.2 0.09 12.7 1.7 2.8 3 1 0 3 3 3 0 PHD-finger Prok-RING_1 PF14446.6 KIK68115.1 - 2.5 8.1 14.0 0.1 12.5 3.5 3.1 2 2 2 4 4 4 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KIK68115.1 - 3.3 7.4 9.7 0.34 10.6 3.5 2.4 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 KIK68116.1 - 6e-66 222.5 0.2 7.9e-45 153.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68116.1 - 6.9e-30 104.2 0.2 8.2e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK68116.1 - 3.2e-07 29.6 0.1 4.8e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK68116.1 - 1.7e-05 24.3 0.2 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK68116.1 - 0.00057 19.3 0.3 0.0049 16.2 0.1 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIK68116.1 - 0.00082 19.4 0.2 0.025 14.5 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KIK68116.1 - 0.0058 17.3 0.6 0.016 15.9 0.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KIK68116.1 - 0.018 13.9 0.1 0.042 12.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KIK68116.1 - 0.027 13.5 0.1 0.055 12.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KIK68116.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KIK68116.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DPBB_1 PF03330.18 KIK68117.1 - 6e-07 29.7 0.1 9.8e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIK68117.1 - 0.025 14.4 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Barwin family PhoLip_ATPase_C PF16212.5 KIK68118.1 - 4.9e-72 242.7 30.1 8.8e-72 241.8 30.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK68118.1 - 1.6e-18 66.1 2.5 4.6e-18 64.7 2.5 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIK68118.1 - 2e-13 51.1 0.2 1.5e-07 31.9 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK68118.1 - 4.9e-11 42.6 0.0 2.3e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK68118.1 - 2.6e-05 24.1 0.3 0.0024 17.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIK68118.1 - 0.0005 19.6 0.9 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Isochorismatase PF00857.20 KIK68119.1 - 6.9e-23 81.7 0.0 4.5e-22 79.1 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family ADK_lid PF05191.14 KIK68121.1 - 0.019 14.9 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid Oxysterol_BP PF01237.18 KIK68122.1 - 6.6e-55 186.5 0.1 3e-52 177.7 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein BCDHK_Adom3 PF10436.9 KIK68123.1 - 4.1e-41 140.5 0.0 5.8e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIK68123.1 - 7.2e-08 32.9 0.0 2.8e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK68123.1 - 0.071 12.9 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med20 PF08612.11 KIK68124.1 - 3.7e-08 33.0 0.0 1.5e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.6 KIK68125.1 - 5.5e-21 75.0 0.0 8.1e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KIK68125.1 - 1.5e-15 58.0 0.0 3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK68125.1 - 4.5e-05 23.9 0.0 9.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK68125.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK68125.1 - 0.036 14.0 0.0 0.055 13.4 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KIK68125.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KIK68125.1 - 0.065 13.2 0.2 1.5 8.7 0.2 2.5 1 1 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KIK68125.1 - 0.16 11.2 0.0 0.49 9.6 0.0 2.0 1 1 0 1 1 1 0 KAP family P-loop domain Peptidase_A17 PF05380.13 KIK68126.1 - 0.073 13.1 0.1 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Pao retrotransposon peptidase SKG6 PF08693.10 KIK68126.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3759 PF12585.8 KIK68127.1 - 7e-38 128.6 6.3 8.1e-38 128.3 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) TetR_C_31 PF17940.1 KIK68127.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3336 PF11815.8 KIK68128.1 - 5e-52 175.3 0.7 8.5e-52 174.5 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KIK68128.1 - 5.6e-18 65.9 0.0 1.5e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase TadE PF07811.12 KIK68128.1 - 0.11 12.8 3.8 0.23 11.8 3.8 1.5 1 0 0 1 1 1 0 TadE-like protein Hydrolase_4 PF12146.8 KIK68128.1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PUB PF09409.10 KIK68129.1 - 2.4e-09 37.0 0.2 6.3e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 PUB domain Caudo_TAP PF02413.17 KIK68129.1 - 0.026 14.7 3.2 0.068 13.3 3.2 1.8 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK eIF3_N PF09440.10 KIK68129.1 - 0.23 11.9 5.0 0.51 10.8 5.0 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain MSC PF09402.10 KIK68129.1 - 0.28 10.6 5.3 0.39 10.1 5.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain FKS1_dom1 PF14288.6 KIK68129.1 - 0.29 11.5 1.4 0.53 10.6 0.1 2.0 1 1 1 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1685 PF07939.11 KIK68130.1 - 0.041 13.6 0.2 4 7.3 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1685) PCI PF01399.27 KIK68131.1 - 3.4e-11 43.6 0.0 4.8e-10 39.9 0.0 2.7 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.9 KIK68131.1 - 0.0057 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 MarR_2 PF12802.7 KIK68131.1 - 0.018 14.9 0.5 10 6.1 0.1 3.2 3 0 0 3 3 3 0 MarR family MarR PF01047.22 KIK68131.1 - 0.066 13.2 0.2 8.6 6.4 0.0 2.8 3 0 0 3 3 3 0 MarR family TPR_7 PF13176.6 KIK68131.1 - 0.18 11.9 0.4 3.5 7.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1365 PF07103.11 KIK68132.1 - 1.9e-55 188.2 0.0 3e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF3818 PF12825.7 KIK68133.1 - 1.1e-134 448.8 0.2 1.5e-134 448.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KIK68133.1 - 2.9e-31 108.2 0.1 6.2e-31 107.1 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KIK68133.1 - 9.6e-14 51.3 0.0 3.5e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 PX domain SDA1 PF05285.12 KIK68133.1 - 0.0043 16.5 2.5 0.0091 15.5 2.5 1.5 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 KIK68133.1 - 0.051 13.0 7.3 0.12 11.7 7.3 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 KIK68133.1 - 0.26 9.5 7.7 0.49 8.5 7.7 1.4 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 KIK68133.1 - 0.27 10.8 2.1 0.51 9.8 2.1 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sigma70_ner PF04546.13 KIK68133.1 - 0.88 9.4 13.4 0.72 9.7 9.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 KIK68133.1 - 3 6.0 6.6 4.7 5.4 6.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KIK68133.1 - 5.1 5.1 14.3 14 3.6 14.3 1.6 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L7Ae PF01248.26 KIK68134.1 - 1.2e-24 85.9 1.3 2.3e-24 85.0 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FTA4 PF13093.6 KIK68134.1 - 0.022 14.6 0.1 0.026 14.4 0.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TLE_N PF03920.15 KIK68135.1 - 0.15 12.2 2.2 0.3 11.2 0.3 2.5 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain LsmAD PF06741.13 KIK68135.1 - 8.6 7.0 13.3 1 10.0 2.7 3.8 3 0 0 3 3 3 0 LsmAD domain RasGAP_C PF03836.15 KIK68135.1 - 9.4 6.4 16.0 0.33 11.1 1.5 3.6 3 1 1 4 4 4 0 RasGAP C-terminus Lectin_N PF03954.14 KIK68135.1 - 9.4 6.0 7.7 2.4 7.9 1.0 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain AMPKBI PF04739.15 KIK68136.1 - 3.5e-21 75.2 1.3 6e-20 71.3 1.3 2.6 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KIK68136.1 - 1.2e-20 73.5 0.6 2.6e-20 72.4 0.2 1.8 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Arm_APC_u3 PF16629.5 KIK68136.1 - 0.00075 19.2 1.5 0.00076 19.2 0.2 1.6 2 0 0 2 2 2 1 Armadillo-associated region on APC DUF3915 PF13054.6 KIK68136.1 - 0.15 12.1 0.6 0.27 11.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RFX_DNA_binding PF02257.15 KIK68137.1 - 6.7e-28 97.1 0.1 1.3e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain NuDC PF16273.5 KIK68137.1 - 0.045 14.3 1.9 0.099 13.2 1.9 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain SpoIIP PF07454.11 KIK68139.1 - 0.027 13.9 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AMP-binding PF00501.28 KIK68140.1 - 6.8e-43 146.8 0.0 9.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIK68140.1 - 7.2e-06 25.8 0.8 1.5e-05 24.8 0.8 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIK68140.1 - 0.00042 21.2 0.0 0.00081 20.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MASE5 PF17178.4 KIK68141.1 - 0.022 14.6 1.6 0.022 14.6 1.6 1.5 2 0 0 2 2 2 0 Membrane-associated sensor DUF420 PF04238.12 KIK68141.1 - 0.028 14.7 5.1 0.035 14.4 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF420) MIG-14_Wnt-bd PF06664.12 KIK68141.1 - 0.03 13.5 7.3 0.073 12.3 7.3 1.6 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Phlebovirus_NSM PF07246.11 KIK68141.1 - 0.048 13.0 0.1 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2079 PF09852.9 KIK68141.1 - 0.051 12.4 4.8 0.067 12.0 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Ac76 PF05814.11 KIK68141.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Orf76 (Ac76) RCR PF12273.8 KIK68141.1 - 2.3 8.9 6.2 0.29 11.8 1.6 2.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1761 PF08570.10 KIK68141.1 - 2.6 8.3 0.0 2.6 8.3 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) DUF4131 PF13567.6 KIK68141.1 - 7 6.3 10.0 8.1 6.1 3.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) GPI2 PF06432.11 KIK68142.1 - 0.67 9.3 6.3 0.85 9.0 6.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase UQ_con PF00179.26 KIK68144.1 - 6.6e-39 132.8 0.1 7.8e-39 132.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK68144.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Uteroglobin PF01099.17 KIK68144.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Uteroglobin family FmiP_Thoc5 PF09766.9 KIK68145.1 - 6.2e-39 134.3 12.5 7.4e-39 134.1 12.5 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 GCIP PF13324.6 KIK68145.1 - 0.0036 16.9 3.9 0.058 13.0 0.9 2.2 2 0 0 2 2 2 2 Grap2 and cyclin-D-interacting T3SSipB PF16535.5 KIK68145.1 - 0.027 14.9 0.5 0.027 14.9 0.5 2.6 1 1 1 3 3 3 0 Type III cell invasion protein SipB SKA2 PF16740.5 KIK68145.1 - 0.25 11.1 11.0 2.5 7.9 0.7 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 CREPT PF16566.5 KIK68145.1 - 0.76 10.0 10.8 0.095 12.9 3.9 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Mod_r PF07200.13 KIK68145.1 - 1.2 9.3 15.1 0.31 11.2 6.3 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein G6PD_C PF02781.16 KIK68146.1 - 3.1e-112 374.5 0.0 4.4e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIK68146.1 - 2.6e-60 204.1 0.0 3.9e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Prenyltrans PF00432.21 KIK68147.1 - 1.9e-57 190.6 4.9 1.3e-10 40.8 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KIK68147.1 - 0.00039 19.6 0.0 0.041 13.0 0.0 3.3 2 1 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIK68147.1 - 0.019 14.1 0.0 0.053 12.6 0.0 1.8 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 KIK68147.1 - 0.19 10.7 0.0 8.3 5.3 0.0 3.1 2 1 2 4 4 4 0 A-macroglobulin TED domain LON_substr_bdg PF02190.16 KIK68148.1 - 1.5e-19 70.7 0.0 1.3e-18 67.7 0.0 2.2 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KIK68148.1 - 1.7e-14 53.3 24.7 3.8e-12 45.8 11.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK68148.1 - 9e-11 41.8 26.4 3.1e-05 24.1 6.1 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIK68148.1 - 6.8e-10 38.7 26.9 1.6e-07 31.1 11.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK68148.1 - 1.6e-09 37.4 19.1 4.8e-08 32.7 6.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK68148.1 - 4.9e-09 36.1 28.7 2.9e-06 27.2 12.2 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KIK68148.1 - 1.1e-08 35.2 24.2 5.5e-07 29.8 12.0 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KIK68148.1 - 8.1e-07 28.9 10.5 8.1e-07 28.9 10.5 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 KIK68148.1 - 6.3e-06 26.2 4.3 6.3e-06 26.2 4.3 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KIK68148.1 - 4.5e-05 23.2 8.2 4.5e-05 23.2 8.2 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIK68148.1 - 0.0015 18.4 13.5 0.0068 16.3 4.7 2.3 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KIK68148.1 - 0.0023 17.7 2.2 0.0023 17.7 2.2 2.9 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIK68148.1 - 0.0025 18.1 7.1 0.0025 18.1 7.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain HNF-1_N PF04814.13 KIK68148.1 - 0.025 15.2 5.5 1.7 9.2 0.5 2.4 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus zf-ANAPC11 PF12861.7 KIK68148.1 - 0.06 13.4 0.9 0.21 11.7 0.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.21 KIK68148.1 - 4.4 7.6 9.6 4 7.7 1.7 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 KIK68150.1 - 3.1e-58 197.2 0.0 6.6e-58 196.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68150.1 - 1.8e-29 102.8 0.0 6.6e-29 101.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK68150.1 - 3.3e-05 22.9 0.0 5.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK68150.1 - 0.00028 20.3 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK68150.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK68150.1 - 0.22 10.4 0.0 0.45 9.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIK68150.1 - 0.23 11.0 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CPDase PF07823.11 KIK68151.1 - 5.8e-13 49.0 0.3 6.6e-12 45.5 0.3 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KIK68151.1 - 1.4e-05 25.1 0.0 6.2e-05 22.9 0.0 1.7 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIK68151.1 - 0.052 13.7 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase HPIP_like PF18524.1 KIK68152.1 - 0.027 14.2 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 High potential iron-sulfur protein like DUF1682 PF07946.14 KIK68153.1 - 6.9e-91 304.8 3.0 7.9e-91 304.6 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Atrophin-1 PF03154.15 KIK68153.1 - 0.0053 15.1 4.1 0.0063 14.9 4.1 1.1 1 0 0 1 1 1 1 Atrophin-1 family Cupin_8 PF13621.6 KIK68155.1 - 2.4e-53 181.4 0.0 3.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KIK68155.1 - 0.0047 17.3 0.0 0.0098 16.3 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase AAA PF00004.29 KIK68157.1 - 0.00073 20.0 0.0 0.019 15.4 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK68157.1 - 0.0043 17.5 0.0 0.019 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KIK68157.1 - 0.014 15.3 0.2 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain T2SSE PF00437.20 KIK68157.1 - 0.051 12.6 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PBP1_TM PF14812.6 KIK68157.1 - 0.11 12.9 5.4 0.25 11.7 5.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HLH PF00010.26 KIK68158.1 - 2.2e-11 43.5 0.7 2.2e-11 43.5 0.7 1.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TFIIF_alpha PF05793.12 KIK68159.1 - 0.011 14.4 57.2 0.033 12.8 0.0 4.1 2 2 2 4 4 4 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Polysacc_deac_1 PF01522.21 KIK68160.1 - 3.1e-22 78.8 0.0 7.1e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TMEM154 PF15102.6 KIK68160.1 - 0.81 9.6 6.7 1.5 8.7 6.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family MGC-24 PF05283.11 KIK68160.1 - 2.7 8.4 9.5 6.3 7.2 9.5 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 KIK68161.1 - 2e-69 233.9 0.0 3.1e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68161.1 - 3.1e-46 157.7 0.0 7.1e-46 156.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK68161.1 - 0.0003 19.7 0.0 0.0013 17.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIK68161.1 - 0.00034 20.0 0.0 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 KIK68161.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Ribosomal_L29 PF00831.23 KIK68162.1 - 6.1e-20 70.9 1.8 6.1e-20 70.9 1.8 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 KIK68162.1 - 0.011 15.8 1.9 0.011 15.8 1.9 1.9 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Taeniidae_ag PF05596.11 KIK68162.1 - 0.26 11.3 0.4 0.26 11.3 0.4 2.7 3 0 0 3 3 3 0 Taeniidae antigen RPW8 PF05659.11 KIK68164.1 - 0.012 15.3 0.7 0.43 10.3 0.0 2.4 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TAF4 PF05236.14 KIK68164.1 - 0.023 14.4 5.7 0.036 13.8 5.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF3042 PF11240.8 KIK68164.1 - 0.12 12.4 0.4 0.25 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) vATP-synt_E PF01991.18 KIK68164.1 - 0.54 9.6 7.1 1 8.7 7.1 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATF7IP_BD PF16788.5 KIK68164.1 - 0.57 10.2 9.0 0.93 9.5 9.0 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain FMO-like PF00743.19 KIK68165.1 - 2.4e-18 65.9 0.0 1.7e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK68165.1 - 2.5e-11 43.3 0.1 3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK68165.1 - 3.7e-11 42.8 0.0 8.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK68165.1 - 7e-10 39.0 0.0 1.3e-08 34.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK68165.1 - 7.3e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK68165.1 - 2.8e-06 27.8 0.5 0.14 12.7 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK68165.1 - 0.00011 22.2 0.1 0.074 13.0 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KIK68165.1 - 0.016 15.7 0.0 0.79 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIK68165.1 - 0.022 14.8 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIK68165.1 - 0.031 13.0 0.7 0.64 8.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KIK68165.1 - 0.043 13.4 2.9 0.39 10.2 0.5 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK68165.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Isochorismatase PF00857.20 KIK68165.1 - 0.15 12.2 0.1 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Isochorismatase family Thi4 PF01946.17 KIK68165.1 - 0.19 10.9 0.2 1 8.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family DSPc PF00782.20 KIK68166.1 - 1.4e-27 96.1 0.0 1.6e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK68166.1 - 0.00017 21.8 0.1 0.00024 21.4 0.1 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIK68166.1 - 0.039 13.5 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glu_syn_central PF04898.14 KIK68166.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain His_biosynth PF00977.21 KIK68167.1 - 1e-35 123.3 0.0 1.3e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein ECR1_N PF14382.6 KIK68168.1 - 1.7e-15 56.5 0.1 3.3e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KIK68168.1 - 4e-13 49.5 0.1 6.5e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KIK68168.1 - 0.037 14.6 0.1 0.76 10.4 0.0 2.4 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 DUF4746 PF15928.5 KIK68169.1 - 0.018 14.5 7.3 0.017 14.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Cwf_Cwc_15 PF04889.12 KIK68169.1 - 0.069 12.9 23.6 0.085 12.6 23.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KIK68169.1 - 0.52 9.8 26.9 0.77 9.3 26.9 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KIK68169.1 - 1.6 8.0 25.7 2.1 7.6 25.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KIK68169.1 - 2.9 6.0 26.5 3.4 5.8 26.5 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KIK68169.1 - 3.3 6.4 7.3 3.5 6.3 7.3 1.0 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 KIK68169.1 - 3.3 7.4 17.5 5 6.9 17.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CAF1A PF12253.8 KIK68169.1 - 3.4 7.9 23.2 7.6 6.8 23.2 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A RNA_pol_3_Rpc31 PF11705.8 KIK68169.1 - 5.3 7.2 27.3 8.6 6.5 27.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF913 PF06025.12 KIK68169.1 - 7.3 5.5 7.7 8.7 5.2 7.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Fe-ADH PF00465.19 KIK68170.1 - 5.6e-91 305.1 0.0 7e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIK68170.1 - 2.9e-11 43.5 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Cyclin_N PF00134.23 KIK68171.1 - 2.2e-13 50.1 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK68171.1 - 0.00075 19.9 0.5 0.0021 18.5 0.0 1.9 2 1 0 2 2 2 1 Cyclin DUF4393 PF14337.6 KIK68171.1 - 0.056 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Asp PF00026.23 KIK68172.1 - 1e-33 117.1 0.6 1e-32 113.8 0.6 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK68172.1 - 0.00027 21.2 3.1 0.0063 16.8 0.2 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal DUF1180 PF06679.12 KIK68172.1 - 0.0031 18.0 0.2 0.0031 18.0 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) DUF3481 PF11980.8 KIK68172.1 - 0.095 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Alpha_GJ PF03229.13 KIK68172.1 - 2.2 8.8 7.0 0.7 10.5 0.4 2.8 2 1 0 2 2 2 0 Alphavirus glycoprotein J CBP_BcsF PF11120.8 KIK68172.1 - 2.3 8.4 5.3 0.71 10.0 2.2 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF PPR_2 PF13041.6 KIK68173.1 - 1.5e-18 66.7 0.1 2e-13 50.3 0.0 4.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 KIK68173.1 - 1.1e-05 25.4 1.9 0.0011 19.1 0.0 4.5 5 1 1 6 6 6 1 PPR repeat PPR_1 PF12854.7 KIK68173.1 - 4.2e-05 23.2 0.1 0.15 11.8 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KIK68173.1 - 0.001 19.1 0.1 0.88 9.7 0.0 2.7 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KIK68173.1 - 0.031 13.6 0.0 2.7 7.3 0.0 3.2 2 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP Utp13 PF08625.11 KIK68173.1 - 0.033 14.1 0.0 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Yos1 PF08571.10 KIK68175.1 - 6e-32 109.7 0.2 6.9e-32 109.6 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Ribosomal_L22 PF00237.19 KIK68177.1 - 1.8e-26 92.4 0.7 1.8e-26 92.4 0.7 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF1351 PF07083.11 KIK68177.1 - 0.0037 17.1 2.1 0.0048 16.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) PUB_1 PF18486.1 KIK68177.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain DUF2149 PF09919.9 KIK68177.1 - 0.07 13.4 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Ribophorin_I PF04597.14 KIK68178.1 - 4.2e-132 441.5 3.9 4.8e-132 441.3 3.9 1.0 1 0 0 1 1 1 1 Ribophorin I DUF2808 PF10989.8 KIK68178.1 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Fimbrial_PilY2 PF14481.6 KIK68178.1 - 0.13 12.0 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 zf-CCHC PF00098.23 KIK68179.1 - 0.00026 20.9 6.2 0.00026 20.9 6.2 5.8 7 0 0 7 7 7 3 Zinc knuckle zf_UBZ PF18439.1 KIK68179.1 - 1.2 8.8 5.1 2.6 7.7 1.4 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CCHC_3 PF13917.6 KIK68179.1 - 2.7 8.0 25.2 3.9 7.5 0.6 4.6 3 2 1 4 4 4 0 Zinc knuckle DZR PF12773.7 KIK68179.1 - 7.4 6.7 22.5 5.6 7.1 5.8 3.6 1 1 1 2 2 2 0 Double zinc ribbon E1-E2_ATPase PF00122.20 KIK68180.1 - 1.4e-45 155.1 1.3 2.8e-45 154.1 0.1 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK68180.1 - 4.5e-33 115.3 0.0 1.2e-32 113.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIK68180.1 - 5.4e-12 46.0 2.5 3.7e-06 27.3 0.6 3.1 2 1 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIK68180.1 - 0.00021 21.1 0.1 0.00036 20.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK68180.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase UxuA PF03786.13 KIK68180.1 - 0.16 10.8 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) His_Phos_2 PF00328.22 KIK68181.1 - 4.5e-85 286.3 0.2 8.9e-85 285.3 0.2 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KIK68181.1 - 5.2e-32 109.8 0.0 1.3e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KIK68181.1 - 6.1e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain UQ_con PF00179.26 KIK68182.1 - 7.2e-15 54.9 0.1 1.1e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 KIK68182.1 - 0.0076 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.22 KIK68182.1 - 0.0097 16.2 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain AMP-binding PF00501.28 KIK68183.1 - 3e-89 299.6 0.0 3.7e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK68183.1 - 1.1e-12 48.8 0.6 2.1e-12 47.8 0.6 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.15 KIK68184.1 - 1.3e-46 158.1 2.6 1.3e-46 158.1 2.6 3.1 4 0 0 4 4 4 1 RasGAP C-terminus RasGAP PF00616.19 KIK68184.1 - 1.3e-42 145.9 1.7 1.3e-42 145.8 0.1 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KIK68184.1 - 5.2e-17 60.0 61.7 0.028 14.2 0.8 12.8 12 0 0 12 12 12 11 IQ calmodulin-binding motif CH PF00307.31 KIK68184.1 - 5.9e-15 55.4 0.1 3.9e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain BLACT_WH PF17778.1 KIK68184.1 - 0.05 13.6 2.1 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain Spc7 PF08317.11 KIK68184.1 - 0.062 12.2 7.8 0.39 9.6 0.7 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Sipho_Gp157 PF05565.11 KIK68184.1 - 0.11 12.5 5.3 0.035 14.1 1.1 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 MFS_1 PF07690.16 KIK68185.1 - 1.2e-29 103.4 16.2 1.2e-29 103.4 16.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FF PF01846.19 KIK68186.1 - 3.4e-36 123.2 21.9 4.5e-10 39.5 0.3 6.3 6 0 0 6 6 6 5 FF domain WW PF00397.26 KIK68186.1 - 1.4e-11 44.2 11.3 8.7e-09 35.3 2.8 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KIK68186.1 - 1.2e-06 29.1 1.4 0.023 15.4 0.0 3.8 2 1 1 3 3 3 2 p190-A and -B Rho GAPs FF domain Chordopox_A13L PF05961.11 KIK68186.1 - 0.2 11.9 0.1 0.7 10.2 0.1 2.0 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TPR_10 PF13374.6 KIK68187.1 - 2.4e-177 570.9 23.9 1.1e-11 44.2 0.0 19.6 20 0 0 20 20 20 19 Tetratricopeptide repeat TPR_12 PF13424.6 KIK68187.1 - 3.4e-125 408.6 56.7 1.9e-13 50.5 0.7 15.1 4 2 14 18 18 18 18 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK68187.1 - 2e-40 139.2 24.9 1.4e-09 37.8 0.2 7.3 1 1 6 7 7 7 7 MalT-like TPR region TPR_7 PF13176.6 KIK68187.1 - 1.4e-22 78.0 34.2 0.0051 16.8 0.1 17.0 17 1 0 17 17 17 6 Tetratricopeptide repeat TPR_4 PF07721.14 KIK68187.1 - 2e-21 74.4 19.8 1.5 9.6 0.5 15.4 18 0 0 18 18 18 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK68187.1 - 4.3e-19 67.5 24.4 1.3 9.6 0.0 15.2 16 0 0 16 16 16 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68187.1 - 1e-11 44.0 46.9 0.93 9.8 0.0 16.3 19 0 0 19 19 19 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68187.1 - 3e-11 43.7 30.2 0.21 12.1 0.0 12.4 9 4 6 15 15 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK68187.1 - 3.2e-10 39.4 39.7 0.026 14.7 0.1 12.5 15 0 0 15 15 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIK68187.1 - 5.3e-07 30.2 19.7 6.7 7.5 0.0 11.2 14 1 0 14 14 13 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK68187.1 - 7e-06 25.6 50.6 4.2 7.4 0.2 15.8 18 0 0 18 18 18 3 Tetratricopeptide repeat Meckelin PF09773.9 KIK68187.1 - 4.2e-05 21.9 2.8 0.096 10.8 0.1 3.8 2 2 0 3 3 3 2 Meckelin (Transmembrane protein 67) TPR_14 PF13428.6 KIK68187.1 - 0.00011 22.8 27.7 25 6.0 0.0 12.9 14 1 0 15 15 13 0 Tetratricopeptide repeat DHDPS PF00701.22 KIK68187.1 - 0.00015 20.6 5.5 15 4.2 0.0 7.4 4 3 5 9 9 9 0 Dihydrodipicolinate synthetase family zf-ACC PF17848.1 KIK68187.1 - 0.017 15.2 0.9 16 5.7 0.1 3.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Dicer_dimer PF03368.14 KIK68187.1 - 0.036 14.2 5.7 2.8 8.2 0.1 4.9 4 1 1 5 5 5 0 Dicer dimerisation domain Pkinase PF00069.25 KIK68189.1 - 2.3e-09 37.0 0.0 5.4e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68189.1 - 8.7e-05 21.9 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IDO PF01231.18 KIK68194.1 - 7.4e-125 417.1 0.0 1.6e-124 416.0 0.0 1.6 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Fungal_trans PF04082.18 KIK68195.1 - 8.4e-09 34.8 0.1 8.4e-09 34.8 0.1 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK68195.1 - 2.5e-06 27.5 10.4 5.9e-06 26.3 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF4G PF02854.19 KIK68197.1 - 3.4e-45 154.3 0.2 4.3e-45 153.9 0.2 1.1 1 0 0 1 1 1 1 MIF4G domain Pkinase_Tyr PF07714.17 KIK68198.1 - 1.6e-07 30.9 0.0 1.8e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK68198.1 - 0.00076 18.9 0.0 0.00092 18.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KIK68199.1 - 5.6e-46 153.6 24.0 1.2e-12 48.1 1.6 8.8 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 KIK68199.1 - 3.4e-13 49.1 1.8 0.0015 17.2 0.0 4.3 3 1 0 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK68199.1 - 1.2e-11 44.7 2.5 1.7e-06 28.2 0.1 4.8 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KIK68199.1 - 0.0018 18.2 0.1 0.0045 16.9 0.1 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KIK68199.1 - 0.0024 17.8 0.7 2.2 8.1 0.1 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK68199.1 - 0.031 12.8 0.3 0.63 8.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK68199.1 - 0.056 12.4 5.5 2.1 7.2 0.5 3.8 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK68199.1 - 0.082 11.6 0.7 2.7 6.6 0.0 3.0 2 2 1 3 3 3 0 Nup133 N terminal like Ribosomal_L14 PF00238.19 KIK68200.1 - 5.9e-43 145.8 3.9 6.5e-43 145.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Peptidase_M56 PF05569.11 KIK68202.1 - 0.0061 15.8 1.2 0.0092 15.2 0.0 1.9 2 0 0 2 2 2 1 BlaR1 peptidase M56 VbhA PF18495.1 KIK68203.1 - 0.22 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Antitoxin VbhA SPC25 PF06703.11 KIK68206.1 - 0.34 10.7 1.2 0.73 9.6 1.2 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CAP_GLY PF01302.25 KIK68207.1 - 5.5e-07 29.5 0.4 2.2e-05 24.4 0.1 2.8 3 0 0 3 3 3 1 CAP-Gly domain BTB PF00651.31 KIK68207.1 - 6.4e-07 29.6 0.0 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Pro-kuma_activ PF09286.11 KIK68208.1 - 7.8e-30 104.0 1.2 1.2e-29 103.4 0.2 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK68208.1 - 1.2e-05 24.7 0.3 1.8e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KIK68209.1 - 2.8e-37 128.2 0.4 2e-36 125.4 0.2 2.2 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK68209.1 - 0.00019 20.8 0.5 0.00028 20.3 0.5 1.3 1 0 0 1 1 1 1 Subtilase family Polysacc_lyase PF14099.6 KIK68210.1 - 0.00083 19.3 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide lyase Pkinase PF00069.25 KIK68211.1 - 4.8e-16 58.9 0.0 3.3e-10 39.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68211.1 - 0.00015 21.2 0.1 0.026 13.8 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase MatE PF01554.18 KIK68212.1 - 0.0021 17.8 0.2 0.0027 17.4 0.2 1.1 1 0 0 1 1 1 1 MatE ANAPC4_WD40 PF12894.7 KIK68214.1 - 3.5e-18 65.7 2.2 6.7e-07 29.5 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK68214.1 - 1.6e-15 57.2 14.6 7.5e-06 26.6 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 KIK68214.1 - 0.0009 19.2 0.0 0.48 10.3 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 KIK68215.1 - 6e-28 97.8 38.2 8.5e-28 97.3 38.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Maf1 PF09174.10 KIK68215.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Maf1 regulator MFS_1 PF07690.16 KIK68217.1 - 1.1e-22 80.4 37.6 1.6e-22 79.9 37.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK68217.1 - 0.00066 18.2 5.4 0.00098 17.7 5.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Metallophos_2 PF12850.7 KIK68218.1 - 1.4e-14 54.6 0.0 2.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIK68218.1 - 0.0016 18.9 0.1 0.0073 16.8 0.1 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase SOG2 PF10428.9 KIK68219.1 - 0.061 12.5 14.1 0.066 12.4 14.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 5_nucleotid_C PF02872.18 KIK68220.1 - 4.6e-31 108.2 0.3 1.2e-29 103.5 0.3 2.4 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIK68220.1 - 0.0067 16.9 1.7 0.014 15.9 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pro-kuma_activ PF09286.11 KIK68221.1 - 7.4e-37 126.8 0.0 1.7e-36 125.6 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK68221.1 - 0.00024 20.5 0.7 0.00035 20.0 0.7 1.4 1 0 0 1 1 1 1 Subtilase family Methyltransf_32 PF13679.6 KIK68222.1 - 7.3e-18 65.0 0.9 1.6e-16 60.7 0.3 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK68222.1 - 0.028 15.1 0.1 0.12 13.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_28 PF02636.17 KIK68222.1 - 0.042 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 KIK68222.1 - 0.13 12.0 0.1 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 KIK68223.1 - 2.5e-83 280.4 22.0 3e-83 280.2 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK68223.1 - 1.4e-20 73.5 63.2 1.5e-19 70.1 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 KIK68224.1 - 1.5e-117 393.3 0.1 2.1e-117 392.9 0.1 1.1 1 0 0 1 1 1 1 Amidase NAD_synthase PF02540.17 KIK68224.1 - 0.078 12.1 0.4 0.14 11.3 0.4 1.3 1 0 0 1 1 1 0 NAD synthase Transport_MerF PF11431.8 KIK68225.1 - 0.21 11.5 2.1 19 5.3 0.4 2.7 2 0 0 2 2 2 0 Membrane transport protein MerF ECF_trnsprt PF12822.7 KIK68225.1 - 1.7 8.7 9.5 0.78 9.8 1.9 2.4 1 1 1 2 2 2 0 ECF transporter, substrate-specific component TMEM154 PF15102.6 KIK68226.1 - 0.00062 19.7 1.1 0.0012 18.8 1.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family TRP PF06011.12 KIK68226.1 - 0.015 14.0 0.2 0.02 13.6 0.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DAP10 PF07213.11 KIK68226.1 - 0.059 13.3 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein DAG1 PF05454.11 KIK68226.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 KIK68226.1 - 0.11 13.4 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 KIK68226.1 - 0.13 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 KIK68226.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Rifin Ustilago_mating PF05722.12 KIK68226.1 - 7.2 6.0 9.9 12 5.4 9.9 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein UIM PF02809.20 KIK68227.1 - 0.0028 17.4 3.2 0.0073 16.2 3.2 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Syntaxin-6_N PF09177.11 KIK68227.1 - 0.011 16.3 0.0 0.041 14.4 0.0 2.0 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CUE PF02845.16 KIK68227.1 - 0.015 15.0 0.0 0.092 12.5 0.0 2.2 2 0 0 2 2 2 0 CUE domain HTH_8 PF02954.19 KIK68227.1 - 0.06 13.2 2.0 0.29 11.0 0.1 2.7 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family UBA PF00627.31 KIK68227.1 - 0.083 12.8 1.0 0.36 10.8 1.0 2.1 1 1 0 1 1 1 0 UBA/TS-N domain UBA_4 PF14555.6 KIK68227.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF3990 PF13151.6 KIK68228.1 - 2e-10 40.5 0.0 3.1e-10 39.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3990) Sec10 PF07393.11 KIK68229.1 - 2.9e-128 429.3 0.0 3.9e-128 428.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KIK68229.1 - 0.01 15.7 0.4 0.033 14.1 0.0 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK68229.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIK68230.1 - 1.6e-05 24.7 0.0 6e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK68230.1 - 0.0021 17.9 0.1 0.0021 17.9 0.1 3.7 4 0 0 4 4 4 1 F-box domain zf-C4H2 PF10146.9 KIK68232.1 - 0.21 11.9 0.2 0.37 11.1 0.2 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Methyltransf_3 PF01596.17 KIK68233.1 - 6.9e-33 113.6 0.0 8.4e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIK68233.1 - 2.7e-16 60.5 0.0 5.7e-16 59.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK68233.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK68233.1 - 1e-06 29.3 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK68233.1 - 8.2e-06 26.4 0.0 2.1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK68233.1 - 0.00041 20.2 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 KIK68233.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GCD14 PF08704.10 KIK68233.1 - 0.027 14.2 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 KIK68233.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIK68233.1 - 0.035 13.4 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ThiF PF00899.21 KIK68234.1 - 4.5e-42 144.1 0.0 9.6e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KIK68234.1 - 6.4e-06 26.4 0.5 9.5e-05 22.7 0.5 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KIK68234.1 - 0.00027 21.3 0.3 0.0013 19.2 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 KIK68234.1 - 0.019 14.6 0.1 0.065 12.9 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIK68234.1 - 0.021 14.4 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KIK68234.1 - 0.028 14.0 0.4 0.06 12.9 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK68234.1 - 0.037 13.3 0.3 0.057 12.7 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KIK68234.1 - 0.055 13.3 0.3 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK68234.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 KIK68235.1 - 2.3e-18 66.2 0.0 4.9e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK68235.1 - 0.00023 21.2 14.4 0.00041 20.4 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 KIK68236.1 - 6.8e-47 160.4 0.0 9.9e-43 146.7 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 KIK68236.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KIK68236.1 - 0.026 13.2 0.0 0.067 11.9 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Tmemb_18A PF09771.9 KIK68236.1 - 0.089 13.2 0.0 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 188 Glyco_hydro_43 PF04616.14 KIK68238.1 - 2.5e-31 109.1 0.1 3.8e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_6 PF12697.7 KIK68239.1 - 1.6e-12 48.5 0.0 2.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KIK68239.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme EI24 PF07264.11 KIK68240.1 - 3.8e-08 33.8 8.4 6.7e-08 33.0 8.4 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ribosomal_S8 PF00410.19 KIK68241.1 - 8.1e-12 45.2 0.0 3.3e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 Bromo_TP PF07524.13 KIK68243.1 - 1.2e-08 34.8 0.1 2e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 KIK68243.1 - 2.4e-05 24.8 1.3 2.4e-05 24.8 1.3 3.1 2 1 1 3 3 3 2 Transcription factor TFIID complex subunit 8 C-term F-box-like PF12937.7 KIK68244.1 - 8.2e-12 44.8 1.5 3.4e-11 42.8 1.5 2.2 1 0 0 1 1 1 1 F-box-like TIR_3 PF18567.1 KIK68244.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain F-box PF00646.33 KIK68244.1 - 0.72 9.8 8.9 2 8.4 0.9 4.0 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 KIK68245.1 - 5.6e-08 32.5 3.8 4.7e-07 29.6 3.8 2.7 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK68246.1 - 3.9e-09 36.3 2.5 4.1e-09 36.2 0.6 2.2 2 0 0 2 2 2 1 F-box-like MARVEL PF01284.23 KIK68247.1 - 2 8.4 10.5 2.2 8.3 5.6 2.2 2 0 0 2 2 2 0 Membrane-associating domain Yip1 PF04893.17 KIK68249.1 - 2.9e-08 33.6 23.5 1.6e-07 31.2 23.6 1.9 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KIK68249.1 - 0.048 13.2 9.7 0.46 10.0 9.7 2.2 1 1 0 1 1 1 0 YIF1 Stevor PF17410.2 KIK68249.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4743 PF15916.5 KIK68250.1 - 7.1e-09 35.7 0.0 2.1e-07 30.9 0.0 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KIK68250.1 - 7.7e-05 22.7 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peroxidase_2 PF01328.17 KIK68251.1 - 1.7e-48 165.7 0.0 2.3e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NAD_binding_10 PF13460.6 KIK68252.1 - 1.7e-19 70.4 0.0 1.7e-18 67.2 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK68252.1 - 1.9e-06 27.6 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIK68252.1 - 0.00037 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK68252.1 - 0.0022 18.3 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DRTGG PF07085.12 KIK68252.1 - 0.054 13.3 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 DRTGG domain NAD_binding_10 PF13460.6 KIK68254.1 - 1.7e-09 37.8 0.0 0.001 19.0 0.0 3.0 2 1 0 2 2 2 2 NAD(P)H-binding COesterase PF00135.28 KIK68255.1 - 9.4e-90 301.9 0.0 1e-89 301.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK68255.1 - 2.3e-06 27.6 0.2 4.7e-05 23.3 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK68255.1 - 0.1 12.0 0.5 0.17 11.3 0.5 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PQQ PF01011.21 KIK68256.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat MA3 PF02847.17 KIK68257.1 - 1.2e-25 89.7 0.1 3e-25 88.4 0.1 1.8 1 0 0 1 1 1 1 MA3 domain GMP_synt_C PF00958.22 KIK68257.1 - 0.06 13.4 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 GMP synthase C terminal domain Lactamase_B PF00753.27 KIK68258.1 - 1.6e-17 64.2 0.7 5.9e-17 62.3 0.7 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KIK68258.1 - 5.7e-14 51.8 0.0 2.1e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KIK68258.1 - 0.0018 17.8 0.1 0.0032 17.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain OPT PF03169.15 KIK68259.1 - 3.8e-191 636.9 63.7 4.4e-191 636.7 63.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ATP1G1_PLM_MAT8 PF02038.16 KIK68259.1 - 0.1 12.1 0.1 0.1 12.1 0.1 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PARP PF00644.20 KIK68260.1 - 1.3e-11 44.5 0.0 3.7e-08 33.2 0.0 2.7 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Tannase PF07519.11 KIK68261.1 - 4.1e-116 388.7 0.0 4.7e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KIK68261.1 - 0.00049 19.4 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK68261.1 - 0.013 15.1 0.2 0.04 13.6 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1921 PF09081.10 KIK68262.1 - 0.091 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) CRC_subunit PF08624.10 KIK68264.1 - 2.9e-43 147.6 0.0 4e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RRN9 PF10680.9 KIK68265.1 - 0.038 14.3 0.9 0.07 13.4 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Glyco_hydro_18 PF00704.28 KIK68266.1 - 1.2e-14 54.8 1.0 2.2e-14 53.9 1.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase_fungal PF17667.1 KIK68268.1 - 2.7e-43 148.3 0.0 3.9e-29 101.7 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK68268.1 - 4.1e-06 26.9 0.6 0.0041 17.1 0.1 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIK68268.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK68268.1 - 0.009 15.6 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family p450 PF00067.22 KIK68270.1 - 3.1e-74 250.4 0.0 3.5e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Na_H_antiport_3 PF07399.11 KIK68270.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Ph1570 PF09638.10 KIK68270.1 - 0.22 11.4 0.1 0.37 10.6 0.1 1.3 1 0 0 1 1 1 0 Ph1570 protein zf-C3HC4_2 PF13923.6 KIK68271.1 - 1.4e-08 34.4 2.0 1.4e-08 34.4 2.0 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK68271.1 - 3.2e-08 33.3 2.7 3.2e-08 33.3 2.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK68271.1 - 2.8e-07 30.3 4.1 2.8e-07 30.3 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK68271.1 - 6.6e-07 29.3 3.3 6.6e-07 29.3 3.3 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK68271.1 - 4.8e-06 26.4 4.2 4.8e-06 26.4 4.2 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK68271.1 - 2.4e-05 24.4 4.0 2.4e-05 24.4 4.0 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK68271.1 - 3.3e-05 24.1 7.5 3.3e-05 24.1 7.5 2.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 KIK68271.1 - 0.0043 16.9 0.5 0.0043 16.9 0.5 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-UBR PF02207.20 KIK68271.1 - 0.018 15.2 1.0 0.018 15.2 1.0 2.1 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Pellino PF04710.14 KIK68271.1 - 0.16 10.6 0.4 0.26 9.9 0.4 1.2 1 0 0 1 1 1 0 Pellino Prok-RING_4 PF14447.6 KIK68271.1 - 0.38 10.7 16.5 0.65 9.9 8.0 3.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 TPT PF03151.16 KIK68272.1 - 6e-39 134.1 16.4 7.3e-38 130.6 16.4 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK68272.1 - 5.7e-09 36.3 34.0 2.1e-06 27.9 12.3 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIK68272.1 - 9.7e-09 34.8 18.8 3.4e-08 33.1 18.8 1.7 1 1 0 1 1 1 1 UAA transporter family Pyr_redox_3 PF13738.6 KIK68274.1 - 2.6e-19 69.6 0.0 9.2e-17 61.2 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK68274.1 - 3.3e-19 68.7 0.1 1.9e-14 53.0 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK68274.1 - 3.3e-13 49.5 0.0 9.3e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK68274.1 - 6.1e-09 35.5 0.1 1.7e-06 27.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK68274.1 - 0.0016 19.0 0.0 0.86 10.2 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK68274.1 - 0.0018 18.5 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK68274.1 - 0.0042 16.5 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KIK68274.1 - 0.0042 16.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK68274.1 - 0.024 13.8 0.1 0.17 11.0 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KIK68274.1 - 0.036 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KIK68274.1 - 0.044 12.9 0.1 0.4 9.7 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIK68274.1 - 0.046 13.6 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIK68274.1 - 0.14 10.8 0.0 0.37 9.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_18 PF00704.28 KIK68276.1 - 2.7e-13 50.3 1.6 5.2e-13 49.4 1.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 NmrA PF05368.13 KIK68277.1 - 4.3e-29 101.7 0.0 5.5e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK68277.1 - 5.2e-05 23.2 0.0 0.067 13.1 0.0 2.7 3 0 0 3 3 3 2 NAD(P)H-binding PigN PF04987.14 KIK68278.1 - 8.5e-120 400.7 30.4 1.3e-119 400.1 30.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KIK68278.1 - 3.7e-09 36.6 0.0 3.9e-05 23.4 0.2 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIK68278.1 - 8.9e-07 28.6 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KIK68278.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Asp_Glu_race PF01177.22 KIK68280.1 - 9.3e-08 32.2 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DAO PF01266.24 KIK68281.1 - 3.6e-27 95.9 0.1 4.1e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Spc7 PF08317.11 KIK68282.1 - 0.0053 15.7 4.2 0.0095 14.9 4.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein FlaC_arch PF05377.11 KIK68282.1 - 0.0097 16.3 0.3 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Lipoprotein_6 PF01441.19 KIK68282.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.6 1 1 0 1 1 1 0 Lipoprotein ABC_tran_CTD PF16326.5 KIK68282.1 - 0.16 12.2 4.0 4.2 7.7 0.5 3.2 3 1 1 4 4 4 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 KIK68282.1 - 1.5 8.3 7.3 2.1 7.9 7.2 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 KIK68283.1 - 2.5e-64 217.6 0.0 5.6e-64 216.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KIK68283.1 - 1.4e-57 194.6 0.0 4.2e-57 193.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIK68283.1 - 3.7e-11 43.2 0.1 0.0043 16.8 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KIK68283.1 - 3.8e-11 43.5 0.0 6.4e-10 39.5 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK68283.1 - 2.6e-10 40.3 0.0 9.7e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KIK68283.1 - 1.3e-06 28.5 0.0 2.3e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KIK68283.1 - 4.7e-06 26.1 0.0 0.058 12.6 0.0 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KIK68283.1 - 3.4e-05 23.5 0.0 9.8e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KIK68283.1 - 7.2e-05 23.1 0.0 0.0022 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KIK68283.1 - 0.00014 21.6 0.1 0.00087 19.1 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KIK68283.1 - 0.002 17.6 0.0 0.47 9.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 KIK68283.1 - 0.01 16.3 0.0 0.033 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KIK68283.1 - 0.022 14.5 0.1 0.36 10.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIK68283.1 - 0.027 14.9 1.4 0.086 13.3 0.2 2.5 3 1 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 KIK68283.1 - 0.036 13.9 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Helicase DUF4746 PF15928.5 KIK68283.1 - 0.083 12.3 1.5 0.13 11.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_helicase PF00910.22 KIK68283.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KIK68283.1 - 0.14 11.3 0.0 6.8 5.7 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase NmrA PF05368.13 KIK68284.1 - 2.3e-32 112.4 0.0 2.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK68284.1 - 9.1e-11 42.0 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK68284.1 - 0.026 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK68284.1 - 0.037 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ATPase_2 PF01637.18 KIK68285.1 - 6.1e-18 65.6 0.1 1.6e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIK68285.1 - 5.5e-07 30.1 0.9 3.9e-06 27.4 0.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK68285.1 - 0.00041 20.6 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KIK68285.1 - 0.00048 20.6 0.0 0.21 12.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 KIK68285.1 - 0.00062 18.6 0.6 0.0084 14.9 0.0 2.5 2 1 1 3 3 3 1 RNA12 protein ResIII PF04851.15 KIK68285.1 - 0.003 17.6 0.3 0.0069 16.4 0.3 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KIK68285.1 - 0.012 15.9 0.1 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIK68285.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ApbA_C PF08546.11 KIK68286.1 - 2.2e-19 69.9 0.0 1e-16 61.3 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIK68286.1 - 9.4e-16 57.8 0.0 1.5e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA N_formyltrans_C PF18216.1 KIK68286.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain BCS1_N PF08740.11 KIK68287.1 - 3.7e-42 144.4 1.5 3.7e-42 144.4 1.5 3.5 4 0 0 4 4 4 1 BCS1 N terminal AAA PF00004.29 KIK68287.1 - 5.3e-14 52.8 0.0 3.9e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AP3D1 PF06375.11 KIK68287.1 - 1.2e-05 25.6 40.8 0.099 12.9 7.4 3.5 3 0 0 3 3 3 3 AP-3 complex subunit delta-1 Cwf_Cwc_15 PF04889.12 KIK68287.1 - 0.00052 19.8 13.4 0.00052 19.8 13.4 3.7 4 0 0 4 4 4 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KIK68287.1 - 0.0023 17.3 6.9 0.0023 17.3 6.9 3.0 2 2 1 3 3 3 2 BUD22 Viral_helicase1 PF01443.18 KIK68287.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIK68287.1 - 0.0061 17.0 0.2 0.019 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK68287.1 - 0.011 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KIK68287.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rtf2 PF04641.12 KIK68287.1 - 0.17 11.2 39.1 0.81 9.0 8.2 3.3 3 0 0 3 3 3 0 Rtf2 RING-finger Astro_capsid_p PF12226.8 KIK68287.1 - 0.2 10.8 11.1 9.1 5.3 0.0 2.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein GAGA_bind PF06217.12 KIK68287.1 - 0.37 11.0 26.2 0.71 10.1 0.0 3.2 2 1 1 3 3 3 0 GAGA binding protein-like family DDRGK PF09756.9 KIK68287.1 - 0.48 10.0 30.5 0.081 12.5 10.3 4.0 4 0 0 4 4 4 0 DDRGK domain SART-1 PF03343.13 KIK68287.1 - 1.6 7.2 40.4 0.5 8.9 6.9 3.1 3 0 0 3 3 3 0 SART-1 family SSTK-IP PF15836.5 KIK68287.1 - 3.5 7.8 7.9 4.3 7.5 1.4 3.4 3 0 0 3 3 3 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Vfa1 PF08432.10 KIK68287.1 - 6.7 7.0 46.1 3.5 7.9 9.9 3.3 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF4604 PF15377.6 KIK68287.1 - 8.3 6.8 44.7 0.026 15.0 3.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Presenilin PF01080.17 KIK68287.1 - 9.3 4.9 33.5 2.1 7.0 2.0 3.3 3 0 0 3 3 3 0 Presenilin SH3_6 PF12913.7 KIK68288.1 - 0.08 12.5 0.2 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) DUF202 PF02656.15 KIK68289.1 - 9.9e-17 61.2 0.1 9.9e-17 61.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) S_4TM PF18159.1 KIK68289.1 - 0.11 11.7 4.7 0.12 11.7 3.7 1.5 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain 7tm_1 PF00001.21 KIK68289.1 - 0.31 10.3 8.9 0.42 9.9 8.9 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.8 KIK68289.1 - 7.9 6.6 7.9 13 5.9 7.5 1.6 1 1 0 1 1 1 0 Protein of unknown function M20_dimer PF07687.14 KIK68290.1 - 1.7e-09 37.6 0.0 3.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIK68290.1 - 3.2e-07 30.2 0.5 5.2e-07 29.6 0.5 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK68291.1 - 1.7e-07 31.1 0.0 3.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIK68291.1 - 5.4e-06 26.2 0.0 9.7e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1905 PF08922.11 KIK68291.1 - 0.00099 19.1 0.0 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1905) Cyt-b5 PF00173.28 KIK68292.1 - 2.9e-10 40.2 0.2 3.8e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SR-25 PF10500.9 KIK68292.1 - 0.12 11.9 4.8 0.16 11.6 4.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUV3_C PF12513.8 KIK68293.1 - 5.4e-12 45.4 1.0 1.4e-11 44.1 1.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KIK68293.1 - 3.6e-08 33.7 0.0 7.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KIK68293.1 - 0.012 15.4 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 T2SSE PF00437.20 KIK68293.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MRP-S33 PF08293.11 KIK68294.1 - 3.1e-33 113.9 0.1 3.9e-33 113.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MCU PF04678.13 KIK68297.1 - 4.2e-38 131.2 0.0 6.5e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Per1 PF04080.13 KIK68297.1 - 0.044 13.5 0.1 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Per1-like family DUF2721 PF11026.8 KIK68297.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4246 PF14033.6 KIK68298.1 - 9.1e-60 203.0 0.1 4.7e-58 197.4 0.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) ArfGap PF01412.18 KIK68299.1 - 2.7e-39 133.9 0.1 3.9e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 KIK68299.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain F-box-like PF12937.7 KIK68300.1 - 0.0005 19.9 0.6 0.0011 18.8 0.4 1.8 1 1 0 1 1 1 1 F-box-like DUF1242 PF06842.12 KIK68300.1 - 0.027 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) DUF1674 PF07896.12 KIK68301.1 - 1.3e-08 35.1 9.7 4.2e-08 33.6 9.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) ARTD15_N PF18084.1 KIK68301.1 - 0.19 12.0 0.2 0.22 11.8 0.2 1.2 1 0 0 1 1 1 0 ARTD15 N-terminal domain Epimerase PF01370.21 KIK68302.1 - 2.3e-52 177.8 0.0 3.3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK68302.1 - 2.2e-16 60.2 0.0 6.1e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK68302.1 - 2.4e-06 26.9 0.0 0.00024 20.3 0.0 3.1 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KIK68302.1 - 9.7e-05 21.5 0.0 0.00027 20.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIK68302.1 - 0.00018 20.7 0.0 0.00053 19.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain PAPS_reduct PF01507.19 KIK68303.1 - 2.1e-26 93.0 0.0 3.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family S4 PF01479.25 KIK68304.1 - 4.1e-11 42.4 1.3 4.1e-11 42.4 1.3 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KIK68304.1 - 3.1e-06 28.0 0.1 4.8e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KIK68305.1 - 8.2e-45 150.8 3.8 1.2e-44 150.3 3.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.13 KIK68305.1 - 0.1 11.0 0.1 0.12 10.8 0.1 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain Mre11_DNA_bind PF04152.14 KIK68306.1 - 7.5e-50 169.5 0.4 7.5e-50 169.5 0.4 2.8 3 1 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KIK68306.1 - 2.1e-14 54.5 0.7 3.8e-14 53.7 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK68306.1 - 3.9e-05 23.9 0.0 0.0005 20.3 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyoxalase_2 PF12681.7 KIK68306.1 - 0.07 13.1 0.8 0.18 11.7 0.8 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain TPT PF03151.16 KIK68307.1 - 1.9e-13 50.5 24.5 2.2e-13 50.2 24.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK68307.1 - 3.6e-05 23.9 40.4 0.00067 19.8 12.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family SNF2_N PF00176.23 KIK68310.1 - 3.9e-75 252.7 0.1 8.6e-75 251.6 0.1 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK68310.1 - 1.2e-19 70.7 0.0 2.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF5572 PF17733.1 KIK68310.1 - 2.8e-09 36.7 0.2 7.8e-09 35.2 0.2 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) ResIII PF04851.15 KIK68310.1 - 1.7e-07 31.4 0.0 4.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK68310.1 - 0.001 18.3 0.8 0.0019 17.4 0.8 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIK68310.1 - 0.0015 18.3 0.1 0.025 14.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KIK68310.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF1179 PF06678.11 KIK68310.1 - 0.14 12.1 2.1 0.44 10.6 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) DEAD_2 PF06733.15 KIK68310.1 - 0.17 11.5 1.5 1 8.9 0.0 2.7 3 1 2 5 5 5 0 DEAD_2 Secretin_N PF03958.17 KIK68310.1 - 0.21 12.0 1.9 2.4 8.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain EST1_DNA_bind PF10373.9 KIK68311.1 - 3.4e-27 95.7 0.1 2.1e-26 93.1 0.1 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KIK68311.1 - 5.4e-22 78.9 0.0 1.3e-21 77.7 0.0 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_2 PF07719.17 KIK68311.1 - 0.027 14.5 0.2 2.6 8.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CITED PF04487.12 KIK68311.1 - 0.044 13.9 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 CITED SUZ PF12752.7 KIK68313.1 - 1.4e-14 54.6 0.4 1.4e-14 54.6 0.4 2.8 3 1 0 3 3 3 1 SUZ domain SUZ-C PF12901.7 KIK68313.1 - 0.014 15.4 0.1 0.32 11.0 0.0 2.8 3 0 0 3 3 3 0 SUZ-C motif eIF3_subunit PF08597.10 KIK68313.1 - 0.015 15.2 4.5 0.02 14.8 4.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_M20 PF01546.28 KIK68314.1 - 3.7e-34 118.2 0.0 5.8e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK68314.1 - 6.8e-11 42.1 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK68314.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 MFS_1 PF07690.16 KIK68315.1 - 4.5e-42 144.2 30.9 4.4e-39 134.4 19.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK68315.1 - 3.1e-11 42.8 7.4 3.1e-11 42.8 7.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KIK68315.1 - 4.3e-06 25.4 5.0 8.5e-06 24.5 5.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KIK68315.1 - 0.00012 20.6 4.8 0.00022 19.8 4.8 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector BRO1 PF03097.18 KIK68316.1 - 2.4e-117 392.0 0.5 2.4e-117 392.0 0.5 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIK68316.1 - 3e-58 197.5 2.2 4.3e-58 196.9 2.2 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MAP65_ASE1 PF03999.12 KIK68316.1 - 0.0034 16.2 1.5 0.0063 15.3 1.5 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) SRP68 PF16969.5 KIK68316.1 - 0.007 15.4 0.2 0.016 14.2 0.2 1.6 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF1108 PF06531.11 KIK68316.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) DUF543 PF04418.12 KIK68317.1 - 1.4e-23 82.6 0.7 7.9e-23 80.2 0.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF543) NmrA PF05368.13 KIK68318.1 - 9.2e-25 87.6 0.0 1.1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK68318.1 - 1.4e-08 34.9 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF3990 PF13151.6 KIK68319.1 - 1.3e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Exotox-A_cataly PF09009.10 KIK68319.1 - 0.0018 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Exotoxin A catalytic PARP PF00644.20 KIK68319.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain NmrA PF05368.13 KIK68320.1 - 1.2e-28 100.2 0.0 1.5e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK68320.1 - 7.6e-09 35.7 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding cEGF PF12662.7 KIK68321.1 - 0.3 11.0 0.2 0.3 11.0 0.2 4.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like DIOX_N PF14226.6 KIK68322.1 - 9.9e-21 74.7 0.1 2.4e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK68322.1 - 4.7e-14 52.7 0.0 9.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK68323.1 - 6.9e-15 55.8 0.0 1.4e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK68323.1 - 1.2e-14 54.6 0.0 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF5 PF04855.12 KIK68324.1 - 2.1e-66 224.1 0.1 3.3e-66 223.5 0.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KIK68324.1 - 0.34 10.6 4.9 0.76 9.4 4.9 1.7 1 0 0 1 1 1 0 GATA zinc finger TMEM190 PF15431.6 KIK68325.1 - 3.9 7.6 5.2 1.6 8.9 0.1 2.7 2 1 1 3 3 3 0 Transmembrane protein 190 EHN PF06441.12 KIK68327.1 - 2.2e-32 111.6 0.3 4.1e-32 110.8 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK68327.1 - 2.9e-10 40.3 0.0 5.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68327.1 - 5.4e-05 23.9 0.2 0.00015 22.4 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FGF-BP1 PF06473.12 KIK68328.1 - 0.004 17.0 5.3 0.0048 16.8 5.3 1.0 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Spore_GerAC PF05504.11 KIK68328.1 - 0.023 14.9 0.3 0.025 14.8 0.3 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Hydantoinase_A PF01968.18 KIK68328.1 - 0.23 10.7 0.4 0.31 10.2 0.4 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase ATP-synt_B PF00430.18 KIK68328.1 - 0.63 10.1 8.2 0.86 9.7 8.2 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) YtxH PF12732.7 KIK68328.1 - 0.66 10.6 5.3 1 9.9 5.3 1.3 1 0 0 1 1 1 0 YtxH-like protein DUF4724 PF15852.5 KIK68328.1 - 2.1 8.9 6.1 1.9 9.0 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4724) HK97-gp10_like PF04883.12 KIK68329.1 - 0.049 14.6 0.7 0.069 14.1 0.7 1.2 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Fungal_trans PF04082.18 KIK68330.1 - 3.3e-05 23.1 0.0 6.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK68330.1 - 3.4e-05 23.9 12.1 6.3e-05 23.0 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP20 PF00011.21 KIK68331.1 - 1.1e-13 51.2 0.0 7.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK68331.1 - 6.2e-08 32.1 0.1 2.9e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA ALO PF04030.14 KIK68332.1 - 2e-35 122.9 3.1 2.9e-35 122.4 3.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK68332.1 - 3.4e-21 75.4 0.0 4.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain CSTF2_hinge PF14327.6 KIK68333.1 - 5.7e-28 97.2 2.2 5.7e-28 97.2 2.2 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KIK68333.1 - 2.5e-16 59.3 0.0 4.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KIK68333.1 - 1.3e-13 50.3 0.1 3.7e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal tRNA-synt_2b PF00587.25 KIK68334.1 - 3.7e-34 118.2 0.0 7.3e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIK68334.1 - 6e-19 68.0 0.2 1.4e-18 66.8 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KIK68334.1 - 2.3e-13 50.0 0.0 6.5e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KIK68334.1 - 2.3e-12 46.8 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Pkinase PF00069.25 KIK68335.1 - 1.7e-16 60.4 0.0 4.5e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KIK68335.1 - 4.7e-16 58.9 15.4 5.6e-08 33.3 0.6 6.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KIK68335.1 - 4.5e-11 42.0 11.4 0.01 16.0 0.1 5.8 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.17 KIK68335.1 - 1.5e-07 31.0 0.0 4.4e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KIK68335.1 - 7.1e-07 29.5 0.3 0.083 13.3 0.1 4.2 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KIK68335.1 - 0.024 14.7 6.7 40 4.2 0.1 4.5 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Nucleoporin_N PF08801.11 KIK68335.1 - 0.042 12.6 0.5 18 3.9 0.0 3.4 2 1 0 3 3 3 0 Nup133 N terminal like HEAT_EZ PF13513.6 KIK68335.1 - 1 9.9 3.3 1.2e+02 3.4 0.1 3.8 3 0 0 3 3 3 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KIK68335.1 - 1.2 9.5 4.6 10 6.5 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DIOX_N PF14226.6 KIK68336.1 - 8.6e-15 55.5 0.0 1.4e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK68336.1 - 8.1e-13 48.7 0.1 4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Myb_DNA-bind_6 PF13921.6 KIK68338.1 - 5.9e-27 93.7 8.4 4.9e-15 55.5 2.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK68338.1 - 4.7e-26 90.7 14.0 1.9e-14 53.5 0.7 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KIK68338.1 - 0.00013 22.2 2.3 0.16 12.3 0.2 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 KIK68338.1 - 0.018 14.9 0.2 0.018 14.9 0.2 2.5 3 1 1 4 4 4 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KIK68338.1 - 0.08 13.1 4.5 0.085 13.1 0.4 2.5 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 KIK68338.1 - 0.11 12.6 1.2 1.3 9.3 0.1 2.4 2 1 0 2 2 2 0 Rap1 Myb domain Rap1_C PF11626.8 KIK68338.1 - 0.13 12.4 1.7 1.4 9.1 1.7 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GST_N_3 PF13417.6 KIK68339.1 - 7.9e-17 61.4 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK68339.1 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK68339.1 - 1.8e-11 44.1 0.0 3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK68339.1 - 1.2e-08 35.2 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KIK68339.1 - 7.6e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 KIK68339.1 - 1.8e-05 24.8 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK68339.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DNA_circ_N PF07157.12 KIK68339.1 - 0.088 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 DNA circularisation protein N-terminus UcrQ PF02939.16 KIK68340.1 - 2.5e-26 91.4 3.5 2.7e-26 91.3 3.5 1.0 1 0 0 1 1 1 1 UcrQ family Ribonuc_2-5A PF06479.12 KIK68343.1 - 1.9e-45 154.1 1.6 4.3e-45 153.0 0.7 2.2 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KIK68343.1 - 1.2e-34 119.9 0.0 2.1e-25 89.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68343.1 - 1.2e-18 67.3 0.0 5.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 KIK68343.1 - 0.0022 17.8 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.14 KIK68343.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK68343.1 - 0.072 11.9 0.0 0.3 9.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KIK68343.1 - 0.1 12.5 0.1 1.1 9.1 0.1 2.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Caleosin PF05042.13 KIK68344.1 - 1e-15 58.1 0.2 1.7e-15 57.3 0.2 1.3 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KIK68344.1 - 0.097 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain zf-C2H2 PF00096.26 KIK68346.1 - 3.4e-12 46.1 14.4 3.2e-06 27.3 5.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK68346.1 - 1e-08 35.3 10.5 0.00056 20.5 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK68346.1 - 1e-07 32.0 13.1 2.2e-05 24.7 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KIK68346.1 - 6e-05 23.3 4.1 0.00022 21.5 1.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK68346.1 - 0.0002 21.3 1.8 0.0002 21.3 1.8 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK68346.1 - 0.0014 18.9 8.2 0.0018 18.5 1.0 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KIK68346.1 - 0.002 18.0 6.5 0.035 14.0 2.4 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 KIK68346.1 - 0.0061 16.4 8.6 0.29 11.1 1.3 2.5 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIK68346.1 - 0.013 15.8 2.2 3.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIK68346.1 - 0.04 14.2 4.2 0.074 13.4 1.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 KIK68346.1 - 0.079 13.7 1.0 5.6 7.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 KIK68346.1 - 0.16 12.1 3.1 11 6.2 1.1 2.2 1 1 2 3 3 3 0 Zinc ribbon domain CpXC PF14353.6 KIK68346.1 - 0.21 11.6 1.4 7.3 6.7 0.1 2.0 1 1 1 2 2 2 0 CpXC protein zf-BED PF02892.15 KIK68346.1 - 0.27 11.3 8.0 7.2 6.7 8.0 2.1 1 1 0 1 1 1 0 BED zinc finger IBR PF01485.21 KIK68346.1 - 0.54 10.5 6.0 2.8 8.2 0.4 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_aberr PF17017.5 KIK68347.1 - 0.00086 19.5 0.3 1.2 9.2 0.4 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KIK68347.1 - 0.0011 19.2 6.6 0.094 13.2 1.0 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type ANAPC_CDC26 PF10471.9 KIK68347.1 - 0.022 15.6 0.7 0.022 15.6 0.7 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF5302 PF17227.2 KIK68347.1 - 3 8.9 7.7 1.2 10.2 2.9 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5302) zf-C2H2_4 PF13894.6 KIK68347.1 - 6.9 7.8 14.3 4.8 8.3 0.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK68347.1 - 8.1 7.1 6.7 5.5 7.6 2.6 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Zn_clus PF00172.18 KIK68348.1 - 1.8e-05 24.7 9.5 3.1e-05 24.0 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KIK68348.1 - 0.18 11.8 0.0 0.54 10.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold TBCC PF07986.12 KIK68349.1 - 1.3e-25 89.5 0.1 2.3e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KIK68349.1 - 5.5e-10 39.7 0.2 1.1e-09 38.7 0.2 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TssO PF17561.2 KIK68350.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO Macoilin PF09726.9 KIK68351.1 - 0.0018 17.0 2.6 0.0025 16.5 2.6 1.1 1 0 0 1 1 1 1 Macoilin family Aldedh PF00171.22 KIK68352.1 - 4.2e-121 404.7 0.1 2.9e-116 388.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family OmdA PF13376.6 KIK68352.1 - 0.073 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated WD40 PF00400.32 KIK68353.1 - 2.6e-09 37.5 9.3 0.02 15.7 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat SGL PF08450.12 KIK68353.1 - 6.1e-05 22.7 0.1 0.013 15.1 0.0 3.0 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KIK68353.1 - 0.0058 16.9 0.1 2.6 8.4 0.0 3.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KIK68353.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40_like PF17005.5 KIK68353.1 - 0.13 11.6 0.0 0.42 9.9 0.0 1.7 1 1 1 2 2 2 0 WD40-like domain Utp8 PF10395.9 KIK68353.1 - 0.23 9.9 0.1 0.51 8.8 0.0 1.6 1 1 1 2 2 2 0 Utp8 family Aldo_ket_red PF00248.21 KIK68354.1 - 6.4e-65 219.2 0.0 7.3e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KIK68355.1 - 2.3e-30 105.5 0.0 3.5e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK68355.1 - 2.4e-22 79.6 0.0 8.8e-22 77.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK68355.1 - 0.00025 21.0 0.0 0.0006 19.8 0.0 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK68355.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SET PF00856.28 KIK68357.1 - 1.7e-19 70.8 0.1 1.7e-19 70.8 0.1 3.2 2 2 0 2 2 2 1 SET domain N-SET PF11764.8 KIK68357.1 - 2.2e-10 40.9 7.8 2.2e-10 40.9 7.8 3.3 2 2 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KIK68357.1 - 0.00015 21.4 0.0 0.00058 19.4 0.0 2.0 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Ca_hom_mod PF14798.6 KIK68358.1 - 0.16 11.0 0.1 0.24 10.5 0.1 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator HAD_2 PF13419.6 KIK68359.1 - 6e-07 29.7 0.0 1e-06 29.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK68359.1 - 0.00026 21.0 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIK68359.1 - 0.0012 19.2 0.0 0.014 15.7 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KIK68359.1 - 0.047 13.2 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) PRA1 PF03208.19 KIK68361.1 - 8.2 6.1 9.6 1.1 8.9 1.7 2.6 1 1 2 3 3 3 0 PRA1 family protein HeLo PF14479.6 KIK68363.1 - 2e-26 93.1 0.0 3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 KIK68363.1 - 2.1e-05 24.1 0.0 0.0035 16.7 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68363.1 - 0.0048 16.2 0.0 0.027 13.8 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Hydrolase_4 PF12146.8 KIK68364.1 - 1.9e-20 73.2 0.5 3.1e-17 62.6 0.2 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK68364.1 - 1.5e-11 44.5 0.6 3.1e-09 36.9 0.4 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68364.1 - 3.9e-11 44.0 0.9 1.2e-10 42.3 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KIK68364.1 - 3.1e-07 30.4 0.1 0.04 13.7 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KIK68364.1 - 4.7e-05 23.0 0.0 0.00069 19.1 0.0 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KIK68364.1 - 8.1e-05 22.6 0.1 0.0088 16.0 0.0 2.9 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KIK68364.1 - 0.00032 20.5 0.1 0.00069 19.4 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KIK68364.1 - 0.0035 17.0 0.0 0.0066 16.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 KIK68364.1 - 0.0035 16.9 0.0 0.02 14.5 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KIK68364.1 - 0.013 15.3 0.0 0.054 13.3 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KIK68364.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 KIK68364.1 - 0.017 14.1 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 KIK68364.1 - 0.019 14.7 0.0 0.046 13.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.16 KIK68364.1 - 0.069 12.7 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region LIDHydrolase PF10230.9 KIK68364.1 - 0.081 12.5 0.0 0.26 10.8 0.0 1.8 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Fungal_trans PF04082.18 KIK68365.1 - 1e-25 90.3 0.0 3.2e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_5_C PF18564.1 KIK68366.1 - 7.7e-23 80.8 0.0 1.6e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KIK68366.1 - 2.4e-12 46.9 0.0 2e-07 30.8 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) zf-Paramyx-P PF13008.7 KIK68366.1 - 0.027 13.9 0.5 0.058 12.9 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein F-box-like PF12937.7 KIK68367.1 - 0.042 13.7 0.3 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 F-box-like Cytochrom_B561 PF03188.16 KIK68369.1 - 0.0014 18.8 9.0 0.004 17.3 9.0 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KIK68369.1 - 0.011 15.9 9.9 1.5 9.0 3.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF2628 PF10947.8 KIK68369.1 - 0.018 15.4 9.4 0.49 10.8 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF998 PF06197.13 KIK68369.1 - 2.6 7.6 18.5 0.36 10.4 11.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) zf-CCCH_4 PF18044.1 KIK68370.1 - 1.9e-08 33.9 7.7 4.7e-05 23.1 0.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KIK68370.1 - 3.5e-06 27.7 4.9 0.021 15.5 0.3 2.7 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KIK68370.1 - 8.3e-06 25.7 10.7 3.2e-05 23.8 1.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KIK68370.1 - 4.3e-05 23.3 6.4 0.00046 20.0 1.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KIK68370.1 - 0.0018 18.5 0.9 0.0035 17.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KIK68370.1 - 2.8 8.5 12.1 0.26 11.8 2.3 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ArsB PF02040.15 KIK68372.1 - 1e-11 44.8 21.1 6.2e-08 32.4 11.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein SR-25 PF10500.9 KIK68373.1 - 0.0015 18.2 2.0 0.002 17.8 2.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4726 PF15855.5 KIK68373.1 - 0.022 15.0 0.4 0.046 13.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) DUF3138 PF11336.8 KIK68373.1 - 0.038 12.6 0.2 0.038 12.6 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF3327 PF11806.8 KIK68373.1 - 0.53 11.0 2.5 1.1 10.0 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3327) Tetraspanin PF00335.20 KIK68375.1 - 0.0052 16.5 5.7 0.0052 16.5 5.7 1.9 1 1 0 2 2 2 1 Tetraspanin family Peptidase_S10 PF00450.22 KIK68376.1 - 8.7e-94 315.3 3.0 1e-93 315.0 3.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-RING_UBOX PF13445.6 KIK68377.1 - 4.6e-07 29.7 4.4 4.6e-07 29.7 4.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK68377.1 - 1.1e-06 28.4 7.4 1.2e-06 28.3 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK68377.1 - 1.4e-06 28.3 5.9 5.4e-06 26.5 2.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KIK68377.1 - 4.7e-06 26.4 9.7 0.0003 20.6 5.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK68377.1 - 9.1e-06 25.4 7.0 0.00091 19.0 3.5 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK68377.1 - 6e-05 22.9 9.9 0.0006 19.7 9.9 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK68377.1 - 0.00088 19.6 12.6 0.0097 16.2 8.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK68377.1 - 0.0017 18.2 7.2 0.0017 18.2 7.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FlxA PF14282.6 KIK68377.1 - 0.011 15.8 0.7 0.02 14.9 0.7 1.5 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.8 KIK68377.1 - 0.017 15.1 2.4 0.036 14.1 2.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lipoprotein_20 PF13942.6 KIK68377.1 - 0.018 15.0 0.7 0.026 14.5 0.7 1.2 1 0 0 1 1 1 0 YfhG lipoprotein DUF4164 PF13747.6 KIK68377.1 - 0.02 15.2 1.8 0.032 14.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Tropomyosin_1 PF12718.7 KIK68377.1 - 0.033 14.4 3.8 0.053 13.7 3.8 1.3 1 0 0 1 1 1 0 Tropomyosin like AAA_32 PF13654.6 KIK68377.1 - 0.041 12.7 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.11 KIK68377.1 - 0.045 14.3 1.6 0.093 13.3 1.6 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 KIK68377.1 - 0.051 14.0 0.2 0.086 13.3 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 KIK68377.1 - 0.12 11.3 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rx_N PF18052.1 KIK68377.1 - 0.17 12.2 0.8 2.1 8.7 0.8 2.2 2 0 0 2 2 2 0 Rx N-terminal domain APG6_N PF17675.1 KIK68377.1 - 0.27 11.7 8.2 0.35 11.4 3.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIK68377.1 - 0.66 9.8 4.0 1.3 8.8 4.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Zn_ribbon_17 PF17120.5 KIK68377.1 - 2.5 7.8 10.3 2.7 7.7 7.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Glyco_hydro_127 PF07944.12 KIK68378.1 - 5.1e-22 78.1 0.0 4.3e-21 75.0 0.0 1.9 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Questin_oxidase PF14027.6 KIK68379.1 - 2.6e-100 336.3 0.0 3.2e-100 336.0 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Gly_transf_sug PF04488.15 KIK68380.1 - 6.2e-06 26.8 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK68380.1 - 0.052 12.9 0.2 0.083 12.3 0.2 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF5036 PF16439.5 KIK68382.1 - 0.051 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5036) DUF262 PF03235.14 KIK68384.1 - 6e-18 65.8 0.1 1.7e-17 64.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF3106 PF11304.8 KIK68384.1 - 0.22 12.0 10.6 0.58 10.7 8.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Ric8 PF10165.9 KIK68387.1 - 4.5e-117 391.9 0.0 5.5e-117 391.6 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Pkinase PF00069.25 KIK68389.1 - 6e-63 212.7 0.0 1.7e-62 211.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68389.1 - 3.2e-44 151.2 0.0 1.1e-43 149.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 KIK68389.1 - 1.2e-35 123.1 0.2 2.8e-35 121.9 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 KIK68389.1 - 0.0019 18.1 3.7 0.022 14.7 0.1 3.2 2 2 2 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK68389.1 - 0.075 11.8 0.0 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase RNA_Me_trans PF04252.13 KIK68390.1 - 5.2e-75 251.4 0.0 5.8e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Herpes_LAMP2 PF06126.11 KIK68391.1 - 0.051 12.2 0.5 0.075 11.7 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 EMP70 PF02990.16 KIK68391.1 - 0.2 10.3 3.3 0.34 9.5 3.3 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 DUF1129 PF06570.11 KIK68391.1 - 1 8.8 4.3 0.53 9.7 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Srg PF02118.21 KIK68391.1 - 3.4 7.3 9.4 0.3 10.7 5.0 1.4 2 0 0 2 2 2 0 Srg family chemoreceptor Tetraspanin PF00335.20 KIK68391.1 - 6.1 6.5 7.8 2.6 7.7 5.6 1.5 1 1 0 1 1 1 0 Tetraspanin family 7tm_2 PF00002.24 KIK68392.1 - 0.012 14.9 2.6 0.022 14.0 2.5 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) F-box-like PF12937.7 KIK68394.1 - 1.8e-07 31.0 0.3 8.3e-07 28.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK68394.1 - 0.44 10.5 2.0 1.6 8.7 0.2 2.9 4 0 0 4 4 4 0 F-box domain Myb_DNA-binding PF00249.31 KIK68395.1 - 1.6e-08 34.6 1.4 2.4e-08 34.0 0.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK68395.1 - 0.00067 19.9 0.3 0.0017 18.6 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain KorB PF08535.10 KIK68395.1 - 0.026 14.5 0.1 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 KorB domain DUF2664 PF10867.8 KIK68395.1 - 0.6 10.6 0.1 0.6 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Polysacc_synt_4 PF04669.13 KIK68396.1 - 4.2e-17 62.3 0.8 1.8e-15 57.0 0.5 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.9 KIK68396.1 - 0.0092 15.2 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) bZIP_1 PF00170.21 KIK68398.1 - 9.6e-06 25.6 8.2 0.00012 22.1 1.6 2.6 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 KIK68398.1 - 0.00078 19.5 13.4 0.0067 16.5 4.7 2.3 2 0 0 2 2 2 2 Basic region leucine zipper YabA PF06156.13 KIK68398.1 - 0.027 15.1 0.0 0.068 13.8 0.0 1.5 1 1 0 1 1 1 0 Initiation control protein YabA Shugoshin_N PF07558.11 KIK68398.1 - 0.03 14.2 2.0 0.11 12.4 0.6 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 KIK68398.1 - 0.066 13.3 2.6 0.27 11.3 0.4 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain TSC22 PF01166.18 KIK68398.1 - 0.25 11.7 2.0 0.71 10.2 0.5 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 KIK68398.1 - 0.3 11.2 4.3 0.23 11.6 1.4 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 KIK68398.1 - 3.3 7.5 6.4 7.5 6.4 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator TAL_FSA PF00923.19 KIK68400.1 - 1.1e-18 67.6 0.0 2.6e-18 66.4 0.0 1.4 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PIG-F PF06699.11 KIK68401.1 - 1.4e-33 116.6 7.9 2e-33 116.1 7.9 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F FA_desaturase PF00487.24 KIK68401.1 - 1.4 8.7 9.5 0.14 12.0 4.7 1.8 1 1 1 2 2 2 0 Fatty acid desaturase Hydrolase_6 PF13344.6 KIK68402.1 - 6.3e-31 106.5 0.0 1.2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK68402.1 - 1.8e-18 66.4 0.0 4.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIK68402.1 - 2e-12 47.9 0.1 3.9e-12 46.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK68402.1 - 1.1e-09 38.6 0.0 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KIK68402.1 - 0.0046 16.6 0.0 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase ERG2_Sigma1R PF04622.12 KIK68403.1 - 1.5e-93 312.0 0.0 1.6e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein CAP59_mtransfer PF11735.8 KIK68404.1 - 8.2e-69 231.9 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Amidohydro_1 PF01979.20 KIK68405.1 - 8.6e-37 127.2 0.3 1e-36 126.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK68405.1 - 4.5e-14 52.8 0.5 6.4e-10 39.1 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family DeoC PF01791.9 KIK68405.1 - 0.07 12.7 0.2 3.6 7.1 0.1 2.2 2 0 0 2 2 2 0 DeoC/LacD family aldolase Orthopox_C10L PF07020.11 KIK68405.1 - 0.075 13.8 1.8 0.16 12.7 1.8 1.6 1 0 0 1 1 1 0 Orthopoxvirus C10L protein Molybdopterin_N PF18364.1 KIK68405.1 - 0.32 11.1 1.6 3.3 7.8 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain adh_short PF00106.25 KIK68406.1 - 5.6e-21 74.9 0.0 7.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK68406.1 - 8.9e-10 38.5 0.0 1.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK68406.1 - 1.5e-05 25.0 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK68406.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exog_C PF18026.1 KIK68406.1 - 0.00057 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain THF_DHG_CYH_C PF02882.19 KIK68406.1 - 0.0022 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SARAF PF06682.12 KIK68406.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis NAD_binding_7 PF13241.6 KIK68406.1 - 0.026 15.0 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 KIK68406.1 - 0.043 13.8 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DFP PF04127.15 KIK68406.1 - 0.094 12.5 0.2 0.24 11.2 0.2 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 KIK68406.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pox_A28 PF04584.14 KIK68407.1 - 0.043 14.0 0.9 0.79 9.9 0.3 2.5 2 0 0 2 2 2 0 Poxvirus A28 family RPN7 PF10602.9 KIK68408.1 - 2.6e-33 115.2 0.0 4.3e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIK68408.1 - 1.3e-15 57.8 0.0 2.9e-14 53.5 0.0 2.6 2 1 0 2 2 2 1 PCI domain CFEM PF05730.11 KIK68409.1 - 6.3e-11 42.2 13.1 1.1e-10 41.4 13.1 1.3 1 0 0 1 1 1 1 CFEM domain peroxidase PF00141.23 KIK68410.1 - 1.1e-19 71.1 0.0 1.5e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase ADH_N PF08240.12 KIK68412.1 - 6.6e-31 106.4 2.9 2.5e-30 104.6 3.5 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK68412.1 - 2.5e-16 59.8 0.0 4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK68412.1 - 9.9e-06 25.0 0.1 1.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KIK68412.1 - 4.8e-05 24.4 0.0 7.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIK68412.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KIK68412.1 - 0.0018 18.6 0.0 0.0084 16.4 0.0 2.0 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KIK68412.1 - 0.0067 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF5612 PF18462.1 KIK68412.1 - 0.042 13.6 0.1 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) DUF1115 PF06544.12 KIK68413.1 - 5.7e-08 33.0 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) WW PF00397.26 KIK68415.1 - 3.6e-09 36.6 8.0 7.5e-09 35.5 5.3 2.5 2 0 0 2 2 2 1 WW domain Adeno_E3_CR2 PF02439.15 KIK68416.1 - 0.66 9.8 1.7 2.1 8.1 1.7 1.9 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 OppC_N PF12911.7 KIK68416.1 - 0.91 9.5 2.8 0.59 10.2 0.4 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MmgE_PrpD PF03972.14 KIK68417.1 - 8e-113 377.3 4.1 9.5e-113 377.0 4.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Abhydrolase_4 PF08386.10 KIK68417.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein PTPA PF03095.15 KIK68418.1 - 4.7e-126 420.3 0.1 5.4e-126 420.1 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SURF6 PF04935.12 KIK68419.1 - 2.7e-43 148.1 64.8 3.1e-43 147.9 47.7 2.2 2 0 0 2 2 2 2 Surfeit locus protein 6 RRP14 PF15459.6 KIK68419.1 - 2.4e-20 72.9 9.7 2.4e-20 72.9 9.7 5.3 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Cation_efflux PF01545.21 KIK68420.1 - 0.0001 22.1 0.4 0.00028 20.7 0.4 1.7 1 1 0 1 1 1 1 Cation efflux family Glyco_hydro_18 PF00704.28 KIK68421.1 - 8.8e-20 71.6 1.4 1.2e-19 71.2 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 N2227 PF07942.12 KIK68422.1 - 3.2e-91 305.3 0.0 4.1e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KIK68422.1 - 0.016 15.9 0.0 0.077 13.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF2052 PF09747.9 KIK68422.1 - 0.063 13.4 0.5 0.095 12.8 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Methyltransf_11 PF08241.12 KIK68422.1 - 0.11 13.2 0.0 3.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MMR_HSR1 PF01926.23 KIK68423.1 - 8.3e-09 35.5 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK68423.1 - 8.8e-08 31.7 0.0 1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIK68423.1 - 0.00052 20.5 0.1 0.0014 19.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KIK68423.1 - 0.00056 19.8 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK68423.1 - 0.00076 19.9 0.0 0.0013 19.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK68423.1 - 0.0018 18.6 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Dynamin_N PF00350.23 KIK68423.1 - 0.0044 17.1 0.2 0.028 14.5 0.2 2.2 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 KIK68423.1 - 0.01 16.1 0.9 0.052 13.8 0.1 2.2 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KIK68423.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIK68423.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KIK68423.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KIK68423.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KIK68423.1 - 0.097 12.3 0.3 0.22 11.1 0.1 1.6 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 KIK68424.1 - 0.019 14.1 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 KIK68424.1 - 0.035 14.4 0.3 0.11 12.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain DUF3158 PF11358.8 KIK68424.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) CPT PF07931.12 KIK68424.1 - 0.11 12.3 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Roc PF08477.13 KIK68424.1 - 0.15 12.3 0.1 0.94 9.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIK68425.1 - 2.5e-08 34.0 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK68425.1 - 3.3e-07 29.8 0.0 4.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK68425.1 - 0.0035 17.4 0.2 0.011 15.8 0.1 1.8 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK68425.1 - 0.0037 17.2 0.1 0.0084 16.0 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIK68425.1 - 0.0051 17.2 0.1 0.023 15.1 0.0 2.1 3 1 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 KIK68425.1 - 0.023 14.9 0.3 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KIK68425.1 - 0.039 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KIK68425.1 - 0.039 14.5 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KIK68425.1 - 0.089 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KIK68425.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Zeta_toxin PF06414.12 KIK68425.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KIK68425.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIK68425.1 - 0.14 12.4 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK68426.1 - 1.7e-07 31.3 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK68426.1 - 7.1e-05 22.2 0.0 0.00015 21.1 0.0 1.6 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KIK68426.1 - 0.00072 19.7 0.1 0.0022 18.1 0.1 1.8 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK68426.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase zf-MYND PF01753.18 KIK68426.1 - 0.0022 18.0 1.1 0.0064 16.5 1.1 1.8 1 0 0 1 1 1 1 MYND finger ABC_tran PF00005.27 KIK68426.1 - 0.0029 18.1 0.1 0.0089 16.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KIK68426.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KIK68426.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KIK68426.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KIK68426.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KIK68426.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK68426.1 - 0.15 11.8 0.3 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain TMEM154 PF15102.6 KIK68428.1 - 0.0022 17.9 0.8 0.0046 16.9 0.1 1.8 2 0 0 2 2 2 1 TMEM154 protein family BatD PF13584.6 KIK68428.1 - 0.014 14.2 0.5 0.03 13.2 0.0 1.6 2 0 0 2 2 2 0 Oxygen tolerance Orf78 PF06024.12 KIK68428.1 - 0.017 15.4 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) RIFIN PF02009.16 KIK68428.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Rifin Herpes_gE PF02480.16 KIK68428.1 - 0.027 13.2 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CCDC154 PF15450.6 KIK68428.1 - 0.056 12.0 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Rax2 PF12768.7 KIK68428.1 - 0.065 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 KIK68428.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF5534 PF17686.1 KIK68428.1 - 0.17 12.1 0.9 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5534) BatA PF07584.11 KIK68428.1 - 0.26 11.7 1.2 5.6 7.4 0.2 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PGF-CTERM PF18204.1 KIK68428.1 - 0.48 10.5 2.9 0.86 9.7 2.9 1.3 1 0 0 1 1 1 0 PGF-CTERM motif Med3 PF11593.8 KIK68428.1 - 1.8 7.7 7.5 0.043 13.0 1.1 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal F-box-like PF12937.7 KIK68429.1 - 0.03 14.2 0.7 0.03 14.2 0.7 2.4 3 0 0 3 3 3 0 F-box-like Molybdopterin PF00384.22 KIK68431.1 - 1.2e-67 228.8 0.0 1.3e-66 225.3 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KIK68431.1 - 7.6e-20 70.8 0.3 1.7e-19 69.6 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KIK68431.1 - 2.5e-17 62.1 0.2 2.5e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KIK68431.1 - 1.1e-14 54.8 0.0 2.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KIK68431.1 - 1.6e-08 34.3 0.6 1.6e-08 34.3 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KIK68431.1 - 0.054 13.2 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KIK68431.1 - 0.1 12.5 1.1 4.8 7.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Glyco_transf_90 PF05686.12 KIK68432.1 - 1.1e-07 31.1 0.0 2.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 90 Chitin_synth_2 PF03142.15 KIK68433.1 - 4.9e-236 784.4 1.2 6.8e-236 784.0 1.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIK68433.1 - 2.8e-141 472.0 0.0 1e-140 470.1 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KIK68433.1 - 3.4e-16 58.9 0.0 1.4e-15 56.9 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KIK68433.1 - 4.1e-09 36.7 3.6 4.1e-09 36.7 3.6 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KIK68433.1 - 7.8e-08 32.4 0.1 9e-06 25.8 0.0 3.2 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KIK68433.1 - 1e-07 32.1 0.0 5.4e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK68433.1 - 0.012 15.5 0.0 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Baculo_LEF5 PF04838.12 KIK68433.1 - 0.15 12.1 0.0 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 Ras PF00071.22 KIK68436.1 - 1.9e-54 183.6 0.0 2.2e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK68436.1 - 9e-22 77.5 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK68436.1 - 1.3e-06 28.0 0.0 2e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK68436.1 - 0.0031 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK68436.1 - 0.22 10.8 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region F-box-like PF12937.7 KIK68437.1 - 0.00083 19.2 2.6 0.0024 17.7 2.6 1.9 1 0 0 1 1 1 1 F-box-like 4HBT PF03061.22 KIK68439.1 - 5.2e-10 39.6 0.1 9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KIK68439.1 - 1.9e-05 25.1 0.0 3e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily DnaJ PF00226.31 KIK68440.1 - 2.6e-15 56.3 2.4 1.8e-14 53.6 2.4 2.4 1 1 0 1 1 1 1 DnaJ domain C2-set PF05790.15 KIK68440.1 - 0.59 10.4 0.0 0.59 10.4 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin C2-set domain Borrelia_P83 PF05262.11 KIK68440.1 - 2.7 6.4 30.6 0.078 11.5 21.8 2.2 2 1 0 2 2 2 0 Borrelia P83/100 protein Pkinase PF00069.25 KIK68441.1 - 3.6e-66 223.2 0.0 4.2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68441.1 - 9.6e-30 103.7 0.0 1e-28 100.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KIK68441.1 - 0.00068 19.0 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK68441.1 - 0.00069 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK68441.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK68441.1 - 0.055 13.4 0.4 0.12 12.3 0.3 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK68441.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIK68441.1 - 0.22 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EthD PF07110.11 KIK68442.1 - 0.03 15.5 0.1 1.9 9.7 0.0 2.4 2 0 0 2 2 2 0 EthD domain Pinin_SDK_memA PF04696.13 KIK68444.1 - 7.6e-09 35.7 15.2 7.6e-09 35.7 15.2 3.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region Vfa1 PF08432.10 KIK68444.1 - 9.1 6.6 15.8 3 8.2 5.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Peptidase_C13 PF01650.18 KIK68445.1 - 1.1e-43 149.6 0.5 1.4e-43 149.3 0.5 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KIK68445.1 - 0.17 12.2 0.1 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 Mid domain of argonaute UPF0261 PF06792.11 KIK68446.1 - 1.4e-150 501.8 0.0 1.5e-150 501.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Cnn_1N PF07989.11 KIK68447.1 - 0.00071 19.7 6.5 0.0085 16.2 0.2 2.9 1 1 0 2 2 2 1 Centrosomin N-terminal motif 1 CENP-H PF05837.12 KIK68447.1 - 0.0046 17.3 12.7 0.16 12.4 4.2 2.5 1 1 1 2 2 2 2 Centromere protein H (CENP-H) Filament PF00038.21 KIK68447.1 - 0.022 14.3 10.9 0.072 12.7 10.6 1.9 1 1 0 1 1 1 0 Intermediate filament protein Exonuc_VII_S PF02609.16 KIK68447.1 - 0.027 14.5 1.1 0.16 12.1 0.4 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit bZIP_1 PF00170.21 KIK68447.1 - 0.039 14.1 7.5 0.25 11.5 0.6 3.4 3 1 0 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.19 KIK68447.1 - 0.094 10.6 2.1 0.097 10.6 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ThrE PF06738.12 KIK68447.1 - 0.15 11.4 0.4 0.63 9.4 0.6 1.8 1 1 1 2 2 2 0 Putative threonine/serine exporter TMPIT PF07851.13 KIK68447.1 - 0.17 11.1 3.0 0.23 10.7 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein GIT_CC PF16559.5 KIK68447.1 - 0.2 11.6 8.7 0.15 11.9 1.2 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CASP_C PF08172.12 KIK68447.1 - 0.34 10.2 7.3 1.1 8.6 0.9 2.5 1 1 0 2 2 2 0 CASP C terminal YycI PF09648.10 KIK68447.1 - 0.62 9.6 7.5 1 8.9 7.5 1.5 1 1 0 1 1 1 0 YycH protein SecD-TM1 PF13721.6 KIK68447.1 - 0.97 9.9 5.0 2.7 8.5 4.4 2.0 1 1 1 2 2 2 0 SecD export protein N-terminal TM region ZapB PF06005.12 KIK68447.1 - 2.6 8.6 14.6 8.4 6.9 6.0 3.0 1 1 1 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 KIK68447.1 - 3 8.3 7.8 6.4 7.3 1.0 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KIK68447.1 - 3.8 7.4 13.1 0.51 10.1 1.7 3.3 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.6 KIK68447.1 - 4 6.7 17.2 0.73 9.1 12.6 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 KIK68447.1 - 5 7.5 13.5 0.83 10.0 2.9 3.6 3 1 1 4 4 4 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KIK68447.1 - 9.6 6.3 17.8 8.2 6.5 7.2 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.32 KIK68449.1 - 4.8e-53 175.9 20.1 4.4e-08 33.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68449.1 - 2.2e-19 69.5 0.3 5.7e-05 23.3 0.0 6.1 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KIK68449.1 - 4.6e-15 55.7 0.3 7.6e-15 55.0 0.3 1.3 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KIK68449.1 - 4.1e-09 36.2 0.0 0.027 13.8 0.0 4.7 5 1 1 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 KIK68449.1 - 8.9e-08 31.5 1.1 0.92 8.4 0.0 5.4 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK68449.1 - 0.0016 18.4 0.0 0.71 9.7 0.0 3.4 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK68449.1 - 0.0025 16.4 1.3 0.071 11.6 0.1 3.1 2 1 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK68449.1 - 0.0027 17.6 0.0 49 4.0 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK68449.1 - 0.0033 16.8 0.5 12 5.1 0.0 3.5 2 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK68449.1 - 0.0084 14.8 0.1 0.16 10.6 0.0 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 CEP63 PF17045.5 KIK68449.1 - 0.12 12.2 1.2 0.17 11.8 0.4 1.6 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa VID27 PF08553.10 KIK68449.1 - 0.15 11.1 0.0 8.3 5.4 0.0 2.8 2 1 0 3 3 3 0 VID27 C-terminal WD40-like domain ImmE5 PF11480.8 KIK68449.1 - 0.18 12.3 0.1 0.57 10.7 0.1 1.8 1 0 0 1 1 1 0 Colicin-E5 Imm protein Cellulase PF00150.18 KIK68450.1 - 8.9e-30 104.1 3.0 1.3e-29 103.6 3.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK68450.1 - 2.4e-12 46.6 5.4 2.4e-12 46.6 5.4 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KIK68450.1 - 4.3e-05 22.8 0.0 0.001 18.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KIK68450.1 - 0.005 16.2 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase MFMR PF07777.11 KIK68450.1 - 0.29 11.6 3.0 1.9 9.0 0.0 3.5 3 1 0 3 3 3 0 G-box binding protein MFMR UPF0240 PF06784.11 KIK68451.1 - 5.1 7.1 11.9 0.25 11.4 1.6 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0240) DSPc PF00782.20 KIK68452.1 - 1.1e-28 99.7 0.0 3.2e-28 98.2 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK68452.1 - 0.00018 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cellulase PF00150.18 KIK68453.1 - 9.2e-26 90.9 2.8 1.4e-25 90.3 2.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIK68453.1 - 5.3e-12 45.5 2.3 5.3e-12 45.5 2.3 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KIK68453.1 - 7.4e-05 22.0 0.0 0.00019 20.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KIK68453.1 - 0.0015 18.2 0.4 0.002 17.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KIK68453.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase RNA_pol_L_2 PF13656.6 KIK68455.1 - 3.4e-30 103.6 0.0 4.4e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIK68455.1 - 2.3e-07 30.1 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Filament PF00038.21 KIK68457.1 - 0.26 10.8 52.7 0.047 13.3 3.0 3.8 1 1 2 3 3 3 0 Intermediate filament protein AT_hook PF02178.19 KIK68457.1 - 0.38 10.8 9.2 0.14 12.2 6.0 2.1 2 0 0 2 2 2 0 AT hook motif MPS2 PF17060.5 KIK68457.1 - 1.1 8.5 20.8 0.03 13.6 12.0 2.2 1 1 0 2 2 2 0 Monopolar spindle protein 2 Mcp5_PH PF12814.7 KIK68458.1 - 5.4e-45 152.4 0.1 9.7e-45 151.6 0.1 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KIK68458.1 - 7.5e-06 26.4 0.0 1.9e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Fez1 PF06818.15 KIK68458.1 - 0.01 16.3 16.3 0.01 16.3 16.3 3.4 3 0 0 3 3 3 1 Fez1 Mce4_CUP1 PF11887.8 KIK68458.1 - 0.087 12.3 6.2 0.18 11.2 6.2 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Prominin PF05478.11 KIK68458.1 - 0.13 10.2 10.6 0.29 9.1 10.6 1.5 1 0 0 1 1 1 0 Prominin Cbl_N PF02262.16 KIK68458.1 - 1.9 8.5 4.0 2.7 8.0 2.1 2.1 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF5340 PF17275.2 KIK68458.1 - 2.9 8.1 7.3 0.42 10.8 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5340) DUF667 PF05018.13 KIK68459.1 - 2.2e-23 82.9 0.0 9.4e-13 48.3 0.0 3.6 3 1 0 3 3 3 3 Protein of unknown function (DUF667) Rad60-SLD PF11976.8 KIK68460.1 - 6.2e-23 80.4 0.1 7.7e-23 80.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIK68460.1 - 3.4e-12 45.9 0.0 4.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Dermcidin PF15291.6 KIK68461.1 - 0.014 15.9 0.5 0.68 10.5 0.0 3.4 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide Nsp1_C PF05064.13 KIK68462.1 - 0.014 15.2 0.1 0.03 14.1 0.0 1.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region P4Ha_N PF08336.11 KIK68462.1 - 0.077 13.0 0.1 0.094 12.7 0.1 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PDEase_I PF00233.19 KIK68464.1 - 3.3e-52 177.6 0.0 8.7e-52 176.2 0.0 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Sec23_trunk PF04811.15 KIK68465.1 - 2.7e-49 168.0 0.0 4e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIK68465.1 - 5.3e-23 80.8 0.7 9.5e-23 80.0 0.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KIK68465.1 - 3.2e-15 55.9 4.4 6.6e-15 54.9 4.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KIK68465.1 - 1.9e-14 54.2 0.0 4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KIK68465.1 - 1.3e-05 25.0 0.0 3.1e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Gelsolin repeat Glyco_hydro_47 PF01532.20 KIK68466.1 - 2.2e-120 402.6 0.2 2.6e-120 402.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 tRNA-synt_His PF13393.6 KIK68467.1 - 1.2e-37 129.9 0.0 6.4e-34 117.6 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KIK68467.1 - 5.1e-09 36.2 0.2 1e-08 35.2 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain SGL PF08450.12 KIK68469.1 - 1.8e-09 37.5 0.0 8.8e-07 28.7 0.1 2.4 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KIK68469.1 - 0.0045 16.3 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ PF01011.21 KIK68469.1 - 0.015 15.2 0.9 0.082 12.9 0.3 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Arylesterase PF01731.20 KIK68469.1 - 0.038 14.2 0.1 12 6.1 0.0 3.7 3 1 0 3 3 3 0 Arylesterase VID27 PF08553.10 KIK68469.1 - 0.083 11.9 0.7 2.8 6.9 0.2 2.6 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain Baculo_VP91_N PF08475.10 KIK68471.1 - 0.074 12.7 0.7 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Sugarporin_N PF11471.8 KIK68471.1 - 0.11 12.4 0.8 0.21 11.5 0.8 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Exonuc_VII_L PF02601.15 KIK68471.1 - 0.49 9.9 3.1 4.3 6.8 0.0 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit LVIVD PF08309.11 KIK68473.1 - 1.4e-08 33.9 3.5 0.27 10.6 0.0 4.6 4 0 0 4 4 4 4 LVIVD repeat Glyco_transf_20 PF00982.21 KIK68474.1 - 3.9e-130 434.7 0.0 5.8e-129 430.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIK68474.1 - 2.2e-15 56.4 0.0 4.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase zf-dskA_traR PF01258.17 KIK68475.1 - 0.1 12.6 0.6 0.92 9.5 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger F-box-like PF12937.7 KIK68475.1 - 0.12 12.3 0.2 0.33 10.9 0.2 1.8 1 0 0 1 1 1 0 F-box-like Sec20 PF03908.13 KIK68476.1 - 1.1e-15 57.3 0.6 1.1e-15 57.3 0.6 2.3 3 0 0 3 3 3 1 Sec20 DUF5344 PF17279.2 KIK68476.1 - 0.027 15.0 0.5 0.027 15.0 0.5 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5344) Apq12 PF12716.7 KIK68476.1 - 0.097 12.6 4.1 0.22 11.5 4.1 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF4355 PF14265.6 KIK68476.1 - 2.2 8.5 10.3 4.9 7.4 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) KxDL PF10241.9 KIK68476.1 - 3.4 8.0 9.4 14 6.1 0.8 3.5 2 2 1 3 3 3 0 Uncharacterized conserved protein CorA PF01544.18 KIK68476.1 - 4.1 6.6 7.5 8.7 5.6 7.5 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Uso1_p115_C PF04871.13 KIK68476.1 - 6.4 7.2 12.6 33 4.9 12.0 2.4 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region N1221 PF07923.13 KIK68477.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 N1221-like protein DUF983 PF06170.12 KIK68477.1 - 0.62 10.5 6.2 0.32 11.4 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF983) Cytochrom_B561 PF03188.16 KIK68478.1 - 0.032 14.4 1.7 0.062 13.4 0.9 1.9 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 XPG_N PF00752.17 KIK68479.1 - 7.6e-23 80.9 0.0 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIK68479.1 - 2.9e-22 78.8 0.0 6.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KIK68479.1 - 1.9e-07 30.8 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KIK68479.1 - 5.4e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 KIK68479.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68479.1 - 0.0068 16.4 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK68479.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH_5 PF14520.6 KIK68479.1 - 0.019 15.6 0.0 0.06 14.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain TPR_11 PF13414.6 KIK68479.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 TPR repeat zf-C2H2 PF00096.26 KIK68480.1 - 2.8e-10 40.1 9.8 2.5e-05 24.5 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK68480.1 - 3.2e-07 30.6 6.9 0.00046 20.8 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIK68480.1 - 0.0016 18.8 4.8 0.0028 18.0 0.3 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK68480.1 - 0.014 15.4 0.3 0.014 15.4 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK68480.1 - 0.037 14.5 13.1 0.24 11.9 1.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK68480.1 - 0.049 13.9 1.1 0.15 12.4 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KIK68480.1 - 0.36 10.9 4.3 0.81 9.8 0.5 2.3 2 0 0 2 2 2 0 BED zinc finger 5-FTHF_cyc-lig PF01812.20 KIK68481.1 - 8.3e-41 139.9 0.0 1.1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Abhydrolase_1 PF00561.20 KIK68482.1 - 2.1e-16 60.4 0.0 3.2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68482.1 - 2.8e-14 54.2 0.4 3.7e-14 53.9 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK68482.1 - 2.9e-11 43.1 0.0 2.4e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIK68482.1 - 0.0002 21.2 0.0 0.3 10.8 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KIK68482.1 - 0.00099 18.8 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KIK68482.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAA_hydro_N_2 PF18288.1 KIK68482.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Ndr PF03096.14 KIK68482.1 - 0.19 10.4 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Rad51 PF08423.11 KIK68483.1 - 0.0001 21.6 0.0 0.00085 18.7 0.0 2.0 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KIK68483.1 - 0.00045 19.8 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KIK68483.1 - 0.028 13.8 0.0 0.072 12.4 0.0 1.6 2 0 0 2 2 2 0 KaiC RNA12 PF10443.9 KIK68483.1 - 0.076 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_22 PF13401.6 KIK68483.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2264 PF10022.9 KIK68484.1 - 1.3e-130 435.6 0.2 1.6e-130 435.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) RNB PF00773.19 KIK68485.1 - 2.4e-50 171.7 0.2 1.5e-47 162.6 0.1 2.3 2 0 0 2 2 2 2 RNB domain OB_Dis3 PF17849.1 KIK68485.1 - 6.3e-11 42.2 0.0 1.8e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 KIK68485.1 - 3.5e-09 36.5 0.5 1e-08 35.0 0.5 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KIK68485.1 - 0.00076 19.6 0.1 0.054 13.7 0.0 2.8 3 0 0 3 3 3 1 Cold shock domain PIN_4 PF13638.6 KIK68485.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 PIN domain SAE2 PF08573.10 KIK68486.1 - 1e-05 26.6 2.5 1.7e-05 25.9 2.5 1.3 1 1 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Pkinase_fungal PF17667.1 KIK68487.1 - 2.7e-47 161.5 0.0 3.8e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK68487.1 - 3.7e-06 26.5 0.0 9.1e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3243 PF11588.8 KIK68487.1 - 0.013 15.8 0.2 0.026 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) BetaGal_dom2 PF10435.9 KIK68488.1 - 0.042 13.7 1.2 0.078 12.8 1.2 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 MFS_1 PF07690.16 KIK68489.1 - 4.3e-35 121.3 31.3 5.6e-35 120.9 31.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK68489.1 - 3.2e-07 30.0 3.9 3.2e-07 30.0 3.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Glyco_hydro_47 PF01532.20 KIK68490.1 - 6.7e-128 427.4 0.1 7.7e-128 427.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 KIK68490.1 - 0.019 14.5 0.1 0.084 12.4 0.0 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus FIST PF08495.10 KIK68490.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 FIST N domain Glyco_hydro_16 PF00722.21 KIK68491.1 - 1.4e-39 135.4 3.8 2.3e-39 134.7 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Abhydrolase_2 PF02230.16 KIK68492.1 - 2e-12 47.4 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIK68492.1 - 0.0015 19.2 0.0 0.0021 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1218 PF06749.12 KIK68493.1 - 0.042 14.4 0.2 0.053 14.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) Lustrin_cystein PF14625.6 KIK68493.1 - 0.32 11.4 7.4 0.65 10.4 7.5 1.6 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain CLIP_SPH_mas PF18398.1 KIK68494.1 - 0.0066 16.8 1.8 0.0066 16.8 1.8 2.0 2 1 0 2 2 2 1 Clip-domain serine protease homolog masquerade Lustrin_cystein PF14625.6 KIK68495.1 - 0.0054 17.1 2.4 0.0073 16.7 2.4 1.3 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Lustrin_cystein PF14625.6 KIK68497.1 - 0.017 15.5 6.4 0.024 15.0 6.4 1.4 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain FGGY_C PF02782.16 KIK68498.1 - 0.03 14.0 0.0 0.091 12.5 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain RRM_1 PF00076.22 KIK68499.1 - 5.8e-24 83.7 0.0 2.8e-12 46.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK68499.1 - 2.9e-06 27.0 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KIK68499.1 - 0.031 13.8 0.0 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK68499.1 - 0.037 14.1 0.0 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 KIK68499.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif FMO-like PF00743.19 KIK68500.1 - 1.5e-45 155.7 0.0 5.3e-34 117.5 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Syntaxin-6_N PF09177.11 KIK68500.1 - 2.6e-24 85.6 4.2 2.7e-24 85.6 0.9 2.5 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Pyr_redox_3 PF13738.6 KIK68500.1 - 1.3e-15 57.5 0.1 5.9e-11 42.2 0.0 3.4 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase SNARE PF05739.19 KIK68500.1 - 2.3e-09 37.1 0.2 5.6e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KIK68500.1 - 2.8e-05 23.9 2.1 4.9e-05 23.2 2.1 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 K_oxygenase PF13434.6 KIK68500.1 - 0.0001 21.6 0.0 0.0003 20.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK68500.1 - 0.00018 20.8 0.0 0.00099 18.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK68500.1 - 0.0004 20.4 6.0 0.023 14.7 0.1 4.4 5 0 0 5 5 5 1 FAD-NAD(P)-binding DUF3040 PF11239.8 KIK68500.1 - 0.0019 18.4 0.2 0.0044 17.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) NAD_binding_8 PF13450.6 KIK68500.1 - 0.011 15.9 2.0 0.032 14.4 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1640 PF07798.11 KIK68500.1 - 0.032 14.3 2.8 1.5 8.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Laminin_II PF06009.12 KIK68500.1 - 0.043 13.8 3.0 3.6 7.6 1.7 2.3 2 0 0 2 2 2 0 Laminin Domain II Prominin PF05478.11 KIK68500.1 - 0.1 10.6 0.3 1.1 7.1 0.0 1.8 1 1 0 2 2 2 0 Prominin Thi4 PF01946.17 KIK68500.1 - 0.12 11.6 0.3 2.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KIK68500.1 - 0.19 10.9 3.9 3.7 6.7 0.4 2.4 2 0 0 2 2 2 0 FAD binding domain HMMR_N PF15905.5 KIK68500.1 - 0.55 9.7 7.0 0.4 10.1 3.4 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PspA_IM30 PF04012.12 KIK68500.1 - 0.59 9.7 8.7 0.23 11.0 1.0 2.7 2 1 1 3 3 3 0 PspA/IM30 family DUF4140 PF13600.6 KIK68500.1 - 1.5 9.3 5.4 0.43 11.1 0.5 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fez1 PF06818.15 KIK68500.1 - 2.1 8.8 10.8 0.089 13.2 3.1 2.1 2 0 0 2 2 2 0 Fez1 DAO PF01266.24 KIK68500.1 - 2.1 7.8 5.2 9.5 5.7 0.1 3.7 4 1 1 5 5 5 0 FAD dependent oxidoreductase DUF4618 PF15397.6 KIK68500.1 - 7.4 5.9 9.1 1.1 8.7 0.5 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4618) Spc7 PF08317.11 KIK68500.1 - 9.9 4.9 9.8 1.5 7.6 2.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Chromo PF00385.24 KIK68501.1 - 7.3e-09 35.4 0.2 1.2e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KIK68501.1 - 1.2e-06 28.3 5.7 2.2e-06 27.4 5.7 1.4 1 0 0 1 1 1 1 PHD-finger SoxD PF04267.12 KIK68501.1 - 0.21 11.7 1.7 0.31 11.2 0.2 2.0 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family DPBB_1 PF03330.18 KIK68502.1 - 4.7e-10 39.6 0.2 8.2e-10 38.8 0.2 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIK68502.1 - 3e-05 23.8 0.3 4.5e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 Barwin family Gal_Lectin PF02140.18 KIK68502.1 - 0.054 13.9 0.2 0.086 13.3 0.2 1.3 1 0 0 1 1 1 0 Galactose binding lectin domain Dus PF01207.17 KIK68503.1 - 9.1e-55 185.9 0.0 1e-54 185.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KIK68503.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Metallophos PF00149.28 KIK68505.1 - 4.4e-16 60.0 0.4 6.2e-16 59.5 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_12 PF13424.6 KIK68506.1 - 3.6e-06 27.2 3.1 7.6e-06 26.1 0.7 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK68506.1 - 5.2e-05 22.8 0.2 7.3e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 KIK68506.1 - 0.00021 21.7 0.6 0.00021 21.7 0.6 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK68506.1 - 0.00032 20.4 0.1 0.00032 20.4 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK68506.1 - 0.0007 19.6 5.1 0.0016 18.5 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68506.1 - 0.00092 19.1 0.1 0.00092 19.1 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK68506.1 - 0.001 19.3 1.8 0.021 15.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK68506.1 - 0.002 18.8 0.5 0.002 18.8 0.5 4.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68506.1 - 0.0032 17.4 0.4 0.0032 17.4 0.4 2.4 3 0 0 3 3 1 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KIK68506.1 - 0.013 15.4 0.2 0.033 14.1 0.1 1.7 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_4 PF07721.14 KIK68506.1 - 0.049 14.3 0.1 0.049 14.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK68506.1 - 0.056 13.7 3.8 0.058 13.6 0.8 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK68506.1 - 0.069 13.8 0.5 0.069 13.8 0.5 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK68506.1 - 0.079 13.3 0.3 0.079 13.3 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK68506.1 - 0.27 11.9 12.5 0.2 12.3 0.8 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK68506.1 - 1.3 9.0 4.7 0.72 9.8 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat p450 PF00067.22 KIK68507.1 - 5.4e-62 210.0 0.2 1.8e-61 208.3 0.2 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF202 PF02656.15 KIK68508.1 - 2.5e-17 63.1 0.2 2.5e-17 63.1 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) 7tm_1 PF00001.21 KIK68508.1 - 0.045 13.1 3.5 0.061 12.6 3.5 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) E1-E2_ATPase PF00122.20 KIK68508.1 - 0.063 12.8 3.8 0.089 12.3 3.8 1.2 1 0 0 1 1 1 0 E1-E2 ATPase DUF4418 PF14387.6 KIK68508.1 - 1 9.6 7.2 6.3 7.0 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) XPG_I PF00867.18 KIK68509.1 - 2.7e-14 53.3 0.0 6.9e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK68509.1 - 5e-06 26.9 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain CR6_interact PF10147.9 KIK68509.1 - 0.021 14.5 2.3 0.39 10.4 0.0 2.5 3 0 0 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 5_3_exonuc PF01367.20 KIK68509.1 - 0.17 12.5 0.0 0.97 10.1 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Glyco_hydro_15 PF00723.21 KIK68510.1 - 6.4e-57 193.3 0.0 9.6e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GGA_N-GAT PF18308.1 KIK68511.1 - 0.052 13.2 0.2 0.097 12.3 0.2 1.4 1 0 0 1 1 1 0 GGA N-GAT domain LEA_2 PF03168.13 KIK68513.1 - 1e-05 26.0 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KIK68513.1 - 0.1 11.9 0.7 0.15 11.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Peptidase_S41 PF03572.18 KIK68514.1 - 1.1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Peptidase_C14 PF00656.22 KIK68515.1 - 3.4e-36 125.4 0.0 6.3e-36 124.6 0.0 1.4 1 1 0 1 1 1 1 Caspase domain BBE PF08031.12 KIK68516.1 - 0.00046 20.2 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like CBP PF12192.8 KIK68518.1 - 0.00062 19.9 8.0 0.00084 19.5 8.0 1.2 1 0 0 1 1 1 1 Fungal calcium binding protein BTB PF00651.31 KIK68519.1 - 0.0017 18.6 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Vanabin-2 PF11437.8 KIK68520.1 - 0.15 12.2 6.0 0.31 11.2 6.0 1.6 1 1 0 1 1 1 0 Vanadium-binding protein 2 zf-LYAR PF08790.11 KIK68520.1 - 1.9 8.5 4.9 4.5 7.3 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Coatomer_WDAD PF04053.14 KIK68521.1 - 1.6e-135 452.7 0.0 2.3e-135 452.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KIK68521.1 - 2.5e-111 372.3 0.0 3.3e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KIK68521.1 - 5.8e-44 147.2 13.3 6.6e-07 29.9 0.2 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68521.1 - 1e-11 44.9 0.1 0.01 16.1 0.0 5.7 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK68521.1 - 0.023 13.4 1.4 1.2 7.7 0.3 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 KIK68521.1 - 4.7 8.3 4.9 1.1e+02 4.0 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.26 KIK68523.1 - 0.059 13.5 4.0 0.25 11.5 0.1 2.7 3 0 0 3 3 3 0 WW domain Pyr_redox_3 PF13738.6 KIK68524.1 - 1.5e-19 70.4 0.0 3e-17 62.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK68524.1 - 8e-19 67.5 0.0 7.2e-16 57.7 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK68524.1 - 8.6e-13 48.2 0.0 4e-10 39.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK68524.1 - 4.4e-08 32.6 0.1 9.5e-06 25.0 0.1 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK68524.1 - 0.00051 20.5 0.0 0.14 12.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK68524.1 - 0.0012 18.5 0.0 0.51 9.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK68524.1 - 0.0036 17.5 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK68524.1 - 0.012 15.0 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK68524.1 - 0.051 12.8 0.1 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KIK68524.1 - 0.079 12.8 0.1 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIK68524.1 - 0.085 11.9 0.1 0.42 9.6 0.0 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF2842 PF11003.8 KIK68525.1 - 3.2 8.1 9.8 9.3 6.6 9.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) DUF308 PF03729.13 KIK68528.1 - 0.015 15.6 1.0 0.015 15.6 1.0 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF1418 PF07214.12 KIK68528.1 - 0.12 12.2 1.0 0.2 11.5 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) WD40 PF00400.32 KIK68529.1 - 2.2e-39 132.7 22.7 6.8e-07 29.9 1.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68529.1 - 5e-23 81.2 0.5 0.0012 19.1 0.0 6.8 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK68529.1 - 4.5e-08 33.2 1.0 0.15 11.9 0.0 3.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK68529.1 - 3.3e-07 29.6 0.7 0.039 12.9 0.1 3.8 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK68529.1 - 0.00041 19.2 1.1 4.7 5.8 0.0 3.8 2 2 2 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.6 KIK68529.1 - 0.019 14.3 0.4 7.9 5.7 0.0 3.6 2 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 KIK68529.1 - 0.14 10.1 0.0 0.27 9.2 0.0 1.4 1 0 0 1 1 1 0 IKI3 family PCI PF01399.27 KIK68530.1 - 2.8e-21 76.0 0.0 2.8e-21 76.0 0.0 2.6 4 0 0 4 4 4 1 PCI domain Rpn3_C PF08375.11 KIK68530.1 - 8e-20 71.0 0.4 8e-20 71.0 0.4 2.6 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 KIK68530.1 - 0.025 14.7 5.7 0.033 14.3 0.8 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 KIK68530.1 - 0.029 13.8 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 SAC3/GANP family ATP-synt_10 PF05176.14 KIK68530.1 - 0.11 11.7 0.0 0.33 10.2 0.0 1.7 1 0 0 1 1 1 0 ATP10 protein TPR_12 PF13424.6 KIK68530.1 - 0.82 10.0 5.9 3 8.2 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NDUFA12 PF05071.16 KIK68531.1 - 1.1e-09 39.0 0.5 1.8e-09 38.3 0.5 1.6 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4621 PF15414.6 KIK68532.1 - 0.075 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) Big_11 PF18200.1 KIK68532.1 - 0.17 11.8 0.1 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain RRM_1 PF00076.22 KIK68533.1 - 1.4e-32 111.3 0.0 1e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 KIK68534.1 - 3.3e-46 157.2 0.0 6e-28 98.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK68534.1 - 1.4e-42 146.3 28.3 9.9e-26 91.0 9.5 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK68534.1 - 8.8e-09 35.1 0.3 0.0021 17.5 0.4 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK68534.1 - 0.00034 20.3 0.6 0.14 11.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK68534.1 - 0.00073 19.8 0.1 1.9 8.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KIK68534.1 - 0.012 14.7 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KIK68534.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KIK68534.1 - 0.017 15.6 0.5 6.6 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK68534.1 - 0.031 14.7 0.0 3.5 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KIK68534.1 - 0.036 13.7 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK68534.1 - 0.044 13.0 0.2 1.6 7.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ATPase PF06745.13 KIK68534.1 - 0.048 13.0 0.2 7.7 5.8 0.0 2.5 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 KIK68534.1 - 0.072 12.4 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KIK68534.1 - 0.073 13.1 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK68534.1 - 0.088 12.7 0.0 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KIK68534.1 - 0.098 12.6 0.8 13 5.6 0.2 2.8 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KIK68534.1 - 0.15 11.6 1.0 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KIK68534.1 - 0.16 11.7 0.1 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIK68534.1 - 0.18 10.7 0.3 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pro_isomerase PF00160.21 KIK68535.1 - 1.6e-47 161.7 0.3 1.8e-47 161.6 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.22 KIK68536.1 - 1.5e-72 244.8 0.0 1.8e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_40 PF14493.6 KIK68536.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_11 PF08241.12 KIK68537.1 - 2.4e-21 76.2 0.1 5.1e-21 75.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK68537.1 - 1.5e-18 67.3 0.0 2.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK68537.1 - 7.1e-13 49.1 0.0 1.1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK68537.1 - 1.3e-11 44.6 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK68537.1 - 1.9e-08 33.9 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIK68537.1 - 5.9e-07 29.5 0.0 1e-06 28.7 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIK68537.1 - 0.0034 17.3 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase DUF3419 PF11899.8 KIK68537.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_4 PF02390.17 KIK68537.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase NodS PF05401.11 KIK68537.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Umbravirus_LDM PF04817.12 KIK68538.1 - 0.046 13.1 1.3 6.2 6.1 0.1 2.9 1 1 2 3 3 3 0 Umbravirus long distance movement (LDM) family SMC_N PF02463.19 KIK68539.1 - 4.5e-68 229.0 19.7 1.4e-67 227.4 19.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIK68539.1 - 3.4e-23 82.2 0.0 9.7e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIK68539.1 - 1.3e-13 51.5 2.7 5e-06 26.5 0.1 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK68539.1 - 2.2e-12 47.9 6.6 2.2e-12 47.9 6.6 7.7 4 2 2 6 6 6 1 AAA domain AAA_15 PF13175.6 KIK68539.1 - 3e-07 30.5 13.4 3e-07 30.5 13.4 4.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KIK68539.1 - 1.2e-05 24.9 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FlaC_arch PF05377.11 KIK68539.1 - 0.0028 18.0 0.4 0.0028 18.0 0.4 6.9 8 0 0 8 8 8 2 Flagella accessory protein C (FlaC) ABC_tran PF00005.27 KIK68539.1 - 0.86 10.1 0.0 0.86 10.1 0.0 5.8 4 2 0 4 4 4 0 ABC transporter Laminin_II PF06009.12 KIK68539.1 - 6.2 6.8 58.7 0.057 13.4 2.6 7.7 2 2 5 7 7 7 0 Laminin Domain II PAN_1 PF00024.26 KIK68540.1 - 0.017 15.1 0.2 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 KIK68540.1 - 0.23 11.4 2.4 0.23 11.4 0.4 2.1 2 1 0 2 2 2 0 PAN domain Ank PF00023.30 KIK68541.1 - 2.4e-11 43.5 0.4 8.5e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIK68541.1 - 1.4e-10 41.2 0.7 4.4e-06 26.9 0.5 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK68541.1 - 6.4e-10 39.4 0.2 3.5e-06 27.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK68541.1 - 1e-09 37.8 0.2 2.6e-05 24.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KIK68541.1 - 2.9e-09 37.4 0.0 4.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase PF00069.25 KIK68542.1 - 1.9e-40 138.9 0.0 2e-39 135.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68542.1 - 2.3e-20 73.0 0.0 4.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK68542.1 - 8.9e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK68542.1 - 0.0085 15.5 0.3 0.018 14.4 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK68542.1 - 0.023 14.6 0.1 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 KIK68545.1 - 7.9e-15 55.9 0.9 1.4e-14 55.1 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SPATA6 PF14909.6 KIK68545.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 GMC_oxred_N PF00732.19 KIK68546.1 - 2.2e-35 122.5 0.0 3.5e-35 121.8 0.0 1.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK68546.1 - 8.8e-26 91.2 0.0 1.5e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KIK68546.1 - 0.0013 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK68546.1 - 0.002 18.3 0.4 0.0046 17.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK68546.1 - 0.011 15.0 0.1 3 7.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK68546.1 - 0.032 13.3 0.6 0.054 12.6 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KIK68546.1 - 0.033 13.2 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KIK68546.1 - 0.23 10.7 0.3 0.43 9.8 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_1 PF00561.20 KIK68547.1 - 2.2e-14 53.8 0.2 1.1e-10 41.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68547.1 - 4.3e-10 40.6 0.2 6.1e-10 40.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KIK68547.1 - 5.8e-06 26.4 0.0 8.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KIK68547.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KIK68547.1 - 0.00025 20.7 0.1 0.0004 20.0 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIK68547.1 - 0.031 13.7 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ndr PF03096.14 KIK68547.1 - 0.14 10.8 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family F-box-like PF12937.7 KIK68548.1 - 0.00045 20.1 2.1 0.00066 19.5 0.4 2.3 2 0 0 2 2 2 1 F-box-like ADH_zinc_N PF00107.26 KIK68550.1 - 3.6e-21 75.5 0.1 6.9e-21 74.6 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK68550.1 - 3.6e-15 55.8 0.0 6.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIK68550.1 - 4.6e-08 34.2 0.0 7.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK68550.1 - 0.0094 16.2 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain ADC PF06314.11 KIK68551.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Histone PF00125.24 KIK68552.1 - 1.6e-22 80.3 1.5 2.1e-22 79.9 1.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK68552.1 - 3.4e-05 24.0 0.1 7.9e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIK68552.1 - 0.00028 21.3 0.0 0.0005 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIK68552.1 - 0.044 13.8 0.3 0.054 13.5 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 KIK68553.1 - 5.5e-18 65.6 0.0 6.9e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK68553.1 - 2.8e-16 58.9 0.6 5.5e-16 58.0 0.6 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK68553.1 - 1.4e-06 28.5 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RhlB PF12300.8 KIK68553.1 - 0.0039 17.3 1.3 0.0053 16.9 1.3 1.1 1 0 0 1 1 1 1 ATP-dependent RNA helicase RhlB DUF202 PF02656.15 KIK68554.1 - 4.3e-15 55.9 0.1 4.3e-15 55.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CRPA PF05745.11 KIK68554.1 - 0.22 11.5 2.4 0.24 11.4 1.6 1.4 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Homoserine_dh PF00742.19 KIK68555.1 - 5.3e-50 169.7 0.0 6.9e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KIK68555.1 - 1.3e-16 61.3 0.0 2.7e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NCE101 PF11654.8 KIK68555.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 FOXP-CC PF16159.5 KIK68556.1 - 0.0069 17.0 2.6 0.26 12.0 0.1 2.6 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIK68556.1 - 0.029 15.2 9.8 0.87 10.6 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KIK68556.1 - 0.24 11.7 6.7 0.45 10.8 0.1 3.1 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF5527 PF17665.1 KIK68559.1 - 0.058 12.9 0.2 0.093 12.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) 2-oxoacid_dh PF00198.23 KIK68560.1 - 1.7e-82 276.4 0.1 2.4e-82 275.9 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK68560.1 - 8.1e-20 70.4 1.3 1.5e-19 69.6 1.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KIK68560.1 - 2.7e-05 24.8 0.2 0.047 14.4 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KIK68560.1 - 4.8e-05 23.1 0.0 0.00057 19.7 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 KIK68560.1 - 0.0019 18.1 0.4 0.004 17.0 0.4 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KIK68560.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain YL1 PF05764.13 KIK68560.1 - 0.07 13.2 15.1 0.1 12.7 15.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2052 PF09747.9 KIK68560.1 - 0.81 9.8 9.6 1.2 9.2 9.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 KIK68560.1 - 1.1 9.1 12.2 1.4 8.6 12.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 KIK68560.1 - 1.3 8.9 16.3 2.1 8.2 16.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 KIK68560.1 - 1.4 7.6 7.8 2.3 6.9 7.8 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KIK68560.1 - 2.4 6.3 8.9 3 6.0 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM76 PF16046.5 KIK68560.1 - 3.8 6.8 7.7 6.6 6.0 7.7 1.3 1 0 0 1 1 1 0 FAM76 protein Ndc1_Nup PF09531.10 KIK68560.1 - 5.7 5.5 9.9 8.1 5.0 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BNR PF02012.20 KIK68561.1 - 0.00026 20.5 2.3 0.65 10.2 0.3 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_2 PF13088.6 KIK68561.1 - 0.00031 20.1 0.0 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KIK68561.1 - 0.004 16.0 0.0 0.7 8.6 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, PCI PF01399.27 KIK68564.1 - 0.001 19.5 0.1 0.0039 17.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KIK68564.1 - 0.15 12.2 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box PF00646.33 KIK68565.1 - 7.9e-06 25.6 0.6 7.9e-06 25.6 0.6 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK68565.1 - 9.7e-05 22.2 0.2 0.00026 20.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK68566.1 - 3.6e-09 36.4 1.1 1.4e-08 34.5 1.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIK68566.1 - 0.65 9.8 7.8 9.7 6.0 0.1 4.9 7 0 0 7 7 7 0 Leucine rich repeat Ribophorin_II PF05817.14 KIK68567.1 - 1.3e-32 113.2 0.0 1.6e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ADH_zinc_N PF00107.26 KIK68569.1 - 2.5e-21 76.0 0.0 3.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK68569.1 - 1.6e-20 73.0 0.0 3.7e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIK68569.1 - 2e-07 32.1 0.0 4.6e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK68569.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1707 PF08044.11 KIK68569.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) ADH_zinc_N PF00107.26 KIK68570.1 - 6e-22 78.0 0.0 9.5e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK68570.1 - 9.3e-15 54.5 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIK68570.1 - 1.1e-08 36.2 0.0 2.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK68570.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1707 PF08044.11 KIK68570.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) HECT_2 PF09814.9 KIK68571.1 - 4.3e-49 167.4 0.0 6.5e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SKN1 PF03935.15 KIK68572.1 - 9.4e-190 631.3 1.9 1.2e-189 630.9 1.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sugar_tr PF00083.24 KIK68574.1 - 3e-38 131.9 13.8 4.2e-38 131.4 13.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK68574.1 - 3e-34 118.5 30.1 3.5e-34 118.3 29.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 KIK68574.1 - 0.34 9.6 7.6 0.23 10.2 5.6 1.7 1 1 1 2 2 2 0 LacY proton/sugar symporter PPTA PF01239.22 KIK68575.1 - 1.5e-39 132.6 14.9 2.1e-08 33.6 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 KIK68575.1 - 0.023 14.7 1.1 0.029 14.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) TPR_17 PF13431.6 KIK68575.1 - 0.19 12.2 1.6 13 6.4 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Retrotran_gag_3 PF14244.6 KIK68575.1 - 0.33 10.8 1.5 5 7.0 0.1 3.0 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type FoP_duplication PF13865.6 KIK68576.1 - 1.6e-08 35.0 0.1 2e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KIK68577.1 - 3.6e-14 52.3 0.0 4.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK68577.1 - 0.0087 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RNA_pol_3_Rpc31 PF11705.8 KIK68578.1 - 6.4e-28 98.5 8.0 8.2e-28 98.2 8.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cnd2 PF05786.14 KIK68578.1 - 0.095 11.4 5.2 0.11 11.1 5.2 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2371 PF10177.9 KIK68579.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF3262 PF11660.8 KIK68579.1 - 0.3 11.5 11.7 0.88 10.0 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3262) DUF1282 PF06930.12 KIK68579.1 - 0.49 10.1 5.3 0.86 9.4 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1282) AAA-ATPase_like PF09820.9 KIK68580.1 - 1.1e-08 34.9 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase AAA-ATPase_like PF09820.9 KIK68581.1 - 0.00037 20.0 0.0 0.00043 19.8 0.0 1.0 1 0 0 1 1 1 1 Predicted AAA-ATPase Zap1_zf2 PF18217.1 KIK68581.1 - 0.043 13.8 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 Zap1 zinc finger 2 tRNA_U5-meth_tr PF05958.11 KIK68582.1 - 2.4e-13 49.8 0.0 2.8e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KIK68582.1 - 1.7e-07 31.0 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KIK68582.1 - 7.7e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK68582.1 - 0.0001 22.9 0.0 0.00033 21.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIK68582.1 - 0.00092 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KIK68582.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KIK68582.1 - 0.0054 17.3 0.0 0.017 15.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK68582.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KIK68582.1 - 0.062 13.3 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KIK68582.1 - 0.069 12.8 0.1 9.2 5.9 0.0 3.0 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 KIK68582.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LysM PF01476.20 KIK68583.1 - 5e-09 36.1 0.0 9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain Bul1_C PF04426.12 KIK68584.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Bul1 C terminus F-box-like PF12937.7 KIK68585.1 - 5.7e-08 32.5 2.5 1.8e-07 30.9 2.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK68585.1 - 1.8e-05 24.5 6.6 1.9e-05 24.4 4.4 2.3 2 0 0 2 2 2 1 F-box domain GRAB PF10375.9 KIK68586.1 - 9.7e-08 31.6 1.7 1.8e-07 30.7 1.7 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 KIK68586.1 - 0.0085 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 GRIP domain GldM_N PF12081.8 KIK68586.1 - 0.024 14.8 17.1 0.079 13.0 3.0 2.5 1 1 1 2 2 2 0 GldM N-terminal domain DUF1298 PF06974.13 KIK68586.1 - 0.25 11.3 1.6 13 5.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1298) DUF3713 PF12506.8 KIK68586.1 - 0.44 10.9 9.6 4.1 7.7 2.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) CENP-F_leu_zip PF10473.9 KIK68586.1 - 2.9 7.9 51.0 0.17 11.9 3.5 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGAP_C PF03836.15 KIK68586.1 - 3.6 7.7 19.3 0.3 11.2 5.1 2.6 2 0 0 2 2 2 0 RasGAP C-terminus LPP PF04728.13 KIK68586.1 - 6.5 7.2 7.3 1.3 9.4 1.5 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KIK68586.1 - 8.1 6.5 17.3 8.2 6.5 3.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cys_Met_Meta_PP PF01053.20 KIK68588.1 - 1e-22 80.2 0.0 1.3e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK68588.1 - 0.0068 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II CNH PF00780.22 KIK68589.1 - 4.2e-10 39.7 0.0 9.8e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 CNH domain CBS PF00571.28 KIK68590.1 - 3.3e-20 72.3 1.3 9.1e-05 22.8 0.0 4.6 4 1 0 4 4 4 4 CBS domain XRCC4 PF06632.12 KIK68590.1 - 0.071 12.0 2.3 0.1 11.4 2.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Glyco_hydro_39 PF01229.17 KIK68591.1 - 4.1e-48 164.2 0.0 7.1e-48 163.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 DUF4334 PF14232.6 KIK68591.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) WD40 PF00400.32 KIK68593.1 - 0.00075 20.3 6.7 0.99 10.4 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat IKI3 PF04762.12 KIK68593.1 - 0.17 9.8 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 IKI3 family AKAP7_NLS PF10469.9 KIK68595.1 - 2.1e-12 47.4 0.0 4e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KIK68595.1 - 0.0045 16.9 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Methyltransf_25 PF13649.6 KIK68597.1 - 7.3e-05 23.4 0.0 0.0059 17.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIK68597.1 - 0.0095 16.7 0.1 0.56 11.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK68597.1 - 0.031 14.9 0.0 0.083 13.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.22 KIK68598.1 - 1.4e-160 534.8 0.4 1.6e-160 534.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_inhib PF16857.5 KIK68598.1 - 0.59 10.0 2.1 4.2 7.3 0.3 2.9 3 0 0 3 3 3 0 RNA polymerase inhibitor Myb_DNA-bind_3 PF12776.7 KIK68599.1 - 0.88 10.6 3.5 1.7 9.7 1.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rotamase_3 PF13616.6 KIK68601.1 - 1.7e-19 70.4 0.0 3.5e-19 69.5 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KIK68601.1 - 1.1e-15 58.4 0.2 2.6e-15 57.2 0.2 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KIK68601.1 - 0.00061 20.6 2.0 0.0032 18.3 2.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain p450 PF00067.22 KIK68602.1 - 9.8e-63 212.5 0.0 1.2e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 KIK68603.1 - 1e-32 113.5 0.1 1.5e-17 64.4 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KIK68603.1 - 4.6e-14 52.0 4.5 1.1e-13 50.8 4.5 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KIK68603.1 - 2.7e-10 40.0 4.8 0.0048 16.4 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK68603.1 - 3.7e-10 40.1 4.1 0.13 12.0 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 KIK68603.1 - 1.9e-06 27.4 4.0 1.9e-06 27.4 4.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 KIK68603.1 - 1.9e-05 25.1 0.0 0.27 11.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KIK68603.1 - 2.1e-05 25.0 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIK68603.1 - 3.2e-05 23.9 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 KIK68603.1 - 0.00015 21.7 2.2 0.00015 21.7 2.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 KIK68603.1 - 0.00015 21.6 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK68603.1 - 0.00025 21.3 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK68603.1 - 0.0003 21.0 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK68603.1 - 0.00039 20.4 1.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KIK68603.1 - 0.0004 20.1 0.2 0.72 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KIK68603.1 - 0.0014 18.4 0.2 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK68603.1 - 0.0016 18.0 0.3 0.046 13.2 0.1 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 KIK68603.1 - 0.0019 18.4 0.0 0.8 10.0 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KIK68603.1 - 0.0021 18.4 0.0 2.3 8.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KIK68603.1 - 0.003 17.5 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 KIK68603.1 - 0.0044 16.7 1.9 0.87 9.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 KIK68603.1 - 0.0045 17.5 1.6 0.0045 17.5 1.6 2.3 1 1 2 3 3 3 1 4Fe-4S dicluster domain TsaE PF02367.17 KIK68603.1 - 0.0052 16.8 0.1 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_10 PF13237.6 KIK68603.1 - 0.0053 16.8 14.9 0.0089 16.1 1.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain NB-ARC PF00931.22 KIK68603.1 - 0.0064 15.7 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_21 PF14697.6 KIK68603.1 - 0.0064 16.6 12.1 0.013 15.6 12.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIK68603.1 - 0.0079 16.3 11.7 0.016 15.4 11.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIK68603.1 - 0.0079 16.2 0.9 0.0079 16.2 0.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_28 PF13521.6 KIK68603.1 - 0.011 15.9 0.3 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK68603.1 - 0.015 15.5 0.9 0.071 13.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KIK68603.1 - 0.019 15.5 0.3 4 8.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 KIK68603.1 - 0.028 15.3 0.4 0.028 15.3 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 KIK68603.1 - 0.036 14.6 0.2 0.036 14.6 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.14 KIK68603.1 - 0.057 13.4 2.4 0.98 9.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KIK68603.1 - 0.063 13.3 0.6 13 5.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KIK68603.1 - 0.063 13.4 0.6 7.5 6.7 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KIK68603.1 - 0.065 12.9 0.4 7 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 KIK68603.1 - 0.068 12.9 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Thymidylate_kin PF02223.17 KIK68603.1 - 0.089 12.5 0.2 5 6.8 0.0 2.7 3 0 0 3 3 3 0 Thymidylate kinase Fer4_8 PF13183.6 KIK68603.1 - 0.18 12.3 0.2 0.18 12.3 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_23 PF13476.6 KIK68603.1 - 0.37 11.3 8.8 0.31 11.5 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KIK68603.1 - 0.63 8.6 0.0 0.63 8.6 0.0 2.0 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KIK68603.1 - 0.99 9.3 2.8 52 3.7 0.1 3.3 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 KIK68603.1 - 1.5 9.5 14.6 0.38 11.4 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KIK68603.1 - 6.5 7.4 7.4 6.1 7.5 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CLTH PF10607.9 KIK68605.1 - 1.6e-33 115.7 0.4 2.7e-33 115.0 0.4 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.15 KIK68605.1 - 0.032 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain Cellsynth_D PF03500.13 KIK68605.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Cellulose synthase subunit D Phg_2220_C PF09524.10 KIK68605.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) HlyIII PF03006.20 KIK68606.1 - 1.1e-56 192.1 28.5 1.3e-56 191.8 28.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related p450 PF00067.22 KIK68607.1 - 1.4e-32 113.1 0.0 1.8e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Neugrin PF06413.11 KIK68608.1 - 4.8e-10 39.8 0.9 5.1e-10 39.7 0.9 1.0 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KIK68608.1 - 0.0013 19.0 3.7 0.0015 18.7 3.5 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_23 PF13384.6 KIK68608.1 - 0.0021 17.8 0.5 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Cid2 PF09774.9 KIK68608.1 - 0.021 15.2 0.7 0.024 15.1 0.7 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DDE_5 PF13546.6 KIK68608.1 - 0.042 13.2 0.4 0.074 12.4 0.3 1.4 1 1 1 2 2 2 0 DDE superfamily endonuclease MarR_2 PF12802.7 KIK68608.1 - 0.07 13.0 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 MarR family FeoC PF09012.10 KIK68608.1 - 0.11 12.6 0.2 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Integrase_Zn PF02022.19 KIK68608.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain Cofilin_ADF PF00241.20 KIK68609.1 - 2.9e-24 85.2 0.2 3.7e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cas9_Topo PF17894.1 KIK68609.1 - 0.011 15.8 0.2 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Acetyltransf_1 PF00583.25 KIK68610.1 - 2.2e-16 60.1 0.0 2.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK68610.1 - 8.2e-08 32.2 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK68610.1 - 6.6e-06 26.5 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK68610.1 - 0.00066 20.4 0.0 0.00081 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK68610.1 - 0.0059 16.8 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAC PF01849.18 KIK68611.1 - 1.3e-24 85.9 0.1 2.2e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 NAC domain HAMP PF00672.25 KIK68611.1 - 0.012 16.0 0.5 0.022 15.1 0.1 1.6 2 0 0 2 2 2 0 HAMP domain RabGAP-TBC PF00566.18 KIK68613.1 - 6.9e-19 68.3 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AMP-binding PF00501.28 KIK68614.1 - 9.9e-88 294.5 0.0 1.3e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK68614.1 - 6.7e-11 43.0 0.3 1.2e-10 42.2 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CsbD PF05532.12 KIK68616.1 - 8.8e-14 51.2 11.1 1.6e-08 34.3 1.4 2.1 1 1 1 2 2 2 2 CsbD-like FAD_binding_3 PF01494.19 KIK68617.1 - 1.3e-10 41.1 1.6 5.1e-07 29.3 0.2 3.2 2 2 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KIK68617.1 - 4.1e-07 30.1 0.1 1.5e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK68617.1 - 4.5e-05 23.2 0.0 9.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK68617.1 - 5e-05 22.6 0.0 9.9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KIK68617.1 - 0.00078 18.8 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.16 KIK68617.1 - 0.0034 17.1 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIK68617.1 - 0.0067 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK68617.1 - 0.027 13.7 0.1 0.067 12.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK68617.1 - 0.037 13.3 0.1 0.08 12.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 KIK68617.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIK68617.1 - 0.062 12.0 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KIK68617.1 - 0.084 13.4 0.1 0.23 12.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIK68617.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_20 PF00982.21 KIK68618.1 - 5.5e-131 437.5 0.0 1.2e-115 386.9 0.0 3.1 2 1 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIK68618.1 - 4.7e-63 212.4 0.0 8e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KIK68618.1 - 0.75 9.4 3.1 0.39 10.4 0.5 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Zn_clus PF00172.18 KIK68619.1 - 0.0037 17.4 15.2 0.0057 16.8 15.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIK68620.1 - 1e-06 28.7 8.6 1e-06 28.7 8.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAM33 PF02330.16 KIK68621.1 - 7.8e-67 225.3 0.4 9e-67 225.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein MFS_5 PF05631.14 KIK68623.1 - 3.4e-69 233.5 6.6 6.1e-69 232.6 6.6 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KIK68623.1 - 6.4e-19 68.1 28.0 6.4e-19 68.1 28.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4044 PF13253.6 KIK68623.1 - 0.18 11.4 0.9 0.48 10.0 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) DUF3455 PF11937.8 KIK68624.1 - 2.3e-25 89.8 0.1 3.2e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KIK68624.1 - 2 8.7 7.1 5.3 7.3 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2990) Oxidored_FMN PF00724.20 KIK68626.1 - 6.9e-25 88.0 0.0 1.7e-24 86.8 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.7 KIK68627.1 - 0.023 14.6 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 KIK68627.1 - 0.19 11.8 12.3 0.44 10.7 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich repeat Aldo_ket_red PF00248.21 KIK68628.1 - 2.4e-59 201.0 0.0 2.7e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_syn_2C PF08485.10 KIK68628.1 - 0.12 12.1 0.3 0.29 10.9 0.3 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal TFIIE_alpha PF02002.17 KIK68629.1 - 6.2e-14 51.7 1.2 1.3e-13 50.7 0.2 2.1 3 0 0 3 3 3 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KIK68629.1 - 2.3e-06 27.8 5.5 1.7e-05 25.0 5.6 2.3 1 1 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KIK68629.1 - 8.7e-05 22.0 3.1 0.00017 21.0 3.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding CbiG_mid PF11761.8 KIK68629.1 - 0.039 14.1 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis central region DcrB PF08786.11 KIK68629.1 - 0.054 13.6 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 DcrB YppF PF14178.6 KIK68629.1 - 0.061 13.2 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 YppF-like protein RecO_N_2 PF13114.6 KIK68629.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 RecO N terminal Glyco_hydro_53 PF07745.13 KIK68630.1 - 4.5e-84 282.3 0.0 5.2e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 MtrE PF04206.12 KIK68631.1 - 0.1 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E MFS_1 PF07690.16 KIK68632.1 - 2.6e-35 122.0 41.3 2.6e-35 122.0 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK68632.1 - 1.5e-10 40.6 32.3 5.2e-10 38.8 32.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK68632.1 - 0.00071 18.1 1.8 0.00071 18.1 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SRP54 PF00448.22 KIK68633.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Bestrophin PF01062.21 KIK68635.1 - 6.3e-33 114.4 0.1 2.9e-18 66.3 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel UQ_con PF00179.26 KIK68638.1 - 1.5e-48 164.0 0.0 1.7e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK68638.1 - 0.0048 17.2 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIK68638.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KIK68638.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyco_hydro_16 PF00722.21 KIK68640.1 - 5.9e-09 35.6 0.0 2.6e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Nup96 PF12110.8 KIK68642.1 - 7.3e-74 248.5 0.0 4.7e-72 242.6 0.0 2.3 1 1 0 1 1 1 1 Nuclear protein 96 Arabino_trans_C PF14896.6 KIK68642.1 - 0.08 11.9 2.9 0.12 11.3 2.9 1.2 1 0 0 1 1 1 0 EmbC C-terminal domain SDA1 PF05285.12 KIK68642.1 - 0.59 9.5 22.9 0.87 9.0 22.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK68642.1 - 1.2 7.3 25.3 2 6.5 25.3 1.3 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 KIK68642.1 - 1.4 9.1 14.8 2.4 8.3 14.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CPSF100_C PF13299.6 KIK68642.1 - 1.8 8.7 6.7 4.5 7.4 6.7 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 KIK68642.1 - 1.8 6.7 16.8 2.7 6.2 16.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 KIK68642.1 - 3 7.6 15.0 7.1 6.4 15.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRN3 PF05327.11 KIK68642.1 - 4.2 5.8 13.1 6.6 5.1 13.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PI3K_1B_p101 PF10486.9 KIK68642.1 - 4.6 4.9 6.0 6.7 4.4 6.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RP-C_C PF11800.8 KIK68642.1 - 5.2 7.1 7.9 0.93 9.5 3.4 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region GST_N_2 PF13409.6 KIK68643.1 - 1e-23 83.4 0.1 3.4e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK68643.1 - 2.5e-15 56.2 0.0 4.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK68643.1 - 4.6e-08 33.2 0.0 8.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK68643.1 - 3.4e-05 24.1 0.2 0.00067 20.0 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK68643.1 - 0.0046 17.1 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_C57 PF03290.13 KIK68643.1 - 0.14 10.9 0.3 0.2 10.4 0.3 1.2 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Mem_trans PF03547.18 KIK68644.1 - 7.9e-35 120.0 7.6 1.3e-29 102.8 1.4 2.9 2 1 0 2 2 2 2 Membrane transport protein MBR1 PF17058.5 KIK68644.1 - 0.064 13.6 0.9 0.11 12.8 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 YhhN PF07947.14 KIK68644.1 - 0.13 11.9 11.6 0.085 12.5 6.3 2.5 2 0 0 2 2 2 0 YhhN family DUF4750 PF15938.5 KIK68644.1 - 4.6 7.0 7.3 0.22 11.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) MAPEG PF01124.18 KIK68645.1 - 3.7e-17 62.4 0.1 4.3e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 MAPEG family FAD_binding_3 PF01494.19 KIK68646.1 - 9.5e-68 229.0 0.0 1.1e-67 228.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIK68646.1 - 4.7e-09 36.5 0.0 1.7e-07 31.4 0.0 2.4 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.14 KIK68646.1 - 1.4e-05 24.2 0.0 0.0012 17.8 0.0 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK68646.1 - 4.8e-05 22.7 0.0 0.00048 19.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK68646.1 - 0.00011 21.9 0.0 0.00028 20.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK68646.1 - 0.0016 17.5 0.0 0.0038 16.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KIK68646.1 - 0.0031 18.0 0.0 0.0077 16.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK68646.1 - 0.01 14.6 0.0 0.058 12.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KIK68646.1 - 0.029 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KIK68646.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KIK68646.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIK68646.1 - 0.076 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KIK68646.1 - 0.077 12.2 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK68646.1 - 0.094 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KIK68646.1 - 0.12 12.6 0.4 1 9.6 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain Cnd1 PF12717.7 KIK68647.1 - 2.6e-59 199.9 2.7 2.6e-51 173.9 0.1 4.2 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KIK68647.1 - 5.9e-49 166.1 9.0 2e-48 164.4 0.0 4.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 KIK68647.1 - 1.1e-07 30.8 1.0 0.00074 18.2 0.2 2.9 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 KIK68647.1 - 4.3e-07 30.2 1.9 0.16 12.4 0.1 5.5 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 KIK68647.1 - 6e-07 29.2 1.4 0.75 10.2 0.1 6.2 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 KIK68647.1 - 9.4e-06 25.8 2.4 0.054 13.7 0.1 4.0 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KIK68647.1 - 0.00021 20.6 1.9 0.024 13.8 0.3 3.1 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain OrfA PF17495.2 KIK68647.1 - 0.011 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Vpr-like OrfA HEAT_EZ PF13513.6 KIK68647.1 - 0.14 12.7 3.3 1.2e+02 3.3 0.0 5.6 5 2 2 7 7 7 0 HEAT-like repeat Cofilin_ADF PF00241.20 KIK68648.1 - 5.2e-40 136.0 0.6 5.8e-40 135.9 0.6 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DNA_pol3_beta_2 PF02767.16 KIK68648.1 - 0.06 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain RhoGEF PF00621.20 KIK68649.1 - 2.5e-39 135.4 0.5 4.7e-39 134.5 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KIK68649.1 - 1.6e-22 79.1 3.3 2.2e-11 43.4 0.1 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KIK68649.1 - 5.9e-20 70.6 0.6 1.5e-10 40.5 0.1 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.7 KIK68649.1 - 1.7e-18 66.5 0.0 4.2e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 KIK68649.1 - 3.6e-14 52.2 0.1 2.7e-07 30.2 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 KIK68649.1 - 5e-14 52.4 0.0 1.1e-11 44.8 0.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain WH2 PF02205.20 KIK68649.1 - 4.6e-08 32.6 0.1 1.3e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 WH2 motif PH PF00169.29 KIK68649.1 - 7.2e-05 23.3 0.0 0.00023 21.7 0.0 1.9 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.6 KIK68649.1 - 0.00062 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KIK68649.1 - 0.015 15.2 0.2 13 6.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KIK68649.1 - 0.015 14.8 0.0 0.91 9.2 0.0 2.6 2 0 0 2 2 2 0 EF hand TauD PF02668.16 KIK68653.1 - 3.9e-40 138.4 0.8 5.5e-40 137.9 0.8 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIK68653.1 - 2.4e-08 34.5 0.0 2.8e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 KIK68653.1 - 0.15 11.2 0.0 2 7.5 0.0 2.0 2 0 0 2 2 2 0 CsiD DUF5100 PF17029.5 KIK68653.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) Cnd3 PF12719.7 KIK68654.1 - 4.5e-59 200.1 9.5 7.8e-56 189.4 6.4 3.1 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KIK68654.1 - 0.00026 21.0 4.5 10 6.7 0.1 4.9 4 0 0 4 4 4 3 HEAT repeat DUF3384 PF11864.8 KIK68654.1 - 0.002 17.1 0.1 0.002 17.1 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) HEAT_2 PF13646.6 KIK68654.1 - 0.0082 16.5 2.5 0.065 13.6 0.2 3.1 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KIK68654.1 - 0.056 14.0 1.2 2.5 8.7 0.1 3.3 3 0 0 3 3 3 0 HEAT-like repeat Acetyltransf_6 PF13480.7 KIK68654.1 - 0.087 13.0 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CFEM PF05730.11 KIK68655.1 - 1.1e-07 31.8 5.0 1.3e-07 31.6 5.0 1.0 1 0 0 1 1 1 1 CFEM domain Sec23_trunk PF04811.15 KIK68656.1 - 1.5e-75 253.9 0.0 2.2e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KIK68656.1 - 1.5e-29 102.6 0.1 3.3e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KIK68656.1 - 1.5e-24 85.7 0.1 3.5e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KIK68656.1 - 1e-14 54.3 7.0 1.8e-14 53.5 7.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIK68656.1 - 1e-13 50.9 0.2 9.1e-13 47.9 0.3 2.4 2 1 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KIK68656.1 - 0.097 12.1 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cnd3 PF12719.7 KIK68659.1 - 8.8e-80 268.0 2.7 8.8e-80 268.0 2.7 2.3 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KIK68659.1 - 1.7e-08 34.7 0.6 1.3e-05 25.4 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KIK68659.1 - 4.5e-05 23.4 0.8 12 6.5 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KIK68659.1 - 0.035 14.2 0.1 0.38 10.8 0.0 2.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK68659.1 - 0.054 14.0 0.9 8.1 7.1 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat PCMT PF01135.19 KIK68660.1 - 1.4e-62 211.2 0.0 1.9e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KIK68660.1 - 0.0015 18.4 0.0 0.0036 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK68660.1 - 0.028 14.0 0.0 0.067 12.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KIK68660.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KIK68660.1 - 0.08 12.9 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain NDUF_B7 PF05676.13 KIK68661.1 - 5.4e-33 112.5 3.5 6.4e-33 112.3 3.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KIK68661.1 - 0.024 14.7 3.8 0.023 14.7 3.2 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Flavi_capsid PF01003.19 KIK68665.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C Phage-Gp8 PF09215.10 KIK68665.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 SMC_N PF02463.19 KIK68666.1 - 8.2e-32 110.4 0.5 9.9e-32 110.2 0.5 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK68666.1 - 3.4e-06 27.1 0.0 9.7e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system GAS PF13851.6 KIK68666.1 - 0.00014 21.3 28.0 0.034 13.5 3.5 3.2 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KIK68666.1 - 0.00028 19.7 10.0 0.048 12.3 4.6 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KIK68666.1 - 0.00076 19.7 0.0 0.003 17.7 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit WEMBL PF05701.11 KIK68666.1 - 0.00094 18.0 24.7 0.0051 15.6 4.3 2.2 2 0 0 2 2 2 2 Weak chloroplast movement under blue light YPEB PF14620.6 KIK68666.1 - 0.0011 18.3 12.3 0.014 14.8 1.1 2.1 2 0 0 2 2 2 2 YpeB sporulation MscS_porin PF12795.7 KIK68666.1 - 0.0013 18.4 17.8 0.016 14.7 0.9 2.4 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 KIK68666.1 - 0.0015 18.5 13.9 0.0059 16.6 6.0 2.6 2 0 0 2 2 2 1 Laminin Domain II DUF16 PF01519.16 KIK68666.1 - 0.0016 18.9 14.8 0.11 13.0 0.9 3.1 2 1 0 2 2 2 2 Protein of unknown function DUF16 RPW8 PF05659.11 KIK68666.1 - 0.0022 17.7 9.0 0.21 11.3 0.2 3.3 2 1 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 CHASE3 PF05227.13 KIK68666.1 - 0.0034 17.3 6.3 0.0034 17.3 6.3 2.4 2 0 0 2 2 2 1 CHASE3 domain LemA PF04011.12 KIK68666.1 - 0.0037 17.1 0.6 0.0037 17.1 0.6 2.4 2 0 0 2 2 2 1 LemA family OmpH PF03938.14 KIK68666.1 - 0.0049 17.2 25.6 0.13 12.6 9.3 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KIK68666.1 - 0.013 15.1 10.4 0.78 9.2 5.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit ING PF12998.7 KIK68666.1 - 0.014 16.0 2.8 0.014 16.0 2.8 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fmp27_WPPW PF10359.9 KIK68666.1 - 0.016 14.1 10.8 0.13 11.1 5.6 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 KIK68666.1 - 0.017 14.0 26.9 0.18 10.6 15.8 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF5082 PF16888.5 KIK68666.1 - 0.021 15.1 16.4 1.1 9.5 1.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 KIK68666.1 - 0.022 14.0 11.9 0.099 11.9 4.8 2.2 2 0 0 2 2 2 0 TMPIT-like protein TRAF_BIRC3_bd PF16673.5 KIK68666.1 - 0.025 14.4 7.7 0.43 10.4 0.3 3.3 3 0 0 3 3 2 0 TNF receptor-associated factor BIRC3 binding domain Atg14 PF10186.9 KIK68666.1 - 0.027 13.6 15.0 0.37 9.8 0.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 KIK68666.1 - 0.028 14.8 13.8 1.3 9.4 0.1 4.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KIK68666.1 - 0.035 14.2 13.7 0.46 10.5 3.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KIK68666.1 - 0.039 11.5 20.9 0.046 11.2 8.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 KIK68666.1 - 0.041 14.1 12.4 0.63 10.2 2.5 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HBM PF16591.5 KIK68666.1 - 0.051 13.0 13.2 0.051 13.0 3.6 2.3 2 0 0 2 2 2 0 Helical bimodular sensor domain Filament PF00038.21 KIK68666.1 - 0.053 13.1 26.7 0.54 9.8 13.1 2.8 2 1 0 2 2 2 0 Intermediate filament protein TolA_bind_tri PF16331.5 KIK68666.1 - 0.065 13.3 12.3 0.056 13.5 4.8 3.3 2 2 0 2 2 2 0 TolA binding protein trimerisation IFT57 PF10498.9 KIK68666.1 - 0.073 12.0 20.9 0.44 9.5 8.9 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 YkyA PF10368.9 KIK68666.1 - 0.077 12.7 28.3 0.32 10.6 13.3 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein EzrA PF06160.12 KIK68666.1 - 0.09 10.9 24.8 0.27 9.4 9.8 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA PTPA PF03095.15 KIK68666.1 - 0.18 11.2 2.0 8.9 5.7 0.1 2.3 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein T3SSipB PF16535.5 KIK68666.1 - 0.18 12.3 16.8 0.034 14.6 4.4 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB Mce4_CUP1 PF11887.8 KIK68666.1 - 0.23 10.9 1.4 1.3 8.4 0.2 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative FlgN PF05130.12 KIK68666.1 - 0.29 11.6 19.7 0.05 14.1 10.7 2.5 2 0 0 2 2 2 0 FlgN protein DUF724 PF05266.14 KIK68666.1 - 0.31 10.9 23.3 1 9.2 11.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.19 KIK68666.1 - 0.32 10.6 22.2 2 8.1 9.1 2.6 2 0 0 2 2 2 0 GrpE DUF745 PF05335.13 KIK68666.1 - 0.46 10.2 20.8 0.019 14.7 6.8 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF745) AATF-Che1 PF13339.6 KIK68666.1 - 0.46 11.2 13.8 1.4 9.6 5.6 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor TMF_TATA_bd PF12325.8 KIK68666.1 - 0.46 10.7 31.8 0.52 10.6 15.7 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding THOC7 PF05615.13 KIK68666.1 - 0.49 10.7 27.5 1.8 8.9 9.2 2.8 1 1 0 2 2 2 0 Tho complex subunit 7 HemX PF04375.14 KIK68666.1 - 0.51 9.6 18.2 1.1 8.5 2.2 2.6 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SKA1 PF07160.12 KIK68666.1 - 0.52 10.1 10.4 0.43 10.4 3.4 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Golgin_A5 PF09787.9 KIK68666.1 - 0.54 9.7 25.0 2 7.8 13.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Band_7 PF01145.25 KIK68666.1 - 0.59 10.1 4.5 2.7 8.0 3.8 2.3 1 1 0 1 1 1 0 SPFH domain / Band 7 family HAUS-augmin3 PF14932.6 KIK68666.1 - 0.65 9.5 21.1 1.6 8.3 12.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Muted PF14942.6 KIK68666.1 - 0.68 10.3 23.5 0.71 10.2 4.9 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4200 PF13863.6 KIK68666.1 - 0.71 10.3 32.8 0.04 14.3 14.5 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4200) Goodbye PF17109.5 KIK68666.1 - 0.78 10.2 8.5 2.7 8.4 1.1 2.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain FapA PF03961.13 KIK68666.1 - 0.88 8.1 19.0 1.2 7.6 9.1 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF948 PF06103.11 KIK68666.1 - 0.95 9.8 11.8 8 6.8 2.1 3.9 3 2 0 3 3 2 0 Bacterial protein of unknown function (DUF948) HeLo PF14479.6 KIK68666.1 - 1 9.2 8.5 1.2 9.0 1.7 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation Cytochrom_B562 PF07361.11 KIK68666.1 - 1.2 9.9 19.0 0.84 10.3 5.9 3.1 2 2 0 2 2 2 0 Cytochrome b562 Syntaxin_2 PF14523.6 KIK68666.1 - 1.3 9.5 10.5 0.43 11.0 0.8 2.8 2 1 0 2 2 2 0 Syntaxin-like protein zf-C4H2 PF10146.9 KIK68666.1 - 1.3 9.2 20.0 4.3 7.6 0.5 3.0 2 1 0 2 2 2 0 Zinc finger-containing protein DUF4407 PF14362.6 KIK68666.1 - 1.5 8.1 24.9 7e+02 -0.7 24.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CSN5_C PF18323.1 KIK68666.1 - 1.6 9.7 9.1 1.7 9.6 0.4 2.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain ADIP PF11559.8 KIK68666.1 - 1.8 8.6 24.8 1 9.5 4.0 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIK68666.1 - 1.8 8.6 32.4 0.043 13.8 5.3 3.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 KIK68666.1 - 1.8 8.5 28.1 0.28 11.2 7.3 4.1 2 2 1 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.9 KIK68666.1 - 1.9 8.8 23.0 0.84 10.0 4.9 4.4 3 2 2 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHR10 PF18595.1 KIK68666.1 - 2.2 8.3 32.7 0.71 9.9 5.2 3.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain FemAB PF02388.16 KIK68666.1 - 2.3 7.0 16.5 1.3 7.8 3.5 2.5 2 1 0 2 2 2 0 FemAB family NPV_P10 PF05531.12 KIK68666.1 - 2.6 8.6 8.2 10 6.7 0.3 3.7 2 2 1 3 3 2 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KIK68666.1 - 2.8 8.5 36.3 0.69 10.4 4.3 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region SlyX PF04102.12 KIK68666.1 - 2.9 8.6 18.0 15 6.3 0.2 4.2 2 2 1 3 3 3 0 SlyX IF-2B PF01008.17 KIK68666.1 - 3.2 6.9 8.8 1.2 8.3 1.3 2.2 2 0 0 2 2 2 0 Initiation factor 2 subunit family TPR_MLP1_2 PF07926.12 KIK68666.1 - 3.5 7.7 31.0 0.46 10.5 13.4 3.0 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KIK68666.1 - 4 7.5 15.7 5.7 7.0 0.9 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 KIK68666.1 - 4.1 7.5 24.8 1.9 8.6 14.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 KIK68666.1 - 4.2 7.9 15.7 9 6.8 1.3 2.9 2 1 0 2 2 2 0 Snapin/Pallidin CorA PF01544.18 KIK68666.1 - 4.5 6.5 14.0 0.77 9.0 4.6 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PCRF PF03462.18 KIK68666.1 - 4.5 7.1 22.1 7.2 6.4 9.6 2.3 2 0 0 2 2 2 0 PCRF domain Syntaxin-6_N PF09177.11 KIK68666.1 - 5 7.7 12.7 3.7 8.2 6.6 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF3037 PF11236.8 KIK68666.1 - 6.3 7.3 8.6 21 5.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Tweety PF04906.13 KIK68666.1 - 6.6 5.3 5.0 1.9 7.1 1.1 1.8 2 0 0 2 2 2 0 Tweety MRP-S26 PF14943.6 KIK68666.1 - 6.9 6.5 22.3 1.1 9.1 8.5 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Tho2 PF11262.8 KIK68666.1 - 8.7 5.4 12.7 7.7 5.6 2.2 2.5 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF2730 PF10805.8 KIK68666.1 - 9.4 6.4 10.1 9.1 6.4 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) SMC_N PF02463.19 KIK68668.1 - 6.3e-11 42.1 0.1 7.6e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Chor_lyase PF04345.13 KIK68668.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Chorismate lyase MaoC_dehydratas PF01575.19 KIK68669.1 - 4.2e-29 100.6 0.0 9.5e-29 99.5 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIK68669.1 - 3.7e-05 23.9 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KIK68670.1 - 3.2e-29 101.0 0.0 6.9e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIK68670.1 - 5.3e-09 36.3 0.0 2.6e-05 24.4 0.0 2.6 2 2 0 2 2 2 2 N-terminal half of MaoC dehydratase Rad52_Rad22 PF04098.15 KIK68671.1 - 1.5e-56 190.6 0.0 1.7e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF1091 PF06477.13 KIK68671.1 - 0.067 13.7 0.1 18 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) FAD_binding_3 PF01494.19 KIK68672.1 - 4.5e-21 75.5 0.1 9.9e-21 74.4 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK68672.1 - 3.2e-05 24.1 1.1 0.0001 22.4 1.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK68672.1 - 4e-05 23.0 0.4 0.00038 19.8 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK68672.1 - 0.00014 21.6 0.4 0.00023 20.8 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIK68672.1 - 0.00064 19.1 1.5 0.013 14.8 1.2 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIK68672.1 - 0.0033 16.5 3.7 0.024 13.7 0.9 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KIK68672.1 - 0.0035 16.3 2.0 1.5 7.6 2.3 2.3 1 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KIK68672.1 - 0.0069 15.5 3.4 0.013 14.7 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK68672.1 - 0.018 13.7 0.2 0.036 12.8 0.2 1.5 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KIK68672.1 - 0.11 13.0 0.2 0.38 11.4 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SRF-TF PF00319.18 KIK68673.1 - 1.5e-12 46.7 0.0 2.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ornatin PF02088.15 KIK68675.1 - 0.052 13.3 0.5 0.093 12.5 0.5 1.4 1 0 0 1 1 1 0 Ornatin Peptidase_S9 PF00326.21 KIK68676.1 - 1.3e-34 119.5 0.0 1.9e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KIK68676.1 - 5e-10 39.0 0.1 0.042 13.8 0.0 4.2 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 KIK68676.1 - 4.9e-05 23.1 0.2 0.0016 18.1 0.2 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIK68676.1 - 9.1e-05 22.4 0.1 0.00016 21.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68676.1 - 0.00012 22.8 0.5 0.00033 21.3 0.5 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KIK68676.1 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KIK68676.1 - 0.004 16.7 0.2 0.0088 15.6 0.2 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KIK68676.1 - 0.0053 16.0 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIP PF03583.14 KIK68676.1 - 0.025 13.9 0.2 0.22 10.8 0.4 2.3 2 1 1 3 3 3 0 Secretory lipase Cytochrom_D1 PF02239.16 KIK68676.1 - 0.15 10.6 0.0 1.5 7.3 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain Glyco_hydro_71 PF03659.14 KIK68677.1 - 8.1e-96 321.1 13.5 8.1e-96 321.1 13.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 WSC PF01822.19 KIK68677.1 - 1.3e-35 121.4 60.7 6e-17 61.6 15.0 4.4 5 0 0 5 5 5 3 WSC domain Peptidase_C14 PF00656.22 KIK68678.1 - 1.2e-29 104.0 0.0 2.2e-29 103.2 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Fungal_trans PF04082.18 KIK68679.1 - 1.9e-24 86.1 0.0 3.1e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.26 KIK68681.1 - 2.3e-08 33.9 0.0 7.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Macoilin PF09726.9 KIK68681.1 - 0.0018 16.9 2.3 0.0018 16.9 2.3 2.9 3 1 0 3 3 3 1 Macoilin family Spc42p PF11544.8 KIK68681.1 - 0.16 11.9 0.8 0.52 10.3 0.8 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p SlyX PF04102.12 KIK68681.1 - 0.4 11.3 3.7 5.4 7.7 0.0 2.5 2 0 0 2 2 2 0 SlyX PKcGMP_CC PF16808.5 KIK68681.1 - 4.2 7.3 6.6 0.6 10.0 2.6 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KIK68681.1 - 6.7 7.1 7.4 0.79 10.1 0.6 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Glyco_hydro_62 PF03664.13 KIK68682.1 - 4.5e-63 213.1 12.1 5.8e-63 212.8 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 SIS PF01380.22 KIK68684.1 - 6.6e-63 210.4 0.1 1.4e-33 115.5 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KIK68684.1 - 3.7e-16 59.5 0.0 9.8e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIK68684.1 - 1.3e-11 44.5 0.0 3.7e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIK68684.1 - 4.3e-05 22.6 0.0 7.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KIK68684.1 - 0.033 12.9 0.0 0.072 11.8 0.0 1.5 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Arfaptin PF06456.13 KIK68685.1 - 0.0033 17.0 0.4 0.0093 15.6 0.1 1.8 1 1 1 2 2 2 1 Arfaptin-like domain DUF1192 PF06698.11 KIK68685.1 - 4 7.6 5.7 2.5 8.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) TENA_THI-4 PF03070.16 KIK68686.1 - 2.8e-05 24.0 0.0 0.00019 21.3 0.0 1.9 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DUF4632 PF15451.6 KIK68686.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Mitoc_mL59 PF18126.1 KIK68687.1 - 5.3e-42 143.2 4.1 8e-42 142.6 4.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 NmrA PF05368.13 KIK68688.1 - 4.5e-13 49.3 0.0 1.5e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK68688.1 - 2.3e-07 30.9 0.0 4.7e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIK68688.1 - 4.7e-07 29.5 0.1 9.4e-06 25.3 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK68688.1 - 7.4e-05 22.3 0.2 0.0049 16.3 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIK68688.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KIK68688.1 - 0.0044 17.3 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIK68688.1 - 0.015 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 KR domain RRM_1 PF00076.22 KIK68690.1 - 1.9e-37 126.9 0.0 1.7e-19 69.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KIK68690.1 - 5.4e-11 42.5 0.0 3e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 KIK68690.1 - 0.03 14.4 0.2 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 CPSase_C PF18302.1 KIK68690.1 - 0.21 12.1 0.2 0.95 10.1 0.2 2.2 1 0 0 1 1 1 0 Carbamoyl phosphate synthetase C-terminal domain ADH_zinc_N PF00107.26 KIK68691.1 - 3.2e-08 33.6 0.0 6.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK68691.1 - 4.2e-08 33.0 0.0 1.6e-07 31.2 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK68691.1 - 0.00046 21.3 0.0 0.00083 20.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK68691.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase FoP_duplication PF13865.6 KIK68692.1 - 1.6e-10 41.3 2.1 1.6e-10 41.3 2.1 1.9 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KIK68692.1 - 3.3e-10 39.6 0.0 6.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Potassium_chann PF11404.8 KIK68692.1 - 0.13 12.1 1.1 0.27 11.1 1.1 1.5 1 0 0 1 1 1 0 Potassium voltage-gated channel WD40 PF00400.32 KIK68693.1 - 1.5e-32 111.1 28.8 2e-06 28.4 0.7 11.4 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68693.1 - 2.9e-21 75.6 0.4 4.5e-09 36.5 0.0 6.3 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK68693.1 - 7.2e-07 29.3 0.4 0.037 13.9 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK68693.1 - 1.5e-05 24.2 0.1 0.25 10.2 0.0 3.7 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK68693.1 - 0.00036 20.0 0.3 0.45 9.8 0.0 3.2 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 KIK68693.1 - 0.0021 17.4 0.0 0.2 10.9 0.0 3.6 5 0 0 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.12 KIK68693.1 - 0.0034 15.5 0.0 1 7.3 0.0 3.0 3 0 0 3 3 3 1 IKI3 family CPSF_A PF03178.15 KIK68693.1 - 0.0038 16.6 0.0 0.72 9.1 0.0 2.9 3 0 0 3 3 3 1 CPSF A subunit region PD40 PF07676.12 KIK68693.1 - 0.061 13.3 0.1 20 5.3 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK68693.1 - 0.092 12.1 0.0 7 5.9 0.0 3.3 2 1 1 3 3 3 0 WD40-like domain MFS_1 PF07690.16 KIK68694.1 - 9.4e-31 107.0 28.8 9.4e-31 107.0 28.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Mad3_BUB1_I PF08311.12 KIK68696.1 - 2.5e-35 121.1 0.1 4.3e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KIK68696.1 - 0.21 11.7 0.1 0.34 11.0 0.1 1.2 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Acetyltransf_1 PF00583.25 KIK68698.1 - 1.3e-12 48.0 0.0 1.8e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK68698.1 - 3.2e-10 40.3 0.1 7.4e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK68698.1 - 6.4e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK68698.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KIK68698.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KIK68698.1 - 0.0048 16.9 0.1 0.0087 16.0 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KIK68698.1 - 0.048 13.1 0.1 0.25 10.8 0.0 1.8 1 1 0 2 2 2 0 Putative acetyl-transferase DUF4131 PF13567.6 KIK68698.1 - 0.058 13.0 0.1 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Acetyltransf_9 PF13527.7 KIK68698.1 - 0.059 13.4 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KIK68698.1 - 0.12 13.1 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4083 PF13314.6 KIK68698.1 - 0.36 10.8 1.0 1.1 9.2 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF4588 PF15251.6 KIK68699.1 - 4.7e-05 23.3 1.0 6.4e-05 22.9 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF3136 PF11334.8 KIK68699.1 - 0.043 13.6 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Oxidored_FMN PF00724.20 KIK68700.1 - 4.1e-93 312.4 0.0 4.7e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIK68700.1 - 0.094 12.1 0.0 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Dak1 PF02733.17 KIK68701.1 - 1.2e-102 343.0 0.0 1.6e-102 342.6 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KIK68701.1 - 2.1e-35 122.2 2.1 2.1e-35 122.2 2.1 1.7 2 0 0 2 2 2 1 DAK2 domain Glyco_hydro_3_C PF01915.22 KIK68702.1 - 1.6e-44 152.3 0.0 2.4e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK68702.1 - 2.5e-27 96.1 0.0 4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK68702.1 - 1.1e-10 41.4 0.0 2.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DJ-1_PfpI PF01965.24 KIK68703.1 - 1.7e-38 132.0 0.0 1.9e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK68703.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 ThiJ/PfpI family-like GATase_3 PF07685.14 KIK68703.1 - 0.051 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Abhydrolase_1 PF00561.20 KIK68704.1 - 7.6e-16 58.5 0.0 1.9e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68704.1 - 4.5e-15 56.8 0.0 6.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK68704.1 - 1.8e-10 40.5 0.0 2.6e-10 40.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIK68704.1 - 1.5e-09 38.3 0.0 2.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KIK68704.1 - 3e-06 27.1 0.0 1e-05 25.4 0.0 1.9 2 1 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KIK68704.1 - 5.6e-06 26.0 0.0 9.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 KIK68704.1 - 0.00075 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 KIK68704.1 - 0.011 15.4 0.1 0.027 14.1 0.1 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KIK68704.1 - 0.012 15.4 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KIK68704.1 - 0.015 15.2 0.2 0.037 13.9 0.1 1.6 1 1 1 2 2 2 0 Lipase (class 3) Chlorophyllase PF07224.11 KIK68704.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF900 PF05990.12 KIK68704.1 - 0.051 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DFP PF04127.15 KIK68705.1 - 3.1e-20 72.8 0.0 9.4e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 KIK68705.1 - 0.12 12.7 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KIK68706.1 - 4.5e-67 226.2 0.0 2.1e-64 217.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68706.1 - 2.7e-34 118.6 0.0 1.8e-30 106.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK68706.1 - 1.1e-05 24.4 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK68706.1 - 0.00021 20.7 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK68706.1 - 0.003 16.9 0.2 0.0069 15.8 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KIK68706.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Oxidored_FMN PF00724.20 KIK68707.1 - 3.9e-99 332.1 0.0 4.5e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_3_C PF01915.22 KIK68708.1 - 1.7e-42 145.7 0.0 2.6e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK68708.1 - 8.4e-32 110.8 0.0 1.4e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK68708.1 - 4e-09 36.4 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Retrotran_gag_2 PF14223.6 KIK68710.1 - 2.1e-16 59.8 1.0 2.3e-16 59.7 1.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sec2p PF06428.11 KIK68711.1 - 3e-11 43.2 13.2 3e-11 43.2 13.2 2.2 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p Mononeg_mRNAcap PF14318.6 KIK68711.1 - 0.038 13.2 0.1 0.086 12.1 0.1 1.5 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Herpes_UL6 PF01763.16 KIK68711.1 - 0.24 9.9 4.5 0.26 9.8 3.3 1.7 1 1 0 1 1 1 0 Herpesvirus UL6 like Peroxidase_2 PF01328.17 KIK68712.1 - 1.6e-18 67.9 0.0 2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 KIK68713.1 - 9.8e-19 68.6 0.1 1.4e-18 68.1 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 KIK68714.1 - 3e-12 47.5 1.1 2.5e-10 41.2 0.1 2.1 1 1 1 2 2 2 2 Peroxidase, family 2 Peptidase_C14 PF00656.22 KIK68715.1 - 6e-22 78.8 0.0 9.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Amino_oxidase PF01593.24 KIK68716.1 - 1e-41 143.7 0.0 3.2e-40 138.8 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK68716.1 - 1.4e-10 41.3 0.0 1.3e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK68716.1 - 0.016 14.5 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KIK68716.1 - 0.069 13.7 0.1 0.7 10.5 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK68716.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lipase_3 PF01764.25 KIK68718.1 - 3.1e-17 62.7 0.0 8.1e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK68718.1 - 0.0006 20.5 0.2 0.00088 19.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK68718.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIK68718.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0730 PF15827.5 KIK68718.1 - 0.037 13.8 2.3 0.09 12.5 2.3 1.6 1 0 0 1 1 1 0 UPF0730 unknown protein family Abhydrolase_1 PF00561.20 KIK68719.1 - 1e-20 74.5 0.0 1.4e-17 64.2 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK68719.1 - 9.4e-16 59.1 8.3 2.5e-14 54.4 8.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK68719.1 - 6.2e-11 42.0 0.0 6.3e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 KIK68719.1 - 0.0017 18.7 0.2 0.0037 17.6 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Esterase PF00756.20 KIK68719.1 - 0.0068 16.1 0.2 0.013 15.2 0.2 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KIK68719.1 - 0.094 11.4 0.0 0.28 9.8 0.0 1.7 2 0 0 2 2 2 0 Ndr family F-box-like PF12937.7 KIK68720.1 - 6.8e-05 22.7 0.1 0.00019 21.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK68720.1 - 0.00025 20.9 3.9 0.00034 20.4 0.4 2.7 2 1 0 2 2 2 1 F-box domain Formyl_trans_N PF00551.19 KIK68722.1 - 1.5e-18 67.2 0.0 2.5e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KIK68722.1 - 1.9e-07 31.2 0.0 3.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Glyco_hydro_79C PF16862.5 KIK68723.1 - 1.6e-20 73.9 0.2 4.6e-20 72.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_92 PF07971.12 KIK68724.1 - 1.9e-121 406.2 1.3 2.4e-121 405.9 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK68724.1 - 2e-41 142.5 3.7 4.2e-41 141.4 3.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Myb_DNA-binding PF00249.31 KIK68725.1 - 4.2e-41 138.9 4.1 4.9e-14 52.2 0.3 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK68725.1 - 5.2e-28 97.1 0.2 5e-16 58.7 0.2 2.9 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 KIK68725.1 - 2.7e-06 27.4 0.3 0.0025 17.8 0.1 3.1 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 KIK68725.1 - 9.8e-06 25.4 0.1 0.19 11.6 0.0 2.7 3 0 0 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KIK68725.1 - 3.4e-05 23.9 0.0 2.5 8.4 0.0 3.6 3 1 0 3 3 3 2 Rap1 Myb domain SLIDE PF09111.10 KIK68725.1 - 4.6e-05 23.4 0.0 0.7 9.9 0.0 3.0 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 KIK68725.1 - 0.0063 16.7 0.8 0.9 9.8 0.0 2.7 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 KIK68725.1 - 0.077 13.3 1.6 4.7 7.6 0.4 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_III_AB PF09548.10 KIK68725.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HAT PF02184.16 KIK68727.1 - 1e-25 89.4 55.9 3.1e-10 39.8 3.3 14.0 14 1 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KIK68727.1 - 2.8e-23 80.6 24.2 0.0054 17.5 0.1 11.4 5 2 8 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68727.1 - 2.3e-12 47.2 0.7 0.21 12.1 0.1 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68727.1 - 7.5e-11 41.3 4.0 0.74 10.1 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK68727.1 - 1.1e-07 31.8 1.7 0.0035 17.6 0.0 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK68727.1 - 9.3e-07 28.6 1.3 13 6.3 0.0 7.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 KIK68727.1 - 2.2e-05 23.8 21.0 0.24 10.6 0.1 5.9 2 2 3 5 5 5 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIK68727.1 - 0.00028 20.9 21.8 0.13 12.2 0.2 7.3 5 2 1 6 6 6 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 KIK68727.1 - 0.00034 21.2 12.7 1 10.0 0.1 7.0 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK68727.1 - 0.00058 19.6 0.4 26 4.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK68727.1 - 0.007 16.0 0.8 5 6.9 0.0 4.1 5 0 0 5 5 5 1 TPR repeat TPR_6 PF13174.6 KIK68727.1 - 0.018 15.6 15.5 36 5.3 0.0 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68727.1 - 0.037 14.0 11.9 8.9 6.6 0.0 7.4 10 0 0 10 10 9 0 Tetratricopeptide repeat SNAP PF14938.6 KIK68727.1 - 0.043 13.2 2.4 0.89 8.9 0.6 3.5 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 KIK68727.1 - 1.4 9.1 11.9 7.9 6.7 0.3 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TFIIE-A_C PF11521.8 KIK68727.1 - 1.6 9.1 6.9 0.15 12.3 0.9 2.4 2 0 0 2 2 1 0 C-terminal general transcription factor TFIIE alpha U3_assoc_6 PF08640.11 KIK68727.1 - 2.9 8.0 19.1 0.051 13.6 1.0 5.4 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 CsbD PF05532.12 KIK68728.1 - 0.017 15.0 3.7 0.044 13.7 3.7 1.7 1 0 0 1 1 1 0 CsbD-like TPR_10 PF13374.6 KIK68728.1 - 0.17 11.8 2.3 0.39 10.7 2.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_92 PF07971.12 KIK68729.1 - 2.6e-120 402.5 2.7 3.2e-120 402.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK68729.1 - 8.4e-42 143.7 5.2 1.4e-41 142.9 5.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Asp PF00026.23 KIK68730.1 - 3.9e-12 46.2 0.2 6.3e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Pheromone PF08015.11 KIK68731.1 - 0.045 14.8 5.7 0.072 14.1 0.2 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Pkinase_Tyr PF07714.17 KIK68732.1 - 2.3e-16 59.8 0.0 2.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK68732.1 - 3.7e-11 42.9 0.0 4.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68733.1 - 7e-20 71.4 0.0 7.9e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK68733.1 - 7.2e-16 58.3 0.0 8.5e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Cnd3 PF12719.7 KIK68734.1 - 0.0025 17.1 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain VWA PF00092.28 KIK68735.1 - 2.9e-08 34.1 0.0 5.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK68735.1 - 2.9e-08 34.3 0.0 2e-07 31.6 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain Dyp_perox PF04261.12 KIK68735.1 - 2.9e-07 29.8 0.3 6.2e-05 22.1 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family Integrin_beta PF00362.18 KIK68735.1 - 8.7e-05 22.3 0.0 0.00064 19.5 0.0 2.0 1 1 0 1 1 1 1 Integrin beta chain VWA domain Amino_oxidase PF01593.24 KIK68736.1 - 7.5e-47 160.6 0.0 6.6e-46 157.5 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK68736.1 - 7.8e-11 42.0 0.0 3.2e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK68736.1 - 0.0087 16.6 0.0 0.72 10.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK68736.1 - 0.016 14.5 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain BAG PF02179.16 KIK68736.1 - 0.08 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 BAG domain HI0933_like PF03486.14 KIK68736.1 - 0.13 10.9 0.0 0.88 8.2 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein PCuAC PF04314.13 KIK68736.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Copper chaperone PCu(A)C Pyr_redox_2 PF07992.14 KIK68736.1 - 0.16 11.2 0.0 0.42 9.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK68736.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C14 PF00656.22 KIK68737.1 - 1.2e-26 94.2 0.0 1.9e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain VWA PF00092.28 KIK68737.1 - 0.00013 22.3 0.0 0.00038 20.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK68737.1 - 0.00014 22.5 0.0 0.00082 20.0 0.0 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain RicinB_lectin_2 PF14200.6 KIK68737.1 - 0.021 15.5 1.7 0.095 13.4 0.7 2.4 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Peptidase_C14 PF00656.22 KIK68739.1 - 2.9e-22 79.9 0.0 4.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 KIK68739.1 - 0.0014 18.1 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 CHAT domain CHAT PF12770.7 KIK68740.1 - 3.9e-32 111.8 0.0 5.9e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KIK68740.1 - 0.0014 18.7 0.2 0.88 9.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK68740.1 - 0.028 14.2 0.3 0.28 11.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68740.1 - 0.32 11.5 6.1 8.4 7.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68740.1 - 0.61 10.2 2.1 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68740.1 - 0.65 10.3 4.6 2.7 8.3 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK68740.1 - 1.8 9.3 0.0 1.8 9.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK68740.1 - 3.4 8.0 8.2 31 4.9 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Cnd3 PF12719.7 KIK68741.1 - 4.3e-77 259.2 1.3 1.2e-76 257.8 0.5 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KIK68741.1 - 4.7e-08 33.3 6.5 0.0052 17.1 0.1 5.9 5 2 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KIK68741.1 - 2.2e-07 30.6 8.4 0.94 9.9 0.0 6.9 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 KIK68741.1 - 0.001 17.8 1.1 0.51 8.8 0.0 2.8 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 KIK68741.1 - 3.6 8.2 9.0 17 6.0 0.0 5.6 7 0 0 7 7 7 0 HEAT-like repeat Pox_Ag35 PF03286.14 KIK68741.1 - 8.8 6.1 18.1 8.7 6.1 7.5 3.2 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DnaJ PF00226.31 KIK68742.1 - 4.3e-19 68.4 2.0 1.4e-18 66.7 0.1 2.5 3 0 0 3 3 2 1 DnaJ domain TPR_1 PF00515.28 KIK68742.1 - 2.6e-11 42.8 1.1 0.00051 19.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68742.1 - 9.3e-10 37.9 7.9 0.0045 17.0 0.0 6.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK68742.1 - 2.1e-09 37.9 5.4 1.8e-07 31.7 0.3 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68742.1 - 5.5e-09 36.4 6.0 1.3e-05 25.6 0.6 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK68742.1 - 1.6e-08 34.1 2.2 7.3e-07 28.8 1.4 3.6 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 KIK68742.1 - 5.2e-07 29.6 0.3 0.011 16.0 0.3 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK68742.1 - 1.4e-06 28.0 3.2 0.039 14.2 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK68742.1 - 1.5e-06 28.4 6.7 0.032 14.5 0.3 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK68742.1 - 2.6e-06 27.8 11.1 0.11 13.4 0.1 6.3 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK68742.1 - 0.00053 20.5 6.6 7.9 7.4 0.1 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK68742.1 - 0.0012 18.9 0.4 0.22 11.7 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68742.1 - 0.003 17.5 2.5 9.4 6.5 0.1 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat PknG_TPR PF16918.5 KIK68742.1 - 0.0032 16.3 0.0 1.2 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 KIK68742.1 - 0.013 16.0 0.2 31 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KIK68742.1 - 0.025 15.0 0.5 0.46 10.9 0.0 2.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KIK68742.1 - 0.038 14.2 4.4 0.94 9.7 0.9 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PBAN PF05874.11 KIK68742.1 - 0.064 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Serine_rich PF08824.10 KIK68742.1 - 0.24 11.4 4.4 13 5.7 0.8 3.4 2 1 1 3 3 3 0 Serine rich protein interaction domain TPR_20 PF14561.6 KIK68742.1 - 0.47 10.8 5.7 0.69 10.3 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK68742.1 - 2.2 8.3 7.3 11 6.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KIK68742.1 - 4.3 7.5 6.3 1.6 8.9 0.0 3.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Epimerase PF01370.21 KIK68744.1 - 6.8e-18 65.0 0.2 3.1e-17 62.8 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK68744.1 - 6.4e-13 48.3 0.0 8.6e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK68744.1 - 9e-11 41.4 0.0 5.5e-06 25.7 0.0 2.7 3 0 0 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 KIK68744.1 - 1.7e-08 34.5 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK68744.1 - 4.1e-05 23.2 1.7 0.00014 21.5 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KIK68744.1 - 0.022 14.2 0.1 0.15 11.5 0.1 2.2 2 1 0 2 2 2 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KIK68744.1 - 0.055 12.9 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK68744.1 - 0.097 11.8 0.1 0.21 10.7 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KIK68744.1 - 0.15 12.1 0.1 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Amidohydro_1 PF01979.20 KIK68747.1 - 9.2e-19 67.9 0.0 2.5e-16 59.9 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIK68747.1 - 1.1e-08 35.0 0.5 6.9e-05 22.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family NMD3 PF04981.13 KIK68748.1 - 1.3e-80 270.4 0.9 1.7e-80 270.0 0.9 1.1 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 KIK68748.1 - 0.009 15.9 1.4 0.17 11.8 0.7 2.7 3 0 0 3 3 3 1 NinF protein DZR PF12773.7 KIK68748.1 - 0.035 14.1 6.3 0.69 10.0 1.0 2.7 1 1 0 2 2 2 0 Double zinc ribbon HEPN_Apea PF18739.1 KIK68748.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Apea-like HEPN SWIRM-assoc_2 PF16496.5 KIK68748.1 - 0.12 11.2 1.3 0.18 10.7 1.3 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF35_N PF12172.8 KIK68748.1 - 0.19 11.7 8.8 1.1 9.2 0.5 3.4 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rpr2 PF04032.16 KIK68748.1 - 1.4 9.2 3.7 25 5.2 2.2 2.9 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TT_ORF2 PF02957.15 KIK68748.1 - 7.7 7.5 8.3 24 5.9 0.2 2.5 1 1 1 2 2 2 0 TT viral ORF2 DUF4523 PF15023.6 KIK68749.1 - 0.0035 17.2 0.0 1.5 8.6 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF4523) ERAP1_C PF11838.8 KIK68750.1 - 2.5e-67 227.7 0.0 4.7e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KIK68750.1 - 1.9e-61 207.4 0.9 3.2e-61 206.7 0.9 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIK68750.1 - 5.5e-40 137.5 0.0 1.3e-39 136.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF1773 PF08593.10 KIK68751.1 - 0.0019 19.2 0.6 0.011 16.7 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function Claudin_2 PF13903.6 KIK68753.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction ERAP1_C PF11838.8 KIK68755.1 - 4e-66 223.7 0.1 4.7e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF2004 PF09406.10 KIK68755.1 - 0.057 13.7 0.2 0.46 10.8 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2004) ERAP1_C PF11838.8 KIK68757.1 - 5.7e-45 154.2 0.6 6.4e-44 150.8 0.6 2.1 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KIK68757.1 - 5e-43 147.2 0.3 4.2e-42 144.2 0.2 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIK68757.1 - 1.1e-36 126.7 0.0 2.7e-36 125.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain UPF0004 PF00919.20 KIK68757.1 - 0.091 12.8 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 E1-E2_ATPase PF00122.20 KIK68758.1 - 1.3e-48 164.9 0.1 1.3e-48 164.9 0.1 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KIK68758.1 - 1.4e-18 67.9 3.2 4.5e-18 66.3 3.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK68758.1 - 5.7e-13 48.3 0.1 1.5e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK68758.1 - 0.00026 20.8 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK68758.1 - 0.0081 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pkinase PF00069.25 KIK68759.1 - 2.3e-16 60.0 0.0 2.5e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68759.1 - 7.9e-07 28.6 0.0 8.4e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK68759.1 - 0.058 13.3 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_transf_24 PF18404.1 KIK68760.1 - 2.5e-142 473.1 1.7 3.7e-142 472.5 1.7 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KIK68760.1 - 3e-68 230.5 0.1 8.5e-62 209.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KIK68760.1 - 8.2e-55 185.6 0.0 5.6e-54 182.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KIK68760.1 - 4.3e-40 136.2 0.0 8.6e-40 135.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KIK68760.1 - 2.2e-39 134.5 1.3 3.7e-38 130.5 0.6 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KIK68760.1 - 2.2e-37 129.1 0.7 5.4e-37 127.8 0.7 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KIK68760.1 - 3.3e-05 23.6 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Asp PF00026.23 KIK68762.1 - 1.1e-32 113.8 3.1 1.6e-32 113.2 3.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK68762.1 - 0.00024 21.4 3.0 0.021 15.1 0.0 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KIK68762.1 - 0.0058 17.2 0.0 6.2 7.4 0.0 3.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KIK68762.1 - 0.033 14.0 0.0 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIK68762.1 - 0.049 14.3 0.9 16 6.3 0.1 3.4 3 1 0 3 3 3 0 Aspartyl protease Peptidase_M17 PF00883.21 KIK68763.1 - 1.7e-116 388.9 0.1 2.5e-116 388.3 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIK68763.1 - 0.0011 18.9 0.1 0.0032 17.3 0.1 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain zf-CCHC PF00098.23 KIK68764.1 - 0.015 15.4 1.6 0.028 14.5 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_2 PF14608.6 KIK68764.1 - 0.056 13.9 2.9 0.11 13.0 2.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCHC_5 PF14787.6 KIK68764.1 - 3.4 7.4 7.4 0.53 10.0 3.3 1.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Peptidase_M17 PF00883.21 KIK68766.1 - 6.8e-119 396.7 0.1 9.7e-119 396.2 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIK68766.1 - 0.001 18.9 0.0 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Asp PF00026.23 KIK68767.1 - 1.4e-44 152.9 10.3 1.9e-44 152.4 10.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK68767.1 - 3.9e-05 24.0 0.5 0.0061 16.8 0.0 3.4 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK68767.1 - 0.0059 16.4 0.4 2.1 8.1 0.0 2.6 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Zn_clus PF00172.18 KIK68770.1 - 7.5e-07 29.2 7.0 1.2e-06 28.5 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_6 PF13516.6 KIK68771.1 - 3.2e-05 23.6 1.9 0.021 14.9 0.1 3.5 2 1 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KIK68771.1 - 0.00022 21.5 0.0 0.37 11.3 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) SAP PF02037.27 KIK68771.1 - 0.14 11.9 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 SAP domain LRR_8 PF13855.6 KIK68771.1 - 0.31 10.8 1.7 25 4.7 0.2 2.8 2 1 0 2 2 2 0 Leucine rich repeat Glyco_hyd_65N_2 PF14498.6 KIK68773.1 - 3.6e-52 177.6 0.7 5.2e-52 177.0 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain RNase_H2_suC PF08615.11 KIK68774.1 - 5.6e-24 84.9 0.0 7.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3533 PF12051.8 KIK68776.1 - 7e-97 324.7 19.9 8.1e-97 324.5 19.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Bunya_G2 PF03563.13 KIK68776.1 - 0.026 13.8 1.4 0.045 13.0 1.4 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 GMC_oxred_N PF00732.19 KIK68776.1 - 0.058 12.8 0.1 0.082 12.3 0.1 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Amino_oxidase PF01593.24 KIK68777.1 - 4.8e-31 108.5 0.0 6e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK68777.1 - 5e-10 39.5 0.0 5e-10 39.5 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK68777.1 - 1.7e-06 27.9 0.0 1.7e-06 27.9 0.0 1.8 2 0 0 2 2 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK68777.1 - 0.0002 20.7 0.0 0.00047 19.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK68777.1 - 0.00065 19.0 0.2 0.0085 15.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK68777.1 - 0.0011 19.4 2.4 0.12 12.9 0.0 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK68777.1 - 0.002 18.2 2.2 0.02 14.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KIK68777.1 - 0.0037 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK68777.1 - 0.008 14.9 0.0 0.43 9.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein MCRA PF06100.11 KIK68777.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 KIK68777.1 - 0.016 14.3 0.1 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KIK68777.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KIK68777.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KIK68777.1 - 0.039 13.2 0.1 4.2 6.6 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KIK68777.1 - 0.068 12.3 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 KIK68777.1 - 0.11 11.0 0.0 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) SPC25 PF06703.11 KIK68778.1 - 3.6e-52 176.4 0.0 4.2e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4748 PF15932.5 KIK68778.1 - 0.096 12.5 0.5 0.24 11.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) GMC_oxred_N PF00732.19 KIK68780.1 - 1.1e-58 199.0 0.0 1.5e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK68780.1 - 3.9e-29 102.0 0.0 7.1e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK68780.1 - 7e-05 22.0 0.2 0.00011 21.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK68780.1 - 0.00013 21.2 0.3 0.0063 15.6 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain DUF5539 PF17693.1 KIK68780.1 - 0.027 14.1 0.3 0.056 13.1 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5539) HHH_5 PF14520.6 KIK68780.1 - 0.05 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 KIK68780.1 - 0.18 11.8 0.1 0.82 9.7 0.1 2.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif UQ_con PF00179.26 KIK68781.1 - 7e-50 168.3 0.0 8.2e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK68781.1 - 0.00068 19.3 0.0 0.00089 19.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RGCC PF15151.6 KIK68781.1 - 0.087 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Response gene to complement 32 protein family Glyco_hydro_35 PF01301.19 KIK68783.1 - 5.3e-76 256.2 0.2 7.9e-76 255.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIK68783.1 - 2.8e-57 192.2 0.9 4.8e-32 110.9 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIK68783.1 - 1.3e-29 103.3 0.1 2.1e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIK68783.1 - 4.4e-16 58.2 0.1 1.5e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.14 KIK68783.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidase PF01425.21 KIK68785.1 - 4.5e-101 339.0 0.0 5.3e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Pkinase PF00069.25 KIK68787.1 - 2e-68 230.6 0.0 3e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68787.1 - 9.5e-42 143.1 0.0 1.6e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KIK68787.1 - 3.1e-34 117.0 3.5 1.1e-17 64.0 0.2 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KIK68787.1 - 3.9e-07 29.7 0.0 2.3e-06 27.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KIK68787.1 - 0.00051 19.1 0.1 0.0022 17.0 0.0 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KIK68787.1 - 0.034 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prok_Ub PF14454.6 KIK68789.1 - 0.034 13.8 0.0 2.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Prokaryotic Ubiquitin FMO-like PF00743.19 KIK68790.1 - 3.7e-11 42.1 0.0 5.8e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK68790.1 - 6.4e-08 32.2 0.0 8.4e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK68790.1 - 2.6e-07 30.7 0.0 6.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIK68790.1 - 9.3e-07 28.3 0.0 3.4e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KIK68790.1 - 1e-06 28.3 0.0 4.6e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK68790.1 - 6.5e-06 26.0 0.0 0.022 14.4 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK68790.1 - 0.00012 22.2 0.0 0.043 13.8 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIK68790.1 - 0.064 13.3 0.1 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.15 KIK68790.1 - 0.23 10.7 0.0 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Methyltransf_31 PF13847.6 KIK68791.1 - 3.4e-29 101.6 0.0 4.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK68791.1 - 3.4e-24 85.4 0.0 5.9e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK68791.1 - 3.2e-21 75.8 0.0 5.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK68791.1 - 3.2e-16 59.4 0.0 5.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIK68791.1 - 7.3e-12 45.9 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK68791.1 - 4.1e-11 43.0 0.0 7.6e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK68791.1 - 1.7e-08 34.2 0.0 2.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KIK68791.1 - 5.7e-08 32.8 0.0 8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KIK68791.1 - 9.3e-08 31.8 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIK68791.1 - 7.9e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIK68791.1 - 2.9e-05 23.6 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.18 KIK68791.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 KIK68791.1 - 0.00018 21.4 1.5 0.00095 19.1 1.5 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_15 PF09445.10 KIK68791.1 - 0.0015 18.1 0.2 0.0031 17.1 0.1 1.5 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 KIK68791.1 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KIK68791.1 - 0.0047 16.3 0.0 0.0068 15.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 KIK68791.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein GidB PF02527.15 KIK68791.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 KIK68791.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KIK68791.1 - 0.029 13.8 0.0 0.38 10.2 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KIK68791.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KIK68791.1 - 0.14 11.9 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_9 PF08003.11 KIK68791.1 - 0.24 10.3 0.0 0.57 9.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) MFS_1 PF07690.16 KIK68793.1 - 4e-24 85.2 75.1 3.5e-18 65.6 48.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M48 PF01435.18 KIK68794.1 - 2.8e-28 99.0 0.1 8e-28 97.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 KIK68794.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) MR_MLE_C PF13378.6 KIK68798.1 - 4.8e-56 189.8 0.1 6e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIK68798.1 - 1.5e-20 73.5 0.0 3.7e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PWI PF01480.17 KIK68799.1 - 3.5e-28 97.7 0.1 5.4e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 PWI domain Glyco_hydro_61 PF03443.14 KIK68801.1 - 5.3e-62 209.4 0.0 8e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KIK68801.1 - 3.4e-14 52.5 12.3 1.1e-13 50.9 12.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 KIK68802.1 - 1.3e-62 211.4 0.1 2e-62 210.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KIK68802.1 - 3.7e-14 52.4 11.7 1.2e-13 50.7 11.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain EMP24_GP25L PF01105.24 KIK68803.1 - 3e-40 138.1 0.0 3.6e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 KIK68803.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif Cmc1 PF08583.10 KIK68804.1 - 0.00017 21.5 2.0 0.00024 21.0 2.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KIK68804.1 - 0.0005 20.3 0.5 0.00068 19.8 0.5 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KIK68804.1 - 0.0022 18.3 2.5 0.0036 17.6 2.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) NDUF_B7 PF05676.13 KIK68804.1 - 0.026 14.2 1.8 0.038 13.7 1.8 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KIK68804.1 - 0.12 12.7 1.0 0.17 12.2 1.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF1534 PF07551.11 KIK68805.1 - 0.053 13.3 0.4 0.11 12.3 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1534) CorA PF01544.18 KIK68807.1 - 5.6e-31 108.0 2.3 1.1e-27 97.2 1.5 2.5 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein SCAMP PF04144.13 KIK68807.1 - 0.016 15.5 0.8 0.027 14.8 0.8 1.2 1 0 0 1 1 1 0 SCAMP family DUF4660 PF15559.6 KIK68807.1 - 0.022 15.1 0.0 0.092 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Exonuc_VII_S PF02609.16 KIK68807.1 - 0.19 11.8 0.3 0.58 10.3 0.3 1.7 1 0 0 1 1 1 0 Exonuclease VII small subunit HTH_46 PF15977.5 KIK68808.1 - 0.065 13.3 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding SGIII PF15467.6 KIK68809.1 - 0.02 14.2 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 Secretogranin-3 p450 PF00067.22 KIK68810.1 - 6e-73 246.2 0.0 1.5e-72 244.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.22 KIK68812.1 - 6.2e-48 164.1 0.0 7.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KIK68813.1 - 2.6e-22 79.7 0.0 2.9e-21 76.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF455 PF04305.14 KIK68814.1 - 0.0007 19.2 0.6 0.0012 18.5 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) DUF745 PF05335.13 KIK68815.1 - 0.0067 16.2 1.6 2.1 8.0 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF745) DUF648 PF04890.13 KIK68815.1 - 0.037 13.8 0.2 0.055 13.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) PKcGMP_CC PF16808.5 KIK68815.1 - 0.65 9.9 7.4 5.5 6.9 0.3 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PhoLip_ATPase_C PF16212.5 KIK68817.1 - 3.4e-48 164.6 24.3 3.4e-48 164.6 24.3 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK68817.1 - 8.1e-17 60.7 3.1 2.2e-16 59.3 3.1 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIK68817.1 - 1e-14 55.3 0.0 6.6e-09 36.4 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK68817.1 - 5.3e-07 29.6 0.0 9.5e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIK68817.1 - 1.8e-05 24.3 3.5 0.00012 21.7 0.0 3.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIK68817.1 - 0.0055 16.5 0.1 0.014 15.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Palm_thioest PF02089.15 KIK68818.1 - 2.1e-80 270.1 0.0 2.4e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KIK68818.1 - 0.11 12.1 0.1 0.3 10.7 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold TRAPP PF04051.16 KIK68819.1 - 4.3e-37 127.1 0.0 5.2e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Med10 PF09748.9 KIK68821.1 - 4e-21 75.2 0.1 4.7e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 KIK68821.1 - 0.077 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 PIN domain Ribosomal_S13 PF00416.22 KIK68822.1 - 2.9e-50 169.9 1.1 3.3e-50 169.8 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 KIK68822.1 - 0.028 14.8 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Period_C PF12114.8 KIK68822.1 - 0.051 13.2 0.1 0.064 12.8 0.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region FbpA PF05833.11 KIK68822.1 - 0.069 11.9 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) NAD_kinase PF01513.21 KIK68823.1 - 5.3e-73 245.8 0.0 2.8e-72 243.4 0.0 2.1 2 1 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 KIK68823.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NOA36 PF06524.12 KIK68823.1 - 2 7.7 4.3 3.2 7.0 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein Hepatitis_core PF00906.20 KIK68823.1 - 5.5 6.5 6.6 18 4.8 1.4 2.6 2 0 0 2 2 2 0 Hepatitis core antigen Q_salvage PF10343.9 KIK68824.1 - 6.8e-11 42.3 0.0 4.1e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family YqeY PF09424.10 KIK68825.1 - 3.8e-26 91.9 0.4 4.3e-26 91.7 0.4 1.0 1 0 0 1 1 1 1 Yqey-like protein DNA_gyraseB_C PF00986.21 KIK68825.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus zf-rbx1 PF12678.7 KIK68826.1 - 7e-13 48.7 4.2 1.2e-12 47.9 4.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIK68826.1 - 1.5e-10 41.2 5.7 3e-10 40.3 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK68826.1 - 2.8e-07 30.3 3.5 5.1e-07 29.4 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK68826.1 - 4.5e-07 29.8 4.0 8.4e-07 28.9 4.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK68826.1 - 8.6e-07 28.7 3.3 8.6e-07 28.7 3.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK68826.1 - 2.4e-06 27.5 0.8 4.3e-06 26.7 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIK68826.1 - 4.3e-05 23.3 3.8 0.00065 19.5 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK68826.1 - 5e-05 23.1 1.8 0.00012 21.9 1.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK68826.1 - 0.00044 20.1 3.2 0.00085 19.2 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KIK68826.1 - 0.00049 19.7 0.6 0.0011 18.5 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KIK68826.1 - 0.0025 17.5 2.8 0.0042 16.8 0.4 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KIK68826.1 - 0.0084 16.3 1.6 0.021 15.0 1.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KIK68826.1 - 0.072 13.3 0.6 0.15 12.3 0.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 KIK68826.1 - 0.21 11.8 0.4 0.37 11.0 0.4 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain TFIIA PF03153.13 KIK68826.1 - 0.24 11.3 5.0 0.32 10.9 5.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING-like PF08746.11 KIK68826.1 - 0.34 11.3 2.5 0.66 10.3 2.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KIK68826.1 - 0.68 9.8 3.1 0.63 9.9 1.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.11 KIK68827.1 - 2.2e-88 297.8 0.0 2.7e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIK68827.1 - 1.2e-11 44.6 0.0 6.2e-10 38.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family SNF2_N PF00176.23 KIK68828.1 - 1.1e-49 169.1 0.0 1.8e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK68828.1 - 8.3e-13 48.7 0.0 1.8e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK68828.1 - 7.8e-11 42.3 0.0 2.2e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK68828.1 - 6.3e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KIK68828.1 - 0.015 14.2 0.0 0.052 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 DUF2439 PF10382.9 KIK68828.1 - 0.016 15.5 0.1 1 9.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) HDA2-3 PF11496.8 KIK68828.1 - 0.053 12.7 0.1 0.098 11.8 0.1 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TIP49 PF06068.13 KIK68829.1 - 8.8e-158 525.1 0.0 1e-157 524.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIK68829.1 - 1e-19 70.4 0.1 2.2e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KIK68829.1 - 7.1e-10 39.4 0.0 2.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIK68829.1 - 1.2e-08 34.9 0.0 6.5e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK68829.1 - 3.7e-06 27.3 0.2 0.096 13.0 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK68829.1 - 4.2e-06 27.3 0.1 4.9e-05 23.8 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 KIK68829.1 - 8.9e-06 25.7 0.1 0.006 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KIK68829.1 - 0.0016 18.7 0.0 0.0095 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK68829.1 - 0.002 17.7 0.0 0.0048 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK68829.1 - 0.0026 18.1 0.6 0.026 14.9 0.6 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK68829.1 - 0.029 13.7 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIK68829.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KIK68829.1 - 0.057 13.6 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIK68829.1 - 0.065 12.9 0.0 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIK68829.1 - 0.067 12.7 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIK68829.1 - 0.069 13.7 0.1 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK68829.1 - 0.072 12.4 0.1 0.27 10.5 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 KIK68829.1 - 0.15 12.0 0.0 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CSTF_C PF14304.6 KIK68830.1 - 7.9e-13 47.8 0.5 7.9e-13 47.8 0.5 1.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KIK68830.1 - 4.6e-09 36.6 4.9 4.6e-09 36.6 4.9 2.8 2 1 1 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 DUF4587 PF15248.6 KIK68830.1 - 0.064 14.1 0.1 0.064 14.1 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4587) UBM PF14377.6 KIK68830.1 - 8.7 5.9 9.3 5.1 6.7 4.0 2.5 2 0 0 2 2 2 0 Ubiquitin binding region SNF2_N PF00176.23 KIK68831.1 - 6.4e-62 209.3 0.1 9.3e-47 159.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain HAND PF09110.11 KIK68831.1 - 6.1e-32 110.7 0.9 6.1e-32 110.7 0.9 4.0 4 1 0 4 4 4 1 HAND SLIDE PF09111.10 KIK68831.1 - 7.3e-31 106.5 2.0 1.3e-14 54.1 0.0 3.0 3 0 0 3 3 3 2 SLIDE UPF0086 PF01868.16 KIK68831.1 - 1.7e-25 88.7 0.0 3.6e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Helicase_C PF00271.31 KIK68831.1 - 3e-17 63.0 0.0 1.2e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK68831.1 - 2.1e-06 27.8 0.0 9.5e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK68831.1 - 0.00018 20.8 0.0 0.00052 19.3 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIK68831.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_14 PF13173.6 KIK68831.1 - 0.084 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain tRNA-synt_2c PF01411.19 KIK68832.1 - 3.9e-217 722.1 0.0 5.7e-217 721.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIK68832.1 - 8.3e-18 64.2 0.1 2.1e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KIK68832.1 - 2e-12 47.7 3.0 2e-12 47.7 3.0 1.9 2 0 0 2 2 2 1 DHHA1 domain Glyco_transf_88 PF16849.5 KIK68832.1 - 0.014 14.3 1.1 0.023 13.7 1.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 Stk19 PF10494.9 KIK68832.1 - 0.37 10.5 2.9 2.2 7.9 2.9 2.0 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 TPX2 PF06886.11 KIK68832.1 - 9.7 6.5 10.3 0.76 10.1 4.5 2.1 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Nucleos_tra2_C PF07662.13 KIK68833.1 - 5.9e-68 228.8 7.4 5.9e-68 228.8 7.4 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KIK68833.1 - 1.6e-20 73.4 4.9 1.6e-20 73.4 4.9 4.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KIK68833.1 - 0.41 10.9 21.2 0.39 11.0 5.8 3.4 3 1 0 3 3 3 0 Nucleoside recognition WD40 PF00400.32 KIK68834.1 - 9.3e-10 39.0 6.6 0.00022 22.0 0.1 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat DUF3712 PF12505.8 KIK68835.1 - 3.1e-110 363.5 77.9 1.3e-25 90.0 0.1 11.5 12 0 0 12 12 12 7 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KIK68835.1 - 3e-08 34.1 19.9 0.52 10.9 0.1 9.1 8 0 0 8 8 8 4 Late embryogenesis abundant protein Adaptin_N PF01602.20 KIK68837.1 - 5.7e-79 266.0 4.5 8.2e-79 265.5 4.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KIK68837.1 - 2.4e-60 202.1 0.0 5.2e-60 201.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KIK68837.1 - 1.1e-53 180.9 0.0 2.6e-53 179.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KIK68837.1 - 1.5e-07 31.7 0.1 0.0044 17.4 0.0 4.2 1 1 3 4 4 4 3 HEAT repeats Cnd1 PF12717.7 KIK68837.1 - 2.1e-05 24.6 1.9 0.0014 18.7 0.1 3.3 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK68837.1 - 4.5e-05 23.4 0.1 0.69 10.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 KIK68837.1 - 0.00011 22.3 0.1 0.00077 19.6 0.0 2.5 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform RTP1_C1 PF10363.9 KIK68837.1 - 0.00095 19.3 1.0 0.13 12.5 0.0 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 KIK68837.1 - 0.002 18.2 1.0 0.96 9.5 0.0 3.1 3 0 0 3 3 3 2 Parkin co-regulated protein DUF5578 PF17741.1 KIK68837.1 - 0.012 15.0 2.5 0.034 13.6 0.9 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5578) Gemini_V2 PF01524.17 KIK68837.1 - 0.016 15.4 0.0 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 Geminivirus V2 protein CLASP_N PF12348.8 KIK68838.1 - 3.4e-28 98.8 0.0 3.8e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal SecY PF00344.20 KIK68839.1 - 6e-73 245.8 11.4 7.5e-73 245.4 11.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KIK68839.1 - 3.7e-19 68.2 1.0 2.2e-18 65.8 0.2 2.7 3 0 0 3 3 3 1 Plug domain of Sec61p Prokineticin PF06607.11 KIK68839.1 - 0.43 10.9 1.3 14 6.1 0.4 3.1 3 1 0 3 3 3 0 Prokineticin Ribosomal_L34 PF00468.17 KIK68840.1 - 3.5e-21 74.9 10.8 4.4e-21 74.6 10.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 ATG7_N PF16420.5 KIK68841.1 - 1.2e-84 284.6 0.0 1.5e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KIK68841.1 - 3.8e-44 150.9 0.0 5.7e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family SCO1-SenC PF02630.14 KIK68842.1 - 1.5e-44 151.2 0.0 2.2e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KIK68842.1 - 0.00013 21.9 0.0 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KIK68842.1 - 0.0023 18.2 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like PPR_2 PF13041.6 KIK68843.1 - 1.1e-38 131.2 6.2 1.5e-09 37.9 0.0 10.8 11 1 1 12 12 12 7 PPR repeat family PPR PF01535.20 KIK68843.1 - 1e-31 107.0 21.2 1.1e-05 25.4 0.0 12.9 15 1 0 15 15 15 6 PPR repeat PPR_1 PF12854.7 KIK68843.1 - 1.4e-21 75.9 3.0 0.0052 16.4 0.0 9.3 10 0 0 10 10 10 6 PPR repeat PPR_3 PF13812.6 KIK68843.1 - 2.3e-15 56.4 2.8 6.1e-07 29.4 0.0 8.0 7 1 1 9 9 9 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KIK68843.1 - 1.5e-13 50.6 2.5 1.9e-08 33.9 0.6 4.4 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIK68843.1 - 0.00014 22.4 7.4 5.8 8.0 0.0 8.3 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68843.1 - 0.018 15.0 0.3 3.9 7.7 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68843.1 - 0.13 12.8 7.8 11 6.6 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK68843.1 - 0.24 11.3 2.9 2.2 8.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat VWA_2 PF13519.6 KIK68844.1 - 2.4e-26 92.4 1.2 2.2e-24 86.1 0.1 2.9 3 0 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 KIK68844.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KIK68844.1 - 0.0018 18.1 4.0 0.0018 18.1 4.0 4.3 5 0 0 5 5 5 3 Ubiquitin interaction motif RAP80_UIM PF18282.1 KIK68844.1 - 0.4 10.5 12.1 1.1 9.1 0.2 3.6 3 1 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif PET117 PF15786.5 KIK68845.1 - 2.4 8.5 5.7 2.6 8.3 0.2 2.2 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial ATXN-1_C PF12547.8 KIK68845.1 - 3 8.2 8.4 2 8.8 1.2 2.6 2 1 0 2 2 2 0 Capicua transcriptional repressor modulator Amidohydro_3 PF07969.11 KIK68846.1 - 1.2e-19 71.2 0.0 3.5e-18 66.3 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK68846.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family DUF2070 PF09843.9 KIK68847.1 - 2.3 6.4 4.9 0.47 8.7 1.7 1.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) UCH PF00443.29 KIK68849.1 - 2.4e-64 217.3 0.0 3.5e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK68849.1 - 2e-17 63.8 0.0 3.5e-16 59.7 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KIK68849.1 - 8.3e-05 23.1 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 KIK68849.1 - 0.069 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Peptidase_C98 PF15499.6 KIK68849.1 - 0.12 11.8 0.5 1.8 8.0 0.1 2.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase NfeD PF01957.18 KIK68850.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.6 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding PRP3 PF08572.10 KIK68851.1 - 6.9e-69 232.0 3.4 1.2e-68 231.2 3.4 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KIK68851.1 - 5.5e-45 153.1 0.0 5.5e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosomal_L16 PF00252.18 KIK68852.1 - 2.3e-38 131.2 0.2 2.6e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Gene66 PF02053.15 KIK68853.1 - 0.028 14.1 0.4 0.051 13.2 0.4 1.6 1 1 0 1 1 1 0 Gene 66 (IR5) protein Peptidase_S49_N PF08496.10 KIK68854.1 - 0.079 13.0 5.5 0.13 12.3 5.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 KIK68854.1 - 1.1 8.1 4.8 1.7 7.5 4.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dynamin_N PF00350.23 KIK68855.1 - 4.5e-41 140.7 0.0 9.9e-41 139.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIK68855.1 - 7.7e-09 35.2 0.0 3e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KIK68855.1 - 6.1e-05 23.1 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KIK68855.1 - 0.045 13.5 0.6 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK68855.1 - 0.062 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain FAD_binding_3 PF01494.19 KIK68856.1 - 4.8e-29 101.7 0.0 6.6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK68856.1 - 1.2e-07 31.3 0.3 0.0095 15.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK68856.1 - 2.9e-05 23.8 0.2 0.0093 15.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 KIK68856.1 - 5.7e-05 22.3 0.0 0.00027 20.1 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 KIK68856.1 - 0.0083 16.7 0.1 1.6 9.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK68856.1 - 0.012 15.0 0.1 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIK68856.1 - 0.019 14.0 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK68856.1 - 0.037 13.1 0.3 0.86 8.6 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KIK68856.1 - 0.069 13.1 1.0 0.32 11.0 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK68856.1 - 0.095 11.9 0.6 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK68856.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK68856.1 - 0.13 10.9 0.1 5.7 5.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_transf_11 PF01531.16 KIK68856.1 - 0.21 10.7 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 FA_hydroxylase PF04116.13 KIK68857.1 - 1.6e-21 77.1 17.4 1.6e-21 77.1 17.4 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Transferase PF02458.15 KIK68858.1 - 1.1e-30 106.7 0.0 3e-17 62.4 0.0 3.2 2 1 0 2 2 2 2 Transferase family Med1 PF10744.9 KIK68860.1 - 0.099 11.7 0.1 3.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 AT_hook PF02178.19 KIK68865.1 - 0.04 13.8 2.1 0.21 11.6 2.1 2.4 1 0 0 1 1 1 0 AT hook motif GIY-YIG PF01541.24 KIK68866.1 - 4.8e-11 42.8 0.0 1.4e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KIK68866.1 - 0.019 15.2 0.2 0.043 14.1 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 KIK68866.1 - 0.15 12.2 1.6 0.36 11.0 1.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 KIK68866.1 - 1.3 9.4 5.8 2.9 8.3 5.8 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3989 PF13150.6 KIK68867.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) HSP70 PF00012.20 KIK68869.1 - 3.5e-241 801.6 8.7 4.3e-241 801.3 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK68869.1 - 7.8e-19 67.7 0.3 2.4e-17 62.7 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KIK68869.1 - 0.00014 22.2 1.7 0.59 10.6 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KIK68869.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KIK68869.1 - 0.019 14.0 0.4 0.21 10.5 0.4 2.3 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FliS PF02561.14 KIK68869.1 - 0.11 12.8 1.6 0.26 11.6 1.6 1.6 1 0 0 1 1 1 0 Flagellar protein FliS PMC2NT PF08066.12 KIK68869.1 - 0.36 11.5 3.1 1.6 9.5 3.1 2.1 1 1 0 1 1 1 0 PMC2NT (NUC016) domain GAS PF13851.6 KIK68869.1 - 1.8 7.9 10.2 0.59 9.5 0.2 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding zf-CCCH PF00642.24 KIK68870.1 - 1.1e-13 50.7 16.5 4.6e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KIK68870.1 - 0.003 17.3 0.0 0.0085 15.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KIK68870.1 - 0.0064 16.5 3.3 0.0064 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KIK68870.1 - 0.0081 16.8 2.3 1.6 9.5 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KIK68870.1 - 0.014 15.6 4.1 0.25 11.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger containing family MFS_1 PF07690.16 KIK68871.1 - 1.1e-17 64.0 50.2 4.4e-15 55.5 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MMS19_N PF14500.6 KIK68871.1 - 0.003 17.2 0.1 0.0045 16.6 0.1 1.1 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Cyclin PF08613.11 KIK68872.1 - 6.6e-30 104.6 0.3 1.9e-29 103.1 0.2 1.7 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIK68872.1 - 6e-05 22.8 0.1 8.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.14 KIK68873.1 - 4.1e-24 84.2 0.1 9.7e-24 83.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KIK68873.1 - 1.6e-16 60.5 0.1 2.9e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Esterase_phd PF10503.9 KIK68874.1 - 1.8e-07 30.9 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KIK68874.1 - 0.0038 16.5 0.0 1.2 8.4 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KIK68874.1 - 0.055 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF1507 PF07408.11 KIK68875.1 - 0.12 12.3 0.6 4.6 7.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1507) Abhydrolase_3 PF07859.13 KIK68876.1 - 5.8e-45 153.7 0.0 7.9e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK68876.1 - 6.4e-08 31.9 0.0 1.4e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 KIK68876.1 - 0.0037 17.4 0.0 0.0081 16.3 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain AXE1 PF05448.12 KIK68876.1 - 0.0069 15.1 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KIK68876.1 - 0.0088 15.5 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 KIK68876.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KIK68876.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KIK68876.1 - 0.096 12.3 0.1 0.34 10.5 0.1 1.8 1 1 0 1 1 1 0 Putative esterase adh_short_C2 PF13561.6 KIK68877.1 - 2.9e-61 207.0 2.1 3.3e-61 206.8 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK68877.1 - 6.8e-48 162.7 2.2 8.1e-48 162.5 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK68877.1 - 4.5e-09 36.5 0.5 6.3e-09 36.0 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK68877.1 - 6.7e-05 22.5 0.2 0.00017 21.1 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIK68877.1 - 0.0033 16.7 1.6 0.0053 16.1 1.6 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KIK68877.1 - 0.055 12.6 0.6 0.074 12.2 0.6 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MTES_1575 PF18741.1 KIK68877.1 - 0.082 13.1 0.1 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 REase_MTES_1575 Med14 PF08638.11 KIK68878.1 - 6.9e-65 218.0 1.6 8.9e-65 217.7 0.1 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 CbiG_mid PF11761.8 KIK68878.1 - 0.12 12.5 0.1 19 5.4 0.0 2.9 3 0 0 3 3 3 0 Cobalamin biosynthesis central region HEAT PF02985.22 KIK68879.1 - 8.8e-10 38.0 0.1 0.067 13.5 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KIK68879.1 - 2.3e-05 24.5 0.1 0.064 13.3 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 KIK68879.1 - 0.00015 21.2 0.0 0.00079 18.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68879.1 - 0.00024 20.5 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KIK68879.1 - 0.00048 20.5 0.1 0.8 10.1 0.0 3.6 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KIK68879.1 - 0.0009 19.7 0.7 0.52 10.9 0.1 4.4 3 2 2 5 5 5 1 HEAT-like repeat Kinase-like PF14531.6 KIK68879.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DASH_Dad2 PF08654.10 KIK68881.1 - 7e-06 26.4 0.1 8.8e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 DASH complex subunit Dad2 Peptidase_C25 PF01364.18 KIK68881.1 - 0.0088 15.3 0.0 0.0096 15.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C25 Med12 PF09497.10 KIK68882.1 - 2.4e-26 91.8 0.1 6.7e-26 90.4 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KIK68882.1 - 8.4e-06 24.9 0.0 0.0001 21.4 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DNA_pol_lambd_f PF10391.9 KIK68882.1 - 0.077 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda zf-C3HC4 PF00097.25 KIK68883.1 - 7.6e-06 25.7 6.6 1.9e-05 24.5 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK68883.1 - 2.6e-05 24.0 6.6 0.00063 19.6 1.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK68883.1 - 5.7e-05 23.4 8.0 0.00099 19.4 4.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK68883.1 - 6.8e-05 22.6 2.4 6.8e-05 22.6 2.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK68883.1 - 0.00022 21.1 7.7 0.0058 16.6 7.7 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK68883.1 - 0.00023 21.2 2.5 0.00023 21.2 2.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIK68883.1 - 0.0003 20.7 3.8 0.0003 20.7 3.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK68883.1 - 0.0047 16.8 7.6 0.01 15.7 1.5 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-HIT PF04438.16 KIK68883.1 - 0.29 11.0 0.2 0.29 11.0 0.2 2.7 2 1 0 2 2 2 0 HIT zinc finger C1_2 PF03107.16 KIK68883.1 - 0.44 10.9 6.5 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 C1 domain Zn_ribbon_17 PF17120.5 KIK68883.1 - 0.53 9.9 6.6 0.17 11.5 3.1 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KIK68883.1 - 1.1 9.6 10.7 0.15 12.4 2.6 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain FANCL_C PF11793.8 KIK68883.1 - 2 8.6 7.6 0.32 11.2 1.9 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 KIK68883.1 - 2.8 8.0 7.6 1.1e+02 2.9 7.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon PWWP PF00855.17 KIK68884.1 - 2.7e-12 46.9 0.0 1.8e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 PWWP domain Chromo PF00385.24 KIK68884.1 - 0.0035 17.2 2.1 0.0066 16.3 2.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KIK68884.1 - 0.0051 16.7 0.3 0.014 15.3 0.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DNA_primase_S PF01896.19 KIK68885.1 - 7.5e-56 189.0 0.4 1e-55 188.5 0.4 1.2 1 0 0 1 1 1 1 DNA primase small subunit Peroxidase_ext PF11895.8 KIK68886.1 - 1.7e-27 95.1 2.1 3.7e-27 94.1 2.1 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KIK68886.1 - 6.5e-27 94.7 0.0 9.6e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Adaptin_N PF01602.20 KIK68889.1 - 7.5e-24 84.2 0.1 3.2e-23 82.1 0.1 1.9 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KIK68889.1 - 0.00041 20.4 0.1 0.036 14.1 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK68889.1 - 0.0008 19.7 3.1 0.064 13.7 0.2 4.1 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KIK68889.1 - 0.0016 18.9 0.1 0.2 12.2 0.1 3.8 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KIK68889.1 - 0.0066 16.6 0.1 0.16 12.3 0.1 3.5 4 0 0 4 4 4 1 HEAT repeat Cohesin_HEAT PF12765.7 KIK68889.1 - 0.057 13.7 2.7 13 6.1 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion RabGAP-TBC PF00566.18 KIK68890.1 - 1.2e-41 142.8 0.1 1.6e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPR_2 PF07719.17 KIK68891.1 - 9.3e-32 106.6 17.9 1.2e-07 31.3 0.1 9.2 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIK68891.1 - 6.5e-27 92.2 17.0 1.1e-09 37.6 0.1 8.7 10 0 0 10 10 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK68891.1 - 1.4e-25 89.3 7.7 8.9e-11 41.9 0.0 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIK68891.1 - 6.3e-23 79.0 3.8 4e-08 32.8 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIK68891.1 - 2.1e-19 69.9 1.1 2.3e-06 28.1 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK68891.1 - 2.4e-18 66.2 22.2 2.4e-12 47.0 1.1 8.2 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68891.1 - 3.9e-17 62.5 7.6 1.2e-05 25.7 0.3 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68891.1 - 1.3e-12 46.8 13.0 0.001 19.0 0.2 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KIK68891.1 - 1.2e-10 41.3 17.6 0.00017 22.0 0.1 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK68891.1 - 2.2e-10 40.2 8.8 0.28 11.6 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK68891.1 - 8.6e-10 38.1 9.2 0.00075 19.1 0.3 6.6 7 1 1 8 8 8 3 TPR repeat TPR_9 PF13371.6 KIK68891.1 - 1e-09 38.4 6.3 0.02 15.0 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK68891.1 - 7.2e-08 32.6 15.7 0.38 11.7 0.1 8.0 6 3 3 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK68891.1 - 9.2e-08 31.7 13.9 0.0063 16.4 0.6 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK68891.1 - 0.00019 20.9 2.6 0.076 12.4 0.2 3.4 3 0 0 3 3 3 2 MalT-like TPR region TPR_3 PF07720.12 KIK68891.1 - 0.0013 18.7 10.5 0.33 11.0 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 KIK68891.1 - 0.0013 18.2 0.2 0.059 12.8 0.2 2.9 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 KIK68891.1 - 0.0017 18.4 4.0 3.1 7.9 0.3 5.1 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat HemY_N PF07219.13 KIK68891.1 - 0.18 12.0 0.2 9.5 6.5 0.1 3.2 3 0 0 3 3 3 0 HemY protein N-terminus MIT PF04212.18 KIK68891.1 - 0.51 10.5 2.4 1.8 8.7 0.1 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain WD40 PF00400.32 KIK68892.1 - 7.2e-44 146.9 26.5 2.4e-08 34.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK68892.1 - 1.8e-09 37.8 0.9 0.17 12.2 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK68892.1 - 0.00055 19.8 1.7 2.9 7.9 0.0 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK68892.1 - 0.00088 18.0 8.4 0.065 11.9 0.2 4.3 4 1 1 5 5 5 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KIK68892.1 - 0.0036 16.4 0.0 0.35 9.9 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KIK68892.1 - 0.019 13.5 0.1 1.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain zf-C2H2 PF00096.26 KIK68895.1 - 4.9e-08 33.0 14.8 1.6e-05 25.1 6.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK68895.1 - 2.3e-06 27.8 15.8 2.8e-05 24.3 4.2 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 KIK68895.1 - 0.002 17.8 3.7 0.0039 16.9 3.7 1.5 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KIK68895.1 - 0.0056 17.4 12.6 0.013 16.2 4.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIK68895.1 - 0.042 14.2 7.9 0.2 12.1 3.1 2.5 2 1 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KIK68895.1 - 0.085 13.5 5.7 1 10.1 0.7 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain IU_nuc_hydro PF01156.19 KIK68896.1 - 1.5e-58 198.8 0.0 2.1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Got1 PF04178.12 KIK68897.1 - 7.1e-20 71.5 13.7 9.8e-20 71.1 13.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DIOX_N PF14226.6 KIK68898.1 - 1.5e-17 64.4 0.0 2.8e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK68898.1 - 2.9e-16 59.8 0.0 5.2e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily U3_assoc_6 PF08640.11 KIK68900.1 - 1.7e-12 47.2 5.2 6.1e-10 39.0 1.1 3.5 2 1 1 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KIK68900.1 - 9.1e-05 23.0 1.6 2.7 9.0 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat Pkinase PF00069.25 KIK68901.1 - 1.7e-33 116.1 0.0 8.4e-32 110.6 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68901.1 - 1.5e-17 63.7 0.0 2.6e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK68901.1 - 0.099 11.9 0.0 0.29 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like CHIPS PF11434.8 KIK68903.1 - 0.073 12.9 0.1 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS Acetyltransf_10 PF13673.7 KIK68904.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK68904.1 - 2.1e-08 34.4 0.0 2.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK68904.1 - 4.3e-07 30.3 0.0 7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK68904.1 - 1.6e-05 24.8 0.0 5.4e-05 23.1 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KIK68904.1 - 0.00019 21.5 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 KIK68904.1 - 0.099 12.9 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region PEPCK_ATP PF01293.20 KIK68905.1 - 1.6e-210 699.7 0.0 5.4e-209 694.6 0.0 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KIK68905.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK68905.1 - 0.12 12.2 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF21 PF01595.20 KIK68906.1 - 1.4e-33 116.1 0.1 2.3e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIK68906.1 - 0.0037 17.7 0.8 20 5.8 0.0 3.6 3 0 0 3 3 3 2 CBS domain CENP-T_C PF15511.6 KIK68907.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK68907.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK68907.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK68907.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK68907.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK68907.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit YCII PF03795.14 KIK68911.1 - 3.9e-07 30.4 0.0 5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain TssR PF17643.1 KIK68911.1 - 0.14 10.1 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssR YCII PF03795.14 KIK68912.1 - 0.0043 17.4 0.0 0.006 17.0 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.14 KIK68913.1 - 0.00012 22.4 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain ECH_1 PF00378.20 KIK68914.1 - 2e-83 279.5 0.6 2.4e-83 279.3 0.6 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK68914.1 - 3.2e-33 115.6 0.6 1.2e-30 107.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIK68914.1 - 0.0063 16.5 0.1 0.055 13.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 DUF4536 PF15055.6 KIK68915.1 - 8.4e-07 29.1 1.3 1.2e-06 28.7 1.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) p450 PF00067.22 KIK68917.1 - 4.8e-74 249.8 0.0 2.6e-73 247.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 NCE101 PF11654.8 KIK68917.1 - 0.034 13.8 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 Phage_SSB PF16773.5 KIK68917.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein O-FucT PF10250.9 KIK68918.1 - 1.9e-09 37.7 0.0 9.7e-05 22.2 0.0 3.0 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SAM_2 PF07647.17 KIK68919.1 - 6.1e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIK68919.1 - 6.9e-06 26.4 0.1 1.4e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5393 PF17371.2 KIK68919.1 - 0.0014 16.8 4.3 0.0021 16.3 4.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5393) SAM_3 PF18016.1 KIK68919.1 - 0.019 14.8 0.1 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KIK68919.1 - 0.15 12.4 0.8 0.23 11.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) IGR PF09597.10 KIK68919.1 - 0.18 11.9 1.0 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 IGR protein motif MID_MedPIWI PF18296.1 KIK68919.1 - 1.7 8.4 5.1 0.3 10.9 1.5 1.6 2 0 0 2 2 2 0 MID domain of medPIWI DUF1932 PF09130.11 KIK68920.1 - 3.6e-18 65.3 0.1 1.1e-17 63.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KIK68920.1 - 1e-06 29.0 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIK68920.1 - 0.0002 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KIK68920.1 - 0.0013 19.3 0.2 0.0048 17.5 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KIK68920.1 - 0.0029 17.5 0.1 0.0059 16.5 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIK68920.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XPC-binding PF09280.11 KIK68920.1 - 0.051 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 XPC-binding domain ATP-synt_ab PF00006.25 KIK68920.1 - 0.071 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ApbA PF02558.16 KIK68920.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PSII_Pbs27 PF13326.6 KIK68920.1 - 0.11 12.8 0.3 0.31 11.4 0.2 1.8 2 0 0 2 2 2 0 Photosystem II Pbs27 3HCDH_N PF02737.18 KIK68920.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MyTH4 PF00784.17 KIK68921.1 - 6.8e-30 103.7 0.0 1.6e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 KIK68921.1 - 2e-27 95.9 0.0 3.6e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KIK68921.1 - 7.2e-10 38.8 4.1 0.00011 22.2 2.6 2.5 2 0 0 2 2 2 2 WW domain TAN PF11640.8 KIK68922.1 - 0.018 15.2 3.0 0.021 14.9 0.1 2.4 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair MLTR_LBD PF17765.1 KIK68922.1 - 0.055 13.6 0.3 0.29 11.3 0.1 2.2 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Hydrolase_like PF13242.6 KIK68923.1 - 1.3e-22 79.7 0.0 3.5e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIK68923.1 - 3.7e-18 65.5 0.0 6.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK68923.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK68923.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 KIK68924.1 - 1.1e-07 31.8 12.7 2.6e-07 30.6 12.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KIK68924.1 - 3e-06 27.4 11.6 0.019 15.4 0.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK68924.1 - 3.8e-05 23.9 2.1 3.8e-05 23.9 2.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain His_kinase PF06580.13 KIK68924.1 - 0.0015 18.8 0.1 0.0031 17.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase zf-C2H2_4 PF13894.6 KIK68924.1 - 0.0059 17.3 16.7 0.15 13.0 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK68924.1 - 0.03 14.1 5.1 0.36 10.6 0.4 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KIK68924.1 - 0.21 11.6 4.3 0.42 10.7 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF218 PF02698.17 KIK68925.1 - 4.4e-05 23.5 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain Git3 PF11710.8 KIK68926.1 - 7e-10 39.0 7.1 1.3e-09 38.1 7.1 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KIK68926.1 - 0.0036 16.5 6.5 0.0057 15.8 6.5 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Cadherin_C_2 PF16492.5 KIK68926.1 - 0.31 11.8 3.2 1 10.1 3.2 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Ferric_reduct PF01794.19 KIK68926.1 - 1.6 8.9 10.6 0.11 12.6 0.6 3.1 3 0 0 3 3 3 0 Ferric reductase like transmembrane component Fungal_trans PF04082.18 KIK68929.1 - 2.6e-07 30.0 0.3 5.2e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK68929.1 - 2.1e-05 24.5 11.3 3.5e-05 23.8 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.16 KIK68930.1 - 5.1e-25 88.4 16.8 7.1e-25 87.9 16.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK68930.1 - 6.8e-06 26.3 35.8 0.0002 21.5 12.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIK68930.1 - 0.002 17.4 18.5 0.0032 16.7 18.5 1.4 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KIK68930.1 - 0.0036 16.6 17.5 0.0066 15.7 16.0 2.1 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Med31 PF05669.12 KIK68931.1 - 4.7e-34 116.3 9.3 7.2e-34 115.7 9.3 1.3 1 0 0 1 1 1 1 SOH1 Peptidase_C12 PF01088.21 KIK68932.1 - 7.7e-51 172.8 0.0 1.3e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KIK68932.1 - 3e-13 49.4 0.8 6.8e-13 48.3 0.8 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Peptidase_M19 PF01244.21 KIK68933.1 - 5e-104 347.9 0.0 6.1e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA_18 PF13238.6 KIK68934.1 - 1.7e-08 35.0 0.0 5.3e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK68934.1 - 0.001 19.3 0.0 0.0046 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIK68934.1 - 0.0023 17.3 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KIK68934.1 - 0.032 14.5 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KIK68934.1 - 0.077 12.4 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FAD_binding_2 PF00890.24 KIK68935.1 - 8.8e-90 301.8 1.9 8.8e-90 301.8 1.9 1.4 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 KIK68935.1 - 6.4e-23 80.7 0.0 4.1e-22 78.1 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KIK68935.1 - 3.5e-14 53.2 1.2 9.1e-14 51.8 1.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK68935.1 - 8.3e-13 48.2 0.8 4.1e-10 39.4 0.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK68935.1 - 4.1e-10 39.7 0.2 2.8e-09 37.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIK68935.1 - 2.1e-09 37.3 3.7 6.3e-09 35.7 3.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK68935.1 - 6.1e-07 28.5 5.9 0.00013 20.8 0.4 3.3 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KIK68935.1 - 2.5e-06 26.9 3.9 9.7e-05 21.6 0.8 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIK68935.1 - 1.5e-05 24.4 1.1 2.4e-05 23.7 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIK68935.1 - 2.2e-05 23.8 1.5 0.011 15.0 0.5 3.1 2 1 1 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.6 KIK68935.1 - 4.2e-05 23.0 0.2 0.15 11.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK68935.1 - 0.00012 21.6 2.9 0.0044 16.4 0.3 2.8 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIK68935.1 - 0.00052 19.4 0.2 0.0011 18.3 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KIK68935.1 - 0.0015 19.0 1.4 0.053 14.1 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK68935.1 - 0.0018 18.3 1.2 0.019 15.0 1.2 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK68935.1 - 0.0063 15.6 0.7 0.04 13.0 0.5 2.0 1 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KIK68935.1 - 0.024 15.1 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GMC_oxred_N PF00732.19 KIK68935.1 - 0.07 12.5 0.3 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.6 KIK68935.1 - 0.16 11.1 0.1 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Apolipoprotein PF01442.18 KIK68936.1 - 0.00095 19.1 6.9 0.0015 18.5 6.8 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KIK68936.1 - 0.028 15.0 15.3 0.079 13.6 8.3 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) V-ATPase_G_2 PF16999.5 KIK68936.1 - 7.6 7.0 17.2 80 3.7 13.1 2.8 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit G-alpha PF00503.20 KIK68937.1 - 2e-103 346.3 0.0 9.2e-103 344.1 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK68937.1 - 9.4e-09 35.0 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DNA_pol_B_exo1 PF03104.19 KIK68938.1 - 4e-42 144.6 0.4 5.6e-42 144.1 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 KIK68938.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.6 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB PAXX PF15384.6 KIK68940.1 - 0.71 9.5 5.1 1.3 8.7 5.1 1.4 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 NTP_transferase PF00483.23 KIK68941.1 - 2.1e-41 142.2 0.0 4e-41 141.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIK68941.1 - 2.5e-07 31.2 0.1 5.6e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KIK68941.1 - 0.00018 21.5 0.1 0.00029 20.7 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.19 KIK68941.1 - 0.03 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NUDE_C PF04880.13 KIK68941.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DivIC PF04977.15 KIK68941.1 - 0.17 11.7 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF364 PF04016.12 KIK68941.1 - 0.18 11.4 0.1 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation Cupin_2 PF07883.11 KIK68942.1 - 1.3e-06 28.0 0.3 2.3e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 Cupin domain Lyx_isomer PF07385.12 KIK68942.1 - 0.0024 17.2 0.1 0.005 16.1 0.1 1.5 1 1 0 1 1 1 1 D-lyxose isomerase AraC_binding PF02311.19 KIK68942.1 - 0.0028 17.6 0.6 0.0045 16.9 0.6 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain AA_permease PF00324.21 KIK68943.1 - 4.1e-120 401.6 44.8 5.2e-120 401.3 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK68943.1 - 2.6e-29 102.3 51.3 3.2e-29 102.0 51.3 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KIK68943.1 - 0.068 13.9 0.6 0.068 13.9 0.6 3.8 4 1 0 4 4 4 0 PrgI family protein Corona_nucleoca PF00937.18 KIK68944.1 - 0.16 11.0 1.5 0.17 10.9 1.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Period_C PF12114.8 KIK68944.1 - 0.52 9.9 7.6 0.56 9.8 7.6 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Herpes_capsid PF06112.11 KIK68944.1 - 0.97 9.5 10.1 1.1 9.4 10.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PAP1 PF08601.10 KIK68944.1 - 1.6 8.4 8.4 1.9 8.1 8.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Glycophorin_A PF01102.18 KIK68945.1 - 2.6e-06 27.7 0.0 5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 KIK68945.1 - 0.0029 17.5 0.9 0.0049 16.7 0.9 1.3 1 0 0 1 1 1 1 Syndecan domain Rax2 PF12768.7 KIK68945.1 - 0.015 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Insulin_TMD PF17870.1 KIK68945.1 - 0.064 13.3 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RCR PF12273.8 KIK68945.1 - 0.075 13.7 0.1 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red VSP PF03302.13 KIK68945.1 - 0.077 11.8 1.3 0.1 11.4 1.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TraL PF07178.11 KIK68945.1 - 0.13 12.7 0.3 0.24 11.9 0.3 1.3 1 0 0 1 1 1 0 TraL protein DUF4690 PF15756.5 KIK68945.1 - 1.1 9.9 4.1 0.75 10.4 1.5 2.1 2 1 0 2 2 2 0 Small Novel Rich in Cartilage SARAF PF06682.12 KIK68945.1 - 1.2 8.7 5.7 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis AP_endonuc_2 PF01261.24 KIK68947.1 - 1.8e-30 106.0 0.0 3.1e-29 101.9 0.0 2.5 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel LysM PF01476.20 KIK68948.1 - 3.1e-24 84.8 0.0 2.7e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 LysM domain GRDB PF07355.12 KIK68948.1 - 0.007 15.7 0.1 0.21 10.8 0.0 2.0 2 0 0 2 2 2 2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) G-patch_2 PF12656.7 KIK68949.1 - 1.8e-23 82.4 0.1 7e-23 80.5 0.1 2.1 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 KIK68949.1 - 0.0015 18.4 0.3 0.0037 17.1 0.3 1.8 1 0 0 1 1 1 1 G-patch domain Fe-S_biosyn PF01521.20 KIK68950.1 - 1.5e-12 47.7 0.0 2.8e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis ATPgrasp_Ter PF15632.6 KIK68950.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Ras PF00071.22 KIK68952.1 - 1.6e-33 115.6 0.0 2.1e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK68952.1 - 7.4e-15 55.2 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Zn_clus PF00172.18 KIK68953.1 - 1.8e-05 24.8 6.6 5.1e-05 23.3 6.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4653 PF15546.6 KIK68953.1 - 0.16 11.5 0.7 0.29 10.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Mito_carr PF00153.27 KIK68954.1 - 5.8e-55 183.2 7.1 5e-21 74.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK68954.1 - 0.00026 20.2 0.1 0.0098 15.1 0.0 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease TBPIP PF07106.13 KIK68955.1 - 2e-16 59.7 0.1 3.8e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Lebercilin PF15619.6 KIK68955.1 - 5.7e-05 22.9 0.4 9.3e-05 22.2 0.4 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Phage_GP20 PF06810.11 KIK68955.1 - 0.00013 21.8 2.0 0.00031 20.6 2.0 1.6 1 0 0 1 1 1 1 Phage minor structural protein GP20 Leu_zip PF15294.6 KIK68955.1 - 0.0021 17.7 1.3 0.0031 17.1 1.3 1.3 1 0 0 1 1 1 1 Leucine zipper LRRFIP PF09738.9 KIK68955.1 - 0.0052 16.3 0.9 0.0078 15.7 0.9 1.3 1 0 0 1 1 1 1 LRRFIP family ZapB PF06005.12 KIK68955.1 - 0.0082 16.6 5.9 0.14 12.6 5.9 2.5 1 1 0 1 1 1 1 Cell division protein ZapB Penicillinase_R PF03965.16 KIK68955.1 - 0.0097 16.3 0.4 0.024 15.0 0.4 1.6 1 0 0 1 1 1 1 Penicillinase repressor bZIP_1 PF00170.21 KIK68955.1 - 0.019 15.1 4.1 0.041 14.0 2.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor z-alpha PF02295.17 KIK68955.1 - 0.022 14.8 0.1 0.056 13.5 0.1 1.7 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain FlxA PF14282.6 KIK68955.1 - 0.056 13.4 5.1 0.94 9.5 3.5 2.5 1 1 1 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 KIK68955.1 - 0.083 13.0 1.8 0.14 12.3 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 KIK68955.1 - 0.11 12.9 0.9 2.2 8.7 0.5 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 KIK68955.1 - 0.15 12.3 5.6 0.11 12.8 2.1 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Cob_adeno_trans PF01923.18 KIK68955.1 - 0.19 11.9 1.8 5 7.2 0.1 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Lzipper-MIP1 PF14389.6 KIK68955.1 - 0.22 11.8 2.9 8.4 6.8 3.0 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 KIK68955.1 - 2.6 8.6 7.8 9.3 6.8 6.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIK68955.1 - 4.3 7.2 10.2 0.3 10.9 1.6 3.1 3 1 1 4 4 4 0 Septum formation initiator TMF_DNA_bd PF12329.8 KIK68955.1 - 8.4 6.5 11.6 0.53 10.3 5.1 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Ank_4 PF13637.6 KIK68956.1 - 4.5e-17 62.2 0.4 4.2e-08 33.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK68956.1 - 9.8e-17 61.3 0.1 8.6e-08 32.7 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK68956.1 - 3.3e-16 58.9 1.5 9.2e-08 32.2 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK68956.1 - 6.7e-11 41.4 0.4 0.00013 22.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIK68956.1 - 9.1e-11 41.8 0.6 0.0021 18.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) GIT_SHD PF08518.11 KIK68957.1 - 6.7e-27 92.8 3.9 3.5e-14 52.1 0.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Gp58 PF07902.11 KIK68957.1 - 0.0057 15.0 4.5 0.011 14.0 4.5 1.4 1 0 0 1 1 1 1 gp58-like protein Golgin_A5 PF09787.9 KIK68957.1 - 0.61 9.5 33.4 1.8 7.9 21.6 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 ANAPC15 PF15243.6 KIK68957.1 - 2.5 8.5 8.4 12 6.3 7.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Lebercilin PF15619.6 KIK68957.1 - 4 7.1 34.1 0.83 9.3 1.4 3.6 4 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KIK68957.1 - 4.6 6.5 29.4 0.094 12.1 9.8 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Nsp1_C PF05064.13 KIK68957.1 - 5.7 6.8 12.8 0.8 9.5 6.0 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region SpecificRecomb PF10136.9 KIK68957.1 - 5.7 5.1 10.0 1.4 7.2 6.3 1.8 2 0 0 2 2 2 0 Site-specific recombinase Tropomyosin PF00261.20 KIK68957.1 - 9.4 5.5 35.0 27 4.0 35.0 1.8 1 1 0 1 1 1 0 Tropomyosin adh_short PF00106.25 KIK68958.1 - 1.2e-41 142.4 1.8 1.9e-41 141.7 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK68958.1 - 3.5e-25 88.9 0.8 4.7e-25 88.5 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK68958.1 - 0.00027 20.9 0.3 0.00051 20.0 0.3 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK68958.1 - 0.02 14.8 0.3 0.057 13.3 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KIK68958.1 - 0.072 12.4 0.0 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.27 KIK68958.1 - 0.074 13.6 0.1 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK68958.1 - 0.085 12.1 0.1 0.15 11.3 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GH3 PF03321.13 KIK68961.1 - 0.034 13.0 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter AAA PF00004.29 KIK68962.1 - 9.6e-55 184.6 0.0 4.1e-42 143.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KIK68962.1 - 1.3e-23 83.2 0.9 4.2e-23 81.6 0.4 2.2 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KIK68962.1 - 1.4e-12 47.2 1.5 1.6e-08 34.2 0.1 3.0 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KIK68962.1 - 1.8e-11 44.7 2.7 9.6e-05 22.8 0.0 4.3 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KIK68962.1 - 1.4e-07 31.9 3.3 0.023 15.0 0.0 5.0 3 2 2 5 5 5 2 AAA domain AAA_14 PF13173.6 KIK68962.1 - 1.8e-07 31.3 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KIK68962.1 - 6.2e-06 26.0 0.0 0.014 15.1 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KIK68962.1 - 1.2e-05 25.3 0.3 0.016 15.1 0.0 3.5 3 1 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 KIK68962.1 - 1.5e-05 25.6 0.0 0.21 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KIK68962.1 - 2.2e-05 23.8 0.0 0.007 15.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 KIK68962.1 - 3e-05 24.0 0.2 0.2 11.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIK68962.1 - 6.8e-05 22.7 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KIK68962.1 - 0.00013 21.9 0.0 0.54 10.3 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KIK68962.1 - 0.00015 21.6 0.0 0.59 9.8 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KIK68962.1 - 0.00018 22.0 1.2 0.25 11.9 0.0 4.0 4 0 0 4 4 4 1 ABC transporter Sigma54_activat PF00158.26 KIK68962.1 - 0.00022 21.0 0.0 0.034 13.8 0.0 3.1 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIK68962.1 - 0.00023 20.6 0.1 0.74 9.2 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KIK68962.1 - 0.0004 20.6 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 KIK68962.1 - 0.00049 20.1 0.4 0.14 12.1 0.1 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KIK68962.1 - 0.00059 20.2 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 KIK68962.1 - 0.00078 19.4 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Bac_DnaA PF00308.18 KIK68962.1 - 0.00081 19.3 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_29 PF13555.6 KIK68962.1 - 0.00093 18.9 0.1 0.024 14.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KIK68962.1 - 0.0013 18.9 0.1 0.073 13.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 KIK68962.1 - 0.0014 17.9 0.1 0.22 10.7 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain TniB PF05621.11 KIK68962.1 - 0.0019 17.6 0.0 0.29 10.5 0.0 3.5 3 1 1 4 4 3 1 Bacterial TniB protein AAA_7 PF12775.7 KIK68962.1 - 0.0024 17.4 0.1 0.3 10.6 0.1 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_3 PF07726.11 KIK68962.1 - 0.007 16.2 0.0 2.5 8.0 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIK68962.1 - 0.015 14.5 0.0 0.43 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) LPP20 PF02169.16 KIK68962.1 - 0.019 15.3 1.0 0.1 13.0 0.5 2.3 2 0 0 2 2 2 0 LPP20 lipoprotein AAA_30 PF13604.6 KIK68962.1 - 0.025 14.3 0.1 0.025 14.3 0.1 2.6 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KIK68962.1 - 0.028 14.0 2.3 1.7 8.1 0.2 3.6 2 2 2 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 KIK68962.1 - 0.034 13.8 0.0 0.51 10.0 0.0 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain HTH_37 PF13744.6 KIK68962.1 - 0.036 14.0 1.0 0.11 12.5 1.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain SHS2_FTSA PF02491.20 KIK68962.1 - 0.037 14.4 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Cytidylate_kin2 PF13189.6 KIK68962.1 - 0.052 13.7 0.1 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF2075 PF09848.9 KIK68962.1 - 0.062 12.5 0.1 8.7 5.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KIK68962.1 - 0.077 13.2 0.1 9.1 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK68962.1 - 0.08 13.3 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK68962.1 - 0.094 12.6 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KIK68962.1 - 0.24 10.7 0.7 14 4.9 0.0 3.0 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 KIK68962.1 - 0.8 8.9 5.1 4.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_17 PF13207.6 KIK68962.1 - 3 8.3 5.5 2.3 8.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain EBV-NA3 PF05009.12 KIK68964.1 - 0.21 11.1 1.2 0.42 10.1 1.2 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXLR PF16810.5 KIK68964.1 - 1.2 9.5 3.9 13 6.2 0.2 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity TPR_1 PF00515.28 KIK68965.1 - 5.4e-21 73.5 1.8 2.2e-06 27.2 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68965.1 - 1e-16 59.6 3.4 0.00056 19.8 0.0 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat ANAPC8 PF04049.13 KIK68965.1 - 7.4e-15 55.2 0.1 2.5e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KIK68965.1 - 1.8e-12 46.4 2.1 0.0032 17.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK68965.1 - 2.8e-11 42.9 0.0 0.00018 21.1 0.1 3.9 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 KIK68965.1 - 5.4e-10 39.2 6.0 0.32 11.9 0.0 7.0 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK68965.1 - 1e-08 35.3 1.3 0.0095 16.2 0.1 5.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK68965.1 - 6.2e-07 29.4 1.5 5 7.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK68965.1 - 1.4e-05 24.7 0.1 0.22 11.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK68965.1 - 2.4e-05 24.8 0.4 3 8.4 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK68965.1 - 0.00023 21.8 4.1 2.1 9.1 0.0 4.9 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK68965.1 - 0.00097 19.2 1.0 2.2 8.5 0.1 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat SNAP PF14938.6 KIK68965.1 - 0.016 14.6 0.5 0.21 11.0 0.5 2.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KIK68965.1 - 0.072 13.0 1.1 77 3.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 KIK68965.1 - 0.1 13.3 0.7 4.2 8.2 0.0 3.0 2 0 0 2 2 2 0 Sel1 repeat FA_desaturase PF00487.24 KIK68966.1 - 3.8e-29 102.3 20.7 5.1e-29 101.9 20.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK68966.1 - 1.7e-06 28.1 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glutaredoxin PF00462.24 KIK68967.1 - 7.6e-12 45.3 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KIK68967.1 - 0.011 16.2 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain GCP_N_terminal PF17681.1 KIK68968.1 - 1.8e-66 224.9 0.0 3.8e-66 223.8 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIK68968.1 - 3.2e-56 191.1 10.5 6.1e-56 190.1 7.4 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal HAD_2 PF13419.6 KIK68969.1 - 4.5e-19 69.2 0.0 1.1e-17 64.7 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK68969.1 - 4.3e-11 43.5 0.1 3e-10 40.8 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIK68969.1 - 0.0021 18.1 0.0 0.48 10.6 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK68969.1 - 0.058 13.5 0.1 0.42 10.7 0.0 2.4 3 0 0 3 3 3 0 HAD-hyrolase-like HAD PF12710.7 KIK68969.1 - 0.093 13.1 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK68970.1 - 6.1e-19 68.8 0.0 3.4e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK68970.1 - 7.9e-10 39.4 0.4 1.9e-08 34.9 0.4 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIK68970.1 - 0.0042 17.2 0.0 0.39 10.8 0.0 2.6 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK68971.1 - 2.4e-18 66.8 0.0 1.8e-17 64.0 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK68971.1 - 1.3e-08 35.4 0.0 8.8e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4538 PF15061.6 KIK68972.1 - 0.43 10.4 1.6 0.53 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF2828 PF11443.8 KIK68973.1 - 1.2e-225 750.4 0.2 1.4e-225 750.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FGE-sulfatase PF03781.16 KIK68974.1 - 1.6e-16 60.7 0.3 7.4e-15 55.2 0.3 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIK68974.1 - 5.5e-09 36.6 0.3 1.1e-08 35.6 0.3 1.5 1 0 0 1 1 1 1 DinB superfamily UPF0029 PF01205.19 KIK68978.1 - 2.4e-25 88.9 0.0 3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Glucosamine_iso PF01182.20 KIK68979.1 - 2.1e-20 73.6 0.0 4e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4532 PF15046.6 KIK68979.1 - 0.16 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Glyco_hydro_15 PF00723.21 KIK68980.1 - 1.4e-92 310.9 0.1 1.6e-92 310.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIK68980.1 - 1e-30 105.5 0.3 2.1e-30 104.5 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain AMPK1_CBM PF16561.5 KIK68980.1 - 0.029 14.6 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase CsoSCA PF08936.10 KIK68980.1 - 0.088 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Glyco_hydro_15 PF00723.21 KIK68981.1 - 2.3e-81 273.9 0.2 2.7e-81 273.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIK68981.1 - 4.7e-27 93.7 0.2 9.1e-27 92.8 0.2 1.5 1 0 0 1 1 1 1 Starch binding domain AMPK1_CBM PF16561.5 KIK68981.1 - 0.024 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase TMCO5 PF14992.6 KIK68984.1 - 0.041 13.5 0.3 0.047 13.3 0.3 1.0 1 0 0 1 1 1 0 TMCO5 family AMP-binding PF00501.28 KIK68985.1 - 1.5e-06 27.1 0.0 5.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF2407 PF10302.9 KIK68986.1 - 1.9e-18 66.9 0.2 3.1e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 KIK68986.1 - 2.1e-16 60.4 10.6 1.6e-15 57.5 4.1 3.2 3 1 0 3 3 3 2 DUF2407 C-terminal domain ubiquitin PF00240.23 KIK68986.1 - 1.3e-05 24.9 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_15 PF00723.21 KIK68987.1 - 3.7e-95 319.3 1.0 4.4e-95 319.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIK68987.1 - 1.1e-26 92.5 0.5 3.9e-26 90.8 0.0 2.1 2 0 0 2 2 2 1 Starch binding domain G-patch PF01585.23 KIK68988.1 - 2.3e-09 37.0 0.2 8.3e-09 35.2 0.2 2.1 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIK68988.1 - 0.0005 20.1 0.2 0.0005 20.1 0.2 4.7 5 1 0 5 5 5 1 G-patch domain DHquinase_I PF01487.15 KIK68989.1 - 3.1e-49 168.3 0.0 5.3e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KIK68989.1 - 8.2e-28 97.5 0.0 1.5e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 KIK68989.1 - 6.3e-24 84.0 0.0 1.3e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KIK68989.1 - 9.3e-10 38.1 0.0 2.9e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KIK68989.1 - 3.8e-07 30.2 0.0 7.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.6 KIK68989.1 - 0.0029 18.1 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK68989.1 - 0.0039 17.4 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK68989.1 - 0.017 15.1 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sacchrp_dh_NADP PF03435.18 KIK68989.1 - 0.038 14.3 0.9 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Abhydrolase_1 PF00561.20 KIK68990.1 - 1.1e-24 87.4 0.3 4.4e-24 85.5 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KIK68990.1 - 2.8e-22 78.1 0.0 6e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KIK68990.1 - 2.3e-05 23.8 0.0 0.0028 17.0 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KIK68990.1 - 0.0011 18.7 0.2 0.043 13.5 0.1 2.6 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.20 KIK68990.1 - 0.0056 16.3 0.1 0.0093 15.6 0.1 1.3 1 0 0 1 1 1 1 Putative esterase CPT_N PF16484.5 KIK68990.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.9 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Shikimate_dh_N PF08501.11 KIK68991.1 - 6.7e-22 77.6 0.0 1.4e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Pkinase PF00069.25 KIK68992.1 - 2.2e-67 227.2 0.0 2.8e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK68992.1 - 1.1e-29 103.5 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK68992.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK68992.1 - 0.022 14.7 0.1 0.16 11.9 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK68992.1 - 0.043 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2737 PF10930.8 KIK68992.1 - 0.15 11.7 0.3 5 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) Gly_transf_sug PF04488.15 KIK68993.1 - 4.2e-05 24.1 0.0 0.00021 21.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK68993.1 - 0.024 14.0 0.9 0.038 13.4 0.9 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein zf-C2H2 PF00096.26 KIK68994.1 - 4.4e-28 96.2 70.6 0.0011 19.3 2.8 10.7 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK68994.1 - 4.1e-19 67.6 64.1 0.0053 17.5 1.0 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK68994.1 - 7.8e-10 38.7 66.3 6.3e-06 26.4 0.9 11.9 12 0 0 12 12 12 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIK68994.1 - 7e-08 32.7 28.7 0.054 13.8 5.2 5.6 1 1 4 5 5 5 4 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIK68994.1 - 0.00051 20.6 32.8 0.57 10.9 0.6 8.2 5 3 4 9 9 9 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KIK68994.1 - 0.0036 17.5 27.5 0.17 12.2 0.7 7.8 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK68994.1 - 0.0036 17.3 38.1 0.22 11.6 1.5 8.9 10 0 0 10 10 10 4 C2H2-type zinc finger zf-met PF12874.7 KIK68994.1 - 0.012 16.0 1.9 0.012 16.0 1.9 6.4 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KIK68994.1 - 0.21 11.7 26.8 5.1 7.2 3.5 5.7 5 2 0 5 5 5 0 Aberrant zinc-finger PhoLip_ATPase_C PF16212.5 KIK68995.1 - 2e-81 273.4 25.5 2e-81 273.4 25.5 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK68995.1 - 1.1e-24 85.8 6.7 3.4e-24 84.3 6.7 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIK68995.1 - 5.2e-12 46.5 2.3 1.4e-07 32.0 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK68995.1 - 7e-12 45.3 0.0 2.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIK68995.1 - 1.2e-09 37.9 0.0 3.3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIK68995.1 - 0.0021 17.8 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 KIK68995.1 - 0.02 15.2 0.1 0.078 13.2 0.1 2.0 1 0 0 1 1 1 0 DNA polymerase III psi subunit PB1 PF00564.24 KIK68996.1 - 6.6e-14 51.6 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 KIK68996.1 - 8.8e-09 34.8 4.8 0.03 14.1 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK68996.1 - 1.5e-08 34.1 3.6 0.39 10.9 0.6 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK68996.1 - 7.1e-07 29.4 1.1 0.00019 21.7 0.3 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK68996.1 - 1.8e-06 27.7 2.3 0.026 14.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK68996.1 - 0.0065 16.1 1.3 0.013 15.2 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KIK68996.1 - 0.0085 16.1 0.4 0.6 10.3 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK68996.1 - 0.15 11.9 1.6 2.8 8.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HA2 PF04408.23 KIK68997.1 - 3.6e-22 78.7 0.0 3.6e-22 78.7 0.0 3.3 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK68997.1 - 2e-12 47.5 0.0 4.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK68997.1 - 6.2e-09 35.9 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KIK68997.1 - 1.2e-08 35.2 0.0 2.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KIK68997.1 - 6.2e-06 26.5 0.4 2.1e-05 24.8 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK68997.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK68997.1 - 0.00044 19.6 0.0 0.0008 18.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIK68997.1 - 0.0011 19.4 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK68997.1 - 0.0018 17.4 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KIK68997.1 - 0.013 15.5 0.0 7.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KIK68997.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KIK68997.1 - 0.025 15.1 0.0 0.11 13.1 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KIK68997.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK68997.1 - 0.032 14.0 0.0 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 KIK68997.1 - 0.04 14.0 0.1 0.25 11.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIK68997.1 - 0.042 13.5 0.1 0.12 12.0 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 KIK68997.1 - 0.096 12.1 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KIK68997.1 - 0.099 12.8 0.0 0.46 10.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK68997.1 - 0.17 11.8 0.1 0.72 9.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF1744 PF08490.12 KIK68999.1 - 1.6e-131 438.6 0.0 2.5e-131 437.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KIK68999.1 - 4.1e-73 246.4 0.1 6.3e-73 245.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KIK68999.1 - 1.1e-11 44.1 1.8 3e-05 22.9 0.0 4.4 4 1 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KIK68999.1 - 2.5e-08 33.9 0.1 6.3e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KIK68999.1 - 8.2e-05 22.7 0.1 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 RNase_H superfamily Toxin_28 PF08115.11 KIK68999.1 - 0.025 14.5 0.2 0.062 13.2 0.2 1.7 1 0 0 1 1 1 0 SFI toxin family DUF3716 PF12511.8 KIK68999.1 - 6.1 7.0 9.7 5.8 7.1 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) zf-H2C2_2 PF13465.6 KIK69000.1 - 6.1e-10 39.1 4.3 7.1e-08 32.5 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK69000.1 - 4.1e-08 33.2 10.9 3.2e-06 27.3 0.3 3.8 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIK69000.1 - 2.9e-07 31.0 5.0 0.017 15.7 2.1 3.1 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIK69000.1 - 0.0037 17.2 1.4 0.064 13.3 0.1 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KIK69000.1 - 0.0057 17.4 10.1 0.012 16.4 0.3 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KIK69000.1 - 0.017 15.5 1.3 5.2 7.6 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KIK69000.1 - 0.041 14.2 3.9 0.64 10.4 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KIK69000.1 - 0.042 14.2 1.2 0.1 12.9 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon DOPA_dioxygen PF08883.11 KIK69001.1 - 1.7e-27 95.7 0.0 2.2e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family JmjC PF02373.22 KIK69002.1 - 2.2e-37 128.0 0.1 4.8e-37 126.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KIK69002.1 - 2.8e-14 52.8 0.8 5.6e-14 51.8 0.8 1.5 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KIK69002.1 - 3.8e-14 52.7 1.6 1.1e-13 51.2 1.6 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIK69002.1 - 7.4e-12 45.4 1.6 7.4e-12 45.4 1.6 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 KIK69002.1 - 0.0092 15.9 2.3 0.0092 15.9 2.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-C2H2_4 PF13894.6 KIK69003.1 - 1.7e-05 25.2 21.2 0.042 14.7 0.4 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK69003.1 - 0.0013 19.1 29.1 0.01 16.3 0.3 4.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK69003.1 - 0.061 13.6 6.5 0.076 13.3 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KIK69003.1 - 0.21 11.4 4.2 3.8 7.4 0.6 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KIK69003.1 - 1.6 9.3 6.3 3.5 8.2 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type IGPS PF00218.21 KIK69004.1 - 7.2e-87 290.7 0.0 1.3e-86 290.0 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KIK69004.1 - 2.2e-43 148.3 0.0 4.4e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KIK69004.1 - 5.9e-39 133.9 0.0 5.4e-20 72.0 0.0 3.5 2 1 1 3 3 3 3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KIK69004.1 - 5.4e-06 26.3 0.2 1.5e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KIK69004.1 - 0.00055 19.8 1.0 0.0017 18.1 0.1 2.2 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain DHO_dh PF01180.21 KIK69004.1 - 0.0079 15.4 0.1 4.6 6.4 0.1 3.1 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase Peptidase_S10 PF00450.22 KIK69005.1 - 3.9e-66 224.2 2.1 1.9e-65 221.9 2.1 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase HtrL_YibB PF09612.10 KIK69006.1 - 0.0071 15.9 0.0 0.016 14.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) SQHop_cyclase_N PF13249.6 KIK69007.1 - 7.5e-48 163.1 0.0 1.8e-40 138.9 0.0 3.7 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIK69007.1 - 5.5e-47 160.4 2.2 2.6e-44 151.6 0.7 2.6 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KIK69007.1 - 8.9e-36 121.3 7.2 8.9e-12 44.5 0.8 6.4 7 0 0 7 7 7 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KIK69007.1 - 0.00056 19.3 0.2 0.61 9.4 0.0 3.6 2 1 1 4 4 4 2 Pectic acid lyase ER_lumen_recept PF00810.18 KIK69008.1 - 1e-56 191.8 8.6 1.6e-56 191.2 8.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KIK69008.1 - 9.7e-05 22.1 9.6 0.051 13.4 0.3 4.2 4 0 0 4 4 4 2 PQ loop repeat DUF4203 PF13886.6 KIK69009.1 - 6.6e-18 65.1 25.9 1e-17 64.5 25.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DnaJ PF00226.31 KIK69010.1 - 7.7e-11 42.0 0.0 2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain RRM_7 PF16367.5 KIK69010.1 - 0.15 12.2 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Rit1_C PF17184.4 KIK69011.1 - 5.5e-93 311.3 0.0 7.7e-93 310.9 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KIK69011.1 - 1.8e-12 47.5 0.0 4.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain Calpain_III PF01067.22 KIK69012.1 - 3.9e-17 62.8 0.7 1.8e-08 34.8 0.3 3.6 2 2 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KIK69012.1 - 7.7e-12 44.8 0.0 3.7e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 KIK69012.1 - 5.7e-08 32.7 1.0 9.9e-08 31.9 1.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain V-set PF07686.17 KIK69012.1 - 0.044 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin V-set domain USP8_dimer PF08969.11 KIK69012.1 - 0.55 10.4 2.4 12 6.2 0.3 2.3 1 1 1 2 2 2 0 USP8 dimerisation domain Glyco_hydro_71 PF03659.14 KIK69013.1 - 3.3e-104 348.7 0.2 3.7e-104 348.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SnoaL_2 PF12680.7 KIK69015.1 - 0.0012 19.4 0.0 0.0017 19.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain RRM_Rrp7 PF17799.1 KIK69015.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DUF3483 PF11982.8 KIK69015.1 - 0.2 11.2 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) Kri1 PF05178.12 KIK69016.1 - 8.2e-26 90.6 8.8 8.2e-26 90.6 8.8 5.8 4 3 1 5 5 5 1 KRI1-like family Kri1_C PF12936.7 KIK69016.1 - 7.8e-25 86.9 0.1 7.8e-25 86.9 0.1 4.6 5 0 0 5 5 5 1 KRI1-like family C-terminal WD40 PF00400.32 KIK69017.1 - 2.5e-21 75.5 21.1 5.9e-05 23.8 0.9 7.4 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK69017.1 - 1.5e-07 31.6 5.7 0.071 13.4 0.1 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK69017.1 - 7.2e-06 25.2 0.2 0.048 12.6 0.1 3.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GTP_EFTU PF00009.27 KIK69018.1 - 9.5e-60 201.5 0.0 1.5e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIK69018.1 - 4.9e-37 126.4 0.1 2.5e-36 124.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KIK69018.1 - 3.7e-30 103.8 0.0 7.8e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KIK69018.1 - 5.6e-22 77.6 0.0 1.5e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK69018.1 - 2.6e-13 50.2 0.0 6.9e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KIK69018.1 - 3.5e-07 30.1 0.0 6.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KIK69019.1 - 2.3e-19 69.6 0.3 1.1e-15 57.7 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK69019.1 - 3e-08 33.7 0.0 1.7e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KIK69019.1 - 4.8e-08 32.7 0.0 3.8e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIK69019.1 - 0.00016 21.7 0.5 0.24 11.4 0.1 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KIK69019.1 - 0.00059 19.4 0.0 0.028 14.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK69019.1 - 0.008 16.4 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK69019.1 - 0.0084 16.5 0.5 0.6 10.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KIK69019.1 - 0.037 14.6 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KIK69019.1 - 0.037 13.0 0.0 0.08 11.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KIK69019.1 - 0.056 12.8 0.2 0.37 10.1 0.1 2.1 2 0 0 2 2 2 0 AIG1 family THF_DHG_CYH_C PF02882.19 KIK69019.1 - 0.072 12.4 0.5 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain cobW PF02492.19 KIK69019.1 - 0.15 11.7 0.0 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-C3HC PF07967.13 KIK69020.1 - 0.012 15.6 0.3 0.093 12.8 0.0 2.0 1 1 0 2 2 2 0 C3HC zinc finger-like Med9 PF07544.13 KIK69023.1 - 5.1 7.3 15.8 0.03 14.4 4.2 3.3 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 KIK69023.1 - 8.8 6.4 8.9 13 5.9 2.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 KIK69024.1 - 4.1e-14 52.3 53.7 1e-06 28.0 38.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspanin PF00335.20 KIK69025.1 - 2.2e-11 43.9 8.4 3.5e-11 43.3 8.4 1.3 1 0 0 1 1 1 1 Tetraspanin family Mrr_N PF14338.6 KIK69025.1 - 0.17 12.0 0.2 0.33 11.1 0.2 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain UPF0203 PF05254.12 KIK69026.1 - 5.7e-26 90.6 4.5 8.3e-26 90.0 4.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KIK69026.1 - 0.0058 16.8 3.6 1.5 9.1 1.0 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 KIK69026.1 - 0.0075 16.6 1.0 2 8.8 0.3 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Glyco_hydro_99 PF16317.5 KIK69026.1 - 0.016 14.4 0.4 0.019 14.1 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 Nucleolin_bd PF16725.5 KIK69026.1 - 0.023 14.4 0.1 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 Nucleolin binding domain CHCH PF06747.13 KIK69026.1 - 0.081 13.1 3.9 0.25 11.5 0.8 2.3 2 0 0 2 2 2 0 CHCH domain RNB PF00773.19 KIK69027.1 - 3e-95 319.3 0.0 4.3e-95 318.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KIK69027.1 - 2.8e-25 88.8 0.8 5.6e-25 87.8 0.1 1.9 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KIK69027.1 - 2.3e-23 82.0 4.6 5.5e-23 80.7 4.6 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KIK69027.1 - 2.2e-15 56.4 0.1 8.2e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KIK69027.1 - 2.9e-09 37.3 0.0 6.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KIK69027.1 - 3.6e-08 33.5 4.9 0.0037 17.4 0.0 5.0 5 0 0 5 5 5 3 Cold shock domain OB_RNB PF08206.11 KIK69027.1 - 0.0052 16.4 2.8 0.047 13.4 0.1 2.9 2 0 0 2 2 2 1 Ribonuclease B OB domain FMN_dh PF01070.18 KIK69028.1 - 9e-114 380.1 0.0 1.1e-113 379.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK69028.1 - 2.7e-20 72.3 0.0 5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIK69028.1 - 1.4e-05 24.5 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIK69028.1 - 0.00024 20.2 3.0 0.0012 17.9 0.5 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KIK69028.1 - 0.0035 16.8 0.1 0.0074 15.7 0.0 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase Peptidase_C7 PF01830.18 KIK69029.1 - 0.02 14.3 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Peptidase C7 family Lectin_leg-like PF03388.13 KIK69030.1 - 4.2e-63 212.8 0.1 5.1e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KIK69030.1 - 0.0026 17.3 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain Arb1 PF09692.10 KIK69031.1 - 2e-07 30.6 0.0 6.7e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 eRF1_1 PF03463.15 KIK69033.1 - 0.01 15.8 0.0 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 eRF1 domain 1 HEAT_EZ PF13513.6 KIK69034.1 - 6.7e-25 87.2 16.3 6.3e-15 55.3 0.0 9.2 9 2 2 11 11 11 4 HEAT-like repeat HEAT PF02985.22 KIK69034.1 - 3.9e-16 57.8 13.8 0.0008 19.5 0.0 8.7 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 KIK69034.1 - 4.3e-13 49.5 0.2 0.00054 20.3 0.0 6.6 6 2 3 9 9 9 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KIK69034.1 - 7.6e-09 36.1 0.0 0.029 15.0 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region DUF3437 PF11919.8 KIK69034.1 - 4.5e-07 29.7 0.4 0.0096 15.8 0.0 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF3437) Cnd1 PF12717.7 KIK69034.1 - 3.4e-06 27.2 0.2 0.37 10.8 0.0 4.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 KIK69034.1 - 0.00067 19.3 0.2 1.5 8.3 0.0 4.1 2 2 1 3 3 3 2 Tti2 family IBN_N PF03810.19 KIK69034.1 - 0.00085 19.2 0.0 0.0037 17.2 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Arm PF00514.23 KIK69034.1 - 0.00087 19.2 0.1 4.5 7.5 0.0 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 KIK69034.1 - 0.022 15.1 1.6 14 6.1 0.2 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion MFS_1 PF07690.16 KIK69035.1 - 3.5e-20 72.2 43.5 3.5e-20 72.2 43.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KIK69036.1 - 4.4e-64 212.4 2.7 2e-22 78.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Homeodomain PF00046.29 KIK69037.1 - 0.00059 19.6 0.1 0.081 12.8 0.1 3.2 3 0 0 3 3 3 2 Homeodomain Homeodomain PF00046.29 KIK69038.1 - 0.00091 19.0 0.2 0.0021 17.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain SNF2_N PF00176.23 KIK69039.1 - 1.4e-64 218.1 0.1 2.2e-64 217.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK69039.1 - 4.7e-17 62.3 0.0 1.5e-15 57.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK69039.1 - 1.7e-08 34.7 0.0 3.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK69039.1 - 0.00024 20.9 0.0 0.00087 19.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KIK69039.1 - 0.0097 15.9 0.1 0.38 10.7 0.0 2.4 2 0 0 2 2 2 1 Flavivirus DEAD domain HemY_N PF07219.13 KIK69039.1 - 1.5 9.1 5.9 2 8.7 3.3 2.3 2 0 0 2 2 2 0 HemY protein N-terminus HSA PF07529.13 KIK69039.1 - 7 7.1 15.6 8.8 6.7 5.6 3.6 3 0 0 3 3 3 0 HSA Pkinase PF00069.25 KIK69040.1 - 3.8e-70 236.3 0.0 4.5e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69040.1 - 1.5e-35 122.8 0.0 1.9e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK69040.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK69040.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family COX14 PF14880.6 KIK69041.1 - 2.1e-06 27.5 0.3 3.3e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly FR47 PF08445.10 KIK69042.1 - 4.5e-11 42.6 0.0 7.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KIK69042.1 - 4.9e-10 39.7 0.0 7.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KIK69042.1 - 3.1e-07 31.2 0.0 5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK69042.1 - 1.9e-06 27.8 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK69042.1 - 5.5e-06 26.7 0.0 9.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK69042.1 - 0.00012 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK69042.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KIK69042.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 KIK69042.1 - 0.026 14.6 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIK69042.1 - 0.036 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Clathrin PF00637.20 KIK69043.1 - 1.1e-17 64.2 0.0 1.3e-11 44.5 0.2 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KIK69043.1 - 6.8e-10 39.0 0.5 1.3e-09 38.1 0.5 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KIK69043.1 - 1e-08 35.1 8.2 1.7e-08 34.3 8.2 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KIK69043.1 - 0.019 14.8 8.1 0.033 14.0 8.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK69043.1 - 0.17 12.3 7.9 0.29 11.5 7.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KIK69043.1 - 1 9.4 7.1 1.7 8.7 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK69043.1 - 6.5 6.9 7.0 13 5.9 7.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger ATP-synt_J PF04911.12 KIK69044.1 - 1.5e-20 72.5 0.9 1.6e-20 72.4 0.9 1.0 1 0 0 1 1 1 1 ATP synthase j chain Oxidored_molyb PF00174.19 KIK69045.1 - 6.5e-47 159.3 0.0 1.5e-46 158.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIK69045.1 - 1.2e-17 64.2 2.0 2.1e-17 63.4 2.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain HCBP_related PF06594.11 KIK69045.1 - 0.22 11.5 0.7 0.93 9.5 0.3 2.0 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Peptidase_S8 PF00082.22 KIK69046.1 - 4e-35 121.5 9.7 6.2e-35 120.9 9.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIK69046.1 - 6.5e-08 33.1 0.1 1.8e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 Glyco_transf_49 PF13896.6 KIK69047.1 - 8.5e-59 199.5 0.3 1.1e-49 169.6 0.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan 2-Hacid_dh_C PF02826.19 KIK69048.1 - 6.1e-47 159.3 0.0 8e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK69048.1 - 2.2e-18 66.2 0.0 2.4e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK69048.1 - 0.0015 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Nop25 PF09805.9 KIK69048.1 - 0.17 12.4 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Propep_M14 PF02244.16 KIK69049.1 - 0.03 14.7 0.1 0.2 12.1 0.0 2.4 2 1 1 3 3 3 0 Carboxypeptidase activation peptide CdiI_2 PF18593.1 KIK69049.1 - 0.069 13.8 0.6 1.2 9.8 0.1 2.7 2 1 1 3 3 3 0 CdiI immunity protein DUF3526 PF12040.8 KIK69049.1 - 1.9 9.0 5.5 9.6 6.7 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3526) ADC PF06314.11 KIK69050.1 - 1.2e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Aldo_ket_red PF00248.21 KIK69052.1 - 8.8e-69 231.9 0.0 9.9e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 KIK69052.1 - 0.11 12.7 0.0 9.5 6.5 0.0 2.5 2 0 0 2 2 2 0 NAF domain zf-C2H2 PF00096.26 KIK69053.1 - 0.00048 20.4 6.4 0.015 15.8 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK69053.1 - 0.025 15.4 6.5 0.084 13.8 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KIK69053.1 - 0.027 14.5 2.2 0.082 12.9 2.2 1.9 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 KIK69053.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger SWIB PF02201.18 KIK69054.1 - 1.7e-28 98.3 0.1 2.8e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KIK69054.1 - 0.022 14.7 1.8 0.051 13.5 0.4 2.3 2 1 0 2 2 2 0 DEK C terminal domain GREB1 PF15782.5 KIK69054.1 - 0.24 8.5 2.0 0.29 8.2 2.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 KIK69054.1 - 4.7 5.9 8.2 5.7 5.6 8.2 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 KIK69054.1 - 7.7 6.4 17.8 10 5.9 17.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sel1 PF08238.12 KIK69055.1 - 2.5e-26 91.5 33.6 4.2e-05 24.1 0.3 9.4 9 1 0 9 9 9 7 Sel1 repeat DUF1180 PF06679.12 KIK69055.1 - 0.24 11.8 1.1 0.86 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TPR_2 PF07719.17 KIK69055.1 - 1.2 9.5 0.0 1.2 9.5 0.0 8.4 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK69055.1 - 5.6 7.6 6.0 50 4.6 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PPTA PF01239.22 KIK69056.1 - 7.8e-06 25.4 4.7 0.34 10.7 0.7 4.7 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat DUF810 PF05664.11 KIK69056.1 - 0.05 12.1 0.1 0.064 11.8 0.1 1.1 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) RNase_T PF00929.24 KIK69057.1 - 5.6e-33 114.8 0.0 6.6e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KIK69057.1 - 0.00026 21.0 0.2 0.00034 20.6 0.2 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like CPSase_L_D2 PF02786.17 KIK69059.1 - 5.8e-107 356.0 0.0 1.1e-82 276.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KIK69059.1 - 5.2e-41 139.8 0.9 1.3e-40 138.5 0.9 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KIK69059.1 - 2.5e-16 59.7 0.0 3.4e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIK69059.1 - 2.1e-11 43.8 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIK69059.1 - 9.6e-11 41.5 0.0 0.00025 20.8 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KIK69059.1 - 6.6e-06 25.7 0.1 0.008 15.7 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KIK69059.1 - 0.00069 19.7 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KIK69059.1 - 0.0038 16.9 0.0 1.7 8.2 0.0 2.8 3 0 0 3 3 3 2 RimK-like ATP-grasp domain MGS PF02142.22 KIK69059.1 - 0.011 15.9 0.0 0.053 13.7 0.0 2.3 2 0 0 2 2 2 0 MGS-like domain Peptidase_M17_N PF02789.17 KIK69059.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.24 KIK69060.1 - 2.4e-45 155.7 0.0 2.7e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK69060.1 - 2e-06 27.3 0.1 0.0085 15.3 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK69060.1 - 9.7e-05 22.4 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KIK69060.1 - 0.00011 22.7 0.0 0.008 16.7 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK69060.1 - 0.00013 22.2 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK69060.1 - 0.00077 18.9 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Sacchrp_dh_NADP PF03435.18 KIK69060.1 - 0.00095 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 KIK69060.1 - 0.0015 17.7 0.0 0.21 10.6 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.18 KIK69060.1 - 0.0032 17.7 0.0 0.0079 16.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain K_oxygenase PF13434.6 KIK69060.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KIK69060.1 - 0.024 13.9 0.0 0.066 12.4 0.0 1.8 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 KIK69060.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIK69060.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIK69060.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 KIK69060.1 - 0.059 12.6 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KIK69060.1 - 0.064 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 KIK69060.1 - 0.075 11.9 0.0 5.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KIK69060.1 - 0.13 10.9 0.0 6.1 5.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK69060.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lyase_aromatic PF00221.19 KIK69061.1 - 7.9e-151 502.8 1.6 1.1e-150 502.4 1.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase AAA_lid_5 PF17865.1 KIK69061.1 - 0.058 13.5 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain zf-C2H2_4 PF13894.6 KIK69062.1 - 9.1e-05 23.0 1.1 0.12 13.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK69062.1 - 0.00081 19.7 7.2 0.011 16.1 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK69062.1 - 0.041 14.2 0.2 3.2 8.1 0.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Fcf1 PF04900.12 KIK69063.1 - 3.2e-38 130.1 2.7 5.2e-38 129.4 2.7 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KIK69063.1 - 5.6e-12 46.0 0.1 2.2e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 PIN like domain zf-LYAR PF08790.11 KIK69064.1 - 2.4e-14 52.9 3.1 6.1e-14 51.6 3.1 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KIK69064.1 - 0.014 15.6 0.1 0.014 15.6 0.1 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KIK69064.1 - 0.062 12.9 1.0 0.75 9.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2367 PF10164.9 KIK69065.1 - 8.3e-09 35.9 0.7 1.5e-08 35.1 0.6 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Methyltransf_25 PF13649.6 KIK69066.1 - 2.9e-15 56.8 0.0 5.9e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69066.1 - 4.6e-13 49.2 0.0 1e-12 48.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK69066.1 - 2.3e-12 47.4 0.0 4.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK69066.1 - 9.4e-12 44.9 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KIK69066.1 - 1.7e-08 35.1 0.0 3.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK69066.1 - 3.2e-08 33.6 0.0 1.7e-07 31.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KIK69066.1 - 4.8e-08 32.6 0.0 7.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KIK69066.1 - 1.3e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KIK69066.1 - 4.4e-06 26.4 0.1 7.7e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIK69066.1 - 5.3e-06 25.9 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KIK69066.1 - 0.00018 21.0 0.2 0.00053 19.4 0.2 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KIK69066.1 - 0.00028 20.9 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIK69066.1 - 0.00031 20.7 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK69066.1 - 0.00038 19.8 0.0 0.00075 18.8 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 KIK69066.1 - 0.00091 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KIK69066.1 - 0.0011 18.8 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KIK69066.1 - 0.0049 17.0 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KIK69066.1 - 0.017 16.2 0.0 0.034 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KIK69066.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 KIK69066.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase LRR_2 PF07723.13 KIK69067.1 - 0.015 15.9 0.3 13 6.6 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat Tyrosinase PF00264.20 KIK69068.1 - 1.2e-34 120.6 0.9 1.6e-34 120.2 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase bZIP_1 PF00170.21 KIK69070.1 - 1e-10 41.5 11.0 1.2e-09 38.1 7.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIK69070.1 - 2.6e-10 40.2 17.9 1.2e-09 38.1 11.6 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KIK69070.1 - 0.003 18.0 4.1 0.003 18.0 4.1 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor TSC22 PF01166.18 KIK69070.1 - 0.015 15.6 0.6 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family HAP1_N PF04849.13 KIK69070.1 - 0.071 12.3 3.6 0.034 13.4 1.2 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF724 PF05266.14 KIK69070.1 - 0.071 12.9 0.7 0.1 12.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nnf1 PF03980.14 KIK69070.1 - 0.15 12.4 2.8 2.1 8.7 1.4 2.3 2 0 0 2 2 2 0 Nnf1 Csm1_N PF18504.1 KIK69070.1 - 0.42 11.0 2.2 7.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF5384 PF17358.2 KIK69070.1 - 7.5 6.6 13.6 0.23 11.5 7.7 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5384) DivIC PF04977.15 KIK69070.1 - 9.1 6.1 5.9 28 4.6 1.1 2.3 2 0 0 2 2 2 0 Septum formation initiator GMC_oxred_N PF00732.19 KIK69071.1 - 1.4e-55 188.8 0.0 1.9e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK69071.1 - 2e-33 115.9 0.0 3.7e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK69071.1 - 1.7e-05 24.9 0.0 0.00011 22.3 0.0 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK69071.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK69071.1 - 0.0004 19.6 0.0 0.0015 17.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK69071.1 - 0.0007 19.3 0.2 0.0037 16.9 0.0 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK69071.1 - 0.0008 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KIK69071.1 - 0.003 16.3 0.0 0.019 13.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIK69071.1 - 0.0032 16.7 0.0 0.0094 15.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK69071.1 - 0.016 14.5 0.0 0.059 12.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIK69071.1 - 0.071 13.4 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain LysM PF01476.20 KIK69073.1 - 3.7e-21 74.9 0.1 4.5e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 LysM domain YchF-GTPase_C PF06071.13 KIK69073.1 - 0.05 13.8 0.0 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF933) MCM_bind PF09739.9 KIK69074.1 - 5.5e-54 183.6 0.0 2.6e-45 155.0 0.0 3.7 1 1 2 3 3 3 3 Mini-chromosome maintenance replisome factor F-box-like PF12937.7 KIK69075.1 - 1.8e-12 46.9 1.7 6.9e-10 38.7 0.9 3.1 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KIK69075.1 - 0.015 15.2 0.9 0.015 15.2 0.9 2.6 2 1 0 2 2 2 0 F-box domain LRR_5 PF13306.6 KIK69075.1 - 0.21 11.5 3.6 0.16 11.9 1.3 2.0 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Glyco_hydro_cc PF11790.8 KIK69077.1 - 1.3e-71 241.0 2.8 1.6e-71 240.7 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans PF04082.18 KIK69078.1 - 5.5e-24 84.6 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KIK69078.1 - 0.083 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain AAA_lid_2 PF17863.1 KIK69079.1 - 0.0043 16.9 1.0 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 AAA lid domain ATP-synt_C PF00137.21 KIK69080.1 - 0.14 12.6 1.7 0.31 11.4 1.7 1.6 1 0 0 1 1 1 0 ATP synthase subunit C CD34_antigen PF06365.12 KIK69080.1 - 0.17 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family WBS28 PF15164.6 KIK69080.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Tudor_3 PF18115.1 KIK69080.1 - 0.2 11.5 0.1 27 4.7 0.1 2.5 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Vps53_N PF04100.12 KIK69081.1 - 2.1e-83 280.4 3.2 2.1e-83 280.4 3.2 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal RINT1_TIP1 PF04437.13 KIK69081.1 - 1.1e-05 24.6 0.6 1.1e-05 24.6 0.6 2.3 2 0 0 2 2 2 1 RINT-1 / TIP-1 family VPS53_C PF16854.5 KIK69081.1 - 1.8e-05 24.8 6.1 3.4e-05 23.8 0.0 3.5 3 1 1 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus DUF2451 PF10474.9 KIK69081.1 - 0.00021 21.2 0.7 0.00021 21.2 0.7 2.4 3 1 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KIK69081.1 - 0.0036 16.6 9.0 0.02 14.2 9.0 2.1 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF4533 PF15047.6 KIK69081.1 - 0.052 13.1 7.5 0.17 11.5 7.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF1664 PF07889.12 KIK69081.1 - 0.18 11.8 6.4 0.2 11.7 2.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 KIK69081.1 - 0.43 10.2 6.7 0.29 10.7 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3510 PF12022.8 KIK69081.1 - 1.3 9.4 5.8 2 8.8 0.1 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF3510) RRP36 PF06102.12 KIK69081.1 - 3.5 7.6 9.5 0.53 10.2 4.9 1.9 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 G_glu_transpept PF01019.21 KIK69082.1 - 8.7e-153 509.8 0.1 9.9e-153 509.6 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Yippee-Mis18 PF03226.14 KIK69083.1 - 1.7e-15 57.1 0.0 2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Phage_tail_APC PF16778.5 KIK69084.1 - 0.076 12.9 0.6 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 Phage tail assembly chaperone protein DSPn PF14671.6 KIK69085.1 - 0.027 14.9 0.2 0.033 14.6 0.2 1.1 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Oxidored_FMN PF00724.20 KIK69086.1 - 6.7e-94 314.9 0.0 1.9e-93 313.5 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rpr2 PF04032.16 KIK69088.1 - 8.5e-22 77.2 2.3 8.5e-22 77.2 2.3 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 KIK69088.1 - 0.047 13.8 0.7 0.078 13.1 0.7 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain DZR PF12773.7 KIK69088.1 - 0.1 12.6 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Rsbr_N PF08678.10 KIK69090.1 - 0.17 12.0 0.0 0.72 9.9 0.0 2.0 2 0 0 2 2 2 0 Rsbr N terminal Abhydrolase_6 PF12697.7 KIK69091.1 - 4.4e-13 50.4 0.0 7.8e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Exo_endo_phos PF03372.23 KIK69092.1 - 2e-17 63.5 0.2 2.5e-08 33.7 0.0 2.5 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KIK69092.1 - 2.2e-12 46.6 3.5 2.5e-09 36.8 2.4 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIK69092.1 - 2.6e-10 40.4 9.6 1.2e-06 28.8 2.1 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK69092.1 - 1.7 9.5 13.1 0.66 10.7 0.4 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Kdo PF06293.14 KIK69093.1 - 0.0018 17.7 0.2 0.018 14.4 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family LysM PF01476.20 KIK69094.1 - 9.5e-40 134.4 0.0 4.2e-12 45.9 0.0 3.1 3 0 0 3 3 3 3 LysM domain DAZAP2 PF11029.8 KIK69094.1 - 0.003 18.5 1.4 0.38 11.7 0.2 2.4 2 0 0 2 2 2 2 DAZ associated protein 2 (DAZAP2) TIL PF01826.17 KIK69094.1 - 0.05 13.9 7.0 4.5 7.6 0.1 3.6 4 0 0 4 4 4 0 Trypsin Inhibitor like cysteine rich domain HTH_28 PF13518.6 KIK69094.1 - 0.16 12.2 0.0 37 4.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Metallothio PF00131.20 KIK69094.1 - 9.3 6.5 10.3 37 4.5 0.8 3.3 1 1 2 3 3 3 0 Metallothionein bZIP_1 PF00170.21 KIK69095.1 - 3.4e-09 36.7 6.9 3.5e-09 36.6 1.4 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIK69095.1 - 5.3e-08 32.8 11.8 6.4e-08 32.6 3.7 2.2 2 0 0 2 2 2 2 Basic region leucine zipper MRVI1 PF05781.12 KIK69095.1 - 0.0032 16.2 1.4 0.0059 15.4 1.4 1.4 1 0 0 1 1 1 1 MRVI1 protein bZIP_Maf PF03131.17 KIK69095.1 - 0.0036 17.8 2.0 0.0036 17.8 2.0 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor LegC3_N PF18654.1 KIK69095.1 - 0.0041 16.4 0.1 1.3 8.2 0.1 2.1 1 1 1 2 2 2 2 LegC3 N-terminal coiled-coil domain CCDC106 PF15794.5 KIK69095.1 - 0.0094 15.7 0.8 0.015 15.0 0.2 1.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 106 WD40_alt PF14077.6 KIK69095.1 - 0.012 15.4 0.2 0.026 14.4 0.2 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Miga PF10265.9 KIK69095.1 - 0.29 10.1 2.7 0.31 10.0 2.7 1.1 1 0 0 1 1 1 0 Mitoguardin HNH_repeat PF18780.1 KIK69096.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Homing endonuclease repeat CHZ PF09649.10 KIK69097.1 - 1.4e-10 40.4 0.2 1.4e-10 40.4 0.2 2.5 3 0 0 3 3 3 1 Histone chaperone domain CHZ DNA_pol_phi PF04931.13 KIK69097.1 - 0.36 8.9 31.2 0.4 8.7 31.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KIK69097.1 - 9.5 5.4 26.8 11 5.3 26.8 1.0 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 KIK69098.1 - 0.054 13.5 1.2 0.094 12.7 1.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 KIK69098.1 - 0.37 10.4 3.1 0.7 9.5 3.1 1.4 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 KIK69098.1 - 0.39 10.4 5.0 0.8 9.4 5.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KIK69098.1 - 0.48 9.7 3.1 0.7 9.2 3.1 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KIK69098.1 - 3.4 5.7 7.0 4.8 5.2 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KIK69098.1 - 5.5 7.4 12.0 10 6.6 12.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 KIK69098.1 - 9.2 6.6 9.0 20 5.5 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SKI PF01202.22 KIK69099.1 - 8.6e-10 39.0 0.0 1.4e-07 31.7 0.0 2.3 2 1 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 KIK69099.1 - 1.8e-08 35.0 0.0 6.2e-08 33.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK69099.1 - 8.8e-07 29.2 0.0 4e-05 23.8 0.0 2.5 2 1 1 3 3 3 1 AAA domain Cytidylate_kin2 PF13189.6 KIK69099.1 - 0.0063 16.7 0.0 0.044 13.9 0.0 2.1 2 1 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 KIK69099.1 - 0.012 16.0 0.1 0.05 14.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK69099.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase dNK PF01712.19 KIK69099.1 - 0.016 15.0 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Thymidylate_kin PF02223.17 KIK69099.1 - 0.027 14.2 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 KIK69099.1 - 0.041 13.2 0.1 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KIK69099.1 - 0.042 14.3 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK69099.1 - 0.045 14.1 0.2 0.083 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK69099.1 - 0.06 13.6 0.5 0.2 11.9 0.2 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIK69099.1 - 0.097 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KIK69099.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK69099.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIK69099.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Proteasome PF00227.26 KIK69100.1 - 1.7e-55 187.4 0.5 3.4e-55 186.5 0.5 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK69100.1 - 1.5e-13 50.1 0.1 2.9e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CDK2AP PF09806.9 KIK69101.1 - 4.2 7.4 0.0 4.2 7.4 0.0 3.4 3 1 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Rpr2 PF04032.16 KIK69104.1 - 2.3e-15 56.6 0.8 2.3e-15 56.6 0.8 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Oxidored_FMN PF00724.20 KIK69105.1 - 3e-98 329.3 0.0 3.4e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FtsK_SpoIIIE PF01580.18 KIK69106.1 - 0.0032 16.9 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family RHSP PF07999.11 KIK69106.1 - 0.0068 15.3 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon hot spot protein ATPase_2 PF01637.18 KIK69106.1 - 0.035 14.0 0.0 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK69106.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK69106.1 - 0.17 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Y_phosphatase PF00102.27 KIK69107.1 - 0.00054 19.6 0.0 0.00064 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rsbr_N PF08678.10 KIK69110.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Rsbr N terminal Muskelin_N PF06588.11 KIK69111.1 - 2.9e-57 193.8 1.0 4.5e-57 193.2 1.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_4 PF13418.6 KIK69111.1 - 5.8e-29 99.9 0.0 4.1e-09 36.3 0.0 6.9 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK69111.1 - 2.6e-27 94.3 0.2 1.1e-09 38.0 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KIK69111.1 - 5.1e-20 71.3 9.1 6.6e-11 42.2 0.0 7.0 8 0 0 8 8 8 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK69111.1 - 1.5e-19 69.5 1.4 1.9e-05 24.7 0.1 5.7 3 2 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KIK69111.1 - 1.7e-18 65.9 2.9 7.4e-08 31.9 0.1 5.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KIK69111.1 - 1e-09 38.0 2.3 6.4e-06 25.9 0.1 5.2 4 1 0 4 4 4 1 Kelch motif F5_F8_type_C PF00754.25 KIK69111.1 - 6.4e-05 23.1 0.0 0.00024 21.2 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain Sad1_UNC PF07738.13 KIK69111.1 - 0.016 15.3 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Arrestin_C PF02752.22 KIK69112.1 - 8.3e-10 39.2 1.3 9.8e-07 29.3 0.7 3.2 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIK69112.1 - 1.9e-08 34.5 0.0 4.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KIK69112.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Pyridoxal_deC PF00282.19 KIK69113.1 - 1.4e-16 60.2 0.0 2.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIK69113.1 - 1.3e-08 34.2 0.0 8.5e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK69113.1 - 0.00047 19.6 0.3 0.00072 19.0 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Prefoldin_2 PF01920.20 KIK69114.1 - 4.4e-22 78.0 4.2 6.5e-22 77.5 4.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KIK69114.1 - 0.0031 17.4 5.3 0.31 10.9 0.3 2.2 1 1 1 2 2 2 2 Prefoldin subunit Spc24 PF08286.11 KIK69114.1 - 0.025 14.8 7.6 0.076 13.3 0.1 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Spore_III_AB PF09548.10 KIK69114.1 - 0.042 14.0 1.8 0.087 12.9 1.8 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FTA4 PF13093.6 KIK69114.1 - 0.19 11.6 3.3 0.28 11.1 3.3 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DASH_Dam1 PF08653.10 KIK69114.1 - 0.31 10.9 2.6 4.4 7.2 0.4 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 APG6_N PF17675.1 KIK69114.1 - 0.35 11.4 12.6 0.69 10.4 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIK69114.1 - 0.82 9.5 10.1 0.85 9.4 0.7 2.4 1 1 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 KIK69114.1 - 2.4 8.5 13.9 7.5 6.9 1.9 2.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF4140 PF13600.6 KIK69114.1 - 3.4 8.2 7.6 4.8 7.7 1.5 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PCRF PF03462.18 KIK69114.1 - 3.9 7.3 8.4 6.7 6.5 8.4 1.4 1 1 0 1 1 1 0 PCRF domain FapA PF03961.13 KIK69114.1 - 7.7 5.0 6.7 8.8 4.8 1.9 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A peroxidase PF00141.23 KIK69115.1 - 2.1e-46 158.5 0.0 3.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ISAV_HA PF06215.11 KIK69116.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin RPT PF13446.6 KIK69119.1 - 0.0071 16.3 0.3 0.018 15.0 0.3 1.7 1 0 0 1 1 1 1 A repeated domain in UCH-protein YL1 PF05764.13 KIK69119.1 - 0.021 14.9 5.0 0.046 13.8 5.0 1.7 1 0 0 1 1 1 0 YL1 nuclear protein Roughex PF06020.11 KIK69119.1 - 0.23 10.5 4.5 0.34 10.0 4.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein GATase PF00117.28 KIK69120.1 - 1.2e-08 34.9 0.5 1.1e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK69120.1 - 0.023 14.5 0.5 0.069 12.9 0.5 1.9 1 1 0 1 1 1 0 Peptidase C26 Gpr1_Fun34_YaaH PF01184.19 KIK69121.1 - 5.3e-35 120.9 22.8 6.5e-35 120.6 22.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1375 PF07119.12 KIK69121.1 - 0.00069 20.0 1.0 0.0034 17.8 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1375) GATase PF00117.28 KIK69123.1 - 1.4e-05 25.0 0.4 0.00015 21.6 0.4 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Unstab_antitox PF09720.10 KIK69123.1 - 0.045 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative addiction module component Peptidase_C26 PF07722.13 KIK69123.1 - 0.048 13.4 0.2 0.19 11.4 0.0 2.0 2 1 0 2 2 2 0 Peptidase C26 GFO_IDH_MocA PF01408.22 KIK69124.1 - 1.1e-13 52.1 0.0 2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 KIK69124.1 - 0.44 11.3 2.5 0.89 10.3 0.3 2.5 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Macoilin PF09726.9 KIK69125.1 - 0.00074 18.2 12.6 0.00074 18.2 12.6 4.2 2 1 2 4 4 4 1 Macoilin family SGP PF17228.2 KIK69125.1 - 0.022 15.6 9.8 0.022 15.6 9.8 2.7 2 0 0 2 2 2 0 Sulphur globule protein zf-GRF PF06839.12 KIK69126.1 - 1.9e-25 88.7 18.7 2.4e-10 40.3 3.8 3.6 3 0 0 3 3 3 3 GRF zinc finger zf-CCHC PF00098.23 KIK69126.1 - 5.5e-12 45.2 16.0 7.2e-07 29.0 1.5 3.2 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 KIK69126.1 - 1.2e-06 28.3 8.8 0.0022 17.9 1.0 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 KIK69126.1 - 0.00026 20.6 6.7 0.17 11.6 0.5 2.7 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KIK69126.1 - 0.00077 19.2 14.8 0.023 14.5 4.8 2.6 2 0 0 2 2 2 2 Zinc knuckle FXMRP1_C_core PF12235.8 KIK69126.1 - 1.6 9.4 7.6 5.5 7.6 7.6 2.0 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Topoisom_bac PF01131.20 KIK69127.1 - 4.2e-111 371.9 0.0 5.1e-111 371.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KIK69127.1 - 2.4e-19 69.5 0.0 2e-18 66.5 0.0 2.5 3 0 0 3 3 3 1 Toprim domain UTP25 PF06862.12 KIK69128.1 - 4.9e-165 549.9 0.1 5.7e-165 549.7 0.1 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KIK69128.1 - 0.00038 20.3 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AroM PF07302.11 KIK69128.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 AroM protein Autophagy_N PF03986.13 KIK69129.1 - 3.8e-42 143.5 0.2 7.9e-42 142.5 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KIK69129.1 - 2.6e-18 66.4 0.4 5.1e-18 65.4 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KIK69129.1 - 1.2e-12 47.1 2.9 2.4e-12 46.1 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Pup_ligase PF03136.15 KIK69131.1 - 0.07 12.2 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein Acetyltransf_1 PF00583.25 KIK69133.1 - 1.5e-11 44.6 0.0 2.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK69133.1 - 1.9e-09 37.5 0.0 2.1e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK69133.1 - 8.4e-07 29.3 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK69133.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK69133.1 - 0.0025 17.7 0.1 0.0042 17.0 0.1 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 KIK69133.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 KIK69133.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 KIK69133.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Meth_synt_2 PF01717.18 KIK69134.1 - 1.5e-10 40.9 0.0 9.6e-08 31.7 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIK69134.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain MFS_1 PF07690.16 KIK69135.1 - 1.2e-31 109.9 33.4 1.4e-31 109.7 31.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily EMC3_TMCO1 PF01956.16 KIK69135.1 - 0.22 11.2 1.9 18 5.0 0.2 2.7 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like OsmC PF02566.19 KIK69136.1 - 1.3e-11 44.8 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein MMS1_N PF10433.9 KIK69137.1 - 2.4e-157 524.5 0.0 4.2e-157 523.7 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIK69137.1 - 2.1e-89 300.0 0.0 1.3e-88 297.4 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region zf-MYND PF01753.18 KIK69139.1 - 1.4e-09 37.8 8.7 2.9e-09 36.8 8.7 1.5 1 0 0 1 1 1 1 MYND finger AP3D1 PF06375.11 KIK69139.1 - 0.0057 16.9 8.9 0.011 16.0 8.9 1.4 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 RNA_pol_Rpc4 PF05132.14 KIK69139.1 - 0.25 11.7 4.6 0.42 11.0 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_S49_N PF08496.10 KIK69139.1 - 0.28 11.2 8.1 0.54 10.3 8.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Meleagrin PF08189.11 KIK69139.1 - 0.55 10.0 6.5 1.2 8.9 6.5 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family zf-C6H2 PF15801.5 KIK69139.1 - 2.6 8.4 9.4 5.5 7.4 9.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Presenilin PF01080.17 KIK69139.1 - 4.1 6.1 3.8 5.7 5.6 3.8 1.1 1 0 0 1 1 1 0 Presenilin Cytomega_UL84 PF06284.11 KIK69139.1 - 8.4 4.7 8.8 16 3.8 7.4 2.0 3 0 0 3 3 3 0 Cytomegalovirus UL84 protein Sec34 PF04136.15 KIK69141.1 - 0.0016 18.3 0.4 0.0022 17.9 0.4 1.2 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 KIK69141.1 - 0.028 14.2 0.6 0.035 13.9 0.6 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 KIK69141.1 - 0.35 11.3 4.7 0.7 10.4 4.7 1.4 1 1 0 1 1 1 0 Cell division protein ZapB FAD_binding_4 PF01565.23 KIK69142.1 - 3e-23 82.1 1.1 4.9e-23 81.4 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK69142.1 - 4.1e-10 39.6 0.5 8.6e-10 38.6 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KIK69143.1 - 1.8e-25 89.7 27.0 8.5e-13 47.9 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PVL_ORF50 PF07768.11 KIK69145.1 - 6.2 7.2 14.0 0.17 12.2 6.8 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family zf-C2H2_jaz PF12171.8 KIK69146.1 - 4.1e-16 58.8 18.2 0.00032 20.9 0.5 5.4 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK69146.1 - 1.1e-15 57.0 18.5 0.0064 17.2 0.8 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KIK69146.1 - 3.1e-11 43.3 20.3 9.1e-05 22.7 1.0 4.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIK69146.1 - 5.7e-11 42.3 24.3 0.0073 16.7 1.7 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK69146.1 - 4.4e-10 39.8 14.9 0.063 13.6 0.2 5.0 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KIK69146.1 - 5e-09 35.9 21.4 1.4e-05 24.9 0.5 4.8 5 0 0 5 5 4 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KIK69146.1 - 2.3e-07 30.5 2.0 0.64 9.9 0.0 4.2 4 0 0 4 4 4 2 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 KIK69146.1 - 5.2e-05 23.5 13.4 0.53 10.8 0.1 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_9 PF16293.5 KIK69146.1 - 9e-05 22.2 13.4 0.31 10.9 0.5 4.3 3 1 1 4 4 4 2 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KIK69146.1 - 0.0038 17.1 22.2 0.35 10.8 0.1 5.1 6 0 0 6 6 5 3 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KIK69146.1 - 0.0041 17.4 11.9 0.41 11.0 0.6 3.2 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-Di19 PF05605.12 KIK69146.1 - 0.0047 17.2 14.1 0.22 11.8 1.5 3.7 2 2 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KIK69146.1 - 0.0056 17.1 6.7 0.091 13.2 0.1 3.9 4 0 0 4 4 4 1 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_5 PF13719.6 KIK69146.1 - 0.018 14.8 6.9 1.4 8.7 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 KIK69146.1 - 0.018 15.1 3.5 6.7 6.9 1.9 3.6 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HE PF16278.5 KIK69146.1 - 0.04 14.4 12.0 4.2 7.9 0.1 3.7 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 KIK69146.1 - 0.046 13.8 10.1 1.6 8.9 0.2 4.4 4 1 1 5 5 5 0 Zic proteins zinc finger domain DehI PF10778.9 KIK69146.1 - 0.049 13.8 0.1 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI zf-CHY PF05495.12 KIK69146.1 - 0.05 14.1 1.2 0.05 14.1 1.2 3.9 2 1 1 3 3 2 0 CHY zinc finger Stc1 PF12898.7 KIK69146.1 - 0.19 12.3 13.4 1.1 9.9 2.6 3.5 1 1 2 3 3 3 0 Stc1 domain FOXP-CC PF16159.5 KIK69146.1 - 0.42 11.3 7.4 3.2 8.4 0.2 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KIK69146.1 - 0.43 10.4 13.5 8 6.3 0.2 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type DZR PF12773.7 KIK69146.1 - 0.71 9.9 15.7 4.1 7.5 1.3 3.7 2 2 1 3 3 3 0 Double zinc ribbon C1_4 PF07975.12 KIK69146.1 - 0.87 9.9 15.0 0.14 12.4 1.5 3.3 2 1 0 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KIK69146.1 - 1 9.5 16.3 1.1 9.4 0.4 4.4 2 2 3 5 5 5 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KIK69146.1 - 1.2 9.1 10.6 3.2 7.8 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 KIK69146.1 - 1.6 9.0 6.1 6.2 7.1 0.2 3.9 4 0 0 4 4 4 0 C4-type zinc ribbon domain DUF2256 PF10013.9 KIK69146.1 - 2 8.6 12.3 35 4.6 0.1 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_4 PF14570.6 KIK69146.1 - 5.6 6.8 17.1 0.61 9.9 2.2 3.6 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain CpXC PF14353.6 KIK69146.1 - 8.9 6.4 7.3 7 6.7 0.1 2.9 3 1 0 3 3 2 0 CpXC protein zf-C2H2_4 PF13894.6 KIK69147.1 - 1.2e-14 53.8 17.8 0.009 16.8 0.3 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK69147.1 - 5.8e-14 51.9 16.4 0.0024 18.1 0.4 5.2 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK69147.1 - 4.3e-11 42.8 15.5 0.0013 19.0 0.8 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIK69147.1 - 5.8e-11 42.2 22.3 0.0036 17.7 0.3 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK69147.1 - 3.3e-10 40.2 15.1 0.0014 19.0 6.6 4.9 2 2 1 3 3 3 2 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 KIK69147.1 - 3.2e-09 36.5 1.8 0.54 10.1 0.2 4.5 4 0 0 4 4 4 3 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KIK69147.1 - 1.1e-07 31.7 22.7 6.1e-05 22.9 0.4 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK69147.1 - 6e-05 22.8 14.5 1.4 8.9 0.6 5.3 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 KIK69147.1 - 0.00028 20.6 15.2 0.73 9.7 0.1 4.7 3 2 2 5 5 4 2 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KIK69147.1 - 0.00039 20.7 13.4 0.054 13.8 1.0 3.9 2 2 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIK69147.1 - 0.0039 17.5 19.4 0.43 11.1 0.5 4.5 5 0 0 5 5 3 3 Zinc-finger double domain TRAF6_Z2 PF18048.1 KIK69147.1 - 0.0057 16.7 0.1 8.8 6.5 0.0 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf_ZIC PF18366.1 KIK69147.1 - 0.0081 16.2 6.4 5.1 7.3 0.1 4.4 4 1 1 5 5 5 1 Zic proteins zinc finger domain zf-C2HE PF16278.5 KIK69147.1 - 0.0083 16.6 13.0 1.2 9.6 0.1 4.3 2 2 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-CHY PF05495.12 KIK69147.1 - 0.022 15.2 1.1 0.022 15.2 1.1 3.7 2 1 2 4 4 4 0 CHY zinc finger Zn-C2H2_12 PF18112.1 KIK69147.1 - 0.046 14.2 4.4 0.052 14.0 0.1 2.9 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 KIK69147.1 - 0.069 13.5 8.5 1.8 8.9 0.6 2.5 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-TFIIB PF13453.6 KIK69147.1 - 0.16 11.3 3.0 2.6 7.4 0.3 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2H2_11 PF16622.5 KIK69147.1 - 0.16 11.7 7.6 10 6.0 0.5 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zinc_ribbon_5 PF13719.6 KIK69147.1 - 0.21 11.4 2.8 6.7 6.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.12 KIK69147.1 - 0.31 11.3 13.2 0.26 11.6 1.1 3.3 3 1 1 4 4 3 0 TFIIH C1-like domain zinc_ribbon_9 PF14369.6 KIK69147.1 - 0.37 11.1 21.6 29 5.0 6.0 5.0 3 2 0 3 3 3 0 zinc-ribbon DUF2256 PF10013.9 KIK69147.1 - 0.39 10.9 10.0 39 4.5 0.0 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KIK69147.1 - 0.48 10.4 9.5 0.87 9.6 0.7 3.0 2 2 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2225 PF09986.9 KIK69147.1 - 0.64 9.7 3.6 5.9 6.5 0.1 3.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_4 PF14570.6 KIK69147.1 - 1.1 9.1 12.4 0.71 9.7 2.6 3.6 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 KIK69147.1 - 2 8.6 15.2 1.5 9.0 0.9 4.2 2 2 3 5 5 5 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KIK69147.1 - 4.8 7.2 14.9 24 5.0 2.4 4.3 2 2 0 2 2 2 0 zinc-ribbons FOXP-CC PF16159.5 KIK69147.1 - 4.8 7.9 10.0 72 4.1 0.4 4.4 2 2 3 5 5 5 0 FOXP coiled-coil domain LIM PF00412.22 KIK69147.1 - 5.5 7.3 16.9 32 4.8 4.3 4.5 2 2 3 5 5 5 0 LIM domain zf-C3HC4_3 PF13920.6 KIK69147.1 - 9.6 6.2 17.1 44 4.0 3.6 4.4 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Terpene_synth_C PF03936.16 KIK69148.1 - 3.4e-05 23.3 0.1 9.5e-05 21.9 0.1 1.9 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain AFG1_ATPase PF03969.16 KIK69150.1 - 5.1e-54 183.5 0.0 1.3e-48 165.8 0.0 3.3 3 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 KIK69150.1 - 3.9e-08 33.9 0.0 1.2e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK69150.1 - 0.0002 21.6 0.0 0.00087 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK69150.1 - 0.00098 19.5 0.0 0.0031 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK69150.1 - 0.0026 17.5 0.0 1.2 8.8 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.14 KIK69150.1 - 0.0076 16.3 0.0 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KIK69150.1 - 0.0083 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KIK69150.1 - 0.017 15.5 0.0 0.1 13.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIK69150.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Plavaka PF18759.1 KIK69151.1 - 1.3e-41 142.9 0.0 2.3e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase HALZ PF02183.18 KIK69152.1 - 0.12 12.7 0.5 0.26 11.6 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper YfzA PF14118.6 KIK69154.1 - 0.037 14.4 2.4 0.041 14.3 2.4 1.1 1 0 0 1 1 1 0 YfzA-like protein AlkA_N PF06029.11 KIK69155.1 - 0.035 14.4 0.9 0.066 13.5 0.9 1.5 1 1 0 1 1 1 0 AlkA N-terminal domain HSP20 PF00011.21 KIK69156.1 - 8.9e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family F-box-like PF12937.7 KIK69158.1 - 0.00039 20.2 2.0 0.0025 17.6 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK69159.1 - 0.00013 21.8 2.3 0.00016 21.5 0.7 2.1 2 0 0 2 2 2 1 F-box-like CHD5 PF04420.14 KIK69161.1 - 1.7e-55 187.2 0.4 2e-55 187.0 0.4 1.0 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_6 PF01441.19 KIK69161.1 - 0.039 14.0 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 Lipoprotein BHD_2 PF10404.9 KIK69161.1 - 0.085 13.8 0.0 1.3 10.1 0.0 2.2 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Malate_synthase PF01274.22 KIK69162.1 - 1.3e-200 667.2 0.0 1.5e-200 666.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KIK69162.1 - 0.00096 18.3 0.0 0.0024 17.1 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Abhydrolase_1 PF00561.20 KIK69163.1 - 8.2e-15 55.1 0.1 1.2e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69163.1 - 6.2e-08 33.5 1.0 6.2e-08 33.5 1.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK69163.1 - 4.4e-07 29.4 0.0 7.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIK69163.1 - 0.0036 17.3 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 KIK69163.1 - 0.02 13.6 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.21 KIK69163.1 - 0.045 13.2 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 KIK69163.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.4 2 0 0 2 2 2 0 Dienelactone hydrolase family LRR_6 PF13516.6 KIK69164.1 - 0.0043 17.0 0.1 0.062 13.4 0.0 3.0 2 0 0 2 2 2 1 Leucine Rich repeat F-box-like_2 PF13013.6 KIK69164.1 - 0.012 15.6 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KIK69165.1 - 5.7e-07 29.3 0.7 1.9e-06 27.7 0.2 2.2 2 0 0 2 2 2 1 F-box-like Glyoxal_oxid_N PF07250.11 KIK69166.1 - 9.9e-33 113.3 0.2 2e-25 89.4 0.0 3.7 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK69166.1 - 1.2e-22 80.0 0.2 2.5e-22 79.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KIK69166.1 - 0.01 15.8 1.6 0.68 10.0 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain FYRN PF05964.14 KIK69166.1 - 0.3 11.0 1.2 0.95 9.4 1.2 1.8 1 0 0 1 1 1 0 F/Y-rich N-terminus ABC1 PF03109.16 KIK69169.1 - 1.6e-21 76.6 0.0 3.3e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KIK69169.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ndc1_Nup PF09531.10 KIK69169.1 - 0.92 8.1 5.5 1.3 7.6 5.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TetR_C_14 PF17754.1 KIK69170.1 - 0.0029 17.5 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 MftR C-terminal domain Lipoprotein_16 PF03923.13 KIK69170.1 - 0.035 13.7 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized lipoprotein Aldedh PF00171.22 KIK69171.1 - 4.3e-183 609.0 2.5 4.9e-183 608.9 2.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK69171.1 - 0.12 11.4 0.0 0.29 10.1 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Nkap_C PF06047.11 KIK69172.1 - 1.2e-43 147.4 5.5 1.4e-43 147.2 5.5 1.0 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Ribosomal_S17e PF00833.18 KIK69172.1 - 0.12 12.3 3.0 0.16 11.9 3.0 1.3 1 1 0 1 1 1 0 Ribosomal S17 Pkinase PF00069.25 KIK69175.1 - 2.4e-21 76.3 0.0 5.4e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69175.1 - 2.4e-12 46.7 0.0 6.6e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KIK69175.1 - 0.051 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK69175.1 - 0.082 12.8 0.4 0.25 11.2 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK69175.1 - 0.14 11.5 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Xan_ur_permease PF00860.20 KIK69176.1 - 6.5e-29 100.8 29.0 5.2e-18 64.9 10.9 2.7 2 1 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 KIK69176.1 - 0.0078 16.6 5.1 0.0078 16.6 5.1 2.9 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily Cleaved_Adhesin PF07675.11 KIK69177.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Cleaved Adhesin Domain CMAS PF02353.20 KIK69178.1 - 3.8e-36 124.8 0.2 5.1e-36 124.4 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK69178.1 - 3.4e-13 50.1 0.0 6.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK69178.1 - 3.7e-12 46.7 0.0 8.3e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69178.1 - 5.8e-11 42.4 0.0 9.3e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK69178.1 - 1.3e-09 38.1 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK69178.1 - 1.8e-08 35.0 0.0 3.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK69178.1 - 8.1e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 KIK69178.1 - 5e-06 25.8 0.0 7.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KIK69178.1 - 9.1e-06 25.2 0.0 4.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KIK69178.1 - 6.4e-05 22.5 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 KIK69178.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F GidB PF02527.15 KIK69178.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.18 KIK69178.1 - 0.028 13.7 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KIK69178.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KIK69178.1 - 0.032 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KIK69178.1 - 0.049 13.8 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KIK69178.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KIK69178.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 KIK69178.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HET PF06985.11 KIK69181.1 - 2.1e-10 41.1 0.3 5e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Tubulin PF00091.25 KIK69185.1 - 1.4e-05 25.4 0.0 1.4e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain HET PF06985.11 KIK69186.1 - 9.1e-09 35.8 0.6 1.7e-06 28.5 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 KIK69188.1 - 6.5e-09 36.3 0.4 1.2e-07 32.2 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RdRP PF05183.12 KIK69189.1 - 8.2e-100 335.1 0.0 1.2e-99 334.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase K_oxygenase PF13434.6 KIK69190.1 - 1.3e-14 54.2 0.0 5.2e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK69190.1 - 1.8e-12 47.1 0.0 5.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK69190.1 - 1.2e-11 43.8 0.0 8.5e-09 34.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK69190.1 - 2.8e-09 36.7 0.0 0.041 13.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK69190.1 - 2.1e-07 31.1 0.6 9.8e-06 25.7 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK69190.1 - 1.3e-06 28.3 2.2 0.019 14.5 0.3 3.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIK69190.1 - 1.7e-05 24.4 0.0 0.6 9.3 0.0 3.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KIK69190.1 - 3.2e-05 24.0 0.7 0.054 13.5 0.0 3.5 3 1 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIK69190.1 - 0.0031 17.6 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KIK69190.1 - 0.0051 16.1 0.9 0.077 12.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KIK69190.1 - 0.011 15.0 0.7 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KIK69190.1 - 0.013 16.0 0.2 0.12 12.9 0.0 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK69190.1 - 0.017 14.2 0.2 0.017 14.2 0.2 2.1 4 0 0 4 4 4 0 FAD binding domain HI0933_like PF03486.14 KIK69190.1 - 0.022 13.5 0.6 2.1 7.0 0.1 2.8 4 0 0 4 4 4 0 HI0933-like protein ApbA PF02558.16 KIK69190.1 - 0.035 13.8 0.0 1.4 8.5 0.0 2.9 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KIK69190.1 - 0.04 14.4 0.0 10 6.6 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KIK69190.1 - 0.075 12.1 0.2 9.6 5.2 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A F420_oxidored PF03807.17 KIK69190.1 - 0.12 12.9 0.2 23 5.7 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ISG65-75 PF11727.8 KIK69192.1 - 0.036 13.3 0.1 0.043 13.0 0.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Rnk_N PF14760.6 KIK69192.1 - 0.26 11.8 2.3 0.44 11.1 0.3 2.1 2 0 0 2 2 2 0 Rnk N-terminus F-box-like PF12937.7 KIK69193.1 - 6.7e-07 29.1 0.9 2.1e-06 27.5 0.9 1.9 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KIK69195.1 - 1.9e-36 125.7 40.1 1.9e-36 125.7 40.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK69195.1 - 1.9e-08 33.6 8.9 1.9e-08 33.6 8.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter BTB PF00651.31 KIK69196.1 - 6.8e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.9 KIK69197.1 - 1.4e-39 135.8 0.0 2e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Methyltransf_25 PF13649.6 KIK69198.1 - 7.6e-19 68.2 0.0 1.3e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK69198.1 - 2e-17 63.6 0.0 3.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK69198.1 - 5.1e-16 58.9 0.0 6.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69198.1 - 2.7e-09 37.0 0.0 3.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK69198.1 - 3.7e-09 37.2 0.0 9.5e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KIK69198.1 - 8.8e-06 25.2 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KIK69198.1 - 3.4e-05 23.3 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK69198.1 - 0.0048 16.7 0.0 0.0084 15.9 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0146 PF03686.13 KIK69198.1 - 0.0071 16.2 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0146) TPMT PF05724.11 KIK69198.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KIK69198.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 KIK69198.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TehB PF03848.14 KIK69198.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB BTB PF00651.31 KIK69199.1 - 6.4e-08 32.8 0.0 8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Leu_zip PF15294.6 KIK69201.1 - 0.0025 17.4 0.7 0.0038 16.8 0.7 1.3 1 0 0 1 1 1 1 Leucine zipper DUF5335 PF17269.2 KIK69201.1 - 0.0084 16.0 0.5 0.044 13.6 0.1 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5335) ERM PF00769.19 KIK69201.1 - 3 7.6 10.9 2.4 7.9 4.4 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Syntaxin_2 PF14523.6 KIK69202.1 - 3.5e-19 69.1 6.5 2.7e-18 66.2 3.7 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KIK69202.1 - 5.6e-12 45.5 0.6 5.6e-12 45.5 0.6 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KIK69202.1 - 4.5e-05 23.2 8.4 0.00013 21.7 8.4 1.9 1 1 0 1 1 1 1 Syntaxin ODV-E18 PF10717.9 KIK69202.1 - 0.023 14.5 0.3 0.07 13.0 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Prominin PF05478.11 KIK69202.1 - 0.056 11.4 3.0 0.24 9.3 3.1 1.9 1 1 0 1 1 1 0 Prominin DUF4337 PF14235.6 KIK69202.1 - 0.53 10.4 3.4 4.3 7.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) T2SSF PF00482.23 KIK69202.1 - 0.82 9.6 4.2 3.1 7.8 1.4 2.4 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Synaptobrevin PF00957.21 KIK69202.1 - 1.8 8.4 6.0 0.44 10.4 0.6 2.7 2 2 1 3 3 3 0 Synaptobrevin SET PF00856.28 KIK69203.1 - 1.9e-07 31.6 0.0 1.6e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 SET domain 2OG-FeII_Oxy PF03171.20 KIK69204.1 - 1.8e-13 50.9 0.0 3.3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK69204.1 - 4.3e-13 50.0 0.0 8.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_28 PF00295.17 KIK69205.1 - 6.6e-45 153.6 0.7 9e-45 153.1 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KIK69205.1 - 1.4e-08 34.8 9.1 2.8e-05 24.1 0.0 3.8 2 1 2 4 4 4 3 Pectate lyase superfamily protein Lustrin_cystein PF14625.6 KIK69206.1 - 0.37 11.2 9.9 0.54 10.7 9.6 1.5 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain p450 PF00067.22 KIK69207.1 - 7.1e-73 245.9 0.0 1.6e-72 244.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 SARAF PF06682.12 KIK69209.1 - 0.89 9.1 7.7 4.3 6.9 0.6 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF802 PF05650.11 KIK69209.1 - 2 8.9 5.1 4 8.0 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Isochorismatase PF00857.20 KIK69211.1 - 1.7e-23 83.7 0.0 3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 KIK69211.1 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KIK69212.1 - 2e-09 37.2 1.1 6.4e-09 35.6 1.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69212.1 - 0.0099 15.7 1.8 3.5 7.6 0.0 3.1 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KIK69213.1 - 4.1e-09 36.2 3.6 2.1e-08 33.9 2.0 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK69213.1 - 0.013 15.4 0.3 0.039 13.8 0.3 1.9 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 KIK69213.1 - 0.26 11.1 3.1 6.5 6.6 0.3 4.3 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 KIK69214.1 - 2.3e-11 43.4 2.1 5.3e-11 42.2 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK69214.1 - 7.2e-05 22.6 0.2 0.0003 20.6 0.2 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK69215.1 - 1.7e-09 37.4 1.7 5.2e-09 35.9 1.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK69215.1 - 8.5e-05 22.8 2.6 2.8 8.5 0.0 5.5 3 2 1 5 5 5 2 Leucine Rich repeats (2 copies) FKBP_C PF00254.28 KIK69216.1 - 2.2e-32 111.2 0.0 2.8e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CoA_binding_2 PF13380.6 KIK69217.1 - 1.2e-28 99.9 0.0 1.3e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Zn_clus PF00172.18 KIK69219.1 - 9e-07 28.9 10.1 9e-07 28.9 10.1 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA-ATPase_like PF09820.9 KIK69220.1 - 2.9e-13 49.9 0.0 3.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Predicted AAA-ATPase P22_AR_C PF10548.9 KIK69220.1 - 0.075 13.2 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain BACK PF07707.15 KIK69220.1 - 0.11 12.7 0.2 3.3 7.9 0.1 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch AAA_16 PF13191.6 KIK69220.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CoA_binding_2 PF13380.6 KIK69221.1 - 3.3e-29 101.7 0.0 3.8e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_92 PF07971.12 KIK69222.1 - 1e-117 393.9 0.6 1.2e-117 393.7 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK69222.1 - 5.3e-51 173.8 0.2 9.2e-51 173.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MFS_1 PF07690.16 KIK69223.1 - 9.5e-37 126.7 51.1 9.5e-37 126.7 51.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2788 PF10981.8 KIK69223.1 - 0.45 10.6 5.3 13 5.9 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) OATP PF03137.20 KIK69223.1 - 0.58 8.4 14.9 0.01 14.2 0.9 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KIK69224.1 - 6.1e-39 133.9 42.5 1.2e-38 132.9 42.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KIK69224.1 - 0.67 8.2 8.6 0.024 12.9 2.1 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KIK69225.1 - 5.3e-40 137.4 50.5 9.8e-40 136.5 50.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK69225.1 - 2.7e-09 36.0 28.9 7.6e-09 34.5 28.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 2-Hacid_dh_C PF02826.19 KIK69227.1 - 1.5e-55 187.3 0.0 2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK69227.1 - 8.5e-08 31.9 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK69227.1 - 5.7e-06 26.6 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIK69227.1 - 3.6e-05 23.4 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KIK69227.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 KIK69227.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 KIK69227.1 - 0.068 13.2 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Macoilin PF09726.9 KIK69228.1 - 0.065 11.8 2.2 0.088 11.4 2.2 1.1 1 0 0 1 1 1 0 Macoilin family Syndecan PF01034.20 KIK69228.1 - 0.094 12.6 1.6 0.18 11.8 1.6 1.3 1 0 0 1 1 1 0 Syndecan domain Plasmodium_Vir PF05795.11 KIK69228.1 - 0.58 9.5 6.8 0.048 13.1 1.8 1.7 2 1 0 2 2 2 0 Plasmodium vivax Vir protein NPV_P10 PF05531.12 KIK69230.1 - 0.066 13.7 8.0 8.3 7.0 0.1 4.6 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Abhydrolase_1 PF00561.20 KIK69231.1 - 4e-11 43.1 0.0 7.6e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69231.1 - 1.1e-07 32.7 0.6 1.9e-07 31.9 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK69231.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KIK69231.1 - 0.0026 17.1 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIK69231.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KIK69231.1 - 0.033 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ndr PF03096.14 KIK69231.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family GGA_N-GAT PF18308.1 KIK69232.1 - 0.12 12.0 0.1 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 GGA N-GAT domain Bax1-I PF01027.20 KIK69234.1 - 3e-47 161.1 23.4 3.4e-47 160.9 23.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KIK69234.1 - 3.6e-05 23.4 15.2 0.0003 20.4 15.2 2.2 1 1 0 1 1 1 1 Bax inhibitor 1 like Cu-oxidase PF00394.22 KIK69235.1 - 6.5e-50 169.4 0.5 1.6e-43 148.6 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK69235.1 - 9.1e-38 129.1 4.8 7.8e-36 122.8 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK69235.1 - 1.1e-34 119.0 4.7 1.3e-32 112.3 0.2 3.5 3 1 0 3 3 3 1 Multicopper oxidase Pkinase_fungal PF17667.1 KIK69236.1 - 4.8e-51 173.8 0.0 7e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK69236.1 - 0.00028 20.4 0.0 0.00093 18.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69236.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Abhydrolase_3 PF07859.13 KIK69237.1 - 7.8e-19 68.4 0.0 8e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK69237.1 - 0.0082 15.1 0.0 0.021 13.7 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase GMC_oxred_N PF00732.19 KIK69240.1 - 4.3e-67 226.6 0.0 5.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK69240.1 - 2.1e-30 106.1 0.0 1.2e-29 103.7 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK69240.1 - 9e-06 25.0 0.3 3.8e-05 23.0 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK69240.1 - 0.00035 20.8 0.2 0.00087 19.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK69240.1 - 0.00066 19.4 1.4 0.0029 17.2 1.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK69240.1 - 0.0035 16.6 0.1 0.032 13.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK69240.1 - 0.0083 15.2 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KIK69240.1 - 0.047 12.4 0.0 0.094 11.4 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein SARS_lipid_bind PF09399.10 KIK69240.1 - 0.068 13.3 0.0 26 5.1 0.0 3.2 2 1 1 3 3 3 0 SARS lipid binding protein Pyr_redox_3 PF13738.6 KIK69240.1 - 0.11 11.8 2.1 4.9 6.3 2.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK69240.1 - 0.18 11.0 0.1 0.31 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family RhlB PF12300.8 KIK69241.1 - 0.34 11.0 9.3 0.16 12.1 6.6 1.7 1 1 1 2 2 2 0 ATP-dependent RNA helicase RhlB AAA_16 PF13191.6 KIK69242.1 - 0.015 15.7 0.0 0.049 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KIK69242.1 - 0.093 12.6 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KIK69242.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIK69242.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Epimerase PF01370.21 KIK69243.1 - 3.2e-19 69.3 0.1 1.3e-18 67.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK69243.1 - 2e-15 57.2 0.0 3.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK69243.1 - 3.8e-12 45.8 0.0 6e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK69243.1 - 1.2e-10 41.0 0.3 6.1e-08 32.2 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK69243.1 - 1.1e-05 25.0 0.4 7.5e-05 22.3 0.4 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIK69243.1 - 1.2e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIK69243.1 - 0.00032 19.9 0.0 0.00045 19.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK69243.1 - 0.0035 16.8 0.1 0.15 11.5 0.1 2.9 2 1 0 2 2 2 1 short chain dehydrogenase RELT PF12606.8 KIK69243.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Epimerase PF01370.21 KIK69244.1 - 2.2e-18 66.6 0.2 3.5e-18 65.9 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK69244.1 - 4.4e-17 62.6 0.8 6.4e-17 62.0 0.8 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK69244.1 - 4.8e-15 55.3 0.0 6.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK69244.1 - 3.3e-13 49.4 0.6 1.3e-11 44.2 0.6 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIK69244.1 - 1.1e-09 38.2 0.8 2.5e-08 33.8 1.4 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIK69244.1 - 3.3e-07 30.0 0.1 4.3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK69244.1 - 3.9e-07 29.5 0.3 5.4e-07 29.0 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RELT PF12606.8 KIK69244.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 adh_short PF00106.25 KIK69244.1 - 0.021 14.3 0.4 0.38 10.2 0.1 2.2 1 1 1 2 2 2 0 short chain dehydrogenase 2-Hacid_dh PF00389.30 KIK69244.1 - 0.13 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Epimerase PF01370.21 KIK69245.1 - 1.6e-21 76.8 0.1 2.4e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK69245.1 - 1.2e-17 64.5 0.7 2e-17 63.7 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK69245.1 - 5.9e-17 61.6 0.0 7.7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK69245.1 - 8.6e-13 48.0 1.0 2.7e-11 43.1 1.0 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIK69245.1 - 7.7e-08 32.2 1.3 1.3e-06 28.2 1.5 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIK69245.1 - 9e-08 31.6 0.3 1.6e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK69245.1 - 1e-07 31.7 0.5 1.8e-07 30.9 0.4 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RELT PF12606.8 KIK69245.1 - 0.016 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 MDM31_MDM32 PF08118.11 KIK69246.1 - 2e-204 680.1 0.0 3.2e-204 679.5 0.0 1.3 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DnaJ PF00226.31 KIK69247.1 - 4.4e-15 55.6 0.5 1.1e-14 54.2 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain DUF3638 PF12340.8 KIK69250.1 - 2e-90 302.1 0.7 4e-90 301.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK69250.1 - 8.1e-17 60.3 0.2 1.7e-16 59.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PCRF PF03462.18 KIK69250.1 - 0.012 15.5 2.4 0.033 14.1 2.4 1.7 1 0 0 1 1 1 0 PCRF domain BAR PF03114.18 KIK69251.1 - 1.1e-49 169.3 1.5 1.3e-49 169.0 1.5 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KIK69251.1 - 0.00071 19.2 3.4 0.029 13.9 0.3 2.1 2 0 0 2 2 2 2 Arfaptin-like domain LPD39 PF18858.1 KIK69251.1 - 0.0083 16.2 5.5 0.14 12.2 0.8 2.7 3 0 0 3 3 3 2 Large polyvalent protein associated domain 39 EzrA PF06160.12 KIK69251.1 - 0.03 12.5 1.5 0.33 9.1 0.1 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SYF2 PF08231.12 KIK69251.1 - 0.046 14.1 6.1 0.12 12.8 6.0 1.9 1 1 0 1 1 1 0 SYF2 splicing factor BAR_3 PF16746.5 KIK69251.1 - 0.046 13.4 1.7 0.5 10.0 0.0 2.2 2 1 0 2 2 2 0 BAR domain of APPL family IFT57 PF10498.9 KIK69251.1 - 0.052 12.5 0.8 0.13 11.2 0.2 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 HrpF PF06266.12 KIK69251.1 - 0.053 13.8 0.3 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 HrpF protein Sec34 PF04136.15 KIK69251.1 - 0.32 10.9 2.3 0.3 11.0 0.2 2.0 2 0 0 2 2 2 0 Sec34-like family NACHT PF05729.12 KIK69252.1 - 9.3e-09 35.4 0.0 3.3e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK69252.1 - 1.1e-08 35.7 6.6 2.2e-08 34.7 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KIK69252.1 - 0.00032 20.7 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK69252.1 - 0.00041 20.6 0.1 0.0023 18.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KIK69252.1 - 0.00044 19.6 0.3 0.88 8.7 0.0 2.9 3 0 0 3 3 3 2 KAP family P-loop domain RNA_helicase PF00910.22 KIK69252.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK69252.1 - 0.014 16.0 0.2 0.3 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 KIK69253.1 - 0.046 13.6 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KIK69253.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain AMP-binding PF00501.28 KIK69254.1 - 1.1e-42 146.1 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIK69254.1 - 1.3e-05 25.0 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIK69254.1 - 0.0076 17.2 0.0 0.02 15.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C PF13193.6 KIK69255.1 - 0.0019 19.1 0.0 0.0031 18.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 KIK69258.1 - 2.3e-55 188.2 0.0 3.9e-55 187.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 KIK69259.1 - 5.4e-112 374.8 37.8 6.5e-112 374.6 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK69259.1 - 1.2e-24 86.9 39.8 1.5e-24 86.6 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease SWI-SNF_Ssr4 PF08549.10 KIK69260.1 - 3e-25 89.0 17.6 8.2e-19 67.7 0.1 3.0 2 1 1 3 3 3 3 Fungal domain of unknown function (DUF1750) Ax_dynein_light PF10211.9 KIK69260.1 - 0.15 12.0 3.5 0.26 11.2 3.5 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain MDH PF02315.16 KIK69260.1 - 0.19 11.8 2.2 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit DivIC PF04977.15 KIK69260.1 - 0.19 11.5 6.0 0.55 10.0 2.2 2.5 3 0 0 3 3 3 0 Septum formation initiator Atg14 PF10186.9 KIK69260.1 - 0.31 10.1 0.9 0.42 9.7 0.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MRPL52 PF18699.1 KIK69260.1 - 0.77 10.0 3.1 1.6 8.9 3.1 1.4 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Sporozoite_P67 PF05642.11 KIK69260.1 - 0.85 7.6 14.5 1.2 7.1 14.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box-like PF12937.7 KIK69261.1 - 1.8e-08 34.1 3.3 3.2e-08 33.3 0.8 2.6 2 0 0 2 2 2 1 F-box-like BRO1 PF03097.18 KIK69262.1 - 8.3e-34 117.0 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 KIK69262.1 - 0.0039 16.3 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5355) AA_permease_2 PF13520.6 KIK69263.1 - 5.5e-42 144.1 41.7 7.4e-42 143.6 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK69263.1 - 1.5e-23 83.2 33.8 2e-23 82.7 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF5480 PF17576.2 KIK69263.1 - 0.11 12.5 0.4 0.92 9.5 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5480) Corona_S2 PF01601.16 KIK69263.1 - 0.25 9.8 1.5 0.4 9.1 1.5 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein bZIP_2 PF07716.15 KIK69264.1 - 2.4e-10 40.3 15.8 2.8e-10 40.1 15.8 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK69264.1 - 0.00033 20.7 12.3 0.0011 19.0 12.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 KIK69264.1 - 0.0018 18.1 0.2 0.005 16.7 0.2 1.8 1 1 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.17 KIK69264.1 - 0.004 17.6 4.4 0.0047 17.4 4.4 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor TSC22 PF01166.18 KIK69264.1 - 0.01 16.1 1.5 0.016 15.5 1.5 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family Ax_dynein_light PF10211.9 KIK69264.1 - 0.028 14.4 2.0 0.03 14.3 2.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.12 KIK69264.1 - 0.05 13.7 5.5 0.056 13.5 5.5 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BRI3BP PF14965.6 KIK69264.1 - 0.13 11.8 0.7 0.13 11.7 0.7 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 NRBF2 PF08961.10 KIK69264.1 - 0.14 11.8 2.1 0.15 11.7 2.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator zf-C2H2 PF00096.26 KIK69265.1 - 3.1e-06 27.3 22.1 0.00078 19.8 1.6 3.4 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK69265.1 - 2.2e-05 24.6 2.4 0.12 12.7 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KIK69265.1 - 0.00017 21.6 7.5 0.015 15.3 1.5 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_4 PF13894.6 KIK69265.1 - 0.00022 21.8 11.6 0.0062 17.3 1.0 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK69265.1 - 0.0021 17.9 6.5 0.31 11.0 0.7 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KIK69265.1 - 0.0046 17.6 0.5 0.04 14.6 0.1 2.2 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KIK69265.1 - 0.013 15.9 2.0 2.3 8.7 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KIK69265.1 - 0.019 14.8 0.8 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_SprT PF17283.2 KIK69265.1 - 0.023 14.6 3.1 0.36 10.8 1.5 2.6 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 KIK69265.1 - 0.14 12.2 0.3 0.14 12.2 0.3 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KIK69265.1 - 0.29 10.8 4.3 0.57 9.8 0.7 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CCDC106 PF15794.5 KIK69265.1 - 2.8 7.6 6.0 0.33 10.6 1.6 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF629 PF04780.12 KIK69265.1 - 2.9 6.3 6.3 12 4.3 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) FYVE PF01363.21 KIK69265.1 - 6.8 6.9 9.1 82 3.4 7.6 2.3 1 1 1 2 2 2 0 FYVE zinc finger Metallophos PF00149.28 KIK69266.1 - 7.9e-36 124.5 0.3 9.7e-36 124.2 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK69266.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 KIK69266.1 - 0.14 12.6 0.6 0.29 11.6 0.6 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CRAL_TRIO PF00650.20 KIK69267.1 - 5.7e-14 52.1 0.0 8.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SET PF00856.28 KIK69268.1 - 8.7e-14 52.2 0.0 1.6e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KIK69268.1 - 2e-12 47.9 0.1 3.9e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KIK69269.1 - 1.1e-08 35.7 0.7 7.9e-08 32.9 0.2 2.5 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KIK69269.1 - 2.8e-05 24.5 16.6 2.8e-05 24.5 16.6 3.7 3 1 0 3 3 3 1 CXC domain adh_short PF00106.25 KIK69270.1 - 1.5e-36 125.7 0.1 2.1e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69270.1 - 1e-30 107.1 0.0 1.6e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69270.1 - 1.8e-05 24.7 1.0 0.00023 21.1 0.4 2.6 2 1 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KIK69270.1 - 0.0099 15.2 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Coprogen_oxidas PF01218.18 KIK69271.1 - 1.9e-129 430.6 0.0 2.2e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase AbiEi_3 PF11459.8 KIK69271.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system adh_short PF00106.25 KIK69272.1 - 2.5e-38 131.5 0.2 4.3e-38 130.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69272.1 - 1.2e-31 110.1 0.1 1.7e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69272.1 - 2e-06 27.9 0.1 1.6e-05 24.9 0.1 2.0 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KIK69272.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KIK69273.1 - 1.9e-53 181.4 0.3 2.6e-53 181.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK69273.1 - 4.8e-51 173.0 0.5 6.2e-51 172.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK69273.1 - 9.4e-09 35.4 0.3 1.6e-08 34.7 0.3 1.4 1 0 0 1 1 1 1 KR domain PhzC-PhzF PF02567.16 KIK69276.1 - 3.5e-40 138.2 0.0 4.2e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Gti1_Pac2 PF09729.9 KIK69278.1 - 3.5e-23 82.6 0.1 1.2e-19 71.1 0.1 2.1 2 0 0 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KIK69280.1 - 3.4e-29 102.2 0.8 1.3e-24 87.3 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family GAF_2 PF13185.6 KIK69281.1 - 4.9e-06 26.9 0.0 7.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KIK69281.1 - 0.0022 18.6 0.0 0.0033 18.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain GLTP PF08718.11 KIK69282.1 - 5.2e-45 153.4 0.0 6.7e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) LysM PF01476.20 KIK69283.1 - 1.8e-06 27.9 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 LysM domain ubiquitin PF00240.23 KIK69284.1 - 5.7e-14 51.6 0.0 9.3e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 KIK69284.1 - 1.1e-06 29.1 2.3 1.1e-06 29.1 2.3 1.6 1 1 1 2 2 2 1 Blt1 N-terminal domain Rad60-SLD PF11976.8 KIK69284.1 - 4e-05 23.4 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KIK69284.1 - 0.0092 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Voltage_CLC PF00654.20 KIK69286.1 - 5.3e-87 292.4 36.5 8.3e-87 291.7 36.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KIK69286.1 - 0.0062 17.0 0.1 0.2 12.1 0.1 2.7 2 0 0 2 2 2 1 CBS domain DUF924 PF06041.11 KIK69287.1 - 3.2e-25 89.3 0.0 4.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Transp_cyt_pur PF02133.15 KIK69287.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Septin PF00735.18 KIK69288.1 - 3.3e-107 358.0 0.5 4.5e-107 357.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIK69288.1 - 4.2e-07 30.0 0.0 1.1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK69288.1 - 0.00012 22.0 0.7 0.0016 18.3 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KIK69288.1 - 0.00042 20.4 2.6 0.47 10.5 0.0 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KIK69288.1 - 0.00091 18.8 0.3 0.067 12.7 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KIK69288.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK69288.1 - 0.034 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KIK69288.1 - 0.048 12.7 0.0 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KIK69288.1 - 0.06 12.7 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KIK69288.1 - 0.4 10.9 2.7 1.2 9.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain YdjM PF04307.14 KIK69289.1 - 0.01 15.2 3.1 0.011 15.1 3.1 1.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase ATP-synt_C PF00137.21 KIK69290.1 - 5.8e-24 84.2 33.3 3.9e-15 55.9 12.6 2.6 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 KIK69290.1 - 0.073 13.5 1.1 1 9.8 0.2 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 CUE PF02845.16 KIK69291.1 - 9.6e-10 38.0 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain YfhO PF09586.10 KIK69291.1 - 1.1 7.4 2.9 1.5 6.9 2.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PAT1 PF09770.9 KIK69291.1 - 8.4 4.5 19.4 13 3.9 19.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thaumatin PF00314.17 KIK69292.1 - 5.6e-65 219.0 15.4 6.3e-65 218.8 15.4 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK69292.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.3 1 1 0 1 1 1 1 Beta-1,3-glucanase Thaumatin PF00314.17 KIK69293.1 - 6.1e-69 231.9 16.1 8.2e-69 231.5 16.1 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK69293.1 - 6e-05 22.5 0.1 9.6e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Beta-1,3-glucanase PQQ PF01011.21 KIK69293.1 - 0.032 14.2 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat SET PF00856.28 KIK69294.1 - 5.7e-12 46.4 0.0 1.6e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Mistic PF11458.8 KIK69294.1 - 0.16 11.9 0.4 0.32 11.0 0.4 1.4 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Sugar_tr PF00083.24 KIK69296.1 - 9e-120 400.6 25.3 1e-119 400.4 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK69296.1 - 2.5e-17 62.9 41.0 6.5e-15 54.9 32.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KIK69297.1 - 2.6e-39 134.7 0.2 4e-39 134.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69297.1 - 2e-31 109.3 0.4 2.7e-31 108.9 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69297.1 - 1.1e-08 35.2 0.1 9e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.19 KIK69297.1 - 0.04 13.3 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KIK69298.1 - 1.9e-54 184.7 1.2 2.7e-54 184.2 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK69298.1 - 4.5e-53 179.6 0.9 5.5e-53 179.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK69298.1 - 4.3e-07 30.0 0.4 6.4e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK69298.1 - 0.0001 21.9 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KIK69299.1 - 6.2e-08 32.4 0.9 1.5e-07 31.2 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69299.1 - 7.8e-07 28.8 1.0 1.6e-06 27.8 1.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK69300.1 - 2.7e-07 30.4 0.3 8.1e-07 28.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69300.1 - 1.1e-06 28.3 0.1 2.6e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain LCD1 PF09798.9 KIK69301.1 - 0.13 10.8 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein ATP-synt_B PF00430.18 KIK69301.1 - 2.1 8.5 11.6 2.9 8.0 11.6 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TFIIA PF03153.13 KIK69302.1 - 4.5e-56 191.6 0.0 8.6e-38 131.4 0.1 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 KIK69303.1 - 7.6e-08 32.1 0.7 2.2e-07 30.7 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69303.1 - 4.4e-06 26.4 0.4 9.4e-06 25.4 0.4 1.5 1 0 0 1 1 1 1 F-box domain Glyco_hydro_18 PF00704.28 KIK69304.1 - 1.4e-61 208.9 0.8 1.7e-61 208.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.25 KIK69305.1 - 6.4e-52 175.9 1.4 8.4e-52 175.5 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69305.1 - 1.3e-48 165.7 1.5 1.8e-48 165.2 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69305.1 - 3.9e-09 36.7 0.3 5.5e-09 36.2 0.3 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK69305.1 - 0.044 13.1 0.1 0.85 8.9 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain INT_SG_DDX_CT_C PF15300.6 KIK69305.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus F-box-like PF12937.7 KIK69307.1 - 7.6e-08 32.1 0.2 2.1e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69307.1 - 9e-08 31.8 1.0 1.2e-07 31.4 0.1 1.7 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIK69307.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box adh_short PF00106.25 KIK69308.1 - 9.5e-52 175.3 0.3 1.1e-51 175.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69308.1 - 1.6e-49 168.6 0.1 2.2e-49 168.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69308.1 - 5.2e-08 33.0 0.1 7.5e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 KR domain F-box-like PF12937.7 KIK69309.1 - 1.9e-07 30.9 0.1 4.3e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69309.1 - 2.5e-07 30.4 0.1 1e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box PF00646.33 KIK69310.1 - 5.3e-07 29.4 0.6 1e-06 28.5 0.6 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK69310.1 - 1e-06 28.5 0.4 2.9e-06 27.1 0.4 1.8 2 0 0 2 2 2 1 F-box-like Thaumatin PF00314.17 KIK69312.1 - 8.2e-74 247.8 15.9 9.3e-74 247.7 15.9 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK69312.1 - 0.0092 15.3 3.7 0.012 14.9 0.1 2.5 2 1 0 2 2 2 1 Beta-1,3-glucanase Polyoma_lg_T_C PF06431.11 KIK69314.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus F-box-like PF12937.7 KIK69315.1 - 0.00041 20.2 0.5 0.0014 18.5 0.5 1.9 1 1 0 1 1 1 1 F-box-like GIT_SHD PF08518.11 KIK69320.1 - 7.9e-22 76.6 2.5 6.2e-12 44.9 1.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT SpecificRecomb PF10136.9 KIK69320.1 - 0.071 11.4 9.5 0.026 12.8 6.2 1.8 2 0 0 2 2 2 0 Site-specific recombinase Lebercilin PF15619.6 KIK69320.1 - 0.72 9.5 34.6 1.5 8.4 0.8 2.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin PF00261.20 KIK69320.1 - 0.79 9.0 32.0 3.7 6.9 19.4 2.4 1 1 1 2 2 2 0 Tropomyosin ANAPC15 PF15243.6 KIK69320.1 - 2.5 8.5 10.3 6.7 7.2 10.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Golgin_A5 PF09787.9 KIK69320.1 - 6.3 6.2 34.7 3.1 7.2 24.6 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 KIK69320.1 - 6.3 6.3 23.7 15 5.1 18.7 2.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit SpoVR PF04293.13 KIK69320.1 - 9.6 4.8 7.6 17 4.0 7.6 1.3 1 0 0 1 1 1 0 SpoVR like protein Ntox33 PF15533.6 KIK69323.1 - 0.096 13.2 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 Bacterial toxin 33 Ank_2 PF12796.7 KIK69324.1 - 4.8e-29 100.8 9.8 5.7e-13 49.3 0.8 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK69324.1 - 5.6e-28 97.0 2.6 2.4e-09 37.5 0.0 4.9 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KIK69324.1 - 7.1e-21 73.7 10.5 0.0091 16.4 0.0 6.6 6 1 1 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KIK69324.1 - 2e-20 70.7 4.4 0.02 15.4 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KIK69324.1 - 6.7e-10 39.0 5.0 0.0097 16.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF2064 PF09837.9 KIK69324.1 - 3.9e-05 23.5 1.9 1.2 9.0 0.0 3.7 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2064) DUF3789 PF12664.7 KIK69324.1 - 0.035 13.8 1.1 37 4.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3789) CholecysA-Rec_N PF09193.10 KIK69324.1 - 0.22 11.5 1.0 66 3.6 0.0 4.2 6 0 0 6 6 6 0 Cholecystokinin A receptor, N-terminal Cytochrom_C PF00034.21 KIK69326.1 - 0.14 13.3 0.0 0.25 12.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c PAP2_3 PF14378.6 KIK69326.1 - 0.15 11.8 0.2 0.23 11.1 0.2 1.2 1 0 0 1 1 1 0 PAP2 superfamily DUF4389 PF14333.6 KIK69327.1 - 0.0041 17.0 0.2 0.0091 15.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4389) DPM2 PF07297.12 KIK69327.1 - 0.075 13.3 1.8 0.83 10.0 0.1 2.4 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Cytochrom_C PF00034.21 KIK69328.1 - 0.082 14.1 0.0 0.085 14.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c DUF3328 PF11807.8 KIK69328.1 - 0.11 12.2 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) AMP-binding PF00501.28 KIK69329.1 - 3.1e-38 131.5 0.0 1.9e-37 128.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIK69329.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF2957 PF11170.8 KIK69329.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) DUF4235 PF14019.6 KIK69331.1 - 0.16 12.1 0.0 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) COX7a PF02238.15 KIK69332.1 - 2.2 8.8 0.0 2.2 8.8 0.0 3.3 5 0 0 5 5 5 0 Cytochrome c oxidase subunit VII COX7a PF02238.15 KIK69333.1 - 0.41 11.1 0.0 0.41 11.1 0.0 3.2 5 0 0 5 5 5 0 Cytochrome c oxidase subunit VII IMPDH PF00478.25 KIK69334.1 - 1e-127 425.9 1.2 6.2e-93 311.5 0.0 3.0 1 1 1 3 3 3 3 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KIK69334.1 - 6e-13 49.0 1.0 2.4e-05 24.7 0.0 3.2 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KIK69334.1 - 3.7e-10 39.4 0.2 1.2e-09 37.7 0.4 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KIK69334.1 - 3.4e-06 26.7 2.4 2.4e-05 23.9 2.4 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KIK69334.1 - 1.3e-05 24.8 6.7 3.7e-05 23.3 6.7 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KIK69334.1 - 0.00021 20.7 1.0 0.00051 19.4 1.0 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 KIK69334.1 - 0.0026 17.0 0.2 0.0055 15.9 0.2 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.19 KIK69334.1 - 0.014 14.8 0.5 0.1 12.0 0.1 2.5 3 0 0 3 3 3 0 KDPG and KHG aldolase Dus PF01207.17 KIK69334.1 - 0.033 13.3 1.8 1.4 7.9 0.2 2.2 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KIK69334.1 - 0.048 12.9 0.5 0.048 12.9 0.5 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KIK69334.1 - 0.058 12.8 1.2 0.89 8.9 0.2 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 KIK69334.1 - 0.076 12.2 0.6 0.14 11.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Glu_synthase PF01645.17 KIK69334.1 - 0.12 11.4 2.7 0.28 10.3 2.7 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase YpsA PF06908.11 KIK69334.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family IGPS PF00218.21 KIK69334.1 - 0.2 10.8 0.2 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Gti1_Pac2 PF09729.9 KIK69335.1 - 2.7e-28 99.3 1.1 9.6e-25 87.7 0.0 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family DUF3844 PF12955.7 KIK69336.1 - 4.3e-31 107.2 3.9 6.4e-31 106.6 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) MSA-2c PF12238.8 KIK69336.1 - 0.074 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c F-box-like PF12937.7 KIK69337.1 - 4.5e-07 29.6 0.8 9e-06 25.5 0.2 3.2 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KIK69337.1 - 0.0011 18.8 1.5 1.5 8.8 0.1 3.1 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.7 KIK69337.1 - 0.37 11.3 1.8 9.1 6.9 0.4 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Presenilin PF01080.17 KIK69339.1 - 0.8 8.4 1.9 0.91 8.2 1.9 1.0 1 0 0 1 1 1 0 Presenilin PhageMin_Tail PF10145.9 KIK69341.1 - 0.0013 18.7 0.2 0.0016 18.3 0.2 1.1 1 0 0 1 1 1 1 Phage-related minor tail protein COMPASS-Shg1 PF05205.12 KIK69341.1 - 0.0032 18.2 2.6 0.051 14.3 1.6 2.1 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 SKA1 PF07160.12 KIK69341.1 - 0.013 15.4 0.2 0.017 14.9 0.2 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 WYL_3 PF18488.1 KIK69341.1 - 0.076 13.4 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 WYL domain Gal4_dimer PF03902.13 KIK69342.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Gal4-like dimerisation domain Lebercilin PF15619.6 KIK69343.1 - 0.0065 16.2 2.6 0.82 9.3 0.0 2.1 1 1 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Pkinase PF00069.25 KIK69344.1 - 2e-11 43.8 0.4 1.7e-10 40.8 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69344.1 - 1.1e-06 28.1 0.0 0.00013 21.4 0.0 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK69344.1 - 0.0088 14.9 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ferritin_2 PF13668.6 KIK69345.1 - 1.6e-29 102.8 0.0 2.3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF1593 PF07632.11 KIK69346.1 - 1.1e-82 277.4 0.5 1.4e-82 277.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Lipase_GDSL_2 PF13472.6 KIK69346.1 - 0.044 14.2 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TPR_1 PF00515.28 KIK69347.1 - 2.5e-29 99.9 20.7 0.00017 21.2 0.1 9.9 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KIK69347.1 - 1e-24 86.8 28.5 7.4e-05 23.2 0.0 10.9 9 2 0 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK69347.1 - 5.8e-24 82.2 36.0 0.00087 19.2 0.6 13.0 15 0 0 15 15 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIK69347.1 - 6.6e-19 66.5 16.4 0.00085 19.4 0.3 11.9 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIK69347.1 - 7.2e-15 54.4 30.9 0.0011 19.6 0.2 13.2 8 4 6 14 14 13 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK69347.1 - 9.3e-15 55.0 28.2 0.0009 19.9 0.2 10.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KIK69347.1 - 3.4e-14 52.4 19.3 0.00012 22.5 0.2 9.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK69347.1 - 1.9e-13 50.5 27.9 1.5e-06 28.4 2.3 9.8 10 2 2 12 12 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK69347.1 - 3.2e-11 42.4 12.2 0.12 12.4 0.1 7.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK69347.1 - 4.3e-07 29.9 16.3 0.74 10.3 0.1 9.8 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK69347.1 - 6.1e-07 29.0 8.4 0.41 10.4 0.0 7.4 7 0 0 7 7 7 2 TPR repeat ANAPC3 PF12895.7 KIK69347.1 - 8.9e-05 22.6 12.7 0.063 13.5 0.1 6.2 5 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2989 PF11207.8 KIK69347.1 - 0.0036 17.1 12.5 0.033 13.9 0.2 5.0 4 2 2 6 6 6 1 Protein of unknown function (DUF2989) Molydop_binding PF01568.21 KIK69347.1 - 0.043 13.8 0.1 0.6 10.2 0.0 2.5 2 1 0 2 2 2 0 Molydopterin dinucleotide binding domain PknG_TPR PF16918.5 KIK69347.1 - 0.072 11.8 0.1 0.072 11.8 0.1 4.6 5 1 0 5 5 5 0 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 KIK69347.1 - 0.2 11.6 30.2 2.3 8.2 0.1 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat RXLR_WY PF18634.1 KIK69348.1 - 0.11 12.4 0.1 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain F-box-like PF12937.7 KIK69349.1 - 0.00029 20.6 7.4 0.00073 19.4 7.4 1.7 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK69350.1 - 3.9e-10 39.4 5.8 1e-09 38.1 5.8 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69350.1 - 0.00019 21.2 4.7 0.077 12.9 0.1 2.4 2 0 0 2 2 2 2 F-box domain DivIC PF04977.15 KIK69350.1 - 0.017 14.9 0.4 0.031 14.0 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator F_actin_bind PF08919.10 KIK69350.1 - 0.048 13.8 1.8 0.2 11.7 1.0 2.0 1 1 1 2 2 2 0 F-actin binding Csm1_N PF18504.1 KIK69350.1 - 0.056 13.8 0.5 0.093 13.1 0.5 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain Spc7 PF08317.11 KIK69350.1 - 0.066 12.1 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MFS_1 PF07690.16 KIK69351.1 - 2.1e-11 43.3 54.9 3.4e-08 32.8 52.8 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK69351.1 - 3.4e-05 22.5 11.6 3.4e-05 22.5 11.6 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) S1FA PF04689.13 KIK69351.1 - 0.15 12.2 0.1 0.42 10.8 0.1 1.8 1 0 0 1 1 1 0 DNA binding protein S1FA DUF3290 PF11694.8 KIK69351.1 - 7.3 6.6 7.2 0.46 10.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ank_4 PF13637.6 KIK69352.1 - 3e-15 56.4 0.5 9.3e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK69352.1 - 3.9e-13 49.8 0.5 6.1e-13 49.2 0.5 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK69352.1 - 3.1e-09 36.9 1.3 0.021 15.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK69352.1 - 9.3e-08 31.8 0.0 0.059 13.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat CD24 PF14984.6 KIK69352.1 - 0.16 12.2 0.7 4.7 7.5 0.1 2.2 2 0 0 2 2 2 0 CD24 protein ABC_tran PF00005.27 KIK69354.1 - 5.3e-46 156.5 0.0 6.7e-27 94.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK69354.1 - 3.5e-34 118.7 33.1 1.5e-22 80.5 12.2 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region DUF87 PF01935.17 KIK69354.1 - 4.7e-05 23.6 1.0 0.0016 18.6 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KIK69354.1 - 5.3e-05 23.5 2.0 0.018 15.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK69354.1 - 0.00033 20.3 0.9 0.52 10.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KIK69354.1 - 0.00063 19.2 5.5 0.58 9.5 2.6 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KIK69354.1 - 0.00075 19.7 1.6 2.7 8.3 0.0 3.8 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KIK69354.1 - 0.0016 18.9 0.1 0.57 10.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KIK69354.1 - 0.0044 16.5 0.5 1.5 8.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KIK69354.1 - 0.0059 16.7 0.2 2.9 8.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KIK69354.1 - 0.011 14.9 0.1 4.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIK69354.1 - 0.011 15.1 1.5 0.44 9.9 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KIK69354.1 - 0.017 15.7 0.2 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MWFE PF15879.5 KIK69354.1 - 0.019 15.1 0.7 6.5 7.0 0.1 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit AAA_21 PF13304.6 KIK69354.1 - 0.021 14.7 0.8 2.6 7.8 0.0 3.2 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIK69354.1 - 0.021 14.5 1.5 4.9 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KIK69354.1 - 0.039 14.3 0.1 8.4 6.8 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KIK69354.1 - 0.039 14.4 0.9 8.8 6.8 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIK69354.1 - 0.055 13.4 1.3 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KIK69354.1 - 0.06 12.5 0.1 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KIK69354.1 - 0.17 11.9 0.5 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Adeno_IVa2 PF02456.15 KIK69354.1 - 0.19 10.5 0.3 0.45 9.2 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.6 KIK69354.1 - 0.2 12.2 0.1 4.7 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK69354.1 - 0.23 11.0 1.8 0.52 9.9 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIK69354.1 - 0.31 11.2 3.5 0.37 11.0 0.1 2.5 3 0 0 3 3 2 0 AAA domain Acetyltransf_8 PF13523.6 KIK69355.1 - 7.6e-30 103.5 0.1 1.2e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 KIK69356.1 - 2.9e-47 161.1 0.0 3.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK69356.1 - 6.3e-24 85.1 0.1 3.1e-23 82.8 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase F-box PF00646.33 KIK69357.1 - 4.1e-07 29.7 0.2 1.4e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK69357.1 - 1.2e-06 28.3 1.5 2.6e-06 27.2 0.6 2.1 2 0 0 2 2 2 1 F-box-like BBS2_N PF14781.6 KIK69357.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Aldo_ket_red PF00248.21 KIK69358.1 - 6.2e-49 166.8 0.0 7e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ESCRT-II PF05871.12 KIK69358.1 - 0.067 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit K_oxygenase PF13434.6 KIK69359.1 - 5.1e-94 315.2 0.0 6.3e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK69359.1 - 3.1e-06 27.3 0.2 0.00013 22.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK69359.1 - 3.2e-05 24.4 0.0 0.54 10.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK69359.1 - 0.00014 21.2 0.0 1.6 7.9 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK69359.1 - 0.00026 20.3 0.0 0.0019 17.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK69359.1 - 0.13 11.9 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AMP-binding PF00501.28 KIK69360.1 - 7.9e-70 235.6 0.0 1.1e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2204 PF09970.9 KIK69360.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) OHCU_decarbox PF09349.10 KIK69361.1 - 0.0014 19.1 0.1 0.0018 18.8 0.1 1.2 1 0 0 1 1 1 1 OHCU decarboxylase AMP-binding_C PF13193.6 KIK69361.1 - 0.0019 19.1 0.0 0.0034 18.3 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1173 PF06666.11 KIK69361.1 - 0.072 12.0 0.1 0.092 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Abhydrolase_6 PF12697.7 KIK69362.1 - 1.1e-07 32.7 0.2 1.3e-07 32.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KIK69362.1 - 0.0084 15.2 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 KIK69363.1 - 1.7e-09 38.6 0.2 2e-09 38.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KIK69363.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK69363.1 - 0.017 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase CcmH PF03918.14 KIK69363.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein F-box-like PF12937.7 KIK69365.1 - 2.1e-06 27.5 1.1 2.1e-06 27.5 1.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK69365.1 - 0.038 13.9 1.7 6.4 6.8 0.3 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK69367.1 - 1.2e-07 31.5 1.3 9.4e-07 28.6 0.2 2.8 3 0 0 3 3 3 1 F-box-like GPS2_interact PF15784.5 KIK69367.1 - 0.042 14.3 0.1 0.07 13.6 0.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain F-box PF00646.33 KIK69367.1 - 7.2 6.6 9.8 20 5.2 2.2 3.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK69368.1 - 2.3e-08 33.8 1.9 9.7e-08 31.8 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK69369.1 - 2.3e-07 30.6 3.0 5.4e-07 29.4 3.0 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69369.1 - 0.0027 17.5 5.9 0.55 10.2 0.1 2.5 2 0 0 2 2 2 2 F-box domain Vac_Fusion PF02346.16 KIK69369.1 - 0.065 12.9 0.5 0.14 11.9 0.5 1.5 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 GPS2_interact PF15784.5 KIK69369.1 - 0.098 13.1 0.4 0.2 12.1 0.4 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Ferritin_2 PF13668.6 KIK69370.1 - 9.1e-35 119.8 5.4 1.3e-34 119.3 5.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ub-Mut7C PF14451.6 KIK69370.1 - 0.015 15.1 0.0 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Mut7-C ubiquitin STD1 PF17235.2 KIK69370.1 - 0.022 14.4 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 STD1/MTH1 SR-25 PF10500.9 KIK69370.1 - 1.5 8.4 15.2 2.5 7.7 15.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 KIK69370.1 - 1.5 7.1 11.4 2.6 6.3 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MMR_HSR1 PF01926.23 KIK69371.1 - 1.1e-09 38.3 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK69371.1 - 9.1e-05 21.9 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIK69371.1 - 0.00069 20.1 0.0 0.0008 19.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK69371.1 - 0.00077 19.7 0.0 0.0026 17.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIK69371.1 - 0.00081 19.5 0.3 0.0032 17.5 0.2 1.8 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK69371.1 - 0.0011 18.9 0.1 0.0027 17.7 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KIK69371.1 - 0.0041 16.7 0.0 0.0067 16.0 0.0 1.6 1 1 0 1 1 1 1 Ras family DUF815 PF05673.13 KIK69371.1 - 0.0058 15.8 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KIK69371.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 KIK69371.1 - 0.0096 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 KIK69371.1 - 0.014 14.9 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KIK69371.1 - 0.014 15.8 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK69371.1 - 0.042 14.1 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK69371.1 - 0.064 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.10 KIK69371.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.21 KIK69371.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase Septin PF00735.18 KIK69371.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 KIK69371.1 - 0.18 12.3 0.2 0.29 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KIK69371.1 - 0.19 10.7 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FUSC_2 PF13515.6 KIK69372.1 - 3.8e-19 69.0 12.7 3.8e-19 69.0 12.7 3.1 4 0 0 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.8 KIK69372.1 - 5.7e-11 41.9 7.1 3.7e-10 39.3 6.6 2.3 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.12 KIK69372.1 - 3.8e-09 35.7 17.0 9.5e-08 31.0 8.2 2.8 3 0 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 KIK69372.1 - 1e-08 35.3 0.0 4.9e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 KIK69372.1 - 0.1 11.6 8.2 0.21 10.6 0.9 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS EF-hand_7 PF13499.6 KIK69373.1 - 1.2e-12 48.1 2.0 2.5e-05 24.6 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK69373.1 - 2.9e-12 45.4 2.0 1.5e-05 24.5 0.2 3.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KIK69373.1 - 7.4e-09 34.5 4.7 0.00086 18.7 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KIK69373.1 - 0.0015 17.9 0.9 0.17 11.5 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 KIK69373.1 - 0.0029 17.9 0.1 1.6 9.1 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain DUF2666 PF10869.8 KIK69373.1 - 0.021 15.1 0.0 1.3 9.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) UPF0154 PF03672.13 KIK69373.1 - 0.035 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Fe-S_assembly PF04384.13 KIK69373.1 - 0.086 13.5 0.1 0.24 12.0 0.0 1.8 1 1 0 1 1 1 0 Iron-sulphur cluster assembly DUF1456 PF07308.13 KIK69373.1 - 0.13 12.6 0.0 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) API5 PF05918.11 KIK69374.1 - 6.6e-23 81.3 0.2 9.2e-23 80.8 0.2 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KIK69374.1 - 2.3e-05 24.7 0.0 7.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats Cytochrom_B561 PF03188.16 KIK69377.1 - 8.1e-12 45.5 4.1 1.2e-08 35.2 0.5 2.2 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KIK69377.1 - 2.7e-07 30.5 1.9 5.3e-07 29.5 0.7 2.1 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Ytp1 PF10355.9 KIK69377.1 - 0.0075 15.5 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) COX7C PF02935.16 KIK69377.1 - 0.0083 16.4 0.5 0.031 14.5 0.5 2.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF4079 PF13301.6 KIK69377.1 - 0.03 14.5 1.5 1.3 9.2 1.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF973 PF06157.11 KIK69377.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) ATF7IP_BD PF16788.5 KIK69377.1 - 0.17 11.9 1.9 0.28 11.2 1.9 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF1206 PF06724.11 KIK69377.1 - 0.63 10.2 5.2 7.3 6.7 2.0 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) S-methyl_trans PF02574.16 KIK69378.1 - 3e-55 187.9 0.0 3.7e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pkinase PF00069.25 KIK69379.1 - 6.4e-66 222.4 0.0 8.2e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69379.1 - 2.3e-33 115.6 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIK69379.1 - 3.3e-17 62.6 0.1 8.2e-17 61.3 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KIK69379.1 - 1.1e-06 28.3 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK69379.1 - 1.7e-05 24.3 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK69379.1 - 0.00089 18.3 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK69379.1 - 0.003 17.5 0.0 0.04 13.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK69379.1 - 0.0064 15.3 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Zn_clus PF00172.18 KIK69380.1 - 0.00045 20.3 6.3 0.00083 19.4 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyltransferase PF01553.21 KIK69381.1 - 6.8e-17 61.4 0.0 1.1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PyrBI_leader PF08052.11 KIK69381.1 - 0.98 9.4 3.1 2.5 8.1 3.1 1.6 1 0 0 1 1 1 0 PyrBI operon leader peptide MCPVI PF02993.14 KIK69381.1 - 4.1 7.2 7.1 6.6 6.5 7.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI F-box-like PF12937.7 KIK69382.1 - 6.8e-11 41.9 2.7 1.4e-10 40.8 2.7 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69382.1 - 0.0023 17.8 5.3 0.018 14.9 5.3 2.2 1 1 0 1 1 1 1 F-box domain Sec10 PF07393.11 KIK69382.1 - 0.069 11.6 0.1 0.079 11.4 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 F-box-like PF12937.7 KIK69383.1 - 2.7e-10 40.0 4.1 8.9e-10 38.3 1.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK69383.1 - 4.4 7.3 10.7 0.69 9.9 4.9 2.8 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIK69385.1 - 2.6e-07 30.4 5.7 9.5e-07 28.6 5.7 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69385.1 - 0.002 18.0 4.2 0.018 14.9 4.2 2.5 1 1 0 1 1 1 1 F-box domain MscS_porin PF12795.7 KIK69385.1 - 0.026 14.1 1.5 0.044 13.3 1.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Dynactin_p22 PF07426.11 KIK69385.1 - 0.034 14.0 0.5 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 Dynactin subunit p22 FliJ PF02050.16 KIK69385.1 - 0.043 14.0 0.1 0.078 13.2 0.1 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Dynactin_p22 PF07426.11 KIK69386.1 - 0.00085 19.2 2.3 0.015 15.1 0.1 2.9 3 0 0 3 3 3 1 Dynactin subunit p22 F-box-like PF12937.7 KIK69386.1 - 0.0011 18.8 0.1 0.01 15.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like DivIVA PF05103.13 KIK69386.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 DivIVA protein MscS_porin PF12795.7 KIK69386.1 - 0.04 13.4 0.1 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Snf7 PF03357.21 KIK69387.1 - 1e-34 119.6 7.5 1e-34 119.6 7.5 1.7 2 0 0 2 2 2 1 Snf7 CAF1-p150_C2 PF15539.6 KIK69387.1 - 0.054 13.0 0.2 0.065 12.7 0.2 1.1 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term F-box-like PF12937.7 KIK69388.1 - 8.9e-08 31.9 7.1 2.7e-07 30.4 7.1 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69388.1 - 0.0025 17.6 7.0 0.43 10.5 0.2 2.5 2 0 0 2 2 2 2 F-box domain F-box-like_2 PF13013.6 KIK69388.1 - 0.17 11.8 4.3 5.4 7.0 0.7 2.6 1 1 1 2 2 2 0 F-box-like domain Ribosomal_S2 PF00318.20 KIK69389.1 - 3.6e-30 104.8 0.2 2.4e-15 56.4 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KIK69389.1 - 1e-10 42.8 7.5 1.9e-10 42.0 7.5 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus CENP-B_dimeris PF09026.10 KIK69390.1 - 0.069 13.5 3.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase_Tyr PF07714.17 KIK69391.1 - 8.5e-42 143.2 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK69391.1 - 7.3e-32 110.8 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK69391.1 - 0.016 15.1 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATG13 PF10033.9 KIK69391.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 RIO1 PF01163.22 KIK69391.1 - 0.18 11.4 0.0 0.49 10.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 KIK69392.1 - 2.8e-41 141.5 0.0 4.1e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK69392.1 - 4.1e-34 118.1 0.0 6.2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK69392.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK69392.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Solute_trans_a PF03619.16 KIK69393.1 - 0.091 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha F-box-like PF12937.7 KIK69394.1 - 4.2e-10 39.4 1.8 5.7e-10 38.9 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK69394.1 - 0.00011 22.0 2.9 0.00055 19.7 2.9 2.1 1 1 0 1 1 1 1 F-box domain Beta-prism_lec PF16458.5 KIK69395.1 - 0.00037 20.5 0.1 0.00055 19.9 0.1 1.2 1 0 0 1 1 1 1 Beta-prism lectin Jacalin PF01419.17 KIK69395.1 - 0.027 14.4 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Jacalin-like lectin domain DUF2644 PF10841.8 KIK69397.1 - 0.062 13.5 0.2 0.1 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Csm1_N PF18504.1 KIK69398.1 - 0.042 14.2 0.1 0.055 13.8 0.1 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain F-box-like PF12937.7 KIK69398.1 - 0.05 13.5 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 F-box-like JHY PF15261.6 KIK69398.1 - 0.1 13.3 0.0 0.11 13.2 0.0 1.1 1 0 0 1 1 1 0 Jhy protein Beta-prism_lec PF16458.5 KIK69399.1 - 0.00091 19.2 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Beta-prism lectin F-box-like PF12937.7 KIK69400.1 - 5.2e-09 35.9 2.5 8.5e-09 35.2 0.9 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK69400.1 - 0.021 14.7 5.8 0.21 11.5 5.8 2.5 1 1 0 1 1 1 0 F-box domain MscS_porin PF12795.7 KIK69400.1 - 0.057 13.0 1.1 0.086 12.4 1.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Retrotrans_gag PF03732.17 KIK69402.1 - 2.2e-06 27.9 0.6 4.5e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK69402.1 - 3.8e-05 23.5 4.0 0.00012 21.9 4.0 1.9 1 0 0 1 1 1 1 Zinc knuckle Arrestin_N PF00339.29 KIK69402.1 - 0.046 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain zf-CCHC_2 PF13696.6 KIK69402.1 - 1.5 8.7 7.5 0.19 11.6 2.8 1.9 2 0 0 2 2 2 0 Zinc knuckle IL11 PF07400.11 KIK69403.1 - 0.045 13.4 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Interleukin 11 PLU-1 PF08429.11 KIK69403.1 - 0.084 12.0 0.1 0.089 12.0 0.1 1.1 1 0 0 1 1 1 0 PLU-1-like protein DNA_pol_A_exo1 PF01612.20 KIK69404.1 - 3.4e-16 59.5 0.1 7.2e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Plavaka PF18759.1 KIK69406.1 - 1.7e-37 129.4 0.1 4.5e-37 128.0 0.0 1.7 2 0 0 2 2 2 1 Plavaka transposase PLU-1 PF08429.11 KIK69409.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 PLU-1-like protein PI_PP_C PF18365.1 KIK69409.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain PRMT5 PF05185.16 KIK69410.1 - 0.051 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Varsurf_PPLC PF03490.13 KIK69412.1 - 0.039 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Peptidase_U4 PF03419.13 KIK69413.1 - 0.18 11.1 0.4 0.65 9.2 0.1 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TPR_10 PF13374.6 KIK69414.1 - 2.7e-110 357.7 0.0 9.8e-09 34.8 0.0 13.5 14 0 0 14 14 13 13 Tetratricopeptide repeat TPR_12 PF13424.6 KIK69414.1 - 5e-91 299.1 8.3 5.9e-14 52.1 0.1 12.2 3 3 9 12 12 12 11 Tetratricopeptide repeat TPR_1 PF00515.28 KIK69414.1 - 3.7e-26 89.8 31.1 0.08 12.8 0.2 12.5 13 0 0 13 13 12 8 Tetratricopeptide repeat TPR_8 PF13181.6 KIK69414.1 - 1.2e-23 81.3 17.0 0.22 11.9 0.0 12.5 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK69414.1 - 4.9e-20 70.0 19.6 0.16 12.1 0.0 12.5 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK69414.1 - 5e-18 63.7 26.8 0.29 11.3 0.0 11.9 12 0 0 12 12 12 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK69414.1 - 1e-12 48.1 0.1 1.1 9.6 0.1 8.1 5 2 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KIK69414.1 - 6.5e-10 38.7 0.0 14 6.7 0.1 8.0 9 0 0 9 9 7 0 Tetratricopeptide repeat PPR PF01535.20 KIK69414.1 - 2.6e-08 33.6 3.5 13 6.3 0.0 9.3 10 0 0 10 10 10 0 PPR repeat TPR_19 PF14559.6 KIK69414.1 - 4.3e-08 33.5 9.1 11 6.6 0.0 8.9 5 4 5 10 10 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK69414.1 - 4.6e-07 29.9 0.1 0.28 11.3 0.0 6.1 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK69414.1 - 3.8e-06 27.2 11.7 82 4.2 0.2 10.2 10 1 0 10 10 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK69414.1 - 9.6e-06 26.0 2.6 16 6.6 0.0 8.1 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK69414.1 - 1.1e-05 25.9 2.2 1.1e+02 3.6 0.0 8.7 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK69414.1 - 1.9e-05 24.7 27.0 3.1 8.4 0.0 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat Titin_Ig-rpts PF06582.12 KIK69414.1 - 2.2e-05 24.3 4.6 5.5 7.0 0.0 6.7 7 0 0 7 7 7 1 Titin repeat TPR_MalT PF17874.1 KIK69414.1 - 0.00017 21.1 2.6 0.17 11.2 1.5 3.3 4 0 0 4 4 4 2 MalT-like TPR region DUF3856 PF12968.7 KIK69414.1 - 0.0037 17.3 0.2 1.7 8.7 0.0 4.5 4 3 1 6 6 6 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 KIK69414.1 - 0.0054 16.8 3.8 5.7 7.1 0.0 4.6 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain Paf67 PF10255.9 KIK69414.1 - 0.012 14.6 0.0 0.34 9.9 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 DUF2225 PF09986.9 KIK69414.1 - 0.023 14.4 0.1 1.2 8.8 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 KIK69414.1 - 0.32 11.4 1.2 45 4.5 0.1 4.0 4 1 1 5 5 4 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 KIK69414.1 - 0.52 10.4 18.1 2.5 8.2 0.2 6.6 9 0 0 9 9 8 0 Tetratricopeptide repeat DIM1 PF02966.16 KIK69415.1 - 6.2e-69 229.9 0.0 7e-69 229.7 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KIK69415.1 - 3.7e-05 23.6 0.1 4.9e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIK69415.1 - 0.011 16.0 0.3 0.017 15.5 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like UvdE PF03851.14 KIK69416.1 - 2.8e-84 282.6 0.0 3.5e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE SKA1 PF07160.12 KIK69416.1 - 3.1 7.6 5.0 0.41 10.4 0.7 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 S-antigen PF05756.11 KIK69416.1 - 6.9 7.1 7.1 0.32 11.4 1.4 1.8 2 0 0 2 2 2 0 S-antigen protein Condensation PF00668.20 KIK69417.1 - 1.9e-169 564.2 0.0 2.3e-38 132.0 0.0 5.9 5 1 0 5 5 5 5 Condensation domain AMP-binding PF00501.28 KIK69417.1 - 5.3e-155 516.2 0.0 6e-67 226.1 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KIK69417.1 - 1.5e-47 159.8 3.0 1.7e-09 37.9 0.4 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIK69417.1 - 1.5e-09 38.7 0.5 0.0022 18.9 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KIK69417.1 - 0.24 10.0 0.5 7.3 5.1 0.0 3.1 4 0 0 4 4 4 0 Transferase family RINGv PF12906.7 KIK69418.1 - 0.00066 19.7 6.6 0.0011 19.0 6.6 1.4 1 0 0 1 1 1 1 RING-variant domain MLANA PF14991.6 KIK69418.1 - 0.0091 16.3 0.3 0.19 12.0 0.0 2.3 2 0 0 2 2 2 1 Protein melan-A zf-RING_2 PF13639.6 KIK69418.1 - 0.061 13.7 10.8 0.063 13.6 7.5 2.2 2 0 0 2 2 2 0 Ring finger domain MacB_PCD PF12704.7 KIK69418.1 - 0.069 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain PHD_4 PF16866.5 KIK69418.1 - 1.4 9.1 4.8 2.8 8.1 4.8 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KIK69418.1 - 1.8 8.2 6.2 3.1 7.5 4.3 2.2 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Abhydrolase_6 PF12697.7 KIK69419.1 - 4.2e-06 27.5 0.1 5.2e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KIK69420.1 - 3e-06 28.0 0.0 3.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KIK69420.1 - 0.0026 16.8 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KIK69420.1 - 0.0038 16.2 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Glutaminase PF04960.15 KIK69420.1 - 0.25 10.5 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 Glutaminase Abhydrolase_6 PF12697.7 KIK69422.1 - 2.6e-07 31.5 0.1 3e-07 31.3 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KIK69424.1 - 1.4e-08 35.6 0.1 1.7e-08 35.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KIK69425.1 - 0.016 15.9 0.1 0.019 15.6 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family SPA PF08616.10 KIK69427.1 - 1.4e-33 115.3 0.0 2.8e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KIK69427.1 - 3.4e-17 63.2 0.9 4.4e-14 53.1 0.9 2.5 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KIK69427.1 - 0.0032 16.2 0.0 2.1 7.0 0.0 3.0 3 1 0 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 KIK69427.1 - 0.11 12.0 0.0 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Isochorismatase PF00857.20 KIK69429.1 - 2.1e-15 57.3 0.3 2.1e-14 54.1 0.3 2.1 1 1 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.18 KIK69431.1 - 4.8e-07 29.8 12.3 1e-06 28.8 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK69431.1 - 9.2e-06 24.9 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.23 KIK69432.1 - 5e-13 49.1 0.1 1.1e-12 48.0 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KIK69432.1 - 0.00049 20.1 2.9 0.024 14.7 0.2 2.7 2 0 0 2 2 2 2 GRF zinc finger UIM PF02809.20 KIK69432.1 - 0.0043 16.9 0.4 0.0089 15.9 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Spuma_A9PTase PF03539.14 KIK69432.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Nucleo_P87 PF07267.11 KIK69432.1 - 0.52 9.1 7.8 0.75 8.6 7.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CFEM PF05730.11 KIK69433.1 - 4.2e-10 39.6 15.3 7.4e-10 38.8 15.3 1.4 1 0 0 1 1 1 1 CFEM domain Hepar_II_III PF07940.13 KIK69434.1 - 1.7e-10 40.9 1.3 3.1e-10 40.1 1.3 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 KIK69434.1 - 3.7e-05 22.4 3.6 6.8e-05 21.6 3.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) Abhydrolase_6 PF12697.7 KIK69440.1 - 0.00019 22.1 0.0 0.00025 21.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KIK69441.1 - 7.6e-11 43.0 0.0 1.2e-10 42.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Retrotrans_gag PF03732.17 KIK69442.1 - 1.5e-08 34.8 1.5 2.2e-08 34.3 1.5 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Abhydrolase_6 PF12697.7 KIK69443.1 - 7.1e-06 26.8 0.0 8.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Asp PF00026.23 KIK69444.1 - 7.8e-64 216.1 5.7 7.8e-64 216.1 5.7 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK69444.1 - 2.1e-11 44.4 3.1 2.1e-11 44.4 3.1 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK69444.1 - 0.17 12.6 9.0 0.064 13.9 1.2 3.5 3 1 0 3 3 3 0 Aspartyl protease Asp PF00026.23 KIK69445.1 - 1.2e-60 205.6 1.8 2.2e-60 204.7 1.8 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK69445.1 - 3.9e-08 33.7 15.6 5.7e-08 33.2 0.1 3.2 5 0 0 5 5 5 2 Xylanase inhibitor N-terminal F-box-like PF12937.7 KIK69446.1 - 0.0029 17.5 1.7 0.0065 16.3 0.4 2.2 2 0 0 2 2 2 1 F-box-like CAP_GLY PF01302.25 KIK69448.1 - 2.5e-16 59.5 0.0 4.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Golgin_A5 PF09787.9 KIK69448.1 - 0.0089 15.5 2.7 0.0089 15.5 2.7 5.1 2 1 3 5 5 5 3 Golgin subfamily A member 5 DUF1664 PF07889.12 KIK69448.1 - 0.017 15.1 32.3 0.17 12.0 0.5 6.2 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KIK69448.1 - 0.046 14.1 0.4 0.046 14.1 0.4 9.5 9 4 3 12 12 12 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KIK69448.1 - 0.65 8.8 74.8 0.19 10.6 17.1 5.9 2 1 3 6 6 6 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KIK69448.1 - 3.3 7.5 29.5 0.84 9.4 4.0 4.9 5 1 0 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) CLIP1_ZNF PF16641.5 KIK69448.1 - 4.4 7.3 17.1 0.62 10.0 0.8 2.7 3 0 0 3 3 3 0 CLIP1 zinc knuckle adh_short PF00106.25 KIK69449.1 - 1e-30 106.7 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69449.1 - 3.9e-14 52.8 0.0 5.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69449.1 - 1.7e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK69449.1 - 0.00097 18.7 0.0 0.0014 18.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KIK69449.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.15 KIK69449.1 - 0.025 14.4 0.2 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 KIK69449.1 - 0.031 14.2 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KIK69449.1 - 0.046 13.6 0.1 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding PALP PF00291.25 KIK69449.1 - 0.068 12.6 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ApbA PF02558.16 KIK69449.1 - 0.075 12.7 0.2 0.21 11.2 0.1 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.8 KIK69449.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox PF00070.27 KIK69449.1 - 0.1 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 KIK69449.1 - 0.14 11.2 0.0 0.56 9.2 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIK69449.1 - 0.15 11.4 0.0 0.41 10.0 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIK69449.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family TRAP_alpha PF03896.16 KIK69449.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit WD40 PF00400.32 KIK69451.1 - 5.5e-55 182.1 39.6 8.3e-07 29.6 0.7 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat AAA_16 PF13191.6 KIK69451.1 - 2e-09 38.1 0.0 6e-09 36.5 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 KIK69451.1 - 1.5e-08 34.8 0.0 3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KIK69451.1 - 7.6e-06 26.1 11.3 5.3 7.4 0.0 7.8 2 1 7 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KIK69451.1 - 7.4e-05 23.0 0.0 0.00031 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK69451.1 - 0.00013 22.0 0.0 0.0058 16.6 0.0 2.6 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KIK69451.1 - 0.00057 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 NTPase Nup160 PF11715.8 KIK69451.1 - 0.0013 17.4 14.0 1 7.9 0.1 5.8 2 2 6 8 8 8 2 Nucleoporin Nup120/160 RNA_helicase PF00910.22 KIK69451.1 - 0.0021 18.4 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 KIK69451.1 - 0.0023 17.3 0.0 0.0068 15.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein AAA_5 PF07728.14 KIK69451.1 - 0.0033 17.4 0.0 0.0099 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIK69451.1 - 0.0086 15.6 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KIK69451.1 - 0.011 16.2 0.0 0.032 14.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK69451.1 - 0.023 13.9 0.0 0.053 12.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KIK69451.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 KIK69451.1 - 0.05 13.7 0.0 1.7 8.7 0.0 2.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK69451.1 - 0.086 12.5 0.0 0.52 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KIK69451.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1349 PF07081.11 KIK69452.1 - 7.2e-23 81.2 0.0 9.2e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) RNase_T PF00929.24 KIK69455.1 - 0.00065 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KIK69455.1 - 0.3 11.3 2.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 ElonginA binding-protein 1 PhzC-PhzF PF02567.16 KIK69456.1 - 3.5e-37 128.4 0.0 4.3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein gag_pre-integrs PF13976.6 KIK69458.1 - 7.4e-05 22.5 0.1 9.8e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain G-alpha PF00503.20 KIK69461.1 - 7.2e-97 324.7 0.0 9.1e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK69461.1 - 1e-10 41.4 0.1 4.3e-06 26.3 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK69461.1 - 0.00052 20.1 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK69461.1 - 0.012 15.2 0.0 1.6 8.3 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KIK69461.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK69461.1 - 0.13 12.2 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 KIK69461.1 - 0.13 11.6 0.1 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 KIK69461.1 - 0.18 12.0 0.2 1.9 8.7 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 KIK69464.1 - 5.6e-59 194.7 35.3 2.7e-08 34.3 0.4 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK69464.1 - 4.7e-10 39.6 4.2 0.097 13.0 0.0 7.1 4 2 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KIK69464.1 - 2e-06 28.3 0.0 5.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK69464.1 - 0.00016 21.6 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK69464.1 - 0.0022 18.3 0.5 0.02 15.3 0.0 2.9 3 0 0 3 3 3 1 RNA helicase WD40_like PF17005.5 KIK69464.1 - 0.0027 17.1 0.7 0.51 9.6 0.1 3.1 2 1 1 3 3 3 2 WD40-like domain ATPase_2 PF01637.18 KIK69464.1 - 0.0061 16.5 0.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Ge1_WD40 PF16529.5 KIK69464.1 - 0.015 14.2 1.1 1.1 8.1 0.0 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_18 PF13238.6 KIK69464.1 - 0.066 13.8 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KIK69464.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK69464.1 - 0.19 12.0 0.0 0.72 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KIK69465.1 - 5.7e-37 127.5 44.1 4.7e-25 88.3 20.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KIK69465.1 - 4.2e-08 32.1 22.5 6.7e-08 31.4 22.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.6 KIK69465.1 - 0.42 10.5 15.9 0.068 13.1 1.2 4.0 4 0 0 4 4 4 0 YrhK-like protein DUF4212 PF13937.6 KIK69465.1 - 5.9 7.3 7.9 2.2 8.7 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) WD40 PF00400.32 KIK69466.1 - 1.9e-46 155.1 42.4 2.8e-06 28.0 1.1 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK69466.1 - 7.8e-11 42.1 11.0 0.48 10.8 0.1 7.8 3 3 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KIK69466.1 - 1.2e-09 38.8 0.0 2.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK69466.1 - 6e-09 36.0 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK69466.1 - 4.7e-05 23.4 0.1 0.12 12.2 0.0 3.2 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KIK69466.1 - 0.00024 21.1 0.0 0.00075 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KIK69466.1 - 0.00066 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KIK69466.1 - 0.0019 18.5 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain HARP PF07443.13 KIK69466.1 - 0.007 16.0 0.4 1.3 8.7 0.0 4.4 6 0 0 6 6 5 1 HepA-related protein (HARP) PHTB1_N PF14727.6 KIK69466.1 - 0.0079 15.6 1.6 3.2 7.0 0.1 3.3 3 1 0 3 3 3 1 PTHB1 N-terminus PALB2_WD40 PF16756.5 KIK69466.1 - 0.0085 15.1 9.3 2.6 6.9 0.0 4.5 3 3 3 6 6 6 3 Partner and localizer of BRCA2 WD40 domain RNA_helicase PF00910.22 KIK69466.1 - 0.0088 16.4 0.0 0.034 14.5 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KIK69466.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.14 KIK69466.1 - 0.022 14.0 0.3 0.78 8.9 0.1 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 KIK69466.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region APS_kinase PF01583.20 KIK69466.1 - 0.039 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK69466.1 - 0.044 13.0 0.0 0.096 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KIK69466.1 - 0.052 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA PF00004.29 KIK69466.1 - 0.061 13.8 0.0 0.19 12.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KIK69466.1 - 0.14 12.2 0.1 0.51 10.4 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.6 KIK69466.1 - 0.15 12.1 0.2 2.6 8.1 0.2 2.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK69466.1 - 0.17 12.4 0.1 0.55 10.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK69466.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MtN3_slv PF03083.16 KIK69467.1 - 0.03 14.4 2.2 0.035 14.1 1.4 1.5 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange MtN3_slv PF03083.16 KIK69468.1 - 2.8 8.1 9.6 0.43 10.7 1.2 2.8 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Sensor PF13796.6 KIK69469.1 - 6e-06 26.4 13.0 0.011 15.8 3.0 2.4 2 0 0 2 2 2 2 Putative sensor SARAF PF06682.12 KIK69469.1 - 0.11 12.1 1.3 11 5.6 0.0 2.2 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ADH_N PF08240.12 KIK69473.1 - 1e-30 105.8 5.2 1.7e-30 105.1 5.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK69473.1 - 4.2e-19 68.8 0.0 7.7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK69473.1 - 9.5e-07 28.3 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KIK69473.1 - 7.2e-06 27.1 0.0 1.1e-05 26.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK69473.1 - 0.0027 18.0 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KIK69473.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIK69473.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIK69473.1 - 0.03 14.4 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KIK69473.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_tranf_2_3 PF13641.6 KIK69474.1 - 3.7e-28 99.0 0.0 4.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK69474.1 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK69474.1 - 1.8e-06 27.6 0.0 1.4e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Serglycin PF04360.12 KIK69474.1 - 0.99 9.3 3.7 1.7 8.6 3.7 1.3 1 0 0 1 1 1 0 Serglycin SKN1 PF03935.15 KIK69476.1 - 5.4e-183 609.0 0.7 6.3e-183 608.8 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HSP70 PF00012.20 KIK69477.1 - 2.4e-161 537.9 1.0 2.4e-161 537.9 1.0 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIK69477.1 - 6.6e-12 44.9 0.4 1.8e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein TssO PF17561.2 KIK69477.1 - 0.17 12.0 1.5 7 6.8 0.5 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO F-box-like PF12937.7 KIK69478.1 - 9.5e-08 31.8 0.3 9.5e-08 31.8 0.3 2.6 2 0 0 2 2 2 1 F-box-like PRKG1_interact PF15898.5 KIK69478.1 - 0.0046 17.8 0.1 0.0094 16.8 0.1 1.4 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain F-box PF00646.33 KIK69478.1 - 0.023 14.5 0.8 0.18 11.7 0.0 3.1 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK69479.1 - 1.3e-08 34.6 0.3 3.9e-08 33.0 0.3 1.9 1 1 0 1 1 1 1 F-box-like PRKG1_interact PF15898.5 KIK69479.1 - 0.00064 20.6 0.1 0.00087 20.2 0.1 1.2 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain F-box PF00646.33 KIK69479.1 - 0.024 14.5 0.1 0.084 12.8 0.1 2.0 1 1 0 1 1 1 0 F-box domain GAS PF13851.6 KIK69479.1 - 0.059 12.7 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 KIK69480.1 - 3.9e-19 68.8 54.7 7.7e-16 58.0 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK69481.1 - 6.8e-21 74.6 55.8 8.2e-17 61.2 36.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK69482.1 - 3.1e-12 46.1 46.9 6.4e-12 45.1 20.5 2.5 2 1 0 3 3 3 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 KIK69483.1 - 7.2e-86 286.9 55.5 1.9e-49 167.9 23.3 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIK69483.1 - 9.8e-38 129.8 0.0 1.3e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIK69483.1 - 6.5e-35 118.9 15.7 8.9e-34 115.3 0.1 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK69483.1 - 5.2e-18 65.4 0.1 2.1e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 KIK69483.1 - 2e-08 34.1 0.9 3.5e-07 30.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KIK69483.1 - 2.6e-08 33.4 50.0 0.001 18.3 20.4 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KIK69483.1 - 2.8e-07 31.1 0.3 0.0032 17.9 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK69483.1 - 4.1e-06 26.8 0.0 0.28 10.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIK69483.1 - 2.9e-05 24.0 0.1 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KIK69483.1 - 4.3e-05 24.1 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIK69483.1 - 0.00024 21.3 0.2 0.4 10.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIK69483.1 - 0.00026 21.3 0.2 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK69483.1 - 0.00032 20.4 0.9 0.012 15.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK69483.1 - 0.00049 20.4 1.1 1.2 9.5 0.2 3.1 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 KIK69483.1 - 0.012 15.1 0.1 0.61 9.5 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIK69483.1 - 0.014 15.2 1.4 2.7 7.7 0.4 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK69483.1 - 0.017 15.1 1.1 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KIK69483.1 - 0.017 14.7 2.1 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KIK69483.1 - 0.036 14.0 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 KIK69483.1 - 0.053 14.0 1.5 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK69483.1 - 0.083 13.3 0.1 22 5.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK69483.1 - 0.094 12.4 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK69483.1 - 0.15 12.6 0.1 0.43 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KIK69483.1 - 0.16 11.7 0.1 20 4.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Glyco_hydro_76 PF03663.14 KIK69484.1 - 8.4e-41 140.7 10.6 1.1e-40 140.3 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KIK69484.1 - 0.00083 18.5 0.8 0.011 14.9 0.0 2.2 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 DnaJ-X PF14308.6 KIK69487.1 - 7.3e-51 172.6 0.1 7.3e-51 172.6 0.1 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIK69487.1 - 4e-26 90.9 0.6 9.5e-26 89.7 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_12 PF11331.8 KIK69487.1 - 0.11 12.3 0.4 0.21 11.4 0.4 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain Mu-like_Pro PF10123.9 KIK69487.1 - 1 8.8 7.1 7.2 6.1 4.6 2.4 1 1 1 2 2 2 0 Mu-like prophage I protein Sigma70_ner PF04546.13 KIK69487.1 - 2.5 8.0 10.8 0.48 10.3 2.0 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF3641 PF12345.8 KIK69488.1 - 0.03 14.3 0.4 0.069 13.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) p450 PF00067.22 KIK69489.1 - 2.1e-71 241.1 0.0 2.5e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Jacalin PF01419.17 KIK69491.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 1 0 1 1 1 0 Jacalin-like lectin domain DUF4232 PF14016.6 KIK69492.1 - 0.0082 16.3 0.1 0.0088 16.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) RICTOR_N PF14664.6 KIK69496.1 - 1.3e-121 406.1 0.7 6.7e-121 403.8 0.3 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KIK69496.1 - 1.5e-38 130.8 0.5 3.8e-36 123.0 0.0 3.9 3 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KIK69496.1 - 3.7e-35 120.6 0.2 6.7e-34 116.5 0.1 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KIK69496.1 - 8.8e-31 106.0 0.9 3.5e-27 94.4 0.0 4.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KIK69496.1 - 5.6e-06 26.4 2.8 1.4e-05 25.1 2.8 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 KIK69496.1 - 0.009 16.2 2.5 0.55 10.6 0.0 4.8 6 0 0 6 6 5 1 HEAT repeat HEAT_EZ PF13513.6 KIK69496.1 - 0.031 14.8 0.8 84 3.8 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 KIK69496.1 - 0.042 14.2 7.3 0.081 13.3 0.2 4.3 4 0 0 4 4 4 0 HEAT repeats Arc_PepC PF06819.11 KIK69496.1 - 0.055 13.6 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Protoglobin PF11563.8 KIK69496.1 - 0.11 12.4 0.1 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 Protoglobin MyTH4 PF00784.17 KIK69496.1 - 0.13 12.8 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 MyTH4 domain DUF1768 PF08719.11 KIK69497.1 - 5.4e-42 143.8 0.0 6.4e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) STE3 PF02076.15 KIK69499.1 - 3.4e-115 384.2 22.7 4.1e-115 384.0 22.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor Aldo_ket_red PF00248.21 KIK69500.1 - 2.6e-06 26.9 0.0 0.00012 21.4 0.0 2.3 1 1 1 2 2 2 2 Aldo/keto reductase family Motile_Sperm PF00635.26 KIK69502.1 - 4.3e-26 90.9 0.6 9.2e-26 89.8 0.2 1.7 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KIK69502.1 - 5.6e-05 23.3 0.1 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ABC_membrane PF00664.23 KIK69504.1 - 4.1e-100 334.9 26.9 1.4e-52 179.0 15.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK69504.1 - 1.6e-70 235.9 0.4 3.5e-34 118.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KIK69504.1 - 1.4e-14 54.1 4.5 3.7e-06 26.5 0.7 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIK69504.1 - 1.6e-08 33.8 0.3 0.0027 16.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KIK69504.1 - 2.3e-07 31.2 1.3 0.0085 16.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KIK69504.1 - 5.1e-07 29.2 0.0 0.019 14.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 KIK69504.1 - 6.1e-07 29.1 0.2 0.028 14.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK69504.1 - 1.4e-06 28.3 0.0 0.0034 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK69504.1 - 1.5e-06 28.2 0.0 0.049 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KIK69504.1 - 1.8e-06 28.5 3.9 0.0027 18.1 0.1 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KIK69504.1 - 4.8e-06 26.6 0.2 0.18 11.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KIK69504.1 - 0.00025 20.3 0.0 0.088 12.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 KIK69504.1 - 0.00032 21.2 0.0 0.51 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIK69504.1 - 0.00061 19.4 1.2 1.5 8.3 0.2 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KIK69504.1 - 0.00078 19.2 2.1 1.9 8.2 0.2 3.6 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KIK69504.1 - 0.0025 18.0 3.7 3.3 8.0 0.4 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KIK69504.1 - 0.0029 17.2 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KIK69504.1 - 0.0038 16.4 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.18 KIK69504.1 - 0.0047 16.7 0.0 0.6 9.8 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KIK69504.1 - 0.0062 16.5 0.1 3.3 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KIK69504.1 - 0.0095 15.8 0.1 3.9 7.3 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KIK69504.1 - 0.011 15.9 0.1 6.2 6.9 0.0 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KIK69504.1 - 0.012 16.0 4.2 1.5 9.2 0.4 4.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2628 PF10947.8 KIK69504.1 - 0.012 15.9 0.1 0.072 13.4 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) AAA_33 PF13671.6 KIK69504.1 - 0.017 15.3 0.0 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK69504.1 - 0.018 15.6 0.0 9.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK69504.1 - 0.019 14.1 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK69504.1 - 0.022 15.1 0.0 2.9 8.3 0.0 3.2 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 KIK69504.1 - 0.029 14.1 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIK69504.1 - 0.035 14.2 0.6 14 5.7 0.1 3.8 5 0 0 5 5 4 0 Helicase HerA, central domain Rad17 PF03215.15 KIK69504.1 - 0.039 13.9 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 KIK69504.1 - 0.24 11.8 2.4 24 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain Pkinase PF00069.25 KIK69505.1 - 1.5e-70 237.6 0.0 1.9e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69505.1 - 3.5e-31 108.4 0.0 4.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIK69505.1 - 3.6e-09 37.2 6.4 4.1e-09 37.0 4.2 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIK69505.1 - 4.4e-07 29.2 0.2 6.8e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK69505.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK69505.1 - 0.011 15.3 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK69505.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK69505.1 - 0.034 14.0 0.2 0.094 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK69505.1 - 0.16 11.5 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MutS_III PF05192.18 KIK69506.1 - 1.1e-30 107.4 0.1 2.5e-30 106.2 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 KIK69506.1 - 3.2e-30 105.6 0.0 2.3e-28 99.5 0.0 2.4 1 1 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 KIK69506.1 - 0.022 15.1 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV HMGL-like PF00682.19 KIK69507.1 - 1.8e-42 145.7 0.0 7.7e-42 143.7 0.0 1.8 1 1 0 1 1 1 1 HMGL-like Band_7 PF01145.25 KIK69508.1 - 2.6e-21 76.4 0.3 3.6e-21 76.0 0.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.14 KIK69509.1 - 1.4e-34 117.7 10.9 2.4e-19 68.9 2.3 2.9 2 0 0 2 2 2 2 PQ loop repeat Sdh_cyt PF01127.22 KIK69509.1 - 0.065 13.3 3.2 0.084 12.9 0.2 2.4 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit F-box-like PF12937.7 KIK69510.1 - 1.8e-10 40.5 1.0 6.5e-10 38.8 0.1 2.5 2 0 0 2 2 2 1 F-box-like CENP-C_C PF11699.8 KIK69511.1 - 2e-24 85.6 0.1 4.2e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIK69511.1 - 3.7e-05 23.4 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KIK69511.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Cupin tRNA_Me_trans PF03054.16 KIK69512.1 - 6.8e-121 403.4 0.0 7.8e-121 403.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KIK69512.1 - 5.2e-06 25.8 0.0 0.0011 18.2 0.0 2.5 2 1 0 2 2 2 2 NAD synthase ATP_bind_3 PF01171.20 KIK69512.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 KIK69512.1 - 0.044 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KIK69512.1 - 0.18 11.3 0.0 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC EMP24_GP25L PF01105.24 KIK69516.1 - 0.29 11.0 1.7 0.46 10.4 1.7 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.16 KIK69516.1 - 0.37 9.6 1.5 0.44 9.4 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KIK69516.1 - 0.98 9.6 4.7 3.2 8.0 3.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KIK69516.1 - 1.7 9.0 11.9 12 6.3 10.8 2.1 1 1 1 2 2 2 0 Fez1 DivIVA PF05103.13 KIK69516.1 - 6.1 6.9 10.4 3.4 7.8 7.0 2.1 2 0 0 2 2 2 0 DivIVA protein Myb_DNA-binding PF00249.31 KIK69517.1 - 0.0086 16.2 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Arm-DNA-bind_4 PF14657.6 KIK69517.1 - 0.064 13.0 0.6 0.17 11.7 0.6 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain zf-TRAF PF02176.18 KIK69518.1 - 5.8e-07 30.1 35.0 0.0011 19.6 7.1 4.9 1 1 4 5 5 5 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KIK69518.1 - 2.8e-06 27.1 10.9 2.8e-06 27.1 10.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ACC PF17848.1 KIK69518.1 - 1.9e-05 24.6 9.6 3.4e-05 23.8 1.6 3.7 3 0 0 3 3 3 1 Acetyl-coA carboxylase zinc finger domain zf-RING_UBOX PF13445.6 KIK69518.1 - 0.00015 21.7 12.3 0.00086 19.3 12.3 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 KIK69518.1 - 0.00016 21.4 5.8 0.00016 21.4 5.8 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-TRAF_2 PF15965.5 KIK69518.1 - 0.00017 22.0 28.8 0.00028 21.3 1.6 3.7 1 1 2 3 3 3 1 TRAF-like zinc-finger zf-RING_2 PF13639.6 KIK69518.1 - 0.00029 21.1 11.7 0.00029 21.1 11.7 3.6 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK69518.1 - 0.00068 19.5 11.8 0.00068 19.5 11.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK69518.1 - 0.0051 16.7 10.2 0.0051 16.7 10.2 3.3 2 1 1 3 3 1 1 zinc-RING finger domain Sina PF03145.16 KIK69518.1 - 0.0053 16.7 23.1 0.025 14.5 3.5 3.0 1 1 2 3 3 3 2 Seven in absentia protein family Cnn_1N PF07989.11 KIK69518.1 - 0.1 12.8 0.4 8.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf_UBZ PF18439.1 KIK69518.1 - 0.32 10.6 6.3 1.1 8.9 1.0 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HA2 PF04408.23 KIK69520.1 - 5.8e-28 97.3 0.0 5.8e-28 97.3 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK69520.1 - 3.4e-17 62.6 0.0 1.1e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK69520.1 - 1.3e-10 41.6 1.7 7.5e-10 39.1 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK69520.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK69520.1 - 2e-06 28.1 0.0 8.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIK69520.1 - 0.0029 17.9 0.1 0.014 15.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK69520.1 - 0.005 16.6 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KIK69520.1 - 0.036 14.6 0.0 0.036 14.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KIK69520.1 - 0.92 9.5 0.0 0.92 9.5 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit SEN1_N PF12726.7 KIK69521.1 - 3.5e-136 455.4 1.5 5.6e-136 454.7 1.5 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KIK69521.1 - 1.3e-68 231.6 5.7 1.3e-68 231.6 5.7 2.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KIK69521.1 - 1.2e-58 198.0 0.1 2.9e-58 196.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK69521.1 - 1.3e-10 41.4 0.1 9.2e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK69521.1 - 5.5e-10 39.7 0.0 1.9e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK69521.1 - 2.9e-09 37.0 0.6 0.0019 18.0 0.1 3.6 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KIK69521.1 - 0.00015 21.7 0.4 0.04 13.8 0.1 2.5 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 KIK69521.1 - 0.00025 21.1 0.0 0.00079 19.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK69521.1 - 0.0058 16.9 0.4 0.15 12.3 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA PF00004.29 KIK69521.1 - 0.0091 16.4 0.1 0.042 14.3 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK69521.1 - 0.015 15.8 0.2 0.015 15.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK69521.1 - 0.04 13.0 0.0 0.098 11.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KIK69521.1 - 0.053 13.9 0.7 0.21 11.9 0.3 2.4 2 1 0 2 2 2 0 AAA ATPase domain UvrD_C_2 PF13538.6 KIK69521.1 - 0.081 12.8 0.0 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF16 PF01519.16 KIK69521.1 - 0.29 11.7 1.5 1.1 9.8 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function DUF16 UvrD-helicase PF00580.21 KIK69521.1 - 1.1 8.7 10.1 0.035 13.6 2.2 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3232 PF11554.8 KIK69521.1 - 2.1 8.7 4.5 5.5 7.4 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) Translin PF01997.16 KIK69522.1 - 8.8e-47 159.7 0.1 1e-46 159.5 0.1 1.0 1 0 0 1 1 1 1 Translin family DUF1325 PF07039.11 KIK69523.1 - 1.7e-35 122.0 0.0 2.3e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KIK69523.1 - 0.0003 20.6 0.3 0.00064 19.5 0.1 1.7 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KIK69523.1 - 0.056 13.5 0.0 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KIK69523.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DNA_pol_B PF00136.21 KIK69524.1 - 1.1e-116 390.3 0.1 1.5e-116 389.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KIK69524.1 - 4.2e-51 173.3 8.3 7.8e-51 172.4 8.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KIK69524.1 - 5e-25 88.4 0.0 1.7e-24 86.6 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KIK69524.1 - 4.1e-21 74.8 8.2 1.6e-20 72.9 8.2 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KIK69524.1 - 0.081 11.8 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral UvrA_DNA-bind PF17755.1 KIK69524.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.9 1 0 0 1 1 1 0 UvrA DNA-binding domain Ogr_Delta PF04606.12 KIK69524.1 - 0.2 11.7 0.6 0.54 10.3 0.6 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 KIK69524.1 - 0.24 11.5 5.3 0.63 10.2 5.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF1932 PF09130.11 KIK69525.1 - 8.7e-14 51.2 0.0 2.2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KIK69525.1 - 8.9e-10 38.9 0.0 1.7e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK69525.1 - 4.4e-06 27.2 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KIK69525.1 - 3.3e-05 23.5 0.0 7.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KIK69525.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIK69525.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KIK69525.1 - 0.06 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L6 PF00347.23 KIK69526.1 - 6.9e-24 84.3 0.0 1.4e-11 44.9 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 ATP-synt_C PF00137.21 KIK69527.1 - 5.2e-32 110.0 33.2 3.1e-19 69.1 12.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_J PF04911.12 KIK69527.1 - 4.6 6.9 4.8 13 5.4 0.2 2.5 2 0 0 2 2 2 0 ATP synthase j chain zf-CCHC_3 PF13917.6 KIK69528.1 - 3.8e-20 71.6 1.6 5.8e-20 71.0 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle Inhibitor_I66 PF16850.5 KIK69528.1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I66 CBFD_NFYB_HMF PF00808.23 KIK69529.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Diphtheria_C PF02763.14 KIK69529.1 - 0.054 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Histone PF00125.24 KIK69529.1 - 0.062 13.7 2.2 0.78 10.1 0.0 2.7 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SAGA-Tad1 PF12767.7 KIK69529.1 - 0.069 12.9 1.6 7.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SOG2 PF10428.9 KIK69529.1 - 7.5 5.6 22.8 4.6 6.3 15.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein DIOX_N PF14226.6 KIK69530.1 - 8.6e-27 94.2 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK69530.1 - 1.3e-16 60.9 0.0 3e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KIK69533.1 - 1.1e-44 152.8 41.9 3.5e-40 138.0 41.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KIK69533.1 - 5.8e-06 24.9 17.8 9.3e-05 20.9 0.2 3.9 3 2 2 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KIK69533.1 - 0.00024 19.6 9.5 0.0049 15.3 9.5 3.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YfhO PF09586.10 KIK69533.1 - 0.038 12.2 0.2 0.062 11.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3043 PF11241.8 KIK69533.1 - 1.5 8.9 2.7 0.76 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF2207 PF09972.9 KIK69533.1 - 8.6 5.0 7.7 0.69 8.6 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) tRNA_bind PF01588.20 KIK69534.1 - 1.4e-28 98.8 0.0 2.6e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KIK69534.1 - 0.0072 16.5 0.1 0.0072 16.5 0.1 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK69534.1 - 0.0092 16.2 0.0 0.0092 16.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.12 KIK69534.1 - 0.061 13.6 1.6 0.078 13.3 1.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PIF1 PF05970.14 KIK69534.1 - 0.24 10.5 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase HSP20 PF00011.21 KIK69535.1 - 2.3e-12 47.0 0.2 5.3e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK69535.1 - 9.3e-06 25.1 0.0 2.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA OTT_1508_deam PF14441.6 KIK69535.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase MFS_1 PF07690.16 KIK69536.1 - 1.5e-37 129.4 29.4 1.5e-37 129.4 29.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK69536.1 - 1.2e-08 34.3 6.8 1.2e-08 34.3 6.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 KIK69536.1 - 0.0022 16.3 2.1 0.081 11.1 0.3 2.3 2 0 0 2 2 2 2 BT1 family TRI12 PF06609.13 KIK69536.1 - 0.0031 16.0 2.0 0.0045 15.5 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 KIK69536.1 - 0.43 10.2 3.3 1.3 8.6 3.3 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF5090 PF17009.5 KIK69536.1 - 2.6 7.9 4.9 6.9 6.6 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) CVNH PF08881.10 KIK69540.1 - 3.6e-18 66.1 0.0 9.8e-07 29.4 0.0 3.3 2 1 1 3 3 3 3 CVNH domain LeuA_dimer PF08502.10 KIK69540.1 - 0.0039 17.1 0.5 0.0077 16.1 0.5 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain E3_UbLigase_EDD PF11547.8 KIK69540.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD CVNH PF08881.10 KIK69541.1 - 3.4e-19 69.4 0.1 1.2e-10 41.9 0.0 3.5 2 1 1 3 3 3 3 CVNH domain HNOB PF07700.15 KIK69541.1 - 0.015 15.2 0.2 0.027 14.5 0.2 1.4 1 0 0 1 1 1 0 Haem-NO-binding DUF2373 PF10180.9 KIK69541.1 - 0.026 14.4 0.2 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) CVNH PF08881.10 KIK69542.1 - 5e-19 68.9 0.0 1.1e-10 42.1 0.0 3.4 2 1 1 3 3 3 3 CVNH domain DUF2373 PF10180.9 KIK69542.1 - 0.023 14.6 0.1 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) ABC_tran PF00005.27 KIK69543.1 - 2.7e-41 141.3 0.1 2.3e-24 86.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK69543.1 - 1.3e-14 54.6 19.3 3.3e-08 33.5 4.5 3.0 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK69543.1 - 2e-10 40.5 2.6 0.14 11.6 0.1 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK69543.1 - 1.9e-07 30.7 0.2 0.015 15.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KIK69543.1 - 2.3e-07 30.6 2.3 0.015 14.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 KIK69543.1 - 2.5e-06 27.1 0.1 0.0043 16.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KIK69543.1 - 2.4e-05 24.4 0.2 0.13 12.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KIK69543.1 - 6.8e-05 23.1 2.0 0.042 13.9 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 KIK69543.1 - 7.7e-05 23.1 2.4 0.27 11.6 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain T2SSE PF00437.20 KIK69543.1 - 9.8e-05 21.5 3.9 0.11 11.5 0.1 3.2 2 1 1 3 3 3 2 Type II/IV secretion system protein AAA_23 PF13476.6 KIK69543.1 - 0.00013 22.6 0.2 0.057 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIK69543.1 - 0.00055 19.8 9.8 0.34 10.7 0.9 4.0 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIK69543.1 - 0.00087 19.2 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KIK69543.1 - 0.0011 19.1 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK69543.1 - 0.0013 19.0 0.2 2.8 8.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KIK69543.1 - 0.0038 17.3 0.5 0.56 10.3 0.1 2.4 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.17 KIK69543.1 - 0.0063 16.3 0.2 1.5 8.5 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 KIK69543.1 - 0.0087 15.6 0.2 3.6 7.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 KIK69543.1 - 0.02 13.7 0.1 0.92 8.2 0.0 2.6 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_18 PF13238.6 KIK69543.1 - 0.029 14.9 0.0 4.8 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK69543.1 - 0.031 14.2 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KIK69543.1 - 0.039 13.2 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 KIK69543.1 - 0.05 12.7 0.1 0.67 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KIK69543.1 - 0.08 12.7 0.1 6.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 KIK69543.1 - 0.087 11.7 0.3 6.9 5.5 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 KIK69543.1 - 0.1 12.6 0.0 7.2 6.6 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KIK69543.1 - 0.11 12.3 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIK69543.1 - 0.15 11.8 0.1 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 KIK69543.1 - 0.33 10.4 1.2 5.3 6.4 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.9 KIK69543.1 - 3.9 6.2 5.3 1 8.1 0.3 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Hist_deacetyl PF00850.19 KIK69544.1 - 9.9e-49 166.5 0.0 1.4e-48 166.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Abhydrolase_3 PF07859.13 KIK69545.1 - 5.8e-18 65.5 0.0 1.1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK69545.1 - 1.1e-16 60.7 0.0 1.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase CRAL_TRIO PF00650.20 KIK69547.1 - 1.3e-23 83.4 0.0 1.9e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK69547.1 - 9e-05 22.6 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DNA_pol_E_B PF04042.16 KIK69549.1 - 2.1e-32 112.2 0.2 3.1e-32 111.7 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KIK69549.1 - 1.2e-21 77.9 0.1 2.7e-10 40.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal Ndc1_Nup PF09531.10 KIK69550.1 - 1.1e-88 298.6 0.6 1.2e-88 298.3 0.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup CS PF04969.16 KIK69551.1 - 3.4e-10 40.8 0.0 1.7e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 CS domain MT PF12777.7 KIK69552.1 - 0.001 18.2 1.9 0.0014 17.7 1.9 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor V_ATPase_I PF01496.19 KIK69552.1 - 4.5 5.1 6.1 5.8 4.7 6.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PP2C PF00481.21 KIK69554.1 - 2.9e-79 266.4 0.0 4.2e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK69554.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C zf-HIT PF04438.16 KIK69555.1 - 9.1 6.3 10.2 3.4 7.6 7.3 1.8 2 0 0 2 2 2 0 HIT zinc finger BUD22 PF09073.10 KIK69556.1 - 6.2e-76 256.5 28.0 7.1e-76 256.3 28.0 1.0 1 0 0 1 1 1 1 BUD22 TFCD_C PF12612.8 KIK69557.1 - 7.1e-44 149.9 0.1 1.5e-42 145.6 0.0 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KIK69557.1 - 2.2e-07 30.5 4.0 0.039 14.2 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KIK69557.1 - 0.0001 22.4 0.2 0.022 14.8 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK69557.1 - 0.0003 21.1 3.3 0.2 12.1 0.1 5.0 4 1 0 5 5 5 1 HEAT repeats RTP1_C1 PF10363.9 KIK69557.1 - 0.018 15.2 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KIK69557.1 - 0.026 13.1 0.6 1.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Adaptin N terminal region HEAT_PBS PF03130.16 KIK69557.1 - 0.082 13.6 1.8 2e+02 3.1 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KIK69557.1 - 3.4 8.3 8.1 8.8 7.0 0.0 5.1 7 0 0 7 7 7 0 HEAT-like repeat ATP-synt_ab PF00006.25 KIK69558.1 - 1.5e-67 227.4 0.0 2e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIK69558.1 - 1.5e-12 47.9 0.5 2.6e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tcp11 PF05794.13 KIK69559.1 - 1.7e-85 287.8 0.0 2.3e-85 287.3 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 DLH PF01738.18 KIK69560.1 - 9.2e-19 67.8 0.0 2.3e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK69560.1 - 0.00065 19.4 0.1 0.0072 16.0 0.0 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69560.1 - 0.013 16.1 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KIK69561.1 - 4.1e-19 69.0 0.0 1.4e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK69561.1 - 0.016 14.8 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69561.1 - 0.021 15.5 0.0 0.025 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 KIK69561.1 - 0.035 13.2 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Amidohydro_1 PF01979.20 KIK69562.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family RGS PF00615.19 KIK69563.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain Acetyltransf_3 PF13302.7 KIK69564.1 - 3.8e-23 82.7 0.1 5e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK69564.1 - 3.7e-15 56.2 0.1 5.1e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIK69564.1 - 5.3e-12 46.1 0.1 6.3e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK69564.1 - 5.4e-07 30.0 0.1 8.2e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK69564.1 - 1.3e-06 28.2 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK69564.1 - 1.7e-06 28.0 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK69564.1 - 0.00029 20.8 0.1 0.00055 19.8 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Cytomega_UL84 PF06284.11 KIK69564.1 - 0.095 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Acetyltransf_3 PF13302.7 KIK69565.1 - 1e-24 87.7 0.1 1.5e-24 87.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK69565.1 - 1.2e-11 44.8 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIK69565.1 - 6.8e-11 42.5 0.0 8.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK69565.1 - 6.7e-06 25.8 0.1 1.7e-05 24.5 0.1 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK69565.1 - 2.1e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK69565.1 - 4.1e-05 23.5 0.0 5.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK69565.1 - 0.00047 20.5 0.0 0.00066 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KIK69566.1 - 8e-29 100.7 32.6 2.8e-20 72.6 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK69566.1 - 1.2e-21 77.1 16.3 1.7e-21 76.6 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Myc_target_1 PF15179.6 KIK69566.1 - 0.033 14.1 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 Myc target protein 1 Acetyltransf_3 PF13302.7 KIK69567.1 - 3.1e-23 83.0 0.0 3.7e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK69567.1 - 1.5e-14 54.4 0.1 1.7e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK69567.1 - 2.2e-14 53.7 0.0 2.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK69567.1 - 8.4e-07 29.3 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK69567.1 - 3e-05 23.9 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIK69567.1 - 4.1e-05 23.3 0.0 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK69567.1 - 4.6e-05 23.4 0.0 5.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.7 KIK69568.1 - 2.5e-09 36.9 0.0 1.2e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK69568.1 - 0.068 13.1 0.6 7.4 6.6 0.1 2.9 2 0 0 2 2 2 0 F-box domain NMO PF03060.15 KIK69569.1 - 6.3e-56 190.1 1.7 4.2e-55 187.4 1.7 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK69569.1 - 1.1e-10 41.1 0.9 0.00016 20.8 0.6 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK69569.1 - 0.0006 18.9 1.3 0.00096 18.3 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 KIK69569.1 - 0.0028 17.0 0.1 0.0062 15.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase NanE PF04131.14 KIK69569.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 KIK69569.1 - 0.087 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glyco_transf_28 PF03033.20 KIK69570.1 - 3.2e-27 95.3 0.0 6.2e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIK69570.1 - 4.2e-08 32.4 0.0 1.3e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.20 KIK69570.1 - 5.8e-06 26.2 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 GRAM domain CVNH PF08881.10 KIK69571.1 - 1.1e-19 71.0 0.1 4.1e-14 53.1 0.0 2.1 1 1 1 2 2 2 2 CVNH domain ParcG PF10274.9 KIK69572.1 - 0.005 17.0 0.4 0.041 14.0 0.2 1.9 1 1 1 2 2 2 1 Parkin co-regulated protein DUF2294 PF10057.9 KIK69572.1 - 0.015 15.4 2.3 1.6 8.9 0.4 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF826 PF05696.11 KIK69572.1 - 0.055 13.6 1.1 0.16 12.1 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF826) DUF2373 PF10180.9 KIK69572.1 - 0.11 12.3 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Gpi1 PF05024.15 KIK69572.1 - 0.2 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) DUF4549 PF15082.6 KIK69572.1 - 0.33 10.7 2.9 0.29 10.9 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) CVNH PF08881.10 KIK69573.1 - 1.1e-24 87.1 0.0 3.3e-09 37.3 0.0 3.6 2 1 1 3 3 3 3 CVNH domain CVNH PF08881.10 KIK69574.1 - 4.5e-19 69.0 0.1 3.6e-13 50.1 0.0 2.1 1 1 1 2 2 2 2 CVNH domain DAHP_synth_1 PF00793.20 KIK69575.1 - 5.4e-95 317.4 0.0 6.8e-95 317.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.15 KIK69576.1 - 7e-19 67.2 6.8 9.6e-19 66.8 6.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 KIK69576.1 - 0.011 16.0 0.1 2 8.7 0.0 2.1 1 1 1 2 2 2 0 Phasin protein DUF2156 PF09924.9 KIK69576.1 - 0.1 11.6 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) AhpC-TSA PF00578.21 KIK69577.1 - 2.4e-27 95.3 0.0 3e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK69577.1 - 2.4e-16 59.8 0.0 3.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin WD40 PF00400.32 KIK69578.1 - 1.3e-10 41.7 14.7 0.03 15.2 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.6 KIK69578.1 - 0.38 11.3 1.5 4.7 7.8 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain zf-CCHC PF00098.23 KIK69579.1 - 0.13 12.4 0.7 0.21 11.7 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Lactamase_B PF00753.27 KIK69581.1 - 2.7e-11 43.9 1.2 4.1e-11 43.2 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK69581.1 - 0.054 13.0 1.0 0.099 12.1 0.1 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK69582.1 - 4.4e-09 36.6 0.6 5.4e-09 36.3 0.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK69582.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_S19e PF01090.19 KIK69583.1 - 1.7e-57 193.0 0.1 1.9e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.7 KIK69584.1 - 2.3e-08 33.8 0.1 1.2e-07 31.5 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK69584.1 - 0.0019 18.0 0.2 0.023 14.6 0.0 3.0 3 0 0 3 3 3 1 F-box domain MnhB PF04039.13 KIK69585.1 - 0.41 10.9 5.0 0.45 10.8 0.9 2.6 1 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Glyco_hydro_11 PF00457.17 KIK69587.1 - 1.5e-74 249.5 21.7 1.5e-74 249.5 21.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KIK69587.1 - 5.3e-13 48.7 12.3 5.3e-13 48.7 12.3 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Pkinase PF00069.25 KIK69588.1 - 4.9e-53 180.2 0.0 6e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69588.1 - 2.6e-27 95.8 0.0 3.4e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK69588.1 - 0.00013 21.4 0.0 0.0031 16.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KIK69588.1 - 0.0051 16.4 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK69588.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK69588.1 - 0.0086 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KIK69588.1 - 0.058 13.0 0.2 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK69588.1 - 0.067 13.1 0.0 0.48 10.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF5405 PF17399.2 KIK69588.1 - 0.095 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) Type2_restr_D3 PF16902.5 KIK69589.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain CVNH PF08881.10 KIK69590.1 - 4.3e-09 37.0 0.2 4.9e-09 36.8 0.2 1.1 1 0 0 1 1 1 1 CVNH domain EzrA PF06160.12 KIK69591.1 - 0.0011 17.2 10.5 0.0011 17.2 10.5 2.3 1 1 0 2 2 2 1 Septation ring formation regulator, EzrA NCKAP5 PF15246.6 KIK69591.1 - 0.0064 16.1 7.5 0.0064 16.1 7.5 2.6 3 0 0 3 3 3 1 Nck-associated protein 5, Peripheral clock protein Filament PF00038.21 KIK69591.1 - 0.016 14.8 25.7 0.033 13.8 4.8 3.0 1 1 1 2 2 2 0 Intermediate filament protein DUF713 PF05218.14 KIK69591.1 - 0.13 12.0 8.5 2.1 8.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF713) KxDL PF10241.9 KIK69591.1 - 0.16 12.3 9.8 0.091 13.0 1.3 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF724 PF05266.14 KIK69591.1 - 0.28 11.0 25.5 0.013 15.4 10.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 KIK69591.1 - 1.1 7.8 14.8 2.3 6.8 14.8 1.4 1 0 0 1 1 1 0 AAA domain GNVR PF13807.6 KIK69591.1 - 1.4 8.8 3.0 24 4.9 0.2 2.5 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase GAS PF13851.6 KIK69591.1 - 1.9 7.8 24.8 0.62 9.4 20.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KIK69591.1 - 2.2 8.3 4.0 3 7.9 0.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 KIK69591.1 - 2.3 6.5 32.0 0.048 12.0 25.1 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF745 PF05335.13 KIK69591.1 - 4.4 7.0 11.3 3 7.6 8.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) XhlA PF10779.9 KIK69591.1 - 5.5 7.3 13.5 3.6 7.9 5.8 3.0 2 0 0 2 2 2 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 KIK69591.1 - 5.8 7.0 38.3 0.19 11.8 21.4 3.1 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein EMP24_GP25L PF01105.24 KIK69591.1 - 6.5 6.7 7.2 0.61 10.0 1.5 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Trans_coact PF16805.5 KIK69592.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage late-transcription coactivator FA_desaturase PF00487.24 KIK69594.1 - 5.3e-20 72.3 23.8 1.4e-19 71.0 23.8 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIK69594.1 - 4.1e-05 23.8 0.0 9.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pkinase PF00069.25 KIK69595.1 - 1.2e-15 57.6 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69595.1 - 4e-07 29.6 0.0 1.4e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Ribosomal_S19e PF01090.19 KIK69595.1 - 0.0064 16.2 0.3 1.3 8.7 0.1 2.5 2 0 0 2 2 2 2 Ribosomal protein S19e Pkinase_fungal PF17667.1 KIK69595.1 - 0.016 14.0 1.6 0.017 13.9 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase TPP_enzyme_N PF02776.18 KIK69596.1 - 6.1e-30 104.1 0.1 1.2e-28 99.8 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK69596.1 - 4.4e-14 52.4 0.0 8.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIK69596.1 - 1.5e-13 50.8 0.0 3.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 KIK69596.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Chitin_synth_1 PF01644.17 KIK69596.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Chitin synthase Lactamase_B PF00753.27 KIK69598.1 - 2e-10 41.0 0.3 3.5e-10 40.2 0.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK69598.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain D123 PF07065.14 KIK69599.1 - 3.7e-97 325.2 0.4 4.5e-97 324.9 0.4 1.1 1 0 0 1 1 1 1 D123 Ribosomal_L34e PF01199.18 KIK69600.1 - 6.7e-43 144.9 2.6 9.3e-43 144.5 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KIK69600.1 - 0.12 12.3 2.6 2.3 8.2 0.4 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Cyclin_N PF00134.23 KIK69601.1 - 4.2e-11 42.7 0.0 6.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK69601.1 - 1.2e-06 29.0 1.9 2.2e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 Cyclin PBP_N PF17093.5 KIK69601.1 - 4 7.7 8.5 1.1 9.6 3.8 2.1 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus Rho_N PF07498.12 KIK69602.1 - 0.00057 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain HypA PF01155.19 KIK69602.1 - 0.006 16.6 0.2 2.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ish1 PF10281.9 KIK69602.1 - 0.012 15.9 0.6 0.028 14.7 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KIK69602.1 - 0.036 13.8 0.1 0.077 12.8 0.1 1.6 1 0 0 1 1 1 0 SAP domain zf_C2H2_13 PF18508.1 KIK69602.1 - 0.063 12.9 0.1 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Zinc finger domain ADD_ATRX PF17981.1 KIK69602.1 - 0.07 13.0 0.4 7.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Cysteine Rich ADD domain DUF678 PF05077.12 KIK69602.1 - 0.071 13.2 0.2 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF678) BIR PF00653.21 KIK69602.1 - 0.27 11.9 1.9 8 7.2 0.5 2.5 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain F-actin_cap_A PF01267.17 KIK69604.1 - 2.5e-99 332.0 0.0 2.8e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit FAD_binding_3 PF01494.19 KIK69605.1 - 4.9e-25 88.5 0.0 7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK69605.1 - 1.7e-08 34.5 0.6 2.1e-07 31.0 1.1 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK69605.1 - 2.9e-08 33.4 0.2 0.00013 21.4 0.2 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIK69605.1 - 1.5e-05 24.4 0.7 9.9e-05 21.7 0.3 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK69605.1 - 2e-05 23.6 0.1 0.0014 17.6 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KIK69605.1 - 5.7e-05 22.4 2.2 0.00011 21.4 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK69605.1 - 0.0002 21.0 0.6 0.0002 21.0 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK69605.1 - 0.00031 19.9 0.6 0.19 10.7 0.7 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KIK69605.1 - 0.00035 19.4 0.0 0.00064 18.5 0.0 1.4 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIK69605.1 - 0.00066 20.2 0.3 0.005 17.4 0.0 2.6 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK69605.1 - 0.00069 18.9 0.3 0.0014 18.0 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIK69605.1 - 0.023 14.0 0.1 0.05 12.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIK69605.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase ApbA PF02558.16 KIK69605.1 - 0.059 13.0 1.1 0.11 12.1 0.6 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KIK69605.1 - 0.072 12.4 0.4 0.16 11.2 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KIK69605.1 - 0.51 9.4 3.7 0.15 11.1 0.8 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK69605.1 - 0.59 9.4 8.7 0.039 13.3 3.7 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pet127 PF08634.10 KIK69607.1 - 2.3e-105 351.9 0.0 3.3e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 AOX PF01786.17 KIK69608.1 - 1.1e-95 319.2 0.2 1.4e-95 318.9 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase PH_4 PF15404.6 KIK69609.1 - 5.2e-21 75.3 0.0 1.8e-19 70.2 0.0 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain Ribosom_S12_S23 PF00164.25 KIK69610.1 - 4.4e-35 119.7 0.7 5.4e-35 119.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Arf PF00025.21 KIK69611.1 - 2.1e-41 141.2 0.0 2.4e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KIK69611.1 - 2.8e-19 69.3 0.0 3.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK69611.1 - 3.5e-16 59.5 0.0 4.9e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK69611.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK69611.1 - 2.9e-07 30.6 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK69611.1 - 3.9e-07 29.7 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KIK69611.1 - 1e-05 24.9 1.3 9.3e-05 21.7 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 KIK69611.1 - 0.00082 19.0 0.0 0.0054 16.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF751 PF05421.11 KIK69611.1 - 0.037 14.8 0.6 0.07 13.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF751) DUF2205 PF10224.9 KIK69612.1 - 5.8e-10 39.0 1.1 6.8e-10 38.8 1.1 1.1 1 0 0 1 1 1 1 Short coiled-coil protein DivIC PF04977.15 KIK69612.1 - 0.028 14.2 0.9 0.038 13.8 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KIK69612.1 - 0.029 15.0 1.3 0.033 14.8 1.3 1.1 1 0 0 1 1 1 0 Initiation control protein YabA WASH_WAHD PF11945.8 KIK69612.1 - 0.041 13.4 0.1 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 WAHD domain of WASH complex Herpes_IE2_3 PF03361.14 KIK69612.1 - 0.062 13.2 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 TolA_bind_tri PF16331.5 KIK69612.1 - 0.072 13.2 0.7 0.099 12.7 0.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4094 PF13334.6 KIK69612.1 - 0.095 13.1 0.2 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) RPN13_C PF16550.5 KIK69613.1 - 8.8e-29 99.9 0.0 1.5e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KIK69613.1 - 1.7e-27 95.8 0.0 2.5e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF1631 PF07793.11 KIK69613.1 - 0.033 12.6 0.4 0.039 12.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RdRP PF05183.12 KIK69614.1 - 3.6e-160 534.4 0.0 4.6e-160 534.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase zf-Nse PF11789.8 KIK69615.1 - 1.9e-16 59.6 0.0 3.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIK69615.1 - 1.2e-05 25.3 0.1 2.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK69615.1 - 0.0032 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KIK69615.1 - 0.013 14.8 0.0 0.013 14.8 0.0 3.0 2 1 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 KIK69615.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIK69615.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KIK69615.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK69615.1 - 0.13 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KIK69615.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3246 PF11596.8 KIK69615.1 - 2.3 7.6 8.5 6.6 6.1 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SET PF00856.28 KIK69616.1 - 1.1e-11 45.5 0.2 2.7e-10 40.9 0.2 2.3 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 KIK69616.1 - 3.7e-06 26.7 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK69616.1 - 0.0051 16.6 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Glycos_transf_4 PF00953.21 KIK69617.1 - 7.5e-31 107.3 7.8 7.5e-31 107.3 7.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 ICL PF00463.21 KIK69618.1 - 1.9e-257 854.9 0.1 2.2e-257 854.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIK69618.1 - 1.4e-08 34.5 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 KIK69618.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Amino_oxidase PF01593.24 KIK69619.1 - 8.5e-21 74.8 0.0 3.8e-18 66.0 0.0 3.1 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK69619.1 - 2.3e-14 53.3 0.0 9.7e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK69619.1 - 1.8e-06 27.8 0.0 0.00065 19.4 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK69619.1 - 3.4e-05 23.9 0.0 0.5 10.3 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIK69619.1 - 0.027 13.7 0.0 0.47 9.6 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SWIRM PF04433.17 KIK69620.1 - 9.2e-32 109.2 0.1 1.5e-30 105.4 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KIK69620.1 - 3.4e-20 71.8 7.7 3.4e-20 71.8 7.7 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KIK69620.1 - 1.2e-11 44.6 0.0 3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK69620.1 - 5.5e-09 36.2 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIK69620.1 - 1.5e-07 31.1 2.7 2.6e-07 30.3 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Chordopox_RPO7 PF05864.12 KIK69620.1 - 0.1 12.9 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ADH_zinc_N PF00107.26 KIK69621.1 - 5.5e-27 94.3 0.2 1.2e-26 93.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK69621.1 - 1.2e-26 92.7 1.3 2.1e-26 91.9 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK69621.1 - 2.8e-05 25.2 0.0 4.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3808 PF10300.9 KIK69622.1 - 4.6e-75 253.2 0.0 6.2e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Methyltransf_23 PF13489.6 KIK69623.1 - 9.6e-14 51.5 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK69623.1 - 3.4e-08 34.0 0.0 6.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK69623.1 - 3e-06 27.8 0.0 1.1e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK69623.1 - 1.6e-05 25.6 0.0 4.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69623.1 - 0.006 16.4 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 KIK69623.1 - 0.034 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 KIK69623.1 - 0.13 13.3 0.0 0.24 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HTH_Tnp_Tc5 PF03221.16 KIK69625.1 - 2e-11 43.8 0.2 7.1e-11 42.0 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KIK69625.1 - 9.9e-05 21.9 0.0 0.00045 19.8 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 KIK69625.1 - 0.0016 18.2 1.8 0.045 13.6 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 KIK69625.1 - 0.082 12.7 0.7 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 KIK69625.1 - 0.093 12.9 0.1 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KIK69625.1 - 0.11 12.9 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Transposase Malic_M PF03949.15 KIK69626.1 - 5.4e-94 314.3 0.0 6.8e-94 313.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIK69626.1 - 2.4e-64 216.5 0.0 4.9e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MRP-L20 PF12824.7 KIK69627.1 - 1.2e-21 77.6 5.8 4.7e-21 75.6 5.8 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 KIK69627.1 - 0.0059 17.2 0.3 0.0059 17.2 0.3 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Neugrin PF06413.11 KIK69627.1 - 0.061 13.3 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 Neugrin YdaS_antitoxin PF15943.5 KIK69627.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DLH PF01738.18 KIK69628.1 - 6.1e-19 68.4 0.0 1.2e-18 67.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK69628.1 - 0.016 14.8 0.0 0.053 13.2 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69628.1 - 0.025 15.2 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M22 PF00814.25 KIK69629.1 - 9.7e-64 215.7 0.2 1.2e-63 215.4 0.2 1.1 1 0 0 1 1 1 1 Glycoprotease family PLAC9 PF15205.6 KIK69630.1 - 0.036 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Placenta-specific protein 9 HAT_KAT11 PF08214.11 KIK69631.1 - 1.1e-43 149.8 0.0 1.7e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF2244 PF10003.9 KIK69632.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) T6SS_VasJ PF16989.5 KIK69632.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Cullin PF00888.22 KIK69633.1 - 4.1e-185 617.0 20.4 5.4e-185 616.6 20.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK69633.1 - 1e-24 86.3 2.4 1e-24 86.3 2.4 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4980 PF16352.5 KIK69633.1 - 0.016 15.2 0.0 0.053 13.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) MarR_2 PF12802.7 KIK69633.1 - 0.098 12.6 0.0 5.7 6.9 0.0 2.8 3 0 0 3 3 3 0 MarR family Rrf2 PF02082.20 KIK69633.1 - 0.13 12.6 0.4 0.68 10.3 0.4 2.3 2 0 0 2 2 2 0 Transcriptional regulator Ubie_methyltran PF01209.18 KIK69634.1 - 1.6e-78 263.2 0.0 2e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KIK69634.1 - 3.8e-14 53.2 0.0 2.2e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK69634.1 - 2.4e-11 44.1 0.1 1.1e-10 42.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69634.1 - 1.2e-10 41.4 0.0 2.5e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK69634.1 - 2.6e-08 34.5 0.0 4.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK69634.1 - 3.1e-08 33.6 0.0 4.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIK69634.1 - 0.071 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fcf2 PF08698.11 KIK69635.1 - 6e-30 103.5 0.3 1.3e-29 102.4 0.0 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing SR-25 PF10500.9 KIK69635.1 - 0.025 14.2 10.1 0.066 12.8 7.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ABC_membrane PF00664.23 KIK69636.1 - 4.7e-33 115.0 13.8 8.3e-21 74.8 9.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK69636.1 - 4.9e-24 85.4 1.5 1e-23 84.4 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Sas10 PF09368.10 KIK69636.1 - 8.8e-24 83.8 2.3 8.8e-24 83.8 2.3 3.2 3 0 0 3 3 2 1 Sas10 C-terminal domain DUF2462 PF09495.10 KIK69636.1 - 1e-18 67.8 16.4 1e-18 67.8 16.4 3.8 3 1 0 3 3 2 1 Protein of unknown function (DUF2462) Sas10_Utp3 PF04000.15 KIK69636.1 - 2.2e-06 28.2 0.4 1e-05 26.0 0.4 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SMC_N PF02463.19 KIK69636.1 - 0.00039 19.9 1.1 0.094 12.1 1.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK69636.1 - 0.0014 19.1 0.2 0.0061 17.0 0.2 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIK69636.1 - 0.04 13.7 4.8 3.7 7.3 0.1 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIK69636.1 - 0.04 14.0 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KIK69636.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KIK69636.1 - 0.6 10.4 2.9 9.2 6.5 0.3 3.0 2 1 0 2 2 2 0 AAA domain NAD_binding_10 PF13460.6 KIK69637.1 - 2.6e-11 43.8 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK69637.1 - 3.7e-11 43.0 0.0 5.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KIK69637.1 - 1.6e-10 40.5 0.0 2.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK69637.1 - 4.3e-10 39.5 0.0 1e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK69637.1 - 2.6e-09 36.6 0.0 4.1e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIK69637.1 - 2.1e-07 30.4 0.2 0.002 17.4 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK69637.1 - 0.00021 20.8 0.0 0.00048 19.6 0.0 1.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK69637.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69637.1 - 0.0027 17.3 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TatD_DNase PF01026.21 KIK69637.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase KR PF08659.10 KIK69637.1 - 0.15 12.0 0.0 0.6 10.0 0.0 1.9 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KIK69637.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein HIM1 PF08732.10 KIK69637.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 HIM1 Tom22 PF04281.13 KIK69638.1 - 1.8e-36 124.9 0.4 2.4e-36 124.6 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Zn_clus PF00172.18 KIK69639.1 - 1.3e-07 31.6 10.3 2.2e-07 30.9 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK69639.1 - 1.3e-05 24.4 0.9 0.00039 19.5 0.9 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Usp PF00582.26 KIK69641.1 - 3.5e-20 72.9 0.1 3.5e-20 72.9 0.1 2.1 2 0 0 2 2 2 1 Universal stress protein family MFS_1 PF07690.16 KIK69642.1 - 1.3e-21 77.0 46.2 1.9e-20 73.1 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PITH PF06201.13 KIK69643.1 - 1.8e-38 132.2 0.0 2.3e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 PITH domain Peptidase_M3 PF01432.20 KIK69644.1 - 2.6e-133 445.6 0.0 3.5e-133 445.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KIK69644.1 - 0.042 13.5 0.6 0.069 12.8 0.6 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Pkinase PF00069.25 KIK69646.1 - 3.8e-38 131.4 0.0 5.3e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69646.1 - 4e-26 91.9 0.0 5.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB2 PF18409.1 KIK69646.1 - 2.1e-06 28.4 0.0 6.1e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 KIK69646.1 - 0.00036 20.7 0.0 0.00099 19.3 0.0 1.8 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Pkinase_fungal PF17667.1 KIK69646.1 - 0.081 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIK69646.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GyrB_insert PF18053.1 KIK69646.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain Exo_endo_phos PF03372.23 KIK69647.1 - 8e-05 22.3 0.5 0.00038 20.0 0.5 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CHASE3 PF05227.13 KIK69650.1 - 0.00081 19.3 0.8 0.0012 18.8 0.8 1.3 1 0 0 1 1 1 1 CHASE3 domain RP-C PF03428.13 KIK69650.1 - 0.0066 16.1 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain Phage_HK97_TLTM PF06120.11 KIK69650.1 - 0.009 15.2 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Tail length tape measure protein RRF PF01765.19 KIK69650.1 - 0.0098 15.9 0.6 0.016 15.1 0.6 1.3 1 0 0 1 1 1 1 Ribosome recycling factor BLOC1_2 PF10046.9 KIK69650.1 - 0.011 16.0 1.2 0.049 13.9 0.9 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 KIK69650.1 - 0.041 14.3 1.0 0.1 13.1 1.0 1.7 1 0 0 1 1 1 0 Cell division protein ZapB DUF1664 PF07889.12 KIK69650.1 - 0.047 13.7 0.8 0.52 10.4 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KIK69650.1 - 0.14 12.7 1.1 0.46 11.0 0.7 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein POP1 PF06978.11 KIK69651.1 - 4.3e-46 157.5 19.3 4.8e-26 92.0 3.1 2.8 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KIK69651.1 - 6.8e-32 109.7 0.4 1.8e-31 108.3 0.4 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 KIK69651.1 - 0.00018 21.0 0.0 0.44 9.9 0.0 3.8 4 0 0 4 4 4 2 Aminomethyltransferase folate-binding domain Nbl1_Borealin_N PF10444.9 KIK69652.1 - 6.6e-17 60.9 0.7 1.1e-16 60.2 0.7 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 KIK69652.1 - 0.00036 20.5 5.1 0.00086 19.3 1.2 2.9 2 1 1 3 3 3 1 Cell division cycle-associated protein 8 3Beta_HSD PF01073.19 KIK69653.1 - 6.7e-66 222.1 0.0 5.2e-61 206.1 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK69653.1 - 9.5e-35 120.2 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK69653.1 - 4.6e-19 69.0 0.1 4.6e-15 55.9 0.1 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK69653.1 - 2.2e-13 50.5 0.1 3.6e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK69653.1 - 7.6e-12 44.9 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIK69653.1 - 8.1e-11 41.6 0.0 3.8e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KIK69653.1 - 8.5e-07 28.4 0.3 6.9e-06 25.4 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIK69653.1 - 0.011 15.7 0.7 0.77 9.6 0.1 2.6 1 1 1 2 2 2 0 KR domain NmrA PF05368.13 KIK69653.1 - 0.019 14.5 0.4 0.14 11.7 0.4 2.0 1 1 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 KIK69653.1 - 0.12 12.6 0.1 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain PROCN PF08083.11 KIK69656.1 - 1e-231 768.8 11.2 1.6e-231 768.2 9.7 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KIK69656.1 - 5.6e-127 422.1 0.6 1.4e-126 420.8 0.5 1.7 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KIK69656.1 - 6.5e-88 292.7 5.8 1.2e-87 291.9 2.3 2.8 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KIK69656.1 - 6.3e-85 282.7 2.1 6.3e-85 282.7 2.1 2.4 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KIK69656.1 - 3.3e-73 244.1 0.1 6.6e-73 243.1 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KIK69656.1 - 2.7e-46 155.8 0.4 6.4e-46 154.6 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KIK69656.1 - 2.8e-41 140.3 0.0 6.1e-41 139.2 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KIK69656.1 - 0.0019 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1353 PF07087.11 KIK69656.1 - 0.15 11.7 0.1 0.53 10.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Bestrophin PF01062.21 KIK69657.1 - 6.8e-37 127.5 0.2 4.6e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2177 PF09945.9 KIK69657.1 - 0.036 14.2 0.4 0.079 13.1 0.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) putAbiC PF16872.5 KIK69657.1 - 0.2 12.4 0.0 0.36 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative phage abortive infection protein dUTPase PF00692.19 KIK69658.1 - 9.6e-42 141.7 0.0 1.2e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase PLDc PF00614.22 KIK69659.1 - 8e-13 48.0 0.4 3e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 KIK69659.1 - 9.3e-13 48.2 0.6 7e-11 42.1 0.2 2.9 3 0 0 3 3 3 1 PX domain PLDc_2 PF13091.6 KIK69659.1 - 1.5e-12 47.6 0.0 1.7e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PH PF00169.29 KIK69659.1 - 0.0017 18.8 0.6 0.13 12.7 0.1 2.6 2 0 0 2 2 2 1 PH domain FAD_binding_2 PF00890.24 KIK69660.1 - 3.8e-46 158.0 0.5 6.4e-39 134.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIK69660.1 - 8.5e-10 38.7 1.7 8.5e-10 38.7 1.7 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK69660.1 - 1e-08 35.0 0.5 4.8e-07 29.5 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK69660.1 - 1.1e-06 27.7 0.2 0.053 12.2 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 KIK69660.1 - 3.1e-06 26.6 0.2 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK69660.1 - 3.8e-06 26.2 0.2 0.00046 19.4 0.2 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK69660.1 - 0.0017 18.5 0.2 0.011 16.0 0.3 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KIK69660.1 - 0.012 15.0 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIK69660.1 - 0.15 11.3 0.0 4.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK69660.1 - 0.69 9.1 4.1 8.2 5.6 0.0 2.7 3 0 0 3 3 3 0 Thi4 family ThiF PF00899.21 KIK69661.1 - 2e-28 99.4 0.0 2.6e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Spidroin_MaSp PF11260.8 KIK69661.1 - 0.058 13.7 1.4 0.11 12.8 0.7 1.8 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Fungal_trans PF04082.18 KIK69662.1 - 4.6e-19 68.5 0.0 7.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK69662.1 - 1.2e-08 34.9 9.9 2.2e-08 34.1 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 KIK69663.1 - 7.9e-06 26.0 0.0 0.009 16.2 0.0 4.0 3 1 1 4 4 4 1 PPR repeat family PPR PF01535.20 KIK69663.1 - 0.002 18.3 0.1 1.1 9.6 0.0 4.9 6 0 0 6 6 6 1 PPR repeat TPR_16 PF13432.6 KIK69663.1 - 0.025 15.2 1.7 0.22 12.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 KIK69663.1 - 0.069 12.9 0.5 0.41 10.4 0.0 2.7 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.6 KIK69663.1 - 0.21 11.7 0.4 2.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 KIK69663.1 - 0.28 12.1 4.6 0.79 10.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat GRASP55_65 PF04495.14 KIK69664.1 - 1.7e-59 200.1 0.0 1.5e-43 148.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KIK69664.1 - 3.1e-05 23.7 0.0 0.0005 19.8 0.0 2.7 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KIK69664.1 - 3.6e-05 24.0 0.0 0.073 13.4 0.0 2.2 2 0 0 2 2 2 2 PDZ domain RRM_1 PF00076.22 KIK69665.1 - 1.4e-52 175.3 0.5 5.3e-19 67.8 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short_C2 PF13561.6 KIK69665.1 - 1.5e-38 132.7 0.1 2.7e-37 128.6 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK69665.1 - 3e-35 121.5 0.9 8e-35 120.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RRM_occluded PF16842.5 KIK69665.1 - 2.5e-11 43.3 0.0 0.0021 17.9 0.0 4.6 4 0 0 4 4 4 3 Occluded RNA-recognition motif KR PF08659.10 KIK69665.1 - 8.1e-07 29.1 0.1 2.4e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 KR domain Suf PF05843.14 KIK69665.1 - 3.5e-05 23.9 0.0 0.00031 20.8 0.0 2.5 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) PHM7_cyt PF14703.6 KIK69665.1 - 0.00045 20.5 3.8 4.2 7.6 0.0 5.1 5 0 0 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KIK69665.1 - 0.0011 19.0 1.4 0.58 10.2 0.0 4.6 5 0 0 5 5 5 1 RNA binding motif TPR_14 PF13428.6 KIK69665.1 - 0.0047 17.6 0.6 3.3 8.8 0.0 4.5 5 0 0 5 5 2 1 Tetratricopeptide repeat Nup35_RRM_2 PF14605.6 KIK69665.1 - 0.012 15.5 0.0 44 4.2 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif U3_assoc_6 PF08640.11 KIK69665.1 - 0.15 12.1 0.3 0.47 10.6 0.3 1.8 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 CR6_interact PF10147.9 KIK69665.1 - 2 8.1 6.1 0.62 9.7 0.5 2.7 2 1 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SKN1 PF03935.15 KIK69666.1 - 1.1e-205 683.9 4.5 1.2e-205 683.6 4.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) AAA_28 PF13521.6 KIK69666.1 - 0.051 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 KIK69667.1 - 1.3e-11 44.1 2.3 3.6e-11 42.8 0.8 2.6 2 0 0 2 2 2 1 F-box-like Mur_ligase_M PF08245.12 KIK69668.1 - 7.4e-08 32.6 0.0 2.5e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_18 PF12847.7 KIK69668.1 - 0.11 12.5 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain HD PF01966.22 KIK69668.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 HD domain Peptidase_C48 PF02902.19 KIK69669.1 - 1.4e-33 116.6 0.2 6.3e-19 68.7 0.4 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain CH PF00307.31 KIK69670.1 - 8e-49 164.4 0.1 4.9e-26 91.0 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KIK69670.1 - 8.9e-19 67.4 0.1 6e-18 64.7 0.0 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KIK69670.1 - 2.3e-13 49.8 0.1 6.9e-10 38.6 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KIK69670.1 - 0.00086 19.0 0.0 0.0072 16.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Spc7 PF08317.11 KIK69670.1 - 0.003 16.5 2.0 0.003 16.5 2.0 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein EF-hand_1 PF00036.32 KIK69670.1 - 0.0096 15.4 0.1 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 EF hand Spectrin PF00435.21 KIK69670.1 - 0.011 16.2 0.6 0.011 16.2 0.6 3.0 2 1 0 3 3 3 0 Spectrin repeat SF-assemblin PF06705.11 KIK69670.1 - 0.03 13.7 3.2 0.063 12.6 3.2 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin EF-hand_7 PF13499.6 KIK69670.1 - 0.045 14.2 0.4 0.2 12.2 0.4 2.2 1 1 0 1 1 1 0 EF-hand domain pair TolA_bind_tri PF16331.5 KIK69670.1 - 0.053 13.6 0.3 0.16 12.1 0.3 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation EF-hand_14 PF17959.1 KIK69670.1 - 0.071 13.5 0.3 8.9 6.7 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain Muted PF14942.6 KIK69670.1 - 0.21 11.9 2.2 1.5 9.2 2.2 2.3 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 KIK69670.1 - 0.25 10.9 1.5 0.52 9.8 1.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 KIK69670.1 - 1.2 9.2 6.0 0.31 11.1 0.8 2.6 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SSrecog PF03531.14 KIK69671.1 - 1.3e-26 92.3 0.2 4e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KIK69671.1 - 5.5e-22 78.0 0.8 5.4e-21 74.8 0.0 2.7 3 1 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 KIK69671.1 - 4e-21 75.2 0.4 3.3e-17 62.7 0.3 2.8 2 1 0 2 2 2 2 POB3-like N-terminal PH domain PH PF00169.29 KIK69672.1 - 0.00036 21.0 0.3 0.00092 19.7 0.3 1.7 1 0 0 1 1 1 1 PH domain Spt5_N PF11942.8 KIK69672.1 - 5.4 8.1 10.5 2.7 9.1 7.6 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.32 KIK69673.1 - 0.0025 18.6 1.7 0.0091 16.8 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat NAD_binding_10 PF13460.6 KIK69674.1 - 7.3e-11 42.3 0.0 3.3e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KIK69674.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69674.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3767 PF12597.8 KIK69675.1 - 3.2e-12 46.1 0.1 3.6e-12 46.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) PSI_PsaJ PF01701.18 KIK69675.1 - 0.015 15.8 2.3 0.02 15.4 2.0 1.4 1 1 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Rhodanese PF00581.20 KIK69676.1 - 3.3e-07 30.8 0.0 4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Staufen_C PF16482.5 KIK69676.1 - 0.0084 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Staufen C-terminal domain Robl_LC7 PF03259.17 KIK69677.1 - 1.2e-07 31.4 0.0 2.7e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain Alpha-L-AF_C PF06964.12 KIK69678.1 - 3.9e-35 121.5 0.2 1.1e-34 120.0 0.1 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Homeodomain PF00046.29 KIK69679.1 - 4.5e-05 23.2 1.1 0.00013 21.7 1.1 1.9 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KIK69680.1 - 9.5e-44 149.7 0.0 1.6e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69680.1 - 2.9e-18 66.1 0.0 5.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK69680.1 - 1.4e-05 24.6 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK69680.1 - 0.042 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family bMG1 PF17970.1 KIK69680.1 - 0.063 13.4 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain DUF4940 PF16298.5 KIK69680.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4940) Arylsulfotran_2 PF14269.6 KIK69681.1 - 3.4e-50 171.1 4.3 6.2e-50 170.3 4.3 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Serglycin PF04360.12 KIK69681.1 - 1.5 8.8 6.2 3.7 7.5 6.2 1.7 1 0 0 1 1 1 0 Serglycin Porin_3 PF01459.22 KIK69682.1 - 1.4e-68 231.3 2.3 1.7e-68 231.0 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rad60-SLD PF11976.8 KIK69684.1 - 3.8e-05 23.4 0.2 0.083 12.7 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.23 KIK69684.1 - 0.085 13.5 0.1 0.42 11.3 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain TTc_toxin_rep PF18807.1 KIK69685.1 - 0.017 14.9 0.3 0.037 13.8 0.3 1.5 1 0 0 1 1 1 0 Tripartite Tc toxins repeat EMP24_GP25L PF01105.24 KIK69685.1 - 0.07 13.1 0.3 2 8.3 0.1 2.9 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD ZapD PF07072.11 KIK69685.1 - 0.073 12.8 3.2 0.1 12.3 0.4 2.2 1 1 1 2 2 2 0 Cell division protein ALC PF17527.2 KIK69685.1 - 0.11 12.1 1.0 0.43 10.2 1.0 2.0 1 0 0 1 1 1 0 Phage ALC protein CENP-K PF11802.8 KIK69685.1 - 0.96 9.0 8.7 1.5 8.4 6.0 2.6 2 1 0 2 2 2 0 Centromere-associated protein K mRNA_triPase PF02940.15 KIK69686.1 - 8.9e-49 166.2 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain M60-like_N PF17291.2 KIK69686.1 - 0.004 17.0 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases F-box-like PF12937.7 KIK69688.1 - 8.8e-07 28.7 0.0 5.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK69688.1 - 0.29 11.6 3.9 3.7 8.1 0.1 3.9 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Profilin PF00235.19 KIK69689.1 - 5.6e-47 159.2 0.1 6.2e-47 159.0 0.1 1.0 1 0 0 1 1 1 1 Profilin ELFV_dehydrog PF00208.21 KIK69689.1 - 0.056 13.1 0.2 0.064 13.0 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ComX PF05952.12 KIK69689.1 - 0.059 13.3 0.2 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Mit_KHE1 PF10173.9 KIK69690.1 - 9.9e-58 195.4 0.7 1.2e-57 195.1 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related WD40 PF00400.32 KIK69691.1 - 5.1e-27 93.6 1.1 7.7e-07 29.7 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK69691.1 - 5.2e-09 36.3 0.0 0.04 14.2 0.0 4.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK69691.1 - 6.6e-05 21.7 0.1 0.0021 16.8 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK69691.1 - 0.00065 18.3 0.0 0.0016 17.0 0.0 1.8 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 KIK69691.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 KIK69691.1 - 0.012 14.9 0.0 0.73 9.1 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KIK69691.1 - 0.12 11.3 0.5 1.1 8.1 0.2 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Zn_clus PF00172.18 KIK69692.1 - 4.1e-05 23.6 6.8 8.2e-05 22.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nas2_N PF18265.1 KIK69692.1 - 0.019 14.8 0.0 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Nas2 N_terminal domain SMC_N PF02463.19 KIK69693.1 - 4.7e-27 94.9 0.3 1.2e-26 93.5 0.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK69693.1 - 1.2e-14 55.3 22.1 1.2e-14 55.3 22.1 6.1 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 KIK69693.1 - 3.1e-14 53.5 2.0 3.1e-14 53.5 2.0 3.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KIK69693.1 - 2.4e-07 30.9 0.8 0.00068 19.5 0.3 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK69693.1 - 0.0004 20.1 0.0 0.00099 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UvrA_DNA-bind PF17755.1 KIK69693.1 - 0.034 14.5 2.0 0.27 11.6 0.1 3.2 2 2 0 2 2 2 0 UvrA DNA-binding domain ABC_tran PF00005.27 KIK69693.1 - 0.092 13.3 0.1 0.092 13.3 0.1 6.6 4 2 0 4 4 4 0 ABC transporter HsbA PF12296.8 KIK69693.1 - 0.39 11.2 16.8 0.8 10.1 1.7 5.6 5 1 1 6 6 6 0 Hydrophobic surface binding protein A AAA_13 PF13166.6 KIK69693.1 - 2.6 6.6 82.5 3.1 6.3 39.5 5.3 4 2 1 5 5 5 0 AAA domain FA_desaturase PF00487.24 KIK69694.1 - 8.7e-16 58.5 26.6 1.5e-15 57.7 26.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK69694.1 - 4.1e-15 55.7 0.0 8.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SRF-TF PF00319.18 KIK69695.1 - 0.16 11.5 1.4 0.37 10.3 1.1 1.7 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Beta-APP PF03494.13 KIK69696.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) TMEM154 PF15102.6 KIK69696.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family E1_dh PF00676.20 KIK69697.1 - 4.6e-83 278.6 0.0 5.6e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component YcgR_2 PF12945.7 KIK69697.1 - 0.22 11.7 0.0 0.86 9.8 0.0 1.9 1 1 1 2 2 2 0 Flagellar protein YcgR Zip PF02535.22 KIK69698.1 - 1.8e-29 103.0 18.5 6.3e-29 101.2 18.5 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter HPP PF04982.13 KIK69698.1 - 0.13 12.5 3.4 0.26 11.5 0.2 2.5 2 1 0 2 2 2 0 HPP family DUF262 PF03235.14 KIK69699.1 - 2e-20 74.0 1.2 2.3e-19 70.5 1.2 2.3 1 1 0 1 1 1 1 Protein of unknown function DUF262 Ku_C PF03730.14 KIK69699.1 - 0.089 13.5 0.1 0.45 11.2 0.1 2.2 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm TPR_MLP1_2 PF07926.12 KIK69700.1 - 1.3e-30 106.1 46.0 4e-30 104.5 21.8 11.9 3 3 4 10 10 10 5 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KIK69700.1 - 0.00057 20.0 8.7 0.00057 20.0 8.7 12.7 4 3 9 13 13 13 5 Afadin- and alpha -actinin-Binding GAS PF13851.6 KIK69700.1 - 0.0023 17.3 5.4 0.0023 17.3 5.4 8.7 1 1 9 10 10 10 6 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KIK69700.1 - 0.0026 18.2 24.8 0.0026 18.2 24.8 7.8 1 1 6 8 8 8 2 Fez1 DUF2935 PF11155.8 KIK69701.1 - 0.043 14.2 0.0 3.7 7.9 0.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4407 PF14362.6 KIK69701.1 - 0.058 12.7 23.3 0.023 14.0 10.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lipoprotein_7 PF01540.16 KIK69701.1 - 0.061 12.6 12.2 0.39 10.0 12.2 2.0 1 1 0 1 1 1 0 Adhesin lipoprotein Fez1 PF06818.15 KIK69701.1 - 0.35 11.3 30.3 0.62 10.5 9.0 3.0 2 1 1 3 3 3 0 Fez1 DUF3347 PF11827.8 KIK69701.1 - 0.84 9.8 14.0 4.2 7.5 5.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Peptidase_C98 PF15499.6 KIK69701.1 - 1.2 8.6 4.2 18 4.7 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4735 PF15882.5 KIK69701.1 - 1.5 8.2 6.6 0.85 9.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) DUF2203 PF09969.9 KIK69701.1 - 2.5 8.8 20.1 2.6 8.8 3.1 3.5 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF3090 PF11290.8 KIK69701.1 - 7.3 6.4 10.4 2.9 7.7 5.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3090) TolA_bind_tri PF16331.5 KIK69702.1 - 0.002 18.2 9.2 0.002 18.2 9.2 1.9 1 1 1 2 2 2 1 TolA binding protein trimerisation THP2 PF09432.10 KIK69702.1 - 0.014 15.5 3.1 0.016 15.3 3.1 1.1 1 0 0 1 1 1 0 Tho complex subunit THP2 DUF948 PF06103.11 KIK69702.1 - 0.016 15.5 1.5 0.02 15.1 1.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) V-ATPase_G PF03179.15 KIK69702.1 - 0.023 15.2 5.7 0.028 14.9 5.7 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Laminin_II PF06009.12 KIK69702.1 - 0.043 13.8 3.6 0.049 13.7 3.6 1.1 1 0 0 1 1 1 0 Laminin Domain II FliT PF05400.13 KIK69702.1 - 0.12 13.2 7.4 0.14 13.0 7.4 1.1 1 0 0 1 1 1 0 Flagellar protein FliT DUF1664 PF07889.12 KIK69702.1 - 0.32 11.0 3.3 0.38 10.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ribosomal_S10 PF00338.22 KIK69703.1 - 4e-28 97.5 0.4 4.8e-28 97.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NT-C2 PF10358.9 KIK69704.1 - 3.4e-14 52.8 0.0 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Rib_recp_KP_reg PF05104.12 KIK69704.1 - 0.025 15.6 3.1 0.025 15.6 3.1 2.1 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region DUF3090 PF11290.8 KIK69704.1 - 0.11 12.3 0.1 0.63 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) 40S_SA_C PF16122.5 KIK69704.1 - 0.29 12.5 2.3 0.91 10.9 0.2 2.4 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus Ribosomal_L28 PF00830.19 KIK69706.1 - 2.1e-22 79.0 2.8 6.9e-22 77.4 3.2 1.7 2 0 0 2 2 2 1 Ribosomal L28 family GWT1 PF06423.12 KIK69707.1 - 4.3e-36 124.3 0.3 1.4e-35 122.6 0.0 2.1 2 1 0 2 2 2 1 GWT1 K_trans PF02705.16 KIK69708.1 - 8.8e-176 585.5 12.4 1.1e-175 585.2 12.4 1.1 1 0 0 1 1 1 1 K+ potassium transporter Mob1_phocein PF03637.17 KIK69709.1 - 1.7e-65 220.2 1.2 2.1e-65 219.8 1.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mob1_phocein PF03637.17 KIK69710.1 - 1.4e-62 210.7 1.6 1.7e-62 210.4 1.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF2990 PF11693.8 KIK69710.1 - 0.017 15.3 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Cpn60_TCP1 PF00118.24 KIK69711.1 - 6.4e-163 542.9 1.9 7.6e-163 542.6 1.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KIK69712.1 - 6.2e-50 170.0 0.0 1e-49 169.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69712.1 - 1.2e-23 83.8 0.0 3.1e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK69712.1 - 0.0023 16.8 0.1 0.004 16.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK69712.1 - 0.068 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KIK69712.1 - 0.09 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KIK69712.1 - 0.11 12.1 0.5 3.8 7.1 0.5 2.3 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 KIK69712.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3605 PF12239.8 KIK69713.1 - 3.4e-29 102.1 0.2 5.1e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) CSN8_PSD8_EIF3K PF10075.9 KIK69714.1 - 0.031 14.2 0.2 3.5 7.6 0.0 2.6 3 0 0 3 3 3 0 CSN8/PSMD8/EIF3K family LRR_6 PF13516.6 KIK69715.1 - 1.1e-13 50.0 10.7 0.54 10.4 0.0 7.8 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KIK69715.1 - 4.7e-09 36.4 13.8 0.27 11.7 3.5 5.9 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK69715.1 - 8.7e-05 22.6 7.9 1.6 9.5 0.0 6.3 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KIK69715.1 - 0.0019 17.9 15.6 1.4 8.8 5.8 5.4 5 1 0 5 5 5 2 Leucine rich repeat TbpB_B_D PF01298.18 KIK69715.1 - 0.0029 18.0 0.4 0.0068 16.8 0.4 1.6 1 0 0 1 1 1 1 C-lobe and N-lobe beta barrels of Tf-binding protein B LRR_2 PF07723.13 KIK69715.1 - 0.062 14.0 0.8 1.3 9.8 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat DUF2615 PF11027.8 KIK69716.1 - 1 9.5 0.0 1 9.5 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Zip PF02535.22 KIK69716.1 - 2.3 7.3 9.1 3.5 6.8 9.1 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Pex24p PF06398.11 KIK69717.1 - 6.7e-20 71.4 14.7 4.4e-13 49.0 1.7 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF3932 PF13068.6 KIK69718.1 - 0.69 10.2 3.1 0.98 9.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) POT1PC PF16686.5 KIK69719.1 - 1.7e-12 47.5 1.6 6.3e-06 26.1 0.1 3.7 3 1 0 3 3 3 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KIK69719.1 - 2.7e-12 46.7 0.0 1.5e-07 31.4 0.0 2.8 2 0 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 MFS_1 PF07690.16 KIK69720.1 - 5.1e-09 35.5 34.2 5.7e-09 35.4 30.8 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 KIK69720.1 - 4.9e-07 29.6 3.2 4.9e-07 29.6 3.2 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 LapA_dom PF06305.11 KIK69720.1 - 0.16 11.8 1.5 0.45 10.4 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain F-box-like PF12937.7 KIK69724.1 - 5.2e-08 32.7 0.2 5.2e-08 32.7 0.2 3.4 4 1 0 4 4 4 1 F-box-like F-box PF00646.33 KIK69724.1 - 0.011 15.6 3.0 0.022 14.6 1.2 2.5 2 0 0 2 2 2 0 F-box domain P33MONOX PF15302.6 KIK69727.1 - 0.0023 17.7 0.3 0.0034 17.2 0.3 1.3 1 1 0 1 1 1 1 P33 mono-oxygenase Voldacs PF03517.13 KIK69727.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling Syntaxin-6_N PF09177.11 KIK69728.1 - 0.019 15.5 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Cnn_1N PF07989.11 KIK69729.1 - 0.12 12.5 3.2 0.18 12.0 3.2 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Phos_pyr_kin PF08543.12 KIK69729.1 - 0.15 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DivIC PF04977.15 KIK69729.1 - 0.87 9.4 4.7 1.4 8.8 4.7 1.2 1 0 0 1 1 1 0 Septum formation initiator CxC4 PF18717.1 KIK69730.1 - 5.5e-42 142.7 6.0 7.1e-42 142.4 4.8 1.8 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases DUF3464 PF11947.8 KIK69736.1 - 5.8 6.7 6.5 0.83 9.4 1.4 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Zip PF02535.22 KIK69736.1 - 8.3 5.5 5.4 0.69 9.1 0.8 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter MTHFR PF02219.17 KIK69737.1 - 3.5e-107 358.0 0.0 5e-107 357.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase CENP-T_C PF15511.6 KIK69738.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK69738.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK69738.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK69738.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK69738.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK69738.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_hydro_17 PF00332.18 KIK69740.1 - 9.8e-10 38.5 3.7 1.1e-09 38.3 1.5 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 UCR_Fe-S_N PF10399.9 KIK69740.1 - 0.052 12.9 0.3 0.97 8.8 0.1 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal AAA_5 PF07728.14 KIK69742.1 - 3.4e-117 386.6 0.0 4.8e-21 75.2 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KIK69742.1 - 2.4e-45 153.1 12.8 1e-16 61.1 0.0 6.0 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KIK69742.1 - 7.3e-27 93.5 0.0 3.2e-26 91.4 0.0 2.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 KIK69742.1 - 6.2e-26 90.8 0.0 2.7e-09 37.0 0.0 8.1 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KIK69742.1 - 1.6e-21 77.1 0.1 0.00066 20.1 0.0 7.6 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK69742.1 - 4.3e-21 76.0 10.9 0.005 17.2 0.4 8.1 6 1 0 6 6 6 5 AAA ATPase domain AAA_7 PF12775.7 KIK69742.1 - 1.4e-20 73.5 2.2 0.0011 18.6 0.0 6.6 6 0 0 6 6 6 4 P-loop containing dynein motor region Dynein_heavy PF03028.15 KIK69742.1 - 1.5e-17 63.7 0.0 0.011 15.8 0.0 6.4 6 0 0 6 6 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 KIK69742.1 - 3.7e-15 56.0 0.0 0.044 13.5 0.0 5.7 7 0 0 7 7 5 4 Sigma-54 interaction domain AAA_6 PF12774.7 KIK69742.1 - 1.2e-14 54.1 0.0 0.18 10.7 0.0 7.2 7 0 0 7 7 7 4 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 KIK69742.1 - 1.4e-14 54.3 0.3 9e-05 22.3 0.0 7.1 8 0 0 8 8 6 2 AAA domain AAA_22 PF13401.6 KIK69742.1 - 5.9e-14 52.5 0.2 0.25 11.6 0.0 7.0 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.6 KIK69742.1 - 5.6e-13 49.1 0.0 0.028 14.5 0.0 6.6 8 0 0 8 8 6 3 AAA domain AAA_18 PF13238.6 KIK69742.1 - 9.7e-12 45.6 4.1 0.23 12.0 0.0 7.1 7 0 0 7 7 6 1 AAA domain AAA_28 PF13521.6 KIK69742.1 - 3.8e-10 40.2 2.7 0.39 10.9 0.0 6.3 5 0 0 5 5 5 2 AAA domain T2SSE PF00437.20 KIK69742.1 - 2e-09 36.9 2.1 0.099 11.7 0.0 6.2 6 0 0 6 6 6 1 Type II/IV secretion system protein TsaE PF02367.17 KIK69742.1 - 2.2e-09 37.4 1.5 0.82 9.7 0.0 6.1 6 0 0 6 6 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIK69742.1 - 2.3e-08 33.7 0.3 13 5.1 0.0 7.9 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KIK69742.1 - 6.6e-08 32.8 0.0 0.16 12.1 0.0 5.0 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_19 PF13245.6 KIK69742.1 - 3.3e-07 30.8 1.2 0.33 11.3 0.1 5.7 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.6 KIK69742.1 - 4.9e-07 30.0 0.5 1.4 9.1 0.0 6.1 6 0 0 6 6 5 1 AAA domain ABC_tran PF00005.27 KIK69742.1 - 6.1e-07 30.0 0.6 3.6 8.1 0.0 5.3 5 0 0 5 5 4 0 ABC transporter RNA_helicase PF00910.22 KIK69742.1 - 1.5e-06 28.6 0.1 9.5 6.7 0.0 6.3 6 0 0 6 6 5 0 RNA helicase DUF815 PF05673.13 KIK69742.1 - 1.3e-05 24.5 0.0 1.9 7.6 0.0 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KIK69742.1 - 1.7e-05 24.5 5.0 0.53 9.8 0.0 5.9 7 0 0 7 7 5 1 AAA domain NACHT PF05729.12 KIK69742.1 - 2.4e-05 24.3 2.6 5 7.0 0.0 5.8 5 0 0 5 5 5 0 NACHT domain IstB_IS21 PF01695.17 KIK69742.1 - 5.9e-05 22.9 0.2 0.49 10.1 0.0 4.8 5 0 0 5 5 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KIK69742.1 - 0.00011 21.6 0.0 23 4.2 0.0 6.3 7 0 0 7 7 7 0 Zeta toxin Roc PF08477.13 KIK69742.1 - 0.00016 21.9 1.4 7.5 6.8 0.0 5.1 6 0 0 6 6 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK69742.1 - 0.00017 21.3 3.0 8 6.3 0.0 5.5 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_8 PF12780.7 KIK69742.1 - 0.00025 20.4 0.1 0.59 9.4 0.0 4.6 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 RuvB_N PF05496.12 KIK69742.1 - 0.00031 20.5 1.6 5.1 6.8 0.0 5.3 5 0 0 5 5 4 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KIK69742.1 - 0.00075 19.5 0.3 21 5.0 0.0 5.4 6 0 0 6 6 5 0 Rad17 P-loop domain PduV-EutP PF10662.9 KIK69742.1 - 0.001 18.8 1.1 3.1 7.5 0.0 4.4 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KIK69742.1 - 0.0011 18.6 3.0 3.8 7.1 0.0 4.6 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain TIP49 PF06068.13 KIK69742.1 - 0.0021 17.3 1.1 3 7.0 0.0 4.3 5 0 0 5 5 5 1 TIP49 P-loop domain TniB PF05621.11 KIK69742.1 - 0.0031 17.0 0.0 5.8 6.3 0.0 4.6 4 0 0 4 4 4 0 Bacterial TniB protein AAA_11 PF13086.6 KIK69742.1 - 0.004 17.0 2.3 7.1 6.3 0.0 5.3 5 1 1 6 6 4 0 AAA domain RsgA_GTPase PF03193.16 KIK69742.1 - 0.0089 16.0 0.6 9.1 6.2 0.0 4.0 4 0 0 4 4 4 0 RsgA GTPase AAA_23 PF13476.6 KIK69742.1 - 0.0099 16.4 0.4 26 5.2 0.0 4.4 5 0 0 5 5 3 0 AAA domain DEAD PF00270.29 KIK69742.1 - 0.01 15.6 0.0 11 5.7 0.0 3.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase CPT PF07931.12 KIK69742.1 - 0.011 15.5 1.1 27 4.5 0.0 5.5 6 0 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 KIK69742.1 - 0.014 15.1 1.4 40 3.9 0.0 5.0 6 0 0 6 6 4 0 AAA domain MMR_HSR1 PF01926.23 KIK69742.1 - 0.015 15.4 0.8 11 6.1 0.0 4.5 5 0 0 5 5 3 0 50S ribosome-binding GTPase ResIII PF04851.15 KIK69742.1 - 0.017 15.2 0.0 11 5.9 0.0 3.9 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit dNK PF01712.19 KIK69742.1 - 0.034 14.0 0.1 12 5.7 0.0 3.5 3 0 0 3 3 3 0 Deoxynucleoside kinase PhoH PF02562.16 KIK69742.1 - 0.06 12.8 0.0 13 5.2 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein CbiA PF01656.23 KIK69742.1 - 0.076 13.1 0.0 12 6.0 0.0 3.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 KIK69742.1 - 0.11 12.0 5.9 30 4.1 0.0 5.3 6 1 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 KIK69742.1 - 0.17 11.2 1.9 35 3.6 0.1 4.1 5 0 0 5 5 5 0 DnaB-like helicase C terminal domain ATPase PF06745.13 KIK69742.1 - 0.18 11.1 0.1 39 3.5 0.0 3.3 3 0 0 3 3 3 0 KaiC NTPase_1 PF03266.15 KIK69742.1 - 0.27 11.1 6.8 42 4.0 0.2 5.3 5 0 0 5 5 5 0 NTPase IPT PF01745.16 KIK69742.1 - 0.29 10.5 1.3 12 5.2 0.0 3.2 4 0 0 4 4 2 0 Isopentenyl transferase RRM_1 PF00076.22 KIK69743.1 - 2e-15 56.3 0.0 2.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK69743.1 - 0.2 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ysc84 PF04366.12 KIK69744.1 - 1.4e-45 154.1 0.0 2.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 KIK69744.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Sec7 domain DUF1708 PF08101.11 KIK69745.1 - 6.3e-22 78.3 1.3 5.7e-20 71.9 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KIK69745.1 - 5.6e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Heme_oxygenase PF01126.20 KIK69746.1 - 2.9e-41 141.5 0.0 3.8e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-CCCH PF00642.24 KIK69747.1 - 5.6e-14 51.6 20.7 1.6e-05 24.7 3.1 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK69747.1 - 3.8e-09 36.3 26.3 0.00059 19.8 7.5 4.0 3 1 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 KIK69747.1 - 3e-07 30.1 23.7 0.006 16.4 1.7 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 KIK69747.1 - 3.7e-07 30.8 13.6 0.055 14.2 1.0 3.5 2 1 1 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 KIK69747.1 - 8.9e-06 25.9 4.3 0.0023 18.1 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf-RING_2 PF13639.6 KIK69748.1 - 1.4e-11 44.5 4.4 2.8e-11 43.6 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIK69748.1 - 1.5e-10 40.7 4.3 3.1e-10 39.6 4.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 KIK69748.1 - 2.5e-07 30.6 0.0 5.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KIK69748.1 - 5e-06 26.4 2.5 8.5e-06 25.6 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK69748.1 - 1e-05 25.3 4.4 2.1e-05 24.3 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK69748.1 - 2.5e-05 24.1 3.1 4.9e-05 23.1 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK69748.1 - 5.1e-05 23.5 7.0 0.00024 21.3 7.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KIK69748.1 - 6.9e-05 22.6 2.2 0.00013 21.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK69748.1 - 0.00042 20.3 4.3 0.0032 17.5 0.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIK69748.1 - 0.002 18.1 2.9 0.002 18.1 2.9 2.3 3 1 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KIK69748.1 - 0.011 15.6 3.3 0.011 15.6 3.3 1.7 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 SLATT_3 PF18184.1 KIK69748.1 - 0.034 14.3 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Vps39_2 PF10367.9 KIK69748.1 - 0.24 11.9 4.1 0.68 10.4 0.4 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.8 KIK69748.1 - 0.24 11.6 3.7 1.4 9.1 3.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KIK69748.1 - 0.42 10.3 3.7 0.85 9.3 3.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Fungal_trans PF04082.18 KIK69750.1 - 1.5e-18 66.8 0.0 3.9e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK69750.1 - 2.1e-05 24.5 13.9 3.9e-05 23.7 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5055 PF16478.5 KIK69750.1 - 0.2 11.9 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5055) Phosphodiest PF01663.22 KIK69751.1 - 1.1e-76 258.8 1.7 1.4e-76 258.5 1.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIK69751.1 - 0.0047 16.4 0.0 0.79 9.0 0.0 2.3 2 0 0 2 2 2 2 Sulfatase PHY PF00360.20 KIK69752.1 - 8e-29 100.2 0.0 1.4e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KIK69752.1 - 5.9e-21 75.1 0.0 1.6e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK69752.1 - 3.5e-17 62.6 0.1 1.5e-16 60.6 0.1 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KIK69752.1 - 7e-15 55.8 0.0 2e-13 51.1 0.0 2.7 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 KIK69752.1 - 3.7e-10 39.7 0.8 1.2e-09 38.0 0.8 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KIK69752.1 - 9.7e-10 39.1 0.0 3.3e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KIK69752.1 - 0.057 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 KIK69753.1 - 3.9e-45 153.7 0.2 4.8e-45 153.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69753.1 - 4.1e-34 118.2 0.1 5e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69753.1 - 8.4e-10 38.9 0.0 2.8e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK69753.1 - 0.00036 20.1 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIK69753.1 - 0.00048 19.6 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KIK69753.1 - 0.00074 19.0 0.0 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK69753.1 - 0.0092 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KIK69753.1 - 0.037 13.4 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CBFD_NFYB_HMF PF00808.23 KIK69754.1 - 1.3e-15 57.4 1.4 1.4e-15 57.3 0.3 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK69754.1 - 1.2e-08 35.4 0.3 1.8e-08 34.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK69754.1 - 0.037 14.1 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Pro-kuma_activ PF09286.11 KIK69755.1 - 3.4e-38 131.1 0.0 7.3e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK69755.1 - 3e-09 36.6 5.1 4.2e-09 36.1 5.1 1.2 1 0 0 1 1 1 1 Subtilase family ProSAAS PF07259.12 KIK69755.1 - 0.054 13.5 0.1 16 5.4 0.2 2.5 2 0 0 2 2 2 0 ProSAAS precursor Asp PF00026.23 KIK69756.1 - 1.1e-19 71.0 8.8 1.9e-17 63.7 8.8 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KIK69756.1 - 0.0038 17.8 0.3 0.12 13.0 0.1 2.6 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK69756.1 - 0.0042 17.7 0.2 0.018 15.6 0.2 2.2 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 KIK69756.1 - 0.006 16.8 5.0 0.21 11.8 2.2 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Orthoreo_P10 PF07204.11 KIK69756.1 - 0.066 13.2 0.4 0.34 10.9 0.4 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Asp PF00026.23 KIK69757.1 - 1.6e-20 73.8 9.7 5.1e-18 65.5 9.7 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIK69757.1 - 2.4e-06 28.1 3.2 0.007 17.0 0.7 3.6 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK69757.1 - 2.6e-06 27.9 0.2 0.18 12.4 0.1 3.9 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Glycophorin_A PF01102.18 KIK69757.1 - 0.088 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A MGC-24 PF05283.11 KIK69757.1 - 0.67 10.4 2.2 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Aminotran_1_2 PF00155.21 KIK69758.1 - 1.5e-23 83.6 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIK69758.1 - 2.5e-12 46.3 0.0 3.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Dynactin_p62 PF05502.13 KIK69759.1 - 6e-73 246.2 6.0 5.2e-45 154.1 3.6 2.1 2 0 0 2 2 2 2 Dynactin p62 family zf-4CXXC_R1 PF10497.9 KIK69759.1 - 2.4 8.4 9.2 1.8 8.8 6.6 2.0 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Abhydrolase_3 PF07859.13 KIK69762.1 - 3.5e-14 53.2 0.0 3.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK69762.1 - 5.8e-10 39.0 0.2 3.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIK69762.1 - 1.4e-06 28.1 0.0 2.6e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69762.1 - 2.1e-06 28.5 0.3 3.1e-06 28.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK69762.1 - 3.2e-06 26.8 0.0 0.0029 17.2 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIK69762.1 - 0.0038 17.1 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK69762.1 - 0.012 14.5 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family LIP PF03583.14 KIK69762.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase DUF3072 PF11272.8 KIK69762.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) ExoD PF06055.12 KIK69762.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Lipase_GDSL PF00657.22 KIK69763.1 - 3.8e-08 33.5 0.0 9.3e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK69763.1 - 3.2e-06 27.7 0.1 1.6e-05 25.4 0.2 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Gelsolin PF00626.22 KIK69764.1 - 1.5e-34 117.7 0.0 4.1e-17 61.8 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat DNA_pol_B_thumb PF14791.6 KIK69765.1 - 4.4e-14 52.4 0.0 9.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH PF00633.23 KIK69765.1 - 8.3e-08 31.7 0.0 5.6e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_pol_B_palm PF14792.6 KIK69765.1 - 5.1e-07 29.9 0.0 7.8e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.6 KIK69765.1 - 2.7e-05 24.7 0.0 5.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_8 PF14716.6 KIK69765.1 - 8.2e-05 22.9 0.2 0.59 10.5 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain Cdd1 PF11731.8 KIK69765.1 - 9.1e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KIK69765.1 - 0.00035 20.3 0.0 0.00086 19.1 0.0 1.7 1 1 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_3 PF12836.7 KIK69765.1 - 0.0071 16.6 0.0 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KIK69765.1 - 0.01 16.4 0.0 0.058 14.0 0.0 2.0 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Methyltransf_23 PF13489.6 KIK69766.1 - 5.7e-18 65.3 0.0 8.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK69766.1 - 1.4e-13 51.2 0.1 1e-12 48.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK69766.1 - 1.9e-13 50.9 0.1 2.3e-11 44.3 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK69766.1 - 8.3e-11 42.5 0.0 4.4e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69766.1 - 4.9e-10 39.4 0.0 9.4e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIK69766.1 - 0.004 17.0 0.1 0.0083 16.0 0.0 1.5 2 0 0 2 2 2 1 Hypothetical methyltransferase FtsJ PF01728.19 KIK69766.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KIK69766.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIK69766.1 - 0.02 14.2 0.0 0.16 11.3 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 KIK69766.1 - 0.02 14.3 0.0 0.07 12.6 0.0 1.8 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 KIK69766.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KIK69766.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CodY PF06018.14 KIK69766.1 - 0.038 13.5 0.0 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 CodY GAF-like domain DREV PF05219.12 KIK69766.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Adeno_100 PF02438.16 KIK69766.1 - 0.13 10.4 0.0 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Late 100kD protein OPA3 PF07047.12 KIK69768.1 - 5.3e-44 149.0 0.3 9.3e-44 148.2 0.3 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2884 PF11101.8 KIK69768.1 - 0.013 15.0 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) SOAR PF16533.5 KIK69768.1 - 0.016 15.2 2.2 0.018 15.0 1.0 1.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region Ax_dynein_light PF10211.9 KIK69768.1 - 0.023 14.6 1.2 0.023 14.6 1.2 1.5 2 0 0 2 2 2 0 Axonemal dynein light chain CLZ PF16526.5 KIK69768.1 - 0.061 13.7 3.1 0.082 13.3 0.9 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-CCHH PF10283.9 KIK69769.1 - 0.0031 17.5 2.2 0.0064 16.5 2.2 1.6 1 0 0 1 1 1 1 PBZ domain MBOAT PF03062.19 KIK69770.1 - 6.6e-51 173.7 23.8 9.7e-51 173.1 23.8 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-CCHH PF10283.9 KIK69771.1 - 0.0025 17.8 2.1 0.0056 16.6 2.1 1.6 1 0 0 1 1 1 1 PBZ domain WD40 PF00400.32 KIK69772.1 - 8.3e-13 48.6 2.2 0.00017 22.3 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK69772.1 - 0.1 12.9 0.0 0.58 10.5 0.0 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Q_salvage PF10343.9 KIK69773.1 - 1.3e-89 300.5 0.0 1.7e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family 4HBT_3 PF13622.6 KIK69774.1 - 1e-23 84.9 0.0 1.3e-23 84.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DHHC PF01529.20 KIK69775.1 - 5.3e-35 120.4 7.9 5.3e-35 120.4 7.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1272 PF06906.11 KIK69775.1 - 0.89 9.7 4.8 2 8.6 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Yip1 PF04893.17 KIK69775.1 - 1.2 8.9 8.1 0.43 10.3 3.2 2.1 2 0 0 2 2 2 0 Yip1 domain Phtf-FEM1B_bdg PF12129.8 KIK69775.1 - 2.5 7.9 5.0 0.87 9.4 1.5 1.8 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor ABC_export PF16962.5 KIK69775.1 - 3.9 5.8 12.2 0.39 9.1 4.5 2.2 2 1 0 2 2 2 0 Putative ABC exporter Methyltransf_33 PF10017.9 KIK69776.1 - 3.5e-72 243.2 0.1 1.6e-71 241.0 0.1 1.8 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KIK69776.1 - 1.1e-22 80.8 1.5 7.3e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIK69776.1 - 0.00023 21.7 1.2 0.00045 20.7 0.4 1.9 2 0 0 2 2 2 1 DinB superfamily HA2 PF04408.23 KIK69778.1 - 8.2e-21 74.3 0.0 1.7e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK69778.1 - 9.9e-12 45.2 0.0 3.1e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIK69778.1 - 2.1e-10 40.8 0.0 5.1e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KIK69778.1 - 1.1e-05 25.7 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KIK69778.1 - 1.1e-05 25.3 0.1 2.9e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KIK69778.1 - 0.0024 18.2 0.1 0.005 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK69778.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIK69778.1 - 0.035 13.5 0.0 0.098 12.0 0.0 1.8 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KIK69778.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KIK69778.1 - 0.11 12.9 0.1 0.98 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KIK69778.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 KIK69778.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 KIK69778.1 - 0.13 12.8 0.1 0.47 11.0 0.1 2.0 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIK69778.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Asp PF00026.23 KIK69779.1 - 2.2e-30 106.1 15.6 7.1e-29 101.2 15.6 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK69779.1 - 0.00072 19.8 6.9 0.0065 16.7 1.6 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK69779.1 - 0.0091 16.6 4.1 0.059 14.0 0.4 3.3 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK69779.1 - 0.037 14.6 1.0 0.39 11.3 0.1 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KIK69780.1 - 2.6e-41 142.1 13.6 4.3e-41 141.4 13.6 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK69780.1 - 1.5e-05 25.3 4.0 0.032 14.5 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK69780.1 - 0.0013 19.3 4.4 0.033 14.8 0.2 3.1 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK69780.1 - 0.0054 17.3 1.1 0.09 13.4 0.0 2.9 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease ORC6 PF05460.13 KIK69781.1 - 0.017 14.4 10.6 0.053 12.8 0.1 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Avl9 PF09794.9 KIK69782.1 - 8.7e-120 399.9 0.0 1.8e-119 398.9 0.0 1.5 2 0 0 2 2 2 1 Transport protein Avl9 DUF2347 PF09804.9 KIK69782.1 - 9e-10 38.6 0.9 0.0033 17.1 0.0 3.5 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KIK69782.1 - 8.4e-08 32.2 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis zf-MYND PF01753.18 KIK69783.1 - 3.9e-09 36.5 5.7 3.9e-09 36.5 5.7 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KIK69783.1 - 0.023 14.8 2.7 0.07 13.2 2.7 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_S28 PF05577.12 KIK69784.1 - 6.1e-53 180.2 0.0 9e-42 143.4 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 BTB PF00651.31 KIK69785.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Herpes_UL33 PF03581.13 KIK69785.1 - 0.17 12.3 1.0 0.69 10.3 0.3 2.2 2 0 0 2 2 2 0 Herpesvirus UL33-like protein SR-25 PF10500.9 KIK69785.1 - 5.5 6.5 10.9 11 5.5 10.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YjeF_N PF03853.15 KIK69786.1 - 1.6e-37 129.0 0.0 2e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF3493 PF11998.8 KIK69787.1 - 0.031 14.4 3.7 5.8 7.1 0.0 2.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 CbtA PF09490.10 KIK69787.1 - 0.26 11.0 5.6 1.8 8.3 4.4 2.6 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtA) Sin3a_C PF16879.5 KIK69789.1 - 1.2e-75 254.9 0.0 4.3e-74 249.8 0.0 3.2 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KIK69789.1 - 7.5e-37 125.2 1.1 1.5e-18 66.6 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KIK69789.1 - 2.3e-31 107.7 4.4 6.8e-29 99.8 4.4 2.8 1 1 0 1 1 1 1 Sin3 family co-repressor AAA PF00004.29 KIK69790.1 - 5.2e-44 149.9 0.0 9.6e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK69790.1 - 1.2e-11 44.2 0.1 3.2e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIK69790.1 - 2e-08 34.6 0.0 5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KIK69790.1 - 3e-07 30.3 0.2 6.6e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KIK69790.1 - 2.2e-06 27.7 0.0 8.1e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK69790.1 - 8e-06 26.3 0.1 8.9e-05 22.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK69790.1 - 1.1e-05 25.8 0.2 0.0053 17.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK69790.1 - 5.7e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIK69790.1 - 0.00041 20.9 0.4 0.017 15.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KIK69790.1 - 0.00094 18.5 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIK69790.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK69790.1 - 0.0019 17.9 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KIK69790.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIK69790.1 - 0.0061 16.0 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KIK69790.1 - 0.0081 15.6 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2072 PF09845.9 KIK69790.1 - 0.0084 16.4 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein AAA_28 PF13521.6 KIK69790.1 - 0.01 16.1 0.3 0.022 15.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KIK69790.1 - 0.012 15.3 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KIK69790.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KIK69790.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KIK69790.1 - 0.02 14.6 0.0 0.1 12.3 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 KIK69790.1 - 0.026 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIK69790.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KIK69790.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KIK69790.1 - 0.037 12.7 0.1 1.7 7.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK69790.1 - 0.041 14.3 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DivIC PF04977.15 KIK69790.1 - 0.059 13.1 0.5 0.18 11.6 0.5 1.8 1 0 0 1 1 1 0 Septum formation initiator Parvo_NS1 PF01057.17 KIK69790.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIK69790.1 - 0.067 12.8 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK69790.1 - 0.092 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KIK69790.1 - 0.12 12.7 0.1 0.59 10.5 0.1 2.1 3 0 0 3 3 1 0 AAA domain AAA_11 PF13086.6 KIK69790.1 - 0.12 12.1 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF5406 PF17400.2 KIK69790.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5406) ABC_tran PF00005.27 KIK69790.1 - 0.14 12.7 0.1 0.87 10.1 0.0 2.3 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 KIK69790.1 - 0.15 12.0 0.0 0.69 9.8 0.0 2.0 1 1 0 2 2 2 0 NACHT domain IMS PF00817.20 KIK69791.1 - 1.1e-41 142.3 0.0 2.5e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KIK69791.1 - 2.8e-20 72.5 6.5 2.8e-20 72.5 6.5 1.8 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KIK69791.1 - 6.7e-15 55.8 0.0 8.8e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KIK69791.1 - 3.5e-10 40.2 0.0 8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK69791.1 - 2.4e-06 27.9 0.0 5.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KIK69791.1 - 0.0005 20.3 0.0 0.0019 18.4 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.7 KIK69791.1 - 0.00081 19.3 0.1 0.0016 18.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain UBM PF14377.6 KIK69791.1 - 0.0033 16.8 0.3 0.37 10.3 0.1 2.8 2 0 0 2 2 2 1 Ubiquitin binding region DUF1805 PF08827.11 KIK69791.1 - 0.023 15.0 0.1 0.055 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) mCpol PF18182.1 KIK69791.1 - 0.023 15.0 0.0 0.072 13.4 0.0 1.8 1 0 0 1 1 1 0 minimal CRISPR polymerase domain KxDL PF10241.9 KIK69791.1 - 0.087 13.1 1.4 13 6.2 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Glyco_transf_90 PF05686.12 KIK69792.1 - 3.2e-08 32.9 0.6 3.3e-07 29.6 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 90 FMO-like PF00743.19 KIK69793.1 - 1.8e-11 43.2 0.3 1.3e-10 40.3 0.3 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK69793.1 - 1.2e-10 41.0 0.0 2.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK69793.1 - 9.1e-09 35.4 0.0 9.8e-08 32.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK69793.1 - 0.00055 19.3 0.1 0.013 14.7 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK69793.1 - 0.0062 16.2 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK69793.1 - 0.1 11.8 0.0 9.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK69793.1 - 0.18 11.8 0.0 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2070 PF09843.9 KIK69794.1 - 0.015 13.6 3.9 0.016 13.5 3.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 KIK69796.1 - 8.7e-13 48.5 9.0 1.2e-12 48.1 9.0 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1905 PF08922.11 KIK69796.1 - 0.14 12.2 0.0 2.2 8.4 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1905) DNA_mis_repair PF01119.19 KIK69797.1 - 3.5e-21 75.1 0.0 7.7e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 KIK69797.1 - 3.5e-17 62.5 1.9 6e-12 45.6 0.3 3.0 3 0 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 KIK69797.1 - 9.3e-15 54.7 0.5 3.1e-14 53.0 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK69797.1 - 1.6e-08 35.0 0.1 5.1e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RMMBL PF07521.12 KIK69797.1 - 0.12 12.3 0.0 2.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain DUF5506 PF17611.2 KIK69799.1 - 0.067 13.1 0.0 0.074 13.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5506) Ribonuc_red_lgC PF02867.15 KIK69800.1 - 1.2e-182 608.1 0.0 1.7e-182 607.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KIK69800.1 - 1.7e-24 85.6 0.1 4.4e-24 84.3 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KIK69800.1 - 2e-16 60.3 0.2 6.4e-16 58.7 0.2 1.9 1 0 0 1 1 1 1 ATP cone domain RNA_pol_inhib PF16857.5 KIK69801.1 - 0.086 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase inhibitor SSFA2_C PF14723.6 KIK69801.1 - 0.44 10.4 3.7 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Aldo_ket_red PF00248.21 KIK69802.1 - 3.2e-35 121.8 0.1 1.7e-29 103.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family AMPK1_CBM PF16561.5 KIK69803.1 - 4.3e-16 58.9 0.0 1e-12 48.1 0.0 2.6 3 0 0 3 3 3 2 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KIK69804.1 - 3.5e-21 75.3 0.4 4.4e-21 74.9 0.4 1.5 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Cofilin_ADF PF00241.20 KIK69805.1 - 5.7e-18 64.9 0.0 7.2e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.9 KIK69805.1 - 0.029 14.3 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Prenyltrans PF00432.21 KIK69806.1 - 6.9e-31 105.7 11.9 7.8e-08 31.9 0.4 5.9 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Fungal_trans PF04082.18 KIK69807.1 - 8.1e-25 87.3 0.1 1.8e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK69807.1 - 0.038 14.1 9.2 0.072 13.2 9.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRS1 PF04939.12 KIK69808.1 - 4.7e-60 202.1 2.5 4.7e-60 202.1 2.5 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) BHD_3 PF10405.9 KIK69809.1 - 9.9e-30 102.8 0.1 2e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KIK69809.1 - 3.4e-21 75.5 0.0 1.2e-20 73.7 0.0 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KIK69809.1 - 1.6e-16 59.8 0.2 1.6e-15 56.6 0.2 2.5 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KIK69809.1 - 1.1e-13 51.8 0.1 1.1e-13 51.8 0.1 4.0 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KIK69809.1 - 8.1e-07 29.5 0.1 1e-05 26.0 0.1 2.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily E3_binding PF02817.17 KIK69809.1 - 8.2 6.9 6.7 0.76 10.2 0.4 2.6 3 0 0 3 3 3 0 e3 binding domain GCD14 PF08704.10 KIK69810.1 - 1.4e-54 185.4 0.1 5.7e-52 176.8 0.1 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GCD14 PF08704.10 KIK69811.1 - 7.1e-21 75.0 0.0 8.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KIK69811.1 - 0.00042 20.1 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PAS_3 PF08447.12 KIK69812.1 - 7.6e-10 39.0 0.0 2.6e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KIK69812.1 - 3.7e-05 23.7 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KIK69812.1 - 0.00048 20.2 0.1 0.03 14.5 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS_9 PF13426.7 KIK69812.1 - 0.0058 16.9 0.0 1 9.7 0.0 2.6 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.10 KIK69812.1 - 0.0065 16.7 0.0 0.036 14.3 0.0 2.1 2 0 0 2 2 2 1 PAS fold Phage_C PF12025.8 KIK69812.1 - 0.12 12.2 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Phage protein C Melibiase_2 PF16499.5 KIK69813.1 - 1.3e-55 188.6 0.0 2.3e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIK69813.1 - 2.8e-11 43.3 0.1 6.5e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIK69813.1 - 0.0009 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_30C PF17189.4 KIK69813.1 - 0.091 13.0 1.3 0.2 11.9 0.2 2.1 2 1 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain FYRN PF05964.14 KIK69814.1 - 3.1e-18 65.3 0.8 5.4e-18 64.6 0.8 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KIK69814.1 - 1.8e-14 53.6 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 F/Y rich C-terminus Ras PF00071.22 KIK69815.1 - 2.7e-39 134.4 0.0 4.7e-38 130.3 0.0 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KIK69815.1 - 4.1e-28 98.0 0.0 7.2e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK69815.1 - 2e-07 30.7 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK69815.1 - 4.2e-06 26.3 0.1 1.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK69815.1 - 0.0016 18.0 0.0 0.0074 15.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK69815.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase A_deaminase PF00962.22 KIK69816.1 - 2.4e-121 405.1 0.2 3.2e-121 404.7 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 KIK69817.1 - 3e-19 69.4 0.0 5.3e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69817.1 - 2e-07 30.6 0.0 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK69817.1 - 0.00022 20.1 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK69817.1 - 0.0037 17.2 0.1 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF722 PF05263.11 KIK69818.1 - 0.0083 16.3 0.8 0.013 15.7 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF722) BEX PF04538.12 KIK69818.1 - 0.0087 16.7 0.3 0.019 15.6 0.3 1.7 1 1 0 1 1 1 1 Brain expressed X-linked like family UPF0515 PF15135.6 KIK69818.1 - 0.016 14.6 2.7 0.021 14.2 1.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Lip_prot_lig_C PF10437.9 KIK69818.1 - 0.06 13.3 1.5 13 5.8 0.1 2.7 1 1 2 3 3 3 0 Bacterial lipoate protein ligase C-terminus GAS PF13851.6 KIK69818.1 - 0.079 12.3 11.1 0.014 14.7 7.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KIK69818.1 - 0.11 12.7 5.6 2.2 8.5 2.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 KIK69818.1 - 0.18 11.6 4.2 0.1 12.5 2.2 1.7 2 0 0 2 2 2 0 Sec34-like family XhlA PF10779.9 KIK69818.1 - 0.38 11.0 11.2 0.37 11.0 2.5 3.4 3 0 0 3 3 3 0 Haemolysin XhlA DUF745 PF05335.13 KIK69818.1 - 0.44 10.3 5.1 1.5 8.5 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PspB PF06667.12 KIK69818.1 - 0.45 10.6 6.0 2.9 8.0 0.7 3.4 2 1 1 3 3 3 0 Phage shock protein B DHR10 PF18595.1 KIK69818.1 - 0.66 10.0 12.4 1.9 8.6 8.7 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain LMBR1 PF04791.16 KIK69818.1 - 0.78 8.6 2.4 0.85 8.5 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 KIK69818.1 - 1.1 7.7 3.0 1.6 7.1 3.0 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 KIK69818.1 - 1.3 9.2 11.9 0.16 12.2 6.1 2.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.11 KIK69818.1 - 4.8 7.0 16.0 1.9 8.3 6.1 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 MFS_1 PF07690.16 KIK69819.1 - 2.9e-24 85.7 24.9 2.9e-24 85.7 24.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KIK69820.1 - 1.1e-18 67.3 2.8 1.4e-18 66.9 0.8 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK69820.1 - 6.8e-10 38.9 11.3 1.1e-09 38.2 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 KIK69821.1 - 1.4e-18 67.1 0.0 4.2e-17 62.4 0.0 2.0 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Pkinase PF00069.25 KIK69822.1 - 1.1e-63 215.1 0.0 2.3e-63 214.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69822.1 - 3.3e-34 118.4 0.0 7.2e-34 117.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KIK69822.1 - 0.0052 15.9 0.1 0.011 14.8 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KIK69822.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK69822.1 - 0.056 13.0 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIK69822.1 - 0.058 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Laminin_II PF06009.12 KIK69823.1 - 2.1 8.3 9.2 0.44 10.5 3.0 2.2 1 1 1 2 2 2 0 Laminin Domain II JIP_LZII PF16471.5 KIK69823.1 - 2.4 8.4 12.3 0.37 11.0 7.2 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II MFS_1 PF07690.16 KIK69824.1 - 1.7e-22 79.8 53.1 4.6e-12 45.5 24.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK69824.1 - 1.7e-19 70.0 15.8 1.9e-18 66.6 0.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Ebp2 PF05890.12 KIK69825.1 - 5.1e-84 282.0 8.6 8.1e-84 281.3 8.6 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 TEX19 PF15553.6 KIK69825.1 - 3.2 7.7 4.9 11 6.0 4.4 2.0 2 0 0 2 2 2 0 Testis-expressed protein 19 Cullin PF00888.22 KIK69826.1 - 3.3e-19 68.9 0.1 6.2e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KIK69826.1 - 1.4e-13 51.1 0.1 1e-12 48.4 0.0 2.6 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 YTH PF04146.15 KIK69827.1 - 6.8e-63 211.5 0.0 1.6e-62 210.3 0.0 1.7 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KIK69827.1 - 4.1e-07 29.7 0.0 7.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 KIK69828.1 - 5e-21 75.3 0.0 1.7e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK69828.1 - 1.4e-15 57.6 0.0 3.4e-13 49.9 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIK69828.1 - 1.7e-08 35.1 0.2 1.7e-08 35.1 0.2 2.0 2 0 0 2 2 2 1 RecQ zinc-binding DUF2235 PF09994.9 KIK69829.1 - 1.2e-89 300.5 0.0 1.5e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SH3_9 PF14604.6 KIK69830.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mito_fiss_reg PF05308.11 KIK69830.1 - 0.59 10.2 0.0 0.59 10.2 0.0 3.1 3 1 0 3 3 3 0 Mitochondrial fission regulator Sugar_tr PF00083.24 KIK69831.1 - 1.1e-71 242.1 19.2 4.6e-70 236.7 19.2 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK69831.1 - 3.6e-23 82.1 25.8 1e-17 64.1 5.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HAD_2 PF13419.6 KIK69832.1 - 1.3e-15 57.9 0.0 1.3e-10 41.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK69832.1 - 7.5e-12 46.0 0.0 3e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK69832.1 - 4.3e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like PKcGMP_CC PF16808.5 KIK69834.1 - 0.044 13.6 12.5 2.4 8.1 1.9 3.7 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KIK69834.1 - 0.047 12.6 9.0 0.075 11.9 9.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KIK69834.1 - 0.15 11.4 5.3 0.2 10.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 KIK69834.1 - 0.27 11.2 14.7 1.7 8.7 1.9 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF641 PF04859.12 KIK69834.1 - 1.1 9.6 10.1 11 6.4 9.3 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) AAA_23 PF13476.6 KIK69834.1 - 1.2 9.6 8.3 1.6 9.2 8.3 1.2 1 0 0 1 1 1 0 AAA domain LRRFIP PF09738.9 KIK69834.1 - 1.2 8.5 12.0 3.7 6.9 12.0 1.7 1 1 0 1 1 1 0 LRRFIP family Csm1_N PF18504.1 KIK69834.1 - 1.9 8.9 13.9 7.8 6.9 5.2 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KIK69834.1 - 2.2 8.3 12.9 3.7 7.6 7.5 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 KIK69834.1 - 3.3 8.2 8.2 3.6 8.1 7.0 1.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 KIK69834.1 - 6.3 6.9 12.6 5.4 7.1 5.0 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding MetOD2 PF18548.1 KIK69834.1 - 8.6 6.6 8.9 5.4 7.2 0.8 3.0 1 1 2 3 3 3 0 Metanogen output domain 2 Peptidase_U32_C PF16325.5 KIK69836.1 - 0.086 13.1 0.0 0.098 12.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain KDZ PF18758.1 KIK69838.1 - 6.9e-08 32.4 0.1 7.3e-08 32.3 0.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase BLOC1S3 PF15753.5 KIK69842.1 - 0.013 15.7 0.9 0.033 14.3 0.4 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4927 PF16279.5 KIK69843.1 - 0.046 14.7 0.1 0.051 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4927) ACTH_assoc PF16102.5 KIK69846.1 - 0.25 12.2 0.7 0.25 12.2 0.7 2.4 2 0 0 2 2 2 0 ACTH-associated domain Mito_fiss_reg PF05308.11 KIK69847.1 - 0.11 12.6 4.3 0.15 12.1 4.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SR-25 PF10500.9 KIK69847.1 - 0.28 10.8 8.2 0.32 10.6 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GTF2I PF02946.14 KIK69848.1 - 0.00089 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 GTF2I-like repeat Med7 PF05983.11 KIK69850.1 - 0.033 14.3 0.7 0.061 13.4 0.7 1.3 1 0 0 1 1 1 0 MED7 protein PTS_IIA PF02255.16 KIK69850.1 - 0.12 12.5 1.1 0.19 11.8 1.1 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit KDZ PF18758.1 KIK69852.1 - 1.2e-69 234.3 0.1 1.9e-69 233.7 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK69852.1 - 0.00021 21.4 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK69852.1 - 0.00043 20.1 0.1 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases CpXC PF14353.6 KIK69852.1 - 0.44 10.6 1.9 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 CpXC protein HGD-D PF06050.13 KIK69853.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.3 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Sec20 PF03908.13 KIK69853.1 - 0.023 14.6 0.1 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 Sec20 Cwf_Cwc_15 PF04889.12 KIK69853.1 - 0.1 12.3 5.0 0.16 11.7 5.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Asp_protease_2 PF13650.6 KIK69854.1 - 0.074 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 KIK69856.1 - 6.4e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KIK69856.1 - 9.9e-05 22.2 1.3 0.0003 20.7 1.3 1.9 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 KIK69856.1 - 0.0014 19.3 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_6 PF15288.6 KIK69856.1 - 0.0022 17.8 0.1 0.0052 16.6 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KIK69856.1 - 0.029 14.9 0.0 0.08 13.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Poly_export PF02563.16 KIK69856.1 - 0.039 14.2 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein Mt_ATP-synt_D PF05873.12 KIK69857.1 - 0.085 12.7 0.9 0.36 10.7 0.1 2.1 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Baculo_PEP_C PF04513.12 KIK69859.1 - 0.00085 19.4 0.3 0.098 12.7 0.0 3.0 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.18 KIK69859.1 - 0.4 10.9 13.9 13 6.1 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper PRKG1_interact PF15898.5 KIK69859.1 - 9.1 7.2 8.0 2.3 9.2 3.1 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KIK69859.1 - 9.8 6.6 12.7 0.51 10.8 1.3 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF4657 PF15552.6 KIK69860.1 - 0.011 15.3 0.3 0.014 14.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Totivirus_coat PF05518.11 KIK69861.1 - 0.67 7.9 1.2 0.59 8.1 1.2 1.0 1 0 0 1 1 1 0 Totivirus coat protein TPR_1 PF00515.28 KIK69862.1 - 3.8e-06 26.5 2.4 0.056 13.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 KIK69862.1 - 3.8e-06 26.7 0.0 6.6e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain TPR_2 PF07719.17 KIK69862.1 - 0.00094 19.1 6.0 0.95 9.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 KIK69862.1 - 0.012 15.8 0.0 0.046 13.9 0.0 2.1 2 0 0 2 2 2 0 DnaJ domain TPR_12 PF13424.6 KIK69862.1 - 2.2 8.7 5.2 6.5 7.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Sad1_UNC PF07738.13 KIK69863.1 - 6e-28 97.5 0.1 1.1e-27 96.7 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal TPR_MLP1_2 PF07926.12 KIK69863.1 - 0.13 12.3 0.3 0.3 11.2 0.3 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tmemb_cc2 PF10267.9 KIK69863.1 - 0.21 10.7 2.4 0.49 9.5 2.4 1.6 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein AAA PF00004.29 KIK69864.1 - 1.5e-38 132.2 0.0 2.5e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK69864.1 - 1.3e-08 34.5 0.0 3.4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KIK69864.1 - 2.3e-07 30.7 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK69864.1 - 1.7e-06 28.5 0.1 0.00012 22.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KIK69864.1 - 3.1e-05 24.0 0.0 6.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK69864.1 - 4.8e-05 23.4 0.3 0.00044 20.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK69864.1 - 6.8e-05 23.0 0.0 0.00023 21.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK69864.1 - 8.7e-05 22.8 0.2 0.0019 18.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KIK69864.1 - 0.00015 21.7 0.1 0.00067 19.6 0.0 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KIK69864.1 - 0.00024 20.6 0.2 0.0016 17.9 0.2 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK69864.1 - 0.00041 20.9 0.0 0.00093 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KIK69864.1 - 0.00041 19.8 0.0 1.3 8.4 0.0 2.7 2 1 1 3 3 3 2 Bacterial TniB protein AAA_33 PF13671.6 KIK69864.1 - 0.00044 20.4 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIK69864.1 - 0.00058 20.1 0.1 0.0024 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIK69864.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK69864.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KIK69864.1 - 0.0032 16.7 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KIK69864.1 - 0.0042 16.7 0.5 0.071 12.7 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KIK69864.1 - 0.0055 16.4 0.1 0.012 15.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KIK69864.1 - 0.0076 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.6 KIK69864.1 - 0.0079 16.6 0.0 0.028 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.6 KIK69864.1 - 0.0088 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 KIK69864.1 - 0.012 15.3 0.1 0.071 12.8 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KIK69864.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KIK69864.1 - 0.016 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KIK69864.1 - 0.02 14.4 0.0 0.058 12.9 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region TsaE PF02367.17 KIK69864.1 - 0.024 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KIK69864.1 - 0.029 14.9 0.1 0.084 13.4 0.1 1.8 2 0 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.17 KIK69864.1 - 0.038 13.1 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KIK69864.1 - 0.043 13.0 0.0 0.089 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KIK69864.1 - 0.043 13.7 0.0 0.16 11.9 0.0 1.8 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 KIK69864.1 - 0.051 13.4 0.1 3.6 7.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Hydin_ADK PF17213.3 KIK69864.1 - 0.063 13.5 0.1 0.4 10.9 0.1 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ATPase PF06745.13 KIK69864.1 - 0.07 12.5 0.0 0.86 8.9 0.0 2.4 2 1 1 3 3 3 0 KaiC AAA_3 PF07726.11 KIK69864.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KIK69864.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein KAP_NTPase PF07693.14 KIK69864.1 - 0.17 11.1 0.2 5.4 6.1 0.1 2.3 1 1 0 2 2 2 0 KAP family P-loop domain SKI PF01202.22 KIK69864.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase tRNA_lig_kinase PF08303.11 KIK69864.1 - 0.2 11.8 0.0 0.44 10.6 0.0 1.5 2 0 0 2 2 1 0 tRNA ligase kinase domain RRM_1 PF00076.22 KIK69865.1 - 9.8e-10 38.1 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KIK69865.1 - 0.0001 22.6 0.2 0.00028 21.1 0.2 1.8 1 0 0 1 1 1 1 PWI domain IFT46_B_C PF12317.8 KIK69865.1 - 0.002 17.9 1.7 0.0032 17.2 0.3 2.0 2 1 0 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal Trehalase PF01204.18 KIK69866.1 - 4.1e-111 372.3 2.2 2e-100 337.1 0.0 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 KIK69866.1 - 2.3e-06 26.8 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase COesterase PF00135.28 KIK69867.1 - 4.6e-97 326.0 0.0 2e-95 320.6 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK69867.1 - 0.00046 20.1 0.1 0.0028 17.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK69867.1 - 0.0024 17.4 0.1 0.0043 16.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FMN_dh PF01070.18 KIK69870.1 - 3.1e-106 355.3 0.0 4.1e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KIK69870.1 - 6.8e-06 25.3 0.9 2.7e-05 23.4 0.9 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KIK69870.1 - 0.00018 20.9 0.0 0.038 13.3 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KIK69870.1 - 0.00034 19.9 0.1 0.00056 19.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Nup54_C PF18437.1 KIK69870.1 - 0.009 15.9 0.5 0.018 15.0 0.5 1.4 1 0 0 1 1 1 1 Nup54 C-terminal interacting domain His_biosynth PF00977.21 KIK69870.1 - 0.05 13.0 0.3 4.2 6.7 0.0 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein PsbX PF06596.11 KIK69871.1 - 0.0077 16.2 0.3 0.089 12.8 0.0 2.3 2 0 0 2 2 2 1 Photosystem II reaction centre X protein (PsbX) ETF PF01012.21 KIK69872.1 - 1.2e-42 145.8 0.3 1.7e-42 145.4 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Nipped-B_C PF12830.7 KIK69873.1 - 4.2e-53 180.1 1.2 3e-52 177.3 1.1 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KIK69873.1 - 1e-13 51.3 0.5 5.2e-13 49.0 0.2 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KIK69873.1 - 0.0013 18.8 0.0 1.5 9.3 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 KIK69873.1 - 0.011 15.8 0.1 0.038 14.0 0.1 2.0 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK69873.1 - 0.014 15.8 0.5 0.33 11.4 0.2 3.4 2 1 1 3 3 3 0 HEAT repeats SIL1 PF16782.5 KIK69873.1 - 0.031 13.5 0.0 0.14 11.4 0.0 2.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 HEAT_EZ PF13513.6 KIK69873.1 - 0.083 13.4 0.4 8.8 7.0 0.1 3.6 2 1 0 2 2 2 0 HEAT-like repeat DUF3106 PF11304.8 KIK69873.1 - 5.1 7.6 5.5 2.4 8.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) HIT PF01230.23 KIK69874.1 - 2.1e-23 82.9 0.1 2.7e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK69874.1 - 3.2e-10 40.5 0.1 4.4e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIK69874.1 - 1.7e-05 24.7 0.1 2.5e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SLAC1 PF03595.17 KIK69875.1 - 1.2e-55 189.1 46.2 1.3e-55 188.9 46.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel AKAP2_C PF15304.6 KIK69876.1 - 2.5 7.3 8.3 3.2 7.0 8.3 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus NFACT-R_1 PF05670.13 KIK69877.1 - 1.9e-42 144.3 0.0 3e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DHR10 PF18595.1 KIK69877.1 - 0.009 16.1 1.2 0.014 15.4 1.2 1.3 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain RsgI_N PF12791.7 KIK69877.1 - 0.49 10.3 0.0 0.49 10.3 0.0 2.1 3 0 0 3 3 3 0 Anti-sigma factor N-terminus zf-RING_2 PF13639.6 KIK69878.1 - 3.1e-13 49.8 3.8 5e-13 49.2 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK69878.1 - 4.7e-09 36.0 4.1 7.6e-09 35.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK69878.1 - 5.4e-09 36.2 3.9 9.5e-09 35.4 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIK69878.1 - 7.3e-09 35.2 1.8 1.3e-08 34.4 1.8 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KIK69878.1 - 3e-08 33.4 2.6 4.8e-08 32.7 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK69878.1 - 3.6e-06 26.8 1.6 5.6e-06 26.2 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK69878.1 - 2.4e-05 24.3 0.8 4.6e-05 23.4 0.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK69878.1 - 6.4e-05 22.7 1.8 0.00011 22.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK69878.1 - 0.00033 20.7 2.1 0.00062 19.8 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIK69878.1 - 0.0038 17.0 4.5 0.0064 16.3 4.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KIK69878.1 - 0.011 15.6 2.5 0.019 14.8 2.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIK69878.1 - 0.014 15.0 4.9 0.023 14.3 4.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KIK69878.1 - 0.086 13.2 1.3 0.17 12.2 1.3 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KIK69878.1 - 0.36 10.8 4.8 0.6 10.0 4.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_5 PF17121.5 KIK69878.1 - 0.52 10.2 2.6 0.78 9.7 1.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KIK69878.1 - 0.57 10.4 4.1 1 9.5 4.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KIK69878.1 - 0.61 10.2 2.9 1.2 9.3 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 KIK69878.1 - 1.1 9.5 3.4 2.1 8.6 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MFS_1 PF07690.16 KIK69879.1 - 4.2e-39 134.5 14.6 1e-37 129.9 15.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK69879.1 - 0.015 14.2 27.5 0.17 10.7 27.5 2.8 1 1 0 1 1 1 0 Sugar (and other) transporter VIT1 PF01988.19 KIK69879.1 - 1 9.2 8.2 0.055 13.3 1.0 2.3 2 0 0 2 2 2 0 VIT family DNA_pol_A_exo1 PF01612.20 KIK69880.1 - 2.8e-47 160.7 0.2 5.1e-47 159.8 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KIK69880.1 - 5.6e-21 75.0 0.6 5.6e-21 75.0 0.6 2.7 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 KIK69880.1 - 1.3e-13 50.7 0.7 2.3e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 HRDC domain p450 PF00067.22 KIK69880.1 - 0.095 11.4 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P450 Fungal_trans PF04082.18 KIK69881.1 - 3.1e-07 29.7 0.0 8.6e-07 28.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK69881.1 - 0.0047 17.0 6.4 0.0078 16.3 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.20 KIK69882.1 - 4.2e-08 33.6 0.0 5.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Asp PF00026.23 KIK69883.1 - 7.1e-46 157.1 1.2 8.8e-46 156.8 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK69883.1 - 0.00084 19.6 0.4 0.0079 16.5 0.4 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK69883.1 - 0.0016 19.1 0.3 1.7 9.3 0.1 3.3 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK69883.1 - 0.002 18.7 0.1 0.75 10.4 0.0 3.3 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KIK69883.1 - 0.02 14.6 0.3 1.1 9.0 0.3 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal LRR_8 PF13855.6 KIK69884.1 - 2.8e-22 78.2 26.1 2.2e-05 24.2 0.6 6.4 6 0 0 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KIK69884.1 - 4.8e-21 74.5 35.6 0.00014 22.2 0.8 8.1 7 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIK69884.1 - 2.1e-15 56.6 11.5 0.00015 21.3 0.8 5.5 3 1 3 6 6 6 6 Leucine-rich repeat Homeobox_KN PF05920.11 KIK69885.1 - 2.9e-19 68.7 1.3 6.4e-19 67.6 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KIK69885.1 - 2.2e-05 24.2 0.1 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain DUF4492 PF14899.6 KIK69887.1 - 0.097 12.6 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) FMO-like PF00743.19 KIK69888.1 - 3.6e-12 45.5 0.0 6.8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK69888.1 - 1.7e-10 40.6 0.0 2.7e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK69888.1 - 1.2e-07 31.8 0.0 5.3e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK69888.1 - 5.2e-06 25.9 0.0 0.00099 18.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK69888.1 - 6.9e-05 22.2 0.0 0.00021 20.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK69888.1 - 0.00015 21.8 0.5 0.61 10.1 0.0 3.8 3 1 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIK69888.1 - 0.038 14.1 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_4 PF01565.23 KIK69889.1 - 5.3e-18 65.1 3.3 1.1e-17 64.0 3.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK69889.1 - 3.8e-11 42.9 0.2 8.8e-11 41.7 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like RabGAP-TBC PF00566.18 KIK69890.1 - 8.1e-28 97.5 0.0 1.3e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 KIK69890.1 - 0.00034 20.2 0.0 0.00081 19.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Aminotran_1_2 PF00155.21 KIK69891.1 - 8.1e-10 38.4 0.0 1.9e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3292 PF11696.8 KIK69892.1 - 1.2e-202 674.8 0.0 1.5e-202 674.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) zf-C3HC4 PF00097.25 KIK69894.1 - 0.016 15.1 8.5 0.024 14.5 8.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK69894.1 - 0.046 13.6 9.0 0.064 13.1 9.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK69894.1 - 0.12 12.2 9.1 0.2 11.5 9.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK69894.1 - 0.23 11.6 6.2 1.2 9.2 6.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SCA7 PF08313.12 KIK69894.1 - 1.3 9.0 5.0 2.7 8.0 5.0 1.5 1 1 0 1 1 1 0 SCA7, zinc-binding domain Glyco_hydro_71 PF03659.14 KIK69895.1 - 1.8e-117 392.4 15.1 2e-117 392.2 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fungal_trans PF04082.18 KIK69896.1 - 1.1e-24 86.9 0.2 1.8e-24 86.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK69896.1 - 6.2e-05 23.0 9.5 0.00012 22.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GH131_N PF18271.1 KIK69897.1 - 1.7e-86 290.1 0.0 1.9e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 KIK69897.1 - 0.00078 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase Laminin_G_2 PF02210.24 KIK69897.1 - 0.061 13.9 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 Laminin G domain Glyco_transf_15 PF01793.16 KIK69898.1 - 3.3e-122 407.8 9.1 3.9e-122 407.6 9.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3045 PF11243.8 KIK69898.1 - 0.053 13.7 0.0 4.5 7.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3045) EGF_3 PF12947.7 KIK69898.1 - 0.15 12.2 1.6 0.27 11.5 1.6 1.4 1 0 0 1 1 1 0 EGF domain Methyltransf_15 PF09445.10 KIK69900.1 - 7.7e-36 123.1 0.0 1.5e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KIK69900.1 - 4.1e-07 30.6 0.0 7.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK69900.1 - 2e-05 24.4 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIK69900.1 - 5e-05 23.1 0.0 8.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KIK69900.1 - 8.6e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KIK69900.1 - 0.00036 21.1 0.0 0.00063 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK69900.1 - 0.0052 16.2 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KIK69900.1 - 0.0089 15.7 0.1 0.084 12.6 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KIK69900.1 - 0.012 15.6 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KIK69900.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase N6_Mtase PF02384.16 KIK69900.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase SAM_MT PF04445.13 KIK69900.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TERB2 PF15101.6 KIK69900.1 - 0.21 11.6 0.9 0.31 11.1 0.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Clathrin PF00637.20 KIK69901.1 - 2e-25 89.3 0.3 2.4e-24 85.8 0.0 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KIK69901.1 - 0.00012 22.3 0.0 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK69901.1 - 0.0026 18.6 1.5 0.04 14.8 0.1 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Vps39_2 PF10367.9 KIK69901.1 - 0.0092 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KIK69901.1 - 0.027 14.1 0.2 0.057 13.0 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CENP-B_dimeris PF09026.10 KIK69901.1 - 0.062 13.7 16.0 0.15 12.5 16.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3H2C3 PF17122.5 KIK69901.1 - 0.2 11.7 1.6 0.46 10.6 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger Sigma70_ner PF04546.13 KIK69901.1 - 0.29 11.0 5.5 0.58 10.0 5.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-RING_2 PF13639.6 KIK69901.1 - 0.31 11.4 3.3 0.87 10.0 1.2 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KIK69901.1 - 1.2 9.2 3.7 3.5 7.7 3.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Cwf_Cwc_15 PF04889.12 KIK69901.1 - 3.8 7.2 16.9 7.2 6.3 16.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Acetyltransf_1 PF00583.25 KIK69903.1 - 1.1e-12 48.2 0.0 1.5e-12 47.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK69903.1 - 3.5e-10 40.2 0.0 4.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK69903.1 - 1.1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK69903.1 - 2e-07 31.0 0.0 1.8e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK69903.1 - 9.2e-06 26.4 0.0 1.2e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK69903.1 - 5.2e-05 23.0 0.0 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK69903.1 - 0.00028 20.8 0.6 0.00058 19.8 0.2 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KIK69903.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KIK69903.1 - 0.0084 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KIK69903.1 - 0.019 15.0 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK69903.1 - 0.061 13.5 0.0 0.079 13.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIK69903.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_1 PF00583.25 KIK69904.1 - 1.4e-14 54.3 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK69904.1 - 8.2e-11 42.2 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK69904.1 - 6.5e-09 35.8 0.0 4.9e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK69904.1 - 2.1e-06 28.5 0.0 2.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK69904.1 - 2.4e-06 27.4 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIK69904.1 - 1.3e-05 25.0 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK69904.1 - 5.8e-05 23.0 0.2 0.00039 20.4 0.1 2.1 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KIK69904.1 - 0.00034 20.7 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KIK69904.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KIK69904.1 - 0.0038 17.0 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KIK69904.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIK69904.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KIK69904.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_15 PF17013.5 KIK69904.1 - 0.19 11.1 0.0 0.38 10.2 0.0 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Amidohydro_1 PF01979.20 KIK69905.1 - 3.9e-13 49.4 0.1 3.1e-09 36.6 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.11 KIK69905.1 - 3.7e-12 46.5 2.8 2.1e-06 27.5 0.2 3.3 4 1 0 4 4 4 2 Amidohydrolase family tRNA-synt_2 PF00152.20 KIK69907.1 - 1.6e-75 254.1 0.0 2.1e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK69907.1 - 8.5e-13 48.1 0.1 2.9e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIK69907.1 - 6.2e-09 35.7 0.1 0.00011 21.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) MFS_1 PF07690.16 KIK69909.1 - 1.2e-21 77.0 49.0 4.8e-17 61.9 28.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KIK69910.1 - 4.2e-47 158.0 11.9 1.7e-18 66.3 0.1 5.0 3 2 2 5 5 5 5 Mitochondrial carrier protein Serine_protease PF18405.1 KIK69910.1 - 0.012 14.8 1.3 0.071 12.3 0.2 2.3 2 1 0 3 3 3 0 Gammaproteobacterial serine protease SNF2_N PF00176.23 KIK69911.1 - 3.2e-61 207.0 0.0 9.8e-60 202.1 0.0 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK69911.1 - 7.3e-17 61.7 0.0 1.9e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK69911.1 - 1.1e-09 38.5 0.0 2.2e-07 31.0 0.0 3.9 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK69911.1 - 0.0014 17.8 0.0 0.0052 16.0 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KIK69911.1 - 0.0024 17.6 0.1 0.17 11.5 0.0 2.7 3 0 0 3 3 3 1 SWI2/SNF2 ATPase Kazal_3 PF18434.1 KIK69911.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain FXMRP1_C_core PF12235.8 KIK69911.1 - 0.33 11.6 9.1 0.74 10.5 1.6 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal TFIIE-A_C PF11521.8 KIK69911.1 - 1.6 9.0 5.5 2 8.8 0.7 3.1 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Cwf_Cwc_15 PF04889.12 KIK69911.1 - 8.3 6.1 12.0 0.39 10.4 1.0 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CoA_transf_3 PF02515.17 KIK69912.1 - 1.3e-44 152.9 0.7 2.8e-36 125.4 0.0 2.3 2 1 0 2 2 2 2 CoA-transferase family III Ribosomal_L23eN PF03939.13 KIK69914.1 - 2e-24 85.5 9.7 2e-24 85.5 9.7 2.4 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KIK69914.1 - 1.7e-15 57.1 3.5 1.7e-15 57.1 3.5 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 KIK69914.1 - 0.012 15.9 0.3 0.016 15.5 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5451) HisG PF01634.18 KIK69915.1 - 2.8e-54 183.4 0.1 4.6e-54 182.7 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KIK69915.1 - 1.5e-28 98.7 0.0 6.2e-28 96.8 0.0 2.0 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 KIK69915.1 - 0.00052 20.0 0.0 0.00072 19.6 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like MAD PF05557.13 KIK69916.1 - 1.3e-34 119.6 58.4 3e-33 115.1 15.5 2.8 2 1 0 2 2 2 2 Mitotic checkpoint protein DUF2163 PF09931.9 KIK69916.1 - 0.98 9.6 4.7 0.56 10.4 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) zf-C2H2 PF00096.26 KIK69919.1 - 4.4e-07 30.0 13.1 3.6e-05 24.0 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK69919.1 - 8.5e-07 29.3 10.0 0.0015 19.2 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK69919.1 - 7.1e-05 23.1 8.3 0.044 14.2 1.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf_ZIC PF18366.1 KIK69919.1 - 0.024 14.7 0.9 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 KIK69919.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KIK69919.1 - 0.076 13.3 4.3 0.21 11.9 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIK69919.1 - 0.2 12.0 3.8 0.56 10.6 3.8 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIK69919.1 - 1.1 9.4 8.8 3 8.0 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger O-FucT PF10250.9 KIK69922.1 - 8.8e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Prenyltrans PF00432.21 KIK69924.1 - 3.7e-25 87.3 10.8 7.3e-07 28.8 0.3 5.1 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat NOT2_3_5 PF04153.18 KIK69926.1 - 1.5e-31 109.2 0.3 1.5e-31 109.2 0.3 2.3 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Glyco_hydro_20 PF00728.22 KIK69927.1 - 8.8e-92 308.2 0.0 1.1e-91 307.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIK69927.1 - 6.9e-15 55.9 0.0 1.3e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIK69927.1 - 1.6e-06 28.9 0.1 1.5e-05 25.8 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyoxalase_4 PF13669.6 KIK69927.1 - 0.023 15.0 0.0 5.2 7.4 0.0 3.1 3 1 1 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ENTH PF01417.20 KIK69928.1 - 2.4e-45 153.6 0.1 4.2e-45 152.8 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KIK69928.1 - 0.0043 16.1 0.1 0.0094 15.0 0.0 1.6 2 0 0 2 2 2 1 ANTH domain Epimerase PF01370.21 KIK69929.1 - 5.7e-20 71.8 0.0 7.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK69929.1 - 1.2e-13 51.3 0.0 2.5e-13 50.3 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK69929.1 - 1.3e-13 50.6 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK69929.1 - 1.6e-07 30.7 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK69929.1 - 6.6e-07 29.0 0.0 9.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK69929.1 - 4.7e-05 22.7 0.1 9.3e-05 21.7 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK69929.1 - 8.5e-05 22.2 0.7 0.00016 21.3 0.5 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KIK69929.1 - 0.0006 19.3 0.2 0.0041 16.6 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 KIK69929.1 - 0.1 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KIK69929.1 - 0.27 11.1 0.8 1.1 9.2 0.8 2.1 1 1 0 1 1 1 0 KR domain Tetraspanin PF00335.20 KIK69930.1 - 3.3e-10 40.1 4.7 4.6e-10 39.6 4.7 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3037 PF11236.8 KIK69930.1 - 0.21 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) SLC3A2_N PF16028.5 KIK69931.1 - 0.0023 17.4 0.3 0.0029 17.1 0.3 1.1 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus DUF5326 PF17260.2 KIK69931.1 - 0.0052 16.9 0.2 0.0065 16.6 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5326) Ca_hom_mod PF14798.6 KIK69931.1 - 0.0081 15.3 0.1 0.0092 15.1 0.1 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator OppC_N PF12911.7 KIK69931.1 - 0.014 15.4 0.6 0.02 14.9 0.6 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FeoB_associated PF12669.7 KIK69931.1 - 0.35 11.3 1.2 0.53 10.7 1.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Phage_Gp23 PF10669.9 KIK69932.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF202 PF02656.15 KIK69933.1 - 7.2 7.1 6.6 16 6.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PEP_mutase PF13714.6 KIK69934.1 - 4.5e-61 206.3 0.2 5.1e-61 206.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Radical_SAM PF04055.21 KIK69934.1 - 0.0045 17.4 0.1 0.014 15.8 0.0 1.9 1 1 0 2 2 2 1 Radical SAM superfamily AP_endonuc_2 PF01261.24 KIK69934.1 - 0.0051 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 KIK69935.1 - 6.1e-37 127.4 34.9 6.1e-37 127.4 34.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK69935.1 - 1.9e-08 33.6 12.3 1.9e-08 33.6 12.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3464 PF11947.8 KIK69935.1 - 0.016 15.0 3.0 0.031 14.0 0.2 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 zf-RING_2 PF13639.6 KIK69937.1 - 9.3e-11 41.9 3.5 2.7e-10 40.4 2.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIK69937.1 - 5.9e-09 36.1 8.4 9.9e-08 32.2 2.1 2.4 2 1 1 3 3 3 2 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIK69937.1 - 9.4e-08 31.8 2.0 9.4e-08 31.8 2.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK69937.1 - 1.4e-07 31.1 1.5 2.4e-07 30.3 1.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KIK69937.1 - 3.5e-07 30.0 1.5 3.5e-07 30.0 1.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK69937.1 - 6.3e-07 29.3 2.4 6.3e-07 29.3 2.4 1.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK69937.1 - 8.6e-06 25.7 3.8 1.1e-05 25.3 2.5 1.7 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 KIK69937.1 - 0.00011 22.3 2.7 0.00027 21.0 2.7 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KIK69937.1 - 0.00015 21.8 2.6 0.0057 16.7 2.6 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK69937.1 - 0.00022 20.8 1.1 0.00032 20.3 1.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KIK69937.1 - 0.0033 17.5 1.0 0.0065 16.6 1.0 1.6 1 1 0 1 1 1 1 RING-variant domain PHD PF00628.29 KIK69937.1 - 0.0036 17.2 2.2 0.0055 16.6 2.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.6 KIK69937.1 - 0.0053 16.6 1.3 0.0053 16.6 1.3 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK69937.1 - 0.021 14.7 4.3 0.021 14.7 2.8 1.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KIK69937.1 - 0.035 14.0 0.6 0.058 13.3 0.2 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 APH PF01636.23 KIK69939.1 - 4e-07 30.2 0.1 7.1e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK69939.1 - 0.0067 16.0 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIK69939.1 - 0.037 13.3 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 KIK69939.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 KIK69940.1 - 7.3e-10 39.2 0.0 1.1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF676 PF05057.14 KIK69941.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KIK69941.1 - 0.0028 17.5 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KIK69941.1 - 0.048 14.3 0.2 0.089 13.4 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family HTH_31 PF13560.6 KIK69941.1 - 0.05 14.0 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 KIK69941.1 - 0.051 13.2 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK69941.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein PAM2 PF07145.15 KIK69942.1 - 0.0067 16.0 0.8 0.0067 16.0 0.8 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region O-FucT PF10250.9 KIK69943.1 - 3.1e-07 30.4 0.0 5.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aconitase PF00330.20 KIK69945.1 - 7.8e-153 509.8 0.0 9.2e-153 509.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK69945.1 - 1.3e-31 109.6 0.0 2.1e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain ATP-synt_C PF00137.21 KIK69946.1 - 1.1e-34 118.5 34.9 4.5e-22 78.1 16.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C NUDIX_4 PF14815.6 KIK69947.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain Cu-oxidase_2 PF07731.14 KIK69948.1 - 1.3e-37 128.6 3.2 3.6e-35 120.7 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KIK69948.1 - 5.1e-36 124.2 0.0 1e-34 119.9 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK69948.1 - 6.5e-33 113.3 3.9 1.5e-32 112.1 0.0 3.1 4 1 0 4 4 4 1 Multicopper oxidase DUF2569 PF10754.9 KIK69949.1 - 0.017 15.6 10.3 0.017 15.6 10.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2157 PF09925.9 KIK69949.1 - 4.9 6.9 7.9 5.3 6.8 3.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) ELFV_dehydrog PF00208.21 KIK69950.1 - 5e-55 186.9 0.0 7.2e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KIK69950.1 - 1.4e-19 69.3 0.0 3.4e-14 51.4 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase adh_short PF00106.25 KIK69951.1 - 4e-46 157.0 1.7 4.8e-46 156.7 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK69951.1 - 1.1e-31 110.2 0.3 1.4e-31 109.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK69951.1 - 0.00067 19.6 0.4 0.0011 18.9 0.4 1.2 1 0 0 1 1 1 1 KR domain SAM_2 PF07647.17 KIK69952.1 - 2.2e-09 37.3 0.1 5.2e-08 32.9 0.0 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIK69952.1 - 0.0002 21.7 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 KIK69952.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4508 PF14969.6 KIK69952.1 - 0.072 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) IGR PF09597.10 KIK69952.1 - 0.087 12.9 0.3 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 IGR protein motif Peptidase_M54 PF07998.11 KIK69953.1 - 2.2e-06 27.8 0.1 5.2e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_3 PF13582.6 KIK69953.1 - 0.059 13.9 0.2 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KIK69953.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KIK69953.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KIK69953.1 - 0.097 12.5 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.8 KIK69953.1 - 0.18 11.4 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 KIK69953.1 - 0.25 9.9 0.5 0.46 9.0 0.5 1.3 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 KIK69953.1 - 0.54 10.4 2.3 0.97 9.5 2.2 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 EHN PF06441.12 KIK69954.1 - 2e-35 121.4 0.2 1.7e-34 118.4 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK69954.1 - 2.2e-14 53.7 0.1 3.2e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK69954.1 - 5.4e-05 23.9 2.4 0.00011 22.9 2.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_76 PF03663.14 KIK69955.1 - 1.2e-31 110.6 16.4 1.1e-24 87.7 2.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 DUF4595 PF15283.6 KIK69955.1 - 0.024 14.7 0.1 0.036 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold Dynamin_N PF00350.23 KIK69957.1 - 2.9e-19 69.7 0.7 9.7e-19 68.0 0.1 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KIK69957.1 - 1.9e-13 50.5 0.3 2.7e-12 46.8 0.0 3.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK69957.1 - 2.6e-07 30.4 0.2 1.6e-06 27.8 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK69957.1 - 0.00058 19.8 2.0 0.45 10.4 0.3 3.0 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KIK69957.1 - 0.0088 15.7 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KIK69957.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Septin Roc PF08477.13 KIK69957.1 - 0.013 15.7 0.0 0.89 9.8 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KIK69957.1 - 0.014 14.4 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 KIK69957.1 - 0.026 14.5 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KIK69957.1 - 0.034 13.9 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain adh_short_C2 PF13561.6 KIK69958.1 - 2.9e-36 125.2 0.0 6.8e-20 71.6 0.0 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK69958.1 - 8.8e-33 113.4 0.2 1e-20 74.1 0.0 3.4 3 1 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 KIK69958.1 - 1e-07 32.0 0.7 2e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KIK69958.1 - 0.00053 19.4 0.1 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KIK69958.1 - 0.0036 16.8 0.1 0.0052 16.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK69958.1 - 0.0047 16.4 0.2 0.0072 15.8 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIK69958.1 - 0.012 16.2 0.2 0.022 15.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SKI PF01202.22 KIK69958.1 - 0.039 14.1 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase TrkA_N PF02254.18 KIK69958.1 - 0.075 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 KIK69958.1 - 0.13 11.3 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DIOX_N PF14226.6 KIK69959.1 - 1.5e-25 90.2 0.0 2.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK69959.1 - 1.7e-15 57.3 0.0 3.7e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KIK69960.1 - 9.4e-70 235.0 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69960.1 - 3.2e-40 138.1 0.0 4.1e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK69960.1 - 2.7e-06 26.9 0.0 9.8e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIK69960.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK69960.1 - 0.01 15.7 0.1 1 9.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KIK69960.1 - 0.064 12.9 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pyr_redox_2 PF07992.14 KIK69961.1 - 7.4e-53 179.7 0.1 8.5e-53 179.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK69961.1 - 2.1e-18 66.7 0.5 3.4e-15 56.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK69961.1 - 2.2e-18 66.6 0.3 1.6e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK69961.1 - 4.6e-06 26.0 0.1 5.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK69961.1 - 2.5e-05 24.1 0.1 0.0028 17.3 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK69961.1 - 3.5e-05 24.0 0.1 0.0037 17.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK69961.1 - 4e-05 22.9 2.8 0.0049 16.0 0.1 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK69961.1 - 0.00013 21.4 0.0 0.0054 16.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK69961.1 - 0.00014 21.1 1.6 0.0028 16.8 0.2 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KIK69961.1 - 0.00037 20.9 0.1 0.085 13.3 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIK69961.1 - 0.0014 18.7 0.3 2.7 8.0 0.0 3.4 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KIK69961.1 - 0.0017 17.7 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KIK69961.1 - 0.0021 17.0 0.8 0.062 12.1 0.2 2.6 1 1 2 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KIK69961.1 - 0.0028 16.4 1.3 0.044 12.5 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 KIK69961.1 - 0.0033 16.6 0.1 0.14 11.3 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 KIK69961.1 - 0.012 16.2 0.0 0.64 10.6 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIK69961.1 - 0.013 15.2 0.6 3.9 7.1 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KIK69961.1 - 0.17 11.9 0.3 23 4.9 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Per1 PF04080.13 KIK69963.1 - 2.6e-100 335.4 13.2 3.2e-100 335.1 13.2 1.1 1 0 0 1 1 1 1 Per1-like family Hist_deacetyl PF00850.19 KIK69964.1 - 1.2e-78 264.7 0.0 1.5e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_20 PF00728.22 KIK69965.1 - 1.2e-84 284.7 0.0 1.5e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIK69965.1 - 3.9e-11 43.8 0.0 1.1e-10 42.3 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIK69965.1 - 0.0015 19.3 0.0 0.0072 17.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 MFS_1 PF07690.16 KIK69966.1 - 2.1e-20 73.0 54.2 1.9e-10 40.2 20.6 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KIK69967.1 - 1.9e-65 221.5 0.0 2.5e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 KIK69967.1 - 0.023 14.9 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Stirrup TFR_dimer PF04253.15 KIK69969.1 - 2.7e-20 72.7 0.0 3.5e-19 69.1 0.0 2.5 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIK69969.1 - 6.3e-16 58.7 0.0 1.1e-13 51.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M28 PA PF02225.22 KIK69969.1 - 7.2e-09 35.6 0.2 1.9e-08 34.2 0.1 1.7 2 0 0 2 2 2 1 PA domain Dynamin_M PF01031.20 KIK69970.1 - 1.8e-31 109.4 0.3 7.5e-31 107.4 0.3 1.8 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK69970.1 - 2.6e-27 95.9 0.0 5.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK69970.1 - 5.5e-10 39.3 0.1 1.9e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK69970.1 - 1.5e-05 25.1 0.0 0.00014 21.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK69970.1 - 0.00025 21.5 0.2 0.35 11.2 0.0 3.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 KIK69970.1 - 0.0067 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK69970.1 - 0.062 13.8 0.0 0.22 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KIK69970.1 - 0.12 12.2 1.6 0.42 10.4 0.0 2.4 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK69970.1 - 5.5 7.4 6.4 5.3 7.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain FMO-like PF00743.19 KIK69971.1 - 6.7e-12 44.6 0.0 8.4e-11 41.0 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK69971.1 - 1.6e-10 41.0 0.0 1.7e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIK69971.1 - 8.7e-08 31.7 0.0 0.00016 20.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK69971.1 - 1.4e-07 31.1 0.0 3.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK69971.1 - 4.2e-07 29.5 0.0 8.9e-06 25.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK69971.1 - 9.1e-06 25.5 0.0 0.0069 16.0 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK69971.1 - 0.00017 21.6 0.2 0.0072 16.3 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK69971.1 - 0.00028 21.4 0.1 0.066 13.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK69971.1 - 0.003 16.7 0.0 0.011 14.8 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.20 KIK69971.1 - 0.011 15.8 0.0 0.25 11.4 0.0 2.4 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIK69971.1 - 0.013 14.6 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KIK69971.1 - 0.027 13.8 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KIK69971.1 - 0.033 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FIST PF08495.10 KIK69972.1 - 1.6e-06 28.3 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 FIST N domain efThoc1 PF11957.8 KIK69973.1 - 2.3e-65 221.2 7.6 7.4e-56 189.8 0.2 2.7 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Borrelia_P83 PF05262.11 KIK69973.1 - 0.0016 17.1 2.1 0.0016 17.1 2.1 2.1 3 0 0 3 3 3 1 Borrelia P83/100 protein Peptidase_S9 PF00326.21 KIK69974.1 - 1.4e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK69974.1 - 2.7e-06 26.8 0.2 2.8e-05 23.5 0.0 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK69974.1 - 4.8e-06 27.3 1.5 8e-06 26.6 1.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK69974.1 - 0.036 13.6 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF1749 PF08538.10 KIK69974.1 - 0.097 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) ADH_zinc_N PF00107.26 KIK69975.1 - 7e-27 94.0 0.1 1.3e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK69975.1 - 3.2e-15 57.3 0.0 5.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK69975.1 - 7.4e-10 38.7 0.0 3.3e-08 33.4 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 KIK69975.1 - 0.047 13.8 0.0 6 7.0 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NifU PF01106.17 KIK69976.1 - 0.049 13.8 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 NifU-like domain Sigma54_CBD PF04963.13 KIK69976.1 - 0.079 12.8 0.0 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain Phytase PF02333.15 KIK69976.1 - 0.17 10.8 0.0 8 5.3 0.0 2.2 2 0 0 2 2 2 0 Phytase Phage_Coat_B PF05356.11 KIK69977.1 - 1.5 8.8 4.8 1.3 9.0 0.6 2.7 2 1 0 2 2 2 0 Phage Coat protein B Glyco_hydro_16 PF00722.21 KIK69978.1 - 0.0003 20.3 0.1 0.00053 19.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NAD_binding_8 PF13450.6 KIK69979.1 - 9.1e-12 45.0 0.0 3.2e-10 40.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK69979.1 - 1.6e-09 37.5 0.0 1.6e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK69979.1 - 1.8e-09 36.6 0.1 1.4e-08 33.6 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK69979.1 - 2.9e-09 36.6 0.0 1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK69979.1 - 3.2e-07 29.8 0.0 3.6e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK69979.1 - 2.6e-05 24.3 1.2 0.0056 16.7 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KIK69979.1 - 7.7e-05 22.4 0.2 0.0018 17.9 0.2 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK69979.1 - 0.00012 22.6 0.1 0.025 15.1 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK69979.1 - 0.029 14.4 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KIK69979.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KIK69979.1 - 0.15 11.1 0.0 2.8 6.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L1 PF00687.21 KIK69980.1 - 3.5e-50 170.6 0.1 3.5e-50 170.6 0.1 2.8 3 1 0 3 3 3 1 Ribosomal protein L1p/L10e family ADH_N PF08240.12 KIK69981.1 - 2.3e-29 101.4 2.1 4.3e-29 100.6 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK69981.1 - 6.2e-20 71.5 0.0 9.7e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK69981.1 - 1.8e-05 24.2 0.2 3.2e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KIK69981.1 - 1.9e-05 25.7 0.0 2.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIK69981.1 - 0.00026 20.3 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KIK69981.1 - 0.0043 17.2 0.1 0.0092 16.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIK69981.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4121 PF13497.6 KIK69981.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Peptidase_M64 PF09471.10 KIK69982.1 - 1.2e-27 97.1 0.0 5.6e-27 94.9 0.0 1.8 1 1 0 1 1 1 1 IgA Peptidase M64 Sulfolobus_pRN PF05584.11 KIK69982.1 - 0.045 13.8 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein AtuA PF07287.11 KIK69983.1 - 1.3e-117 392.5 0.0 1.5e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FMO-like PF00743.19 KIK69984.1 - 7e-15 54.4 0.0 3.9e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK69984.1 - 1.3e-12 47.8 0.0 2.7e-10 40.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK69984.1 - 1.2e-11 44.4 0.0 8.8e-09 35.0 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK69984.1 - 3.1e-11 43.1 0.0 1.2e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK69984.1 - 9.2e-10 38.2 0.0 5.8e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIK69984.1 - 5.6e-08 32.9 1.4 0.00073 19.6 0.1 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KIK69984.1 - 8.5e-06 25.6 0.2 0.0079 15.8 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK69984.1 - 1.5e-05 25.4 0.1 0.0062 17.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK69984.1 - 0.013 15.6 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KIK69984.1 - 0.014 14.4 0.0 0.04 13.0 0.0 1.7 2 1 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIK69984.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KIK69984.1 - 0.13 11.4 0.0 0.83 8.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain zf-MYND PF01753.18 KIK69986.1 - 1.1e-07 31.8 5.1 1.7e-07 31.2 5.1 1.3 1 0 0 1 1 1 1 MYND finger DUF3772 PF12607.8 KIK69986.1 - 0.049 13.4 0.5 11 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Pkinase PF00069.25 KIK69987.1 - 1.9e-72 243.8 0.0 3.3e-72 243.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK69987.1 - 3.4e-51 174.0 0.0 5.4e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK69987.1 - 6.4e-05 21.9 3.2 7.1e-05 21.8 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KIK69987.1 - 0.0037 16.6 0.0 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RICTOR_N PF14664.6 KIK69987.1 - 0.017 14.1 4.9 1.4 7.8 1.1 3.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term DUF4704 PF15787.5 KIK69987.1 - 0.069 12.4 1.1 2.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) SCAB-ABD PF16711.5 KIK69987.1 - 0.12 12.3 0.3 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein Haspin_kinase PF12330.8 KIK69987.1 - 0.16 10.9 0.1 3.8 6.4 0.0 2.8 2 1 0 2 2 2 0 Haspin like kinase domain IFRD PF05004.13 KIK69988.1 - 0.046 12.8 0.1 0.063 12.4 0.1 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Anoctamin PF04547.12 KIK69989.1 - 3.4e-85 286.6 3.5 4.3e-85 286.2 3.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_trans_CmpB PF06541.11 KIK69989.1 - 2.4 8.4 8.1 0.41 10.9 2.2 2.5 2 1 0 2 2 2 0 Putative ABC-transporter type IV Glyco_hydro_61 PF03443.14 KIK69990.1 - 4.5e-55 186.8 0.0 5.1e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UQ_con PF00179.26 KIK69992.1 - 1e-42 145.1 0.0 1.3e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KIK69992.1 - 2e-19 69.1 1.5 2.6e-19 68.7 0.1 1.8 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KIK69992.1 - 0.0027 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_6 PF18039.1 KIK69992.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Acetyltransf_10 PF13673.7 KIK69993.1 - 6.1e-08 32.7 0.0 7.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK69993.1 - 8.7e-07 29.2 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK69993.1 - 0.00011 22.6 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK69993.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase ArfGap PF01412.18 KIK69994.1 - 1.3e-33 115.5 0.4 1.3e-33 115.5 0.4 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf MEIOC PF15189.6 KIK69994.1 - 0.0089 15.7 0.5 0.018 14.7 0.5 1.4 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC F-box-like PF12937.7 KIK69995.1 - 0.00083 19.2 0.1 0.0018 18.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nop14 PF04147.12 KIK69995.1 - 4.4 5.4 8.1 6.1 4.9 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family Clat_adaptor_s PF01217.20 KIK69996.1 - 2.1e-56 189.8 3.4 2.3e-56 189.7 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KIK69996.1 - 0.046 13.3 0.1 0.057 13.0 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Annexin PF00191.20 KIK69997.1 - 2.2e-59 197.4 7.4 3.5e-15 55.8 0.1 4.3 4 0 0 4 4 4 4 Annexin CsbD PF05532.12 KIK69998.1 - 1.1e-18 66.8 12.5 1.4e-10 40.9 4.2 2.0 1 1 1 2 2 2 2 CsbD-like FtsJ PF01728.19 KIK69999.1 - 1e-07 32.2 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Glyco_hydro_76 PF03663.14 KIK70000.1 - 2.9e-24 86.3 4.8 1.7e-21 77.2 0.7 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 NUP PF06516.11 KIK70001.1 - 1.6e-119 398.8 0.0 1.9e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) TauD PF02668.16 KIK70002.1 - 1.8e-36 126.3 0.0 2.6e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Xan_ur_permease PF00860.20 KIK70003.1 - 6.2e-62 209.5 32.0 1.2e-60 205.3 32.0 2.1 1 1 0 1 1 1 1 Permease family 4HBT_2 PF13279.6 KIK70004.1 - 3.4e-09 37.2 0.0 5.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Trp_halogenase PF04820.14 KIK70006.1 - 1.5e-10 40.5 0.0 1.9e-07 30.3 0.0 3.0 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KIK70006.1 - 0.00016 21.8 0.1 0.002 18.3 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK70006.1 - 0.0058 16.3 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK70006.1 - 0.021 14.8 0.1 0.078 13.0 0.0 1.9 1 1 1 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KIK70006.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein zf-CRD PF17979.1 KIK70006.1 - 0.34 11.0 2.9 0.68 10.0 2.9 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions EB1 PF03271.17 KIK70007.1 - 4.1e-17 62.1 2.1 4.8e-17 61.9 0.7 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KIK70007.1 - 8.9e-07 29.1 0.2 1.4e-06 28.5 0.2 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KIK70007.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like MFS_1 PF07690.16 KIK70008.1 - 1.6e-27 96.4 58.4 3.1e-21 75.7 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK70008.1 - 9.5e-05 21.4 36.8 0.00064 18.7 7.3 3.6 1 1 1 3 3 3 2 Sugar (and other) transporter DUF3789 PF12664.7 KIK70008.1 - 0.47 10.2 0.0 0.47 10.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3789) DUF3613 PF12266.8 KIK70009.1 - 0.094 12.5 0.3 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Peptidase_S10 PF00450.22 KIK70010.1 - 2.1e-91 307.5 2.1 2.6e-91 307.1 2.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Proteasome PF00227.26 KIK70012.1 - 1.9e-33 115.6 0.0 2.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.9 KIK70013.1 - 9e-51 172.4 0.2 1.1e-50 172.1 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Pkinase PF00069.25 KIK70014.1 - 6.1e-43 147.1 0.0 8.1e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70014.1 - 1.4e-28 99.9 0.0 8e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK70014.1 - 0.00012 21.5 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIK70014.1 - 0.0015 18.5 0.1 0.004 17.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK70014.1 - 0.0017 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK70014.1 - 0.0037 16.1 0.0 0.0048 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK70014.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIK70014.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4912 PF16258.5 KIK70015.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) VIR_N PF15912.5 KIK70016.1 - 0.0054 16.4 2.2 0.0065 16.1 2.2 1.0 1 0 0 1 1 1 1 Virilizer, N-terminal Flagellin_N PF00669.20 KIK70016.1 - 0.019 15.1 1.2 0.025 14.7 1.2 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region RAP1 PF07218.11 KIK70016.1 - 0.045 12.0 0.2 0.052 11.8 0.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Rax2 PF12768.7 KIK70017.1 - 3.9e-05 23.2 0.1 6.1e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Herpes_gE PF02480.16 KIK70017.1 - 0.0029 16.4 0.2 0.0043 15.9 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 KIK70017.1 - 0.0032 17.4 0.2 0.0062 16.4 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family Trp_oprn_chp PF09534.10 KIK70017.1 - 0.0039 17.0 0.7 0.0088 15.9 0.7 1.6 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 KIK70017.1 - 0.0045 17.8 0.0 0.011 16.6 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KIK70017.1 - 0.007 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Protocadherin Stevor PF17410.2 KIK70017.1 - 0.034 13.7 0.7 0.05 13.2 0.7 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RCR PF12273.8 KIK70017.1 - 0.56 10.9 6.3 2.5 8.8 6.3 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MGC-24 PF05283.11 KIK70017.1 - 2.1 8.8 9.7 0.63 10.5 5.9 2.1 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Fungal_trans PF04082.18 KIK70018.1 - 6e-20 71.4 0.2 1.8e-19 69.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK70018.1 - 1.3e-07 31.6 10.1 2.3e-07 30.8 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KIK70019.1 - 2.7e-07 30.3 0.2 4.2e-05 23.1 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK70019.1 - 8.2e-05 22.3 0.0 0.0039 16.8 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3842 PF12953.7 KIK70019.1 - 0.0027 18.1 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) Sacchrp_dh_NADP PF03435.18 KIK70019.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIK70019.1 - 0.016 15.2 0.1 0.12 12.2 0.0 2.2 2 1 0 2 2 2 0 KR domain SapB_2 PF03489.17 KIK70019.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 2 Sugar_tr PF00083.24 KIK70020.1 - 2e-108 363.2 19.4 2.4e-108 362.9 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK70020.1 - 2.5e-20 72.7 30.3 2.5e-20 72.7 30.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TPR_19 PF14559.6 KIK70020.1 - 0.08 13.5 0.5 0.15 12.6 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KIK70021.1 - 5.3e-19 68.3 0.0 2.7e-16 59.4 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1233 PF06806.12 KIK70021.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative excisionase (DUF1233) AA_permease_2 PF13520.6 KIK70021.1 - 0.13 11.0 1.0 0.26 10.1 0.3 1.7 2 0 0 2 2 2 0 Amino acid permease Glyco_hydro_88 PF07470.13 KIK70023.1 - 5e-15 55.4 0.1 7.3e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Amidase PF01425.21 KIK70024.1 - 1.3e-85 288.1 0.0 1.8e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 Amidase FbpC_C_terminal PF17845.1 KIK70024.1 - 0.076 13.1 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain zf-C5HC2 PF02928.16 KIK70026.1 - 0.0078 16.6 3.0 0.84 10.1 0.2 2.1 2 0 0 2 2 2 2 C5HC2 zinc finger FMN_red PF03358.15 KIK70027.1 - 1.7e-11 44.1 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIK70027.1 - 1.2e-05 25.1 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KIK70027.1 - 0.0023 18.2 0.0 0.063 13.5 0.0 2.4 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KIK70027.1 - 0.076 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.22 KIK70028.1 - 2.2e-20 72.2 0.0 2.3e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK70028.1 - 0.083 13.0 0.0 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Glycoprotein PF03409.15 KIK70029.1 - 0.0013 17.6 0.2 0.0024 16.8 0.0 1.5 2 0 0 2 2 2 1 Transmembrane glycoprotein Pro_isomerase PF00160.21 KIK70030.1 - 1.2e-46 158.9 0.6 1.3e-46 158.7 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAD-oxidase_C PF02913.19 KIK70030.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain OTCace PF00185.24 KIK70030.1 - 0.18 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain COesterase PF00135.28 KIK70031.1 - 4.4e-82 276.6 0.0 4.9e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK70031.1 - 1e-05 25.5 0.8 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK70031.1 - 0.06 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L18A PF01775.17 KIK70034.1 - 7.9e-57 190.6 0.8 9.7e-57 190.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Metallophos PF00149.28 KIK70035.1 - 3.2e-16 60.5 0.1 5.5e-16 59.7 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Rad60-SLD_2 PF13881.6 KIK70036.1 - 8.3e-15 54.9 0.1 3.1e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIK70036.1 - 0.00021 21.0 0.0 0.0018 18.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family FHA PF00498.26 KIK70037.1 - 4.7e-10 39.7 0.1 1.1e-09 38.5 0.0 1.8 2 1 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KIK70037.1 - 0.0049 17.2 0.0 0.0099 16.2 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain C2 PF00168.30 KIK70038.1 - 3.1e-21 75.6 0.0 2e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain Glyco_transf_90 PF05686.12 KIK70041.1 - 1.1e-16 60.7 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 90 APH PF01636.23 KIK70042.1 - 1.8e-13 51.0 0.0 2.6e-12 47.2 0.0 2.7 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pro_isomerase PF00160.21 KIK70043.1 - 4.6e-25 88.7 0.0 6.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Amidase PF01425.21 KIK70044.1 - 1.2e-85 288.2 0.0 1.4e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Amidase F-box-like PF12937.7 KIK70045.1 - 3.5e-08 33.2 0.5 3.5e-08 33.2 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK70045.1 - 1.5e-05 24.7 0.4 5.7e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIK70045.1 - 0.21 12.0 1.5 12 6.4 0.4 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF563 PF04577.14 KIK70046.1 - 2.9e-22 79.8 0.2 7.9e-22 78.4 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Gly-zipper_Omp PF13488.6 KIK70048.1 - 0.33 11.0 5.8 0.78 9.8 5.8 1.6 1 0 0 1 1 1 0 Glycine zipper MGC-24 PF05283.11 KIK70048.1 - 2.4 8.6 11.2 0.058 13.8 1.6 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PBP1_TM PF14812.6 KIK70050.1 - 2.4 8.6 10.5 2.1 8.8 8.6 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldo_ket_red PF00248.21 KIK70051.1 - 4.6e-44 150.8 0.0 6.2e-43 147.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK70052.1 - 1.4e-45 155.7 0.0 1.3e-44 152.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family GATA PF00320.27 KIK70053.1 - 1.5 8.5 5.9 2.4 7.8 2.4 2.7 2 0 0 2 2 2 0 GATA zinc finger Glyco_hydro_79C PF16862.5 KIK70054.1 - 5.4e-16 59.4 0.0 1.1e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KIK70054.1 - 0.02 13.9 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Bestrophin PF01062.21 KIK70055.1 - 4.2e-34 118.3 0.3 2.3e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel MotA_ExbB PF01618.16 KIK70055.1 - 0.16 11.7 1.1 0.28 10.9 0.3 1.7 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family CH PF00307.31 KIK70056.1 - 7.9e-75 248.1 0.0 4.9e-19 68.5 0.0 5.1 5 1 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KIK70056.1 - 9.1e-05 22.2 0.0 8.7 6.3 0.0 4.1 4 0 0 4 4 4 3 CAMSAP CH domain CH_2 PF06294.11 KIK70056.1 - 0.18 12.0 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF3341 PF11821.8 KIK70057.1 - 0.017 14.8 1.7 0.13 11.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF3421 PF11901.8 KIK70058.1 - 5.5e-27 94.0 0.0 9.3e-23 80.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Pkinase_Tyr PF07714.17 KIK70059.1 - 4.2e-58 196.7 0.0 5.3e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK70059.1 - 3.5e-48 164.3 0.0 4.6e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK70059.1 - 0.00098 18.8 0.2 0.002 17.8 0.2 1.5 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIK70059.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KIK70059.1 - 0.019 13.7 0.7 0.032 13.0 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase YuiB PF14068.6 KIK70060.1 - 0.063 13.9 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative membrane protein Glyco_hydro_79C PF16862.5 KIK70061.1 - 4.8e-19 69.2 0.1 1.1e-18 67.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KIK70061.1 - 9.3e-05 21.5 0.0 0.00022 20.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Pmp3 PF01679.17 KIK70063.1 - 6.4e-17 61.5 6.4 7.2e-17 61.3 6.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pyridoxal_deC PF00282.19 KIK70064.1 - 2.6e-66 223.9 0.0 3.4e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIK70064.1 - 0.00022 20.3 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V dCache_3 PF14827.6 KIK70064.1 - 0.0021 17.8 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Double sensory domain of two-component sensor kinase OKR_DC_1 PF01276.20 KIK70064.1 - 0.052 12.3 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain zf-RanBP PF00641.18 KIK70065.1 - 0.17 11.2 2.0 0.31 10.4 2.0 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GRIM-19 PF06212.12 KIK70068.1 - 8.1e-29 100.2 0.0 8.7e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Sugar_tr PF00083.24 KIK70069.1 - 5.3e-43 147.5 13.5 1.3e-42 146.2 13.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK70069.1 - 4.7e-21 75.1 24.1 2.9e-12 46.2 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK70070.1 - 6.5e-39 133.9 51.7 3.6e-37 128.1 51.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK70070.1 - 1.1e-19 70.3 28.3 1.6e-19 69.8 28.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK70070.1 - 5.7e-12 45.2 4.4 5.7e-12 45.2 4.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1158 PF06643.11 KIK70070.1 - 3 8.4 6.7 0.41 11.2 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1158) MFS_1 PF07690.16 KIK70071.1 - 9.1e-29 100.5 14.8 1.2e-28 100.1 14.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK70071.1 - 5.5e-13 48.6 4.2 6.5e-13 48.3 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK70071.1 - 5.8e-08 31.6 2.7 8.9e-08 31.0 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIK70071.1 - 0.05 11.9 2.8 0.1 10.9 2.8 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF832 PF05734.11 KIK70071.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) MFS_1 PF07690.16 KIK70072.1 - 6.4e-07 28.6 17.3 6.4e-07 28.6 17.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glycos_transf_1 PF00534.20 KIK70073.1 - 2.6e-26 92.2 0.0 4.8e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIK70073.1 - 1.5e-17 64.2 0.5 2.7e-17 63.3 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIK70073.1 - 1.9e-12 47.7 0.0 6.6e-11 42.8 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIK70073.1 - 1.3e-07 32.2 0.0 3.4e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIK70073.1 - 0.00037 20.8 0.0 0.00093 19.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_6 PF13174.6 KIK70073.1 - 0.13 13.0 0.0 0.4 11.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Endonuc_Holl PF10107.9 KIK70074.1 - 6.9 6.5 8.3 0.28 11.0 1.1 2.2 2 1 1 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase Coa1 PF08695.10 KIK70076.1 - 1e-33 115.6 0.1 1.4e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 KIK70076.1 - 0.0061 16.5 0.0 0.0094 15.8 0.0 1.4 1 1 0 1 1 1 1 TIM21 DUF4499 PF14934.6 KIK70077.1 - 0.07 13.5 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Fe_dep_repress PF01325.19 KIK70078.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF4470 PF14737.6 KIK70079.1 - 9.7e-23 80.2 0.0 1.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIK70079.1 - 8.7e-05 22.5 8.6 0.00018 21.6 8.6 1.6 1 0 0 1 1 1 1 MYND finger Citrate_bind PF16114.5 KIK70081.1 - 1.6e-89 298.1 0.2 3.2e-89 297.1 0.2 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KIK70081.1 - 3.9e-19 68.9 0.0 5.4e-16 58.6 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KIK70081.1 - 5.6e-14 52.2 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KIK70081.1 - 9.1e-09 35.9 0.0 4.6e-08 33.6 0.0 2.2 1 1 1 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 KIK70081.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KIK70081.1 - 2.2e-05 24.3 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF3147 PF11345.8 KIK70082.1 - 0.082 13.3 12.0 0.29 11.5 0.5 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3147) DUF2433 PF10360.9 KIK70083.1 - 5.2e-45 152.5 0.0 1.3e-44 151.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 KIK70083.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KIK70083.1 - 0.028 14.9 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK70083.1 - 0.043 14.0 0.0 0.16 12.2 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CDC45 PF02724.14 KIK70083.1 - 0.78 8.0 6.2 1.2 7.3 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mitofilin PF09731.9 KIK70083.1 - 1.1 8.0 16.2 2.3 7.0 16.2 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sec62 PF03839.16 KIK70083.1 - 4.4 6.8 4.4 8 5.9 4.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 AdoHcyase PF05221.17 KIK70085.1 - 1.7e-132 441.1 0.0 1.3e-72 244.5 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KIK70085.1 - 9.8e-84 279.3 0.4 1.4e-83 278.8 0.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIK70085.1 - 4.4e-06 26.2 0.0 8.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KIK70085.1 - 0.00058 19.5 0.1 0.00094 18.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KIK70085.1 - 0.0033 17.7 0.1 0.0072 16.6 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Mitochondr_Som1 PF11093.8 KIK70086.1 - 1.8e-09 37.5 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DUF4449 PF14613.6 KIK70088.1 - 1.3e-12 48.1 2.6 2.2e-11 44.1 0.0 3.7 2 2 1 4 4 4 1 Protein of unknown function (DUF4449) Apolipoprotein PF01442.18 KIK70088.1 - 0.0022 17.9 13.1 1 9.2 0.1 3.5 3 0 0 3 3 3 3 Apolipoprotein A1/A4/E domain Phage_GP20 PF06810.11 KIK70088.1 - 0.098 12.5 0.0 0.098 12.5 0.0 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 ABC_membrane_2 PF06472.15 KIK70089.1 - 1.3e-74 251.1 0.1 5.7e-74 248.9 0.1 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KIK70089.1 - 3.2e-13 50.4 0.0 6.8e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK70089.1 - 0.0093 16.4 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIK70089.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2768 PF10966.8 KIK70090.1 - 0.16 12.4 5.2 1.7 9.1 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) JAB PF01398.21 KIK70091.1 - 2.8e-14 53.1 0.0 4.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KIK70091.1 - 3.4e-10 40.1 0.0 6.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KIK70091.1 - 2.1e-07 30.7 0.0 6.9e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain IBR PF01485.21 KIK70092.1 - 2.8e-16 59.5 28.4 5.9e-09 36.0 2.8 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 KIK70092.1 - 7e-07 29.0 0.0 7.4e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 KIK70092.1 - 9e-06 25.5 8.9 9e-06 25.5 8.9 3.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK70092.1 - 1e-05 25.2 6.7 1e-05 25.2 6.7 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK70092.1 - 0.00012 22.0 7.7 0.00012 22.0 7.7 3.3 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK70092.1 - 0.006 16.9 9.0 0.006 16.9 9.0 4.1 3 1 0 3 3 3 1 Ring finger domain zf-Nse PF11789.8 KIK70092.1 - 0.012 15.4 3.1 0.054 13.3 3.1 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KIK70092.1 - 0.02 15.2 1.4 0.02 15.2 1.4 3.7 3 1 0 3 3 3 0 RING-H2 zinc finger domain zf_CCCH_4 PF18345.1 KIK70092.1 - 1.3 9.2 4.7 3.3 7.9 4.7 1.8 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 KIK70093.1 - 0.00022 21.9 0.0 0.00043 21.0 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 KIK70093.1 - 0.18 11.8 1.0 0.29 11.1 1.0 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK70093.1 - 0.63 10.2 4.9 1 9.5 4.9 1.4 1 0 0 1 1 1 0 Zinc finger domain ORC6 PF05460.13 KIK70093.1 - 0.81 8.9 7.5 0.88 8.8 7.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sod_Fe_C PF02777.18 KIK70094.1 - 1.1e-33 115.5 0.1 1.9e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIK70094.1 - 1e-17 64.3 2.9 1e-17 64.3 2.9 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Macro PF01661.21 KIK70095.1 - 4.8e-40 136.3 0.1 8.2e-40 135.5 0.1 1.4 1 0 0 1 1 1 1 Macro domain tRNA-synt_1b PF00579.25 KIK70096.1 - 2.5e-61 207.6 0.0 2.8e-60 204.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 KIK70100.1 - 0.0015 18.8 0.0 0.0028 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK70100.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK70100.1 - 0.0085 16.6 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KIK70100.1 - 0.0094 16.0 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK70100.1 - 0.011 16.2 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.21 KIK70100.1 - 0.039 13.6 0.0 0.083 12.6 0.0 1.5 2 0 0 2 2 2 0 Guanylate kinase Viral_helicase1 PF01443.18 KIK70100.1 - 0.053 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KIK70100.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK70100.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK70100.1 - 0.12 12.6 0.2 0.4 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK70100.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 KIK70100.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KIK70100.1 - 0.16 12.0 0.1 0.31 11.1 0.0 1.5 1 1 0 1 1 1 0 Dynamin family AAA PF00004.29 KIK70100.1 - 0.17 12.3 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIK70100.1 - 0.2 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA12 PF10443.9 KIK70100.1 - 0.21 10.3 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein cobW PF02492.19 KIK70100.1 - 0.22 11.1 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF3429 PF11911.8 KIK70101.1 - 0.011 16.0 1.0 0.011 16.0 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) Sulf_transp PF04143.14 KIK70101.1 - 0.25 10.8 5.0 0.4 10.2 5.0 1.2 1 0 0 1 1 1 0 Sulphur transport F-box-like PF12937.7 KIK70103.1 - 0.0016 18.3 0.1 0.005 16.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like adh_short PF00106.25 KIK70104.1 - 1.5e-28 99.6 0.0 2.3e-27 95.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK70104.1 - 7.4e-16 58.4 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK70104.1 - 1.6e-08 34.7 0.1 2.4e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KIK70104.1 - 0.0012 19.2 0.2 0.0027 18.1 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.21 KIK70104.1 - 0.0064 16.0 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK70104.1 - 0.037 13.9 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding YjeF_N PF03853.15 KIK70104.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus PA PF02225.22 KIK70104.1 - 0.17 12.0 0.3 0.37 10.9 0.3 1.6 1 0 0 1 1 1 0 PA domain GDP_Man_Dehyd PF16363.5 KIK70104.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KIK70104.1 - 0.35 10.9 1.3 0.88 9.6 1.1 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase EamA PF00892.20 KIK70105.1 - 7.6e-24 84.4 37.6 3.4e-15 56.4 12.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family Gemini_AC4_5_2 PF08464.10 KIK70105.1 - 0.11 12.5 0.7 3.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region RseC_MucC PF04246.12 KIK70105.1 - 1.1 9.2 9.0 0.095 12.7 0.6 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2070 PF09843.9 KIK70105.1 - 2.3 6.4 27.6 0.097 10.9 9.4 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) MIP PF00230.20 KIK70107.1 - 5.3e-29 101.5 8.2 7.3e-29 101.1 8.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 KIK70108.1 - 1.4e-30 106.5 31.8 1.4e-30 106.5 31.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Tetraspanin PF00335.20 KIK70108.1 - 3.6 7.2 6.7 6.5 6.4 0.6 3.1 4 0 0 4 4 4 0 Tetraspanin family IL6Ra-bind PF09240.10 KIK70109.1 - 0.009 16.4 0.7 0.011 16.1 0.7 1.2 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding DUF2034 PF10356.9 KIK70111.1 - 9.7e-25 87.1 0.2 9.6e-24 83.8 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KIK70111.1 - 1.7e-08 34.5 0.0 4.3e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease zf-C2H2 PF00096.26 KIK70114.1 - 1.1e-08 35.1 10.6 5.5e-05 23.4 1.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK70114.1 - 0.00013 22.2 4.0 0.00013 22.2 4.0 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK70114.1 - 0.023 15.5 1.7 0.023 15.5 1.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK70114.1 - 0.9 9.4 5.2 3.2 7.6 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Macoilin PF09726.9 KIK70115.1 - 2.9 6.4 9.7 0.038 12.6 2.4 1.4 2 0 0 2 2 2 0 Macoilin family RRF PF01765.19 KIK70116.1 - 6.1e-26 91.3 0.5 1.1e-25 90.5 0.5 1.4 1 0 0 1 1 1 1 Ribosome recycling factor NolV PF06635.12 KIK70116.1 - 0.049 13.0 0.5 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein NolV CDC14 PF08045.11 KIK70116.1 - 0.12 11.5 0.1 0.12 11.5 0.1 1.5 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Tma16 PF11176.8 KIK70116.1 - 0.7 9.8 5.3 1.7 8.5 0.2 2.8 3 0 0 3 3 3 0 Translation machinery-associated protein 16 SNF2_N PF00176.23 KIK70117.1 - 9.1e-59 198.9 1.4 2.1e-58 197.7 1.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK70117.1 - 2.3e-11 44.0 0.0 7.8e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KIK70117.1 - 5.1e-10 39.2 2.4 5.1e-10 39.2 2.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK70117.1 - 2e-08 33.9 7.7 5.4e-08 32.6 7.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK70117.1 - 3.1e-08 33.3 3.3 3.1e-08 33.3 3.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK70117.1 - 3.7e-07 30.0 6.6 7e-07 29.1 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK70117.1 - 5.8e-07 29.3 8.4 1.1e-06 28.3 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70117.1 - 2.6e-06 27.6 7.1 6.5e-06 26.4 7.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIK70117.1 - 3.8e-06 26.9 8.4 1.9e-05 24.7 8.5 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 KIK70117.1 - 1.4e-05 25.1 1.1 0.0001 22.4 0.4 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-Nse PF11789.8 KIK70117.1 - 0.019 14.8 6.2 0.042 13.7 6.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KIK70117.1 - 0.077 13.3 4.6 0.21 11.9 4.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIK70117.1 - 0.94 9.4 9.9 14 5.6 9.9 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIK70117.1 - 10 6.1 6.6 0.43 10.5 0.5 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 KIK70119.1 - 0.0006 19.6 7.3 0.001 18.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70119.1 - 0.0017 18.7 8.3 0.0027 18.0 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK70119.1 - 0.52 10.2 6.1 0.83 9.6 6.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK70119.1 - 1.8 8.5 9.1 2.7 7.9 9.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pap_E4 PF02711.14 KIK70119.1 - 3.8 8.6 8.7 4.6 8.3 3.1 2.8 3 0 0 3 3 3 0 E4 protein Methyltransf_24 PF13578.6 KIK70120.1 - 6.4e-11 43.2 0.0 1.2e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KIK70120.1 - 1e-05 24.9 0.0 2.5e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.16 KIK70121.1 - 1.7e-43 148.9 30.8 6.5e-43 147.0 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK70121.1 - 0.0011 17.9 26.3 0.0064 15.4 26.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter S10_plectin PF03501.15 KIK70121.1 - 0.024 14.7 0.5 0.042 13.9 0.5 1.3 1 0 0 1 1 1 0 Plectin/S10 domain WD40 PF00400.32 KIK70124.1 - 2.9e-44 148.2 16.8 3.2e-07 30.9 0.0 11.5 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70124.1 - 7.2e-25 87.1 0.0 0.00014 22.1 0.0 8.9 4 3 7 11 11 10 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KIK70124.1 - 1.5e-23 83.2 0.0 3e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KIK70124.1 - 3.8e-10 39.3 1.0 0.23 10.4 0.0 6.9 4 3 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 KIK70124.1 - 2.3e-05 24.1 0.1 0.32 10.5 0.0 4.2 4 1 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KIK70124.1 - 6.4e-05 22.8 6.4 0.33 10.9 0.1 6.3 7 0 0 7 7 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK70124.1 - 0.00031 20.2 1.7 5.8 6.2 0.0 5.1 3 2 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK70124.1 - 0.0036 17.1 0.0 0.42 10.3 0.0 3.5 3 2 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK70124.1 - 0.0054 15.4 0.1 3.3 6.3 0.0 3.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK70124.1 - 0.031 13.6 0.0 2.7 7.3 0.0 3.5 3 1 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KIK70124.1 - 0.034 12.7 0.1 15 4.0 0.0 3.6 4 0 0 4 4 4 0 Cytochrome D1 heme domain IKI3 PF04762.12 KIK70124.1 - 0.054 11.5 0.0 2.5 6.0 0.0 2.4 2 1 0 2 2 2 0 IKI3 family RAB3GAP2_N PF14655.6 KIK70124.1 - 0.083 12.1 0.0 3 7.0 0.0 3.4 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 KIK70124.1 - 9.8 6.8 13.0 6.5 7.4 0.2 5.0 5 1 1 6 6 5 0 PQQ-like domain p450 PF00067.22 KIK70125.1 - 2.8e-63 214.3 0.0 3.5e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIK70126.1 - 1.4e-08 34.5 0.5 3.2e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like Glyco_transf_15 PF01793.16 KIK70127.1 - 2.8e-122 408.0 9.4 3.6e-122 407.7 9.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Epimerase PF01370.21 KIK70128.1 - 2.2e-22 79.7 0.0 4.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK70128.1 - 2.3e-18 66.2 0.0 5.6e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK70128.1 - 3.8e-12 45.9 0.1 3.7e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KIK70128.1 - 3.6e-10 40.0 1.7 5.7e-10 39.4 1.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIK70128.1 - 3.1e-09 36.7 0.3 4.9e-09 36.0 0.3 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIK70128.1 - 4.8e-06 26.3 0.6 1.2e-05 25.0 0.7 1.5 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KIK70128.1 - 0.00096 19.1 1.0 0.0025 17.7 1.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK70128.1 - 0.0012 18.0 0.4 0.002 17.3 0.3 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK70128.1 - 0.06 12.8 0.1 0.41 10.1 0.1 2.4 2 1 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK70128.1 - 0.064 13.5 0.2 0.16 12.3 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_16 PF10294.9 KIK70129.1 - 2.5e-08 33.9 0.0 3.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase SurA_N_3 PF13624.6 KIK70130.1 - 0.1 12.4 0.8 0.19 11.5 0.2 1.6 1 1 0 1 1 1 0 SurA N-terminal domain Aminotran_1_2 PF00155.21 KIK70132.1 - 3.3e-29 102.2 0.0 4.3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribonuclease PF00545.20 KIK70135.1 - 6.7e-07 30.0 0.0 1e-06 29.4 0.0 1.3 1 0 0 1 1 1 1 ribonuclease Aldolase_II PF00596.21 KIK70136.1 - 5e-36 124.4 0.0 6.5e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-MYND PF01753.18 KIK70137.1 - 7.3e-10 38.8 13.7 1.7e-09 37.6 13.7 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK70137.1 - 0.084 13.2 11.8 0.22 11.9 11.8 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CBFD_NFYB_HMF PF00808.23 KIK70138.1 - 1.1e-26 92.9 0.3 1.7e-26 92.3 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK70138.1 - 0.00059 20.2 0.0 0.00085 19.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KIK70138.1 - 0.0054 16.7 0.0 0.0085 16.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KIK70138.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PAN_3 PF08277.12 KIK70138.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain TFIID_20kDa PF03847.13 KIK70138.1 - 0.15 12.6 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A ADH_N PF08240.12 KIK70140.1 - 1.1e-29 102.5 0.2 1.8e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK70140.1 - 2.3e-10 40.6 0.2 5.8e-10 39.2 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK70140.1 - 5e-06 26.2 0.0 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KIK70140.1 - 1.2e-05 25.1 0.1 3.5e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KIK70140.1 - 0.0007 19.0 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIK70140.1 - 0.00073 18.3 0.4 0.0033 16.2 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KIK70140.1 - 0.062 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KIK70140.1 - 0.072 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK70140.1 - 0.14 11.2 0.4 0.2 10.7 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KIK70140.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KIK70140.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kelch_4 PF13418.6 KIK70141.1 - 8e-29 99.4 3.5 9.1e-07 28.8 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KIK70141.1 - 2.9e-25 88.0 8.8 3e-07 30.6 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF4110 PF13422.6 KIK70141.1 - 2.1e-20 72.6 0.2 2.1e-20 72.6 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 KIK70141.1 - 7e-20 70.6 8.4 3.2e-06 27.2 0.2 5.0 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KIK70141.1 - 1.9e-17 62.6 6.9 1.1e-06 28.1 0.0 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KIK70141.1 - 1.8e-16 59.7 9.2 0.00044 20.2 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KIK70141.1 - 1.2e-13 50.4 13.7 2.1e-05 24.3 0.1 6.2 5 1 0 5 5 5 3 Kelch motif DUF2508 PF10704.9 KIK70141.1 - 0.063 13.5 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) RPN1_RPN2_N PF17781.1 KIK70142.1 - 4.8e-114 380.9 0.0 7.9e-114 380.2 0.0 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KIK70142.1 - 4.3e-30 103.5 0.1 9.7e-30 102.4 0.1 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KIK70142.1 - 3.1e-25 87.3 17.9 1.2e-07 31.8 0.1 8.4 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIK70142.1 - 3.5e-07 30.5 0.2 0.01 16.2 0.1 4.5 4 1 1 5 5 5 3 HEAT repeats Cyclin_N PF00134.23 KIK70143.1 - 3.6e-42 143.1 0.5 4.3e-41 139.6 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK70143.1 - 8.7e-26 90.3 0.2 1.8e-25 89.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DDE_1 PF03184.19 KIK70143.1 - 0.0074 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Aminotran_5 PF00266.19 KIK70144.1 - 2.3e-14 53.1 0.0 7.5e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIK70144.1 - 7.8e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 KIK70144.1 - 0.022 13.5 0.2 0.073 11.8 0.2 1.8 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Lon_C PF05362.13 KIK70145.1 - 1.1e-66 224.4 0.8 2e-66 223.5 0.4 1.7 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KIK70145.1 - 4.4e-32 111.7 0.1 1.1e-31 110.3 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KIK70145.1 - 2e-21 76.8 0.0 5.4e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK70145.1 - 9.2e-06 26.1 0.1 3.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ChlI PF13541.6 KIK70145.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KIK70145.1 - 7.5e-05 22.8 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK70145.1 - 0.00013 22.2 0.1 0.0021 18.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIK70145.1 - 0.0024 18.0 0.0 0.0057 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KIK70145.1 - 0.006 17.1 1.4 0.0094 16.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK70145.1 - 0.0069 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK70145.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIK70145.1 - 0.018 15.4 0.0 0.089 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 KIK70145.1 - 0.031 14.0 0.0 0.14 11.9 0.0 2.0 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIK70145.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 KIK70145.1 - 0.071 13.2 0.9 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 KIK70145.1 - 0.097 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK70145.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KIK70145.1 - 0.17 11.9 0.0 0.68 10.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain DUF4231 PF14015.6 KIK70147.1 - 4.3 7.9 8.5 0.45 11.0 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Cyclin_N PF00134.23 KIK70148.1 - 8.1e-33 112.9 0.3 2.1e-32 111.6 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK70148.1 - 9.6e-24 83.8 0.1 4.3e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain DSPc PF00782.20 KIK70149.1 - 2.7e-05 24.0 0.2 0.00012 21.9 0.0 2.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KIK70149.1 - 0.015 15.5 0.1 0.056 13.5 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 KIK70149.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KIK70149.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Mito_carr PF00153.27 KIK70150.1 - 3.2e-57 190.5 1.4 2.6e-21 75.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein G-alpha PF00503.20 KIK70151.1 - 1.9e-105 352.9 0.0 2.3e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK70151.1 - 5.1e-10 39.1 0.0 7.2e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK70151.1 - 0.00083 19.6 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK70151.1 - 0.014 15.2 0.0 0.042 13.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KIK70151.1 - 0.057 12.8 0.2 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 KIK70151.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein La PF05383.17 KIK70152.1 - 1.6e-06 28.0 0.0 3.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 La domain MCM6_C PF18263.1 KIK70152.1 - 0.04 14.2 0.8 0.062 13.5 0.7 1.3 1 1 0 1 1 1 0 MCM6 C-terminal winged-helix domain Myc_N PF01056.18 KIK70152.1 - 0.18 11.6 1.4 0.18 11.6 1.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CBS PF00571.28 KIK70154.1 - 9.7e-09 35.5 0.0 0.00021 21.7 0.0 2.6 2 1 1 3 3 3 2 CBS domain RRXRR PF14239.6 KIK70154.1 - 0.16 11.8 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 RRXRR protein Pmp3 PF01679.17 KIK70156.1 - 7.4e-25 86.9 11.1 9.2e-25 86.6 11.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RdRP PF05183.12 KIK70157.1 - 5e-119 398.6 0.0 6.7e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DpnI_C PF17726.1 KIK70157.1 - 0.051 13.7 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 Dam-replacing HTH domain PRANC PF09372.10 KIK70159.1 - 0.0025 18.1 0.1 0.014 15.7 0.1 2.2 2 0 0 2 2 2 1 PRANC domain G-alpha PF00503.20 KIK70160.1 - 3.1e-97 325.9 0.0 1.3e-96 323.9 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK70160.1 - 3.3e-07 29.9 0.0 7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK70160.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ADH_zinc_N PF00107.26 KIK70162.1 - 9.9e-13 48.2 0.8 1.6e-12 47.5 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK70162.1 - 9.8e-08 31.9 0.9 4.2e-07 29.8 0.4 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK70162.1 - 0.00067 20.7 0.0 0.0017 19.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Mlh1_C PF16413.5 KIK70163.1 - 2.2e-92 309.3 0.2 5.9e-92 307.9 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KIK70163.1 - 1.4e-29 102.2 0.2 2.3e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIK70163.1 - 1.8e-11 44.0 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK70163.1 - 2.3e-07 31.3 0.0 5.7e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HV_small_capsid PF17086.5 KIK70163.1 - 0.18 12.1 1.1 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Small capsid protein of Herpesviridae Mlh1_C PF16413.5 KIK70165.1 - 9.1e-25 87.5 0.0 1.1e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus His_Phos_2 PF00328.22 KIK70166.1 - 2.5e-17 63.3 0.1 9e-07 28.6 0.0 4.2 4 1 1 5 5 5 3 Histidine phosphatase superfamily (branch 2) Peptidase_C58 PF03543.14 KIK70167.1 - 6.2e-05 22.8 0.2 0.00012 21.8 0.2 1.4 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen SMC_N PF02463.19 KIK70168.1 - 1.5e-58 197.9 32.7 1.1e-32 113.3 12.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIK70168.1 - 5.8e-18 65.3 3.1 1.6e-17 63.9 0.1 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIK70168.1 - 3.4e-09 36.9 18.8 7.6e-06 25.9 0.1 4.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK70168.1 - 0.00013 21.6 0.1 0.0004 20.1 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK70168.1 - 0.0018 18.0 22.0 0.0018 18.0 22.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KIK70168.1 - 0.0054 17.3 49.6 0.0054 17.3 49.6 7.2 2 2 2 4 4 4 1 AAA domain DAO PF01266.24 KIK70169.1 - 5.1e-40 138.1 0.1 6e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK70169.1 - 8.6e-05 22.7 0.1 0.00021 21.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK70169.1 - 0.00024 20.4 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KIK70169.1 - 0.00078 19.5 0.1 0.0042 17.1 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 KIK70169.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_2 PF07992.14 KIK70169.1 - 0.023 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK70169.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK70169.1 - 0.15 11.1 0.1 0.59 9.1 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein zf-C3HC4_3 PF13920.6 KIK70170.1 - 2.2e-06 27.4 3.1 3.5e-06 26.8 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK70170.1 - 6.5e-06 26.0 3.2 1e-05 25.4 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK70170.1 - 0.00019 21.3 4.4 0.00031 20.6 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70170.1 - 0.0029 17.9 4.5 0.0048 17.2 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK70170.1 - 0.0046 16.8 4.3 0.0086 15.9 4.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK70170.1 - 0.0056 16.7 3.2 0.011 15.7 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger RRM_1 PF00076.22 KIK70170.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.6 KIK70170.1 - 0.22 11.4 3.1 0.39 10.5 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KIK70170.1 - 0.5 10.3 4.2 0.88 9.5 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK70170.1 - 0.59 10.3 2.1 1.3 9.2 2.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.27 KIK70172.1 - 5.3e-52 173.7 6.7 2.4e-18 65.8 0.0 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KIK70173.1 - 1.3e-26 93.2 0.1 2.5e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIK70174.1 - 4.4e-24 85.0 0.0 7e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK70174.1 - 5.6e-08 32.8 12.9 9.5e-08 32.0 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK70176.1 - 9.3e-24 83.9 0.2 2.3e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK70176.1 - 2.2e-08 34.1 11.5 3.5e-08 33.4 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Git3 PF11710.8 KIK70177.1 - 4.6e-07 29.8 4.2 4.6e-07 29.8 4.2 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KIK70177.1 - 5.3e-06 25.8 5.1 8.8e-06 25.1 5.1 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KIK70177.1 - 0.0025 17.1 7.1 0.0029 16.9 6.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) AMP-binding PF00501.28 KIK70178.1 - 7.7e-76 255.4 0.5 2.6e-61 207.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KIK70178.1 - 2.1e-11 44.6 0.0 7.9e-11 42.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HhH-GPD PF00730.25 KIK70180.1 - 2.1e-18 66.8 0.0 3.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KIK70180.1 - 3.9e-12 46.1 0.0 2.1e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 KIK70180.1 - 0.00071 19.3 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KIK70180.1 - 0.038 14.3 5.7 0.074 13.4 5.7 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Gti1_Pac2 PF09729.9 KIK70181.1 - 7e-27 94.7 0.1 1.9e-23 83.5 0.2 2.3 2 0 0 2 2 2 2 Gti1/Pac2 family DUF155 PF02582.14 KIK70182.1 - 5.7e-47 160.1 0.0 1.2e-46 159.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CorA PF01544.18 KIK70182.1 - 0.15 11.3 0.6 0.3 10.3 0.4 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Sec5 PF15469.6 KIK70183.1 - 5e-54 183.0 0.0 3e-53 180.5 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Sec15 PF04091.12 KIK70183.1 - 0.0086 15.5 0.0 0.036 13.5 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 KIK70183.1 - 0.087 12.9 0.2 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 Vps51/Vps67 HMG-CoA_red PF00368.18 KIK70184.1 - 2.6e-142 474.2 5.0 3.4e-142 473.8 5.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KIK70184.1 - 7.5e-12 45.3 0.8 1.8e-11 44.1 0.8 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIK70184.1 - 0.017 13.2 0.7 0.025 12.7 0.7 1.1 1 0 0 1 1 1 0 Patched family Herpes_LMP1 PF05297.11 KIK70184.1 - 0.89 8.7 3.7 1.6 7.9 3.7 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosomal_L44 PF00935.19 KIK70185.1 - 3e-37 127.0 12.4 4.8e-37 126.3 12.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 KIK70185.1 - 0.016 15.5 1.1 0.032 14.6 1.1 1.4 1 0 0 1 1 1 0 Cathelicidin NARP1 PF12569.8 KIK70186.1 - 3.7e-155 517.8 17.5 2.1e-153 511.9 10.2 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 KIK70186.1 - 3.3e-09 36.2 0.3 0.0026 17.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK70186.1 - 1.4e-08 34.2 2.5 0.00097 18.9 0.2 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK70186.1 - 1.5e-08 34.1 25.9 0.0095 16.0 0.0 9.6 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK70186.1 - 3.8e-08 33.5 14.4 1.4 9.9 0.0 9.6 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK70186.1 - 5.3e-08 33.3 15.8 0.14 12.7 0.6 7.4 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK70186.1 - 9.5e-08 32.6 15.3 9.5 7.0 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK70186.1 - 9.5e-05 22.5 4.6 1.2 9.3 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK70186.1 - 0.00014 21.5 6.1 0.0011 18.6 0.2 4.5 5 0 0 5 5 5 1 TPR repeat ANAPC3 PF12895.7 KIK70186.1 - 0.00032 20.9 1.9 0.7 10.2 0.0 4.7 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIK70186.1 - 0.0013 18.6 7.4 3.1 8.0 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK70186.1 - 0.0024 18.1 0.0 0.32 11.5 0.0 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK70186.1 - 0.0035 17.6 18.1 1.5 9.1 0.0 6.3 5 3 0 5 5 4 3 Tetratricopeptide repeat ATP13 PF12921.7 KIK70186.1 - 0.0095 15.8 0.1 6.1 6.7 0.0 4.7 6 0 0 6 6 6 1 Mitochondrial ATPase expression HTH_20 PF12840.7 KIK70186.1 - 0.35 10.9 3.1 19 5.4 0.0 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain TPR_6 PF13174.6 KIK70186.1 - 2.8 8.8 12.6 39 5.2 0.1 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.12 KIK70187.1 - 4e-19 68.8 0.0 1.1e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 90 ADH_N PF08240.12 KIK70189.1 - 6.5e-33 112.9 2.8 1.1e-32 112.1 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK70189.1 - 4.3e-15 55.8 0.0 7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK70189.1 - 2.3e-12 46.9 0.0 3.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK70189.1 - 7.8e-07 30.2 0.0 1.4e-06 29.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KIK70189.1 - 3.4e-05 23.3 0.9 4.9e-05 22.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KIK70189.1 - 0.037 12.7 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK70189.1 - 0.05 13.9 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KIK70189.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIK70189.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase tRNA-synt_1 PF00133.22 KIK70190.1 - 7.9e-154 513.2 0.0 9.4e-154 512.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK70190.1 - 5.2e-22 78.4 0.2 1.1e-21 77.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIK70190.1 - 3.4e-20 72.2 0.0 2.9e-14 52.6 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIK70190.1 - 0.0012 18.2 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KIK70190.1 - 0.013 15.3 7.7 0.027 14.3 7.7 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS CoaE PF01121.20 KIK70191.1 - 4e-59 199.3 0.0 4.9e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KIK70191.1 - 4.5e-06 27.2 0.0 7.1e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIK70191.1 - 0.00014 22.3 0.0 0.0015 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIK70191.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_16 PF00722.21 KIK70192.1 - 0.0031 17.0 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ChlamPMP_M PF07548.11 KIK70192.1 - 0.074 13.0 0.6 0.11 12.4 0.6 1.3 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain SURF4 PF02077.15 KIK70193.1 - 4.9e-97 324.7 6.6 5.6e-97 324.5 6.6 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 KIK70193.1 - 0.082 12.9 2.4 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5562) Cnd1 PF12717.7 KIK70195.1 - 2.7e-06 27.5 9.5 4.2e-05 23.6 0.2 4.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK70195.1 - 4.2e-05 23.9 3.7 0.024 15.0 0.3 5.3 5 2 0 5 5 5 1 HEAT repeats HEAT PF02985.22 KIK70195.1 - 4.6e-05 23.3 3.8 12 6.5 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KIK70195.1 - 0.048 14.2 3.2 5.9 7.5 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIK70195.1 - 0.21 12.2 11.2 0.73 10.5 0.8 5.2 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region ATP-cone PF03477.16 KIK70195.1 - 0.23 12.0 3.1 28 5.4 0.0 4.0 4 0 0 4 4 4 0 ATP cone domain DUF676 PF05057.14 KIK70196.1 - 1.6e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KIK70196.1 - 0.0011 18.3 0.0 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK70196.1 - 0.0023 18.6 7.2 0.0083 16.7 7.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KIK70196.1 - 0.0028 17.0 0.1 0.78 9.0 0.0 2.5 3 0 0 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 KIK70196.1 - 0.0046 16.8 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KIK70196.1 - 0.013 15.3 0.2 0.032 14.0 0.2 1.6 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 KIK70196.1 - 0.028 14.3 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KIK70196.1 - 0.051 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KIK70196.1 - 0.071 12.7 0.0 2.2 7.9 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KIK70196.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Acetyltransf_1 PF00583.25 KIK70197.1 - 1.2e-13 51.3 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK70197.1 - 4.6e-11 42.8 0.0 5.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK70197.1 - 4e-09 36.8 0.0 5.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK70197.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIK70197.1 - 2.4e-05 24.4 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIK70197.1 - 0.0046 16.5 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase AP_endonuc_2 PF01261.24 KIK70198.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SARS_3b PF12383.8 KIK70199.1 - 0.13 12.3 6.3 0.041 14.0 3.2 1.7 2 0 0 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein F-box-like PF12937.7 KIK70200.1 - 3.2e-06 26.9 0.0 7.1e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 F-box-like RuvB_N PF05496.12 KIK70200.1 - 0.012 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain F-box PF00646.33 KIK70200.1 - 0.058 13.3 2.0 1 9.3 2.0 2.3 1 1 0 1 1 1 0 F-box domain Sipho_Gp157 PF05565.11 KIK70200.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 F-box-like PF12937.7 KIK70201.1 - 6.1e-09 35.6 2.3 8.2e-09 35.2 0.9 2.0 2 0 0 2 2 2 1 F-box-like Ins134_P3_kin_N PF17927.1 KIK70201.1 - 0.13 12.6 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Sipho_Gp157 PF05565.11 KIK70201.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 RuvB_N PF05496.12 KIK70201.1 - 0.19 11.4 0.0 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NUC153 PF08159.12 KIK70202.1 - 7.4e-12 44.9 0.2 1.7e-11 43.7 0.2 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KIK70202.1 - 0.0035 18.2 0.2 2.1 9.4 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70202.1 - 0.049 13.9 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_5 PF13909.6 KIK70203.1 - 4.7e-11 42.2 8.8 2.1e-05 24.2 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK70203.1 - 1.5e-08 34.6 12.3 0.00091 19.6 0.4 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK70203.1 - 1.5e-06 28.5 8.5 0.062 14.2 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger GAGA PF09237.11 KIK70203.1 - 0.00095 18.9 0.0 0.00095 18.9 0.0 2.4 3 0 0 3 3 3 1 GAGA factor zf-H2C2_2 PF13465.6 KIK70203.1 - 0.042 14.3 14.8 0.045 14.2 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 KIK70203.1 - 0.1 12.3 1.5 2.1 8.0 0.0 2.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain PRP21_like_P PF12230.8 KIK70203.1 - 0.13 12.1 0.5 0.82 9.5 0.1 2.1 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein IBR PF01485.21 KIK70203.1 - 0.46 10.8 7.9 0.22 11.8 3.5 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 KIK70203.1 - 3.7 7.6 4.9 4.4 7.3 0.6 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF1479 PF07350.12 KIK70204.1 - 1.4e-143 478.7 0.0 1.6e-143 478.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KIK70204.1 - 0.058 13.6 0.1 1 9.5 0.0 3.0 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.25 KIK70205.1 - 2e-13 50.3 0.1 2.9e-12 46.5 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK70205.1 - 1.9e-11 44.0 0.1 8.5e-11 41.9 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK70205.1 - 0.031 14.2 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 KIK70207.1 - 1.5e-55 188.3 2.5 1.8e-55 188.0 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70207.1 - 2.2e-48 164.3 1.5 2.9e-48 163.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70207.1 - 6.5e-08 32.7 0.9 1.1e-07 31.9 0.9 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK70208.1 - 2.2e-56 191.0 3.4 2.6e-56 190.8 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70208.1 - 4.4e-49 166.6 3.3 5.4e-49 166.3 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70208.1 - 1.8e-07 31.2 2.1 3.2e-07 30.4 2.1 1.5 1 1 0 1 1 1 1 KR domain Acetyltransf_3 PF13302.7 KIK70209.1 - 0.0024 18.5 0.0 0.0057 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HLH PF00010.26 KIK70210.1 - 4.6e-10 39.3 0.0 1.2e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain YL1 PF05764.13 KIK70210.1 - 0.042 14.0 0.9 0.098 12.8 0.9 1.6 1 0 0 1 1 1 0 YL1 nuclear protein DUF4611 PF15387.6 KIK70210.1 - 0.11 12.7 4.5 0.35 11.1 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glycolytic PF00274.19 KIK70210.1 - 0.14 10.8 0.1 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I AT_hook PF02178.19 KIK70210.1 - 4.1 7.6 10.2 13 6.1 10.2 2.0 1 0 0 1 1 1 0 AT hook motif Oxidored_FMN PF00724.20 KIK70211.1 - 5.2e-94 315.3 0.0 5.9e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pro-kuma_activ PF09286.11 KIK70212.1 - 1.6e-31 109.5 0.0 4.5e-31 108.1 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK70212.1 - 1.8e-08 34.0 1.8 3e-08 33.3 1.8 1.3 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KIK70213.1 - 4.3e-33 114.6 0.0 1.8e-32 112.6 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK70213.1 - 2.1e-09 37.1 4.8 4.2e-09 36.1 4.8 1.4 1 0 0 1 1 1 1 Subtilase family BNIP2 PF12496.8 KIK70214.1 - 0.14 12.5 2.1 0.35 11.3 2.1 1.7 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Oxidored_FMN PF00724.20 KIK70216.1 - 3.3e-96 322.5 0.0 3.8e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KIK70218.1 - 7.3e-96 321.4 0.0 8.3e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ApoO PF09769.9 KIK70219.1 - 7.6e-31 106.8 0.5 9.5e-29 100.0 0.0 2.3 2 0 0 2 2 2 2 Apolipoprotein O Apolipoprotein PF01442.18 KIK70219.1 - 3e-06 27.3 2.4 0.0022 17.9 1.9 2.4 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KIK70219.1 - 0.1 13.2 6.2 9.6 6.9 4.7 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 KIK70219.1 - 0.27 11.2 10.9 0.79 9.7 0.1 2.4 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) COG2 PF06148.11 KIK70219.1 - 0.48 10.5 5.2 0.22 11.6 2.4 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KIK70219.1 - 0.63 10.3 6.8 28 5.1 3.9 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Oleosin PF01277.17 KIK70219.1 - 4.2 7.2 5.4 2.2 8.1 0.8 2.4 2 0 0 2 2 2 0 Oleosin 3Beta_HSD PF01073.19 KIK70220.1 - 1.3e-31 109.6 0.0 3.5e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK70220.1 - 1.2e-14 54.1 0.0 1.2e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KIK70220.1 - 1.6e-11 44.2 0.0 3.5e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIK70220.1 - 3.6e-06 27.0 0.0 7.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK70220.1 - 1.6e-05 24.2 0.0 2.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK70220.1 - 2e-05 24.1 0.3 5.6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIK70220.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK70220.1 - 0.0037 16.4 0.0 0.0096 15.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KIK70220.1 - 0.03 14.6 0.4 0.7 10.2 0.0 2.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain PGF-CTERM PF18204.1 KIK70220.1 - 3.4 7.8 4.6 2.9 8.0 2.5 2.1 2 0 0 2 2 2 0 PGF-CTERM motif Synthase_beta PF11421.8 KIK70221.1 - 1.1 10.0 9.8 3.4 8.4 9.8 2.0 1 1 0 1 1 1 0 ATP synthase F1 beta subunit 3Beta_HSD PF01073.19 KIK70223.1 - 3.3e-27 95.2 0.0 2.2e-26 92.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK70223.1 - 1.3e-11 44.2 0.0 1.4e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KIK70223.1 - 5.8e-09 35.8 0.0 1.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK70223.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIK70223.1 - 0.0043 16.2 0.0 0.0093 15.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIK70223.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.8 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KIK70223.1 - 0.22 10.9 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Macoilin PF09726.9 KIK70224.1 - 0.0013 17.4 23.7 0.0013 17.4 23.7 2.1 2 0 0 2 2 2 1 Macoilin family ATG16 PF08614.11 KIK70224.1 - 0.0038 17.5 32.3 0.0038 17.5 32.3 3.5 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KIK70224.1 - 0.024 12.2 24.1 0.047 11.2 24.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Arylsulfotran_N PF17425.2 KIK70224.1 - 0.06 13.4 0.0 0.28 11.2 0.0 2.1 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain CALCOCO1 PF07888.11 KIK70224.1 - 0.87 8.4 34.1 1.5 7.6 34.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMPIT PF07851.13 KIK70224.1 - 1.4 8.1 27.1 2.2 7.5 6.5 2.2 2 0 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 KIK70224.1 - 3 7.9 22.9 0.58 10.2 14.6 3.3 1 1 1 3 3 3 0 Laminin Domain II DUF4407 PF14362.6 KIK70224.1 - 3.1 7.1 27.3 12 5.2 5.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KIK70224.1 - 4.2 6.7 34.7 31 3.9 34.7 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 5 NUDIX PF00293.28 KIK70225.1 - 2.7e-10 40.4 0.0 3.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain YwiC PF14256.6 KIK70226.1 - 1.1 9.6 9.5 0.84 10.0 3.6 2.3 2 0 0 2 2 2 0 YwiC-like protein DAO PF01266.24 KIK70227.1 - 5.3e-33 115.0 0.1 6.4e-33 114.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KIK70227.1 - 0.031 13.8 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 KIK70227.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK70227.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIK70229.1 - 3.1e-67 226.7 0.0 4e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70229.1 - 1.7e-27 96.3 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK70229.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain AAA_28 PF13521.6 KIK70230.1 - 1.2e-22 80.9 0.0 1.5e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK70230.1 - 0.00021 21.7 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK70230.1 - 0.00031 21.3 0.0 0.00042 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK70230.1 - 0.0011 19.5 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KIK70230.1 - 0.0017 17.6 0.1 0.0022 17.3 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain MMR_HSR1 PF01926.23 KIK70230.1 - 0.0036 17.4 0.1 0.011 15.9 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK70230.1 - 0.0042 17.4 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KIK70230.1 - 0.0043 16.8 1.5 0.013 15.2 1.5 1.8 1 1 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 KIK70230.1 - 0.0047 17.1 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK70230.1 - 0.0049 17.4 0.0 0.006 17.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 KIK70230.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 KIK70230.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KIK70230.1 - 0.021 14.9 0.0 0.021 14.9 0.0 1.3 1 1 0 1 1 1 0 Dynamin family AAA_14 PF13173.6 KIK70230.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KIK70230.1 - 0.034 14.3 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Thymidylate_kin PF02223.17 KIK70230.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Thymidylate kinase SRPRB PF09439.10 KIK70230.1 - 0.06 12.8 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KIK70230.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KIK70230.1 - 0.084 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KIK70230.1 - 0.093 12.6 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase Cytidylate_kin2 PF13189.6 KIK70230.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family GTP_EFTU PF00009.27 KIK70230.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KIK70230.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK70230.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 KIK70230.1 - 0.17 12.4 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RdRP PF05183.12 KIK70231.1 - 1e-108 364.5 0.0 1.4e-108 364.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ADH_N PF08240.12 KIK70232.1 - 8.9e-34 115.7 1.9 2e-33 114.5 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK70232.1 - 1.3e-16 60.7 0.0 3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK70232.1 - 1.1e-09 38.1 0.1 1.7e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KIK70232.1 - 6.3e-05 22.4 0.4 8.9e-05 21.9 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.6 KIK70232.1 - 0.00021 22.4 0.0 0.0004 21.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KIK70232.1 - 0.0043 16.3 0.2 0.65 9.2 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_3 PF03447.16 KIK70232.1 - 0.013 16.2 0.4 0.12 13.1 0.1 2.7 3 1 1 4 4 4 0 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIK70232.1 - 0.091 13.0 0.8 0.17 12.1 0.2 1.9 2 1 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 KIK70232.1 - 0.15 12.1 0.3 0.33 11.0 0.3 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KIK70232.1 - 0.34 10.1 2.2 0.35 10.1 0.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2704 PF10866.8 KIK70234.1 - 0.11 12.4 0.7 0.18 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) GST_N PF02798.20 KIK70235.1 - 1.2e-16 60.8 0.1 7.5e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK70235.1 - 1.5e-11 44.5 0.0 4.6e-11 43.0 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK70235.1 - 1.4e-09 38.1 0.0 4.2e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK70235.1 - 2.4e-05 24.3 0.0 5.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK70235.1 - 0.0002 21.5 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK70235.1 - 0.00023 21.3 0.0 0.00056 20.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.28 KIK70236.1 - 1.1e-69 235.1 0.4 3.9e-69 233.3 0.4 1.8 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK70236.1 - 1.7e-64 217.5 0.0 2.9e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KIK70236.1 - 5.6e-07 28.9 0.0 2e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK70236.1 - 1.2e-05 24.9 0.0 3.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KIK70236.1 - 3.8e-05 24.6 0.0 0.00015 22.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIK70236.1 - 0.00023 21.4 0.0 0.00064 20.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Mucin PF01456.17 KIK70237.1 - 0.27 11.2 11.9 0.7 9.9 11.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein PAS_3 PF08447.12 KIK70238.1 - 0.099 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold TcdA_TcdB_pore PF12920.7 KIK70239.1 - 6.6e-176 586.4 0.1 9.3e-176 585.9 0.1 1.2 1 0 0 1 1 1 1 TcdA/TcdB pore forming domain Peptidase_C58 PF03543.14 KIK70239.1 - 0.0007 19.4 1.5 0.0012 18.6 0.2 2.0 2 0 0 2 2 2 1 Yersinia/Haemophilus virulence surface antigen adh_short_C2 PF13561.6 KIK70240.1 - 6.2e-58 196.1 1.6 7.2e-58 195.9 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70240.1 - 5.8e-49 166.2 0.4 9.1e-49 165.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70240.1 - 1.3e-08 35.0 0.1 2.5e-08 34.1 0.1 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KIK70240.1 - 0.024 14.1 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SBBP PF06739.11 KIK70240.1 - 0.029 14.4 0.3 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 Beta-propeller repeat Epimerase PF01370.21 KIK70240.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIK70240.1 - 0.19 11.6 0.2 0.93 9.4 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KIK70241.1 - 3.1e-17 63.1 0.0 4.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 KIK70243.1 - 4.7e-05 22.9 0.1 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 KIK70243.1 - 0.008 15.8 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KIK70243.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK70243.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.6 KIK70244.1 - 1e-08 35.3 2.6 0.0001 22.5 0.5 2.2 1 1 2 3 3 3 3 Tetratricopeptide repeat V-SNARE_C PF12352.8 KIK70244.1 - 0.0062 16.8 0.0 2.8 8.3 0.0 3.0 1 1 2 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus SNAP PF14938.6 KIK70244.1 - 0.014 14.8 0.5 0.016 14.7 0.5 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.9 KIK70244.1 - 0.063 12.7 0.0 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR NRN1 PF15056.6 KIK70244.1 - 0.11 12.6 0.2 10 6.3 0.0 2.3 1 1 1 2 2 2 0 Neuritin protein family JTB PF05439.12 KIK70245.1 - 0.0027 17.7 0.8 0.0042 17.1 0.1 1.6 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) DUF3678 PF12435.8 KIK70245.1 - 0.72 9.3 6.2 1.7 8.1 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) SRP19 PF01922.17 KIK70246.1 - 7.3e-26 90.9 0.0 1.1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein COesterase PF00135.28 KIK70247.1 - 8.7e-57 193.1 0.0 5.9e-56 190.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK70247.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.10 KIK70247.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Glyco_hydro_18 PF00704.28 KIK70248.1 - 6.4e-58 196.9 1.1 7.8e-58 196.6 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.7 KIK70250.1 - 5.2e-05 23.1 2.8 5.3e-05 23.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK70250.1 - 0.0055 16.6 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain BCNT PF07572.12 KIK70252.1 - 2.3e-17 62.8 0.2 4.9e-17 61.8 0.2 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development adh_short PF00106.25 KIK70259.1 - 1.3e-22 80.2 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK70259.1 - 3.7e-18 66.0 0.0 4.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK70259.1 - 7.2e-08 32.6 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1128 PF06569.11 KIK70259.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Epimerase PF01370.21 KIK70259.1 - 0.051 13.0 0.1 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TFIIA_gamma_N PF02268.16 KIK70260.1 - 3.3e-25 87.8 0.1 4.6e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KIK70260.1 - 7.2e-23 80.5 0.2 1.2e-22 79.8 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIB PF00382.19 KIK70261.1 - 6.4e-35 119.0 0.4 2e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KIK70261.1 - 3.3e-26 91.6 1.4 3.3e-26 91.6 1.4 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KIK70261.1 - 5.6e-08 32.2 3.1 1.4e-07 30.9 3.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KIK70261.1 - 0.00075 19.3 0.4 0.27 11.0 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF4145 PF13643.6 KIK70261.1 - 0.12 12.5 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Mrr_N PF14338.6 KIK70261.1 - 3.3 7.9 6.9 0.88 9.7 0.8 2.8 2 1 1 3 3 3 0 Mrr N-terminal domain AP3D1 PF06375.11 KIK70261.1 - 5.6 7.2 15.0 5.8 7.1 6.2 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 MFS_1 PF07690.16 KIK70263.1 - 5.9e-44 150.4 41.9 1.1e-43 149.5 41.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK70263.1 - 3.3e-15 55.9 34.7 6.1e-15 55.0 9.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter zf-C2H2_jaz PF12171.8 KIK70264.1 - 7.4e-15 54.8 40.7 0.0014 18.9 0.3 9.0 8 1 1 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK70264.1 - 1.3e-09 38.1 68.8 0.006 17.3 0.7 10.4 10 1 0 10 10 9 6 C2H2-type zinc finger zf-met PF12874.7 KIK70264.1 - 1.2e-06 28.7 41.8 0.0084 16.5 0.4 9.4 10 0 0 10 10 10 3 Zinc-finger of C2H2 type zf-C3HC4 PF00097.25 KIK70264.1 - 0.0003 20.6 17.6 0.0003 20.6 17.6 5.2 4 2 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70264.1 - 0.0018 18.5 17.2 0.0018 18.5 17.2 5.4 5 3 1 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK70264.1 - 0.002 18.0 17.8 0.002 18.0 17.8 5.5 6 2 1 7 7 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK70264.1 - 0.0026 17.6 13.9 0.0026 17.6 13.9 5.9 5 3 1 6 6 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK70264.1 - 0.0031 17.4 16.6 0.0031 17.4 16.6 5.7 3 2 2 5 5 2 1 zinc-RING finger domain Rad50_zn_hook PF04423.14 KIK70264.1 - 0.016 15.0 1.5 1.2 9.0 0.2 3.0 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 KIK70264.1 - 0.03 14.8 0.9 0.03 14.8 0.9 9.9 10 0 0 10 10 9 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK70264.1 - 0.053 13.9 0.3 0.053 13.9 0.3 6.0 3 2 3 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KIK70264.1 - 0.055 13.3 19.5 4.6 7.2 0.1 7.2 4 2 4 8 8 8 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 KIK70264.1 - 0.23 12.1 21.1 2.2 9.0 2.1 5.7 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF4336 PF14234.6 KIK70265.1 - 1e-09 38.1 0.0 0.0024 17.1 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) F-box-like PF12937.7 KIK70266.1 - 9.5e-06 25.4 0.1 3.7e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 F-box-like Hira PF07569.11 KIK70267.1 - 1.1e-54 185.6 0.0 2e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KIK70267.1 - 9.9e-29 99.0 21.0 2.8e-05 24.8 0.3 9.2 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70267.1 - 3.7e-14 52.8 2.0 0.039 14.3 0.1 6.6 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK70267.1 - 0.046 12.7 1.0 3.9 6.3 0.0 3.8 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_1 PF07690.16 KIK70268.1 - 1.2e-16 60.6 18.8 1.6e-16 60.2 18.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily 60KD_IMP PF02096.20 KIK70268.1 - 0.31 10.9 3.8 0.33 10.8 0.4 2.4 2 1 0 2 2 2 0 60Kd inner membrane protein SHMT PF00464.19 KIK70269.1 - 5.1e-172 572.0 0.0 5.9e-172 571.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KIK70269.1 - 0.00089 18.6 0.0 0.0066 15.8 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KIK70269.1 - 0.0013 18.0 0.0 0.0035 16.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIK70269.1 - 0.08 11.9 0.0 0.14 11.0 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V adh_short_C2 PF13561.6 KIK70271.1 - 8.6e-59 198.9 0.0 9.9e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70271.1 - 1.1e-45 155.5 0.0 1.5e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70271.1 - 6.2e-07 29.5 0.1 8.8e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KIK70272.1 - 4.7e-45 154.2 0.0 6.4e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KIK70274.1 - 6.1e-62 209.2 0.1 7.1e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70274.1 - 1.4e-48 165.0 0.0 1.7e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70274.1 - 2.3e-07 30.9 0.1 3.5e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 KIK70275.1 - 5.8e-29 101.1 31.3 8.7e-29 100.5 31.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.13 KIK70275.1 - 4.3 7.7 21.2 2.7 8.4 5.4 3.7 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) p450 PF00067.22 KIK70276.1 - 6.8e-55 186.6 0.0 7.8e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIK70277.1 - 8.5e-29 100.6 31.6 8.5e-29 100.6 31.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 KIK70278.1 - 3.2e-52 177.5 0.6 1e-51 175.8 0.1 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK70278.1 - 4.5e-42 144.5 0.1 7.5e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK70278.1 - 1.2e-17 63.8 0.0 2.4e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.18 KIK70278.1 - 5.1e-14 51.9 9.1 1.2e-13 50.8 9.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain F-box-like PF12937.7 KIK70279.1 - 9.4e-05 22.2 0.7 0.0012 18.7 0.7 2.6 1 1 0 1 1 1 1 F-box-like HNH_2 PF13391.6 KIK70280.1 - 7.3e-05 22.8 0.1 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Head_binding PF09008.10 KIK70280.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Head binding zf-MYND PF01753.18 KIK70282.1 - 1.2e-08 34.9 16.1 2.6e-08 33.8 16.1 1.6 1 0 0 1 1 1 1 MYND finger DUF4336 PF14234.6 KIK70283.1 - 1.5e-11 44.1 0.0 0.0076 15.5 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) PI-TkoII_IV PF18714.1 KIK70283.1 - 0.0004 19.9 0.1 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase II intein Domain IV GST_N PF02798.20 KIK70284.1 - 4.8e-16 58.9 0.0 1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK70284.1 - 2e-12 47.3 0.1 3.8e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK70284.1 - 2.3e-10 40.6 0.1 8.3e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK70284.1 - 4.2e-07 30.1 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK70284.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK70284.1 - 6.7e-05 23.6 0.0 0.00036 21.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KIK70284.1 - 0.011 16.0 0.0 0.28 11.5 0.0 2.4 2 1 0 2 2 2 0 Outer mitochondrial membrane transport complex protein EMP24_GP25L PF01105.24 KIK70285.1 - 2.6e-45 154.6 0.3 3e-45 154.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 KIK70285.1 - 0.046 14.2 0.3 0.081 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Dioxygenase_C PF00775.21 KIK70289.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase p450 PF00067.22 KIK70290.1 - 5.7e-65 219.8 0.0 6.8e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_6 PF13964.6 KIK70293.1 - 0.003 17.8 0.4 1.1 9.7 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Hanta_G1 PF01567.16 KIK70293.1 - 0.085 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Oxysterol_BP PF01237.18 KIK70294.1 - 2.2e-44 151.8 0.0 1.5e-27 96.4 0.0 2.4 2 1 0 2 2 2 2 Oxysterol-binding protein AcetylCoA_hydro PF02550.15 KIK70295.1 - 1.5e-42 145.8 0.0 2.5e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIK70295.1 - 1.3e-40 138.9 0.0 1.9e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 KIK70295.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 2 0 0 2 2 2 0 Citrate lyase, alpha subunit (CitF) Cupin_4 PF08007.12 KIK70296.1 - 0.0088 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Sulfotransfer_3 PF13469.6 KIK70298.1 - 8.4e-07 29.6 0.1 1.1e-05 25.9 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK70300.1 - 9.2e-07 29.5 0.0 6.1e-06 26.8 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 KIK70301.1 - 1.8e-08 35.1 0.0 2.2e-07 31.5 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase family F-box-like PF12937.7 KIK70303.1 - 0.065 13.1 7.8 0.46 10.4 7.8 2.3 1 1 0 1 1 1 0 F-box-like DMSP_lyase PF16867.5 KIK70305.1 - 0.0037 16.9 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase PIGA PF08288.12 KIK70306.1 - 8.6e-37 125.6 0.0 3e-36 123.9 0.1 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KIK70306.1 - 1.1e-25 90.6 1.8 2.4e-25 89.5 1.8 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIK70306.1 - 4.3e-24 85.0 0.0 7.3e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK70306.1 - 6.4e-22 78.4 0.0 1.9e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIK70306.1 - 1.8e-12 48.0 0.2 3.6e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KIK70306.1 - 0.0067 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KIK70306.1 - 0.0072 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mg_trans_NIPA PF05653.14 KIK70307.1 - 6.3e-83 278.3 11.3 7.4e-83 278.1 11.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIK70307.1 - 0.0099 16.1 3.1 0.0099 16.1 3.1 2.3 2 0 0 2 2 2 1 EamA-like transporter family DUF4265 PF14085.6 KIK70307.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) RVT_2 PF07727.14 KIK70312.1 - 0.00077 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPS PF01242.19 KIK70314.1 - 0.09 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Helitron_like_N PF14214.6 KIK70315.1 - 3.2e-18 66.6 0.3 3.7e-18 66.4 0.3 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4344 PF14247.6 KIK70315.1 - 0.015 15.0 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase Terminase_5 PF06056.12 KIK70317.1 - 0.098 12.6 0.1 3 7.8 0.0 2.7 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) Thaumatin PF00314.17 KIK70319.1 - 1e-06 28.5 8.1 0.00012 21.8 2.1 3.0 1 1 2 3 3 3 3 Thaumatin family CRAL_TRIO PF00650.20 KIK70320.1 - 5.4e-35 120.5 0.0 6.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK70320.1 - 5.7e-08 32.8 1.2 1.1e-07 31.9 1.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DCP1 PF06058.13 KIK70321.1 - 6.5e-24 84.1 0.0 7e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family Transp_cyt_pur PF02133.15 KIK70323.1 - 9.8e-110 367.3 34.9 1.1e-109 367.1 34.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2374 PF09574.10 KIK70323.1 - 0.0099 15.7 0.9 4.3 7.2 0.3 3.0 2 0 0 2 2 2 2 Protein of unknown function (Duf2374) Reprolysin_5 PF13688.6 KIK70326.1 - 7.2e-46 156.8 6.9 7.2e-46 156.8 6.9 2.8 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KIK70326.1 - 9.6e-45 152.9 4.3 9.6e-45 152.9 4.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KIK70326.1 - 5.2e-44 150.3 2.4 9.6e-44 149.5 2.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KIK70326.1 - 1.5e-17 64.2 26.0 1.5e-17 64.2 26.0 4.1 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KIK70326.1 - 7.5e-15 55.5 0.0 2.4e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KIK70326.1 - 4.8e-07 29.9 4.7 4.8e-07 29.9 4.7 2.7 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KIK70326.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KIK70326.1 - 0.0085 16.6 9.1 0.0085 16.6 9.1 3.8 1 1 3 4 4 4 2 ADAM cysteine-rich domain Peptidase_M66 PF10462.9 KIK70326.1 - 0.086 11.8 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 p450 PF00067.22 KIK70327.1 - 3.9e-72 243.5 0.0 5.3e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TraL PF07178.11 KIK70328.1 - 0.032 14.7 0.8 0.097 13.1 0.0 2.0 2 0 0 2 2 2 0 TraL protein stn_TNFRSF12A PF12191.8 KIK70328.1 - 0.086 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2207 PF09972.9 KIK70328.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Asp PF00026.23 KIK70329.1 - 3.2e-07 30.1 1.3 4.1e-07 29.7 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK70329.1 - 0.02 15.1 1.6 1.1 9.4 0.5 2.0 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal CLP_protease PF00574.23 KIK70330.1 - 1.3e-75 253.3 0.0 1.6e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease Brr6_like_C_C PF10104.9 KIK70332.1 - 2.4e-21 75.9 0.0 2.9e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain 4F5 PF04419.14 KIK70333.1 - 2.2e-08 34.8 11.4 2.2e-08 34.8 11.4 2.2 2 0 0 2 2 2 1 4F5 protein family DUF4778 PF16008.5 KIK70333.1 - 1 9.4 6.7 1.1 9.3 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TPR_1 PF00515.28 KIK70334.1 - 3.4e-58 191.2 28.1 7.5e-08 31.9 0.0 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIK70334.1 - 1e-53 175.1 21.0 2.1e-06 27.4 0.5 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 KIK70334.1 - 8.8e-45 147.2 13.1 0.00013 21.9 1.6 10.9 10 1 0 10 10 10 10 Tetratricopeptide repeat TPR_14 PF13428.6 KIK70334.1 - 3.2e-31 105.3 13.1 0.01 16.6 0.0 9.7 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 KIK70334.1 - 1.6e-30 105.4 14.6 1.5e-08 35.2 0.0 7.2 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK70334.1 - 9.5e-30 102.7 16.2 1.9e-05 24.9 0.0 8.3 4 3 3 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 KIK70334.1 - 3.3e-29 100.3 24.1 9.6e-07 28.4 0.4 10.3 7 2 3 10 10 10 7 TPR repeat TPR_19 PF14559.6 KIK70334.1 - 4.2e-27 94.4 11.9 2.3e-05 24.8 0.3 7.1 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK70334.1 - 7.7e-27 91.7 11.8 0.0026 18.0 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK70334.1 - 2.4e-25 86.7 14.9 0.021 14.8 0.0 9.8 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_6 PF13174.6 KIK70334.1 - 2.6e-25 87.3 15.7 0.014 16.0 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 KIK70334.1 - 1.6e-17 63.4 12.6 0.003 17.7 0.3 6.9 2 2 5 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK70334.1 - 9.3e-13 48.2 8.1 3.5e-05 24.0 1.6 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KIK70334.1 - 2.4e-11 43.4 6.5 0.0064 15.7 2.2 5.9 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_21 PF09976.9 KIK70334.1 - 2.6e-07 30.5 11.3 0.0097 15.6 0.3 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KIK70334.1 - 2.8e-07 30.3 0.5 0.00017 21.1 0.0 2.9 2 1 0 2 2 2 1 MalT-like TPR region SNAP PF14938.6 KIK70334.1 - 1.7e-06 27.7 10.2 0.031 13.7 0.2 5.2 1 1 3 5 5 5 2 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 KIK70334.1 - 1.1e-05 25.2 1.6 7 6.3 0.0 5.5 4 2 1 6 6 6 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 KIK70334.1 - 5.4e-05 23.1 21.5 0.79 9.8 1.2 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK70334.1 - 7.6e-05 22.4 17.2 0.18 11.8 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF2225 PF09986.9 KIK70334.1 - 0.00036 20.3 2.1 0.39 10.4 0.0 4.2 1 1 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 KIK70334.1 - 0.00099 18.2 1.1 0.88 8.5 0.1 2.7 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF2989 PF11207.8 KIK70334.1 - 0.0026 17.6 2.4 1.9 8.2 0.0 3.7 1 1 4 5 5 5 1 Protein of unknown function (DUF2989) TPR_20 PF14561.6 KIK70334.1 - 0.0074 16.6 5.6 0.12 12.7 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF4919 PF16266.5 KIK70334.1 - 0.014 15.4 0.2 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4919) Tcf25 PF04910.14 KIK70334.1 - 0.079 12.0 0.6 6 5.8 0.0 3.0 3 0 0 3 3 3 0 Transcriptional repressor TCF25 DUF627 PF04781.12 KIK70334.1 - 0.081 12.9 0.7 14 5.8 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Cohesin_load PF10345.9 KIK70334.1 - 0.084 11.3 1.2 16 3.8 0.2 3.3 2 1 2 4 4 4 0 Cohesin loading factor MIT PF04212.18 KIK70334.1 - 0.1 12.7 18.1 33 4.7 3.2 6.6 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 KIK70334.1 - 1.3 9.8 8.8 3.5 8.4 0.0 4.3 5 0 0 5 5 3 0 Sel1 repeat Erf4 PF10256.9 KIK70337.1 - 9.9e-28 96.6 0.1 1.4e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family bZIP_1 PF00170.21 KIK70338.1 - 3.5e-12 46.2 14.5 5.8e-12 45.5 14.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK70338.1 - 7.2e-05 22.8 14.2 7.2e-05 22.8 14.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 KIK70338.1 - 0.00021 21.1 3.8 0.00036 20.3 3.8 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DivIC PF04977.15 KIK70338.1 - 0.0063 16.2 5.3 0.0063 16.2 5.3 2.3 1 1 1 2 2 2 1 Septum formation initiator YabA PF06156.13 KIK70338.1 - 0.02 15.5 5.7 0.044 14.4 5.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA FAM163 PF15069.6 KIK70338.1 - 0.02 15.3 0.9 0.02 15.3 0.9 2.1 2 0 0 2 2 2 0 FAM163 family V_ATPase_I PF01496.19 KIK70338.1 - 0.033 12.1 9.9 0.047 11.6 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YqgF PF14639.6 KIK70338.1 - 0.12 12.2 1.1 0.22 11.3 1.1 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 XhlA PF10779.9 KIK70338.1 - 0.22 11.8 4.4 0.39 11.0 4.4 1.3 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.18 KIK70338.1 - 0.44 10.9 8.5 0.15 12.4 3.0 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family TSA PF03249.13 KIK70338.1 - 1.9 7.2 6.0 3 6.5 6.0 1.2 1 0 0 1 1 1 0 Type specific antigen APG6_N PF17675.1 KIK70338.1 - 3.5 8.2 16.5 6.3 7.3 16.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SNF2_N PF00176.23 KIK70339.1 - 1.7e-70 237.5 0.1 4.1e-70 236.3 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KIK70339.1 - 2.6e-20 72.3 0.3 7.7e-20 70.8 0.3 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KIK70339.1 - 4.9e-19 68.4 9.7 4.9e-19 68.4 9.7 2.9 2 0 0 2 2 2 1 HSA Helicase_C PF00271.31 KIK70339.1 - 5.1e-19 68.7 0.1 3.5e-18 66.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain QLQ PF08880.11 KIK70339.1 - 3.6e-14 52.2 0.4 8.4e-14 51.0 0.4 1.7 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 KIK70339.1 - 1.8e-09 38.1 0.3 1.8e-09 38.1 0.3 4.0 5 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KIK70339.1 - 1.3e-06 28.5 0.0 6.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Fer2 PF00111.27 KIK70340.1 - 4.5e-11 42.5 0.1 6.6e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-HC5HC2H_2 PF13832.6 KIK70341.1 - 0.011 15.9 0.5 0.016 15.4 0.5 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIK70341.1 - 0.093 13.0 2.6 0.17 12.2 2.6 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain HMG_box PF00505.19 KIK70343.1 - 8.4e-13 48.5 1.7 1.9e-12 47.4 1.7 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK70343.1 - 1.8e-05 25.2 0.1 3.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain PARP PF00644.20 KIK70344.1 - 8.2e-55 185.4 0.0 1.3e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KIK70344.1 - 3.6e-43 146.9 0.0 6.4e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KIK70344.1 - 3.9e-19 68.5 0.0 9.3e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 WGR domain MFAP1 PF06991.11 KIK70345.1 - 1.4e-66 224.4 27.0 1.4e-66 224.4 27.0 2.9 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing NAD_binding_8 PF13450.6 KIK70345.1 - 9.3e-13 48.2 0.0 2.6e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK70345.1 - 0.00053 19.7 0.9 0.0033 17.0 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK70345.1 - 0.032 14.2 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK70345.1 - 0.034 13.2 0.4 0.075 12.1 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KIK70345.1 - 0.09 12.0 0.2 0.25 10.5 0.2 1.7 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KIK70345.1 - 0.15 11.3 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK70345.1 - 0.19 11.0 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family zf-CCHC PF00098.23 KIK70345.1 - 0.22 11.7 1.6 0.46 10.7 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle UMP1 PF05348.11 KIK70346.1 - 1.3e-31 109.2 0.1 1.5e-31 109.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.28 KIK70347.1 - 2.1e-25 89.2 0.4 4.5e-25 88.1 0.4 1.6 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KIK70347.1 - 6e-18 65.2 0.0 1.1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIK70347.1 - 3e-05 23.8 0.4 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 LisH ProQ_C PF17516.2 KIK70347.1 - 0.04 13.3 0.0 1.6 8.2 0.0 2.7 3 0 0 3 3 3 0 ProQ C-terminal domain TPR_20 PF14561.6 KIK70347.1 - 0.062 13.6 0.4 0.29 11.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.20 KIK70348.1 - 6.4e-22 77.9 0.0 7.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis BAR PF03114.18 KIK70350.1 - 1.8e-44 152.2 1.4 2.6e-44 151.6 1.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIK70350.1 - 8.7e-15 54.1 0.1 1.6e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK70350.1 - 7.6e-14 51.3 0.1 1.2e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK70350.1 - 7.7e-09 35.1 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KIK70350.1 - 0.0084 15.7 3.7 3.9 7.0 2.2 3.1 2 1 1 3 3 3 3 Vps5 C terminal like Totivirus_coat PF05518.11 KIK70350.1 - 4.6 5.2 8.4 6.4 4.7 8.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein SBDS_C PF09377.10 KIK70351.1 - 3.2e-37 127.1 0.1 6.5e-37 126.1 0.1 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KIK70351.1 - 3.5e-34 116.7 1.4 6.6e-34 115.9 1.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myc_N PF01056.18 KIK70351.1 - 0.042 13.8 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Glycos_transf_1 PF00534.20 KIK70352.1 - 4.2e-10 39.4 0.0 6.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK70352.1 - 4.3e-10 40.1 0.0 7.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIK70352.1 - 1.2e-06 29.0 0.0 2.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIK70352.1 - 1.5e-05 25.1 0.1 3.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIK70352.1 - 0.0002 21.7 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SIMPL PF04402.14 KIK70353.1 - 0.0021 18.5 4.4 0.0038 17.7 4.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Exonuc_VII_L PF02601.15 KIK70353.1 - 0.028 14.0 2.1 0.038 13.6 2.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Striatin PF08232.12 KIK70353.1 - 0.052 14.1 0.6 0.1 13.2 0.6 1.5 1 0 0 1 1 1 0 Striatin family Med29 PF11568.8 KIK70353.1 - 0.052 13.8 0.3 0.088 13.0 0.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 Med2 PF11214.8 KIK70353.1 - 0.15 12.2 0.3 0.28 11.4 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 GCP_N_terminal PF17681.1 KIK70353.1 - 0.17 11.5 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Med3 PF11593.8 KIK70353.1 - 1.8 7.7 11.1 0.046 12.9 4.5 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Copper-fist PF00649.18 KIK70354.1 - 2.9e-21 74.7 0.6 2.9e-21 74.7 0.6 2.9 3 0 0 3 3 3 1 Copper fist DNA binding domain UQ_con PF00179.26 KIK70355.1 - 5e-29 100.7 0.1 6.1e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK70355.1 - 3e-05 23.7 0.0 0.016 14.9 0.1 2.1 1 1 1 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 KIK70355.1 - 0.0094 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 KIK70355.1 - 0.0098 15.5 0.0 0.031 13.9 0.0 1.6 1 1 0 2 2 2 1 Ubiquitin-fold modifier-conjugating enzyme 1 Porphobil_deam PF01379.20 KIK70356.1 - 1.7e-69 233.5 0.0 2.3e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KIK70356.1 - 2.8e-18 66.0 0.3 5.3e-18 65.2 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Nfu_N PF08712.11 KIK70357.1 - 5e-30 103.4 0.0 2.5e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KIK70357.1 - 7.2e-27 93.3 0.1 1.2e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain DUF4745 PF15923.5 KIK70357.1 - 0.084 12.8 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Atg14 PF10186.9 KIK70358.1 - 2.7e-16 59.6 0.0 8e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KIK70358.1 - 2.1e-07 30.2 2.1 0.00048 19.1 0.1 3.5 3 1 0 3 3 3 2 Vacuolar protein sorting 38 CENP-H PF05837.12 KIK70358.1 - 0.017 15.5 4.6 0.045 14.2 4.6 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 KIK70358.1 - 0.33 10.2 0.5 0.49 9.6 0.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DASH_Spc34 PF08657.10 KIK70358.1 - 0.33 10.7 10.0 0.022 14.6 3.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF724 PF05266.14 KIK70358.1 - 0.56 10.0 4.4 1.3 8.8 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 KIK70358.1 - 0.65 10.7 2.3 1.5 9.5 2.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA PUF PF00806.19 KIK70359.1 - 3.5e-58 190.1 11.3 2.5e-08 33.1 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_S14 PF00253.21 KIK70360.1 - 5.3e-14 51.7 3.6 5.7e-14 51.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e p450 PF00067.22 KIK70361.1 - 2.2e-61 208.0 0.0 4.4e-61 207.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SprT-like PF10263.9 KIK70362.1 - 3.7e-24 84.8 0.1 7.8e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 SprT-like family 2OG-FeII_Oxy_3 PF13640.6 KIK70363.1 - 8.9e-08 32.9 0.0 2.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 KIK70365.1 - 1.5e-10 41.0 16.4 2.9e-10 40.0 16.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C2H2_3 PF13878.6 KIK70365.1 - 0.83 9.5 3.4 1.9 8.4 3.4 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-HIT PF04438.16 KIK70365.1 - 0.98 9.4 10.4 13 5.8 10.4 2.3 1 1 0 1 1 1 0 HIT zinc finger EAV_GP5 PF15981.5 KIK70365.1 - 2.8 8.4 4.4 4.3 7.8 3.4 1.7 1 1 1 2 2 2 0 Envelope glycoprotein GP 5 of equine arteritis virus zf-Mss51 PF13824.6 KIK70365.1 - 6.4 7.0 7.7 19 5.4 7.7 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_79C PF16862.5 KIK70366.1 - 4.2e-06 27.6 0.1 2e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain WD40 PF00400.32 KIK70369.1 - 7.1e-32 109.0 8.2 1.1e-06 29.2 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KIK70369.1 - 4e-08 32.4 1.2 0.0023 16.7 0.0 4.0 4 1 1 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK70369.1 - 0.0024 18.1 0.0 12 6.3 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CTNNBL PF08216.11 KIK70369.1 - 0.23 11.7 1.8 0.44 10.7 1.8 1.4 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear DivIC PF04977.15 KIK70369.1 - 0.8 9.5 3.7 1.7 8.4 3.7 1.6 1 0 0 1 1 1 0 Septum formation initiator BC10 PF06726.12 KIK70370.1 - 4.6e-09 36.4 13.9 9.5e-09 35.4 13.7 1.7 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 DUF4131 PF13567.6 KIK70370.1 - 1.1 8.9 3.1 1.9 8.1 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) CS PF04969.16 KIK70371.1 - 5.7e-05 24.1 0.2 0.0001 23.2 0.0 1.5 2 0 0 2 2 2 1 CS domain Forkhead_N PF08430.12 KIK70371.1 - 0.39 11.3 17.2 0.61 10.7 17.2 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.11 KIK70371.1 - 2 6.4 10.0 2.6 6.0 10.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CBM_19 PF03427.13 KIK70372.1 - 4.5e-05 23.3 5.0 4.5e-05 23.3 5.0 3.2 2 1 0 2 2 2 1 Carbohydrate binding domain (family 19) HAD_2 PF13419.6 KIK70373.1 - 2e-20 73.6 0.0 2.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK70373.1 - 1.1e-08 35.7 0.0 1.9e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK70373.1 - 7.6e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIK70373.1 - 0.028 14.8 0.0 0.045 14.1 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIK70373.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Thg1 PF04446.12 KIK70375.1 - 6.8e-50 168.3 0.0 1e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KIK70375.1 - 1.3e-47 160.9 0.1 1.8e-47 160.5 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain UCH PF00443.29 KIK70376.1 - 6e-48 163.6 0.5 7.7e-48 163.2 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK70376.1 - 1.8e-18 67.2 9.3 2.8e-17 63.3 9.3 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIK70376.1 - 5.2e-12 45.9 8.5 5.2e-12 45.9 8.5 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein GHMP_kinases_N PF00288.26 KIK70377.1 - 5.3e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK70377.1 - 0.00047 20.5 0.0 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal AAA_6 PF12774.7 KIK70378.1 - 2.2e-126 421.3 0.0 1.4e-125 418.6 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KIK70378.1 - 8.4e-116 387.3 6.3 8.4e-116 387.3 6.3 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KIK70378.1 - 4.3e-73 245.1 0.6 4.3e-73 245.1 0.6 3.5 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KIK70378.1 - 3e-68 230.0 0.0 1.6e-67 227.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KIK70378.1 - 9e-50 169.6 0.0 3e-49 167.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KIK70378.1 - 5.4e-44 149.9 0.0 2e-36 125.2 0.0 5.0 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 KIK70378.1 - 1e-38 133.3 6.1 1e-38 133.3 6.1 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KIK70378.1 - 7.6e-37 126.7 0.0 1.6e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KIK70378.1 - 1.5e-29 102.7 0.0 4.2e-13 49.5 0.0 6.7 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KIK70378.1 - 3.8e-29 101.2 0.0 3.5e-28 98.1 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KIK70378.1 - 1.1e-16 61.1 0.1 2.7e-15 56.6 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KIK70378.1 - 1e-13 51.8 0.0 0.0012 19.3 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK70378.1 - 1.4e-13 51.3 0.0 0.0061 16.8 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KIK70378.1 - 1.2e-11 45.0 1.9 0.21 11.7 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 KIK70378.1 - 6e-10 39.8 0.1 0.61 10.5 0.0 6.9 6 0 0 6 6 5 2 AAA ATPase domain AAA_18 PF13238.6 KIK70378.1 - 3.2e-08 34.2 1.2 0.13 12.8 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.6 KIK70378.1 - 1.8e-06 28.1 0.0 2.1 8.4 0.0 5.7 5 0 0 5 5 5 1 AAA domain Mg_chelatase PF01078.21 KIK70378.1 - 1.3e-05 24.7 0.5 0.65 9.3 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KIK70378.1 - 1.5e-05 24.2 0.0 0.014 14.5 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIK70378.1 - 8.5e-05 22.0 0.0 0.31 10.4 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.6 KIK70378.1 - 8.7e-05 22.2 0.1 0.74 9.6 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KIK70378.1 - 0.00016 21.4 0.3 0.77 9.5 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_tran PF00005.27 KIK70378.1 - 0.00019 21.9 0.1 12 6.4 0.0 4.8 4 0 0 4 4 3 0 ABC transporter AAA_30 PF13604.6 KIK70378.1 - 0.0002 21.2 0.1 26 4.5 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_lid_1 PF17857.1 KIK70378.1 - 0.00023 21.3 1.1 0.0008 19.6 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain AAA_24 PF13479.6 KIK70378.1 - 0.0011 18.7 0.5 23 4.7 0.0 4.8 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 KIK70378.1 - 0.0012 19.2 3.6 0.31 11.4 0.0 4.9 5 0 0 5 5 5 1 AAA domain LOH1CR12 PF10158.9 KIK70378.1 - 0.0016 18.4 11.3 0.19 11.7 0.4 4.0 3 0 0 3 3 2 2 Tumour suppressor protein Rad17 PF03215.15 KIK70378.1 - 0.0017 18.3 0.4 24 4.8 0.0 4.7 5 0 0 5 5 5 0 Rad17 P-loop domain RNA_helicase PF00910.22 KIK70378.1 - 0.0025 18.2 0.0 9.2 6.7 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.6 KIK70378.1 - 0.011 15.3 0.0 0.66 9.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KIK70378.1 - 0.017 14.9 0.0 8.6 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 KIK70378.1 - 0.091 12.5 0.1 3 7.6 0.0 3.1 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 KIK70378.1 - 0.16 11.8 1.8 0.57 10.0 0.7 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase ERM PF00769.19 KIK70378.1 - 3.1 7.5 31.0 1.3 8.8 11.5 2.9 3 0 0 3 3 2 0 Ezrin/radixin/moesin family NACHT PF05729.12 KIK70378.1 - 3.8 7.4 5.9 39 4.1 0.1 4.5 5 0 0 5 5 3 0 NACHT domain Phage_GP20 PF06810.11 KIK70378.1 - 7.1 6.4 23.4 3.9 7.3 7.7 4.4 4 0 0 4 4 4 0 Phage minor structural protein GP20 LSM PF01423.22 KIK70379.1 - 4.9e-14 51.8 0.2 6.9e-14 51.3 0.2 1.3 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK70379.1 - 0.0011 18.5 0.1 0.002 17.7 0.1 1.5 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 KIK70379.1 - 0.096 12.6 0.1 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 PhnA domain Pex2_Pex12 PF04757.14 KIK70380.1 - 3.7e-20 72.5 4.0 6.6e-20 71.7 4.0 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIK70380.1 - 4e-09 36.2 6.9 5.6e-09 35.7 6.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK70380.1 - 5e-08 32.7 9.5 7.6e-08 32.1 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70380.1 - 3.1e-07 30.6 12.0 4.7e-07 30.0 12.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK70380.1 - 3.3e-07 30.0 9.9 4.9e-07 29.5 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK70380.1 - 8.1e-07 28.8 7.3 1.2e-06 28.2 7.3 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK70380.1 - 7.2e-06 25.9 9.3 1.2e-05 25.2 9.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK70380.1 - 5.4e-05 23.1 8.2 0.0001 22.2 8.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIK70380.1 - 6.9e-05 23.1 7.8 0.00013 22.2 7.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KIK70380.1 - 0.0023 18.1 10.0 0.0042 17.2 10.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KIK70380.1 - 0.071 13.2 2.9 0.12 12.4 2.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KIK70380.1 - 0.076 13.2 6.0 0.14 12.3 6.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KIK70380.1 - 0.57 10.1 5.7 1 9.2 5.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KIK70380.1 - 1.8 8.4 9.6 3.8 7.4 9.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KIK70380.1 - 8.3 6.7 10.4 20 5.5 10.4 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Romo1 PF10247.9 KIK70381.1 - 1.6e-19 70.0 7.0 2.4e-19 69.5 7.0 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF3512 PF12024.8 KIK70382.1 - 0.14 11.6 0.7 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.16 KIK70383.1 - 3.8e-09 36.3 0.0 5.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_pol_Rpb4 PF03874.16 KIK70385.1 - 1.8e-20 73.5 0.2 2.8e-20 72.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ashwin PF15323.6 KIK70386.1 - 0.5 10.4 9.2 0.89 9.5 9.2 1.4 1 0 0 1 1 1 0 Developmental protein RGCC PF15151.6 KIK70386.1 - 1.5 9.0 8.2 3.6 7.8 8.2 1.6 1 0 0 1 1 1 0 Response gene to complement 32 protein family MFS_1 PF07690.16 KIK70387.1 - 1.4e-41 142.6 53.0 4.6e-26 91.6 20.9 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK70387.1 - 2.6e-10 39.8 9.1 2.6e-10 39.8 9.1 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK70387.1 - 2.1e-09 36.7 24.6 4.6e-05 22.4 1.8 3.3 2 1 1 3 3 3 3 MFS_1 like family OATP PF03137.20 KIK70387.1 - 0.00046 18.6 2.0 0.00046 18.6 2.0 3.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KIK70387.1 - 0.18 11.1 21.6 0.077 12.3 7.0 2.7 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB Deltameth_res PF16020.5 KIK70387.1 - 2.3 8.1 4.4 1.7 8.6 0.0 3.2 4 0 0 4 4 4 0 Deltamethrin resistance Fapy_DNA_glyco PF01149.24 KIK70388.1 - 2.6e-25 89.3 1.3 7e-25 87.9 0.1 2.1 3 0 0 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KIK70388.1 - 2e-21 75.8 0.0 3.5e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KIK70388.1 - 0.0035 16.2 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KIK70388.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Utp12 PF04003.12 KIK70389.1 - 4.5e-25 88.0 0.0 8.7e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KIK70389.1 - 9.6e-05 23.1 3.9 1.2 10.2 1.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70389.1 - 0.028 14.7 0.4 9 6.7 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pesticin PF16754.5 KIK70389.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term Pkinase PF00069.25 KIK70390.1 - 1.9e-76 256.9 0.0 2.6e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70390.1 - 8.5e-37 126.8 0.0 1.8e-36 125.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK70390.1 - 5.5e-05 22.3 0.1 0.0002 20.5 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK70390.1 - 0.00053 19.4 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK70390.1 - 0.026 14.5 0.4 0.057 13.3 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK70390.1 - 0.038 13.3 0.5 0.11 11.9 0.5 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3754 PF12576.8 KIK70390.1 - 0.051 13.5 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) DUF1381 PF07129.11 KIK70390.1 - 0.095 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) MRP-L27 PF09809.9 KIK70391.1 - 3.5e-08 33.3 0.2 4.4e-08 33.0 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HTH_18 PF12833.7 KIK70391.1 - 0.08 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HATPase_c PF02518.26 KIK70394.1 - 3e-28 98.6 0.4 9.7e-28 96.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK70394.1 - 1.3e-16 60.7 0.0 4.3e-16 59.1 0.0 2.0 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.25 KIK70394.1 - 3.3e-14 52.7 0.0 1.2e-13 50.9 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KIK70394.1 - 1.9e-13 51.1 1.8 3.6e-12 47.0 0.2 3.2 3 0 0 3 3 2 1 AAA ATPase domain GAF_2 PF13185.6 KIK70394.1 - 6.6e-11 42.7 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KIK70394.1 - 1.7e-09 38.4 0.1 4.5e-08 33.8 0.0 2.9 3 0 0 3 3 2 1 GAF domain Pkinase PF00069.25 KIK70394.1 - 4.8e-09 36.0 0.0 8.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70394.1 - 1.9e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3369 PF11849.8 KIK70394.1 - 0.0023 18.2 1.0 0.36 11.0 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3369) HATPase_c_3 PF13589.6 KIK70394.1 - 0.0052 16.6 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_5 PF07728.14 KIK70394.1 - 0.0057 16.7 0.3 4.3 7.3 0.1 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK70394.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 KIK70394.1 - 0.029 14.6 3.4 0.11 12.8 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 KIK70394.1 - 0.05 13.9 0.3 3 8.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 KIK70394.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SpvB PF03534.13 KIK70394.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein RuvB_N PF05496.12 KIK70394.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIK70394.1 - 1.6 8.9 5.4 17 5.5 0.5 3.5 4 0 0 4 4 4 0 AAA domain DEAD PF00270.29 KIK70395.1 - 6.2e-37 127.1 0.1 1e-36 126.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK70395.1 - 6.6e-28 97.3 0.1 4.9e-25 88.0 0.0 2.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK70395.1 - 3.6e-09 36.8 0.0 7.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NgoMIV_restric PF09015.10 KIK70395.1 - 0.097 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 NgoMIV restriction enzyme RRM_1 PF00076.22 KIK70396.1 - 4.9e-44 148.0 0.0 2.5e-15 56.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK70396.1 - 0.004 16.7 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KIK70396.1 - 0.0072 16.4 0.1 0.21 11.7 0.0 3.0 3 1 0 3 3 3 1 Limkain b1 DUF3343 PF11823.8 KIK70396.1 - 0.012 15.1 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) RRM_3 PF08777.11 KIK70396.1 - 0.021 14.8 0.0 9.6 6.3 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif VIT PF08487.10 KIK70397.1 - 5.2e-28 97.5 0.0 9.4e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK70397.1 - 2.6e-22 79.4 0.0 6.4e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK70397.1 - 8.8e-13 48.9 0.0 1.9e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK70397.1 - 2e-07 31.6 0.2 5.1e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KIK70397.1 - 1.8e-05 24.5 0.0 5.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KIK70397.1 - 0.00018 21.0 1.0 0.00038 19.9 0.6 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KIK70397.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus Mito_carr PF00153.27 KIK70398.1 - 5.5e-52 173.7 2.9 2.5e-18 65.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.14 KIK70399.1 - 3.3e-15 56.2 3.6 5.3e-15 55.5 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KIK70399.1 - 0.037 14.3 7.6 0.037 14.3 3.6 2.7 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) DEAD PF00270.29 KIK70400.1 - 4.1e-38 130.9 0.0 7.9e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK70400.1 - 5.8e-25 87.8 0.0 2e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK70400.1 - 1.4e-06 28.4 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PolyA_pol PF01743.20 KIK70401.1 - 2e-26 92.9 0.0 3.5e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KIK70401.1 - 7.3e-06 25.6 0.0 2.7e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KIK70401.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Nop PF01798.18 KIK70402.1 - 4.1e-71 239.1 0.0 6.1e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KIK70402.1 - 7.2e-36 123.7 5.1 1.3e-35 123.0 5.1 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Pro-kuma_activ PF09286.11 KIK70403.1 - 1.8e-48 164.4 0.1 3.3e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK70403.1 - 0.00056 19.3 0.6 0.0011 18.3 0.6 1.4 1 0 0 1 1 1 1 Subtilase family EKLF_TAD2 PF16833.5 KIK70403.1 - 0.28 11.3 1.3 0.98 9.5 1.3 1.9 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 2 Glyco_hydro_7 PF00840.20 KIK70404.1 - 3.9e-202 671.7 10.4 4.6e-202 671.5 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KIK70404.1 - 6e-12 45.3 3.7 6e-12 45.3 3.7 5.2 4 1 0 4 4 4 1 Fungal cellulose binding domain Trefoil PF00088.18 KIK70404.1 - 0.41 10.6 7.3 7.4 6.5 1.5 3.1 2 0 0 2 2 2 0 Trefoil (P-type) domain Peroxidase_ext PF11895.8 KIK70405.1 - 1.6e-30 104.8 1.8 1.6e-30 104.8 1.8 2.2 2 0 0 2 2 2 1 Fungal peroxidase extension region peroxidase PF00141.23 KIK70405.1 - 5.4e-28 98.3 0.0 7.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Arm PF00514.23 KIK70406.1 - 1.3e-70 231.5 29.5 4.8e-13 48.6 0.1 11.7 11 1 1 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK70406.1 - 7.9e-21 74.2 11.5 0.00092 19.7 0.3 8.1 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 KIK70406.1 - 1.2e-18 67.2 6.0 0.008 16.5 0.1 7.2 4 3 2 7 7 7 5 HEAT repeats HEAT PF02985.22 KIK70406.1 - 6.7e-16 57.0 13.4 0.18 12.1 0.0 9.5 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.13 KIK70406.1 - 5.7e-11 42.4 9.5 4.1e-08 33.0 1.2 2.6 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KIK70406.1 - 1.6e-10 40.2 10.1 3e-08 32.7 0.1 2.7 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 KIK70406.1 - 8.3e-10 37.5 1.3 1.2e-09 36.9 1.3 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KIK70406.1 - 8e-09 35.2 6.0 0.0011 18.4 2.5 4.3 2 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 KIK70406.1 - 7.3e-07 29.4 4.7 0.014 15.5 0.1 5.0 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KIK70406.1 - 0.00042 20.3 5.5 1.4 8.8 0.0 3.9 1 1 1 3 3 3 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KIK70406.1 - 0.0033 17.5 3.3 34 4.6 0.1 4.8 1 1 5 6 6 6 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 KIK70406.1 - 0.045 14.4 0.1 10 6.8 0.0 3.3 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KIK70406.1 - 0.13 13.0 13.4 56 4.8 0.3 7.4 8 1 0 8 8 7 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 KIK70406.1 - 0.17 10.3 4.3 3.8 5.9 0.9 2.5 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.9 KIK70406.1 - 0.23 11.5 4.0 0.46 10.5 0.1 3.2 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KIK70406.1 - 3.4 8.1 4.3 47 4.5 0.1 3.9 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glyco_hydro_16 PF00722.21 KIK70407.1 - 2.3e-06 27.2 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Spc110_C PF18520.1 KIK70409.1 - 0.33 10.6 4.9 1.9 8.2 0.7 2.5 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain GYF PF02213.16 KIK70410.1 - 1.1e-15 57.0 1.0 2.7e-15 55.8 1.0 1.7 1 0 0 1 1 1 1 GYF domain Acatn PF13000.7 KIK70411.1 - 2.1e-147 492.0 26.2 5e-69 233.3 15.3 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.22 KIK70412.1 - 9.8e-64 215.8 0.0 1.2e-63 215.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK70413.1 - 1.2e-53 182.5 0.0 1.6e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 KIK70414.1 - 2.9e-07 29.8 0.1 5.7e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KIK70414.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1206 PF06724.11 KIK70414.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Mid2 PF04478.12 KIK70414.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 KIK70414.1 - 0.091 12.7 0.4 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Spc7 PF08317.11 KIK70415.1 - 3.5e-92 308.6 13.8 5e-92 308.1 13.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KIK70415.1 - 1.1e-06 28.7 0.1 2.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Spc7_C2 DUF5030 PF16433.5 KIK70415.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) DUF3921 PF13060.6 KIK70415.1 - 0.22 11.5 1.0 0.5 10.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) MscS_porin PF12795.7 KIK70415.1 - 0.3 10.6 20.9 0.039 13.5 16.1 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 KIK70415.1 - 1.4 8.3 7.7 2.5 7.4 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KIK70415.1 - 5.4 7.4 19.6 2 8.8 10.2 2.4 1 1 1 2 2 2 0 Fez1 RbsD_FucU PF05025.13 KIK70415.1 - 9.1 6.7 6.0 18 5.7 2.1 2.4 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF641 PF04859.12 KIK70415.1 - 9.9 6.5 10.1 7.8 6.9 6.0 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Apolipoprotein PF01442.18 KIK70416.1 - 0.001 19.0 3.0 0.0013 18.6 3.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KIK70416.1 - 0.041 14.5 3.5 0.08 13.6 3.5 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) tRNA-synt_1e PF01406.19 KIK70416.1 - 0.089 12.1 0.3 0.099 12.0 0.3 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain YtxH PF12732.7 KIK70416.1 - 0.27 11.8 11.5 20 5.8 11.5 2.2 1 1 0 1 1 1 0 YtxH-like protein STAG PF08514.11 KIK70416.1 - 2.3 8.2 4.9 1.2 9.1 0.1 2.0 1 1 1 2 2 2 0 STAG domain HMG_box PF00505.19 KIK70417.1 - 7.3e-07 29.5 0.1 1.6e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CAP_N PF01213.19 KIK70417.1 - 1.6 8.2 7.3 3.4 7.1 7.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEAD PF00270.29 KIK70418.1 - 4.1e-43 147.2 0.8 4.1e-43 147.2 0.8 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK70418.1 - 3.8e-32 110.9 0.3 7.2e-31 106.8 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KIK70418.1 - 0.00035 20.9 0.4 0.006 16.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KIK70418.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KIK70418.1 - 0.056 12.2 0.6 1.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ABC_tran PF00005.27 KIK70420.1 - 8.5e-40 136.4 0.0 4.6e-25 88.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK70420.1 - 6e-39 134.3 21.1 1.5e-24 87.2 12.0 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK70420.1 - 6.9e-12 45.3 0.6 0.0007 19.1 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK70420.1 - 5.2e-06 27.0 0.1 0.032 14.6 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK70420.1 - 2.1e-05 24.5 8.4 0.017 15.0 0.3 4.4 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KIK70420.1 - 2.2e-05 24.1 0.1 0.018 14.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KIK70420.1 - 2.7e-05 24.5 0.1 0.15 12.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIK70420.1 - 6.2e-05 23.6 0.4 0.0022 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIK70420.1 - 0.0004 19.6 0.0 0.37 9.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KIK70420.1 - 0.00055 19.9 0.1 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KIK70420.1 - 0.00065 19.8 0.2 2 8.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK70420.1 - 0.00087 19.0 0.9 0.83 9.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK70420.1 - 0.0034 16.9 0.2 3.2 7.2 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK70420.1 - 0.0034 17.1 0.1 2.4 7.8 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Dynamin_N PF00350.23 KIK70420.1 - 0.011 15.8 3.6 0.16 12.0 0.0 2.8 3 0 0 3 3 2 0 Dynamin family Roc PF08477.13 KIK70420.1 - 0.033 14.4 1.1 12 6.1 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KIK70420.1 - 0.042 14.3 0.8 5.9 7.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KIK70420.1 - 0.053 12.9 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KIK70420.1 - 0.054 13.6 1.5 0.73 9.9 0.6 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 KIK70420.1 - 0.099 12.9 0.4 8.4 6.7 0.0 3.7 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 KIK70420.1 - 0.15 10.8 0.1 0.57 8.9 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 KIK70420.1 - 0.17 11.6 1.2 2.7 7.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 KIK70420.1 - 0.18 11.8 0.0 9.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KIK70420.1 - 0.25 11.4 0.9 26 4.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KIK70420.1 - 0.59 9.7 2.7 0.81 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0182 PF03699.13 KIK70420.1 - 6 4.9 8.8 13 3.8 8.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Kinesin PF00225.23 KIK70421.1 - 6.4e-85 285.0 1.0 1.9e-84 283.5 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIK70421.1 - 3.9e-16 59.3 0.2 1.3e-13 51.1 0.0 3.5 4 0 0 4 4 4 1 Microtubule binding GP24_25 PF17388.2 KIK70421.1 - 0.13 12.2 1.3 7.5 6.5 0.8 3.0 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 ATP11 PF06644.11 KIK70422.1 - 1.4e-82 277.5 0.0 1.6e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein STG PF15809.5 KIK70422.1 - 0.011 15.8 0.6 0.017 15.2 0.6 1.3 1 0 0 1 1 1 0 Simian taste bud-specific gene product family DUF5333 PF17267.2 KIK70422.1 - 0.068 13.4 0.7 0.11 12.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5333) DUF883 PF05957.13 KIK70422.1 - 0.076 13.6 7.0 0.13 12.9 7.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PI3K_C2 PF00792.24 KIK70422.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 DUF4407 PF14362.6 KIK70422.1 - 1.8 7.8 5.5 2.6 7.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DIE2_ALG10 PF04922.12 KIK70426.1 - 1.2e-125 419.9 11.4 1.5e-125 419.6 11.4 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family DUF3328 PF11807.8 KIK70428.1 - 6.8e-52 176.4 1.8 8.3e-52 176.1 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Claudin_2 PF13903.6 KIK70429.1 - 1.1 8.9 6.8 1.8 8.3 3.7 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TauD PF02668.16 KIK70430.1 - 1.3e-54 185.8 0.4 1.8e-54 185.4 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OPT PF03169.15 KIK70431.1 - 2.4e-181 604.5 51.1 2.8e-181 604.3 51.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Oleosin PF01277.17 KIK70431.1 - 0.076 12.8 6.2 0.44 10.3 0.0 3.3 2 0 0 2 2 2 0 Oleosin DUF2418 PF10332.9 KIK70431.1 - 0.36 11.4 3.5 0.68 10.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) Prp19 PF08606.11 KIK70432.1 - 1.7e-32 111.2 3.1 3.4e-32 110.3 3.1 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KIK70432.1 - 6.2e-12 45.8 3.0 0.19 12.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70432.1 - 1.5e-10 41.2 0.0 2e-05 24.8 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIK70432.1 - 8.7e-05 21.0 0.0 0.00034 19.1 0.0 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz U-box PF04564.15 KIK70432.1 - 0.00013 22.0 0.0 0.00036 20.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KIK70432.1 - 0.00029 20.6 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cep57_MT_bd PF06657.13 KIK70432.1 - 0.045 14.2 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4073 PF13285.6 KIK70432.1 - 0.087 12.5 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) Glyco_hydro_61 PF03443.14 KIK70433.1 - 1.5e-65 221.0 0.1 1.7e-65 220.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SGTA_dimer PF16546.5 KIK70434.1 - 2.4e-27 94.5 0.3 6.2e-27 93.2 0.3 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KIK70434.1 - 3.3e-18 64.6 7.4 3.3e-07 29.8 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK70434.1 - 1.7e-16 59.6 7.0 6.8e-11 41.7 0.6 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 KIK70434.1 - 1.9e-14 52.5 8.2 3.5e-06 26.7 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK70434.1 - 1.3e-11 43.7 6.8 0.0026 17.9 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK70434.1 - 1.4e-08 35.2 8.1 3.3e-06 27.6 2.9 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK70434.1 - 1.6e-06 28.3 4.6 0.011 16.0 1.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK70434.1 - 2.6e-06 27.4 4.3 0.28 11.6 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK70434.1 - 5.1e-06 26.9 6.9 0.008 16.9 0.1 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK70434.1 - 6.2e-06 25.9 1.5 0.0085 16.1 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK70434.1 - 0.0011 19.0 1.1 0.028 14.6 0.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 KIK70434.1 - 0.0023 17.8 14.8 0.032 14.2 7.2 3.6 3 1 1 4 4 4 2 STI1 domain TPR_10 PF13374.6 KIK70434.1 - 0.0044 16.9 5.3 6.4 6.8 0.5 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK70434.1 - 0.0052 17.3 6.2 1 9.9 0.2 3.2 1 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK70434.1 - 0.057 13.7 2.0 3 8.1 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KIK70434.1 - 0.11 12.6 4.4 1.1 9.4 0.5 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KIK70434.1 - 0.27 11.6 1.8 3.2 8.2 0.4 2.4 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Myb_DNA-binding PF00249.31 KIK70435.1 - 2.6e-32 110.7 2.3 1.1e-11 44.8 0.2 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK70435.1 - 1.1e-29 102.4 2.0 7.4e-12 45.3 0.0 3.8 2 1 2 4 4 4 3 Myb-like DNA-binding domain zf-C2H2_aberr PF17017.5 KIK70435.1 - 0.00065 19.9 0.6 0.027 14.6 0.1 2.2 2 0 0 2 2 2 1 Aberrant zinc-finger SLIDE PF09111.10 KIK70435.1 - 0.0037 17.3 0.0 18 5.4 0.0 3.3 2 1 1 3 3 3 2 SLIDE zf-C2H2_4 PF13894.6 KIK70435.1 - 0.24 12.3 11.8 8.5 7.5 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK70435.1 - 3 8.5 15.3 0.59 10.7 1.9 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Myb_DNA-bind_4 PF13837.6 KIK70435.1 - 5.9 7.3 7.9 6.2 7.3 1.4 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Cation_efflux PF01545.21 KIK70436.1 - 8.8e-18 64.7 10.9 1.1e-17 64.5 10.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK70436.1 - 1.5e-11 44.3 1.0 1.5e-10 41.0 0.0 2.5 3 0 0 3 3 3 1 Dimerisation domain of Zinc Transporter PcfJ PF14284.6 KIK70436.1 - 0.17 11.8 0.2 0.3 11.0 0.2 1.4 1 0 0 1 1 1 0 PcfJ-like protein NAD_binding_8 PF13450.6 KIK70438.1 - 3.5e-08 33.5 0.0 7.8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK70438.1 - 7e-06 26.1 0.0 0.00095 19.2 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FMO-like PF00743.19 KIK70438.1 - 7.4e-05 21.4 1.3 0.02 13.3 0.8 3.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK70438.1 - 0.00028 20.2 0.0 0.041 13.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK70438.1 - 0.051 12.8 0.9 19 4.4 0.4 3.3 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK70438.1 - 0.073 12.3 0.2 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family DnaJ PF00226.31 KIK70439.1 - 1.8e-16 60.0 0.3 2.4e-16 59.6 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KIK70439.1 - 2e-13 49.8 0.5 3.3e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.6 KIK70439.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Exo84_C PF16528.5 KIK70441.1 - 9.7e-37 126.8 0.2 2.6e-36 125.4 0.2 1.8 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KIK70441.1 - 6e-17 61.5 3.0 1.4e-16 60.4 3.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KIK70441.1 - 5.4e-07 29.8 1.2 5.4e-07 29.8 1.2 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 KIK70441.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 KIK70441.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain RabGAP-TBC PF00566.18 KIK70442.1 - 5.4e-49 166.8 0.2 9.3e-49 166.0 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Flp1_like PF16982.5 KIK70442.1 - 0.029 13.7 0.2 0.05 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain TMEM171 PF15471.6 KIK70442.1 - 9.5 5.1 6.0 21 4.0 6.0 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 RNase_H PF00075.24 KIK70443.1 - 1.5e-32 112.7 0.0 3.4e-32 111.6 0.0 1.5 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 KIK70443.1 - 3.5e-09 36.8 0.0 9.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin ING PF12998.7 KIK70446.1 - 1.3e-15 57.8 0.1 2.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIK70446.1 - 1.4e-05 24.9 7.1 2.3e-05 24.2 7.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIK70446.1 - 0.026 14.1 1.3 0.042 13.4 1.3 1.3 1 0 0 1 1 1 0 PHD-finger DUF3583 PF12126.8 KIK70446.1 - 0.027 14.0 0.6 0.045 13.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) zf-HC5HC2H PF13771.6 KIK70446.1 - 0.055 13.7 1.9 0.12 12.7 1.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DASH_Dam1 PF08653.10 KIK70446.1 - 0.16 11.8 0.2 1.9 8.4 0.0 2.4 2 1 1 3 3 3 0 DASH complex subunit Dam1 dCMP_cyt_deam_1 PF00383.23 KIK70447.1 - 5.7e-17 61.5 0.2 7.2e-17 61.1 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KIK70447.1 - 6.6e-12 45.8 2.5 2.4e-10 40.7 0.5 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KIK70447.1 - 0.013 15.1 1.9 0.095 12.3 0.1 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases XOO_2897-deam PF14440.6 KIK70447.1 - 0.052 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC4_like PF18774.1 KIK70447.1 - 0.21 11.5 0.1 1.9 8.4 0.1 1.9 1 1 1 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase Fip1 PF05182.13 KIK70448.1 - 4.2e-19 67.8 1.1 6.6e-19 67.1 1.1 1.3 1 0 0 1 1 1 1 Fip1 motif SE PF08491.10 KIK70449.1 - 7.1e-88 294.2 0.0 9.6e-88 293.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KIK70449.1 - 1.1e-11 44.6 0.0 3.3e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK70449.1 - 1e-10 41.7 0.0 5e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK70449.1 - 6.6e-07 28.7 0.1 2.3e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK70449.1 - 3e-06 26.6 0.3 0.0055 15.8 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KIK70449.1 - 4.2e-05 22.9 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK70449.1 - 0.00034 20.0 0.4 0.0019 17.5 0.3 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK70449.1 - 0.00075 18.5 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KIK70449.1 - 0.0016 18.6 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK70449.1 - 0.0031 17.5 0.2 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 KIK70449.1 - 0.005 16.0 3.3 0.095 11.8 3.4 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A Csa1 PF06023.12 KIK70449.1 - 0.048 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Pyr_redox PF00070.27 KIK70449.1 - 0.051 14.1 0.4 1.2 9.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MciZ PF13072.6 KIK70449.1 - 0.094 12.5 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ GMC_oxred_N PF00732.19 KIK70449.1 - 0.1 12.0 0.5 4 6.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.6 KIK70449.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4129 PF13559.6 KIK70450.1 - 0.01 16.0 0.8 0.019 15.2 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) BTB PF00651.31 KIK70451.1 - 9.7e-08 32.2 0.0 2.4e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain FMN_dh PF01070.18 KIK70452.1 - 1.4e-118 395.9 0.0 1.7e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK70452.1 - 3.9e-21 75.0 0.0 7.3e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIK70452.1 - 3.5e-05 23.1 0.0 5.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIK70452.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Na_H_Exchanger PF00999.21 KIK70453.1 - 2e-47 161.8 41.3 2.9e-47 161.3 41.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Flavoprotein PF02441.19 KIK70454.1 - 1.6e-50 170.9 0.0 1.8e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein NAD_binding_7 PF13241.6 KIK70454.1 - 0.0022 18.4 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sel1 PF08238.12 KIK70455.1 - 3e-45 151.6 19.5 2.4e-08 34.4 0.2 8.2 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 KIK70455.1 - 0.11 12.8 2.8 1 9.6 0.2 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ADH_zinc_N PF00107.26 KIK70456.1 - 6.7e-12 45.5 0.2 1.4e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK70456.1 - 2.1e-07 30.8 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK70456.1 - 0.0098 16.9 0.0 0.018 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK70456.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ApbA PF02558.16 KIK70456.1 - 0.028 14.1 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_methylase PF00145.17 KIK70457.1 - 3.6e-32 112.0 0.0 6.6e-30 104.6 0.0 3.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIK70457.1 - 6.5e-06 26.0 0.1 0.00015 21.6 0.0 2.5 2 0 0 2 2 2 1 BAH domain DNMT1-RFD PF12047.8 KIK70457.1 - 3.7e-05 23.8 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Cons_hypoth95 PF03602.15 KIK70457.1 - 0.009 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Cbl_N PF02262.16 KIK70457.1 - 0.13 12.2 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 G-alpha PF00503.20 KIK70458.1 - 9.9e-117 390.0 1.7 1.1e-116 389.9 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK70458.1 - 2.3e-14 53.2 0.1 2.6e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK70458.1 - 0.0012 18.2 0.0 0.85 8.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK70458.1 - 0.0044 17.2 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase CagD PF16567.5 KIK70458.1 - 0.039 13.7 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 Pathogenicity island component CagD AAA_29 PF13555.6 KIK70458.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KIK70458.1 - 0.089 12.3 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Calreticulin PF00262.18 KIK70459.1 - 5.3e-161 535.5 6.1 7.1e-161 535.1 6.1 1.2 1 0 0 1 1 1 1 Calreticulin family HMG_box PF00505.19 KIK70460.1 - 8.3e-08 32.5 1.7 1.3e-07 31.9 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 KIK70460.1 - 6.8e-07 30.0 0.7 6.8e-07 30.0 0.7 1.6 1 1 1 2 2 2 1 YABBY protein HMG_box_2 PF09011.10 KIK70460.1 - 8.3e-05 23.1 2.1 0.00015 22.3 2.1 1.6 1 1 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KIK70460.1 - 0.00016 22.3 0.3 0.00016 22.3 0.3 1.8 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 PsbT PF01405.17 KIK70461.1 - 0.99 9.3 2.4 2.3 8.1 2.4 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Clr2_transil PF16761.5 KIK70462.1 - 3.7e-17 62.9 0.4 8.7e-17 61.7 0.4 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 FAD_binding_3 PF01494.19 KIK70463.1 - 7e-14 51.8 0.1 1.1e-12 47.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK70463.1 - 1.1e-05 25.6 0.3 3.5e-05 23.9 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK70463.1 - 0.00011 21.6 0.5 0.0029 16.9 0.5 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK70463.1 - 0.00012 22.1 0.1 0.00034 20.7 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KIK70463.1 - 0.0023 17.3 0.0 0.007 15.7 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KIK70463.1 - 0.0045 16.6 1.9 0.011 15.3 1.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK70463.1 - 0.032 13.1 1.7 0.47 9.3 0.6 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KIK70463.1 - 0.043 14.4 0.3 0.1 13.1 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK70463.1 - 0.045 12.8 2.0 0.072 12.2 2.0 1.3 1 0 0 1 1 1 0 FAD binding domain Minor_capsid_2 PF11114.8 KIK70463.1 - 0.08 13.0 0.3 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Minor capsid protein AlaDh_PNT_C PF01262.21 KIK70463.1 - 0.11 11.8 0.3 0.22 10.8 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK70463.1 - 0.15 11.3 0.2 0.25 10.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KIK70463.1 - 0.17 10.6 0.9 0.27 9.9 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein GTP_EFTU PF00009.27 KIK70464.1 - 8.5e-44 149.4 0.0 1.3e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KIK70464.1 - 3.4e-37 127.7 2.0 5.4e-37 127.1 2.0 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KIK70464.1 - 6.1e-24 84.1 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KIK70464.1 - 2.3e-22 78.8 0.0 5.8e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK70464.1 - 2.8e-10 40.5 0.0 5.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK70464.1 - 1.9e-06 27.9 0.1 4e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KIK70464.1 - 5.9e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KIK70464.1 - 0.0084 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KIK70464.1 - 0.052 13.6 0.1 3.6 7.6 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Prefoldin_2 PF01920.20 KIK70465.1 - 1e-16 60.8 8.9 1.2e-16 60.6 8.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 KIK70465.1 - 0.0027 17.6 4.4 0.0032 17.4 4.4 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Tropomyosin_1 PF12718.7 KIK70465.1 - 0.0083 16.3 1.5 0.0083 16.3 1.5 2.0 2 0 0 2 2 2 1 Tropomyosin like Prefoldin PF02996.17 KIK70465.1 - 0.046 13.6 5.4 3.8 7.4 0.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit FAM91_C PF14648.6 KIK70465.1 - 0.054 12.3 1.2 0.062 12.1 1.2 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Csm1_B PF18211.1 KIK70465.1 - 0.061 13.2 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 Csm1 subunit domain B HisKA_3 PF07730.13 KIK70465.1 - 0.076 13.5 2.0 1.1 9.8 0.1 2.2 2 0 0 2 2 2 0 Histidine kinase Coat_F PF07875.12 KIK70465.1 - 0.15 12.3 1.8 2.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Coat F domain Seryl_tRNA_N PF02403.22 KIK70465.1 - 0.27 11.5 7.7 0.48 10.7 7.7 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF5320 PF17253.2 KIK70465.1 - 0.64 11.1 2.9 1.8 9.6 2.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) UCH PF00443.29 KIK70466.1 - 7.7e-40 137.0 0.0 1.3e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KIK70466.1 - 8.8e-25 86.2 0.4 2.7e-12 46.3 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KIK70466.1 - 1.8e-24 85.8 15.7 1.2e-19 70.4 1.5 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KIK70466.1 - 3.2e-22 78.0 4.8 3.7e-22 77.8 1.0 2.4 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 KIK70466.1 - 3.6e-16 59.6 2.1 4.5e-14 52.8 0.1 3.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-C2HE PF16278.5 KIK70466.1 - 0.02 15.3 0.7 8.9 6.9 0.1 3.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger UBA_4 PF14555.6 KIK70466.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain TetR_C_30 PF17939.1 KIK70467.1 - 0.052 13.8 0.2 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SIKE PF05769.11 KIK70469.1 - 3.3e-12 46.7 11.3 2.1e-08 34.3 7.5 2.3 2 0 0 2 2 2 2 SIKE family NYD-SP28_assoc PF14775.6 KIK70469.1 - 0.0027 17.8 7.7 0.19 11.9 2.0 2.8 2 0 0 2 2 2 2 Sperm tail C-terminal domain bZIP_1 PF00170.21 KIK70469.1 - 0.063 13.4 5.5 5.7 7.1 0.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor PikAIV_N PF18605.1 KIK70469.1 - 0.12 11.9 8.3 0.22 11.1 0.1 3.0 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain bZIP_2 PF07716.15 KIK70469.1 - 0.24 11.5 7.3 0.38 10.9 0.6 3.0 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 KIK70469.1 - 0.32 11.4 6.1 6.1 7.2 0.1 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 KIK70469.1 - 1.3 9.7 12.1 3.4 8.4 3.0 3.4 2 1 2 4 4 4 0 Initiation control protein YabA MCC-bdg_PDZ PF10506.9 KIK70469.1 - 1.7 8.7 6.5 0.57 10.2 0.7 2.9 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cnn_1N PF07989.11 KIK70469.1 - 3.5 7.8 12.7 2.3 8.4 2.2 3.5 3 2 0 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KIK70469.1 - 4.1 7.2 12.7 13 5.7 0.6 4.2 5 0 0 5 5 5 0 Septum formation initiator ZapB PF06005.12 KIK70469.1 - 9.6 6.7 12.2 8.1 7.0 3.7 3.0 3 1 0 3 3 3 0 Cell division protein ZapB NCBP3 PF10309.9 KIK70470.1 - 2e-06 27.6 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KIK70470.1 - 7.7e-05 22.6 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain DSHCT PF08148.12 KIK70472.1 - 3.6e-52 176.4 0.3 8.2e-52 175.2 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KIK70472.1 - 2.4e-34 118.1 0.0 4.1e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KIK70472.1 - 5.5e-32 111.8 0.2 9e-32 111.1 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KIK70472.1 - 2.2e-19 69.9 0.1 4.7e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK70472.1 - 7.4e-07 29.3 0.1 2.2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK70472.1 - 5.2e-06 26.8 0.0 3.5e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 KIK70472.1 - 0.068 12.2 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Methyltransf_23 PF13489.6 KIK70473.1 - 7.2e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK70473.1 - 9.8e-07 29.4 0.0 3e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK70473.1 - 1.2e-06 29.1 0.0 4e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK70473.1 - 9.5e-06 25.5 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIK70473.1 - 0.00021 20.8 0.0 0.00073 19.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 KIK70473.1 - 0.00029 21.4 0.0 0.00065 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIK70473.1 - 0.0004 20.6 0.0 0.00062 19.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIK70473.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIK70473.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KIK70473.1 - 0.048 13.0 0.0 0.83 8.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ist1 PF03398.14 KIK70474.1 - 2.9e-62 209.4 0.5 3.8e-62 209.0 0.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Indigoidine_A PF04227.12 KIK70474.1 - 0.11 11.9 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein RasGEF PF00617.19 KIK70475.1 - 1.6e-39 135.9 0.0 4.4e-39 134.5 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIK70475.1 - 5e-12 46.0 1.0 1.4e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 KIK70475.1 - 3.8e-08 32.8 0.0 9.1e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK70475.1 - 1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK70475.1 - 0.05 13.5 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain Ras PF00071.22 KIK70476.1 - 1.3e-59 200.4 0.1 1.5e-59 200.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK70476.1 - 1.2e-36 125.6 0.0 1.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK70476.1 - 9e-14 51.3 0.1 1.1e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK70476.1 - 1.5e-06 28.3 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK70476.1 - 7.1e-06 26.0 0.2 0.064 13.2 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 KIK70476.1 - 1.6e-05 24.3 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK70476.1 - 6.1e-05 22.6 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIK70476.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KIK70476.1 - 0.039 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin TniB PF05621.11 KIK70476.1 - 0.057 12.8 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 KIK70476.1 - 0.082 12.3 0.1 0.23 10.9 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RRM_1 PF00076.22 KIK70477.1 - 1.2e-14 53.9 0.0 1.5e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK70477.1 - 0.0029 17.6 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MRP-L28 PF09812.9 KIK70478.1 - 2.7e-09 37.4 2.8 1.1e-07 32.1 2.9 2.3 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L28 ARA70 PF12489.8 KIK70478.1 - 0.072 13.3 0.1 0.099 12.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear coactivator Thymidylate_kin PF02223.17 KIK70478.1 - 0.073 12.7 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Thymidylate kinase Nup188 PF10487.9 KIK70479.1 - 7.5e-49 166.5 0.0 7.4e-36 123.5 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KIK70479.1 - 6.9e-08 31.7 0.1 1.5e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain bVLRF1 PF18826.1 KIK70479.1 - 0.056 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Ribosomal_L1 PF00687.21 KIK70480.1 - 1.2e-21 77.4 0.0 2.7e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Rsm22 PF09243.10 KIK70481.1 - 2.8e-46 158.0 0.0 8e-32 110.6 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.29 KIK70482.1 - 3.5e-27 95.5 0.0 5.2e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIK70482.1 - 5.5e-11 42.6 0.1 1.2e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DND1_DSRM PF14709.7 KIK70484.1 - 0.029 14.6 0.2 0.039 14.2 0.2 1.2 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KIK70484.1 - 0.039 14.7 4.4 0.058 14.1 4.4 1.6 1 1 0 1 1 1 0 Double-stranded RNA binding motif dsrm PF00035.26 KIK70485.1 - 4.7e-09 36.8 0.1 6.8e-09 36.3 0.0 1.2 1 1 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KIK70486.1 - 1.4e-10 41.7 0.0 1.6e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif LPP20 PF02169.16 KIK70486.1 - 0.013 15.8 0.2 0.022 15.1 0.1 1.4 2 0 0 2 2 2 0 LPP20 lipoprotein WD40 PF00400.32 KIK70487.1 - 1.8e-39 133.0 18.4 2.2e-07 31.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70487.1 - 1.6e-16 60.4 0.0 0.0049 17.1 0.1 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK70487.1 - 0.00012 21.1 0.8 0.17 10.8 0.0 3.6 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK70487.1 - 0.00057 19.8 0.0 0.29 11.0 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK70487.1 - 0.00092 18.6 0.0 0.23 10.8 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 KIK70487.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain CENP-F_leu_zip PF10473.9 KIK70488.1 - 0.0019 18.2 47.2 0.47 10.5 6.7 3.2 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DMPK_coil PF08826.10 KIK70488.1 - 0.0024 17.9 5.3 0.0024 17.9 5.3 5.4 2 1 3 6 6 6 1 DMPK coiled coil domain like Myosin_tail_1 PF01576.19 KIK70488.1 - 0.0092 13.9 40.2 0.013 13.3 40.2 1.1 1 0 0 1 1 1 1 Myosin tail bZIP_1 PF00170.21 KIK70488.1 - 0.041 14.0 2.3 0.041 14.0 2.3 6.3 1 1 7 8 8 8 0 bZIP transcription factor IMP_cyclohyd PF07826.11 KIK70488.1 - 0.042 13.5 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein DUF1664 PF07889.12 KIK70488.1 - 0.068 13.2 25.6 0.16 12.0 7.1 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KIK70488.1 - 0.16 12.3 29.1 0.12 12.7 4.7 3.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.9 KIK70488.1 - 0.35 10.3 41.5 0.28 10.6 26.1 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 APG6_N PF17675.1 KIK70488.1 - 0.43 11.1 51.9 6.8 7.2 21.5 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region GTP-bdg_M PF16360.5 KIK70488.1 - 0.5 11.0 24.0 3 8.5 5.4 4.9 2 1 2 4 4 4 0 GTP-binding GTPase Middle Region KASH_CCD PF14662.6 KIK70488.1 - 0.54 10.1 47.0 0.062 13.1 34.9 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 KIK70488.1 - 0.55 9.7 36.7 0.27 10.7 13.0 2.2 1 1 1 2 2 2 0 Leucine zipper Filament PF00038.21 KIK70488.1 - 0.55 9.8 35.5 5 6.6 34.2 2.1 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 KIK70488.1 - 0.66 8.8 43.9 0.85 8.4 22.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Rab5-bind PF09311.11 KIK70488.1 - 0.67 9.3 38.2 1.7 8.0 12.6 2.2 1 1 1 2 2 2 0 Rabaptin-like protein DUF5082 PF16888.5 KIK70488.1 - 1.2 9.4 35.9 3.5 7.9 16.3 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Hemerythrin PF01814.23 KIK70488.1 - 1.5 9.5 10.2 3.3 8.3 0.9 3.4 2 2 1 3 3 3 0 Hemerythrin HHE cation binding domain YabA PF06156.13 KIK70488.1 - 1.6 9.4 36.0 7.8 7.2 6.0 4.2 1 1 3 4 4 4 0 Initiation control protein YabA Atg14 PF10186.9 KIK70488.1 - 1.6 7.7 38.4 1.2e+03 -1.7 38.5 2.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KIK70488.1 - 1.9 8.7 49.5 1.9 8.7 11.4 3.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TLE_N PF03920.15 KIK70488.1 - 1.9 8.5 15.0 0.51 10.4 1.3 3.4 1 1 2 3 3 3 0 Groucho/TLE N-terminal Q-rich domain HOOK PF05622.12 KIK70488.1 - 2.3 6.3 39.2 1.1 7.3 13.4 2.1 1 1 1 2 2 2 0 HOOK protein Fez1 PF06818.15 KIK70488.1 - 2.4 8.6 39.0 1.7 9.1 22.9 2.3 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 KIK70488.1 - 2.5 7.4 41.2 0.47 9.8 22.4 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 KIK70488.1 - 2.8 7.6 47.4 0.096 12.3 36.9 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fibin PF15819.5 KIK70488.1 - 3.1 7.5 11.4 2.1 8.0 9.3 1.7 1 1 0 1 1 1 0 Fin bud initiation factor homologue DLP_helical PF18709.1 KIK70488.1 - 3.3 6.8 23.3 0.24 10.5 13.3 2.8 1 1 1 2 2 2 0 Dynamin-like helical domain ZapB PF06005.12 KIK70488.1 - 5.5 7.5 52.1 0.15 12.6 1.7 4.9 1 1 3 4 4 4 0 Cell division protein ZapB DUF3450 PF11932.8 KIK70488.1 - 5.6 6.2 39.3 1.4 8.1 13.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HMMR_N PF15905.5 KIK70488.1 - 6.1 6.2 39.8 1.2 8.6 23.2 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Uso1_p115_C PF04871.13 KIK70488.1 - 6.4 7.2 46.5 18 5.7 21.8 3.4 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Bacillus_HBL PF05791.11 KIK70488.1 - 7 6.4 20.0 9 6.1 5.3 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CENP-K PF11802.8 KIK70488.1 - 8.2 5.9 37.4 0.48 10.0 22.8 2.1 1 1 1 2 2 2 0 Centromere-associated protein K DUF4407 PF14362.6 KIK70488.1 - 9 5.5 30.7 3.4 6.9 16.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KIK70488.1 - 9.9 3.5 36.6 20 2.5 36.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.15 KIK70489.1 - 0.0076 16.0 2.3 0.0076 16.0 2.3 1.5 1 1 0 2 2 2 1 Septum formation initiator APG6_N PF17675.1 KIK70489.1 - 0.036 14.6 8.6 0.041 14.4 8.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region LPP PF04728.13 KIK70489.1 - 0.067 13.6 8.4 6 7.3 8.4 2.3 1 1 0 1 1 1 0 Lipoprotein leucine-zipper BRE1 PF08647.11 KIK70489.1 - 0.085 12.9 8.8 0.087 12.9 7.9 1.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-Q PF13094.6 KIK70489.1 - 0.091 13.0 9.0 0.2 11.8 9.0 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 KIK70489.1 - 0.19 11.8 10.1 0.23 11.5 10.1 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KIK70489.1 - 0.26 11.6 7.9 0.29 11.5 7.9 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lectin_N PF03954.14 KIK70489.1 - 0.3 10.8 8.3 1.1 9.0 3.2 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain SlyX PF04102.12 KIK70489.1 - 0.62 10.7 7.2 0.8 10.4 7.2 1.2 1 0 0 1 1 1 0 SlyX Pyr_redox_2 PF07992.14 KIK70490.1 - 2.5e-26 92.6 0.0 2.3e-24 86.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK70490.1 - 3.2e-11 43.6 0.0 9.1e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK70490.1 - 0.0061 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KIK70490.1 - 0.0078 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK70490.1 - 0.079 12.5 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase PLDc PF00614.22 KIK70491.1 - 6.6e-18 64.1 1.5 5.3e-09 35.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KIK70491.1 - 3.9e-17 62.4 0.1 1.3e-07 31.5 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PNK3P PF08645.11 KIK70491.1 - 0.017 14.8 0.1 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Phage_terminase PF10668.9 KIK70491.1 - 0.076 13.0 0.0 0.33 11.0 0.0 2.1 1 0 0 1 1 1 0 Phage terminase small subunit APC1_C PF18122.1 KIK70494.1 - 2.6e-30 105.5 0.1 4.8e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KIK70494.1 - 4.5e-07 30.5 0.0 4.5e-07 30.5 0.0 2.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KIK70494.1 - 0.00026 21.3 8.5 0.91 10.1 0.0 4.4 4 0 0 4 4 4 3 Proteasome/cyclosome repeat NOG1_N PF17835.1 KIK70495.1 - 2.7e-49 167.2 0.7 2.7e-49 167.2 0.7 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KIK70495.1 - 5e-27 93.4 0.0 1.2e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KIK70495.1 - 3.4e-26 91.0 2.4 3.4e-26 91.0 2.4 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KIK70495.1 - 2.1e-17 63.3 0.0 5.2e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK70495.1 - 1.2e-09 37.9 0.1 2.9e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK70495.1 - 0.0015 18.5 0.1 0.78 9.6 0.0 3.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK70495.1 - 0.0065 16.5 0.0 2 8.5 0.0 2.9 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 KIK70495.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.9 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 KIK70495.1 - 0.047 14.1 0.1 0.67 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Sushi_2 PF09014.10 KIK70495.1 - 0.05 13.5 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 KIK70495.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family HHH_9 PF17674.1 KIK70495.1 - 0.3 12.0 2.5 0.35 11.8 0.5 2.2 2 0 0 2 2 1 0 HHH domain SPT6_acidic PF14632.6 KIK70495.1 - 0.41 11.3 11.4 2.7 8.6 1.1 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 tRNA-synt_2b PF00587.25 KIK70496.1 - 5.7e-10 39.4 0.0 5.7e-08 32.9 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIK70496.1 - 0.076 13.3 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PCI PF01399.27 KIK70497.1 - 1e-19 71.0 0.3 2.7e-19 69.6 0.3 1.8 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 KIK70497.1 - 0.025 14.9 6.5 0.12 12.7 0.7 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5517) polyprenyl_synt PF00348.17 KIK70498.1 - 8.3e-22 77.5 0.0 6.1e-17 61.5 0.0 2.9 2 1 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KIK70498.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 MMM1 PF10296.9 KIK70501.1 - 7e-09 35.2 0.0 2.9e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_9 PF15410.6 KIK70501.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PIP5K PF01504.18 KIK70502.1 - 7e-45 153.4 0.5 4.5e-36 124.5 0.4 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KIK70502.1 - 2.4e-28 99.0 0.0 4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KIK70502.1 - 2.8e-18 65.8 11.6 4.6e-18 65.1 10.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger HK_sensor PF16750.5 KIK70502.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase IBR PF01485.21 KIK70502.1 - 0.16 12.2 8.4 0.53 10.5 8.4 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Dehydrin PF00257.19 KIK70502.1 - 1.1 9.8 5.3 1.1 9.8 3.2 2.0 2 0 0 2 2 2 0 Dehydrin FYVE_2 PF02318.16 KIK70502.1 - 2.8 8.2 7.1 8.2 6.7 7.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Bromodomain PF00439.25 KIK70503.1 - 1.7e-57 191.5 0.0 1.4e-18 66.7 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KIK70503.1 - 3.9e-08 33.1 0.0 6.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIK70503.1 - 6.2e-05 23.3 0.1 0.019 15.1 0.0 2.4 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 KIK70503.1 - 0.013 15.9 5.2 1.1 9.7 0.3 3.3 3 0 0 3 3 3 0 HEAT repeats LTV PF04180.14 KIK70504.1 - 6.5e-93 312.5 13.9 6.2e-89 299.4 7.0 2.1 1 1 1 2 2 2 2 Low temperature viability protein Herpes_UL56 PF04534.12 KIK70504.1 - 0.039 13.4 0.7 0.082 12.4 0.7 1.6 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF4662 PF15578.6 KIK70504.1 - 0.41 10.4 4.9 0.73 9.6 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) OCD_Mu_crystall PF02423.15 KIK70506.1 - 3.2e-27 95.3 0.4 3.4e-23 82.1 0.1 2.1 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KIK70506.1 - 0.00077 19.5 0.1 0.0041 17.2 0.0 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ORC2 PF04084.14 KIK70508.1 - 9.1e-95 317.4 0.1 1.1e-94 317.1 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Med11 PF10280.9 KIK70512.1 - 0.0023 18.4 0.1 0.0051 17.3 0.0 1.6 1 1 0 1 1 1 1 Mediator complex protein DASH_Dam1 PF08653.10 KIK70513.1 - 9.9e-23 79.7 0.3 1.7e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4519 PF15012.6 KIK70513.1 - 0.044 14.0 1.3 0.076 13.2 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) TBCA PF02970.16 KIK70515.1 - 1.1e-21 76.9 2.0 1.3e-21 76.7 1.5 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF919 PF06034.11 KIK70515.1 - 0.017 14.9 0.8 0.033 14.0 0.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF948 PF06103.11 KIK70515.1 - 0.038 14.3 1.1 0.17 12.2 0.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HLH PF00010.26 KIK70517.1 - 7.8e-12 45.0 2.3 7.8e-12 45.0 2.3 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4482 PF14818.6 KIK70517.1 - 0.012 16.5 0.9 0.061 14.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) GIT_CC PF16559.5 KIK70517.1 - 0.025 14.4 2.7 0.056 13.3 2.3 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1192 PF06698.11 KIK70517.1 - 0.084 12.9 0.5 0.66 10.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FapA PF03961.13 KIK70517.1 - 0.09 11.4 2.1 0.12 10.9 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mst1_SARAH PF11629.8 KIK70517.1 - 0.18 11.9 2.5 0.39 10.8 0.4 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 TFIIA PF03153.13 KIK70517.1 - 3.6 7.5 11.4 4.3 7.2 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 KIK70517.1 - 4 6.7 6.1 9.8 5.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 KIK70517.1 - 5.3 7.5 8.1 14 6.1 8.1 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 HLH PF00010.26 KIK70519.1 - 1.6e-09 37.5 1.2 1.6e-09 37.5 1.2 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain BLOC1_2 PF10046.9 KIK70519.1 - 0.069 13.4 0.8 1.7 9.0 0.1 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 KIK70519.1 - 0.11 12.8 6.0 0.36 11.1 6.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Adaptin_N PF01602.20 KIK70520.1 - 3.5e-114 382.2 0.0 4.9e-114 381.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KIK70520.1 - 3.5e-57 192.8 0.7 9.2e-57 191.4 0.7 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KIK70520.1 - 5.4e-35 120.0 0.0 1.5e-34 118.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KIK70520.1 - 3.2e-18 65.9 2.5 2.2e-10 40.8 0.0 5.9 3 2 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KIK70520.1 - 7.2e-08 32.6 3.4 0.012 15.6 0.2 4.4 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK70520.1 - 0.00079 19.5 6.9 5.2 7.6 0.2 6.0 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.23 KIK70520.1 - 0.015 15.3 0.2 54 4.0 0.0 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KIK70520.1 - 0.051 14.3 2.1 15 6.6 0.0 5.4 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Pkinase PF00069.25 KIK70521.1 - 2.9e-26 92.4 0.0 3.6e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70521.1 - 1.8e-13 50.4 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK70521.1 - 2.3e-09 36.6 0.1 3.6e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK70521.1 - 0.0012 18.8 0.0 0.0076 16.2 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIK70521.1 - 0.023 13.7 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KIK70521.1 - 0.09 12.1 0.7 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_1 PF01644.17 KIK70522.1 - 1.4e-71 239.7 0.2 2.2e-71 239.1 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK70522.1 - 1.2e-27 95.7 0.0 5.2e-27 93.6 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK70522.1 - 1.2e-18 67.1 0.3 5.5e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK70522.1 - 7.9e-08 32.5 0.2 7.9e-08 32.5 0.2 3.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK70522.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Fumble PF03630.14 KIK70525.1 - 3.6e-133 443.8 0.0 4.4e-133 443.5 0.0 1.1 1 0 0 1 1 1 1 Fumble Homeodomain PF00046.29 KIK70526.1 - 2.3e-44 149.0 10.5 7.4e-15 54.5 0.2 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KIK70526.1 - 8.8e-13 47.9 2.3 0.0002 21.2 0.1 4.0 3 1 1 4 4 4 3 Homeobox KN domain HOCHOB PF17943.1 KIK70526.1 - 7.1e-07 30.0 0.0 0.25 12.1 0.0 3.3 3 0 0 3 3 3 2 Homeobox-cysteine loop-homeobox YdaS_antitoxin PF15943.5 KIK70526.1 - 3.6e-06 26.8 0.2 0.29 11.0 0.0 3.3 3 0 0 3 3 3 3 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KIK70526.1 - 0.0042 17.1 0.2 12 6.1 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix Phage_CI_repr PF07022.13 KIK70526.1 - 0.079 13.1 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain FAM176 PF14851.6 KIK70526.1 - 0.14 11.8 4.3 2.7 7.6 0.4 2.8 2 1 0 2 2 2 0 FAM176 family Pyr_redox_3 PF13738.6 KIK70529.1 - 7.1e-16 58.3 0.0 1.4e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK70529.1 - 9.5e-16 57.3 0.0 2.6e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK70529.1 - 1.6e-11 44.0 0.0 1.5e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK70529.1 - 3.7e-09 36.2 0.2 7.6e-08 31.9 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK70529.1 - 3.9e-07 30.2 1.0 1.2e-06 28.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK70529.1 - 4.7e-06 27.1 2.4 0.084 13.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK70529.1 - 0.0036 16.4 2.5 0.0048 16.0 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIK70529.1 - 0.0068 15.7 0.2 2 7.7 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KIK70529.1 - 0.011 15.8 0.0 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KIK70529.1 - 0.081 12.3 0.1 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KIK70529.1 - 0.16 11.0 3.6 0.62 9.1 1.2 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KIK70529.1 - 0.19 11.7 3.0 1.2 9.1 0.3 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KIK70529.1 - 0.22 10.2 1.0 3.1 6.4 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KIK70529.1 - 0.26 11.2 0.4 0.41 10.5 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KIK70529.1 - 0.87 9.1 10.9 0.021 14.4 3.0 2.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase ICL PF00463.21 KIK70530.1 - 3.4e-190 633.0 0.0 3.9e-190 632.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIK70530.1 - 3.3e-09 36.5 0.0 2.4e-08 33.7 0.0 2.3 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase PapA_C PF16911.5 KIK70530.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus cNMP_binding PF00027.29 KIK70532.1 - 1.6e-30 105.0 0.0 5e-16 58.5 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KIK70532.1 - 2.5e-18 67.0 2.5 5.1e-13 49.7 1.1 2.8 2 0 0 2 2 2 2 Patatin-like phospholipase Wzy_C PF04932.15 KIK70532.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 O-Antigen ligase Sec1 PF00995.23 KIK70533.1 - 1.7e-116 390.7 0.0 2.2e-116 390.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peripla_BP_4 PF13407.6 KIK70533.1 - 0.035 13.7 0.2 0.081 12.5 0.1 1.6 2 0 0 2 2 2 0 Periplasmic binding protein domain CAP_N PF01213.19 KIK70533.1 - 1.9 7.9 6.1 4.9 6.5 5.8 1.8 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal YABBY PF04690.13 KIK70534.1 - 2.1e-09 38.2 0.3 2.2e-09 38.1 0.3 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KIK70534.1 - 0.00017 22.2 2.1 0.00021 21.9 2.1 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KIK70534.1 - 0.0012 19.2 0.3 0.0019 18.6 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box F-box-like PF12937.7 KIK70535.1 - 6.8e-07 29.1 0.3 1.8e-06 27.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK70535.1 - 5.2e-05 23.5 4.1 6.6 7.3 0.0 5.3 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK70535.1 - 0.0053 16.7 13.1 2.2 8.6 0.0 7.2 8 0 0 8 8 8 1 Leucine Rich repeat F-box PF00646.33 KIK70535.1 - 0.037 13.9 0.2 0.12 12.2 0.2 1.9 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 KIK70535.1 - 0.5 11.1 6.7 57 4.8 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Sas10_Utp3 PF04000.15 KIK70537.1 - 1.6e-16 60.7 0.0 4.9e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family baeRF_family8 PF18851.1 KIK70537.1 - 0.083 13.0 0.8 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 XRN_M PF17846.1 KIK70537.1 - 0.11 11.4 0.1 0.11 11.4 0.1 2.0 2 0 0 2 2 2 0 Xrn1 helical domain Methyltransf_25 PF13649.6 KIK70538.1 - 2.6e-12 47.3 0.0 6e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK70538.1 - 8.1e-09 36.0 0.0 2.7e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK70538.1 - 4.5e-06 26.2 0.0 7.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK70538.1 - 1.9e-05 24.5 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK70538.1 - 2.5e-05 24.2 0.0 7.3e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK70538.1 - 3.1e-05 23.4 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KIK70538.1 - 0.00041 19.9 0.0 0.0041 16.6 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 KIK70538.1 - 0.00046 20.9 0.0 0.0012 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIK70538.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Phage_holin_2_2 PF10746.9 KIK70538.1 - 0.13 11.9 0.6 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II Methyltransf_29 PF03141.16 KIK70538.1 - 0.23 10.0 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WLM PF08325.10 KIK70539.1 - 3.4e-59 200.1 0.0 4.3e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KIK70539.1 - 2.1e-06 26.9 0.9 2.1e-06 26.9 0.9 3.1 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KIK70539.1 - 0.0026 17.8 0.1 0.016 15.2 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 SVIP PF15811.5 KIK70539.1 - 0.059 13.8 4.8 1.1 9.8 0.1 2.5 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DZR PF12773.7 KIK70539.1 - 0.5 10.4 5.7 0.97 9.5 5.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 KIK70539.1 - 0.54 10.6 6.3 4 7.8 1.0 2.5 1 1 1 2 2 2 0 C1 domain zf-4CXXC_R1 PF10497.9 KIK70539.1 - 0.68 10.2 6.1 3.5 7.9 6.1 2.2 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Methyltransf_16 PF10294.9 KIK70540.1 - 2.5e-14 53.4 0.0 5.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KIK70540.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAM86 PF14904.6 KIK70540.1 - 0.00035 20.6 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function MTS PF05175.14 KIK70540.1 - 0.0067 16.0 0.2 0.085 12.4 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 KIK70540.1 - 0.0087 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KIK70540.1 - 0.2 12.4 0.0 0.65 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Bot1p PF12298.8 KIK70541.1 - 8.1e-27 94.5 0.0 1.6e-26 93.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 KIK70541.1 - 7.6e-06 26.2 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MFS_1 PF07690.16 KIK70542.1 - 2.8e-21 75.9 21.1 4e-21 75.3 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Med5 PF08689.10 KIK70542.1 - 0.067 11.0 0.7 0.091 10.6 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 LrgA PF03788.14 KIK70542.1 - 4.9 7.2 9.5 0.68 9.9 2.5 2.8 3 0 0 3 3 3 0 LrgA family Cpn60_TCP1 PF00118.24 KIK70543.1 - 4.1e-157 523.8 1.8 4.6e-157 523.6 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.23 KIK70544.1 - 5.2e-65 219.5 0.0 6.8e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIK70544.1 - 6.7e-12 45.2 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KIK70544.1 - 1.3e-10 41.6 0.1 4.3e-10 39.9 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KIK70544.1 - 4.4e-06 26.4 15.4 7.2e-05 22.6 15.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK70544.1 - 5.5e-06 26.1 15.7 1e-05 25.3 15.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KIK70544.1 - 1.3e-05 25.2 0.0 7e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK70544.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 KIK70544.1 - 7.6e-05 22.7 12.5 0.00013 21.9 11.3 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK70544.1 - 0.00015 21.8 15.1 0.00032 20.8 15.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK70544.1 - 0.00061 20.1 14.3 0.0012 19.1 14.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK70544.1 - 0.0011 18.7 12.5 0.0019 18.0 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK70544.1 - 0.017 15.1 12.8 0.03 14.3 12.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 KIK70544.1 - 0.077 12.8 8.7 0.17 11.7 8.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KIK70544.1 - 0.49 10.2 9.1 0.87 9.4 9.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger HLH PF00010.26 KIK70545.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 KIK70546.1 - 5.1e-16 58.5 45.5 8.3e-11 41.4 16.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK70546.1 - 0.00085 18.7 25.8 0.0016 17.8 11.4 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB HLH PF00010.26 KIK70547.1 - 6.4e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Adeno_E1A PF02703.14 KIK70547.1 - 0.014 15.0 8.5 0.02 14.5 8.5 1.2 1 0 0 1 1 1 0 Early E1A protein CytochromB561_N PF09786.9 KIK70547.1 - 0.28 10.1 13.4 0.34 9.8 13.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SPX PF03105.19 KIK70547.1 - 0.37 10.7 14.0 0.45 10.4 14.0 1.1 1 0 0 1 1 1 0 SPX domain DUF4698 PF15769.5 KIK70547.1 - 1.4 7.9 3.8 1.8 7.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Rrn6 PF10214.9 KIK70547.1 - 1.6 7.2 16.5 2 6.8 16.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SOG2 PF10428.9 KIK70547.1 - 2.7 7.1 15.8 3.5 6.7 15.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KIK70547.1 - 3.5 6.2 10.7 3.9 6.0 10.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SecD-TM1 PF13721.6 KIK70549.1 - 0.14 12.7 2.3 0.16 12.5 2.3 1.1 1 0 0 1 1 1 0 SecD export protein N-terminal TM region BSP PF04450.12 KIK70550.1 - 2.5e-44 151.5 0.0 4.9e-42 144.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase of plants and bacteria FAA_hydro_N_2 PF18288.1 KIK70551.1 - 0.097 13.1 0.3 0.52 10.8 0.0 2.3 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 ComR_TPR PF18710.1 KIK70551.1 - 0.21 11.1 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 ComR tetratricopeptide NIF PF03031.18 KIK70552.1 - 1.2e-20 73.9 0.0 1e-19 70.8 0.0 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KIK70552.1 - 1.4e-08 34.6 0.2 4.8e-08 32.8 0.3 1.9 2 0 0 2 2 2 1 twin BRCT domain APH PF01636.23 KIK70552.1 - 1.5e-07 31.6 0.0 4.3e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family BRCT PF00533.26 KIK70552.1 - 5.2e-06 26.7 0.1 2.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF1679 PF07914.11 KIK70552.1 - 9.1e-05 21.5 0.0 0.00021 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KIK70552.1 - 0.0039 16.5 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 KIK70552.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase GTP_EFTU PF00009.27 KIK70553.1 - 1.1e-49 168.6 0.2 1.6e-49 168.1 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIK70553.1 - 7.2e-34 116.2 0.0 4.6e-33 113.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KIK70553.1 - 3.8e-22 78.1 0.0 8.4e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIK70553.1 - 3.1e-14 52.8 0.0 7.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIK70553.1 - 1.6e-12 47.6 0.0 5e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK70553.1 - 0.075 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FA_hydroxylase PF04116.13 KIK70554.1 - 1.5e-21 77.1 20.9 1.5e-21 77.1 20.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SH3_1 PF00018.28 KIK70556.1 - 1.3e-10 40.7 0.1 2.1e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK70556.1 - 5.3e-08 32.4 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK70556.1 - 9.4e-08 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CPBP PF02517.16 KIK70557.1 - 0.038 14.4 3.4 0.047 14.1 3.4 1.3 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease DUF2632 PF10943.8 KIK70557.1 - 0.12 11.9 4.5 0.13 11.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) UL20 PF17582.2 KIK70557.1 - 0.21 10.8 5.5 0.22 10.8 5.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL20 Nramp PF01566.18 KIK70558.1 - 1.6e-59 201.7 12.6 4.3e-40 137.8 5.8 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Nramp PF01566.18 KIK70559.1 - 0.00082 18.4 1.5 0.001 18.1 1.5 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein GSAP-16 PF14959.6 KIK70559.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term DUF2937 PF11157.8 KIK70560.1 - 0.27 10.9 1.2 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) zf-C3HC4 PF00097.25 KIK70561.1 - 5.1e-09 35.9 9.9 8.4e-09 35.2 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70561.1 - 1e-07 32.2 10.7 1.7e-07 31.5 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK70561.1 - 1.1e-07 31.8 10.6 1.4e-07 31.4 7.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK70561.1 - 2.1e-07 30.7 8.7 1.2e-06 28.2 9.4 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK70561.1 - 4e-07 29.8 5.8 6e-07 29.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK70561.1 - 8.4e-06 25.8 10.4 1.4e-05 25.1 10.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIK70561.1 - 1.8e-05 24.6 8.4 3.3e-05 23.8 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK70561.1 - 0.0009 19.1 7.6 0.0023 17.8 7.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIK70561.1 - 0.0082 16.2 4.0 0.014 15.4 4.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK70561.1 - 0.015 15.5 8.6 0.03 14.6 8.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KIK70561.1 - 0.028 14.2 7.9 0.055 13.3 7.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 KIK70561.1 - 0.15 12.2 2.3 0.27 11.3 2.3 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-MIZ PF02891.20 KIK70561.1 - 0.34 10.7 9.3 0.68 9.7 9.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 KIK70561.1 - 0.9 9.3 11.2 2.2 8.1 5.8 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 KIK70561.1 - 2.1 8.5 4.3 4.3 7.6 4.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Wbp11 PF09429.10 KIK70562.1 - 7.4e-20 71.1 10.6 7.4e-20 71.1 10.6 2.0 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.7 KIK70562.1 - 5.6e-15 55.8 4.7 5.6e-15 55.8 4.7 5.3 5 1 0 5 5 5 1 mRNA biogenesis factor Colicin_Pyocin PF01320.18 KIK70562.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein APG6_N PF17675.1 KIK70562.1 - 5.2 7.6 15.2 0.8 10.2 9.7 2.1 3 0 0 3 3 3 0 Apg6 coiled-coil region F-box-like PF12937.7 KIK70563.1 - 2.7e-09 36.8 0.0 9.4e-09 35.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK70563.1 - 5.7e-05 22.9 0.0 0.0002 21.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain PhzC-PhzF PF02567.16 KIK70564.1 - 1.7e-38 132.7 0.1 2e-38 132.5 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein FAD_binding_3 PF01494.19 KIK70566.1 - 1.6e-23 83.6 0.0 1.2e-22 80.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KIK70566.1 - 2.8e-05 23.6 0.1 0.026 13.8 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK70566.1 - 4.2e-05 23.7 0.9 0.00011 22.3 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK70566.1 - 0.00087 18.2 0.2 0.08 11.8 0.1 2.8 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KIK70566.1 - 0.00099 18.8 3.0 0.0019 17.8 3.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK70566.1 - 0.0015 17.9 1.0 0.0036 16.6 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK70566.1 - 0.0047 16.1 4.3 0.0066 15.6 4.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK70566.1 - 0.0058 15.9 1.7 0.0087 15.3 0.9 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KIK70566.1 - 0.0083 16.7 0.8 0.016 15.7 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK70566.1 - 0.028 13.8 0.7 0.04 13.3 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 KIK70566.1 - 0.063 12.3 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KIK70566.1 - 0.066 12.4 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK70566.1 - 0.085 11.9 2.8 0.13 11.3 2.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIK70566.1 - 0.13 12.1 0.6 0.21 11.4 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIK70566.1 - 0.17 10.6 0.5 0.26 10.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK70566.1 - 0.19 11.7 0.6 4 7.4 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding HIT PF01230.23 KIK70567.1 - 5.7e-21 75.1 0.0 7.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK70567.1 - 2.8e-06 27.8 0.0 4.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ribonuclease_T2 PF00445.18 KIK70568.1 - 1e-35 123.6 0.0 1.9e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family RRN3 PF05327.11 KIK70571.1 - 0.00035 19.3 6.0 0.00039 19.1 6.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KIK70571.1 - 0.005 16.3 12.3 0.0072 15.8 12.3 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 KIK70571.1 - 0.025 12.9 13.1 0.035 12.4 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 KIK70571.1 - 0.034 14.3 1.1 0.053 13.7 1.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 KIK70571.1 - 0.15 11.1 1.8 0.21 10.5 1.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 KIK70571.1 - 0.32 11.3 12.5 0.62 10.4 12.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 KIK70571.1 - 0.44 11.0 5.7 0.8 10.1 5.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 KIK70571.1 - 0.99 9.3 10.5 1.8 8.5 10.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 KIK70571.1 - 3 7.6 9.9 4.7 6.9 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GCIP PF13324.6 KIK70571.1 - 7.8 6.0 13.6 2.1e+02 1.4 13.6 2.3 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Hydrolase_4 PF12146.8 KIK70573.1 - 0.032 13.5 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 F-box-like PF12937.7 KIK70575.1 - 1.9e-08 34.1 2.0 6e-08 32.4 2.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK70575.1 - 0.00022 21.0 2.9 0.15 12.0 0.3 2.9 2 0 0 2 2 2 2 F-box domain Metallophos PF00149.28 KIK70576.1 - 2.4e-12 47.8 0.4 4.5e-12 46.9 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK70576.1 - 0.034 14.4 0.0 0.42 10.8 0.0 2.5 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain RSN1_7TM PF02714.15 KIK70577.1 - 6.2e-13 48.7 17.3 1.5e-12 47.4 17.3 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KIK70577.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK70577.1 - 0.00028 20.7 0.1 0.00028 20.7 0.1 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport AAA PF00004.29 KIK70579.1 - 4.7e-48 162.9 0.0 1.2e-41 142.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK70579.1 - 4.9e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KIK70579.1 - 1.4e-08 34.7 0.0 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 KIK70579.1 - 8.2e-08 32.8 0.2 5.4e-05 23.6 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KIK70579.1 - 5.8e-06 26.5 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK70579.1 - 5.9e-05 23.4 1.5 0.13 12.6 0.2 4.2 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KIK70579.1 - 7.4e-05 22.8 0.0 0.0031 17.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 KIK70579.1 - 0.00053 20.0 0.2 0.0019 18.2 0.2 1.9 1 0 0 1 1 1 1 Bromodomain AAA_33 PF13671.6 KIK70579.1 - 0.00064 19.9 0.7 0.032 14.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 KIK70579.1 - 0.0077 15.8 0.0 0.61 9.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KIK70579.1 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KIK70579.1 - 0.021 14.9 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIK70579.1 - 0.021 15.2 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KIK70579.1 - 0.022 15.3 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KIK70579.1 - 0.031 13.8 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIK70579.1 - 0.04 13.3 1.1 0.14 11.5 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KIK70579.1 - 0.04 13.9 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KIK70579.1 - 0.046 13.5 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KIK70579.1 - 0.057 13.6 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK70579.1 - 0.064 12.7 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KIK70579.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK70579.1 - 0.082 13.4 0.0 0.3 11.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KIK70579.1 - 0.085 12.6 0.0 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.13 KIK70579.1 - 0.09 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AFG1_ATPase PF03969.16 KIK70579.1 - 0.097 11.5 0.0 0.69 8.7 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase NACHT PF05729.12 KIK70579.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KIK70579.1 - 0.14 12.2 0.0 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 KIK70579.1 - 0.18 11.9 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Torsin PIF1 PF05970.14 KIK70579.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Parvo_NS1 PF01057.17 KIK70579.1 - 0.21 10.7 0.0 0.47 9.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KIK70579.1 - 0.81 9.4 0.0 0.81 9.4 0.0 3.2 4 0 0 4 4 4 0 AAA domain Zn_clus PF00172.18 KIK70580.1 - 0.00014 21.9 7.6 0.00029 20.9 7.6 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK70580.1 - 0.00099 18.2 0.1 0.0015 17.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec1 PF00995.23 KIK70581.1 - 1.7e-123 413.9 0.0 2.1e-123 413.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 KIK70581.1 - 0.24 11.3 0.8 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Qua1 domain Aminotran_1_2 PF00155.21 KIK70582.1 - 5.6e-14 52.1 0.0 1.9e-12 47.0 0.0 2.7 1 1 0 1 1 1 1 Aminotransferase class I and II Ribosomal_60s PF00428.19 KIK70584.1 - 5.2e-27 94.3 7.5 6.8e-27 93.9 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KIK70584.1 - 0.17 10.3 1.3 0.21 10.0 1.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein WD40 PF00400.32 KIK70585.1 - 1.7e-34 117.2 19.0 1.2e-06 29.1 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70585.1 - 4.3e-16 59.0 0.2 2.1e-05 24.7 0.0 5.6 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KIK70585.1 - 3.4e-08 33.2 0.1 7.2e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 KIK70585.1 - 0.00023 20.6 0.0 0.27 10.5 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KIK70585.1 - 0.00097 18.2 0.1 2.3 7.1 0.0 3.5 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK70585.1 - 0.0012 18.7 1.8 1.1 9.2 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK70585.1 - 0.0025 17.2 0.2 2.2 7.6 0.0 3.3 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK70585.1 - 0.0036 17.2 0.0 0.066 13.1 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK70585.1 - 0.07 11.6 0.0 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_3 PF15911.5 KIK70585.1 - 0.099 12.7 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat WD40 PF00400.32 KIK70586.1 - 1.3e-13 51.2 20.0 0.022 15.6 1.7 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KIK70586.1 - 0.25 10.0 2.3 1.7 7.2 0.0 3.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Bax1-I PF01027.20 KIK70587.1 - 5.1e-38 131.0 7.5 5.1e-38 131.0 7.5 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 AAA PF00004.29 KIK70588.1 - 3.4e-91 302.5 0.0 3.1e-46 157.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK70588.1 - 9.7e-22 76.5 0.7 9.3e-10 38.2 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KIK70588.1 - 6e-16 58.6 0.0 2.2e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK70588.1 - 1.5e-12 48.3 1.3 0.00025 21.5 0.1 4.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK70588.1 - 1.3e-11 44.9 0.5 0.0093 16.2 0.1 5.1 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.14 KIK70588.1 - 5.7e-11 42.6 0.3 0.00061 19.8 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIK70588.1 - 1.9e-10 41.1 0.0 8.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KIK70588.1 - 2.5e-10 40.8 0.0 0.00074 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KIK70588.1 - 6.8e-09 35.4 0.0 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KIK70588.1 - 1.3e-08 34.5 0.2 0.0069 15.8 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KIK70588.1 - 3e-08 33.8 0.0 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KIK70588.1 - 1.1e-07 32.2 0.0 0.024 15.0 0.0 2.9 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KIK70588.1 - 1.2e-07 31.6 0.0 0.02 14.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KIK70588.1 - 6.5e-07 29.7 0.0 0.015 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KIK70588.1 - 1.5e-06 28.1 0.0 0.0062 16.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIK70588.1 - 2e-06 28.3 0.0 0.11 13.0 0.0 3.3 3 1 0 3 3 2 2 ABC transporter TsaE PF02367.17 KIK70588.1 - 4.8e-06 26.6 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIK70588.1 - 7.1e-06 26.0 0.8 0.056 13.4 0.0 3.3 3 1 0 3 3 2 2 NACHT domain AAA_25 PF13481.6 KIK70588.1 - 9.6e-06 25.3 3.4 0.52 9.9 0.0 4.2 3 1 1 4 4 4 2 AAA domain ATPase PF06745.13 KIK70588.1 - 1.2e-05 24.8 0.1 0.72 9.1 0.0 3.2 2 1 0 3 3 3 2 KaiC Rad17 PF03215.15 KIK70588.1 - 2e-05 24.6 0.0 0.066 13.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 KIK70588.1 - 2.5e-05 24.8 0.0 0.35 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 KIK70588.1 - 3.2e-05 24.2 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Zeta_toxin PF06414.12 KIK70588.1 - 4.3e-05 22.9 0.0 0.35 10.1 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin Sigma54_activat PF00158.26 KIK70588.1 - 4.5e-05 23.2 0.0 0.46 10.2 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 KIK70588.1 - 9.9e-05 22.8 0.0 0.16 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KIK70588.1 - 0.00014 21.1 0.0 0.0056 15.9 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIK70588.1 - 0.00017 21.2 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KIK70588.1 - 0.00047 19.9 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 KIK70588.1 - 0.00088 19.4 0.0 0.96 9.6 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase NB-ARC PF00931.22 KIK70588.1 - 0.001 18.3 0.0 0.92 8.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.18 KIK70588.1 - 0.0013 18.5 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KIK70588.1 - 0.0013 18.5 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 KIK70588.1 - 0.0015 18.7 0.0 3.1 7.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 KIK70588.1 - 0.0018 17.7 0.3 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 KIK70588.1 - 0.002 17.3 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KIK70588.1 - 0.0023 17.9 0.0 2 8.3 0.0 3.1 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 KIK70588.1 - 0.0046 16.4 0.0 12 5.3 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 KIK70588.1 - 0.0047 16.9 0.4 4 7.5 0.0 3.3 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain Hydin_ADK PF17213.3 KIK70588.1 - 0.005 17.1 2.9 2.6 8.3 0.0 4.0 4 0 0 4 4 4 1 Hydin Adenylate kinase-like domain AFG1_ATPase PF03969.16 KIK70588.1 - 0.0071 15.3 0.0 0.45 9.3 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase Bac_DnaA PF00308.18 KIK70588.1 - 0.035 13.9 0.0 4.8 6.9 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 KIK70588.1 - 0.037 14.4 1.0 14 6.0 0.2 3.0 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIK70588.1 - 0.044 13.5 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KIK70588.1 - 0.046 13.6 0.1 6.9 6.5 0.0 2.7 3 0 0 3 3 2 0 NTPase CPT PF07931.12 KIK70588.1 - 0.056 13.3 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 KIK70588.1 - 0.066 12.9 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase DUF2075 PF09848.9 KIK70588.1 - 0.076 12.2 0.0 6.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L30 PF00327.20 KIK70589.1 - 5.4e-11 42.2 0.4 1e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e GFRP PF06399.13 KIK70589.1 - 0.064 13.2 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Arginase PF00491.21 KIK70590.1 - 2.4e-88 296.3 0.0 2.9e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family SUR7 PF06687.12 KIK70593.1 - 9.5e-19 67.9 19.3 1.3e-18 67.4 19.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Sin3a_C PF16879.5 KIK70594.1 - 3.7e-80 269.7 0.8 9.8e-79 265.0 0.0 3.0 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KIK70594.1 - 1.5e-41 140.3 11.7 1.1e-18 67.1 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KIK70594.1 - 4.2e-36 123.0 0.1 9.7e-36 121.8 0.1 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor HemY_N PF07219.13 KIK70595.1 - 0.42 10.8 1.8 0.8 9.9 0.4 2.2 2 1 1 3 3 3 0 HemY protein N-terminus DUF5549 PF17703.1 KIK70596.1 - 0.0047 16.6 0.2 0.0085 15.8 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5549) Xpo1 PF08389.12 KIK70596.1 - 0.0078 16.3 1.1 0.59 10.2 0.5 2.7 2 0 0 2 2 2 1 Exportin 1-like protein Arm PF00514.23 KIK70596.1 - 0.009 16.0 2.0 0.061 13.4 0.0 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK70596.1 - 0.042 14.4 7.2 0.094 13.2 0.1 4.4 4 1 1 5 5 5 0 HEAT-like repeat DUF3636 PF12331.8 KIK70596.1 - 0.052 13.4 5.3 1.5 8.6 0.0 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF3636) KAP PF05804.12 KIK70596.1 - 0.17 10.0 0.0 0.28 9.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) HEAT PF02985.22 KIK70596.1 - 3.6 8.1 7.3 14 6.3 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Ribonuc_L-PSP PF01042.21 KIK70597.1 - 7.8e-29 100.1 0.0 8.6e-29 100.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_2 PF03446.15 KIK70599.1 - 4.9e-19 69.1 0.0 8.1e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIK70599.1 - 6.1e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KIK70599.1 - 6e-05 23.1 0.0 0.00071 19.7 0.0 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIK70599.1 - 0.00013 22.5 0.0 0.00024 21.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 KIK70600.1 - 4.3e-41 141.0 0.0 6.2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70600.1 - 8.6e-32 110.4 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK70600.1 - 8.7e-05 21.6 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK70600.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ctr PF04145.15 KIK70601.1 - 2.1e-05 25.2 12.1 0.0075 16.9 0.9 2.3 1 1 1 2 2 2 2 Ctr copper transporter family Exo5 PF09810.9 KIK70602.1 - 4.7e-74 250.1 0.2 7.3e-71 239.6 0.2 2.7 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KIK70602.1 - 0.058 13.3 0.0 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily N_BRCA1_IG PF16158.5 KIK70603.1 - 5.1e-28 97.8 0.0 1.3e-27 96.5 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KIK70603.1 - 4e-22 77.8 50.1 5e-09 35.8 8.6 4.5 4 0 0 4 4 4 3 Zinc finger, ZZ type C1_2 PF03107.16 KIK70603.1 - 0.00028 21.1 52.0 0.0022 18.3 5.9 4.5 4 0 0 4 4 4 3 C1 domain Exo_endo_phos PF03372.23 KIK70604.1 - 3.3e-21 75.9 0.0 4.8e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3099 PF11298.8 KIK70604.1 - 0.1 12.7 1.0 0.2 11.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Abhydrolase_3 PF07859.13 KIK70605.1 - 5.6e-47 160.3 0.0 8e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK70605.1 - 2.4e-15 56.3 0.0 9.1e-15 54.4 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK70605.1 - 0.0014 17.6 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 KIK70605.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_M24 PF00557.24 KIK70606.1 - 4.4e-40 137.6 0.1 5.5e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Coilin_N PF15862.5 KIK70606.1 - 0.71 9.7 4.0 17 5.2 3.8 2.3 2 0 0 2 2 2 0 Coilin N-terminus NTF2 PF02136.20 KIK70607.1 - 9.6e-14 52.0 0.0 3.9e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KIK70607.1 - 5.2e-08 33.0 0.0 6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 HA2 PF04408.23 KIK70608.1 - 4e-24 85.0 0.0 1.3e-23 83.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK70608.1 - 4.5e-24 84.6 0.0 8.8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK70608.1 - 5.9e-14 52.4 0.0 3.3e-13 49.9 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KIK70608.1 - 2.9e-06 27.5 0.1 6.9e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KIK70608.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KIK70608.1 - 0.00065 20.2 0.9 0.28 11.7 0.1 3.1 2 1 0 2 2 2 1 ABC transporter T2SSE PF00437.20 KIK70608.1 - 0.0017 17.5 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KIK70608.1 - 0.0018 18.5 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK70608.1 - 0.0044 16.3 0.0 0.0098 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIK70608.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK70608.1 - 0.015 14.8 0.1 0.44 10.0 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KIK70608.1 - 0.034 14.5 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KIK70608.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain HA2 PF04408.23 KIK70609.1 - 2.9e-19 69.4 0.1 1.5e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK70609.1 - 1.6e-14 54.0 0.0 4.2e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK70609.1 - 4.7e-12 46.2 0.5 1.4e-11 44.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK70609.1 - 2.1e-10 40.6 0.0 4.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK70609.1 - 2.6e-05 24.5 1.0 0.00076 19.8 0.2 2.9 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 KIK70609.1 - 0.0058 16.6 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK70609.1 - 0.0086 16.4 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KIK70609.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIK70609.1 - 0.12 12.8 0.4 0.99 9.8 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KIK70609.1 - 0.14 11.4 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KIK70609.1 - 0.19 11.8 0.1 1.8 8.6 0.1 2.6 1 1 0 1 1 1 0 AAA domain UPF0242 PF06785.11 KIK70610.1 - 0.13 12.3 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran PF00005.27 KIK70611.1 - 4.9e-47 159.9 0.1 1.2e-25 90.7 0.3 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK70611.1 - 2.5e-43 148.7 31.3 2.2e-29 103.0 5.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK70611.1 - 4.1e-08 32.9 6.7 0.0033 16.9 2.4 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KIK70611.1 - 1.4e-06 27.5 0.2 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KIK70611.1 - 2.1e-06 27.4 0.6 0.05 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KIK70611.1 - 7.2e-05 23.0 3.7 0.0038 17.3 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KIK70611.1 - 7.5e-05 23.2 3.3 0.72 10.2 1.8 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KIK70611.1 - 0.0002 21.0 1.1 0.23 11.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIK70611.1 - 0.00039 21.0 0.2 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIK70611.1 - 0.00046 19.5 0.7 0.073 12.3 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 KIK70611.1 - 0.002 17.9 0.1 0.098 12.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KIK70611.1 - 0.0028 17.7 0.2 0.7 10.0 0.0 3.2 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KIK70611.1 - 0.0029 16.9 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 KIK70611.1 - 0.0032 17.6 0.1 0.62 10.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK70611.1 - 0.005 17.1 1.7 1.4 9.2 0.5 3.2 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KIK70611.1 - 0.0063 15.5 0.9 0.087 11.7 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 KIK70611.1 - 0.011 15.7 0.5 0.7 9.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KIK70611.1 - 0.016 15.1 4.1 0.88 9.5 0.1 3.3 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KIK70611.1 - 0.035 13.9 0.3 12 5.6 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KIK70611.1 - 0.055 13.5 0.3 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 KIK70611.1 - 0.058 13.0 1.3 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KIK70611.1 - 0.066 12.4 0.1 2.1 7.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KIK70611.1 - 0.093 12.1 2.1 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KIK70611.1 - 0.12 12.1 0.1 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KIK70611.1 - 0.16 11.4 0.2 22 4.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK70611.1 - 0.17 12.3 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KIK70611.1 - 0.2 12.2 0.1 8.8 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIK70611.1 - 1.2 8.9 5.7 56 3.4 0.1 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIK70611.1 - 2.9 8.2 4.0 24 5.3 0.1 3.6 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF89 PF01937.19 KIK70612.1 - 1.6e-106 356.2 0.0 2e-106 355.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 HEPN_Apea PF18739.1 KIK70612.1 - 0.1 13.0 0.1 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Apea-like HEPN NDUFV3 PF15880.5 KIK70612.1 - 0.17 11.9 0.1 0.77 9.8 0.1 2.1 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Mce4_CUP1 PF11887.8 KIK70613.1 - 0.024 14.1 3.1 0.038 13.4 3.1 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DNA_photolyase PF00875.18 KIK70613.1 - 0.026 14.5 1.7 0.069 13.2 0.0 2.2 1 1 1 2 2 2 0 DNA photolyase FlaC_arch PF05377.11 KIK70613.1 - 0.035 14.5 10.5 7.1 7.1 0.1 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KIK70613.1 - 0.043 14.1 0.8 0.043 14.1 0.8 4.1 2 1 2 4 4 4 0 ABC transporter C-terminal domain FAM76 PF16046.5 KIK70613.1 - 0.074 12.4 20.4 0.64 9.3 3.6 2.6 1 1 2 3 3 3 0 FAM76 protein Tropomyosin_1 PF12718.7 KIK70613.1 - 0.082 13.1 25.6 0.14 12.3 16.7 2.5 1 1 0 2 2 2 0 Tropomyosin like NAPRTase_C PF17956.1 KIK70613.1 - 0.16 12.4 5.1 0.3 11.5 0.1 2.8 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF1664 PF07889.12 KIK70613.1 - 0.17 11.9 16.6 0.085 12.9 2.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KIK70613.1 - 0.55 10.7 21.5 33 4.9 21.5 2.2 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 KIK70613.1 - 0.58 9.0 28.3 1.2 7.9 20.3 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 KIK70613.1 - 0.95 9.9 21.1 0.6 10.5 12.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 KIK70613.1 - 1.1 8.7 25.7 0.66 9.4 4.1 3.0 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal LON_substr_bdg PF02190.16 KIK70613.1 - 1.5 8.7 8.9 0.4 10.5 4.1 1.9 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain KASH_CCD PF14662.6 KIK70613.1 - 2.2 8.1 25.6 9.2 6.0 18.6 2.9 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ALMT PF11744.8 KIK70613.1 - 3.2 6.5 11.5 3.9 6.2 11.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3584 PF12128.8 KIK70613.1 - 4.1 4.8 22.8 1.2 6.6 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Plk4_PB2 PF18409.1 KIK70613.1 - 5.3 7.8 8.1 2.1 9.1 0.5 2.6 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 APG6_N PF17675.1 KIK70613.1 - 5.3 7.6 30.4 14 6.2 1.3 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region Laminin_II PF06009.12 KIK70613.1 - 6.1 6.9 18.8 1 9.4 10.7 2.8 2 1 0 2 2 2 0 Laminin Domain II MetOD2 PF18548.1 KIK70613.1 - 8.3 6.6 12.9 2.5 8.3 0.4 3.4 3 1 1 4 4 3 0 Metanogen output domain 2 GAS PF13851.6 KIK70614.1 - 0.0027 17.1 5.9 0.0027 17.1 5.9 3.0 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 KIK70614.1 - 0.01 16.6 9.1 0.45 11.3 0.2 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) tRNA_bind_3 PF17176.4 KIK70614.1 - 0.011 16.0 3.7 0.021 15.1 0.8 2.5 2 0 0 2 2 2 0 tRNA-binding domain HSBP1 PF06825.12 KIK70614.1 - 0.051 13.4 2.6 0.42 10.5 1.2 3.2 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF1664 PF07889.12 KIK70614.1 - 0.21 11.6 8.6 0.89 9.6 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 KIK70614.1 - 0.67 9.7 9.5 1.8 8.2 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) zf-C4H2 PF10146.9 KIK70614.1 - 0.8 10.0 12.2 2.7 8.3 7.8 2.9 2 1 0 2 2 2 0 Zinc finger-containing protein DUF1843 PF08898.10 KIK70614.1 - 0.84 10.2 3.9 25 5.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) ADIP PF11559.8 KIK70614.1 - 0.9 9.6 22.8 5.2 7.1 0.7 3.4 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KIK70614.1 - 1.3 8.0 14.5 0.23 10.5 7.8 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phlebovirus_NSM PF07246.11 KIK70614.1 - 1.9 7.8 8.9 0.62 9.4 1.4 2.4 2 1 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 KIK70614.1 - 3.8 6.8 14.8 28 3.9 14.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PAXX PF15384.6 KIK70615.1 - 0.034 13.9 0.5 0.039 13.6 0.5 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 TPR_MLP1_2 PF07926.12 KIK70615.1 - 0.044 13.8 16.1 0.52 10.4 12.9 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4795 PF16043.5 KIK70615.1 - 0.14 11.8 9.3 0.19 11.3 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 KIK70615.1 - 0.14 12.1 15.5 2.6 8.1 7.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HlyD_2 PF12700.7 KIK70615.1 - 0.15 10.8 5.3 0.15 10.8 5.3 1.0 1 0 0 1 1 1 0 HlyD family secretion protein TMF_TATA_bd PF12325.8 KIK70615.1 - 0.15 12.3 15.6 0.43 10.8 15.6 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SesA PF17107.5 KIK70615.1 - 0.16 12.2 3.3 0.61 10.3 3.3 1.8 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases IFT57 PF10498.9 KIK70615.1 - 0.21 10.5 10.4 0.24 10.3 10.4 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ECH_2 PF16113.5 KIK70615.1 - 0.23 10.9 6.1 0.25 10.8 6.1 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase CdvA PF18822.1 KIK70615.1 - 0.24 11.2 11.3 6.4 6.6 6.6 2.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DAGK_cat PF00781.24 KIK70615.1 - 0.28 10.8 1.1 0.44 10.2 1.1 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF1664 PF07889.12 KIK70615.1 - 0.31 11.1 3.8 4.7 7.3 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 KIK70615.1 - 0.48 10.9 11.5 1 9.8 11.5 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 KIK70615.1 - 0.56 11.1 12.7 0.78 10.7 12.7 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain PCRF PF03462.18 KIK70615.1 - 0.67 9.8 7.3 0.81 9.5 7.3 1.2 1 0 0 1 1 1 0 PCRF domain zf-C4pol PF14260.6 KIK70615.1 - 0.73 10.3 3.5 1.4 9.5 0.4 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FlaC_arch PF05377.11 KIK70615.1 - 0.73 10.3 11.1 1.7 9.1 0.1 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Ly49 PF08391.10 KIK70615.1 - 0.8 10.1 8.4 0.36 11.2 2.7 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region GPHR_N PF12537.8 KIK70615.1 - 1 9.5 3.4 13 6.0 0.6 2.4 1 1 1 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Csm1_N PF18504.1 KIK70615.1 - 1.1 9.7 14.1 5.1 7.5 0.4 3.0 1 1 1 2 2 2 0 Csm1 N-terminal domain FmiP_Thoc5 PF09766.9 KIK70615.1 - 1.2 8.3 14.4 0.52 9.5 3.9 2.0 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 FapA PF03961.13 KIK70615.1 - 1.5 7.3 8.7 1.8 7.0 8.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KIK70615.1 - 1.7 7.9 5.4 2.1 7.6 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KIK70615.1 - 3.4 6.8 8.0 4.1 6.6 8.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 KIK70615.1 - 3.6 7.1 7.2 4 6.9 7.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit NYD-SP28_assoc PF14775.6 KIK70615.1 - 4.1 7.6 10.3 1.1 9.5 4.5 2.4 1 1 0 2 2 2 0 Sperm tail C-terminal domain DUF4140 PF13600.6 KIK70615.1 - 4.3 7.8 8.0 1.9 8.9 0.4 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 KIK70615.1 - 5.2 7.3 10.4 4 7.7 4.6 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Swi5 PF07061.11 KIK70615.1 - 7.9 6.6 12.3 12 6.0 2.8 2.4 1 1 2 3 3 3 0 Swi5 HNOBA PF07701.14 KIK70615.1 - 9.4 5.6 8.9 0.94 8.9 1.4 2.1 1 1 1 2 2 2 0 Heme NO binding associated CLZ PF16526.5 KIK70616.1 - 0.0032 17.8 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4094 PF13334.6 KIK70616.1 - 0.012 16.0 0.1 0.026 14.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Cnn_1N PF07989.11 KIK70616.1 - 0.023 14.9 0.2 0.035 14.3 0.2 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 KIK70616.1 - 0.032 14.6 0.4 0.06 13.7 0.4 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF3138 PF11336.8 KIK70616.1 - 0.1 11.2 0.3 0.13 10.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Lgl_C PF08596.10 KIK70617.1 - 1.3e-44 152.6 0.0 2.6e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KIK70617.1 - 0.00025 21.3 0.0 1.3 9.3 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 KIK70617.1 - 1.9 8.3 3.9 1.3 8.9 0.2 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF2358 PF10184.9 KIK70618.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KIK70618.1 - 0.0016 19.0 0.0 0.0027 18.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain V-SNARE_C PF12352.8 KIK70619.1 - 1.2e-14 54.3 3.1 1.2e-14 54.3 3.1 3.1 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Med30 PF11315.8 KIK70619.1 - 0.0061 16.8 1.4 0.0083 16.3 0.2 1.8 2 1 0 2 2 2 1 Mediator complex subunit 30 Sec8_exocyst PF04048.14 KIK70619.1 - 0.012 15.6 2.3 4.3 7.2 0.0 2.8 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain APG6_N PF17675.1 KIK70619.1 - 0.017 15.7 4.8 0.017 15.7 4.8 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 KIK70619.1 - 0.019 15.0 3.1 0.44 10.6 0.4 2.9 2 1 1 3 3 3 0 Laminin Domain II kleA_kleC PF17383.2 KIK70619.1 - 0.092 13.1 1.3 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A CCDC-167 PF15188.6 KIK70619.1 - 0.12 12.8 3.4 3.3 8.1 2.3 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Sec20 PF03908.13 KIK70619.1 - 0.17 11.8 1.3 0.42 10.6 0.0 2.2 3 1 0 3 3 3 0 Sec20 V_ATPase_I PF01496.19 KIK70619.1 - 0.17 9.8 1.2 0.19 9.6 1.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KIK70619.1 - 0.31 10.3 0.6 0.54 9.5 0.3 1.5 1 1 0 1 1 1 0 TMPIT-like protein Baculo_PEP_C PF04513.12 KIK70619.1 - 0.37 10.8 5.3 0.29 11.2 1.1 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 KIK70619.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.4 2 0 0 2 2 1 0 Haemolysin XhlA CK2S PF15011.6 KIK70619.1 - 0.54 10.1 5.3 3.1 7.7 4.1 2.7 1 1 1 2 2 2 0 Casein Kinase 2 substrate TatD_DNase PF01026.21 KIK70620.1 - 4.6e-25 88.5 0.0 6.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Myb_DNA-bind_6 PF13921.6 KIK70620.1 - 0.034 14.4 1.5 0.14 12.5 0.1 2.5 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK70620.1 - 0.046 13.9 1.5 0.086 13.1 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Met_10 PF02475.16 KIK70621.1 - 2.3e-70 236.4 0.0 2.9e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KIK70621.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 KIK70621.1 - 0.0019 17.8 0.0 0.0044 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 KIK70621.1 - 0.042 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase SUKH-4 PF14435.6 KIK70621.1 - 0.063 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 SUKH-4 immunity protein Cons_hypoth95 PF03602.15 KIK70621.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Mito_carr PF00153.27 KIK70622.1 - 1e-64 214.4 0.5 4e-25 87.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KIK70622.1 - 2.1e-18 66.5 5.7 1.1e-07 32.2 0.5 4.5 3 3 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KIK70622.1 - 1.6e-17 61.7 8.9 1.3e-07 30.7 1.3 5.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KIK70622.1 - 2.4e-16 58.2 8.2 4.2e-06 26.3 0.4 5.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 KIK70622.1 - 1.5e-12 47.1 7.0 0.00022 21.0 0.0 4.9 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 KIK70622.1 - 3.7e-09 35.7 11.4 3.7e-05 23.0 1.3 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 KIK70622.1 - 0.0052 16.7 1.2 7.1 6.6 0.6 3.4 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF953 PF06110.11 KIK70624.1 - 2.2e-11 43.4 0.1 1.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KIK70624.1 - 0.085 12.8 0.2 1.3 9.1 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin MoaC PF01967.21 KIK70625.1 - 3.9e-49 166.2 1.4 7e-49 165.4 1.4 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KIK70625.1 - 2.2e-37 127.8 0.0 4.1e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KIK70625.1 - 7.4e-26 91.5 0.0 1.3e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KIK70625.1 - 2.9e-06 27.6 0.0 5.1e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIK70625.1 - 0.0091 16.1 0.0 0.08 13.1 0.0 2.5 3 0 0 3 3 3 1 4Fe-4S single cluster domain NIPSNAP PF07978.13 KIK70627.1 - 4.7e-29 100.6 0.4 5.5e-25 87.6 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Fungal_trans PF04082.18 KIK70628.1 - 3.9e-39 134.3 0.0 6e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK70628.1 - 8.7e-08 32.2 6.9 1.5e-07 31.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Forkhead PF00250.18 KIK70629.1 - 1.6e-19 69.9 0.0 3.8e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Forkhead domain Herpes_capsid PF06112.11 KIK70629.1 - 0.023 14.7 2.0 0.046 13.8 2.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein WD40 PF00400.32 KIK70630.1 - 1.6e-54 180.6 22.6 1e-05 26.2 0.3 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KIK70630.1 - 5.4e-48 162.5 0.0 8.6e-48 161.9 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KIK70630.1 - 4.3e-08 33.3 4.7 3.4 8.0 0.0 7.4 5 2 3 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK70630.1 - 6.2e-06 25.7 0.9 0.00031 20.2 0.1 3.3 4 0 0 4 4 4 1 WD40-like domain VID27 PF08553.10 KIK70630.1 - 0.0014 17.8 0.1 0.015 14.4 0.0 2.5 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 KIK70630.1 - 0.015 13.8 0.0 0.12 10.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF5609 PF18429.1 KIK70630.1 - 0.13 12.0 0.1 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) FB_lectin PF07367.11 KIK70630.1 - 0.14 12.1 0.4 6.7 6.6 0.1 2.3 2 0 0 2 2 2 0 Fungal fruit body lectin Aminotran_4 PF01063.19 KIK70631.1 - 1.4e-29 103.6 0.0 1.8e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV RhoGEF PF00621.20 KIK70632.1 - 1.7e-11 44.7 0.0 9.3e-09 35.8 0.0 2.7 3 0 0 3 3 3 2 RhoGEF domain BAR PF03114.18 KIK70634.1 - 4.7e-44 150.8 11.1 6.8e-44 150.3 11.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIK70634.1 - 8.9e-13 47.6 0.1 1.8e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK70634.1 - 2.6e-10 40.0 1.3 5.3e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIK70634.1 - 3.4e-07 29.8 0.0 7.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Spc7 PF08317.11 KIK70634.1 - 0.017 14.0 12.6 0.031 13.2 12.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BAR_2 PF10455.9 KIK70634.1 - 0.067 12.3 7.8 0.038 13.1 5.2 1.9 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking V_ATPase_I PF01496.19 KIK70634.1 - 1.9 6.3 6.2 2.6 5.8 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KIK70634.1 - 2.2 6.8 6.3 3.6 6.1 6.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 KIK70634.1 - 2.4 8.7 17.4 6.7 7.2 17.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 KIK70634.1 - 4.5 6.4 5.3 8.5 5.5 5.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein NOA36 PF06524.12 KIK70635.1 - 5.2 6.3 7.2 3.6 6.8 3.7 2.1 2 0 0 2 2 2 0 NOA36 protein Lum_binding PF00677.17 KIK70636.1 - 4.2e-43 145.2 0.0 1.6e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Dioxygenase_C PF00775.21 KIK70638.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Tafi-CsgC PF10610.9 KIK70639.1 - 0.29 11.3 1.4 0.45 10.7 1.4 1.3 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein Myosin_head PF00063.21 KIK70640.1 - 2.2e-227 756.5 0.1 3.3e-227 756.0 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KIK70640.1 - 2.7e-48 164.2 0.0 4.7e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding UNC45-central PF11701.8 KIK70640.1 - 1.6e-23 83.4 5.2 3.3e-19 69.3 0.1 5.0 4 1 1 5 5 5 2 Myosin-binding striated muscle assembly central SH3_9 PF14604.6 KIK70640.1 - 1.2e-09 37.8 0.2 2.8e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK70640.1 - 1.4e-09 37.5 0.0 3.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK70640.1 - 3.3e-09 36.2 1.1 7.3e-09 35.1 1.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KIK70640.1 - 0.00088 19.5 1.3 0.0023 18.2 1.3 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_19 PF13245.6 KIK70640.1 - 0.016 15.5 0.8 3.6 7.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KIK70640.1 - 0.035 14.5 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIK70640.1 - 0.067 13.5 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KIK70640.1 - 0.1 12.1 1.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 KIK70640.1 - 0.14 12.1 0.2 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Gcd10p PF04189.13 KIK70641.1 - 5.3e-66 222.8 0.0 8.5e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family PXA PF02194.15 KIK70642.1 - 5.7e-46 156.8 0.2 2.7e-45 154.6 0.1 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KIK70642.1 - 8.9e-31 106.8 0.0 2.9e-30 105.1 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KIK70642.1 - 2.4e-19 69.4 0.0 7.4e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KIK70642.1 - 3.3e-09 37.0 0.0 8.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain IBD PF10416.9 KIK70642.1 - 0.025 14.6 0.3 0.07 13.1 0.3 1.7 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Isy1 PF06246.12 KIK70642.1 - 0.038 13.5 1.2 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Isy1-like splicing family Snf7 PF03357.21 KIK70642.1 - 0.049 13.2 6.3 0.11 12.1 6.3 1.5 1 0 0 1 1 1 0 Snf7 Mito_carr PF00153.27 KIK70643.1 - 3e-52 174.5 1.6 1.9e-18 66.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DPBB_1 PF03330.18 KIK70644.1 - 7.4e-09 35.8 0.1 1.5e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase BRCA-2_OB1 PF09103.10 KIK70645.1 - 1.3e-32 112.3 0.0 2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KIK70645.1 - 0.0043 16.7 0.7 0.0096 15.6 0.7 1.5 1 1 0 1 1 1 1 BRCA2, helical Titin_Z PF09042.11 KIK70646.1 - 1.2 9.2 4.2 2.3 8.2 4.2 1.4 1 0 0 1 1 1 0 Titin Z Taxilin PF09728.9 KIK70647.1 - 4e-16 59.1 40.3 1.2e-09 37.8 18.9 2.9 2 2 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KIK70647.1 - 1.4e-05 24.9 0.0 0.049 13.5 0.0 3.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like SpoOE-like PF09388.10 KIK70647.1 - 0.022 14.7 2.2 0.11 12.4 2.2 2.3 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein DUF222 PF02720.17 KIK70647.1 - 0.026 14.0 6.3 0.039 13.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF222) ubiquitin PF00240.23 KIK70647.1 - 0.11 12.3 0.9 5.3 6.9 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin family Exonuc_VII_L PF02601.15 KIK70647.1 - 0.21 11.1 18.4 0.62 9.6 1.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Bacillus_HBL PF05791.11 KIK70647.1 - 0.36 10.6 10.3 0.47 10.3 5.7 2.5 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 KIK70647.1 - 0.38 10.8 13.4 1.9 8.5 5.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KIK70647.1 - 0.6 8.6 12.4 0.17 10.4 1.8 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family PriA_C PF18074.1 KIK70647.1 - 0.76 10.6 7.4 0.31 11.9 0.3 3.5 2 2 1 3 3 3 0 Primosomal protein N C-terminal domain Fib_alpha PF08702.10 KIK70647.1 - 2 8.6 14.6 2.3 8.4 0.8 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KIK70647.1 - 2.2 7.5 19.0 0.14 11.4 8.4 2.3 2 0 0 2 2 2 0 TMPIT-like protein Lectin_N PF03954.14 KIK70647.1 - 2.3 8.0 10.2 4.9 6.9 2.1 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain IF-2B PF01008.17 KIK70647.1 - 3.2 6.9 7.8 0.68 9.1 2.3 2.1 2 0 0 2 2 2 0 Initiation factor 2 subunit family PMEI PF04043.15 KIK70647.1 - 6.3 7.1 8.1 1 9.7 3.7 1.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor FapA PF03961.13 KIK70647.1 - 8.7 4.8 24.8 2.7 6.5 2.5 2.5 2 1 0 2 2 2 0 Flagellar Assembly Protein A UDPGP PF01704.18 KIK70648.1 - 5.1e-46 157.1 0.0 6.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KIK70648.1 - 0.029 14.7 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Peptidase_M16 PF00675.20 KIK70649.1 - 1e-39 135.9 0.0 1.7e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK70649.1 - 5.5e-34 117.8 0.0 1.3e-33 116.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_S10 PF00450.22 KIK70650.1 - 1e-82 278.8 0.1 1.3e-82 278.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ceramidase PF05875.12 KIK70654.1 - 9.9e-64 215.3 4.5 1.1e-63 215.1 4.5 1.0 1 0 0 1 1 1 1 Ceramidase Lactonase PF10282.9 KIK70655.1 - 1.2e-51 176.1 0.0 1.4e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller EF_TS PF00889.19 KIK70656.1 - 9e-22 77.7 0.0 9.9e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor TS HOIP-UBA PF16678.5 KIK70656.1 - 0.054 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Gar1 PF04410.14 KIK70657.1 - 6e-36 123.5 0.2 9.2e-36 122.9 0.2 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ACT_7 PF13840.6 KIK70659.1 - 2.2e-18 65.8 0.0 3.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 ACT domain SAS4 PF15460.6 KIK70660.1 - 8.7e-06 25.8 4.6 2.1e-05 24.5 4.6 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHHC PF01529.20 KIK70662.1 - 8.8e-36 123.0 13.2 8.8e-36 123.0 13.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase SUIM_assoc PF16619.5 KIK70663.1 - 0.29 11.2 13.7 3.3 7.9 0.0 4.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_2 PF14608.6 KIK70663.1 - 0.5 10.9 2.0 0.89 10.1 2.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Bromodomain PF00439.25 KIK70664.1 - 1.1e-36 124.7 2.4 2.1e-18 66.2 0.2 2.4 2 0 0 2 2 2 2 Bromodomain CutC PF03932.14 KIK70665.1 - 7.3e-59 198.6 0.1 8.8e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 CutC family F-box PF00646.33 KIK70666.1 - 6.3e-08 32.3 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK70666.1 - 3.8e-07 29.9 0.1 7.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK70666.1 - 0.004 17.0 0.1 0.0095 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box RPEL PF02755.15 KIK70666.1 - 0.074 12.8 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 RPEL repeat DUF2293 PF10056.9 KIK70666.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Glyco_transf_22 PF03901.17 KIK70667.1 - 1.2e-77 261.9 21.9 2.5e-77 260.9 21.9 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KIK70667.1 - 0.0031 17.7 10.5 0.0031 17.7 10.5 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase FtsX PF02687.21 KIK70668.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.5 1 1 1 2 2 2 0 FtsX-like permease family Thioredoxin PF00085.20 KIK70670.1 - 6.8e-24 83.8 0.0 8.9e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK70670.1 - 1.7e-06 28.4 0.1 2.2e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK70670.1 - 3.6e-05 24.0 0.0 0.0026 18.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KIK70670.1 - 7.2e-05 22.6 0.0 9.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KIK70670.1 - 0.00028 20.8 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF2847 PF11009.8 KIK70670.1 - 0.00063 19.6 0.0 0.0086 16.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2847) OST3_OST6 PF04756.13 KIK70670.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIK70670.1 - 0.015 15.4 0.2 0.027 14.7 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KIK70670.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin Mce4_CUP1 PF11887.8 KIK70670.1 - 0.052 13.0 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative TraF PF13728.6 KIK70670.1 - 0.21 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein dsrm PF00035.26 KIK70671.1 - 2.3e-08 34.6 0.0 5.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KIK70671.1 - 7.1e-05 23.0 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like DUF1378 PF07125.11 KIK70671.1 - 0.00064 19.8 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1378) Ribonuclease_3 PF00636.26 KIK70671.1 - 0.0047 17.5 0.2 0.013 16.1 0.2 1.7 1 1 0 1 1 1 1 Ribonuclease III domain I-set PF07679.16 KIK70672.1 - 0.032 14.3 0.3 12 6.0 0.0 4.6 5 1 0 5 5 5 0 Immunoglobulin I-set domain Pyrophosphatase PF00719.19 KIK70673.1 - 7.5e-60 201.4 0.2 9.5e-60 201.0 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase GCP_C_terminal PF04130.13 KIK70674.1 - 9.1e-33 114.0 0.0 2.2e-32 112.7 0.0 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIK70674.1 - 2.6e-27 96.3 0.1 9.9e-26 91.1 0.1 2.4 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal RabGAP-TBC PF00566.18 KIK70675.1 - 1.9e-33 116.0 0.0 2.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain K_channel_TID PF07941.11 KIK70676.1 - 0.021 15.3 0.0 0.053 14.0 0.0 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TPT PF03151.16 KIK70677.1 - 7.9e-12 45.1 22.0 1.1e-11 44.6 22.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK70677.1 - 0.004 17.3 33.7 0.024 14.8 13.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF5381 PF17353.2 KIK70677.1 - 0.061 13.1 0.5 0.061 13.1 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Deltameth_res PF16020.5 KIK70677.1 - 1.7 8.5 3.9 11 5.9 0.0 3.5 4 0 0 4 4 4 0 Deltamethrin resistance O-FucT PF10250.9 KIK70678.1 - 4.1e-09 36.6 0.0 1.6e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MCU PF04678.13 KIK70678.1 - 0.034 14.3 1.2 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter JSRP PF15312.6 KIK70679.1 - 0.045 13.7 0.9 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein ApbA_C PF08546.11 KIK70680.1 - 1.1e-33 116.0 0.7 2e-33 115.3 0.7 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIK70680.1 - 3.3e-24 85.3 0.2 7.1e-24 84.2 0.2 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF4037 PF13228.6 KIK70680.1 - 0.16 12.8 0.0 1.4 9.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4037) Aldo_ket_red PF00248.21 KIK70681.1 - 8.3e-39 133.5 0.0 1.3e-38 132.9 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family PIG-L PF02585.17 KIK70682.1 - 7.2e-18 65.5 0.0 9.4e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.32 KIK70685.1 - 2.5e-17 62.9 15.9 0.042 14.7 0.1 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK70685.1 - 0.00021 21.5 0.2 2.2 8.7 0.0 5.1 4 3 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KIK70685.1 - 0.1 11.6 0.0 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.12 KIK70685.1 - 0.21 11.6 1.5 3.6 7.6 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Methyltransf_25 PF13649.6 KIK70686.1 - 5.2e-15 55.9 0.0 1.1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK70686.1 - 3.1e-12 47.0 0.0 6.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK70686.1 - 7.1e-11 42.2 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK70686.1 - 1.9e-08 34.2 0.0 3.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK70686.1 - 6.2e-08 33.3 0.0 1.3e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK70686.1 - 2.6e-07 30.2 0.0 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KIK70686.1 - 1.6e-06 27.6 0.1 2.2e-05 23.9 0.0 2.5 2 1 1 3 3 3 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KIK70686.1 - 3.9e-05 23.2 0.0 0.00087 18.8 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KIK70686.1 - 0.00078 19.6 0.0 0.0019 18.4 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KIK70686.1 - 0.0036 15.9 0.0 0.0067 15.0 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KIK70686.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MMR_HSR1 PF01926.23 KIK70687.1 - 2.9e-15 56.3 0.0 7.1e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK70687.1 - 9e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK70687.1 - 0.00026 20.9 0.0 0.00093 19.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK70687.1 - 0.015 15.4 5.3 0.018 15.1 0.2 2.8 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.16 KIK70687.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KIK70687.1 - 0.081 13.1 0.2 0.58 10.4 0.1 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK70687.1 - 0.14 12.6 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Lipase_GDSL_2 PF13472.6 KIK70688.1 - 2.2e-10 41.2 1.2 3e-10 40.8 1.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK70688.1 - 0.00039 20.4 2.7 0.0025 17.8 2.7 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nucleo_P87 PF07267.11 KIK70689.1 - 0.099 11.5 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Dynamin_N PF00350.23 KIK70689.1 - 0.099 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Dynamin family HicB-like_2 PF15970.5 KIK70689.1 - 0.17 12.1 0.5 24 5.1 0.1 2.4 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Vta1 PF04652.16 KIK70690.1 - 3.4e-48 163.3 2.3 3.4e-48 163.3 2.3 1.6 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KIK70690.1 - 1.4e-16 59.9 0.8 1.4e-16 59.9 0.8 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain Swi6_N PF18530.1 KIK70690.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Swi6 N-terminal domain DUF4692 PF15763.5 KIK70690.1 - 0.71 10.3 8.9 0.13 12.8 0.7 2.9 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) HSP20 PF00011.21 KIK70691.1 - 5.9e-05 23.1 0.0 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 1 Hsp20/alpha crystallin family NIF PF03031.18 KIK70692.1 - 3.9e-09 36.5 0.0 0.00025 20.9 0.0 2.6 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Arrestin_C PF02752.22 KIK70693.1 - 4.4e-11 43.4 0.0 2e-10 41.2 0.0 2.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain RNase_P_pop3 PF08228.11 KIK70694.1 - 4.8e-14 52.7 0.2 1.4e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 dCMP_cyt_deam_1 PF00383.23 KIK70695.1 - 4.8e-26 90.6 0.5 6.5e-26 90.2 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK70695.1 - 6.6e-12 45.3 0.0 9.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KIK70695.1 - 0.042 14.0 0.3 0.071 13.2 0.3 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 V-ATPase_H_N PF03224.14 KIK70696.1 - 0.025 13.9 0.1 0.46 9.7 0.0 2.6 2 0 0 2 2 2 0 V-ATPase subunit H RTP1_C1 PF10363.9 KIK70696.1 - 0.16 12.2 0.1 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Chorismate_bind PF00425.18 KIK70697.1 - 2e-72 243.9 0.0 3.4e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KIK70697.1 - 2e-32 112.5 0.0 2.8e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KIK70697.1 - 6.6e-13 49.1 0.0 2.4e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KIK70697.1 - 3.9e-06 26.8 0.3 3.6e-05 23.6 0.3 2.1 1 1 0 1 1 1 1 Peptidase C26 Glyco_transf_29 PF00777.18 KIK70698.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) YccV-like PF08755.11 KIK70699.1 - 1.1e-22 80.3 0.1 3.1e-22 78.9 0.0 1.7 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KIK70699.1 - 9.4e-10 38.3 0.0 2.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KIK70699.1 - 0.049 13.5 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like Nop52 PF05997.12 KIK70701.1 - 7.9e-73 244.8 0.1 1.4e-72 244.0 0.0 1.4 2 0 0 2 2 2 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KIK70701.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 KIK70701.1 - 0.099 12.8 0.1 0.74 9.9 0.0 2.4 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Transthyretin PF00576.21 KIK70702.1 - 1.9e-38 131.6 0.0 2.1e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 KIK70702.1 - 0.012 15.8 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain UQ_con PF00179.26 KIK70703.1 - 3.2e-40 137.0 0.1 4.1e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIK70703.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain DIOX_N PF14226.6 KIK70704.1 - 0.00015 22.5 0.0 0.0003 21.5 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK70704.1 - 0.0023 18.4 0.0 0.0043 17.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SET PF00856.28 KIK70705.1 - 1.2e-09 38.8 0.0 1.2e-09 38.8 0.0 2.1 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KIK70705.1 - 2.1e-08 34.5 17.8 2.1e-08 34.5 17.8 3.5 2 1 2 4 4 4 1 CXC domain DUF1741 PF08427.10 KIK70706.1 - 9.3e-30 104.0 0.6 1.7e-29 103.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) GDC-P PF02347.16 KIK70707.1 - 2.6e-180 599.9 0.0 7.6e-170 565.4 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KIK70707.1 - 2.3e-06 26.8 0.0 1.8e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK70707.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PPR_2 PF13041.6 KIK70708.1 - 2.1e-12 47.0 1.6 1.2 9.4 0.0 7.7 7 1 0 8 8 8 4 PPR repeat family PPR_3 PF13812.6 KIK70708.1 - 8.3e-05 22.6 0.1 6.3 7.0 0.0 5.5 6 1 1 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.20 KIK70708.1 - 0.002 18.3 2.4 6.3 7.3 0.0 5.2 6 0 0 6 6 6 2 PPR repeat SecE PF00584.20 KIK70709.1 - 4.7e-15 55.3 0.0 5.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Vps51 PF08700.11 KIK70711.1 - 7.6e-11 41.9 2.8 2.1e-10 40.5 0.6 2.9 3 0 0 3 3 3 1 Vps51/Vps67 Nnf1 PF03980.14 KIK70711.1 - 0.0096 16.3 1.3 1.2 9.6 0.0 3.6 3 0 0 3 3 3 1 Nnf1 DUF1751 PF08551.10 KIK70712.1 - 8.7e-24 84.0 4.4 2.1e-23 82.7 4.4 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KIK70712.1 - 0.013 15.5 7.4 0.037 14.0 7.4 1.8 1 1 0 1 1 1 0 Rhomboid family DUF1754 PF08555.10 KIK70713.1 - 8e-16 58.6 5.6 1.3e-15 57.9 5.6 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.6 KIK70713.1 - 0.035 13.4 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Host_attach PF10116.9 KIK70713.1 - 0.038 14.6 3.3 0.067 13.8 3.3 1.4 1 1 0 1 1 1 0 Protein required for attachment to host cells Cucumo_2B PF03263.13 KIK70713.1 - 0.16 12.5 3.0 0.11 12.9 0.8 1.7 1 1 1 2 2 2 0 Cucumovirus protein 2B NinG PF05766.12 KIK70713.1 - 0.33 10.9 4.4 0.26 11.2 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein WSD PF15613.6 KIK70714.1 - 0.0066 16.9 4.1 0.032 14.7 4.1 2.2 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Peptidase_M3 PF01432.20 KIK70715.1 - 7.7e-130 434.2 0.0 9.5e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KIK70715.1 - 0.15 12.4 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Effector protein Transferase PF02458.15 KIK70716.1 - 5.7e-31 107.6 0.0 7.7e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family ABC1 PF03109.16 KIK70717.1 - 6.7e-24 84.3 0.0 1.9e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 ABC1 family ATP-synt_Z PF16594.5 KIK70717.1 - 0.064 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated APH PF01636.23 KIK70717.1 - 0.16 11.8 0.2 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_8 PF01501.20 KIK70718.1 - 3.3e-22 79.3 0.0 1.6e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 CDC73_C PF05179.14 KIK70719.1 - 2.5e-53 180.0 2.4 4.5e-53 179.1 2.4 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KIK70719.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal UBA2_C PF16195.5 KIK70719.1 - 0.092 13.4 0.2 0.52 11.0 0.1 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Fungal_trans PF04082.18 KIK70720.1 - 1.2e-07 31.1 0.1 2.1e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK70720.1 - 0.00034 20.7 5.7 0.00054 20.0 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD9 PF07147.12 KIK70721.1 - 0.01 15.1 0.8 0.014 14.7 0.4 1.3 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) Apo-CIII PF05778.12 KIK70721.1 - 0.45 10.2 6.8 0.88 9.2 0.2 3.1 2 1 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF883 PF05957.13 KIK70721.1 - 7 7.3 19.6 1.2 9.7 0.7 3.1 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Abhydrolase_3 PF07859.13 KIK70722.1 - 7.6e-10 39.0 0.0 3.1e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK70722.1 - 0.00067 18.6 0.0 0.0019 17.1 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase Aspzincin_M35 PF14521.6 KIK70723.1 - 0.03 14.9 0.6 0.41 11.2 0.1 2.6 3 0 0 3 3 3 0 Lysine-specific metallo-endopeptidase Homeobox_KN PF05920.11 KIK70726.1 - 1.9e-14 53.3 0.9 2.6e-14 52.8 0.9 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KIK70726.1 - 0.00017 21.3 0.1 0.0003 20.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KIK70727.1 - 3.5e-07 30.0 0.5 3e-06 27.0 0.0 2.6 2 1 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KIK70727.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain HTH_36 PF13730.6 KIK70727.1 - 0.015 15.2 0.1 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF600 PF04634.12 KIK70727.1 - 0.042 13.9 0.1 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF600 SKA2 PF16740.5 KIK70727.1 - 0.06 13.1 2.9 3.9 7.3 0.1 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 FRB_dom PF08771.11 KIK70727.1 - 0.28 11.6 2.5 0.85 10.1 0.0 2.5 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Pkinase PF00069.25 KIK70729.1 - 3e-63 213.7 3.3 5.1e-38 131.0 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70729.1 - 1e-37 129.9 0.0 8.1e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK70729.1 - 9.9e-05 21.8 0.0 0.00027 20.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK70729.1 - 0.036 14.0 0.2 0.036 14.0 0.2 3.0 2 2 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK70729.1 - 0.074 12.0 0.8 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Y_phosphatase3 PF13350.6 KIK70730.1 - 2.8e-54 184.5 0.0 4.3e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIK70730.1 - 8.8e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KIK70730.1 - 0.0029 17.2 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KIK70730.1 - 0.037 13.8 0.1 0.095 12.5 0.1 1.7 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.31 KIK70731.1 - 1.2e-16 60.7 25.7 1.9e-16 60.0 25.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KIK70731.1 - 3.1e-05 23.8 9.2 3.1e-05 23.8 9.2 3.2 3 1 1 4 4 4 1 Ion channel Lig_chan PF00060.26 KIK70731.1 - 0.038 13.8 2.1 0.25 11.2 1.1 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel Oxidored_FMN PF00724.20 KIK70732.1 - 2.9e-63 214.2 0.0 3.4e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fructosamin_kin PF03881.14 KIK70733.1 - 2.2e-61 207.6 0.0 2.6e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KIK70733.1 - 0.00059 19.8 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.28 KIK70734.1 - 1.6e-126 422.5 0.1 2.7e-126 421.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIK70734.1 - 5.4e-69 231.8 0.0 7.8e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KIK70734.1 - 2.9e-48 164.0 0.0 6.9e-48 162.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KIK70734.1 - 2.5e-33 114.3 0.3 6.4e-33 113.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KIK70734.1 - 8.3e-27 93.3 0.6 2.4e-26 91.8 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIK70734.1 - 1.7e-25 88.9 0.2 4.3e-25 87.7 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIK70734.1 - 1.3e-22 80.1 0.5 4.3e-22 78.4 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KIK70734.1 - 0.16 12.7 3.8 0.093 13.5 0.4 2.2 2 0 0 2 2 2 0 MRN-interacting protein Lung_7-TM_R PF06814.13 KIK70735.1 - 5.3e-65 219.6 16.6 7e-65 219.2 16.6 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4234 PF14018.6 KIK70735.1 - 0.29 11.3 5.0 0.19 11.9 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4014 PF13198.6 KIK70735.1 - 0.75 10.2 3.2 0.85 10.1 1.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) PX PF00787.24 KIK70736.1 - 5.7e-22 77.8 0.4 2.3e-21 75.9 0.4 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KIK70736.1 - 0.0001 22.0 7.0 0.0026 17.4 4.3 2.7 1 1 2 3 3 3 2 Vps5 C terminal like BAR_3 PF16746.5 KIK70736.1 - 0.015 15.0 0.6 0.07 12.8 0.1 2.1 2 0 0 2 2 2 0 BAR domain of APPL family HORMA PF02301.18 KIK70737.1 - 7e-10 38.8 0.2 1.1e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 HORMA domain 3Beta_HSD PF01073.19 KIK70739.1 - 1.4e-16 60.4 0.0 6.4e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK70739.1 - 3.3e-13 49.7 0.0 6e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK70739.1 - 8.2e-09 35.6 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK70739.1 - 1.5e-08 34.1 0.0 4.6e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIK70739.1 - 8.6e-07 28.4 0.0 0.00015 21.0 0.0 2.7 2 1 1 3 3 3 1 Male sterility protein NmrA PF05368.13 KIK70739.1 - 0.0014 18.2 0.0 0.0062 16.1 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIK70739.1 - 0.0015 18.8 0.0 0.0052 17.0 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIK70739.1 - 0.053 14.1 0.3 0.54 10.9 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PfkB PF00294.24 KIK70739.1 - 0.15 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase CLIP_SPH_mas PF18398.1 KIK70741.1 - 0.32 11.4 5.8 0.54 10.7 2.3 2.2 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade Defensin_int PF17858.1 KIK70741.1 - 1.5 8.9 7.1 6.2 6.9 1.2 2.2 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide PLDc_2 PF13091.6 KIK70742.1 - 2.9e-15 56.3 0.0 6.1e-09 35.9 0.0 2.9 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIK70742.1 - 0.00012 22.1 0.1 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KIK70742.1 - 0.00095 18.4 0.2 0.012 14.8 0.0 2.7 3 1 1 4 4 4 1 Archaeal transcriptional regulator TrmB ATG101 PF07855.12 KIK70744.1 - 6.1e-40 136.7 0.1 7e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 zf-C2H2 PF00096.26 KIK70745.1 - 9.2e-10 38.4 4.3 4.8e-06 26.7 1.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK70745.1 - 1.8e-08 34.5 3.1 0.00059 20.5 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK70745.1 - 0.00013 22.2 4.2 0.00025 21.3 0.7 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIK70745.1 - 0.001 19.3 0.6 0.002 18.4 0.5 1.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIK70745.1 - 0.0052 17.0 0.6 0.0052 17.0 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK70745.1 - 0.032 14.2 0.4 0.086 12.9 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIK70745.1 - 0.056 13.6 0.1 0.056 13.6 0.1 1.4 2 0 0 2 2 2 0 Aberrant zinc-finger zf-LYAR PF08790.11 KIK70745.1 - 0.18 11.7 1.3 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger CoA_transf_3 PF02515.17 KIK70746.1 - 0.21 10.6 1.6 0.21 10.7 0.1 1.6 2 0 0 2 2 2 0 CoA-transferase family III Myb_DNA-bind_7 PF15963.5 KIK70747.1 - 2.8e-20 72.0 0.0 6e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KIK70747.1 - 3.1e-09 36.9 0.0 5.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK70747.1 - 0.00047 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Malate_DH PF12434.8 KIK70748.1 - 0.28 11.2 4.7 0.67 10.0 4.7 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme SURF1 PF02104.15 KIK70749.1 - 5.7e-40 137.4 0.1 7.2e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.16 KIK70750.1 - 3e-72 242.9 0.0 3e-72 242.9 0.0 3.5 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KIK70750.1 - 2.1e-55 187.1 11.5 2.1e-55 187.1 11.5 6.0 6 2 1 7 7 7 2 I/LWEQ domain TcdB_N PF12918.7 KIK70750.1 - 0.001 19.3 0.1 0.0075 16.5 0.1 2.6 1 0 0 1 1 1 1 TcdB toxin N-terminal helical domain FAA_hydro_N_2 PF18288.1 KIK70750.1 - 0.024 15.0 2.8 0.15 12.5 0.8 3.4 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Ion_trans PF00520.31 KIK70752.1 - 5.6e-05 22.5 3.9 7.7e-05 22.0 3.9 1.1 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.8 KIK70753.1 - 1.8e-24 86.6 0.3 1.8e-24 86.6 0.3 4.0 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KIK70753.1 - 9e-14 51.4 12.4 9e-14 51.4 12.4 4.6 3 2 2 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ribonuclease_T2 PF00445.18 KIK70755.1 - 1e-36 126.9 0.0 1.5e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Dermcidin PF15291.6 KIK70756.1 - 0.086 13.4 0.1 0.25 11.9 0.1 1.8 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Albumin_I PF08027.11 KIK70757.1 - 0.12 12.0 0.2 0.36 10.5 0.2 1.8 1 0 0 1 1 1 0 Albumin I chain b RRM_1 PF00076.22 KIK70758.1 - 1.6e-17 63.1 0.1 9.4e-07 28.6 0.1 4.3 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK70758.1 - 0.011 15.4 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.22 KIK70759.1 - 1.9e-15 56.5 0.1 2.4e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Rep_fac_C PF08542.11 KIK70760.1 - 1.2e-25 89.7 0.0 2.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KIK70760.1 - 6.3e-13 48.8 0.1 2.9e-10 40.2 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KIK70760.1 - 2e-12 47.7 0.1 3.7e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK70760.1 - 4e-07 30.6 0.0 4.7e-05 23.8 0.0 2.6 1 1 2 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KIK70760.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK70760.1 - 2.4e-06 27.9 0.1 0.0031 17.8 0.0 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 KIK70760.1 - 1.3e-05 25.0 0.0 3.2e-05 23.7 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIK70760.1 - 3.4e-05 23.7 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KIK70760.1 - 8.5e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KIK70760.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KIK70760.1 - 0.00058 19.7 0.1 0.00094 19.0 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KIK70760.1 - 0.00064 19.2 0.0 0.0074 15.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KIK70760.1 - 0.0017 17.4 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KIK70760.1 - 0.0047 16.8 0.1 0.02 14.8 0.1 2.0 1 1 1 2 2 2 1 NTPase AAA_24 PF13479.6 KIK70760.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK70760.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK70760.1 - 0.017 15.5 0.3 0.12 12.7 0.1 2.6 2 1 0 2 2 2 0 RNA helicase AAA_assoc_2 PF16193.5 KIK70760.1 - 0.023 15.0 0.0 0.06 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain TniB PF05621.11 KIK70760.1 - 0.031 13.7 0.0 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KIK70760.1 - 0.034 14.5 0.2 0.12 12.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK70760.1 - 0.077 13.5 0.1 0.21 12.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 KIK70760.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KIK70760.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIK70760.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIK70760.1 - 0.15 11.8 0.1 0.36 10.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.25 KIK70761.1 - 1.7e-21 77.0 0.0 3e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIK70761.1 - 1.7e-08 34.7 3.1 1.7e-08 34.7 3.1 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain YPEB PF14620.6 KIK70761.1 - 0.039 13.3 0.6 0.066 12.6 0.6 1.2 1 0 0 1 1 1 0 YpeB sporulation Lzipper-MIP1 PF14389.6 KIK70761.1 - 0.047 14.0 1.7 0.11 12.8 1.7 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 KIK70761.1 - 0.27 11.8 5.3 0.56 10.7 5.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region VHS PF00790.19 KIK70762.1 - 6.8e-26 90.8 0.0 1.7e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIK70762.1 - 4.7e-07 30.0 1.4 2.4e-06 27.8 0.7 2.5 2 0 0 2 2 2 1 GAT domain DUF4404 PF14357.6 KIK70762.1 - 2.2 8.9 7.7 0.85 10.3 2.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) ALMT PF11744.8 KIK70762.1 - 5 5.8 7.7 9 5.0 7.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Utp11 PF03998.13 KIK70764.1 - 2.7e-74 250.2 24.7 3.3e-74 249.9 24.7 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KIK70764.1 - 0.071 12.4 0.4 0.13 11.6 0.4 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cauli_AT PF03233.13 KIK70764.1 - 3.9 7.4 6.4 6.5 6.7 0.1 3.0 2 1 1 3 3 3 0 Aphid transmission protein Med9 PF07544.13 KIK70764.1 - 5.4 7.2 8.1 6.8 6.9 0.7 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PI-PLC-C1 PF16670.5 KIK70765.1 - 0.00046 19.4 0.3 0.23 10.5 0.0 3.0 2 1 1 3 3 3 2 Phosphoinositide phospholipase C, Ca2+-dependent DUF512 PF04459.12 KIK70765.1 - 0.068 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) PI-PLC-X PF00388.19 KIK70765.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain HIRA_B PF09453.10 KIK70765.1 - 0.13 12.1 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 HIRA B motif IMUP PF15761.5 KIK70765.1 - 3.1 8.5 10.3 8.4 7.1 10.3 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 KIK70765.1 - 6.3 6.3 13.6 11 5.5 13.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FlgD PF03963.14 KIK70765.1 - 8.9 6.7 8.3 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region adh_short PF00106.25 KIK70766.1 - 2.5e-48 164.1 0.2 4e-48 163.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK70766.1 - 3.9e-33 115.0 0.0 5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIK70766.1 - 3.7e-07 29.9 0.0 9.5e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK70766.1 - 1.4e-06 28.4 0.1 2.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIK70766.1 - 3.5e-06 27.1 0.1 8.2e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK70766.1 - 5.1e-06 26.1 0.1 1.1e-05 25.0 0.1 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 KIK70766.1 - 0.0095 15.1 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 KIK70766.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein zf-C2H2 PF00096.26 KIK70767.1 - 5e-07 29.8 26.0 0.00053 20.3 4.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK70767.1 - 0.0024 18.2 6.4 0.0024 18.2 6.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK70767.1 - 0.033 15.0 3.9 0.033 15.0 3.9 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KIK70767.1 - 0.21 12.1 7.3 0.05 14.0 2.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zap1_zf2 PF18217.1 KIK70767.1 - 0.24 11.4 14.0 0.18 11.8 3.3 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 FOXP-CC PF16159.5 KIK70767.1 - 5 7.8 21.0 0.28 11.8 2.0 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain DUF3591 PF12157.8 KIK70768.1 - 7e-188 624.8 0.9 1.2e-187 624.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KIK70768.1 - 0.00012 21.9 2.4 0.00023 20.9 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 KIK70768.1 - 0.00045 20.3 0.1 0.001 19.2 0.1 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain BCA_ABC_TP_C PF12399.8 KIK70768.1 - 0.032 14.2 0.4 0.062 13.3 0.4 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter zf-CCHC PF00098.23 KIK70768.1 - 0.81 9.9 3.3 1.4 9.1 3.3 1.3 1 0 0 1 1 1 0 Zinc knuckle PA28_beta PF02252.18 KIK70769.1 - 6.8e-56 188.0 0.3 8.5e-56 187.7 0.3 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KIK70769.1 - 0.0022 18.0 0.1 0.0054 16.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit WD40 PF00400.32 KIK70770.1 - 1.8e-15 57.1 13.9 6.5e-05 23.6 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KIK70770.1 - 7.1e-15 55.0 0.1 9.2e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KIK70770.1 - 3.2e-05 24.1 0.5 0.17 12.2 0.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RXT2_N PF08595.11 KIK70770.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.7 3 0 0 3 3 3 0 RXT2-like, N-terminal MAPEG PF01124.18 KIK70771.1 - 3.2e-19 69.1 0.4 4e-19 68.8 0.4 1.1 1 0 0 1 1 1 1 MAPEG family Amidase PF01425.21 KIK70773.1 - 8.5e-106 354.6 0.0 1.1e-105 354.2 0.0 1.2 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 KIK70773.1 - 0.017 15.3 0.0 0.052 13.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) DnaB PF00772.21 KIK70773.1 - 0.17 12.0 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain Amidase PF01425.21 KIK70774.1 - 2.9e-101 339.7 0.0 3.6e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 KIK70774.1 - 0.0099 16.0 0.0 0.05 13.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0180) MotY_N PF18393.1 KIK70774.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 MotY N-terminal domain Ima1_N PF09779.9 KIK70775.1 - 6e-34 117.8 1.4 8.4e-34 117.3 1.4 1.2 1 0 0 1 1 1 1 Ima1 N-terminal domain Apt1 PF10351.9 KIK70776.1 - 0.00055 18.9 17.0 0.00064 18.7 17.0 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF5585 PF17823.1 KIK70776.1 - 0.028 13.4 47.8 0.046 12.7 47.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5585) SAPS PF04499.15 KIK70776.1 - 0.11 11.3 2.8 0.14 11.0 2.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SOG2 PF10428.9 KIK70776.1 - 0.24 10.6 34.4 0.36 10.0 34.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 KIK70776.1 - 0.72 8.3 25.0 1 7.9 25.0 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KIK70776.1 - 3.8 5.5 14.1 4.6 5.2 14.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.13 KIK70776.1 - 4.7 6.9 6.0 7 6.4 6.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SPX PF03105.19 KIK70776.1 - 5.8 6.7 38.3 7.8 6.3 0.0 2.0 1 1 1 2 2 2 0 SPX domain DUF4834 PF16118.5 KIK70776.1 - 8.7 7.4 0.0 8.7 7.4 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Thiolase_N PF00108.23 KIK70777.1 - 1.8e-69 234.0 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK70777.1 - 6.6e-35 119.4 0.1 1.3e-34 118.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK70777.1 - 0.00011 21.9 1.3 0.0003 20.4 0.6 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK70777.1 - 0.00048 19.9 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TatD_DNase PF01026.21 KIK70778.1 - 8.3e-44 149.9 0.0 3.1e-39 134.9 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase Glyco_transf_21 PF13506.6 KIK70779.1 - 6.3e-29 100.6 0.2 3.3e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KIK70779.1 - 2.9e-18 66.6 0.0 3.5e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK70779.1 - 2.1e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KIK70779.1 - 2.6e-06 27.5 0.2 2.6e-06 27.5 0.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Homeodomain PF00046.29 KIK70780.1 - 1.6e-08 34.2 0.9 2.4e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 Homeodomain Sec3_C PF09763.9 KIK70781.1 - 3.3e-162 541.4 0.4 4.7e-162 540.9 0.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KIK70781.1 - 1.6e-21 76.2 0.0 3.9e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KIK70781.1 - 0.0019 17.0 1.1 0.0028 16.5 0.4 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family TraB PF01963.17 KIK70781.1 - 0.29 11.0 2.8 0.31 10.9 1.1 2.0 2 0 0 2 2 2 0 TraB family GCP_N_terminal PF17681.1 KIK70781.1 - 4.1 6.9 5.2 3.8 7.1 1.9 2.3 2 1 0 2 2 2 0 Gamma tubulin complex component N-terminal TB2_DP1_HVA22 PF03134.19 KIK70782.1 - 5e-24 84.0 5.6 5e-24 84.0 5.6 1.6 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Zn_clus PF00172.18 KIK70783.1 - 2.5e-07 30.7 11.0 4.4e-07 29.9 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK70783.1 - 0.0033 16.5 0.0 0.0033 16.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain IMUP PF15761.5 KIK70783.1 - 0.2 12.3 3.7 0.87 10.3 3.7 2.0 1 0 0 1 1 1 0 Immortalisation up-regulated protein ThrE PF06738.12 KIK70784.1 - 1.6e-48 165.2 5.5 1.6e-48 165.2 5.5 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIK70784.1 - 3.6e-08 33.6 6.0 3.6e-08 33.6 6.0 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE SNF2_N PF00176.23 KIK70785.1 - 9.4e-72 241.6 0.0 2.5e-71 240.2 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK70785.1 - 5.4e-14 52.5 0.0 1.3e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KIK70785.1 - 0.0016 18.3 1.8 0.004 17.0 1.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK70785.1 - 0.002 18.0 2.0 0.002 18.0 2.0 1.7 2 0 0 2 2 2 1 zinc-RING finger domain ResIII PF04851.15 KIK70785.1 - 0.043 13.8 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KIK70785.1 - 0.77 9.7 7.6 3 7.8 7.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK70785.1 - 0.78 10.1 4.4 2.4 8.6 4.4 1.9 1 0 0 1 1 1 0 Ring finger domain CEND1 PF15677.5 KIK70785.1 - 1.3 9.5 9.6 3.3 8.3 1.3 3.1 3 0 0 3 3 3 0 Cell cycle exit and neuronal differentiation protein 1 Ribonucleas_3_3 PF14622.6 KIK70786.1 - 4.7e-07 30.0 0.0 6.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KIK70786.1 - 6.2e-06 26.8 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KIK70786.1 - 0.074 13.7 0.0 0.16 12.6 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease III domain SNF2_N PF00176.23 KIK70787.1 - 2.5e-54 184.3 0.0 3.8e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK70787.1 - 8.9e-19 67.9 0.0 2.3e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIK70787.1 - 7.2e-17 61.5 0.2 1.6e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 KIK70787.1 - 4.8e-06 26.3 7.4 0.00012 21.7 0.6 2.9 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 KIK70787.1 - 9.1e-06 25.8 0.2 2.4e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KIK70787.1 - 0.0006 19.7 0.8 0.16 11.9 0.1 3.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zinc_ribbon_5 PF13719.6 KIK70787.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain SRP54 PF00448.22 KIK70787.1 - 0.15 11.7 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PHD PF00628.29 KIK70787.1 - 0.41 10.6 9.6 0.76 9.7 0.1 3.5 4 0 0 4 4 4 0 PHD-finger C1_1 PF00130.22 KIK70787.1 - 0.68 9.9 5.7 0.46 10.4 0.1 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Esterase PF00756.20 KIK70789.1 - 7.9e-42 143.6 0.0 9.3e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KIK70789.1 - 0.0087 15.3 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIK70789.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KIK70789.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Pkinase PF00069.25 KIK70790.1 - 3e-41 141.5 0.0 4e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70790.1 - 6.2e-25 87.9 0.0 7.4e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIK70790.1 - 0.00096 19.5 0.2 0.0028 18.0 0.2 1.7 1 1 1 2 2 2 1 FHA domain MMR_HSR1 PF01926.23 KIK70791.1 - 6.8e-16 58.4 0.0 7.8e-15 55.0 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK70791.1 - 8.7e-07 29.0 0.0 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIK70791.1 - 1.1e-05 25.0 0.0 6.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KIK70791.1 - 0.00045 19.6 0.1 0.0011 18.4 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK70791.1 - 0.017 15.2 0.1 0.057 13.5 0.1 1.9 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 KIK70791.1 - 0.68 10.3 4.2 4 7.8 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain DUF4193 PF13834.6 KIK70791.1 - 3.4 8.2 8.5 4.3 7.9 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Complex1_LYR PF05347.15 KIK70792.1 - 0.0008 19.4 3.0 0.0008 19.4 3.0 2.3 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Sec8_exocyst PF04048.14 KIK70793.1 - 2.4e-32 111.8 0.1 5.2e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KIK70793.1 - 0.00012 21.5 0.4 0.00022 20.6 0.4 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF3496 PF12001.8 KIK70793.1 - 0.021 15.2 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF2451 PF10474.9 KIK70793.1 - 0.031 14.1 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) LIDHydrolase PF10230.9 KIK70794.1 - 5.6e-50 170.4 0.0 6.5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KIK70794.1 - 1.2e-08 34.6 0.0 1.4e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK70794.1 - 9.7e-08 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK70794.1 - 2.1e-06 28.5 0.1 2.6e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KIK70794.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 KIK70794.1 - 0.031 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 KIK70794.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK70795.1 - 2.2e-07 30.8 0.0 4.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KIK70795.1 - 2.6e-05 24.0 0.1 0.00019 21.2 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KIK70795.1 - 4e-05 23.6 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KIK70795.1 - 0.0017 19.0 0.1 0.0038 17.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KIK70795.1 - 0.0032 17.0 0.2 0.007 15.9 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KIK70795.1 - 0.0056 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 KIK70795.1 - 0.0058 16.0 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KIK70795.1 - 0.018 14.3 0.0 0.044 13.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIK70795.1 - 0.021 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.15 KIK70795.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase zf-C2H2_8 PF15909.5 KIK70796.1 - 0.0015 18.8 0.1 0.0017 18.6 0.1 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIK70796.1 - 0.0043 17.7 0.1 0.0087 16.7 0.0 1.5 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK70796.1 - 0.012 16.0 0.2 0.022 15.2 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK70796.1 - 0.055 14.3 0.3 0.093 13.6 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK70796.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger SF3A2 PF16835.5 KIK70797.1 - 1.1e-36 125.1 0.2 1.6e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KIK70797.1 - 1.9e-06 28.0 0.7 1.9e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KIK70797.1 - 0.0085 15.6 0.9 0.016 14.7 0.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 KIK70797.1 - 0.025 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein S1 PF00575.23 KIK70798.1 - 4.2e-60 200.0 26.3 8.2e-13 48.5 0.8 10.2 10 0 0 10 10 10 8 S1 RNA binding domain TPR_19 PF14559.6 KIK70798.1 - 8.7e-08 32.6 0.0 0.22 12.0 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK70798.1 - 3.9e-06 27.2 0.1 0.43 11.5 0.0 4.7 2 1 3 5 5 5 1 Tetratricopeptide repeat S1_2 PF13509.6 KIK70798.1 - 1e-05 25.5 2.2 21 5.2 0.0 6.1 6 0 0 6 6 6 0 S1 domain NRDE-2 PF08424.10 KIK70798.1 - 5.5e-05 22.5 7.0 0.0011 18.2 4.1 3.1 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference ANAPC3 PF12895.7 KIK70798.1 - 0.00017 21.8 0.1 0.0011 19.2 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KIK70798.1 - 0.00019 20.8 6.9 0.038 13.2 1.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK70798.1 - 0.0013 19.0 0.2 0.91 9.9 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK70798.1 - 0.0015 19.2 0.0 2.7 8.7 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat Suf PF05843.14 KIK70798.1 - 0.0019 18.3 0.2 0.0019 18.3 0.2 4.4 2 2 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_21 PF09976.9 KIK70798.1 - 0.014 15.1 0.5 0.031 14.0 0.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF1943 PF09172.11 KIK70798.1 - 0.028 13.7 0.1 0.028 13.7 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1943) Inhibitor_I69 PF13734.6 KIK70798.1 - 0.043 14.2 3.8 1 9.8 0.0 2.7 2 0 0 2 2 2 0 Spi protease inhibitor Glyco_hydro_65C PF03633.15 KIK70798.1 - 0.17 11.8 0.0 0.55 10.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain RNA_pol_Rbc25 PF08292.12 KIK70798.1 - 2.4 8.4 9.0 5.6 7.2 0.0 5.2 6 0 0 6 6 6 0 RNA polymerase III subunit Rpc25 Kelch_3 PF13415.6 KIK70799.1 - 8.5e-32 108.8 6.6 1.7e-06 28.2 0.1 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KIK70799.1 - 5.1e-29 100.0 13.4 6.1e-08 32.6 0.5 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK70799.1 - 9.9e-24 82.9 1.6 0.0014 18.6 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KIK70799.1 - 1.1e-23 82.5 0.6 2.6e-06 26.9 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KIK70799.1 - 2.4e-22 78.4 1.9 8.1e-07 29.1 0.2 6.5 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KIK70799.1 - 7.6e-14 51.0 9.4 0.015 15.3 0.2 6.5 6 1 0 6 6 6 5 Kelch motif Shugoshin_N PF07558.11 KIK70799.1 - 6 6.8 16.2 3 7.8 0.3 5.1 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Tropomyosin PF00261.20 KIK70799.1 - 6.8 6.0 104.6 0.014 14.7 17.9 5.3 2 1 3 5 5 5 0 Tropomyosin FMO-like PF00743.19 KIK70801.1 - 6.6e-11 41.3 0.1 4.5e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK70801.1 - 1.4e-07 31.6 0.0 4.3e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK70801.1 - 2.8e-06 27.2 0.9 0.035 13.7 0.3 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK70801.1 - 0.00038 19.8 0.0 0.063 12.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK70801.1 - 0.00064 19.7 0.1 0.029 14.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK70801.1 - 0.0018 17.6 0.0 0.014 14.7 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK70801.1 - 0.0019 17.4 0.1 0.64 9.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KIK70801.1 - 0.076 12.1 0.2 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Drc1-Sld2 PF11719.8 KIK70803.1 - 1.2e-07 31.7 27.6 1.1e-06 28.5 27.6 2.5 1 1 0 1 1 1 1 DNA replication and checkpoint protein PCI PF01399.27 KIK70805.1 - 1.1e-17 64.5 0.1 7.9e-17 61.7 0.0 2.5 3 1 0 3 3 3 1 PCI domain RPN5_C PF18098.1 KIK70805.1 - 7e-06 26.1 1.2 1.7e-05 24.8 1.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain YvbH_ext PF11724.8 KIK70805.1 - 0.044 14.1 0.2 15 6.0 0.0 2.9 2 1 0 2 2 2 0 YvbH-like oligomerisation region B277 PF17623.2 KIK70805.1 - 0.062 12.4 1.9 0.11 11.6 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function MRP-S25 PF13741.6 KIK70806.1 - 2e-52 178.1 2.0 8.1e-52 176.1 2.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KIK70806.1 - 0.065 13.5 1.5 0.43 10.8 1.5 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 ANAPC5 PF12862.7 KIK70807.1 - 2.2e-07 30.9 0.0 3e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 RRM_1 PF00076.22 KIK70808.1 - 2.6e-11 43.2 0.0 5.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 KIK70808.1 - 0.0036 15.7 9.0 0.0047 15.3 9.0 1.1 1 0 0 1 1 1 1 CDC45-like protein RRN3 PF05327.11 KIK70808.1 - 0.068 11.7 4.0 0.073 11.6 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-U1 PF06220.12 KIK70808.1 - 0.73 9.7 4.7 1.9 8.3 0.4 2.4 2 0 0 2 2 2 0 U1 zinc finger SNARE PF05739.19 KIK70809.1 - 1.8e-10 40.6 0.1 5.9e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KIK70809.1 - 1.2e-07 31.6 10.3 7e-06 25.8 0.4 2.4 2 1 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 KIK70809.1 - 0.00012 21.2 0.2 0.00012 21.2 0.2 2.2 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 KIK70809.1 - 0.00048 20.3 0.3 0.00048 20.3 0.3 3.1 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.16 KIK70809.1 - 0.0096 16.4 7.1 0.029 14.9 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function DUF16 Tli4_N PF18443.1 KIK70809.1 - 0.011 16.1 0.3 0.027 14.8 0.1 1.9 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain KxDL PF10241.9 KIK70809.1 - 0.64 10.3 7.6 1.7 9.0 0.6 3.5 3 2 0 3 3 3 0 Uncharacterized conserved protein CorA PF01544.18 KIK70809.1 - 1.1 8.5 4.3 2.4 7.4 1.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein BST2 PF16716.5 KIK70809.1 - 1.4 9.6 6.8 2.1 9.0 1.8 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 SlyX PF04102.12 KIK70809.1 - 2.7 8.7 9.3 1 10.0 0.3 3.4 2 1 1 3 3 3 0 SlyX UPF0242 PF06785.11 KIK70809.1 - 4.9 7.2 9.1 9.5 6.3 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NAD_Gly3P_dh_C PF07479.14 KIK70810.1 - 1.6e-48 164.6 0.2 2.5e-48 164.0 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KIK70810.1 - 3.5e-36 124.5 0.0 9.3e-36 123.2 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KIK70810.1 - 2.2e-05 24.1 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KIK70810.1 - 0.00075 20.0 0.0 0.0022 18.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrmE_N PF10396.9 KIK70810.1 - 0.0036 17.6 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 2 GTP-binding protein TrmE N-terminus NAD_binding_2 PF03446.15 KIK70810.1 - 0.035 14.3 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KIK70810.1 - 0.062 13.9 0.0 0.84 10.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIK70810.1 - 0.15 12.3 0.0 0.79 10.0 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Ank_5 PF13857.6 KIK70811.1 - 9e-09 35.4 0.0 2.6e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK70811.1 - 1.1e-08 35.5 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 KIK70811.1 - 7.1e-08 32.1 13.8 0.00019 21.2 2.9 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_4 PF13637.6 KIK70811.1 - 4.5e-07 30.3 0.0 8.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK70811.1 - 1.8e-06 28.1 0.2 2.1e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_2 PF14608.6 KIK70811.1 - 1.9e-06 28.1 17.3 3.9e-06 27.1 4.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KIK70811.1 - 1.2e-05 25.2 16.6 0.00016 21.6 2.4 2.7 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KIK70811.1 - 1.4e-05 24.9 11.7 0.007 16.2 2.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIK70811.1 - 1.8e-05 25.4 1.1 0.00055 20.6 0.1 2.9 3 0 0 3 3 3 1 Torus domain Ank_3 PF13606.6 KIK70811.1 - 9.5e-05 22.5 0.2 0.0041 17.5 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeat zf-CCCH_3 PF15663.5 KIK70811.1 - 4.4 7.6 4.5 2.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger containing family GARS_A PF01071.19 KIK70812.1 - 2.6e-73 246.0 0.1 5.8e-50 169.8 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KIK70812.1 - 1.7e-31 108.8 0.0 5.5e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KIK70812.1 - 1.8e-30 106.1 0.0 3.5e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KIK70812.1 - 1.4e-26 92.6 0.1 3.6e-26 91.3 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KIK70812.1 - 2.8e-14 53.5 1.0 7.1e-14 52.2 1.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATPgrasp_ST PF14397.6 KIK70812.1 - 0.093 12.0 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF5496 PF17600.2 KIK70812.1 - 0.2 11.7 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5496) TrbC_Ftype PF09673.10 KIK70813.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TBX PF12598.8 KIK70815.1 - 0.36 11.6 6.5 0.22 12.4 2.9 2.4 2 0 0 2 2 2 0 T-box transcription factor Gpi16 PF04113.14 KIK70817.1 - 4.7e-130 434.7 0.1 1.3e-128 429.9 0.1 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AAA PF00004.29 KIK70818.1 - 1.7e-86 287.3 0.0 1.4e-42 145.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK70818.1 - 9.2e-22 76.6 0.2 1.7e-11 43.7 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KIK70818.1 - 1.2e-13 51.1 0.0 8.3e-05 22.4 0.0 3.7 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIK70818.1 - 2.7e-13 50.4 0.0 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIK70818.1 - 2.2e-11 44.4 0.3 1.6e-05 25.3 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KIK70818.1 - 2.5e-11 43.7 0.0 2.9e-05 24.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK70818.1 - 1.9e-09 37.9 0.4 0.00044 20.5 0.0 4.6 3 2 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KIK70818.1 - 3.2e-08 33.8 0.0 0.00017 21.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIK70818.1 - 4.3e-07 29.5 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KIK70818.1 - 6.4e-07 29.3 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KIK70818.1 - 1.8e-06 28.0 0.0 0.021 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIK70818.1 - 2.1e-05 25.1 0.1 0.0084 16.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KIK70818.1 - 3.9e-05 23.6 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK70818.1 - 9.6e-05 22.7 0.0 0.056 13.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KIK70818.1 - 0.0002 20.8 0.3 0.27 10.6 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KIK70818.1 - 0.00042 19.6 0.0 0.026 13.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KIK70818.1 - 0.00043 20.6 0.0 0.066 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIK70818.1 - 0.00073 19.5 0.0 0.13 12.1 0.0 3.0 2 2 1 3 3 3 1 Rad17 P-loop domain AAA_25 PF13481.6 KIK70818.1 - 0.00081 19.0 1.6 2.1 7.9 0.0 4.1 4 1 1 5 5 5 1 AAA domain AAA_11 PF13086.6 KIK70818.1 - 0.00086 19.2 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK70818.1 - 0.00096 19.1 0.1 0.083 12.8 0.0 3.2 3 1 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.18 KIK70818.1 - 0.0012 18.7 0.0 0.18 11.6 0.0 3.0 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 KIK70818.1 - 0.0015 18.1 0.0 0.61 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 KIK70818.1 - 0.0034 17.3 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KIK70818.1 - 0.0075 16.2 1.6 6.5 6.8 0.0 3.9 4 0 0 4 4 3 0 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 KIK70818.1 - 0.011 15.4 0.0 0.67 9.6 0.0 2.9 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KIK70818.1 - 0.012 15.3 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIK70818.1 - 0.018 14.8 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KIK70818.1 - 0.018 15.0 0.0 12 5.7 0.0 3.4 3 2 2 5 5 4 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KIK70818.1 - 0.022 14.2 0.0 0.47 9.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KIK70818.1 - 0.025 15.1 0.0 0.4 11.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.9 KIK70818.1 - 0.028 13.6 0.0 0.09 11.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 KIK70818.1 - 0.041 13.1 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 KIK70818.1 - 0.043 12.9 0.0 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KIK70818.1 - 0.054 13.8 0.1 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK70818.1 - 0.074 12.8 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KIK70818.1 - 0.077 13.1 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 KIK70818.1 - 0.083 12.1 0.0 0.72 9.0 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KIK70818.1 - 0.12 12.3 0.1 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 NTPase DUF815 PF05673.13 KIK70818.1 - 0.16 11.1 0.0 3.9 6.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 KIK70818.1 - 0.2 10.5 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase Med7 PF05983.11 KIK70820.1 - 1.7e-43 148.9 1.1 3.3e-43 148.0 1.1 1.4 1 1 0 1 1 1 1 MED7 protein SNAPc_SNAP43 PF09808.9 KIK70821.1 - 8e-12 45.5 0.0 1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SKN1 PF03935.15 KIK70822.1 - 3.2e-191 636.1 1.9 3.7e-191 635.9 1.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) UQ_con PF00179.26 KIK70823.1 - 5.7e-19 68.2 0.0 1.7e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIK70823.1 - 0.0096 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain DUF4537 PF15057.6 KIK70823.1 - 0.029 14.4 0.0 0.099 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) NAT PF04768.13 KIK70824.1 - 2e-34 118.7 0.1 7.4e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Fasciclin PF02469.22 KIK70825.1 - 6e-63 210.8 0.0 4.2e-15 56.1 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 KIK70825.1 - 1e-58 195.2 3.9 1e-19 70.3 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein YGGT PF02325.17 KIK70825.1 - 0.065 13.7 0.2 0.82 10.1 0.1 2.4 2 0 0 2 2 2 0 YGGT family TT_ORF1 PF02956.14 KIK70825.1 - 0.19 10.4 0.1 0.3 9.7 0.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 Rav1p_C PF12234.8 KIK70826.1 - 4.1e-206 686.2 0.0 5.6e-206 685.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal zf-CCHC PF00098.23 KIK70827.1 - 5.3e-11 42.1 22.4 0.00027 20.9 1.8 4.3 4 0 0 4 4 4 4 Zinc knuckle PHD_4 PF16866.5 KIK70827.1 - 8.7e-05 22.5 5.0 0.019 15.1 0.5 2.3 2 0 0 2 2 2 2 PHD-finger zf-CCHC_2 PF13696.6 KIK70827.1 - 0.00039 20.2 3.8 0.0057 16.4 0.4 4.4 4 1 1 5 5 5 2 Zinc knuckle zf-CCHC_4 PF14392.6 KIK70827.1 - 0.0016 18.1 21.0 1 9.1 0.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-RING_9 PF13901.6 KIK70827.1 - 0.032 14.2 8.9 0.24 11.3 1.5 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FAD_binding_4 PF01565.23 KIK70828.1 - 1.7e-21 76.4 2.7 2.7e-21 75.8 2.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK70828.1 - 8.7e-06 25.7 0.6 1.9e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 Berberine and berberine like CbiJ PF02571.14 KIK70828.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK WW PF00397.26 KIK70829.1 - 5.3e-07 29.6 5.6 1e-06 28.7 5.6 1.5 1 0 0 1 1 1 1 WW domain Zn_clus PF00172.18 KIK70832.1 - 0.00011 22.2 7.7 0.00019 21.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCCL PF03815.19 KIK70833.1 - 6.8e-13 48.5 0.0 1.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.14 KIK70837.1 - 5.8e-20 72.2 0.2 1.1e-17 64.8 0.0 2.9 1 1 1 2 2 2 1 Putative adipose-regulatory protein (Seipin) Ice_nucleation PF00818.17 KIK70837.1 - 7.2 6.9 5.8 5.4 7.3 3.1 2.2 2 0 0 2 2 2 0 Ice nucleation protein repeat Ank_2 PF12796.7 KIK70838.1 - 1.8e-18 66.9 1.2 3.8e-13 49.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK70838.1 - 8.7e-16 58.1 0.1 9.9e-13 48.3 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DnaJ PF00226.31 KIK70838.1 - 3.1e-12 46.4 0.1 9.5e-12 44.9 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Ank_3 PF13606.6 KIK70838.1 - 2e-11 43.1 0.0 0.01 16.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KIK70838.1 - 1.9e-08 34.4 0.1 0.012 16.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK70838.1 - 6.7e-05 23.1 0.0 0.57 10.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Rap1_C PF11626.8 KIK70838.1 - 0.0018 18.3 0.2 0.0049 16.9 0.2 1.9 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short_C2 PF13561.6 KIK70840.1 - 1.8e-43 148.8 0.0 2.4e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70840.1 - 1e-41 142.5 0.0 1.5e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70840.1 - 5.4e-09 36.2 0.0 8.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK70840.1 - 0.0047 16.4 0.0 0.0097 15.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SH3BGR PF04908.15 KIK70841.1 - 8.5e-12 45.1 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KIK70841.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin LMWPc PF01451.21 KIK70842.1 - 2e-38 132.0 0.0 2.3e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Aldedh PF00171.22 KIK70843.1 - 5.9e-130 433.9 0.1 6.7e-130 433.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK70843.1 - 0.0037 16.4 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) T6SS_VasJ PF16989.5 KIK70843.1 - 0.025 14.0 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ DNApol3-delta_C PF09115.10 KIK70844.1 - 0.26 11.8 1.8 13 6.3 0.8 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal GDI PF00996.18 KIK70845.1 - 7.2e-220 729.9 0.1 8.3e-220 729.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KIK70845.1 - 0.012 15.8 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TRAPPC-Trs85 PF12739.7 KIK70846.1 - 3.5e-35 121.8 0.0 4.4e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KIK70846.1 - 0.00098 16.6 0.0 0.0017 15.8 0.0 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mpv17_PMP22 PF04117.12 KIK70847.1 - 2.6e-13 50.0 1.5 1.4e-12 47.7 2.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Mito_carr PF00153.27 KIK70848.1 - 9.7e-29 99.1 8.9 2.9e-14 52.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATG16 PF08614.11 KIK70849.1 - 5.7e-05 23.4 12.5 5.7e-05 23.4 12.5 8.8 1 1 6 7 7 7 3 Autophagy protein 16 (ATG16) Tektin PF03148.14 KIK70849.1 - 0.00051 18.9 12.9 0.00051 18.9 12.9 8.2 3 2 5 9 9 9 2 Tektin family Filament PF00038.21 KIK70849.1 - 0.00093 18.9 114.5 0.0026 17.4 45.3 5.3 1 1 4 5 5 5 4 Intermediate filament protein TMF_TATA_bd PF12325.8 KIK70849.1 - 0.0013 18.9 10.7 0.0013 18.9 10.7 10.5 1 1 10 11 11 11 4 TATA element modulatory factor 1 TATA binding DUF2968 PF11180.8 KIK70849.1 - 0.0024 17.5 8.0 0.0024 17.5 8.0 8.6 1 1 7 8 8 8 1 Protein of unknown function (DUF2968) Fez1 PF06818.15 KIK70849.1 - 0.0038 17.7 120.6 0.027 14.9 11.1 6.9 1 1 5 7 7 7 3 Fez1 BST2 PF16716.5 KIK70849.1 - 0.023 15.3 2.9 0.023 15.3 2.9 10.4 4 3 5 10 10 10 0 Bone marrow stromal antigen 2 Shugoshin_N PF07558.11 KIK70849.1 - 1.1 9.1 13.6 2 8.4 0.1 5.1 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Img2 PF05046.14 KIK70849.1 - 2.3 8.5 5.4 55 4.2 3.1 4.0 3 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) His_Phos_1 PF00300.22 KIK70850.1 - 2.2e-38 131.9 0.1 2.7e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pep3_Vps18 PF05131.14 KIK70851.1 - 2.8e-50 170.0 0.0 8.1e-50 168.5 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KIK70851.1 - 3.5e-09 36.7 7.0 0.00072 19.4 0.4 3.4 2 2 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KIK70851.1 - 4.8e-05 23.8 0.1 0.0002 21.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KIK70851.1 - 0.0012 18.8 1.6 0.0012 18.8 1.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK70851.1 - 0.0037 17.1 1.7 0.0037 17.1 1.7 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK70851.1 - 0.0069 16.7 4.6 0.0071 16.7 1.4 2.5 2 0 0 2 2 2 1 Ring finger domain Zn_ribbon_17 PF17120.5 KIK70851.1 - 0.13 11.9 1.2 0.43 10.2 1.2 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KIK70851.1 - 0.17 12.0 5.5 0.053 13.6 1.8 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 KIK70851.1 - 0.18 11.6 9.0 0.059 13.1 4.6 2.4 2 0 0 2 2 2 0 RING-like zinc finger Zf_RING PF16744.5 KIK70851.1 - 0.19 11.9 0.1 0.51 10.5 0.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 KIK70851.1 - 3.1 7.8 6.8 0.31 11.0 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cgr1 PF03879.14 KIK70852.1 - 9.4e-17 61.4 2.6 1e-16 61.2 2.6 1.0 1 0 0 1 1 1 1 Cgr1 family SGS PF05002.15 KIK70852.1 - 0.014 15.5 0.7 0.014 15.5 0.7 1.8 2 0 0 2 2 2 0 SGS domain MBDa PF16564.5 KIK70852.1 - 0.064 13.4 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD TPR_MLP1_2 PF07926.12 KIK70853.1 - 0.18 11.8 1.6 0.33 11.0 1.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Sec39 PF08314.11 KIK70854.1 - 8.1e-99 332.1 0.8 1.2e-98 331.6 0.8 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 CN_hydrolase PF00795.22 KIK70855.1 - 3e-41 141.5 0.0 3.7e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase UPF0113_N PF17833.1 KIK70856.1 - 2.2e-29 101.8 0.1 3.4e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KIK70856.1 - 2.1e-27 95.2 0.0 1.1e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 UPF0113 PUA domain HpuA PF16960.5 KIK70856.1 - 0.012 14.8 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter DUF1825 PF08855.10 KIK70856.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) NRDE-2 PF08424.10 KIK70857.1 - 6.4e-66 222.7 1.4 6.4e-66 222.7 1.4 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KIK70857.1 - 0.0081 16.9 18.8 4.6 8.3 0.2 6.7 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK70857.1 - 0.69 10.2 3.3 5.6 7.3 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat UreD PF01774.17 KIK70859.1 - 4.2e-65 219.6 0.0 5e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Peptidase_M41 PF01434.18 KIK70860.1 - 3.2e-61 206.5 0.0 4.7e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIK70860.1 - 8.1e-42 142.8 0.0 1.7e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK70860.1 - 4.8e-15 55.1 0.1 1.3e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KIK70860.1 - 9.9e-12 45.2 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 KIK70860.1 - 0.0015 18.9 1.4 0.11 12.8 0.1 3.3 3 1 0 4 4 4 1 AAA ATPase domain TIP49 PF06068.13 KIK70860.1 - 0.0021 17.3 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KIK70860.1 - 0.035 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK70860.1 - 0.036 14.4 0.2 1.6 9.0 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK70860.1 - 0.055 13.5 0.0 0.22 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK70860.1 - 0.075 13.1 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KIK70860.1 - 0.099 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIK70860.1 - 0.2 11.0 0.1 0.51 9.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Tim17 PF02466.19 KIK70861.1 - 0.00089 19.6 1.4 1.1 9.6 0.1 3.4 4 0 0 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 KIK70861.1 - 0.024 15.2 0.2 9.8 6.8 0.1 2.4 1 1 1 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 Hydrolase_4 PF12146.8 KIK70862.1 - 6e-16 58.4 0.0 9.6e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK70862.1 - 6.1e-16 58.8 0.2 2.4e-14 53.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK70862.1 - 8.7e-16 59.2 0.0 1.9e-15 58.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KIK70862.1 - 6.4e-06 26.0 0.1 0.045 13.5 0.2 2.8 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KIK70862.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 KIK70862.1 - 0.00072 19.2 0.1 0.055 13.0 0.3 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIK70862.1 - 0.0034 16.9 0.1 0.29 10.6 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KIK70862.1 - 0.0084 16.0 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 KIK70862.1 - 0.011 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.16 KIK70862.1 - 0.076 12.8 0.0 0.46 10.3 0.0 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 KIK70862.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 KIK70862.1 - 0.19 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ANAPC4_WD40 PF12894.7 KIK70863.1 - 6.4e-11 42.4 0.0 0.0014 18.9 0.0 5.0 5 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK70863.1 - 3.6e-07 30.8 3.5 0.041 14.8 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 KIK70863.1 - 2.3e-05 24.4 0.0 1.7 8.5 0.0 4.5 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK70863.1 - 0.23 11.5 1.7 44 4.2 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ribosomal_S17 PF00366.20 KIK70864.1 - 5.9e-20 71.1 0.9 7.7e-20 70.8 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Prefoldin_2 PF01920.20 KIK70865.1 - 1.3e-23 83.0 10.5 1.5e-23 82.8 10.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.6 KIK70865.1 - 0.01 15.6 6.2 0.02 14.6 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) FPP PF05911.11 KIK70865.1 - 0.02 13.1 9.4 0.024 12.9 9.4 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 KIK70865.1 - 0.026 15.0 11.6 0.041 14.3 2.8 2.1 1 1 0 2 2 2 0 Fez1 Tropomyosin_1 PF12718.7 KIK70865.1 - 0.026 14.7 10.4 0.56 10.3 1.8 2.2 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 KIK70865.1 - 0.039 12.8 14.7 0.22 10.4 14.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein End3 PF12761.7 KIK70865.1 - 0.041 14.0 6.9 0.054 13.7 6.9 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6_N PF17675.1 KIK70865.1 - 0.051 14.1 11.5 0.041 14.4 2.2 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Rx_N PF18052.1 KIK70865.1 - 0.06 13.6 5.0 0.18 12.1 0.3 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DUF4139 PF13598.6 KIK70865.1 - 0.065 12.9 2.0 0.081 12.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) NPV_P10 PF05531.12 KIK70865.1 - 0.069 13.6 7.2 0.64 10.5 1.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 KIK70865.1 - 0.098 13.0 7.7 4.1 7.8 1.8 3.1 1 1 2 3 3 3 0 Tup N-terminal YojJ PF10372.9 KIK70865.1 - 0.2 11.8 4.9 0.59 10.3 1.1 2.6 2 2 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FliD_C PF07195.12 KIK70865.1 - 0.26 10.7 7.7 0.28 10.6 6.3 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus MtrG PF04210.13 KIK70865.1 - 0.27 11.1 4.2 0.5 10.2 0.8 2.7 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G MCU PF04678.13 KIK70865.1 - 0.39 10.8 2.6 0.72 9.9 2.6 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter GAS PF13851.6 KIK70865.1 - 0.41 10.0 13.0 0.27 10.6 3.7 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KIK70865.1 - 0.5 10.4 11.6 0.56 10.2 3.7 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 KIK70865.1 - 0.63 10.4 10.3 0.49 10.7 4.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) COG5 PF10392.9 KIK70865.1 - 0.72 10.0 6.0 6.4 7.0 0.4 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 HIP1_clath_bdg PF16515.5 KIK70865.1 - 0.84 10.3 10.9 3.9 8.1 2.2 2.2 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KIK70865.1 - 0.93 9.5 8.0 7.5 6.6 2.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KIK70865.1 - 1.2 9.9 8.1 0.75 10.5 1.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KIK70865.1 - 1.2 9.4 11.8 7.6 6.9 2.7 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain DMPK_coil PF08826.10 KIK70865.1 - 2.2 8.5 13.4 0.33 11.1 2.4 2.6 2 1 0 2 2 2 0 DMPK coiled coil domain like YgaB PF14182.6 KIK70865.1 - 3 8.3 10.6 1.4 9.4 2.8 2.8 1 1 1 2 2 2 0 YgaB-like protein XhlA PF10779.9 KIK70865.1 - 3.1 8.1 8.5 0.4 10.9 3.0 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 KIK70865.1 - 3.2 8.0 10.2 1.1 9.5 2.6 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 KIK70865.1 - 3.9 7.4 11.1 61 3.5 11.1 2.3 1 1 0 1 1 1 0 Prefoldin subunit COG2 PF06148.11 KIK70865.1 - 3.9 7.6 8.5 11 6.1 1.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KIK70865.1 - 4.4 7.8 8.1 9 6.8 3.4 2.6 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KIK70865.1 - 4.5 7.4 10.8 26 5.0 10.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KIK70865.1 - 4.8 7.0 11.1 3.2 7.5 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) LMBR1 PF04791.16 KIK70865.1 - 5 5.9 7.7 6.5 5.5 0.7 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF4404 PF14357.6 KIK70865.1 - 5.4 7.7 10.7 4.1 8.1 0.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 KIK70865.1 - 6.1 6.0 9.5 6.3 5.9 1.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein G_glu_transpept PF01019.21 KIK70866.1 - 2.7e-146 488.3 0.0 3.1e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PP2C PF00481.21 KIK70867.1 - 1.4e-35 123.2 0.0 4.6e-34 118.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Phytochelatin PF05023.14 KIK70867.1 - 0.015 14.5 0.1 0.034 13.4 0.1 1.5 2 0 0 2 2 2 0 Phytochelatin synthase Git3 PF11710.8 KIK70868.1 - 0.00019 21.3 10.9 0.00092 19.0 10.9 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Snf7 PF03357.21 KIK70869.1 - 1.5e-36 125.6 9.6 1.8e-36 125.4 9.6 1.0 1 0 0 1 1 1 1 Snf7 Peptidase_M3_N PF08439.10 KIK70869.1 - 0.47 10.8 7.0 0.66 10.3 0.9 2.5 2 0 0 2 2 2 0 Oligopeptidase F Mod_r PF07200.13 KIK70869.1 - 1.9 8.6 15.5 2.9 8.0 2.8 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Pro_isomerase PF00160.21 KIK70870.1 - 1.7e-43 148.7 0.0 2.4e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 KIK70870.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KIK70870.1 - 0.093 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 U-box domain DUF730 PF05325.11 KIK70870.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) PPR_2 PF13041.6 KIK70871.1 - 3.7e-45 151.9 0.2 1.2e-08 35.0 0.0 9.1 5 3 4 9 9 9 9 PPR repeat family PPR_3 PF13812.6 KIK70871.1 - 3.3e-32 110.4 0.2 1.1e-07 31.9 0.0 6.1 4 2 4 8 8 8 6 Pentatricopeptide repeat domain PPR PF01535.20 KIK70871.1 - 2.2e-19 68.3 5.3 6e-05 23.0 0.0 10.1 13 0 0 13 13 13 3 PPR repeat PPR_1 PF12854.7 KIK70871.1 - 5.7e-19 67.5 0.1 0.12 12.1 0.0 9.0 9 0 0 9 9 9 6 PPR repeat PPR_long PF17177.4 KIK70871.1 - 7.1e-11 41.9 0.0 1.4e-07 31.1 0.1 2.8 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP MNE1 PF13762.6 KIK70871.1 - 0.022 14.7 1.2 0.16 12.0 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component RPM2 PF08579.11 KIK70871.1 - 0.14 12.6 0.0 99 3.4 0.0 3.9 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Lem_TRP PF08262.11 KIK70871.1 - 0.18 11.8 0.8 0.51 10.4 0.8 1.8 1 0 0 1 1 1 0 Leucophaea maderae tachykinin-related peptide TPR_12 PF13424.6 KIK70872.1 - 0.048 14.0 0.3 0.055 13.8 0.3 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KIK70873.1 - 1.3e-104 350.6 13.3 1.5e-104 350.4 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK70873.1 - 6.8e-30 104.2 36.4 1.5e-25 89.9 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.12 KIK70873.1 - 0.094 12.8 3.4 0.074 13.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) UNC-93 PF05978.16 KIK70873.1 - 0.096 12.4 5.4 4.2 7.1 0.9 2.4 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DEAD PF00270.29 KIK70874.1 - 7.8e-16 58.3 0.0 3.8e-15 56.1 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK70874.1 - 5.5e-06 26.7 0.0 2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain E1-E2_ATPase PF00122.20 KIK70875.1 - 0.0012 18.4 0.7 0.0015 18.1 0.7 1.1 1 0 0 1 1 1 1 E1-E2 ATPase DUF4203 PF13886.6 KIK70875.1 - 0.018 14.7 0.0 0.018 14.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) DUF3446 PF11928.8 KIK70875.1 - 5.4 7.4 38.8 11 6.4 13.4 2.3 1 1 1 2 2 2 0 Early growth response N-terminal domain Drc1-Sld2 PF11719.8 KIK70875.1 - 7.7 5.9 9.3 9.2 5.7 9.3 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4203 PF13886.6 KIK70876.1 - 2.3e-43 148.2 25.3 3.1e-43 147.8 25.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Endostatin PF06482.11 KIK70876.1 - 0.31 10.5 3.6 0.54 9.7 3.6 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4407 PF14362.6 KIK70876.1 - 1.3 8.3 9.5 4.2 6.6 9.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LAG1-DNAbind PF09271.11 KIK70877.1 - 1.1e-27 97.5 0.1 1.5e-16 61.4 0.1 2.3 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 KIK70877.1 - 1.9e-22 80.1 0.0 4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.21 KIK70878.1 - 7.5e-165 547.9 1.0 9.4e-165 547.6 1.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KIK70878.1 - 1.9e-37 128.0 0.0 4.7e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KIK70878.1 - 3.1e-05 23.2 0.6 7.9e-05 21.9 0.6 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KIK70878.1 - 0.0028 16.7 0.1 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Ribul_P_3_epim PF00834.19 KIK70879.1 - 7.3e-56 188.7 0.0 8.9e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 KIK70879.1 - 0.085 13.1 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 Predicted Peptidoglycan domain DRMBL PF07522.14 KIK70880.1 - 0.043 14.0 0.6 0.056 13.6 0.6 1.3 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase COX6A PF02046.15 KIK70881.1 - 4.7e-31 107.6 0.1 5.6e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa 2-Hacid_dh_C PF02826.19 KIK70882.1 - 2e-56 190.1 0.0 3.7e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RPN2_C PF18004.1 KIK70882.1 - 6.9e-44 149.6 2.7 3.2e-43 147.4 1.8 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KIK70882.1 - 5e-31 105.6 30.8 6.4e-09 35.8 0.0 10.2 11 0 0 11 11 11 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIK70882.1 - 6.8e-18 64.8 0.6 3e-14 53.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats 2-Hacid_dh PF00389.30 KIK70882.1 - 3.9e-10 39.5 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK70882.1 - 2.4e-06 27.8 0.2 4.5e-05 23.7 0.0 2.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HEAT PF02985.22 KIK70882.1 - 9.6e-05 22.3 0.2 8.5 6.9 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KIK70882.1 - 0.0013 19.1 0.7 1.2 9.7 0.0 4.3 3 1 1 4 4 4 2 HEAT-like repeat Arm PF00514.23 KIK70883.1 - 3.9e-93 303.0 13.9 4.8e-13 48.7 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KIK70883.1 - 1.4e-23 83.1 1.4 3e-23 82.1 1.4 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KIK70883.1 - 2.4e-23 82.2 3.3 7.3e-09 35.9 0.1 5.9 3 1 3 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 KIK70883.1 - 6.8e-21 73.6 0.3 1.4e-20 72.6 0.3 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KIK70883.1 - 6.2e-17 61.8 1.7 3.6e-05 24.1 0.0 6.0 2 1 4 7 7 7 6 HEAT repeats HEAT PF02985.22 KIK70883.1 - 2.6e-15 55.2 0.3 0.00094 19.2 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 KIK70883.1 - 7.7e-06 25.5 0.1 0.2 11.1 0.0 4.1 2 1 1 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KIK70883.1 - 8.9e-06 24.5 0.0 0.0011 17.7 0.0 2.7 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 KIK70883.1 - 1.3e-05 25.3 2.6 0.03 14.6 0.1 4.3 3 2 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KIK70883.1 - 0.00018 21.6 0.3 0.66 10.1 0.0 4.0 3 3 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 KIK70883.1 - 0.00023 21.5 1.1 0.69 10.8 0.1 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KIK70883.1 - 0.0053 16.2 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Mo25-like NopRA1 PF16201.5 KIK70883.1 - 0.027 14.1 0.1 24 4.4 0.1 4.2 2 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 V-ATPase_H_N PF03224.14 KIK70883.1 - 0.042 13.1 0.0 3.1 7.0 0.0 3.0 1 1 0 2 2 2 0 V-ATPase subunit H DUF3552 PF12072.8 KIK70883.1 - 2.2 7.6 7.3 3.7 6.9 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) LSM PF01423.22 KIK70884.1 - 3.3e-21 74.8 0.1 3.7e-21 74.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK70884.1 - 0.022 14.9 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S16 PF00886.19 KIK70885.1 - 4.1e-20 71.6 0.0 6.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.19 KIK70886.1 - 2.2e-17 63.1 0.0 3.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 KIK70886.1 - 6.3e-16 58.2 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK70886.1 - 2.9e-14 53.2 0.4 5.2e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK70886.1 - 3.8e-12 46.1 1.6 4.4e-08 33.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KIK70886.1 - 4.2e-12 46.5 0.1 7.2e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIK70886.1 - 1.9e-08 33.9 0.3 3e-07 30.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat VWA_3_C PF18571.1 KIK70886.1 - 0.15 11.9 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain CoA_binding PF02629.19 KIK70887.1 - 5.6e-30 103.9 0.2 5.6e-30 103.9 0.2 1.9 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 KIK70887.1 - 5.5e-17 62.0 0.1 1e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KIK70887.1 - 1.3e-10 41.2 0.1 4.1e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIK70887.1 - 1.6e-05 25.4 0.4 7.7e-05 23.2 0.0 2.2 3 1 1 4 4 4 1 CoA binding domain GFO_IDH_MocA PF01408.22 KIK70887.1 - 0.01 16.6 0.0 0.032 15.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KIK70887.1 - 0.055 13.6 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Toprim_Crpt PF13342.6 KIK70887.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Xpo1 PF08389.12 KIK70888.1 - 3.2e-20 72.7 0.2 6e-18 65.3 0.0 3.9 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KIK70888.1 - 1.2e-06 28.3 0.0 2e-05 24.4 0.0 3.0 3 1 1 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 KIK70888.1 - 0.14 12.5 0.1 12 6.5 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Importin_rep PF18773.1 KIK70888.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat Septin PF00735.18 KIK70889.1 - 2.4e-121 404.3 0.2 2.4e-121 404.3 0.2 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIK70889.1 - 1.1e-07 31.9 1.0 3e-07 30.5 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK70889.1 - 3.2e-05 23.5 5.5 0.0066 16.0 0.0 3.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK70889.1 - 0.00031 20.7 10.6 0.00031 20.7 0.6 3.3 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KIK70889.1 - 0.0013 19.0 0.1 0.0077 16.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 KIK70889.1 - 0.0019 17.6 0.5 0.0069 15.7 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KIK70889.1 - 0.0069 16.5 4.6 1 9.4 0.1 3.4 2 1 0 3 3 3 2 Dynamin family Ras PF00071.22 KIK70889.1 - 0.0082 15.8 0.4 0.042 13.5 0.0 2.4 3 1 1 4 4 4 1 Ras family AAA_29 PF13555.6 KIK70889.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK70889.1 - 0.012 16.1 10.2 12 6.4 10.2 3.1 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 KIK70889.1 - 0.015 15.5 0.0 0.051 13.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK70889.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Strep_SA_rep PF06696.11 KIK70889.1 - 2.7 8.1 12.5 0.23 11.5 3.7 2.5 1 1 1 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 KIK70889.1 - 3.6 7.3 9.4 2.3 7.9 0.1 3.5 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KIK70889.1 - 7 6.1 8.9 2 7.9 6.1 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit CN_hydrolase PF00795.22 KIK70890.1 - 3.3e-56 190.5 0.0 3.8e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CxC7 PF18866.1 KIK70890.1 - 0.13 12.4 0.6 8.9 6.5 0.0 2.9 3 0 0 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases MRP-S28 PF10213.9 KIK70891.1 - 5.1e-29 101.3 0.0 7.4e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.13 KIK70892.1 - 2.3e-54 183.5 0.0 2.6e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 KIK70892.1 - 0.28 11.1 4.4 0.4 10.6 0.1 2.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Pkinase PF00069.25 KIK70895.1 - 3.8e-64 216.6 0.0 5.2e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70895.1 - 1.2e-41 142.7 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK70895.1 - 4.4e-07 29.5 0.0 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIK70895.1 - 0.022 13.5 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ras_bdg_2 PF14847.6 KIK70895.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Kdo PF06293.14 KIK70895.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLTH PF10607.9 KIK70896.1 - 2.8e-33 114.9 0.4 3.5e-33 114.6 0.4 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIK70896.1 - 1.7e-06 27.7 0.3 4.3e-06 26.5 0.3 1.7 1 0 0 1 1 1 1 LisH Spo0M PF07070.11 KIK70896.1 - 0.068 12.7 0.2 0.098 12.2 0.2 1.2 1 0 0 1 1 1 0 SpoOM protein Rrp15p PF07890.12 KIK70897.1 - 4.3e-28 98.3 1.5 4.3e-28 98.3 1.5 2.0 1 1 1 2 2 2 1 Rrp15p SIR4_SID PF16991.5 KIK70897.1 - 0.18 11.8 6.7 0.11 12.5 3.6 2.0 2 0 0 2 2 2 0 Sir4 SID domain DIL PF01843.19 KIK70898.1 - 2.3e-28 98.5 0.4 9.3e-28 96.6 0.1 2.0 2 0 0 2 2 2 1 DIL domain Ank_4 PF13637.6 KIK70898.1 - 5.7e-08 33.2 0.1 9.8e-06 26.0 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK70898.1 - 2.7e-06 27.9 0.0 1.3e-05 25.7 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK70898.1 - 4.1e-05 23.8 1.9 0.046 14.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK70898.1 - 0.00013 22.1 0.2 0.017 15.6 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KIK70898.1 - 0.00024 21.3 0.0 0.0018 18.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Cas1_AcylT PF07779.12 KIK70899.1 - 1.8e-140 469.0 18.1 2.4e-140 468.6 18.1 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KIK70899.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF2871 PF11070.8 KIK70899.1 - 0.018 15.3 1.3 0.077 13.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Cut8 PF08559.10 KIK70900.1 - 3.8e-18 66.0 0.0 7.4e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein RNase_T PF00929.24 KIK70902.1 - 2.7e-07 31.3 0.0 3.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF3025 PF11227.8 KIK70902.1 - 0.037 13.8 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Mito_carr PF00153.27 KIK70903.1 - 1.9e-47 159.2 0.3 5.6e-18 64.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINGv PF12906.7 KIK70904.1 - 1.3e-12 47.6 5.4 2.2e-12 46.9 5.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIK70904.1 - 0.0038 17.5 4.2 0.0067 16.7 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.29 KIK70904.1 - 0.35 10.8 3.8 0.6 10.1 3.8 1.4 1 0 0 1 1 1 0 PHD-finger Nucleoporin_N PF08801.11 KIK70905.1 - 5.6e-66 223.1 1.1 1.5e-65 221.7 1.1 1.6 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KIK70905.1 - 2.6e-36 125.6 0.0 1.5e-35 123.0 0.0 2.1 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Ribonuclease_3 PF00636.26 KIK70906.1 - 1.3e-08 35.4 0.0 3.1e-05 24.5 0.0 2.5 1 1 1 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK70906.1 - 6.6e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Pkinase PF00069.25 KIK70907.1 - 2.3e-66 223.9 0.0 2.6e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70907.1 - 1.5e-42 145.7 0.0 1.9e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK70907.1 - 2.9e-09 36.7 0.0 1.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIK70907.1 - 0.0012 17.7 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK70907.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK70907.1 - 0.026 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK70907.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KIK70907.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NAD_binding_6 PF08030.12 KIK70908.1 - 7.2e-24 84.7 0.0 1.7e-23 83.5 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK70908.1 - 1.1e-21 77.0 0.0 2.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIK70908.1 - 5.9e-18 65.2 12.2 1.1e-17 64.4 12.2 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KIK70908.1 - 0.0047 17.5 0.0 0.043 14.5 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 KIK70908.1 - 0.039 14.0 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform FAD_binding_6 PF00970.24 KIK70908.1 - 0.058 13.7 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HORMA PF02301.18 KIK70909.1 - 1.1e-17 64.4 0.1 2.3e-17 63.3 0.1 1.5 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KIK70909.1 - 0.0001 22.3 0.2 0.00059 19.9 0.2 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 WD40 PF00400.32 KIK70910.1 - 5.4e-41 137.8 13.3 8e-08 32.8 0.4 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KIK70910.1 - 1.3e-29 103.1 0.0 4.1e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KIK70910.1 - 8.6e-10 38.8 0.0 0.002 18.4 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KIK70910.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 KIK70910.1 - 0.0023 16.7 0.5 4.4 5.8 0.0 3.6 4 0 0 4 4 4 1 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK70910.1 - 0.0046 16.9 0.0 1.3 8.8 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 KIK70910.1 - 0.085 11.5 0.0 0.26 9.8 0.0 1.7 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin tRNA_U5-meth_tr PF05958.11 KIK70911.1 - 0.057 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FXR_C1 PF16096.5 KIK70911.1 - 0.77 10.0 4.4 1.6 9.0 4.4 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF2189 PF09955.9 KIK70912.1 - 0.051 13.8 0.8 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) EphA2_TM PF14575.6 KIK70912.1 - 0.053 14.4 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK70912.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless UL45 PF05473.12 KIK70912.1 - 0.35 10.5 1.3 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Meth_synt_2 PF01717.18 KIK70913.1 - 2e-20 73.3 0.0 1.1e-17 64.3 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIK70913.1 - 6.4e-06 25.9 0.0 0.038 13.5 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain CAT PF00302.18 KIK70913.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase Ribosomal_L13e PF01294.18 KIK70914.1 - 1.6e-73 246.4 3.0 2.8e-73 245.6 3.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13e Pal1 PF08316.11 KIK70915.1 - 5.6e-18 66.0 1.0 1.5e-17 64.6 1.0 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein His_biosynth PF00977.21 KIK70916.1 - 6.6e-44 150.1 0.1 5.2e-43 147.1 0.1 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KIK70916.1 - 3.6e-18 66.0 0.0 6.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KIK70916.1 - 5.5e-08 32.9 0.0 6.7e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIK70916.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KIK70916.1 - 0.014 15.2 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 0 Peptidase C26 Peptidase_S51 PF03575.17 KIK70916.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 2-Hacid_dh_C PF02826.19 KIK70917.1 - 2e-50 170.7 0.0 4.1e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK70917.1 - 1.2e-32 112.4 0.0 1.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK70917.1 - 0.038 14.2 0.1 0.098 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KIK70917.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F-box-like PF12937.7 KIK70918.1 - 1e-08 34.9 3.6 1e-08 34.9 3.6 2.2 2 1 0 2 2 2 1 F-box-like Ribosomal_L4 PF00573.22 KIK70919.1 - 4.2e-58 196.2 0.0 4.9e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 KIK70920.1 - 1e-32 113.2 0.7 1.2e-32 113.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 KIK70921.1 - 4e-20 72.0 0.0 4.5e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK70921.1 - 3.5e-06 27.3 0.1 9.5e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Tim17 PF02466.19 KIK70922.1 - 1e-07 32.3 11.8 7e-07 29.6 7.8 2.3 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 KIK70923.1 - 1.8e-05 25.4 1.9 0.012 16.4 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat adh_short_C2 PF13561.6 KIK70924.1 - 2.1e-59 200.9 0.0 2.5e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK70924.1 - 1.1e-45 155.5 0.0 1.4e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK70924.1 - 5.3e-14 52.5 0.0 7.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Sybindin PF04099.12 KIK70924.1 - 0.054 13.4 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family Cupin_2 PF07883.11 KIK70925.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KIK70925.1 - 0.0048 16.6 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Auxin_BP PF02041.16 KIK70925.1 - 0.031 14.0 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Pex16 PF08610.10 KIK70926.1 - 1.7e-107 359.3 0.9 2e-107 359.1 0.9 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) HMMR_N PF15905.5 KIK70927.1 - 0.00058 19.4 4.4 0.00093 18.8 4.4 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal HGD-D PF06050.13 KIK70927.1 - 0.0063 16.3 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component DUF3450 PF11932.8 KIK70927.1 - 0.011 15.1 1.7 0.027 13.8 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mod_r PF07200.13 KIK70927.1 - 0.018 15.2 3.5 0.52 10.4 2.8 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5082 PF16888.5 KIK70927.1 - 0.068 13.4 1.7 0.19 12.0 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 KIK70927.1 - 0.12 12.6 4.5 0.22 11.7 4.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF848 PF05852.11 KIK70927.1 - 0.51 10.5 6.4 0.62 10.2 4.0 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_TATA_bd PF12325.8 KIK70927.1 - 1.7 8.9 8.0 10 6.4 0.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SMN PF06003.12 KIK70927.1 - 5.3 6.2 6.3 2.4 7.4 3.6 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Syntaxin-6_N PF09177.11 KIK70927.1 - 8.8 7.0 8.9 5.6 7.6 5.4 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CorA PF01544.18 KIK70928.1 - 6e-18 65.2 3.2 4.2e-12 46.0 0.7 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein TBCC_N PF16752.5 KIK70928.1 - 0.012 16.0 0.1 2.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain RRP36 PF06102.12 KIK70929.1 - 1.4e-39 135.8 20.3 1.9e-39 135.3 20.3 1.2 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 PINIT PF14324.6 KIK70931.1 - 3.7e-34 118.2 1.7 6.1e-34 117.5 1.7 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KIK70931.1 - 5.3e-20 70.9 6.9 1e-19 70.0 6.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KIK70931.1 - 4.2e-08 32.9 1.5 1.1e-07 31.5 1.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KIK70931.1 - 0.018 14.8 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 SAP domain zf-C3HC4_2 PF13923.6 KIK70931.1 - 0.83 9.6 5.8 3.6 7.5 6.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kinesin PF00225.23 KIK70932.1 - 8.1e-104 347.1 0.4 8.1e-104 347.1 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIK70932.1 - 1.9e-59 199.9 0.0 4.7e-59 198.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding MPS2 PF17060.5 KIK70932.1 - 0.4 9.9 13.7 0.26 10.5 11.8 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF1664 PF07889.12 KIK70932.1 - 1 9.4 13.2 1.9 8.6 1.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.6 KIK70932.1 - 2.3 8.2 13.8 0.33 10.9 4.1 2.8 2 0 0 2 2 2 0 FlxA-like protein YscO PF07321.12 KIK70932.1 - 6.7 6.7 30.3 0.15 12.0 9.9 3.4 2 1 0 3 3 3 0 Type III secretion protein YscO Mito_carr PF00153.27 KIK70933.1 - 3.2e-61 203.3 7.0 1.8e-23 82.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.13 KIK70933.1 - 0.17 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 PCRF PF03462.18 KIK70934.1 - 2.2e-44 151.7 2.6 4.6e-44 150.6 0.0 2.1 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KIK70934.1 - 2e-34 118.0 5.4 3.8e-34 117.1 5.4 1.5 1 0 0 1 1 1 1 RF-1 domain ResIII PF04851.15 KIK70935.1 - 1e-19 71.2 0.0 1.8e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK70935.1 - 1.4e-16 60.8 0.1 7.3e-16 58.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK70935.1 - 5.5e-15 55.6 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KIK70935.1 - 3.7e-05 23.1 0.1 6.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 KIK70935.1 - 0.00021 20.1 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain T2SSE PF00437.20 KIK70935.1 - 0.00028 20.0 0.0 0.00062 18.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 KIK70935.1 - 0.00043 20.0 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KIK70935.1 - 0.00069 19.0 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK70935.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 KIK70935.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Indigoidine_A PF04227.12 KIK70936.1 - 4.1e-123 410.4 0.6 6.2e-121 403.2 0.1 2.3 2 0 0 2 2 2 2 Indigoidine synthase A like protein PfkB PF00294.24 KIK70936.1 - 8.6e-28 97.5 0.1 9.6e-15 54.7 0.0 3.0 2 1 0 2 2 2 2 pfkB family carbohydrate kinase MoaE PF02391.17 KIK70937.1 - 3.4e-40 136.9 0.1 4.1e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 MoaE protein ICE2 PF08426.10 KIK70938.1 - 3.6e-23 82.3 12.9 4.2e-16 59.1 15.1 2.2 2 0 0 2 2 2 2 ICE2 Not1 PF04054.15 KIK70938.1 - 0.05 12.5 0.2 0.075 11.9 0.2 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 PGM_PMM_I PF02878.16 KIK70939.1 - 5.4e-16 58.6 0.3 1.6e-06 27.9 0.0 2.7 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KIK70939.1 - 3.7e-11 43.0 0.3 1.4e-10 41.2 0.3 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KIK70939.1 - 0.0017 18.5 0.4 0.005 17.0 0.2 2.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIK70939.1 - 0.025 15.2 0.5 0.4 11.3 0.5 2.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SNAP PF14938.6 KIK70940.1 - 3.9e-107 357.9 13.8 4.5e-107 357.7 13.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KIK70940.1 - 0.012 15.9 11.3 0.55 10.6 2.4 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK70940.1 - 0.078 13.0 6.1 1.8 8.7 0.1 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3486 PF11985.8 KIK70940.1 - 0.15 12.4 1.1 0.31 11.4 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) MscS_porin PF12795.7 KIK70940.1 - 0.19 11.3 1.0 0.96 8.9 0.2 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Spatacsin_C PF14649.6 KIK70940.1 - 0.32 10.1 2.7 1.1 8.3 2.0 1.9 1 1 1 2 2 2 0 Spatacsin C-terminus Prenyltransf PF01255.19 KIK70941.1 - 0.075 12.5 0.0 4.6 6.7 0.0 2.5 3 0 0 3 3 3 0 Putative undecaprenyl diphosphate synthase DUF2235 PF09994.9 KIK70942.1 - 6.8e-73 245.5 0.0 8.8e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) GspH PF12019.8 KIK70942.1 - 0.027 14.9 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II transport protein GspH CS PF04969.16 KIK70944.1 - 5.1e-19 69.1 0.2 8.8e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 CS domain NUC153 PF08159.12 KIK70945.1 - 1.2e-13 50.6 4.4 1.2e-13 50.6 4.4 4.1 4 0 0 4 4 4 3 NUC153 domain SOBP PF15279.6 KIK70946.1 - 0.11 13.1 16.0 0.16 12.6 16.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4758 PF15950.5 KIK70946.1 - 2 8.8 4.5 2.1 8.7 2.7 1.8 2 1 0 2 2 2 0 Putative sperm flagellar membrane protein RRM_1 PF00076.22 KIK70947.1 - 1.5e-40 136.8 0.2 3.8e-20 71.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KIK70947.1 - 5.5e-15 56.2 1.8 2.5e-13 50.9 1.8 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KIK70947.1 - 2.8e-05 24.1 0.3 0.013 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KIK70947.1 - 0.0016 18.2 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIK70947.1 - 0.011 15.7 0.1 3.8 7.6 0.1 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIK70947.1 - 0.044 13.9 0.1 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 KIK70947.1 - 0.058 13.0 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMP1_2 PF08114.11 KIK70948.1 - 0.32 10.8 0.8 0.55 10.0 0.8 1.3 1 0 0 1 1 1 0 ATPase proteolipid family EphA2_TM PF14575.6 KIK70949.1 - 0.073 14.0 0.0 0.22 12.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ras PF00071.22 KIK70950.1 - 1.4e-54 184.1 0.0 1.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK70950.1 - 1e-32 112.9 0.0 1.4e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK70950.1 - 3.1e-13 49.5 0.0 4.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK70950.1 - 4.7e-06 26.3 0.0 0.00017 21.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK70950.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK70950.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KIK70950.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIK70950.1 - 0.0049 16.8 0.0 1.3 8.9 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KIK70950.1 - 0.0051 16.3 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KIK70950.1 - 0.011 15.6 0.0 0.2 11.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KIK70950.1 - 0.011 16.0 0.1 0.021 15.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK70950.1 - 0.011 16.1 0.4 0.04 14.3 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 KIK70950.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 KIK70950.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KIK70950.1 - 0.028 13.8 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KIK70950.1 - 0.032 14.7 0.0 0.061 13.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIK70950.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KIK70950.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIK70950.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 KIK70950.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin D-ser_dehydrat PF14031.6 KIK70951.1 - 6.9e-23 81.1 0.0 2.8e-22 79.2 0.0 2.1 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KIK70951.1 - 3.8e-13 49.6 0.1 5.2e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ribonuc_L-PSP PF01042.21 KIK70952.1 - 8.1e-36 122.7 0.0 9.5e-36 122.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KIK70953.1 - 3.5e-28 98.6 27.1 3.5e-28 98.6 27.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PhoR PF11808.8 KIK70953.1 - 2.2 8.7 5.0 50 4.4 0.0 3.4 2 1 1 3 3 3 0 Phosphate regulon sensor protein PhoR MASE2 PF05230.11 KIK70953.1 - 6.1 7.0 12.2 0.11 12.5 3.2 2.7 3 0 0 3 3 3 0 MASE2 domain Galactosyl_T PF01762.21 KIK70954.1 - 4.4e-07 29.9 0.0 0.0045 16.8 0.0 2.8 2 1 0 2 2 2 2 Galactosyltransferase Cpn60_TCP1 PF00118.24 KIK70955.1 - 2.3e-130 435.5 15.6 6.5e-130 434.0 15.6 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KIK70955.1 - 0.048 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat GST_N_3 PF13417.6 KIK70956.1 - 3.8e-06 27.2 0.0 9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK70956.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK70956.1 - 0.0013 19.0 0.5 0.0069 16.7 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain SGS PF05002.15 KIK70957.1 - 8.6e-34 115.5 2.1 1.3e-33 114.9 2.1 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KIK70957.1 - 9.3e-07 29.8 0.0 1.4e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 CS domain DHFR_1 PF00186.19 KIK70958.1 - 3.2e-29 101.7 0.0 5.7e-29 100.9 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase Ribosomal_L36 PF00444.18 KIK70959.1 - 9.8e-20 70.5 10.9 1.3e-19 70.0 10.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Arc_trans_TRASH PF08394.10 KIK70959.1 - 0.047 14.0 1.3 0.065 13.6 1.3 1.2 1 0 0 1 1 1 0 Archaeal TRASH domain FA_desaturase PF00487.24 KIK70960.1 - 0.022 14.6 0.1 0.022 14.6 0.1 2.5 2 1 1 3 3 3 0 Fatty acid desaturase EamA PF00892.20 KIK70961.1 - 4.5e-08 33.4 40.0 3.2e-07 30.6 4.6 3.7 4 1 0 4 4 4 2 EamA-like transporter family CSG2 PF16965.5 KIK70961.1 - 6.9e-05 22.0 0.2 6.9e-05 22.0 0.2 2.7 2 1 1 3 3 3 1 Ceramide synthase regulator CD34_antigen PF06365.12 KIK70961.1 - 0.046 13.3 0.5 0.078 12.6 0.5 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Metallophos PF00149.28 KIK70962.1 - 7.8e-38 131.0 0.0 3.8e-37 128.8 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK70962.1 - 2.5e-17 63.0 0.0 4.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_S17_N PF16205.5 KIK70963.1 - 1.2e-31 108.9 0.8 2.1e-31 108.1 0.8 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KIK70963.1 - 2.2e-27 95.0 0.5 3.6e-27 94.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DNA_ligase_A_M PF01068.21 KIK70964.1 - 1.2e-64 217.7 0.1 2.1e-64 217.0 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK70964.1 - 3.4e-45 154.5 0.6 3.4e-45 154.5 0.6 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIK70964.1 - 1.6e-25 89.6 0.0 4.4e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 KIK70964.1 - 0.021 14.9 0.1 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Presenilin PF01080.17 KIK70964.1 - 1.3 7.7 2.7 1.9 7.2 2.7 1.2 1 0 0 1 1 1 0 Presenilin Isochorismatase PF00857.20 KIK70965.1 - 4.8e-26 92.0 0.0 1.3e-25 90.6 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family MPC PF03650.13 KIK70966.1 - 1.3e-32 112.2 0.1 1.6e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF908 PF06012.12 KIK70967.1 - 0.11 11.9 0.5 0.17 11.2 0.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) NUDIX PF00293.28 KIK70968.1 - 2.4e-24 85.9 0.0 3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.13 KIK70969.1 - 2.6e-26 91.9 0.0 4.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIK70969.1 - 1.4e-06 27.5 0.0 2.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein BTB PF00651.31 KIK70970.1 - 5.9e-08 32.9 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-CHCC PF10276.9 KIK70971.1 - 6.4e-12 45.3 0.7 9.7e-12 44.7 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.25 KIK70972.1 - 4.2e-50 170.6 0.0 4.1e-49 167.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK70972.1 - 1e-24 87.2 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mgr1 PF08602.10 KIK70972.1 - 0.076 11.8 1.9 0.13 11.1 1.9 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Haspin_kinase PF12330.8 KIK70972.1 - 0.32 9.9 0.0 0.32 9.9 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain NAP PF00956.18 KIK70972.1 - 0.68 9.1 2.0 1.2 8.3 2.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Pribosyltran_N PF13793.6 KIK70973.1 - 2.2e-43 146.9 0.2 9.4e-43 144.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIK70973.1 - 9.6e-38 130.1 1.6 1e-31 110.4 0.4 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIK70973.1 - 9.5e-15 54.5 1.6 1.6e-14 53.7 0.3 1.9 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIK70973.1 - 0.0015 18.0 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF848 PF05852.11 KIK70973.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4611 PF15387.6 KIK70974.1 - 8.5 6.7 7.4 19 5.6 4.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) INCENP_ARK-bind PF03941.15 KIK70975.1 - 1.2e-20 73.1 1.6 1.2e-20 73.1 1.6 2.4 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Corona_NS1 PF06145.11 KIK70975.1 - 0.16 11.5 0.2 0.46 10.1 0.2 1.7 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Ribosomal_S8e PF01201.22 KIK70975.1 - 5.7 7.1 8.9 15 5.8 8.9 1.7 1 0 0 1 1 1 0 Ribosomal protein S8e DCP2 PF05026.13 KIK70976.1 - 2.6e-30 104.5 0.7 4.4e-30 103.8 0.7 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KIK70976.1 - 1.9e-13 50.6 0.0 3.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1658 PF07871.11 KIK70976.1 - 0.53 10.3 4.4 2.3 8.3 4.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) DUF1631 PF07793.11 KIK70976.1 - 2.7 6.3 7.7 3.8 5.8 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AAA_2 PF07724.14 KIK70978.1 - 1e-51 175.4 0.0 4.9e-46 157.0 0.0 3.7 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIK70978.1 - 1e-32 112.1 2.0 1e-32 112.1 2.0 3.4 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 KIK70978.1 - 2e-25 89.7 0.0 2.7e-13 50.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIK70978.1 - 7.4e-23 80.4 0.2 7.4e-23 80.4 0.2 2.6 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KIK70978.1 - 1.2e-21 76.5 3.5 2.6e-13 49.9 1.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KIK70978.1 - 1.3e-14 54.4 0.1 1.3e-07 31.7 0.1 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK70978.1 - 6.5e-13 49.4 2.3 1.9e-05 25.2 0.0 5.0 3 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KIK70978.1 - 3e-09 36.8 0.0 3.8e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KIK70978.1 - 1.2e-08 35.3 0.0 0.0099 16.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIK70978.1 - 1.3e-07 31.5 0.0 0.00042 20.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KIK70978.1 - 6.4e-07 29.3 0.0 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIK70978.1 - 3.8e-06 26.4 0.0 0.0028 17.1 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIK70978.1 - 1.3e-05 25.1 0.0 0.009 15.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.13 KIK70978.1 - 3.8e-05 23.1 1.3 0.029 13.6 0.1 3.1 2 1 1 3 3 3 1 TIP49 P-loop domain RNA_helicase PF00910.22 KIK70978.1 - 7.5e-05 23.1 0.1 0.7 10.3 0.0 3.0 3 0 0 3 3 2 2 RNA helicase TniB PF05621.11 KIK70978.1 - 8.7e-05 22.0 0.0 0.38 10.1 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_18 PF13238.6 KIK70978.1 - 0.00015 22.3 0.0 0.26 11.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIK70978.1 - 0.00015 21.6 0.1 2.1 8.1 0.0 4.2 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIK70978.1 - 0.00027 20.5 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK70978.1 - 0.00028 20.2 0.2 0.046 13.0 0.0 2.9 2 1 1 3 3 3 1 Zeta toxin AAA_33 PF13671.6 KIK70978.1 - 0.00046 20.4 0.0 0.57 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KIK70978.1 - 0.0035 17.6 0.0 0.7 10.1 0.0 3.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 KIK70978.1 - 0.0051 16.9 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Torsin PhoH PF02562.16 KIK70978.1 - 0.0081 15.6 0.0 0.54 9.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 KIK70978.1 - 0.01 16.2 0.0 5.8 7.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KIK70978.1 - 0.01 15.6 0.0 4.6 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KIK70978.1 - 0.015 15.3 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KIK70978.1 - 0.015 15.3 0.0 0.55 10.2 0.0 2.8 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KIK70978.1 - 0.02 15.4 2.4 2.4 8.7 0.0 3.4 4 0 0 4 4 3 0 ABC transporter AAA_3 PF07726.11 KIK70978.1 - 0.021 14.7 0.0 40 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIK70978.1 - 0.026 14.8 2.2 1.9 8.7 0.0 3.4 3 0 0 3 3 2 0 AAA domain Laminin_II PF06009.12 KIK70978.1 - 0.027 14.5 1.7 0.076 13.0 1.7 1.8 1 0 0 1 1 1 0 Laminin Domain II DnaB_C PF03796.15 KIK70978.1 - 0.033 13.5 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Sigma54_activ_2 PF14532.6 KIK70978.1 - 0.044 13.9 0.0 21 5.2 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KIK70978.1 - 0.046 13.6 0.0 4.1 7.3 0.0 3.2 3 0 0 3 3 3 0 NTPase RsgA_GTPase PF03193.16 KIK70978.1 - 0.068 13.1 0.1 4.6 7.1 0.0 2.8 2 1 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 KIK70978.1 - 0.08 13.0 0.1 11 6.1 0.0 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KIK70978.1 - 0.096 12.6 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase ATPase PF06745.13 KIK70978.1 - 0.096 12.0 0.7 3.1 7.1 0.0 3.4 3 1 0 3 3 3 0 KaiC AAA_29 PF13555.6 KIK70978.1 - 0.16 11.7 0.1 11 5.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Atg14 PF10186.9 KIK70978.1 - 0.23 10.5 7.0 0.41 9.7 7.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KIK70978.1 - 0.57 9.7 5.0 1.2 8.6 5.0 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF148 PF02520.17 KIK70978.1 - 1.7 8.8 5.8 17 5.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 Spc7 PF08317.11 KIK70978.1 - 1.8 7.3 13.9 3.3 6.5 13.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_25 PF13481.6 KIK70978.1 - 4.3 6.9 7.4 8.9 5.8 0.0 3.0 3 1 0 3 3 2 0 AAA domain YlqD PF11068.8 KIK70978.1 - 5.1 7.5 7.6 6.4 7.2 6.3 1.9 1 1 0 1 1 1 0 YlqD protein Mg_trans_NIPA PF05653.14 KIK70979.1 - 2.5e-18 66.2 15.6 2.3e-09 36.8 5.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Copper-fist PF00649.18 KIK70980.1 - 5.8e-21 73.7 1.8 5.8e-21 73.7 1.8 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain DENN PF02141.21 KIK70981.1 - 5e-19 69.0 0.0 1.5e-18 67.4 0.0 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain DMPK_coil PF08826.10 KIK70981.1 - 0.048 13.8 4.6 0.17 12.0 4.6 1.9 1 0 0 1 1 1 0 DMPK coiled coil domain like YabA PF06156.13 KIK70981.1 - 0.048 14.3 3.1 7 7.4 0.6 2.9 2 0 0 2 2 2 0 Initiation control protein YabA Lum_binding PF00677.17 KIK70981.1 - 0.059 13.4 1.8 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Lumazine binding domain SOGA PF11365.8 KIK70981.1 - 0.19 12.9 5.4 0.92 10.7 5.4 2.3 1 0 0 1 1 1 0 Protein SOGA APG6_N PF17675.1 KIK70981.1 - 0.41 11.2 10.8 1.5 9.4 10.8 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region Tup_N PF08581.10 KIK70981.1 - 1.9 8.9 5.8 2.2 8.6 3.7 2.2 2 0 0 2 2 2 0 Tup N-terminal OmpH PF03938.14 KIK70981.1 - 2.5 8.5 10.3 1.5 9.2 7.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 KIK70981.1 - 6.6 6.5 8.7 2.8 7.7 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) VPS13_mid_rpt PF16910.5 KIK70982.1 - 4.2e-97 324.2 21.2 4.2e-95 317.7 3.0 5.3 5 1 1 6 6 6 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KIK70982.1 - 2.1e-79 266.6 4.7 2.2e-75 253.5 0.3 3.8 3 0 0 3 3 3 3 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 KIK70982.1 - 1.1e-69 234.9 0.0 5.1e-65 219.5 0.0 2.8 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KIK70982.1 - 1.4e-69 233.4 4.6 5.4e-66 221.8 0.2 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KIK70982.1 - 3.7e-29 101.2 0.1 1.5e-28 99.2 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KIK70982.1 - 1.4e-10 41.4 0.0 1.5e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_transf_25 PF01755.17 KIK70983.1 - 0.0011 18.9 0.4 0.47 10.3 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Tetraspanin PF00335.20 KIK70984.1 - 1 9.0 14.1 3.1 7.4 14.1 1.7 1 1 0 1 1 1 0 Tetraspanin family YrvL PF14184.6 KIK70984.1 - 3 7.9 22.0 0.36 10.9 4.8 3.1 1 1 1 3 3 3 0 Regulatory protein YrvL AA_permease PF00324.21 KIK70986.1 - 3e-143 477.9 41.3 3.6e-143 477.6 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK70986.1 - 1.8e-36 125.9 45.6 2.5e-36 125.5 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease Hep_core_N PF08290.11 KIK70987.1 - 0.013 15.4 2.4 0.36 10.8 0.3 2.6 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger TIR_3 PF18567.1 KIK70987.1 - 0.068 13.2 0.5 0.66 10.0 0.1 2.0 1 1 1 2 2 2 0 Toll/interleukin-1 receptor domain ELO PF01151.18 KIK70988.1 - 5.4e-56 189.9 16.5 6.3e-56 189.7 16.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RasGAP PF00616.19 KIK70989.1 - 6.5e-28 97.9 0.0 2.5e-19 69.8 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KIK70989.1 - 1.4e-12 47.8 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KIK70989.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 PH domain AcylCoA_dehyd_C PF12186.8 KIK70989.1 - 0.97 9.6 4.0 14 5.8 0.0 3.7 4 0 0 4 4 4 0 Acyl-CoA dehydrogenase C terminal Adaptin_N PF01602.20 KIK70990.1 - 1.3e-125 419.9 3.2 6.2e-125 417.7 4.6 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KIK70990.1 - 1.1e-37 128.7 0.0 2.1e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KIK70990.1 - 7.6e-14 52.0 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 KIK70990.1 - 0.047 14.0 0.4 1.6 9.2 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat RTP1_C1 PF10363.9 KIK70990.1 - 0.13 12.4 0.7 0.56 10.4 0.5 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HA2 PF04408.23 KIK70991.1 - 4.9e-17 62.2 0.0 1.4e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK70991.1 - 2e-12 47.4 0.0 5.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK70991.1 - 8.3e-09 35.5 0.1 1.9e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KIK70991.1 - 2.3e-05 25.0 0.0 0.00023 21.8 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_19 PF13245.6 KIK70991.1 - 0.00018 21.9 0.1 0.00072 19.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 KIK70991.1 - 0.00087 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_30 PF13604.6 KIK70991.1 - 0.011 15.5 0.0 0.029 14.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain NRho PF16733.5 KIK70991.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Rhomboid N-terminal domain HSCB_C PF07743.13 KIK70992.1 - 2.1e-16 60.2 5.0 6.5e-16 58.6 4.7 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KIK70992.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain LemA PF04011.12 KIK70992.1 - 0.053 13.4 0.5 0.091 12.6 0.5 1.3 1 0 0 1 1 1 0 LemA family FAM196 PF15265.6 KIK70992.1 - 0.061 12.8 0.1 0.066 12.7 0.1 1.2 1 0 0 1 1 1 0 FAM196 family DUF2508 PF10704.9 KIK70992.1 - 0.27 11.4 3.5 3.4 7.9 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) UPF0547 PF10571.9 KIK70992.1 - 0.69 10.0 8.4 1.1 9.4 8.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF35_N PF12172.8 KIK70992.1 - 2.2 8.2 5.0 4.8 7.2 5.0 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pex24p PF06398.11 KIK70993.1 - 1.4e-07 30.9 1.8 1.4e-07 30.9 1.8 1.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Trs65 PF12735.7 KIK70994.1 - 5.2e-25 88.5 0.5 8.9e-18 64.7 0.5 3.0 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 Aldose_epim PF01263.20 KIK70995.1 - 3e-28 99.0 0.0 3.6e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DNA_pol_B PF00136.21 KIK70996.1 - 1.4e-99 333.9 0.0 2e-99 333.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KIK70996.1 - 2e-24 86.4 0.0 5.5e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KIK70996.1 - 2.8e-13 50.1 2.4 5.2e-13 49.3 2.4 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KIK70996.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral EHN PF06441.12 KIK70996.1 - 0.075 13.4 0.7 0.19 12.1 0.7 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Glyoxalase_3 PF13468.6 KIK70998.1 - 2.7e-28 99.3 0.0 4.2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain DUF5560 PF17715.1 KIK70999.1 - 0.023 14.2 1.7 0.033 13.6 1.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5560) DUF2909 PF11137.8 KIK70999.1 - 0.049 13.6 0.1 0.068 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Mcl1_mid PF12341.8 KIK71000.1 - 3.3e-72 243.4 0.0 7e-71 239.0 0.0 2.8 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KIK71000.1 - 1.2e-17 64.0 10.0 1.8e-05 25.4 0.3 7.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71000.1 - 7.1e-06 26.2 0.0 6.9 7.0 0.0 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ndc1_Nup PF09531.10 KIK71001.1 - 0.055 12.2 2.8 0.11 11.2 2.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 KIK71002.1 - 0.00021 22.0 3.1 0.011 16.6 0.4 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Peptidase_S10 PF00450.22 KIK71004.1 - 7.2e-112 374.9 0.0 1e-111 374.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4335 PF14233.6 KIK71004.1 - 0.13 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) PP2C PF00481.21 KIK71005.1 - 4.1e-23 82.3 0.0 4e-21 75.8 0.0 2.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK71005.1 - 4.6e-06 26.4 0.0 1.9e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIK71005.1 - 0.024 14.5 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) SNF2_N PF00176.23 KIK71006.1 - 5.8e-40 137.1 0.0 1.7e-34 119.1 0.0 2.6 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK71006.1 - 4.9e-09 36.5 0.4 1.4e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RFX5_N PF18326.1 KIK71006.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RFX5 N-terminal domain LemA PF04011.12 KIK71006.1 - 0.8 9.6 2.6 1 9.2 0.3 2.1 2 0 0 2 2 2 0 LemA family SH3_1 PF00018.28 KIK71007.1 - 1.4e-08 34.2 0.0 1.6e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK71007.1 - 5.8e-08 32.5 0.0 6e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK71007.1 - 1.5e-05 24.6 0.0 1.5e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KIK71007.1 - 3.2e-05 24.3 0.0 3.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain PhoLip_ATPase_C PF16212.5 KIK71008.1 - 6e-71 239.1 30.2 6e-71 239.1 30.2 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK71008.1 - 1.2e-19 69.7 0.6 3.6e-19 68.2 0.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KIK71008.1 - 6.2e-13 48.6 0.1 2.9e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK71008.1 - 1.4e-12 48.4 6.1 9.6e-08 32.6 1.3 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIK71008.1 - 6.5e-06 26.1 0.6 0.0021 17.8 0.2 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIK71008.1 - 1.3e-05 24.8 0.0 1.3e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Glyco_hydro_16 PF00722.21 KIK71009.1 - 2.4e-07 30.4 0.0 4.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SurE PF01975.17 KIK71010.1 - 4.7e-47 160.3 0.0 6.6e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_S24e PF01282.19 KIK71011.1 - 4.6e-36 122.6 0.1 9.4e-36 121.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e DUF4870 PF09685.10 KIK71012.1 - 0.0034 17.5 0.5 0.0045 17.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) PsaX PF08078.12 KIK71012.1 - 0.33 10.9 3.3 0.44 10.5 1.1 2.2 1 1 1 2 2 2 0 PsaX family cEGF PF12662.7 KIK71014.1 - 0.28 11.2 0.2 0.28 11.2 0.2 4.0 4 0 0 4 4 4 0 Complement Clr-like EGF-like HEAT PF02985.22 KIK71015.1 - 1.7e-41 136.7 16.9 0.0028 17.8 0.0 14.2 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.6 KIK71015.1 - 1.7e-35 121.2 7.8 8.5e-12 45.3 0.0 7.9 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KIK71015.1 - 1.7e-12 47.8 0.3 0.0071 16.9 0.0 6.5 4 3 4 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KIK71015.1 - 8.3e-11 42.1 12.5 0.25 11.9 0.1 8.8 7 4 4 11 11 11 5 HEAT-like repeat Cnd1 PF12717.7 KIK71015.1 - 1.1e-10 41.8 1.7 0.017 15.1 0.0 5.3 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIK71015.1 - 5e-09 35.2 1.4 0.00015 20.4 0.4 4.3 1 1 1 3 3 3 1 Adaptin N terminal region Arm PF00514.23 KIK71015.1 - 0.00062 19.7 4.9 16 5.7 0.0 6.7 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KIK71015.1 - 0.012 14.9 1.0 2.1 7.5 0.0 3.3 3 1 0 4 4 4 0 V-ATPase subunit H HEAT_PBS PF03130.16 KIK71015.1 - 0.077 13.7 10.3 2.7 8.9 0.6 6.7 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat RRM_1 PF00076.22 KIK71017.1 - 6.1e-30 102.9 0.1 3.8e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK71017.1 - 1.3e-10 41.2 0.1 2.1e-05 24.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK71017.1 - 0.00059 19.8 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif UPF0160 PF03690.13 KIK71018.1 - 1.3e-133 445.6 0.0 1.4e-133 445.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) MARVEL PF01284.23 KIK71019.1 - 0.00021 21.3 11.5 0.0003 20.8 11.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.16 KIK71020.1 - 1.4e-21 76.8 22.0 1.4e-21 76.8 22.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily SOG2 PF10428.9 KIK71022.1 - 1.9 7.6 15.2 2.2 7.4 15.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 KIK71022.1 - 9.5 4.7 11.2 11 4.5 11.2 1.0 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.14 KIK71023.1 - 2e-76 257.8 10.7 2.2e-75 254.4 0.0 4.1 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KIK71023.1 - 5.4e-10 39.3 4.0 0.0075 17.0 0.1 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK71023.1 - 1.3e-05 25.6 1.1 1.5 9.4 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK71023.1 - 0.00025 21.6 2.3 0.18 12.5 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KIK71023.1 - 0.0076 15.4 7.4 0.13 11.4 2.3 4.2 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 KIK71023.1 - 0.01 15.1 9.2 0.37 9.9 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK71023.1 - 0.094 13.4 0.7 2.9 8.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HAUS6_N PF14661.6 KIK71023.1 - 0.28 10.7 2.9 11 5.5 0.0 2.9 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus RasGEF PF00617.19 KIK71024.1 - 2.8e-33 115.6 0.1 5e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK71024.1 - 1.5e-09 38.0 0.0 4.3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KIK71024.1 - 0.00046 19.8 0.0 0.004 16.8 0.0 2.2 2 0 0 2 2 2 1 Ras family Viral_helicase1 PF01443.18 KIK71024.1 - 0.068 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KIK71025.1 - 6e-48 162.9 0.0 2.2e-47 161.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK71025.1 - 2.1e-30 105.3 0.1 4.4e-28 97.8 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK71025.1 - 0.18 12.0 1.3 1.5 9.1 0.1 2.9 2 2 0 2 2 2 0 AAA domain Trypan_PARP PF05887.11 KIK71025.1 - 2.9 7.9 6.5 7.7 6.5 6.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SVIP PF15811.5 KIK71026.1 - 0.00083 19.8 1.4 0.0012 19.3 1.4 1.4 1 1 0 1 1 1 1 Small VCP/p97-interacting protein DUF2607 PF10795.9 KIK71026.1 - 0.18 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) GPI2 PF06432.11 KIK71027.1 - 2.1e-85 286.6 14.9 2.4e-85 286.4 14.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase bZIP_1 PF00170.21 KIK71028.1 - 6.2e-05 23.0 7.1 0.00018 21.5 6.2 2.0 1 1 1 2 2 2 1 bZIP transcription factor GIT_CC PF16559.5 KIK71028.1 - 0.00085 19.1 2.3 0.0015 18.3 2.3 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor BST2 PF16716.5 KIK71028.1 - 0.00095 19.7 3.2 0.0038 17.8 3.4 1.8 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 SlyX PF04102.12 KIK71028.1 - 0.003 18.1 2.1 0.0062 17.1 2.1 1.5 1 0 0 1 1 1 1 SlyX YabA PF06156.13 KIK71028.1 - 0.012 16.2 0.2 0.019 15.6 0.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Lzipper-MIP1 PF14389.6 KIK71028.1 - 0.013 15.8 0.9 1.1 9.6 0.2 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.11 KIK71028.1 - 0.013 15.7 5.0 0.013 15.7 5.0 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 KIK71028.1 - 0.021 14.9 12.4 0.19 11.8 3.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Prefoldin_2 PF01920.20 KIK71028.1 - 0.022 14.7 1.0 0.047 13.7 1.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit SIKE PF05769.11 KIK71028.1 - 0.043 13.7 1.4 0.071 13.0 1.4 1.3 1 0 0 1 1 1 0 SIKE family Fib_alpha PF08702.10 KIK71028.1 - 0.1 12.8 5.2 0.039 14.1 2.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_lid_2 PF17863.1 KIK71028.1 - 0.11 12.3 1.7 0.26 11.2 0.4 2.1 2 0 0 2 2 2 0 AAA lid domain DUF3523 PF12037.8 KIK71028.1 - 0.17 11.2 4.6 0.27 10.6 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) PI3K_P85_iSH2 PF16454.5 KIK71028.1 - 0.21 11.2 4.9 3 7.4 1.2 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Med11 PF10280.9 KIK71028.1 - 0.21 12.0 2.9 0.39 11.2 2.7 1.6 1 1 0 1 1 1 0 Mediator complex protein Prominin PF05478.11 KIK71028.1 - 0.29 9.0 0.6 0.4 8.6 0.6 1.1 1 0 0 1 1 1 0 Prominin DUF2333 PF10095.9 KIK71028.1 - 0.67 8.9 5.1 0.38 9.7 2.7 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) bZIP_Maf PF03131.17 KIK71028.1 - 1 9.9 7.5 1.7 9.2 6.6 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor ANAPC4 PF12896.7 KIK71029.1 - 2e-43 148.3 0.3 3.3e-43 147.6 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KIK71029.1 - 4e-09 36.7 0.0 1.6e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71029.1 - 0.033 14.1 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF3373 PF11853.8 KIK71030.1 - 0.19 10.8 0.3 0.25 10.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Actin PF00022.19 KIK71031.1 - 2e-125 418.6 0.0 3.7e-100 335.4 0.0 2.7 2 1 0 2 2 2 2 Actin DUF2304 PF10066.9 KIK71032.1 - 0.0047 17.1 3.0 0.0051 17.0 3.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2304) SAD_SRA PF02182.17 KIK71034.1 - 6.6e-53 178.6 0.0 1.1e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain V-SNARE_C PF12352.8 KIK71035.1 - 0.00028 21.1 7.8 0.18 12.1 1.1 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.12 KIK71035.1 - 0.84 9.6 7.6 4.2 7.4 0.2 2.6 2 1 0 2 2 2 0 Laminin Domain II Mpp10 PF04006.12 KIK71036.1 - 6.6e-111 371.7 58.5 1.4e-110 370.6 58.4 1.4 1 1 0 1 1 1 1 Mpp10 protein Metal_resist PF13801.6 KIK71036.1 - 6.6 6.9 8.7 4.4 7.5 1.4 2.7 3 0 0 3 3 3 0 Heavy-metal resistance Ribosomal_S3_C PF00189.20 KIK71037.1 - 9.2e-23 80.6 0.3 3.4e-22 78.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KIK71037.1 - 6.5e-12 45.1 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KIK71037.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 WD40 PF00400.32 KIK71038.1 - 5.3e-08 33.4 0.8 1.2 10.2 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71038.1 - 0.036 14.4 0.1 0.43 10.9 0.0 2.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK71038.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NINJA_B PF16136.5 KIK71038.1 - 6.6 7.2 14.2 0.042 14.2 4.4 2.4 3 0 0 3 3 3 0 Putative nuclear localisation signal DUF2208 PF09973.9 KIK71039.1 - 0.014 15.0 1.3 0.014 15.0 1.3 1.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) DUF4006 PF13179.6 KIK71039.1 - 0.2 11.6 1.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) GldM_N PF12081.8 KIK71039.1 - 0.28 11.3 0.0 0.42 10.7 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Pox_I1 PF03289.13 KIK71040.1 - 0.017 14.3 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus protein I1 Mto2_bdg PF12808.7 KIK71040.1 - 0.029 14.7 0.3 0.029 14.7 0.3 4.5 5 0 0 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 KIK71040.1 - 3.1 8.0 14.7 1.5 9.0 0.4 4.4 3 0 0 3 3 3 0 Basic region leucine zipper DUF1664 PF07889.12 KIK71040.1 - 4 7.5 15.2 25 4.9 0.3 6.0 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) HALZ PF02183.18 KIK71040.1 - 8.3 6.7 12.4 5.8 7.2 0.2 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper HABP4_PAI-RBP1 PF04774.15 KIK71041.1 - 2.2e-09 38.2 14.0 2.2e-09 38.2 14.0 2.2 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family PHD PF00628.29 KIK71042.1 - 2e-10 40.4 9.1 2e-10 40.4 9.1 2.0 2 0 0 2 2 2 1 PHD-finger zf-ZPR1 PF03367.13 KIK71042.1 - 0.43 10.4 2.6 0.56 10.0 1.1 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain C1_1 PF00130.22 KIK71042.1 - 0.52 10.2 2.4 1.3 8.9 2.4 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SlyX PF04102.12 KIK71042.1 - 0.81 10.4 4.7 0.93 10.2 0.5 3.0 2 0 0 2 2 2 0 SlyX LSM PF01423.22 KIK71043.1 - 1.7e-18 66.0 0.2 2.6e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK71043.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Ribosomal_L32p PF01783.23 KIK71044.1 - 4.6e-16 58.8 3.4 5.8e-16 58.5 3.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 KIK71044.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbons Prok-RING_1 PF14446.6 KIK71044.1 - 0.041 13.8 4.4 0.37 10.8 4.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_7 PF02591.15 KIK71044.1 - 0.1 12.8 0.7 0.66 10.2 0.0 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 KIK71044.1 - 0.18 11.9 2.5 1.6 8.9 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain ETC_C1_NDUFA5 PF04716.14 KIK71045.1 - 4.1e-25 87.4 0.5 1.5e-24 85.5 0.1 1.8 2 0 0 2 2 2 1 ETC complex I subunit conserved region Thiolase_N PF00108.23 KIK71046.1 - 2.1e-67 227.3 0.1 3.3e-67 226.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK71046.1 - 8.6e-42 141.7 0.2 1.8e-41 140.6 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK71046.1 - 0.0026 17.4 1.6 0.1 12.1 0.1 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK71046.1 - 0.013 15.3 0.1 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KIK71046.1 - 0.032 14.4 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal His_Phos_1 PF00300.22 KIK71047.1 - 2.5e-23 82.8 0.0 3.5e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GMC_oxred_N PF00732.19 KIK71049.1 - 3.3e-63 213.8 0.0 4.6e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK71049.1 - 5.3e-40 137.3 0.0 9.6e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK71049.1 - 0.00044 20.4 0.2 0.0013 18.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK71049.1 - 0.0038 16.5 0.0 2.8 7.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK71049.1 - 0.006 15.7 0.2 2.1 7.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK71049.1 - 0.0061 15.6 0.1 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK71049.1 - 0.037 13.3 0.1 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase His_Phos_1 PF00300.22 KIK71050.1 - 9.4e-21 74.4 0.0 1.5e-20 73.7 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Secretin_N PF03958.17 KIK71050.1 - 0.15 12.5 0.0 2.2 8.8 0.0 2.2 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Memo PF01875.17 KIK71051.1 - 5.6e-72 242.1 0.0 6.7e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MotY_N PF18393.1 KIK71051.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 MotY N-terminal domain Ribosomal_L32e PF01655.18 KIK71052.1 - 5.5e-52 174.7 0.8 6.4e-52 174.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.25 KIK71053.1 - 1.8e-39 135.7 0.0 1.1e-37 129.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71053.1 - 1.1e-14 54.3 0.0 5.4e-13 48.8 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK71053.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK71053.1 - 0.0036 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK71053.1 - 0.016 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK71053.1 - 0.24 11.0 0.0 0.61 9.7 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GTP_EFTU PF00009.27 KIK71054.1 - 1.3e-53 181.5 0.0 2.5e-53 180.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK71054.1 - 1.2e-42 144.7 0.0 3.2e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIK71054.1 - 4.5e-14 52.6 2.7 5.2e-14 52.4 1.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK71054.1 - 0.0013 18.8 0.1 0.036 14.1 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KIK71054.1 - 0.031 14.2 0.8 0.11 12.4 0.8 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 KIK71054.1 - 0.042 13.9 0.1 0.51 10.4 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain NIF3 PF01784.18 KIK71054.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DLH PF01738.18 KIK71055.1 - 1.7e-24 86.6 0.0 2.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KIK71055.1 - 0.0062 16.1 0.0 0.0084 15.7 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 KIK71055.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2048 PF09752.9 KIK71055.1 - 0.071 12.2 0.1 0.14 11.2 0.1 1.4 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Acetyltransf_1 PF00583.25 KIK71056.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KIK71056.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KIK71056.1 - 0.029 14.8 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK71056.1 - 0.033 14.1 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Elong_Iki1 PF10483.9 KIK71057.1 - 2.6e-11 43.6 0.2 1.1e-10 41.5 0.2 1.9 1 1 0 1 1 1 1 Elongator subunit Iki1 Aminotran_1_2 PF00155.21 KIK71059.1 - 7.8e-88 295.1 0.0 8.9e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 KIK71060.1 - 2.3e-76 256.9 0.0 3.3e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK71060.1 - 8.4e-07 28.9 0.1 1.6e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIK71060.1 - 0.022 14.2 1.0 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.10 KIK71060.1 - 0.05 13.7 3.2 0.089 12.9 3.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AUX_IAA PF02309.16 KIK71060.1 - 0.36 10.7 5.0 0.82 9.5 0.0 2.5 3 0 0 3 3 3 0 AUX/IAA family RNA_pol_Rpc4 PF05132.14 KIK71060.1 - 1.8 9.0 8.0 3 8.3 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Herpes_gE PF02480.16 KIK71061.1 - 0.033 13.0 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MAP17 PF15807.5 KIK71061.1 - 0.11 12.8 0.6 0.17 12.2 0.2 1.6 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FixQ PF05545.11 KIK71061.1 - 0.43 10.6 2.4 0.69 9.9 2.4 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF4131 PF13567.6 KIK71061.1 - 3.1 7.4 4.5 4.7 6.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SPRY PF00622.28 KIK71062.1 - 2e-21 76.3 0.0 3.1e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain FAM101 PF15068.6 KIK71062.1 - 2.8 7.8 6.1 1.7 8.5 0.5 2.2 1 1 1 2 2 2 0 FAM101 family CBS PF00571.28 KIK71063.1 - 5.7e-22 77.9 2.7 2.8e-11 43.7 0.1 4.4 4 0 0 4 4 4 4 CBS domain UL45 PF05473.12 KIK71063.1 - 0.071 12.7 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like PX PF00787.24 KIK71064.1 - 5.2e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 PX domain Methyltransf_23 PF13489.6 KIK71064.1 - 7.7e-10 38.8 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK71064.1 - 1.4e-05 25.7 0.0 2.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK71064.1 - 0.00014 22.5 0.0 0.00046 20.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK71064.1 - 0.00039 21.0 0.0 0.0012 19.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK71064.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fez1 PF06818.15 KIK71064.1 - 0.018 15.5 0.1 0.033 14.6 0.1 1.4 1 1 0 1 1 1 0 Fez1 EzrA PF06160.12 KIK71064.1 - 0.1 10.7 0.1 0.3 9.2 0.0 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA NUC202 PF08166.12 KIK71064.1 - 0.19 11.8 0.4 0.63 10.2 0.1 2.0 2 0 0 2 2 2 0 NUC202 domain Nucleoporin_FG PF13634.6 KIK71064.1 - 0.8 10.6 2.4 1.4 9.8 2.4 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Mito_carr PF00153.27 KIK71065.1 - 5.8e-54 180.0 0.8 3.4e-19 68.5 0.1 3.6 2 2 1 3 3 3 3 Mitochondrial carrier protein Pil1 PF13805.6 KIK71066.1 - 1e-46 159.6 0.1 1.6e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 SMN PF06003.12 KIK71069.1 - 2.9e-12 46.4 4.2 3.7e-12 46.1 4.2 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KIK71069.1 - 2.6e-06 27.5 0.0 1.4e-05 25.1 0.0 2.0 1 1 1 2 2 2 1 Tudor domain Tudor_3 PF18115.1 KIK71069.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 KIK71069.1 - 0.0098 16.3 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Agenet domain Dot_icm_IcmQ PF09475.10 KIK71069.1 - 0.031 13.8 0.2 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUF1325 PF07039.11 KIK71069.1 - 0.078 13.1 0.1 0.078 13.1 0.1 2.4 2 1 0 2 2 2 0 SGF29 tudor-like domain DUF4537 PF15057.6 KIK71069.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KIK71069.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF5308 PF17233.2 KIK71069.1 - 0.29 11.3 7.2 1.6 9.0 0.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Jak1_Phl PF17887.1 KIK71069.1 - 0.34 10.9 4.9 0.13 12.3 2.0 1.8 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain PWWP PF00855.17 KIK71069.1 - 0.66 10.4 6.2 0.53 10.7 3.2 2.4 2 1 0 2 2 2 0 PWWP domain PDCD2_C PF04194.13 KIK71069.1 - 3 7.9 9.7 1.4 8.9 4.8 2.0 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Mito_fiss_reg PF05308.11 KIK71069.1 - 7.1 6.6 10.8 34 4.4 10.8 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator RIO1 PF01163.22 KIK71070.1 - 4e-43 147.2 0.0 6.2e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KIK71070.1 - 2.1e-33 114.4 0.0 4.3e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KIK71070.1 - 3.1e-10 40.4 0.1 7e-05 22.9 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIK71070.1 - 2.5e-07 30.3 0.0 1.3e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TrmB PF01978.19 KIK71070.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Acetyltransf_1 PF00583.25 KIK71071.1 - 3.8e-14 52.9 0.0 5.6e-14 52.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK71071.1 - 4.4e-08 33.1 0.0 6.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK71071.1 - 5e-08 33.3 0.0 7.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK71071.1 - 4.7e-06 26.8 0.0 6.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK71071.1 - 3.8e-05 23.6 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIK71071.1 - 0.011 16.4 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Alpha-amylase PF00128.24 KIK71072.1 - 9.9e-19 68.1 1.5 9.9e-19 68.1 1.5 2.9 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KIK71072.1 - 5.8e-15 55.6 0.0 1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIK71072.1 - 1.8e-07 30.9 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 ESSS PF10183.9 KIK71073.1 - 2.5e-12 46.9 0.1 2.7e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GCV_H PF01597.19 KIK71074.1 - 2.9e-40 136.9 0.2 3.4e-40 136.7 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KIK71074.1 - 9.9e-05 22.1 0.2 0.00018 21.2 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 KIK71074.1 - 0.00067 19.6 1.4 0.001 19.0 1.4 1.3 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GTP_EFTU PF00009.27 KIK71075.1 - 1.5e-56 191.1 1.0 2.2e-56 190.5 1.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK71075.1 - 5.2e-27 94.4 0.1 1.3e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIK71075.1 - 4.7e-18 65.4 1.2 1.2e-17 64.0 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK71075.1 - 4.1e-05 23.6 0.1 6.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK71075.1 - 0.0011 19.0 0.1 0.0021 18.0 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KIK71075.1 - 0.0045 16.6 1.0 0.0065 16.1 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KIK71075.1 - 0.01 15.6 0.7 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pex14_N PF04695.13 KIK71076.1 - 2.5e-21 77.0 2.7 2.1e-14 54.5 0.1 3.6 2 2 1 3 3 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT57 PF10498.9 KIK71076.1 - 0.00028 20.0 9.1 0.00068 18.7 9.1 1.5 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KIK71076.1 - 0.0022 17.5 9.5 0.0034 16.9 9.5 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Laminin_II PF06009.12 KIK71076.1 - 0.0034 17.4 9.2 0.0067 16.4 9.2 1.4 1 0 0 1 1 1 1 Laminin Domain II DUF4407 PF14362.6 KIK71076.1 - 0.0034 16.8 1.9 0.0049 16.3 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Spc7 PF08317.11 KIK71076.1 - 0.0058 15.6 10.7 0.0087 15.0 10.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-C4H2 PF10146.9 KIK71076.1 - 0.006 16.9 2.3 0.0093 16.3 2.3 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein FIVAR PF07554.13 KIK71076.1 - 0.0071 17.1 4.4 0.082 13.7 3.3 2.4 2 0 0 2 2 2 1 FIVAR domain TTKRSYEDQ PF10212.9 KIK71076.1 - 0.01 14.9 1.3 0.015 14.3 1.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF3584 PF12128.8 KIK71076.1 - 0.013 13.0 11.7 0.018 12.6 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3829 PF12889.7 KIK71076.1 - 0.019 14.5 5.2 0.026 14.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) AIP3 PF03915.13 KIK71076.1 - 0.024 13.7 6.0 0.033 13.3 6.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 ING PF12998.7 KIK71076.1 - 0.029 15.0 6.0 0.029 14.9 4.5 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding BshC PF10079.9 KIK71076.1 - 0.033 12.9 4.4 0.052 12.3 4.4 1.4 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC LMBR1 PF04791.16 KIK71076.1 - 0.037 12.9 1.4 0.046 12.6 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EzrA PF06160.12 KIK71076.1 - 0.041 12.1 7.7 0.072 11.3 7.7 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 KIK71076.1 - 0.043 12.9 0.4 0.064 12.3 0.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 KIK71076.1 - 0.048 13.7 6.0 0.21 11.7 5.9 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Pox_F16 PF04708.12 KIK71076.1 - 0.058 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein Baculo_PEP_C PF04513.12 KIK71076.1 - 0.059 13.4 2.4 0.13 12.3 2.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KIK71076.1 - 0.061 13.8 11.9 0.77 10.3 2.0 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 KIK71076.1 - 0.065 11.2 0.0 0.07 11.0 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 KIK71076.1 - 0.071 11.7 4.7 0.1 11.3 4.7 1.1 1 0 0 1 1 1 0 AAA domain LXG PF04740.12 KIK71076.1 - 0.078 12.7 7.4 0.12 12.0 7.4 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Tektin PF03148.14 KIK71076.1 - 0.14 10.9 13.2 0.32 9.7 13.2 1.5 1 1 0 1 1 1 0 Tektin family UPF0242 PF06785.11 KIK71076.1 - 0.18 11.9 5.2 0.31 11.1 5.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PSK_trans_fac PF07704.11 KIK71076.1 - 0.26 12.1 8.5 0.49 11.2 7.9 1.8 1 1 0 1 1 1 0 Rv0623-like transcription factor Phage_holin_7_1 PF16081.5 KIK71076.1 - 0.26 11.5 3.6 1.2 9.3 3.2 2.2 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MscS_porin PF12795.7 KIK71076.1 - 0.28 10.7 13.3 1 8.8 5.5 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Med21 PF11221.8 KIK71076.1 - 0.28 11.4 10.5 1.7 8.9 1.1 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex ISG65-75 PF11727.8 KIK71076.1 - 0.28 10.4 7.6 0.5 9.6 7.6 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Zw10 PF06248.13 KIK71076.1 - 0.31 9.6 7.6 0.43 9.1 7.6 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Fib_alpha PF08702.10 KIK71076.1 - 0.31 11.2 7.7 0.55 10.4 7.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KIK71076.1 - 0.32 10.2 5.7 0.56 9.4 5.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF1319 PF07028.11 KIK71076.1 - 0.4 10.9 5.6 1.3 9.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF1664 PF07889.12 KIK71076.1 - 0.4 10.7 12.3 0.27 11.3 2.8 2.7 1 1 2 3 3 2 0 Protein of unknown function (DUF1664) TssO PF17561.2 KIK71076.1 - 0.41 10.7 2.8 0.67 10.0 2.8 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO Apolipoprotein PF01442.18 KIK71076.1 - 0.45 10.4 17.2 0.58 10.0 15.4 2.0 2 1 0 2 2 1 0 Apolipoprotein A1/A4/E domain FlgN PF05130.12 KIK71076.1 - 0.56 10.7 10.3 0.98 9.9 10.3 1.3 1 0 0 1 1 1 0 FlgN protein Fez1 PF06818.15 KIK71076.1 - 0.57 10.6 8.9 0.85 10.0 8.9 1.2 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 KIK71076.1 - 0.59 10.2 13.2 1.4 9.0 12.8 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1043 PF06295.12 KIK71076.1 - 0.8 9.7 4.2 4.9 7.2 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Prominin PF05478.11 KIK71076.1 - 0.86 7.5 2.8 1.1 7.1 2.8 1.1 1 0 0 1 1 1 0 Prominin SOAR PF16533.5 KIK71076.1 - 0.86 9.6 6.1 1.6 8.8 6.1 1.5 1 0 0 1 1 1 0 STIM1 Orai1-activating region CorA PF01544.18 KIK71076.1 - 1.1 8.6 6.9 2.6 7.3 1.6 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KIK71076.1 - 1.1 9.8 13.9 2.2 8.8 13.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region COG2 PF06148.11 KIK71076.1 - 1.2 9.3 12.2 0.75 9.9 6.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2849 PF11011.8 KIK71076.1 - 1.2 9.9 4.9 2.9 8.6 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) USP8_interact PF08941.10 KIK71076.1 - 1.4 8.7 4.3 3 7.6 4.3 1.6 1 1 0 1 1 1 0 USP8 interacting Baculo_p24 PF05073.12 KIK71076.1 - 1.8 8.3 5.1 4.4 7.0 5.2 1.6 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF948 PF06103.11 KIK71076.1 - 2 8.7 9.2 4 7.8 5.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rsd_AlgQ PF04353.13 KIK71076.1 - 2.2 8.2 7.1 0.41 10.6 1.8 2.0 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF3450 PF11932.8 KIK71076.1 - 2.5 7.3 12.7 4.4 6.5 11.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KIK71076.1 - 2.5 8.5 14.5 0.59 10.5 6.4 2.4 1 1 0 2 2 2 0 Csm1 N-terminal domain DLP_helical PF18709.1 KIK71076.1 - 2.6 7.2 9.2 5.9 6.0 9.3 1.5 1 1 0 1 1 1 0 Dynamin-like helical domain HAUS-augmin3 PF14932.6 KIK71076.1 - 2.8 7.5 10.1 4 7.0 10.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KIK71076.1 - 2.8 8.6 9.7 8.7 7.0 2.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Mitofilin PF09731.9 KIK71076.1 - 2.9 6.6 16.4 20 3.9 16.5 1.7 1 1 0 1 1 1 0 Mitochondrial inner membrane protein KxDL PF10241.9 KIK71076.1 - 3.3 8.1 9.3 0.53 10.6 0.8 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein THOC7 PF05615.13 KIK71076.1 - 3.7 7.8 12.8 19 5.6 12.8 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 SlyX PF04102.12 KIK71076.1 - 5 7.8 9.5 79 4.0 0.2 3.3 2 1 2 4 4 3 0 SlyX TBCC_N PF16752.5 KIK71076.1 - 5.6 7.4 11.4 13 6.2 9.0 2.3 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HisKA_3 PF07730.13 KIK71076.1 - 5.6 7.6 8.5 21 5.7 5.2 2.9 1 1 1 2 2 2 0 Histidine kinase LCIB_C_CA PF18599.1 KIK71076.1 - 6.3 6.0 5.4 9.9 5.4 5.4 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CC2-LZ PF16516.5 KIK71076.1 - 7.1 7.1 13.8 4.6e+02 1.3 13.7 2.4 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2203 PF09969.9 KIK71076.1 - 7.6 7.3 8.7 27 5.5 8.7 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 KIK71076.1 - 8.1 6.9 10.3 14 6.1 2.8 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Mt_ATP-synt_D PF05873.12 KIK71076.1 - 9.1 6.1 10.3 7.4 6.4 5.1 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GRIP PF01465.20 KIK71077.1 - 5.7e-17 61.3 1.4 2.9e-16 59.1 0.6 2.5 2 0 0 2 2 2 1 GRIP domain DUF812 PF05667.11 KIK71077.1 - 0.02 13.8 80.4 0.015 14.2 17.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Glutaredoxin2_C PF04399.13 KIK71077.1 - 8.5 6.2 11.0 0.63 9.9 0.1 3.7 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Med5 PF08689.10 KIK71078.1 - 5.7e-10 37.7 1.1 1.4e-09 36.5 0.1 2.1 3 0 0 3 3 3 1 Mediator complex subunit Med5 Cation_efflux PF01545.21 KIK71079.1 - 1e-52 178.8 4.6 1.5e-52 178.2 4.6 1.3 1 0 0 1 1 1 1 Cation efflux family MASE4 PF17158.4 KIK71079.1 - 0.0035 16.6 3.6 0.0068 15.7 3.6 1.5 1 0 0 1 1 1 1 Membrane-associated sensor, integral membrane domain JAB PF01398.21 KIK71080.1 - 1.5e-12 47.5 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DPBB_1 PF03330.18 KIK71081.1 - 3.5e-10 40.0 0.0 6.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KIK71081.1 - 0.052 13.7 0.1 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 Cerato-platanin PARM PF17061.5 KIK71081.1 - 0.095 12.8 23.5 0.13 12.3 23.5 1.2 1 0 0 1 1 1 0 PARM SOG2 PF10428.9 KIK71081.1 - 3.2 6.8 17.2 3.8 6.6 17.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 KIK71081.1 - 4 6.2 6.5 4.8 5.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ipi1_N PF12333.8 KIK71082.1 - 4.1e-20 72.3 0.0 2.4e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Cellulase PF00150.18 KIK71083.1 - 8.1e-17 61.6 4.2 1.8e-16 60.4 4.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KIK71083.1 - 0.0016 18.1 1.0 0.0021 17.8 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KIK71083.1 - 0.0025 17.0 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KIK71083.1 - 0.023 14.1 0.1 0.066 12.5 0.1 1.7 1 1 0 1 1 1 0 Beta-galactosidase DIM PF08194.12 KIK71083.1 - 0.089 13.0 1.0 0.16 12.2 1.0 1.4 1 0 0 1 1 1 0 DIM protein E1_DerP2_DerF2 PF02221.15 KIK71085.1 - 1.4e-24 87.0 0.1 1.7e-24 86.8 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KIK71085.1 - 0.006 16.9 0.0 0.0079 16.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Tetraspanin PF00335.20 KIK71086.1 - 0.0029 17.4 2.6 0.0029 17.4 2.6 1.4 1 1 0 1 1 1 1 Tetraspanin family Ribosomal_L17 PF01196.19 KIK71090.1 - 4.5e-35 120.4 0.0 1.1e-34 119.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 PP-binding PF00550.25 KIK71091.1 - 2.3e-13 50.3 0.7 3.2e-13 49.8 0.7 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KIK71091.1 - 5.1e-07 29.8 0.6 6.8e-07 29.4 0.6 1.2 1 0 0 1 1 1 1 Acyl-carrier SGL PF08450.12 KIK71092.1 - 2.4e-67 227.1 0.0 2.9e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIK71092.1 - 5.8e-05 23.2 0.0 0.00054 20.1 0.0 2.3 3 0 0 3 3 3 1 Arylesterase PD40 PF07676.12 KIK71092.1 - 0.012 15.5 0.5 0.049 13.6 0.4 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Str_synth PF03088.16 KIK71092.1 - 0.059 13.5 0.0 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase Ribosomal_L13 PF00572.18 KIK71093.1 - 2e-11 44.2 0.0 1.1e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L13 KH_1 PF00013.29 KIK71094.1 - 1.2e-40 137.1 9.7 1.7e-15 56.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIK71094.1 - 4.9e-12 45.6 0.0 0.00084 19.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIK71094.1 - 8.4e-08 31.9 5.8 0.045 13.6 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KIK71094.1 - 0.00011 22.2 4.5 0.11 12.7 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 KIK71094.1 - 0.006 16.3 0.4 0.6 9.8 0.1 2.5 2 0 0 2 2 2 1 dUTPase NUFIP1 PF10453.9 KIK71095.1 - 7.1e-14 51.4 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Peptidase_M16_C PF05193.21 KIK71096.1 - 4.2e-16 59.5 0.0 4.8e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIK71096.1 - 7.5e-10 39.0 0.1 1.3e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2205 PF10224.9 KIK71096.1 - 0.0093 15.9 0.6 0.04 13.9 0.6 2.1 1 0 0 1 1 1 1 Short coiled-coil protein RQC PF09382.10 KIK71096.1 - 0.015 15.1 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 RQC domain M16C_assoc PF08367.11 KIK71096.1 - 0.028 13.6 2.7 0.75 8.9 2.2 2.5 2 0 0 2 2 2 0 Peptidase M16C associated Cluap1 PF10234.9 KIK71096.1 - 0.094 12.1 0.4 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF1823 PF08853.11 KIK71096.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Troponin PF00992.20 KIK71096.1 - 0.14 12.4 4.0 0.25 11.6 0.0 2.7 3 0 0 3 3 3 0 Troponin Exo_endo_phos PF03372.23 KIK71097.1 - 2e-19 70.0 0.0 4.4e-19 68.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 KIK71098.1 - 2.2e-18 67.2 0.0 3.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Fungal_trans PF04082.18 KIK71100.1 - 8.2e-09 34.9 0.1 1.4e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK71100.1 - 1.7e-06 28.0 11.9 4e-06 26.9 11.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0047 PF01894.17 KIK71101.1 - 2.9e-33 114.4 0.0 1e-32 112.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CCCH PF00642.24 KIK71102.1 - 7.3e-19 67.2 22.5 2.5e-05 24.1 0.6 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK71102.1 - 4.6e-13 48.7 29.1 1e-06 28.6 2.1 4.8 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KIK71102.1 - 6e-08 33.3 23.0 0.00099 19.8 0.5 5.1 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KIK71102.1 - 2.4e-05 24.0 0.4 2.4e-05 24.0 0.4 4.8 6 0 0 6 6 6 1 CCCH-type zinc finger zf-CCHC PF00098.23 KIK71102.1 - 0.00036 20.5 3.7 0.00036 20.5 3.7 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 KIK71102.1 - 0.0027 18.1 0.5 0.0027 18.1 0.5 5.4 6 0 0 6 6 6 3 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 KIK71102.1 - 0.0056 16.6 0.2 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIK71102.1 - 0.053 13.4 3.1 0.24 11.2 3.1 2.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_3 PF15663.5 KIK71102.1 - 1.4 9.2 15.7 2.7 8.3 0.4 3.9 1 1 3 4 4 4 0 Zinc-finger containing family p450 PF00067.22 KIK71103.1 - 4.2e-58 197.2 0.0 6e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stealth_CR4 PF17103.5 KIK71103.1 - 0.055 13.4 0.2 5.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Strep_pep PF14404.6 KIK71103.1 - 0.13 12.6 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species PDT PF00800.18 KIK71104.1 - 3e-54 183.6 0.0 3.7e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Fungal_trans PF04082.18 KIK71105.1 - 1.4e-13 50.5 0.1 2.8e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK71105.1 - 7e-05 22.9 8.9 0.00013 22.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKcGMP_CC PF16808.5 KIK71105.1 - 0.25 11.2 1.5 0.5 10.3 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Requiem_N PF14051.6 KIK71106.1 - 0.033 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Ras PF00071.22 KIK71107.1 - 1.7e-54 183.8 0.0 1.9e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK71107.1 - 1.6e-21 76.7 0.0 2.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK71107.1 - 2.1e-06 27.3 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK71107.1 - 0.0041 16.7 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Sugar_tr PF00083.24 KIK71109.1 - 4.2e-45 154.4 26.2 2.3e-43 148.7 26.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK71109.1 - 4.1e-15 55.6 41.9 1e-07 31.2 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIK71109.1 - 1.2e-05 24.1 27.1 0.0007 18.3 6.2 3.3 2 2 1 3 3 3 3 MFS/sugar transport protein DUF5345 PF17280.2 KIK71109.1 - 0.063 13.3 0.3 0.063 13.3 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF5336 PF17270.2 KIK71109.1 - 0.14 11.8 4.7 0.095 12.3 1.5 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5336) SLS PF14611.6 KIK71110.1 - 5.6e-10 39.4 0.0 2.3e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.12 KIK71111.1 - 3.6e-80 268.6 23.7 3.6e-80 268.6 23.7 2.8 2 1 0 2 2 2 1 Spb1 C-terminal domain FtsJ PF01728.19 KIK71111.1 - 3.7e-58 196.5 0.1 2e-57 194.1 0.0 2.2 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KIK71111.1 - 1.3e-46 158.4 4.2 1.3e-46 158.4 4.2 5.7 4 3 1 5 5 5 1 Domain of unknown function (DUF3381) Lar_N PF09861.9 KIK71111.1 - 0.0062 15.7 0.2 0.0062 15.7 0.2 1.8 2 0 0 2 2 2 1 Lactate racemase N-terminal domain DUF423 PF04241.15 KIK71112.1 - 4.6e-22 78.0 0.7 4.6e-22 78.0 0.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Bax1-I PF01027.20 KIK71112.1 - 0.018 14.9 4.0 0.021 14.7 4.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Sugar_tr PF00083.24 KIK71113.1 - 2.5e-48 165.1 29.3 5.3e-46 157.4 29.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK71113.1 - 4e-20 72.1 42.1 1.2e-11 44.1 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIK71113.1 - 4.2e-06 25.6 29.1 5e-05 22.1 7.6 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein DUF5336 PF17270.2 KIK71113.1 - 0.0038 16.9 3.1 0.0068 16.1 1.0 2.4 2 1 0 2 2 2 1 Family of unknown function (DUF5336) eIF2A PF08662.11 KIK71114.1 - 9e-40 136.6 0.6 2.2e-36 125.6 0.1 4.2 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KIK71114.1 - 9.9e-05 22.1 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KIK71114.1 - 0.00088 20.0 1.6 1.5 9.8 0.1 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat CBM_2 PF00553.19 KIK71114.1 - 0.012 16.0 0.8 0.023 15.0 0.2 1.7 2 0 0 2 2 2 0 Cellulose binding domain Hap4_Hap_bind PF10297.9 KIK71115.1 - 5e-06 26.4 3.8 1.1e-05 25.4 3.8 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KIK71115.1 - 0.00068 19.7 15.4 0.0047 17.0 15.3 2.1 1 1 0 1 1 1 1 bZIP transcription factor HAUS-augmin3 PF14932.6 KIK71115.1 - 0.005 16.5 0.9 0.0071 15.9 0.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ZapB PF06005.12 KIK71115.1 - 0.54 10.7 7.2 1.2 9.6 7.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KIK71115.1 - 0.8 9.8 15.8 0.48 10.6 4.2 2.5 1 1 0 2 2 2 0 Basic region leucine zipper PPR_2 PF13041.6 KIK71116.1 - 2.6e-24 85.2 0.0 1.2e-07 31.8 0.0 6.6 4 3 4 8 8 8 5 PPR repeat family PPR_3 PF13812.6 KIK71116.1 - 4.3e-21 74.8 0.4 2.9e-08 33.7 0.0 5.8 5 2 2 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIK71116.1 - 2.4e-18 65.5 0.0 9.4e-06 25.2 0.0 5.6 6 0 0 6 6 6 3 PPR repeat PPR PF01535.20 KIK71116.1 - 4.1e-16 58.0 0.0 1.1e-05 25.4 0.0 5.8 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KIK71116.1 - 2.3e-10 40.2 0.1 3.7e-05 23.2 0.0 4.0 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIK71116.1 - 0.001 19.7 4.6 1.8 9.6 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat ECSIT PF06239.11 KIK71116.1 - 0.017 14.2 0.0 3.2 6.8 0.0 3.3 4 1 1 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway TraC PF07820.12 KIK71116.1 - 0.11 12.9 0.2 25 5.3 0.2 2.4 2 0 0 2 2 2 0 TraC-like protein TPR_19 PF14559.6 KIK71116.1 - 0.13 12.7 0.7 40 4.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 KIK71118.1 - 1.7e-24 86.3 0.0 9.2e-23 80.5 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_S28e PF01200.18 KIK71119.1 - 2.5e-29 101.1 0.2 3.3e-29 100.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.20 KIK71120.1 - 2.3e-17 63.4 0.0 3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KIK71120.1 - 0.0036 16.8 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 KIK71120.1 - 0.052 12.9 0.0 0.088 12.1 0.0 1.4 1 1 0 1 1 1 0 Mannosyltransferase putative Peptidase_M22 PF00814.25 KIK71121.1 - 1.9e-81 273.7 0.0 2.3e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KIK71121.1 - 0.006 16.3 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus 2-oxoacid_dh PF00198.23 KIK71122.1 - 1.3e-81 273.5 0.0 1.8e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK71122.1 - 4.4e-18 64.9 1.5 4.4e-18 64.9 1.5 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 KIK71122.1 - 6.4e-14 52.0 0.4 1.4e-13 50.9 0.4 1.6 1 0 0 1 1 1 1 e3 binding domain AAA_5 PF07728.14 KIK71124.1 - 7.4e-11 42.2 0.0 2.3e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK71124.1 - 1.5e-07 31.7 0.0 4.8e-07 30.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIK71124.1 - 0.00027 21.4 0.1 0.021 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KIK71124.1 - 0.00031 21.2 0.0 0.0011 19.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK71124.1 - 0.00044 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK71124.1 - 0.00061 19.2 0.0 0.077 12.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK71124.1 - 0.0021 18.4 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_PrkA PF08298.11 KIK71124.1 - 0.0028 16.6 0.0 0.0079 15.1 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_14 PF13173.6 KIK71124.1 - 0.0037 17.3 0.0 0.0097 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KIK71124.1 - 0.0063 15.9 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 KIK71124.1 - 0.042 14.0 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK71124.1 - 0.044 13.7 0.1 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 KIK71124.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIK71124.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIK71124.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KIK71124.1 - 0.16 12.1 0.0 0.54 10.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIK71124.1 - 0.16 11.4 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_32 PF13654.6 KIK71124.1 - 0.18 10.5 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SPOUT_MTase PF02590.17 KIK71124.1 - 0.22 11.5 0.1 9 6.3 0.0 2.5 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase SH3_9 PF14604.6 KIK71125.1 - 3.4e-08 33.2 0.0 6.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK71125.1 - 0.0033 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_16 PF18348.1 KIK71125.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain EXOSC1 PF10447.9 KIK71126.1 - 1.2e-18 67.7 2.0 1.4e-13 51.4 0.6 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KIK71126.1 - 0.0045 16.7 0.4 0.014 15.2 0.4 1.9 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region NUDE_C PF04880.13 KIK71127.1 - 6.4e-08 33.3 8.5 6.4e-08 33.3 8.5 5.8 1 1 3 4 4 2 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KIK71127.1 - 0.022 15.6 8.1 0.022 15.6 8.1 4.2 3 1 2 5 5 4 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KIK71127.1 - 0.25 11.9 31.9 3.3 8.2 14.9 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DegS PF05384.11 KIK71127.1 - 0.35 10.4 15.2 0.028 13.9 6.0 2.5 2 1 1 3 3 3 0 Sensor protein DegS TPR_MLP1_2 PF07926.12 KIK71127.1 - 0.48 10.5 31.4 0.15 12.2 5.9 3.7 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 KIK71127.1 - 0.49 9.3 18.7 6.1 5.7 18.8 2.2 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 HIP1_clath_bdg PF16515.5 KIK71127.1 - 0.72 10.5 22.4 6.5 7.4 2.0 3.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2353 PF09789.9 KIK71127.1 - 0.88 8.9 23.0 0.054 12.9 10.3 2.9 2 1 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF4472 PF14739.6 KIK71127.1 - 2.1 9.1 16.7 0.56 11.0 5.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) FapA PF03961.13 KIK71127.1 - 2.9 6.4 13.5 3.5 6.1 8.5 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A GAS PF13851.6 KIK71127.1 - 3.4 7.0 26.9 4 6.7 18.1 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KIK71127.1 - 3.7 7.8 25.9 8.9 6.6 0.2 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 KIK71127.1 - 3.7 4.9 20.3 6.1 4.2 20.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 KIK71127.1 - 5 6.1 20.3 7.5 5.5 9.6 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 KIK71127.1 - 6.6 7.1 18.3 0.24 11.7 5.2 3.9 2 1 2 4 4 4 0 Tup N-terminal Cys_Met_Meta_PP PF01053.20 KIK71129.1 - 6.5e-28 97.3 0.0 8.4e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Tcf25 PF04910.14 KIK71130.1 - 5.3e-96 321.7 0.0 8e-96 321.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SAGA-Tad1 PF12767.7 KIK71130.1 - 0.17 11.6 4.3 2.3 7.9 5.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4100 PF13352.6 KIK71130.1 - 2.7 7.7 8.9 5.9 6.6 8.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) EamA PF00892.20 KIK71131.1 - 1e-07 32.2 37.4 4.7e-06 26.8 6.9 3.1 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KIK71131.1 - 0.00015 21.1 18.9 0.0014 17.9 12.2 2.6 2 1 0 2 2 2 2 Purine nucleobase transmembrane transport DUF3955 PF13127.6 KIK71131.1 - 0.0017 18.1 0.4 0.0017 18.1 0.4 4.5 5 1 1 6 6 6 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 KIK71131.1 - 0.034 13.7 16.5 0.076 12.5 12.4 2.7 2 1 0 2 2 2 0 Solute carrier family 35 DPM2 PF07297.12 KIK71131.1 - 0.76 10.1 0.0 0.76 10.1 0.0 4.5 4 1 0 4 4 4 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pho86 PF11124.8 KIK71131.1 - 2.5 7.5 6.9 0.84 9.0 0.4 2.5 3 0 0 3 3 3 0 Inorganic phosphate transporter Pho86 BRCT_2 PF16589.5 KIK71132.1 - 6e-11 42.6 0.0 2.4e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIK71132.1 - 8e-09 35.6 3.2 2.5e-08 34.0 3.2 1.8 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KIK71132.1 - 1.2 9.7 5.9 0.94 10.1 2.2 2.5 2 1 1 3 3 3 0 Rap1, DNA-binding FAD-oxidase_C PF02913.19 KIK71133.1 - 3.7e-57 193.8 0.0 4.7e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK71133.1 - 2.7e-34 117.9 0.1 4.8e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAPDH_C PF16654.5 KIK71133.1 - 0.17 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain GYF PF02213.16 KIK71134.1 - 1.2e-15 56.9 0.1 2.5e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KIK71134.1 - 0.0056 16.5 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 GYF domain 2 ERCC4 PF02732.15 KIK71135.1 - 0.0064 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain DAG_kinase_N PF14513.6 KIK71135.1 - 0.0072 16.6 4.8 0.016 15.4 4.8 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus LAP1C PF05609.12 KIK71135.1 - 0.013 14.6 6.8 0.02 14.0 6.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2229 PF09989.9 KIK71135.1 - 0.13 11.9 1.6 0.24 11.0 1.6 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DBINO PF13892.6 KIK71135.1 - 0.17 12.2 16.7 0.4 11.0 16.7 1.6 1 0 0 1 1 1 0 DNA-binding domain RR_TM4-6 PF06459.12 KIK71135.1 - 1.3 8.7 12.7 2.1 8.1 12.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KIK71135.1 - 2 7.7 6.7 3.6 6.8 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KIK71135.1 - 4.3 6.0 8.2 5.7 5.6 8.2 1.3 1 0 0 1 1 1 0 Presenilin AMP-binding PF00501.28 KIK71136.1 - 1.3e-50 172.3 0.0 1.7e-43 148.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KIK71136.1 - 2.9e-18 66.6 0.0 7e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Alginate_lyase PF05426.12 KIK71137.1 - 6.6e-48 163.6 0.2 3.4e-46 158.0 0.0 2.2 2 0 0 2 2 2 2 Alginate lyase Herpes_LMP2 PF07415.11 KIK71137.1 - 0.41 9.4 3.2 0.57 8.9 3.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ras PF00071.22 KIK71138.1 - 7e-55 185.1 0.0 8.4e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK71138.1 - 1.7e-33 115.3 0.0 2.5e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK71138.1 - 3.4e-14 52.7 0.0 1.8e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK71138.1 - 5.4e-06 25.9 0.0 7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK71138.1 - 5.1e-05 22.9 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK71138.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK71138.1 - 0.00016 22.1 0.5 0.00029 21.3 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain MRI PF15325.6 KIK71138.1 - 0.2 12.8 2.3 0.39 11.8 2.3 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Arrestin_C PF02752.22 KIK71139.1 - 0.047 14.2 1.5 0.11 12.9 1.5 1.6 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain ARID PF01388.21 KIK71140.1 - 4.4e-12 46.5 0.0 9.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1764 PF08576.10 KIK71141.1 - 3.7e-09 37.4 9.7 4.7e-07 30.6 9.7 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Cyclin_C_2 PF16899.5 KIK71142.1 - 3.6e-18 65.9 0.8 1.7e-17 63.7 0.0 2.4 3 0 0 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KIK71142.1 - 1.4e-05 24.9 0.1 2.6e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sde2_N_Ubi PF13019.6 KIK71142.1 - 0.014 15.3 3.2 0.039 13.8 3.2 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain CO_dh PF02552.16 KIK71142.1 - 0.044 13.6 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AAA_18 PF13238.6 KIK71145.1 - 8.4e-32 110.4 0.0 1.3e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIK71145.1 - 1.1e-06 29.1 0.0 9.8e-06 26.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK71145.1 - 6.4e-05 23.1 0.0 0.0084 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK71145.1 - 0.00021 21.6 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KIK71145.1 - 0.00026 20.7 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 KIK71145.1 - 0.0003 20.7 0.2 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA PF00004.29 KIK71145.1 - 0.0004 20.8 0.0 0.0011 19.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIK71145.1 - 0.0036 17.6 0.1 0.009 16.3 0.0 1.8 2 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KIK71145.1 - 0.0037 17.2 0.4 0.13 12.1 0.1 2.2 2 0 0 2 2 2 1 NTPase ADK PF00406.22 KIK71145.1 - 0.0041 17.2 0.0 0.077 13.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase DUF218 PF02698.17 KIK71145.1 - 0.0041 17.1 0.2 0.011 15.7 0.2 1.7 2 0 0 2 2 2 1 DUF218 domain KTI12 PF08433.10 KIK71145.1 - 0.0074 15.8 0.1 0.032 13.7 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 KIK71145.1 - 0.028 13.6 0.2 0.049 12.9 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KIK71145.1 - 0.045 14.1 0.2 0.1 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KIK71145.1 - 0.046 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 KIK71145.1 - 0.049 13.8 0.3 0.22 11.6 0.3 1.9 1 1 0 1 1 1 0 Shikimate kinase MeaB PF03308.16 KIK71145.1 - 0.056 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 KIK71145.1 - 0.059 13.7 0.2 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KIK71145.1 - 0.08 13.1 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIK71145.1 - 0.085 13.4 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ATPase PF06745.13 KIK71145.1 - 0.095 12.0 0.7 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KIK71145.1 - 0.097 12.4 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIK71145.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIK71145.1 - 0.12 12.5 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK71145.1 - 0.12 11.6 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KIK71145.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 KIK71145.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KIK71145.1 - 0.14 11.9 0.1 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK71145.1 - 0.15 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sin_N PF04801.13 KIK71147.1 - 3.1e-21 76.1 0.1 3.9e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region LuxQ-periplasm PF09308.10 KIK71147.1 - 0.14 11.6 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic DnaJ PF00226.31 KIK71150.1 - 2.5e-17 62.7 2.9 4e-17 62.1 2.9 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KIK71150.1 - 0.0011 19.3 2.1 0.0016 18.7 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 KIK71150.1 - 0.44 10.3 3.7 0.85 9.4 3.7 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 KIK71150.1 - 1.4 9.1 5.4 2.8 8.1 5.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 KIK71150.1 - 6.6 6.8 8.6 30 4.7 8.6 2.1 1 1 0 1 1 1 0 Glycine zipper LIM PF00412.22 KIK71152.1 - 1.2e-12 47.9 29.5 1.4e-07 31.6 1.7 6.3 5 1 0 5 5 5 3 LIM domain Sgf11 PF08209.11 KIK71152.1 - 5.8 6.6 17.4 15 5.3 0.1 5.7 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) FMN_dh PF01070.18 KIK71153.1 - 1.9e-108 362.6 0.0 2.3e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK71153.1 - 7.9e-21 74.0 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIK71153.1 - 0.00056 19.1 0.4 0.0017 17.6 0.4 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIK71153.1 - 0.002 17.2 0.9 0.0085 15.1 0.1 2.1 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KIK71153.1 - 0.041 13.3 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase KASH_CCD PF14662.6 KIK71154.1 - 0.00021 21.2 6.6 0.00036 20.4 6.6 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Tmemb_cc2 PF10267.9 KIK71154.1 - 0.0054 15.9 7.6 0.0092 15.2 7.6 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Seryl_tRNA_N PF02403.22 KIK71154.1 - 0.012 15.9 4.7 0.012 15.9 4.7 1.9 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 KIK71154.1 - 0.015 15.3 5.8 0.04 14.0 5.8 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KIK71154.1 - 0.018 13.9 5.6 0.031 13.2 5.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Adaptin_binding PF10199.9 KIK71154.1 - 0.021 15.4 2.1 0.021 15.4 2.1 2.8 1 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 COG6 PF06419.11 KIK71154.1 - 0.027 12.7 5.4 0.041 12.1 5.4 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Macoilin PF09726.9 KIK71154.1 - 0.032 12.8 6.5 0.045 12.3 6.5 1.2 1 0 0 1 1 1 0 Macoilin family Rx_N PF18052.1 KIK71154.1 - 0.074 13.3 1.6 0.19 12.0 1.6 1.6 1 0 0 1 1 1 0 Rx N-terminal domain Phage_GP20 PF06810.11 KIK71154.1 - 0.077 12.8 7.5 0.31 10.9 5.8 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 GAS PF13851.6 KIK71154.1 - 0.082 12.3 5.3 0.16 11.3 5.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PCRF PF03462.18 KIK71154.1 - 0.11 12.3 3.0 0.21 11.4 3.0 1.4 1 0 0 1 1 1 0 PCRF domain Allexi_40kDa PF05549.11 KIK71154.1 - 0.13 11.7 2.1 0.25 10.8 2.1 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein FapA PF03961.13 KIK71154.1 - 0.15 10.6 1.2 0.22 10.1 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tup_N PF08581.10 KIK71154.1 - 0.2 12.0 5.8 0.39 11.0 5.8 1.5 1 0 0 1 1 1 0 Tup N-terminal COG5 PF10392.9 KIK71154.1 - 0.22 11.7 5.4 0.37 11.0 4.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DHR10 PF18595.1 KIK71154.1 - 0.27 11.3 8.4 0.54 10.3 8.4 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KIK71154.1 - 0.32 11.5 8.2 0.47 11.0 2.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KIK71154.1 - 0.41 11.0 7.5 3.2 8.1 1.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 KIK71154.1 - 0.51 11.1 3.2 3.3 8.5 3.8 1.9 1 1 1 2 2 2 0 Occludin homology domain DASH_Dam1 PF08653.10 KIK71154.1 - 0.52 10.1 4.5 2.3 8.1 0.4 2.3 1 1 0 2 2 2 0 DASH complex subunit Dam1 TMPIT PF07851.13 KIK71154.1 - 0.71 9.1 3.4 1 8.5 3.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KIK71154.1 - 0.71 7.7 2.4 0.41 8.5 0.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 KIK71154.1 - 0.83 9.8 4.1 1.8 8.7 4.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family KELK PF15796.5 KIK71154.1 - 0.9 10.0 6.8 1.4 9.4 3.9 2.3 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2203 PF09969.9 KIK71154.1 - 1.2 9.8 3.2 4.9 7.9 3.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Laminin_II PF06009.12 KIK71154.1 - 1.3 9.1 7.4 2.9 7.9 7.4 1.5 1 0 0 1 1 1 0 Laminin Domain II Prominin PF05478.11 KIK71154.1 - 1.5 6.7 3.8 2 6.2 3.8 1.1 1 0 0 1 1 1 0 Prominin DUF745 PF05335.13 KIK71154.1 - 1.6 8.4 4.9 2.9 7.6 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 KIK71154.1 - 1.6 8.8 6.2 5.9 6.9 6.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 KIK71154.1 - 1.7 8.2 5.7 4.5 6.8 5.6 1.7 1 1 0 1 1 1 0 fzo-like conserved region Cep57_CLD_2 PF14197.6 KIK71154.1 - 2.1 8.5 11.3 1 9.5 3.3 2.9 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 NPR3 PF03666.13 KIK71154.1 - 3 6.6 12.0 0.044 12.6 4.6 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 FliD_N PF02465.18 KIK71154.1 - 3.2 8.5 11.9 0.96 10.2 1.2 2.7 2 1 1 3 3 2 0 Flagellar hook-associated protein 2 N-terminus Fmp27_WPPW PF10359.9 KIK71154.1 - 3.7 6.3 8.5 0.69 8.7 4.3 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain G-gamma PF00631.22 KIK71154.1 - 4.1 7.5 5.8 1.6 8.8 0.2 2.8 2 1 1 3 3 3 0 GGL domain DUF5094 PF17015.5 KIK71154.1 - 5.3 7.1 6.6 3.7 7.6 4.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) DKCLD PF08068.12 KIK71155.1 - 5.3e-33 112.9 0.2 3.2e-32 110.4 0.3 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KIK71155.1 - 1.7e-23 83.7 0.3 1.2e-19 71.1 0.3 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KIK71155.1 - 1.1e-22 80.0 1.4 2.1e-22 79.0 1.4 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KIK71155.1 - 1.4e-21 76.2 1.4 3.4e-21 75.0 1.4 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KIK71155.1 - 0.015 15.5 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain GAGA_bind PF06217.12 KIK71155.1 - 0.92 9.7 8.3 1.5 9.1 8.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KIK71155.1 - 3.8 7.3 19.4 5.5 6.7 19.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 KIK71155.1 - 8.2 6.9 9.4 13 6.3 9.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_L22e PF01776.17 KIK71156.1 - 4.7e-45 152.4 1.8 5.4e-45 152.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2660 PF10859.8 KIK71156.1 - 0.034 14.6 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) AdoMet_Synthase PF01941.19 KIK71156.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) HA2 PF04408.23 KIK71157.1 - 1e-17 64.4 0.0 3.4e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK71157.1 - 1.8e-14 54.0 0.0 5.7e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIK71157.1 - 2.6e-08 34.1 0.0 6.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KIK71157.1 - 3.2e-07 30.7 0.1 9.4e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KIK71157.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KIK71157.1 - 0.0054 17.3 0.1 0.048 14.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter T2SSE PF00437.20 KIK71157.1 - 0.033 13.3 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KIK71157.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 KIK71157.1 - 0.069 13.1 0.2 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 KIK71157.1 - 0.071 12.4 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC SNF2_N PF00176.23 KIK71158.1 - 6.2e-66 222.5 0.5 1e-65 221.8 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KIK71158.1 - 1.6e-47 161.2 17.6 1.6e-47 161.2 17.6 2.5 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 KIK71158.1 - 3.8e-15 56.2 0.0 1e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK71158.1 - 3.9e-06 27.0 0.0 9.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK71158.1 - 0.00017 20.9 0.0 0.0014 17.9 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.20 KIK71159.1 - 1.8e-121 405.3 0.0 2.4e-121 404.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KIK71159.1 - 2.1e-20 72.9 0.1 5.4e-20 71.5 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus PEX11 PF05648.14 KIK71160.1 - 5.3e-51 173.2 1.9 5.9e-51 173.1 1.9 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TPR_4 PF07721.14 KIK71160.1 - 0.083 13.6 0.3 2 9.3 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Cmc1 PF08583.10 KIK71161.1 - 1.5e-10 40.9 1.2 1.8e-10 40.7 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KIK71161.1 - 0.022 15.1 2.1 0.22 11.9 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KIK71161.1 - 0.051 13.7 2.3 2.6 8.3 0.2 2.2 2 0 0 2 2 2 0 CHCH domain CobT_C PF11775.8 KIK71161.1 - 0.057 13.1 0.0 0.061 13.0 0.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain LIAS_N PF16881.5 KIK71162.1 - 8.4e-26 90.5 0.0 2.4e-25 89.1 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KIK71162.1 - 9.6e-15 55.3 0.0 1.7e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Rad51 PF08423.11 KIK71163.1 - 0.00044 19.6 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 Rad51 HAP1_N PF04849.13 KIK71164.1 - 0.027 13.7 23.0 1.5 7.9 12.6 3.4 3 0 0 3 3 3 0 HAP1 N-terminal conserved region Aminopep PF10023.9 KIK71164.1 - 0.17 11.2 7.8 0.28 10.5 7.8 1.3 1 0 0 1 1 1 0 Putative aminopeptidase WD40_alt PF14077.6 KIK71164.1 - 0.37 10.7 1.5 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif HAUS-augmin3 PF14932.6 KIK71164.1 - 3.4 7.2 31.3 1.3 8.5 12.6 3.0 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 TSC22 PF01166.18 KIK71164.1 - 4.7 7.6 6.3 7.9 6.9 0.5 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family SLX9 PF15341.6 KIK71165.1 - 7.2e-22 78.2 5.9 7.2e-22 78.2 5.9 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF917 PF06032.12 KIK71166.1 - 2.1e-121 405.1 1.1 7.5e-121 403.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KIK71166.1 - 7.7e-30 104.1 3.6 1.1e-28 100.3 1.6 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIK71166.1 - 3.7e-28 98.4 0.0 2e-25 89.5 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ROK PF00480.20 KIK71166.1 - 0.00082 18.9 0.0 0.0026 17.3 0.0 1.9 1 0 0 1 1 1 1 ROK family MutL PF13941.6 KIK71166.1 - 0.0012 17.5 0.7 0.1 11.2 0.1 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 KIK71166.1 - 0.0035 16.9 0.0 0.0035 16.9 0.0 2.8 3 2 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KIK71166.1 - 0.0092 15.2 0.1 3 7.0 0.0 2.4 2 0 0 2 2 2 2 StbA protein Es2 PF09751.9 KIK71167.1 - 1.6e-90 304.9 9.6 2e-90 304.6 9.6 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.9 KIK71168.1 - 1.6e-31 108.7 11.0 1.9e-31 108.6 11.0 1.0 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pkinase PF00069.25 KIK71170.1 - 1.9e-66 224.2 0.0 2.2e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71170.1 - 5.6e-26 91.4 0.0 7.1e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK71170.1 - 4.4e-06 26.2 0.2 0.0032 16.8 0.1 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KIK71170.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIK71170.1 - 0.039 12.9 0.1 0.073 12.0 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK71170.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIK71170.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 KIK71171.1 - 9.1e-34 117.7 0.1 1.5e-33 117.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK71171.1 - 0.001 19.5 0.4 0.0019 18.6 0.4 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KIK71171.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TGT PF01702.18 KIK71172.1 - 3.7e-31 108.5 0.0 7.3e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase GFO_IDH_MocA PF01408.22 KIK71173.1 - 4.1e-19 69.6 0.1 5.9e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KIK71173.1 - 0.11 13.1 0.1 0.18 12.5 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TTL PF03133.15 KIK71175.1 - 1.3e-50 172.3 0.0 1.8e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 KIK71175.1 - 0.092 12.8 0.0 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp domain MMM1 PF10296.9 KIK71176.1 - 2.3e-40 138.7 1.5 4.4e-22 78.6 0.0 3.0 1 1 2 3 3 3 3 Maintenance of mitochondrial morphology protein 1 MRP-L20 PF12824.7 KIK71177.1 - 0.0029 17.8 0.1 0.013 15.7 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 RNA_pol_Rpb8 PF03870.15 KIK71178.1 - 2.1e-41 141.4 1.4 1.5e-27 96.5 0.1 2.0 2 0 0 2 2 2 2 RNA polymerase Rpb8 Sec7 PF01369.20 KIK71180.1 - 1.2e-33 116.3 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KIK71180.1 - 8.9e-12 45.4 0.0 1.8e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK71180.1 - 1e-06 29.2 0.0 2.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.11 KIK71181.1 - 2.2e-123 411.2 0.0 2.2e-123 411.2 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KIK71181.1 - 1.6e-07 31.6 0.0 3.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK71181.1 - 0.00069 20.0 0.1 0.0022 18.3 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK71181.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain FAM76 PF16046.5 KIK71181.1 - 2.5 7.4 12.2 4.2 6.6 12.2 1.3 1 0 0 1 1 1 0 FAM76 protein LSM PF01423.22 KIK71182.1 - 3.8e-17 61.7 0.1 5.3e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK71182.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Hfq protein DUF4061 PF13270.6 KIK71183.1 - 1.2 9.5 5.9 1.6 9.1 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) WAC_Acf1_DNA_bd PF10537.9 KIK71184.1 - 1.7e-35 121.6 0.5 1.7e-35 121.6 0.5 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KIK71184.1 - 4.2e-32 110.6 0.0 4.2e-32 110.6 0.0 3.0 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KIK71184.1 - 3.8e-14 52.7 0.9 1e-13 51.4 0.9 1.7 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KIK71184.1 - 7.6e-06 25.3 0.0 1.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CENP-H PF05837.12 KIK71184.1 - 0.006 17.0 0.8 0.006 17.0 0.8 3.9 3 1 1 4 4 4 1 Centromere protein H (CENP-H) DUF5097 PF17020.5 KIK71184.1 - 0.099 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) DDHD PF02862.17 KIK71184.1 - 0.48 10.5 6.4 3.6 7.7 0.1 2.3 2 0 0 2 2 2 0 DDHD domain DUF3287 PF11690.8 KIK71184.1 - 1.6 8.4 6.2 0.65 9.7 1.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) DUF4407 PF14362.6 KIK71184.1 - 3.1 7.1 15.0 0.47 9.8 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 KIK71184.1 - 4.7 6.5 44.1 1.2 8.5 16.3 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PMT PF02366.18 KIK71186.1 - 2.2e-81 273.1 17.7 3.3e-81 272.5 17.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIK71186.1 - 9.7e-54 182.0 3.5 3.1e-53 180.4 3.5 1.9 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIK71186.1 - 3.1e-23 82.6 0.1 5.2e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIK71186.1 - 0.0088 16.3 12.8 0.023 14.9 12.8 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Metal_resist PF13801.6 KIK71186.1 - 0.08 13.1 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Heavy-metal resistance DUF4969 PF16339.5 KIK71186.1 - 0.26 11.7 0.7 0.71 10.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) GFO_IDH_MocA PF01408.22 KIK71188.1 - 7.9e-12 46.1 0.0 2.4e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK71188.1 - 0.021 14.8 0.1 0.081 12.9 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.6 KIK71188.1 - 0.023 15.2 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Sacchrp_dh_NADP PF03435.18 KIK71188.1 - 0.031 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cyclin_N PF00134.23 KIK71189.1 - 7.1e-38 129.2 0.9 1.5e-37 128.2 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK71189.1 - 1.4e-08 34.8 0.3 3.9e-08 33.4 0.3 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF4364 PF14277.6 KIK71189.1 - 0.085 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Complex1_LYR PF05347.15 KIK71191.1 - 1.5e-19 69.8 0.6 1.7e-19 69.6 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KIK71191.1 - 0.0023 18.5 0.2 0.0032 18.0 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 KIK71191.1 - 0.021 15.6 0.1 0.028 15.2 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Aa_trans PF01490.18 KIK71192.1 - 1.3e-55 188.8 26.0 1.5e-55 188.6 26.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIK71192.1 - 7.2e-05 22.0 14.7 7.2e-05 22.0 14.7 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Ehrlichia_rpt PF09528.10 KIK71192.1 - 0.26 10.8 2.0 0.48 9.9 2.0 1.4 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) DUF92 PF01940.16 KIK71196.1 - 1.7e-73 246.9 8.8 2e-73 246.7 8.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 CSN8_PSD8_EIF3K PF10075.9 KIK71197.1 - 4.5e-22 78.6 0.0 7.5e-22 77.9 0.0 1.4 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family WD40 PF00400.32 KIK71198.1 - 3e-53 176.6 17.4 1.4e-12 47.8 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71198.1 - 9.9e-20 70.6 0.5 0.00018 21.7 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK71198.1 - 7.9e-13 48.7 0.0 2.9e-05 24.0 0.0 3.1 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK71198.1 - 3.4e-08 33.2 0.0 2.8e-06 26.9 0.0 2.9 1 1 1 2 2 2 1 WD40-like domain Nup160 PF11715.8 KIK71198.1 - 1.1e-07 30.9 8.1 0.044 12.4 0.2 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK71198.1 - 7.8e-06 25.1 2.6 0.15 11.0 2.6 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KIK71198.1 - 0.0001 21.5 0.1 0.033 13.2 0.2 2.3 2 1 0 2 2 2 2 Coatomer WD associated region PALB2_WD40 PF16756.5 KIK71198.1 - 0.00012 21.1 1.3 0.86 8.5 0.0 3.8 1 1 4 5 5 5 3 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KIK71198.1 - 0.00055 18.8 1.2 2.2 6.9 0.0 3.1 1 1 2 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 KIK71198.1 - 0.0036 15.7 0.1 3.3 5.9 0.1 2.9 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 KIK71198.1 - 0.02 12.9 0.1 0.31 9.0 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Nbas_N PF15492.6 KIK71198.1 - 0.029 13.7 0.4 3.3 7.0 0.1 2.7 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KIK71198.1 - 0.033 13.3 0.1 0.3 10.1 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KIK71198.1 - 0.039 12.5 0.2 0.83 8.1 0.0 2.6 1 1 0 2 2 2 0 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 KIK71198.1 - 0.039 12.8 0.0 0.39 9.5 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Utp8 PF10395.9 KIK71198.1 - 0.065 11.7 0.0 0.56 8.7 0.0 1.9 1 1 0 1 1 1 0 Utp8 family Kelch_6 PF13964.6 KIK71198.1 - 0.18 12.1 0.7 0.99 9.8 0.1 2.5 3 0 0 3 3 2 0 Kelch motif ubiquitin PF00240.23 KIK71199.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KIK71199.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK71199.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK71199.1 - 1.6e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK71199.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK71199.1 - 1.7e-17 63.5 11.5 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 KIK71199.1 - 5.3e-16 59.1 2.2 0.55 10.8 0.0 5.2 1 1 0 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIK71199.1 - 3.1e-12 46.6 0.7 1.6 8.5 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KIK71199.1 - 3.7e-09 36.3 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KIK71199.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 KIK71199.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 KIK71199.1 - 1.9e-07 31.4 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 KIK71199.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 KIK71199.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KIK71199.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 KIK71199.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIK71199.1 - 2.3e-05 23.9 0.1 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIK71199.1 - 6e-05 23.6 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 KIK71199.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIK71199.1 - 0.0007 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIK71199.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIK71199.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIK71199.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIK71199.1 - 0.46 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIK71199.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIK71199.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIK71199.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 KIK71199.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e Fcf1 PF04900.12 KIK71200.1 - 4.1e-32 110.5 0.3 7.3e-32 109.7 0.3 1.4 1 0 0 1 1 1 1 Fcf1 DUF2012 PF09430.10 KIK71201.1 - 7.7e-22 77.7 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 KIK71201.1 - 0.007 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II FAM180 PF15173.6 KIK71201.1 - 0.081 12.9 0.0 0.6 10.1 0.0 1.9 2 0 0 2 2 2 0 FAM180 family CarboxypepD_reg PF13620.6 KIK71201.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KIK71201.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 CarboxypepD_reg-like domain CAP PF00188.26 KIK71203.1 - 8.1e-24 84.9 2.0 2.3e-23 83.4 2.0 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SPATIAL PF15256.6 KIK71203.1 - 6.9 6.9 8.8 11 6.3 8.8 1.3 1 0 0 1 1 1 0 SPATIAL Cyclin_N PF00134.23 KIK71204.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK71204.1 - 8.7e-06 26.2 0.0 1.2e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin GST_N_3 PF13417.6 KIK71206.1 - 1.4e-06 28.6 0.0 6.5e-06 26.5 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK71206.1 - 0.018 15.4 0.0 0.055 13.8 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK71206.1 - 0.031 14.6 0.0 0.21 11.9 0.0 2.3 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain DUF1877 PF08974.10 KIK71206.1 - 0.21 11.7 0.3 0.38 10.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) DUF846 PF05832.12 KIK71208.1 - 1.7e-51 173.9 6.2 2.1e-51 173.6 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DSPc PF00782.20 KIK71209.1 - 4e-19 68.7 0.0 2.5e-17 62.9 0.0 2.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Nop14 PF04147.12 KIK71209.1 - 0.012 13.8 2.1 0.018 13.3 2.1 1.1 1 0 0 1 1 1 0 Nop14-like family RAP1 PF07218.11 KIK71209.1 - 5.6 5.1 4.6 10 4.3 4.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAD_binding_6 PF00970.24 KIK71210.1 - 4.3e-31 107.2 0.0 6.6e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIK71210.1 - 2.4e-29 102.2 0.0 3.9e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KIK71210.1 - 0.00013 22.1 0.1 0.0027 17.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Abhydrolase_6 PF12697.7 KIK71211.1 - 1.4e-10 42.2 1.3 1.4e-10 42.2 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK71211.1 - 4.2e-05 22.9 0.0 0.00013 21.4 0.0 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK71211.1 - 0.00028 20.6 0.0 0.00061 19.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK71211.1 - 0.2 11.1 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ndr PF03096.14 KIK71211.1 - 0.2 10.3 0.0 0.58 8.8 0.0 1.7 2 0 0 2 2 2 0 Ndr family LRR_4 PF12799.7 KIK71212.1 - 1.7e-11 44.1 13.9 0.042 14.3 0.2 7.0 7 1 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK71212.1 - 0.018 15.1 11.3 48 4.4 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_8 PF13855.6 KIK71212.1 - 0.023 14.5 11.7 4.2 7.2 0.9 6.1 5 2 0 5 5 5 0 Leucine rich repeat BESS PF02944.20 KIK71212.1 - 0.06 13.2 0.2 0.69 9.8 0.4 2.6 2 0 0 2 2 2 0 BESS motif SSP160 PF06933.11 KIK71213.1 - 0.39 8.9 17.2 0.41 8.8 17.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BES1_N PF05687.13 KIK71213.1 - 5.1 7.5 10.1 6.4 7.1 10.1 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Sortilin-Vps10 PF15902.5 KIK71214.1 - 6.1e-13 48.4 6.3 0.00038 19.4 0.1 5.3 5 0 0 5 5 5 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 KIK71214.1 - 0.0025 17.6 22.6 2.7 8.4 0.1 8.7 8 0 0 8 8 8 4 BNR/Asp-box repeat BNR_6 PF15899.5 KIK71214.1 - 0.1 12.7 1.3 80 3.7 0.0 4.9 4 0 0 4 4 4 0 BNR-Asp box repeat zf-tcix PF14952.6 KIK71215.1 - 0.037 13.6 0.4 0.078 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding SMN PF06003.12 KIK71215.1 - 0.5 9.6 3.6 0.59 9.4 0.1 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Kdo PF06293.14 KIK71216.1 - 0.036 13.4 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIK71216.1 - 0.049 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain AA_permease PF00324.21 KIK71217.1 - 1.1e-129 433.2 33.2 1.3e-129 433.0 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK71217.1 - 2.5e-36 125.4 39.3 3.6e-36 124.9 39.3 1.2 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.20 KIK71218.1 - 3.5e-41 141.4 0.0 5.1e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 KIK71218.1 - 7.3e-09 35.3 0.5 0.00068 19.4 0.6 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIK71218.1 - 2.3e-05 24.6 0.4 0.0027 18.1 0.2 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) PAXNEB PF05625.11 KIK71219.1 - 1.9e-56 191.8 0.0 3.1e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 PAXNEB protein Peptidase_S24 PF00717.23 KIK71220.1 - 3.5e-08 33.3 0.0 5.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIK71220.1 - 7.9e-06 25.7 0.0 0.0045 16.8 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_1 PF00515.28 KIK71221.1 - 3.9e-05 23.3 1.0 0.0002 21.0 0.3 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK71221.1 - 0.0012 18.8 5.5 0.0015 18.4 0.4 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK71221.1 - 0.035 14.6 0.9 0.035 14.6 0.9 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK71221.1 - 0.035 14.1 0.3 0.14 12.2 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK71221.1 - 0.036 14.3 0.1 0.16 12.3 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4795 PF16043.5 KIK71221.1 - 0.037 13.6 0.9 0.049 13.2 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ParD PF09386.10 KIK71221.1 - 0.053 13.9 1.2 1.6 9.2 0.3 2.3 2 0 0 2 2 2 0 Antitoxin ParD TMF_TATA_bd PF12325.8 KIK71221.1 - 0.099 12.9 2.7 0.25 11.6 2.0 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_14 PF13428.6 KIK71221.1 - 0.1 13.5 0.2 0.51 11.3 0.2 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat SnoaL_2 PF12680.7 KIK71222.1 - 0.00013 22.5 0.1 0.00016 22.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4361 PF14274.6 KIK71222.1 - 0.049 13.9 0.0 0.068 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) AlaDh_PNT_N PF05222.15 KIK71223.1 - 2.7e-28 99.0 0.0 3.9e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIK71223.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-Tim10_DDP PF02953.15 KIK71226.1 - 1.1e-22 79.4 2.4 1.4e-22 79.1 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.21 KIK71227.1 - 9.1e-19 67.4 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KIK71227.1 - 1.2e-07 31.7 0.2 2.1e-06 27.7 0.3 2.3 2 0 0 2 2 2 1 Acyltransferase C-terminus Aa_trans PF01490.18 KIK71228.1 - 6.5e-27 94.3 37.1 8.7e-27 93.9 37.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CoxIIa PF08113.11 KIK71228.1 - 0.011 15.6 2.0 0.011 15.6 2.0 3.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family PPPI_inhib PF14895.6 KIK71228.1 - 0.04 13.1 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor DUF3341 PF11821.8 KIK71228.1 - 2.3 7.8 13.4 0.07 12.8 4.6 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3341) F-box-like PF12937.7 KIK71229.1 - 0.0061 16.4 2.7 0.015 15.2 2.7 1.7 1 0 0 1 1 1 1 F-box-like Ribosomal_L28e PF01778.17 KIK71230.1 - 9.4e-27 94.0 0.1 1.2e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Hydrolase_4 PF12146.8 KIK71231.1 - 4.9e-06 26.0 0.1 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK71231.1 - 4.1e-05 24.3 0.8 0.00042 21.0 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK71231.1 - 0.00013 21.7 0.7 0.00037 20.2 0.0 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold CSN4_RPN5_eIF3a PF18420.1 KIK71231.1 - 0.13 12.4 0.9 0.26 11.5 0.9 1.4 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain CD24 PF14984.6 KIK71231.1 - 0.46 10.8 7.6 2.9 8.2 7.6 2.4 1 1 0 1 1 1 0 CD24 protein RIFIN PF02009.16 KIK71232.1 - 0.1 12.5 1.5 0.13 12.1 1.5 1.1 1 0 0 1 1 1 0 Rifin DUF4366 PF14283.6 KIK71232.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2207 PF09972.9 KIK71232.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MGC-24 PF05283.11 KIK71232.1 - 0.15 12.5 11.8 0.41 11.1 11.8 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Orf78 PF06024.12 KIK71232.1 - 0.15 12.3 0.1 0.29 11.5 0.1 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Peptidase_M56 PF05569.11 KIK71232.1 - 0.22 10.7 1.2 0.31 10.2 1.2 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 AI-2E_transport PF01594.16 KIK71232.1 - 0.25 10.5 3.4 0.52 9.4 3.4 1.5 1 1 0 1 1 1 0 AI-2E family transporter Stevor PF17410.2 KIK71232.1 - 0.26 10.8 1.2 0.36 10.3 1.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Plasmodium_Vir PF05795.11 KIK71232.1 - 0.84 9.0 3.7 1.1 8.7 3.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.6 KIK71232.1 - 2.8 7.9 16.8 11 6.0 15.3 2.4 1 1 1 2 2 2 0 TMEM154 protein family Septin PF00735.18 KIK71235.1 - 1e-109 366.2 0.2 1.6e-109 365.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIK71235.1 - 2.3e-07 30.9 0.0 6.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK71235.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KIK71235.1 - 0.0042 16.7 0.1 0.17 11.4 0.0 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK71235.1 - 0.0067 16.5 4.3 0.8 9.7 0.1 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KIK71235.1 - 0.012 15.6 4.2 0.032 14.1 0.6 3.0 3 1 0 3 3 3 0 RsgA GTPase IIGP PF05049.13 KIK71235.1 - 0.019 14.0 0.1 0.048 12.7 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KIK71235.1 - 0.037 13.4 0.2 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KIK71235.1 - 0.094 13.2 2.6 2.8 8.4 2.4 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK71235.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK71235.1 - 0.14 12.4 0.5 1.1 9.5 0.0 2.5 3 1 0 3 3 3 0 AAA domain McyA_C PF12593.8 KIK71236.1 - 0.0043 16.8 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 Microcystin synthetase C terminal MutS_V PF00488.21 KIK71237.1 - 1.6e-70 237.0 0.0 3e-70 236.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK71237.1 - 7.8e-36 124.1 1.1 1.5e-35 123.2 1.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIK71237.1 - 1.7e-21 76.5 0.0 4.1e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIK71237.1 - 2.9e-09 37.3 0.0 8e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KIK71237.1 - 0.00014 21.5 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK71237.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK71237.1 - 0.025 15.1 0.0 0.025 15.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain APH PF01636.23 KIK71238.1 - 5.3e-40 137.9 0.0 6.6e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK71238.1 - 0.00011 21.8 0.0 0.0009 18.9 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIK71238.1 - 0.05 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_3 PF07859.13 KIK71239.1 - 2.7e-40 138.5 0.0 6.3e-33 114.4 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK71239.1 - 6e-10 38.5 0.0 9.2e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK71239.1 - 0.044 12.6 0.1 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 KIK71239.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aconitase PF00330.20 KIK71240.1 - 5.1e-153 510.4 0.0 7e-153 509.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK71240.1 - 7.1e-34 117.0 0.0 1.2e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_4 PF01063.19 KIK71241.1 - 5.5e-31 108.2 0.0 7.9e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Gemini_AL2 PF01440.16 KIK71242.1 - 0.057 13.9 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Geminivirus AL2 protein SQS_PSY PF00494.19 KIK71243.1 - 1.6e-36 126.1 0.0 2e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase TM231 PF10149.9 KIK71244.1 - 0.36 10.1 1.5 0.36 10.1 0.3 1.5 2 0 0 2 2 2 0 Transmembrane protein 231 Miga PF10265.9 KIK71244.1 - 9.9 5.0 5.5 1.3 7.9 0.5 1.7 1 1 0 2 2 2 0 Mitoguardin Asn_synthase PF00733.21 KIK71245.1 - 2.9e-19 69.9 0.3 1.4e-09 38.1 0.6 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KIK71245.1 - 1.7e-08 34.4 0.0 4.7e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIK71245.1 - 0.0061 16.8 0.0 0.021 15.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 KIK71245.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.25 KIK71246.1 - 2.2e-22 79.9 6.3 6.5e-22 78.4 5.6 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 KIK71246.1 - 0.095 12.8 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain RRM_1 PF00076.22 KIK71247.1 - 3.4e-55 183.8 0.0 2e-19 69.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK71247.1 - 2.3e-08 33.7 0.0 0.00012 21.7 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK71247.1 - 1.4e-06 28.0 0.0 0.00028 20.7 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KIK71247.1 - 0.0033 17.5 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KIK71247.1 - 0.0068 16.5 0.0 0.16 12.1 0.0 2.9 3 1 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK71247.1 - 0.025 14.6 0.1 18 5.5 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif ATG16 PF08614.11 KIK71249.1 - 7.5e-52 176.5 18.5 9.2e-52 176.2 18.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CEP19 PF14933.6 KIK71249.1 - 0.0055 17.0 0.9 0.0055 17.0 0.9 1.8 1 1 1 2 2 2 1 CEP19-like protein KASH_CCD PF14662.6 KIK71249.1 - 0.024 14.5 21.2 0.053 13.3 3.0 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 KIK71249.1 - 0.029 14.6 23.2 0.044 14.0 9.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2288 PF10052.9 KIK71249.1 - 0.084 13.0 0.8 0.25 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) Fez1 PF06818.15 KIK71249.1 - 0.11 12.9 15.5 0.13 12.7 9.4 2.2 1 1 1 2 2 2 0 Fez1 DUF1054 PF06335.12 KIK71249.1 - 0.14 12.1 4.3 0.034 14.1 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) YabA PF06156.13 KIK71249.1 - 0.21 12.3 13.4 0.085 13.5 3.8 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 KIK71249.1 - 0.3 9.9 18.7 0.063 12.1 14.6 1.9 2 1 0 2 2 2 0 Spc7 kinetochore protein Phage_int_SAM_2 PF12834.7 KIK71249.1 - 0.52 11.0 6.0 1.3 9.8 0.1 2.6 3 0 0 3 3 2 0 Phage integrase, N-terminal EzrA PF06160.12 KIK71249.1 - 0.64 8.1 17.7 0.08 11.1 13.8 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 KIK71249.1 - 0.91 8.8 8.3 1.5 8.1 8.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KIK71249.1 - 1.2 9.6 20.5 3.2 8.2 1.8 3.7 1 1 2 3 3 3 0 Cell division protein ZapB Fib_alpha PF08702.10 KIK71249.1 - 1.3 9.2 11.9 0.72 10.0 7.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIK71249.1 - 1.8 8.7 8.4 7.5 6.6 6.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 KIK71249.1 - 2 7.6 9.7 5.5 6.2 8.1 1.9 1 1 1 2 2 2 0 Monopolar spindle protein 2 FAM76 PF16046.5 KIK71249.1 - 4.5 6.6 12.6 11 5.2 12.5 1.9 1 1 0 1 1 1 0 FAM76 protein FlxA PF14282.6 KIK71249.1 - 5.6 7.0 12.5 0.9 9.6 0.2 3.1 2 1 0 3 3 3 0 FlxA-like protein DUF4200 PF13863.6 KIK71249.1 - 5.7 7.4 20.6 0.097 13.1 9.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FUSC PF04632.12 KIK71249.1 - 5.8 5.3 8.2 6.3 5.2 7.6 1.2 1 1 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 KIK71249.1 - 7.5 7.1 17.6 19 5.8 2.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Ras PF00071.22 KIK71250.1 - 1.1e-57 194.2 0.2 1.3e-57 194.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK71250.1 - 2.2e-32 111.8 0.0 3.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK71250.1 - 7.3e-14 51.6 0.0 9.2e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK71250.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK71250.1 - 4.1e-07 29.6 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK71250.1 - 3.8e-06 26.6 0.0 0.00016 21.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK71250.1 - 4.4e-05 23.4 0.2 0.0044 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KIK71250.1 - 0.00038 20.3 0.4 0.018 14.8 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KIK71250.1 - 0.00062 19.5 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KIK71250.1 - 0.0012 18.2 0.3 0.046 13.0 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.19 KIK71250.1 - 0.0016 18.1 0.0 0.0053 16.4 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KIK71250.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIK71250.1 - 0.007 16.6 0.0 0.017 15.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK71250.1 - 0.0096 16.3 0.1 0.015 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIK71250.1 - 0.013 15.5 0.1 0.043 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIK71250.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK71250.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIK71250.1 - 0.025 15.1 0.0 0.93 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK71250.1 - 0.051 13.5 0.7 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KIK71250.1 - 0.052 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase Glyco_hydro_75 PF07335.11 KIK71250.1 - 0.066 13.5 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 KIK71250.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KIK71250.1 - 0.13 12.8 0.0 0.49 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Glucosamine_iso PF01182.20 KIK71251.1 - 1.6e-72 244.0 0.0 1.8e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase VIT PF08487.10 KIK71252.1 - 4.4e-25 88.0 0.0 9.6e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK71252.1 - 2.4e-20 73.0 0.1 7.2e-20 71.5 0.1 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK71252.1 - 8.6e-14 52.2 0.0 2.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK71252.1 - 1.3e-09 38.6 0.0 3.7e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIK71252.1 - 0.0023 17.4 0.3 0.0041 16.5 0.3 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KIK71252.1 - 0.029 14.3 0.2 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Pkinase PF00069.25 KIK71253.1 - 1.6e-64 217.8 0.0 1.8e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71253.1 - 2.7e-38 131.7 0.0 3.2e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK71253.1 - 0.00013 22.0 0.2 0.056 13.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK71253.1 - 0.00054 19.4 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK71253.1 - 0.024 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KIK71253.1 - 0.024 14.3 0.0 0.097 12.3 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK71253.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIK71253.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 6PGD PF00393.19 KIK71254.1 - 1.5e-123 411.8 0.0 1.9e-123 411.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIK71254.1 - 1.3e-51 174.9 0.0 1.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK71254.1 - 4e-05 24.1 0.1 7.7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIK71254.1 - 0.0074 16.4 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIK71254.1 - 0.033 13.8 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KIK71254.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxysterol_BP PF01237.18 KIK71255.1 - 2.2e-111 372.3 0.2 7.2e-111 370.6 0.2 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KIK71255.1 - 5e-17 62.0 0.0 1.3e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK71255.1 - 0.00019 21.9 0.8 0.0012 19.4 0.8 2.3 1 1 0 1 1 1 1 PH domain PWI PF01480.17 KIK71256.1 - 1.2e-09 38.3 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KIK71256.1 - 2.4e-06 27.3 1.8 4e-06 26.6 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK71256.1 - 0.00069 19.6 4.6 0.0012 18.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain Glu_syn_central PF04898.14 KIK71256.1 - 0.034 13.6 0.6 1.8 8.0 0.5 2.1 2 0 0 2 2 2 0 Glutamate synthase central domain RRM_3 PF08777.11 KIK71256.1 - 0.041 13.9 0.0 0.041 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 KIK71256.1 - 0.052 13.4 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRKG1_interact PF15898.5 KIK71256.1 - 0.11 13.4 10.1 0.31 11.9 10.1 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 KIK71256.1 - 1.3 8.5 4.8 2 7.9 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ResIII PF04851.15 KIK71257.1 - 5.4e-21 75.3 0.0 1.3e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK71257.1 - 4.8e-18 65.5 0.0 1.4e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK71257.1 - 5.9e-17 62.0 0.0 2.4e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIK71257.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KIK71257.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Trypsin_2 PF13365.6 KIK71258.1 - 4.8e-08 34.0 0.0 9.5e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Proteasome PF00227.26 KIK71259.1 - 2.8e-34 118.3 0.0 3.2e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 KIK71259.1 - 0.031 14.4 0.0 0.38 10.9 0.1 2.3 2 0 0 2 2 2 0 Phage late-transcription coactivator G-patch PF01585.23 KIK71260.1 - 1e-11 44.6 0.5 3e-11 43.0 0.5 1.9 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KIK71260.1 - 1.3e-06 28.5 6.6 2.6e-06 27.5 6.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK71260.1 - 1.4e-05 25.3 1.8 2.9e-05 24.3 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 KIK71260.1 - 1.4e-05 25.1 0.2 1.4e-05 25.1 0.2 2.5 2 0 0 2 2 2 1 G-patch domain zf-C2H2_2 PF12756.7 KIK71260.1 - 0.0008 19.7 0.4 0.0014 18.9 0.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KIK71260.1 - 0.0028 17.8 0.1 0.0041 17.3 0.1 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger DUF4820 PF16091.5 KIK71260.1 - 0.11 11.9 9.7 0.16 11.3 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) zf-DBF PF07535.12 KIK71260.1 - 0.35 11.0 2.7 0.73 10.0 2.7 1.5 1 0 0 1 1 1 0 DBF zinc finger Bromodomain PF00439.25 KIK71261.1 - 1.1e-42 143.9 0.7 6.3e-21 74.2 0.4 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KIK71261.1 - 2e-19 69.5 1.5 4.6e-19 68.4 1.5 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 KIK71261.1 - 0.87 9.6 13.0 0.034 14.1 5.5 2.4 2 1 1 3 3 3 0 FlxA-like protein GBP_C PF02841.14 KIK71261.1 - 2.2 7.6 9.3 1.3 8.4 6.7 1.9 2 1 0 2 2 2 0 Guanylate-binding protein, C-terminal domain WD40 PF00400.32 KIK71262.1 - 6.3e-18 64.8 14.3 0.00027 21.7 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71262.1 - 4.4e-05 23.7 0.2 1.1 9.7 0.0 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK71262.1 - 0.00016 21.6 0.2 0.12 12.3 0.0 3.4 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK71262.1 - 0.00037 19.6 0.1 0.005 15.8 0.0 2.5 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK71262.1 - 0.091 11.3 0.0 0.32 9.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain Frataxin_Cyay PF01491.16 KIK71264.1 - 1.3e-38 131.4 0.0 1.4e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain FAM91_C PF14648.6 KIK71264.1 - 0.047 12.5 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Drf_DAD PF06345.11 KIK71264.1 - 0.22 11.6 2.0 0.59 10.3 2.0 1.7 1 0 0 1 1 1 0 DRF Autoregulatory Domain TFIID_20kDa PF03847.13 KIK71265.1 - 2.6e-27 95.1 0.2 3.8e-27 94.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KIK71265.1 - 5e-05 23.5 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KIK71265.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KIK71265.1 - 0.02 15.2 0.4 0.038 14.4 0.0 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK71265.1 - 0.036 14.2 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Rhodanese PF00581.20 KIK71266.1 - 3.7e-14 53.1 0.0 5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Ctr PF04145.15 KIK71267.1 - 5e-32 111.6 0.0 6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Pilin_N PF07790.11 KIK71267.1 - 1.6 9.7 4.2 3.6 8.6 2.6 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal zf-SCNM1 PF15803.5 KIK71270.1 - 0.24 11.1 1.5 0.68 9.6 1.5 1.8 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Rhodanese PF00581.20 KIK71271.1 - 5.4e-17 62.3 0.0 1.9e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.15 KIK71272.1 - 5.6e-132 440.6 3.5 6.3e-132 440.4 3.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C KH_1 PF00013.29 KIK71273.1 - 3.8e-40 135.5 1.9 2.3e-10 40.2 0.0 7.3 7 0 0 7 7 7 6 KH domain IBR PF01485.21 KIK71274.1 - 2.7e-15 56.3 21.1 7.9e-10 38.8 4.5 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KIK71274.1 - 3.8e-15 56.2 0.6 7.4e-15 55.2 0.6 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KIK71274.1 - 9.7e-06 25.5 9.3 9.7e-06 25.5 9.3 3.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK71274.1 - 7.5e-05 23.0 9.3 7.5e-05 23.0 9.3 4.8 3 2 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KIK71274.1 - 0.00081 19.3 10.3 0.00081 19.3 10.3 4.7 3 2 1 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 KIK71274.1 - 0.013 15.3 9.1 0.013 15.3 9.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 KIK71274.1 - 0.016 15.1 8.1 0.016 15.1 8.1 4.7 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Urb2 PF10441.9 KIK71275.1 - 6.8e-36 124.1 0.1 6.8e-36 124.1 0.1 3.6 3 1 1 4 4 4 1 Urb2/Npa2 family MIF4G PF02854.19 KIK71275.1 - 0.067 12.8 0.0 0.067 12.8 0.0 4.6 5 1 1 6 6 6 0 MIF4G domain Beta_elim_lyase PF01212.21 KIK71276.1 - 4.7e-73 246.0 0.0 6.5e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KIK71276.1 - 8.7e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PI3K_1B_p101 PF10486.9 KIK71278.1 - 1.1 7.0 7.2 1.4 6.6 7.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-met2 PF12907.7 KIK71280.1 - 3.6e-14 52.6 4.6 4.9e-14 52.2 4.6 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KIK71280.1 - 4.1e-08 33.9 13.7 4.1e-08 33.9 13.7 1.7 2 0 0 2 2 2 1 4F5 protein family zf-Tim10_DDP PF02953.15 KIK71281.1 - 5.4e-19 67.6 0.5 6.2e-19 67.4 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ANAPC4_WD40 PF12894.7 KIK71282.1 - 4.7e-09 36.4 0.0 0.0017 18.6 0.0 5.6 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK71282.1 - 3e-07 31.0 28.9 1.3 10.0 0.1 10.5 12 0 0 12 12 12 4 WD domain, G-beta repeat BAT PF15915.5 KIK71282.1 - 0.00055 19.8 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 GAF and HTH_10 associated domain Ge1_WD40 PF16529.5 KIK71282.1 - 0.015 14.3 1.3 6.9 5.5 0.0 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mpv17_PMP22 PF04117.12 KIK71283.1 - 2.3e-23 82.2 0.9 3.7e-23 81.5 0.9 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.16 KIK71285.1 - 1.9e-46 157.2 0.3 2.4e-46 156.8 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PhzC-PhzF PF02567.16 KIK71285.1 - 0.016 14.6 0.2 1.3 8.4 0.1 2.0 1 1 1 2 2 2 0 Phenazine biosynthesis-like protein DEAD PF00270.29 KIK71286.1 - 3.4e-45 154.0 0.0 5.8e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK71286.1 - 1.9e-25 89.4 0.2 9.4e-25 87.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIK71286.1 - 2.9e-19 69.0 0.6 2.9e-19 69.0 0.6 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIK71286.1 - 9.2e-05 22.5 0.9 0.00034 20.7 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK71286.1 - 0.0002 20.7 0.0 0.0002 20.7 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Thioredoxin PF00085.20 KIK71287.1 - 2.1e-26 91.9 0.0 2.6e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK71287.1 - 1.4e-07 31.9 0.1 4e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KIK71287.1 - 2.4e-06 27.3 0.0 2.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KIK71287.1 - 2.5e-05 24.2 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KIK71287.1 - 5.3e-05 23.5 0.0 0.00014 22.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KIK71287.1 - 0.0001 22.1 0.1 0.00075 19.2 0.0 1.9 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 KIK71287.1 - 0.00067 19.1 0.0 0.00071 19.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIK71287.1 - 0.027 14.7 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 KIK71287.1 - 0.041 14.1 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF2847 PF11009.8 KIK71287.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.11 KIK71287.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE UPF0121 PF03661.13 KIK71289.1 - 5.2e-39 134.1 3.7 5.9e-39 133.9 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CBS PF00571.28 KIK71291.1 - 7.6e-32 109.5 6.4 2.3e-09 37.6 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KIK71291.1 - 5.7e-09 35.8 0.0 1.9e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 PB1 domain Hep_59 PF07052.11 KIK71291.1 - 0.13 13.0 1.9 0.16 12.8 0.1 2.0 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Peptidase_C48 PF02902.19 KIK71293.1 - 9.6e-36 123.6 0.4 3.4e-34 118.6 0.4 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HTH_32 PF13565.6 KIK71293.1 - 0.56 10.8 2.9 0.45 11.2 0.4 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Use1 PF09753.9 KIK71294.1 - 0.043 13.5 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Pox_A14 PF05767.12 KIK71295.1 - 0.035 14.2 2.5 0.12 12.6 0.1 2.6 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Ycf4 PF02392.16 KIK71295.1 - 0.038 13.6 0.5 0.074 12.6 0.5 1.4 1 0 0 1 1 1 0 Ycf4 PHO4 PF01384.20 KIK71295.1 - 0.87 8.6 5.0 0.3 10.1 0.8 2.0 2 0 0 2 2 2 0 Phosphate transporter family PTH2 PF01981.16 KIK71296.1 - 1.4e-42 144.7 0.2 2.5e-42 143.9 0.2 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sgf11 PF08209.11 KIK71298.1 - 2.9e-12 45.9 1.1 2.9e-12 45.9 1.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DZR PF12773.7 KIK71298.1 - 0.043 13.9 1.4 0.097 12.7 1.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon SAC3 PF12209.8 KIK71298.1 - 0.085 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain zf-CRD PF17979.1 KIK71298.1 - 0.18 11.9 1.7 6.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Yippee-Mis18 PF03226.14 KIK71299.1 - 5.4e-16 58.7 0.2 5.9e-16 58.6 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.15 KIK71299.1 - 0.0072 16.2 0.5 0.013 15.4 0.5 1.6 1 1 0 1 1 1 1 Recombination endonuclease VII HNH_5 PF14279.6 KIK71299.1 - 0.015 15.1 0.4 0.076 12.9 0.1 1.9 2 0 0 2 2 2 0 HNH endonuclease RIG-I_C-RD PF11648.8 KIK71299.1 - 0.058 13.6 0.5 0.099 12.9 0.5 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Ras PF00071.22 KIK71301.1 - 5.8e-48 162.6 0.0 6.6e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK71301.1 - 3.4e-16 59.6 0.0 5.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIK71301.1 - 0.0015 18.1 0.0 0.0082 15.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK71301.1 - 0.0019 18.1 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KIK71301.1 - 0.0054 16.3 0.1 0.26 10.8 0.0 2.7 1 1 2 3 3 3 1 Ferrous iron transport protein B AAA_25 PF13481.6 KIK71301.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK71301.1 - 0.18 11.5 0.1 0.55 9.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK71301.1 - 0.25 11.7 0.7 0.81 10.0 0.7 2.0 1 1 0 1 1 1 0 AAA ATPase domain PUFD PF16553.5 KIK71302.1 - 0.063 13.4 0.1 0.38 10.9 0.0 2.3 3 1 0 3 3 3 0 BCORL-PCGF1-binding domain F-box-like PF12937.7 KIK71303.1 - 2.9e-11 43.1 0.9 8.9e-11 41.5 0.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK71303.1 - 1.7e-05 24.5 1.5 9.3e-05 22.2 0.3 2.7 2 0 0 2 2 2 1 F-box domain Tim17 PF02466.19 KIK71304.1 - 6.6e-12 45.8 1.8 8.4e-12 45.5 0.9 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KIK71304.1 - 0.31 11.2 3.5 14 5.8 0.1 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Antimicrobial_4 PF08024.11 KIK71306.1 - 0.037 14.1 0.5 0.085 12.9 0.5 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide Enterotoxin_b PF01376.18 KIK71306.1 - 0.044 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain DUF5427 PF10310.9 KIK71307.1 - 2e-61 208.4 4.3 1.5e-56 192.4 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5427) BCAS2 PF05700.11 KIK71308.1 - 3.8e-67 226.0 9.2 4.3e-67 225.8 9.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF1515 PF07439.11 KIK71308.1 - 0.015 15.3 1.8 0.024 14.7 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Mesd PF10185.9 KIK71308.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor HisK_N PF09385.10 KIK71308.1 - 0.055 13.4 0.2 0.087 12.8 0.2 1.2 1 0 0 1 1 1 0 Histidine kinase N terminal LRR_RI_capping PF18779.1 KIK71308.1 - 0.13 11.9 0.3 0.3 10.8 0.3 1.5 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat ZapB PF06005.12 KIK71308.1 - 1.5 9.3 11.1 1.9 9.0 0.6 3.6 3 1 0 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 KIK71308.1 - 2.2 8.8 11.8 0.14 12.7 5.3 2.1 2 1 1 3 3 3 0 Apg6 coiled-coil region Complex1_30kDa PF00329.19 KIK71309.1 - 2.1e-45 154.3 0.0 3.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1682 PF07946.14 KIK71310.1 - 0.0055 16.0 10.7 0.0097 15.1 10.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PEPcase PF00311.17 KIK71310.1 - 0.46 8.5 5.2 0.69 7.9 5.2 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF4746 PF15928.5 KIK71310.1 - 1.1 8.7 14.1 0.046 13.1 7.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4778 PF16008.5 KIK71310.1 - 1.5 8.8 6.4 4.4 7.3 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) GNAT_acetyltr_2 PF13718.6 KIK71310.1 - 1.6 8.1 3.7 1.4 8.3 2.0 1.7 1 1 0 1 1 1 0 GNAT acetyltransferase 2 A2M PF00207.22 KIK71311.1 - 0.071 13.0 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin family ATP-grasp_2 PF08442.10 KIK71312.1 - 1.5e-70 236.9 0.9 3.7e-70 235.6 0.2 1.9 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KIK71312.1 - 7.5e-27 94.0 0.1 1.5e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KIK71312.1 - 1.6e-09 37.5 1.0 1.4e-08 34.5 0.2 2.5 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KIK71312.1 - 0.00041 20.2 0.1 0.0042 16.9 0.0 2.4 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DinB_2 PF12867.7 KIK71313.1 - 1.6e-06 28.6 0.5 2e-06 28.3 0.5 1.1 1 0 0 1 1 1 1 DinB superfamily EpmC PF04315.12 KIK71313.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.5 2 0 0 2 2 2 0 Elongation factor P hydroxylase GTP_EFTU PF00009.27 KIK71314.1 - 1.8e-49 167.9 0.0 2.7e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIK71314.1 - 1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KIK71314.1 - 0.00021 21.4 0.0 0.0011 19.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIK71314.1 - 0.17 12.3 1.3 0.43 11.0 1.3 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Hist_deacetyl PF00850.19 KIK71315.1 - 1.5e-85 287.4 0.0 2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 KIK71315.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 NIL domain DUF4451 PF14616.6 KIK71316.1 - 8.9e-34 116.3 0.5 1.5e-33 115.6 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) FpoO PF10621.9 KIK71316.1 - 0.0039 17.5 0.1 4.3 7.7 0.1 2.4 2 0 0 2 2 2 2 F420H2 dehydrogenase subunit FpoO Ribosomal_S27e PF01667.17 KIK71317.1 - 1.8e-29 101.2 4.6 2.2e-29 100.9 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KIK71317.1 - 0.12 12.3 4.0 0.25 11.4 4.0 1.6 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Mu-like_Com PF10122.9 KIK71317.1 - 0.15 11.5 2.1 4.6 6.8 0.3 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Hexapep PF00132.24 KIK71318.1 - 5.2e-09 35.5 14.8 0.0048 16.6 0.2 3.9 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIK71318.1 - 0.021 14.6 4.5 0.021 14.6 4.5 2.8 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase YkuD PF03734.14 KIK71318.1 - 0.078 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain 4HBT_3 PF13622.6 KIK71319.1 - 4.9e-49 167.8 0.0 7.8e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily XPA_C PF05181.12 KIK71319.1 - 3.3e-23 81.4 1.2 6.2e-23 80.5 1.2 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Acyl_CoA_thio PF02551.15 KIK71319.1 - 2.3e-21 76.0 0.0 5.5e-17 61.8 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA thioesterase XPA_N PF01286.18 KIK71319.1 - 0.0087 16.1 3.9 0.028 14.4 3.9 1.9 1 0 0 1 1 1 1 XPA protein N-terminal RF3_C PF16658.5 KIK71319.1 - 0.073 12.9 0.4 0.17 11.7 0.4 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SH3-WW_linker PF16618.5 KIK71319.1 - 0.2 12.1 6.1 0.41 11.1 6.1 1.5 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 Fungal_trans PF04082.18 KIK71320.1 - 1.1e-14 54.1 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK71320.1 - 0.0018 18.3 12.2 0.0034 17.4 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf_C2H2_10 PF18414.1 KIK71320.1 - 0.23 11.0 0.5 0.46 10.1 0.5 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger BTG PF07742.12 KIK71321.1 - 9.8e-16 57.7 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 BTG family BATS PF06968.13 KIK71323.1 - 7.3e-23 80.5 0.2 2.2e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KIK71323.1 - 1.1e-16 61.6 0.0 1.8e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily BDV_P24 PF06595.11 KIK71324.1 - 0.015 15.2 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 Borna disease virus P24 protein RXT2_N PF08595.11 KIK71324.1 - 0.078 13.0 0.4 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal RIFIN PF02009.16 KIK71325.1 - 0.00011 22.3 1.2 0.00015 21.8 1.2 1.1 1 0 0 1 1 1 1 Rifin SKG6 PF08693.10 KIK71325.1 - 0.0067 15.8 3.1 0.013 14.9 3.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mucin15 PF15672.5 KIK71325.1 - 0.01 15.3 4.8 0.01 15.3 4.8 1.5 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 SARAF PF06682.12 KIK71325.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 KIK71325.1 - 0.013 15.7 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Stevor PF17410.2 KIK71325.1 - 0.037 13.6 3.4 0.052 13.1 3.4 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Rax2 PF12768.7 KIK71325.1 - 0.043 13.3 2.5 0.065 12.7 2.5 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Amnionless PF14828.6 KIK71325.1 - 0.05 12.4 0.2 0.067 12.0 0.2 1.1 1 0 0 1 1 1 0 Amnionless Peptidase_M56 PF05569.11 KIK71325.1 - 0.055 12.7 1.0 0.076 12.2 1.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.6 KIK71325.1 - 0.086 13.7 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KIK71325.1 - 0.12 12.3 5.5 0.24 11.3 5.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 KIK71325.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 KIK71325.1 - 0.24 11.2 4.4 0.46 10.3 4.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD34_antigen PF06365.12 KIK71325.1 - 0.25 10.9 0.1 0.36 10.4 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Sigma_reg_N PF13800.6 KIK71325.1 - 0.28 11.5 2.4 7.3 6.9 0.4 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CD225 PF04505.12 KIK71325.1 - 0.5 10.5 3.9 0.86 9.8 3.9 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein BLM10_mid PF16507.5 KIK71326.1 - 3.4e-178 593.6 0.0 5.2e-178 593.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIK71326.1 - 1e-28 99.1 2.5 6.4e-28 96.5 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIK71326.1 - 0.0037 17.4 13.1 0.76 10.2 0.0 7.2 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 KIK71326.1 - 0.026 14.9 5.6 0.41 11.1 0.0 5.1 6 0 0 6 6 6 0 HEAT repeats MyTH4 PF00784.17 KIK71326.1 - 0.066 13.7 0.0 0.86 10.1 0.0 3.0 2 0 0 2 2 2 0 MyTH4 domain DUF772 PF05598.11 KIK71326.1 - 0.091 12.8 0.1 0.36 10.9 0.1 2.0 1 0 0 1 1 1 0 Transposase domain (DUF772) UME PF08064.13 KIK71326.1 - 0.45 10.4 4.2 11 6.1 0.0 4.6 5 0 0 5 5 5 0 UME (NUC010) domain HEAT_EZ PF13513.6 KIK71326.1 - 1.3 9.6 2.9 29 5.3 0.1 4.6 5 0 0 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIK71326.1 - 5.1 7.8 6.6 27 5.5 0.0 4.8 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DcpS_C PF11969.8 KIK71327.1 - 1.4e-05 25.6 0.0 2.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 KIK71327.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) Translin PF01997.16 KIK71328.1 - 4.3e-63 213.0 0.0 5.1e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Translin family Trigger_C PF05698.14 KIK71328.1 - 0.076 13.0 0.2 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus zf-C3HC4_2 PF13923.6 KIK71330.1 - 1.6e-07 31.0 8.1 2.7e-07 30.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK71330.1 - 2.2e-07 30.6 5.5 3.7e-07 29.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK71330.1 - 2.5e-06 27.7 7.7 4.1e-06 27.0 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK71330.1 - 4.1e-06 26.6 8.8 6.1e-06 26.0 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK71330.1 - 2.4e-05 24.3 5.9 4.4e-05 23.4 4.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK71330.1 - 0.00031 20.8 5.9 0.00053 20.1 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIK71330.1 - 0.00031 20.6 7.0 0.00044 20.1 6.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK71330.1 - 0.0021 17.8 13.2 0.009 15.9 12.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-WRNIP1_ubi PF18279.1 KIK71330.1 - 0.0062 17.1 1.6 0.3 11.8 0.0 2.6 2 0 0 2 2 2 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_6 PF14835.6 KIK71330.1 - 0.068 13.1 8.0 0.12 12.3 8.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 KIK71330.1 - 0.43 10.5 5.7 0.69 9.9 5.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.14 KIK71330.1 - 0.56 10.1 2.7 8 6.4 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KIK71330.1 - 2.1 8.2 9.8 3.9 7.3 7.8 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain 7tm_3 PF00003.22 KIK71331.1 - 0.015 15.0 2.3 0.016 14.9 2.3 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DNA_pol_A_exo1 PF01612.20 KIK71333.1 - 5.3e-05 23.0 0.0 7.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Glyco_hydro_18 PF00704.28 KIK71335.1 - 2.3e-21 76.8 0.1 4.5e-21 75.9 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sporozoite_P67 PF05642.11 KIK71335.1 - 4.1 5.4 10.3 5.5 4.9 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 KIK71336.1 - 1.1e-64 218.3 0.2 1.4e-64 218.0 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71336.1 - 1.1e-19 70.8 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK71336.1 - 2.5e-07 30.8 0.1 2.3e-05 24.4 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK71336.1 - 0.004 16.0 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KIK71336.1 - 0.018 14.6 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIK71336.1 - 0.034 13.5 0.2 0.061 12.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.28 KIK71337.1 - 3.4e-06 27.5 0.0 8.8e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 SET domain DnaJ_C PF01556.18 KIK71338.1 - 8.1e-40 136.3 0.0 1.1e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK71338.1 - 4.2e-23 81.2 4.6 4.6e-23 81.1 3.6 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK71338.1 - 1.1e-08 35.3 18.6 1.1e-08 35.3 18.6 1.8 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 KIK71338.1 - 0.81 9.7 17.0 0.084 12.9 1.6 2.8 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KIK71338.1 - 3.4 7.7 8.5 7.6 6.6 0.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MFS_1 PF07690.16 KIK71339.1 - 1.9e-41 142.2 52.2 3.1e-33 115.1 17.0 3.6 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK71339.1 - 1.8e-10 40.3 9.5 1.8e-10 40.3 9.5 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 KIK71339.1 - 0.0049 17.2 6.2 0.0078 16.5 1.2 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3522) Choline_kinase PF01633.20 KIK71340.1 - 2e-52 177.9 0.0 2.9e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIK71340.1 - 5.3e-11 42.9 0.0 8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-CCCH PF00642.24 KIK71341.1 - 4.4e-19 67.9 13.9 4.8e-11 42.3 2.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK71341.1 - 4.4e-09 36.1 13.6 1.4e-06 28.2 3.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KIK71341.1 - 7.3e-08 32.0 11.2 5.9e-05 22.8 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIK71341.1 - 0.031 14.8 8.4 0.086 13.3 0.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KIK71341.1 - 0.045 14.5 9.2 0.47 11.2 1.3 2.8 1 1 1 2 2 2 0 Torus domain BLM10_mid PF16507.5 KIK71342.1 - 6.2e-184 612.5 0.0 2e-183 610.8 0.0 1.8 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIK71342.1 - 2.3e-32 110.8 0.0 5.5e-31 106.3 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIK71342.1 - 0.00015 21.8 1.5 0.077 13.3 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KIK71342.1 - 0.0017 18.7 0.1 0.16 12.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KIK71342.1 - 0.012 16.1 0.1 0.27 11.8 0.0 3.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KIK71342.1 - 0.043 14.1 0.0 0.55 10.6 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain BLM10_N PF16547.5 KIK71342.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal HEAT_EZ PF13513.6 KIK71342.1 - 0.6 10.7 1.9 12 6.6 0.1 4.3 4 1 1 5 5 5 0 HEAT-like repeat Chalcone_2 PF16035.5 KIK71343.1 - 1.9e-28 99.6 0.7 1.1e-16 61.3 0.0 2.8 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 KIK71343.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.8 1 1 0 1 1 1 1 Chalcone isomerase-like PhyH PF05721.13 KIK71344.1 - 0.0019 18.5 0.1 0.033 14.4 0.1 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Histone PF00125.24 KIK71345.1 - 9.1e-50 168.4 3.0 1e-49 168.2 3.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK71345.1 - 2.7e-05 24.5 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK71345.1 - 5.4e-05 23.3 0.1 9.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KIK71345.1 - 0.00052 20.6 2.0 0.00067 20.3 2.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KIK71345.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KIK71345.1 - 0.089 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIK71345.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TIM21 PF08294.11 KIK71346.1 - 2.4e-22 79.4 0.0 8.1e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 TIM21 ATP-synt_F PF01990.17 KIK71347.1 - 1.6e-33 114.8 0.1 1.9e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 KIK71347.1 - 0.0085 16.0 0.1 0.01 15.7 0.1 1.1 1 0 0 1 1 1 1 PIN like domain Rad21_Rec8_N PF04825.13 KIK71347.1 - 0.093 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein SGT1 PF07093.11 KIK71348.1 - 1.8e-92 310.7 20.1 1.6e-91 307.6 12.8 3.3 2 1 0 2 2 2 2 SGT1 protein Clat_adaptor_s PF01217.20 KIK71349.1 - 1.2e-31 109.5 0.0 1.8e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.14 KIK71350.1 - 3e-41 140.3 0.3 5.2e-41 139.6 0.3 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Fungal_trans PF04082.18 KIK71350.1 - 0.073 12.1 1.4 0.19 10.8 0.3 2.0 1 1 1 2 2 2 0 Fungal specific transcription factor domain Nramp PF01566.18 KIK71351.1 - 2.6e-80 270.1 11.2 1.6e-44 152.4 3.1 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF3082 PF11282.8 KIK71351.1 - 0.33 11.2 5.3 2.9 8.2 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) zf-C2H2 PF00096.26 KIK71352.1 - 2.9e-09 36.9 16.4 9.6e-07 28.9 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK71352.1 - 7.6e-07 29.5 14.2 0.00055 20.5 0.2 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK71352.1 - 4.9e-05 23.2 9.2 0.00089 19.2 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK71352.1 - 0.0022 18.3 1.0 0.11 12.8 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KIK71352.1 - 0.0052 16.9 1.2 1.8 8.8 0.2 2.5 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 KIK71352.1 - 0.03 14.8 16.3 0.041 14.3 2.0 3.7 4 0 0 4 4 4 0 Zinc-finger double domain C5HCH PF17982.1 KIK71352.1 - 5.7 7.2 12.8 2.5 8.3 1.9 3.1 2 1 1 3 3 3 0 NSD Cys-His rich domain zf-H2C2_5 PF13909.6 KIK71352.1 - 6.6 6.6 7.0 14 5.5 2.0 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain MCM PF00493.23 KIK71353.1 - 4.8e-104 346.4 0.0 4.5e-103 343.2 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KIK71353.1 - 1.8e-33 115.1 0.0 4.2e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK71353.1 - 1.3e-30 105.6 0.7 3.5e-30 104.3 0.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK71353.1 - 4.4e-16 59.4 0.1 1e-15 58.2 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK71353.1 - 7.5e-07 28.7 0.0 0.00027 20.4 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIK71353.1 - 4.5e-05 23.5 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIK71353.1 - 0.00018 21.4 0.1 0.0011 18.8 0.1 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KIK71353.1 - 0.032 14.9 0.4 0.32 11.7 0.1 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KIK71353.1 - 0.097 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MitMem_reg PF13012.6 KIK71354.1 - 3.2e-26 92.0 0.1 5.7e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIK71354.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.25 KIK71355.1 - 4.9e-52 176.9 0.0 8.2e-51 172.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71355.1 - 1.2e-35 123.1 0.0 3e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK71355.1 - 8.5e-06 24.8 0.1 2.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIK71355.1 - 0.1 12.5 0.1 0.83 9.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KIK71356.1 - 3.1e-43 148.0 0.0 1.7e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71356.1 - 1.1e-12 47.8 0.0 9e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK71356.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TSA PF03249.13 KIK71356.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen Glyco_hydro_28 PF00295.17 KIK71357.1 - 1.1e-59 202.2 16.1 1.3e-59 201.9 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 KIK71357.1 - 0.00069 18.9 7.7 0.0011 18.3 7.7 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KIK71357.1 - 0.0051 16.2 8.0 0.0076 15.6 7.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) Chlam_PMP PF02415.17 KIK71357.1 - 0.085 13.4 3.1 15 6.3 0.3 3.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pectate_lyase_3 PF12708.7 KIK71357.1 - 0.12 12.2 13.0 1.9 8.3 1.1 3.0 1 1 1 2 2 2 0 Pectate lyase superfamily protein Polysacc_deac_1 PF01522.21 KIK71358.1 - 4.4e-31 107.4 0.1 1e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIK71358.1 - 0.0012 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Secretin_N_2 PF07655.13 KIK71358.1 - 3.4 8.3 18.5 3.1 8.4 2.0 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain NAP PF00956.18 KIK71359.1 - 1.6e-25 89.8 7.6 4.4e-24 85.1 3.8 3.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 KIK71359.1 - 7.4 6.9 9.4 12 6.2 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Syja_N PF02383.18 KIK71360.1 - 2.5e-83 280.0 0.0 3.9e-83 279.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Renin_r PF07850.14 KIK71360.1 - 0.076 13.6 4.2 0.098 13.3 3.1 1.7 2 0 0 2 2 2 0 Renin receptor-like protein LRR_9 PF14580.6 KIK71361.1 - 2.8e-60 202.8 0.7 6.1e-60 201.7 0.2 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KIK71361.1 - 3.1e-12 46.5 12.0 2.3e-06 27.8 3.9 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK71361.1 - 2.4e-09 36.8 8.1 1.2e-08 34.6 4.8 3.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KIK71361.1 - 0.11 13.1 10.3 2.4 9.0 0.1 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KIK71361.1 - 1.8 8.8 7.8 7.2 6.9 0.4 4.2 4 0 0 4 4 4 0 Leucine Rich repeat DUF4149 PF13664.6 KIK71362.1 - 2.4e-25 88.8 2.1 4.9e-25 87.8 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) MFS_1 PF07690.16 KIK71363.1 - 5.3e-13 48.6 20.9 5.3e-13 48.6 20.9 2.2 1 1 2 3 3 3 3 Major Facilitator Superfamily UCR_TM PF02921.14 KIK71364.1 - 1.5e-11 44.6 1.7 5e-11 42.9 1.7 1.9 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KIK71364.1 - 7.3e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Cu-oxidase PF00394.22 KIK71365.1 - 6.4e-47 159.6 0.0 2.1e-40 138.4 0.0 3.1 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK71365.1 - 1.2e-38 131.7 0.2 1.1e-35 122.2 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK71365.1 - 5.3e-38 129.9 2.5 5.3e-32 110.4 0.5 2.9 2 1 0 2 2 2 2 Multicopper oxidase HMG_box PF00505.19 KIK71367.1 - 2.5e-19 69.5 2.0 4.2e-19 68.7 2.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK71367.1 - 8e-15 55.2 0.7 1.4e-14 54.4 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KIK71367.1 - 0.027 15.0 0.1 0.056 14.0 0.0 1.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 B-block_TFIIIC PF04182.12 KIK71368.1 - 6.6e-14 51.8 0.3 2.5e-07 30.7 0.0 4.5 4 0 0 4 4 4 3 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KIK71368.1 - 0.053 13.4 1.3 5.6 6.9 0.0 4.1 4 0 0 4 4 4 0 MarR family PIN_12 PF16289.5 KIK71368.1 - 1.2 9.6 3.3 3.2 8.2 3.3 1.7 1 0 0 1 1 1 0 PIN domain PRELI PF04707.14 KIK71369.1 - 1.2e-37 129.2 0.0 1.4e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family SHS2_Rpb7-N PF03876.17 KIK71370.1 - 1.8e-13 50.6 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KIK71370.1 - 2.4e-11 43.8 0.2 5.6e-11 42.6 0.2 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KIK71370.1 - 0.002 18.4 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 ABC_membrane_2 PF06472.15 KIK71371.1 - 7.9e-85 284.5 0.8 1.1e-84 284.0 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KIK71371.1 - 4.1e-18 66.2 0.0 7.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK71371.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK71371.1 - 0.0047 17.5 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIK71371.1 - 0.026 14.0 0.0 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK71371.1 - 0.032 14.0 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KIK71371.1 - 0.039 13.9 0.3 0.081 12.8 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KIK71371.1 - 0.053 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4258 PF14076.6 KIK71371.1 - 0.067 13.6 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) RsgA_GTPase PF03193.16 KIK71371.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KIK71371.1 - 0.14 12.5 0.1 0.43 10.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIK71371.1 - 0.2 11.3 0.1 0.41 10.3 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain NT5C PF06941.12 KIK71372.1 - 1e-12 48.3 0.4 1e-10 41.8 0.0 2.8 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIF PF03031.18 KIK71372.1 - 5e-05 23.1 0.0 9.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 KIK71372.1 - 8.5e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK71372.1 - 0.0086 16.5 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIK71372.1 - 0.013 15.6 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KIK71372.1 - 0.019 14.6 0.1 0.03 13.9 0.1 1.5 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase PF00702.26 KIK71372.1 - 0.02 15.2 0.0 0.25 11.6 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Amidohydro_2 PF04909.14 KIK71374.1 - 1.3e-22 80.9 0.0 6.6e-18 65.5 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase TatD_DNase PF01026.21 KIK71374.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase Alba PF01918.21 KIK71375.1 - 2.6e-05 24.0 0.0 0.24 11.3 0.0 2.7 2 1 0 2 2 2 2 Alba RRM_occluded PF16842.5 KIK71375.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mis12 PF05859.12 KIK71376.1 - 1.3e-39 135.3 0.6 2.6e-39 134.4 0.2 1.6 2 0 0 2 2 2 1 Mis12 protein Lzipper-MIP1 PF14389.6 KIK71376.1 - 0.0075 16.5 2.2 0.021 15.1 1.1 2.1 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DUF2508 PF10704.9 KIK71376.1 - 0.034 14.3 0.7 0.084 13.1 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) ERp29 PF07749.12 KIK71376.1 - 0.039 14.8 0.3 0.093 13.6 0.3 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain SPATA24 PF15175.6 KIK71376.1 - 0.19 11.6 2.5 0.19 11.6 0.9 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Sugar_tr PF00083.24 KIK71378.1 - 7.8e-114 381.0 25.3 9.3e-114 380.8 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK71378.1 - 8e-25 87.5 25.6 8e-25 87.5 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KIK71379.1 - 4.1e-66 223.0 0.0 8.7e-66 222.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71379.1 - 3.4e-35 121.6 0.0 3.6e-34 118.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK71379.1 - 2e-05 24.1 0.1 0.00012 21.5 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK71379.1 - 0.001 17.9 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK71379.1 - 0.0027 17.7 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK71379.1 - 0.005 15.9 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 KIK71379.1 - 0.015 14.9 0.2 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK71379.1 - 0.093 12.1 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metal_resist PF13801.6 KIK71379.1 - 2.5 8.3 5.9 2.6 8.2 0.2 3.4 4 0 0 4 4 4 0 Heavy-metal resistance MMR_HSR1_Xtn PF16897.5 KIK71380.1 - 1.5e-43 147.1 0.6 2.9e-43 146.2 0.6 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KIK71380.1 - 2.2e-20 72.5 0.0 3.7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KIK71380.1 - 4.7e-17 62.1 0.0 1.3e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK71380.1 - 1.8e-07 30.8 0.0 3.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIK71380.1 - 0.00052 20.1 0.1 0.13 12.3 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 KIK71380.1 - 0.024 13.7 0.0 0.06 12.3 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KIK71380.1 - 0.024 14.9 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KIK71380.1 - 0.035 13.5 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIK71380.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KIK71380.1 - 0.054 13.7 0.2 0.41 10.9 0.0 2.5 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK71380.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 KIK71380.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Lactamase_B_2 PF12706.7 KIK71381.1 - 2.2e-24 86.1 0.0 7.9e-22 77.8 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK71381.1 - 7.9e-06 26.0 0.8 1.6e-05 25.0 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PRELI PF04707.14 KIK71382.1 - 2.8e-34 118.2 0.0 3.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Alpha_adaptin_C PF02296.16 KIK71382.1 - 0.12 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Glyco_transf_28 PF03033.20 KIK71383.1 - 5.5e-30 104.2 0.0 1.1e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KIK71383.1 - 4.8e-28 97.3 1.2 1.1e-15 57.5 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KIK71383.1 - 3.1e-14 53.4 0.2 2.5e-13 50.4 0.2 2.5 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 KIK71383.1 - 2.6e-06 26.5 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.6 KIK71383.1 - 9.1e-05 22.7 0.0 0.00045 20.5 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KIK71383.1 - 0.00012 22.4 0.9 0.016 15.6 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KIK71383.1 - 0.0065 16.7 0.1 0.017 15.4 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SUR7 PF06687.12 KIK71384.1 - 9.6e-22 77.7 9.1 9.6e-22 77.7 9.1 1.4 1 1 1 2 2 2 1 SUR7/PalI family Cadherin_C_2 PF16492.5 KIK71384.1 - 0.069 13.9 2.2 8.2 7.3 1.5 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF5480 PF17576.2 KIK71384.1 - 0.17 11.9 10.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5480) PMP22_Claudin PF00822.20 KIK71384.1 - 0.56 10.1 9.8 0.038 13.9 4.6 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Tetraspanin PF00335.20 KIK71384.1 - 1.3 8.7 8.1 0.16 11.7 3.6 1.7 2 0 0 2 2 2 0 Tetraspanin family RIC1 PF07064.13 KIK71385.1 - 1.2e-100 336.1 1.6 1.6e-100 335.7 1.6 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KIK71385.1 - 0.01 16.1 0.0 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71385.1 - 0.061 13.3 4.4 2.7 8.0 0.1 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DIOX_N PF14226.6 KIK71386.1 - 7e-05 23.6 0.0 0.00014 22.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK71386.1 - 0.011 16.2 0.0 0.057 13.9 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_hydro_72 PF03198.14 KIK71388.1 - 6.5e-88 295.0 0.1 8.8e-88 294.6 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KIK71388.1 - 8.6e-20 71.2 0.5 2.5e-19 69.7 0.5 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KIK71388.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KIK71388.1 - 0.27 10.3 0.1 1.1 8.3 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain RRM_1 PF00076.22 KIK71389.1 - 7e-12 45.0 0.1 1.5e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KIK71389.1 - 2e-05 24.4 0.6 9e-05 22.4 0.2 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIK71389.1 - 0.013 15.2 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ABC_membrane PF00664.23 KIK71390.1 - 4.7e-46 157.6 24.7 8.5e-23 81.4 13.6 3.7 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KIK71390.1 - 5.1e-39 133.9 0.0 5.7e-26 91.7 0.1 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK71390.1 - 1.4e-09 37.7 4.5 0.0055 16.2 0.2 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK71390.1 - 3.8e-06 27.4 0.1 0.16 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK71390.1 - 9e-06 25.7 2.4 0.15 11.8 0.0 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KIK71390.1 - 6.3e-05 23.2 0.4 0.091 12.8 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 KIK71390.1 - 0.00032 21.0 0.0 1.9 8.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KIK71390.1 - 0.00035 20.3 0.8 0.35 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KIK71390.1 - 0.00047 19.8 0.0 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KIK71390.1 - 0.00074 18.7 0.0 0.42 9.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 KIK71390.1 - 0.00081 19.9 0.8 0.043 14.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK71390.1 - 0.0032 17.0 0.1 0.47 9.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KIK71390.1 - 0.0034 16.8 0.4 0.71 9.2 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KIK71390.1 - 0.0058 16.7 1.8 0.88 9.7 0.1 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Pox_A32 PF04665.12 KIK71390.1 - 0.0093 15.4 1.6 1.6 8.1 0.1 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein RsgA_GTPase PF03193.16 KIK71390.1 - 0.011 15.6 0.5 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 KIK71390.1 - 0.02 14.9 0.4 18 5.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIK71390.1 - 0.026 14.4 0.4 1.4 8.8 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Adeno_IVa2 PF02456.15 KIK71390.1 - 0.027 13.3 0.1 2.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 KIK71390.1 - 0.034 14.2 1.5 4.1 7.4 0.1 2.8 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KIK71390.1 - 0.034 13.9 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 KIK71390.1 - 0.039 13.7 0.0 27 4.5 0.0 3.6 3 1 0 3 3 3 0 DEAD/DEAH box helicase Roc PF08477.13 KIK71390.1 - 0.065 13.4 0.1 7.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KIK71390.1 - 0.29 10.8 3.0 0.33 10.6 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain RhoGAP PF00620.27 KIK71391.1 - 2.2e-41 141.2 0.1 8.4e-41 139.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KIK71391.1 - 6.5e-09 35.9 0.6 3.3e-08 33.7 0.6 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain GBP_C PF02841.14 KIK71391.1 - 0.047 13.1 6.0 2.6 7.4 2.8 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain PIF1 PF05970.14 KIK71393.1 - 3.6e-22 79.0 0.3 3.1e-19 69.4 0.1 2.0 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KIK71393.1 - 1.4e-10 41.2 0.0 2.2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK71393.1 - 2.4e-05 24.0 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KIK71393.1 - 4.7e-05 23.8 0.1 7.9e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK71393.1 - 0.00043 20.6 0.5 0.0027 18.0 0.5 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK71393.1 - 0.00069 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KIK71393.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK71393.1 - 0.0013 19.0 0.1 0.0031 17.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KIK71393.1 - 0.0035 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 KIK71393.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KIK71393.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK71393.1 - 0.02 15.3 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KIK71393.1 - 0.021 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KIK71393.1 - 0.025 14.5 0.2 0.059 13.3 0.1 1.7 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 KIK71393.1 - 0.028 14.1 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KIK71393.1 - 0.03 13.6 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIK71393.1 - 0.056 13.1 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 KIK71393.1 - 0.072 13.2 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIK71393.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KIK71393.1 - 0.083 13.4 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Adeno_IVa2 PF02456.15 KIK71393.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.18 KIK71393.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KIK71393.1 - 0.089 12.5 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_32 PF13654.6 KIK71393.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK71393.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK71393.1 - 0.12 12.4 0.1 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 KIK71393.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 KIK71393.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cauli_VI PF01693.16 KIK71394.1 - 2.1e-18 66.3 0.2 3.7e-18 65.6 0.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin PIF1 PF05970.14 KIK71394.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK71394.1 - 2.1e-07 30.9 0.0 2.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK71394.1 - 1.1e-05 25.9 0.0 2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK71394.1 - 0.00012 21.7 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 KIK71394.1 - 0.00086 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.6 KIK71394.1 - 0.0017 18.7 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK71394.1 - 0.0028 16.8 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 KIK71394.1 - 0.0032 16.7 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TrwB_AAD_bind PF10412.9 KIK71394.1 - 0.004 16.1 0.0 0.0054 15.7 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KIK71394.1 - 0.0051 15.8 0.1 0.0075 15.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 KIK71394.1 - 0.0066 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein DUF815 PF05673.13 KIK71394.1 - 0.012 14.7 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 KIK71394.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KIK71394.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KIK71394.1 - 0.018 15.3 0.1 0.049 13.9 0.0 1.8 2 1 2 4 4 1 0 AAA domain NACHT PF05729.12 KIK71394.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIK71394.1 - 0.042 13.6 0.1 0.098 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIK71394.1 - 0.042 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 KIK71394.1 - 0.044 13.9 0.1 1 9.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIK71394.1 - 0.059 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KIK71394.1 - 0.061 13.2 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KIK71394.1 - 0.068 13.2 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 KIK71394.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TsaE PF02367.17 KIK71394.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK71394.1 - 0.095 13.1 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 KIK71394.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MCM PF00493.23 KIK71394.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 KIK71394.1 - 0.16 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.7 KIK71394.1 - 0.19 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.19 KIK71394.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 KIK71395.1 - 7.5e-08 31.9 0.0 8.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF5359 PF17313.2 KIK71395.1 - 0.022 14.7 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5359) Zn_ribbon_17 PF17120.5 KIK71396.1 - 2.3e-06 27.1 3.1 7.7e-06 25.4 3.1 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIK71396.1 - 0.0017 19.2 13.9 0.47 11.4 4.7 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat C1_1 PF00130.22 KIK71396.1 - 0.9 9.5 5.4 3.3 7.7 5.4 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KIK71396.1 - 0.95 9.4 7.8 0.094 12.6 1.2 2.3 2 0 0 2 2 2 0 PHD-finger HscB_4_cys PF18256.1 KIK71396.1 - 5.6 6.9 6.3 3.5 7.5 0.2 2.8 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Ysc84 PF04366.12 KIK71397.1 - 1.8e-34 118.2 0.2 2.7e-34 117.7 0.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KIK71397.1 - 5.9e-16 57.8 0.1 1.3e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK71397.1 - 7.6e-13 47.9 0.1 2.5e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KIK71397.1 - 4.6e-12 45.6 0.0 9.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KIK71397.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) SprB PF13573.6 KIK71398.1 - 0.0068 16.2 0.9 0.028 14.2 0.9 2.1 1 0 0 1 1 1 1 SprB repeat Las1 PF04031.13 KIK71399.1 - 8.2e-46 155.9 0.4 2.8e-45 154.2 0.4 1.9 2 0 0 2 2 2 1 Las1-like T6SS_VasJ PF16989.5 KIK71399.1 - 0.00068 19.2 0.1 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ DUF4231 PF14015.6 KIK71400.1 - 1.7 9.2 7.7 0.17 12.3 1.3 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF4231) DLH PF01738.18 KIK71401.1 - 2.2e-13 50.3 0.0 2.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family YhhN PF07947.14 KIK71402.1 - 0.023 14.3 0.4 0.03 14.0 0.4 1.1 1 0 0 1 1 1 0 YhhN family F-box-like PF12937.7 KIK71403.1 - 3.4e-07 30.0 0.4 8.1e-07 28.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK71403.1 - 0.0081 16.0 0.6 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain Prenylcys_lyase PF07156.14 KIK71404.1 - 2.2e-71 240.9 0.0 3e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KIK71404.1 - 2.8e-12 46.7 0.1 7.7e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK71404.1 - 4.6e-11 42.7 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KIK71404.1 - 1e-05 25.3 0.5 8.1e-05 22.4 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK71404.1 - 2.6e-05 23.6 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK71404.1 - 3.7e-05 23.7 0.1 0.019 14.9 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK71404.1 - 0.0034 16.7 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK71404.1 - 0.017 13.8 0.1 0.14 10.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KIK71404.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KIK71404.1 - 0.088 11.9 0.3 0.3 10.1 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KIK71404.1 - 0.1 11.8 0.1 0.24 10.6 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HIT PF01230.23 KIK71405.1 - 1e-23 83.9 0.1 1.5e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK71405.1 - 2.7e-12 47.1 0.1 3.7e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIK71405.1 - 0.064 13.1 1.7 0.17 11.8 1.7 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Ammonium_transp PF00909.21 KIK71406.1 - 1.4e-118 396.1 23.7 1.6e-118 395.9 23.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phosphorylase PF00343.20 KIK71408.1 - 1.8e-289 962.0 0.0 2.2e-289 961.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase HA70_C PF17993.1 KIK71408.1 - 0.0016 18.5 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 2 Haemagglutinin 70 C-terminal domain LSM14 PF12701.7 KIK71409.1 - 5.5e-24 84.1 0.0 1.2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KIK71409.1 - 0.00029 20.9 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 KIK71409.1 - 0.018 15.0 6.6 0.022 14.8 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FDF PF09532.10 KIK71409.1 - 5.7 7.9 12.7 1.1 10.2 6.8 2.6 2 1 0 2 2 2 0 FDF domain C2 PF00168.30 KIK71411.1 - 1.9e-88 291.5 3.7 1.8e-18 66.7 0.0 5.8 6 0 0 6 6 6 5 C2 domain MMM1 PF10296.9 KIK71411.1 - 0.032 13.3 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 MLVIN_C PF18697.1 KIK71411.1 - 0.051 13.7 0.1 0.39 10.8 0.0 2.5 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Mito_carr PF00153.27 KIK71412.1 - 6.2e-20 70.9 0.0 2.2e-06 27.5 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein NUDIX PF00293.28 KIK71413.1 - 9.7e-06 25.7 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SET PF00856.28 KIK71414.1 - 1.9e-09 38.1 0.0 1.7e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.19 KIK71416.1 - 3.5e-05 23.7 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NAD_binding_10 PF13460.6 KIK71417.1 - 8.5e-27 94.2 0.0 9.8e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK71417.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIK71417.1 - 6.5e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK71417.1 - 0.00046 19.3 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIK71417.1 - 0.0047 16.1 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KIK71417.1 - 0.035 14.5 0.0 0.07 13.6 0.0 1.5 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Macro PF01661.21 KIK71417.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Macro domain NmrA PF05368.13 KIK71419.1 - 1.7e-28 99.8 0.0 1.8e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK71419.1 - 9.1e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NPL4 PF05021.15 KIK71420.1 - 1.1e-98 330.4 0.0 1.5e-98 329.9 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KIK71420.1 - 1e-63 213.8 0.2 1.5e-63 213.3 0.2 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KIK71420.1 - 1.9e-05 25.0 0.0 3.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 KIK71420.1 - 0.0012 18.1 1.6 0.0012 18.1 1.6 1.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 KIK71420.1 - 0.22 11.3 1.9 0.47 10.2 1.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KIK71420.1 - 8 6.6 7.8 0.31 11.1 0.4 2.4 3 0 0 3 3 3 0 Double zinc ribbon bZIP_2 PF07716.15 KIK71421.1 - 2e-08 34.2 9.7 7.2e-08 32.4 9.6 2.0 1 1 1 2 2 2 2 Basic region leucine zipper CCDC85 PF10226.9 KIK71421.1 - 0.00088 19.0 1.1 0.00088 19.0 1.1 2.3 3 0 0 3 3 3 1 CCDC85 family bZIP_1 PF00170.21 KIK71421.1 - 0.0039 17.3 4.5 0.01 15.9 4.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor CHCH PF06747.13 KIK71422.1 - 7.8e-07 29.1 5.9 1.1e-06 28.6 5.9 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KIK71422.1 - 0.0027 18.0 5.3 0.012 15.9 5.3 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KIK71422.1 - 0.0064 16.5 4.8 0.011 15.8 4.8 1.4 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KIK71422.1 - 0.012 15.3 1.4 0.015 15.0 1.4 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KIK71422.1 - 0.16 12.1 4.9 1.6 8.8 5.0 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KIK71422.1 - 0.21 11.9 4.4 2.3 8.6 4.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GDPD PF03009.17 KIK71423.1 - 1.1e-30 107.3 0.0 1.5e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIK71423.1 - 5.6e-05 23.5 0.4 0.0055 17.1 0.5 2.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RINT1_TIP1 PF04437.13 KIK71424.1 - 3.1e-93 313.4 0.0 8e-93 312.0 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family SPAR_C PF11881.8 KIK71424.1 - 0.16 11.9 2.5 0.14 12.0 0.6 1.8 2 1 0 2 2 2 0 C-terminal domain of SPAR protein MCM PF00493.23 KIK71425.1 - 2.6e-94 314.5 0.0 3.6e-94 314.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK71425.1 - 4.8e-32 110.5 0.0 8.4e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK71425.1 - 1.9e-23 82.7 1.0 3.7e-23 81.8 1.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK71425.1 - 9.8e-12 45.4 0.0 2.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK71425.1 - 7.7e-08 32.0 0.1 1.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK71425.1 - 0.0029 17.5 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK71425.1 - 0.018 14.8 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 KIK71425.1 - 0.13 12.3 0.0 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NuDC PF16273.5 KIK71425.1 - 0.67 10.5 11.3 6.8 7.3 9.6 2.6 2 0 0 2 2 2 0 Nuclear distribution C domain WD40 PF00400.32 KIK71427.1 - 5.7e-32 109.3 17.5 1.2e-09 38.7 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71427.1 - 2e-08 34.4 0.2 0.18 12.1 0.1 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK71427.1 - 0.00053 19.6 0.1 0.07 12.7 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK71427.1 - 0.00078 18.1 0.0 0.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain NESP55 PF06390.12 KIK71427.1 - 0.062 12.9 1.4 0.1 12.2 1.4 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pkinase PF00069.25 KIK71428.1 - 2.8e-72 243.2 0.0 4.9e-72 242.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71428.1 - 1.5e-52 178.4 0.0 2.3e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK71428.1 - 2e-05 23.6 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK71428.1 - 0.00024 20.5 0.0 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 KIK71428.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 KIK71428.1 - 0.0082 15.1 0.0 0.27 10.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain TPMT PF05724.11 KIK71429.1 - 1.3e-29 103.5 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KIK71429.1 - 3.8e-09 37.1 0.0 7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK71429.1 - 5.4e-09 36.6 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK71429.1 - 7.3e-06 25.9 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK71429.1 - 0.00022 21.1 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK71429.1 - 0.003 18.3 0.0 0.0067 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KIK71430.1 - 1.7e-31 109.6 0.0 2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KIK71430.1 - 3.2e-09 37.3 0.0 5.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK71430.1 - 8.3e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK71430.1 - 1.1e-07 32.4 0.0 6.4e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK71430.1 - 8.7e-06 25.7 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK71430.1 - 1.3e-05 25.8 0.0 2.6e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MFS_1 PF07690.16 KIK71431.1 - 2.3e-30 105.7 27.2 2.3e-30 105.7 27.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Adaptin_N PF01602.20 KIK71432.1 - 7.3e-104 348.2 3.3 9.4e-104 347.8 3.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK71432.1 - 3.7e-11 43.3 4.9 9.5e-09 35.5 0.0 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK71432.1 - 1.1e-06 28.9 2.3 0.015 15.7 0.1 4.3 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 KIK71432.1 - 2.9e-06 27.1 1.3 0.42 11.0 0.0 6.0 6 0 0 6 6 5 1 HEAT repeat RTP1_C1 PF10363.9 KIK71432.1 - 0.0014 18.8 1.8 0.15 12.3 0.0 3.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KIK71432.1 - 0.0095 15.5 0.2 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II API5 PF05918.11 KIK71432.1 - 0.039 12.8 0.0 0.039 12.8 0.0 2.7 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.6 KIK71432.1 - 0.081 13.5 2.4 2.3 8.8 0.0 4.4 5 1 2 7 7 6 0 HEAT-like repeat Gemini_V2 PF01524.17 KIK71432.1 - 0.15 12.3 0.1 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Geminivirus V2 protein V-ATPase_H_C PF11698.8 KIK71432.1 - 1.1 9.4 5.1 83 3.3 1.3 4.0 3 1 1 4 4 4 0 V-ATPase subunit H TIP120 PF08623.10 KIK71432.1 - 2.3 8.0 6.1 5.4 6.8 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DUF4519 PF15012.6 KIK71432.1 - 4.1 7.6 6.2 11 6.2 6.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Zn_clus PF00172.18 KIK71433.1 - 0.00062 19.8 9.8 0.089 12.9 1.2 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM176 PF14851.6 KIK71433.1 - 0.84 9.3 6.4 1.7 8.3 6.4 1.5 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.18 KIK71433.1 - 3.9 7.3 12.4 18 5.1 12.4 1.9 1 1 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 KIK71433.1 - 5.9 5.1 10.4 6.9 4.8 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 KIK71434.1 - 0.07 11.6 1.2 0.11 10.9 1.2 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 KIK71434.1 - 0.38 9.0 4.2 0.62 8.3 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein ArdA PF07275.11 KIK71434.1 - 0.83 10.2 3.7 9.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Antirestriction protein (ArdA) bZIP_2 PF07716.15 KIK71434.1 - 4.3 7.5 8.3 7.1 6.8 0.3 2.9 1 1 1 2 2 2 0 Basic region leucine zipper Y_phosphatase PF00102.27 KIK71436.1 - 3.6e-36 124.9 0.0 3.1e-17 62.9 0.0 3.4 3 1 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK71436.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate RNA_capsid PF03035.14 KIK71436.1 - 3.5 7.6 5.2 0.75 9.8 1.7 1.6 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein UCH PF00443.29 KIK71437.1 - 1.6e-39 136.0 0.0 1.7e-38 132.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KIK71437.1 - 7.4e-17 61.0 0.0 1.6e-14 53.5 0.0 2.6 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KIK71437.1 - 4.7e-08 33.0 0.5 0.002 17.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DivIC PF04977.15 KIK71437.1 - 0.15 11.9 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KIK71437.1 - 0.33 11.5 1.8 1 9.9 1.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region MscS_porin PF12795.7 KIK71437.1 - 2.5 7.6 4.9 16 4.9 0.1 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Glyco_transf_11 PF01531.16 KIK71440.1 - 0.052 12.7 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 O-FucT PF10250.9 KIK71440.1 - 0.084 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase UPF0242 PF06785.11 KIK71441.1 - 0.023 14.8 2.3 0.03 14.5 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KIK71441.1 - 0.16 10.6 0.2 0.19 10.3 0.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 KIK71441.1 - 0.62 10.5 7.6 1.3 9.5 7.4 1.6 1 1 0 1 1 1 0 Cell division protein ZapB p450 PF00067.22 KIK71442.1 - 6.1e-72 242.8 0.0 1.1e-71 242.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF465 PF04325.13 KIK71442.1 - 0.035 14.1 0.2 0.075 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Ank_4 PF13637.6 KIK71443.1 - 1.5e-10 41.4 0.2 1.5e-05 25.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK71443.1 - 1.6e-09 38.2 2.0 5.4e-09 36.5 2.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK71443.1 - 4.7e-09 36.3 4.3 0.00036 20.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK71443.1 - 4.4e-06 26.6 0.7 0.13 12.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK71443.1 - 6.6e-06 26.3 0.2 0.0066 16.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) FLgD_tudor PF13861.6 KIK71443.1 - 0.0079 16.4 2.7 2 8.7 0.1 2.4 3 0 0 3 3 3 2 FlgD Tudor-like domain DUF3447 PF11929.8 KIK71443.1 - 0.037 14.0 0.0 15 5.6 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) DUF555 PF04475.12 KIK71443.1 - 0.043 14.1 0.1 3.8 7.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF555) Coatomer_b_Cpla PF14806.6 KIK71443.1 - 0.09 12.8 0.2 0.94 9.5 0.0 1.9 1 1 1 2 2 2 0 Coatomer beta subunit appendage platform Transketolase_N PF00456.21 KIK71444.1 - 2.3e-14 53.1 0.6 3.9e-13 49.1 0.6 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KIK71444.1 - 3.5e-06 26.9 0.0 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 KIK71444.1 - 8e-05 21.7 0.0 0.00024 20.1 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KIK71444.1 - 0.00052 19.7 0.2 0.0013 18.5 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KIK71444.1 - 0.0015 18.3 0.1 0.0069 16.2 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain G_path_suppress PF15991.5 KIK71447.1 - 0.24 11.5 0.5 0.41 10.7 0.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor Cytadhesin_P30 PF07271.11 KIK71448.1 - 0.66 9.5 4.8 0.98 8.9 4.8 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Glyco_hydro_28 PF00295.17 KIK71449.1 - 1.3e-42 146.0 1.8 2.2e-42 145.3 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIK71449.1 - 0.00029 20.7 21.0 0.0062 16.4 18.4 2.6 1 1 1 2 2 2 2 Right handed beta helix region Glyco_hydro_28 PF00295.17 KIK71450.1 - 3.8e-46 157.7 3.8 5.6e-46 157.1 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIK71450.1 - 3e-05 23.9 24.2 0.00023 21.0 19.1 2.7 1 1 1 2 2 2 2 Right handed beta helix region Histone PF00125.24 KIK71451.1 - 1e-49 168.2 3.9 1.1e-49 168.1 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK71451.1 - 2.5e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK71451.1 - 9.6e-05 22.5 1.2 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK71451.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIK71451.1 - 0.002 18.8 2.1 0.0025 18.4 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIK71451.1 - 0.082 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIK71451.1 - 0.095 12.8 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PAF PF15715.5 KIK71453.1 - 0.044 14.4 1.4 0.052 14.1 0.8 1.5 1 1 0 1 1 1 0 PCNA-associated factor histone like domain HEM4 PF02602.15 KIK71454.1 - 5.6e-30 104.4 0.0 8.1e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD zf-C2H2 PF00096.26 KIK71455.1 - 2.3e-10 40.3 13.9 1.3e-05 25.3 2.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK71455.1 - 4.6e-05 23.6 7.3 4.6e-05 23.6 7.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK71455.1 - 7.3e-05 23.3 12.9 0.014 16.2 3.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK71455.1 - 0.0015 19.1 4.2 0.058 14.0 0.3 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIK71455.1 - 0.0027 17.9 2.5 0.0036 17.6 2.5 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KIK71455.1 - 0.02 15.3 2.6 0.29 11.6 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK71455.1 - 0.028 14.7 1.3 0.028 14.7 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 KIK71455.1 - 0.06 13.3 1.5 0.68 10.0 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_aberr PF17017.5 KIK71455.1 - 5.1 7.2 10.7 57 3.8 3.0 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger EF-hand_1 PF00036.32 KIK71456.1 - 1.6e-26 89.8 20.0 5e-10 38.2 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK71456.1 - 2.8e-26 91.8 15.5 5.1e-13 49.3 5.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK71456.1 - 7.8e-22 75.3 15.2 9.2e-09 34.5 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIK71456.1 - 4e-17 61.8 12.0 3e-08 33.4 1.9 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KIK71456.1 - 4.4e-13 48.1 11.9 2.5e-06 26.7 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KIK71456.1 - 2.2e-11 43.9 2.4 5.3e-05 23.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIK71456.1 - 2.5e-07 30.6 9.5 0.00062 19.7 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KIK71456.1 - 0.00015 21.7 2.4 0.054 13.4 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 KIK71456.1 - 0.0044 17.2 0.6 0.71 10.1 0.6 2.3 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_14 PF17959.1 KIK71456.1 - 0.025 14.9 4.0 0.99 9.8 0.6 2.4 2 1 0 2 2 2 0 EF-hand domain DUF150 PF02576.17 KIK71456.1 - 0.048 14.1 0.3 3 8.3 0.2 2.4 1 1 1 2 2 2 0 RimP N-terminal domain SPARC_Ca_bdg PF10591.9 KIK71456.1 - 0.058 13.7 4.7 1.8 8.9 0.3 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1636 PF07845.11 KIK71456.1 - 0.14 12.6 0.0 5.4 7.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1636) Com_YlbF PF06133.11 KIK71456.1 - 0.18 12.4 4.7 3 8.5 1.0 2.9 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA zf-MYND PF01753.18 KIK71457.1 - 4.6 7.4 8.1 18 5.5 8.1 2.0 1 1 0 1 1 1 0 MYND finger Glyco_hydro_35 PF01301.19 KIK71458.1 - 2.4e-72 244.3 0.1 3.6e-72 243.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIK71458.1 - 2.8e-57 192.2 1.5 2.6e-31 108.5 0.1 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIK71458.1 - 7.8e-34 117.1 2.3 1.4e-33 116.2 2.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIK71458.1 - 1.7e-19 69.2 0.1 4.3e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.14 KIK71458.1 - 0.051 13.4 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase DUF4453 PF14627.6 KIK71458.1 - 0.072 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) zf-C2H2 PF00096.26 KIK71460.1 - 8.7e-11 41.7 12.8 2.6e-05 24.4 1.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK71460.1 - 3.2e-06 27.5 11.6 0.00084 20.0 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK71460.1 - 1.5e-05 25.5 2.6 0.013 16.1 0.4 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIK71460.1 - 6.5e-05 23.2 3.7 6.5e-05 23.2 3.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIK71460.1 - 0.019 15.0 1.0 0.019 15.0 1.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIK71460.1 - 0.36 11.0 5.5 10 6.2 1.7 2.1 1 1 0 2 2 2 0 Aberrant zinc-finger zf-BED PF02892.15 KIK71460.1 - 1.7 8.7 8.1 10 6.2 1.6 2.9 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 KIK71460.1 - 1.8 8.4 10.8 1.1 9.1 3.5 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type ING PF12998.7 KIK71461.1 - 2.7e-12 47.2 0.1 5.2e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIK71461.1 - 3.4e-08 33.3 5.6 5.4e-08 32.6 5.6 1.3 1 0 0 1 1 1 1 PHD-finger Lzipper-MIP1 PF14389.6 KIK71461.1 - 0.0019 18.5 3.8 0.56 10.6 0.3 3.0 2 1 1 3 3 3 2 Leucine-zipper of ternary complex factor MIP1 CCDC24 PF15669.5 KIK71461.1 - 0.06 13.2 0.2 0.06 13.2 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-HC5HC2H PF13771.6 KIK71461.1 - 0.082 13.2 1.7 0.19 12.0 1.7 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain Trypan_PARP PF05887.11 KIK71461.1 - 5 7.1 9.4 0.11 12.5 2.0 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Homeodomain PF00046.29 KIK71462.1 - 6.5e-18 64.3 4.6 1.3e-17 63.4 4.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK71462.1 - 1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain TT_ORF2 PF02957.15 KIK71462.1 - 1.5 9.8 4.0 0.52 11.2 0.3 2.1 2 1 0 2 2 2 0 TT viral ORF2 DUF1749 PF08538.10 KIK71463.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) S1-P1_nuclease PF02265.16 KIK71464.1 - 3.8e-61 207.1 0.0 8e-61 206.0 0.0 1.5 1 1 0 1 1 1 1 S1/P1 Nuclease RdRP PF05183.12 KIK71465.1 - 3.4e-88 296.8 0.0 6.4e-88 295.9 0.0 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase ASFV_J13L PF05568.11 KIK71466.1 - 2.4 7.9 5.6 11 5.7 0.6 2.5 2 0 0 2 2 2 0 African swine fever virus J13L protein COX7a PF02238.15 KIK71467.1 - 0.023 15.1 0.6 0.023 15.1 0.6 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Polysacc_deac_1 PF01522.21 KIK71468.1 - 6.5e-06 26.1 0.1 1.5e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase MFS_1 PF07690.16 KIK71469.1 - 3.9e-10 39.2 30.1 3.9e-10 39.2 30.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK71469.1 - 1.6e-06 27.9 4.0 1.6e-06 27.9 4.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KIK71470.1 - 1e-08 34.5 30.8 1e-08 34.5 30.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK71470.1 - 6.1e-05 22.8 4.3 6.1e-05 22.8 4.3 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DAP PF15228.6 KIK71471.1 - 0.0029 18.7 0.1 0.0029 18.7 0.1 2.3 1 1 0 2 2 2 1 Death-associated protein Aldo_ket_red PF00248.21 KIK71472.1 - 7.8e-71 238.6 0.2 8.9e-71 238.5 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyridox_ox_2 PF12900.7 KIK71472.1 - 0.099 12.6 0.3 10 6.1 0.1 2.5 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF5100 PF17029.5 KIK71472.1 - 0.18 11.7 0.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) S1-P1_nuclease PF02265.16 KIK71473.1 - 4.1e-66 223.4 0.0 8.3e-66 222.4 0.0 1.4 1 1 0 1 1 1 1 S1/P1 Nuclease bZIP_2 PF07716.15 KIK71474.1 - 0.014 15.4 11.2 0.024 14.7 11.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 KIK71474.1 - 0.036 14.1 8.0 0.059 13.5 8.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_DNAp_acc PF04929.12 KIK71474.1 - 1.3 7.9 3.7 1.8 7.4 3.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BTB PF00651.31 KIK71475.1 - 0.0066 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 KIK71476.1 - 1.4e-63 214.8 0.0 1.5e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71476.1 - 9.6e-30 103.7 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK71476.1 - 0.00077 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK71476.1 - 0.0039 16.5 0.0 0.0065 15.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK71476.1 - 0.019 13.9 0.2 0.032 13.2 0.2 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KIK71476.1 - 0.053 12.9 0.3 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK71476.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBM_21 PF03370.13 KIK71477.1 - 4.1e-16 59.1 0.0 9.5e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIK71477.1 - 2.9e-06 27.8 0.0 1.2e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) F-box-like PF12937.7 KIK71478.1 - 8.2e-06 25.6 0.3 8.2e-06 25.6 0.3 2.4 2 0 0 2 2 2 1 F-box-like CBM_21 PF03370.13 KIK71480.1 - 2e-22 79.5 0.0 3.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIK71480.1 - 4.6e-05 23.9 0.5 8.6e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) KRAB PF01352.27 KIK71480.1 - 0.075 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 KRAB box Malic_M PF03949.15 KIK71481.1 - 1.6e-87 293.0 0.0 2.1e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIK71481.1 - 1.9e-57 194.0 0.0 2.7e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2673 PF10880.8 KIK71483.1 - 0.073 13.2 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DUF812 PF05667.11 KIK71483.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Zn_clus PF00172.18 KIK71487.1 - 0.019 15.1 8.7 0.032 14.4 8.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KIK71488.1 - 4.9e-193 642.6 0.0 5.9e-193 642.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK71488.1 - 2.2e-12 46.5 0.0 9.9e-11 41.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KIK71488.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain LemA PF04011.12 KIK71488.1 - 0.02 14.7 1.0 0.042 13.7 1.0 1.5 1 0 0 1 1 1 0 LemA family StbA PF06406.11 KIK71488.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 StbA protein GLE1 PF07817.13 KIK71488.1 - 0.039 13.1 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 GLE1-like protein Peptidase_A4 PF01828.17 KIK71489.1 - 1.2e-26 93.5 0.6 8.6e-26 90.7 0.6 1.9 1 1 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.17 KIK71490.1 - 1.7e-32 112.6 0.1 2.4e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family Sec8_exocyst PF04048.14 KIK71491.1 - 0.023 14.6 0.1 0.023 14.6 0.1 3.6 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain RRN3 PF05327.11 KIK71491.1 - 0.19 10.2 3.9 0.31 9.5 3.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATG16 PF08614.11 KIK71491.1 - 4.7 7.4 31.9 0.035 14.3 3.6 3.6 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4663 PF15668.5 KIK71493.1 - 0.18 10.8 2.8 0.28 10.2 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Methyltransf_16 PF10294.9 KIK71494.1 - 7.2e-16 58.4 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIK71494.1 - 0.00066 20.3 0.0 0.0043 17.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK71494.1 - 0.0017 19.1 0.0 0.0058 17.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK71494.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK71494.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIK71494.1 - 0.04 13.3 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KIK71494.1 - 0.041 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Chitin_synth_2 PF03142.15 KIK71495.1 - 7.1e-280 929.1 0.0 9.1e-280 928.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK71495.1 - 1e-12 48.4 0.9 3.1e-12 46.8 0.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK71495.1 - 7.1e-10 39.2 0.1 2e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIK71495.1 - 2.3e-05 23.9 0.1 0.0016 17.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KIK71495.1 - 0.0058 16.5 0.0 0.061 13.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 BTB_2 PF02214.22 KIK71496.1 - 0.092 13.1 0.0 1.1 9.6 0.0 2.4 2 1 0 2 2 2 0 BTB/POZ domain MoCF_biosynth PF00994.24 KIK71498.1 - 0.098 12.3 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Probable molybdopterin binding domain DUF401 PF04165.12 KIK71499.1 - 0.0063 15.9 1.0 0.0063 15.9 1.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF401) YtpI PF14007.6 KIK71499.1 - 0.083 13.0 2.2 1.9 8.7 0.4 2.5 2 0 0 2 2 2 0 YtpI-like protein PKS_DE PF18369.1 KIK71499.1 - 0.11 13.1 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain DUF2834 PF11196.8 KIK71499.1 - 1.9 8.9 9.9 0.14 12.5 1.7 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2834) Voltage_CLC PF00654.20 KIK71500.1 - 0.0012 18.2 4.0 0.0012 18.2 4.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel Claudin_3 PF06653.11 KIK71500.1 - 0.29 11.1 4.0 0.8 9.6 4.0 1.7 1 0 0 1 1 1 0 Tight junction protein, Claudin-like NADH_dh_m_C1 PF15088.6 KIK71500.1 - 1.8 8.2 3.4 9.3 6.0 0.1 2.5 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial RRM_1 PF00076.22 KIK71505.1 - 8e-23 80.1 0.2 3.5e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK71505.1 - 2.5e-12 46.5 0.0 8.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK71505.1 - 2e-06 27.6 0.0 0.00072 19.4 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KIK71505.1 - 0.014 15.4 0.3 0.15 12.1 0.1 2.5 2 2 0 2 2 2 0 Limkain b1 PfkB PF00294.24 KIK71506.1 - 1.8e-62 211.4 0.0 2.1e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2855 PF11017.8 KIK71508.1 - 5.4e-97 325.6 0.6 6.3e-97 325.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Aminotran_5 PF00266.19 KIK71510.1 - 4.8e-16 58.7 0.0 8.3e-16 57.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIK71510.1 - 4.5e-06 26.1 0.0 7.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIK71510.1 - 0.032 13.6 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_2 PF00891.18 KIK71511.1 - 1.8e-22 79.7 0.0 5.2e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain RPA_C PF08784.11 KIK71511.1 - 0.2 12.3 0.2 1.2 9.9 0.0 2.1 1 1 1 2 2 2 0 Replication protein A C terminal FlgN PF05130.12 KIK71512.1 - 0.0031 18.0 5.5 0.0057 17.2 5.5 1.3 1 0 0 1 1 1 1 FlgN protein LMP PF04778.12 KIK71512.1 - 0.047 13.6 5.6 0.092 12.7 5.6 1.4 1 0 0 1 1 1 0 LMP repeated region Cauli_VI PF01693.16 KIK71513.1 - 0.001 19.3 1.8 0.062 13.6 0.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin Filament PF00038.21 KIK71513.1 - 0.96 9.0 4.8 1.3 8.5 4.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein KDZ PF18758.1 KIK71514.1 - 6.1e-66 222.2 0.0 1.1e-65 221.4 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK71514.1 - 5.7e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases BST2 PF16716.5 KIK71514.1 - 0.069 13.7 0.4 0.31 11.6 0.4 2.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 CxC3 PF18804.1 KIK71514.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DUF3040 PF11239.8 KIK71514.1 - 0.16 12.3 0.5 0.51 10.7 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Abhydrolase_1 PF00561.20 KIK71516.1 - 1.6e-10 41.0 0.0 2.4e-09 37.2 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK71516.1 - 2.7e-06 28.2 0.0 4.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK71516.1 - 0.0026 17.3 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KIK71516.1 - 0.019 14.2 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 AMP-binding PF00501.28 KIK71517.1 - 4.8e-23 81.4 0.0 5.2e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Lum_binding PF00677.17 KIK71517.1 - 0.04 13.9 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 Lumazine binding domain Glyco_hydro_59 PF02057.15 KIK71518.1 - 1.9e-15 56.9 3.3 2.8e-15 56.3 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 CBM_1 PF00734.18 KIK71518.1 - 1.4e-12 47.3 5.5 1.4e-12 47.3 5.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydr_30_2 PF14587.6 KIK71518.1 - 6.2e-11 42.5 8.1 2.8e-10 40.3 0.2 2.3 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KIK71518.1 - 1.2e-09 38.2 8.0 4.2e-09 36.5 8.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 KIK71518.1 - 9.3e-08 31.4 0.1 1.2e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain SPX PF03105.19 KIK71519.1 - 0.12 12.3 10.6 0.15 12.0 10.6 1.1 1 0 0 1 1 1 0 SPX domain Pneumo_att_G PF05539.11 KIK71519.1 - 0.43 10.1 11.6 0.6 9.6 11.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Nop10p PF04135.12 KIK71521.1 - 8.7e-22 76.9 0.3 1e-21 76.7 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Thioredoxin PF00085.20 KIK71522.1 - 1.1e-28 99.2 0.2 1.3e-28 99.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK71522.1 - 2.4e-09 37.6 0.2 1.1e-08 35.4 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK71522.1 - 2.8e-06 27.5 0.0 0.0033 17.7 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KIK71522.1 - 3.6e-06 26.8 0.1 4.2e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KIK71522.1 - 2.6e-05 23.7 0.1 2.9e-05 23.6 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KIK71522.1 - 7.3e-05 22.7 0.0 9.2e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK71522.1 - 7.5e-05 22.5 0.0 0.0094 15.7 0.0 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 KIK71522.1 - 0.00039 20.5 0.0 0.00051 20.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like E3_binding PF02817.17 KIK71523.1 - 0.023 15.0 0.4 0.059 13.7 0.4 1.6 1 0 0 1 1 1 0 e3 binding domain sCache_3_2 PF17203.4 KIK71523.1 - 0.075 13.2 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Single cache domain 3 TauD PF02668.16 KIK71524.1 - 6e-45 154.1 0.1 7.6e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPR_9 PF13371.6 KIK71525.1 - 0.00073 19.6 0.2 0.0035 17.5 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK71525.1 - 0.043 13.9 2.4 0.36 11.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK71525.1 - 0.077 12.8 0.9 1.7 8.6 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 KIK71526.1 - 2.3e-153 511.0 0.0 2.7e-153 510.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KIK71526.1 - 7e-15 55.3 0.0 1.6e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KIK71526.1 - 4.6e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF3314 PF11771.8 KIK71526.1 - 0.03 14.4 0.1 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) Cu-oxidase PF00394.22 KIK71527.1 - 7e-37 127.0 1.3 8.1e-37 126.8 0.2 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK71527.1 - 7.8e-30 103.4 0.5 1.3e-28 99.5 0.1 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK71527.1 - 4.7e-28 97.6 2.9 5.3e-27 94.2 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase RTA1 PF04479.13 KIK71528.1 - 3.3e-53 180.4 11.6 4e-53 180.1 11.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Isochorismatase PF00857.20 KIK71529.1 - 7.7e-28 97.8 0.0 1.6e-27 96.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family MINDY_DUB PF04424.13 KIK71531.1 - 9.2e-27 93.4 0.0 1.7e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase CRAL_TRIO PF00650.20 KIK71533.1 - 8.8e-39 132.8 0.0 1.2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK71533.1 - 3.4e-05 23.9 0.2 7.2e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIK71533.1 - 0.0094 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain G-alpha PF00503.20 KIK71535.1 - 2.6e-113 378.8 0.0 3.3e-113 378.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK71535.1 - 2.7e-12 46.5 0.1 7.6e-09 35.3 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIK71535.1 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KIK71535.1 - 0.0014 18.9 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK71535.1 - 0.0054 16.4 0.0 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KIK71535.1 - 0.011 15.3 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KIK71535.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KIK71535.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family 2OG-FeII_Oxy_3 PF13640.6 KIK71536.1 - 2.1e-11 44.5 0.0 3.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.21 KIK71537.1 - 2.8e-22 79.4 0.0 7.1e-22 78.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK71537.1 - 2e-11 44.1 0.0 3.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK71537.1 - 2.7e-11 43.0 0.0 3.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK71537.1 - 4.8e-10 39.1 0.0 7.6e-08 31.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK71537.1 - 1.7e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK71537.1 - 0.00047 19.4 0.1 0.0011 18.2 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIK71537.1 - 0.0025 16.9 0.0 0.0085 15.2 0.0 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 KIK71537.1 - 0.0032 17.1 0.1 0.0053 16.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK71537.1 - 0.02 14.4 0.1 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DUF1378 PF07125.11 KIK71537.1 - 0.07 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) CorA PF01544.18 KIK71539.1 - 4e-33 115.0 12.2 1e-29 103.8 10.0 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein NACHT PF05729.12 KIK71540.1 - 5.1e-14 52.5 0.1 8.3e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK71540.1 - 1.3e-06 28.9 1.3 1.9e-06 28.4 0.2 1.8 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KIK71540.1 - 0.00023 21.2 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK71540.1 - 0.00077 19.8 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK71540.1 - 0.0011 19.3 0.0 0.0029 18.0 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA PF00004.29 KIK71540.1 - 0.0019 18.6 0.0 0.019 15.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK71540.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK71540.1 - 0.012 15.6 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0489 PF12640.7 KIK71540.1 - 0.017 15.3 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 UPF0489 domain KAP_NTPase PF07693.14 KIK71540.1 - 0.023 13.9 0.6 4.2 6.5 0.2 2.6 1 1 1 2 2 2 0 KAP family P-loop domain Cytidylate_kin PF02224.18 KIK71540.1 - 0.049 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase APS_kinase PF01583.20 KIK71540.1 - 0.053 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK71540.1 - 0.055 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 KIK71540.1 - 0.082 12.8 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KIK71540.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 KIK71540.1 - 0.13 11.6 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KIK71540.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KIK71540.1 - 0.19 12.2 0.0 8.7 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK71540.1 - 0.2 12.2 0.0 0.42 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK71542.1 - 2e-14 53.8 0.1 4.9e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK71542.1 - 1.1e-05 25.9 0.0 2.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK71542.1 - 0.00089 19.6 0.0 0.0052 17.1 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KIK71542.1 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK71542.1 - 0.008 16.6 0.1 0.084 13.3 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK71542.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KIK71542.1 - 0.026 13.8 0.3 14 4.8 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain AAA_25 PF13481.6 KIK71542.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK71542.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIK71542.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK71542.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase adh_short PF00106.25 KIK71543.1 - 2.2e-37 128.5 0.1 2.7e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK71543.1 - 8.2e-30 104.1 0.1 1.1e-29 103.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK71543.1 - 3.8e-10 40.0 0.1 5.7e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK71543.1 - 0.012 14.9 0.1 0.64 9.3 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KIK71543.1 - 0.073 12.8 0.2 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 KIK71543.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PfkB PF00294.24 KIK71544.1 - 7.4e-69 232.4 2.9 8.4e-69 232.2 2.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peripla_BP_6 PF13458.6 KIK71544.1 - 0.017 14.8 2.4 0.42 10.2 0.1 2.7 3 0 0 3 3 3 0 Periplasmic binding protein DUF364 PF04016.12 KIK71544.1 - 0.082 12.5 0.0 15 5.2 0.0 2.8 3 0 0 3 3 3 0 Putative heavy-metal chelation RMMBL PF07521.12 KIK71544.1 - 0.097 12.6 0.0 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Aldo_ket_red PF00248.21 KIK71545.1 - 1.3e-72 244.5 0.2 1.5e-72 244.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK71546.1 - 3.7e-66 223.3 0.0 4.2e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK71548.1 - 2e-71 240.6 0.2 2.2e-71 240.4 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK71549.1 - 8.8e-73 245.0 0.3 1e-72 244.9 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyridox_ox_2 PF12900.7 KIK71549.1 - 0.21 11.6 0.3 27 4.7 0.1 2.6 1 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KIK71550.1 - 2.3e-21 76.3 0.0 6.8e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KIK71550.1 - 0.004 17.3 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BrnA_antitoxin PF14384.6 KIK71550.1 - 0.14 12.7 1.1 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system zf-C2H2 PF00096.26 KIK71552.1 - 2.7e-09 37.0 4.5 0.00028 21.2 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK71552.1 - 2.9e-08 33.9 2.5 0.00014 22.4 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK71552.1 - 1.3e-05 25.3 1.3 0.016 15.4 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK71552.1 - 0.00029 20.8 0.8 0.0039 17.1 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIK71552.1 - 0.012 16.0 0.4 0.41 11.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OrsD PF12013.8 KIK71552.1 - 0.68 10.4 3.0 0.71 10.3 0.7 2.2 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Enolase_C PF00113.22 KIK71553.1 - 1.2e-145 484.3 0.1 1.6e-145 483.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KIK71553.1 - 7.9e-59 197.5 0.1 1.2e-58 196.9 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KIK71553.1 - 9.6e-07 28.6 0.0 2.2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KIK71553.1 - 0.0019 17.4 0.2 0.0043 16.2 0.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Epimerase PF01370.21 KIK71554.1 - 1.1e-15 57.8 0.0 1.4e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK71554.1 - 1.2e-10 41.3 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIK71554.1 - 4.1e-07 29.3 0.0 5.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIK71554.1 - 1.7e-06 27.3 0.0 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIK71554.1 - 1.3e-05 24.5 0.0 0.0057 15.8 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 KIK71554.1 - 0.072 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK71554.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 KR domain MAP65_ASE1 PF03999.12 KIK71555.1 - 2.3e-70 238.0 0.0 3.5e-62 211.0 0.0 2.8 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Exonuc_VII_L PF02601.15 KIK71555.1 - 0.39 10.2 4.1 1.2 8.7 0.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit SKA2 PF16740.5 KIK71555.1 - 0.48 10.2 6.8 10 6.0 0.5 3.4 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Apolipoprotein PF01442.18 KIK71555.1 - 7.7 6.3 14.0 1.1 9.1 1.3 3.3 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain UvrD_C PF13361.6 KIK71556.1 - 2.5e-08 33.7 0.0 8e-07 28.7 0.0 2.9 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIK71556.1 - 5e-08 32.8 0.2 1.2e-06 28.3 0.0 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KIK71556.1 - 1.7e-07 31.6 0.0 5.4e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK71556.1 - 8.6e-07 28.7 0.0 0.01 15.6 0.1 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain TPR_2 PF07719.17 KIK71556.1 - 0.0013 18.7 13.4 0.1 12.8 0.2 5.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK71556.1 - 0.003 17.3 8.3 0.35 10.8 0.2 4.2 3 1 2 5 5 5 4 Tetratricopeptide repeat Clathrin PF00637.20 KIK71556.1 - 0.0045 16.9 2.0 0.027 14.4 0.1 3.1 3 1 0 3 3 3 1 Region in Clathrin and VPS AAA_30 PF13604.6 KIK71556.1 - 0.0065 16.2 0.2 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK71556.1 - 0.0072 16.6 0.1 0.034 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KIK71556.1 - 0.085 12.5 0.0 0.3 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.6 KIK71556.1 - 0.13 12.4 7.0 0.52 10.5 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 KIK71556.1 - 3.1 7.1 12.7 0.53 9.7 3.7 2.8 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KIK71556.1 - 4 8.3 6.7 8.9 7.2 0.4 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Ribonuc_L-PSP PF01042.21 KIK71557.1 - 3.5e-42 143.2 0.0 3.9e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP G-alpha PF00503.20 KIK71558.1 - 4e-115 384.8 0.0 4.7e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK71558.1 - 5.8e-11 42.2 0.0 1.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIK71558.1 - 0.00097 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 KIK71558.1 - 0.0043 17.5 0.0 0.0078 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK71558.1 - 0.0078 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KIK71558.1 - 0.015 14.8 0.0 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK71558.1 - 0.018 15.3 0.0 6.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KIK71558.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 KIK71558.1 - 0.042 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Glyco_hydro_53 PF07745.13 KIK71558.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Paramyxo_NS_C PF02725.14 KIK71559.1 - 0.058 13.5 0.1 0.058 13.5 0.1 1.8 2 0 0 2 2 2 0 Non-structural protein C SesA PF17107.5 KIK71559.1 - 0.42 10.8 4.8 6.3 7.0 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ferritin_2 PF13668.6 KIK71562.1 - 3.6e-18 66.1 0.0 5.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 KIK71563.1 - 8.6e-130 433.6 11.1 9.8e-130 433.4 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK71563.1 - 4.9e-21 75.0 34.4 8.8e-14 51.2 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIK71564.1 - 0.002 18.0 0.4 0.017 15.0 0.4 2.7 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK71565.1 - 0.0087 16.5 5.9 2.8 8.5 0.1 5.3 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) DUF5110 PF17137.4 KIK71566.1 - 0.15 12.4 0.1 23 5.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) Alpha-L-AF_C PF06964.12 KIK71567.1 - 1.2e-33 116.6 0.1 2.2e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KIK71567.1 - 0.00014 22.1 1.8 0.00076 19.8 1.8 2.2 1 1 0 1 1 1 1 Carbohydrate binding domain Lipase_GDSL_2 PF13472.6 KIK71568.1 - 0.00098 19.6 0.1 0.0016 18.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ABC_tran PF00005.27 KIK71569.1 - 1.5e-50 171.3 0.0 7.2e-24 84.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KIK71569.1 - 7.5e-20 71.3 54.2 2.4e-11 43.3 29.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KIK71569.1 - 5.1e-19 69.2 0.2 1.6e-05 24.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK71569.1 - 4.5e-08 33.8 1.2 0.011 16.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KIK71569.1 - 1.4e-06 27.9 1.7 0.78 9.1 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIK71569.1 - 3.4e-06 27.1 0.4 0.051 13.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KIK71569.1 - 8.9e-06 25.4 0.5 0.049 13.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK71569.1 - 2.6e-05 24.1 0.5 0.4 10.3 0.0 3.4 4 0 0 4 4 4 2 AAA ATPase domain DUF4162 PF13732.6 KIK71569.1 - 0.0025 18.5 0.1 2.5 8.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) SRP54 PF00448.22 KIK71569.1 - 0.0033 17.1 1.2 2.4 7.7 0.1 2.8 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_27 PF13514.6 KIK71569.1 - 0.0034 17.0 0.1 0.65 9.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIK71569.1 - 0.0067 16.4 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KIK71569.1 - 0.013 15.2 5.3 1.2 8.8 0.1 3.5 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 KIK71569.1 - 0.028 13.5 0.2 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIK71569.1 - 0.035 13.4 0.1 2.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 KIK71569.1 - 0.054 13.8 2.6 3 8.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain MukB PF04310.12 KIK71569.1 - 0.06 13.1 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_28 PF13521.6 KIK71569.1 - 0.31 11.2 1.7 14 5.9 0.6 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK71569.1 - 0.78 9.4 2.6 20 4.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KIK71569.1 - 0.91 10.0 2.3 14 6.1 0.2 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DASH_Ask1 PF08655.10 KIK71572.1 - 2.4e-06 27.3 0.1 4.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 NACHT PF05729.12 KIK71573.1 - 1.8e-13 50.8 0.1 3e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK71573.1 - 1.5e-07 32.0 0.4 4.1e-07 30.5 0.2 1.8 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KIK71573.1 - 5.5e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK71573.1 - 5.7e-05 23.5 0.0 0.00044 20.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK71573.1 - 7.7e-05 23.0 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK71573.1 - 0.0028 17.7 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK71573.1 - 0.0038 17.6 0.0 0.02 15.3 0.0 2.2 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 KIK71573.1 - 0.038 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK71573.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.14 KIK71573.1 - 0.12 11.6 1.9 8.3 5.5 0.6 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 KIK71573.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIK71573.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase DASH_Ask1 PF08655.10 KIK71574.1 - 7.3e-25 86.6 0.1 1.3e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 TMEM171 PF15471.6 KIK71574.1 - 1.2 8.1 2.9 2 7.3 2.9 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DNA_pol_phi PF04931.13 KIK71574.1 - 1.7 6.7 5.6 2.4 6.2 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Dus PF01207.17 KIK71575.1 - 1.5e-47 162.2 0.1 2.6e-47 161.4 0.1 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1180 PF06679.12 KIK71577.1 - 0.0027 18.2 0.1 0.0035 17.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF2207 PF09972.9 KIK71577.1 - 0.0073 15.1 0.0 0.0081 15.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Amnionless PF14828.6 KIK71577.1 - 0.024 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless MGC-24 PF05283.11 KIK71577.1 - 0.042 14.3 1.2 0.09 13.2 1.2 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 KIK71577.1 - 0.09 12.7 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.16 KIK71577.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KIK71577.1 - 0.16 12.8 0.0 0.34 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 KIK71577.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.0 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 KIK71578.1 - 0.014 16.2 0.0 0.022 15.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KIK71578.1 - 0.05 12.3 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTP_tm PF18861.1 KIK71578.1 - 0.14 12.1 1.1 0.28 11.2 1.2 1.5 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Syndecan PF01034.20 KIK71578.1 - 0.27 11.2 0.3 0.51 10.3 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain AHL_synthase PF17327.2 KIK71580.1 - 0.0094 15.0 1.2 2.3 7.2 0.0 2.1 2 0 0 2 2 2 2 Acyl homoserine lactone synthase DUF1685 PF07939.11 KIK71580.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Dimer_Tnp_hAT PF05699.14 KIK71581.1 - 3.5e-11 42.7 0.0 3.7e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4895 PF16236.5 KIK71585.1 - 0.05 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4895) DASH_Hsk3 PF08227.11 KIK71586.1 - 0.087 13.2 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Skp1 PF01466.19 KIK71588.1 - 3.4e-26 91.1 2.4 5.8e-26 90.4 2.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK71588.1 - 3.5e-23 81.6 0.1 1.1e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain F-box-like PF12937.7 KIK71594.1 - 1.9e-06 27.7 2.4 5.5e-06 26.2 2.4 1.9 1 0 0 1 1 1 1 F-box-like UCR_6-4kD PF08997.10 KIK71594.1 - 0.12 12.3 0.2 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein YadA_anchor PF03895.15 KIK71596.1 - 0.035 14.2 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 YadA-like membrane anchor domain PIF1 PF05970.14 KIK71596.1 - 0.04 13.1 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 KIK71597.1 - 2.4e-06 27.4 0.0 2.7e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK71597.1 - 6.8e-06 25.5 0.1 7e-06 25.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KIK71597.1 - 0.00059 20.2 0.0 0.00065 20.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK71597.1 - 0.004 16.9 0.0 0.0042 16.8 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_21 PF13304.6 KIK71597.1 - 0.0049 16.7 0.1 0.0051 16.7 0.1 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK71597.1 - 0.0083 15.8 0.0 0.0087 15.8 0.0 1.4 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK71597.1 - 0.022 15.1 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KIK71597.1 - 0.039 12.7 0.0 0.041 12.7 0.0 1.0 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_18 PF13238.6 KIK71597.1 - 0.04 14.5 0.0 0.04 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK71597.1 - 0.043 13.2 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 KIK71597.1 - 0.083 12.3 0.0 0.092 12.2 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK71597.1 - 0.089 13.2 0.0 0.089 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KIK71597.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Guanylate_kin PF00625.21 KIK71597.1 - 0.19 11.4 0.0 0.23 11.1 0.0 1.2 1 1 0 1 1 1 0 Guanylate kinase Lon_2 PF13337.6 KIK71597.1 - 0.25 9.8 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Helitron_like_N PF14214.6 KIK71598.1 - 3.1e-26 92.8 0.0 3.9e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Glyco_transf_8 PF01501.20 KIK71602.1 - 2e-16 60.3 0.0 2.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KIK71602.1 - 0.0044 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 BTK PF00779.19 KIK71603.1 - 0.087 12.7 1.0 0.23 11.3 1.0 1.7 1 0 0 1 1 1 0 BTK motif EphA2_TM PF14575.6 KIK71604.1 - 0.0032 18.3 0.0 0.0065 17.3 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KIK71604.1 - 0.0054 15.5 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 KIK71604.1 - 0.0061 15.9 0.1 0.016 14.6 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_Coat_B PF05356.11 KIK71604.1 - 0.028 14.3 0.8 0.051 13.5 0.1 1.7 2 0 0 2 2 2 0 Phage Coat protein B TMEM51 PF15345.6 KIK71604.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Alpha_GJ PF03229.13 KIK71604.1 - 0.051 14.1 1.0 0.051 14.1 1.0 2.2 3 0 0 3 3 3 0 Alphavirus glycoprotein J TMEM154 PF15102.6 KIK71604.1 - 0.29 11.0 2.3 0.54 10.1 1.6 2.0 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KIK71605.1 - 0.0034 18.2 0.0 0.0066 17.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK71605.1 - 0.0055 15.6 0.0 0.0081 15.0 0.0 1.2 1 0 0 1 1 1 1 Amnionless Herpes_gE PF02480.16 KIK71605.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 KIK71605.1 - 0.038 13.8 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 BatA PF07584.11 KIK71605.1 - 0.065 13.6 0.2 0.16 12.4 0.2 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal TMEM154 PF15102.6 KIK71605.1 - 0.12 12.2 2.0 0.53 10.2 2.0 2.0 1 1 0 1 1 1 0 TMEM154 protein family Glyco_hydro_47 PF01532.20 KIK71607.1 - 1.1e-151 505.9 0.0 1.2e-151 505.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MS_channel PF00924.18 KIK71607.1 - 0.11 12.1 0.0 8.6 5.8 0.0 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel LAGLIDADG_2 PF03161.13 KIK71607.1 - 0.16 12.0 0.1 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family DNase_II PF03265.15 KIK71607.1 - 0.22 10.8 0.5 0.41 9.9 0.5 1.4 1 0 0 1 1 1 0 Deoxyribonuclease II WD40 PF00400.32 KIK71610.1 - 1.3e-83 272.6 22.8 9.7e-10 38.9 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71610.1 - 2.7e-35 120.5 0.1 0.00024 21.4 0.0 7.9 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71610.1 - 1.3e-20 72.8 0.1 0.24 11.4 0.0 8.4 8 0 0 8 8 8 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71610.1 - 8.8e-12 44.6 5.2 0.43 9.5 0.0 7.7 1 1 7 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK71610.1 - 1.8e-09 36.5 0.0 1.9 6.7 0.0 7.0 4 1 2 7 7 7 3 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK71610.1 - 8.7e-09 35.1 0.0 0.33 10.2 0.0 6.6 6 1 1 7 7 7 1 WD40-like domain Gmad1 PF10647.9 KIK71610.1 - 1.2e-08 35.1 5.8 0.029 14.1 0.4 5.4 1 1 3 4 4 4 2 Lipoprotein LpqB beta-propeller domain CHAP PF05257.16 KIK71610.1 - 1.7e-08 34.9 3.5 5 7.8 0.1 7.1 1 1 5 8 8 8 2 CHAP domain Proteasome_A_N PF10584.9 KIK71610.1 - 2.2e-07 30.4 8.7 33 4.3 0.0 8.6 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.6 KIK71610.1 - 9e-06 25.4 2.5 0.00073 19.2 0.5 3.1 1 1 1 2 2 2 1 PQQ-like domain DHFR_2 PF06442.11 KIK71610.1 - 2e-05 24.3 1.9 4 7.3 0.0 6.0 2 2 5 7 7 7 1 R67 dihydrofolate reductase Nup160 PF11715.8 KIK71610.1 - 0.00038 19.2 0.0 3.9 6.0 0.0 4.8 3 1 3 6 6 6 1 Nucleoporin Nup120/160 DUF5018 PF16410.5 KIK71610.1 - 0.0093 14.7 0.0 0.017 13.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5018) FeThRed_A PF02941.15 KIK71610.1 - 0.037 14.2 0.1 87 3.4 0.0 4.5 2 2 3 6 6 6 0 Ferredoxin thioredoxin reductase variable alpha chain Emaravirus_P4 PF16505.5 KIK71610.1 - 0.058 12.4 0.3 1.5 7.7 0.0 3.5 6 1 1 7 7 7 0 P4 movement protein of Emaravirus, and the 30K superfamily PQQ PF01011.21 KIK71610.1 - 0.077 13.0 0.0 15 5.7 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK71610.1 - 2.8 8.7 7.1 14 6.5 0.1 4.8 6 1 0 7 7 6 0 Cuticle protein Amastin PF07344.11 KIK71611.1 - 0.026 14.4 0.1 0.029 14.2 0.1 1.0 1 0 0 1 1 1 0 Amastin surface glycoprotein AAA_16 PF13191.6 KIK71612.1 - 2.3e-05 24.9 0.1 4.1e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK71612.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KIK71612.1 - 0.0018 17.5 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KIK71612.1 - 0.0023 17.7 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KIK71612.1 - 0.007 16.9 0.0 0.0089 16.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIK71612.1 - 0.0076 16.7 0.4 0.037 14.4 0.4 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KIK71612.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK71612.1 - 0.042 13.0 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIK71612.1 - 0.049 13.6 1.3 0.22 11.4 1.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIK71612.1 - 0.095 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK71612.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK71612.1 - 0.12 11.6 1.4 0.29 10.4 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 KIK71612.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Sigma54_activat PF00158.26 KIK71612.1 - 0.16 11.6 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain WD40 PF00400.32 KIK71614.1 - 1.4e-136 440.3 45.6 2.8e-10 40.6 0.1 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71614.1 - 4.3e-54 180.8 9.0 0.00022 21.5 0.0 14.4 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71614.1 - 2.4e-30 103.8 7.1 2 8.4 0.0 14.6 14 0 0 14 14 14 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71614.1 - 2.5e-18 66.1 5.5 1.6 7.6 0.0 12.6 1 1 12 14 14 14 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK71614.1 - 1.6e-13 51.0 0.0 0.04 13.8 0.0 5.9 1 1 5 6 6 6 4 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK71614.1 - 2.7e-11 42.5 0.0 11 4.2 0.0 10.8 5 4 4 11 11 11 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK71614.1 - 2.8e-08 34.3 0.1 1.2e-07 32.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain WD40_like PF17005.5 KIK71614.1 - 5.5e-08 32.5 0.0 9.1 5.5 0.0 8.1 8 2 2 10 10 10 0 WD40-like domain PQQ PF01011.21 KIK71614.1 - 8.6e-07 28.6 0.0 10 6.2 0.0 8.7 11 0 0 11 11 11 0 PQQ enzyme repeat NACHT PF05729.12 KIK71614.1 - 2e-06 27.8 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Peptidase_S9_N PF02897.15 KIK71614.1 - 3.4e-06 26.1 0.2 0.63 8.8 0.0 5.4 4 1 1 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA PF00004.29 KIK71614.1 - 0.0004 20.8 0.3 0.0032 17.9 0.0 2.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Proteasome_A_N PF10584.9 KIK71614.1 - 0.00041 20.0 25.1 43 3.9 0.0 12.5 14 0 0 14 14 14 0 Proteasome subunit A N-terminal signature DUF815 PF05673.13 KIK71614.1 - 0.0042 16.3 0.3 0.32 10.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIK71614.1 - 0.036 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK71614.1 - 0.038 14.4 0.0 7.9 6.9 0.0 3.9 5 0 0 5 5 3 0 RNA helicase AAA_7 PF12775.7 KIK71614.1 - 0.048 13.2 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK71614.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KIK71614.1 - 0.061 13.9 0.0 1.4 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK71614.1 - 0.068 12.3 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Vps8 PF12816.7 KIK71614.1 - 0.088 12.3 0.2 0.4 10.2 0.1 2.1 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 Cuticle_4 PF15955.5 KIK71614.1 - 0.31 11.8 11.7 1.5e+02 3.2 0.0 7.6 9 0 0 9 9 9 0 Cuticle protein WD40 PF00400.32 KIK71615.1 - 5.6e-51 169.4 15.9 2.8e-09 37.4 0.0 6.1 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71615.1 - 1.7e-23 82.7 0.2 0.0013 19.0 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71615.1 - 4.2e-14 52.0 0.8 0.25 11.3 0.0 6.4 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK71615.1 - 3.3e-09 35.6 0.0 0.033 12.5 0.0 4.9 2 1 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KIK71615.1 - 1.1e-07 31.9 0.0 6.6e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK71615.1 - 1.3e-07 30.9 0.9 1.6 7.6 0.0 5.3 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK71615.1 - 4.5e-07 29.5 0.0 0.32 10.3 0.0 4.4 4 1 0 5 5 5 2 WD40-like domain DHFR_2 PF06442.11 KIK71615.1 - 0.00028 20.7 2.2 2.2 8.2 0.1 4.2 2 1 3 5 5 5 2 R67 dihydrofolate reductase Cytochrom_D1 PF02239.16 KIK71615.1 - 0.001 17.7 0.0 0.017 13.7 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KIK71615.1 - 0.0021 17.7 8.4 29 4.4 0.0 6.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF5122 PF17164.4 KIK71615.1 - 0.0081 16.4 1.0 73 3.8 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller AAA_7 PF12775.7 KIK71616.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KIK71616.1 - 0.00051 19.3 0.0 0.00058 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KIK71616.1 - 0.00069 19.4 0.0 0.00084 19.1 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KIK71616.1 - 0.01 16.4 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK71616.1 - 0.019 15.3 0.0 0.022 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Parvo_NS1 PF01057.17 KIK71616.1 - 0.035 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK71616.1 - 0.053 13.9 0.1 0.092 13.2 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIK71616.1 - 0.076 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KIK71616.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_15 PF13175.6 KIK71616.1 - 0.16 11.6 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK71616.1 - 0.17 11.0 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KIK71616.1 - 0.23 10.7 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Sec2p PF06428.11 KIK71618.1 - 0.00017 21.5 5.2 0.0019 18.1 0.3 2.3 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p Cast PF10174.9 KIK71618.1 - 0.0012 17.2 0.6 0.0012 17.2 0.6 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HMMR_N PF15905.5 KIK71618.1 - 0.0013 18.3 4.0 0.0016 18.0 4.0 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KIK71618.1 - 0.002 18.3 0.7 0.0031 17.7 0.7 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Transcrip_act PF04949.13 KIK71618.1 - 0.0034 17.3 0.1 0.0044 16.9 0.1 1.1 1 0 0 1 1 1 1 Transcriptional activator LRS4 PF10422.9 KIK71618.1 - 0.0038 16.8 2.4 0.0043 16.7 2.4 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 FAM76 PF16046.5 KIK71618.1 - 0.014 14.8 0.7 0.014 14.8 0.7 1.1 1 0 0 1 1 1 0 FAM76 protein Peptidase_S49_N PF08496.10 KIK71618.1 - 0.017 15.2 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GAS PF13851.6 KIK71618.1 - 0.022 14.1 3.8 0.038 13.3 2.2 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 KIK71618.1 - 0.025 14.6 6.2 1.2 9.2 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KIK71618.1 - 0.035 14.1 1.1 0.053 13.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KIK71618.1 - 0.042 13.7 3.2 1.6 8.7 0.0 3.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_GP20 PF06810.11 KIK71618.1 - 0.052 13.3 1.3 0.1 12.4 1.3 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Med9 PF07544.13 KIK71618.1 - 0.067 13.3 4.0 0.31 11.2 0.1 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 KIK71618.1 - 0.079 12.2 1.0 0.12 11.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 KIK71618.1 - 0.087 13.0 5.4 0.33 11.1 5.5 1.8 1 1 0 1 1 1 0 Tropomyosin like Csm1_N PF18504.1 KIK71618.1 - 0.16 12.3 4.9 3.4 8.1 0.9 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KIK71618.1 - 0.25 11.5 3.0 2.1 8.5 0.1 2.5 2 1 0 2 2 2 0 bZIP transcription factor DUF4335 PF14233.6 KIK71619.1 - 0.014 15.3 1.2 0.022 14.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Amidinotransf PF02274.17 KIK71619.1 - 0.043 12.9 1.0 0.061 12.4 1.0 1.2 1 0 0 1 1 1 0 Amidinotransferase UPF0242 PF06785.11 KIK71619.1 - 0.11 12.6 5.0 0.19 11.8 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 KIK71619.1 - 0.3 10.8 3.6 2.5 7.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Retrotrans_gag PF03732.17 KIK71620.1 - 2.5e-07 30.9 0.0 3.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK71620.1 - 0.0018 18.2 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Exonuc_VII_S PF02609.16 KIK71621.1 - 0.19 11.8 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Exonuclease VII small subunit WD40 PF00400.32 KIK71622.1 - 3.8e-122 394.6 45.5 1.3e-08 35.3 0.1 14.6 15 0 0 15 15 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71622.1 - 2.8e-59 197.4 7.1 0.00095 19.4 0.0 14.1 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71622.1 - 1.8e-31 107.4 18.8 0.71 9.9 0.0 13.6 13 0 0 13 13 13 11 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71622.1 - 6.3e-18 64.8 15.0 1.1 8.1 0.0 12.7 1 1 12 13 13 13 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK71622.1 - 1.4e-14 53.3 0.0 0.91 7.8 0.0 9.4 4 2 4 9 9 9 5 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK71622.1 - 4.5e-13 48.5 0.1 0.0018 16.9 0.0 4.9 1 1 1 5 5 5 4 Cytochrome D1 heme domain DHFR_2 PF06442.11 KIK71622.1 - 1.9e-08 34.0 2.6 23 4.9 0.0 10.0 4 3 8 12 12 11 0 R67 dihydrofolate reductase WD40_like PF17005.5 KIK71622.1 - 5.8e-07 29.1 0.0 17 4.6 0.0 7.4 5 3 4 9 9 9 0 WD40-like domain Nup160 PF11715.8 KIK71622.1 - 2.6e-06 26.4 0.2 7.9 5.0 0.0 6.8 5 3 3 10 10 10 0 Nucleoporin Nup120/160 NACHT PF05729.12 KIK71622.1 - 5.6e-06 26.4 0.0 9.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain FeThRed_A PF02941.15 KIK71622.1 - 0.00013 22.1 4.1 50 4.1 0.0 7.5 5 2 4 9 9 9 0 Ferredoxin thioredoxin reductase variable alpha chain Nbas_N PF15492.6 KIK71622.1 - 0.00028 20.3 13.4 15 4.8 0.0 8.8 1 1 9 11 11 11 0 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 KIK71622.1 - 0.0031 17.9 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK71622.1 - 0.0054 17.2 0.4 0.035 14.5 0.4 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK71622.1 - 0.026 13.7 0.4 0.092 11.9 0.0 1.9 2 1 0 2 2 2 0 NB-ARC domain Proteasome_A_N PF10584.9 KIK71622.1 - 0.039 13.7 36.0 45 3.9 0.0 12.8 14 0 0 14 14 13 0 Proteasome subunit A N-terminal signature Zeta_toxin PF06414.12 KIK71622.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2540 PF10802.8 KIK71622.1 - 0.4 10.8 2.5 1.5 8.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2540) DUF5394 PF17372.2 KIK71622.1 - 0.76 9.3 5.2 1.1 8.7 5.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5394) DUF4279 PF14106.6 KIK71622.1 - 2.1 8.5 5.6 3.2e+02 1.5 0.0 5.9 4 2 4 8 8 8 0 Domain of unknown function (DUF4279) DUF5122 PF17164.4 KIK71622.1 - 4.6 7.6 22.8 65 3.9 0.1 8.9 10 0 0 10 10 9 0 Domain of unknown function (DUF5122) beta-propeller CHASE7 PF17151.4 KIK71622.1 - 5.4 6.6 6.2 78 2.8 0.0 5.2 5 2 3 8 8 7 0 Periplasmic sensor domain Cuticle_4 PF15955.5 KIK71622.1 - 7.2 7.4 14.0 32 5.3 0.0 6.5 8 0 0 8 8 7 0 Cuticle protein Glyco_hydro_47 PF01532.20 KIK71625.1 - 6.3e-10 38.5 0.0 7.2e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 KIK71626.1 - 1.1e-73 241.2 22.3 1.1e-09 38.8 0.1 8.0 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71626.1 - 5e-30 103.7 0.6 0.0029 17.9 0.0 7.1 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71626.1 - 4.2e-20 71.2 6.6 0.19 11.7 0.0 7.8 7 1 0 7 7 7 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71626.1 - 2.5e-11 43.1 0.4 0.33 9.8 0.0 6.8 1 1 6 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK71626.1 - 2.5e-08 33.6 0.0 0.35 10.2 0.0 5.1 4 1 0 4 4 4 3 WD40-like domain Frtz PF11768.8 KIK71626.1 - 2.5e-07 29.4 0.0 1.5 7.0 0.0 4.9 3 2 2 5 5 5 3 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KIK71626.1 - 4.4e-06 26.7 0.0 0.061 13.2 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KIK71626.1 - 0.00011 21.8 11.9 12 5.7 0.0 7.5 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature PQQ PF01011.21 KIK71626.1 - 0.00098 18.9 0.0 67 3.7 0.0 5.7 6 0 0 6 6 6 0 PQQ enzyme repeat dsrm PF00035.26 KIK71626.1 - 0.0017 19.0 2.8 23 5.8 0.0 5.2 6 0 0 6 6 6 0 Double-stranded RNA binding motif FeThRed_A PF02941.15 KIK71626.1 - 0.0063 16.6 1.2 6.1 7.1 0.1 4.5 3 2 3 6 6 6 1 Ferredoxin thioredoxin reductase variable alpha chain Nup160 PF11715.8 KIK71626.1 - 0.0099 14.6 0.0 13 4.3 0.0 3.6 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.11 KIK71626.1 - 0.013 14.4 0.0 12 4.6 0.0 3.5 1 1 2 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) Kelch_1 PF01344.25 KIK71626.1 - 0.027 14.1 0.1 5.9 6.6 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Nbas_N PF15492.6 KIK71626.1 - 0.042 13.2 4.9 23 4.2 0.0 4.6 1 1 5 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Kelch_6 PF13964.6 KIK71626.1 - 0.044 14.1 1.2 68 4.0 0.0 4.9 6 0 0 6 6 6 0 Kelch motif DUF4875 PF16175.5 KIK71626.1 - 0.16 12.1 10.0 13 5.9 0.4 5.0 1 1 3 5 5 5 0 Domain of unknown function (DUF4875) Cuticle_4 PF15955.5 KIK71626.1 - 0.59 10.9 3.1 71 4.2 0.1 4.1 6 0 0 6 6 5 0 Cuticle protein WD40 PF00400.32 KIK71627.1 - 4.2e-32 109.7 4.3 3.5e-08 34.0 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71627.1 - 2.1e-15 56.8 0.0 2.1e-05 24.7 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71627.1 - 4.4e-10 39.2 0.1 0.081 12.9 0.0 3.9 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK71627.1 - 2.4e-06 27.6 0.0 3.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 KIK71627.1 - 1.2e-05 25.3 0.1 0.17 11.6 0.0 2.9 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain CHAP PF05257.16 KIK71627.1 - 0.0028 18.2 0.3 14 6.3 0.0 3.7 1 1 3 4 4 4 0 CHAP domain Ge1_WD40 PF16529.5 KIK71627.1 - 0.0066 15.4 0.0 4.4 6.2 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK71627.1 - 0.0094 15.6 2.8 25 4.7 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KIK71627.1 - 0.056 12.0 0.0 0.079 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF5122 PF17164.4 KIK71627.1 - 0.065 13.5 1.1 28 5.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller DUF1513 PF07433.11 KIK71627.1 - 0.13 11.3 0.0 0.49 9.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Ret2_MD PF18528.1 KIK71627.1 - 0.19 12.1 0.0 12 6.3 0.0 2.9 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KIK71627.1 - 0.27 9.5 0.0 10 4.3 0.0 2.6 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyco_hydro_47 PF01532.20 KIK71631.1 - 1.3e-05 24.3 0.0 1.3e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 KIK71632.1 - 1.6e-103 335.7 27.9 4.6e-08 33.6 0.0 11.7 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71632.1 - 9.9e-49 163.6 1.8 1.4e-05 25.3 0.0 11.2 1 1 9 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71632.1 - 7.3e-24 83.1 9.8 0.29 11.1 0.0 11.6 11 0 0 11 11 11 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71632.1 - 1.9e-15 56.7 5.8 3 6.7 0.0 10.7 1 1 8 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK71632.1 - 5.8e-12 45.9 0.0 0.001 19.0 0.0 4.5 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK71632.1 - 1.2e-09 37.0 0.0 3.8 5.7 0.0 7.9 6 2 2 8 8 8 4 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KIK71632.1 - 4.8e-09 35.7 0.0 11 6.1 0.0 8.8 10 0 0 10 10 10 0 PQQ enzyme repeat PQQ_2 PF13360.6 KIK71632.1 - 2.3e-08 33.9 11.2 0.0049 16.5 10.4 4.0 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 KIK71632.1 - 2.3e-08 33.7 0.0 0.58 9.4 0.0 7.1 7 2 2 9 9 9 2 WD40-like domain DHFR_2 PF06442.11 KIK71632.1 - 1.5e-06 28.0 1.7 18 5.2 0.0 7.7 6 2 3 9 9 9 0 R67 dihydrofolate reductase DUF1513 PF07433.11 KIK71632.1 - 2.6e-06 26.7 2.9 7.8 5.5 0.0 6.3 2 2 2 6 6 6 1 Protein of unknown function (DUF1513) CHAP PF05257.16 KIK71632.1 - 0.00019 21.9 9.5 3.4 8.3 0.0 7.2 1 1 4 5 5 5 1 CHAP domain Proteasome_A_N PF10584.9 KIK71632.1 - 0.0045 16.6 25.3 23 4.8 0.0 10.9 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.6 KIK71632.1 - 0.0086 16.3 6.4 22 5.5 0.0 7.0 9 0 0 9 9 7 0 Kelch motif Nup160 PF11715.8 KIK71632.1 - 0.011 14.5 0.0 18 3.8 0.0 5.1 6 2 1 7 7 7 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK71632.1 - 0.013 14.8 7.8 3.3 6.9 0.0 5.9 3 2 6 9 9 9 0 Neuroblastoma-amplified sequence, N terminal Me-amine-dh_H PF06433.11 KIK71632.1 - 0.022 13.6 0.0 29 3.4 0.0 4.4 2 1 3 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) FeThRed_A PF02941.15 KIK71632.1 - 0.043 14.0 0.2 21 5.3 0.0 3.8 2 1 1 4 4 4 0 Ferredoxin thioredoxin reductase variable alpha chain AAA PF00004.29 KIK71633.1 - 0.0027 18.1 0.2 0.0066 16.9 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK71633.1 - 0.0034 17.8 0.0 0.0043 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK71633.1 - 0.0062 17.1 0.0 0.007 16.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK71633.1 - 0.026 14.3 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KIK71633.1 - 0.045 13.3 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KIK71633.1 - 0.055 13.2 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 KIK71633.1 - 0.06 13.3 0.0 0.088 12.7 0.0 1.3 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KIK71633.1 - 0.12 12.7 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK71633.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK71633.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF4502 PF14950.6 KIK71639.1 - 1.1 8.7 7.5 0.044 13.2 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) GvpK PF05121.12 KIK71640.1 - 0.029 14.4 1.6 0.057 13.5 1.6 1.5 1 0 0 1 1 1 0 Gas vesicle protein K WD40 PF00400.32 KIK71641.1 - 7.8e-104 336.7 27.8 3.3e-10 40.4 0.1 10.3 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71641.1 - 5.8e-53 177.2 1.0 0.00014 22.1 0.0 10.1 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71641.1 - 3.5e-24 84.2 11.4 0.29 11.1 0.1 10.4 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71641.1 - 7.9e-18 64.5 3.8 0.82 8.6 0.0 9.7 1 1 8 10 10 10 8 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK71641.1 - 1.1e-14 53.7 0.0 0.76 8.0 0.0 8.1 3 3 3 7 7 7 6 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KIK71641.1 - 1.2e-14 54.6 0.0 0.0022 17.9 0.0 4.9 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KIK71641.1 - 1.9e-08 34.2 9.0 0.0019 17.9 3.3 4.0 1 1 2 3 3 3 3 PQQ-like domain WD40_like PF17005.5 KIK71641.1 - 9.9e-07 28.4 0.0 5.4 6.2 0.0 6.5 8 0 0 8 8 8 1 WD40-like domain DHFR_2 PF06442.11 KIK71641.1 - 1.1e-06 28.4 0.9 5.5 6.9 0.0 7.2 5 3 5 10 10 10 1 R67 dihydrofolate reductase PQQ PF01011.21 KIK71641.1 - 3.6e-05 23.5 0.0 1.4e+02 2.6 0.0 7.3 8 0 0 8 8 8 0 PQQ enzyme repeat Proteasome_A_N PF10584.9 KIK71641.1 - 0.0002 21.0 24.7 39 4.1 0.1 10.4 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature Cuticle_4 PF15955.5 KIK71641.1 - 0.0083 16.8 2.8 1.4e+02 3.2 0.0 6.5 9 0 0 9 9 8 0 Cuticle protein Utp8 PF10395.9 KIK71641.1 - 0.074 11.5 0.0 11 4.3 0.0 3.5 4 0 0 4 4 4 0 Utp8 family Colicin_Ia PF11504.8 KIK71641.1 - 0.37 10.9 8.3 83 3.4 0.0 6.8 9 0 0 9 9 8 0 Colicin Ia AAA_16 PF13191.6 KIK71642.1 - 0.0075 16.7 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK71642.1 - 0.013 16.0 0.0 0.017 15.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIK71642.1 - 0.014 15.8 0.3 0.02 15.3 0.3 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.12 KIK71642.1 - 0.022 14.1 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 KIK71642.1 - 0.03 14.2 0.0 0.045 13.7 0.0 1.3 1 1 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 KIK71642.1 - 0.046 13.4 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 KIK71642.1 - 0.049 13.1 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK71642.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KIK71642.1 - 0.16 11.7 0.1 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Goodbye PF17109.5 KIK71643.1 - 3.1e-06 27.6 0.0 7.1e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Myb_DNA-binding PF00249.31 KIK71643.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK71645.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain PRD PF00874.20 KIK71645.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 1 0 1 1 1 0 PRD domain Peptidase_C48 PF02902.19 KIK71646.1 - 1.1e-09 38.5 0.1 1.7e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 KIK71647.1 - 1e-129 418.6 27.6 1.4e-09 38.4 0.1 12.5 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71647.1 - 6.6e-54 180.2 2.6 0.0029 17.9 0.0 12.2 2 2 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71647.1 - 4.8e-29 99.7 2.4 1.4 9.0 0.0 12.4 12 0 0 12 12 12 8 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71647.1 - 3.3e-18 65.8 2.4 3 6.7 0.0 11.2 2 2 10 12 12 12 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK71647.1 - 5.8e-12 44.7 0.0 3.9 5.7 0.0 9.6 4 1 5 10 10 10 3 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK71647.1 - 1.1e-07 30.7 0.0 0.29 9.6 0.0 5.1 1 1 3 5 5 5 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KIK71647.1 - 1.6e-07 30.9 16.6 43 3.9 0.0 11.9 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature PQQ PF01011.21 KIK71647.1 - 1.6e-06 27.7 0.0 41 4.3 0.0 8.3 10 0 0 10 10 9 0 PQQ enzyme repeat DHFR_2 PF06442.11 KIK71647.1 - 5e-06 26.3 2.7 9.2 6.2 0.0 7.9 7 1 3 10 10 9 1 R67 dihydrofolate reductase PQQ_2 PF13360.6 KIK71647.1 - 8.1e-06 25.6 11.8 0.076 12.6 7.6 4.1 1 1 2 3 3 3 3 PQQ-like domain NACHT PF05729.12 KIK71647.1 - 2.5e-05 24.2 0.0 4.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ret2_MD PF18528.1 KIK71647.1 - 3.7e-05 24.0 0.0 48 4.4 0.0 7.8 7 4 4 11 11 10 0 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40_like PF17005.5 KIK71647.1 - 4.5e-05 22.9 0.0 8.6 5.6 0.0 6.3 6 1 1 8 8 8 1 WD40-like domain AAA PF00004.29 KIK71647.1 - 0.00093 19.6 0.0 0.0034 17.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK71647.1 - 0.0072 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK71647.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK71647.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK71647.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIK71647.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RcpC PF16976.5 KIK71649.1 - 0.008 16.2 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB AAA_16 PF13191.6 KIK71652.1 - 0.0038 17.6 0.0 0.0045 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KIK71652.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KIK71652.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIK71652.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Tub PF01167.18 KIK71652.1 - 0.061 13.1 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Tub family TrwB_AAD_bind PF10412.9 KIK71652.1 - 0.072 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 KIK71652.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.12 KIK71652.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RHSP PF07999.11 KIK71652.1 - 0.18 10.6 0.1 0.82 8.4 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon hot spot protein HSP9_HSP12 PF04119.12 KIK71655.1 - 4.4e-25 87.8 12.2 7.8e-25 87.0 8.8 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.6 KIK71655.1 - 0.22 11.8 3.2 3.7 7.9 0.1 2.7 2 1 0 2 2 2 0 MT0933-like antitoxin protein TnpW PF14202.6 KIK71655.1 - 0.5 10.2 2.1 20 5.1 0.2 2.7 2 0 0 2 2 2 0 Transposon-encoded protein TnpW FAM184 PF15665.5 KIK71656.1 - 0.015 15.1 5.7 0.015 15.1 5.7 2.6 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B DUF2203 PF09969.9 KIK71656.1 - 0.52 11.0 4.7 0.3 11.8 0.7 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF3552 PF12072.8 KIK71656.1 - 2.3 7.6 12.5 0.17 11.3 5.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) DivIC PF04977.15 KIK71656.1 - 5.1 7.0 7.9 5.1 6.9 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator CCDC-167 PF15188.6 KIK71656.1 - 7.7 6.9 11.7 29 5.1 0.1 3.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Peptidase_S10 PF00450.22 KIK71657.1 - 1.1e-57 196.4 0.0 1.4e-57 196.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2920 PF11144.8 KIK71657.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) WD40 PF00400.32 KIK71658.1 - 9.1e-67 219.4 19.4 3.1e-09 37.3 0.1 8.8 7 1 1 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71658.1 - 7.1e-18 64.7 1.9 0.064 13.6 0.0 6.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71658.1 - 6.1e-17 61.1 4.0 1.3 9.0 0.0 8.4 8 0 0 8 8 8 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71658.1 - 4.5e-09 35.7 1.0 2.8 6.8 0.0 6.8 1 1 5 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK71658.1 - 1.5e-06 28.2 0.0 4e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK71658.1 - 9.3e-06 26.1 0.1 9.3e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Goodbye PF17109.5 KIK71658.1 - 4.1e-05 24.0 0.3 0.00029 21.3 0.0 2.6 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain WD40_like PF17005.5 KIK71658.1 - 0.00051 19.5 0.0 31 3.7 0.0 5.1 5 1 1 6 6 6 0 WD40-like domain AAA_16 PF13191.6 KIK71658.1 - 0.00079 19.8 0.0 0.0073 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Gmad1 PF10647.9 KIK71658.1 - 0.001 18.9 1.6 0.15 11.8 0.1 3.6 1 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain AAA_7 PF12775.7 KIK71658.1 - 0.0019 17.8 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Herpes_UL69 PF05459.12 KIK71658.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family Nup160 PF11715.8 KIK71658.1 - 0.038 12.7 0.3 33 2.9 0.0 3.9 2 1 2 5 5 5 0 Nucleoporin Nup120/160 DHFR_2 PF06442.11 KIK71658.1 - 0.089 12.6 0.3 14 5.6 0.0 3.8 3 1 1 4 4 3 0 R67 dihydrofolate reductase Nbas_N PF15492.6 KIK71658.1 - 0.15 11.3 1.0 5.5 6.2 0.0 3.5 1 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 KIK71658.1 - 0.33 10.7 14.6 46 3.8 0.1 7.7 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature RBD-FIP PF09457.10 KIK71658.1 - 0.65 10.0 3.6 3.8 7.5 1.4 2.7 2 0 0 2 2 2 0 FIP domain DUF4875 PF16175.5 KIK71658.1 - 7.8 6.7 9.8 20 5.3 0.1 5.0 2 1 1 5 5 5 0 Domain of unknown function (DUF4875) MBOAT_2 PF13813.6 KIK71659.1 - 5e-22 78.0 3.4 1.1e-21 76.9 3.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Mito_carr PF00153.27 KIK71661.1 - 2.4e-62 206.9 5.5 1.6e-22 79.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.13 KIK71661.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MBOAT_2 PF13813.6 KIK71663.1 - 3.3e-21 75.4 3.5 8.1e-21 74.1 3.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FtsK_4TM PF13491.6 KIK71665.1 - 0.23 11.2 5.7 0.12 12.0 1.7 2.1 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE polyprenyl_synt PF00348.17 KIK71667.1 - 5e-47 160.1 0.0 6.2e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DNA_pol_phi PF04931.13 KIK71668.1 - 0.97 7.5 30.1 0.35 8.9 16.2 2.0 2 0 0 2 2 2 0 DNA polymerase phi RXT2_N PF08595.11 KIK71668.1 - 1.5 8.8 22.4 0.45 10.5 1.2 2.7 2 1 0 2 2 2 0 RXT2-like, N-terminal DUF5102 PF17104.5 KIK71668.1 - 8.3 6.4 17.8 0.23 11.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) SR-25 PF10500.9 KIK71669.1 - 0.016 14.8 6.6 0.016 14.8 6.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KIK71669.1 - 0.4 10.4 4.4 0.42 10.3 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pkinase PF00069.25 KIK71670.1 - 1.1e-56 192.1 0.0 4e-48 164.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71670.1 - 4.3e-22 78.6 0.0 2e-10 40.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.24 KIK71670.1 - 0.001 19.7 10.4 0.015 16.0 10.4 3.3 1 1 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 KIK71670.1 - 0.0092 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK71670.1 - 0.021 14.4 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4710 PF15828.5 KIK71670.1 - 0.036 14.2 0.7 0.17 12.0 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) adh_short PF00106.25 KIK71671.1 - 2.8e-39 134.6 0.0 3.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK71671.1 - 6.1e-31 107.8 0.0 7.9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK71671.1 - 2.2e-10 40.8 0.1 3.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK71671.1 - 0.0067 15.8 0.1 0.42 9.9 0.0 2.3 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KIK71671.1 - 0.054 13.3 0.5 0.18 11.6 0.4 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 KIK71671.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK71672.1 - 2.4e-37 128.3 0.0 2.9e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK71672.1 - 8.2e-30 104.1 0.1 1e-29 103.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK71672.1 - 9.3e-10 38.7 0.2 1.5e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Hema_stalk PF08720.10 KIK71672.1 - 0.013 15.2 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk THF_DHG_CYH_C PF02882.19 KIK71672.1 - 0.027 13.8 0.2 1.4 8.2 0.0 2.2 1 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KIK71672.1 - 0.067 12.6 0.6 0.17 11.3 0.6 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIK71673.1 - 1.2e-41 142.4 0.0 1.4e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK71673.1 - 6.9e-34 117.4 0.1 8.9e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK71673.1 - 4.5e-12 46.2 0.1 6.6e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK71673.1 - 0.001 18.4 0.3 0.57 9.5 0.0 2.3 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KIK71673.1 - 0.0037 16.8 0.4 0.0099 15.4 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIK71673.1 - 0.054 12.6 0.0 0.074 12.2 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KIK71674.1 - 1.9e-41 141.7 0.1 2.3e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK71674.1 - 1.5e-34 119.6 0.3 1.9e-34 119.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK71674.1 - 4.7e-13 49.4 0.9 6.8e-13 48.9 0.9 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIK71674.1 - 0.00016 21.0 0.3 0.046 13.0 0.0 2.2 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KIK71674.1 - 0.0012 18.5 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KIK71674.1 - 0.0015 18.0 0.4 0.0098 15.4 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIK71674.1 - 0.023 13.8 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KIK71675.1 - 7.4e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK71675.1 - 0.00048 19.6 0.0 0.00071 19.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase Ribosomal_L39 PF00832.20 KIK71676.1 - 3.2e-22 77.9 9.3 3.7e-22 77.7 9.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 KIK71676.1 - 0.052 13.1 0.5 0.051 13.1 0.5 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 Oxidored_FMN PF00724.20 KIK71677.1 - 1.3e-93 314.0 0.0 1.5e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GMC_oxred_N PF00732.19 KIK71679.1 - 6.5e-58 196.4 0.0 8.9e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK71679.1 - 7.3e-33 114.1 0.0 1.3e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK71679.1 - 0.0017 17.5 0.5 0.0027 16.8 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK71679.1 - 0.0069 16.0 3.8 0.019 14.5 3.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK71679.1 - 0.007 16.6 1.4 0.021 15.0 1.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK71679.1 - 0.011 15.0 0.7 0.044 13.0 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK71679.1 - 0.022 14.0 3.5 0.78 8.9 1.3 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK71679.1 - 0.11 11.8 0.2 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KIK71679.1 - 0.18 10.9 2.8 0.24 10.4 1.7 1.7 2 0 0 2 2 2 0 FAD binding domain Fanconi_A_N PF15865.5 KIK71681.1 - 0.035 13.5 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Rad60-SLD PF11976.8 KIK71681.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 KIK71682.1 - 7.9e-66 222.1 0.0 9.7e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71682.1 - 1.1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK71682.1 - 7.7e-06 25.1 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK71682.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK71682.1 - 0.00075 18.9 0.0 0.0021 17.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK71682.1 - 0.0057 16.0 0.0 0.054 12.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK71682.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KIK71682.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NAD_binding_1 PF00175.21 KIK71683.1 - 7.7e-24 84.5 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK71683.1 - 4.5e-17 62.2 0.0 7.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK71683.1 - 3.3e-06 27.3 0.1 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF5336 PF17270.2 KIK71683.1 - 0.0035 17.0 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5336) FAD_binding_9 PF08021.11 KIK71683.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DPBB_1 PF03330.18 KIK71685.1 - 0.00013 22.2 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KIK71685.1 - 0.06 13.5 0.2 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 Cerato-platanin GPI-anchored PF10342.9 KIK71686.1 - 1.8e-08 35.0 0.5 2.3e-08 34.7 0.5 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PPC PF04151.15 KIK71686.1 - 0.015 16.4 2.5 0.037 15.1 2.5 1.8 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain GPI-anchored PF10342.9 KIK71687.1 - 2.3e-07 31.5 0.3 3e-07 31.1 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family IDO PF01231.18 KIK71688.1 - 1.2e-08 34.2 0.0 1e-06 27.8 0.0 3.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase GFA PF04828.14 KIK71689.1 - 2.1e-11 44.0 3.6 3.7e-11 43.2 3.6 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fer4_2 PF12797.7 KIK71689.1 - 0.029 14.5 0.5 0.029 14.5 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain NACHT PF05729.12 KIK71690.1 - 1.4e-08 34.9 0.0 4.1e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK71690.1 - 5.4e-08 33.4 2.1 1.9e-06 28.4 0.0 3.3 3 0 0 3 3 2 1 AAA ATPase domain WD40 PF00400.32 KIK71690.1 - 5.8e-08 33.3 5.0 0.038 14.9 0.1 7.4 8 0 0 8 8 7 1 WD domain, G-beta repeat AAA_25 PF13481.6 KIK71690.1 - 2.2e-07 30.7 2.4 0.13 11.8 0.0 4.7 3 1 2 5 5 5 3 AAA domain NB-ARC PF00931.22 KIK71690.1 - 2e-05 23.9 0.0 7.1e-05 22.1 0.0 2.0 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK71690.1 - 6.3e-05 23.4 0.0 0.00027 21.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK71690.1 - 0.00061 20.1 0.2 0.0059 16.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain ANAPC4_WD40 PF12894.7 KIK71690.1 - 0.0039 17.4 0.0 0.046 14.0 0.0 2.9 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 4 WD40 domain Parvo_NS1 PF01057.17 KIK71690.1 - 0.0073 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KIK71690.1 - 0.021 14.6 0.0 0.072 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK71690.1 - 0.025 14.9 0.0 0.07 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK71690.1 - 0.089 13.0 0.2 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PQQ PF01011.21 KIK71690.1 - 0.1 12.6 0.4 3.6 7.7 0.1 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Torsin PF06309.11 KIK71690.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Torsin APS_kinase PF01583.20 KIK71690.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KIK71690.1 - 0.48 10.9 0.0 0.48 10.9 0.0 2.6 2 0 0 2 2 1 0 ABC transporter KAP_NTPase PF07693.14 KIK71690.1 - 0.66 9.2 7.1 1.2 8.3 0.1 2.8 2 1 0 3 3 2 0 KAP family P-loop domain Sld7_C PF18596.1 KIK71692.1 - 6.3e-05 23.0 0.1 0.00014 21.9 0.1 1.7 1 0 0 1 1 1 1 Sld7 C-terminal domain RSB_motif PF16294.5 KIK71692.1 - 0.017 15.3 6.5 0.032 14.5 6.5 1.4 1 1 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif AAA_16 PF13191.6 KIK71694.1 - 4.7e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK71694.1 - 0.0006 18.8 0.0 0.00089 18.3 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 KIK71694.1 - 0.0093 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RHSP PF07999.11 KIK71694.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein AAA_5 PF07728.14 KIK71694.1 - 0.022 14.7 0.0 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK71694.1 - 0.031 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KIK71694.1 - 0.034 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK71694.1 - 0.035 14.4 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK71694.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KIK71694.1 - 0.073 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK71694.1 - 0.083 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK71694.1 - 0.097 13.2 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 KIK71694.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KIK71694.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK71694.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIK71694.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_E PF05680.12 KIK71695.1 - 1e-21 77.1 0.1 1.2e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Casc1_N PF15927.5 KIK71695.1 - 0.05 13.3 2.6 0.054 13.2 2.6 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF349 PF03993.12 KIK71695.1 - 0.19 12.0 5.5 0.29 11.4 5.5 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) GMC_oxred_N PF00732.19 KIK71696.1 - 1.9e-57 194.9 0.0 2.6e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK71696.1 - 8.3e-32 110.7 0.0 1.5e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK71696.1 - 0.0019 18.4 0.2 0.0076 16.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK71696.1 - 0.002 17.2 0.4 0.0031 16.6 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK71696.1 - 0.0068 15.7 0.8 0.017 14.4 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK71696.1 - 0.0095 15.1 2.6 0.065 12.3 1.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK71696.1 - 0.012 14.8 1.8 0.71 9.1 0.6 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK71696.1 - 0.078 12.5 4.0 0.2 11.2 4.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK71696.1 - 0.096 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MADF_DNA_bdg PF10545.9 KIK71697.1 - 0.025 14.9 0.3 0.066 13.5 0.1 1.7 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Retrotrans_gag PF03732.17 KIK71697.1 - 0.037 14.3 0.1 0.14 12.5 0.1 1.7 1 1 1 2 2 2 0 Retrotransposon gag protein Glyco_hydro_46 PF01374.18 KIK71697.1 - 0.085 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 DUF802 PF05650.11 KIK71697.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF802) WD40 PF00400.32 KIK71698.1 - 5.1e-88 286.6 25.0 4.5e-09 36.8 0.2 9.1 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71698.1 - 1.2e-39 134.4 0.0 0.01 16.1 0.0 9.0 1 1 8 9 9 9 9 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71698.1 - 4.6e-20 71.0 14.4 0.64 10.0 0.0 9.6 9 0 0 9 9 9 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71698.1 - 6.3e-16 58.2 4.0 0.12 11.3 0.0 8.8 2 2 7 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein DHFR_2 PF06442.11 KIK71698.1 - 2.2e-10 40.2 2.2 0.18 11.7 0.0 7.6 4 1 4 8 8 8 2 R67 dihydrofolate reductase Frtz PF11768.8 KIK71698.1 - 9.1e-10 37.5 0.0 1.7 6.9 0.0 6.5 4 3 2 6 6 6 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KIK71698.1 - 2e-07 30.6 0.0 27 4.9 0.0 7.3 8 0 0 8 8 8 0 PQQ enzyme repeat CHAP PF05257.16 KIK71698.1 - 9.6e-07 29.3 7.8 0.54 10.9 0.0 6.3 2 1 2 4 4 4 1 CHAP domain Nup160 PF11715.8 KIK71698.1 - 8.4e-06 24.7 0.0 5 5.6 0.0 6.4 4 2 2 7 7 7 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK71698.1 - 1.2e-05 24.0 0.2 0.33 9.4 0.0 4.3 2 1 3 5 5 5 1 Cytochrome D1 heme domain FeThRed_A PF02941.15 KIK71698.1 - 1.9e-05 24.7 0.4 1 9.6 0.0 4.8 4 1 0 5 5 5 1 Ferredoxin thioredoxin reductase variable alpha chain PQQ_2 PF13360.6 KIK71698.1 - 2.2e-05 24.2 2.5 0.00052 19.7 0.8 3.2 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.6 KIK71698.1 - 7.8e-05 22.1 5.7 25 4.0 0.0 7.4 3 2 5 9 9 9 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK71698.1 - 0.00013 21.4 0.0 41 3.4 0.0 5.8 6 1 1 7 7 7 0 WD40-like domain Proteasome_A_N PF10584.9 KIK71698.1 - 0.00022 20.8 29.7 2.5 7.9 0.2 11.8 14 0 0 14 14 14 1 Proteasome subunit A N-terminal signature DUF3553 PF12073.8 KIK71698.1 - 0.0013 18.4 0.0 7.3 6.4 0.0 5.4 7 0 0 7 7 7 1 Protein of unknown function (DUF3553) HARP PF07443.13 KIK71698.1 - 0.02 14.5 1.4 85 2.9 0.0 4.9 5 0 0 5 5 5 0 HepA-related protein (HARP) DUF2574 PF10836.8 KIK71698.1 - 0.031 14.2 0.0 14 5.7 0.0 4.3 5 1 0 5 5 5 0 Protein of unknown function (DUF2574) PQQ_3 PF13570.6 KIK71698.1 - 0.069 13.7 5.7 22 5.7 0.1 5.8 4 2 4 8 8 7 0 PQQ-like domain DUF2239 PF09998.9 KIK71698.1 - 0.086 12.6 0.0 11 5.8 0.0 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2239) Cuticle_4 PF15955.5 KIK71698.1 - 5.6 7.7 6.1 2.5e+02 2.5 0.0 4.9 5 1 0 5 5 5 0 Cuticle protein PIG-P PF08510.12 KIK71699.1 - 5.9e-31 106.9 0.9 7.1e-31 106.6 0.9 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KIK71699.1 - 0.0029 17.9 6.9 0.0062 16.8 6.9 1.5 1 1 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) FA_desaturase PF00487.24 KIK71699.1 - 0.083 12.7 1.3 0.12 12.2 1.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Ndc1_Nup PF09531.10 KIK71699.1 - 0.095 11.4 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAF1C_H4-bd PF12265.8 KIK71702.1 - 4.3e-30 103.8 0.6 1e-29 102.6 0.3 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KIK71702.1 - 9.7e-21 73.7 9.1 1.2e-05 25.9 0.3 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Frtz PF11768.8 KIK71702.1 - 0.0053 15.1 0.0 0.0086 14.4 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz RAMP4 PF06624.12 KIK71703.1 - 3.4e-22 78.2 0.0 3.8e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 EphA2_TM PF14575.6 KIK71704.1 - 0.016 16.1 0.3 0.068 14.1 0.3 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIK71704.1 - 0.027 13.3 0.1 0.073 11.9 0.0 1.7 2 0 0 2 2 2 0 Amnionless SLX9 PF15341.6 KIK71704.1 - 0.032 14.6 2.1 0.068 13.6 2.1 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 CYYR1 PF10873.8 KIK71704.1 - 0.17 12.3 0.1 0.33 11.4 0.1 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Pkinase PF00069.25 KIK71706.1 - 2e-08 34.0 0.0 2.4e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71706.1 - 0.019 14.3 0.0 0.31 10.3 0.0 2.4 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KIK71707.1 - 3.9e-10 39.5 0.0 3.1e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK71707.1 - 9.6e-06 25.1 0.0 0.00013 21.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RPA_interact_N PF14766.6 KIK71708.1 - 0.26 11.0 0.2 0.41 10.3 0.2 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal BatA PF07584.11 KIK71709.1 - 0.063 13.7 0.1 0.28 11.6 0.1 2.1 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal AAA_16 PF13191.6 KIK71710.1 - 8.1e-06 26.3 0.0 0.00047 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK71710.1 - 1.7e-05 24.8 0.0 2.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK71710.1 - 2.7e-05 23.5 0.0 3.5e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK71710.1 - 0.0027 18.0 0.0 0.0039 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KIK71710.1 - 0.0048 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein DUF5457 PF17540.2 KIK71710.1 - 0.013 15.6 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5457) TrwB_AAD_bind PF10412.9 KIK71710.1 - 0.04 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 KIK71710.1 - 0.16 11.9 0.0 0.79 9.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KIK71710.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dopey_N PF04118.14 KIK71711.1 - 2.8e-111 371.5 0.1 1.1e-110 369.5 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal Cohesin_HEAT PF12765.7 KIK71711.1 - 0.098 13.0 0.1 0.54 10.6 0.1 2.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF1708 PF08101.11 KIK71712.1 - 1.3e-17 64.2 0.0 2e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) WD40 PF00400.32 KIK71713.1 - 6.1e-64 210.4 25.7 3e-09 37.3 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK71713.1 - 4.7e-25 87.7 0.8 0.038 14.3 0.0 7.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK71713.1 - 1.1e-15 57.0 6.4 1.8 8.6 0.0 7.6 7 0 0 7 7 7 6 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK71713.1 - 1.8e-12 46.9 0.4 0.52 9.2 0.0 6.7 1 1 6 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK71713.1 - 3.4e-06 27.6 0.0 1.1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK71713.1 - 8.7e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK71713.1 - 2.9e-05 24.5 0.0 0.00025 21.5 0.0 2.7 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Frtz PF11768.8 KIK71713.1 - 2.9e-05 22.6 0.0 0.04 12.2 0.0 4.0 5 0 0 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK71713.1 - 0.0002 20.9 4.8 43 3.9 0.1 6.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40_like PF17005.5 KIK71713.1 - 0.0012 18.2 0.0 0.086 12.1 0.0 3.3 3 1 1 4 4 4 1 WD40-like domain AAA_7 PF12775.7 KIK71713.1 - 0.01 15.4 0.3 0.021 14.3 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIK71713.1 - 0.015 14.6 0.0 0.041 13.2 0.0 1.8 1 1 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 KIK71713.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KIK71713.1 - 0.02 15.2 0.0 0.089 13.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK71713.1 - 0.023 15.2 0.0 0.08 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK71713.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Nbas_N PF15492.6 KIK71713.1 - 0.091 12.1 1.7 25 4.1 0.0 3.9 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF815 PF05673.13 KIK71713.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.14 KIK71713.1 - 0.2 10.8 0.8 0.87 8.7 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.6 KIK71715.1 - 0.00011 22.6 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK71715.1 - 0.00044 20.2 0.0 0.00055 19.9 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK71715.1 - 0.0025 18.3 0.4 0.013 15.9 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK71715.1 - 0.0029 18.2 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK71715.1 - 0.0032 17.0 0.0 0.004 16.7 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KIK71715.1 - 0.06 13.6 0.0 0.082 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK71715.1 - 0.063 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 KIK71715.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Goodbye PF17109.5 KIK71716.1 - 2e-09 37.9 0.1 2.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain DDE_Tnp_4 PF13359.6 KIK71719.1 - 3.4e-07 30.1 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Gymnopus_luxurians_FD-317_M1-Gymlu1/GCA_000827265.1_Gymlu1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Gymnopus_luxurians_FD-317_M1-Gymlu1/GCA_000827265.1_Gymlu1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Gymnopus_luxurians_FD-317_M1-Gymlu1/GCA_000827265.1_Gymlu1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Gymnopus_luxurians_FD-317_M1-Gymlu1/GCA_000827265.1_Gymlu1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 22:38:16 2019 # [ok]